UI - 98034908 AU - Corney BG AU - Colley J AU - Graham GC TI - Simplified analysis of pathogenic leptospiral serovars by random amplified polymorphic DNA fingerprinting [In Process Citation] LA - Eng DA - 971120 DP - 1997 Nov IS - 0022-2615 TA - J Med Microbiol PG - 927-32 SB - M CY - ENGLAND IP - 11 VI - 46 JC - J2N AA - AUTHOR AB - A rapid, simplified procedure combining random amplified polymorphic DNA (RAPD) fingerprinting of boiled cultures with high resolution agarose gel electrophoresis was used to compare strains from 46 pathogenic leptospiral serovars. The serovars were placed in eight groups on the basis of RAPD profile similarities. Groups 1-7 corresponded with the genome species Leptospira interrogans, L. borgpetersenii, L. santarosai, L. noguchii, L. weilii, L. kirschneri and L. meyeri. The eighth group did not correspond with a known genome species and may represent a new genome species. Primer choice determined the degree of discrimination possible between closely related serovars and genotypes. This procedure, unlike other procedures used for analysing taxonomic relationships between leptospiral serovars, does not require extensive DNA purification, polyacrylamide gel electrophoresis or autoradiography. AD - Rockhampton Veterinary Laboratory, Department of Primary Industries, Queensland, Australia. RO - O:099 PMID- 9368533 SO - J Med Microbiol 1997 Nov;46(11):927-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [4 nucleotide links] [104 medline neighbors] UI - 98012483 AU - Woo TH AU - Patel BK AU - Smythe LD AU - Symonds ML AU - Norris MA AU - Dohnt MF TI - Comparison of two PCR methods for rapid identification of Leptospira genospecies interrogans. LA - Eng MH - Comparative Study MH - DNA, Ribosomal/chemistry MH - Leptospira interrogans/classification/*isolation & purification MH - Polymerase Chain Reaction/*methods MH - Polymorphism, Restriction Fragment Length MH - RNA, Ribosomal, 16S/genetics MH - Support, Non-U.S. Gov't RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 971120 DP - 1997 Oct 15 IS - 0378-1097 TA - FEMS Microbiol Lett PG - 169-77 SB - M CY - NETHERLANDS IP - 2 VI - 155 JC - FML AA - Author EM - 9801 AB - Based on (i) an analysis of Leptospira 16S rDNA sequences determined by us and of those from databases and (ii) a previously published finding that restriction fragment length polymorphisms (RFLPs) within the Leptospira 16S and 23S rDNA were detected by nine restriction enzymes and these RFLPs allowed categorisation of Leptospira into eight genospecies, we predicted that one particular DdeI restriction site polymorphism within 16S rDNA could be independently used for identifications of Leptospira strains belonging to the genospecies interrogans. Two PCR-based methods, namely allele-specific amplification (ASA) and PCR-RFLP, were tested for the rapid detection of the DdeI restriction site polymorphism. One or two representative strains from each of nine genospecies were tested by ASA, whereas 73 strains from nine genospecies and two field isolates were tested by PCR- RFLP. Our experiments showed that the ASA method was not as specific as intended, but the PCR-RFLP method was useful for rapid identifications of the genospecies interrogans. We have not only confirmed a previous finding and extended the number of samples particularly from the genospecies biflexa, weilii, and inadai, but also simplified a previous PCR-RFLP protocol. AD - School of Biomolecular and Biomedical Sciences, Faculty of Science and Technology, Griffith University, Brisbane, Australia. PMID- 9351198 SO - FEMS Microbiol Lett 1997 Oct 15;155(2):169-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 98001777 AU - Surujballi O AU - Henning D AU - Marenger R AU - Howlett C TI - Development of a monoclonal antibody-based competitive enzyme-linked immunosorbent assay for the detection of Leptospira borgpetersenii serovar hardjo type hardjobovis antibodies in bovine sera [In Process Citation] LA - Eng DA - 971025 DP - 1997 Oct IS - 0830-9000 TA - Can J Vet Res PG - 267-74 SB - M CY - CANADA IP - 4 VI - 61 JC - CKL AA - AUTHOR AB - A murine monoclonal antibody (designated M553) that binds to an epitope on whole cell antigens prepared from Leptospira borgpetersenii serovar hardjo type hardjobovis and Leptospira interrogans serovar hardjo type hardjoprajitno, was produced and incorporated into a competitive enzyme- linked immunosorbent assay for the detection of bovine antibodies to serovar hardjo. The epitope recognized by M553 was susceptible to periodate oxidation. The M553 antibody was characterized by western blot with hardjobovis whole cell antigen. This antibody does not cross- react with whole cell antigens prepared from 11 other pathogenic Leptospira serovars, or, Leptospira biflexa serovar patoc. The sensitivity estimate of the competitive ELISA was 100% with field sera (n = 165) with serovar hardjo microscopic agglutination test (MAT) titres of > or = 100. The specificity estimate was 100% with sera (n = 128) obtained from a specific pathogen free herd of cattle that were negative in the MAT at a dilution of 1:100 for serovars hardjo, pomona, sejroe, copenhageni, canicola, and grippotyphosa. The specificity estimate with field sera (n = 301) with serovar hardjo MAT titres of < 100, was 98% (95% confidence interval = +/- 1.58%). There was no cross- reactivity with field sera (n = 306) with serovar pomona titres > or = 100 and serovar hardjo titres < 100. The specificity estimate with the combined populations of sera with serovar hardjo MAT titres of < 100 (n = 735) was 99.18% (95% confidence interval = +/- 0.65%). There was a high level of agreement (kappa = 0.977) between the results of the competitive ELISA and those of the MAT. AD - Agriculture and Agri-Food Canada, Animal Diseases Research Institute, Nepean, Ontario. RO - O:099 PMID- 9342450 SO - Can J Vet Res 1997 Oct;61(4):267-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 98001776 AU - Surujballi OP AU - Marenger RM AU - Eaglesome MD AU - Sugden EA TI - Development and initial evaluation of an indirect enzyme-linked immunosorbent assay for the detection of Leptospira interrogans serovar hardjo antibodies in bovine sera [In Process Citation] LA - Eng DA - 971025 DP - 1997 Oct IS - 0830-9000 TA - Can J Vet Res PG - 260-6 SB - M CY - CANADA IP - 4 VI - 61 JC - CKL AA - AUTHOR AB - Outer sheath antigen from Leptospira interrogans serovar hardjo type hardjoprajitno and acetic acid extracted antigens from serovar hardjo types hardjoprajitno and hardjobovis were evaluated in an immunoassay for ability to detect hyperimmune rabbit serum to serovar hardjo. The degree of cross-reactivity with hyperimmune rabbit sera to L. interrogans serovars pomona, copenhageni, grippotyphosa, canicola and sejroe, and Leptospira biflexa serovar patoc was also measured for each antigen. All of the antigens reacted with the antiserum to L. interrogans serovar hardjo. The outer sheath antigen however, also showed wide cross-reactivity with the antisera to all of the serovars of L. interrogans tested and with the antiserum to L. biflexa serovar patoc. The acetic acid extracted antigen from either type hardjoprajitno, or type hardjobovis, showed a high degree of specificity for serovar hardjo antiserum. The hardjobovis acetic acid extracted antigen was characterized by sodium dodecyl sulfate polyacrylamide gel electrophoresis and immunoblotting, and was incorporated into an indirect ELISA for detection of anti-serovar hardjo antibodies in bovine serum. This ELISA showed a relative specificity of 100% with 156 bovine sera which were negative at a dilution of 1:100 in the microscopic agglutination test (MAT) for L. interrogans serovars hardjo, pomona, sejroe, icterohaemorrhagiae, copenhageni, canicola, and grippotyphosa. The relative sensitivity of this assay with 192 bovine sera which had serovar hardjo MAT titres of > or = 100 was 95.3% (95% confidence limit = 2.99%). The degree of cross-reactivity with 289 bovine sera which had serovar pomona MAT titres of > or = 100 (with no detectable serovar hardjo MAT titres) was approximately 1.0%. This assay was: easily standardized, scored objectively, repeatable, semi-automated and used a non-hazardous antigen that can be routinely prepared in gram amounts. AD - Agriculture and Agri-Food Canada, Animal Diseases Research Institute, Nepean, Ontario. RO - O:099 PMID- 9342449 SO - Can J Vet Res 1997 Oct;61(4):260-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 97469189 AU - Barwick RS AU - Mohammed HO AU - McDonough PL AU - White ME TI - Risk factors associated with the likelihood of leptospiral seropositivity in horses in the state of New York [In Process Citation] LA - Eng DA - 971014 DP - 1997 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1097-103 SB - M CY - UNITED STATES IP - 10 VI - 58 JC - 40C AA - AUTHOR AB - OBJECTIVE: To determine and quantify risk factors associated with exposure of horses to the following serovars of Leptospira interrogans: pomona, autumnalis, and bratislava. ANIMALS: 2,551 horses were randomly selected from a target population during the period of May 1991 to August 1993. PROCEDURES: Blood was collected from the horses and tested for antibodies to serovars, using the microscopic agglutination test. A titer > or = 1:100 indicated seropositivity. Information was collected on each horse, its environment, and each farm's management practices. Logistic regression analysis was used to develop a multidimensional indexing system for indices of exposure and to identify factors significantly-associated with the risk of seropositivity. These indices were: 1) rodent exposure; 2) wildlife exposure; 3) soil and water; and 4) management. RESULTS: Rodent exposure index value was associated with the risk of exposure to all 3 serovars. Management index value was positively associated with the risk of exposure to serovars pomona and bratislava, but not with risk of exposure to serovar autumnalis. Soil and water index value had a positive association with risk of exposure to serovars pomona and autumnalis, but not to serovar bratislava. The wild-life index value and the population density of horses turned out together were associated with the risk of exposure to serovar autumnalis. Age of horse in years was associated nonlinearly (years) and linearly (years) with the risk of exposure to serovars autumnalis and bratislava, and only linearly with the risk of exposure to serovar pomona. CONCLUSION: Risk of seropositivity to the 3 serovars of L interrogans varies according to age, management practices, population density of horses turned out together, and the values of the rodent exposure, wildlife exposure, and soil and water indices. AD - Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA. RO - O:099 PMID- 9328661 SO - Am J Vet Res 1997 Oct;58(10):1097-103 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 97461368 AU - Lin M AU - Surujballi O AU - Nielsen K AU - Nadin-Davis S AU - Randall G TI - Identification of a 35-kilodalton serovar-cross-reactive flagellar protein, FlaB, from Leptospira interrogans by N-terminal sequencing, gene cloning, and sequence analysis. LA - Eng MH - Amino Acid Sequence MH - Antibodies, Bacterial MH - Antibodies, Monoclonal MH - Antibody Specificity MH - Cloning, Molecular MH - Comparative Study MH - Cross Reactions MH - Flagella/*genetics/immunology MH - Flagellin/*genetics/immunology MH - *Genes, Bacterial MH - Leptospira interrogans/classification/genetics/*immunology MH - Molecular Sequence Data MH - Sequence Analysis, DNA MH - Sequence Homology, Amino Acid MH - Serotyping RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 12777-81-0 (Flagellin) RN - 140470-87-7 (flaB protein) PT - JOURNAL ARTICLE DA - 971030 DP - 1997 Oct IS - 0019-9567 TA - Infect Immun PG - 4355-9 SB - M SB - X CY - UNITED STATES IP - 10 VI - 65 JC - GO7 AA - Author EM - 9801 AB - During the screening of antibodies to pathogenic leptospires, a murine monoclonal antibody (designated M138) was found to react with various serovars. An antigen of approximately 35 kDa from Leptospira interrogans serovar pomona, which reacted strongly with M138, was characterized by N-terminal amino acid sequencing and identified as a flagellin, a class B polypeptide subunit (FlaB) of the periplasmic flagella. The gene encoding the FlaB protein, flaB, was amplified from the genomic DNA of several pathogenic serovars by PCR with a single pair of oligonucleotide primers, suggesting that FlaB is highly conserved among these serovars. Cloning and sequence analysis of flaB from serovar pomona revealed that it contains an 849-bp open reading frame with a G + C content of 46.88% which encodes a 283-amino-acid protein with a calculated molecular mass of 31.297 kDa and a predicted pI of 9.065. A sequence comparison of flagellin proteins revealed that the amino acid sequence is most variable in the central portion of the serovar pomona FlaB, which is believed to contain specific sequence information and which may thus be useful in the design of DNA or synthetic peptide probes suitable for the detection of infection with pathogenic leptospires. AD - Animal Diseases Research Institute, Nepean, Ontario, Canada. PMID- 9317049 SI - GENBANK/AF014114 SO - Infect Immun 1997 Oct;65(10):4355-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97461236 AU - Zuerner RL AU - Bolin CA TI - Differentiation of Leptospira interrogans isolates by IS1500 hybridization and PCR assays. LA - Eng MH - Animal MH - Bacterial Typing Techniques MH - Comparative Study MH - Disease Outbreaks MH - Dogs MH - *DNA Insertion Elements MH - Human MH - Leptospira interrogans/*classification/genetics MH - Leptospirosis/epidemiology/microbiology/veterinary MH - Mice MH - Nicaragua/epidemiology MH - *Nucleic Acid Hybridization MH - *Polymerase Chain Reaction MH - Swine MH - Variation (Genetics) RN - 0 (DNA Insertion Elements) PT - JOURNAL ARTICLE DA - 971120 DP - 1997 Oct IS - 0095-1137 TA - J Clin Microbiol PG - 2612-7 SB - M CY - UNITED STATES IP - 10 VI - 35 JC - HSH AA - Author EM - 9801 AB - Genetic variability among Leptospira interrogans (sensu stricto) serovars was assessed by Southern blot hybridization and PCR analyses. The experiments used probes directed to sequences in a recently described insertion element, IS1500. Hybridization analysis showed that IS1500 was present on polymorphic fragments and that differences in these patterns could be used to identify serovars. Hybridization analysis was also useful in discriminating between serovar pomona type kennewicki isolates, making possible the identification of 15 previously unrecognized genetic groups. A PCR assay was developed in which the primers are positioned near the terminal inverted repeats of the element and directed outward. This assay yielded characteristic amplification patterns from isolates, allowing them to be identified. We applied these assays to several new animal isolates of L. interrogans from Nicaragua, which recently had an outbreak of human leptospirosis. Three groups of isolates were identified: one strain of serovar pomona type kennewicki and two genetically distinct groups of isolates which may be genetic intermediates between serovars canicola and portlandvere. The IS-based typing assays described should be useful for epidemiological analysis of leptospirosis. AD - Leptospirosis Reference Center, National Animal Disease Center, USDA Agriculture Research Service, Ames, Iowa 50010, USA. rzuerner@nadc.ars.usda.gov PMID- 9316917 SO - J Clin Microbiol 1997 Oct;35(10):2612-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97438202 TI - From the Centers for Disease Control and Prevention. Outbreak of leptospirosis among white-water rafters--Costa Rica, 1996. LA - Eng MH - Adult MH - Costa Rica/epidemiology MH - *Disease Outbreaks MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology MH - *Recreation MH - Travel MH - United States/epidemiology MH - Water RN - 7732-18-5 (Water) PT - JOURNAL ARTICLE DA - 970925 DP - 1997 Sep 10 IS - 0098-7484 TA - JAMA PG - 808-9 SB - A SB - M SB - X CY - UNITED STATES IP - 10 VI - 278 JC - KFR EM - 9711 PMID- 9293977 NI - A SO - JAMA 1997 Sep 10;278(10):808-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 98016876 AU - Weekes CC AU - Everard CO AU - Levett PN TI - Seroepidemiology of canine leptospirosis on the island of Barbados [In Process Citation] LA - Eng DA - 971107 DP - 1997 Sep IS - 0378-1135 TA - Vet Microbiol PG - 215-22 SB - M CY - NETHERLANDS IP - 2-3 VI - 57 JC - XBW AA - AUTHOR AB - Previous surveillance in Barbados documented the absence of infection with Leptospira serogroup Canicola in dogs. The aim of this study was to survey the current state of canine leptospirosis in Barbados, 10 years after the last survey. Sera from 78 unwanted dogs scheduled for euthanasia and 61 dogs suspected of having acute leptospirosis were tested by microscopic agglutination (MAT) and by an ELISA method adapted for canine IgM and IgG antibodies. The seroprevalence in unwanted dogs was 62% (48/78), at an MAT titre of > or = 100. The majority of animals had low titres, suggestive of previous infection. Serogroup Autumnalis was the most common reactor (45%), followed by serogroups Icterohaemorrhagiae and Australis (each 16%) and Pomona (13%). Serogroup Ballum was uncommon in this group. The seroprevalence determined by MAT in acutely-ill dogs was 75% (46/61). The most common predominant serogroup was Icterohaemorrhagiae (36%) followed by serogroup Australis (13%), while serogroups Autumnalis and Ballum were also of little significance. Paired specimens were available from eight acutely-ill dogs. One animal was seronegative while five dogs showed evidence of seroconversion. An IgM-ELISA titre of > or = 320 was used to confirm current infection in eight of these nine animals. Previous studies in Barbados showed a higher prevalence of serogroup Icterohaemorrhagiae than of Autumnalis, but the relative frequency of these two serogroups may be changing. The high seroprevalence in dogs is of public health concern because the close contact between dogs and man may provide the link between a reservoir in the environment and susceptible humans. AD - Leptospira Laboratory, St. Michael, Barbados. RO - O:099 PMID- 9355256 SO - Vet Microbiol 1997 Sep;57(2-3):215-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97464396 AU - Kuriakose M AU - Eapen CK AU - Paul R TI - Leptospirosis in Kolenchery, Kerala, India: epidemiology, prevalent local serogroups and serovars and a new serovar. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Hemagglutination Tests MH - Human MH - Incidence MH - India/epidemiology MH - Leptospira/genetics/*isolation & purification MH - Leptospirosis/*epidemiology/microbiology MH - Male MH - Middle Age MH - Occupational Diseases/*epidemiology/microbiology MH - Seasons MH - Serologic Tests MH - Serotyping PT - JOURNAL ARTICLE DA - 971118 DP - 1997 Sep IS - 0392-2990 TA - Eur J Epidemiol PG - 691-7 SB - M CY - NETHERLANDS IP - 6 VI - 13 JC - ERE AA - Author EM - 9801 AB - Leptospirosis is the most widespread zoonosis in the world. It is mostly an occupational disease especially in rural areas. Kolenchery is in the midlands of Kerala. The landscape consists of marshy land and dry land interspersed by rivulets and ponds. Irrigation of dry lands for cultivation during the summer months started in mid 1980s after the irrigation projects were commissioned. Cases of leptospirosis were rarely diagnosed in Kolenchery before 1987. Since then a yearly increase in incidence is observed. No major study on either epidemiology or clinical picture has been done on human leptospirosis in Kerala so far. The aim of this study was to define the major clinical presentations, epidemiology of the infection and demonstrate the predominant serogroups and serovars causing the illness in this limited geographical area. The study involves 976 cases of leptospirosis confirmed by culture and/or serological tests. Serogroups Autumnalis, Australis and Icterohaemorrhagiae were the commonest. Mortality rate was 5.32%. The increase in incidence is probably due to the geographical characteristics, continuous moisture of the soil due to irrigation in summer and year-round cultivation making food and cover available to host rodents. Close interaction of humans, animals, soil and water in this region make the spread of leptospirosis to humans easy. Confirmation of cases has been done by enzyme linked immunosorbent assay (ELISA) and/or microscopic agglutination test (MAT) and/or by culture. Serovar identification has been done in 21 cultures isolated from patients. One new serovar belonging to serogroup Australis has been identified from a patient and named serovar Australis bharathy. AD - Department of Medicine, Malankara Orthodox Syrian Church Medical Mission Hospital, Kolenchery, Kerala, India. PMID- 9324217 SO - Eur J Epidemiol 1997 Sep;13(6):691-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 97458138 AU - Dupont H AU - Dupont-Perdrizet D AU - Perie JL AU - Zehner-Hansen S AU - Jarrige B AU - Daijardin JB TI - Leptospirosis: prognostic factors associated with mortality. LA - Eng MH - Adult MH - Aged MH - Cohort Studies MH - Dyspnea/physiopathology MH - Electrocardiography MH - Emergency Medical Services MH - Female MH - Human MH - Intensive Care MH - Leptospirosis/diagnosis/*mortality/physiopathology MH - Leukocyte Count MH - Male MH - Middle Age MH - Multivariate Analysis MH - Oliguria/physiopathology MH - Prognosis MH - Pulmonary Alveoli/radiography MH - Retrospective Studies MH - West Indies/epidemiology PT - JOURNAL ARTICLE DA - 971125 DP - 1997 Sep IS - 1058-4838 TA - Clin Infect Dis PG - 720-4 SB - M CY - UNITED STATES IP - 3 VI - 25 JC - A4J AA - Author EM - 9801 AB - To determine the prognostic factors for leptospirosis, we conducted a retrospective study of data collected in the emergency department of our hospital between 1989 and 1993. Sixty-eight patients, for whom the diagnosis of leptospirosis was based on pertinent clinical and epidemiological data and positive serology, were included in this study. Fifty-six patients (82%) were discharged from the hospital, and 12 (18%) died. Multivariate logistic regression demonstrated that five factors were independently associated with mortality: dyspnea (odds ratio [OR], 11.7; 95% confidence interval [CI], 2.8-48.5; P < .05), oliguria (OR, 9; CI, 2.1-37.9; P < .05); white blood cell count, >12,900/mm3 (OR, 2.5; CI, 1.8-3.5; P < or = .01), repolarization abnormalities on electrocardiograms (OR, 5.9; CI, 1.4-24.8; P < or = .01), and alveolar infiltrates on chest radiographs (OR, 7.3; CI, 1.7- 31.7; P < or = .01). Identification of these factors on admission might provide useful selection criteria for patients who need early transfer to the intensive care unit. AD - Medical, Surgical, and Burn Intensive Care Unit, Pointe-a-Pitre Hospital, Antilles-Guyane University, French West Indies. PMID- 9314467 SO - Clin Infect Dis 1997 Sep;25(3):720-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97430491 AU - Rubel D AU - Seijo A AU - Cernigoi B AU - Viale A AU - Wisnivesky-Colli C TI - [Leptospira interrogans in a canine population of Greater Buenos Aires: variables associated with seropositivity] LA - Spa MH - Age Factors MH - Animal MH - Antibodies, Bacterial/analysis MH - Argentina MH - Comparative Study MH - Dogs/*microbiology MH - English Abstract MH - Female MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/diagnosis/*veterinary MH - Male MH - Sex Factors MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 970926 DP - 1997 Aug IS - 1020-4989 TA - Rev Panam Salud Publica PG - 102-5 CY - UNITED STATES IP - 2 VI - 2 JC - CSL AA - Author EM - 9712 AB - We determined the seroprevalence of leptospirosis in a suburban canine population for the purpose of analyzing the association between different individual and environmental variables and seropositivity for leptospirosis. The study, which was cross-sectional, was performed in July 1992 in a neighborhood of Greater Buenos Aires with approximately 9,500 inhabitants and a canine population of around 2,000 animals. We studied a random sample of 223 dogs and obtained a blood sample from each. Each animal's epidemiologic history was obtained by interviewing the housewife. Serologic measurements were performed by the microagglutination technique with the use of 10 different serotypes of Leptospira interrogans. Of the 223 dogs that were tested, 57% showed seropositivity; 82% of the positive sera coagglutinated with two or more serotypes. The most frequently detected serotypes were canicola and pyrogenes. Seroprevalence in females was less common than in males (P < 0.05) and in puppies less than 1 year old it was less common than in older animals (P < 0.01). Street behavior in the dog and the presence of stagnant water in front of the owner's dwelling were the most important of the risk factors examined. The associations between seropositivity on the one hand and contact with trash deposits, hunting behavior and the presence of rodents inside the dwelling on the other were not statistically significant. Different control measures are discussed. AD - Universidad de Buenos Aires, Facultad de Ciencias Exactas Y Naturales, Buenos Aires, Argentina. paras@biolo.bg.fcen.uba.ar PMID- 9312417 TT - Leptospira interrogans en una poblacion canina del Gran Buenos Aires: variables asociadas con la seropositividad. EA - A SO - Rev Panam Salud Publica 1997 Aug;2(2):102-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97448347 AU - Samina I AU - Brenner J AU - Moalem U AU - Berenstein M AU - Cohen A AU - Peleg BA TI - Enhanced antibody response in cattle against Leptospira hardjo by intradermal vaccination. LA - Eng MH - Administration, Cutaneous MH - Animal MH - Antibodies, Bacterial/*blood MH - Bacterial Vaccines/administration & dosage/*immunology MH - Cattle MH - Female MH - Leptospira/*immunology MH - Vaccination RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 971023 DP - 1997 Aug-Sep IS - 0264-410X TA - Vaccine PG - 1434-6 SB - M CY - ENGLAND IP - 12-13 VI - 15 JC - X6O AA - Author EM - 9712 AB - A commercial killed Leptospira hardjo vaccine (with adjuvant) and non- adjuvanted preparation of the same vaccine were used in comparison of the effectiveness of the intradermal (i.d.) and subcutaneous (s.c.) routes for these vaccines. The tests were conducted in 50 females aged 6-14 months. After the first vaccination, both types of vaccine elicited a very poor antibody response by both routes of vaccination. However, after booster vaccination, the commercial vaccine (with adjuvant) elicited a remarkable immune response which was twice as high by i.d. compared with s.c. vaccination. No local or general adverse reactions were observed after i.d. vaccination with the adjuvanted commercial vaccine (potassium aluminium sulphate). AD - State Laboratory for Vaccine Control, Kimou Veterinary Institute, Bet Dagan, Israel. PMID- 9302757 SO - Vaccine 1997 Aug-Sep;15(12-13):1434-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 97424491 AU - Schwartz DA TI - Emerging and reemerging infections. Progress and challenges in the subspecialty of infectious disease pathology. LA - Eng MH - Animal MH - Cattle MH - Coccidiosis/etiology/pathology MH - Communicable Diseases/etiology/*pathology MH - Creutzfeldt-Jakob Syndrome/etiology/pathology MH - Encephalopathy, Bovine Spongiform/etiology/pathology MH - Hemorrhagic Fever, Ebola/etiology/pathology MH - Human MH - Leptospirosis/etiology/pathology MH - Microspora Infections/etiology/pathology MH - Risk Assessment PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 970919 DP - 1997 Aug IS - 0003-9985 TA - Arch Pathol Lab Med PG - 776-84 SB - A SB - M SB - X CY - UNITED STATES IP - 8 VI - 121 JC - 79Z AA - Author EM - 9711 AB - Emerging and reemerging infections are attracting greater attention from the public health and medical communities. Pathologists and other physicians are increasingly aware of the importance of the subspecialty of infectious disease pathology as a tool for diagnosis, surveillance, and research of emerging infections. In this communication, we describe the role that infectious disease pathologists have played during the last 2 years in broadening our understanding of selected emerging infections, including such examples as new variant Creutzfeldt-Jakob disease and bovine spongiform encephalopathy, leptospirosis, microsporidiosis, Ebola hemorrhagic fever, and cyclosporiasis. The significance of providing pathology services, especially the autopsy, to patients with potentially hazardous communicable diseases is discussed with the supposition that it is unethical to exclude or withhold health care from a patient based on his or her underlying disease or on risk factors for acquiring a disease. The increasing occurrence of infectious diseases imported into the United States and other nations, including human immunodeficiency virus-1 group O, dengue fever, tuberculosis, malaria, diphtheria and cholera in immigrants and travelers, and Ebola virus in nonhuman primates, emphasizes the necessity for pathologists of having competence with infectious disease pathology. It is critical that new generations of pathologists not only be trained in the subspecialty of infectious disease pathology, but that they also be willing participants in the diagnosis and investigation of infectious diseases. The lack of training programs for infectious disease pathologists, as well as the deficiency in infectious disease pathology support for ongoing and future epidemiologic investigations and research, has led to the broadening of pathology services and initiation of a dedicated section of Infectious Disease Pathology at one of the nation's premier public health institutions, the Centers for Disease Control and Prevention in Atlanta, Ga. Together with preexisting groups of medical and veterinary infectious disease pathologists at universities, the Armed Forces Institute of Pathology, the US Army Medical Research Institute of Infectious Diseases, and the National Institutes of Health, this new program will significantly strengthen the capability of the United States to respond to future challenges of emerging and reemerging infections, both in this country and abroad. AD - Department of Pathology, Emory University School of Medicine, Atlanta, Ga, USA. RF - 66 PMID- 9278604 SO - Arch Pathol Lab Med 1997 Aug;121(8):776-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97408342 AU - Hrinivich K AU - Prescott JF TI - Leptospirosis in 2 unrelated dogs. LA - Eng MH - Amylases/blood MH - Animal MH - Antibodies, Bacterial/blood/therapeutic use MH - Blood Cell Count MH - Blood Urea Nitrogen MH - Calcium/blood MH - Canada/epidemiology MH - Case Report MH - Creatinine/blood MH - Dog Diseases/blood/*diagnosis/epidemiology MH - Dogs MH - Female MH - Leptospira/immunology MH - Leptospirosis/blood/diagnosis/*veterinary MH - United States/epidemiology MH - Vaccination/methods/veterinary RN - EC 3.2.1.- (Amylases) RN - 0 (Antibodies, Bacterial) RN - 60-27-5 (Creatinine) RN - 7440-70-2 (Calcium) PT - JOURNAL ARTICLE DA - 971023 DP - 1997 Aug IS - 0008-5286 TA - Can Vet J PG - 509-10 SB - M CY - CANADA IP - 8 VI - 38 JC - CLS EM - 9712 AD - Royal City Animal Hospital, Guelph, Ontario. PMID- 9262862 SO - Can Vet J 1997 Aug;38(8):509-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97401126 AU - Pardo MC AU - Bauman JE AU - Mackowiak M TI - Protection of dogs against canine distemper by vaccination with a canarypox virus recombinant expressing canine distemper virus fusion and hemagglutinin glycoproteins. LA - Eng MH - Animal MH - Antibodies, Viral/blood MH - Avipoxvirus/*immunology MH - Distemper/epidemiology/mortality/*prevention & control MH - Distemper Virus, Canine/*immunology MH - Dogs MH - Female MH - Hemagglutinins, Viral/immunology MH - Incidence MH - Male MH - Morbidity MH - Recombinant Fusion Proteins/immunology MH - *Vaccines, Synthetic MH - *Viral Vaccines RN - 0 (Antibodies, Viral) RN - 0 (Hemagglutinins, Viral) RN - 0 (Recombinant Fusion Proteins) RN - 0 (Vaccines, Synthetic) RN - 0 (Viral Vaccines) PT - JOURNAL ARTICLE DA - 970929 DP - 1997 Aug IS - 0002-9645 TA - Am J Vet Res PG - 833-6 SB - M CY - UNITED STATES IP - 8 VI - 58 JC - 40C AA - Author EM - 9712 AB - OBJECTIVES: To evaluate the safety and efficacy of a live canarypox virus recombinant-canine distemper virus (CDV) combination vaccine against virulent CDV challenge exposure, and to document lack of interference among the other modified-live virus (MLV) components. ANIMALS: 33 specific-pathogen-free (SPF) Beagle pups (7 to 10 weeks old). PROCEDURE: A canarypox virus recombinant-CDV combination vaccine was tested for safety and efficacy along with MLV components (canine adenovirus type 2, canine coronavirus, canine parainfluenza virus, and canine parvovirus) in 26 SPF Beagle pups. The combination vaccine was rehydrated with either Leptospira canicola-L icterohaemorrhagiae combination bacterin (vaccine 1) or sterile diluent (vaccine 2). An additional group of 7 seronegative SPF pups received the control MLV components devoid of the combination vaccine (vaccine 3). Two vaccinations were administered 21 days apart, either IM or SC. The dose of the combination vaccine used to inoculate these pups was 40 times lower than the recommended commercial dose. At 21 days after the booster vaccination, all pups were challenge exposed with a virulent CDV strain, then were observed for 21 days to record morbidity and mortality. RESULTS: Adverse local or generalized reactions were not induced by vaccinations. All vaccinates seroconverted to CDV. Serum antibody titers to MLV components were not different, with or without inclusion of the combination vaccine. After challenge exposure, morbidity and mortality in vaccinates were 0% (0/26); in control dogs, values were 100% morbidity and 86% mortality (6/7). Brain impression smear slides made from all dogs that did not survive challenge exposure were CDV positive by use of a direct fluorescein isothiocyanate method. CONCLUSIONS: The canarypox virus-CDV combination vaccine, administered SC or IM, is a safe product that elicits CDV seroconversion, does not interfere with other vaccine components, and protects vaccinated pups against virulent CDV challenge exposure. AD - Biological Research and Development Department, Rhone Merieux Inc., Athens, GA 30601, USA. PMID- 9256965 SO - Am J Vet Res 1997 Aug;58(8):833-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97398958 AU - Sanghi A AU - Morgan-Capner P AU - Hesketh L AU - Elstein M TI - Zoonotic and viral infection in fetal loss after 12 weeks. LA - Eng MH - Abortion/*microbiology MH - Abortion, Induced MH - Abortion, Missed MH - Chlamydia Infections/complications MH - Cytomegalovirus Infections/complications MH - England MH - Female MH - *Fetal Death MH - Fetus/*abnormalities MH - Human MH - Leptospirosis/complications MH - Listeria Infections/complications MH - Parvoviridae Infections/complications MH - Pregnancy MH - Pregnancy Complications, Infectious/*microbiology MH - Pregnancy Complications, Parasitic/parasitology MH - Rural Health MH - Support, Non-U.S. Gov't MH - Toxoplasmosis/complications MH - Urban Health MH - Virus Diseases/*complications MH - Zoonoses/*transmission PT - JOURNAL ARTICLE DA - 970904 DP - 1997 Aug IS - 0306-5456 TA - Br J Obstet Gynaecol PG - 942-5 SB - A SB - M CY - ENGLAND IP - 8 VI - 104 JC - AZC AA - Author EM - 9711 AB - One hundred and thirty-six women from an urban, rural and farming community were recruited to a study of infectious causes of midtrimester miscarriage (n = 85), stillbirth (n = 32), or termination for developmental (n = 17) or chromosomal (n = 2) abnormalities. No woman had evidence of acute infection with toxoplasma, listeria, leptospira or Chlamydia psittaci (ovine enzootic abortion). One woman had midtrimester miscarriage associated with primary cytomegolovirus infection and five women had evidence of parvovirus B19 infection, although fetal infection was not proven. Zoonoses were not identified as a cause of fetal loss or malformation in this at-risk population, but parvovirus B19 was a significant cause of midtrimester fetal loss. AD - Sharoe Green Hospital, Preston, UK. PMID- 9255087 SO - Br J Obstet Gynaecol 1997 Aug;104(8):942-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 97373876 AU - Winslow WE AU - Merry DJ AU - Pirc ML AU - Devine PL TI - Evaluation of a commercial enzyme-linked immunosorbent assay for detection of immunoglobulin M antibody in diagnosis of human leptospiral infection. LA - Eng MH - Analysis of Variance MH - Antibodies, Bacterial/*analysis MH - Antibody Specificity MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay/*methods MH - Evaluation Studies MH - Human MH - IgM/*analysis MH - Leptospira interrogans/*immunology MH - Leptospirosis/*diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 970904 DP - 1997 Aug IS - 0095-1137 TA - J Clin Microbiol PG - 1938-42 SB - M CY - UNITED STATES IP - 8 VI - 35 JC - HSH AA - Author EM - 9711 AB - The PanBio Leptospira immunoglobulin M (IgM) enzyme-linked immunosorbent assay (ELISA) is a commercially available screening test for the diagnosis of acute leptospiral infection. The ability of the test to diagnose early or recent Leptospira interrogans infection was assessed by testing sera with known microagglutination test (MAT) titers to serovars pomona, hardjo, copenhageni, and australis. The IgM ELISA detected all 41 cases of early or recent leptospiral infection (sensitivity, 100%), with a positive ELISA result seen in many cases before MAT antibody titers reached 1:50. Thirty-eight of 41 patients showed seroconversion (fourfold or greater increase in titer by MAT, 2 of 41 patients had a single sample with elevated titer, and 1 patient from whom leptospires were isolated from a blood sample failed to show MAT titers, despite a seroconversion (negative to positive result) in the ELISA. Follow-up sera obtained from 8 of 12 patients (67%) for 3 to 48 months after the acute stage of illness showed persisting IgM antibody. However, the range of levels detected in these samples (maximum ELISA ratio, 2.0) was lower than the range seen when infection was recent. Reactivity in the IgM ELISA was observed for only 1 of 59 serum samples from asymptomatic donors (specificity, 98%) and 16 of 233 serum samples from patients with Ross River virus, brucella, Epstein- Barr virus, cytomegalovirus, mycoplasma, Q-fever, toxoplasma, hepatitis A virus, Treponema pallidum, or Borrelia burgdorferi infection (specificity, 93%), with the majority of these patients showing lower levels of IgM in comparison to those in patients with leptospiral infection. We conclude that this ELISA is sufficiently sensitive for use as an initial screen for leptospiral infections, with subsequent confirmation of positive test results by MAT. AD - Division of Clinical Microbiology, Institute of Medical and Veterinary Science, Adelaide, South Australia. PMID- 9230359 SO - J Clin Microbiol 1997 Aug;35(8):1938-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] UI - 97425005 AU - Sawae Y TI - [Microbiological tests for determination of specific microbes-- Treponema , Leptospira and Borrelia] LA - Jpn MH - Borrelia/*isolation & purification MH - Human MH - Leptospira interrogans/*isolation & purification MH - Lyme Disease/diagnosis MH - *Microbiological Techniques MH - Relapsing Fever/diagnosis MH - Serologic Tests MH - Specimen Handling MH - Syphilis/diagnosis MH - Treponema pallidum/*isolation & purification MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 971024 DP - 1997 Jul IS - 0047-1860 TA - Rinsho Byori PG - 135-40 CY - JAPAN VI - Suppl 105 JC - KIV EM - 9801 RF - 4 PMID- 9379531 SO - Rinsho Byori 1997 Jul;Suppl 105:135-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97378831 AU - Ferreira Neto JS AU - Vasconcellos SA AU - Ito FH AU - Moretti AS AU - Camargo CA AU - Sakamoto SM AU - Marangon S AU - Turilli C AU - Martini M TI - Leptospira interrogans serovar icterohaemorrhagiae seropositivity and the reproductive performance of sows. LA - Eng MH - Aging/immunology/physiology MH - Animal MH - Animals, Newborn MH - Antibiotics/therapeutic use MH - Antibodies, Bacterial/*blood MH - Body Weight/physiology MH - Brazil/epidemiology MH - Breeding MH - Comparative Study MH - Female MH - Fetal Death/epidemiology/veterinary MH - Immunotherapy/methods/veterinary MH - Leptospira interrogans/*immunology MH - Male MH - Pregnancy MH - Reproduction/*physiology MH - Retrospective Studies MH - Risk Factors MH - Rodent Control MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/epidemiology/*physiopathology/therapy MH - Weil's Disease/physiopathology/therapy/*veterinary RN - 0 (Antibiotics) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 970903 DP - 1997 Jul IS - 0167-5877 TA - Prev Vet Med PG - 87-93 SB - M CY - NETHERLANDS IP - 1-2 VI - 31 JC - CWT AA - Author EM - 9711 AB - The reproductive performance of 28 sows seropositive to Leptospira interrogans serovar icterohaemorrhagiae was compared with that of 87 Leptospira sp. seronegative dams belonging to the same herd. Sows were sampled during 1988 to 1993. During this period the herd was not submitted to any kind of intervention (antibiotic therapy, immunoprophylaxis or rodent control). Relative risks (RR) of return to heat, mummified fetuses, stillbirth, and weak newborn piglets for infected sows were assessed and the differences in means of total piglets born per litter, piglets born alive, piglets effectively housed, weaned piglets, stillbirths, mummified fetuses, weak newborn piglets, weight at birth of the piglets effectively housed, weight at 21 days of life and weight at weaning were evaluated. Seropositive dams had a greater risk of having weak newborn piglets (RR = 1.67, 1.02 < or = CI 95% < or = 2.72) and also of having more weak newborn piglets per litter (P = 0.01). Other variables examined were not different (P > 0.05). AD - Departamento de Medicina Veterinaria Preventiva e Saude Animal, Faculdade de Medicina Veterinaria e Zootecnia, Universidade de Sao Paulo, Brazil. PMID- 9234428 SO - Prev Vet Med 1997 Jul;31(1-2):87-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 97365398 AU - Rathinam SR AU - Rathnam S AU - Selvaraj S AU - Dean D AU - Nozik RA AU - Namperumalsamy P TI - Uveitis associated with an epidemic outbreak of leptospirosis. LA - Eng MH - Adult MH - Aged MH - Antibiotics, Tetracycline/therapeutic use MH - Antibodies, Bacterial/analysis MH - Case Report MH - *Disease Outbreaks MH - Doxycycline/therapeutic use MH - Drug Administration Routes MH - Drug Therapy, Combination MH - Eye Infections, Bacterial/drug therapy/*etiology/pathology MH - Female MH - Glucocorticoids, Synthetic/therapeutic use MH - Human MH - India/epidemiology MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/diagnosis/drug therapy/*epidemiology MH - Male MH - Middle Age MH - Retrospective Studies MH - Uveitis/drug therapy/*microbiology/pathology MH - Visual Acuity RN - 0 (Antibiotics, Tetracycline) RN - 0 (Antibodies, Bacterial) RN - 0 (Glucocorticoids, Synthetic) RN - 564-25-0 (Doxycycline) PT - JOURNAL ARTICLE DA - 970804 DP - 1997 Jul IS - 0002-9394 TA - Am J Ophthalmol PG - 71-9 SB - A SB - M CY - UNITED STATES IP - 1 VI - 124 JC - 3OQ AA - Author EM - 9710 AB - PURPOSE: To define uveitis associated with leptospirosis in a clinical setting. METHODS: We present the clinical features of 73 consecutive cases of uveitis linked clinically to an outbreak of systemic leptospirosis in patients with antibodies to Leptospira species who were examined from January to September 1994. RESULTS: In 73 patients, the pattern of ocular involvement was unilateral in 35 and bilateral in 38. Panuveitis was seen in 106 eyes (95.5%), retinal periphlebitis in 57 eyes (51.4%), and hypopyon in 14 eyes (12.6%). Anterior uveitis alone without hypopyon was observed in three eyes (2.7%), whereas vitreous inflammatory reaction alone was seen in two eyes (1.8%). Sixty of 73 patients (82.2%) or 91 of 111 eyes (82.0%) were followed up for 8 months. Final visual acuity was 6/6 (20/20) in 47 eyes (52%) and improved during treatment, although not up to 6/6, in 15 eyes (16%). Twenty-eight eyes (31%) maintained same vision, and one eye showed deterioration of vision. CONCLUSION: Uveitis associated with leptospirosis may manifest as unilateral or bilateral uveitis, anterior uveitis, or panuveitis. The prognosis is generally good in this entity, even when the inflammation is severe. Awareness of this disease in endemic areas is important in order to differentiate it from other uveitic entities, especially in young male patients in whom other immunologic uveitides are also common. AD - Aravind Eye Hospital, Madurai, India. PMID- 9222235 SO - Am J Ophthalmol 1997 Jul;124(1):71-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97363842 AU - Mikaelian I AU - Higgins R AU - Lequient M AU - Major M AU - Lefebvre F AU - Martineau D TI - Leptospirosis in raccoons in Quebec: 2 case reports and seroprevalence in a recreational area. LA - Eng MH - Animal MH - Case Report MH - Female MH - Leptospira interrogans/isolation & purification MH - Nephritis, Interstitial/epidemiology/pathology/*veterinary MH - Pregnancy MH - Quebec/epidemiology MH - *Raccoons MH - Seroepidemiologic Methods MH - Support, Non-U.S. Gov't MH - Weil's Disease/epidemiology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 970909 DP - 1997 Jul IS - 0008-5286 TA - Can Vet J PG - 440-2 SB - M CY - CANADA IP - 7 VI - 38 JC - CLS AA - Author EM - 9711 AB - Raccoons may represent a source of leptospires for humans and domestic animals. We describe a case of severe interstitial nephritis associated with the serovar bratislava of Leptospira interrogans (1st report in wildlife), and the seroprevalence to 4 leptospire serovars in a recreational area in Quebec. AD - Centre Canadien Cooperatif de la Sante la Fraune, Saint-Hyacinthe (Quebec). PMID- 9220134 SO - Can Vet J 1997 Jul;38(7):440-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97355455 AU - Hay FS AU - Niezen JH AU - Miller C AU - Bateson L AU - Robertson H TI - Infestation of sheep dung by nematophagous fungi and implications for the control of free-living stages of gastro-intestinal nematodes. LA - Eng MH - Animal MH - Feces/*microbiology MH - Gastrointestinal System/parasitology MH - *Hyphomycetes/physiology MH - Nematoda/*microbiology MH - Nematode Infections/prevention & control/veterinary MH - New Zealand MH - Sheep/*parasitology MH - Sheep Diseases/prevention & control/*parasitology MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 970826 DP - 1997 Jul 1 IS - 0304-4017 TA - Vet Parasitol PG - 247-54 SB - M CY - NETHERLANDS IP - 4 VI - 70 JC - XBU AA - Author EM - 9710 AB - A field trial was conducted to assess the rate at which dung becomes infested by fungi which parasitise nematodes (nematophagous fungi) after deposition. Sheep dung was placed on field plots of bare ground, ryegrass (Lolium perenne), browntop (Agrostis capillaris) and white clover (Trifolium repens) in summer (February) and autumn (April), and subsamples were examined at intervals for the presence of nematophagous fungi. Nematophagous fungi occurred in 71% of 129 samples recovered in February and 57% of 58 samples recovered in April. Arthrobotrys oligospora, Monacrosporium candidum and Nematoctonus spp. were the most frequently isolated nematode-trapping fungi in both seasons. The endoparasitic nematophagous fungus Harposporium leptospira also occurred frequently in dung deposited in February, but not April. Fungi entered dung quickly, with 83% and 58% of dung samples containing nematophagous fungi at 3 days after deposition in February and April, respectively. The percentage of dung infested by nematophagous fungi on plots of bare ground, ryegrass, white clover and browntop was 76%, 75%, 61% and 55%, respectively. Results suggest that a number of species of nematophagous fungi are able to enter dung soon after deposition on a variety of types of ground cover. AD - AgResearch, Grasslands Research Centre, Palmerston North, New Zealand. PMID- 9211650 SO - Vet Parasitol 1997 Jul 1;70(4):247-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [2 protein links] [1 nucleotide link] [100 medline neighbors] UI - 97352700 AU - Bourhy P AU - Martel A AU - Margarita D AU - Saint Girons I AU - Belfaiza J TI - Homoserine O-acetyltransferase, involved in the Leptospira meyeri methionine biosynthetic pathway, is not feedback inhibited. LA - Eng MH - Acetyltransferases/*genetics/metabolism MH - Acyltransferases/genetics MH - Amino Acid Sequence MH - Bacterial Proteins/*genetics/metabolism MH - Base Sequence MH - Cloning, Molecular MH - DNA, Bacterial MH - Genetic Complementation Test MH - Leptospira/*enzymology/genetics MH - Methionine/*biosynthesis MH - Molecular Sequence Data MH - Operon MH - Sequence Homology, Amino Acid MH - Support, Non-U.S. Gov't RN - EC 2.3. (Acyltransferases) RN - EC 2.3.1. (Acetyltransferases) RN - EC 2.3.1.31 (homoserine acetyltransferase) RN - EC 2.3.1.46 (homoserine succinyltransferase) RN - 0 (Bacterial Proteins) RN - 0 (DNA, Bacterial) RN - 7005-18-7 (Methionine) PT - JOURNAL ARTICLE DA - 970819 DP - 1997 Jul IS - 0021-9193 TA - J Bacteriol PG - 4396-8 SB - M CY - UNITED STATES IP - 13 VI - 179 JC - HH3 AA - Author EM - 9710 AB - The Leptospira meyeri serovar semaranga metX gene was identified by complementation of an Escherichia coli metA mutant, i.e., devoid of homoserine O-succinyltransferase. However, the MetX protein exhibited a homoserine O-acetyltransferase activity in agreement with its similarity to homoserine O-acetyltransferases. Reverse transcription- PCR analysis demonstrated that metX is the second gene of an operon. AD - Unite de Bacteriologie Moleculaire et Mf1edicale, Institut Pasteur, Paris, France. PMID- 9209059 SI - GENBANK/Y10744 SO - J Bacteriol 1997 Jul;179(13):4396-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97357216 TI - Outbreak of leptospirosis among white-water rafters--Costa Rica, 1996. LA - Eng MH - Adult MH - Costa Rica/epidemiology MH - *Disease Outbreaks MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology MH - *Recreation MH - Travel MH - United States/epidemiology MH - Water RN - 7732-18-5 (Water) PT - JOURNAL ARTICLE DA - 970715 DP - 1997 Jun 27 IS - 0149-2195 TA - MMWR Morb Mortal Wkly Rep PG - 577-9 SB - M CY - UNITED STATES IP - 25 VI - 46 JC - NE8 AA - Author EM - 9709 AB - On October 15, 1996, a physician notified the Illinois Department of Public Health about five patients with an unknown febrile illness who had returned from a white-water rafting trip on flooded rivers in Costa Rica during September 27-28, 1996. The five patients had been members of a white-water rafting expedition involving 26 rafters from five states, the District of Columbia, and Costa Rica. This report summarizes the findings of the multistate investigation conducted by the Illinois Department of Public Health and by CDC in collaboration with the Ministry of Health of Costa Rica. The findings implicated leptospirosis as the cause of disease and contaminated river water as the probable source of illness. PMID- 9214567 NI - A SO - MMWR Morb Mortal Wkly Rep 1997 Jun 27;46(25):577-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97380824 AU - Sleth JC AU - Rodier V AU - Andre E AU - Knoerr MF TI - [Pseudo-pancreatitis in L. icterohaemorrhagiae leptospirosis (letter)] LA - Fre MH - Aged MH - Case Report MH - Diagnosis, Differential MH - Human MH - Male MH - Pancreatitis/diagnosis MH - Weil's Disease/*complications PT - LETTER DA - 970805 DP - 1997 Jun 14 IS - 0755-4982 TA - Presse Med PG - 955 SB - M SB - X CY - FRANCE IP - 20 VI - 26 JC - PMT EM - 9710 PMID- 9238181 TT - Pseudopancreatite au cours d'une leptospirose a L icterohaemorrhagiae. SO - Presse Med 1997 Jun 14;26(20):955 ---------------------------------------------------------------------------- Other Formats: [Citation Format] UI - 97412305 AU - Benito Calavia JR AU - Montejo Baranda M AU - Pumarola T AU - Perez Irezabal J AU - Aguirrebengoa Ibarguren K AU - Gonzalez Ortiz de Zarate P AU - Barreiro Garcia G AU - Aguirre Errasti C TI - [Leptospirosis. Review of 11 cases] LA - Spa MH - Adult MH - English Abstract MH - Hematuria/etiology MH - Human MH - Jaundice/etiology MH - Leptospira/classification/isolation & purification MH - Leptospirosis/complications/*epidemiology/microbiology/pathology MH - Male MH - Middle Age MH - Multiple Organ Failure/etiology MH - Myocardial Diseases/etiology MH - Occupational Diseases/epidemiology/microbiology MH - Retrospective Studies MH - Spain/epidemiology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, MULTICASE DA - 971124 DP - 1997 Jun-Jul IS - 0213-005X TA - Enferm Infecc Microbiol Clin PG - 306-9 CY - SPAIN IP - 6 VI - 15 JC - A10 AA - Author EM - 9801 AB - Eleven cases of leptospirosis diagnosed from 1988 to 1994 were retrospectively reviewed. The mean age of the patients was 52 years. Epidemiologic factors were found in 10 patients. Hepatorenal involvement was observed in 7 cases (64%), cardiac involvement in 3 (27%), bleeding episodes in 5 (45%) and central nervous system involvement in one case (9%). The Leptospira serogroups identified were: Icterohaemorrhage in 6 cases, Pomona in 1, Sejroe in and could not be determined in 3. One patient died because of multiorgan failure. The epidemiologic, clinical, analytical and therapeutic aspects are discussed. AD - Unidad de Enfermedades Infecciosas-Medicina Interna, Hospital Clinic i Provincial, Barcelona. RF - 23 PMID- 9376401 TT - Leptospirosis: Revision de 11 casos. EA - A SO - Enferm Infecc Microbiol Clin 1997 Jun-Jul;15(6):306-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97384121 AU - Busato A AU - Steiner L AU - Gottstein B AU - Gaillard C TI - [Frequency and etiology of calf losses and calf diseases in cow-calf farms. III. seroprevalence of selected diseases and prevalence of endoparasites and weaning age] LA - Ger MH - Aging MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Cross-Sectional Studies MH - English Abstract MH - Female MH - Gastrointestinal Diseases/epidemiology/parasitology/*veterinary MH - Germany/epidemiology MH - Helminthiasis/epidemiology/veterinary MH - Larva MH - Ovum MH - Parasitic Diseases/epidemiology/*veterinary MH - Protozoan Infections/epidemiology/veterinary MH - Support, Non-U.S. Gov't MH - Weaning PT - JOURNAL ARTICLE DA - 970922 DP - 1997 Jun IS - 0341-6593 TA - DTW Dtsch Tierarztl Wochenschr PG - 191-5 CY - GERMANY IP - 6 VI - 104 JC - ECT AA - Author EM - 9711 AB - In a cross sectional study in 38 cow-calf farms blood and fecal samples were taken from 207 calves at an age of 8-10 months and their darms, in order to determine the seroprevalence of Leptospira hardjo, Coxiella burnetii, Toxoplasma gondii and the presence of the BVD-Antigen as well as the prevalence of endoparasites. The study was conducted in fall 1994 at the end of the grazing period. Eggs or larvaes of gastrointestinal helminths were detected in 74% of calves that were dewormed before the grazing period and in 88% of untreated calves. The difference between the two groups was statistically significant. In 83% of the weaned calves oocysts of Eimeria spp. were diagnosed. No significant difference in weight gain was observed between animals without endoparasites and animals infected with either helminths and/or Eimeria. In cows the prevalence was 61.5% for helminths and 45.7% for Eimeria spp. In calves the seroprevalence was 4% for Leptospira hardjo, 0.5% for Coxiella burnetii and 14.0% for Toxoplasma gondii. The seroprevalence in cows were 18% for Leptospira hardjo, 7.6% for Coxiella burnetii and 14.3% for Toxoplasma gondii. The prevalence of the BVD-Virus antigen was 0.5% for calves and cows. AD - Institut fur Tierzucht, Veterinarmedizinischen Fakultat, Universitat Bern. PMID- 9303850 TT - Haufigkeiten und Ursachen von Kalberverlusten und Kalberkrankheiten in Mutterkuhbetrieben. III. Seropravalenz ausgewahlter Krankheiten und Pravalenz von Endoparasiten beim Absetzen. EA - A SO - DTW Dtsch Tierarztl Wochenschr 1997 Jun;104(6):191-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97403181 AU - Collares-Pereira M AU - Korver H AU - Terpstra WJ AU - Santos-Reis M AU - Ramalhinho MG AU - Mathias ML AU - Oom MM AU - Fons R AU - Libois R AU - Petrucci-Fonseca F TI - First epidemiological data on pathogenic leptospires isolated on the Azorean islands. LA - Eng MH - Animal MH - Azores MH - Disease Vectors MH - Female MH - Insectivora/*microbiology MH - Kidney/microbiology MH - Leptospira/*classification MH - Leptospirosis/*microbiology/*veterinary MH - Male MH - Mice/*microbiology MH - Prevalence MH - Rats/*microbiology MH - Serotyping MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 970925 DP - 1997 Jun IS - 0392-2990 TA - Eur J Epidemiol PG - 435-41 SB - M CY - NETHERLANDS IP - 4 VI - 13 JC - ERE AA - Author EM - 9711 AB - Insectivores (Erinaceus europaeus) and rodents (Rattus rattus, R. norvegicus and Mus musculus) from different islands of the Azores Archipelago were found to carry three distinct Leptospira interrogans s.l. serovars (copenhageni, icterohaemorrhagiae and ballum) which have never been previously investigated there. The house mouse and the black rat were the major Leptospira reservoirs showing isolation rates ranging from 0% for both species (in Graciosa) to 88% and 33%, respectively (in Saao Miguel). This study also showed that the majority of the animals with positive kidney cultures exhibited specific agglutinins against the isolated strains of Leptospira. The observed isolation rates in the different islands, with a very interesting island variation in prevalence, suggest that small mammals, serving as sylvatic reservoirs of pathogenic leptospires, may represent an important risk to the health of humans and livestock, particularly in the islands of Terceira and Saao Miguel. AD - Laboratorio de Leptospiras, Universidade Nova de Lisboa, Portugal. cmdt@esoterica.pt PMID- 9258550 SO - Eur J Epidemiol 1997 Jun;13(4):435-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 97374349 AU - da Silva MV AU - Nakamura PM AU - Camargo ED AU - Batista L AU - Vaz AJ AU - Romero EC AU - Brandao AP TI - Immunodiagnosis of human leptospirosis by dot-ELISA for the detection of IgM, IgG, and IgA antibodies. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Antibodies, Bacterial/blood MH - Child MH - Cross-Sectional Studies MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Human MH - IgA/*blood MH - IgG/*blood MH - IgM/*blood MH - Leptospira interrogans/*immunology MH - Leptospirosis/*diagnosis/immunology MH - Male MH - Middle Age RN - 0 (Antibodies, Bacterial) RN - 0 (IgA) RN - 0 (IgG) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 970813 DP - 1997 Jun IS - 0002-9637 TA - Am J Trop Med Hyg PG - 650-5 SB - A SB - M CY - UNITED STATES IP - 6 VI - 56 JC - 3ZQ AA - Author EM - 9710 AB - A dot-ELISA was evaluated using antigen obtained from Leptospira interrogans cultures of the serovars brasiliensis, canicola, cynopteri, hebdomadis, and icterohaemorrhagiae for the detection of human IgM, IgG, and IgA. Single serum samples from 63 patients with the icterohemorrhagic form of leptospirosis in the acute phase, collected 3- 14 days (mean = 7 days) after the onset of symptoms were tested. Ten patients were examined during convalescence and followed up for a period of 4-12 months. For a control group, serum samples from 10 apparently healthy individuals with no clinical or epidemiologic history of leptospirosis, and from 38 patients with nonleptospiral illnesses were used. In the acute phase, IgM antibodies were detected in 62 (98%) of 63 patients and IgG and IgA were observed in 70% and 76% of them, respectively. For the admission serum samples, the predictive value negative of the dot-ELISA was 98% for IgM, 72% for IgG, and 76% for IgA detection. All 10 patients followed-up during convalescence showed IgM antibodies up to the sixth month, decreasing to 57% by the 10th month, and persisting in only one of six patients during the 11th and 12th months of follow-up. Immunoglobulin G was detected in six patients up to the fourth month and in two of six individuals up to the end of follow-up. Immunoglobulin A was observed in all patients up to the end of the first month, decreasing progressively up to the sixth month, and was no longer detected in any patients from seventh to the 12th months of follow-up. The dot-ELISA can be used as an important laboratory screening test, especially when detecting IgM antibodies. It proved to be effective in the diagnosis of human leptospirosis, and appears to have advantages in terms of yield, time, and case of execution and low cost. AD - Emilio Ribas Infectology Institute, Sao Paulo, Brazil. PMID- 9230798 SO - Am J Trop Med Hyg 1997 Jun;56(6):650-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 97323161 AU - Hudson CP AU - Levett PN AU - Edwards CN AU - Moosai R AU - Roach TC TI - Severe primary HIV-1 infection among black persons in Barbados. LA - Eng MH - Barbados/epidemiology MH - HIV Antibodies/blood MH - HIV Infections/diagnosis/*epidemiology/immunology/physiopathology MH - *HIV-1/immunology/isolation & purification MH - *Negroid Race RN - 0 (HIV Antibodies) PT - JOURNAL ARTICLE DA - 970729 DP - 1997 Jun IS - 0956-4624 TA - Int J STD AIDS PG - 393-7 SB - M CY - ENGLAND IP - 6 VI - 8 JC - A16 AA - Author EM - 9710 AB - Descriptions of primary HIV-1 infection have so far been based on Caucasians living in industrialized nations. Due to studies of leptospirosis in the predominantly black population of Barbados, serum was available for patients admitted with acute febrile illnesses to the Queen Elizabeth Hospital (QEH). By searching the medical records of 510 adult patients with known HIV-1 infection we identified 10 patients who had stored serum from an admission for an acute febrile illness that predated or coincided with their first HIV-1-positive test. Serological testing confirmed primary HIV-1 infection in 9 and was suggestive in the 10th patient. The clinical features of these 10 patients were in keeping with previous descriptions of primary HIV-1 infection but differed from leptospirosis cases seen at the QEH. One patient died during his seroconversion illness and another died 3 months after seroconversion. The findings suggest that severe primary HIV-1 infection could be a relatively uncommon occurrence, that the condition may be misdiagnosed, and that cases may not occur until the AIDS epidemic is established. AD - Department of Medicine, University of the West Indies, Queen Elizabeth Hospital, Barbados. PMID- 9179651 SO - Int J STD AIDS 1997 Jun;8(6):393-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] UI - 97446719 AU - Matiash VI AU - Anisimova IuN TI - [The clinico-morphological characteristics of the nervous system lesions in icterohemorrhagic leptospirosis] LA - Rus MH - Acute Disease MH - Adolescence MH - Adult MH - Brain/pathology MH - Central Nervous System Diseases/cerebrospinal fluid/diagnosis/etiology/*pathology MH - English Abstract MH - Human MH - Meninges/pathology MH - Middle Age MH - Time Factors MH - Weil's Disease/cerebrospinal fluid/complications/diagnosis/*pathology PT - JOURNAL ARTICLE DA - 971106 DP - 1997 May-Jun IS - 1019-5297 TA - Lik Sprava PG - 94-9 CY - UKRAINE IP - 3 JC - CIU AA - Author EM - 9801 AB - A total of 120 patients were examined presenting with a grave course of icterohemorrhagic leptospirosis; a pathomorphologic investigation of the brain from 75 deceased was done. Practically in all cases, the affection was accompanied by neurotoxicosis, with microcirculatory disturbances being its morphological substrate. The leading clinical syndromes of the affection of the central nervous system appeared to be general cerebral, meningeal, and encephalitic syndromes. Meningitis was diagnosed in 29.2%, meningoencephalitis in 5% of patients. Morphologic studies showed that predominantly focal serous meningitides and meningoencephalitides are significantly more common that they are diagnosed in clinical settings. They tend to develop during the second and third weeks of the course of the illness. Lumbal puncture is to be carried out on a differentiated basis only, since it may cause dysbalance in metabolic processes of the organism together with progression of those events being related to brain swelling. PMID- 9377366 TT - Kliniko-morfologicheskaia kharakteristika porazhenii nervnoi sistemy pri ikterogemorragicheskom leptospiroze. EA - A SO - Lik Sprava 1997 May-Jun;(3):94-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97333668 AU - Hecker K AU - Groll J AU - Muller-Lissner S TI - [Acute renal failure, jaundice and thrombocytopenia in a 48-year-old patient] LA - Ger MH - Bilirubin/blood MH - Case Report MH - Creatinine/blood MH - Diagnosis, Differential MH - Dose-Response Relationship, Drug MH - Drug Administration Schedule MH - Human MH - Jaundice/drug therapy/*etiology MH - Kidney Failure, Acute/drug therapy/*etiology MH - Leptospirosis/blood/*diagnosis/drug therapy MH - Male MH - Middle Age MH - Penicillin G/administration & dosage MH - Platelet Count/drug effects MH - Thrombocytopenia/drug therapy/*etiology MH - Water Microbiology RN - 60-27-5 (Creatinine) RN - 61-33-6 (Penicillin G) RN - 635-65-4 (Bilirubin) PT - JOURNAL ARTICLE DA - 970821 DP - 1997 May IS - 0020-9554 TA - Internist (Berl) PG - 470-3 SB - M CY - GERMANY IP - 5 VI - 38 JC - GVX EM - 9710 AD - Abteilung Innere Medizin, Krankenhaus Weissensee, Berlin. PMID- 9264985 TT - Akutes Nierenversagen, Ikterus und Thrombozytopenie bei einem 48jahrigen Patienten. SO - Internist (Berl) 1997 May;38(5):470-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97372462 AU - Taylor MJ AU - Ellis WA AU - Montgomery JM AU - Yan KT AU - McDowell SW AU - Mackie DP TI - Magnetic immuno capture PCR assay (MIPA): detection of Leptospira borgpetersenii serovar hardjo. LA - Eng MH - Animal MH - Antibodies, Monoclonal/diagnostic use MH - Cattle MH - Cells, Cultured MH - Comparative Study MH - Female MH - Leptospira/*isolation & purification MH - Leptospirosis/*microbiology/urine MH - Male MH - Polymerase Chain Reaction/*methods MH - Sensitivity and Specificity RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 970815 DP - 1997 May IS - 0378-1135 TA - Vet Microbiol PG - 135-45 SB - M CY - NETHERLANDS IP - 1-2 VI - 56 JC - XBW AA - Author EM - 9710 AB - Magnetic immuno PCR assay (MIPA) was developed for the rapid detection of leptospires excreted in urine samples (n = 59) collected from 35 experimentally infected cattle. The immunomagnetic separation of leptospires from inhibitors in frozen formalin fixed bovine urine prior to PCR detection resulted in a marked improvement on previous detection methods. MIPA is a rapid 5 step protocol requiring 70 mins preparation time prior to amplification, which consistently detects 10(1) organisms. MIPA detected 76% (38/50) of culture positive urines and in addition three urines that were culture negative were shown to be positive by this method of detection. Consequently we conclude that whilst MIPA is an improvement on previously published PCR detection methods, the culture of the organism is still the standard against which other detection methods have to be compared. AD - Department of Agriculture for Northern Ireland, Veterinary Sciences Division, Belfast, UK. PMID- 9228689 SO - Vet Microbiol 1997 May;56(1-2):135-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [2 nucleotide links] [108 medline neighbors] UI - 97306633 AU - Woo TH AU - Smythe LD AU - Symonds ML AU - Norris MA AU - Dohnt MF AU - Patel BK TI - Rapid distinction between Leptospira interrogans and Leptospira biflexa by PCR amplification of 23S ribosomal DNA. LA - Eng MH - Base Sequence MH - Comparative Study MH - DNA Primers MH - DNA, Bacterial/*genetics MH - Leptospira/*genetics/pathogenicity MH - Leptospira interrogans/*genetics/pathogenicity MH - Molecular Sequence Data MH - Polymerase Chain Reaction/*methods MH - RNA, Ribosomal, 16S/genetics MH - RNA, Ribosomal, 23S/*genetics MH - Sequence Analysis, DNA MH - Sequence Homology, Amino Acid MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) RN - 0 (RNA, Ribosomal, 16S) RN - 0 (RNA, Ribosomal, 23S) PT - JOURNAL ARTICLE DA - 970623 DP - 1997 May 1 IS - 0378-1097 TA - FEMS Microbiol Lett PG - 9-18 SB - M CY - NETHERLANDS IP - 1 VI - 150 JC - FML AA - Author EM - 9708 AB - Bacterial specific primers were used to amplify 23S rRNA genes from a representative strain from each of the 23 serogroups of the pathogenic Leptospira interrogans and 8 strains from 6 serogroups of the non- pathogenic Leptospira biflexa. Only regions of extreme variability, which had been identified on the basis of homology-based search of all the 23S rRNA sequences available in GenBank database, were sequenced from the amplified products. PCR primers that had the potential to distinguish L. interrogans from L. biflexa species were designed from the derived sequences and a sensitive PCR protocol developed. The PCR method enabled the differentiation of the 59 strains of the 23 serogroups of L. interrogans from the 8 strains of 6 serogroups of L. biflexa. Further investigation by 16S rDNA sequencing of two strains of L. interrogans, which gave unexpected PCR results, provided evidence that they had been misclassified and hence we propose to reassign them to L. biflexa. AD - School of Biomolecular and Biomedical Sciences, Faculty of Science and Technology, Griffith University, Nathan, Brisbane, QLD, Australia. PMID- 9163900 SI - GENBANK/U80038 SI - GENBANK/U80039 SI - GENBANK/Z26969 SI - GENBANK/Z12821 SI - GENBANK/M88721 SI - GENBANK/Z21638 SI - GENBANK/U12676 SI - GENBANK/U12673 SI - GENBANK/U12677 SI - GENBANK/X17547 SI - GENBANK/J01695 SO - FEMS Microbiol Lett 1997 May 1;150(1):9-18 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 97295835 AU - Akhtar S AU - Farver TB AU - Riemann HP TI - A sero-epidemiological study of Haemophilus somnus infection in dairy cattle. LA - Eng MH - Animal MH - California MH - Cattle MH - Cattle Diseases/epidemiology/*microbiology MH - Female MH - Haemophilus MH - Haemophilus Infections/epidemiology/*veterinary MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 970707 DP - 1997 May IS - 0165-7380 TA - Vet Res Commun PG - 229-39 SB - M CY - NETHERLANDS IP - 4 VI - 21 JC - XCD AA - Author EM - 9709 AB - Five repeated cross-sectional serological surveys of 790 dairy cattle in 4 dairy herds between December 1985 and February 1987 provided an opportunity to study the changes in the seroprevalence of Haemophilus somnus across the 5 surveys and with respect to some demographic and disease variables. The demographic variables included were age (heifers or cows) and farm, representing two groups of herds (two herds in each group, located in the Central and Northern Valleys of California). The serological status of cattle as either negative or positive against H. somnus, Campylobacter fetus and Leptospira hardjo were determined with enzyme linked-immunosorbent assays. Logistic regression analysis was used to compute maximum likelihood estimates of adjusted odds ratios and their respective 95% confidence intervals. The baseline risk of being H. somnus seropositive in the cattle observed at first sampling did not vary significantly during the study period after adjustment for the effects of covariates. Only at first sampling were cows about twice as likely to be H. somnus seropositive than heifers. At samplings 1 and 3, but not at 2 and 5, being in the herds of the Central Valley appeared protective. In contrast, at sampling 4 the cattle in herds in the Central Valley were about 7 times more likely to be H. somnus seropositive. C. fetus-positive cattle were about 3 times more likely to be H. somnus seropositive at sampling 1 only. The relationship between H. somnus status and L. hardjo was not significant during the study period. AD - Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis 95616, USA. PMID- 9151407 SO - Vet Res Commun 1997 May;21(4):229-39 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [98 medline neighbors] UI - 97348257 AU - Meslin FX TI - Global aspects of emerging and potential zoonoses: a WHO perspective. LA - Eng MH - Animal MH - Cattle MH - Escherichia coli Infections/etiology MH - Human MH - Leptospirosis/etiology MH - Rabies/etiology MH - Salmonella Infections/etiology MH - World Health Organization MH - Zoonoses/*etiology PT - JOURNAL ARTICLE DA - 970724 DP - 1997 Apr-Jun IS - 1080-6040 TA - Emerg Infect Dis PG - 223-8 SB - M CY - UNITED STATES IP - 2 VI - 3 JC - COD AA - Author EM - 9709 AB - Many new human pathogens that have emerged or reemerged worldwide originated from animals or from products of animal origin. Many animal species as well as categories of agents have been involved in the emergence of diseases. Wild (e.g., bats, rodents) as well as draught animals (e.g., horses) and food animals (e.g., poultry, cattle) were implicated in the epidemiologic cycles of these diseases. Many of the agents responsible for new infections and diseases in humans were viruses (e.g., hantaviruses, lyssaviruses, and morbilliviruses), but bacteria, especially enteritic bacteria (e.g., Salmonellae and Escherichia coli) and parasites (e.g., Cryptosporidium) of animal origin, were also involved in major food and waterborne outbreaks. The public health relevance of some of these agents (e.g., new lyssaviruses and morbilliviruses) is not yet fully assessed. In addition the zoonotic nature of some other human diseases, such as Ebola and the new variant form of Creutzfeldt-Jakob disease, is suspected but not yet demonstrated. Finally, the possible future use of xenografts may lead, if precautions are not taken, to the emergence of new diseases called xenozoonoses. AD - Division of Emerging and Other Communicable Diseases--Surveillance and Control, World Health Organization, Geneva, Switzerland. PMID- 9204308 SO - Emerg Infect Dis 1997 Apr-Jun;3(2):223-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97278230 AU - Taylor SK AU - Lane VM AU - Hunter DL AU - Eyre KG AU - Kaufman S AU - Frye S AU - Johnson MR TI - Serologic survey for infectious pathogenes in free-ranging American bison [In Process Citation] LA - Eng DA - 970506 DP - 1997 Apr IS - 0090-3558 TA - J Wildl Dis PG - 308-11 SB - M CY - UNITED STATES IP - 2 VI - 33 JC - KEM AA - AUTHOR AB - From November 1991 through March 1992, we evaluated 101 free-ranging American bison (Bison bison) from Yellowstone National Park, Wyoming (USA) for exposure to infectious organisms that commonly infect cattle. No titers were detected for bluetongue virus, bovine leukemia virus, or Campylobacter fetus in these 101 bison. Detectable antibodies occurred against Anaplasma marginale (eight of 76, 11%), bovine respiratory syncytial virus (31 of 101, 31%), bovine viral diarrhea (31 of 101, 31%), bovine herpesvirus 1 (29 of 76, 38%), Leptospira interrogans icterohaemorrhagiae (four of 101, 4%), L interrogans hardjo (seven of 101, 7%), L interrogans autumnalis (one of 101, 1%), L interrogans bratislava (seven of 101, 7%), L interrogans australis (one of 101, 1%), and parainfluenza 3 virus (27 of 75, 36%). The low antibody titers and the lack of gross lesions are evidence that while previous exposure to infectious organisms may have occurred, none appeared to have active infections. AD - National Park Service, Wildlife and Vegetation Division, Washington, D.C. 20013, USA. RO - O:099 PMID- 9131564 SO - J Wildl Dis 1997 Apr;33(2):308-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 97278221 AU - Day TD AU - Waas JR AU - O'Connor CE AU - Carey PW AU - Matthews LR AU - Pearson AJ TI - Leptospirosis in brushtail possums: is Leptospira interrogans serovar balcanica environmentally transmitted? [In Process Citation] LA - Eng DA - 970506 DP - 1997 Apr IS - 0090-3558 TA - J Wildl Dis PG - 254-60 SB - M CY - UNITED STATES IP - 2 VI - 33 JC - KEM AA - AUTHOR AB - In New Zealand, the biological control of introduced brushtail possums (Trichosurus vulpecula) may be the only affordable option for achieving a significant long term reduction in pest numbers on a national scale. Leptospira interrogans serovar balcanica is among the potential biocontrol agents and vectors currently being investigated for this purpose. As the transmission pathways of L. interrogans serovar balcanica between possums are poorly understood, the objective of the study was to determine whether infection could result from exposure to contaminated environments. Sixteen individually housed, uninfected possums, in three groups, were regularly exposed over a period of 32 days to contaminated cages or grass enclosures of 16 other experimentally infected possums all shedding leptospires in their urine. None of the 16 challenged possums developed serological evidence of L. interrogans serovar balcancia infection. These results suggest that this organism is unlikely to be transmitted environmentally, supporting previous circumstantial evidence that social contact may be required for transmission of L. interrogans serovar balcanica between possums. AD - Department of Biological Sciences, University of Waikato, Hamilton, New Zealand. RO - O:099 PMID- 9131555 SO - J Wildl Dis 1997 Apr;33(2):254-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [98 medline neighbors] UI - 97230340 AU - Burth P AU - Younes-Ibrahim M AU - Goncalez FH AU - Costa ER AU - Faria MV TI - Purification and characterization of a Na+, K+ ATPase inhibitor found in an endotoxin of Leptospira interrogans. LA - Eng MH - Endotoxins/*metabolism MH - Enzyme Inhibitors/*isolation & purification/metabolism MH - Leptospira interrogans/*metabolism MH - Na(+)-K(+)-Exchanging ATPase/*antagonists & inhibitors MH - Support, Non-U.S. Gov't RN - EC 3.6.1.37 (Na(+)-K(+)-Exchanging ATPase) RN - 0 (Endotoxins) RN - 0 (Enzyme Inhibitors) PT - JOURNAL ARTICLE DA - 970424 DP - 1997 Apr IS - 0019-9567 TA - Infect Immun PG - 1557-60 SB - M SB - X CY - UNITED STATES IP - 4 VI - 65 JC - GO7 AA - Author EM - 9706 AB - We showed previously that the glycolipoprotein fraction prepared from Leptospira interrogans inhibited the Na+,K+ ATPase enzyme purified from brain or kidney and in isolated nephron segments (M. Younes-Ibrahim, P. Burth, M. V. Castro Faria, B. Buffin-Meyer, S. Marsy, C. Barlet-Bas, L. Cheval, and A. Doucet, C. R. Acad. Sci. Paris Ser. III 318:619-625, 1995). In the present communication, we have demonstrated that unsaturated fatty acids such as oleic and palmitoleic acids, which are adsorbed to this fraction, are effective inhibitors of the enzyme. AD - Departamento de Biologia Celular e Genetica, Instituto de Biologia, Universidade do Estado do Rio de Janeiro, Brazil. PMID- 9119504 SO - Infect Immun 1997 Apr;65(4):1557-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 97256949 AU - Ramadass P AU - Meerarani S AU - Venkatesha MD AU - Senthilkumar A AU - Nachimuthu K TI - Characterization of leptospiral serovars by randomly amplified polymorphic DNA fingerprinting. LA - Eng MH - Base Sequence MH - Comparative Study MH - DNA Fingerprinting/*methods/statistics & numerical data MH - DNA Primers/genetics MH - DNA, Bacterial/*genetics/isolation & purification MH - Leptospira/*classification/*genetics MH - Random Amplified Polymorphic DNA Technique/statistics & numerical data MH - Sensitivity and Specificity MH - Serotyping MH - Species Specificity RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 970603 DP - 1997 Apr IS - 0020-7713 TA - Int J Syst Bacteriol PG - 575-6 SB - M CY - UNITED STATES IP - 2 VI - 47 JC - AWO AA - Author EM - 9708 AB - Randomly amplified polymorphic DNA (RAPD) fingerprinting of 14 laboratory strains of leptospiral serovars (serovars australis, autumnalis, ballum, bataviae, canicola, grippotyphosa, hardjoprajitno, hebdomadis, icterohaemorrhagiae, javanica, pomona, pyrogenes, panama, and tarassovi) was carried out by using a pair of primers. Each serovar had a unique and distinct fingerprint pattern. DNAs of other bacterial species, including Escherichia coli, Pasteurella multocida, Salmonella spp., Pseudomonas spp., and Klebsiella spp., did not show any amplification. RAPD fingerprinting was found to be a rapid and sensitive method for serovar identification when it was compared to DNA restriction enzyme analysis, which produced a larger number of bands that made it more difficult to compare serovars. AD - Department of Animal Biotechnology, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu, India. PMID- 9103653 SO - Int J Syst Bacteriol 1997 Apr;47(2):575-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97245286 AU - West HJ TI - Clinical and pathological studies in cattle with hepatic disease. LA - Eng MH - gamma-Glutamyltransferase/blood MH - Ammonia/blood MH - Animal MH - Bile Acids and Salts/blood MH - Biopsy/methods/veterinary MH - Blood Glucose/analysis/metabolism MH - Cattle MH - Cattle Diseases/*blood/diagnosis/*pathology MH - Female MH - Glutamate Dehydrogenase/blood MH - Ketone Bodies/blood MH - Leucine/blood MH - Liver/*pathology MH - Liver Diseases/blood/pathology/*veterinary MH - Nucleosidases/blood MH - Prognosis MH - Urea/blood RN - EC 1.4.1.2 (Glutamate Dehydrogenase) RN - EC 2.3.2.2 (gamma-Glutamyltransferase) RN - EC 3.2.2. (Nucleosidases) RN - 0 (Bile Acids and Salts) RN - 0 (Blood Glucose) RN - 0 (Ketone Bodies) RN - 57-13-6 (Urea) RN - 7005-03-0 (Leucine) RN - 7664-41-7 (Ammonia) PT - JOURNAL ARTICLE DA - 970619 DP - 1997 Apr IS - 0165-7380 TA - Vet Res Commun PG - 169-85 SB - M CY - NETHERLANDS IP - 3 VI - 21 JC - XCD AA - Author EM - 9708 AB - In cattle with hepatic lipidosis, hepatic abscessation, leptospirosis, biliary calculi or fasciolosis, the progression of the disease was studied by serial measurements of serum total bile acid concentrations, plasma glutamate dehydrogenase, gamma-glutamyltransferase, 5'- nucleotidase and leucine aminopeptidase activities Terminalia avicennioides and by liver biopsy. Regardless of the cause of the hepatic disease, weight loss, anorexia, dullness and depression were consistent features. Signs of hepatic encephalopathy, such as blindness, head pressing, excitability, ataxia and weakness were less common and, together with pyrexia and jaundice, were grave prognostic signs. Plasma ammonia concentrations were significantly elevated compared to clinically normal cattle, but such changes were not always accompanied by a decline in plasma urea concentrations. In normal, healthy cattle, the plasma ammonia:urea concentration ratio is 9:1 and the plasma ammonia:glucose concentration is 11:1. In hepatic disease, a plasma ammonia:glucose ratio > 40:1 or plasma ammonia:urea ratio > 30:1, particularly with a rising total ketone body concentration and a declining glucose concentration, carried a guarded prognosis. The study suggested that other factors, such as hypokalaemia, alkalosis, short- chain volatile fatty acids, and false and true neuro-transmitters, may be important in the pathogenesis of hepatic coma in cattle. AD - Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool Veterinary Field Station, Neston, South Wirral, UK. PMID- 9090045 SO - Vet Res Commun 1997 Apr;21(3):169-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 protein link] [1 nucleotide link] [100 medline neighbors] UI - 97234635 AU - Shang ES AU - Skare JT AU - Erdjument-Bromage H AU - Blanco DR AU - Tempst P AU - Miller JN AU - Lovett MA TI - Sequence analysis and characterization of a 40-kilodalton Borrelia hermsii glycerophosphodiester phosphodiesterase homolog. LA - Eng MH - Amino Acid Sequence MH - Antigens, Bacterial/genetics MH - Bacterial Outer Membrane Proteins/genetics MH - Base Sequence MH - Borrelia/*enzymology/genetics MH - Cell Compartmentation MH - Cloning, Molecular MH - Cross Reactions MH - DNA, Bacterial/genetics MH - Electrophoresis, Gel, Two-Dimensional MH - Escherichia coli/enzymology MH - Genes, Structural, Bacterial MH - Haemophilus influenzae/enzymology MH - Molecular Sequence Data MH - Phosphoric Diester Hydrolases/chemistry/*genetics MH - Sequence Alignment MH - Sequence Homology, Amino Acid MH - Species Specificity MH - Support, U.S. Gov't, P.H.S. RN - EC 3.1.4 (Phosphoric Diester Hydrolases) RN - EC 3.1.4.46 (glycerophosphodiester phosphodiesterase) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE ID - AI-21352/AI/NIAID ID - AI-29733/AI/NIAID ID - AI-37312/AI/NIAID ID - + DA - 970429 DP - 1997 Apr IS - 0021-9193 TA - J Bacteriol PG - 2238-46 SB - M CY - UNITED STATES IP - 7 VI - 179 JC - HH3 AA - Author EM - 9707 AB - We report the purification, molecular cloning, and characterization of a 40-kDa glycerophosphodiester phosphodiesterase homolog from Borrelia hermsii. The 40-kDa protein was solubilized from whole organisms with 0.1% Triton X-100, phase partitioned into the Triton X-114 detergent phase, and purified by fast-performance liquid chromatography (FPLC). The gene encoding the 40-kDa protein was cloned from a B. hermsii chromosomal DNA lambda EXlox expression library and identified by using affinity antibodies generated against the purified native protein. The deduced amino acid sequence included a 20-amino-acid signal peptide encoding a putative leader peptidase II cleavage site, indicating that the 40-kDa protein was a lipoprotein. Based on significant homology (31 to 52% identity) of the 40-kDa protein to glycerophosphodiester phosphodiesterases of Escherichia coli (GlpQ), Bacillus subtilis (GlpQ), and Haemophilus influenzae (Hpd; protein D), we have designated this B. hermsii 40-kDa lipoprotein a glycerophosphodiester phosphodiesterase (Gpd) homolog, the first B. hermsii lipoprotein to have a putative functional assignment. A nonlipidated form of the Gpd homolog was overproduced as a fusion protein in E. coli BL21(DE3)(pLysE) and was used to immunize rabbits to generate specific antiserum. Immunoblot analysis with anti-Gpd serum recognized recombinant H. influenzae protein D, and conversely, antiserum to H. influenzae protein D recognized recombinant B. hermsii Gpd (rGpd), indicating antigenic conservation between these proteins. Antiserum to rGpd also identified native Gpd as a constituent of purified outer membrane vesicles prepared from B. hermsii. Screening of other pathogenic spirochetes with anti-rGpd serum revealed the presence of antigenically related proteins in Borrelia burgdorferi, Treponema pallidum, and Leptospira kirschneri. Further sequence analysis both upstream and downstream of the Gpd homolog showed additional homologs of glycerol metabolism, including a glycerol-3-phosphate transporter (GlpT), a glycerol-3-phosphate dehydrogenase (GlpD), and a thioredoxin reductase (TrxB). AD - Department of Microbiology and Immunology, UCLA School of Medicine, Los Angeles, California 90095, USA. eshang@microimmun.medsch.ucla.edu PMID- 9079909 SO - J Bacteriol 1997 Apr;179(7):2238-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 97228636 AU - Cowan LA AU - Hertzke DM AU - Fenwick BW AU - Andreasen CB TI - Clinical and clinicopathologic abnormalities in greyhounds with cutaneous and renal glomerular vasculopathy: 18 cases (1992-1994). LA - Eng MH - Alanine Aminotransferase/blood MH - Anemia/veterinary MH - Animal MH - Breeding MH - Creatine Kinase/blood MH - *Dog Diseases/blood/genetics/physiopathology MH - Dogs MH - Edema/veterinary MH - Extremities MH - Female MH - Glomerular Filtration Rate/veterinary MH - Male MH - Retrospective Studies MH - Serum Albumin/analysis MH - Skin Ulcer/blood/genetics/*veterinary MH - Support, Non-U.S. Gov't MH - Syndrome MH - Thrombocytopenia/veterinary MH - Uremia/blood/physiopathology/*veterinary RN - EC 2.6.1.2 (Alanine Aminotransferase) RN - EC 2.7.3.2 (Creatine Kinase) RN - 0 (Serum Albumin) PT - JOURNAL ARTICLE DA - 970414 DP - 1997 Mar 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 789-93 SB - M CY - UNITED STATES IP - 6 VI - 210 JC - HAV AA - Author EM - 9706 AB - OBJECTIVE: To determine clinical signs and clinicopathologic abnormalities in Greyhounds with cutaneous and renal glomerular vasculopathy and to determine whether there were any differences between dogs with and without renal azotemia. DESIGN: Retrospective study. ANIMALS: 18 Greyhounds. PROCEDURE: Results of CBC, serum biochemical analyses, urinalyses, coagulation tests, tests of RBC morphology, bacterial culture of blood samples, and serologic tests for Rickettsia rickettsii, Ehrlichia canis, E platys, and Leptospira interrogans were reviewed. Glomerular filtration rates and urine protein:creatinine ratios were determined in most dogs. t-Tests and a test of equality of proportions were used to compare dogs that developed renal azotemia with dogs that did not. RESULTS: None of the dogs was bacteremic or had serologic evidence of infectious disease. Ten dogs had renal azotemia, 16 had anemia, 11 had hypoalbuminemia, and 18 developed thrombocytopenia. Compared with dogs without renal azotemia, dogs with renal azotemia had significantly lower mean platelet count, hematocrit, and serum albumin concentration and significantly higher mean neutrophil count and creatine kinase activity. All 10 dogs with renal azotemia died or were euthanatized; 7 of 8 dogs without azotemia survived. CLINICAL IMPLICATIONS: Greyhounds with cutaneous and renal glomerular vasculopathy that developed renal azotemia had evidence of more severe systemic disease than did dogs that did not have azotemia and, despite supportive treatment, had a poorer prognosis. AD - Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan 66506, USA. PMID- 9074681 SO - J Am Vet Med Assoc 1997 Mar 15;210(6):789-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97398904 AU - Matiash VI TI - [The use of plasmosorption on SKN IK sorbent in a severe course of leptospirosis] LA - Rus MH - Acute Disease MH - Case Report MH - Combined Modality Therapy MH - English Abstract MH - Human MH - Kidney Failure, Acute/etiology/therapy MH - Liver Failure, Acute/etiology/therapy MH - Male MH - Middle Age MH - Sorption Detoxification/instrumentation/*methods MH - Weil's Disease/complications/*therapy PT - JOURNAL ARTICLE DA - 971016 DP - 1997 Mar-Apr IS - 1019-5297 TA - Lik Sprava PG - 105-7 CY - UKRAINE IP - 2 JC - CIU AA - Author EM - 9712 AB - In severe course of icterohemorrhagic form leptospirosis presenting with an acute renal-hepatic insufficiency and manifest hypocoagulation (BC II-III), plasmasorption on the sorbent SKN [correction of CKH] IK with carboperfusion of 0.8-1.2 1 plasma appears to be warranted. Being endowed with an apparent detoxicating effect at the expense of absorbtion of creatinin, urea bilirubin, this manipulation, with small doses of heparin, promotes also stabilization of hemostasis and arresting of hypocoagulation, which fact enhances appreciably the compensatory power of the organism improving the prognosis of the condition. PMID- 9333458 TT - Primenenie plazmosorbtsii na sorbente SKN IK pri tiazhelom techenii leptospiroza. EA - A SO - Lik Sprava 1997 Mar-Apr;(2):105-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97311939 AU - Egorov IE AU - Mironchuk IuV AU - Maramovich AS AU - Chesnokova MV AU - Botvinkin AD AU - Makeev SM AU - Ochirov IuD AU - Vershinin EA AU - Tugutov LD AU - Cherniavskii VF AU - Androsov IA TI - [Zoonotic infections in the central and southern ulusy of the Republic of Sakha] LA - Rus MH - Animal MH - Antibodies, Bacterial/blood MH - Antibodies, Protozoan/blood MH - Bacterial Infections/*epidemiology/immunology/transmission/veterinary MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Reservoirs/statistics & numerical data/veterinary MH - English Abstract MH - Human MH - Rodent Diseases/epidemiology/immunology/transmission MH - Rodentia MH - Seroepidemiologic Methods MH - Siberia/epidemiology MH - Swine MH - Swine Diseases/epidemiology MH - Toxoplasmosis/*epidemiology/immunology/transmission MH - Toxoplasmosis, Animal/epidemiology/transmission MH - Zoonoses/*epidemiology/transmission RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Protozoan) PT - JOURNAL ARTICLE DA - 970804 DP - 1997 Mar-Apr IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 38-43 SB - M CY - RUSSIA IP - 2 JC - Y9O AA - Author EM - 9710 AB - The serological survey of humans, as well as agricultural animals and rodents, for the presence of zoonotic infections, was carried out. Local inhabitants were shown to have contacts with the causative agents of pseudotuberculosis, enteric yersiniosis, tularemia, leptospirosis, Q fever, tick-borne rickettsiosis, chlamydiosis, toxoplasmosis. The immune stratum with respect to enteric yersiniosis was found to have a greater index, while the immune strata with respect to chlamydiosis, Q fever, pseudotuberculosis had the least indices. However, the indices of immune strata perceptibly varied in individual regions. The highest occurrence of antibodies to all above-mentioned zoonotic infections was registered in Megino-Kangalasskii, Amga and Neriungrinskii ulusy [correction of regions]. The probable sources of leptospirosis, toxoplasmosis and Q fever were agricultural animals, while the probable sources of enteric yersiniosis and leptospirosis were rodents. PMID- 9245139 TT - Zoonoznye infektsii v tsentral'nykh i iuzhnykh ulusakh Respubliki Sakha. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1997 Mar-Apr;(2):38-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97320841 AU - Bernasovskaia EP AU - Kondratenko VN AU - Mel'nitskaia EV AU - Lukach IG TI - [The distribution of leptospirae in the icterohaemorrhagiae serogroup] LA - Rus MH - Animal MH - Disease Reservoirs/veterinary MH - English Abstract MH - Guinea Pigs MH - Leptospira interrogans/*isolation & purification/pathogenicity MH - Mice/microbiology MH - Microtinae/microbiology MH - Rats/microbiology MH - Ukraine MH - Virulence PT - JOURNAL ARTICLE DA - 970717 DP - 1997 Mar-Apr IS - 0201-8462 TA - Mikrobiol Z PG - 90-5 CY - UKRAINE IP - 2 VI - 59 JC - BX2 AA - Author EM - 9709 AB - The capacity of leptospiras to get acclimated in the organism of unusual hosts has been studied. Cultures of Icterohaemorrhagiae from musquashes, house mice and field voles have been isolated of leptospirosis sources under intensive epizootics among rats. A possibility to reproduce Leptospira carrying by the cultures of leptospirae of serogroup icterohaemorrhagiae in musquashes and water voles has been shown. One can conclude that under icterohemorrhagic leptospirosis musquashes and water voles can take the part of additional source of infection but they cannot independently preserve leptospirae in nature as a biological species grey rats being their main hosts. PMID- 9221063 TT - Raspredelenie leptospir serogruppy icterohaemorrhagiae. EA - A SO - Mikrobiol Z 1997 Mar-Apr;59(2):90-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 97278566 AU - Hulinska D TI - [Diagnosis of Lyme borreliosis with western blotting] LA - Cze MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial/immunology MH - *Blotting, Western MH - Borrelia/genetics/*immunology MH - Borrelia burgdorferi/genetics/immunology MH - Cross Reactions MH - DNA, Viral/analysis MH - English Abstract MH - Human MH - Lyme Disease/*diagnosis MH - Polymerase Chain Reaction MH - Sensitivity and Specificity MH - Serodiagnosis MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (DNA, Viral) PT - JOURNAL ARTICLE DA - 970523 DP - 1997 Mar IS - 0009-5222 TA - Epidemiol Mikrobiol Imunol PG - 3-8 CY - CZECH REPUBLIC IP - 1 VI - 46 JC - B10 AA - Author EM - 9707 AB - Spirochetes Borrelia burgdorferi sensu lato, selected as antigens for Western blot analyses were isolated from cerebrospinal (strain 192 M) and from blood (strain Kc90) and identified by means of monoclonal antibodies and the polymerase chain reaction (PCR) as B. garinii and B. afzelii. Differences between B. garinii and B. afzelii are in the genotype of the surface protein OspA and OspB, internal flagellin (Fla II) and the main extracellular protein (MEP). The reaction of polyclonal antibodies in 918 serum specimens and 180 specimens of cerebrospinal fluid was investigated in IgG and IgM immunoblots in patients with neurological symptoms, arthritis and skin manifestations suspect of Lyme borreliosis. Confirmation of the immunoenzyme ELISA reaction by means of immunoblots in the acute stage of borreliosis, in clinically obscure cases, in herpetic infection, mononucleosis and leptospirosis revealed a higher sensitivity and specificity of Western blot. Proteins of B. garinii with a molecular weight of 94, 84, 66, 60, 56, 41, 39, 33, 29, 22, 18 and 14 kDa were detected in the reaction with monoclonal antibodies and immunoglobulins of patients suffering from barreliosis. The frequency and intensity of the reaction of these antigens differed markedly in sera of patients suffering from borreliosis and sera of patients who suffered from a different infection. The external surface antigen OspA, OspB, OspC and protein with 39 kDA are significant markers of borreliosis. The most frequently detected antigens in cross reactions with immunoglobulins against other pathogens are proteins P66, P60, P41 which are dominant immunogens of all types of borrelias and moreover a humoral response to them develops in the acute stage of the disease. In arthritis and neuroborreliosis a different in IgG immunoblots was found. AD - Narodni referencni laborator pro lymeskou boreliozu, Statni zdravotni ustav, Praha. PMID- 9162453 TT - Poznatky o lymeske borelioze vysetrene pomoci western blotu. EA - A SO - Epidemiol Mikrobiol Imunol 1997 Mar;46(1):3-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [98 medline neighbors] UI - 97275763 AU - Marotto PC AU - Marotto MS AU - Santos DL AU - Souza TN AU - Seguro AC TI - Outcome of leptospirosis in children. LA - Eng MH - Adolescence MH - Ampicillin/*therapeutic use MH - Aspartate Aminotransferase/blood MH - Bilirubin/blood MH - Brazil/epidemiology MH - Child MH - Child, Preschool MH - Creatinine/blood MH - Developing Countries MH - Female MH - Fever MH - Hemorrhage MH - Human MH - Immune Sera/immunology MH - Jaundice MH - Kidney Failure, Acute MH - Leptospira interrogans/immunology MH - Male MH - Meningitis, Bacterial MH - Penicillin G/*therapeutic use MH - Penicillins/*therapeutic use MH - Prognosis MH - Retrospective Studies MH - Thrombocytopenia MH - Treatment Outcome MH - Weil's Disease/*drug therapy/epidemiology RN - EC 2.6.1.1 (Aspartate Aminotransferase) RN - 0 (Immune Sera) RN - 0 (Penicillins) RN - 60-27-5 (Creatinine) RN - 61-33-6 (Penicillin G) RN - 635-65-4 (Bilirubin) RN - 69-53-4 (Ampicillin) PT - JOURNAL ARTICLE DA - 970508 DP - 1997 Mar IS - 0002-9637 TA - Am J Trop Med Hyg PG - 307-10 SB - A SB - M CY - UNITED STATES IP - 3 VI - 56 JC - 3ZQ AA - Author EM - 9707 AB - We conducted a retrospective analysis of 43 consecutive children (35 boys and 8 girls), 4-14 years of age and living in an urban area, who were hospitalized at the Instituto de Infectologia Emilio Ribas (Sao Paulo, Brazil) from January 1989 to December 1995 with an acute illness subsequently diagnosed as leptospirosis. Epidemiologic data indicated contact with contaminated water in most cases (88%). The patient sera reacted most strongly with Leptospira interrogans serovars copenhageni (45%) and icterohaemorrhagiae (32.7%). Jaundice was present in 70% of the patients, elevated transaminase levels in 56%, renal failure in 79%, meningitis in 23%, thrombocytopenia in 65%, and hemorrhagic manifestations in 11.6%. Three children had pulmonary hemorrhage with respiratory failure and one death occurred as a consequence of respiratory failure. We also observed that antimicrobial therapy reduced the extent of renal failure and thrombocytopenia. These data indicate that antibiotics benefit children with late, severe leptospirosis and that severe disease also occurs in children and should be considered in the differential diagnosis. AD - Instituto de Infectologia Emilio Ribas, Sao Paulo, Brazil. PMID- 9129533 SO - Am J Trop Med Hyg 1997 Mar;56(3):307-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97256279 AU - Lombardi R TI - Acute renal failure in leptospirosis in Uruguay. LA - Eng MH - Adult MH - Age Distribution MH - *Developing Countries MH - Female MH - Human MH - Incidence MH - Kidney Failure, Acute/*epidemiology/*etiology/physiopathology MH - Leptospirosis/*complications/epidemiology MH - Male MH - Middle Age MH - Risk Factors MH - Sex Distribution MH - Survival Rate MH - Uruguay/epidemiology PT - JOURNAL ARTICLE DA - 970717 DP - 1997 Mar IS - 0886-022X TA - Ren Fail PG - 315-8 SB - M CY - UNITED STATES IP - 2 VI - 19 JC - RCG AA - Author EM - 9709 AB - The present study was carried out to describe epidemiology and clinical pattern of acute renal failure caused by leptospirosis in Uruguay. For these purposes, all literature published in Uruguay was reviewed. Three studies were analyzed: 2 series of patients and 1 case report that summarize 26 cases. The incidence of acute renal failure found in the first study was 8% and in the second one, 15%. The first study included only dialyzed patients, which could explain the aforementioned difference. The estimated annual incidence of leptospirosis in Uruguay is about 10 cases/year. Therefore, the expected incidence of acute renal failure due to leptospirosis is of 0.7-1.3 cases/year. All but 1 case were males. Mean age was 35 +/- 14.5. Source of infection was known in 23/26. Typical symptoms were: fever 26/26, myalgias 22/26, dehydration 21/26, jaundice 21/26, conjunctival suffusion 20/26, and digestive disturbance 18/26. Bleeding and meningitis were infrequent (8/26, 5/26, respectively). Acute renal failure was intrinsic in 18/26. Nonoliguric forms were predominant (14/18). Kalemia was low or normal in 22/26 cases. Dialysis was performed in 9/26 cases, but the number of dialyses per patient was high (9.4 +/- 4). The survival rate was 23/26. We concluded that leptospirosis is an infrequent cause of acute renal failure in Uruguay, with an expected frequency of approximately 1 case/year. Clinical picture was typical and contact was frequently known, which made diagnosis easy. Acute renal failure was predominantly polyuric and with low or normal kalemia; survival rate was high. AD - Centro de Nefrologia, Hospital de Clinicas, Universidad de la Republica, Montevideo, Uruguay. PMID- 9101610 SO - Ren Fail 1997 Mar;19(2):315-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 97256259 AU - Abdulkader RC TI - Acute renal failure in leptospirosis. LA - Eng MH - Adult MH - Aged MH - Brazil/epidemiology MH - Developing Countries MH - Human MH - Incidence MH - Kidney/pathology/parasitology MH - Kidney Failure, Acute/*epidemiology/*etiology/pathology/prevention & control/physiopathology MH - Leptospirosis/*complications/epidemiology MH - Male MH - Middle Age MH - Prognosis MH - Survival Rate PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 970717 DP - 1997 Mar IS - 0886-022X TA - Ren Fail PG - 191-8 SB - M CY - UNITED STATES IP - 2 VI - 19 JC - RCG EM - 9709 AD - Faculdade de Medicina da Universidade de Sao Paulo, Laboratorio de Fisiopatologia Renal, Brazil. RF - 34 PMID- 9101590 SO - Ren Fail 1997 Mar;19(2):191-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97251703 AU - Hill MK AU - Sanders CV TI - Leptospiral pneumonia. LA - Eng MH - Animal MH - Animals, Domestic MH - Antibiotics/therapeutic use MH - Cats MH - Diagnosis, Differential MH - Dogs MH - Human MH - *Leptospirosis/diagnosis/drug therapy/immunology/transmission MH - *Pneumonia, Bacterial/diagnosis/drug therapy/immunology/transmission MH - Rats MH - *Zoonoses/transmission RN - 0 (Antibiotics) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 970624 DP - 1997 Mar IS - 0882-0546 TA - Semin Respir Infect PG - 44-9 SB - M CY - UNITED STATES IP - 1 VI - 12 JC - SEI AA - Author EM - 9708 AB - Leptospirosis, a spirochetal infection, causes a wide spectrum of disease ranging from asymptomatic infection, or influenza-like symptoms, to severe jaundice and renal failure. Humans become infected through skin or mucous membrane contact with infected animal urine or urine-contaminated water or soil. The most common source of human infection worldwide is rats. However, in the United States, dogs, livestock, wild mammals, and cats are also sources. Once leptospires penetrate mucous membranes or breaks in the skin, they disseminate to all parts of the body. Five to ten percent of those infected will have severe leptospirosis with jaundice, known as Weil's disease. The classical presentation of leptospirosis is that of a biphasic illness. The initial septicemic phase lasts 4 to 7 days and is characterized most commonly as a mild influenza-like illness. During the secondary immune phase, leptospires disappear from the blood and cerebrospinal fluid. However, circulating antibodies cause immune-mediated meningitis, uveitis, rash, and, very rarely, circulatory collapse associated with Weil's disease. Pulmonary involvement occurs in 20% to 70% of patients. The more severe pulmonary manifestations are rare. Although attempts should be made to isolate leptospires from the blood or cerebrospinal fluid, the diagnosis is usually established by serologic tests. The effectiveness of antimicrobial therapy in treating leptospirosis has been difficult to assess because of the high variability of the disease's clinical course, although in severe cases, antibiotic therapy is effective even when treatment is delayed. Prevention is difficult because it is almost impossible to eliminate the large animal reservoir of infection. AD - Louisiana State University School of Medicine at New Orleans 70112, USA. RF - 42 PMID- 9097376 SO - Semin Respir Infect 1997 Mar;12(1):44-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [97 medline neighbors] UI - 97218682 AU - Murgia R AU - Riquelme N AU - Baranton G AU - Cinco M TI - Oligonucleotides specific for pathogenic and saprophytic leptospira occurring in water. LA - Eng MH - DNA, Bacterial/analysis MH - Leptospira/*genetics/*isolation & purification MH - Molecular Sequence Data MH - Oligonucleotides MH - Polymerase Chain Reaction MH - Sensitivity and Specificity MH - Sequence Homology, Amino Acid MH - Support, Non-U.S. Gov't MH - *Water Microbiology RN - 0 (DNA, Bacterial) RN - 0 (Oligonucleotides) PT - JOURNAL ARTICLE DA - 971119 DP - 1997 Mar 1 IS - 0378-1097 TA - FEMS Microbiol Lett PG - 27-34 SB - M CY - NETHERLANDS IP - 1 VI - 148 JC - FML AA - Author EM - 9801 AB - Sets of primers specific for both pathogenic (SPL) and saprophytic (SSL) Leptospira were designed from ribosomal 16S genes (rrs) available in databases. They were used as two sets of primer pairs for the PCR amplification of known pathogenic and saprophytic strains. It was possible to identify pathogenic strains by the use of SPL primers and saprophytic ones by SSL primers. Serovars from L. meyeri, of controversial pathogenicity status, confirmed the heterogeneity of the species representatives in this respect. Serovars ranarum, sofia and perameles were amplified by SPL and not SSL. Conversely, serovar semaranga was amplified by SSL and not SPL. In order to use SPL primers for the detection of pathogenic leptospires from a natural water environment, we set up an additional semi-nested PCR by employing a second internal primer which succeeded in detecting as few as 5 pathogenic leptospires per ml of water. AD - Dipartimento di Scienze Biomediche, Universita di Trieste, Italy. PMID- 9066106 SO - FEMS Microbiol Lett 1997 Mar 1;148(1):27-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97382119 AU - Younes-Ibrahim M AU - Buffin-Meyer B AU - Cheval L AU - Burth P AU - Castro-Faria MV AU - Barlet-Bas C AU - Marsy S AU - Doucet A TI - Na,K-ATPase: a molecular target for Leptospira interrogans endotoxin. LA - Eng MH - Animal MH - Endotoxins/*physiology MH - H(+)-K(+)-Exchanging ATPase/*physiology MH - *Leptospira interrogans MH - Na(+)-K(+)-Exchanging ATPase/*physiology MH - Rabbits MH - Support, Non-U.S. Gov't RN - EC 3.6.1.36 (H(+)-K(+)-Exchanging ATPase) RN - EC 3.6.1.37 (Na(+)-K(+)-Exchanging ATPase) RN - 0 (Endotoxins) PT - JOURNAL ARTICLE DA - 971113 DP - 1997 Feb IS - 0100-879X TA - Braz J Med Biol Res PG - 213-23 SB - M CY - BRAZIL IP - 2 VI - 30 JC - BOF AA - Author EM - 9801 AB - On the basis of our report that a glycolipoprotein fraction (GLP) extracted from Leptospira interrogans contains a potent inhibitor of renal Na,K-ATPase, we proposed that GLP-induced inhibition of Na,K- ATPase might be the primary cellular defect in the physiopathology of leptospirosis. The present study was designed to test this hypothesis by determining whether or not 1). GLP inhibits all the isoforms of Na,K- ATPase which are expressed in the tissues affected by leptospirosis, 2) Na,K-ATPase from leptospirosis-resistant species, such as the rat, is sensitive to GLP, 3) GLP inhibits Na,K-ATPase from intact cells, and 4) GLP inhibits ouabain-sensitive H,K-ATPase. The results indicate that in the rabbit, a leptospirosis-sensitive species, GLP inhibits with similar efficiency (apparent IC50: 120-220 micrograms protein GLP/ml) all isoforms of Na,K-ATPase known to be expressed in target tissues for the disease. Na,K-ATPase from rat kidney displays a sensitivity to GLP similar to that of the rabbit kidney enzyme (apparent IC50: 25-80 and 50-150 micrograms protein GLP/ml for rat and rabbit, respectively), indicating that resistance to the disease does not result from the resistance of Na,K-ATPase to GLP. GLP also reduces ouabain-sensitive rubidium uptake in rat thick ascending limbs (pmol mm-1 min-1 +/- SEM; control: 23.8 +/- 1.8; GLP, 88 micrograms protein/ml: 8.2 +/- 0.9), demonstrating that it is active in intact cells. Finally, GLP had no demonstrable effect on renal H,K-ATPase activity, even on the ouabain- sensitive form, indicating that the active principle of GLP is more specific for Na,K-ATPase than ouabain itself. Although the hypothesis remains to be demonstrated in vivo, the present findings are compatible with the putative role of GLP-induced inhibition of Na,K-ATPase as an initial mechanism in the physiopathology of leptospirosis. AD - Laboratoire de Biologie Integree des Cellules Renales, CNRS URA 1859, Commissariat a l'Energie Atomique, Saclay, France. PMID- 9239307 SO - Braz J Med Biol Res 1997 Feb;30(2):213-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97239337 AU - Perrocheau A AU - Perolat P TI - Epidemiology of leptospirosis in New Caledonia (South Pacific): a one- year survey. LA - Eng MH - Adolescence MH - Adult MH - Age Distribution MH - Aged MH - Aged, 80 and over MH - Animal MH - Chi-Square Distribution MH - Child MH - Child, Preschool MH - Environmental Exposure/statistics & numerical data MH - Female MH - Human MH - Incidence MH - Leptospira/classification/isolation & purification MH - Leptospirosis/*epidemiology/microbiology/physiopathology/transmission MH - Male MH - Middle Age MH - New Caledonia/epidemiology MH - Rain MH - Residence Characteristics MH - Retrospective Studies MH - Seasons MH - Seroepidemiologic Methods PT - JOURNAL ARTICLE DA - 970701 DP - 1997 Feb IS - 0392-2990 TA - Eur J Epidemiol PG - 161-7 SB - M CY - NETHERLANDS IP - 2 VI - 13 JC - ERE AA - Author EM - 9709 AB - We describe a series of 144 cases of leptospirosis diagnosed in 1989 in New Caledonia. The incidence rate was 90 per 100,000 person-years, with a specific mortality rate of 4% patients. Those affected (100 males, 44 females) were mainly aged 20 to 40 years. Incidence in rural areas (112 per 100,000 person-years) was seven times higher than in urban settlements. Two periods with higher incidence were noticed corresponding to highest rainfall. Twenty-nine of the cases occurred in individuals with professions commonly associated with leptospirosis. Contacts with rats, dogs and ditch or river water were the most frequently mentioned. The clinical expression of the disease was polymorphic: 60% of the patients had mild symptoms, 40% were acute forms including Weil's disease. Of 57 hospitalized, 23% were admitted with an initial diagnosis of dengue, and 37% with leptospirosis. Main clinical syndromes were: icterus and/or renal syndrome in 50% of patients, cardiac syndrome in 65%, acute myalgies in 58% and pulmonary syndrome in 50%. Although hemorrhages were uncommon (17%), 40% of the cases demonstrated thrombocytopenia (< 50,000/m3). Pancreatic involvement with hyperamylasemia was evidenced in 50% of cases. Twelve serogroups of Leptospira were implicated, Icterohaemorragiae predominated (41%), but was not associated with severe forms. In New Caledonia, like in all tropics, leptospirosis must be considered as an environmental diseases, professional activities being just an additional risk factor. Use of serology as a reliable tool for confirmation of cases in areas of high environmental contamination is discussed. AD - Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA. PMID- 9084999 SO - Eur J Epidemiol 1997 Feb;13(2):161-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97235959 AU - Nicodemo AC AU - Duarte MI AU - Alves VA AU - Takakura CF AU - Santos RT AU - Nicodemo EL TI - Lung lesions in human leptospirosis: microscopic, immunohistochemical, and ultrastructural features related to thrombocytopenia. LA - Eng MH - Adult MH - Antigens, Bacterial/analysis MH - Blood Platelets/immunology/metabolism/ultrastructure MH - Capillaries/parasitology/ultrastructure MH - Cell Adhesion MH - Endothelium, Vascular/metabolism/parasitology/ultrastructure MH - Female MH - Fibrin/analysis/immunology MH - Hemorrhage/etiology MH - Human MH - Immunohistochemistry MH - Leptospira interrogans/immunology/isolation & purification MH - Lung/blood supply/*pathology/ultrastructure MH - Lung Diseases/etiology MH - Male MH - Microscopy, Electron MH - Middle Age MH - Platelet Aggregation MH - Thrombocytopenia/*etiology/pathology MH - Weil's Disease/complications/*pathology RN - 0 (Antigens, Bacterial) RN - 9001-31-4 (Fibrin) PT - JOURNAL ARTICLE DA - 970410 DP - 1997 Feb IS - 0002-9637 TA - Am J Trop Med Hyg PG - 181-7 SB - A SB - M CY - UNITED STATES IP - 2 VI - 56 JC - 3ZQ AA - Author EM - 9706 AB - Lung fragments from 12 patients were collected immediately after death and studied by light and electron microscopy and by immunohistochemistry to describe the main morphologic and ultrastructural aspects of the lung and platelets in leptospirosis (Weil's syndrome), to search for the possibility of disseminated intravascular coagulation (DIC), and to assess the relationship between endothelial lesions and local platelet aggregation and the leptospiral antigen distribution, as well as its relationship with the intensity of the lesions. The immunohistochemical results for fibrin aggregates were positive in the lumen and/or on the vascular endothelium in nine cases and on the alveolar surface in seven cases, leading to the diagnosis of the adult respiratory distress syndrome in these seven cases. Test results for leptospiral antigen by immunohistochemistry were positive in eight cases with no direct relationship between antigen deposits in the pulmonary vascular endothelium and intensity of the lesions. The ultrastructural findings were uniform and constant. Capillary lesions were characterized by swelling of endothelial cells, an increase in pinocytotic vesicles, and giant dense bodies in the cytoplasm of these cells. No necrosis, rupture, nor exposed subendothelial collagen was observed outside the hemorrhagic areas, and the intercellular junctions were preserved. The lung involvement in severe human leptospirosis presents as hemorrhagic pneumopathy with septal capillary lesions that are the usual cause of death. The thrombocytopenia that was verified in 11 of 12 patients in our study seems to bear no relationship to DIC and seems to be determined by activation, adhesion, and aggregation of platelets to the stimulated vascular endothelium, with an amorphous electron-dense substance between the endothelial cells and the adherent platelets in places where the subendothelial collagen was not exposed. AD - Department of Infectious Diseases, University of Sao Paulo Medical School, Brazil. PMID- 9080878 SO - Am J Trop Med Hyg 1997 Feb;56(2):181-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97219690 AU - Durham PJ AU - Paine GD TI - Serological survey for antibodies to infectious agents in beef cattle in northern South Australia [published erratum appears in Aust Vet J 1997 Apr;75(4):273] LA - Eng MH - Animal MH - Antibodies, Bacterial/*blood MH - Antibodies, Viral/*blood MH - Bovine Virus Diarrhea-Mucosal Disease/epidemiology/immunology MH - Cattle MH - Cattle Diseases/blood/epidemiology/*immunology MH - Chlamydia/immunology MH - Chlamydia Infections/epidemiology/immunology/veterinary MH - Coxiella burnetii/immunology MH - Diarrhea Virus, Bovine Viral/immunology MH - Enzyme-Linked Immunosorbent Assay/methods/veterinary MH - Ephemeral Fever/epidemiology/immunology MH - Ephemeral Fever Virus, Bovine/immunology MH - Leptospira interrogans/immunology MH - Mycobacterium Infections/epidemiology/immunology/veterinary MH - Mycobacterium paratuberculosis/immunology MH - Paramyxovirus/immunology MH - Paramyxovirus Infections/epidemiology/immunology MH - Q Fever/epidemiology/immunology/veterinary MH - South Australia/epidemiology MH - Support, Non-U.S. Gov't MH - Weil's Disease/epidemiology/immunology/veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 970520 DP - 1997 Feb IS - 0005-0423 TA - Aust Vet J PG - 139-40 SB - M CY - AUSTRALIA IP - 2 VI - 75 JC - 9IE EM - 9707 AD - Central Veterinary Laboratory, Department of Primary Industries, Adelaide, South Australia. RO - M:MWS PMID- 9066974 LR - 970910 SO - Aust Vet J 1997 Feb;75(2):139-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 97214499 AU - Brown PD AU - Levett PN TI - Differentiation of Leptospira species and serovars by PCR-restriction endonuclease analysis, arbitrarily primed PCR and low-stringency PCR. LA - Eng MH - Animal MH - Dogs MH - DNA Fingerprinting MH - DNA, Bacterial/*analysis/isolation & purification MH - Human MH - Leptospira/*classification/genetics/isolation & purification MH - *Polymerase Chain Reaction MH - Polymorphism, Restriction Fragment Length MH - Rats MH - Reproducibility of Results MH - *Restriction Mapping MH - Templates RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 970324 DP - 1997 Feb IS - 0022-2615 TA - J Med Microbiol PG - 173-81 SB - M CY - ENGLAND IP - 2 VI - 46 JC - J2N AA - Author EM - 9705 AB - Reference strains from 30 serovars representing seven species of Leptospira and 48 recent isolates from human patients, dogs and rats, were characterised by polymerase chain reaction-restriction endonuclease analysis (PCR-REA), arbitrarily primed PCR (AP-PCR) and low stringency PCR (LS-PCR). PCR-REA analysis yielded seven groups among 29 serovars of pathogenic Leptospira; the non-pathogenic L. biflexa serovar patoc was not amplified with the primer pairs studied. AP-PCR and LS-PCR fingerprinting resulted in 25 and 21 distinct profiles, respectively, among the 30 reference strains. The results of the three PCR-based techniques were highly concordant and were in general agreement with those from previous DNA studies, confirming the high level of polymorphism among Leptospira species and serovars, and supported the concept of the serovar as the basic taxonomic unit of leptospiral classification. Results of the PCR-based typing methods for 11 randomised leptospiral strains, 36 clinical isolates from human patients and dogs and 12 survey isolates from trapped rats agreed with those from serological identification. With one exception, isolates of the same serovar gave identical profiles irrespective of the source. AP- PCR and LS-PCR are simple to perform and interpret, and appear to be useful for characterising isolates of Leptospira spp. for diagnostic and epidemiological purposes. AD - School of Clinical Medicine and Research, University of the West Indies, Barbados, West Indies. PMID- 9060879 SO - J Med Microbiol 1997 Feb;46(2):173-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 97189938 AU - Katz AR AU - Sasaki DM AU - Mumm AH AU - Escamilla J AU - Middleton CR AU - Romero SE TI - Leptospirosis on Oahu: an outbreak among military personnel associated with recreational exposure. LA - Eng MH - *Disease Outbreaks/statistics & numerical data MH - Hawaii/epidemiology MH - Human MH - Incidence MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - *Military Personnel MH - Risk Factors MH - Swimming PT - JOURNAL ARTICLE DA - 970328 DP - 1997 Feb IS - 0026-4075 TA - Mil Med PG - 101-4 CY - UNITED STATES IP - 2 VI - 162 JC - N1A AA - Author EM - 9706 AB - In December 1992, a common-source waterborne outbreak of leptospirosis occurred on the island of Oahu in the state of Hawaii. Two male service persons were hospitalized with culture-confirmed leptospirosis. Eighteen others had similar histories of exposure to the same freshwater swimming site. Although six men developed signs and symptoms comparable to those of the two confirmed cases, none manifested culture or serologic evidence of leptospirosis. The increased incidence of leptospirosis in Hawaii coupled with an increased risk in young males characterize the military population in Hawaii as a high-risk population with respect to leptospirosis. AD - Department of Public Health Sciences, School of Public Health, University of Hawall, Honolulu 96822, USA. PMID- 9038027 SO - Mil Med 1997 Feb;162(2):101-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97180301 AU - Dobrosielski-Vergona K TI - Alterations in specific activity of glucose-6-phosphatase in laboratory rats after leptospiral exposure followed by triiodothyronine administration. LA - Eng MH - Animal MH - Enzyme Induction MH - Glucose-6-Phosphatase/*biosynthesis MH - Leptospirosis/*enzymology MH - Male MH - Microsomes, Liver/drug effects/*enzymology MH - Rats MH - Rats, Inbred F344 MH - Reference Values MH - Support, U.S. Gov't, P.H.S. MH - Triiodothyronine/*pharmacology RN - EC 3.1.3.9 (Glucose-6-Phosphatase) RN - 6893-02-3 (Triiodothyronine) PT - JOURNAL ARTICLE ID - AG-00439/AG/NIA ID - AG-005060/AG/NIA DA - 970603 DP - 1997 Feb IS - 0002-9645 TA - Am J Vet Res PG - 143-5 SB - M CY - UNITED STATES IP - 2 VI - 58 JC - 40C AA - Author EM - 9708 AB - OBJECTIVE: To determine the effect of leptospirosis on thyroid hormone induction of the specific activity of hepatic microsomal glucose-6- phosphatase in laboratory rats. ANIMALS: Male Fisher 344 rats, 6 and 24 months old, healthy and infected with leptospirosis. PROCEDURE: The maximal velocity of glucose-6-phosphatase in intact and detergent- disrupted hepatic microsomes was assayed in duplicate or triplicate at 5 substrate concentrations, by monitoring the release of inorganic phosphate at 0-, 5-, and 10-minute intervals. The method of least squares was used to determine the velocity of the reactions. The level of statistical significance was determined, using the Student's t-test for unpaired data. Thyroid hormone (40 micrograms of T3/ 100 g of body weight) was administered for 5 consecutive days prior to sacrifice. RESULTS: Leptospirosis significantly increased the specific activity of the translocase component of glucose-6-phosphatase in old, but not young, rats. The activity of the translocase increased more than three- fold in untreated, infected old animals, compared with untreated, healthy old animals. Thyroid hormone induced a two- and threefold increase in the specific activities of the translocase in young and old healthy animals, respectively. Thyroid hormone did not increase the activity of the translocase in old animals infected with leptospirosis. CONCLUSIONS AND CLINICAL RELEVANCE: Leptospirosis alters the specific activity and induction by thyroid hormone of the translocase component of hepatic microsomal glucose-6-phosphatase in old male Fisher 344 rats. It is necessary to be aware of possible alterations in hepatic membrane-bound enzymes after leptospiral infection of older laboratory animals. AD - Department of Anatomy/Histology, School of Dental Medicine, University of Pittsburgh, PA 15261, USA. PMID- 9028477 SO - Am J Vet Res 1997 Feb;58(2):143-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [6 protein links] [1 nucleotide link] [104 medline neighbors] UI - 97175555 AU - Mitchison M AU - Bulach DM AU - Vinh T AU - Rajakumar K AU - Faine S AU - Adler B TI - Identification and characterization of the dTDP-rhamnose biosynthesis and transfer genes of the lipopolysaccharide-related rfb locus in Leptospira interrogans serovar Copenhageni. LA - Eng MH - ABC Transporters/genetics MH - Bacterial Proteins/genetics MH - Carbohydrate Isomerases/genetics MH - Cloning, Molecular MH - Escherichia coli/genetics MH - *Genes, Bacterial MH - Genetic Complementation Test MH - Hexosyltransferases/genetics MH - Hydro-Lyases/genetics MH - Leptospira interrogans/*genetics/metabolism MH - Lipopolysaccharides/*biosynthesis MH - Mannosephosphate Isomerase/genetics MH - Molecular Sequence Data MH - Nucleoside Diphosphate Sugars/*biosynthesis/metabolism MH - Nucleotidyltransferases/genetics MH - RNA, Bacterial/genetics MH - RNA, Messenger/genetics MH - Shigella flexneri/genetics MH - Support, Non-U.S. Gov't MH - Thymine Nucleotides/*biosynthesis/metabolism RN - EC 2.4.1. (Hexosyltransferases) RN - EC 2.4.1.- (LPS rhamnosyltransferases) RN - EC 2.7.7 (Nucleotidyltransferases) RN - EC 2.7.7.- (dTDP-D-glucose synthase) RN - EC 2.7.7.- (dTDP-L-rhamnose synthase) RN - EC 4.2.1. (Hydro-Lyases) RN - EC 4.2.1.46 (dTDPglucose 4,6-dehydratase) RN - EC 5.- (Carbohydrate Isomerases) RN - EC 5.1.3.- (TDP-deoxyglucose epimerase) RN - EC 5.3.1.8 (Mannosephosphate Isomerase) RN - 0 (ABC Transporters) RN - 0 (Bacterial Proteins) RN - 0 (Lipopolysaccharides) RN - 0 (Nucleoside Diphosphate Sugars) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Messenger) RN - 0 (Thymine Nucleotides) RN - 2147-59-3 (thymidine diphosphate rhamnose) PT - JOURNAL ARTICLE DA - 970307 DP - 1997 Feb IS - 0021-9193 TA - J Bacteriol PG - 1262-7 SB - M CY - UNITED STATES IP - 4 VI - 179 JC - HH3 AA - Author EM - 9705 AB - Immunity to leptospirosis is principally humorally mediated and involves opsonization of leptospires for phagocytosis by macrophages and neutrophils. The only protective antigen identified to date is the leptospiral lipopolysaccharide (LPS), which biochemically resembles typical gram-negative LPS but has greatly reduced endotoxic activity. Little is known about the structure of leptospiral LPS. A 2.1-kb EcoRI fragment from the chromosome of serovar Copenhageni was cloned in pUC18 in Escherichia coli, after which flanking regions were cloned from a genomic library constructed in bacteriophage lambda GEM12. Sequence analysis identified four open reading frames which showed similarity to the rfbC, rfbD, rfbB, and rfbA genes, transcribed in that order, which encode the four enzymes involved in the biosynthesis of dTDP-rhamnose for the assembly of LPS in Salmonella enterica, E. coli, and Shigella flexneri. An additional open reading frame downstream of the rfbCDBA locus showed similarity with the rhamnosyltransferase genes of Shigella and Yersinia enterocolitica but not Salmonella. Comparison of deduced amino acid sequences showed up to 85% similarity of the leptospiral proteins with those of other gram-negative bacteria. Polyacrylamide gel electrophoresis of recombinant clones identified the putative RfbCDBA proteins, while reverse transcriptase-mediated PCR analysis indicated that the rfbCDBA gene cluster was expressed in Leptospira. Moreover, it could restore normal LPS phenotype to a defined rfbB::Tn5 mutant of S. flexneri which was deficient in all four genes, thereby confirming the functional identification of a part of the leptospiral rfb locus. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 9023210 SI - GENBANK/U61226 SO - J Bacteriol 1997 Feb;179(4):1262-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 97162349 AU - Merien F AU - Baranton G AU - Perolat P TI - Invasion of Vero cells and induction of apoptosis in macrophages by pathogenic Leptospira interrogans are correlated with virulence. LA - Eng MH - Animal MH - *Apoptosis MH - Bacterial Adhesion MH - Cercopithecus aethiops MH - Cytochalasin D/pharmacology MH - DNA Fragmentation MH - Eukaryotic Cells/microbiology MH - Formaldehyde/pharmacology MH - Kinetics MH - Leptospira interrogans/drug effects/growth & development/*pathogenicity MH - Macrophages/metabolism/*microbiology MH - Mice MH - Support, Non-U.S. Gov't MH - Vero Cells MH - Virulence RN - 22144-77-0 (Cytochalasin D) RN - 50-00-0 (Formaldehyde) PT - JOURNAL ARTICLE DA - 970221 DP - 1997 Feb IS - 0019-9567 TA - Infect Immun PG - 729-38 SB - M SB - X CY - UNITED STATES IP - 2 VI - 65 JC - GO7 AA - Author EM - 9705 AB - Interactions of virulent Leptospira interrogans serovar icterohaemorrhagiae strain Verdun with Vero cells (African green monkey kidney fibroblasts) and a monocyte-macrophage-like cell line (J774A.1) were assayed by a double-fluorescence immunolabelling method. Infectivity profiles were investigated according to (i) the duration of contact between leptospires and eukaryotic cells and (ii) the number of in vitro passages after primary isolation from lethally infected guinea pigs. Comparative experiments were conducted with the corresponding high-passage avirulent variant and the saprophytic leptospire Leptospira biflexa Patoc I. In Vero cells, virulent leptospires were quickly internalized from 20 min postinfection, whereas avirulent and saprophytic strains remained extracellularly located. In addition, the virulent strain demonstrated an ability to actively invade the monocyte- macrophage-like J774A.1 cells during the early stages of contact and to induce programmed cell death, as shown by the detection of oligonucleosomes in a quantitative sandwich enzyme immunoassay. In both cellular systems, subsequent in vitro subcultures demonstrated a progressive decrease of the invasiveness, pointing out the necessity of using primocultures of Leptospira for virulence studies. Invasiveness of virulent leptospires was significantly inhibited with monodansylcadaverine, indicating that internalization was dependent on receptor-mediated endocytosis. Invasion of epithelial cells and induction of apoptosis in macrophages may be related to the pathogenicity of Leptospira, and both could contribute to its ability to survive in the host and to escape from the immune response. AD - Laboratoire des Leptospires, Institut Pasteur, Noumea, New Caledonia, France. PMID- 9009336 SO - Infect Immun 1997 Feb;65(2):729-38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 97167231 AU - Monsuez JJ AU - Kidouche R AU - Le Gueno B AU - Postic D TI - Leptospirosis presenting as haemorrhagic fever in visitor to Africa [letter] LA - Eng MH - Adult MH - Africa MH - Ampicillin/therapeutic use MH - Case Report MH - Diagnosis, Differential MH - Female MH - France MH - Hemorrhagic Fevers, Viral/*diagnosis MH - Human MH - Leptospirosis/*diagnosis/drug therapy/transmission MH - Penicillins/therapeutic use MH - *Travel RN - 0 (Penicillins) RN - 69-53-4 (Ampicillin) PT - LETTER DA - 970225 DP - 1997 Jan 25 IS - 0140-6736 TA - Lancet PG - 254-5 SB - A SB - M SB - X CY - ENGLAND IP - 9047 VI - 349 JC - L0S EM - 9705 PMID- 9014920 SO - Lancet 1997 Jan 25;349(9047):254-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97234287 AU - Smythe L AU - Dohnt M AU - Norris M AU - Symonds M AU - Scott J TI - Review of leptospirosis notifications in Queensland 1985 to 1996. LA - Eng MH - Abattoirs MH - Disease Notification MH - Human MH - Leptospirosis/*epidemiology/transmission MH - Occupational Diseases/*epidemiology MH - Queensland/epidemiology MH - Risk Factors PT - JOURNAL ARTICLE DA - 970509 DP - 1997 Jan 23 IS - 0725-3141 TA - Commun Dis Intell PG - 17-20 CY - AUSTRALIA IP - 2 VI - 21 JC - CUB AA - Author EM - 9707 AB - To provide an overview of leptospirosis in Queensland, the World Health Organization/Food and Agriculture Organization Collaborating Centre for Reference and Research on Leptospirosis undertook a study of notifications of the disease from 1985 to 1996. The review encompassed information drawn from notifications to Queensland Health and questionnaires sent to doctors. Notifications were highest between February and July and the highest population rates were identified in the Central West and Peninsula Health Regions. Ninety-one per cent of notifications were for males. At risk population groups included meat workers, those working with farm animals and banana workers. The study found the incidence of leptospirosis was higher in 1996 than in previous years. Improved diagnosis and surveillance will aid our understanding of the preventable risk factors for leptospirosis, especially in geographic areas not considered at high risk and in groups not in occupations traditionally linked to the disease. AD - World Health Organization/Food and Agriculture Organization Collaborating Centre for Reference and Research on Laptospirosis, Laboratory of Microbiology and Pathology, Brisbane, Queensland. PMID- 9079586 SO - Commun Dis Intell 1997 Jan 23;21(2):17-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 97158205 AU - Dhaliwal GS AU - Murray RD AU - Dobson H AU - Ellis WA TI - Effect of Leptospira interrogans serovar hardjo infection on progesterone concentrations in heifers. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*blood MH - Estrus/blood/*metabolism MH - Female MH - Pregnancy MH - Progesterone/*blood MH - Support, Non-U.S. Gov't MH - Weil's Disease/blood/*veterinary RN - 57-83-0 (Progesterone) PT - JOURNAL ARTICLE DA - 970415 DP - 1997 Jan 4 IS - 0042-4900 TA - Vet Rec PG - 19-20 SB - M CY - ENGLAND IP - 1 VI - 140 JC - XBS EM - 9706 AD - Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Leahurst, Neston, South Wirral. PMID- 9004477 SO - Vet Rec 1997 Jan 4;140(1):19-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] UI - 98002365 AU - Rioche M AU - Dubreuil P AU - Kouassi-Samgare A AU - Akran V AU - Nordmann P AU - Pillot J TI - [Incidence of sporadic hepatitis E in Ivory Coast based on still problematic serology] LA - Fre MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Comparative Study MH - Cote d'Ivoire/epidemiology MH - Cross-Sectional Studies MH - Diagnosis, Differential MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Hepatitis Antibodies/analysis MH - Hepatitis C/diagnosis/immunology MH - Hepatitis C Antibodies/analysis MH - Hepatitis E/diagnosis/*epidemiology/immunology MH - Human MH - IgG/analysis MH - Infant MH - Male MH - Middle Age RN - 0 (Hepatitis Antibodies) RN - 0 (Hepatitis C Antibodies) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 971114 DP - 1997 IS - 0042-9686 TA - Bull World Health Organ PG - 349-54 CY - SWITZERLAND IP - 4 VI - 75 JC - C80 AA - Author EM - 9801 AB - The first well-documented outbreak of viral hepatitis E in Africa was described in 1986 in Cote d'lvoire. Subsequently, no other outbreaks have been observed in the country. Cote d'lvoire therefore offers an excellent opportunity to evaluate the prevalence of sporadic viral hepatitis E in a country where the frequency of non-A, non-B, non-C viral hepatitis appears to be high. The study was carried out in Abidjan, the most populous city, and involved 111 hospitalized patients suffering from non-A, non-B and presumed non-C acute viral hepatitis. Screening for leptospirosis or a toxic etiology was carried out and the risk of including such patients eliminated. Diagnosis of viral hepatitis A was excluded from the absence of IgM anti-HAV antibodies. Patients with HBsAg and anti-HCV antibodies were not included in the study, although co-infection in asymptomatic HBV carriers or subsequent infection in patients who had recovered from a past HCV infection remained possible. There was a risk that some patients with late appearance of anti-HCV antibodies were included since PCR tests could not be performed. Cytomegalovirus or Epstein-Barr virus was not involved, since no specific IgMs against these viruses were detectable. Large discrepancies between the two commercial enzyme-linked immunosorbent assays (ELISAs) available for serological diagnosis of hepatitis E (Abbott and Genelabs) were observed. Among the 53 sera screened using both tests, only 20 gave positive results in both, and all such sera were confirmed using a domestic immunological test involving inhibition of labelled, well-documented anti-HEV-specific human IgG. Immunological confirmation was obtained for only half of the sera with discordant results in the commercial ELISAs. Full agreement between both commercial tests was observed for only 59% of the sera studied. The minimal incidence of sporadic viral hepatitis E among hospitalized patients in Abidjan with an acute hepatitis was estimated to be 27%. AD - Institut Pasteur de Cote d'lvoire, Service des Hepatites virales et des Retrovirus, Abidjan, Cote d'lvoire. PMID- 9377791 TT - Frequence de l'hepatite sporadique E en Cote d'Ivoire, vue au travers d'une serologie encore problematique. EA - A SO - Bull World Health Organ 1997;75(4):349-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 98017336 AU - Chandrasekaran S AU - Pankajalakshmi VV TI - Usefulness of dark field microscopy after differential centrifugation in the early diagnosis of leptospirosis in dog and its human contacts. LA - Eng MH - Adult MH - Animal MH - Blood/microbiology MH - Child MH - Dog Diseases/blood/*pathology/transmission/urine MH - Dogs MH - Female MH - Human MH - Leptospirosis/*transmission/*veterinary MH - Microscopy/*methods MH - Occupational Diseases/blood/*pathology MH - Postmortem Changes MH - Urine/cytology/microbiology MH - *Veterinary Medicine MH - *Zoonoses PT - JOURNAL ARTICLE DA - 971118 DP - 1997 Jan IS - 0019-5359 TA - Indian J Med Sci PG - 1-4 CY - INDIA IP - 1 VI - 51 JC - GJP AA - Author EM - 9801 AB - 1. We found leptospira in the blood of two out of three police dogs by dark field microscopic examination after high speed centrifugation. One dog had fever and the other was asymptomatic. Leptospira could not be seen in the urine of one police dog which died of jaundice. 11 out of 21 human contacts were found to be positive for leptospira after low speed centrifugation and 5 after high speed centrifugation. One child had jaundice and an another child had fever. Others had mild symptoms of headache to none. Dark field microscopy after differential centrifugation is useful in the early diagnosis of leptospirosis and thereby could prevent later complications like jaundice. AD - Institute of Microbiology, Madurai Medical College. PMID- 9355702 SO - Indian J Med Sci 1997 Jan;51(1):1-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97412486 AU - Stark KD AU - Frei-Staheli C AU - Frei PP AU - Pfeiffer DU AU - Danuser J AU - Audige L AU - Nicolet J AU - Strasser M AU - Gottstein B AU - Kihm U TI - [Frequency and cost of health problems in Swiss dairy cows and their calves (1993-1994)] LA - Ger MH - Animal MH - Animals, Newborn MH - Cattle MH - Cattle Diseases/*economics/*epidemiology MH - Cohort Studies MH - Communicable Diseases/economics/epidemiology/veterinary MH - Diarrhea/economics/epidemiology/veterinary MH - English Abstract MH - Female MH - Genital Diseases, Female/economics/epidemiology/veterinary MH - Incidence MH - Mastitis, Bovine/economics/epidemiology MH - Pneumonia/economics/epidemiology/veterinary MH - Pregnancy MH - Pregnancy Complications/economics/epidemiology/veterinary MH - Support, Non-U.S. Gov't MH - Switzerland/epidemiology PT - JOURNAL ARTICLE DA - 970916 DP - 1997 IS - 0036-7281 TA - Schweiz Arch Tierheilkd PG - 343-53 CY - SWITZERLAND IP - 8 VI - 139 JC - UE5 AA - Author EM - 9711 AB - Between July 1993 and July 1994 morbidity and management information related to dairy cows and their calves up to the age of 8 weeks were recorded in 113 randomly selected dairy herds. Also recorded were any costs incurred through disease and prevention. Blood and faeces were analysed with respect to selected pathogens. The health problems most frequently diagnosed in cows were reproductive and udder diseases. Calves suffered most often from diarrhea, omphalitis and pneumonia. The directly disease-related costs per cow-year on average amounted to CHF 139.44 and CHF 4.18 per calf. For prevention, farmers spent on average CHF 10.18 per cow-year. Results from the laboratory analyses indicate that in 68.1% of the farms antibodies against Leptospira hardjo and in 61.9% against Coxiella burnetii were detected. In 8.0% of the farms antibodies against Mycobacterium paratuberculosis were found. Antibodies against BVD virus was present in 99.4% of the farms. Cows from 63.7% farms were infected with gastrointestinal strongylids. Veterinary assistance was required on average 1.96 times per cow-year. In almost all reproductive and puerperal disease cases a veterinarian was consulted while lameness in the majority of cases was treated by the owner. The veterinary profession was hardly ever involved in disease prevention. AD - Institut fur Viruskrankbeiten und Immunoprophylaxe, Mittelhausern. PMID- 9297231 TT - Haufigkeit und Kosten von Gesundheitsproblemen bei Schweizer Milchkuhen und deren Kalbern (1993-1994). EA - A SO - Schweiz Arch Tierheilkd 1997;139(8):343-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97436969 AU - Valdes Gonzalez T AU - Gonzalez Perez M AU - Gonzalez Gonzalez M AU - Cabrera Arias RA AU - Munoz Carnago E AU - Lastre Gonzalez M AU - Sierra Gonzalez G TI - Quantification of bovine albumin fraction V in cellular antigens of antileptospirosical Cuban vaccine vaxSpiral. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis/immunology MH - Antigens, Bacterial/analysis/immunology MH - Bacterial Vaccines/*analysis/immunology MH - Cattle MH - Human MH - IgG/analysis/immunology MH - Immunoradiometric Assay MH - Leptospira/*immunology MH - Rabbits MH - Serum Albumin, Bovine/*analysis RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (IgG) RN - 0 (Serum Albumin, Bovine) PT - JOURNAL ARTICLE DA - 970929 DP - 1997 Autumn IS - 0188-0128 TA - Arch Med Res PG - 373-6 CY - MEXICO IP - 3 VI - 28 JC - BIC AA - Author EM - 9712 AB - A solid phase immunoradiometric assay (IRMA) for quantification of bovine albumin fraction V (Bov.Alb.FV) in antileptospirosical Cuban vaccine vaxSpiral is described in the present work. Anti-Bov.Alb.FV IgG raised against rabbit purified by affinity chromatography was used as first antibody. Anti-rabbit IgG labeled by Chloromine-T reaction was used as a tracer and the method has demonstrated to be sensitive with high intra- and inter-assay reproducibility. Eight lots of vaccinal antigens were evaluated and in all of the cases, the bovine albumin fraction V concentration was lower than 1 microgram/mL, as the World Health Organization (WHO) establishes. This IRMA is a simple and sensitive assay and could be used as control method for all human vaccines that use Bov.Alb.FV in their production process, even cellular vaccines. AD - Finlay Institute, La Habana, Cuba. PMID- 9291633 SO - Arch Med Res 1997 Autumn;28(3):373-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97424079 AU - Sakumoto M AU - Sakuma S AU - Kumazawa I TI - [Spirochetosis] LA - Jpn MH - Human MH - Kidney Diseases/*etiology MH - Leptospirosis MH - Lyme Disease MH - *Spirochaetales Infections MH - Syphilis PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 971114 DP - 1997 TA - Ryoikibetsu Shokogun Shirizu PG - 668-71 CY - JAPAN IP - 17 Pt 2 JC - CAY EM - 9801 AD - Department of Urology, Faculty of Medicine, Kyushu University. RF - 19 PMID- 9278021 SO - Ryoikibetsu Shokogun Shirizu 1997;(17 Pt 2):668-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97301422 AU - Mel'nik GV AU - Avdeeva MG AU - Piskunov OV TI - [The importance of myoglobin in the pathogenesis of leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Aged MH - Antibodies, Bacterial/blood MH - Blood Donors MH - Case Report MH - Comparative Study MH - English Abstract MH - Female MH - Human MH - Jaundice/diagnosis/etiology/metabolism MH - Leptospira interrogans/immunology MH - Male MH - Middle Age MH - Myoglobin/*analysis MH - Severity of Illness Index MH - Weil's Disease/diagnosis/*etiology/metabolism RN - 0 (Antibodies, Bacterial) RN - 0 (Myoglobin) PT - JOURNAL ARTICLE DA - 970703 DP - 1997 IS - 0040-3660 TA - Ter Arkh PG - 69-72 SB - M CY - RUSSIA IP - 4 VI - 69 JC - VLU AA - Author EM - 9709 AB - Measurements were made of serum and urine myoglobin in 48 patients with leptospiral jaundice (LJ) and 56 patients with various acute infections. At the height of LJ blood myoglobin level reached 28.96 +/- 4.3 micrograms/l (normal concentration 0.315 +/- 0.002 microgram/l). Compared to acute pneumonia, acute viral hepatitis, tonsillitis, erysipelas, diphtheria, health values, the ratio of serum myoglobin to urine myoglobin in leptospirosis made up 45.25 against 5.4, 4.8, 6.8, 3.7, 1.8 and 1.3, respectively. A relationship was found between concentrations of myoglobin, bilirubin, creatinine in the blood and leptospirosis severity. Elevation of serum myoglobin as a manifestation of specific myositis is pathognomic for leptospirosis and contributes to the onset of acute renal failure and disturbance of bilirubin metabolism. Quantitation of blood myoglobin may be helpful as an additional test for leptospirosis severity. PMID- 9213968 TT - Znachenie mioglobina v patogeneze leptospiroza. EA - A SO - Ter Arkh 1997;69(4):69-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 97295160 AU - Mittermayer H TI - [Community-acquired pneumonia--current status of pathogen diagnosis] LA - Ger MH - Bacteriological Techniques MH - Community-Acquired Infections/*diagnosis/microbiology MH - Diagnosis, Differential MH - English Abstract MH - Human MH - Pneumonia, Bacterial/*diagnosis/microbiology MH - Polymerase Chain Reaction PT - JOURNAL ARTICLE DA - 970630 DP - 1997 IS - 0303-8173 TA - Acta Med Austriaca PG - 8-9 SB - M CY - AUSTRIA IP - 1 VI - 24 JC - 0Y2 AA - Author EM - 9709 AB - Procedures for the microbiological diagnosis of acute community- acquired pneumonia are based on the expected pathogens. Although a great variety of microorganisms are able to cause community-acquired pneumonia only a few pathogens play an important role in daily practice. The most important investigations are blood cultures and sputum cultures to detect bacteria like pneumococci, Haemophilus influenzae and Staphylococcus aureus as well as antibody tests for Mycoplasma pneumonia and Chlamydia pneumonia. According to anamnesis and clinic presentation tests such as for Legionella or viruses have to be added. Sometimes also rare pathogens have to be considered such as Coxiella burnetii, Leptospira, Hantaviruses, cryptococci or Chlamydia psittaci. The standard procedure for diagnosis of tuberculosis is the microscopical examination and the standardized culture in liquid and on solid media. Amplification methods such as PCR are also useful for a rapid diagnosis. However, the application of amplification procedures alone without culture is not recommended. AD - Institut fur Medizinische Mikrobiologie und Hygiene, A.o. Krankenhauses der Elisabethinen, Linz. PMID- 9206930 TT - Ambulant erworbene Pneumonie--Aktueller Stand der Erregerdiagnostik. EA - A SO - Acta Med Austriaca 1997;24(1):8-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 97276487 AU - Isogai E AU - Hirose K AU - Kimura K AU - Hayashi S AU - Kubota T AU - Fujii N AU - Isogai H TI - Role of platelet-activating-factor (PAF) on cellular responses after stimulation with leptospire lipopolysaccharide. LA - Eng MH - Animal MH - Cell Adhesion MH - Cell Aggregation MH - Comparative Study MH - Endothelium, Vascular/immunology MH - Human MH - Leptospira interrogans/*immunology MH - Lipopolysaccharides/*immunology MH - Platelet Activating Factor/*immunology MH - Platelet Aggregation MH - Rabbits MH - Shock, Septic/immunology RN - 0 (Lipopolysaccharides) RN - 0 (Platelet Activating Factor) PT - JOURNAL ARTICLE DA - 970702 DP - 1997 IS - 0385-5600 TA - Microbiol Immunol PG - 271-5 SB - M CY - JAPAN IP - 3 VI - 41 JC - MX7 AA - Author EM - 9709 AB - Leptospire lipopolysaccharide (LPS) stimulated the adherence of polymorphonuclear neutrophils (PMNs) to human umbilical vein endothelial cells (HUVEC). Enhanced PMN adherence in response to leptospire LPS can be mediated by platelet-activator-factor (PAF), because a PAF antagonist reduced adherence. Leptospire LPS also induced the adherence platelets or U937. The second experiment involved leptospire LPS elicited platelet aggregation in a PMN-platelet mixture, because leptospire LPS stimulated human PMN but not the human platelets. The platelet response was observed only in the mixture system and was inhibited by a PAF antagonist. PAF could be an important pathogenic factor in human leptospirosis. AD - Department of Preventive Dentistry, Health Sciences University of Hokkaido, Japan. PMID- 9130240 SO - Microbiol Immunol 1997;41(3):271-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97271526 AU - Douglin CP AU - Jordan C AU - Rock R AU - Hurley A AU - Levett PN TI - Risk factors for severe leptospirosis in the parish of St. Andrew, Barbados [letter] LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Barbados/epidemiology MH - Case-Control Studies MH - Child MH - Dogs MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Rain MH - Retrospective Studies MH - Risk Factors MH - Seasons PT - LETTER DA - 970520 DP - 1997 Jan-Mar IS - 1080-6040 TA - Emerg Infect Dis PG - 78-80 SB - M CY - UNITED STATES IP - 1 VI - 3 JC - COD EM - 9707 PMID- 9126452 SO - Emerg Infect Dis 1997 Jan-Mar;3(1):78-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97269809 AU - Parma AE AU - Sanz ME AU - Lucchesi PM AU - Mazzonelli J AU - Petruccelli MA TI - Detection of an antigenic protein of Leptospira interrogans which shares epitopes with the equine cornea and lens. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis/immunology MH - Bacterial Proteins/immunology MH - Blotting, Western/veterinary MH - Cornea/*immunology MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel/veterinary MH - Epitopes/*immunology MH - Horses/*immunology MH - Immunohistochemistry MH - Lens, Crystalline/*immunology MH - Leptospira interrogans/*immunology/ultrastructure MH - Microscopy, Electron/veterinary MH - Rabbits MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 970515 DP - 1997 Jan IS - 1090-0233 TA - Vet J PG - 75-9 CY - ENGLAND IP - 1 VI - 153 JC - CS5 AA - Author EM - 9707 AB - A protein epitope which is involved in an antigenic relationship between equine ocular tissues and Leptospira interrogans was detected in homogenates of the bacterium. The antigenic determinant was harboured on a peptide structure which was shown to be sensitive to the action of denaturing and reducing agents by means of Western blotting. The outer surface of the leptospires appeared to be free of this epitope as was proved by dot-blot and electron microscopic studies. AD - Department of Animal Health, Immunochemistry, Faculty of Veterinary Science, University of the Centre, Tandil, Argentina. PMID- 9125359 SO - Vet J 1997 Jan;153(1):75-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97177819 AU - Sting R AU - Nagel C AU - Steng G TI - [Significance of causes of infectious abortion in sheep flocks in northern Baden-Wurttemberg with special reference to Chlamydia psittaci] LA - Ger MH - Abortion, Veterinary/*epidemiology/*microbiology MH - Animal MH - Brucellosis/epidemiology/veterinary MH - *Chlamydia psittaci MH - English Abstract MH - Female MH - Germany/epidemiology MH - Leptospirosis/epidemiology/veterinary MH - Ornithosis/epidemiology/*veterinary MH - Pregnancy MH - Salmonella Infections, Animal/*epidemiology MH - Sheep MH - *Sheep Diseases PT - JOURNAL ARTICLE DA - 970410 DP - 1997 Jan IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 5-11 CY - GERMANY IP - 1 VI - 110 JC - 9Q8 AA - Author EM - 9706 AB - Investigations on the reasons of infectious abortion cases in sheep flocks in northern parts of Baden-Wuerttemberg eludicate the wide- spreading of Chlamydia psittaci (C. psittaci) and its significance as the most frequent cause of abortions in sheep. Another important pathogen agent causing abortions is Salmonella abortus ovis (S. abortus ovis) which could be demonstrated by using a serological ELISA test. A less important role than C. psittaci and S. abortus ovis plays Coxiella burnetii in abortion of sheep. A high prevalence of Toxoplasma gondii and border disease infections in sheep flocks could be revealed by serological studies, too. Statistical evaluations of the obtained results demonstrate a significantly increased number of positively reacting female sheep in flocks suffering from abortions in comparison to those deriving from flocks devoid of abortion cases. Serological studies on leptospirosis and brucellosis exclude a participation of these pathogen agents in abortion cases in the investigated flocks at present. The significance of zoonosis originated from sheep is emphasized. AD - Staatliches Tierarztliches Untersuchungsamt Stuttgart. PMID- 9092464 TT - Die Bedeutung infektioser Abortursachen in Schafherden im nordlichen Baden-Wurttemberg unter besonderer Berucksichtigung von Chlamydia psittaci. EA - A SO - Berl Munch Tierarztl Wochenschr 1997 Jan;110(1):5-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 97216907 AU - Subich MG AU - Avdeeva MG AU - Moisova DL TI - [Relationship between cytochemical activity of leukocytes and autorosette formation phenomenon and its clinical significance in patients with leptospirosis] LA - Rus MH - Acid Phosphatase/blood MH - Adolescence MH - Adult MH - Aged MH - Alkaline Phosphatase/blood MH - Comparative Study MH - English Abstract MH - Female MH - Histocytochemistry MH - Human MH - Leukocytes/*immunology/metabolism MH - Male MH - Middle Age MH - *Rosette Formation MH - Weil's Disease/diagnosis/*immunology/metabolism RN - EC 3.1.3.1 (Alkaline Phosphatase) RN - EC 3.1.3.2 (Acid Phosphatase) PT - JOURNAL ARTICLE DA - 970408 DP - 1997 Jan IS - 0869-2084 TA - Klin Lab Diagn PG - 13-4 CY - RUSSIA IP - 1 JC - B17 AA - Author EM - 9706 AB - The content of autorosettes in the peripheral blood forming from red cells round neutrophils and monocytes was found increased during the acute period of icterohemorrhagic leptospirosis. Autorosette-forming cells are characterized by a high activity of alkaline and acid phosphatases and low NBT-test values. The content of autorosettes directly correlates with the disease severity, bilirubin level, and presence of anemia. Assessment of autorosette-forming cells in patients with leptospirosis may be used as an additional test for evaluating the severity of intoxication, disease course, and for predicting the complications and disease outcome. PMID- 9091125 TT - Vzaimosviaz' tsitokhimicheskoi aktivnosti leikotsitov s fenomenom autorozetkoobrazovaniia i ego klinicheskoe znachenie u bol'nykh leptospirozom. EA - A SO - Klin Lab Diagn 1997 Jan;(1):13-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97189436 AU - Ciceroni L AU - Bartoloni A AU - Pinto A AU - Guglielmetti P AU - Valdez Vasquez C AU - Gamboa Barahona H AU - Roselli M AU - Giannico F AU - Paradisi F TI - Serological survey of leptospiral infections in sheep, goats and dogs in Cordillera province, Bolivta. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Bolivia/epidemiology MH - Dogs MH - Goats MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology/*veterinary MH - Prevalence MH - Seroepidemiologic Methods MH - Sheep RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 970430 DP - 1997 Jan IS - 1121-7138 TA - New Microbiol PG - 77-81 SB - M CY - ITALY IP - 1 VI - 20 JC - CGC AA - Author EM - 9707 AB - A serological survey for antibodies to Leptospira spp. was conducted on sheep, goat and dog serum samples collected in three localities in Cordillera province in the southern part of the Santa Cruz Department (Bolivia) in 1992. A total of 98 sheep, 218 goats and 43 dogs were tested against 29 leptospiral serovars using the microscopic agglutination test. At the time of blood collection all of the examined animals appeared healthy and presented no clinical sign suggestive of leptospirosis. Antibody prevalences, as determined by positive results at a 1:100 dilution or higher, was 14.3% in sheep, 19.7% in goats, and 14.0% in dogs. Agglutinins against six serovars (poi. shermani, pomona, canicola, javanica, djasiman) were found in positive animals. The highest serological prevalence in sheep and goats was recorded for serovar poi, followed by pomona in sheep and shermani in goats. Titres to shermani were the commonest in dogs. The results of this survey indicate that leptospiral infection is common in south-east Bolivia and that serovars of several serogroups concur in the etiology. AD - Department of Bacteriology and Medical Mycology, Istituto Superiore di Santia, Rome, Italy PMID- 9037672 SO - New Microbiol 1997 Jan;20(1):77-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 97179404 AU - Gese EM AU - Schultz RD AU - Johnson MR AU - Williams ES AU - Crabtree RL AU - Ruff RL TI - Serological survey for diseases in free-ranging coyotes (Canis latrans) in Yellowstone National Park, Wyoming. LA - Eng MH - Adenoviruses, Canine/immunology MH - Animal MH - Antibodies, Bacterial/blood MH - Antibodies, Viral/blood MH - Bacterial Infections/epidemiology/*veterinary MH - Brucella/immunology MH - Brucellosis/epidemiology/veterinary MH - *Carnivora MH - Disease Reservoirs MH - Distemper/epidemiology MH - Distemper Virus, Canine/immunology MH - Female MH - Francisella tularensis/immunology MH - Hepatitis, Infectious Canine/epidemiology MH - Male MH - Parvoviridae Infections/epidemiology/veterinary MH - Parvovirus, Canine/immunology MH - Plague/epidemiology/veterinary MH - Prevalence MH - Support, Non-U.S. Gov't MH - Tularemia/epidemiology/veterinary MH - Virus Diseases/epidemiology/*veterinary MH - Wyoming/epidemiology MH - Yersinia pestis/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 971106 DP - 1997 Jan IS - 0090-3558 TA - J Wildl Dis PG - 47-56 SB - M CY - UNITED STATES IP - 1 VI - 33 JC - KEM AA - Author EM - 9801 AB - From October 1989 to June 1993, we captured and sampled 110 coyotes (Canis latrans) for various diseases in Yellowstone National Park, Wyoming (USA). Prevalence of antibodies against canine parvovirus (CPV) was 100% for adults (> 24 months old), 100% for yearlings (12 to 24 months old), and 100% for old pups (4 to 12 months old); 0% of the young pups (< 3 months old) had antibodies against CPV. Presence of antibodies against canine distemper virus (CDV) was associated with the age of the coyote, with 88%, 54%, 23%, and 0% prevalence among adults, yearlings, old pups, and young pups, respectively. Prevalence of CDV antibodies declined over time from 100% in 1989 to 33% in 1992. The prevalence of canine infectious hepatitis (ICH) virus antibodies was 97%, 82%, 54%, and 33%, for adults, yearlings, old pups, and young pups, respectively. The percentage of coyotes with ICH virus antibodies also declined over time from a high of 100% in 1989 to 31% in 1992, and 42% in 1993. Prevalence of antibodies against Yersinia pestis was 86%, 33%, 80%, and 7%, for adults, yearlings, old pups, and young pups, respectively, and changed over time from 57% in 1991 to 0% in 1993. The prevalence of antibodies against Francisella tularensis was 21%, 17%, 10%, and 20%, for adults, yearlings, old pups, and young pups, respectively. No coyotes had serologic evidence of exposure to brucellosis, either Brucella abortus or Brucella canis. No coyotes were seropositive to Leptospira interrogans (serovars canicola, hardjo, and icterohemorrhagiae). Prevalence of antibodies against L. interrogans serovar pomona was 7%, 0%, 0%, and 9%, for adults, yearlings, old pups, and young pups, respectively. Antibodies against L. interrogans serovar grippotyphosa were present in 17% of adults and 0% of yearlings, old pups, and young pups. Many infectious canine pathogens (CPV, CDV, ICH virus) are prevalent in coyotes in Yellowstone National Park, with CPV influencing coyote pup survival during the first 3 months of life; eight of 21 transmitted pups died of CPV infection in 1992. The potential impact of these canine pathogens on wolves (C. lupus) reintroduced to Yellowstone National Park remains to be documented. AD - Department of Wildlife Ecology, University of Wisconsin, Madison 53706, USA. PMID- 9027690 SO - J Wildl Dis 1997 Jan;33(1):47-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 97171238 AU - Kim YG AU - Jeon DY AU - Yang MK TI - Superoxide dismutase activity and lipid peroxidation in the liver of guinea pig infected with Leptospira interrogans. LA - Eng MH - Animal MH - Guinea Pigs MH - *Lipid Peroxidation MH - Liver/*enzymology/microbiology/pathology MH - Mice MH - Microscopy, Electron MH - Superoxide Dismutase/*metabolism MH - Thiobarbituric Acid Reactive Substances/analysis MH - Weil's Disease/*enzymology/pathology RN - EC 1.15.1.1 (Superoxide Dismutase) RN - 0 (Thiobarbituric Acid Reactive Substances) PT - JOURNAL ARTICLE DA - 970605 DP - 1997 Jan IS - 1071-5762 TA - Free Radic Res PG - 1-6 SB - M CY - SWITZERLAND IP - 1 VI - 26 JC - BW3 AA - Author EM - 9708 AB - Superoxide dismutase (SOD) activity and the degree of lipid peroxidation were studied over a two week period in guinea pigs infected with Leptospira interrogans derived from wild mice. The total SOD activity in infected host liver increased by four-fold two days after infection; this was followed by a 20% decrease resulting in levels comparable to normal, uninfected liver. During the period of decreasing SOD activity after day two, the levels of TBA-reactive material (TBARS) are increased by three-fold in infected guinea pig, liver, compared to uninfected liver. The results indicate that SOD attenuates intracellular superoxide-mediated toxic effects in guinea pigs infected with L. interrogans. In addition, electron microscopy structure demonstrates correlated pathogenic shrinkage of mitochondrial and Kupffer cell structures. AD - Department of Biological Science, College of Natural Sciences, Chosun University, Kwangju, Korea. PMID- 9018467 SO - Free Radic Res 1997 Jan;26(1):1-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [98 medline neighbors] UI - 97161585 AU - Masri SA AU - Nguyen PT AU - Gale SP AU - Howard CJ AU - Jung SC TI - A polymerase chain reaction assay for the detection of Leptospira spp. in bovine semen. LA - Eng MH - Animal MH - Cattle MH - DNA Primers MH - Genome, Bacterial MH - Kidney/microbiology MH - Leptospira/genetics/*isolation & purification MH - Leptospirosis/*diagnosis/urine MH - Male MH - Polymerase Chain Reaction/*methods MH - Restriction Mapping MH - Semen/*microbiology RN - 0 (DNA Primers) PT - JOURNAL ARTICLE DA - 970603 DP - 1997 Jan IS - 0830-9000 TA - Can J Vet Res PG - 15-20 SB - M CY - CANADA IP - 1 VI - 61 JC - CKL AA - Author EM - 9708 AB - A rapid and specific method for the detection of pathogenic Leptospira spp. in bovine semen using the polymerase chain reaction (PCR) is described. The primers used were derived from an EcoR1/BamH1 fragment that hybridized strongly to chromosomal DNA from the hardjobovis serovar. Three different extraction methods were evaluated in this study: phenol-chloroform extraction method, proteinase K (PK) in 1% SDS, followed by phenol-chloroform, and phenol-chloroform followed by 1% cetyltrimethylammonium bromide (CTAB). A PCR product of approximately 500 base pairs (bp) in length was obtained when DNA from pure Leptospira culture was used as a template for PCR, regardless of the DNA extraction method used. The product was consistent with that predicted from the gene sequence. However, in semen seeded in vitro, as well as in semen from infected bulls, a PCR product was obtained only when the leptospiral DNA was extracted from the specimen using the CTAB method. In contrast, other methods used for DNA extraction did not generate suitable templates for the PCR procedure. This is the first PCR protocol developed to detect Leptospira in bovine semen. The PCR protocol provided a direct and unequivocal demonstration that Leptospira can be detected in semen of infected animals. The CTAB method was also used successfully in detecting Leptospira in the urine of infected animals. The PCR procedure was shown to be more sensitive than either the fluorescent antibody test (FAT) or culture for detecting the organism in urine. AD - Animal Diseases Research Institute, Agriculture and Agri-Food Canada, Lethbridge, Alberta. PMID- 9008795 SO - Can J Vet Res 1997 Jan;61(1):15-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 97123670 AU - Letocart M AU - Baranton G AU - Perolat P TI - Rapid identification of pathogenic Leptospira species (Leptospira interrogans, L. borgpetersenii, and L. kirschneri) with species- specific DNA probes produced by arbitrarily primed PCR. LA - Eng MH - *Bacterial Typing Techniques MH - *DNA Probes MH - DNA, Bacterial/*analysis MH - Human MH - Leptospira/*classification/isolation & purification MH - Leptospira interrogans/*classification MH - Polymerase Chain Reaction/methods MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 970319 DP - 1997 Jan IS - 0095-1137 TA - J Clin Microbiol PG - 248-53 SB - M CY - UNITED STATES IP - 1 VI - 35 JC - HSH AA - Author EM - 9705 AB - Arbitrarily primed PCR (AP-PCR) assays can be used to discriminate between species of Leptospira. Comparative analysis of the fingerprints obtained from representative sets of serovar reference strains of Leptospira interrogans sensu stricto, L. borgpetersenii, and L. kirschneri and the reference strains of the other Leptospira spp. revealed species-specific DNA fragments. These species-specific sequences were reamplified in order to produce digoxigenin-11-dUTP- labeled genomic DNA probes that could be used to identify Leptospira species. Three probes (specific for L. interrogans sensu stricto, L. borgpetersenii, and L. kirschneri) were selected and tested with 72 representative serovar reference strains, all of which had previously been studied by DNA-DNA hybridization. The two techniques were in general agreement, and hybridization with AP-PCR-derived probes was shown to be a useful approach for rapid species determination of leptospires, without the prior need for DNA sequence information. These nonradioactive probes can be used to identify Leptospira species in nonspecialized laboratories, and this should contribute to a better knowledge of the molecular epidemiology of leptospirosis. AD - Laboratoire des Leptospires, Institut Pasteur, Noumea, Nouvelle- Caledonie, France. PMID- 8968917 SO - J Clin Microbiol 1997 Jan;35(1):248-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [168 medline neighbors] UI - 97123639 AU - Gussenhoven GC AU - van der Hoorn MA AU - Goris MG AU - Terpstra WJ AU - Hartskeerl RA AU - Mol BW AU - van Ingen CW AU - Smits HL TI - LEPTO dipstick, a dipstick assay for detection of Leptospira-specific immunoglobulin M antibodies in human sera. LA - Eng MH - Antibodies, Bacterial/*blood/immunology MH - Human MH - IgM/*blood MH - Immunoenzyme Techniques MH - Leptospira/*immunology/isolation & purification MH - Leptospirosis/blood/*microbiology RN - 0 (Antibodies, Bacterial) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 970319 DP - 1997 Jan IS - 0095-1137 TA - J Clin Microbiol PG - 92-7 SB - M CY - UNITED STATES IP - 1 VI - 35 JC - HSH AA - Author EM - 9705 AB - We studied a dipstick assay for the detection of Leptospira-specific immunoglobulin M (IgM) antibodies in human serum samples. A high degree of concordance was observed between the results of the dipstick assay and an IgM enzyme-linked immunosorbent assay (ELISA). Application of the dipstick assay for the detection of acute leptospirosis enabled the accurate identification, early in the disease, of a high proportion of the cases of leptospirosis. Analysis of a second serum sample is recommended, in order to determine seroconversion or increased staining intensity. All serum samples from the patients who were confirmed to be positive for leptospirosis by either a positive microscopic agglutination test or a positive culture but were found to be negative by the dipstick assay were also judged to be negative by the IgM ELISA or revealed borderline titers by the IgM ELISA. Some cross-reactivity was observed for sera from patients with diseases other than leptospirosis, and this should be taken into account in the interpretation of test results. The dipstick assay is easy to perform, can be performed quickly, and requires no electricity or special equipment, and the assay components, a dipstick and a staining reagent, can be stored for a prolonged period without a loss of reactivity, even at elevated temperatures. AD - Department of Biomedical Research, Royal Tropical Institute, AZ Amsterdam, The Netherlands. PMID- 8968886 SO - J Clin Microbiol 1997 Jan;35(1):92-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 97174690 AU - Stanko M AU - Prokopcakova H AU - Fricova J AU - Pet'ko B TI - [Leptospira antibodies in small mammals in Eastern Slovakia] LA - Slo MH - Animal MH - Antibodies, Bacterial/*analysis MH - English Abstract MH - Leptospira/*immunology MH - Muridae/*microbiology MH - Slovakia RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 970303 DP - 1996 Dec IS - 0375-8427 TA - Vet Med (Praha) PG - 373-7 CY - CZECH REPUBLIC IP - 12 VI - 41 JC - XBP AA - Author EM - 9705 AB - During the five years (1991-1995) mostly free living small mammals were examined serologically for the presence of antibodies to leptospira. Serological examinations were used by Kmety and Bakoss (1978). Altogether, 2493 individuals of 22 species were examined, an important part of host material (69.6%) was caught in two lowland areas which are intensively cultivated landscapes (East Slovakian Lowland and Kosicka kotlina basin). The remaining material comes from submontane areas with less agricultural activities. Apodemus flavicollis, A. agrarius, Clethrionomys glareolus were the most frequently examined species. Antibodies to leptospira were demonstrated in 123 mammals (i. e. in 5.0% of hosts) of eleven species. The highest percentage of positive hosts were recorded in 1993 (8.8%) and the lowest (2.6%) in 1995, but the examined samples were different in size and structure of host species. In six most dominant species higher values of antibodies to leptospira were detected in Microtus arvalis (9.2%), followed by Apodemus flavicollis (5.6%), A. agrarius (5.4%) and A. microps (4.9%). The lowest values were found in Clethrionomys glareolus (2.5%) and Sorex araneus (2.3%). In examined hosts we found antibodies to six serovars of leptospira. The most frequently observed antibodies were to leptospira of the serovar L. grippotyphosa (63.2%) and leptospira of the serovar L. sejroe (26.4%). We recorded nonsignificant differences between the values of prevalence to antibodies in small mammal communities from lowland and submontane areas, resp. Our results confirmed differences in the leptospira serovar structure in small mammals of Bohemia and Slovakia, they were connected with different historical development of both areas. Comparing our results with previous examinations (about 20 years ago) in small mammals from eastern Slovakia, a decline of positivity and lower number of leptospira serovars were recorded. AD - Institute of Zoology of the Slovak Academy of Sciences, Kosice, Slovak Republic. stankom@saske.sk PMID- 9045500 TT - Vyskyt protilatok proti leptospiram u drobnych cicavcov na vychodnom slovensku. EA - A SO - Vet Med (Praha) 1996 Dec;41(12):373-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 97171463 AU - Teal TH AU - Chapman M AU - Guillemette T AU - Margulis L TI - Free-living spirochetes from Cape Cod microbial mats detected by electron microscopy. LA - Eng MH - Massachusetts MH - Microscopy, Electron MH - Seawater MH - Spirochaetales/*isolation & purification/ultrastructure MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 970417 DP - 1996 Dec IS - 0213-4101 TA - Microbiologia PG - 571-84 SB - M CY - SPAIN IP - 4 VI - 12 JC - AIF AA - Author EM - 9706 AB - Spirochetes from microbial mats and anaerobic mud samples collected in salt marshes were studied by light microscopy, whole mount and thin section transmission electron microscopy. Enriched in cellobiose- rifampin medium, selective for Spirochaeta bajacaliforniensis, seven distinguishable spirochete morphotypes were observed. Their diameters ranged from 0.17 micron to > 0.45 micron. Six of these morphotypes came from southwest Cape Cod, Massachusetts: five from Microcoleus-dominated mat samples collected at Sippewissett salt marsh and one from anoxic mud collected at School Street salt marsh (on the east side of Eel Pond). The seventh morphotype was enriched from anoxic mud sampled from the north central Cape Cod, at the Sandy Neck salt marsh. Five of these morphotypes are similar or identical to previously described spirochetes (Leptospira, Spirochaeta halophila, Spirochaeta bajacaliforniensis, Spirosymplokos deltaeiberi and Treponema), whereas the other two have unique features that suggest they have not been previously described. One of the morphotypes resembles Spirosymplokos deltaeiberi (the largest free-living spirochete described), in its large variable diameter (0.4-3.0 microns), cytoplasmic granules, and spherical (round) bodies with composite structure. This resemblance permits its tentative identification as a Sippewissett strain of Spirosymplokos deltaeiberi. Microbial mats samples collected in sterile Petri dishes and stored dry for more than four years yielded many organisms upon rewetting, including small unidentified spirochetes in at least 4 out of 100 enrichments. AD - Department of Biology, University of Massachusetts, Amherst 01003-5018, USA. PMID- 9018691 SO - Microbiologia 1996 Dec;12(4):571-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 97150663 AU - Lucht F AU - Lafond P AU - Bertrand JC TI - [Myopericarditis and auricular fibrillation disclosing septicemic leptospirosis (letter; comment)] LA - Fre MH - Atrial Fibrillation/diagnosis/etiology MH - Human MH - Leptospirosis/*blood/complications/diagnosis MH - Myocarditis/complications/diagnosis/*etiology MH - Pericarditis/complications/diagnosis/*etiology MH - Septicemia/*diagnosis/etiology/microbiology PT - COMMENT PT - LETTER DA - 970123 DP - 1996 Nov 23 IS - 0755-4982 TA - Presse Med PG - 1805 SB - X SB - M CY - FRANCE IP - 36 VI - 25 JC - PMT EM - 9703 CM - Comment on: Presse Med 1996 Mar 30;25(11):555 RO - M:CNR PMID- 8999426 LR - 970414 TT - Myopericardite et fibrillation auriculaire revelatrices d'une leptospirose septicemique. SO - Presse Med 1996 Nov 23;25(36):1805 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 97037752 AU - Vinetz JM AU - Glass GE AU - Flexner CE AU - Mueller P AU - Kaslow DC TI - Sporadic urban leptospirosis. LA - Eng MH - Adult MH - Animal MH - Antibodies, Bacterial/analysis MH - Baltimore/epidemiology MH - Disease Vectors MH - DNA, Bacterial/analysis MH - Female MH - Human MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/transmission MH - Male MH - Polymerase Chain Reaction MH - Rats/microbiology/urine MH - Risk Factors MH - Support, Non-U.S. Gov't MH - *Urban Health RN - 0 (Antibodies, Bacterial) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 961119 DP - 1996 Nov 15 IS - 0003-4819 TA - Ann Intern Med PG - 794-8 SB - A SB - M SB - X CY - UNITED STATES IP - 10 VI - 125 JC - 5A6 AA - Author EM - 9701 AB - BACKGROUND: Surprisingly, many inner-city residents have antibodies to Leptospira interrogans. The manner in which these persons acquire this organism in the absence of recognized occupational, recreational, or epidemic risk factors is not known. OBJECTIVE: To study the epidemiology of patients with leptospirosis who acquired L. interrogans in inner-city Baltimore, Maryland. DESIGN: Epidemiologic investigation. SETTING: Inner-city university hospital. PATIENTS: Three inner-city residents who developed leptospirosis. MEASUREMENTS: Trapping rats in alleys where the patients may have acquired L. interrogans; polymerase chain reaction (PCR) analysis of patients serum and cerebrospinal fluid specimens and rat tissues to determine the presence of leptospiral DNA; and serologic testing of serum from patients and rats by microagglutination assay to confirm L. interrogans infection. RESULTS: Three patients developed leptospirosis after probable percutaneous exposure to rat (Rattus norvegicus) urine in Baltimore alleys. A PCR assay detected L. interrogans DNA in samples of body fluid obtained from the first two patients at presentation (one in cerebrospinal fluid, the other in serum). Results of PCR done on serum drawn from the third patient after antibiotic therapy began were negative. A microagglutination test showed that all patients had high levels of antibodies to the L. interrogans serogroup icterohaemorrhagiae. In 19 of 21 rats that were trapped in the alleys where the patients had sustained lacerations before illness developed, kidney or brain tissues were positive by PCR for the presence of L. interrogans. CONCLUSIONS: A population was discovered to be at risk for acquiring L. interrogans: urban residents who are sporadically exposed to rat urine in the inner city. Inner-city rats often carry L. interrogans. Polymerase chain reaction can quickly establish the diagnosis of leptospirosis and is useful for epidemiologic study. An endemic substrate for the transmission of the organism is present in inner-city Baltimore. Leptospirosis may become increasingly recognized in deteriorating inner cities in which rat populations are expanding. AD - Johns Hopkins School of Medicine, Baltimore, Maryland, USA. PMID- 8928985 SO - Ann Intern Med 1996 Nov 15;125(10):794-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 97211571 AU - Stoianova NA AU - Sergeiko LM AU - Sleptsova VI TI - [Immunological monitoring and the epidemiological characteristics of leptospirosis in Saint Petersburg] LA - Rus MH - Animal MH - Disease Reservoirs MH - Disease Vectors MH - Human MH - Leptospirosis/*epidemiology/immunology/transmission MH - Monitoring, Immunologic MH - Morbidity/trends MH - Russia/epidemiology MH - *Urban Population MH - Weil's Disease/epidemiology/immunology/transmission PT - JOURNAL ARTICLE DA - 970417 DP - 1996 Nov-Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 120-2 SB - M CY - RUSSIA IP - 6 JC - Y9O EM - 9706 PMID- 9103067 TT - Immunologicheskii monitoring i epidemiologicheskie osobennosti leptospiroza v Sankt-Peterburge. SO - Zh Mikrobiol Epidemiol Immunobiol 1996 Nov-Dec;(6):120-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [98 medline neighbors] UI - 97155391 AU - Bek M AU - Koppl H AU - Schwarzkopf G AU - Freudenberg N TI - [Weil's disease and necrotizing herpes pneumonia as the cause of death of a 39-year-old sewage drain worker] LA - Ger MH - Adult MH - Case Report MH - *Cause of Death MH - Disseminated Intravascular Coagulation/pathology MH - English Abstract MH - Herpes Simplex/*pathology MH - Human MH - Lung/pathology MH - Male MH - Necrosis MH - Occupational Diseases/*pathology MH - Pneumonia, Viral/*pathology MH - Sewage/microbiology MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 970328 DP - 1996 Nov IS - 0172-8113 TA - Pathologe PG - 471-6 SB - M CY - GERMANY IP - 6 VI - 17 JC - PLK AA - Author EM - 9706 AB - Acute leptospirosis in Europe (Weil's disease) is a rare and in more than 90% of the cases undiagnosed febrile, self-limited disease. We report the case of a 39-year-old sewerage worker, who was admitted to our hospital with fever, jaundice, pain in his calves and acute renal failure. Serology revealed elevated antibody titers against Leptospira canicola, L. icterhaemorrhagica and L. sejroe. The patient developed disseminated intravascular coagulation (DIC) with diffuse gastrointestinal bleeding due to thrombocytopenia. The ECG showed atrial fibrillation with irregularly irregular rhythm. Cardiac arrest developed, most likely due to hypoxia, with a drop in the blood pressure. Despite immediate resuscitation efforts the patient developed severe hypoxic brain damage and died a few days later. Autopsy disclosed histologic signs of a generalized leptospiral infection, signs of shock and within the lungs a necrotizing herpes simplex virus pneumonia causing the death of the patient. The virus pneumonia most probably was caused by retrograde canalicular dissemination of oral secretions since herpetic tracheitis and esophagitis were found and herpetic lesions were readily identified on the lips and tongue. A medical opinion asked for by the professional association having liability for occupational safety and insurance was given, the disease being recognized as an occupational disease. AD - Abteilung Allgemeine Pathologie, Universitat, Freiburg i. Br. PMID- 9082372 TT - Weil'sche Erkrankung und nekrotisierende Herpespneumonie als Todesursache bei einem 39 Jahre alt gewordenen Kanalarbeiter. EA - A SO - Pathologe 1996 Nov;17(6):471-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97215690 AU - Rajiv C AU - Manjuran RJ AU - Sudhayakumar N AU - Haneef M TI - Cardiovascular involvement in leptospirosis. LA - Eng MH - Atrial Fibrillation/etiology MH - Cardiovascular Diseases/diagnosis/*etiology MH - Echocardiography MH - Electrocardiography MH - Female MH - Heart Function Tests MH - Human MH - Hypotension/etiology MH - Leptospirosis/*complications/diagnosis MH - Male MH - Prognosis MH - Tachycardia/etiology PT - JOURNAL ARTICLE DA - 970410 DP - 1996 Nov-Dec IS - 0019-4832 TA - Indian Heart J PG - 691-4 CY - INDIA IP - 6 VI - 48 JC - GHR AA - Author EM - 9706 AB - Cardiovascular involvement was studied in 50 patients with serologically proved leptospirosis. Twelve (24%) patients had dyspnoea and 18 (36%) had transient hypotension during the illness. None of them had cardiac enlargement, development of new murmur or pericardial rub. Various electrocardiographic abnormalities occurred in 70 percent of patients. Atrial fibrillation was the most common major arrhythmia (14%). Conduction system abnormalities were seen in 36 percent of patients. T-wave changes were observed in 30 percent of patients. Left ventricular function as assessed by echocardiography and Doppler examination was normal. Three (6%) patients died due to renal failure. In conclusion, even though ECG abnormalities were frequently seen in leptospirosis, there was no data to support associated left ventricular dysfunction. Dyspnoea and hypotension occurring in patients of leptospirosis must be due to a noncardiac mechanism. AD - Department of Medicine, Medical College, Kottayam, Kerala. PMID- 9062020 SO - Indian Heart J 1996 Nov-Dec;48(6):691-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 97081581 AU - Tajiki H AU - Salomao R TI - Association of plasma levels of tumor necrosis factor alpha with severity of disease and mortality among patients with leptospirosis. LA - Eng MH - Adult MH - Human MH - Leptospirosis/blood/mortality/*physiopathology MH - Male MH - *Severity of Illness Index MH - Support, Non-U.S. Gov't MH - Tumor Necrosis Factor/*metabolism RN - 0 (Tumor Necrosis Factor) PT - JOURNAL ARTICLE DA - 970228 DP - 1996 Nov IS - 1058-4838 TA - Clin Infect Dis PG - 1177-8 SB - M CY - UNITED STATES IP - 5 VI - 23 JC - A4J EM - 9705 AD - Division of Infectious Diseases, Universidade Federal de Sao Paulo, Brazil. PMID- 8922824 SO - Clin Infect Dis 1996 Nov;23(5):1177-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 97062988 AU - Harkin KR AU - Gartrell CL TI - Canine leptospirosis in New Jersey and Michigan: 17 cases (1990-1995). LA - Eng MH - Amoxicillin/therapeutic use MH - Ampicillin/therapeutic use MH - Animal MH - Dog Diseases/*epidemiology/mortality/therapy MH - Dogs MH - Female MH - Fluid Therapy/veterinary MH - *Leptospira/classification MH - Leptospirosis/epidemiology/therapy/*veterinary MH - Male MH - Michigan/epidemiology MH - New Jersey/epidemiology MH - Penicillins/therapeutic use MH - Retrospective Studies MH - Survival Rate RN - 0 (Penicillins) RN - 26787-78-0 (Amoxicillin) RN - 69-53-4 (Ampicillin) PT - JOURNAL ARTICLE DA - 970121 DP - 1996 Nov-Dec IS - 0587-2871 TA - J Am Anim Hosp Assoc PG - 495-501 SB - M CY - UNITED STATES IP - 6 VI - 32 JC - B91 AA - Author EM - 9703 AB - The clinical, laboratory, and serological findings in 17 dogs with disease resulting from leptospiral infection were evaluated retrospectively. Acute renal failure was the most common syndrome, but cholestatic hepatic disease also was common. The most prevalent serovars identified were pomona, grippotyphosa, and autumnalis. Paired serology was available on 10 dogs. Aggressive fluid therapy in combination with ampicillin or amoxicillin resulted in a good survival rate. Canine leptospirosis may be more common than suspected, and paired serology often is necessary to confirm a diagnosis. AD - Oradell Animal Hospital, New Jersey 07649, USA. PMID- 8906726 SO - J Am Anim Hosp Assoc 1996 Nov-Dec;32(6):495-501 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97055509 AU - Parenti DM AU - Steinberg W AU - Kang P TI - Infectious causes of acute pancreatitis. LA - Eng MH - *Bacterial Infections MH - Human MH - Mycoses MH - Pancreatitis/*microbiology/*parasitology/VI MH - *Parasitic Diseases MH - *Virus Diseases PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, ACADEMIC DA - 970220 DP - 1996 Nov IS - 0885-3177 TA - Pancreas PG - 356-71 SB - M CY - UNITED STATES IP - 4 VI - 13 JC - PRS AA - Author EM - 9704 AB - A wide variety of infectious agents has been associated with acute pancreatitis. Strict diagnostic criteria were developed to assess with relationship between individual microorganisms and acute pancreatitis. Pathologic or radiologic evidence of pancreatitis associated with well- documented infection was noted with viruses (mumps, coxsackie, hepatitis B, cytomegalovirus, varicella-zoster virus, herpes simplex virus), bacteria (Mycoplasma, Legionella, Leptospira, Salmonella), fungi (Aspergillus), and parasites (Toxoplasma, Cryptosporidium, Ascaris). Clues to the infectious nature of pancreatitis lay in the characteristic signs and symptoms associated with the particular infectious agent. How often these agents are responsible for idiopathic pancreatitis is unclear. AD - Division of Infectious Diseases, George Washington University Medical Center, Washington, DC 20037, USA. RF - 238 PMID- 8899796 SO - Pancreas 1996 Nov;13(4):356-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 98023988 AU - Gulland FM AU - Koski M AU - Lowenstine LJ AU - Colagross A AU - Morgan L AU - Spraker T TI - Leptospirosis in California sea lions (Zalophus californianus) stranded along the central California coast, 1981-1994 [In Process Citation] LA - Eng DA - 971111 DP - 1996 Oct IS - 0090-3558 TA - J Wildl Dis PG - 572-80 SB - M CY - UNITED STATES IP - 4 VI - 32 JC - KEM AA - AUTHOR AB - Prevalence of leptospirosis was determined in California sea lions (Zalophus californianus) stranded live along the central California (USA) coast between January 1981 and December 1994. Clinical signs of renal disease were seen in 764 (33%) of 2338 animals examined; 545 (71%) of these 764 animals died, with similar gross lesions of nephritis. In silver impregnation stains of sections of formalin-fixed kidney, numerous loosely coiled spiral organisms were observed. Leptospira pomona kenniwicki was cultured from four kidney samples in 1991. Epizootics of leptospirosis occurred in 1984, 1988, 1991, and 1994, and were more common in the autumn, typically affecting juvenile males. In 1991 and 1994, 47 animals sampled had antibody titers to L. pomona greater than 1:3200. In 1992, 20 animals sampled were seronegative, and in 1993 three of 20 animals sampled had low titers to L. pomona. AD - Marine Mammal Center, Golden Gate National Recreation Area, Sausalito, California 94965, USA. RO - O:099 PMID- 9359054 SO - J Wildl Dis 1996 Oct;32(4):572-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 97139361 AU - Gorelova NB AU - Bellenger E AU - Postic D AU - Kovalevskii IuV TI - [Spontaneous mixed infection in rodents with Borrelia and Leptospira] LA - Rus MH - Animal MH - Borrelia/isolation & purification MH - Borrelia Infections/microbiology/*veterinary MH - Disease Reservoirs MH - English Abstract MH - Leptospira/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Microtinae/*microbiology MH - Rodent Diseases/*microbiology MH - Rodentia MH - Russia MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 970218 DP - 1996 Oct-Dec IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 53 CY - RUSSIA IP - 4 JC - M72 AA - Author EM - 9704 AB - This study was performed in a natural ITBB focus located in Perm' region of Russia. In 1993-1995, 73 root voles (Microtus oeconomus), collected in the forests, were examined by means of inoculation of internal organs on BSK-II medium. Borrelia were found in 13 animals (17.8%). According to the results in RLFP analysis 11 isolates were classified as B. garinii, 1 as B. afzelii and 1 as mixture of B. garinii and B. afzelii. In one case Leptospira, which was identified by PFGE analysis as grippotyphosa serovar, was found simultaneously with B. garinii in the BSK-II culture from urinary bladder. Our data testify to the fact of existence of mixed foci of leptospirosis and borreliosis. Moreover, one animal may serve as a reservoir host simultaneously of two different spirochetal agents. PMID- 9026677 TT - Spontannaia mikstazarazhennost' gryzuna borreliiami i leptospirami. EA - A SO - Med Parazitol (Mosk) 1996 Oct-Dec;(4):53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 97061285 AU - Deruaz D AU - Eid P AU - Deruaz J AU - Sempere A AU - Bourgouin C AU - Rodhain F AU - Perez-Eid C TI - Use of enzyme-labelled protein G assay for the detection of anti Borrelia burgdorferi antibodies in wild animal sera. LA - Eng MH - Animal MH - Animals, Wild/*immunology MH - Antibodies, Bacterial/*blood MH - Borrelia burgdorferi/*immunology MH - Deer/*immunology MH - Enzyme-Linked Immunosorbent Assay MH - France MH - Gene Amplification/methods MH - Hemagglutination Tests MH - IgG/*immunology MH - Lyme Disease/immunology/veterinary MH - Reproducibility of Results MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 970227 DP - 1996 Oct IS - 0392-2990 TA - Eur J Epidemiol PG - 515-9 SB - M CY - NETHERLANDS IP - 5 VI - 12 JC - ERE AA - Author EM - 9705 AB - A modified ELISA was developed for the detection of anti-Borrelia burgdorferi (Bb) IgG antibodies in wild animal sera based on an Enzyme- Labelled-protein G Assay (ELGA). Microplates were coated with an extract of Bb sensu stricto strain (SVI) as antigen. Specific antibodies of the serum samples were detected by a peroxidase-labelled- protein G. Using comparative immunodiagnosis by means of a passive hemagglutination test (HA), ELGA was tested on 82 roe-deer blood samples. A correlation was found between the two methods (r = 0.66). Good reproducibility of titers was observed by ELGA technique. A minimal cross-reactivity was discovered with Leptospira. ELGA could facilitate the recognition of specific antibodies in collections of wild animal sera. AD - Unite d' Ecologie des Systemes Vectoriels, Institut Pasteur, Paris; France. PMID- 8905315 SO - Eur J Epidemiol 1996 Oct;12(5):515-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 96434723 AU - Brown CA AU - Roberts AW AU - Miller MA AU - Davis DA AU - Brown SA AU - Bolin CA AU - Jarecki-Black J AU - Greene CE AU - Miller-Liebl D TI - Leptospira interrogans serovar grippotyphosa infection in dogs. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Cross Reactions MH - Dog Diseases/etiology/*microbiology MH - Dogs MH - Kidney Failure, Acute/etiology/*veterinary MH - Leptospira interrogans/classification/immunology/*isolation & purification MH - Leptospirosis/complications/microbiology/*veterinary MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 970113 DP - 1996 Oct 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1265-7 SB - M CY - UNITED STATES IP - 7 VI - 209 JC - HAV AA - Author EM - 9703 AB - Leptospirosis attributed to infection with serovar grippotyphosa was diagnosed in 11 dogs. In naturally and experimentally infected dogs, a stereotypic serologic response to infection with Leptospira serovar grippotyphosa was detected. Although the highest serum antibody titers developed against serovar grippotyphosa, most dogs also had lower titers against serovars bratislava and pomona. Acute renal failure was evident in 10 dogs. One dog died prior to initiation of treatment; the remaining 10 dogs were treated with antibiotics and fluids. Two dogs were euthanatized, 2 dogs recovered without clinical or biochemical evidence of residual renal dysfunction, and 6 dogs recovered but had varying degrees of renal insufficiency. Hepatic involvement appeared to be a minor component of the disease in these dogs. Our results indicate that Leptospira serovar grippotyphosa infection is an important problem in dogs and should be considered when evaluating a dog with renal failure. AD - Athens Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia, Athens 30602, USA. PMID- 8837647 SO - J Am Vet Med Assoc 1996 Oct 1;209(7):1265-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 97048660 AU - Dhaliwal GS AU - Murray RD AU - Dobson H AU - Montgomery J AU - Ellis WA TI - Effect of Leptospira interrogans serovar hardjo infection on milk yield in endemically infected dairy herds. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Lactation MH - Leptospira interrogans/*isolation & purification MH - Milk/*secretion MH - Support, Non-U.S. Gov't MH - Weil's Disease/*veterinary PT - JOURNAL ARTICLE DA - 970128 DP - 1996 Sep 28 IS - 0042-4900 TA - Vet Rec PG - 319-20 SB - M CY - ENGLAND IP - 13 VI - 139 JC - XBS EM - 9704 AD - Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Leahurst, Neston, South Wirral. PMID- 8893491 SO - Vet Rec 1996 Sep 28;139(13):319-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 97007425 AU - van de Wouw AJ AU - Buiting AG AU - van Boven WP AU - van der Heul C TI - [Rhabdomyolysis and kidney insufficiency in van Weil syndrome] LA - Dut MH - Adult MH - Case Report MH - English Abstract MH - Hemodialysis MH - Human MH - Kidney Failure, Acute/*etiology/therapy MH - Male MH - Rhabdomyolysis/*etiology MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 961114 DP - 1996 Sep 7 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 1820-2 CY - NETHERLANDS IP - 36 VI - 140 JC - NUK AA - Author EM - 9701 AB - In two men, aged 20 and 23 years, who suffered from fever, jaundice, severe muscle pain and decreased renal function, Weil's syndrome was diagnosed, accompanied by severe rhabdomyolysis. Haemodialysis was needed temporarily in one patient. Leptospirosis is a zoonosis caused by spirochaetes. It is a rare disorder in the Netherlands. In 5-10% of the patients so-called icteric leptospirosis is seen: Weil's syndrome. The diagnosis of Weil's syndrome is supported by the presence of high fever, intense muscle aching and jaundice. Renal involvement is frequent and haemodialysis is sometimes required. The pathogenesis of the tubular necrosis is unclear. Adequate therapy can prevent irreversible renal damage. AD - Sint Elisabethziekenhuis, Afd. Interne Geneeskunde, Tilburg. PMID- 8927145 TT - Rabdomyolyse en nierinsufficientie bij het syndroom van Weil. EA - A SO - Ned Tijdschr Geneeskd 1996 Sep 7;140(36):1820-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97105284 AU - Lawrence IG AU - Dalby RJ AU - Lad NR AU - Shepherd RJ TI - An atypical case of atypical pneumonia. LA - Eng MH - Adult MH - Case Report MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*complications/*diagnosis MH - Male MH - Pneumonia/*etiology PT - JOURNAL ARTICLE DA - 970107 DP - 1996 Sep IS - 0007-0947 TA - Br J Clin Pract PG - 346-8 CY - ENGLAND IP - 6 VI - 50 JC - AVK AA - Author EM - 9703 AB - A 23-year-old man, previously fit and well, presented with an atypical pneumonia, associated with microangiopathic anaemia, thrombocytopenia, rhabdomyolysis and renal impairment. Despite administration of intravenous fluids and antibiotics, his condition rapidly deteriorated, and the possibility of an aggressive connective tissue disorder was raised. Thus he was treated with high-dose oral steroids and plasma exchange until autoantibodies were shown to be negative. At this stage it transpired that the patient had swallowed water from a stream three weeks earlier, and leptospira antibody titres were subsequently found to be elevated. Antibiotics were continued, and after a protracted course he made a full recovery. Leptospirosis should be remembered as a rare cause of atypical pneumonia, particularly if there is associated hepatic or renal impairment. AD - Department of Medicine, Leicester General Hospital. PMID- 8983327 SO - Br J Clin Pract 1996 Sep;50(6):346-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 97128425 AU - Natrajaseenivasan K AU - Ratnam S TI - An investigation of leptospirosis in a laboratory animal house. LA - Eng MH - Animal MH - *Animals, Laboratory MH - Case-Control Studies MH - Guinea Pigs MH - Human MH - *Laboratory Personnel MH - Leptospirosis/*microbiology/*veterinary MH - Mice MH - Occupational Diseases/*microbiology MH - Prevalence MH - Rabbits MH - Rats MH - Rats, Wistar MH - Support, Non-U.S. Gov't MH - Zoonoses/*microbiology PT - JOURNAL ARTICLE DA - 970116 DP - 1996 Sep IS - 0019-5138 TA - J Commun Dis PG - 153-7 CY - INDIA IP - 3 VI - 28 JC - IBN AA - Author EM - 9703 AB - A study was undertaken to investigate the possible involvement of leptospires in causing infection and persistent deaths among albino mice and wistar rats of a laboratory animal house. The serological study revealed that 79.2% of mice, 90% of wistar rats, 71.4% of guinea pigs and 81.8% of rabbits had leptospiral antibodies to one or more of serogroups. Autumnalis predominated in guinea pigs and mice, while Javanica predominated in wistar rats. Rabbits exhibited equal seroprevalence of Autumnalis and Javanica. The animal house workers had 91.0% sero positivity, predominantly Autumnalis while control human group had only 20%. All isolations made from a mice (M2) and six wistar rats (W1, W4, W8 W9, W12 & W13) were serovar javanica and incidentally the isolate from a trapped house rat (R1) also belonged to the same serovar javanica. The house rat was perhaps the source of virulent leptospires for causing infection and mortality among laboratory animals like mice and wistar rats. AD - TN Dr. M.G.R. Medical University, Madras, Tamilnadu. PMID- 8973012 SO - J Commun Dis 1996 Sep;28(3):153-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 97053879 AU - Kikuchi N AU - Hiramune T AU - Takahashi T AU - Yanagawa R TI - Detection of leptospiral plasmid and comparison of plasmid profiles between virulent and avirulent leptospires. LA - Eng MH - Animal MH - Chemotaxis/physiology MH - Comparative Study MH - DNA, Bacterial/*analysis MH - Electrophoresis/methods/veterinary MH - Guinea Pigs MH - Hamsters MH - Hemoglobins/metabolism MH - Leptospira/*genetics/physiology/*pathogenicity MH - Plasmids/*analysis RN - 0 (DNA, Bacterial) RN - 0 (Hemoglobins) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 970206 DP - 1996 Sep IS - 0916-7250 TA - J Vet Med Sci PG - 915-7 SB - M CY - JAPAN IP - 9 VI - 58 JC - A27 AA - Author EM - 9704 AB - Detection of plasmid from leptospires and a comparison of the plasmid profiles between virulent and avirulent strains were performed to investigate whether leptospires contained plasmid(s) associated with virulence. Virulent strains of Leptospira interrogans serovars copenhageni, lai, canicola and pomona, which were virulent for the guinea pig and/or hamster and which showed chemotaxis toward hemoglobin, contained approximately 370 kilobases (kb) plasmid. Avirulent strains of L. interrogans also contained identical plasmid. Similar plasmid profiles in virulent and avirulent strains of L. interrogans were observed. These data showed that no plasmids associated with virulence or chemotaxis were detected. Strains of saprophytic leptospires, L. biflexa and Leptonema illini, did not possess any plasmid. AD - Department of epizootiology, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan. PMID- 8898293 SO - J Vet Med Sci 1996 Sep;58(9):915-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 97040296 AU - de Silva JJ TI - Experimental leptospirosis (L interrogans serovar copenhageni) of the guinea pig.studies on the pathogenesis and immunohistochemistry of hepatic lesions. LA - Eng LA - Por MH - Animal MH - Dissertations, Academic MH - Guinea Pigs MH - *Leptospira interrogans MH - Leptospirosis/*etiology/pathology MH - Liver Diseases/*etiology/pathology PT - JOURNAL ARTICLE DA - 961216 DP - 1996 Sep-Oct IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 511-2 CY - BRAZIL IP - 5 VI - 29 JC - RET EM - 9702 PMID- 8885678 SO - Rev Soc Bras Med Trop 1996 Sep-Oct;29(5):511-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 97040290 AU - Leite LT AU - Resende M AU - de Souza W AU - Camargos ER AU - Koury MC TI - Production and characterization of monoclonal antibodies to the EDTA extract of Leptospira interrogans, serovar icterohaemorrhagiae. LA - Eng MH - Animal MH - Antibodies, Monoclonal/*immunology MH - Bacterial Outer Membrane Proteins/*immunology/isolation & purification MH - Edetic Acid MH - Female MH - Hamsters MH - Human MH - IgG/immunology MH - IgM/immunology MH - Immunization, Passive MH - Leptospira interrogans/*immunology MH - Lipopolysaccharides/*immunology/isolation & purification MH - Mesocricetus MH - Mice MH - Mice, Inbred BALB C MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (IgG) RN - 0 (IgM) RN - 0 (Lipopolysaccharides) RN - 60-00-4 (Edetic Acid) PT - JOURNAL ARTICLE DA - 961216 DP - 1996 Sep-Oct IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 483-9 CY - BRAZIL IP - 5 VI - 29 JC - RET AA - Author EM - 9702 AB - Monoclonal antibodies (MABs) were produced against an ethylenediaminetetraacetate (EDTA) extract of Leptospira interrogans serovar icterohaemorrhagiae being characterized by gel precipitation as IgM and IgG (IgG1 and IgG2b). The EDTA extract was detected as several bands by silver staining in SDS-PAGE. In the Western blot the bands around 20 KDa reacted with a monoclonal antibody, 47B4D6, and was oxidized by periodate and was not digested by pronase, suggesting that the determinant is of carbohydrate nature. Immunocytochemistry, using colloidal gold labeling, showed that an EDTA extract determinant recognized by monoclonal antibody 47B4D6, is localized under the outer envelope of serovar icterohaemorrhagiae. The MAB raised against the EDTA extract was not able to protect hamsters from lethal challenge with virulent homologous leptospires. AD - Departmento de Microbiologia e Morfologia do Instituto de Ciencias Biolgicas, Universidade Federal de Minas Gerais, Belo Horizonte. PMID- 8885673 SO - Rev Soc Bras Med Trop 1996 Sep-Oct;29(5):483-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 97039132 AU - Duval D AU - Giger U TI - Vaccine-associated immune-mediated hemolytic anemia in the dog. LA - Eng MH - Anemia, Hemolytic/immunology/mortality/*veterinary MH - Animal MH - *Dog Diseases MH - Dogs MH - Erythrocyte Count MH - Hematocrit MH - Leukocyte Count MH - Medical Records MH - Retrospective Studies MH - Seasons MH - Support, U.S. Gov't, P.H.S. MH - Survival Rate MH - Vaccination/adverse effects/mortality/*veterinary PT - JOURNAL ARTICLE ID - HL02355/HL/NHLBI DA - 970123 DP - 1996 Sep-Oct IS - 0891-6640 TA - J Vet Intern Med PG - 290-5 SB - M CY - UNITED STATES IP - 5 VI - 10 JC - JVG AA - Author EM - 9703 AB - Vaccination has been incriminated as a trigger of immune-mediated hemolytic anemia (IMHA) in dogs and in people, but evidence to support this association is lacking. In a controlled retrospective study, idiopathic IMHA was identified in 58 dogs over a 27-month period. When compared with a randomly selected control group of 70 dogs (presented for reasons other than IMHA) over the same period, the distribution of cases versus time since vaccination was different (P < .05). Fifteen of the dogs (26%) had been vaccinated within 1 month (mean, 13 days; median, 14 days; range, 1 to 27 days) of developing IMHA (P < .0001), whereas in the control group no marked increase in frequency of presentation was seen in the first month after vaccination. The dogs with IMHA were divided into 2 groups based on time since vaccination: the vaccine IMHA group included dogs vaccinated within 1 month of developing IMHA; the nonvaccine IMHA group included dogs that developed IMHA more than 1 month after vaccination. The recently vaccinated dogs with IMHA (vaccine IMHA group) had significantly lower platelet counts (P < .05) and a trend towards increased prevalence of intravascular hemolysis and autoagglutination when compared with the nonvaccine IMHA group. Similar mortality rates were seen in teh vaccine IMHA group (60%) and the nonvaccine IMHA group (44%), with the majority of fatalities (> 75%) occurring in the first 3 weeks after presentation. Persistent autoagglutination was a negative prognostic indicator for survival in both groups (P < .05). Presence of icterus and hyperbilirubinemia were negative prognostic indicators for survival in the nonvaccine IMHA group (P < .0001 and P < .01, respectively) but not in the vaccine IMHA group. In the recently vaccinated dogs, combination vaccines from various manufacturers against canine distemper, adenovirus type 2, leptospirosis, parainfluenza, and parvovirus (DHLPP) were involved in each case. Vaccines against rabies virus, Bordetella spp, coronavirus, and Lyme Borrelia were administrated concomitantly to some dogs. This study provides the first clinical evidence for a temporal relationship of vaccine-associated IMHA in the dog. AD - Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA. PMID- 8884713 SO - J Vet Intern Med 1996 Sep-Oct;10(5):290-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [186 medline neighbors] UI - 96327145 AU - Woo TH AU - Smythe LD AU - Symonds ML AU - Norris MA AU - Dohnt MF AU - Patel BK TI - Rapid distinction between Leptonema and Leptospira by PCR amplification of 16S-23S ribosomal DNA spacer. LA - Eng MH - Base Sequence MH - Comparative Study MH - DNA Primers/genetics MH - DNA, Bacterial/*genetics MH - DNA, Ribosomal/*genetics MH - Leptospira/*genetics MH - Leptospiraceae/*genetics MH - Linkage (Genetics) MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - RNA, Bacterial/genetics MH - RNA, Ribosomal, 16S/*genetics MH - RNA, Ribosomal, 23S/*genetics MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal, 16S) RN - 0 (RNA, Ribosomal, 23S) PT - JOURNAL ARTICLE DA - 961021 DP - 1996 Aug 15 IS - 0378-1097 TA - FEMS Microbiol Lett PG - 85-90 SB - M CY - NETHERLANDS IP - 1 VI - 142 JC - FML AA - Author EM - 9612 AB - The PCR amplification of the genomic DNA of Leptonema illini strain 3055 using primers directed against conserved regions of the rRNA operon provided evidence that the 16S and 23S rRNA genes were linked via an intergenic spacer region. The sequencing of the intergenic spacer region indicated that it was 435 nucleotides in length and sequence similarity searches revealed that it bore no homology to any known sequences including tRNA available in databases. Further investigations using Southern blot hybridization revealed that there were two copies of these linked genes in the genome. However, similar PCR studies on a representative strain from each of the 23 serogroups of Leptospira interrogans, which are pathogenic, and eight strains from the 6 serogroups of Leptospira biflexa, which are non-pathogenic, revealed that the 16S and 23S rRNA genes were not linked. AD - School of Biomolecular and Biomedical Sciences, Faculty of Science and Technology, Griffith University, Nathan, Australia. PMID- 8759793 SI - GENBANK/U29662 SI - GENBANK/Z21632 SO - FEMS Microbiol Lett 1996 Aug 15;142(1):85-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 97009784 AU - Dhaliwal GS AU - Murray RD AU - Dobson H AU - Montgomery J AU - Ellis WA TI - Reduced conception rates in dairy cattle associated with serological evidence of Leptospira interrogans serovar hardjo infection. LA - Eng MH - Animal MH - Antibodies, Bacterial/isolation & purification MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - *Fertilization MH - Leptospira interrogans/*isolation & purification MH - Pregnancy MH - Support, Non-U.S. Gov't MH - Weil's Disease/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 961226 DP - 1996 Aug 3 IS - 0042-4900 TA - Vet Rec PG - 110-4 SB - M CY - ENGLAND IP - 5 VI - 139 JC - XBS AA - Author EM - 9702 AB - Fertility data from 673 cows in five dairy herds with a moderate to high seroprevalence of microscopic agglutination titres (MAT) of > or = 1:10 against Leptospira interrogans serovar hardjo were collated to assess the relationship between pregnancy rates and antibody titres to serovar hardjo. A significant proportion of failures of conception (10 to 13 per cent, P < 0.001) were associated with MATs of 1:10 to 1:100; the overall pregnancy rate of the seronegative cows was 28.5 per cent higher (P < 0.001) than that of the cows with MATs of > or = 1:100. First service pregnancy rates showed a similar trend but the differences were significant (P < 0.05) only in cows with antibody titres > or = 1:30. An assessment of other possible risk factors for reduced pregnancy rates, such as lactation number and calving to first service interval, had no effect on the statistical results of the study or its conclusions. AD - Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Neston, South Wirral. PMID- 8856888 SO - Vet Rec 1996 Aug 3;139(5):110-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 97097648 AU - Bolin CA TI - Diagnosis of leptospirosis: a reemerging disease of companion animals. LA - Eng MH - Animal MH - Animals, Domestic MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Leptospirosis/diagnosis/*veterinary MH - Serodiagnosis/*veterinary PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 961224 DP - 1996 Aug IS - 0882-0511 TA - Semin Vet Med Surg (Small Anim) PG - 166-71 CY - UNITED STATES IP - 3 VI - 11 JC - SEN AA - Author EM - 9702 AB - Canine leptospirosis has been known since 1899. Widespread use of canine leptospiral vaccines decreased the incidence of infection dramatically and reduced clinical attention to the disease. However, leptospirosis recently has reemerged as an important cause of febrile illness, and hepatic and renal disease in dogs. Feline leptospirosis is rare although the incidence of infection is higher than is recognized. Diagnosis of leptospirosis is difficult and no single diagnostic test provides optimal sensitivity or specificity. A combination of procedures, including serological assays and tests to detect the presence of leptospires in tissues or body fluids, is recommended. AD - Zoonotic Diseases Research Unit, United States Department of Agriculture, Ames, IA, USA. RF - 33 PMID- 8942213 SO - Semin Vet Med Surg (Small Anim) 1996 Aug;11(3):166-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 97049296 AU - Corney BG AU - Colley J TI - Restriction fragment length polymorphisms in Australian and New Zealand isolates of Leptospira interrogans serovar pomona. LA - Eng MH - Animal MH - Antibodies, Bacterial/immunology MH - Australia/epidemiology MH - DNA, Bacterial/*genetics MH - Genotype MH - Leptospira interrogans/*genetics/immunology MH - New Zealand/epidemiology MH - *Polymorphism, Restriction Fragment Length MH - Swine MH - Swine Diseases/epidemiology/immunology/prevention & control MH - Vaccines/immunology MH - Weil's Disease/epidemiology/prevention & control/veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (DNA, Bacterial) RN - 0 (Vaccines) PT - JOURNAL ARTICLE DA - 970113 DP - 1996 Aug IS - 0005-0423 TA - Aust Vet J PG - 156-7 SB - M CY - AUSTRALIA IP - 2 VI - 74 JC - 9IE EM - 9703 AD - Rockhampton Veterinary Laboratory, Department of Primary Industries, Queensland. PMID- 8894026 SO - Aust Vet J 1996 Aug;74(2):156-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97023875 AU - Redstone JS AU - Woodward MJ TI - The development of a ligase mediated PCR with potential for the differentiation of serovars within Leptospira interrogans. LA - Eng MH - Animal MH - Base Sequence MH - Deoxyribonucleases, Type II Site-Specific MH - DNA Primers MH - Leptospira interrogans/*classification/isolation & purification MH - Polydeoxyribonucleotide Synthetases MH - Polymerase Chain Reaction/*methods MH - Support, Non-U.S. Gov't RN - EC 3.1.21.- (endodeoxyribonuclease BglII) RN - EC 3.1.21.4 (Deoxyribonucleases, Type II Site-Specific) RN - EC 6.5.1.- (Polydeoxyribonucleotide Synthetases) RN - 0 (DNA Primers) PT - JOURNAL ARTICLE DA - 970218 DP - 1996 Aug IS - 0378-1135 TA - Vet Microbiol PG - 351-62 SB - M CY - NETHERLANDS IP - 3-4 VI - 51 JC - XBW AA - Author EM - 9704 AB - A ligase mediated polymerase chain reaction (LMPCR) was developed to amplify between the repetitive element, IS1533, of Leptospira and adjacent chromosomally located Bg/II restriction endonuclease enzyme sites. To do this, complimentary oligonucleotide linkers designed to anneal together with an overhanging Bg/II end were ligated to Bg/II digested DNA from 35 leptospiral reference strains and field isolates. This ligated DNA was used as template for PCR with oligonucleotide primers specific for the linker and for the repetitive element IS1533. The resultant amplicon profile hybridised a 102 bp region derived from the terminus of IS1533 thus confirming that amplicons generated by LMPCR contained part of IS1533. The number of fragments generated containing IS1533 was significantly fewer than that generated by RFLP but the LMPCR method has the potential to use far less template DNA and be quicker than standard RFLP. Obvious and reproducible interserovar differences were demonstrated by LMPCR whereas for 20 of 21 L. hardjo- bovis isolates tested no intraserovar differences were observed. Of those serovars known to possess IS1533 homologues and tested here by LMPCR, each produced a unique amplicon profile which hybridised the IS1533 terminus probe. The limited heterogeneity amongst hardjo-bovis isolates is discussed as is the potential contribution of this method to diagnosis, differentiation and the phylogenetics of the Leptospires. AD - Bacteriology Department, Central Veterinary Laboratory, New Haw, Addlestone, Surrey, UK. PMID- 8870196 SO - Vet Microbiol 1996 Aug;51(3-4):351-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 96374165 AU - Merien F AU - Perolat P TI - Public health importance of human leptospirosis in the South Pacific: a five-year study in New Caledonia. LA - Eng MH - Adult MH - Age Distribution MH - Agglutination Tests MH - Antibodies, Bacterial/blood MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology MH - Male MH - New Caledonia/epidemiology MH - Occupations MH - Prevalence MH - Retrospective Studies MH - Seasons MH - Sex Distribution RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 961001 DP - 1996 Aug IS - 0002-9637 TA - Am J Trop Med Hyg PG - 174-8 SB - A SB - M CY - UNITED STATES IP - 2 VI - 55 JC - 3ZQ AA - Author EM - 9612 AB - A retrospective study of 192 cases of human leptospirosis in New Caledonia (South Pacific) diagnosed between 1989 and 1993 showed that the disease was endemic throughout the territory. The annual incidence rate was 30 per 100,000 population, and the disease was more frequent in males (67.5%). Cases occurred mainly in March each year. Forty isolates were obtained (20.8%) and identified as belonging to serovars icterohaemorrhagiae (28), pomona (6), pyrogenes (3), ballum (2), and javanica (1). Most cases (54.7%) presented as influenza-like illnesses, while classical Weil's syndrome (fever, jaundice, and renal involvement) occurred in only 15.6% of the patients. Severe ocular complications were found in 3.6% of the patients. Local differences in climate, environment and socioeconomic conditions determined the epidemiologic features. These data emphasize the potential public health importance of leptospirosis in the other insular states in the South Pacific. AD - Leptospira Laboratory, Institute Pasteur, Noumea, New Caledonia. PMID- 8780456 SO - Am J Trop Med Hyg 1996 Aug;55(2):174-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [41 medline neighbors] UI - 96378955 AU - Levett PN AU - Whittington CU AU - Camus E TI - Serological survey of leptospirosis in livestock animals in the Lesser Antilles. LA - Eng MH - Animal MH - Caribbean Region/epidemiology MH - Cattle MH - *Cattle Diseases MH - Geography MH - *Goat Diseases MH - Goats MH - Leptospirosis/epidemiology/*veterinary MH - Prevalence MH - Serodiagnosis MH - Sheep MH - *Sheep Diseases MH - Support, Non-U.S. Gov't MH - West Indies/epidemiology PT - JOURNAL ARTICLE DA - 961018 DP - 1996 Jul 23 IS - 0077-8923 TA - Ann N Y Acad Sci PG - 369-77 SB - M SB - X CY - UNITED STATES VI - 791 JC - 5NM AA - Author EM - 9612 AB - A serological survey was performed of 1788 cattle, goats and sheep on 13 islands in the Lesser Antilles. Sera were tested by microscopic agglutination (MAT) using a panel of 22 live antigens. Evidence of past exposure, at a titer of > or = 100, was found in 101 animals (5.6%). Antibodies were more common in cattle and goats (7.2% in each) than in sheep (1.7%). Seroprevalence was highest in cattle in Martinique (20%) and in goats in St. Vincent (23%). The predominant serogroups were Sejroe (largely confined to cattle in Martinique), Autumnalis, Icterohaemorrhagiae, Grippotyphosa, and Cynopteri. Eleven cattle from Martinique and 2 sheep with titers of > or = 800 showed evidence of recent infection. AD - University of the West Indies, Faculty of Medical Sciences, Barbados. PMID- 8784518 SO - Ann N Y Acad Sci 1996 Jul 23;791:369-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 96416388 AU - Smyth JA AU - Goodall EA AU - McCoy MA AU - Ellis WA TI - Stillbirth/perinatal weak calf syndrome: a study of calves with an abnormal thyroid gland. LA - Eng MH - Animal MH - Body Weight MH - Cattle MH - Cattle Diseases/*pathology MH - Comparative Study MH - Female MH - Fetal Death/*veterinary MH - Organ Weight MH - Parity MH - Pregnancy MH - Syndrome MH - Thyroid Gland/*abnormalities/pathology MH - Thyroxine/blood RN - 7488-70-2 (Thyroxine) PT - JOURNAL ARTICLE DA - 961213 DP - 1996 Jul 6 IS - 0042-4900 TA - Vet Rec PG - 11-6 SB - M CY - ENGLAND IP - 1 VI - 139 JC - XBS AA - Author EM - 9702 AB - Data collected from 365 calves dead from stillbirth/perinatal weak calf syndrome were analysed to determine the predictive value of thyroid gland weight as an indicator of abnormality of the thyroid gland, and to examine the relationships between abnormality of the thyroid gland and other findings in the calves and also the parity of the dam. There was a significant relationship (P < 0.001) between the thyroid gland weight and bodyweight for the calves with a histologically normal thyroid gland, but there was no such relationship for calves with an abnormal thyroid gland. Only 1.1 per cent of the histologically normal thyroid glands weighed more than 30 g, indicating that there is a very high probability that glands weighing more than 30 g are abnormal. However, 76.0 per cent of moderately to severely affected glands weighed less than 30 g. The following significant differences between calves with an abnormal and those with a normal thyroid gland were established. Abnormal thyroid glands were significantly heavier (P < 0.01), constituted a significantly greater percentage of the calf's bodyweight (P < 0.01) and had a significantly lower iodine concentration (P < 0.001). A significantly higher proportion of calves with an abnormal thyroid gland had uninflated lungs (P < 0.01), and a significantly higher proportion had pneumonia (P < 0.01). Abnormal thyroid glands were associated with a low selenium concentration in the kidneys. There were no associations between abnormalities of the thyroid gland and the parity of the dam, the presence of skeletal fractures, the weight or sex of the calf, infection with leptospira, Salmonella dublin, Bacillus species, Actinomyces pyogenes or Aspergillus species, the quantities of hepatic iron pigment, liver vitamin E concentration or serum cholesterol concentration. AD - Veterinary Sciences Division, Department of Agriculture for Northern Ireland, Stormont, Belfast. PMID- 8819288 SO - Vet Rec 1996 Jul 6;139(1):11-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 97062001 AU - Shubich MG AU - Evglevskii AA AU - Lebedev VV AU - Avdeeva MG TI - [Study of acid lability of DNA in patients with leptospirosis] LA - Rus MH - Acids MH - Adult MH - Aged MH - Cell Nucleus/ultrastructure MH - Chromatin/genetics MH - Comparative Study MH - DNA/*analysis MH - English Abstract MH - Female MH - Fluorescence MH - Human MH - Hydrolysis MH - Male MH - Middle Age MH - Neutrophils/cytology MH - Weil's Disease/*diagnosis/*genetics RN - 0 (Acids) RN - 0 (Chromatin) RN - 9007-49-2 (DNA) PT - JOURNAL ARTICLE DA - 961213 DP - 1996 Jul-Aug IS - 0869-2084 TA - Klin Lab Diagn PG - 25-6 CY - RUSSIA IP - 4 JC - B17 AA - Author EM - 9702 AB - Measurements of DNA and study of chromatin status in blood cell nuclei help solve numerous basic problems of biology and medicine. Acid lability of DNA was assessed in 5 patients with grave icterohemorrhagic leptospirosis. The distribution of fluorescence peaks on the curve of neutrophil DNA hydrolysis in patients with grave leptospirosis indicates that functionally low-active acid-resistant DNA fraction predominates in their chromatin. Assessment of acid lability of DNA is proposed to be used for assessing the severity of the pathological process. PMID- 8963553 TT - Izuchenie kislotolabil'nosti DNK u bol'nykh leptospirozom. EA - A SO - Klin Lab Diagn 1996 Jul-Aug;(4):25-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 96438679 AU - Farina R AU - Cerri D AU - Renzoni G AU - Andreani E AU - Mani P AU - Ebani V AU - Pedrini A AU - Nuvoloni R TI - Leptospira interrogans in the genital tract of sheep. Research on ewes and rams experimentally infected with serovar hardjo (hardjobovis). LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Colony Count, Microbial MH - Female MH - Genitalia/*microbiology MH - Kidney/microbiology MH - Leptospira interrogans/immunology/isolation & purification/*pathogenicity MH - Leptospirosis/blood/microbiology/*veterinary MH - Male MH - Sheep MH - Sheep Diseases/blood/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 961210 DP - 1996 Jul IS - 1121-7138 TA - New Microbiol PG - 235-42 SB - M CY - ITALY IP - 3 VI - 19 JC - CGC AA - Author EM - 9702 AB - To verify if Leptospira hardjo can colonize the male and female genital organs of sheep, 9 animals (6 non pregnant ewes and 3 mature rams) were infected with a strain of L. hardjobovis recently recovered from the kidneys of a seropositive ewe. Postinfection controls (bacteriologic, serologic, immunohistochemistry and electron microscopy) failed to disclose the presence of leptospires in the uterus and oviducts, testicles, epididymis, prostate and bulbourethral glands of animals used for the experiment and slaughtered from 37 to 242 postinfection days. All animals showed a renal localization of L. hardjobovis lasting for the entire period of the study (over 8 months). These results emphasize the important role of sheep as maintenance hosts of the serovar. AD - Department of Animal Pathology, Prophylaxis and Food Hygiene, Faculty of Veterinary Medicine, University of Pisa, Italy. PMID- 8841039 SO - New Microbiol 1996 Jul;19(3):235-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 96415690 AU - Hogan PM AU - Bernard WV AU - Kazakevicius PA AU - Fitzgerald MR TI - Acute renal disease due to Leptospira interrogans in a weanling. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis/blood MH - Case Report MH - Diagnosis, Differential MH - Female MH - Horse Diseases/*etiology MH - Horses MH - Kidney Failure, Acute/etiology/*veterinary MH - *Leptospira interrogans/immunology MH - Leptospirosis/complications/diagnosis/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 961205 DP - 1996 Jul IS - 0425-1644 TA - Equine Vet J PG - 331-3 SB - M CY - ENGLAND IP - 4 VI - 28 JC - EJ9 EM - 9702 AD - Rood and Riddle Equine Hospital, Lexington, Kentucky 40580-2070, USA. PMID- 8818600 SO - Equine Vet J 1996 Jul;28(4):331-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 96415689 AU - Kinde H AU - Hietala SK AU - Bolin CA AU - Dowe JT TI - Leptospiral abortion in horses following a flooding incident. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Antibodies, Bacterial/blood MH - Female MH - Fetus/microbiology MH - Horse Diseases/*etiology/microbiology/pathology MH - Horses MH - Kidney/embryology/microbiology/pathology MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/complications/*veterinary MH - Liver/embryology/microbiology/pathology MH - *Natural Disasters MH - Pregnancy RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 961205 DP - 1996 Jul IS - 0425-1644 TA - Equine Vet J PG - 327-30 SB - M CY - ENGLAND IP - 4 VI - 28 JC - EJ9 EM - 9702 AD - California Veterinary Diagnostic Laboratory System, University of California, Davis 95616, USA. PMID- 8818599 SO - Equine Vet J 1996 Jul;28(4):327-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 96376816 AU - Feresu SB AU - Korver H AU - Riquelme N AU - Baranton G AU - Bolin CA TI - Two new leptospiral serovars in the Hebdomadis serogroup isolated from Zimbabwe cattle. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - DNA, Bacterial/analysis MH - Electrophoresis, Gel, Pulsed-Field MH - Leptospira/*classification/genetics/immunology/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Polymorphism, Restriction Fragment Length MH - Serotyping MH - Support, U.S. Gov't, P.H.S. MH - Zimbabwe RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE ID - IF05TW4154-01/TW/FIC DA - 961021 DP - 1996 Jul IS - 0020-7713 TA - Int J Syst Bacteriol PG - 694-8 SB - M CY - UNITED STATES IP - 3 VI - 46 JC - AWO AA - Author EM - 9612 AB - Four strains belonging to the genus Leptospira serogroup Hebdomadis were isolated from Zimbabwe cattle at slaughter. These isolates were subjected to cross-agglutinin absorption tests and to restriction fragment length polymorphism and pulsed-field gel electrophoresis analyses of their genomic DNAs. One of these strains represents a new serovar, for which the name mhou is proposed; strain SBF 40 is the reference strain of this serovar. The other three strains belong to a second new serovar, for which the name marondera is proposed; the reference strain of this serovar is strain SBF 5. The three strains of serovar marondera could be differentiated by their restriction fragment polymorphism and pulsed-field gel electrophoretic patterns. AD - Department of Biological Sciences, University of Zimbabwe, Mount Pleasant, Harare, Zimbabwe. feresu@zimbix.uz.zw PMID- 8782678 SO - Int J Syst Bacteriol 1996 Jul;46(3):694-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [70 medline neighbors] UI - 96331629 AU - Labalme MJ AU - Chaabane-Masmoudi S AU - Mathieu L AU - Perol M AU - Nesme P AU - Guerin JC TI - [Isolated febrile intra-alveolar hemorrhage detected in leptospirosis] LA - Fre MH - Adult MH - Bronchoalveolar Lavage Fluid/cytology MH - Case Report MH - English Abstract MH - Female MH - Fever MH - Hemoptysis/*etiology MH - Human MH - Pulmonary Alveoli/*pathology MH - Septicemia/microbiology MH - Weil's Disease/*complications/diagnosis PT - JOURNAL ARTICLE DA - 961001 DP - 1996 Jul IS - 0761-8425 TA - Rev Mal Respir PG - 310-2 SB - M CY - FRANCE IP - 3 VI - 13 JC - RZ9 AA - Author EM - 9612 AB - We report observation of a patient of 25 years who presented with an isolated intra-alveolar haemorrhage occurring during the course of an illness suggestive of septicaemia. Considering the epidemiological context of inhalation of water from the River Saone, the diagnosis of acute leptospirosis ictero-haemorrhagica was considered and was confirmed by serological tests. Several publications draw attention to the pulmonary manifestations of acute leptospirosis which remains rare and poorly understood. Pulmonary disease is characterised not by an infectious alveolitis but by the occurrence of intra-alveolar haemorrhage whose pathogenetic mechanism remains under discussion. AD - Hopital de la Croix-Rousse, Lyon. PMID- 8765927 TT - Hemorragie intra-alveolaire febrile isolee revelant une leptospirose. EA - A SO - Rev Mal Respir 1996 Jul;13(3):310-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96387715 AU - Lilenbaum W AU - Santos MR TI - Effect of management systems on the prevalence of bovine leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Brazil/epidemiology MH - Cattle MH - Cattle Diseases/blood/*epidemiology/*prevention & control MH - *Disease Management MH - Leptospira/immunology MH - Leptospirosis/epidemiology/prevention & control/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 961205 DP - 1996 Jun 8 IS - 0042-4900 TA - Vet Rec PG - 570-1 SB - M CY - ENGLAND IP - 23 VI - 138 JC - XBS EM - 9702 AD - Department of Microbiology and Parasitology, University Federal Fluminense, Brazil. PMID- 8795185 SO - Vet Rec 1996 Jun 8;138(23):570-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97223699 AU - Ribeiro MA AU - Brandao AP AU - Romero EC TI - Evaluation of diagnostic tests for human leptospirosis. LA - Eng MH - Agglutination Tests/methods MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay/methods MH - Human MH - IgM MH - Leptospirosis/*diagnosis MH - Sensitivity and Specificity MH - Serine Proteinases RN - EC 3.4.21 (Serine Proteinases) RN - 0 (IgM) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE DA - 970520 DP - 1996 Jun IS - 0100-879X TA - Braz J Med Biol Res PG - 773-7 SB - M CY - BRAZIL IP - 6 VI - 29 JC - BOF AA - Author EM - 9707 AB - The IgM-PK-ELISA, an enzyme-linked immunosorbent assay for immunoglobulin M employing a proteinase K-treated antigen, and the "Leptoteste-S" macroagglutination test were evaluated for use in a rapid serodiagnosis of human leptospirosis. The microscopic agglutination test (MAT) was used as reference. The three serological tests were applied to serum samples from patients with leptospirosis (N = 89), typhoid fever (N = 8), malaria (N = 19), syphilis (N = 20), hepatitis (N = 16) and from clinically healthy donors (N = 92). The overall results of the IgM-PK-ELISA and the "Leptoteste-S" are comparable to those of the MAT. However, both tests differed statistically from MAT in terms of the positivity of the acute-phase sera, with approximately 38% of the patients with leptospirosis being identified earlier than when MAT was used. The IgM-PK-ELISA, with 89.9% sensitivity and 97.4% specificity, could be the test of choice for those laboratories which are equipped to perform ELISA. The "Leptoteste- S", with 89.9% sensitivity and 94.8% specificity, seems to be easier to perform and the most accessible to peripheral laboratories for rapid screening of human sera. Both techniques present the important characteristic of detecting early antibodies against leptospires, thus providing a diagnosis during the early stages of the disease. AD - Secao de Imunologia, Instituto Adolfo Lutz, Sao Paulo, SP, Brasil. PMID- 9070390 SO - Braz J Med Biol Res 1996 Jun;29(6):773-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 97038612 AU - Dastis-Bendala C AU - de Villar-Conde E AU - Marin-Leon I AU - Manzanares-Torne L AU - Perez-Lozano MJ AU - Cano-Fuentes G AU - Vargas-Romero J AU - Pumarola-Sune T TI - Prospective serological study of leptospirosis in southern Spain. LA - Eng MH - Adolescence MH - Adult MH - Cohort Studies MH - Female MH - Follow-Up Studies MH - Fresh Water/microbiology MH - Human MH - Incidence MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*epidemiology/transmission MH - Male MH - Middle Age MH - Occupational Diseases/blood/*epidemiology MH - *Occupational Exposure MH - Prevalence MH - Prospective Studies MH - Seroepidemiologic Methods MH - Spain/epidemiology MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 970220 DP - 1996 Jun IS - 0392-2990 TA - Eur J Epidemiol PG - 257-62 SB - M CY - NETHERLANDS IP - 3 VI - 12 JC - ERE AA - Author EM - 9704 AB - This article reports data concerning a serosurvey carried out in Southern Spain to assess the current epidemiological status of a population exposed to risk of leptospirosis. Microagglutination and IgM- EIA tests were carried out on sera from a sample of workers in agriculture-related occupations, exposed to marsh waters. A cohort of 197 workers were followed for a year in an active surveillance program to evaluate seroconversion (laboratory confirmed leptospirosis). The results have shown for the cohort a density of incidence: 6.4 x 100 persons per year, and for the reference population an accumulated incidence of 41.25/100,000. Prevalence rates (P) were 21.3 x 100 and 144 x 10(5) for the cohort and population respectively. Rates were higher in cray-fishers (P: 62.7%), rice-workers, and butchers. This is the first report identifying cray-fishers as a high risk group for leptospirosis, and the reporting of human contamination by Australis serogroup in Spain. AD - Family Medicine, Valme University Hospital, Seville, Spain. PMID- 8884193 SO - Eur J Epidemiol 1996 Jun;12(3):257-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 96228170 AU - Paganin F AU - Gauzere BA AU - Lugagne N AU - Blanc Ph AU - Roblin X TI - Bronchoalveolar lavage in rapid diagnosis of leptospirosis [letter; comment] LA - Eng MH - Adult MH - Bronchoalveolar Lavage Fluid/*microbiology MH - Diagnosis, Differential MH - Hemorrhage/*diagnosis/microbiology MH - Human MH - Leptospirosis/*diagnosis/epidemiology MH - Lung Diseases/*diagnosis/microbiology MH - Male MH - Reunion/epidemiology MH - Time Factors PT - COMMENT PT - LETTER DA - 960819 DP - 1996 Jun 1 IS - 0140-6736 TA - Lancet PG - 1562-3 SB - A SB - M SB - X CY - ENGLAND IP - 9014 VI - 347 JC - L0S EM - 9610 CM - Comment on: Lancet 1996 Feb 24;347(9000):535-6 RO - M:LC2 PMID- 8684140 LR - 961006 SO - Lancet 1996 Jun 1;347(9014):1562-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 protein link] [1 nucleotide link] [121 medline neighbors] UI - 96239055 AU - Shang ES AU - Summers TA AU - Haake DA TI - Molecular cloning and sequence analysis of the gene encoding LipL41, a surface-exposed lipoprotein of pathogenic Leptospira species. LA - Eng MH - Amino Acid Sequence MH - Animal MH - Antibiotics, Peptide/pharmacology MH - Bacterial Proteins/*genetics MH - Base Sequence MH - Cloning, Molecular MH - Leptospira/*chemistry/genetics MH - Lipoproteins/*genetics MH - Male MH - Membrane Proteins/*genetics MH - Molecular Sequence Data MH - Oligonucleotide Probes MH - Rabbits MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Support, U.S. Gov't, P.H.S. RN - 0 (Antibiotics, Peptide) RN - 0 (Bacterial Proteins) RN - 0 (Lipoproteins) RN - 0 (Membrane Proteins) RN - 0 (Oligonucleotide Probes) RN - 67076-74-8 (globomycin) PT - JOURNAL ARTICLE ID - 2-T32-AI07323-06/AI/NIAID ID - CA16042/CA/NCI DA - 960812 DP - 1996 Jun IS - 0019-9567 TA - Infect Immun PG - 2322-30 SB - X SB - M CY - UNITED STATES IP - 6 VI - 64 JC - GO7 AA - Author EM - 9610 AB - We report the cloning of the gene encoding a surface-exposed leptospiral lipoprotein, designated LipL41. In a previous study, a 41- kDa protein antigen was identified on the surface of Leptospira kirschneri (D. A. Haake, E. M. Walker, D. R. Blanco, C. A. Bolin, J. N. Miller, and M. A. Lovett, Infect. Immun. 59:1131-1140, 1991). We obtained the N-terminal amino acid sequence of a staphylococcal V8 proteolytic-digest fragment in order to design an oligonucleotide probe.A Lambda ZAP II library containing EcoRI fragments of L. kirschneri DNA was screened, and a 2.3-kb DNA fragment which contained the entire structural lipL41 gene was identified. The deduced amino acid sequence of LipL41 would encode a 355-amino-acid polypeptide with a 19-amino-acid signal peptide, followed by an L-X-Y-C lipoprotein signal peptidase cleavage site. A recombinant His6-LipL41 fusion protein was expressed in Escherichia coli in order to generate specific rabbit antiserum. LipL41 is solubilized by Triton X-114 extraction of L. kirschneri; phase separation results in partitioning of LipL41 exclusively into the detergent phase. At least eight proteins, including LipL41 and the other major Triton X-114 detergent phase proteins, are intrinsically labeled during incubation of L. kirschneri in media containing [3H] palmitate. Processing of LipL41 is inhibited by globomycin, a selective inhibitor of lipoprotein signal peptidase. Triton X-100 extracts of L. kirschneri contain immunoprecipitable OmpL1 (porin), LipL41, and another lipoprotein, LipL36. However, in contrast to LipL36, only LipL41 and OmpL1 were exposed on the surface of intact organisms. Immunoblot analysis of a panel of Leptospira species reveals that LipL41 expression is highly conserved among leptospiral pathogens. AD - Department of Microbiology & Immunology, UCLA School of Medicine, Los Angeles, California 90095, USA. RO - M:CNR PMID- 8675344 LR - 960911 SI - GENBANK/L46794 SO - Infect Immun 1996 Jun;64(6):2322-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [89 medline neighbors] UI - 96225375 AU - Paganin F AU - Gauzere BA AU - Lugagne N AU - Blanc P AU - Roblin X TI - Bronchoalveolar lavage in rapid diagnosis of leptospirosis [letter; comment] LA - Eng MH - Adult MH - Bronchoalveolar Lavage Fluid/*microbiology MH - Hemorrhage/diagnosis/*microbiology MH - Human MH - Kidney Failure, Acute/diagnosis/*microbiology MH - Lung Diseases/diagnosis/*microbiology MH - Male MH - Reunion/epidemiology MH - Time Factors MH - Weil's Disease/*diagnosis/epidemiology PT - COMMENT PT - LETTER DA - 960815 DP - 1996 May 25 IS - 0140-6736 TA - Lancet PG - 1483-4 SB - A SB - M SB - X CY - ENGLAND IP - 9013 VI - 347 JC - L0S EM - 9610 CM - Comment on: Lancet 1996 Feb 24;347(9000):535-6 RO - M:LC2 PMID- 8676650 LR - 961006 SO - Lancet 1996 May 25;347(9013):1483-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [97 medline neighbors] UI - 96242320 AU - Cinco M AU - Vecile E AU - Murgia R AU - Dobrina P AU - Dobrina A TI - Leptospira interrogans and Leptospira peptidoglycans induce the release of tumor necrosis factor alpha from human monocytes. LA - Eng MH - Biological Assay MH - Dose-Response Relationship, Drug MH - Human MH - Immunoassay MH - In Vitro MH - Leptospira interrogans/*pathogenicity MH - Monocytes/*immunology MH - Peptidoglycan/administration & dosage/*toxicity MH - Tumor Necrosis Factor/analysis/*secretion MH - Weil's Disease/etiology/immunology RN - 0 (Peptidoglycan) RN - 0 (Tumor Necrosis Factor) PT - JOURNAL ARTICLE DA - 970219 DP - 1996 May 1 IS - 0378-1097 TA - FEMS Microbiol Lett PG - 211-4 SB - M CY - NETHERLANDS IP - 2-3 VI - 138 JC - FML AA - Author EM - 9704 AB - Elevated plasma concentrations of the cytokine tumor necrosis factor alpha (TNF alpha) have been observed in patients affected by leptospirosis. In this study we found that a preparation of peptidoglycan of Leptospira interrogans, serovar copenhageni, was able to induce the release of TNF alpha from peripheral blood mononuclear cells. TNF alpha induction occurred in a dose dependent manner and was not affected by the endotoxin inhibitor polymixin B. This is the first report on induction of TNF alpha release by a peptidoglycan of spirochetes. Our findings are consistent with existing clinical data and provide a potential mechanism for TNF alpha production. AD - Institute of Microbiology, University of Trieste, Italy. cinco@univ.trieste.it PMID- 9026448 SO - FEMS Microbiol Lett 1996 May 1;138(2-3):211-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 97149953 AU - Rosicky B AU - Minar J TI - The role of the National Institute of Public Health in the field of infections with natural focality. LA - Eng MH - *Academies and Institutes MH - Animal MH - Birds/VI MH - Chiroptera/VI MH - Czech Republic/epidemiology MH - Disease Reservoirs MH - Human MH - Infection/*epidemiology MH - Parasitic Diseases/epidemiology MH - *Public Health MH - Virus Diseases/epidemiology/transmission MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 970320 DP - 1996 May IS - 1210-7778 TA - Cent Eur J Public Health PG - 123-6 SB - M CY - CZECH REPUBLIC IP - 2 VI - 4 JC - BO6 AA - Author EM - 9705 AB - In the post-war period the National Institute of Public Health, later Institutes of Epidemiology and Microbiology, headed by K. Raska, ranked among famous laboratories in the world due to its priority findings and original results. Research results of the Institute stimulated further research not only in Czechoslovakia but also abroad, in laboratories of Europe and America. The authors emphasize the significance of certain results in the epidemiology and ecology of infections characterized by natural focality. In the first place they discuss the isolation of TBE in 1948 and 1949 by Gallia et al., and the study of the role of birds and bats as hosts of TBE. Significant for the recognition of zoonotic influenza viruses are papers by Tumova, and as regards rabies in rodents the studies of Sodja et al. The institute paid attention to the introduction of Coxiella burnetii into the north-west of Bohemia. The institute's activities in the study of tularaemia, leptospirosis, Lyme borreliosis, and toxoplasmosis are also described. Raska's concept of epidemiological surveillance in the prevention of zoonoses with natural focality was fully enforced by workers of the institute. Many results of the Institute have been adopted by the WHO; it was demonstrated that it is possible by appropriate methods not only to detect human diseases in places where they are known but also to discover them in nature extensively altered by man. AD - National Institute of Public Health, Prague, Czech Republic. PMID- 8996726 SO - Cent Eur J Public Health 1996 May;4(2):123-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [38 medline neighbors] UI - 96367608 AU - Anan'ina IuV TI - [The molecular genetic and biological aspects of the ecology of pathogenic Leptospira (Leptospira interrogans)] LA - Rus MH - Animal MH - DNA, Bacterial/genetics MH - Ecology MH - English Abstract MH - Genome, Bacterial MH - Leptospira interrogans/classification/*genetics/*pathogenicity MH - Polymerase Chain Reaction MH - Serotyping RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 961127 DP - 1996 May-Jun IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 19-21 SB - M CY - RUSSIA IP - 3 JC - Y9O AA - Author EM - 9701 AB - The results of recent investigations on the application of some genotyping methods (genomic fingerprinting, analysis of restriction length fragment polymorphism of DNA, etc.), made in order to study the population structure of pathogenic leptospires and to evaluate their intraspecies heterogeneity with regard to their main ecological features, are reviewed. New data on the use of PRC-based amplification test systems for the study of specific features of host persistence of leptospires are presented. The relative role of the parasitic and saprophytic phases of existence for populations of pathogenic leptospires belonging to different intraspecies taxa is discussed. RF - 27 PMID- 8771722 TT - Molekuliarno-geneticheskie i biologicheskie aspekty ekologii patogennykh leptospir (Leptospira interrogans). EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1996 May-Jun;(3):19-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] UI - 96292911 AU - Rodriguez-Villalobos H AU - Elcuaz R AU - Lafarga B AU - Mosguera M AU - Apolinario R AU - Jimenez P TI - [Leptospirosis in Gran Canaria: report of 2 cases (letter)] LA - Spa MH - Adolescence MH - Aged MH - Case Report MH - Human MH - *Leptospirosis/diagnosis MH - Male MH - Spain PT - LETTER DA - 961114 DP - 1996 May IS - 0213-005X TA - Enferm Infecc Microbiol Clin PG - 335-6 CY - SPAIN IP - 5 VI - 14 JC - A10 EM - 9701 PMID- 8744382 TT - Leptospirosis en Gran Canaria: a proposito de 2 casos. SO - Enferm Infecc Microbiol Clin 1996 May;14(5):335-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [9 medline neighbors] UI - 96312659 AU - Novinger MS AU - Sullivan PS AU - McDonald TP TI - Determination of the lifespan of erythrocytes from greyhounds, using an in vitro biotinylation technique. LA - Eng MH - Animal MH - Biotin/*metabolism MH - Breeding MH - Cell Survival/genetics/physiology MH - Dogs/*blood/genetics MH - Erythrocyte Aging/genetics/*physiology MH - Erythrocyte Membrane/physiology/ultrastructure MH - Erythrocytes/cytology/*metabolism/*physiology MH - Female MH - Flow Cytometry/methods/veterinary MH - Hemoglobins/analysis MH - In Vitro MH - Linear Models MH - Male MH - Platelet Count/veterinary MH - Time Factors RN - 0 (Hemoglobins) RN - 58-85-5 (Biotin) PT - JOURNAL ARTICLE DA - 961022 DP - 1996 May IS - 0002-9645 TA - Am J Vet Res PG - 739-42 SB - M CY - UNITED STATES IP - 5 VI - 57 JC - 40C AA - Author EM - 9612 AB - OBJECTIVE--To determine the RBC lifespan of Greyhounds, using an in vitro labeling technique. DESIGN--RBC from dogs were labeled with NHS- biotin and their disappearance measured over time to determine RBC lifespan. SAMPLE POPULATION--5 Greyhounds that had been vaccinated against distemper, adenovirus 1 and 2 infections, parainfluenza, leptospirosis, parvovirus, and coronavirus infections, Bordetella bronchiseptica infection, and rabies the previous year; 3 sexually intact 14-month-old Beagles served as controls. PROCEDURE--After venipuncture for CBC, catheters were inserted in the cephalic vein of each dog. Butorphanol was then administered to achieve mild sedation and analgesia, and glycopyrrolate was administered to ensure maintenance of adequate heart rate during phlebotomy. Dogs were positioned in lateral recumbency; blood was removed via jugular venipuncture, using a standard laboratory donor blood bag containing citrate-phosphate-dextrose solution. Blood was transferred aseptically into sterile polystyrene containers and NHS-biotin was added. After incubation, the labeled RBC were reinfused into the dogs and the blood was allowed to recirculate for 1 hour before the first postinfusion sample was taken. At frequent intervals, blood to be analyzed was taken by jugular venipuncture, and the percentage of labeled cells was determined by flow cytometry. RESULTS--The mean RBC lifespan of non- Greyhounds was significantly longer than that of Greyhounds (104.3 +/- 2.2 days vs 53.6 +/- 6.5 days; P = 0.001). A negative linear correlation was also found between age of the Greyhounds and their RBC lifespan (P = 0.01, R2 = 0.91). CONCLUSIONS--The shorter RBC lifespan of the Greyhounds may explain the finding of macrocytosis reported in earlier work. The reason for the shorter RBC lifespan in Greyhounds may be caused by differences in Greyhound RBC membrane structure or accelerated RBC removal from the circulation. AD - Department of Animal Science, College of Veterinary Medicine, University of Tennessee, Knoxville 37901-1071, USA. PMID- 8723892 SO - Am J Vet Res 1996 May;57(5):739-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 96290852 AU - Dhaliwal GS AU - Murray RD AU - Dobson H AU - Montgomery J AU - Ellis WA TI - Effect of vaccination against Leptospira interrogans serovar hardjo on milk production and fertility in dairy cattle. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - Comparative Study MH - Female MH - *Fertility MH - *Lactation MH - Leptospira interrogans/*classification MH - Support, Non-U.S. Gov't MH - *Vaccination MH - Weil's Disease/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 960925 DP - 1996 Apr 6 IS - 0042-4900 TA - Vet Rec PG - 334-5 SB - M CY - ENGLAND IP - 14 VI - 138 JC - XBS EM - 9611 AD - Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Neston, South Wirral. PMID- 8730678 SO - Vet Rec 1996 Apr 6;138(14):334-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 96390318 AU - Cherkasskii BL AU - Shumilov PK AU - Manenkova GM TI - [The epidemiologic-epizootiologic characteristics of leptospirosis in the Moscow region] LA - Rus MH - Adult MH - Age Distribution MH - Animal MH - Animals, Domestic MH - Animals, Wild MH - Child MH - Female MH - Human MH - Leptospirosis/*epidemiology/*veterinary MH - Male MH - Middle Age MH - Morbidity/trends MH - Moscow/epidemiology MH - Retrospective Studies MH - Russia/epidemiology MH - Sex Distribution MH - Urban Population/statistics & numerical data MH - Weil's Disease/*epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 961120 DP - 1996 Apr-Jun IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 32-6 CY - RUSSIA IP - 2 JC - M72 EM - 9701 PMID- 8926932 TT - Epidemiologo-epizootologicheskie osobennosti leptospiroza v Moskovskom regione. SO - Med Parazitol (Mosk) 1996 Apr-Jun;(2):32-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97014134 AU - Masuzawa T AU - Suzuki R AU - Yanagihara Y TI - Protective activity of rabbit polyclonal anti-idiotype antibody against Leptospira interrogans infection in hamsters. LA - Eng MH - Agglutination/immunology MH - Animal MH - Antibodies, Anti-Idiotypic/*immunology/metabolism MH - Antibodies, Monoclonal/immunology MH - Antigens, Bacterial/immunology/metabolism MH - Bacterial Vaccines/*immunology MH - Enzyme-Linked Immunosorbent Assay MH - Hamsters MH - Immunoglobulin Idiotypes/immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/*immunology/prevention & control MH - Male MH - Mesocricetus MH - Mice MH - Rabbits RN - 0 (Antibodies, Anti-Idiotypic) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (Immunoglobulin Idiotypes) PT - JOURNAL ARTICLE DA - 970430 DP - 1996 Apr IS - 0918-6158 TA - Biol Pharm Bull PG - 613-5 SB - M CY - JAPAN IP - 4 VI - 19 JC - BPZ AA - Author EM - 9707 AB - We prepared an anti-idiotype (Id) antibody against leptospirosis. Serum from rabbit immunized with monoclonal antibody (MAb) LW2, which reacted to the main protective antigen prepared from Leptospira interrogans serovar lai, inhibited agglutination of the organism by MAb LW2. The immune rabbit serum was applied to a column coupled with normal mouse IgG as a ligand (first column), and the unbound fraction eluted was applied to a column coupled with MAb LW2 as a ligand (second column). The bound fraction (anti-Id antibody) eluted from the second column inhibited the binding of MAb LW2 to sonicated leptospiral cells in ELISA. Mice produced antibodies against Leptospira by intraperitoneal immunization with the anti-Id antibody at doses of 2 mu g/mouse or more. Hamsters were protected by immunization with the anti-Id antibody at doses of 2 and 20 mu g/hamster from the lethal infection of Leptospira. This is the first report concerning the use of an anti-Id antibody against leptospirosis. AD - Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka, Japan. PMID- 8860969 SO - Biol Pharm Bull 1996 Apr;19(4):613-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 96363986 AU - Chambers MA AU - Swango LJ AU - Wright JC TI - Novel indirect fluorescent antibody test for Lyme disease. LA - Eng MH - Animal MH - Bacterial Adhesion MH - Bias (Epidemiology) MH - Borrelia burgdorferi/isolation & purification/physiology MH - Comparative Study MH - *Dog Diseases MH - Dogs MH - Endothelium, Vascular/microbiology/pathology MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique, Indirect/veterinary MH - Horse Diseases MH - Horses MH - Human MH - Lyme Disease/diagnosis/*veterinary MH - Neoplasms/veterinary MH - Reproducibility of Results MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE ID - 1 R15 AI 31180-01/AI/NIAID DA - 970325 DP - 1996 Apr IS - 1040-6387 TA - J Vet Diagn Invest PG - 196-201 SB - M CY - UNITED STATES IP - 2 VI - 8 JC - A2D AA - Author EM - 9705 AB - An indirect fluorescent antibody (IFA) test was developed using a novel format of Borrelia burgdorferi organisms adhered to a monolayer of cultured endothelial cells derived from an equine tumor. Sensitivity and specificity of the new IFA test for detecting anti-B, burgdorferi antibodies were evaluated using sera from dogs inoculated with live B. burgdorferi or vaccinated with B. burgdorferi bacterin or leptobacterins and from unvaccinated specific-pathogen-free (SPF) dogs. To compare the new IFA test with existing tests, serum samples were submitted to independent laboratories to be tested by enzyme-linked immunosorbent assay (ELISA) and a traditional IFA test. Samples were also tested with 2 commercially available membrane-bound ELISA kits. Both Borrelia-inoculated dogs and dogs vaccinated with B. burgdorferi bacterin developed levels of antibody detectable by the new IFA test. Dogs vaccinated with a combination canine vaccine or leptobacterin for food animal use developed detectable levels of antibody against Leptospira but remained seronegative for Borrelia by the new IFA test, as did the unvaccinated SPF dogs. The new IFA test was sensitive, detecting antibodies against B. burgdorferi as early as 7 days postinoculation. It was also specific, showing no cross-reactivity with anti-Leptospira antibodies induced by vaccination with leptobacterins. The new IFA test compared favorably with both the standardized traditional IFA test and ELISA. Results from both membrane-bound ELISA kits were not consistent when compared with each other or with the new IFA test. The new IFA test had low nonspecific fluorescence, which made it easier to evaluate and reduced the human error and variability of test results. AD - Department of Small Animal Internal Medicine, School of Veterinary Medicine, Tuskegee University, AL 36088, USA. PMID- 8744741 SO - J Vet Diagn Invest 1996 Apr;8(2):196-201 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 96332682 AU - Cerri D AU - Nuvoloni R AU - Ebani V AU - Pedrini A AU - Mani P AU - Andreani E AU - Farina R TI - Leptospira interrogans serovar hardjo in the kidneys and genital tracts of naturally infected sheep. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Bacteriuria/epidemiology/microbiology/veterinary MH - Carrier State/epidemiology/*veterinary MH - Female MH - Genital Diseases, Female/epidemiology/microbiology/*veterinary MH - Genitalia, Female/microbiology MH - Italy/epidemiology MH - Kidney/microbiology MH - Kidney Diseases/epidemiology/microbiology/*veterinary MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/epidemiology/immunology/microbiology/*veterinary MH - Sheep MH - Sheep Diseases/*epidemiology/microbiology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 960924 DP - 1996 Apr IS - 1121-7138 TA - New Microbiol PG - 175-8 SB - M CY - ITALY IP - 2 VI - 19 JC - CGC AA - Author EM - 9611 AB - A bacteriological study was carried out to identify possible renal and/or genital carriers of Leptospira interrogans serovar hardjo. L. hardjo was found at slaughter in the kidneys of three seropositive ewes, but not in uterus or salpinges of these animals. AD - Department of Animal Pathology, Prophylaxis and Food Hygiene, Faculty of Veterinary Medicine, University of Pisa, Italy. PMID- 8722315 SO - New Microbiol 1996 Apr;19(2):175-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 96306467 AU - Constans J AU - Gosse P AU - Cottarre M AU - Ansoborlo P AU - Mercie P AU - Etienne G AU - Conri O TI - [Myopericarditis and atrial fibrillation disclosing leptospirosis septicemia (letter; comment)] LA - Fre MH - Atrial Fibrillation/*etiology MH - Bacteremia/*complications/microbiology MH - Case Report MH - Human MH - Leptospirosis/blood/*complications MH - Male MH - Middle Age MH - Myocarditis/*etiology/microbiology PT - COMMENT PT - LETTER DA - 960919 DP - 1996 Mar 30 IS - 0755-4982 TA - Presse Med PG - 555 SB - X SB - M CY - FRANCE IP - 11 VI - 25 JC - PMT EM - 9611 CM - Comment on: Presse Med 1996 Nov 23;25(36):1805 RO - M:CNR PMID- 8731801 LR - 970414 TT - Myopericardite et fibrillation auriculaire revelatrice d'une leptospirose septicemique. SO - Presse Med 1996 Mar 30;25(11):555 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 96260136 AU - Dhaliwal GS AU - Murray RD AU - Ellis WA TI - Reproductive performance of dairy herds infected with Leptospira interrogans serovar hardjo relative to the year of diagnosis. LA - Eng MH - Abortion, Veterinary/epidemiology/*etiology MH - Animal MH - Cattle MH - *Cattle Diseases MH - Female MH - Fertility MH - Infertility, Female/etiology/*veterinary MH - Leptospira interrogans/classification/isolation & purification MH - Pregnancy MH - Support, Non-U.S. Gov't MH - Time Factors MH - Weil's Disease/complications/*veterinary PT - JOURNAL ARTICLE DA - 960912 DP - 1996 Mar 23 IS - 0042-4900 TA - Vet Rec PG - 272-6 SB - M CY - ENGLAND IP - 12 VI - 138 JC - XBS AA - Author EM - 9611 AB - To assess the impact of Leptospira interrogans serovar hardjo infection on the reproductive performance of nine dairy herds with evidence of infection, forty years' fertility data were analysed relative to the year of first diagnosis. Fifty per cent of various fertility variables had their lowest values only in the year of diagnosis. Culling rates were highest during the year of diagnosis in five of the herds, and were above 22 per cent in five of nine (55-6 per cent) of the diagnosis years considered compared with seven (22-6 per cent) of the 31 non- diagnosis years. An assessment of the fertility status of the herds by means of a formula with incorporated the first service conception rate, the number of services per conception for cows conceiving, the calving to conception interval and the culling rate, revealed low reproductive performance during the year of diagnosis in six of the nine herds. Abortion rates were highest in four of the herds during the year of diagnosis, and these included the herds in which the fertility status was not lowest. It was concluded that L. interrogans serovar hardjo affected reproductive adversely by causing both abortions and low fertility, but that the effect was temporary. AD - Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool Veterinary Field Station, Neston, South Wirral. PMID- 8711883 SO - Vet Rec 1996 Mar 23;138(12):272-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96260134 TI - Leptospirosis in farm animals [news] LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology/*prevention & control MH - Leptospirosis/epidemiology/prevention & control/*veterinary MH - Scotland/epidemiology MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases PT - NEWS DA - 960912 DP - 1996 Mar 23 IS - 0042-4900 TA - Vet Rec PG - 268 SB - M CY - ENGLAND IP - 12 VI - 138 JC - XBS EM - 9611 PMID- 8711882 NI - A SO - Vet Rec 1996 Mar 23;138(12):268 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 97352333 AU - Wu W AU - Bao L AU - Wu Q AU - Li S AU - Huang W AU - Wan B AU - Zhang M AU - Xiong Q AU - Fang Z TI - [16S rRNA gene PCR-SSCP analysis of the reference strains from 15 serovars (14 serogroups) of pathogenic leptospires in China] LA - Chi MH - China MH - English Abstract MH - Human MH - Leptospira interrogans/classification/*genetics MH - Polymerase Chain Reaction MH - *Polymorphism, Single-Stranded Conformational MH - RNA, Ribosomal, 16S/*genetics MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 970814 DP - 1996 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 17-20 CY - CHINA IP - 1 VI - 27 JC - GEB AA - Author EM - 9710 AB - The DNAs of reference strains from 15 serovars (14 serogroups) of pathogenic leptospires in China were amplified with 16S rRNA gene primers, and then single-strand conformation polymorphism (SSCP) of the products were analyzed in 12.5% nondenaturing mini polyacrylamide gel (containing 5% glycerol) combining with silver-staining. All products showed two bands on electrophoresis at different parameters of voltage or current and concentration of gel. It proved that serovar lai, serovar canicola, serovar pyrogenes, serovar autumnalis, serovar australis, serovar pomona, serovar linhai, serovar hebdomadis, serovar haemolytica, serovar wolffi and serovar paidjan have the identical pattern (Leptospira interrogans), while serovar javanica, serovar ballum, serovar tarassovi and serovar manhao I belong to another pattern (L. borgpetersenii). The result was consistent with the classification of genetic species by Yasuda et al (1987) and Ramadass et al (1992). AD - Research Unit of Leptospirasis, Chengdu. PMID- 9208613 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1996 Mar;27(1):17-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97352332 AU - Chen Z AU - Dai B AU - Yan H AU - Li S AU - Zhao H AU - Liu J AU - Song S AU - Yang Y AU - Zhang Y AU - Liu F AU - Tu Y AU - Yang H AU - Huang Z AU - Liang L AU - Hu L AU - Zhao M TI - [The PCR amplification, cloning, sequencing, expression in E. coli of gene encoding endoflagella subunit protein (fla B) from Leptospira interrogans serovar lai] LA - Chi MH - Amino Acid Sequence MH - Animal MH - Base Sequence MH - Cloning, Molecular MH - English Abstract MH - Escherichia coli/genetics MH - Flagellin/*biosynthesis/genetics MH - Gene Expression MH - *Genes, Bacterial MH - Leptospira interrogans/*genetics MH - Mice MH - Mice, Inbred BALB C MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - Random Allocation MH - Sequence Analysis, DNA MH - Support, Non-U.S. Gov't MH - Transfection RN - 12777-81-0 (Flagellin) RN - 140470-87-7 (flaB protein) PT - JOURNAL ARTICLE DA - 970814 DP - 1996 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 10-6 CY - CHINA IP - 1 VI - 27 JC - GEB AA - Author EM - 9710 AB - A pair of oligonucleotide primers were designed by ourselves to amplify the endoflagella gene of L. interrogans serovar lai. A fragment about 840 bp was generated with PCR and inserted into plasmid pUC8 after the fragment and pUC8 were digested respectively with Bam HI and Pst I. A recombinant plasmid (designated as pLF1) was obtained. SDS-PAGE analysis indicated that a 33 kd was expressed in E. coli JM103 harboring pLF1 and the expression level of the protein was 11% of total bacterial soluble proteins. Western blot analysis showed that the protein band could be recognized by the antiserum against the endoflagella (Axiall filament) of Leptospira interrogans serovar lai. Nucleotide seguence data showed an open reading frame encoding 282 aminoacids residues, corresponding to a protein of molecular weight 33.6 kd. The G + C content of endoflagella subunit protein gene was 48 mol%. Therefore, the G + C content of the leptospiral fla B Gene is significantly higher than the reported 39 mol% G + C content of leptospiral genome of L.interrogans serovar lai but similar to the G + C of the Treponema pallidum genome. Comparison of the deduced endoflagellar subunit protein (fla B) amino acid sequence with flagellins from other bacteria revealed a high level of identity with the Treponema pallidum fla B proteins. Immunization/protection experiment was performed on the model of BALB/c mice and showed that the survival rate in the group JM103-pLF1 was higher than that in the group JM103-pUC8, but statistically the difference between them was significant (P < 0.05) and pLF1 did not induce significant levels of agglutinating antibodies against L.interrogans serovar lai. AD - Research Group of I. West China University Medical Sciences, Chengdu. PMID- 9208612 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1996 Mar;27(1):10-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97013633 AU - Stabel JR AU - Goff JP AU - Whipple DL AU - Ackermann MR AU - Reinhardt TA TI - Low calcium diet and 1,25-dihydroxyvitamin D(3) infusion modulate immune responses during Mycobacterium paratuberculosis infection in beige mice. LA - Eng MH - Animal MH - Calcitriol/*administration & dosage/blood MH - Calcium/blood/metabolism MH - Calcium, Dietary/*administration & dosage MH - Colony Count, Microbial MH - Granuloma/immunology/metabolism MH - Ileum/drug effects/immunology/microbiology MH - Immunity/drug effects MH - Interleukin-1/biosynthesis MH - Liver/drug effects/immunology/microbiology MH - Lymphocyte Transformation/drug effects MH - Male MH - Mice MH - Mice, Inbred C57BL MH - Mice, Mutant Strains MH - Mycobacterium paratuberculosis/immunology/isolation & purification MH - Paratuberculosis/*immunology/metabolism/microbiology MH - Spleen/drug effects/immunology/microbiology MH - Time Factors RN - 0 (Calcium, Dietary) RN - 0 (Interleukin-1) RN - 32222-06-3 (Calcitriol) RN - 7440-70-2 (Calcium) PT - JOURNAL ARTICLE DA - 970519 DP - 1996 Mar IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 127-43 SB - M CY - NETHERLANDS IP - 1-2 VI - 50 JC - XCB AA - Author EM - 9707 AB - A 12-month study was conducted to evaluate the effects of feeding a low calcium (Ca) diet or 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3) infusion on the persistence of Mycobacterium paratuberculosis infection using a mouse model. Male beige mice 6-8 weeks of age were assigned to one of the following treatments: (1) non-infected, (2) infected,(3) non- infected/1,25(OH)(2)D(3), (4) infected/1,25(OH)(2)D(3), and (5) infected/low Ca (0.15 percent) diet. Infected mice were inoculated intravenously with live M. paratuberculosis. At 1, 6 and 12 months postinfection, mice in Treatments 3 and 4 were implanted subcutaneously with mini-osmotic pumps to deliver 1,25(OH)(2)D(3). Infusion with 1,25(OH)(2)D(3) exacerbated M. paratuberculosis infection in most tissues at all time points. Mice infused with 1,25(OH)(2)D(3) had higher bacterial counts in spleen, liver, and ileum compared with control infected mice after 1 month of infection. In contrast, feeding a low Ca diet reduced the number of viable organisms cultured from the liver and ileum of infected mice. Plasma Ca and 1,25(OH)(2)D(3) were increased in mice infused with 1,25(OH)(2)D(3) at all time points but values for low Ca mice were not different than for non-infused mice. Splenocyte production of TNF, IL-1 and IL-6 was higher for mice fed the low Ca diet compared with control infected mice after 1 month of infection. Inducible IL-6 activity remained higher for this treatment at 6 months postinfection. These results suggest that feeding a low Ca diet to mice chronically infected with M. paratuberculosis appears to enhance their ability to clear the infection in a manner distinct from any effect of 1,25(OH)2D3. AD - Leptospirosis and Mycobacteriosis Research Unit, National Animal Disease Center, Ames, IA 50010, USA. PMID- 9157678 SO - Vet Immunol Immunopathol 1996 Mar;50(1-2):127-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 97224652 AU - Silva MV AU - Camargo ED AU - Batista L AU - Vaz AJ AU - Ferreira AW AU - Barbosa PR TI - Application of anti-leptospira ELISA-IgM for the etiologic elucidation of meningitis. LA - Eng MH - Adolescence MH - Adult MH - Age Distribution MH - Antibodies, Bacterial/*cerebrospinal fluid MH - Child MH - Child, Preschool MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Human MH - IgM/analysis MH - Leptospira/immunology/*isolation & purification MH - Male MH - Meningitis/cerebrospinal fluid/*microbiology MH - Sex Distribution RN - 0 (Antibodies, Bacterial) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 970522 DP - 1996 Mar-Apr IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 153-6 CY - BRAZIL IP - 2 VI - 38 JC - S9D AA - Author EM - 9707 AB - Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomonuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis. AD - Institute of Tropical Medicine of Sao Paulo, Brazil. PMID- 9071036 SO - Rev Inst Med Trop Sao Paulo 1996 Mar-Apr;38(2):153-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 97161846 AU - Garrido R AU - Castillo L AU - Hernandez G AU - Abarca J AU - Montes JM AU - Monsalve V AU - Espinoza R AU - Valenzuela S AU - Perez G TI - [Systemic leptospirosis as a cause of multiple organ failure. Report of a case] LA - Spa MH - Abdominal Pain MH - Aged MH - Case Report MH - Cholestasis/surgery MH - Diagnostic Errors MH - English Abstract MH - Hemodiafiltration MH - Human MH - Intensive Care MH - Leptospirosis/*complications/diagnosis/therapy MH - Male MH - Multiple Organ Failure/diagnosis/*etiology/surgery MH - Penicillins/therapeutic use MH - Prognosis MH - Respiration, Artificial MH - Respiratory Insufficiency MH - Tomography, X-Ray Computed RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 970220 DP - 1996 Mar IS - 0034-9887 TA - Rev Med Chil PG - 359-62 CY - CHILE IP - 3 VI - 124 JC - SHD AA - Author EM - 9704 AB - Leptospirosis is a world-spread zoonosis that is incidentally acquired by humans. It causes a diphasic febrile illness in which the Weil syndrome is its severest form, with renal, hepatic, clotting and central nervous system involvement. We report a 73 years old male, that was admitted to an intensive care unit with multiple organ failure due to leptospirosis. The clinical picture initially resembled a sepsis due to biliary tract obstruction and was operated, not finding a biliary tract obstruction. Considering the history of a fall to sewed waters, leptospirosis was suspected and treatment with penicillin was started, obtaining a full recovery of the patient. AD - Departamento de Anestesiologia, Hospital Clinico, P Universidad Catolica, Santiago de Chile. PMID- 9008950 TT - Leptospirosis sistemica: una etiologia de falla multiorganica en un caso. EA - A SO - Rev Med Chil 1996 Mar;124(3):359-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 96247935 AU - Artois M AU - Claro F AU - Remond M AU - Blancou J TI - [Infectious pathology of Canidae and Felidae in zoological parks] LA - Fre MH - Animal MH - *Animals, Zoo MH - *Carnivora MH - Communicable Diseases/epidemiology/*veterinary MH - English Abstract MH - Human MH - Zoonoses PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 961118 DP - 1996 Mar IS - 0253-1933 TA - Rev Sci Tech PG - 115-40 SB - M CY - FRANCE IP - 1 VI - 15 JC - A9R AA - Author EM - 9701 AB - The Canidae (36 species) and Felidae (34-37 species) are two families of carnivores represented by numerous exotic species in zoos or wildlife reserves. To some extent, the diseases of these species are similar to those of dogs and cats, and are therefore relatively well known. However, there are differences in sensitivity to infectious agents, treatments and vaccines. Canidae and Felidae may also act as carriers or even vectors of zoonoses, such as leptospirosis, rabies, salmonellosis, toxoplasmosis and tuberculosis. Due to their behaviour patterns and morphological adaptations, these species are capable of transmitting various opportunistic infections by biting or scratching. These characteristics mean that Canidae and Felidae are difficult to keep in captivity, and require special health precautions, particularly protection from contact with stray carnivores. AD - Centre national d'etudes veterinaires et alimentaires, Nancy, France. RF - 50 PMID- 8924699 TT - Pathologie infectieuse des Canides et Felides des parcs zoologiques. EA - A SO - Rev Sci Tech 1996 Mar;15(1):115-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 96217073 AU - Bakoss P AU - Machacova E AU - Slacikova M TI - [Changes in the epidemiology of human leptospirosis in the Slovak Republic] LA - Slo MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Incidence MH - Leptospirosis/*epidemiology/microbiology MH - Male MH - Middle Age MH - Prevalence MH - Slovakia/epidemiology PT - JOURNAL ARTICLE DA - 960828 DP - 1996 Mar IS - 0006-9248 TA - Bratisl Lek Listy PG - 123-30 CY - SLOVAKIA IP - 3 VI - 97 JC - B5N AA - Author EM - 9610 AB - BACKGROUND. The epidemiologic patterns of infectious diseases are liable to change in the course of time. References to such changes in leptospirosis are very rare and of low systematic value. OBJECTIVES. The study is aimed at the detection of changes in the epidemiology of leptospirosis within the 20 years in Slovakia. METHODS. Basic epidemiologic characteristics of leptoospirosis were compared within two chronological periods. 598 registered cases were analyzed during the first period (1970-1976), and 200 cases of leptospirosis were analysed during the second period (1986-1991). MAIN RESULTS. The second period yielded a decrease in total incidence to approximately 50% (yearly average was 0.9/10(5) of the population). At the same time the cyclic character of morbidity has almost entirely disappeared. The incidence of leptospirosis has significantly decreased in the group of population between 40 and 59 years of age, thus causing a particular shift in morbidity towards the younger population. Cases of leptospirosis caused by L. tarassovi and L. canicola ceased to occur, however one case of infection caused by L. hardjo has been registered in the Slovak population. A significant decrease in the incidence of diseases caused by the Sejroe group serovars was detected, especially in housewives, retired people, industrial and agricultural workers. In contrast to the latter, the proportion of leptospirosis cases caused by L. icterohaemorrhagiae/copenhageni increased particularly in pupils and students, as well as those caused by L. pomona in slaughter-house workers. Consequently, the most dominating disease is represented by field fever (L. gripotyphosa), the second highest incidence is ascribed to Weil disease (L. icterohaemorrhagiae/copenhageni), while the incidence of infections caused by the group of Sejroe serovars dropped from the first to the fourth place. The possible reasons of these changes are presented. No changes in the incidence of leptospirosis according to sex and seasonal occurrence were registered. CONCLUSION. The results of this study are in accordance with the current knowledge of the development of epidemiologic signs of infectious diseases, including leptospirosis. The results provide a pattern of the current situation in the field of leptospirosis epidemiology in the territory of Slovakia and emphasize the importance of systematic surveillance enabling the assessment of appropriate measures suppressing these infections. (Fig. 7, Ref. 7.). AD - Ustav epidemiologie Lekarskej fakulty Univerzity Komenskeho v Bratislave, Slovakia. PMID- 8689314 TT - Zmeny epidemiologie leptospiroz l'udi v Slovenskej republike. EA - A SO - Bratisl Lek Listy 1996 Mar;97(3):123-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 96244145 AU - Dhaliwal GS AU - Murray RD AU - Dobson H AU - Montgomery J AU - Ellis WA TI - Presence of antigen and antibodies in serum and genital discharges of cows from dairy herds naturally infected with Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis/blood MH - Antigens, Bacterial/*analysis/blood/urine MH - Cattle MH - *Cattle Diseases MH - Cervix Uteri/*immunology MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - IgA/analysis/blood MH - IgG/analysis/blood MH - Leptospira interrogans/*immunology MH - Mucous Membrane/immunology MH - Support, Non-U.S. Gov't MH - Vagina/immunology MH - Weil's Disease/blood/immunology/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (IgA) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 960820 DP - 1996 Mar IS - 0034-5288 TA - Res Vet Sci PG - 163-7 SB - M CY - ENGLAND IP - 2 VI - 60 JC - R7D AA - Author EM - 9610 AB - Samples of cervico-vaginal mucus from 163 bulling cows (group 1) and post calving discharges from 59 newly calved cows (group 2) in five dairy herds naturally infected with Leptospira interrogans serovar hardjo were examined for the presence of antigen and IgG and IgA antibodies by using two ELISA systems which were protein or carbohydrate based. Corresponding serum samples were examined for systemic immune responses by using a microscopic agglutination test (MAT) and IgG-ELISA tests. Antigen was detected by direct immunofluorescence in six of the 163 samples of cervico-vaginal mucus. Both IgG and IgA antibodies were detected by ELISA in the genital discharges with a prevalence much higher than that obtained by the MAT but lower than that observed with the serum IgG-ELISA. Combining both groups, none of the MAT-positive cattle was negative by serum-ELISA. By using the protein or carbohydrate fraction serum IgG-ELISA assays, respectively, 29 or 41 per cent of the MAT-negative cows were positive at a titre of at least 1:40. Similarly, eight or 23 samples (10 or 27 per cent) had titres of at least 1:20 in the genital discharge ELISA for IgG and IgA antibodies, respectively. The serum IgG-ELISA was the most efficient in detecting hardjo antibodies, but in group 2 the IgG- and IgA-ELISA of the post calving discharge proved to be equally effective. AD - Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Leahurst, Neston, South Wirral. PMID- 8685539 SO - Res Vet Sci 1996 Mar;60(2):163-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 96244144 AU - Dhaliwal GS AU - Murray RD AU - Dobson H AU - Montgomery J AU - Ellis WA AU - Baker JR TI - Presence of antigen and antibodies in serum and genital discharges of heifers after experimental intrauterine inoculation with Leptospira interrogans serovar hardjo. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*blood MH - Antibody Formation MH - Antigens, Bacterial/*blood MH - Cattle MH - Cervix Uteri/immunology MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - IgA/blood MH - IgG/blood MH - Leptospira interrogans/*immunology/isolation & purification MH - Mucous Membrane/immunology MH - Pregnancy MH - *Pregnancy, Animal MH - Reference Values MH - Support, Non-U.S. Gov't MH - Urine/microbiology MH - Uterus MH - Vagina/immunology MH - Weil's Disease/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (IgA) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 960820 DP - 1996 Mar IS - 0034-5288 TA - Res Vet Sci PG - 157-62 SB - M CY - ENGLAND IP - 2 VI - 60 JC - R7D AA - Author EM - 9610 AB - The excretion of Leptospira interrogans serovar hardjo in cervico- vaginal mucus (CVM) or urine and the local and systemic immune responses to the organism were monitored in eight susceptible heifers after intrauterine inoculation while six similar heifers served as controls. All the heifers were inseminated at the subsequent oestrous periods. The overall percentage pregnancy rate (the number of pregnancies divided by the total number of inseminations) was lower in the infected heifers than in the controls though not significantly (33.3 v 50.0 per cent). Leptospires were detected, in either the urine or the CVM of six of the eight infected heifers during the study period of 15 weeks, either by direct immunofluorescence or dark ground microscopy; the bacteria did not grow in culture from any of the CVM samples. The control heifers remained free from evidence of infection. In the infected heifers, mean titres of at least 1:100 in a microscopic agglutination test were maintained for one to two weeks before declining to 1:10 to 1:30, whereas in serum IgG-ELISA tests (developed by using either protein or carbohydrate antigens), antibody titres of at least 1:100 were maintained throughout the study. During oestrous periods, IgA antibodies were detected more frequently in CVM with titres which were usually higher than the titres of IgG. AD - Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Leahurst, Neston, South Wirral. PMID- 8685538 SO - Res Vet Sci 1996 Mar;60(2):157-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 96247808 AU - Agunloye CA AU - Nash AS TI - Investigation of possible leptospiral infection in cats in Scotland. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Cat Diseases/blood/*epidemiology/microbiology MH - Cats MH - Female MH - Leptospira/immunology MH - Leptospirosis/complications/epidemiology/microbiology/*veterinary MH - Male MH - Prevalence MH - Scotland/epidemiology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 960822 DP - 1996 Mar IS - 0022-4510 TA - J Small Anim Pract PG - 126-9 SB - M CY - ENGLAND IP - 3 VI - 37 JC - K4N AA - Author EM - 9610 AB - Eighty-seven cats from the Glasgow area were investigated to determine the prevalence of leptospiral infection and possible resultant disease. Eight (9.2 per cent) of the cats reacted serologically with the antigens of three serovars. Five of the cats were seropositive to Leptospira hardjo, two to L autumnalis and one cat seroconverted to L icterohaemorrhagiae. A paired serum sample indicated a recent infection in one of the cats. The major clinical sign shown by this cat was ascites. Four of the cats were from rural areas. This appears to be the first report of a serological survey of leptospiral infection in cats in the Glasgow area. AD - Department of Veterinary Medicine, University of Glasgow Veterinary School. PMID- 8683955 SO - J Small Anim Pract 1996 Mar;37(3):126-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 96261275 AU - Abdollahpour G AU - English AW AU - Tasler J TI - Isolation of Leptospira interrogans serovar grippotyphosa from a heifer in New South Wales. LA - Eng MH - Animal MH - Antigens, Bacterial/analysis/blood/immunology MH - Cattle MH - Cattle Diseases/*diagnosis/epidemiology/immunology MH - Diagnosis, Differential MH - DNA, Bacterial/analysis/genetics MH - Female MH - Leptospira interrogans/*classification/genetics/immunology MH - Leptospirosis/diagnosis/epidemiology/*veterinary MH - New South Wales/epidemiology MH - Polymerase Chain Reaction/veterinary MH - Serotyping/veterinary MH - Species Specificity RN - 0 (Antigens, Bacterial) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 960730 DP - 1996 Mar IS - 0005-0423 TA - Aust Vet J PG - 109-10 SB - M CY - AUSTRALIA IP - 3 VI - 73 JC - 9IE EM - 9610 AD - Department of Animal Health, University of Sydney, New South Wales. PMID- 8660211 SO - Aust Vet J 1996 Mar;73(3):109-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [92 medline neighbors] UI - 96215527 AU - Bryan JP AU - Iqbal M AU - Ksiazek TG AU - Ahmed A AU - Duncan JF AU - Awan B AU - Krieg RE AU - Riaz M AU - Leduc JW AU - Nabi S AU - Qureshi MS AU - Malik IA AU - Legters LJ TI - Prevalence of sand fly fever, West Nile, Crimean-Congo hemorrhagic fever, and leptospirosis antibodies in Pakistani military personnel. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Hemorrhagic Fever, Crimean/*epidemiology MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - *Military Personnel MH - Pakistan/epidemiology MH - Phlebotomus Fever/*epidemiology MH - Prevalence MH - Seroepidemiologic Methods MH - West Nile Fever/*epidemiology PT - JOURNAL ARTICLE DA - 960710 DP - 1996 Mar IS - 0026-4075 TA - Mil Med PG - 149-53 CY - UNITED STATES IP - 3 VI - 161 JC - N1A AA - Author EM - 9609 AB - To determine the prevalence of antibodies to viral diseases known or suspected to be present in Pakistan, we studied 570 sera from three groups of adults; two of the groups were involved in outbreaks of hepatitis, and the third included men admitted to a hospital for evaluation of febrile illnesses. Immunoglobulin G antileptospiral antibody was found in 1 to 6% of the subjects, with the highest rate in enlisted military personnel hospitalized for febrile illness. One man in the group with febrile illness had significantly elevated immunoglobulin M antileptospiral antibody titers. However, in a group of recruits experiencing suspected non-A, non-B hepatitis, 19 (11%) of 173 had a 4-fold rise in immunoglobulin M antibody to leptospirosis. Antibody to sand fly fever viruses was found in 27 to 70%. Antibody to West Nile virus was present in 33 to 41% of subjects. Antibody reactive with Japanese encephalitis virus was present in 25%, but plaque reduction neutralization tests suggested this to be cross-reaction with West Nile virus. All 212 specimens tested for antibody to Crimean-Congo hemorrhagic fever and Hantaan viruses were negative. This study indicates that diseases known to be prevalent in other areas of southwest Asia and the Middle East are also prevalent in northern Pakistan and may impact on those traveling or working in this area. AD - Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799, USA. PMID- 8637643 SO - Mil Med 1996 Mar;161(3):149-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 96174716 AU - Zaki SR AU - Shieh WJ TI - Leptospirosis associated with outbreak of acute febrile illness and pulmonary haemorrhage, Nicaragua, 1995. The Epidemic Working Group at Ministry of Health in Nicaragua [letter] [see comments] LA - Eng MH - Diagnosis, Differential MH - *Disease Outbreaks MH - Fever/*epidemiology/etiology MH - Hemorrhage/*epidemiology/etiology MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/complications/diagnosis/*epidemiology MH - Lung Diseases/*epidemiology/etiology MH - Nicaragua/epidemiology PT - LETTER DA - 960418 DP - 1996 Feb 24 IS - 0140-6736 TA - Lancet PG - 535-6 SB - A SB - M SB - X CY - ENGLAND IP - 9000 VI - 347 JC - L0S EM - 9606 CM - Comment in: Lancet 1996 May 25;347(9013):1483-4 CM - Comment in: Lancet 1996 Jun 1;347(9014):1562-3 RO - M:LC2 PMID- 8596276 LR - 961006 SO - Lancet 1996 Feb 24;347(9000):535-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 96252848 AU - Wittenbrink MM AU - Failing K AU - Krauss H TI - Enzyme-linked immunosorbent assay and immunoblot analysis for detection of antibodies to Borrelia burgdorferi in dogs. The impact of serum absorption with homologous and heterologous bacteriae. LA - Eng MH - Animal MH - Antibodies, Bacterial/*blood MH - Antigens, Bacterial/immunology MH - Blotting, Western MH - Borrelia burgdorferi/*immunology MH - Dog Diseases MH - Dogs/*immunology/microbiology MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Ixodes MH - Lyme Disease/diagnosis/veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 970311 DP - 1996 Feb IS - 0378-1135 TA - Vet Microbiol PG - 257-68 SB - M CY - NETHERLANDS IP - 3-4 VI - 48 JC - XBW AA - Author EM - 9705 AB - Sera from 665 apparently healthy dogs were examined for antibodies to the Lyme disease spirochete Borrelia (B.) burgdorferi by using an ELISA with a whole cell sonicate of B. burgdorferi sensu stricto reference strain B31 (ATCC 35210) as antigen. To discover false positive reactions due to the unsatisfactory specificity of conventional enzyme- linked immunosorbent assays for B. burgdorferi, sera were absorbed in parallel with both B. burgdorferi and a heterologous sorbent consisting of whole cells of Escherichia coli, Salmonella typhimurium, and eight serovars of Leptospira interrogans. The difference between optical densities obtained in the ELISA after serum absorption with the heterologous sorbent and the B. burgdorferi sorbent was defined as a new value, "ODdiff", for ELISA reactivity specific for B. burgdorferi. ELISA results were confirmed by immunoblot studies. By testing unabsorbed sera, 48 of 665 serum samples (7.2%) were considered ELISA positive. 37 of these 48 sera (77.1%) were apparently false positive: here a similar reduction of ELISA reactivity was obtained after absorption with B. burgdorferi antigen and with the heterologous sorbent (ODdiff approximately equal to 0). None of these 37 sera gave immunoblot patterns characteristic for canine B. burgdorferi infection. AD - Institut fur Hygiene und Infektionskrankheiten der Tiere, Justus-Liebig- Universitat Giessen, Germany. PMID- 9054122 SO - Vet Microbiol 1996 Feb;48(3-4):257-68 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 97036419 AU - Constantin A AU - Marin F AU - Oksman F AU - Bouteiller G TI - Antineutrophil cytoplasmic antibodies in leptospirosis. LA - Eng MH - Aged MH - Antibodies, Antineutrophil Cytoplasmic/*analysis MH - Biological Markers MH - Case Report MH - Human MH - Leptospirosis/*immunology MH - Male RN - 0 (Antibodies, Antineutrophil Cytoplasmic) RN - 0 (Biological Markers) PT - JOURNAL ARTICLE DA - 961217 DP - 1996 Feb IS - 0315-162X TA - J Rheumatol PG - 411 SB - M CY - CANADA IP - 2 VI - 23 JC - JWX EM - 9702 AD - Centre Hospitalier General, Toulouse, France. PMID- 8882067 SO - J Rheumatol 1996 Feb;23(2):411 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 96381015 AU - Bolin CA AU - Zuerner RL TI - Correlation between DNA restriction fragment length polymorphisms in Leptospira interrogans serovar pomona type kennewicki and host animal source. LA - Eng MH - Animal MH - Animals, Wild/microbiology MH - Cattle/microbiology MH - Comparative Study MH - Disease Outbreaks/veterinary MH - DNA, Bacterial/*genetics/isolation & purification MH - Epidemiology, Molecular MH - Horses/microbiology MH - Leptospira interrogans/classification/*genetics/isolation & purification MH - *Polymorphism, Restriction Fragment Length MH - Serotyping MH - Swine/microbiology MH - Weil's Disease/epidemiology/microbiology/veterinary MH - Zoonoses/epidemiology/microbiology RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 961021 DP - 1996 Feb IS - 0095-1137 TA - J Clin Microbiol PG - 424-5 SB - M CY - UNITED STATES IP - 2 VI - 34 JC - HSH AA - Author EM - 9612 AB - Isolates (n = 147) of Leptospira interrogans serovar pomona type kennewicki from cattle, swine, horses, and wildlife were analyzed by DNA restriction endonuclease analysis. Restriction fragment length polymorphisms were identified in DNA digested with HpaII, and the restriction fragment length polymorphisms were correlated with the host animal source of the isolates. These results will be useful in understanding the epidemiology of serovar pomona infections in livestock. AD - Leptospirosis and Mycobacteriosis Research Unit, National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa 50010, USA. a03rllmr@attmail.com PMID- 8789028 SO - J Clin Microbiol 1996 Feb;34(2):424-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 96261263 AU - Corney BG AU - McClintock CS AU - Colley J AU - Elder JK TI - Genotypes of Leptospira isolated from Queensland cattle. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology/urine MH - Female MH - Genotype MH - Leptospira/classification/*genetics/isolation & purification MH - Leptospirosis/microbiology/urine/*veterinary MH - Queensland PT - JOURNAL ARTICLE DA - 960729 DP - 1996 Feb IS - 0005-0423 TA - Aust Vet J PG - 75-6 SB - M CY - AUSTRALIA IP - 2 VI - 73 JC - 9IE EM - 9610 AD - Rockhampton Veterinary Laboratory, Department of Primary Industries, Queensland. PMID- 8660206 SO - Aust Vet J 1996 Feb;73(2):75-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [98 medline neighbors] UI - 97213307 AU - Leblebicioglu H AU - Sencan I AU - Sunbul M AU - Altintop L AU - Gunaydin M TI - Weil's disease: report of 12 cases. LA - Eng MH - Adult MH - Aged MH - Antibodies, Bacterial/blood MH - Female MH - Human MH - Male MH - Middle Age MH - Penicillins/therapeutic use MH - Rural Population MH - Turkey/epidemiology MH - Weil's Disease/drug therapy/*epidemiology/*physiopathology RN - 0 (Antibodies, Bacterial) RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 970520 DP - 1996 IS - 0036-5548 TA - Scand J Infect Dis PG - 637-9 SB - M CY - SWEDEN IP - 6 VI - 28 JC - UCX AA - Author EM - 9707 AB - The epidemiological distribution and clinical features of 12 cases of Weil's disease from Turkey, are reviewed. The disease is most common in male farmers from rural areas. Myalgia and jaundice were recorded in all patients. Signs included vomiting in 9 patients, haemorrhages in 6, and renal function was impaired in 6. Creatine phosphokinase levels were found above normal limits in 75% of the cases. Leptospires were demonstrated with dark-field microscopy in the blood of 9 and in the urine of 5 of these patients. The diagnosis was confirmed with microscopic agglutination test (MAT) as well as with ELISA. Ig M antibodies were detected in 11 (92%) of the patients and is an accurate marker for acute leptospirosis. Penicillin was used for therapy and the outcome was favorable in 10 patients. Two patients died. It should be kept in mind that leptospirosis is an extremely severe disease which requires appropriate examinations at the right moment. AD - Department of Clinical Microbiology and Infectious Diseases, Ondokuz Mayis University Medical School, Samsun, Turkey. PMID- 9060072 SO - Scand J Infect Dis 1996;28(6):637-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 97199885 AU - Shimizu K AU - Morimoto S TI - [Spirochaeta! myocarditis] LA - Jpn MH - Borrelia burgdorferi/isolation & purification MH - Human MH - Leptospira interrogans/isolation & purification MH - *Lyme Disease MH - Myocarditis/*microbiology MH - *Syphilis, Cardiovascular MH - Treponema pallidum/isolation & purification MH - *Weil's Disease PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 970321 DP - 1996 TA - Ryoikibetsu Shokogun Shirizu PG - 158-60 CY - JAPAN IP - 14 JC - CAY EM - 9705 AD - Department of Internal Medicine, Fujita Health University School of Medicine. RF - 16 PMID- 9047821 SO - Ryoikibetsu Shokogun Shirizu 1996;(14):158-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 97147402 AU - Shuvalova EP AU - Antonova TV AU - Alekseeva EA TI - [The significance of lipid peroxidation in the pathogenesis of leptospirosis and its complications] LA - Rus MH - Antioxidants/analysis MH - Comparative Study MH - English Abstract MH - Human MH - Kidney Failure, Acute/blood/etiology MH - Leptospirosis/*blood/complications/etiology MH - *Lipid Peroxidation MH - Lipid Peroxides/blood MH - Liver Failure, Acute/blood/etiology MH - Malondialdehyde/blood MH - Prognosis MH - Shock, Septic/blood/etiology MH - Time Factors RN - 0 (Antioxidants) RN - 0 (Lipid Peroxides) RN - 542-78-9 (Malondialdehyde) PT - JOURNAL ARTICLE DA - 970304 DP - 1996 IS - 0040-3660 TA - Ter Arkh PG - 38-40 SB - M CY - RUSSIA IP - 11 VI - 68 JC - VLU AA - Author EM - 9705 AB - Lipid peroxidation (LPO) and antioxidant plasma activity were evaluated in 39 patients with leptospiral jaundice. At the height of the disease LPO proceeded more actively, being the highest in cases of severe complications. Early in the disease course general antioxidant activity of plasma was inhibited significantly more noticeably in complicated versus uncomplicated leptospirosis. This confirms pathogenetic implication of membrane LPO in leptospirosis. The approaches to prognostication of the disease course and completeness of the response are proposed. PMID- 9045376 TT - Znachenie perekisnogo okisleniia lipidov v patogeneze leptospiroza i ego oslozhnenii. EA - A SO - Ter Arkh 1996;68(11):38-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 97114161 AU - Perret JL AU - Velasque L AU - Morillon M AU - Martet G TI - [Leptospirosis: a cause of pseudo-malarial fever in Gabon] LA - Fre MH - Adolescence MH - Adult MH - Antibodies, Bacterial/blood MH - Diagnosis, Differential MH - English Abstract MH - *Fever MH - France/ethnology MH - Gabon MH - Human MH - IgM/blood MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/immunology MH - *Malaria, Falciparum MH - Male MH - Military Personnel RN - 0 (Antibodies, Bacterial) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 970117 DP - 1996 TA - Bull Soc Pathol Exot PG - 217-9 SB - M CY - FRANCE IP - 3 VI - 89 JC - BK9 AA - Author EM - 9703 AB - A first case of leptospirosis has been recently described in Gabon where bioclimatological characteristics could favour the transmission of that disease. Therefore, a search for antibodies to leptospirae was conducted among 55 military Frenchmen with unexplained fever during a four-month stay in Gabon. Three (5.5%) were positive with IgM levels attesting for recent contamination. A screening antigenic battery identified L. bataviae in two cases and L. sejroe in one case. The three patients were employed outside in the precedent weeks. Travelers are exposed to leptospirosis in numerous Third-World countries. Clinical and biological similarities between leptospirosis and P. falciparum malaria could induce misdiagnosis. Co-infection could also be encountered. Doxycycline, whose activity against P. falciparum is well known, is also effective against leptospirae. Therefore, this drug seems valuable for prophylactic and therapeutic actions in areas exposed to the both diseases. AD - Service de medecine interne et pathologie infectieuse et tropicale, HIA Laveran, Marseille-Armees. PMID- 8998419 TT - Leptospirose: une cause de fievre pseudo-palustre au Gabon. EA - A SO - Bull Soc Pathol Exot 1996;89(3):217-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 96425912 AU - Andreescu N TI - [The receptivity to Leptospira icterohaemorrhagiae infection in the Romanian population] LA - Rum MH - Adolescence MH - Adult MH - Agglutination Tests MH - Aging/immunology MH - Antibodies, Bacterial/blood MH - Child MH - Disease Susceptibility MH - Female MH - Human MH - Leptospira interrogans/immunology MH - Male MH - Middle Age MH - Romania MH - Sex Characteristics MH - Weil's Disease/*immunology/prevention & control RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 961202 DP - 1996 Jan-Jun TA - Bacteriol Virusol Parazitol Epidemiol PG - 29-31 CY - ROMANIA IP - 1-2 VI - 41 JC - BFP EM - 9702 AD - Institutul Cantacuzino. PMID- 8963112 TT - Studiul receptivitatii la infectia cu Leptospira icterohaemorrhagiae a populatiei din Romania. SO - Bacteriol Virusol Parazitol Epidemiol 1996 Jan-Jun;41(1-2):29-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 97088771 AU - Masuzawa T AU - Nakamura R AU - Beppu Y AU - Yanagihara Y TI - Immunochemical characteristics and localization on cells of protective antigen (PAg) prepared from Leptospira interrogans serovar lai. LA - Eng MH - Antigens, Bacterial/*immunology/isolation & purification MH - Blotting, Western MH - Chromatography, Affinity MH - Epitopes/chemistry MH - Formic Acids/metabolism MH - Hydrolysis MH - Leptospira interrogans/*chemistry/immunology/ultrastructure MH - Microscopy, Immunoelectron MH - Oxidation-Reduction RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) RN - 0 (Formic Acids) PT - JOURNAL ARTICLE DA - 970124 DP - 1996 IS - 0385-5600 TA - Microbiol Immunol PG - 237-41 SB - M CY - JAPAN IP - 3 VI - 40 JC - MX7 AA - Author EM - 9704 AB - Immuno-electron microscopic methods revealed that the protective antigen (PAg) of Leptospira interrogans serovar lai exists on the outer envelope sheathing the leptospiral cell body. PAg lost its protective activity after treatment by hydrolysis with 2 M formic acid at 100 C for 2 hr, or oxidation with periodate at 4 C for 40 hr. The antigenic oligosaccharide fraction was further purified from the hydrolyzed PAg by immunoaffinity column coupled with protective monoclonal antibody, LW2, and by gel filtration of HPLC. The antigenic oligosaccharide fraction contained two unknown sugars and 4-O-methylmannose (molar ratio 3:5:1). These findings suggested that these sugars are components of an antigenic determinant contributing to the protective immunity against serovar lai infection. AD - Department of Microbiology, University of Shizuoka, Japan. PMID- 8934679 SO - Microbiol Immunol 1996;40(3):237-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 97087723 AU - Hartskeerl RA AU - Terpstra WJ TI - Leptospirosis in wild animals. LA - Eng MH - Animal MH - *Animals, Wild MH - Cattle MH - Chiroptera MH - Deer MH - Hamsters MH - Hedgehogs MH - Lagomorpha MH - *Leptospira MH - Leptospirosis/epidemiology/*veterinary MH - Mice MH - Microtinae MH - Netherlands/epidemiology MH - Rats MH - Shrews MH - Swine PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 970227 DP - 1996 IS - 0165-2176 TA - Vet Q PG - S149-50 SB - M CY - NETHERLANDS VI - 18 Suppl 3 JC - XBT EM - 9705 AD - Royal Tropical Institute, N.H. Swellengretel-laboratorium, Amsterdam, The Netherlands. RF - 12 PMID- 8933702 SO - Vet Q 1996;18 Suppl 3:S149-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 96402605 AU - Rathinamsivakumar AU - Ratnam S AU - Sureshbabu L AU - Natarajaseenivasan K TI - Leptospiral antibodies in patients with recurrent ophthalmic involvement. LA - Eng MH - Adult MH - Antibodies, Bacterial/*analysis MH - Human MH - India MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/immunology MH - Male MH - Middle Age MH - Panuveitis/diagnosis/*microbiology MH - Retinal Diseases/diagnosis/*microbiology MH - Vasculitis/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 961025 DP - 1996 Jan IS - 0971-5916 TA - Indian J Med Res PG - 66-8 CY - INDIA VI - 103 JC - GJF AA - Author EM - 9701 AB - Leptospiral antibodies could be demonstrated by microscopic agglutination test in 14 of 15 (93%) patients with acute panuveitis and retinal vasculitis in a preliminary study undertaken during the postmonsoon period at Madurai in Tamilnadu, India. The predominant serogroup was Pomona followed by Autumnalis, Australis and Javanica, the titres being between 1:160 and 1:10240. Titres in the normal controls were 1:20 to 1:80 in 8 of 20 mostly to the endemic serogroup Autumnalis. The involvement of leptospires particularly Pomona as a cause of ophthalmic complications in the patients studied is likely. AD - Aravind Eye Hospital, Madurai. PMID- 8926031 SO - Indian J Med Res 1996 Jan;103:66-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [97 medline neighbors] UI - 96402598 AU - John TJ TI - Emerging & re-emerging bacterial pathogens in India. LA - Eng MH - Animal MH - Anthrax/epidemiology/veterinary MH - Bacterial Infections/*epidemiology MH - Cattle MH - Cholera/epidemiology MH - *Disease Outbreaks MH - Drug Resistance, Multiple MH - Human MH - India MH - Leptospirosis/epidemiology MH - Melioidosis/epidemiology/veterinary MH - Plague/epidemiology MH - Rats PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 961025 DP - 1996 Jan IS - 0971-5916 TA - Indian J Med Res PG - 4-18 CY - INDIA VI - 103 JC - GJF AA - Author EM - 9701 AB - In spite of major successes against infectious diseases in the 20th century, new infectious diseases have emerged and old ones re-emerged in recent decades in different parts of the world. A brief survey of emerging and re-emerging bacterial diseases of public health importance in India is presented in this paper. Plague re-appeared in two outbreaks in Maharashtra and Gujarat in 1994, indicating a breakdown of the public health measures that had prevented its occurrence for several decades. Leptospirosis appears to be on the increase in Kerala, Tamilnadu and the Andamans during the last 2 decades, probably due to increased farming and inadequate rodent control. It is suggested that melioidosis due to the soil organism Burkholderia pseudomallei may be prevalent in many parts of India, but is under-diagnosed and under- reported. Since 1991, a completely new choleragenic Vibrio cholerae, designated 0139 has emerged in southern India and spread to other parts of India and to neighbouring countries, setting in motion the 8th cholera pandemic. Animal anthrax is very common in many parts of India, but human anthrax is recognised in only certain limited locations. In the Chittoor and North Arcot districts, its prevalence had increased in recent years. Since 1990, a multi-drug resistant variety of typhoid fever had been prevalent in many parts of India, caused by Salmonella typhi resistant to chloramphenicol, ampicillin and trimethoprim- sulphamethoxazole. Nosocomial methicillin-resistant Staphylococcus aureus infection seems to be widely prevalent in hospitals in many regions in India, and its prevalence seems to be on the rise. These pathogens pose new threats to public health, and call for appropriate responses. Microbiological expertise and epidemiological surveillance are deficient in the health care and public health systems in India; therefore even infections and diseases that have been under control elsewhere remain prevalent in the country, but are also under-diagnosed and under-reported. Without improving microbiological expertise and application as well as epidemiological skills and practices, emerging and re-emerging diseases may not be recognised, identified or intercepted in their early stages. AD - Department of Microbiology, Christian Medical College & Hospital, Vellore. RF - 74 PMID- 8926026 SO - Indian J Med Res 1996 Jan;103:4-18 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 97064072 AU - Brandling-Bennett AD AU - Penheiro F TI - Infectious diseases in Latin America and the Caribbean: are they really emerging and increasing? [editorial] LA - Eng MH - Cholera/*epidemiology MH - Dengue/*epidemiology MH - Encephalomyelitis, Venezuelan Equine/*epidemiology MH - Human MH - Latin America/epidemiology MH - Leptospirosis/*epidemiology PT - EDITORIAL DA - 961206 DP - 1996 Jan-Mar IS - 1080-6040 TA - Emerg Infect Dis PG - 59-61 SB - M CY - UNITED STATES IP - 1 VI - 2 JC - COD EM - 9702 PMID- 8903199 SO - Emerg Infect Dis 1996 Jan-Mar;2(1):59-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 97003907 AU - Tavares-Neto J AU - Andrade J AU - Hofer E AU - de Oliveira GF AU - Couto-Junior A TI - [The frequency of agglutinins for Leptospira seen in the inhabitants of Uberaba, Minas Gerais] LA - Por MH - Adult MH - Agglutinins/*blood MH - Brazil/epidemiology MH - Female MH - Human MH - Incidence MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/immunology MH - Male MH - Middle Age MH - Risk Factors MH - Seroepidemiologic Methods MH - *Urban Population/statistics & numerical data RN - 0 (Agglutinins) PT - JOURNAL ARTICLE DA - 961209 DP - 1996 Jan-Feb IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 55-8 CY - BRAZIL IP - 1 VI - 29 JC - RET EM - 9702 AD - Faculdade de Medicina da Universidade Federal da Bahia, Salvador, BA. PMID- 8851218 TT - Frequencia de aglutininas para Leptrospira observadas em habitantes de Uberaba, Minas Gerais. SO - Rev Soc Bras Med Trop 1996 Jan-Feb;29(1):55-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 96417901 AU - Pupkevich-Diamant IaS TI - [The results of the study of the pathogenesis and pathophysiology of the leptospiral infectious process and its clinical manifestations] LA - Rus MH - Human MH - Leptospira/pathogenicity MH - Leptospirosis/diagnosis/*etiology/microbiology/physiopathology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 961204 DP - 1996 Jan-Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 100-4 SB - M CY - RUSSIA IP - 1 JC - Y9O EM - 9702 AD - Novocherkassk, Russia. RF - 47 PMID- 8820692 TT - Nekotorye itogi izucheniia patogeneza i patofiziologii leptospiroznogo infektsionnogo protsessa i ego klinicheskikh proiavlenii. SO - Zh Mikrobiol Epidemiol Immunobiol 1996 Jan-Feb;(1):100-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [13 medline neighbors] UI - 96244650 AU - Goodman SA TI - USDA: progress toward in vitro tests and other trends. LA - Eng MH - Animal MH - Animal Testing Alternatives/*legislation & jurisprudence/*trends MH - Bacterial Vaccines/pharmacology/standards MH - Biological Products/isolation & purification/*pharmacology/*standards MH - Clostridium/immunology MH - Diarrhea Virus, Bovine Viral/immunology MH - Erysipelothrix/immunology MH - Escherichia coli/immunology MH - In Vitro MH - Leptospira/immunology MH - Reference Standards MH - Safety MH - Tetanus Antitoxin/pharmacology MH - United States MH - United States Department of Agriculture MH - Viral Vaccines/pharmacology/standards RN - 0 (Bacterial Vaccines) RN - 0 (Biological Products) RN - 0 (Tetanus Antitoxin) RN - 0 (Viral Vaccines) PT - JOURNAL ARTICLE DA - 960925 DP - 1996 IS - 0301-5149 TA - Dev Biol Stand PG - 41-7 SB - M CY - SWITZERLAND VI - 86 JC - E7V AA - Author EM - 9611 AB - The Animal and Plant Health Inspection Service of the United States Department of Agriculture has demonstrated a commitment toward replacement, reduction and refinement of animal use in the development and control of biological products. This presentation describes some specific approaches with which APHIS has reduced the number of animals used in testing by replacing host or laboratory animal potency tests with validated in vitro tests, reduced the number of animals required for tests by allowing sequential use of animals for tests of immunologically distinct entities, and replaced host or laboratory animal challenge studies with serological tests. It also describes APHIS' plans to reduce pain and suffering of animals by allowing euthanasia when death from causes unrelated to the test is expected. Finally, it reports on refinements in extraneous agent testing, which began when host animal tests were replaced with an in vitro test method and continued when the in vitro test was replaced with a more sensitive status of these approaches is discussed in the context of APHIS' current regulatory framework. AD - USDA, APHIS, BBEP Veterinary Biologics, Hyattsville, MD, USA. PMID- 8785990 SO - Dev Biol Stand 1996;86:41-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [53 medline neighbors] UI - 96244697 AU - Ruby KW AU - Walden DM AU - Wannemuehler MJ TI - Development of an in vitro assay for measuring the relative potency of leptospiral bacterins containing serovar canicola and its correlation to the hamster potency assay. LA - Eng MH - Animal MH - Animal Testing Alternatives/methods MH - Antibodies, Monoclonal MH - Bacterial Vaccines/*analysis MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay/*methods MH - Hamsters MH - Leptospira/*immunology/pathogenicity MH - Virulence RN - 0 (Antibodies, Monoclonal) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 960925 DP - 1996 IS - 0301-5149 TA - Dev Biol Stand PG - 341 SB - M CY - SWITZERLAND VI - 86 JC - E7V EM - 9611 AD - National Veterinary Services Laboratories, USDA/APHIS, Ames, IA 50010, USA. PMID- 8785981 SO - Dev Biol Stand 1996;86:341 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 96244696 AU - Ruby KW TI - Evaluation of the Leptospira pomona ELISA and its correlation with the hamster potency assay. LA - Eng MH - Animal MH - Animal Testing Alternatives/methods MH - Bacterial Vaccines/*analysis/pharmacology MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay/*methods MH - Hamsters MH - Leptospira/*immunology RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 960925 DP - 1996 IS - 0301-5149 TA - Dev Biol Stand PG - 340 SB - M CY - SWITZERLAND VI - 86 JC - E7V EM - 9611 AD - National Veterinary Services Laboratories, USDA/APHIS, Ames, IA 50010, USA. PMID- 8785980 SO - Dev Biol Stand 1996;86:340 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96378314 AU - de Queiroz-Leite LT AU - Resende M AU - Ramos-Vieira M das N AU - Cota-Koury M TI - Experimental immunization of hamsters with an EDTA extract of Leptospira interrogans, serovar icterohaemorrhagiae. LA - Eng MH - Agglutinins/biosynthesis/immunology MH - Animal MH - Antibodies, Bacterial/biosynthesis/immunology MH - Antigens, Bacterial/administration & dosage/*immunology/isolation & purification MH - Bacterial Vaccines/administration & dosage/*immunology/isolation & purification MH - Dose-Response Relationship, Immunologic MH - Edetic Acid MH - Evaluation Studies MH - Hamsters MH - Injections, Subcutaneous MH - Kidney/microbiology MH - Leptospira interrogans/chemistry/classification/*immunology/isolation & purification MH - Leptospirosis/immunology/*prevention & control MH - Lipopolysaccharides/administration & dosage/*immunology/isolation & purification MH - Mesocricetus MH - Solvents MH - Support, Non-U.S. Gov't MH - *Vaccination RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (Lipopolysaccharides) RN - 0 (Solvents) RN - 60-00-4 (Edetic Acid) PT - JOURNAL ARTICLE DA - 961203 DP - 1996 Jan-Mar IS - 0187-4640 TA - Rev Latinoam Microbiol PG - 39-43 CY - MEXICO IP - 1 VI - 38 JC - SEP AA - Author EM - 9702 AB - The EDTA extract was prepared from the Leptospira interrogans serovar icterohaemorrhagiae. When inoculated subcutaneously in hamsters it conferred protection from challenge with virulent leptospires with a low dose (10 micrograms/ml) and low agglutinating antibody (40). The protection of animals obtained by the EDTA extract opens up the perspective of its use as a component of a vaccine for the control of leptospirosis. AD - Departamento de Microbiologia, Universidade Federal de Minas Gerais, Brazil. PMID- 8783904 SO - Rev Latinoam Microbiol 1996 Jan-Mar;38(1):39-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 96319068 AU - De Brito T AU - Sandoval MP AU - Silva AG AU - Saad RC AU - Colaiacovo W TI - Intestinal spirochetosis: first cases reported in Brazil and the use of immunohistochemistry as an aid in histopathological diagnosis. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Aged, 80 and over MH - Biopsy MH - Brazil/epidemiology MH - Case Report MH - Child MH - Child, Preschool MH - Colon/microbiology/*ultrastructure MH - Colonic Diseases/microbiology/*pathology MH - Female MH - Human MH - Immunohistochemistry MH - Infant MH - Intestinal Mucosa/microbiology/ultrastructure MH - Male MH - Microscopy, Electron MH - Microscopy, Electron, Scanning MH - Middle Age MH - Rectum/microbiology/*ultrastructure MH - Spirochaetales/*ultrastructure MH - Spirochaetales Infections/*diagnosis/epidemiology/microbiology MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 961217 DP - 1996 Jan-Feb IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 45-52 CY - BRAZIL IP - 1 VI - 38 JC - S9D AA - Author EM - 9702 AB - Colonization of the colon and rectum by intestinal spirochetes is detected for the first time in Brazil in 4 of 282 (1.41%) patients who had undergone sigmoidoscopy and/or colonoscopy with a histopathological diagnosis of chronic non specific-colitis. This frequency is probably underestimated, since surgically obtained specimens were not considered in the present study. Histopathological diagnosis was performed using routine stains like hematoxylin-eosin which showed the typical, of 3- microns thick hematoxyphilic fringe on the brush border of the surface epithelium, and by silver stains like the Warthin-Starry stain. Immunohistochemical procedures using two, polyclonal, primary antibodies, one against Treponema pallidum and the other against Leptospira interrogans serovar copenhageni serogroup Icterohaemorrhagiae cross-reacted with spirochetal antigen/s producing a marked contrast of the fringe over the colonic epithelium, preserving the spiral-shaped morphology of the parasite. In one case with marked diarrhea, immunohistochemistry detected spirochetal antigen/s within a cell in an intestinal crypt, thus demonstrating that the infection can be more widely disseminated than suspected using routine stains. Immunohistochemical procedures, thus, greatly facilitate the histological diagnosis of intestinal spirochetosis and may contribute to a better understanding of the pathogenesis of the disease. Transmission and scanning electron microscopy performed in one case showed that the spirochete closely resembled the species designated as Brachyspira aalborgi. AD - Institute of Tropical Medicine and University Hospital, University of S. Paulo Medical School, Brazil. PMID- 8762639 SO - Rev Inst Med Trop Sao Paulo 1996 Jan-Feb;38(1):45-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 96333780 AU - Huang G AU - Lin T TI - Bacterial L-forms research in China. LA - Eng MH - Animal MH - Human MH - L Forms/*isolation & purification MH - Leptospira/*isolation & purification MH - Mycobacterium tuberculosis/*isolation & purification MH - Streptococcus pyogenes/*isolation & purification MH - Ureaplasma/isolation & purification PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 970311 DP - 1996 Jan IS - 0366-6999 TA - Chin Med J (Engl) PG - 18-20 CY - CHINA IP - 1 VI - 109 JC - D3B EM - 9705 AD - Department of Microbiology, Bengbu Medical College, Anhui. RF - 0 PMID- 8758352 SO - Chin Med J (Engl) 1996 Jan;109(1):18-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 96351913 AU - Alt DP AU - Bolin CA TI - Preliminary evaluation of antimicrobial agents for treatment of Leptospira interrogans serovar pomona infection in hamsters and swine. LA - Eng MH - Animal MH - Antibiotics/*pharmacology MH - Comparative Study MH - Female MH - Hamsters MH - Kidney/microbiology/pathology MH - Leptospira interrogans/classification/isolation & purification MH - Mesocricetus MH - Species Specificity MH - Swine MH - *Swine Diseases MH - Weil's Disease/drug therapy/pathology/*veterinary RN - 0 (Antibiotics) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - RANDOMIZED CONTROLLED TRIAL DA - 970310 DP - 1996 Jan IS - 0002-9645 TA - Am J Vet Res PG - 59-62 SB - M CY - UNITED STATES IP - 1 VI - 57 JC - 40C AA - Author EM - 9705 AB - OBJECTIVE: To evaluate antimicrobial agents for treatment of models of acute and persistent leptospirosis caused by Leptospira interrogans serovar pomona. DESIGN: Randomized trials comparing dosages and regimens of various antimicrobial agents for treatment of acute and persistent leptospirosis. ANIMALS: 245 Golden hamsters to model acute leptospirosis and 121 mixed-breed swine to model persistent leptospirosis. PROCEDURE: Hamsters and swine were inoculated with L interrogans serovar pomona. Antimicrobial agents were given to hamsters for 3 or 5 days after inoculation, with necropsy at 14 days after inoculation. Swine were treated for 1, 3, or 5 days beginning at 3 weeks after inoculation, and were necropsied 7 to 10 days after completion of antimicrobial agent treatment. Hamster tissue and swine tissue and urine specimens were examined by culture, fluorescent antibody testing, and histologic examination for presence of leptospires. RESULTS: All untreated control hamsters became infected and manifested clinical signs and lesions of acute leptospirosis. Leptospires were not detected in hamsters treated with dihydrostreptomycin/penicillin G (25 mg/kg of body weight). Administration of ampicillin at all dosages reduced the number of hamsters infected, as confirmed at necropsy; the other agents tested required dosages greater than label recommendations to reduce the number infected. All untreated control swine became infected and shed leptospires in urine through the time of necropsy. Leptospires were not detected in kidneys or urine of swine treated with dihydrostreptomycin/penicillin G (25 mg/kg) for 1, 3, or 5 days, or in swine treated with oxytetracycline (40 mg/kg for 3 or 5 days), tylosin (44 mg/kg for 5 days), or erythromycin (25 mg/kg for 5 days). Treatment with ceftiofur and ampicillin was not effective in elimination of L interrogans serovar pomona in swine. CONCLUSIONS: Dihydrostreptomycin/penicillin G is effective for treatment of acute and persistent leptospirosis. Differences between the effectiveness of antimicrobial agents in the acute and persistent model of leptospirosis emphasize the importance of using the appropriate model for treatment evaluation. Antimicrobial agents evaluated for treatment of persistent leptospirosis in swine required the use of dosages above those recommended by the manufacturer. CLINICAL RELEVANCE: Use of antimicrobial agents at extra-label dosages for treatment of persistent leptospirosis may cause residue problems in food animals; however, these regimens may be useful for treatment of breeding stock or animals destined for import/export. AD - National Animal Disease Center, USDA, Ames, IA 50010, USA. PMID- 8720239 SO - Am J Vet Res 1996 Jan;57(1):59-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 96241237 AU - Achacha M AU - Mittal KR TI - Identification and characterization of genus-specific epitopes of Serpulina species using monoclonal antibodies. LA - Eng MH - Animal MH - Antibodies, Monoclonal/biosynthesis MH - Antigens, Bacterial/*isolation & purification MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Hybridomas MH - Serpulina/*immunology MH - Species Specificity MH - Spirochaetales Infections/immunology/microbiology/*veterinary MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*immunology/microbiology RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 960903 DP - 1996 Jan IS - 0378-1135 TA - Vet Microbiol PG - 73-85 SB - M CY - NETHERLANDS IP - 1-2 VI - 48 JC - XBW AA - Author EM - 9611 AB - Four murine monoclonal antibodies (mAbs) designated as C9E8, A10, G12, and G8 which recognized both Serpulina hyodysenteriae and S. innocens were produced and characterized. The mAbs reacted with whole cell antigens in ELISA, indirect immunofluorescence and immunoblot assays. The mAbs did not show any cross reactivity in rapid dot ELISA or immunoblot assay with Leptospira icterohemorrhagiae, Campylobacter jejuni and Escherichia coli. Treatment of whole cell suspension with proteinase K and sodium periodate indicated that the reacting epitopes of the mAbs were protein in nature. The genus-specific antigens were identified as heat-stable proteins with molecular weight in the range of 26 to 45 kDa. Immunofluorescence and immunogold labelling studies showed that the antibody-binding epitopes were exposed on the outer- surface of the spirochaetal cell wall. The mAbs inhibited growth of reference strains of both S. hyodysenteriae and S. innocens in vitro but failed to cause agglutination. The detection of spirochaetal forms directly in fecal smears or paraffin-embeded tissue sections from experimentally infected pigs indicated that such mAbs were potentially useful for the diagnosis of swine spirochaetosis. This is the first report of mAbs identifying and characterizing common antigens of porcine Serpulina. AD - Departement de Pathologie et Microbiologie, Universite de Montreal, Quebec, Canada. PMID- 8701579 SO - Vet Microbiol 1996 Jan;48(1-2):73-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 96233345 AU - Egorov IIa AU - Maramovich AS AU - Makeev SM AU - Cherniavskii VF AU - Trop IE AU - Tugutov LD TI - [The epidemiological and epizootiological characteristics of leptospirosis in the Republic of Sakha (Yakutia)] LA - Rus MH - Adult MH - Animal MH - Animals, Domestic MH - Animals, Wild MH - Disease Reservoirs/statistics & numerical data/veterinary MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology/*veterinary MH - Male MH - Middle Age MH - Retrospective Studies MH - Siberia/epidemiology PT - JOURNAL ARTICLE DA - 960905 DP - 1996 Jan-Mar IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 48-51 CY - RUSSIA IP - 1 JC - M72 AA - Author EM - 9611 AB - Among zoonotic infections with natural foci in the Republic of Sakha (Yakutia), leptospiroses have assumed greater importance. Their morbidity is sporadic, mainly afflicting rural adults. The serogroups pomona, grippotyphosa, and icterohaemorrhagiae are prevalent in the etiological structure of leptospiras. An epizootiological survey has revealed natural and anthropurgic leptospirosis foci which present a hazard primarily to rural inhabitants who deal with animal husbandry, fur-bearer breeding, hunting, and fishing. The vole (Microtis) and root vole (Microtis oeconomus) serve as the major reservoir and source of leptospiroses in the natural foci, while cattle and caged Arctic foxes do in the anthropurgic ones. High sizes of house and grey mice which are carriers of the Leptospira javanica and icterohaemorrhagiae, have been recorded in the residential and domestic constructions of localities. A complex of antileprospirotic measures that limits the influence of the leading factors of infection transmission and the risk of human infection is substantiated. PMID- 8700015 TT - Epidemiologicheskaia i epizootologicheskaia kharakteristika leptospirozov v respublike Sakha (Iakutiia). EA - A SO - Med Parazitol (Mosk) 1996 Jan-Mar;(1):48-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 96207758 AU - Abdulkader RC AU - Seguro AC AU - Malheiro PS AU - Burdmann EA AU - Marcondes M TI - Peculiar electrolytic and hormonal abnormalities in acute renal failure due to leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Blood Pressure MH - Corticotropin/blood MH - Electrolytes/*blood MH - Female MH - Follow-Up Studies MH - Hormones/*blood MH - Human MH - Kidney/physiopathology MH - Kidney Failure, Acute/etiology/*metabolism MH - Kidney Tubular Necrosis, Acute/metabolism MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Potassium/blood RN - 0 (Electrolytes) RN - 0 (Hormones) RN - 7440-09-7 (Potassium) RN - 9002-60-2 (Corticotropin) PT - JOURNAL ARTICLE DA - 960725 DP - 1996 Jan IS - 0002-9637 TA - Am J Trop Med Hyg PG - 1-6 SB - A SB - M CY - UNITED STATES IP - 1 VI - 54 JC - 3ZQ AA - Author EM - 9609 AB - Hypokalemia in leptospirosis acute renal failure (ARF) was studied in nine patients with severe leptospirosis ARF and five patients with moderate leptospirosis ARF and compared with five patients with severe acute tubular necrosis (ATN) and eight healthy individuals. Urinary volumes of both the severe and moderate leptospirosis groups were higher than those of the severe ATN group. Leptospirosis groups had serum potassium levels lower than those found in the healthy and severe ATN groups. Serum sodium levels were lower in the severe leptospirosis group than in the moderate leptospirosis, the severe ATN, and the healthy groups. There was a positive correlation between the fractional excretion of sodium and potassium in the severe leptospirosis group as well as between serum creatinine and potassium levels in the pooled leptospirosis groups. Urinary pH in the severe and moderate leptospirosis groups was lower than in the severe ATN group. Aldosterone levels were higher in the severe leptospirosis group than in the healthy individuals. Cortisol levels were higher in the leptospirosis groups than in the healthy subjects. These results strongly suggest that hypokalemia in leptospirosis ARF is due to renal potassium wasting potentialized by aldosterone and cortisol, requiring that special attention is given to potassium replacement as well as to volume repletion in the treatment of leptospirosis ARF. AD - Laboratorio de Fisiopatologia Renal, Disciplina de Nefrologia, Faculdade de Medicina, Universidade de Sao Paulo, Brazil. PMID- 8651360 SO - Am J Trop Med Hyg 1996 Jan;54(1):1-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 96222190 AU - Frolov VM AU - Peresadin NA AU - Baklanova AV TI - [Clinical assessment of autoimmune and immunocomplex reactions in patients with leptospirosis] LA - Rus MH - *Antigen-Antibody Complex MH - *Autoimmunity MH - Bilirubin/blood MH - Human MH - Leptospirosis/blood/*immunology RN - 0 (Antigen-Antibody Complex) RN - 635-65-4 (Bilirubin) PT - JOURNAL ARTICLE DA - 960719 DP - 1996 IS - 0023-2149 TA - Klin Med (Mosk) PG - 68 CY - RUSSIA IP - 1 VI - 74 JC - KW2 EM - 9609 PMID- 8649020 TT - Klinicheskaia otsenka autoimmunnykh i immunokompleksnykh reaktsii u bol'nykh leptospirozom. SO - Klin Med (Mosk) 1996;74(1):68 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 96208194 AU - Bender LC AU - Hall PB TI - Leptospira interrogans exposure in free-ranging elk in Washington. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood/urine MH - Carrier State/epidemiology/*veterinary MH - *Deer MH - Female MH - Leptospira interrogans/classification/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/epidemiology/*veterinary MH - Prevalence MH - Support, Non-U.S. Gov't MH - Washington/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 960624 DP - 1996 Jan IS - 0090-3558 TA - J Wildl Dis PG - 121-4 SB - M CY - UNITED STATES IP - 1 VI - 32 JC - KEM AA - Author EM - 9608 AB - Exposure to one or more serovars of Leptospira interrogans was observed in five of six sampled elk (Cervus elaphus roosevelti) killed in November 1993, from an isolated herd in southwest Washington, USA (46 degrees 45'N, 123 degrees 6'W). In April 1994, exposure to L. interrogans serovars was documented in nine of 11 captured cow elk from the same herd. Leptospires were not isolated from any of the exposed elk, and 10 of the 11 cows were pregnant. The high seroprevalence is evidence that exposure is widespread in the herd. Local productivity of elk was high, however, and the surrounding topography was not conducive for transmission to other elk populations. AD - Washington Department of Fish and Wildlife, Vancouver 98663, USA. PMID- 8627923 SO - J Wildl Dis 1996 Jan;32(1):121-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 96165151 AU - Nicol AG AU - Wright ME AU - Prentice AC AU - Carroll A AU - Kemp S AU - Reed JM TI - Need for vaccination of sewer workers against leptospirosis and hepatitis A [letter; comment] LA - Eng MH - Hepatitis A/*prevention & control MH - Human MH - Leptospirosis/*prevention & control MH - *Vaccination PT - COMMENT PT - LETTER DA - 960304 DP - 1996 Jan IS - 1351-0711 TA - Occup Environ Med PG - 71 SB - M CY - ENGLAND IP - 1 VI - 53 JC - BWC EM - 9605 CM - Comment on: Occup Environ Med 1995 Aug;52(8):505-7 RO - M:LC2 PMID- 8563863 LR - 960507 SO - Occup Environ Med 1996 Jan;53(1):71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [3 protein links] [1 nucleotide link] [117 medline neighbors] UI - 96144301 AU - Stamm LV AU - Frye JG AU - Hardham JM TI - Sequence of the Leptospira biflexa serovar patoc recA gene. LA - Eng MH - Amino Acid Sequence MH - Base Sequence MH - DNA, Bacterial/genetics MH - *Genes, Structural, Bacterial MH - Leptospira/*genetics MH - Molecular Sequence Data MH - Promoter Regions (Genetics) MH - Rec A Protein/*genetics MH - Regulatory Sequences, Nucleic Acid MH - Sequence Homology, Amino Acid MH - Support, U.S. Gov't, P.H.S. RN - 0 (DNA, Bacterial) RN - 0 (Rec A Protein) PT - JOURNAL ARTICLE ID - 1 UO1 AI31496/AI/NIAID DA - 960301 DP - 1995 Dec 29 IS - 0378-1119 TA - Gene PG - 339-40 SB - M CY - NETHERLANDS IP - 1-2 VI - 167 JC - FOP AA - Author EM - 9605 AB - The nucleotide (nt) sequence of the recA gene of Leptospira biflexa serovar patoc strain Patoc I has been determined. The deduced amino acid (aa) sequence of the RecA protein is 387 aa long with a predicted molecular mass of 42,355 Da. The aa sequence has a high degree of identity to the aa sequences of many bacterial RecA, including Pseudomonas fluorescens, Escherichia coli and Bacillus subtilis. This is the first recA sequence reported for a bacterium in the order Spirochaetales. AD - Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599, USA. PMID- 8566806 SI - GENBANK/U32625 SO - Gene 1995 Dec 29;167(1-2):339-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 96088922 TI - From the Centers for Disease Control and Prevention. Outbreak of acute febrile illness and pulmonary hemorrhage--Nicaragua, 1995. LA - Eng MH - Acute Disease MH - *Disease Outbreaks MH - Fever/etiology MH - Hemorrhage/etiology MH - Human MH - Leptospirosis/complications/*epidemiology MH - Lung Diseases/etiology MH - Nicaragua/epidemiology PT - JOURNAL ARTICLE DA - 951226 DP - 1995 Dec 6 IS - 0098-7484 TA - JAMA PG - 1668 SB - A SB - M SB - X CY - UNITED STATES IP - 21 VI - 274 JC - KFR EM - 9602 PMID- 7474259 NI - A SO - JAMA 1995 Dec 6;274(21):1668 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96140524 AU - Swiader L AU - Disdier P AU - Retornaz F AU - Pauzier F AU - Harle JR AU - Weiller PJ TI - [Jarisch-Herxheimer reaction in leptospirosis (letter)] LA - Fre MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*diagnosis MH - Male PT - LETTER DA - 960212 DP - 1995 Dec 2 IS - 0755-4982 TA - Presse Med PG - 1753 SB - M SB - X CY - FRANCE IP - 37 VI - 24 JC - PMT EM - 9604 PMID- 8545419 TT - Reactions de Jarisch-Herxheimer au cours d'une leptospirose. SO - Presse Med 1995 Dec 2;24(37):1753 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 97206475 AU - Kiatboonsri S AU - Vathesatogit P AU - Charoenpan P TI - Adult respiratory distress syndrome in Thai medical patients. LA - Eng MH - Adult MH - Age Distribution MH - Female MH - Hospital Mortality MH - Human MH - Male MH - Middle Age MH - Positive-Pressure Respiration MH - Prospective Studies MH - Respiratory Distress Syndrome, Adult/*etiology/mortality/*therapy MH - Risk Factors MH - Survival Analysis MH - Thailand MH - Treatment Outcome PT - JOURNAL ARTICLE DA - 970502 DP - 1995 Dec IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 774-80 SB - M CY - THAILAND IP - 4 VI - 26 JC - UVN AA - Author EM - 9707 AB - Adult respiratory distress syndrome (ARDS) has been a well recognized severe form of acute respiratory failure of multiple causes, which is characterized by intractable hypoxemia and an extremely high mortality rate. Forty-six cases of ARDS admitted to the Department of Medicine, Ramathibodi Hospital during a 39 months period were studied prospectively to explore the etiologic risk, positive end-expiratory pressure (PEEP) profiles, complications and outcome of treatment. There were 19 females and 27 males with the mean age of 40 years. Risks of ARDS included intra- and extra-pulmonary disease conditions and also tropical diseases such as malaria and leptospirosis. At the time of diagnosis, patients in this group were extremely hypoxic with a mean arterial/alveolar oxygen tension (PaO2/PAO2) of 0.125 +/- 0.04. After the application of appropriate PEEP, the mean PaO2/PAO2 ratios increased significantly in both survivor and non-survivor groups (0.277 and 0.199). The levels of PEEP used were below 16 and 11 cmH2O in 93.46% and 67.38% of cases, respectively. Complications of PEEP which included barotrauma and hypotension were found in 11 cases (23.9%) with a very high mortality rate (81.8%). There were 28 deaths of patients in this study, giving an overall 60.8% group mortality rate. Despite the similarities in most clinical profiles, the survivors, when compared to the non-survivors, showed a greater extent of improved oxygenation in response to the application of PEEP, with fewer PEEP complications. The present study would, hopefully, provide the Thai clinicians with valuable informations in the management of ARDS. AD - Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. PMID- 9139393 SO - Southeast Asian J Trop Med Public Health 1995 Dec;26(4):774-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 97015025 AU - Ciceroni L AU - Pinto A AU - Benedetti E AU - Pizzocaro P AU - Lupidi R AU - Cinco M AU - Gelosa L AU - Grillo R AU - Rondinella V AU - Marcuccio L AU - et al TI - Human leptospirosis in Italy, 1986-1993. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agglutination Tests MH - Antibodies, Bacterial/isolation & purification MH - Child MH - Child, Preschool MH - Female MH - Human MH - Infant MH - Italy/epidemiology MH - Leptospirosis/*epidemiology/immunology/transmission MH - Male MH - Middle Age MH - Seroepidemiologic Methods MH - Weil's Disease/*epidemiology/immunology/transmission RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 970605 DP - 1995 Dec IS - 0392-2990 TA - Eur J Epidemiol PG - 707-10 SB - M CY - NETHERLANDS IP - 6 VI - 11 JC - ERE AA - Author EM - 9708 AB - In the eight-year period 1986-1993, the Italian National Center for Leptospirosis and the Regional Leptospira Laboratories confirmed 312 cases of clinical leptospirosis by using the microscopic agglutination (MA) assay. The majority of cases was observed in Northern regions of the Country. Cases were reported in all age groups, but were most common in the working-age population. Of 312 cases, 291 (93.3%) occurred among males. The largest number of infections was ascribed to occupational activities (45.8%). The typical leptospiral seasonal course, with a peak during the summer, was observed. Involvement of the liver was the most frequent manifestation. Influenza-like symptoms were the only signs of illness in 11.1% of cases. Anti-leptospira antibodies, cross-reacting with two or more serovars, were found in 28.2% of sera. The most frequent serovar-specific antibodies were those against poi, icterohaemorrhagiae, bratislava, copenhageni and sejroe. AD - National Center for Leptospirosis, Istituto Superiore di Sanita, Rome, Italy. PMID- 8861858 SO - Eur J Epidemiol 1995 Dec;11(6):707-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 96357851 AU - Richardson GF AU - Spangler E AU - MacAulay EB TI - A serological survey of four Leptospira serovars in dairy cows on Prince Edward Island. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*epidemiology/immunology/microbiology MH - Data Collection MH - Female MH - Leptospira/*classification/immunology MH - Leptospirosis/epidemiology/immunology/microbiology/*veterinary MH - Prevalence MH - Prince Edward Island/epidemiology MH - Seroepidemiologic Methods MH - Serotyping/veterinary MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 961022 DP - 1995 Dec IS - 0008-5286 TA - Can Vet J PG - 769-70 SB - M CY - CANADA IP - 12 VI - 36 JC - CLS EM - 9612 AD - Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown. PMID- 8748447 SO - Can Vet J 1995 Dec;36(12):769-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 96331959 AU - Chen Z AU - Dai B AU - Zhang Y AU - Li S TI - [Construction of genomic library of L. interrogans serovar lai and preliminary study of recombinant plasmid pDC38] LA - Chi MH - DNA, Recombinant MH - English Abstract MH - *Genome, Bacterial MH - *Genomic Library MH - Leptospira interrogans/*genetics MH - Plasmids MH - Support, Non-U.S. Gov't RN - 0 (DNA, Recombinant) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 961010 DP - 1995 Dec IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 357-60 CY - CHINA IP - 4 VI - 26 JC - GEB AA - Author EM - 9612 AB - A genomic library, consisting of approximate 12 000 recombinants, has been constructed for the Leptospira interrogans serovar lai in E. coli. using pUC18 as the vector. Hybridization analysis with the DNA fragment containing OmpL1 gene was performed and 10 positive clones were screened from the genomic library. One of the positive clones, designated pDC38, showed hybridization signal with the DNA of 7 serovars 8 strains of pathogenic leptospires, but not with the DNA of nonpathogenic leptospires (L. biflexa), Leptonama illini, E. coli., and 2 strains of L. interrongans. AD - Department of Pathophysiology, Sichuan University. PMID- 8732051 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1995 Dec;26(4):357-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 96329728 AU - Pan ZA AU - He QY TI - [The sero-epidemiological investigation of leptospirosis in Hainan Province] LA - Chi MH - Adult MH - Animal MH - China/epidemiology MH - English Abstract MH - Female MH - Human MH - Incidence MH - Leptospirosis/*epidemiology MH - Male MH - Rats MH - Seroepidemiologic Methods MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 961205 DP - 1995 Dec IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 369-71 CY - CHINA IP - 6 VI - 16 JC - CQG AA - Author EM - 9702 AB - This paper reported that 529 serum samples were collected from healthy people in ten townships of nine cities or counties of Hainan Province in 1993 and anti-leptospira antibody was examined. Results showed that 274 cases were positive (51.8%), indicating the natural infection rates were from 25.9% to 72.2% in different areas. The infection was irrelevant to sex, but was interrelated to age and occupations. There were 15 serogroups of anti-leptospira antibody identified in this study. Bataviae, Grippotyphosa and Icterohaemorrhagiae serogroups were the dominant serogroups, different from that the Grippotyphosa and Autumnalis serogroups as the superior serogroups in the 1970s. Data shows that the main epidemic serogroups are likely to change, which suggests that the surveillance of leptospirosis needs to be strengthened. AD - Hygiene and Anti-epidemic Station of Hainan Province, Haikou. RO - M:CNR PMID- 8728960 LR - 970707 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1995 Dec;16(6):369-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 96193080 AU - Potts AD AU - Lotter C AU - Robinson JT TI - Serological prevalence of leptospiral antibodies in pigs in South Africa. LA - Eng MH - Animal MH - Antibodies, Bacterial/*blood MH - Leptospirosis/diagnosis/*veterinary MH - Seroepidemiologic Methods MH - South Africa/epidemiology MH - Swine MH - Swine Diseases/diagnosis/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 960802 DP - 1995 Dec IS - 0030-2465 TA - Onderstepoort J Vet Res PG - 281-4 SB - M CY - SOUTH AFRICA IP - 4 VI - 62 JC - OI6 AA - Author EM - 9610 AB - A serological survey for leptospiral antibodies was carried out on 5 041 abattoir pigs from different regions in South Africa. Antibodies to at least one serovar were detected in 22,2% of the animals. The serovars showing the highest prevalence were: icterohaemorrhagiae (12,6%), hardjo (12,1%) and bratislava (7,5%). The serum dilution level at which 90% of the sera reacted was 1/80 or 1,160. AD - Onderstepoort Veterinary Institute, South Africa. PMID- 8668327 SO - Onderstepoort J Vet Res 1995 Dec;62(4):281-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 96156144 AU - Zuerner RL AU - Alt D AU - Bolin CA TI - IS1533-based PCR assay for identification of Leptospira interrogans sensu lato serovars [published erratum appears in J Clin Microbiol 1997 Mar;35(3):802] LA - Eng MH - Animal MH - Bacterial Typing Techniques MH - Base Sequence MH - Cattle MH - *DNA Insertion Elements MH - DNA Primers/genetics MH - DNA, Bacterial/genetics/urine MH - Gene Amplification MH - Human MH - Leptospira interrogans/classification/*genetics/isolation & purification MH - Molecular Sequence Data MH - Polymerase Chain Reaction/*methods MH - Serotyping MH - Variation (Genetics) MH - Weil's Disease/diagnosis/microbiology RN - 0 (DNA Insertion Elements) RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 960327 DP - 1995 Dec IS - 0095-1137 TA - J Clin Microbiol PG - 3284-9 SB - M CY - UNITED STATES IP - 12 VI - 33 JC - HSH AA - Author EM - 9605 AB - A PCR-based assay was developed for typing L. interrogans sensu lato serovars. The assay is designed to exploit the presence of many copies of the leptospiral insertion sequence IS1533 and IS1533-like sequences present in the genomes of most leptospiral serovars. The PCR primers were designed to amplify DNA of unknown sequence between closely placed IS1533 or IS1533-like sequences. Amplification reactions primed with IS1533-based primers generated products of different sizes. When few copies of IS1533 were present in the genome, amplification of a few products was still detected. These results suggest that IS1533 elements may be found close together. Analysis of DNA amplified from different serovars showed the presence of differently sized products, thus enabling the serovars to be identified. Genetic variation among isolates within the same serovar was also demonstrated with the IS1533- based primers. Amplification reactions using DNA extracted from the urine of infected animals generated specific products which were similar to the products generated from purified bacterial DNA. These results demonstrate that this assay is selective enough to be used for typing leptospiral serovars from clinical material and thus allows leptospiral typing without isolation of the bacteria in pure culture. AD - Leptospirosis and Mycobacteriosis Research Unit, U.S. Department of Agriculture, Ames, Iowa 50010, USA. rzuerner@asrr.arsusda.gov RO - M:MWS PMID- 8586718 LR - 971001 SO - J Clin Microbiol 1995 Dec;33(12):3284-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 96135116 AU - Ribeiro MA AU - Souza CC AU - Almeida SH TI - Dot-ELISA for human leptospirosis employing immunodominant antigen. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/*immunology MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay/*methods MH - Evaluation Studies MH - Hepatitis/immunology MH - Human MH - IgM/analysis MH - Immunodominant Epitopes/*immunology MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/immunology MH - Malaria, Falciparum/immunology MH - Sensitivity and Specificity MH - Serodiagnosis MH - Syphilis/immunology MH - Typhoid/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (IgM) RN - 0 (Immunodominant Epitopes) PT - JOURNAL ARTICLE DA - 960212 DP - 1995 Dec IS - 0022-5304 TA - J Trop Med Hyg PG - 452-6 SB - M CY - ENGLAND IP - 6 VI - 98 JC - KAV AA - Author EM - 9604 AB - A dot enzyme-linked immunosorbent assay which uses a proteinase-K resistant antigen (PK-Dot-ELISA) to detect antileptospiral IgM antibodies was compared to the microscopic agglutination test (MAT). The assay was evaluated in serum samples from patients with leptospirosis (n = 89), typhoid fever (n = 10), malaria (n = 19), syphilis (n = 20), hepatitis (n = 16) and clinically healthy individuals (n = 92). The PK-Dot-ELISA presented a sensitivity of 92.1% and a specificity of 97.5%. The overall results of the PK-Dot-ELISA were similar to those of the MAT. However, the PK-Dot-ELISA was capable of detecting antibody activity in 43% of acute-phase sera which were negative by the MAT. Our data suggest that PK-Dot-ELISA can be used as an important portable field serodiagnostic assay for acute leptospirosis. AD - Adolfo Lutz Institute, Sao Paulo Health Service, Brazil. PMID- 8544230 SO - J Trop Med Hyg 1995 Dec;98(6):452-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 96062672 AU - Dwyer AE AU - Crockett RS AU - Kalsow CM TI - Association of leptospiral seroreactivity and breed with uveitis and blindness in horses: 372 cases (1986-1993). LA - Eng MH - Age Distribution MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/blood MH - Blindness/etiology/genetics/*veterinary MH - Breeding MH - Female MH - Horse Diseases/*etiology/genetics MH - Horses MH - Leptospira interrogans/immunology MH - Leptospirosis/complications/*veterinary MH - Male MH - Ophthalmoscopy/veterinary MH - Retrospective Studies MH - Sex Distribution MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Uveitis/etiology/genetics/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE ID - EY 06866/EY/NEI DA - 951130 DP - 1995 Nov 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1327-31 SB - M CY - UNITED STATES IP - 10 VI - 207 JC - HAV AA - Author EM - 9602 AB - Recurrent uveitis, a leading cause of blindness in horses, often develops as a sequela to systemic leptospirosis. Over a 7-year period, 63 of 112 (56%) horses with uveitis were seropositive for Leptospira interrogans serovar pomona, but only 23 of 260 (9%) horses without uveitis were seropositive. Odds-ratio analysis revealed that seropositive horses were 13.2 times more likely to have uveitis than were seronegative horses. Of the 63 seropositive horses with uveitis, 59% developed blindness, compared with only 24% in the 49 seronegative horses with uveitis that lost vision in 1 or both eyes during the same period. Odds-ratio analysis revealed that seropositive horses with uveitis were 4.4 times more likely to lose vision than were seronegative horses with uveitis. Of the 112 horses with uveitis, 28 (25%) were Appaloosas, compared with only 10 of the 260 (4%) horses without uveitis (odds ratio, 8.3). In addition, 19 of the 28 (68%) Appaloosas with uveitis developed blindness, compared with only 30 of the 84 (36%) non-Appaloosas with uveitis that lost vision in 1 or both eyes (odds ratio, 3.8). This field study therefore confirmed a strong positive relationship between uveitis and leptospiral seroreactivity in horses. Furthermore, the data suggested that seropositive horses with uveitis were at increased risk of losing vision, compared with that in seronegative horses with uveitis, and that Appaloosas were at increased risk of developing uveitis and associated blindness, compared with that in non-Appaloosas. AD - Genesee Valley Equine Clinic, Scottsville, NY 14546, USA. PMID- 7591929 SO - J Am Vet Med Assoc 1995 Nov 15;207(10):1327-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 96064875 AU - Epstein PR AU - Calix Pena O AU - Blanco Racedo J TI - Climate and disease in Colombia. LA - Eng MH - Aged MH - Child MH - *Climate MH - Colombia MH - Dengue/*epidemiology MH - *Disease Outbreaks MH - Encephalomyelitis, Venezuelan Equine/*epidemiology MH - Eutrophication MH - Human MH - Leptospirosis/*epidemiology MH - Water Pollution/statistics & numerical data PT - JOURNAL ARTICLE DA - 951215 DP - 1995 Nov 11 IS - 0140-6736 TA - Lancet PG - 1243-4 SB - A SB - M SB - X CY - ENGLAND IP - 8985 VI - 346 JC - L0S EM - 9602 AD - Harvard School of Public Health New Disease Group, Cambridge Hospital, MA, USA. PMID- 7475711 SO - Lancet 1995 Nov 11;346(8985):1243-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96131013 TI - Leptospirosis identified in Nicaragua. LA - Eng LA - Fre MH - Human MH - Leptospirosis/*epidemiology/mortality/prevention & control MH - Nicaragua/epidemiology PT - JOURNAL ARTICLE DA - 960208 DP - 1995 Nov 10 IS - 0049-8114 TA - Wkly Epidemiol Rec PG - 322 CY - SWITZERLAND IP - 45 VI - 70 JC - AVX EM - 9604 PMID- 8534596 NI - A SO - Wkly Epidemiol Rec 1995 Nov 10;70(45):322 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 96402740 AU - Rivera E AU - Concha C AU - Braganca M AU - Gunnarsson A AU - Karlsson KA TI - Acute outbreak of porcine parvovirus infection in Mozambique. LA - Eng MH - Abortion, Veterinary/epidemiology/etiology MH - Animal MH - Antibodies, Viral/analysis/immunology MH - *Disease Outbreaks MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Female MH - Mozambique/epidemiology MH - Parvoviridae Infections/complications/epidemiology/*veterinary MH - *Parvovirus/immunology/isolation & purification MH - Pregnancy MH - Swine MH - Swine Diseases/*epidemiology RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 961203 DP - 1995 Nov IS - 0049-4747 TA - Trop Anim Health Prod PG - 217-20 SB - M CY - SCOTLAND IP - 4 VI - 27 JC - WG2 AA - Author EM - 9702 AB - Investigations were made to determine the causal agent of an acute outbreak of abortions recorded in a swine herd in Mozambique. Isolation of porcine parvovirus and demonstration of its specific antibodies accomplished by using enzyme-linked immunosorbent assay, haemagglutination inhibition and immunofluorescent tests, indicated that porcine parvovirus was the causal agent of the abortions. Other pathogenic agents causing reproductive failure, e.g. pseudorabies virus, Leptospira or Brucella species, were ruled out because investigations of these agents proved to be negative. AD - National Veterinary Institute, Uppsala, Sweden. PMID- 8966762 SO - Trop Anim Health Prod 1995 Nov;27(4):217-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 96092135 AU - Brem S AU - Radu O AU - Bauer T AU - Schonberg A AU - Reisshauer K AU - Waidmann R AU - Kopp H AU - Meyer P TI - [Leptospira infected rat population as probable cause of a fatal case of Weil's disease] LA - Ger MH - Animal MH - Case Report MH - English Abstract MH - Fatal Outcome MH - Human MH - Leptospira/classification/isolation & purification MH - Leptospirosis/transmission/*veterinary MH - Male MH - Mice MH - Muridae MH - Rats MH - *Rodent Diseases MH - Water Microbiology MH - Weil's Disease/diagnosis/*transmission PT - JOURNAL ARTICLE DA - 960401 DP - 1995 Nov IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 405-7 CY - GERMANY IP - 11 VI - 108 JC - 9Q8 AA - Author EM - 9606 AB - In the summer of 1992 a patient died of a leptospiral infection which he probably had contracted while he was swimming in an artificial lake in the region of Tubingen/Reutlingen. Regarding the epidemiological role of leptospirosis the rodent population was investigated, because rats and mice were often seen in the surrounding area. 11 rats and 20 mice could be trapped. From their urine or kidneys two leptospiral serovars were isolated: Serovar copenhageni from Rattus norvegicus and serovar saxkoebing from Clethrionomys glareolus. Leptospiral antibody titers were not detected in one of these infected animals. It may be supposed that the Leptospira interrogans serovar copenhageni out of the Serogroup Icterohaemorrhagiae had caused the leptospiral infection of the patient. AD - LUA Oberschleissheim. PMID- 8593131 TT - Leptospireninfizierte Rattenpopulation als wahrscheinliche Ursache eines Morbus Weil mit todlichem Verlauf. EA - A SO - Berl Munch Tierarztl Wochenschr 1995 Nov;108(11):405-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96136483 AU - Mel'nitskaia EV AU - Bernasovskaia EP AU - Kondratenko VN TI - [The development and evaluation of a leptospiral polyvalent antigenic erythrocytic diagnostic agent] LA - Rus MH - Antigens, Bacterial/*diagnostic use MH - Erythrocytes/*immunology MH - Evaluation Studies MH - Hemagglutination Tests/methods/statistics & numerical data MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Sensitivity and Specificity RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 960222 DP - 1995 Nov-Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 79-80 SB - M CY - RUSSIA IP - 6 JC - Y9O EM - 9604 PMID- 8553779 TT - Razrabotka i otsenka leptospiroznogo polivalentnogo antigennogo eritrotsitarnogo diagnostikuma. SO - Zh Mikrobiol Epidemiol Immunobiol 1995 Nov-Dec;(6):79-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 96136442 AU - Shikulov VA TI - [The systematization of leptospirosis foci] LA - Rus MH - Animal MH - Disease Reservoirs/*classification MH - Disease Vectors/classification MH - Ecology MH - Human MH - Leptospirosis/*epidemiology/transmission MH - Weil's Disease/*epidemiology/transmission PT - JOURNAL ARTICLE DA - 960222 DP - 1995 Nov-Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 26-7 SB - M CY - RUSSIA IP - 6 JC - Y9O EM - 9604 PMID- 8553734 TT - K voprosu sistematizatsii ochagov leptospiroza. SO - Zh Mikrobiol Epidemiol Immunobiol 1995 Nov-Dec;(6):26-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 96136430 AU - Sarukhanova LE AU - Volina EG AU - Levina LF TI - [A comparative study of the DNAse activity of leptospirae on solid nutrient media] LA - Rus MH - Animal MH - Cattle MH - Comparative Study MH - Culture Media MH - Deoxyribonucleases/*metabolism MH - DNA/metabolism MH - Erythrocytes MH - Leptospira/classification/*enzymology/growth & development MH - Serotyping MH - Thymus Gland RN - EC 3.1.- (Deoxyribonucleases) RN - 0 (Culture Media) RN - 9007-49-2 (DNA) PT - JOURNAL ARTICLE DA - 960222 DP - 1995 Nov-Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 11-2 SB - M CY - RUSSIA IP - 6 JC - Y9O EM - 9604 PMID- 8553717 TT - Sravnitel'noe izuchenie DNK-aznoi aktivnosti leptospir na plotnykh pitatel'nykh sredakh. SO - Zh Mikrobiol Epidemiol Immunobiol 1995 Nov-Dec;(6):11-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 96137591 AU - de Koning J AU - van der Hoeven JG AU - Meinders AE TI - Respiratory failure in leptospirosis (Weil's disease). LA - Eng MH - Adult MH - Case Report MH - Human MH - Lung/radiography MH - Male MH - Middle Age MH - Respiratory Distress Syndrome, Adult/etiology/radiography MH - Respiratory Insufficiency/*etiology/radiography MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 960213 DP - 1995 Nov IS - 0300-2977 TA - Neth J Med PG - 224-9 CY - NETHERLANDS IP - 5 VI - 47 JC - NWY AA - Author EM - 9604 AB - Two patients with leptospirosis (Weil's disease), with acute respiratory failure necessitating mechanical ventilation, are described. Adult respiratory distress syndrome (ARDS) in one patient and profuse pulmonary bleeding in the other were the respective causes of respiratory failure. One patient died after developing the multiple organ dysfunction syndrome (MODS), the other patient recovered completely. Respiratory failure is an uncommon complication of leptospirosis and is due to severe pulmonary bleeding and/or ARDS. AD - Department of General Internal Medicine, University Hospital, Leiden, Netherlands. PMID- 8544894 SO - Neth J Med 1995 Nov;47(5):224-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 96341139 AU - Candia P AU - Pinto A TI - [Leptospirosis in Gastroenterology. Study of 14 cases in the Hospital Universitario de Caracas 1984-1994] LA - Spa MH - Adult MH - Diagnosis, Differential MH - English Abstract MH - Female MH - Human MH - Jaundice/diagnosis MH - Leptospirosis/blood/cerebrospinal fluid/*diagnosis/urine MH - Male MH - Middle Age MH - Retrospective Studies MH - Venezuela PT - JOURNAL ARTICLE DA - 961205 DP - 1995 Oct-Dec IS - 0016-3503 TA - G E N PG - 273-7 CY - VENEZUELA IP - 4 VI - 49 JC - FL2 AA - Author EM - 9702 AB - 14 cases that were admitted to the Hospital Universitario de Caracas, between 1.989 and 1.994, with a definitive diagnosis of Leptospirosis by microaglutination of live antigens were studied. Most of them hospitalized at the gastroenterology service. The serovar most frequently found was icterohemorragiae 11 cases. There was a predominium for the male gender 12/2 and the majority of patients belonged to the range of age between 31 and 40. The most common forms of presentations were: fever (14), jaundice (10) and myalgias (10) while the most relevant findings at physical examination were: jaundice (12), fever (11) and hepatomegaly (8). All patients had abnormal laboratory tests and among these, aminotransferases, bilirrubin, creatinin, CPK, platelets and urinary sediment were more frequently altered. Only half of the patients were diagnosed as Leptospirosis at the moment of admission. We conclude that even though Leptospirosis is an infectious disease distributed worldwide only few cases are hospitalized and differential diagnosis is difficult because of diversity of clinical presentations and lack of laboratory resources. It is important for gastroenterologists because most of complicated cases present as jaundiced patients. AD - Servicio de Gastroenterologia Hospital Universitario de Caracas. PMID- 8762656 TT - Leptospirosis en gastroenterologia. Estudio de 14 casos en el Hospital Universitario de Caracas. 1989-1994. EA - A SO - G E N 1995 Oct-Dec;49(4):273-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 96329730 AU - Shi MH AU - Tu YR AU - Li QJ TI - [Study on geographical distribution of leptospirosis in China] LA - Chi MH - China/epidemiology MH - *Disease Outbreaks MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Morbidity MH - Support, Non-U.S. Gov't MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 960909 DP - 1995 Oct IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 259-62 CY - CHINA IP - 5 VI - 16 JC - CQG AA - Author EM - 9611 AB - Since 1955, Leptospirosis has been recognized as a notifiable infectious disease in China. According to the data gathered from 26 provinces of China (except for Taiwan) in 1955-1993, the average morbidity and mortality were 7.08/10(5) and 1.02% respectively. Distribution of the disease involved 26 provinces in China (not including Taiwan). The trend of the disease has been steady for recent years but outbreaks occasionally occurred, especially in several southern provinces of China. Potential risk factors may exist in these areas. Distribution of endemic areas of this disease is located between 25 degrees-35 degrees latitude and 100 degrees-120 degrees longitude i, e. those provinces along with drainage areas of the Yangtze River and the Huaihe River. AD - Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing. PMID- 8706089 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1995 Oct;16(5):259-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 96229861 AU - Treml F AU - Nesnalova E TI - [Leptospirosis in slaughter cattle--serologic and bacterial study] LA - Cze MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/epidemiology/*microbiology MH - Czech Republic/epidemiology MH - English Abstract MH - Leptospira/classification/immunology MH - Leptospirosis/epidemiology/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 960731 DP - 1995 Oct IS - 0375-8427 TA - Vet Med (Praha) PG - 305-9 CY - CZECH REPUBLIC IP - 10 VI - 40 JC - XBP AA - Author EM - 9610 AB - Antibodies to leptospiras were demonstrated in 91 cases (7.4%) out of 1,239 animals examined by serological assays of blood sera of cattle slaughtered in slaughter-houses and coming from 21 farms of one district. The antibodies were detected in animals coming from eleven out of the farms investigated (52.4%). The most frequent reactions were proved with leptospiras of the serovar L. grippotyphosa (61.8%) and with leptospiras of the serological group Sejroe (18.9%), rarely with leptospiras of the serovar L. icterohaemorrhagiae or copenhageni (5.7%). Antibodies to leptospiras of other serovars (L. canicola, L. bulgarica and L. hardjo) were demonstrated only as coagglutionations with the above-mentioned leptospira serovars. We failed to demonstrate leptospiras in the animals examined by culture examinations as well as by bacterioscopy. The results of examinations have shown that the cattle on Czech farms is also exposed to infections by various serovars of leptospiras. The infections are not accompanied by manifest clinical symptoms in many cases nor do they cause significant elimination of leptospiras in urine in the serologically positive animals. On the Czech cattle farms the occurrence of antibodies to leptospiras of the serovar L. grippotyphosa is prevailing; this serovar seems not to be expressly pathogenic to cattle and does not cause the formation of anthropurgic foci. Reduction in the occurrence of antibodies to leptospiras of this type is possible to achieve by preventing the contact with natural foci of this type. Hence the prognosis of epizootologic situation in bovine leptospirosis in the conditions of this country is relatively favorable. But special attention should be paid to animals bought and imported from foreign countries. These animals could be a source of some highly pathogenic serovars of leptospiras to cattle. AD - University of Veterinary Medicine and Pharmaceutical Sciences, Brno, Czech Republic. PMID- 8659079 TT - Leptospiroza jatecneho skotu--serologicke a bakteriologicke vysetreni. EA - A SO - Vet Med (Praha) 1995 Oct;40(10):305-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 96167429 AU - Hughes KL TI - The AK Sutherland oration [see comments] LA - Eng MH - Australia MH - *Awards and Prizes MH - History of Medicine, 20th Cent. MH - Leptospirosis/history MH - Publishing/history MH - Queensland MH - Societies MH - *Veterinary Medicine/history PT - BIOGRAPHY PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 960424 DP - 1995 Oct IS - 0005-0423 TA - Aust Vet J PG - 361-3 SB - M CY - AUSTRALIA IP - 10 VI - 72 JC - 9IE EM - 9606 AD - School of Veterinary Science, University of Queensland, Brisbane. CM - Comment in: Aust Vet J 1996 Mar;73(3):118 RO - M:LC2 PMID- 8599566 LR - 960909 CU - 96 PS - Sutherland AK SO - Aust Vet J 1995 Oct;72(10):361-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96072386 AU - Ahasan HA AU - Chowdhury MA AU - Azhar MA AU - Rafiqueuddin AK TI - Pitfalls in the diagnosis of jaundiced patients in the tropics [letter] LA - Eng MH - Adult MH - Bangladesh MH - Human MH - Jaundice/*etiology MH - Leptospirosis/complications MH - Liver Diseases/complications MH - Male MH - Typhoid/complications PT - LETTER DA - 960118 DP - 1995 Oct IS - 0049-4755 TA - Trop Doct PG - 191 CY - ENGLAND IP - 4 VI - 25 JC - WGC EM - 9603 PMID- 7502338 SO - Trop Doct 1995 Oct;25(4):191 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 96317775 AU - Machado ES AU - Feres JG AU - Feijo LA AU - Andrade J AU - Nogueira SA TI - Is CK-MB isoenzyme useful for diagnosis of cardiac involvement in icteric leptospirosis? LA - Eng MH - Adult MH - Creatine Kinase Isoenzymes/*blood MH - Female MH - Heart Diseases/blood/*diagnosis/*microbiology MH - Human MH - Male MH - Prospective Studies MH - Weil's Disease/*complications RN - EC 2.7.3.- (Creatine Kinase Isoenzymes) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE DA - 961203 DP - 1995 Sep-Oct IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 461-5 CY - BRAZIL IP - 5 VI - 37 JC - S9D AA - Author EM - 9702 AB - In the absence of heart failure or cardiogenic shock, cardiac involvement diagnosis in icteric leptospirosis is possible on the basis of abnormal electrocardiograms. As metabolic and electrolytic disorders are frequently seen during acute leptospirosis infection, they may be responsible for some electrocardiograms changes. We conducted a study to assess if creatine phosphokinase isoenzyme determinations are useful in selecting patients with a high cardiac involvement suspicion. Sixty- nine patients were studied prospectively. Ten patients out of 16 with cardiac involvement and 25 without had high CK-MB levels (p > 0.05), although mean values of abnormal CK-MB levels were higher in the group with cardiac involvement (p < 0.05). Our analysis indicates that serum CK-MB determination does not provide a specific indicator of myocardial involvement in the course of icteric leptospirosis. AD - Servico de Doencas Infecciosas, Universidade Federal do Rio de Janiero, Brasil. PMID- 8729758 SO - Rev Inst Med Trop Sao Paulo 1995 Sep-Oct;37(5):461-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 96147936 AU - Chen Z AU - Dai B AU - Zhang Y AU - Li S TI - [Homology study of leptospires in China with the OmpL1 gene] LA - Chi MH - Bacterial Outer Membrane Proteins/*genetics MH - DNA, Bacterial/genetics MH - English Abstract MH - *Genes, Bacterial MH - Leptospira interrogans/classification/*genetics MH - *Sequence Homology, Nucleic Acid MH - Support, Non-U.S. Gov't RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 960325 DP - 1995 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 248-51 CY - CHINA IP - 3 VI - 26 JC - GEB AA - Author EM - 9605 AB - Southern hybridization analysis with the OmpL1 gene was performed. The results of probing EcoRI-restricted genomic DNA from 18 strains in China showed that the homology fragments of OmpL1 gene were presented in 12 pathogenic Leptospira strains: sero-group Icterohaemorrhagiae (2 strains), Canicola, Ballum, Pyrogenes, Autumnalis, Australis, Pomona, Grip-potyphosa, Hebdomadis, Bataviae, and Sejroe, but they were not presented in the nonpathogenic Leptospira biflexa strain Patoc I, Leptonema illini strain 3055 and pathogenic Leptospira Serogroup Javanica, Tarassovi, Manhao and Mini. AD - Department of Pathophysiology, Sichuan University. PMID- 8586385 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1995 Sep;26(3):248-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 96147935 AU - Jiang N AU - Dai B AU - Li S AU - Zhao H AU - Liu J AU - Song S AU - Yang Y AU - Zhang Y AU - Tu Y AU - Yang H AU - et al TI - [Homology of the recombinant DNA of plasmid pDJH2 with the recombinant DNA probe of L. alstoni and analysis of its expression in Escherichia coli] LA - Chi MH - Animal MH - Antigens, Bacterial/*biosynthesis/therapeutic use MH - Bacterial Outer Membrane Proteins/genetics MH - DNA, Bacterial/*genetics MH - DNA, Recombinant/*genetics MH - English Abstract MH - Escherichia coli/metabolism MH - Gene Library MH - Leptospira/*genetics MH - Leptospira interrogans/*genetics MH - Mice MH - Mice, Inbred BALB C MH - Nucleic Acid Hybridization MH - Plasmids MH - *Sequence Homology, Nucleic Acid MH - Support, Non-U.S. Gov't MH - Weil's Disease/prevention & control RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (DNA, Bacterial) RN - 0 (DNA, Recombinant) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 960325 DP - 1995 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 241-7 CY - CHINA IP - 3 VI - 26 JC - GEB AA - Author EM - 9605 AB - Dig-labeled recombinant DNA probe of L. alstoni which contains the entire structural OmpL1 gene was hybridized with the recombinant DNA of the plasmid named pDJH2 of the gene library of L. interrogans serovar lai strain 017. The result showed a high degree of homology among them; expression of recombinant DNA of pDJH2 was achieved by beta-D- galactosidase (IPTG) induction in E. coli. The molecular weight of this product is 68kd. Then they were treated with proteinase K and subjected to SDS-PAGE. The results showed it is a protein in nature. Using the specific monoclonal antibody E4B7D5 on immunoblotting and specific polyclonal antibody on dot-ELISA assay, we investigated the immune reaction and noticed that protein 68kd might be an antigen in character. E. coli which contains the recombinant plasmid pDJH2 were injected into BALB/c mice. Then the mice were challenged by leptospires of the strong virulence strain 017, but all the infected mice survived. In this paper, we first report the expression of recombinant DNA of L. interrogans serovar lai strain 017 in E. coli when injected with IPTG, and immunoprotection of BALB/c mice which were injected with the expression against the infection of L. interrogans serovar lai strain 017. pDJH2 may be the first recombinant for which the gene has been cloned and its expression product 68kd may be the immunoprotective antigens. AD - Chengdu Institute of Biological Product, Ministry of Public Health. PMID- 8586384 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1995 Sep;26(3):241-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 95385438 AU - Teglia OF AU - Battagliotti C AU - Villavicencio RL AU - Cunha BA TI - Leptospiral pneumonia. LA - Eng MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Human MH - *Leptospira canicola MH - Leptospirosis/*diagnosis MH - Male MH - Pneumonia, Bacterial/diagnosis/*microbiology PT - JOURNAL ARTICLE DA - 951005 DP - 1995 Sep IS - 0012-3692 TA - Chest PG - 874-5 SB - A SB - M SB - X CY - UNITED STATES IP - 3 VI - 108 JC - D1C AA - Author EM - 9512 AB - Leptospirosis is an uncommon zoonosis. As a systemic infectious disease, leptospirosis usually is characterized by multisystem involvement. Pulmonary involvement with leptospirosis often is manifested by respiratory symptoms, but pneumonia commonly is not a prominent clinical manifestation of the illness. We report a case of fulminant leptospiral pneumonia in which pulmonary manifestations were primary clinical features of the illness. AD - Epidemiology and Radiology Department, Sanatorio Parque, Rosario, Argentina. PMID- 7656649 SO - Chest 1995 Sep;108(3):874-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [8 protein links] [2 nucleotide links] [211 medline neighbors] UI - 96118697 AU - Boursaux-Eude C AU - Saint Girons I AU - Zuerner R TI - IS1500, an IS3-like element from Leptospira interrogans. LA - Eng MH - Amino Acid Sequence MH - Bacterial Proteins/genetics MH - Base Sequence MH - Comparative Study MH - *DNA Insertion Elements MH - DNA Nucleotidyltransferases/genetics MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - Open Reading Frames MH - Polymerase Chain Reaction MH - Repetitive Sequences, Nucleic Acid MH - Sequence Alignment RN - EC 2.7.7.- (transposase) RN - EC 2.7.7.- (DNA Nucleotidyltransferases) RN - 0 (Bacterial Proteins) RN - 0 (DNA Insertion Elements) PT - JOURNAL ARTICLE DA - 960116 DP - 1995 Sep IS - 1350-0872 TA - Microbiology PG - 2165-73 SB - M CY - ENGLAND VI - 141 ( Pt 9) JC - BXW AA - Author EM - 9603 AB - Copies of an insertion-sequence (IS)-like element were isolated from two closely related serovars of Leptospira interrogans sensu stricto. Nucleotide sequence analysis of the 1236 bp element showed a characteristic IS structure with terminal imperfect inverted repeats (IRs) flanking a 1159 bp central region. This element was designated IS1500. Four open reading frames (orfA-orfD) were found in the central 'unique' region of IS1500. Similarities were detected between ORFA and ORFB and the putative transposases from members of the IS3 family of transposable elements. IS1500 or IS1500-like sequences were also detected in all other pathogenic leptospiral serovars, but not in the saprophytic species L. biflexa. Differences in IS1500 copy numbers in members of the same species suggest that this element can transpose. Physical mapping of IS1500 insertions in L. interrogans serovars icterohaemorrhagiae and pomona showed insertions were only on the large chromosomal replicon. The location of some IS1500 insertions coincides with regions of the genome that have undergone large rearrangements. AD - Unite de Bacteriologie Moleculaire et Medicale, Institut Pasteur, Paris, France. PMID- 7496528 SI - GENBANK/U13012 SI - GENBANK/U13013 SO - Microbiology 1995 Sep;141 ( Pt 9):2165-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [93 medline neighbors] UI - 95385651 AU - Skopp G AU - Aderjan R AU - Koster J TI - [Hair analysis in the diagnosis of toxic hepatitis after Ecstasy abuse] LA - Ger MH - Adolescence MH - Case Report MH - English Abstract MH - Enzyme Tests MH - Hair/*chemistry MH - Hepatitis, Toxic/diagnosis/*etiology MH - Human MH - Male MH - *N-Methyl-3,4-methylenedioxyamphetamine/analysis MH - Substance Abuse/*diagnosis RN - 42542-10-9 (N-Methyl-3,4-methylenedioxyamphetamine) PT - JOURNAL ARTICLE DA - 950929 DP - 1995 Aug 25 IS - 0012-0472 TA - Dtsch Med Wochenschr PG - 1165-8 SB - M SB - X CY - GERMANY IP - 34-35 VI - 120 JC - ECL AA - Author EM - 9512 AB - HISTORY AND CLINICAL FINDINGS: A young man, aged 18 years, was admitted to hospital for suspected hepatitis, having developed increasing jaundice without any pain. His urine was light brown in colour and the stools often liquid and pale. Every 14 days for the last 4 months he had been taking 2 tablets of "ecstasy" (methylenedioxyamphetamine; MDMA). Physical examination was unremarkable and the patient was in good general condition. TESTS: The activities of GOT, GPT and alkaline phosphatase were raised (to 903, 744 and 270 U/l, respectively) as was the bilirubin concentration (16.8 mg/dl). Tests were negative for: leptospira and the viruses of mumps, HI, varicella zoster, picornavirus, cytomegaly, Coxsackie and hepatitis, A, B and C. Ultrasound revealed hepatomegaly, with a normal echo pattern. Hair analysis demonstrated, in two different hair segments (0-2 cm and 2-4 cm, respectively) both MDMA (6.4 and 4.3 micrograms/g hair) and its metabolite MDA (0.7 and 5.0 micrograms/g hair). TREATMENT AND COURSE: No specific treatment was required. After intake of the drug had been stopped the transferase activities and bilirubin concentration became essentially normal. CONCLUSION: Hair analysis can be valuable in confirming "ecstasy" abuse, especially when it is denied, and thus contribute to clarifying the cause of toxic hepatitis. AD - Institut fur Rechtsmedizin, Universitat Heidelberg. PMID- 7656850 TT - Haaranalyse zur Diagnose toxischer Hepatitiden nach Missbrauch von "Ecstacy". EA - A SO - Dtsch Med Wochenschr 1995 Aug 25;120(34-35):1165-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 96048701 AU - Ciceroni L AU - D'Aniello P AU - Russo N AU - Picarella D AU - Nese D AU - Lauria F AU - Pinto A AU - Cacciapuoti B TI - Prevalence of leptospire infections in buffalo herds in Italy. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/immunology MH - Blood/microbiology MH - Buffaloes/blood/*microbiology/urine MH - Female MH - Italy/epidemiology MH - Leptospira/classification/immunology/isolation & purification MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Male MH - Prevalence MH - Seroepidemiologic Methods MH - Serotyping/veterinary MH - Urine/microbiology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 960227 DP - 1995 Aug 19 IS - 0042-4900 TA - Vet Rec PG - 192-3 SB - M CY - ENGLAND IP - 8 VI - 137 JC - XBS EM - 9605 AD - National Centre for Leptospiroses, Istituto Superiore di Sanita, Regina Elena, Rome, Italy. PMID- 8560725 SO - Vet Rec 1995 Aug 19;137(8):192-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [166 medline neighbors] UI - 96157446 AU - Oliveira MA AU - Caballero OL AU - Dias Neto E AU - Koury MC AU - Romanha AJ AU - Carvalho J AU - Hartskeerl RA AU - Simpson AJ TI - Use of nondenaturing silver-stained polyacrylamide gel analysis of polymerase chain reaction amplification products for the differential diagnosis of Leptospira interrogans infection. LA - Eng MH - Bacterial Typing Techniques MH - Base Sequence MH - Diagnosis, Differential MH - DNA, Bacterial/*analysis MH - Electrophoresis, Polyacrylamide Gel MH - Human MH - *Leptospira interrogans/classification/genetics MH - Molecular Sequence Data MH - *Polymerase Chain Reaction MH - Sensitivity and Specificity MH - Silver Staining MH - Weil's Disease/*diagnosis RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 960320 DP - 1995 Aug IS - 0732-8893 TA - Diagn Microbiol Infect Dis PG - 343-8 SB - M CY - UNITED STATES IP - 4 VI - 22 JC - DMI AA - Author EM - 9605 AB - A 285-bp DNA fragment was amplified using the polymerase chain reaction from 38 Leptospira serovars of six different genomic species. The fragments amplified exhibited differential mobilities on nondenaturing polyacrylamide gels resulting from sequence-dependent conformational alterations. Leptospira interrogans serovars could be distinguished from those of other species on this basis. AD - Centro de Pesquisas Rene Rachou, FIOCRUZ, Belo Horizonte, Minas Gerais, Brazil. PMID- 8582141 CU - 96 SI - GENBANK/S81410 SO - Diagn Microbiol Infect Dis 1995 Aug;22(4):343-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 95392692 AU - De Serres G AU - Levesque B AU - Higgins R AU - Major M AU - Laliberte D AU - Boulianne N AU - Duval B TI - Need for vaccination of sewer workers against leptospirosis and hepatitis A [see comments] LA - Eng MH - Adult MH - Age Factors MH - Antibodies, Bacterial/*blood MH - Female MH - Hepatitis A/*immunology/prevention & control MH - Hepatitis Antibodies/*blood MH - Hepatovirus/immunology MH - Human MH - Leptospira/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology/prevention & control MH - Male MH - Middle Age MH - Occupational Diseases/*immunology MH - *Sewage MH - Support, Non-U.S. Gov't MH - Vaccination RN - 0 (hepatitis A virus antibodies) RN - 0 (Antibodies, Bacterial) RN - 0 (Hepatitis Antibodies) PT - JOURNAL ARTICLE DA - 951010 DP - 1995 Aug IS - 1351-0711 TA - Occup Environ Med PG - 505-7 SB - M CY - ENGLAND IP - 8 VI - 52 JC - BWC AA - Author EM - 9512 AB - OBJECTIVES--This study compared the prevalence of Leptospira interrogans and hepatitis A virus (HAV) antibodies in serum samples from sewer workers and controls. METHODS--A blood sample was obtained from 76 of the 101 municipal sewer workers (75%) of Quebec City and from two controls matched to each for age and sex. Testing was done for antibodies against serovars of Leptospira icterohaemorragiae, bratislava, hardjo, grippotyphosa, and kennewicki (pomona) and hepatitis A. RESULTS--Sewer workers had a greater prevalence of antibodies against leptospirosis than controls (12% v 2%, P = 0.003). In contrast, antibodies to HAV were not significantly more prevalent among workers than among controls (54% v 49%, P = 0.51). Prevalence of HAV antibodies increased significantly with age both among workers and controls (chi 2 for trend, P < 0.001). In contrast with younger workers, prevalence of HAV antibodies was greater among workers > or = 40 years than among their controls (81% v 65%, P = 0.04). CONCLUSION-- Leptospirosis continues to be a problem to sewer workers but hepatitis A is apparently no longer a risk. The likely explanation is that leptospira are still abundant in the sewage system in contrast with HAV, which is only rarely to be found in sewage as a result of the generalised decrease in incidence of hepatitis A in the past three decades. The decision to vaccinate sewer workers against hepatitis A should take into account that it is impossible to avoid all contact with sewage fluid and, despite the fact that the actual incidence of hepatitis A is low, there is a real possibility of sporadic exposure during a future outbreak. AD - Centre de sante publique de Quebec, Canada. CM - Comment in: Occup Environ Med 1996 Jan;53(1):71 RO - M:LC2 PMID- 7663634 LR - 960507 SO - Occup Environ Med 1995 Aug;52(8):505-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 95363887 AU - Silva MV AU - Camargo ED AU - Batista L AU - Vaz AJ AU - Brandao AP AU - Nakamura PM AU - Negrao JM TI - Behaviour of specific IgM, IgG and IgA class antibodies in human leptospirosis during the acute phase of the disease and during convalescence. LA - Eng MH - Adolescence MH - Adult MH - Antibodies, Bacterial/immunology/*isolation & purification MH - Child MH - Comparative Study MH - Convalescence MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Follow-Up Studies MH - Human MH - IgA/*immunology/isolation & purification MH - IgG/*immunology/isolation & purification MH - IgM/*immunology/isolation & purification MH - Leptospirosis/*immunology MH - Male MH - Middle Age MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (IgA) RN - 0 (IgG) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 950914 DP - 1995 Aug IS - 0022-5304 TA - J Trop Med Hyg PG - 268-72 SB - M CY - ENGLAND IP - 4 VI - 98 JC - KAV AA - Author EM - 9511 AB - The behaviour of specific IgM, IgG and IgA class antibodies in human leptospirosis was studied by ELISA. Two groups of patients were followed up, 57 of them in the acute phase and 10 during convalescence, the latter with a mean follow-up of 10.5 months. IgM class antibodies were detected starting on the 2nd day of symptoms and were observed in 100% of patients up to the 5th month, in 66.7% up to the 7th month and in 50% up to the 12th month after the onset of symptoms. IgG class antibodies were first detected on the 7th day of symptoms in 9.1% of patients, with maximum reactivity (87.5%) between the 2nd and 3rd month, and were not detected at all in one patient. IgA class antibodies were detected starting on the 5th day of symptoms in 7.7% of patients, and in all patients on the 15th day, persisting in 100% of cases up to the 9th follow-up month. During the 12th month, they were observed in 83.3% of patients. The results indicate that an anti IgA ELISA could be of great value in seroprevalence studies on human leptospirosis. AD - Adolfo Lutz Institute, Sao Paulo, Brazil. PMID- 7636924 SO - J Trop Med Hyg 1995 Aug;98(4):268-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 95356205 AU - Brown PD AU - Gravekamp C AU - Carrington DG AU - van de Kemp H AU - Hartskeerl RA AU - Edwards CN AU - Everard CO AU - Terpstra WJ AU - Levett PN TI - Evaluation of the polymerase chain reaction for early diagnosis of leptospirosis. LA - Eng MH - Acute Disease MH - Antibodies, Bacterial/blood MH - Comparative Study MH - DNA, Bacterial/*analysis/blood/urine MH - Evaluation Studies MH - Human MH - Leptospira/*genetics/immunology/isolation & purification MH - Leptospirosis/*diagnosis MH - *Polymerase Chain Reaction MH - Reproducibility of Results MH - Support, Non-U.S. Gov't MH - Time Factors RN - 0 (Antibodies, Bacterial) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 950905 DP - 1995 Aug IS - 0022-2615 TA - J Med Microbiol PG - 110-4 SB - M CY - SCOTLAND IP - 2 VI - 43 JC - J2N AA - Author EM - 9511 AB - Early diagnosis of leptospirosis is important because severe leptospiral infection can run a fulminant course. The polymerase chain reaction (PCR) was evaluated for the detection of leptospires in clinical samples from patients with acute leptospiral infection. Blood and urine samples from 71 patients with leptospirosis were examined by PCR, culture or serology. Samples from 44 (62%) patients with the diagnosis of leptospirosis were positive by PCR as compared to 34 (48%) by culture. The presence of leptospires was demonstrated by PCR in 13 patients before the development of antibodies, as well as in two patients who were seronegative during their illness and at autopsy. Samples from 16 patients without leptospirosis were seronegative and culture negative, and also negative by PCR. We conclude that PCR is a rapid, sensitive and specific means of diagnosing leptospiral infection, especially during the first few days of the disease. AD - University of the West Indies, Faculty of Medical Sciences, Barbados. PMID- 7629850 SO - J Med Microbiol 1995 Aug;43(2):110-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 95347839 AU - Shang ES AU - Exner MM AU - Summers TA AU - Martinich C AU - Champion CI AU - Hancock RE AU - Haake DA TI - The rare outer membrane protein, OmpL1, of pathogenic Leptospira species is a heat-modifiable porin. LA - Eng MH - Bacterial Outer Membrane Proteins/*physiology MH - Base Sequence MH - Cloning, Molecular MH - DNA Primers/chemistry MH - Electric Conductivity MH - *Genes, Structural, Bacterial MH - Heat MH - Leptospira/*genetics MH - Lipid Bilayers MH - Molecular Sequence Data MH - Molecular Weight MH - Porins/*genetics MH - Recombinant Proteins MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Support, U.S. Gov't, P.H.S. RN - 0 (ompL1 protein) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (DNA Primers) RN - 0 (Lipid Bilayers) RN - 0 (Porins) RN - 0 (Recombinant Proteins) PT - JOURNAL ARTICLE ID - 2-T32-AI07323-06/AI/NIAID DA - 950825 DP - 1995 Aug IS - 0019-9567 TA - Infect Immun PG - 3174-81 SB - M SB - X CY - UNITED STATES IP - 8 VI - 63 JC - GO7 AA - Author EM - 9511 AB - The outer membranes of invasive spirochetes contain unusually small amounts of transmembrane proteins. Pathogenic Leptospira species produce a rare 31-kDa surface protein, OmpL1, which has a deduced amino acid sequence predictive of multiple transmembrane beta-strands. Studies were conducted to characterize the structure and function of this protein. Alkali, high-salt, and urea fractionation of leptospiral membranes demonstrated that OmpL1 is an integral membrane protein. The electrophoretic mobility of monomeric OmpL1 was modifiable by heat and reduction; complete denaturation of OmpL1 required prolonged boiling in sodium dodecyl sulfate (SDS), 8 M urea, and 2-mercaptoethanol. When solubilized in SDS at low temperature, a small proportion of OmpL1 exhibited an apparent molecular mass of approximately 90 kDa, indicating the existence of an SDS-unstable oligomer. OmpL1 dimers and trimers were demonstrated by nearest neighbor chemical cross-linking. In order to generate purified protein for functional studies, the ompL1 gene was ligated into the pMMB66 expression plasmid under control of the tac promoter. Although expression in Escherichia coli was toxic, most of the OmpL1 produced was found in the outer membrane, as determined by subcellular fractionation. Purified recombinant OmpL1 was reconstituted into planar lipid bilayers, demonstrating an average single channel conductance of 1.1 nS, similar to the major porin activity of native leptospiral membranes. These findings indicate that OmpL1 spans the leptospiral outer membrane and functions as a porin. AD - Department of Microbiology & Immunology, UCLA School of Medicine 90024, USA. PMID- 7622245 GS - ompL1 SO - Infect Immun 1995 Aug;63(8):3174-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 96041481 AU - Zhuo JT AU - Wang SS AU - Lan WL TI - [A discussion on setting up target age group for immunization against leptospirosis] LA - Chi MH - Adolescence MH - Adult MH - Age Factors MH - *Bacterial Vaccines MH - Child MH - Child, Preschool MH - China/epidemiology MH - Disease Outbreaks/*prevention & control MH - English Abstract MH - Female MH - Human MH - Infant MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*prevention & control MH - Male MH - *Vaccination RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 951130 DP - 1995 Aug IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 228-30 CY - CHINA IP - 4 VI - 16 JC - CQG AA - Author EM - 9602 AB - This paper presented the lesson of setting up a false immunization priority age group for leptospirosis which failed to prevent the leptospirosis outbreak. Our experience was that in the rice paddy field type endemic area the priority age group for the vaccination against leptopirosis should be 15 to 34 year olds followed by 35 years old or above. There was no preventive effect in the vaccination for the children 14 years old or yaunger, to our observation. AD - Guang-xi Autonomous Regional Hygiene and Epidemic Prevention Station, Nanning. PMID- 7585904 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1995 Aug;16(4):228-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 95347813 AU - Dobrina A AU - Nardon E AU - Vecile E AU - Cinco M AU - Patriarca P TI - Leptospira icterohemorrhagiae and leptospire peptidolgycans induce endothelial cell adhesiveness for polymorphonuclear leukocytes. LA - Eng MH - Antigens, CD18/physiology MH - Cell Adhesion MH - Cell Adhesion Molecules/metabolism/physiology MH - Cells, Cultured MH - Cycloheximide/pharmacology MH - Dactinomycin/pharmacology MH - Endothelium, Vascular/*cytology MH - Human MH - In Vitro MH - Leptospira/*immunology MH - Neutrophils/*immunology MH - Peptidoglycan/*immunology MH - Polymyxin B/pharmacology MH - Support, Non-U.S. Gov't RN - 0 (Antigens, CD18) RN - 0 (Cell Adhesion Molecules) RN - 0 (E-Selectin) RN - 0 (Peptidoglycan) RN - 1404-26-8 (Polymyxin B) RN - 50-76-0 (Dactinomycin) RN - 66-81-9 (Cycloheximide) PT - JOURNAL ARTICLE DA - 950825 DP - 1995 Aug IS - 0019-9567 TA - Infect Immun PG - 2995-9 SB - M SB - X CY - UNITED STATES IP - 8 VI - 63 JC - GO7 AA - Author EM - 9511 AB - We have examined the effect of the virulent Leptospira interrogans strain Teramo, serotype icterohemorrhagiae, on the adherence of human neutrophilic polymorphonuclear leukocytes (PMN) to cultured human umbilical vein endothelial cells (HEC). Selective pretreatment of HEC with intact or sonicated leptospires caused a dose- and time-dependent increase of HEC-PMN adhesion (13.2% +/- 2.5% adherence to untreated HEC versus 46.3% +/- 5.6% adherence to HEC pretreated for 4 h with 10(8) intact leptospires per ml [mean +/- standard error of six experiments; P < 0.001]). In contrast, selective leptospire pretreatment of PMN or the addition of leptospires during the adherence assay did not alter HEC-PMN adherence. Leptospire induction of endothelial-cell adhesiveness occurred without detectable HEC damage and was prevented by RNA and protein synthesis inhibitors and by monoclonal antibodies to the CD11/CD18 adhesion complex of neutrophils and to the endothelial- leukocyte adhesion molecule 1 (ELAM-1) of endothelial cells. Similar results were obtained with pretreatment of HEC with interleukin-1 or with the lipopolysaccharide (LPS) of the gram-negative bacterium Escherichia coli. The possibility that contamination by the LPS of gram- negative bacteria could be involved in the induction of HEC adhesiveness was ruled out by the observation that the LPS inhibitor polymyxin B, which abolished the proadhesive effect of E. coli LPS, was ineffective in inhibiting leptospire- as well as interleukin-1-induced adherence. Similarly, leptospire LPSs seemed to have no role in the increase of endothelial-cell adhesiveness, since pretreatment of HEC with a leptospire LPS extract (phenol-water method) or with a leptospire total lipid extract failed to induce the proadhesive phenotype for neutrophils. Instead, peptidoglycans extracted from our leptospires actively stimulated the endothelial proadhesive activity for neutrophils (16.5% +/- 2.1% adherence to untreated HEC versus 51.2% +/- 2.9% adherence to HEC pretreated for 4 h with 1 microgram of peptidoglycan per ml; [mean +/- standard error of four experiments; P < 0.001]). This peptidoglycan-induced activity was inhibited by monoclonal antibodies to the CD11/CD18 adhesion complex and to ELAM-1 but not by polymyxin B. We conclude that peptidoglycans from pathogenic leptospires are among the molecules that can directly activate vascular endothelial cells to increase their adhesiveness for neutrophilic granulocytes. These observations may contribute to a better understanding of the mechanisms whereby non-gram-negative bacteria modulate the local and systemic inflammatory reaction. AD - Institute of General Pathology, University of Trieste, Italy. PMID- 7542637 CU - 95 SO - Infect Immun 1995 Aug;63(8):2995-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 95357256 AU - Edwards M TI - Preventable damage. LA - Eng MH - Great Britain/epidemiology MH - Human MH - *Leptospirosis/diagnosis/epidemiology/therapy/transmission PT - JOURNAL ARTICLE DA - 950907 DP - 1995 Jul 19-25 IS - 0029-6589 TA - Nurs Times PG - 61-2 SB - N CY - ENGLAND IP - 29 VI - 91 JC - O9U EM - 9511 PMID- 7630823 LI - N SO - Nurs Times 1995 Jul 19-25;91(29):61-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 protein link] [1 nucleotide link] [151 medline neighbors] UI - 95354946 AU - Trueba GA AU - Bolin CA AU - Zuerner RL TI - Cloning of the pfaP gene of Leptospira borgpetersenii. LA - Eng MH - Amino Acid Sequence MH - Antibodies, Monoclonal MH - Bacterial Proteins/*biosynthesis/genetics MH - Base Sequence MH - Cloning, Molecular MH - Comparative Study MH - DNA Primers MH - DNA, Bacterial/genetics MH - Escherichia coli/genetics MH - Gene Library MH - *Genes, Bacterial MH - Haemophilus influenzae/genetics MH - Leptospira/*genetics/metabolism MH - Molecular Sequence Data MH - Open Reading Frames MH - Polymerase Chain Reaction MH - Recombinant Proteins/biosynthesis MH - Sequence Homology, Amino Acid RN - 0 (pfaP protein) RN - 0 (Antibodies, Monoclonal) RN - 0 (Bacterial Proteins) RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) RN - 0 (Recombinant Proteins) PT - JOURNAL ARTICLE DA - 950907 DP - 1995 Jul 4 IS - 0378-1119 TA - Gene PG - 133-4 SB - M CY - NETHERLANDS IP - 1 VI - 160 JC - FOP AA - Author EM - 9511 AB - A lambda gt11 library constructed with Leptospira borgpetersenii DNA was screened with monoclonal antibodies (mAb) recognizing a periplasmic flagella-associated protein. A plaque expressing a fusion protein (lambda F15) which reacted with the mAb was isolated and the nucleotide sequence analyzed. The deduced amino-acid (aa) sequence indicates that the pfaP gene belongs to a group of bacterial genes whose products share aa sequence and possibly functional homologies with sppA, an Escherichia coli signal peptidase-encoding gene. AD - Leptospirosis/Mycobacteriosis Research Unit, U.S. Department of Agriculture, National Animal Disease Center, Ames, IA 50010, USA. PMID- 7628708 GS - pfaP GS - sohB GS - sppA SI - GENBANK/L27482 SO - Gene 1995 Jul 4;160(1):133-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] UI - 96010546 AU - Agaev IA TI - [The anthropogenic transformation of natural foci of leptospirosis] LA - Rus MH - *Agriculture MH - Animal MH - Animals, Wild MH - Antibodies, Bacterial/blood MH - *Disease Reservoirs MH - Disease Vectors MH - English Abstract MH - Human MH - Leptospira/immunology MH - Leptospirosis/immunology/*transmission/veterinary MH - Transcaucasia MH - Trees RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 971125 DP - 1995 Jul-Aug IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 64-7 SB - M CY - RUSSIA IP - 4 JC - Y9O AA - Author EM - 9801 AB - The problems connected with epizootic consequences of the anthropogenic transformation of the landscape with respect to leptospirosis are discussed. The conclusion on changes produced by hydromelioration in the terrain, specific and etiological features of natural foci is made. Irrigation farming facilitates the formation and spread of natural foci, while drainage of a humid territory leads to the localization and suppression of such foci. PMID- 9381876 TT - Antropogennaia transformatsiia prirodnykh ochagov leptospiroza. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1995 Jul-Aug;(4):64-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 97003006 AU - Zamora J AU - Riedemann S AU - Cabezas X AU - Vega S TI - [Comparison of 4 microscopy techniques for the diagnosis of leptospirosis in wild rodents in a rural area of Valdivia, Chile] LA - Spa MH - Animal MH - Animals, Wild/microbiology MH - Chile/epidemiology MH - Comparative Study MH - *Disease Reservoirs MH - English Abstract MH - Evaluation Studies MH - Fluorescent Antibody Technique, Indirect MH - Hesperomyinae/microbiology MH - Immunoenzyme Techniques MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification/ultrastructure MH - Leptospirosis/diagnosis/epidemiology/*veterinary MH - Mice/microbiology MH - Microscopy/*methods MH - Microscopy, Fluorescence MH - Muridae/*microbiology MH - Rats/microbiology MH - Rodent Diseases/*diagnosis/epidemiology/microbiology MH - Rural Health MH - Silver Staining MH - Species Specificity MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 961210 DP - 1995 Jul-Sep IS - 0187-4640 TA - Rev Latinoam Microbiol PG - 267-72 CY - MEXICO IP - 3 VI - 37 JC - SEP AA - Author EM - 9702 AB - Kidneys of six different species of 93 wild rodents captured in the rural area of Valdivia (Chile) were simultaneously examined for leptospira infection by means of Levaditi silver stain, dark ground microscopy in wet smears, and immunofluorescence and immunoperoxidase techniques using pooled antiserum against hardjo and pomona serovars. Leptospira was shown to be present in 40 (43.0%) rodents. They were detected in five of the six species: Akodon olivaceus, Akodon longipilis, Rattus rattus, Oryzomis longicaudatus and Mus musculus. Levaditi's technique detected the highest number of positive samples (67.5%) and the dark field microscopy the lowest (32.5%). The detection of leptospira in the kidneys of these wild rodents suggests that their urine may play an important role in the dissemination of leptospirosis in this area of Valdivia. AD - Instituto de Microbiologia, Universidad Austral de Chile, Valdivia. PMID- 8850345 TT - Comparacion de cuatro tecnicas microscopicas para el diagnostico de leptospirosis en roedores silvestres en el area rural de Valdivia, Chile. EA - A SO - Rev Latinoam Microbiol 1995 Jul-Sep;37(3):267-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [79 medline neighbors] UI - 96287937 AU - Muthusethupathi MA AU - Shivakumar S AU - Suguna R AU - Jayakumar M AU - Vijayakumar R AU - Everard CO AU - Carrington DG TI - Leptospirosis in Madras--a clinical and serological study. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Antibodies, Bacterial/blood MH - Conjunctival Diseases/physiopathology MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Fever/physiopathology MH - Hemodialysis MH - Human MH - IgG/blood MH - IgM/blood MH - India/epidemiology MH - Jaundice/physiopathology MH - Kidney Failure, Acute/physiopathology/therapy MH - Leptospira/classification/isolation & purification MH - Leptospirosis/*epidemiology/immunology/physiopathology MH - Male MH - Middle Age MH - Muscular Diseases/physiopathology MH - Peritoneal Dialysis MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (IgG) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 961003 DP - 1995 Jul IS - 0004-5772 TA - J Assoc Physicians India PG - 456-8 CY - INDIA IP - 7 VI - 43 JC - HG7 AA - Author EM - 9612 AB - Leptospirosis was confirmed by Microscopic Agglutination Test (MAT) and/or ELISA in 57 patients admitted to the Government General Hospital, Madras, India, during November and December of 1990 and 1991 with symptomatology suggestive of the disease. Fifty (88%) of the 57 cases were males; the mean age of all the cases was 39.6 years (range 17-72). The main clinical features were: fever 100% jaundice 84%, Myalgia 82%, acute renal failure 72% and conjunctival suffusion 58%. Non-azotemic jaundice occurred in 19% of cases. Renal failure was non- oliguric in 24% of cases. 3.5% of patients died. 23 patients underwent peritoneal and/or hemodialysis. ELISA IgM titres ranged from 1:80 to 1:10240 (geometric mean tire 911). MAT titres > or = 1:1600 and > or = 1:800 occurred in 39 of 54 and 51 of 54 cases respectively. Autumnalis was the serogroup most commonly recorded serologically, and Leptospira interrogans serovar autumnalis was isolated from one patient. This study shows that leptospirosis is a significant health problem in Madras, though normally grossly underestimated due to the absence of routine laboratory diagnostic facilities for the disease. Gross under- reporting is also likely in other high rainfall third world areas. AD - Dept of Nephrology, Madras Medical College, India. PMID- 8713215 SO - J Assoc Physicians India 1995 Jul;43(7):456-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 96205206 AU - Trnjak Z AU - Dokic M AU - Marinkovic V AU - Lako B AU - Begovic V AU - Milosevic N AU - Milanovic M AU - Kupresanin S TI - [A severe form of leptospirosis] LA - Scr MH - Case Report MH - Human MH - Male MH - Middle Age MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 960625 DP - 1995 Jul-Aug IS - 0042-8450 TA - Vojnosanit Pregl PG - 411-5 CY - YUGOSLAVIA IP - 4 VI - 52 JC - XHM EM - 9608 AD - Vojnomedicinska akademija, Institut za mikrobiologiju ZPM, Beograd. PMID- 8629379 TT - Teska forma leptospiroze. SO - Vojnosanit Pregl 1995 Jul-Aug;52(4):411-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 96131135 AU - Feresu SB AU - Bolin CA AU - Korver H AU - Van de Kemp H TI - Identification of leptospires of the Pomona and Grippotyphosa serogroups isolated from cattle in Zimbabwe. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Monoclonal MH - Cattle MH - Cattle Diseases/*microbiology MH - Kidney/microbiology MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Male MH - Polymerase Chain Reaction/veterinary MH - Polymorphism, Restriction Fragment Length MH - Serotyping MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Zimbabwe RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE ID - 1 F05 TW 4154-01/TW/FIC DA - 960125 DP - 1995 Jul IS - 0034-5288 TA - Res Vet Sci PG - 92-4 SB - M CY - ENGLAND IP - 1 VI - 59 JC - R7D AA - Author EM - 9603 AB - Two strains of the genus Leptospira, isolated from kidneys of oxen slaughtered in Zimbabwe, one belonging to serogroup Pomona (strain SBF 8) and the other to serogroup Grippotyphosa (strain SBF 32), were identified by using cross-agglutinin absorption, monoclonal antibody, restriction fragment length polymorphism and polymerase chain reaction analyses. The identification of the two strains was equivocal. Strain SBF 8 showed a close similarity to both serovars mozdok and proechimys by cross-agglutinin absorption tests and to serovar pomona by monoclonal antibody analysis, but had a distinct DNA restriction pattern. Strain SBF 32 showed a close antigenic similarity to serovars ratnapura, grippotyphosa and valbuzzi by the cross-agglutinin absorption test, and to serovar ratnapura by monoclonal antibody analysis but also had a distinct DNA restriction pattern. Both strains SBF 8 and SBF 32 reacted as members of species Leptospira kirschneri by the polymerase chain reaction. It is concluded that strains SBF 8 and SBF 32 represent new genetic strains in the Pomona and Grippotyphosa groups, respectively. AD - Department of Biological Sciences, University of Zimbabwe, Harare. PMID- 8525094 SO - Res Vet Sci 1995 Jul;59(1):92-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 95318544 AU - Merien F AU - Baranton G AU - Perolat P TI - Comparison of polymerase chain reaction with microagglutination test and culture for diagnosis of leptospirosis. LA - Eng MH - Agglutination Tests/*methods MH - Bacteriological Techniques MH - Base Sequence MH - Comparative Study MH - DNA Primers MH - DNA, Bacterial/blood/cerebrospinal fluid/urine MH - Genes, Bacterial MH - Human MH - Leptospira/genetics/*isolation & purification MH - Leptospirosis/blood/*diagnosis/physiopathology MH - Molecular Sequence Data MH - Polymerase Chain Reaction/*methods MH - Sensitivity and Specificity MH - Support, Non-U.S. Gov't RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 950801 DP - 1995 Jul IS - 0022-1899 TA - J Infect Dis PG - 281-5 SB - A SB - M CY - UNITED STATES IP - 1 VI - 172 JC - IH3 AA - Author EM - 9510 AB - Polymerase chain reaction assay (PCR) amplifying a fragment of the Leptospira rrs gene was compared with culture and microagglutination test (MAT) for the diagnosis of leptospirosis in a study of 200 patients with various clinical syndromes compatible with leptospirosis. For the first group of samples tested, PCR identified the 14 cases that later were unequivocally confirmed to be leptospirosis. Thirteen other systemic cases presenting decreasing leptospiral antibody titers were also detected by PCR. The average persistence of leptospiral DNA in serum was estimated at 12 days, with a maximum of 56 days in a culture- confirmed case. The possibility of detecting leptospires in aqueous humor during the ocular complications of the disease was confirmed. The results suggest that PCR is an efficient tool for early diagnosis of leptospirosis during the first 10 days of the disease, especially when the clinical expression of the disease is confusing. AD - Laboratoire des Leptospires, Institut Pasteur, Noumea, New Caledonia. PMID- 7797932 GS - rrs SO - J Infect Dis 1995 Jul;172(1):281-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 95397028 AU - Suarez Hernandez M AU - Santisteban Mota R AU - Cabrera Cabrera J AU - del Risco Alard AU - Pelaez Martinez R TI - [A clinico-epidemiological study of leptospirosis in adults in the province of Ciego de Avila] LA - Spa MH - Adolescence MH - Adult MH - Age Distribution MH - Cuba/epidemiology MH - English Abstract MH - Human MH - Incidence MH - Leptospira/classification MH - Leptospirosis/diagnosis/*epidemiology/microbiology MH - Seasons MH - Serotyping PT - JOURNAL ARTICLE DA - 951011 DP - 1995 Jul IS - 0014-2565 TA - Rev Clin Esp PG - 459-62 CY - SPAIN IP - 7 VI - 195 JC - RNL AA - Author EM - 9512 AB - A clinical epidemiological study of reported leptospirosis cases in adults in the period 1984-1988 in the province Ciego de Avila, Republic of Cuba, was conducted. The most frequent symptoms and signs were: fever, headache and arthralgia. Eighty-two percent of patient were anicteric. The most frequent presumptive diagnosis included leptospirosis, virosis, and febrile syndrome. Sporadic cases predominated over cluster cases. The incidence of cases was higher from October to December. Sixty-five percent of patients were 36 years old or less. The serogroups detected more frequently were Leptospira interrogans var. Australia and Leptospira interrogans var Pomona. The high range of diagnostic and presumptive approaches with cases show that most cases would go undetected if an active surveillance is not implemented. AD - Hospital Provincial Docente Dr. Antonio Luaces Iraola, Ciego de Avilo, Cuba. PMID- 7667520 TT - Estudio clinico-epidemiologico de la leptospirosis en adultos, en la provincia de Ciego de Avila. EA - A SO - Rev Clin Esp 1995 Jul;195(7):459-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 96082433 AU - Levesque B AU - De Serres G AU - Higgins R AU - D'Halewyn MA AU - Artsob H AU - Grondin J AU - Major M AU - Garvie M AU - Duval B TI - Seroepidemiologic study of three zoonoses (leptospirosis, Q fever, and tularemia) among trappers in Quebec, Canada. LA - Eng MH - Adult MH - Antibodies, Bacterial/blood MH - Coxiella burnetii/immunology MH - Female MH - Francisella tularensis/immunology MH - Human MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Occupational Diseases/*epidemiology/immunology MH - Q Fever/*epidemiology/immunology MH - Quebec/epidemiology MH - Tularemia/*epidemiology/immunology MH - *Zoonoses RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 951212 DP - 1995 Jul IS - 1071-412X TA - Clin Diagn Lab Immunol PG - 496-8 SB - M CY - UNITED STATES IP - 4 VI - 2 JC - CB7 AA - Author EM - 9602 AB - This study was undertaken to evaluate the prevalence of antibodies against Francisella tularensis, Coxiella burnetii, and certain serovars of Leptospira interrogans among trappers in Quebec, Canada. Muskrat trapping was identified as a risk factor for F. tularensis infection, whereas having a cat at home apparently protected trappers against infection by L. interrogans. High percentages of control sera were positive for antibodies against C. burnetii (15%) and L. interrogans (5%), most frequently serovar bratislava. This is the first report of human infection by serovar bratislava in North America. AD - Centre de Sante publique de Quebec, Ste-Foy, Canada. PMID- 7583933 SO - Clin Diagn Lab Immunol 1995 Jul;2(4):496-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 96065607 AU - Farr RW TI - Leptospirosis. LA - Eng MH - Animal MH - Antibiotics/therapeutic use MH - Human MH - Leptospira interrogans/physiology MH - Leptospirosis/diagnosis/drug therapy/*etiology/prevention & control MH - Zoonoses RN - 0 (Antibiotics) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 951130 DP - 1995 Jul IS - 1058-4838 TA - Clin Infect Dis PG - 1-6; quiz 7-8 SB - M CY - UNITED STATES IP - 1 VI - 21 JC - A4J EM - 9602 AD - Department of Medicine, Robert C. Byrd Health Sciences Center of West Virginia University, Morgantown 26506, USA. RF - 35 PMID- 7578715 SO - Clin Infect Dis 1995 Jul;21(1):1-6; quiz 7-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 96014721 AU - Ciceroni L AU - Bartoloni A AU - Pinto A AU - Guglielmetti P AU - Barahona HG AU - Roselli M AU - Paradisi F TI - Prevalence of leptospiral infections in humans in Cordillera Province, Bolivia. LA - Eng MH - Adolescence MH - Adult MH - Age Distribution MH - Aged MH - Bolivia/epidemiology MH - Child MH - Child, Preschool MH - Female MH - Human MH - Infant MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Prevalence MH - Serodiagnosis MH - Sex Distribution PT - JOURNAL ARTICLE DA - 951103 DP - 1995 Jul-Aug IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 385-6 SB - M CY - ENGLAND IP - 4 VI - 89 JC - WBU EM - 9601 AD - Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, Rome, Italy. PMID- 7570871 SO - Trans R Soc Trop Med Hyg 1995 Jul-Aug;89(4):385-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96047605 AU - Scanziani E AU - Crippa L AU - Giusti AM AU - Luini M AU - Pacciarini ML AU - Tagliabue S AU - Cavalletti E TI - Leptospira interrogans serovar sejroe infection in a group of laboratory dogs. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals, Laboratory MH - Antibodies, Bacterial/blood MH - Blotting, Southern MH - Chronic Disease MH - Dog Diseases/*microbiology/pathology MH - Dogs MH - Female MH - Kidney/microbiology/pathology MH - Leptospira interrogans/genetics/immunology/*isolation & purification MH - Leptospirosis/immunology/microbiology/pathology/*veterinary MH - Male MH - Nephritis, Interstitial/microbiology/pathology/*veterinary MH - Serotyping RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 951114 DP - 1995 Jul IS - 0023-6772 TA - Lab Anim PG - 300-6 SB - M CY - ENGLAND IP - 3 VI - 29 JC - KYQ AA - Author EM - 9601 AB - Interstitial nephritis was seen histologically in 19 (59%) out of 32 pure-breed beagle dogs (16 males and 16 females) subjected to standard safety tests. In these animals no clinical abnormalities were observed and all the tested parameters (haematology, biochemistry and urine analysis) were within the normal ranges. Leptospiral antibody titres ranging from 1 : 100 to 1 : 6400, against a serovar (hardjo) belonging to the Sejroe serogroup, were detected by the microscopic agglutination test (MAT) in the serum of the 19 dogs with interstitial nephritis. All animals without renal lesions were seronegative. Leptospiral antigen was detected immunohistochemically in the kidneys of 4 dogs; leptospires were detected in Warthin-Starry stained sections of one dog. Leptospires were isolated from the kidneys of 3 of the 4 dogs examined by bacterial culture. The isolated strains were typed as serovar sejroe by restriction endonuclease digestion and Southern blot hybridization analysis of their DNA. It was concluded that Leptospira interrogans serovar sejroe, was responsible for an asymptomatic chronic renal infection which was widespread in this group of laboratory dogs. AD - Istituto di Anatomia Patologica Veterinaria e Patologia Aviare, Facolta di Medicina Veterinaria, Milan, Italy. PMID- 7564215 SO - Lab Anim 1995 Jul;29(3):300-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [96 medline neighbors] UI - 96007053 AU - Sehgal SC AU - Murhekar MV AU - Sugunan AP TI - Outbreak of leptospirosis with pulmonary involvement in north Andaman. LA - Eng MH - *Disease Outbreaks MH - Human MH - India/epidemiology MH - Lung Diseases/*etiology MH - Weil's Disease/complications/*epidemiology PT - JOURNAL ARTICLE DA - 951024 DP - 1995 Jul IS - 0971-5916 TA - Indian J Med Res PG - 9-12 CY - INDIA VI - 102 JC - GJF AA - Author EM - 9601 AB - An outbreak of acute febrile illness with haemorrhagic manifestations and pulmonary involvement occurred in Diglipur of North Andaman during October-November 1993. Investigations were carried out to see whether leptospires were responsible for this outbreak. Serum samples were collected from suspected cases and tested for presence of antibodies to leptospires by microscopic agglutination test (MAT) using a battery of 19 antigens representing 16 serogroups. 66.7 per cent of the specimens showed significant titres of antibodies against leptospires, 18 of 23 paired sera (78.3%) showed sero-conversion or four-fold rise in antibody titres. The commonest serovar involved was Leptospira grippotyphosa followed by L. canicola and L. JEZ bratislava. In 7 patients L. grippotyphosa was the sole serovar against which antibodies were detected. Clinical and epidemiological observations of this outbreak were similar with that of earlier seasonal outbreaks of acute febrile illness with haemorrhagic manifestations occurring in the same area, indicating that the past outbreaks may also have been due to leptospires. This is the first report of pulmonary leptospirosis from India. AD - Regional Medical Research Centre (ICMR), Port Blair, Andaman Island. PMID- 7558211 SO - Indian J Med Res 1995 Jul;102:9-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 96083192 AU - da Silva JJ AU - Netto BA AU - Lilembaum W AU - Alvim ME AU - de Oliveira AV TI - The hemorrhagic syndrome of leptospirosis: an experimental study in guinea pigs. LA - Eng MH - Animal MH - Guinea Pigs MH - Hemorrhage/*microbiology MH - *Leptospirosis MH - Syndrome PT - JOURNAL ARTICLE DA - 951212 DP - 1995 Jul-Sep IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 169-77 CY - BRAZIL IP - 3 VI - 28 JC - RET AA - Author EM - 9602 AB - The hemorrhagic syndrome of leptospirosis was studied in guinea pigs. The study correlates hematological, histopathological and immunohistochemical alterations in sixty animals inoculated by the intraperitoneal route with 1ml of the culture of virulent strain of Leptospira interrogans serovar copenhageni. Leptospirae antigens were detected by immunoperoxidase, chiefly in liver, kidney and heart muscle capillaries. Possible pathogenic mechanisms responsible for hemorrhagic syndrome are discussed with emphasis on toxic and anoxic attacks causing damage to endothelia, platelet depletion and alterations to hemostasia rates: prothrombin time [PT], partial thromboplastin time [PTT] and fibrinogen concentrations. The clinical-laboratory picture is compatible with the histopathological observation of disseminated intravascular coagulation [DIC] in most of the guinea pigs from day 4 of infection. AD - Laboratorio de Pesquisa em Anatomia Patologica, Hospital Evandro Chagas do Instituto Oswaldo Cruz da Fundacao Oswaldo Cruz, Rio de Janeiro, Brasil. PMID- 7480909 SO - Rev Soc Bras Med Trop 1995 Jul-Sep;28(3):169-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 95383123 TI - Veterinary public health. Leptospirosis. LA - Eng LA - Fre MH - Adolescence MH - Adult MH - Albania/epidemiology MH - Animal MH - Cattle MH - Disease Reservoirs MH - Female MH - Human MH - Leptospirosis/*epidemiology/prevention & control MH - Male MH - Rats MH - *Rural Health MH - Water Microbiology PT - JOURNAL ARTICLE DA - 951003 DP - 1995 Jun 16 IS - 0049-8114 TA - Wkly Epidemiol Rec PG - 173-5 CY - SWITZERLAND IP - 24 VI - 70 JC - AVX EM - 9512 PMID- 7654524 NI - A SO - Wkly Epidemiol Rec 1995 Jun 16;70(24):173-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 96022509 AU - Everard CO AU - Edwards CN AU - Everard JD AU - Carrington DG TI - A twelve-year study of leptospirosis on Barbados. LA - Eng MH - Adolescence MH - Adult MH - Age Distribution MH - Aged MH - Aged, 80 and over MH - Barbados/epidemiology MH - Child MH - Child, Preschool MH - Female MH - Human MH - Infant MH - Leptospirosis/*epidemiology/mortality MH - Male MH - Middle Age MH - Sex Distribution MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 960111 DP - 1995 Jun IS - 0392-2990 TA - Eur J Epidemiol PG - 311-20 SB - M CY - NETHERLANDS IP - 3 VI - 11 JC - ERE AA - Author EM - 9603 AB - Between November 1979 and December 1991, 398 cases of severe leptospirosis were confirmed on Barbados (range for 1980-1991 23-56; mean 32.7; incidence 13.3/100,000/year). For the six-year periods 1980- 1985 and 1986-1991 there was no significant change in incidence with time. Incidence is unlikely to change significantly in the next decade. Monthly average case numbers ranged from 1.4 (July) to 4.3 (November). The average (2.8) for June to December (the 7 wetter months) was not significantly higher than that (2.5) for January to May (the 5 drier months). The age range was 7-86. There were three times as many male cases (302) as female (96), and nearly 10 times as many in those < 35. Although the highest number of cases (69) was in males aged 15-24, the highest incidence was in the older age groups, particularly the male 65- 74 year-olds, and the female 55-64 year-olds. Leptospirosis was the proven cause of death in 55 (13.8%) hospital patients (annual range 0- 13, mean 4.5). Some of a further 39 fatalities might have been cases. Death from leptospirosis was nearly twice as common among the women as among the men. Only one patient under 20 years of age died. Leptospira were isolated and identified from 117 (29.4%) of the 398 sick patients. The infecting organisms were bim (serogroup Autumnalis--75), copenhageni (Icterohaemorrhagiae-26), arborea (Ballum-14) and bajan (Australis-2). These infecting serovars could not be distinguished clinically, but infection was milder in children than in adults. Despite its predominance in surveyed children, serogroup Panama was virtually absent in this study. Rainfall is the major factor affecting the distribution of cases; not surprisingly, sanitation workers and agricultural workers appear to be the groups at highest risk. The general lack of clear-cut risk factors reflects the ubiquity of leptospires in the environment and the fact that the disease is not entirely occupational. AD - Leptospira Laboratory, St. Michael, Barbados. PMID- 7493664 SO - Eur J Epidemiol 1995 Jun;11(3):311-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 96137338 AU - Gavaldon DG AU - Cisneros MA AU - Rojas N AU - Moles-Cervantes LP TI - [Significance of human leptospirosis in Mexico. Detection of Leptospira antibodies in a blood donor population] LA - Spa MH - Adolescence MH - Adult MH - Aged MH - Antibodies, Bacterial/*blood MH - *Blood Donors MH - English Abstract MH - Female MH - Human MH - Leptospira/*immunology MH - Leptospirosis/blood/*epidemiology MH - Male MH - Mexico MH - Middle Age MH - Seroepidemiologic Methods MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 960320 DP - 1995 May-Jun IS - 0016-3813 TA - Gac Med Mex PG - 289-92 CY - MEXICO IP - 3 VI - 131 JC - FFF AA - Author EM - 9605 AB - The presence of specific serum antibodies has been used as a diagnostic test for human leptospirosis. The presence of these antibodies in humans is indicative of an active natural infection. Its detection after exposure denotes the presence of immunity. Serum samples from 206 adult blood donors were analyzed with a microscopic agglutination assay against 7 serovars of Leptospira interrogans. A total of 7% were positive with the following serovar distribution; shermani 53%, canicola 33%, pyrogens 20%, pomona 13% and icterohaemorrhagiae 6%. The highest frequency of seropositivity was found in the 20 year to 39 age group. These results in asymptomatic individuals show that leptospirosis is a frequent zoonosis in Mexico. AD - Universidad Autonoma Metropolitana-Xochimilco, Departamentos de Atencion a la Salud y Produccion Agricola y Animal, Coyoacan, Mexico D.F. PMID- 8582567 TT - La importancia de la leptospirosis humana en Mexico. Deteccion de anticuerpos antileptospira en una poblacion de donadores de sangre. EA - A SO - Gac Med Mex 1995 May-Jun;131(3):289-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 95271636 AU - Gerritsen MA AU - Smits MA AU - Olyhoek T TI - Random amplified polymorphic DNA fingerprinting for rapid identification of leptospiras of serogroup Sejroe. LA - Eng MH - Animal MH - Base Sequence MH - Cattle MH - DNA Fingerprinting MH - DNA Primers/chemistry MH - DNA, Bacterial/*analysis/chemistry MH - Leptospira/genetics/*isolation & purification MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - *Polymorphism (Genetics) MH - Sheep MH - Support, Non-U.S. Gov't RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 950622 DP - 1995 May IS - 0022-2615 TA - J Med Microbiol PG - 336-9 SB - M CY - SCOTLAND IP - 5 VI - 42 JC - J2N AA - Author EM - 9508 AB - Eight leptospiral and three non-leptospiral primers were examined in the development of a random amplified polymorphic DNA (RAPD) fingerprinting method for identification of leptospiral serovars within the serogroup Sejroe. The strains examined comprised 19 reference strains of serogroup Sejroe, five field strains and 17 Leptospira borgpetersenii serovar hardjo type hardjobovis strains. Unique DNA banding patterns were obtained for each of the 17 reference strains with L. hardjo type hardjobovis-derived primers, and all clinical isolates were identified as L. hardjo type hardjobovis. Although the profiles were specific for each serovar, most serovars within serogroup Sejroe clustered into previously recognised genetic groups. RAPD fingerprinting is a simple, rapid method suitable for the identification of some Leptospira serovars. AD - Department of Bacteriology, Central Veterinary Institute, Lelystad, The Netherlands. PMID- 7752212 SO - J Med Microbiol 1995 May;42(5):336-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [2 protein links] [1 nucleotide link] [170 medline neighbors] UI - 95270622 AU - Afseth G AU - Mo YY AU - Mallavia LP TI - Characterization of the 23S and 5S rRNA genes of Coxiella burnetii and identification of an intervening sequence within the 23S rRNA gene. LA - Eng MH - Amino Acid Sequence MH - Base Sequence MH - Coxiella burnetii/*genetics MH - DNA, Ribosomal/genetics MH - Genes, Bacterial/*genetics MH - Introns/*genetics MH - Molecular Sequence Data MH - RNA, Ribosomal, 23S/*genetics MH - RNA, Ribosomal, 5S/*genetics MH - Sequence Analysis, DNA MH - Support, U.S. Gov't, P.H.S. RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Ribosomal, 23S) RN - 0 (RNA, Ribosomal, 5S) PT - JOURNAL ARTICLE ID - AI20190/AI/NIAID DA - 950620 DP - 1995 May IS - 0021-9193 TA - J Bacteriol PG - 2946-9 SB - M CY - UNITED STATES IP - 10 VI - 177 JC - HH3 AA - Author EM - 9508 AB - Characterization of the rRNA operon from the obligate intracellular bacterium Coxiella burnetii has determined the order of the rRNA genes to be 16S-23S-5S. A 444-bp intervening sequence (IVS) was identified to interrupt the 23S rRNA gene beginning at position 1176. The IVS is predicted to form a stem-loop structure formed by flanking inverted repeats, and the absence of intact 23S rRNA molecules suggests that the loop is removed. An open reading frame in the IVS has been identified that shows 70% similarity at the amino acid level to IVS open reading frames characterized from four species of Leptospira. AD - Department of Microbiology, Washington State University, Pullman 99164- 4233, USA. PMID- 7751314 SI - GENBANK/X79704 SO - J Bacteriol 1995 May;177(10):2946-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 95400903 AU - Younes-Ibrahim M AU - Burth P AU - Faria MV AU - Buffin-Meyer B AU - Marsy S AU - Barlet-Bas C AU - Cheval L AU - Doucet A TI - Inhibition of Na,K-ATPase by an endotoxin extracted from Leptospira interrogans: a possible mechanism for the physiopathology of leptospirosis. LA - Eng MH - Animal MH - Dose-Response Relationship, Drug MH - Endotoxins/administration & dosage/*pharmacology MH - Epithelium/enzymology MH - Kidney/cytology MH - Kidney Medulla/enzymology MH - *Leptospira interrogans MH - Leptospirosis/*physiopathology MH - Na(+)-K(+)-Exchanging ATPase/*antagonists & inhibitors/pharmacokinetics MH - Rabbits MH - Support, Non-U.S. Gov't RN - EC 3.6.1.37 (Na(+)-K(+)-Exchanging ATPase) RN - 0 (Endotoxins) PT - JOURNAL ARTICLE DA - 951017 DP - 1995 May IS - 0764-4469 TA - C R Acad Sci III PG - 619-25 SB - M CY - FRANCE IP - 5 VI - 318 JC - CA1 AA - Author EM - 9512 AB - Clinical manifestations of leptospirosis include disorders of the electrolytical balance which might be related to inhibition of Na,K- ATPase. Although the physiopathological cellular mechanism of leptospirosis remains unknown, a bacterial endotoxin has been incriminated. Therefore, we evaluated whether a glycolipoprotein fraction extracted from Leptospira interrogans and known to be cytotoxic might inhibit Na,K-ATPase. This glycolipoprotein fraction (GLP) inhibited Na,K-ATPase activity in rabbit kidney epithelial cells as well as Na,K-ATPase purified from rabbit kidney medulla. Inhibition was dose-dependent, and at maximum it almost abolished Na,K-ATPase activity whereas it had no effect on other enzymes. The GLP did not change the apparent affinity of Na,K-ATPase for potassium whereas it increased that for sodium, revealing a mechanism of inhibition different from that of ouabain. Finally, the inhibitory principle present in the GLP preparation was thermostable and was curtailed by the presence of albumin. In conclusion, a glycolipoproteic fraction extracted from Leptospira interrogans contains a specific inhibitor of Na,K-ATPase. This glycolipoproteic fraction which is present in diseased tissues might induce, through this inhibitor, cellular dysfunctions responsible for the symptoms, in particular those associated with electrolytical disorders such as disturbances of renal electrolyte handling, cardiac arrhythmia or diarrhoea. AD - Laboratoire de physiologie cellulaire, College de France, Paris. PMID- 7671008 SO - C R Acad Sci III 1995 May;318(5):619-25 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 95345334 AU - Watt G AU - Warrell DA TI - Leptospirosis and the Jarisch-Herxheimer reaction [letter; comment] LA - Eng MH - Antibiotics/*therapeutic use MH - Human MH - Leptospirosis/*drug therapy/immunology RN - 0 (Antibiotics) PT - COMMENT PT - LETTER DA - 950831 DP - 1995 May IS - 1058-4838 TA - Clin Infect Dis PG - 1437-8 SB - M CY - UNITED STATES IP - 5 VI - 20 JC - A4J EM - 9511 CM - Comment on: Clin Infect Dis 1994 Jun;18(6):1004-6 RO - M:LC2 PMID- 7620046 LR - 951016 SO - Clin Infect Dis 1995 May;20(5):1437-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [50 medline neighbors] UI - 95249954 AU - Inada R AU - Ido Y AU - Kaneko R AU - Hoki R AU - Ito H AU - Wani H AU - Okuda K TI - [Scientific raisins from 125 years SMW (Swiss Medical Weekly). A brief report on the discovery of the pathogen (Spirochaeta icterohaemorrhagiae nov. sp.) of so-called Weil's disease in Japan and on current studies of the disease. 1916 (classical article)] LA - Ger MH - History of Medicine, 20th Cent. MH - Human MH - *Leptospira interrogans MH - Weil's Disease/*history PT - CLASSICAL ARTICLE PT - HISTORICAL ARTICLE PT - BIOGRAPHY PT - JOURNAL ARTICLE DA - 950601 DP - 1995 Apr 22 IS - 0036-7672 TA - Schweiz Med Wochenschr PG - 816-26 SB - M CY - SWITZERLAND IP - 16 VI - 125 JC - UEI EM - 9508 PMID- 7732354 CU - 96 TT - Eine kurze Mitteilung uber die Entdeckung des Erregers (Spirochaeta ictero-haemorrhagiae nov. sp.) der sogenannten Weil'schen Krankheit in Japan und uber die neueren Untersuchungen uber die Krankheit. SO - Schweiz Med Wochenschr 1995 Apr 22;125(16):816-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 97078172 AU - Chandrasekaran S AU - Mallika M AU - Pankajalakshmi VV TI - Studies on the incidence of leptospirosis and possible transmission of Leptospira during leptospiraemia. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Child MH - Child, Preschool MH - Female MH - Human MH - India/epidemiology MH - Infant MH - Leptospirosis/diagnosis/*epidemiology/transmission MH - Male MH - Middle Age MH - Parasitemia/diagnosis/transmission PT - JOURNAL ARTICLE DA - 970512 DP - 1995 Apr IS - 0377-4929 TA - Indian J Pathol Microbiol PG - 133-7 CY - INDIA IP - 2 VI - 38 JC - GKK AA - Author EM - 9707 AB - During the year 1991 and in the first half year of 1992 a total of 179 cases and 288 cases respectively were tested for the presence of Leptospira by dark ground microscopy and 86 cases (48%) and 157 cases (54.5%) were found to be positive for Leptospira in their blood samples only. The disease was endemic and more prevalent in the age group of 5 to 14 years and 15 to 54 years and affected both sexes. Clinical categorisation of 169 cases in 1991 and 266 cases in the first half of the year 1992 along with the dark ground microscopy results showed that there was no strict correlation between the concentration of Leptospira in the blood and the severity of infection. Epidemiological data regarding the occupation and the contacts indicated that students and medical staff accounted for more than fifty percent of leptospiral infection and there was the possibility of transmission of Leptospira during leptospiraemia. Dark ground microscopy studies on blood samples from 20 cases who came for repeat testing showed the presence of Leptospira in blood up to 43 days and suggested that the convalescent carrier may have a role in the transmission of Leptospira during Leptospiraemia. AD - Institute of Microbiology, Madurai Medical College. PMID- 8919096 SO - Indian J Pathol Microbiol 1995 Apr;38(2):133-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 96164788 AU - Lilenbaum W AU - Dos Santos MR TI - [Leptospirosis in animal reproduction: III. Role of the hardjo serovar in bovine leptospirosis in Rio de Janeiro, Brazil] LA - Por MH - Abortion, Veterinary/epidemiology/*microbiology MH - Agglutination Tests MH - Animal MH - Animal Husbandry/methods MH - Antibodies, Bacterial/blood MH - Brazil/epidemiology MH - Cattle/microbiology MH - Cattle Diseases/epidemiology/*microbiology MH - English Abstract MH - Female MH - Leptospira interrogans/classification/*isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Mastitis, Bovine/epidemiology/*microbiology MH - Pregnancy MH - Prevalence MH - Seroepidemiologic Methods MH - Serotyping RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 960221 DP - 1995 Apr-Jun IS - 0187-4640 TA - Rev Latinoam Microbiol PG - 87-92 CY - MEXICO IP - 2 VI - 37 JC - SEP AA - Author EM - 9604 AB - Four hundred and five serum samples were drawn from cows with reproductive problems which were not vaccinated against leptospirosis from 21 dairy farms. Three distinct geographic regions were determined and the farms were also classified considering the production system, based on technological, zootechnical and sanitary resources. A total of 277 positive reactions were observed, corresponding to 68.39% of the samples. The predominant serovar was hardjo, reactive on 85 samples (20.98%), predominant on nine farms and observed on 17 farms (80.95%). It was observed the predominance of hardjo in all studied regions and on properties classified as type "A" (22 samples) and type "B" (49 samples). The role of this serovar on bovine leptospirosis in Brazil compared with other countries is discussed. AD - Departamento de Microbiologia e Parasitologia, Universidade Federal Fluminense, Rio de Janeiro, Brasil. PMID- 8552880 TT - Leptospirose em reproducao animal: III. Papel do serovar hardjo nas leptospiroses bovinas no Rio de Janeiro, Brasil. EA - A SO - Rev Latinoam Microbiol 1995 Apr-Jun;37(2):87-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 95305353 AU - Whipple DL AU - Bolin CA AU - Davis AJ AU - Jarnagin JL AU - Johnson DC AU - Nabors RS AU - Payeur JB AU - Saari DA AU - Wilson AJ AU - Wolf MM TI - Comparison of the sensitivity of the caudal fold skin test and a commercial gamma-interferon assay for diagnosis of bovine tuberculosis. LA - Eng MH - Animal MH - Cattle MH - Comparative Study MH - Female MH - Interferon Type II/*blood MH - Mycobacterium bovis MH - Reagent Kits, Diagnostic/veterinary MH - Sensitivity and Specificity MH - Skin Tests/methods/*veterinary MH - Tuberculin Test/methods/*veterinary MH - Tuberculosis, Bovine/blood/*diagnosis/pathology RN - 0 (Reagent Kits, Diagnostic) RN - 82115-62-6 (Interferon Type II) PT - JOURNAL ARTICLE DA - 950720 DP - 1995 Apr IS - 0002-9645 TA - Am J Vet Res PG - 415-9 SB - M CY - UNITED STATES IP - 4 VI - 56 JC - 40C AA - Author EM - 9509 AB - A study to determine and compare the sensitivity of the caudal fold tuberculin test (CFT) and a commercial gamma-interferon (gamma-IFN) assay for diagnosis of bovine tuberculosis was conducted. A dairy herd with approximately a third of the cattle infected with Mycobacterium bovis was chosen for this study. All cattle from this herd were slaughtered, and tissue specimens for bacteriologic culturing and histologic examination were collected. Results of the CFT and gamma-IFN assay were compared with results of bacteriologic culturing and histologic examination to determine test sensitivity. Results were analyzed, using each of the following 4 standards to classify cattle as infected: positive test result by bacteriologic culturing only; histologic examination only; bacteriologic culturing and histologic examination; and bacteriologic culturing or histologic examination. Sensitivity of the CFT ranged from 80.4 to 84.4%, depending on the standard of comparison. Sensitivity of the gamma-IFN assay ranged from 55.4 to 97.1%, depending on the standard of comparison and on the method of interpretation. The CFT was significantly (P < 0.001) more sensitive than the gamma-IFN assay for diagnosis of bovine tuberculosis when the gamma-IFN assay was conducted and interpreted as instructed by the manufacturer. Maximum overall sensitivity was achieved when results of the CFT and gamma-IFN assay were interpreted in parallel. AD - Leptospirosis/Mycobacteriosis Research Unit, National Animal Disease Center, USDA, Ames, IA 50010, USA. PMID- 7785813 SO - Am J Vet Res 1995 Apr;56(4):415-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 95303743 AU - Handa R AU - Sood A AU - Wali JP TI - Peritonitis complicating leptospirosis [letter] LA - Eng MH - Adult MH - Alanine Aminotransferase/blood MH - Aspartate Aminotransferase/blood MH - Case Report MH - Human MH - Leptospirosis/*complications/enzymology MH - Male MH - Peritonitis/*etiology RN - EC 2.6.1.1 (Aspartate Aminotransferase) RN - EC 2.6.1.2 (Alanine Aminotransferase) PT - LETTER DA - 950717 DP - 1995 Apr IS - 0032-5473 TA - Postgrad Med J PG - 250 SB - M CY - ENGLAND IP - 834 VI - 71 JC - PFX EM - 9509 PMID- 7784294 SO - Postgrad Med J 1995 Apr;71(834):250 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 95259739 AU - Appassakij H AU - Silpapojakul K AU - Wansit R AU - Woodtayakorn J TI - Evaluation of the immunofluorescent antibody test for the diagnosis of human leptospirosis. LA - Eng MH - Adult MH - Agglutination Tests MH - Antibodies, Bacterial/*blood MH - Child MH - Comparative Study MH - Cross Reactions MH - Evaluation Studies MH - *Fluorescent Antibody Technique MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Sensitivity and Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950606 DP - 1995 Apr IS - 0002-9637 TA - Am J Trop Med Hyg PG - 340-3 SB - A SB - M CY - UNITED STATES IP - 4 VI - 52 JC - 3ZQ AA - Author EM - 9508 AB - Sera from 175 patients with clinically suspected leptospirosis were tested with the immunofluorescent antibody (IFA) assay and compared with the microscopic agglutination (MA) method. Overall, the IFA test recognized all 58 MA-positive patients with leptospirosis. On acute sera testing, the IFA titer > or = 1:100 was 0.97 specific and more sensitive than the conventional MA method (sensitivities = 0.48 versus 0.17, respectively). None of the 117 MA-negative patients, 101 healthy blood donors, and 93 patients with five diseases commonly confused with leptospirosis had IFA titers > or = 1:400. However, cross-reactivity was seen with sera from patients with syphilis. On serial testing, the IFA antibody first appeared during the first week of illness, peaked by the fourth week, and generally decreased below 1:400 after the fourth month. The IFA test appears to be moderately sensitive and specific for the initial diagnosis of leptospirosis. It could replace the more complicated and less sensitive MA assay. AD - Department of Pathology, Faculty of Medicine, Prince of Songkla University, Thailand. PMID- 7741173 SO - Am J Trop Med Hyg 1995 Apr;52(4):340-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 95234973 AU - Douglas JD TI - Salmon farming: occupational health in a new rural industry. LA - Eng MH - Animal MH - Fish Diseases/therapy MH - *Fisheries MH - Human MH - Occupational Diseases/prevention & control MH - *Occupational Health MH - Risk Factors MH - Rural Population MH - *Salmon PT - JOURNAL ARTICLE DA - 950522 DP - 1995 Apr IS - 0962-7480 TA - Occup Med (Oxf) PG - 89-92 CY - ENGLAND IP - 2 VI - 45 JC - A79 AA - Author EM - 9507 AB - The medical hazards of salmon farming can be grouped into those related to marine safety, fish husbandry, fish-farm diving and disease treatments. The hostile water environment requires thermal protection and personal buoyancy aids as workers frequently fall in the water from boats or cages. Feedstuffs may generate respirable dust and attract rats, creating a risk of leptospirosis. Musculo-skeletal injuries are common from lifting nets. Fish-farm diving has particular risks which can be minimized. Organophosphorous pesticides are used to treat sea lice and employees require health surveillance. Fish immunization is required to reduce the incidence of Aeromonas salmonitica. Needlestick injuries when using oil-based vaccines are a serious hazard to employees. The occupational health problems of salmon farming are predictable and preventable with primary safety measures. This new industry is safer than land-based agriculture on current evidence. AD - Tweedale Medical Practice, Fort William, UK. PMID- 7718825 SO - Occup Med (Oxf) 1995 Apr;45(2):89-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 95220526 AU - Groen J AU - Gerding MN AU - Jordans JG AU - Clement JP AU - Nieuwenhuijs JH AU - Osterhaus AD TI - Hantavirus infections in The Netherlands: epidemiology and disease. LA - Eng MH - Adolescence MH - Adult MH - Age Distribution MH - Animal MH - Animals, Domestic/immunology MH - Animals, Wild/immunology MH - Antibodies, Viral/*blood MH - Antigens, Viral/analysis MH - Child MH - Child, Preschool MH - Disease Reservoirs MH - Female MH - Hantavirus/*immunology MH - Hantavirus Infections/*epidemiology/veterinary MH - Human MH - Male MH - Microtinae/immunology MH - Middle Age MH - Netherlands/epidemiology MH - Occupations MH - Prevalence MH - Risk Factors MH - Seasons MH - Seroepidemiologic Methods MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Viral) RN - 0 (Antigens, Viral) PT - JOURNAL ARTICLE DA - 950505 DP - 1995 Apr IS - 0950-2688 TA - Epidemiol Infect PG - 373-83 SB - M CY - ENGLAND IP - 2 VI - 114 JC - EPI AA - Author EM - 9507 AB - A serological survey for the prevalence of hantavirus infections in The Netherlands was carried out on > 10,000 sera, from selected human populations, and different feral and domestic animal species. Hantavirus-specific antibodies were found in about 1% of patients suspected of acute leptospirosis, 10% of patients with acute nephropathia, and in less than 0.1% haemodialysis and renal transplant patients. Among individuals with a suspected occupational risk, 6% of animal trappers, 4% of forestry workers, 2% of laboratory workers and 0.4% of farmers were seropositive. The majority of the seropositive individuals lived in rural and forested areas. The main animal reservoir of the infection was shown to be the red bank vole (Clethrionomys glareolus). Epidemiological, clinical and laboratory findings seen in serologically confirmed human cases were similar to those associated with nephropathia epidemica. AD - Department of Clinical Virology, University Hospital Rotterdam, The Netherlands. PMID- 7705497 SO - Epidemiol Infect 1995 Apr;114(2):373-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 95407078 AU - Stabel JR TI - Temporal effects of tumor necrosis factor-alpha on intracellular survival of Mycobacterium paratuberculosis. LA - Eng MH - Animal MH - Cell Line MH - Colony Count, Microbial MH - Dose-Response Relationship, Drug MH - Macrophages/cytology/*drug effects/*microbiology MH - Mice MH - Mycobacterium paratuberculosis/*drug effects/*growth & development/isolation & purification MH - Phagocytosis MH - Recombinant Proteins MH - Time Factors MH - Tumor Necrosis Factor/*pharmacology RN - 0 (Recombinant Proteins) RN - 0 (Tumor Necrosis Factor) PT - JOURNAL ARTICLE DA - 951017 DP - 1995 Apr IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 321-32 SB - M CY - NETHERLANDS IP - 3-4 VI - 45 JC - XCB AA - Author EM - 9512 AB - The causative agent in Johne's disease is Mycobacterium paratuberculosis, an intracellular pathogen which causes enteritis in ruminants. Little is known about interactions between the host cell (macrophage) and M. paratuberculosis; however, this bacterium is able to evade normal host immune defenses and cause a chronic infective state. In the present study, we evaluated whether activation of a murine macrophage cell line (J774.16) by pretreatment with recombinant murine tumor necrosis factor alpha (TNF) prior to infection with M. paratuberculosis would affect their ability to restrict growth and kill the ingested bacteria. A murine cell line was utilized owing to difficulty in obtaining bovine reagents and lack of a continuous bovine macrophage cell line for repeated experimentation. After 4 h of infection, numbers of viable bacteria in cell lysates were significantly lower for macrophages pretreated with 1000 IU TNF ml-1. The rate of bacterial growth as assessed by BACTEC radiometric culture system was also reduced at this time point. Upon further extension of the infection period to 72 h, we observed that moderate doses of TNF (10-1000 IU ml-1) significantly increased the number of viable M. paratuberculosis recovered whereas the highest dose of TNF (4000 IU ml- 1) effectively reduced bacterial numbers. These data indicate that TNF can either enhance or reduce macrophage mycobactericidal and mycobacteriostatic activity depending upon both the level of TNF to which cells are exposed and the duration of infection. AD - Leptospirosis and Mycobacteriosis Research Unit, National Animal Disease Center, USDA-ARS, Ames, IA 50010, USA. PMID- 7676613 SO - Vet Immunol Immunopathol 1995 Apr;45(3-4):321-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 96029118 AU - Andreescu N AU - Filiu P TI - [Human leptospirosis in Romania in 1985-1994] LA - Rum MH - Animal MH - Disease Vectors MH - Human MH - Incidence MH - Leptospirosis/*epidemiology/transmission MH - Mice MH - Rats MH - Romania/epidemiology MH - Swine MH - Weil's Disease/*epidemiology/transmission PT - JOURNAL ARTICLE DA - 951103 DP - 1995 Apr-Jun TA - Bacteriol Virusol Parazitol Epidemiol PG - 131-4 CY - ROMANIA IP - 2 VI - 40 JC - BFP EM - 9601 AD - Institutul Cantacuzino. PMID- 7549255 TT - Leptospirozele umane in Romania in perioada 1985-1994. SO - Bacteriol Virusol Parazitol Epidemiol 1995 Apr-Jun;40(2):131-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 95314407 AU - Delacollette C AU - Taelman H AU - Wery M TI - An etiologic study of hemoglobinuria and blackwater fever in the Kivu Mountains, Zaire. LA - Eng MH - Adolescence MH - Adult MH - Blackwater Fever/blood/*etiology MH - Child MH - Chloroquine/therapeutic use MH - Female MH - Glucosephosphate Dehydrogenase Deficiency/complications MH - Hemoglobinuria/*etiology MH - Hemorrhagic Fever with Renal Syndrome/complications MH - Human MH - Leptospirosis/complications MH - Malaria, Falciparum/*complications/drug therapy MH - Male MH - Quinine/adverse effects/therapeutic use RN - 130-95-0 (Quinine) RN - 54-05-7 (Chloroquine) PT - JOURNAL ARTICLE DA - 950727 DP - 1995 Mar IS - 0365-6527 TA - Ann Soc Belg Med Trop PG - 51-63 CY - BELGIUM IP - 1 VI - 75 JC - 66K AA - Author EM - 9509 AB - Between January 1985 and March 1986, in the high altitude area of Kivu, Eastern Zaire, 38 patients presenting with hemoglobinuria as main manifestation were investigated. Profound glucose-6-phosphate dehydrogenase deficiency was detected in 4 patients, leptospirosis in 2 and Hantaan virus infection in 2. Hemolysis was doubtful (haptoglobin > 40 mg/dl, Hemoglobin > 12 g/dl) in 2 patients. Other potential causes of hemoglobinuria such as hemoglobinopathy, toxic agents, infectious diseases or blood transfusion incompatibility were carefully screened and excluded. The syndrome observed in the remaining 28 cases was strongly suggestive of blackwater fever (BWF) as described in malaria patients by several authors under the french name "fievre bilieuse hemoglobinurique". Quinine was used as curative treatment of malaria before admission in a significant greater proportion (p < 0.01) of patients with BWF compared to patients with uncomplicated malaria, suggesting that this drug might have played a triggering role in the genesis of BWF. However, quinine was usually administered at inadequate doses to malaria patients non responding to chloroquine and belonging to a population of whom 50% are non immune. It may thus also be hypothesized that BWF in our patients could result from a hyperparasitemic state that remained undetected because of an unusual synchronous lysis of infected erythrocytes. In the latter case BWF would correspond to a major complication of falciparum malaria only coincidentally related to the use of quinine. AD - Lutte contre les Maladies Transmissibles et Carentielles, Bujumbura, Burundi. PMID- 7794063 SO - Ann Soc Belg Med Trop 1995 Mar;75(1):51-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [222 medline neighbors] UI - 95234471 AU - Valvini EM AU - Young JD TI - Serum nitrogen oxides during nitric oxide inhalation. LA - Eng MH - Administration, Inhalation MH - Adult MH - Case Report MH - Human MH - Kidney Failure, Acute/metabolism MH - Leptospirosis/*blood/metabolism MH - Male MH - Nitrates/*blood MH - Nitric Oxide/*administration & dosage/metabolism MH - Nitrites/*blood MH - Support, Non-U.S. Gov't RN - 0 (Nitrates) RN - 0 (Nitrites) RN - 10102-43-9 (Nitric Oxide) PT - JOURNAL ARTICLE DA - 950522 DP - 1995 Mar IS - 0007-0912 TA - Br J Anaesth PG - 338-9 SB - M CY - ENGLAND IP - 3 VI - 74 JC - AUO AA - Author EM - 9507 AB - A patient with acute respiratory failure secondary to leptospirosis was treated with 40 and 90 volumes per million inhaled nitric oxide. His serum nitrogen oxide concentration (nitrates and nitrites combined) increased 13-fold. The mechanisms for the formation and elimination of nitrates are discussed. AD - Dialysis Unit, Middlesex Hospital, London. PMID- 7718385 SO - Br J Anaesth 1995 Mar;74(3):338-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 95386166 AU - Jiang N AU - Jin B AU - Dai B AU - Zhang Y TI - [Identification of pathogenic and nonpathogenic leptospires by recombinant DNA probe] LA - Chi MH - DNA Probes MH - DNA, Bacterial/*analysis MH - DNA, Recombinant MH - English Abstract MH - Gene Library MH - Leptospira interrogans/genetics/*isolation & purification MH - Support, Non-U.S. Gov't MH - Virulence RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) RN - 0 (DNA, Recombinant) PT - JOURNAL ARTICLE DA - 951005 DP - 1995 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 1-5 CY - CHINA IP - 1 VI - 26 JC - GEB AA - Author EM - 9512 AB - A gene bank of L. interrogans serovar lai strain 017 was constructed with plasmid vector pUC 18. Recombinant plasmids designated pDJ 6 and pDJ 8 were screened from the gene bank. Inserted fragments of them are 1.9kb and 2.2kb respectively. Diglabelled 1.9kb inserted fragment of pDJ 6. Results showed that the probe had hybridization with pathogenic leptospires, but it did not have hybridization with nonpathogenic leptospires such as L. biflexa strain Patoc I and Leptonema illini. The probe did not have hybridization with nonhomologous DNA (e.g. human leucocyte and E. coli JM 103), either. So, the recombinant probe is a good tool for distinguishing and identifying genus, species, pathogenic leptospires and nonpathogenic leptospires. PMID- 7657322 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1995 Mar;26(1):1-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 95381660 AU - Shamardin VA AU - Rud' NV AU - Il'iasov BK TI - [The effectiveness of immunological methods in the diagnosis of leptospirosis] LA - Rus MH - Animal MH - Antibodies, Bacterial/blood MH - Comparative Study MH - English Abstract MH - Evaluation Studies MH - Horse Diseases/*diagnosis MH - Horses MH - Human MH - Immunologic Tests/methods/statistics & numerical data MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/*veterinary MH - Meat-Packing Industry MH - Occupational Diseases/diagnosis MH - Sensitivity and Specificity MH - Swine MH - Swine Diseases/*diagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950928 DP - 1995 Mar-Apr IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 84-6 SB - M CY - RUSSIA IP - 2 JC - Y9O AA - Author EM - 9512 AB - The effectiveness of Leptospira antigenic erythrocyte diagnosticum increases 4- to 8-fold due to the preliminary activation of erythrocytes and Boivin's antigen with 0.001-0.002 M solution of potassium periodate. ELISA with the use of conjugate based on antiglobulin serum and catalase is twice as sensitive as ELISA with conjugate on the basis of penicillinase, 3 times as sensitive as ELISA with conjugate on the basis of Leptospira hyperimmune serum and catalase and 10-20 times as sensitive as the passive hemagglutination test and the microagglutination and lysis test. PMID- 7653145 TT - Effektivnost' nekotorykh immunologicheskikh metodov v diagnostike leptospiroza. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1995 Mar-Apr;(2):84-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 95172169 AU - Webster JP AU - Ellis WA AU - Macdonald DW TI - Prevalence of Leptospira spp. in wild brown rats (Rattus norvegicus) on UK farms. LA - Eng MH - Animal MH - Animals, Wild/microbiology MH - Antibodies, Bacterial/blood MH - Bacteriological Techniques/veterinary MH - Female MH - Great Britain/epidemiology MH - Leptospira/classification/immunology/*isolation & purification MH - Male MH - Prevalence MH - Rats/*microbiology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950328 DP - 1995 Feb IS - 0950-2688 TA - Epidemiol Infect PG - 195-201 SB - M CY - ENGLAND IP - 1 VI - 114 JC - EPI AA - Author EM - 9506 AB - Wild brown rats (Rattus norvegicus) are frequently implicated in the carriage and spread of Leptospira spp. Wild brown rats (n = 259) were trapped from 11 UK farms and tested for Leptospira spp. using a number of diagnostic tests. The prevalence of leptospiral infection was low, but there was variation in the results obtained with the different diagnostic tests. Estimates of prevalence ranged between 0% by silver- staining of tissues, 1% by the microscopic agglutination test, 4% by the enzyme-linked immunosorbent assay, 4% by culture, and 8% by fluorescent antibody technique. In total, 37 (14%) rats were positive by at least one of the tests, which contrasts with the frequently reported prevalences of 50-70% for wild rats in the UK. Serovar bratislava was a prevalent as icterohaemorrhagiae, although it was present only on farms with larger rat populations. AD - Department of Zoology, University of Oxford. PMID- 7867738 SO - Epidemiol Infect 1995 Feb;114(1):195-201 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 96104941 AU - Antoniadis A AU - Alexiou-Daniel S AU - Fidani L AU - Bautz EF TI - Comparison of the clinical and serologic diagnosis of haemorrhagic fever with renal syndrome (HFRS) and leptospirosis [letter] LA - Eng MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/analysis MH - Comparative Study MH - Diagnosis, Differential MH - Fluorescent Antibody Technique, Indirect MH - Hantavirus/immunology MH - Hemorrhagic Fever with Renal Syndrome/*diagnosis MH - Human MH - IgG/analysis MH - IgM/analysis MH - Leptospira/immunology MH - Leptospirosis/*diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) RN - 0 (IgG) RN - 0 (IgM) PT - LETTER DA - 960102 DP - 1995 Feb IS - 0392-2990 TA - Eur J Epidemiol PG - 91-2 SB - M CY - NETHERLANDS IP - 1 VI - 11 JC - ERE EM - 9603 PMID- 7489781 SO - Eur J Epidemiol 1995 Feb;11(1):91-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 95133101 AU - Biegel E AU - Mortensen H AU - Gaub J TI - [Leptospirosis in the Ribe County 1980-1991] LA - Dan MH - Adult MH - Denmark/epidemiology MH - Diagnosis, Differential MH - English Abstract MH - Female MH - Human MH - Leptospirosis/diagnosis/drug therapy/*epidemiology MH - Male MH - Middle Age MH - Prognosis MH - Retrospective Studies PT - JOURNAL ARTICLE DA - 950223 DP - 1995 Jan 9 IS - 0041-5782 TA - Ugeskr Laeger PG - 157-61 CY - DENMARK IP - 2 VI - 157 JC - WM8 AA - Author EM - 9504 AB - Though only 4.2% of the Danish population live in Ribe County, 12 cases of leptospirosis (22% of the Danish total) were found in the county between 1980-1991. Nine cases were associated with fresh water angling or fish farming. The patients were typically young or middle-aged formerly healthy men, who suddenly became ill with acute febrile disease. Eleven patients survived, one died. Cases were most often seen in late summer and autumn. Four patients required dialysis, and these patients also had relatively high serum levels of bilirubin. Case history and simple laboratory findings are helpful in leading to the diagnosis. Three patients were admitted with the correct diagnosis, and by the third day in hospital all 12 were being treated with relevant antibiotics, eight on suspicion of leptospirosis. Three patients had positive blood cultures on day 4, 6 and 9, and nine patients had late positive serology, two of whom also belonged to the group with positive blood cultures. In two patients the diagnosis was based on clinical findings alone. For these reasons, penicillin should be commenced on clinical suspicion alone. AD - Esbjerg Centralsygehus, medicinsk afdeling. PMID- 7831727 TT - Leptospirose i Ribe Amt 1980-1991. EA - A SO - Ugeskr Laeger 1995 Jan 9;157(2):157-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 95133100 AU - Biegel E AU - Mortensen H TI - [Leptospirosis] LA - Dan MH - Animal MH - Communicable Disease Control MH - English Abstract MH - Human MH - *Leptospirosis/drug therapy/epidemiology/microbiology/prevention & control MH - Prognosis MH - Rats MH - World Health MH - Zoonoses PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 950223 DP - 1995 Jan 9 IS - 0041-5782 TA - Ugeskr Laeger PG - 153-7 CY - DENMARK IP - 2 VI - 157 JC - WM8 AA - Author EM - 9504 AB - Leptospirosis is a worldwide zoonosis. When human beings are infected the clinical spectrum varies from a mild, febrile illness to severe, icteric disease with multiorgan failure and fatal outcome. The illness falls into two phases, the septicaemic and the so-called immune. The diagnosis is confirmed by culture of blood and spinal fluid during the first phase, by culture of urine during the second and by serology. It is recommended that penicillin be given as quickly as possible. Prevention is important e.g. effective rat control and individual protection such as wearing protective clothing in contaminated work areas. AD - Esbjerg Centralsygehus, medicinsk afdeling. RF - 32 PMID- 7831726 TT - Leptospirose. EA - A SO - Ugeskr Laeger 1995 Jan 9;157(2):153-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 96381038 AU - Ishii N AU - Isogai E AU - Isogai H AU - Kimura K AU - Nishikawa T AU - Fujii N AU - Nakajima H TI - T cell response to Borrelia garinii, Borrelia afzelii, and Borrelia japonica in various congenic mouse strains. LA - Eng MH - Animal MH - Antibodies, Monoclonal MH - Antigens, Bacterial MH - Base Sequence MH - Borrelia/*immunology/pathogenicity MH - Borrelia Infections/etiology/immunology MH - Comparative Study MH - Cross Reactions MH - DNA Primers/genetics MH - DNA, Bacterial/genetics MH - Human MH - Hypersensitivity, Delayed MH - Immunotherapy, Adoptive MH - Japan MH - Mice MH - Mice, Inbred BALB C MH - Mice, Inbred C3H MH - Mice, Inbred C57BL MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - Species Specificity MH - T-Lymphocytes/*immunology RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 961021 DP - 1995 IS - 0385-5600 TA - Microbiol Immunol PG - 929-35 SB - M CY - JAPAN IP - 12 VI - 39 JC - MX7 AA - Author EM - 9612 AB - The infectivity and T cell response to Borrelia garinii SIKA2, Borrelia afzelii BFOX, and Borrelia japonica 0612, the organisms that cause Lyme disease in Japan, were examined in various inbred and congenic strains of mice. Infectivity differed among the species: B. garinii SIKA2 and B. afzelii BFOX were each able to infect 90% to 100% of C3H/He mice; B. japonica 0612 was able to infect only 20% of C3H/He mice. The pattern of infectivity to various inbred and congenic strains of mice may influence the pathogenicity of the organism and the clinical signs of Lyme disease. Cross-reactivity between Borrelia antigens was observed, but there was no cross-reactivity between Borrelia antigens and Leptospira antigens. We evaluated the genetic control of the delayed- type hypersensitivity (DTH) reaction in the form of footpad swelling produced by Borrelia antigens using viable or sonicated bacteria as sensitization. Differences in strains of mice infected by viable antigen were observed. However, all strains of mice showed a strong DTH reaction using sonicated antigens without genetic background. A DTH reaction in the form of footpad swelling did not appear to be associated with genetic background. The footpad reaction was mediated by CD4+8- and Ia- T cells, as revealed by in vitro monoclonal antibody treatment. However, CD8+ T cells did not suppress footpad swelling. These results indicate that many antigenic epitopes of the Borrelia spirochete can stimulate the DTH reaction. AD - Department of Dermatology, Yokohama City University School of Medicine, Japan. PMID- 8789051 SO - Microbiol Immunol 1995;39(12):929-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96238395 AU - Zylberberg H AU - Nebut M AU - Hagege H AU - Geslin P AU - Chousterman M TI - [Severe leptospirosis in a patient with human immunodeficiency virus infection (letter)] LA - Fre MH - Adult MH - *AIDS-Related Opportunistic Infections MH - Case Report MH - Human MH - HIV Infections/*complications/microbiology MH - Leptospirosis/*etiology MH - Male PT - LETTER DA - 960924 DP - 1995 IS - 0003-410X TA - Ann Med Interne (Paris) PG - 522 SB - M CY - FRANCE IP - 7 VI - 146 JC - 5FZ EM - 9611 PMID- 8787297 TT - Leptospirose grave chez un patient infecte par le virus de l'immunodeficience humaine. SO - Ann Med Interne (Paris) 1995;146(7):522 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 96348314 AU - Sakurai Y TI - [Leptospirosis, Weil's disease] LA - Jpn MH - Antibiotics, Aminoglycoside/therapeutic use MH - Diagnosis, Differential MH - Human MH - *Liver Diseases/diagnosis/drug therapy/physiopathology MH - Prognosis MH - Streptomycin/therapeutic use MH - *Weil's Disease/diagnosis/drug therapy/physiopathology RN - 0 (Antibiotics, Aminoglycoside) RN - 57-92-1 (Streptomycin) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 961004 DP - 1995 TA - Ryoikibetsu Shokogun Shirizu PG - 115-7 CY - JAPAN IP - 7 JC - CAY EM - 9612 AD - Division of Gastroenterology, Kantoh-Teishin Hospital, Japan. RF - 11 PMID- 8749432 SO - Ryoikibetsu Shokogun Shirizu 1995;(7):115-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 96203266 AU - Canak G AU - Vukobratov Z AU - Dordevic M AU - Madle-Samardzija N AU - Ilic A AU - Doder R TI - [Leptospirosis at the Clinic for Infectious Diseases in Novi Sad 1984- 1993] LA - Scr MH - Adolescence MH - Adult MH - Aged MH - Child MH - English Abstract MH - Female MH - Human MH - *Leptospirosis/diagnosis/therapy MH - Male MH - Middle Age MH - Retrospective Studies PT - JOURNAL ARTICLE DA - 960625 DP - 1995 IS - 0025-8105 TA - Med Pregl PG - 323-5 CY - YUGOSLAVIA IP - 9-10 VI - 48 JC - M8U AA - Author EM - 9608 AB - We examined the clinical picture and course of leptospiral infections in 50 patients treated at the Clinic during the period 1984-1993. Most patients were 11-20 years of age (9 years the youngest and 77 years the oldest, mean age being 25.16). The disease more often occurred in male patients, 44 (88%). There were 30 (60%) patients with gastrointestinal symptoms, while 21 (42%) had liver and kidney infections. Meningeal syndrome was established in 25 (50%) and serous meningitis in 13 (26%). Leptospiral infections represented average and serious infections with complications in 8 (16%) patients, successful treatment in 47 (94%) patients while 3 (6%) patients died due to hematorenal insufficiency. AD - Klinika za infektivne i dermatoveneroloske bolestic, Medicinski fakultet, Novi Sad. PMID- 8628188 TT - Leptospiroze na Klinici za infektivne bolesti u Novom Sadu u periodu 1984-1993. godine. EA - A SO - Med Pregl 1995;48(9-10):323-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [14 medline neighbors] UI - 96118292 AU - Giacometti M AU - Tolari F AU - Mannelli A AU - Lanfranchi P TI - [Seroepidemiologic investigations in the Alpine ibex (Capra i. ibex) of Piz Albris in the canton of Grigioni (Switzerland)] LA - Ita MH - Animal MH - Animals, Wild MH - Communicable Diseases/epidemiology/*veterinary MH - English Abstract MH - Goat Diseases/*epidemiology MH - Goats MH - Prevalence MH - Seroepidemiologic Methods MH - Support, Non-U.S. Gov't MH - Switzerland/epidemiology PT - JOURNAL ARTICLE DA - 960321 DP - 1995 IS - 0036-7281 TA - Schweiz Arch Tierheilkd PG - 537-42 CY - SWITZERLAND IP - 12 VI - 137 JC - UE5 AA - Author EM - 9605 AB - Sero-epidemiological investigations in wild animals may allow to assess distribution of selected pathogens that sometimes seem to be involved in sanitary interrelationships between wild and domestic ungulates sharing the same areas. Serological studies were carried out to investigate the prevalence of antibody against 8 pathogens in Alpine ibex of Albris colony (Grisons, Switzerland). Investigated sera came from 89 animals shot by gamekeepers in 1990-1991. Antibody against smooth Brucella, Coxiella burnetti, Leptospira interrogans, Borrelia Burgdorferi, Mycobacterium paratuberculosis, BHV-1 and ovine-caprine lentiviruses were not detected in the tested sera. However, 31% of sera analysed were found to be positive for Chlamydia psittaci. Three sera showed high antibody titres ( > or = 1/128) suggestive of active infection in the animals. Any influence of Chlamydia psittaci in reproductive performance of free-ranging alpine ibex should be investigated through isolation of the agent. Results are discussed with reference to methods used and with epidemiological picture in Switzerland and were compared with results of serological investigations carried out in ibex in Italy and France. AD - Untersuchungsstelle fur Wildtierkrankheiten, Institut fur Tierpathologie der Universitat Bern. PMID- 8584868 TT - Indagini sieroepidemiologiche su stambecchi (Capra i. ibex) del Piz Albris nel Cantone dei Grigioni (Svizzera). EA - A SO - Schweiz Arch Tierheilkd 1995;137(12):537-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 96171828 AU - Roshchupkin VI AU - Suzdal'tsev AA AU - Iakimakha GL AU - Baranov BA AU - Vekhova EV AU - Serbina VA AU - Eroshevskaia MI TI - [A trichinelliasis outbreak in Samara Province] LA - Rus MH - Acute Disease MH - Adult MH - Case Report MH - Diagnosis, Differential MH - *Disease Outbreaks MH - Female MH - Human MH - Leptospirosis/diagnosis MH - Male MH - Middle Age MH - Russia/epidemiology MH - Time Factors MH - Trichinosis/diagnosis/*epidemiology PT - JOURNAL ARTICLE DA - 960314 DP - 1995 IS - 0023-2149 TA - Klin Med (Mosk) PG - 55-6 CY - RUSSIA IP - 3 VI - 73 JC - KW2 EM - 9605 PMID- 8577112 TT - Vspyshka trikhinelleza v Samarskoi oblasti. SO - Klin Med (Mosk) 1995;73(3):55-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96141162 TI - [Leptospirosis and vaccination] LA - Fre MH - Clinical Trials MH - Human MH - Leptospirosis/epidemiology/*prevention & control MH - Tropical Climate MH - *Vaccination PT - JOURNAL ARTICLE DA - 960223 DP - 1995 IS - 0025-682X TA - Med Trop (Mars) PG - 208 SB - M CY - FRANCE IP - 3 VI - 55 JC - MHQ EM - 9605 PMID- 8559011 NI - A TT - Leptospiroses et vaccination. SO - Med Trop (Mars) 1995;55(3):208 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 95196448 AU - Andre-Fontaine G AU - Monfort P AU - Buggin-Daubie M AU - Filloneau C AU - Ganiere JP TI - Fatal disease mimicking leptospirosis in a dog, caused by Aeromonas hydrophila. LA - Eng MH - *Aeromonas hydrophila/isolation & purification MH - Animal MH - Case Report MH - Dog Diseases/*microbiology MH - Dogs MH - Fatal Outcome MH - Gram-Negative Bacterial Infections/*veterinary MH - Kidney/microbiology MH - Leptospirosis/diagnosis MH - Liver/microbiology PT - JOURNAL ARTICLE DA - 950417 DP - 1995 Jan IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 69-72 SB - M CY - ENGLAND IP - 1 VI - 18 JC - DNN AA - Author EM - 9506 AB - A dog was treated for leptospirosis on clinical and epidemiological arguments. The amoxicillin treatment was not successful. Pure culture of Aeromonas hydrophila was then obtained from liver and kidney, indicating that the septicemia was due to this bacteria commonly found in waters. AD - Ecole Nationale Veterinaire, Nantes, France. PMID- 7889733 SO - Comp Immunol Microbiol Infect Dis 1995 Jan;18(1):69-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 95298941 AU - Donahue JM AU - Smith BJ AU - Poonacha KB AU - Donahoe JK AU - Rigsby CL TI - Prevalence and serovars of leptospira involved in equine abortions in central Kentucky during the 1991-1993 foaling seasons. LA - Eng MH - Abortion, Veterinary/*epidemiology/*microbiology MH - Animal MH - Animals, Newborn MH - Female MH - Fetal Death/veterinary MH - Fluorescent Antibody Technique MH - *Horse Diseases MH - Horses MH - Kentucky/epidemiology MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/epidemiology/microbiology/*veterinary MH - Prevalence MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 950718 DP - 1995 Jan IS - 1040-6387 TA - J Vet Diagn Invest PG - 87-91 SB - M CY - UNITED STATES IP - 1 VI - 7 JC - A2D AA - Author EM - 9509 AB - In this study, the prevalence of leptospira-induced abortions/stillbirths for the past 3 foaling seasons (1991-1993) was determined, and fetal tissues and/or the mare's urine from positive cases were cultured in an attempt to isolate and identify the leptospira serovars responsible for the abortions. The sensitivity and specificity of the primary diagnostic tests, the fluorescent antibody test (FAT) and the microscopic agglutination test (MAT), used for the diagnosis of leptospirosis were also determined. For the 3 years, 74 (3.3%) of 2,264 abortion/stillborn submissions were diagnosed as leptospirosis. Twelve cases occurred in the 1991, 19 in the 1992, and 43 in the 1993 foaling seasons. Leptospires were isolated from 45 (60.8%) of the 74 cases, and they were identified as serovar kennewicki (43 cases), serovar grippotyphosa (1 case), and a serovar similar to pomona (1 case). Of the 29 culture-negative cases, serologic results indicated that leptospires in the Pomona serogroup (kennewicki is a member of this serogroup) were responsible for 25 abortions, leptospires in the Grippotyphosa serogroup for 1 abortion, and leptospires in the Sejroe serogroup for 1 abortion. The specificities of the FAT on fetal tissues and mare's placenta and of the MAT on fetal fluid were 100%. The sensitivity of the FAT was 98.7%, and that of the MAT was 81.3%. AD - Department of Veterinary Science, College of Agriculture, University of Kentucky, Lexington 40511, USA. PMID- 7779971 SO - J Vet Diagn Invest 1995 Jan;7(1):87-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 95280752 AU - Dettori G AU - Grillo R AU - Cattani P AU - Calderaro A AU - Chezzi C AU - Milner J AU - Truelove K AU - Sellwood R TI - Comparative study of the enzyme activities of Borrelia burgdorferi and other non-intestinal and intestinal spirochaetes. LA - Eng MH - Animal MH - Borrelia burgdorferi/*enzymology/isolation & purification MH - Comparative Study MH - Human MH - Hydrolases/*metabolism MH - Intestines/microbiology MH - Leptospira/enzymology/isolation & purification MH - Serpulina/enzymology/isolation & purification MH - Spirochaeta/*enzymology MH - Support, Non-U.S. Gov't MH - Treponema/enzymology/isolation & purification RN - EC 3. (Hydrolases) PT - JOURNAL ARTICLE DA - 950627 DP - 1995 Jan IS - 1121-7138 TA - New Microbiol PG - 13-26 SB - M CY - ITALY IP - 1 VI - 18 JC - CGC AA - Author EM - 9509 AB - Comparative analysis of the enzymatic profiles of 58 spirochaetal isolates clearly differentiated borrelias from leptospires, serpulinas and a treponeme. Strains of both Borrelia burgdorferi and Borrelia hermsii characteristically produced significant amounts of leucine arylamidase. This enzyme activity was not unique to borrelias but was also detected amongst pathogenic and non-pathogenic leptospira serovars. This fact, however, did not hamper a correct differentiation of borrelias from these spirochaetes, because leptospires possessed unique enzyme profiles. The API ZYM system could not differentiate the human strains of B. burgdorferi from those isolated from ticks, or from B. hermsii. Treponema phagedenis could be differentiated from all the other spirochaetes by the production of alpha-fucosidase. Our results confirm and extend previous studies indicating that human and animal intestinal spirochaetes have many common enzyme activities. All strains produced reactions of maximum intensity when tested for the presence of beta-galactosidase activity. However the avian strains lacked esterase (C4) which was present in human and swine intestinal spirochaetes. All strains of Serpulina hyodysenteriae, and Serpulina innocens as well as the human intestinal spirochaete strain HRM-14 showed alpha and beta glucosidase activity. Both enzyme activities were absent or insignificant in most other intestinal spirochaetes examined: 25 different human strains, non-pathogenic swine strain M1 and the avian strain 4742. However, swine strain LL3 and avian strain 1380 showed some beta-glucosidase activity. AD - Institute of Microbiology, Medical Faculty, Parma, Italy. RO - M:CNR PMID- 7760753 LR - 960123 SO - New Microbiol 1995 Jan;18(1):13-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 95277034 AU - Mel'nik GV AU - Lebedev VV AU - Avdeev MG AU - Degtiar' LD AU - Korotaeva OA TI - [Clinical features and cellular immunity in patients with icterohemorrhagic leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Comparative Study MH - English Abstract MH - Female MH - Human MH - Lymphocyte Count MH - Lymphocyte Subsets MH - Male MH - Middle Age MH - Prognosis MH - Rosette Formation MH - T-Lymphocytes/immunology MH - Weil's Disease/diagnosis/*immunology PT - JOURNAL ARTICLE DA - 950626 DP - 1995 Jan-Feb IS - 0869-2084 TA - Klin Lab Diagn PG - 29-31 CY - RUSSIA IP - 1 JC - B17 AA - Author EM - 9509 AB - Time course of cellular immunity parameters was followed up in 56 patients with different forms of icterohemorrhagic leptospirosis of various severity. A grave course of the disease was associated with development of secondary structural immunodeficiency manifesting by reduction of E = RFC count, of immunoregulatory index, and of the count of T lymphocytes. The course of convalescence was found related to the immune response: if immunodeficiency persisted during the early convalescence period, the patients developed late complications. PMID- 7757363 TT - Klinicheskaia kartina i kletochnyi immunitet u bol'nykh ikterogemorragicheskim leptospirozom. EA - A SO - Klin Lab Diagn 1995 Jan-Feb;(1):29-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 95378594 AU - Carles G AU - Montoya E AU - Joly F AU - Peneau C TI - [Leptospirosis and pregnancy. Eleven cases in French Guyana] LA - Fre MH - Case Report MH - *Disease Transmission, Vertical MH - English Abstract MH - Female MH - Fetal Death/microbiology MH - French Guiana MH - Human MH - Incidence MH - Leptospirosis/complications/*diagnosis/transmission MH - Pregnancy MH - Pregnancy Complications, Infectious/*diagnosis PT - JOURNAL ARTICLE DA - 950928 DP - 1995 IS - 0368-2315 TA - J Gynecol Obstet Biol Reprod (Paris) PG - 418-21 SB - M CY - FRANCE IP - 4 VI - 24 JC - IAZ AA - Author EM - 9512 AB - The incidence of leptospirosis, a widespread antropozoonosis, is underestimated due to variable clinical presentations. The abortive effect of this disease, well known in animals, is only reported rarely in humans although transplacental transmission has been demonstrated. We report 11 cases of leptospirosis in pregnant women in French Guiana. The diagnosis was made on identification of the germ in maternal urine samples and/or on specific serology tests. Fetal death occurred in more than 50% of the cases due to premature abortion or in utero death. The rate of maternal-fetal transmissions is not known, but leptospirosis could be a not uncommon cause of perinatal deaths in endemic zones. AD - Service de Gynecologie-Obstetrique, Centre Hospitalier Andre-Bouron, Saint-Laurent-du-Maroni, Guyane Francaise. PMID- 7650320 TT - Leptospiroses et grossesse. Etude de 11 cas en Guyane Francaise. EA - A SO - J Gynecol Obstet Biol Reprod (Paris) 1995;24(4):418-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96090557 AU - Andreescu N TI - [The serological diagnosis of human leptospirosis] LA - Rum MH - Agglutination Tests/instrumentation/methods/standards MH - Antigens, Bacterial/immunology MH - Complement Fixation Tests/instrumentation/methods/standards MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis MH - Reference Standards RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 951218 DP - 1995 Jan-Mar TA - Bacteriol Virusol Parazitol Epidemiol PG - 51-8 CY - ROMANIA IP - 1 VI - 40 JC - BFP EM - 9602 AD - Institutul Cantacuzino. PMID- 7579950 TT - Diagnosticul serologic al leptospirozelor umane. SO - Bacteriol Virusol Parazitol Epidemiol 1995 Jan-Mar;40(1):51-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 95208180 AU - Reilly GA AU - Bailie NC AU - Morrow WT AU - McDowell SW AU - Ellis WA TI - Feline stillbirths associated with mixed Salmonella typhimurium and leptospira infection [letter] LA - Eng MH - Animal MH - Case Report MH - Cat Diseases/*microbiology MH - Cats MH - Female MH - Fetal Death/etiology/*veterinary MH - Food Microbiology MH - Leptospirosis/complications/*veterinary MH - Pregnancy MH - Salmonella Infections, Animal/*complications PT - LETTER DA - 950425 DP - 1994 Dec 17 IS - 0042-4900 TA - Vet Rec PG - 608 SB - M CY - ENGLAND IP - 25 VI - 135 JC - XBS EM - 9506 PMID- 7900252 SO - Vet Rec 1994 Dec 17;135(25):608 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 95048783 AU - Midwinter A AU - Vinh T AU - Faine S AU - Adler B TI - Characterization of an antigenic oligosaccharide from Leptospira interrogans serovar pomona and its role in immunity. LA - Eng MH - Agglutination/immunology MH - Amino Sugars/analysis MH - Animal MH - Antibodies, Bacterial/*blood MH - Antigens, Bacterial/*immunology MH - Diphtheria Toxoid/immunology MH - Female MH - Immunoblotting MH - Immunoenzyme Techniques MH - Leptospira interrogans/classification/*immunology MH - Lipopolysaccharides/chemistry/*immunology MH - Macrophage Activation MH - Mice MH - Mice, Inbred BALB C MH - Monosaccharides/analysis MH - Oligosaccharides/*immunology MH - Opsonins/immunology MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Amino Sugars) RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Diphtheria Toxoid) RN - 0 (Lipopolysaccharides) RN - 0 (Monosaccharides) RN - 0 (Oligosaccharides) RN - 0 (Opsonins) PT - JOURNAL ARTICLE DA - 941229 DP - 1994 Dec IS - 0019-9567 TA - Infect Immun PG - 5477-82 SB - M SB - X CY - UNITED STATES IP - 12 VI - 62 JC - GO7 AA - Author EM - 9502 AB - An antigenic oligosaccharide fraction derived from the lipopolysaccharide of Leptospira interrogans serovar pomona was isolated by endo-glycosidase H digestion and column chromatography. The oligosaccharide contained rhamnose, ribose, glucose, and glucosamine and inhibited the binding of opsonic, protective monoclonal antibodies directed against the lipopolysaccharide. When conjugated to diphtheria toxoid, the oligosaccharide elicited the production of agglutinating, opsonic antibodies. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 7960129 SO - Infect Immun 1994 Dec;62(12):5477-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 95263033 AU - Shen C AU - Dai B TI - [Specificity of the recombinant DNA pCX7 and its restriction enzyme map] LA - Chi MH - DNA, Bacterial/*genetics MH - DNA, Recombinant/*genetics MH - English Abstract MH - Leptospira interrogans/classification/*genetics MH - Plasmids MH - Restriction Mapping MH - Sensitivity and Specificity MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) RN - 0 (DNA, Recombinant) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 950615 DP - 1994 Dec IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 369-74 CY - CHINA IP - 4 VI - 25 JC - GEB AA - Author EM - 9508 AB - The recombinant DNA pCX7 derived from L. interrogans serovar lai strain 017 was applied for hybridization with 17 strains (8 serogroups of L. interrogans, L. biflexa strain Patoc I and Leptonema strain 3055); meanwhile 15 restriction endonucleases were used for analysis of the restriction enzyme map of pCX7. The result showed that the recombinant DNA probe is specific to species L. interrogans and its homology with DNA from different leptospires. A restriction enzyme map of pCX7 was constructed. Unique site for Bgl II and 3 sites for Bst BI were located within the cloned fragment (1.7 kb). PMID- 7744375 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1994 Dec;25(4):369-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 95247516 AU - Heath SE AU - Johnson R TI - Leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Human MH - Leptospira/immunology MH - *Leptospirosis/diagnosis/epidemiology/immunology/prevention & control MH - Prevalence MH - *Zoonoses RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 950526 DP - 1994 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1518-23 SB - M CY - UNITED STATES IP - 11 VI - 205 JC - HAV EM - 9508 AD - Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907-1249. RF - 12 PMID- 7730115 SO - J Am Vet Med Assoc 1994 Dec 1;205(11):1518-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 95235006 AU - Dai B AU - Xiao J AU - Shen C TI - Identification of pathogenic leptospires by recombinant DNA probes. LA - Eng MH - Blotting, Southern MH - DNA Probes MH - DNA, Bacterial/*analysis MH - DNA, Recombinant MH - Genomic Library MH - Human MH - Leptospira interrogans/genetics/*isolation & purification MH - Leptospirosis/diagnosis/*microbiology MH - Support, Non-U.S. Gov't RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) RN - 0 (DNA, Recombinant) PT - JOURNAL ARTICLE DA - 950524 DP - 1994 Dec IS - 1001-9294 TA - Chin Med Sci J PG - 209-14 CY - CHINA IP - 4 VI - 9 JC - A8E AA - Author EM - 9507 AB - Early diagnosis of leptospirosis of pulmonary diffuse hemorrhage type (PDH) is of crucial importance in saving patients. To develop a sensitive and specific method for diagnosis, a genomic library of the main pathogen of PDH, L. interrogans serovar lai strain 017, was constructed with the plasmid vector pUC9. Recombinant plasmids which have homologous fragments of pathogenic leptospires were screened from the bank. A recombinant plasmid, designated pCX7, could detect 1.7 kb fragment of strain 017, 9.0 kb of strain 601 and 30.0 kb of strain Hebdomadis, respectively, without cross hybridization with nonpathogenic leptospires such as L. biflexa strain Patoc I and Leptonema illini. The recombinant plasmid pCX7 could detect pathogenic leptospires which are the main pathogens endemic to Sichuan Province. AD - Department of Pathophysiology, West China University of Medical Sciences, Chengdu. PMID- 7718858 SO - Chin Med Sci J 1994 Dec;9(4):209-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 95397252 AU - Kramer KJ AU - Pang LW AU - Minette HP AU - Perrone JB TI - Evaluation of the quantitative buffy coat analysis (QBC) system for the detection of Leptospira in human blood. LA - Eng MH - Bacteriological Techniques MH - Blood Platelets/*microbiology MH - Hawaii MH - Human MH - Leptospira interrogans/*isolation & purification/ultrastructure MH - Leptospirosis/*diagnosis/microbiology PT - JOURNAL ARTICLE DA - 951010 DP - 1994 Dec IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 788-9 SB - M CY - THAILAND IP - 4 VI - 25 JC - UVN EM - 9512 AD - Department of Tropical Medicine and Medical Microbiology, University of Hawaii, Honolulu, USA. RO - M:MWS PMID- 7667735 LR - 960506 SO - Southeast Asian J Trop Med Public Health 1994 Dec;25(4):788-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 95263032 AU - Zhang M AU - Bao L AU - Yan R AU - Li S TI - [Transcript expression of the CPL 5x, BMD-3A, BMD-10 Interrogans leptospira] LA - Chi MH - Antigens, Bacterial/*genetics MH - English Abstract MH - *Gene Expression Regulation, Bacterial MH - *Genes, Bacterial MH - Leptospira interrogans/*genetics MH - RNA, Bacterial MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (RNA, Bacterial) PT - JOURNAL ARTICLE DA - 950615 DP - 1994 Dec IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 365-8 CY - CHINA IP - 4 VI - 25 JC - GEB AA - Author EM - 9508 AB - Total RNA of Leptospira interrogans SV Lai strain 017 was prepared by the method of Licl-Urea, and was used in dot hybridization with biotin- labelled DNA probes. The probes included BMD-3A, BMD-10, which were the leptospirial protective antigen genes, and CPL 5x, which was the genus specific gene of interrogans Leptospira. All of the three probes have shown various degrees of hybridization signs, proving that they all have transcript expression in leptospira. The transcript expression is the main way of regulating the gene expression in procaryotae, and it is significant in molecular genetics of Leptospira. The results indicate that the antigens encoded by the BMD-3A, BMD-10 may play an important role in immune reaction against leptospiral infection and provide a clue to the development of gene-engineering vaccine. The results also suggest that the antibody against the antigen encoded by CPL 5x is a useful tool in the classification of Leptospira interrogans. PMID- 7538094 CU - 95 GS - CPL 5x GS - BMD-3A GS - BMD-10 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1994 Dec;25(4):365-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 95010874 AU - Panidis D AU - Rousso D AU - Skiadopoulos S AU - Vavilis D AU - Kalogeropoulos A TI - Hypothalamic-pituitary deficiency after Weil's syndrome: a case report. LA - Eng MH - Adult MH - Case Report MH - Clomiphene/diagnostic use MH - FSH/blood MH - Gonadorelin/diagnostic use MH - Gonadotropins, Chorionic/diagnostic use MH - Human MH - Hydrocortisone/blood/therapeutic use MH - Hypogonadism/blood/drug therapy/*etiology MH - Hypothalamic Diseases/blood/drug therapy/*etiology MH - Insulin/diagnostic use MH - LH/blood MH - Male MH - Pituitary Diseases/blood/drug therapy/*etiology MH - Prolactin/blood MH - Protirelin/diagnostic use MH - Somatotropin/blood MH - Testosterone/blood/therapeutic use MH - Thyroxine/therapeutic use MH - Weil's Disease/*complications RN - 0 (Gonadotropins, Chorionic) RN - 11061-68-0 (Insulin) RN - 24305-27-9 (Protirelin) RN - 33515-09-2 (Gonadorelin) RN - 50-23-7 (Hydrocortisone) RN - 57-85-2 (Testosterone) RN - 7488-70-2 (Thyroxine) RN - 9002-62-4 (Prolactin) RN - 9002-67-9 (LH) RN - 9002-68-0 (FSH) RN - 9002-72-6 (Somatotropin) RN - 911-45-5 (Clomiphene) PT - JOURNAL ARTICLE DA - 941118 DP - 1994 Nov IS - 0015-0282 TA - Fertil Steril PG - 1077-9 SB - M CY - UNITED STATES IP - 5 VI - 62 JC - EVF AA - Author EM - 9501 AB - A case of male hypogonadism after Weil's syndrome is described. Hypogonadism was the result of complete hypothalamic-pituitary deficiency. The relationship between leptospirosis and the endocrinopathy, the incidence that leptospira attacks hypothalamic- pituitary axis, and the mechanism with which the microorganism may cause damage to the pituitary and/or the hypothalamus are discussed. AD - Third Department of Obstetrics and Gynecology, Aristotelian University of Thessaloniki, Greece. PMID- 7926123 SO - Fertil Steril 1994 Nov;62(5):1077-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 95202097 AU - Bernasovskaia EP AU - Kondratenko VN AU - Mel'nitskaia EV TI - [The connection of the antigenic activity of Leptospira to its virulence] LA - Rus MH - Animal MH - Antibodies, Bacterial/blood MH - Antigenic Variation MH - Antigens, Bacterial/analysis/*toxicity MH - Comparative Study MH - Disease Reservoirs MH - English Abstract MH - Guinea Pigs MH - Human MH - Kidney/microbiology MH - Leptospira interrogans/classification/*immunology/isolation & purification/*pathogenicity MH - Rats MH - Serotyping MH - Ukraine MH - Virulence/immunology MH - Weil's Disease/immunology/microbiology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 950425 DP - 1994 Nov-Dec IS - 0201-8462 TA - Mikrobiol Z PG - 46-50 CY - UKRAINE IP - 6 VI - 56 JC - BX2 AA - Author EM - 9506 AB - Virulence of Leptospira cultures isolated in leptospirosis centres of different regions of Ukraine has been studied. It is shown that certain strains of leptospiras with high virulence several times exceed in their antigenic activity the standard strains and their introduction into the set of strains for the reaction of microagglutination and use for making diagnostic and, probably, prophylactic preparations are promising. PMID- 7894728 TT - Sviaz' antigennoi aktivnosti leptospir s ikh virulentnost'iu. EA - A SO - Mikrobiol Z 1994 Nov-Dec;56(6):46-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 95185235 AU - Volina EG AU - Chandra DS AU - Kiktenko VS AU - Levina LF AU - Sarukhanova LE TI - [Leptospirosis in Bangladesh] LA - Rus MH - Animal MH - Antibodies, Bacterial/blood MH - Bangladesh/epidemiology MH - Cattle MH - Cattle Diseases/epidemiology/etiology/immunology MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology/etiology/immunology/veterinary MH - Seroepidemiologic Methods RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950403 DP - 1994 Nov-Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 60-1 SB - M CY - RUSSIA IP - 6 JC - Y9O EM - 9506 PMID- 7879542 TT - Leptospiroz v Bangladesh. SO - Zh Mikrobiol Epidemiol Immunobiol 1994 Nov-Dec;(6):60-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 95245896 AU - Ellis WA TI - Leptospirosis as a cause of reproductive failure. LA - Eng MH - Abortion, Veterinary/*microbiology/physiopathology MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology/physiopathology MH - Female MH - Fetal Death/microbiology/physiopathology/veterinary MH - Goat Diseases/*microbiology/physiopathology MH - Goats MH - Leptospirosis/complications/physiopathology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/physiopathology/*veterinary MH - Sheep MH - Sheep Diseases/*microbiology/physiopathology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 950601 DP - 1994 Nov IS - 0749-0720 TA - Vet Clin North Am Food Anim Pract PG - 463-78 SB - M CY - UNITED STATES IP - 3 VI - 10 JC - CFP AA - Author EM - 9508 AB - Leptospirosis is a zoonotic disease caused by members of the genus Leptospira. Veterinarians' perceptions of leptospirosis as a disease of domestic animals has undergone considerable modification in the past decade or so because they have increasingly appreciated the role of the host-maintained leptospires as causes of reproductive wastage in their respective host species kept under modern intensive management systems. AD - Veterinary Sciences Division, Department of Agriculture, Belfast, Northern Ireland. RF - 70 PMID- 7728630 SO - Vet Clin North Am Food Anim Pract 1994 Nov;10(3):463-78 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 95091346 AU - White WB AU - Whipple DL AU - Stabel JR AU - Bolin CA TI - Comparison of cellular and extracellular proteins expressed by various isolates of Mycobacterium paratuberculosis and other mycobacterial species. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Bacterial Proteins/*analysis MH - Blotting, Western MH - Cattle MH - Comparative Study MH - Electrophoresis, Gel, Two-Dimensional MH - Human MH - Mycobacterium/*chemistry MH - Mycobacterium paratuberculosis/*chemistry RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE DA - 950119 DP - 1994 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1399-405 SB - M CY - UNITED STATES IP - 10 VI - 55 JC - 40C AA - Author EM - 9503 AB - Protein expression profiles of 10 isolates of Mycobacterium paratuberculosis, M avium 18 (formerly M paratuberculosis 18), and 1 isolate each of M avium serotype 2, M avium serotype 8, and M bovis BCG were examined. Protein expression profiles of M paratuberculosis and M avium were similar. However, two-dimensional gel analysis of [35S]methionine-labeled cellular proteins resolved 4 proteins, with molecular mass of 28,000, 32,000, 32,000, and 42,000 daltons, which were expressed in greater amounts in M paratuberculosis than in M avium. Two proteins, with molecular mass of 43,000 and 60,000 daltons, were identified, which were expressed in greater amounts in M avium than in M paratuberculosis. Immuno (western)-blot analysis, using antiserum from 2 cows clinically infected with M paratuberculosis as the primary antibodies, suggested that the 42,000-dalton protein may be specific for M paratuberculosis. Comparison of protein expression profiles may be useful as a tool for differentiating isolates of M paratuberculosis. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of [35S]methionine-labeled extracellular proteins revealed variability among the isolates. Sodium dodecyl sulfate- polyacrylamide gel electrophoresis of [35S]methionine-labeled cellular proteins divided the M paratuberculosis isolates into 2 groups on the basis of a difference in the amount of expression of a 28,000-dalton protein. This information may be useful in epidemiologic studies. AD - Leptospirosis/Mycobacteriosis Research Unit, National Animal Disease Center, USDA, Ames, IA 50010. PMID- 7998697 SO - Am J Vet Res 1994 Oct;55(10):1399-405 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 95087000 AU - Lees VW AU - Gale SP TI - Titers to Leptospira species in horses in Alberta. LA - Eng MH - Alberta MH - Animal MH - Antibodies, Bacterial/*analysis MH - Horse Diseases/*immunology MH - Horses MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Prevalence MH - Risk Factors MH - Serotyping RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950117 DP - 1994 Oct IS - 0008-5286 TA - Can Vet J PG - 636-40 SB - M CY - CANADA IP - 10 VI - 35 JC - CLS AA - Author EM - 9503 AB - Sera from horses in Alberta, submitted to Agriculture and Agri-Food Canada for routine testing for equine infectious anemia from January 1987 to June 1989, were tested for antibody against 13 serovars of pathogenic Leptospira spp., using the microscopic agglutination test. The purpose of the study was to investigate the prevalence of serum titers to those serovars in horses in Alberta, and to analyze the associated risk factors. Descriptive statistics were compiled and logistic regressions were computed. Titers to L. interrogans serovars icterohaemorrhagiae, bratislava, copenhageni, and autumnalis were common (94.6%, 56.6%, 46.5%, and 43.5%, respectively). The prevalence of titers to other serovars ranged from 0.8% to 27.2%. Age was almost always significantly associated with the presence of titers. In general, the chances of being seropositive rose by approximately 10% with each year of life. Horses managed individually (eg, track horses) were approximately half as likely to be seropositive as were horses managed in groups (eg, rodeo horses). AD - Agriculture and Agri-Food Canada, Animal Diseases Research Institute, Lethbridge, Alberta. PMID- 7994706 SO - Can Vet J 1994 Oct;35(10):636-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 95080929 AU - Fuortes L AU - Nettleman M TI - Leptospirosis: a consequence of the Iowa flood. LA - Eng MH - Adult MH - Animal MH - Case Report MH - Diagnosis, Differential MH - Female MH - Human MH - Iowa MH - Leptospirosis/*transmission MH - Male MH - *Natural Disasters MH - Risk Factors MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 950112 DP - 1994 Oct IS - 0746-8709 TA - Iowa Med PG - 449-50 CY - UNITED STATES IP - 10 VI - 84 JC - GWQ EM - 9503 AD - University of Iowa Occupational Health Service. PMID- 7989184 SO - Iowa Med 1994 Oct;84(10):449-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 protein link] [6 nucleotide links] [129 medline neighbors] UI - 95014031 AU - Ralph D AU - McClelland M TI - Phylogenetic evidence for horizontal transfer of an intervening sequence between species in a spirochete genus. LA - Eng MH - Amino Acid Sequence MH - Base Sequence MH - Comparative Study MH - DNA Insertion Elements/genetics MH - DNA, Bacterial/*genetics MH - *DNA, Recombinant MH - Genes, Bacterial/genetics MH - Introns/*genetics MH - Leptospira/classification/*genetics MH - Molecular Sequence Data MH - Phylogeny MH - Polymorphism, Restriction Fragment Length MH - RNA, Ribosomal, 16S/*genetics MH - Sequence Homology, Amino Acid MH - Species Specificity MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. RN - 0 (DNA Insertion Elements) RN - 0 (DNA, Bacterial) RN - 0 (DNA, Recombinant) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE ID - AI34829/AI/NIAID ID - HG00456/HG/NCHGR ID - NS33377/NS/NINDS ID - + DA - 941028 DP - 1994 Oct IS - 0021-9193 TA - J Bacteriol PG - 5982-7 SB - M CY - UNITED STATES IP - 19 VI - 176 JC - HH3 AA - Author EM - 9501 AB - The 23S rRNA genes (rrl genes) of some strains of certain species of the spirochete genus Leptospira carry an intervening sequence (IVS) of 485 to 759 bases flanked by terminal inverted repeat and encoding an open reading frame for a putative protein of over 120 amino acids. The structure and the sporadic distribution of the IVS suggest that it might be a mobile element that can be horizontally transferred within or between species. Phylogenetic hypotheses based on the sequences for six IVS open reading frames from various species were compared with hypotheses constructed by using DNA sequences from the 16S rRNA gene (rrs), which is not closely linked to rrl in this genus. The predicted phylogenies for the IVS and rrs differed in a major respect: one strain that claded with L. weillii in the tree based on the rrs data claded with L. noguchi in the tree based on the IVS data. Neither set of data supported a tree in which this strain was constrained to be in the same clade as was supported by the other set of data. This result indicates a probable horizontal transfer of the IVS from a recent ancestor of L. noguchi to a recent ancestor of one of the L. weillii strains. This observation is the first indication of horizontal transfer of elements encoded on the chromosomes of spirochetes. AD - California Institute of Biological Research, La Jolla 92037. RO - M:CNR PMID- 7928959 LR - 950221 CU - 95 SI - GENBANK/U12669 SI - GENBANK/U12671 SI - GENBANK/U12672 SI - GENBANK/U12673 SI - GENBANK/U12674 SI - GENBANK/U12676 SO - J Bacteriol 1994 Oct;176(19):5982-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 95163072 AU - Yang W AU - Pang J AU - Li C TI - [An investigation on the distribution of leptospirae interrogans in water and soil in southwest of Yunnan Province] LA - Chi MH - China MH - English Abstract MH - Leptospira interrogans/classification/*isolation & purification MH - *Soil Microbiology MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 950322 DP - 1994 Oct IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 289-91 CY - CHINA IP - 5 VI - 15 JC - CQG AA - Author EM - 9505 AB - The conservation of pathogenic leptospirae in water and soil is one of the important problems of geography-epidemiological survey of leptospirosis. We have conducted this investigation by using of filtration-culture isolation method in five counties in the west and southwest of Yunnan during 1988-1992. The results showed that the isolates from samples of water and soil collected between July and September in Menglian and Huaping county were leptospirae biflexa while in the samples of water and soil collected between November and December in three counties, 8 strains of L. interrogans were isolated from the samples of Gengma and Baoshan county. The total positive rate was 3.31% (8/242). The positive rate of water and soil was 2.14% (3/140) and 4.9% (5/102) respectively. Strains obtained in this investigation belong to six serogroups: Icterohaemorrhagiae and Pyrogenes in 2 respectively. Canicola, Grippotyphosa, Sejroe and Australis in 1 respectively. These serogroups of leptospirae obtained from water and soil were corresponded with the serogroups obtained from the patients and animals with leptospirosis in local area. This survey provided new data for expounding the structure of the focus of leptospirosis. AD - Yunnan provincial institute of epidemic disease control and research, Dali. PMID- 7859262 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1994 Oct;15(5):289-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 95216416 AU - Perea A AU - Garcia R AU - Maldonado A AU - Tarradas MC AU - Luque I AU - Astorga R AU - Arenas A TI - Prevalence of antibodies to different Leptospira interrogans serovars in pigs on large farms. LA - Eng MH - Animal MH - Antibodies, Bacterial/*blood MH - Female MH - Leptospira interrogans/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Prevalence MH - Seroepidemiologic Methods MH - Spain/epidemiology MH - Swine MH - Swine Diseases/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950504 DP - 1994 Oct IS - 0931-1793 TA - Zentralbl Veterinarmed [B] PG - 512-6 CY - GERMANY IP - 7-8 VI - 41 JC - Y72 AA - Author EM - 9507 AB - A seroepidemiological survey was carried out in the province of Badajoz (south-western Spain) in order to determine the presence and spread of Leptospira interrogans. The 521 sera tested were drawn from breeding sows on 28 large farms (15 with fewer than 60 and 13 with over 60 breeders). Immunological testing was performed using the Martin-Pettit micro-agglutination technique. Pigs with titres equal to or greater than 1:100 were considered positive. Haemolysed and/or contaminated test sera were reprocessed following filter-paper treatment. A total of 10.56% of pigs tested proved positive, 39.28% of farms being affected. The following L. interrogans serovars were detected: pomona (6.53%), castellonis (1.15%), sejroe (1.15%), grippotyphosa (0.96%), australis (0.38%), hebdomadis (0.19%) and icterohaemorrhagiae (0.19%). AD - Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Cordoba, Spain. PMID- 7701864 SO - Zentralbl Veterinarmed [B] 1994 Oct;41(7-8):512-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [35 medline neighbors] UI - 95036568 AU - Afzal M AU - Sakkir M TI - Survey of antibodies against various infectious disease agents in racing camels in Abu Dhabi, United Arab Emirates. LA - Eng MH - Animal MH - Antibodies/*blood MH - Aspergillosis/epidemiology/veterinary MH - Brucella abortus/immunology MH - Brucellosis/epidemiology/veterinary MH - *Camels MH - Communicable Diseases/epidemiology/*veterinary MH - Echinococcosis/epidemiology/veterinary MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/veterinary MH - Parainfluenza Virus 3, Human/immunology MH - Paramyxoviridae Infections/epidemiology/veterinary MH - Prevalence MH - Q Fever/epidemiology/veterinary MH - Seroepidemiologic Methods MH - Sports MH - Toxoplasmosis, Animal/epidemiology MH - United Arab Emirates/epidemiology RN - 0 (Antibodies) PT - JOURNAL ARTICLE DA - 941125 DP - 1994 Sep IS - 0253-1933 TA - Rev Sci Tech PG - 787-92 SB - M CY - FRANCE IP - 3 VI - 13 JC - A9R AA - Author EM - 9502 AB - Prevalence of antibodies against some important disease agents in sera from racing camels in Abu Dhabi (United Arab Emirates) is reported. Antibodies against Brucella abortus were detected in 1.5% of racing camels, but only 0.76% had titres sufficient for the animals to be considered infected. The complement fixation test revealed antibodies against Coxiella burnetii (causative agent of Q fever) in 7.9% of camels (with a geometrical mean titre of 13) and against parainfluenza virus type 3 in 5.6% of camels (with a geometrical mean titre of 20). Serological evidence did not show the presence of Aspergillus spp., while antibodies against Leptospira interrogans were seen in 4.1% of camels. Antibodies against Echinococcus polymorphus were observed in 2.6% of the animals, while a large number of racing camels (30.9% and 36.4%) possessed antibodies against Toxoplasma gondii, as determined by direct agglutination and indirect haemagglutination, respectively. AD - Animal Sciences Institute, National Agricultural Research Centre, Pakistan Agricultural Research Council, Islamabad. PMID- 7949353 CU - 96 SO - Rev Sci Tech 1994 Sep;13(3):787-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 95203838 AU - Shen C AU - Baomin D TI - [Characterization of leptospiral DNA by southern hybridization serovar lai recombinant probe pCX7] LA - Chi MH - Blotting, Southern MH - DNA Probes MH - DNA, Bacterial/*analysis MH - DNA, Recombinant MH - English Abstract MH - Genomic Library MH - Leptospira/*classification/isolation & purification MH - Leptospira interrogans/genetics MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) RN - 0 (DNA, Recombinant) PT - JOURNAL ARTICLE DA - 950427 DP - 1994 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 248-52 CY - CHINA IP - 3 VI - 25 JC - GEB AA - Author EM - 9506 AB - The recombinant probe pCX7, derived from genomic library of serovar lai strain 017, was applied for the characterization of DNA from 20 strains of leptospires in different genus species, sero-groups and serovars by southern hybridization. The probe, specific to partial species L. interrogans, did not hybridized with DNA of L. biflexa strain Patoc I and L. illini strain 3055, neither with DNA of serovars javanica, manhao 2 and ranarum which had shown very weak virulence, but hybridized with DNA of the other 15 strains of L. interrogans in 8 serogroups. It was easy to distinguish the banding patterns, since the pCX7 probe hybridized with a limited number of DNA fragments. Different leptospires showed different banding patterns. A few differences between strain 017 (strain of strong virulence) and strain 601 (strain of weak virulence) of serovar Lai were observed although their hybridization banding patterns were very similar. Differences in hybridization signals in combination with the banding pattern appear to provide good characteristics for identification of leptospiral serogroups and serovars, even strains. The result indicated that southern hybridization with the probe pCX7 might provide good tools for identification of leptospira. PMID- 7896238 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1994 Sep;25(3):248-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 95203837 AU - Wu W AU - Dai B TI - [Analysis on early serum samples from patients with leptospirosis by polymerase chain reaction] LA - Chi MH - English Abstract MH - *Genes, Bacterial MH - Human MH - Leptospira interrogans/*genetics MH - Polymerase Chain Reaction MH - RNA, Ribosomal, 16S/genetics MH - Support, Non-U.S. Gov't MH - Weil's Disease/*diagnosis/genetics RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 950427 DP - 1994 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 245-7 CY - CHINA IP - 3 VI - 25 JC - GEB AA - Author EM - 9506 AB - Fifty-five serum samples from patients with leptospirosis treated by the method of high SiO2 concentration salt solution absorption were analysed with the variable sequences of the 16S rRNA genes of Leptospria interrogans as primers. It is shown that the 16S rRNA gene primer is useful for the clinical detection and the epidemic investigation of leptospirosis, and the detecting effect by PCR is superior to that by the blood culture and MAT (P < 0.01). PMID- 7896237 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1994 Sep;25(3):245-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 95135620 AU - Mel'nitskaia EV TI - [The use of an indirect immunoenzyme method in the diagnosis of leptospirosis] LA - Rus MH - Antibodies, Bacterial/*blood MH - Antibody Specificity MH - Antigens, Bacterial/isolation & purification MH - Comparative Study MH - English Abstract MH - Human MH - Immunoenzyme Techniques MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/*diagnosis MH - Sensitivity and Specificity MH - Ultrasonics MH - Weil's Disease/*diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 950302 DP - 1994 Sep-Oct IS - 0201-8462 TA - Mikrobiol Z PG - 24-8 CY - UKRAINE IP - 5 VI - 56 JC - BX2 AA - Author EM - 9505 AB - Sensitivity and specificity of indirect immunoenzyme method for determining antileptospirosis antibodies have been studied. Supersound antigenic preparations are used as antigens. Determination of genus- specific antibodies and antibodies of more narrow specificity including serogroup specific ones is possible in the elaborated test. A spectrum of revealed serogroup specific antibodies expends in patients with leptospirosis when using polyvalent antigenic preparations. PMID- 7834100 TT - Ispol'zovanie nepriamogo immunofermentnogo metoda pri diagnostike leptospiroza. EA - A SO - Mikrobiol Z 1994 Sep-Oct;56(5):24-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 95118248 AU - Smith CR AU - Ketterer PJ AU - McGowan MR AU - Corney BG TI - A review of laboratory techniques and their use in the diagnosis of Leptospira interrogans serovar hardjo infection in cattle. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Bacteriological Techniques/veterinary MH - Cattle MH - Cattle Diseases/*diagnosis/immunology/microbiology MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Female MH - *Leptospira interrogans MH - Leptospirosis/diagnosis/immunology/microbiology/*veterinary MH - Male PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 950209 DP - 1994 Sep IS - 0005-0423 TA - Aust Vet J PG - 290-4 SB - M CY - AUSTRALIA IP - 9 VI - 71 JC - 9IE AA - Author EM - 9504 AB - This paper reviews the laboratory diagnosis of Leptospira hardjo infection in cattle. Two genotypes of L hardjo, Hardjoprajitno and Hardjobovis, have been identified in cattle, but only Hardjobovis has been isolated in Australia. There are problems with diagnosis and control of bovine leptospirosis. Infection is usually subclinical and the serological titres vary greatly in peak and duration. Leptospires may be excreted in urine for up to 18 months. Low microscopic agglutination test titres may be significant in unvaccinated herds as indicators of endemic infection. Vaccines differ in their composition, and their efficacy is difficult to evaluate. The serological response after vaccination is difficult to differentiate from the response after infection. Pregnant cows that become infected may abort, but this is usually after the serological response has peaked. Therefore, paired serum samples are of little use in diagnosing abortion caused by L hardjo. Fluorescent antibody techniques are more sensitive than dark field microscopy for detection of leptospires in urine and tissue samples. Techniques for culture have improved but are still difficult to perform and take 3 months or longer for results to be known. DNA probes and polymerase chain reaction tests are very sensitive and specific, quick to perform, and can be used on fluid and tissue samples. AD - Department of Farm Animal Medicine and Production, University of Queensland, Dayboro. RF - 88 PMID- 7818437 SO - Aust Vet J 1994 Sep;71(9):290-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 95100667 AU - Gerritsen MJ AU - Koopmans MJ AU - Peterse D AU - Olyhoek T TI - Sheep as maintenance host for Leptospira interrogans serovar hardjo subtype hardjobovis. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Base Sequence MH - Cattle MH - *Cattle Diseases MH - DNA Primers MH - Enzyme-Linked Immunosorbent Assay MH - *Leptospira interrogans/genetics/isolation & purification MH - Molecular Sequence Data MH - Polymerase Chain Reaction/methods/veterinary MH - Sensitivity and Specificity MH - Sheep/*microbiology MH - *Sheep Diseases MH - Support, Non-U.S. Gov't MH - Urine/microbiology MH - Weil's Disease/transmission/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (DNA Primers) PT - JOURNAL ARTICLE DA - 950125 DP - 1994 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1232-7 SB - M CY - UNITED STATES IP - 9 VI - 55 JC - 40C AA - Author EM - 9503 AB - Transmission of Leptospira interrogans serovar hardjo subtype hardjobovis from naturally infected sheep to uninfected sheep and calves was studied. A microscopic agglutination test and ELISA were used to determine specific antibody responses in serum. Polymerase chain reaction was used to detect bacterial shedding in urine. Six sheep were derived from a dairy farm where cows were infected with L hardjobovis. Three of these sheep were seropositive for L hardjobovis, and 1 also shed leptospires in the urine. The other 2 sheep shed leptospires in the urine 7 days after the first observation date. The 6 sheep were placed on an isolated pasture together with a second group of 6 noninfected sheep. During the observation period of 140 days, 1 sheep of the second group became infected with L hardjobovis. On 5 consecutive days, a urine mixture from the 4 infected sheep was sprayed on the heads of 4 noninfected calves. Within 56 days, all calves that had been sprayed with urine shed L hardjobovis in the urine and became seropositive for L hardjobovis. AD - Department of Bacteriology, Central Veterinary Institute, Lelystad, The Netherlands. PMID- 7802389 SO - Am J Vet Res 1994 Sep;55(9):1232-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 95100664 AU - Ji B AU - Thomas CB AU - Collins MT TI - Evaluation of an enzyme-linked immunosorbent assay that uses the 41-kd flagellin as the antigen for detection of antibodies to Borrelia burgdorferi in cattle. LA - Eng MH - Animal MH - Antibodies, Bacterial/*blood MH - Antibody Specificity MH - Antigens, Bacterial/*immunology MH - Borrelia/immunology MH - Borrelia burgdorferi/*immunology MH - Cattle MH - *Cattle Diseases MH - Comparative Study MH - Cross Reactions MH - Enzyme-Linked Immunosorbent Assay/methods/*veterinary MH - Flagellin/*immunology MH - Immunoblotting MH - Lyme Disease/diagnosis/*veterinary MH - Microscopy, Immunoelectron MH - Molecular Weight MH - Sensitivity and Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 12777-81-0 (Flagellin) PT - JOURNAL ARTICLE DA - 950125 DP - 1994 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1213-9 SB - M CY - UNITED STATES IP - 9 VI - 55 JC - 40C AA - Author EM - 9503 AB - An ELISA was developed to detect antibodies to the 41-kd flagellin (P41) of Borrelia burgdorferi in serum obtained from cattle. Absorption studies, immunoblot analysis, immunoelectron microscopy, and correlation of results of the P41-ELISA and the P39-ELISA as well as measurement of the antibody to P41 in calves challenge-exposed with Borrelia theileri were used to assess the specificity of the P41-ELISA. Antigens derived from Escherichia coli, Leptospira interrogans serovar hardjo, and B burgdorferi were used for absorption studies and immunoblot analysis. Antibodies to P41 of B burgdorferi cross-reacted with antigens of E coli, but were not cross-reactive with L hardjo. A value 3 SD higher than the mean of the negative-control population of cattle was defined as the minimum value (cutoff value) for a positive result by the P41-ELISA. Use of this value for classification of test results reduced the predicted rate of false-positive results attributable to E coli cross-reactivity to 1%. Immunoblot analysis revealed that test-positive serum from cattle reacted mainly with 41-, 39-, 34-, and 31-kd proteins of B burgdorferi, as well as several smaller proteins. Immunoelectron microscopy revealed that serum from cattle that was test-positive by the P41-ELISA bound to the flagellin and outer membrane of B burgdorferi. Results of absorption studies, immunoblot analysis, and immunoelectron microscopy were correlated and indicated that serum from cattle that was test-positive by P41-ELISA had stronger reactivity to B burgdorferi antigens than to antigens of E coli or L hardjo.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706-1102. PMID- 7802386 SO - Am J Vet Res 1994 Sep;55(9):1213-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [96 medline neighbors] UI - 96015880 AU - da Silva MV AU - Nakamura PM AU - Camargo ED AU - Batista L AU - Vaz AJ AU - Brandao AP AU - Ferreira AW TI - Dot-ELISA-IgM in saliva for the diagnosis of human leptospirosis using polyester fabric-resin as support (preliminary report). LA - Eng MH - Antibodies, Anti-Idiotypic/*analysis MH - Enzyme-Linked Immunosorbent Assay/*methods MH - Human MH - IgM/*analysis MH - Resins, Synthetic MH - Saliva/*chemistry MH - Weil's Disease/*diagnosis RN - 0 (Antibodies, Anti-Idiotypic) RN - 0 (IgM) RN - 0 (Resins, Synthetic) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE DA - 951027 DP - 1994 Sep-Oct IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 475-8 CY - BRAZIL IP - 5 VI - 36 JC - S9D AA - Author EM - 9601 AB - In order to improve the diagnosis of human leptospirosis, we standardized the dot-ELISA for the search of specific IgM antibodies in saliva. Saliva and serum samples were collected simultaneously from 20 patients with the icterohemorrhagic form of the disease, from 10 patients with other pathologies and from 5 negative controls. Leptospires of serovars icterohaemorrhagiae, canicola, hebdomadis, brasiliensis and cynopteri grown in EMJH medium and mixed together in equal volumes, were used as antigen at individual protein concentration of 0.2 micrograms/microliters. In the solid phase of the test we used polyester fabric impregnated with N-methylolacrylamide resin. The antigen volume for each test was 1 microliter, the saliva volume was 8 microliters, and the volume of peroxidase-labelled anti-human IgM conjugate was 30 microliters. A visual reading was taken after development in freshly prepared chromogen solution. In contrast to the classic nitrocellulose membrane support, the fabric support is easy to obtain and to handle. Saliva can be collected directly onto the support, a fact that facilitates the method and reduces the expenses and risks related to blood processing. AD - Instituto Adolfo Lutz, Sao Paulo, Brasil. PMID- 7569617 SO - Rev Inst Med Trop Sao Paulo 1994 Sep-Oct;36(5):475-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 94352658 AU - Kecskes B TI - [The role of the kallikrein-kinin system in the pathogenesis of leptospirosis] LA - Hun MH - Adult MH - Animal MH - Disease Models, Animal MH - English Abstract MH - Female MH - Guinea Pigs MH - Human MH - Kallikrein/metabolism MH - Kallikrein-Kinin System/*physiology MH - Kinins/metabolism MH - Leptospira/classification MH - Leptospirosis/*etiology/metabolism/microbiology/pathology MH - Male MH - Prekallikrein/metabolism RN - EC 3.4.21.34 (Kallikrein) RN - 0 (Kinins) RN - 9055-02-1 (Prekallikrein) PT - JOURNAL ARTICLE DA - 940928 DP - 1994 Aug 28 IS - 0030-6002 TA - Orv Hetil PG - 1913-7 CY - HUNGARY IP - 35 VI - 135 JC - OL8 AA - Author EM - 9412 AB - The author studied the clinical and biochemical characteristic of leptospirosis in 101 patients and the changes of the components of the kallikrein-kinin system during the dynamics of the disease and the valuation of its prognosticated importance. In 26 patients she determined the level of prekallikrein and kallikrein in serum. Furthermore author measured level of components of kallikrein-kinin system in 16 guinea-pigs, infected with different virulence L. icterohaemorrhagie. She determined the serum prekallikrein and kallikrein in 20 control persons and 10 healthy guinea-pigs. At the peak of the disease the decreased level of prekallikrein with increased kallikrein activity at the same time was evaluated as in one respect its reduced synthesis in the liver, on the other hand by change of proenzyme into active form. In the phase of reconvalescence the normalization of the level of prekallikrein was missing. In these patients who got over the illness of icteric leptospirosis with acute renal failure at the controlled examination increased prekallikrein were found that supposed the absence of normalization of metabolism of kinins. On the basis of these data and experimental results author can establish that the components of kallikrein-kinin system in the high degree reflect the functional condition of liver and kidney at different phase of the disease. AD - Pavlov Orvostudomanyi Egyetem, Szentpetervar, Fertozo Betegsegek Tanszeke. PMID- 8072763 TT - A kallikrein-kinin rendszer jelentosege a leptospirosis patogeneziseben. EA - A SO - Orv Hetil 1994 Aug 28;135(35):1913-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 95081373 AU - Perolat P AU - Merien F AU - Ellis WA AU - Baranton G TI - Characterization of Leptospira isolates from serovar hardjo by ribotyping, arbitrarily primed PCR, and mapped restriction site polymorphisms. LA - Eng MH - Animal MH - *Bacterial Typing Techniques MH - Base Sequence MH - Cattle MH - Chromosome Mapping MH - Comparative Study MH - DNA Fingerprinting MH - DNA, Ribosomal/*genetics MH - Genes, Bacterial/genetics MH - Horses MH - Human MH - Leptospira/*classification/genetics MH - Leptospirosis/microbiology MH - Molecular Sequence Data MH - Polymerase Chain Reaction/*methods MH - *Polymorphism, Restriction Fragment Length MH - RNA, Ribosomal, 16S/genetics MH - RNA, Ribosomal, 23S/genetics MH - Serotyping MH - Sheep MH - Support, Non-U.S. Gov't RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Ribosomal, 16S) RN - 0 (RNA, Ribosomal, 23S) PT - JOURNAL ARTICLE DA - 950109 DP - 1994 Aug IS - 0095-1137 TA - J Clin Microbiol PG - 1949-57 SB - M CY - UNITED STATES IP - 8 VI - 32 JC - HSH AA - Author EM - 9503 AB - Leptospira serovar hardjo isolates of the hardjoprajitno and hardjobovis genotypes were characterized by ribotyping, arbitrarily primed PCR (AP-PCR) fingerprinting, and the study of mapped restriction site polymorphisms (MRSPs) in rrs and rrl genes. After restriction of chromosomal DNA with BglII, EcoRI, or HindIII, each genotype was individualized with a distinct ribotype. The fingerprints produced by AP-PCR with seven primers clearly separated the two groups; primers KF and RSP produced species-specific products which assigned hardjoprajitno and hardjobovis isolates to the species L. interrogans sensu stricto and L. borgpetersenii, respectively. Furthermore, AP-PCR fingerprints gave evidence of a considerable genomic heterogeneity at the strain level among the hardjobovis group. Conversely, the hardjoprajitno group was homogeneous. MRSP profiles in ribosomal genes indicated that hardjoprajitno and hardjobovis isolates belonged to L. interrogans MRSP group B and L. borgpetersenii group C, respectively. AP-PCR and determination of MRSPs in ribosomal genes proved to be quick and reliable methods for typing Leptospira strains and for studying intraspecific population structures. AD - Laboratoire des Leptospires, Institut Pasteur, Noumea, New Caledonia. PMID- 7989548 SO - J Clin Microbiol 1994 Aug;32(8):1949-57 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 95081362 AU - Bal AE AU - Gravekamp C AU - Hartskeerl RA AU - De Meza-Brewster J AU - Korver H AU - Terpstra WJ TI - Detection of leptospires in urine by PCR for early diagnosis of leptospirosis. LA - Eng MH - Acute Disease MH - Antibodies, Bacterial/blood MH - Base Sequence MH - Comparative Study MH - Convalescence MH - Human MH - Leptospira/growth & development MH - Leptospirosis/blood/*diagnosis/*urine MH - Molecular Sequence Data MH - Polymerase Chain Reaction/*methods MH - Support, Non-U.S. Gov't MH - Time Factors MH - Urine/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950109 DP - 1994 Aug IS - 0095-1137 TA - J Clin Microbiol PG - 1894-8 SB - M CY - UNITED STATES IP - 8 VI - 32 JC - HSH AA - Author EM - 9503 AB - We tested urine samples from patients at different stages of current leptospirosis and thereafter to determine whether use of the PCR for detection of leptospires in urine can be a valuable alternative to culturing. The procedure of DNA extraction and subsequent PCR applied to 15 freshly voided urine samples proved to be twice as sensitive as culturing. Overall, we were able to detect leptospires in approximately 90% (26 of 29) of the urine samples. Urine and serum samples were obtained from seven patients, before the eighth day of illness. Although it is generally assumed that leptospiruria starts approximately in the second week of illness, we were able to detect leptospires in all of these early urine samples. In contrast, only two of seven corresponding serum samples gave positive PCR results, which suggests that PCR analysis of urine can be more successful for early diagnosis of leptospirosis than PCR analysis of serum. Urine samples from six patients who had been treated with antibiotics at the time of illness were positive by PCR, implying that the patients were still shedding leptospires in their urine despite treatment. Some of these samples were even taken years after the infection, indicating that shedding of leptospires in urine may last much longer than is generally assumed. We conclude that detection of leptospires in urine with PCR is a promising approach for early diagnosis of leptospirosis and may also be useful in studying long-term shedding. AD - Department of Biomedical Research, Royal Tropical Institute, Amsterdam, The Netherlands. PMID- 7989538 SO - J Clin Microbiol 1994 Aug;32(8):1894-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 95022518 AU - Williams N TI - Zoonotic infections: the animal connection. LA - Eng MH - Agricultural Workers' Diseases/*epidemiology/prevention & control MH - Animal MH - Brucellosis/epidemiology/prevention & control MH - Human MH - Leptospirosis/epidemiology/prevention & control MH - Occupational Diseases/*epidemiology/prevention & control MH - Ornithosis/epidemiology/prevention & control MH - Risk Factors MH - Zoonoses/*epidemiology/prevention & control PT - JOURNAL ARTICLE DA - 941103 DP - 1994 Aug IS - 0029-7917 TA - Occup Health (Lond) PG - 278-80 SB - N CY - ENGLAND IP - 8 VI - 46 JC - ODB EM - 9501 PMID- 7936540 LI - N SO - Occup Health (Lond) 1994 Aug;46(8):278-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [6 nucleotide links] [203 medline neighbors] UI - 95171241 AU - Wagenaar JA AU - Segers RP AU - Van der Zeijst BA TI - Rapid and specific detection of pathogenic Leptospira species by amplification of ribosomal sequences. LA - Eng MH - Animal MH - Bacterial Typing Techniques MH - Bacteriuria/diagnosis/microbiology/veterinary MH - Base Sequence MH - Cattle MH - Cattle Diseases/diagnosis/microbiology/urine MH - Comparative Study MH - DNA, Bacterial/*analysis MH - DNA, Ribosomal/*analysis MH - Electrophoresis, Agar Gel MH - Human MH - Leptospira/classification/genetics/*isolation & purification/pathogenicity MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Molecular Sequence Data MH - Nucleic Acid Hybridization MH - Polymerase Chain Reaction/*methods MH - RNA, Ribosomal, 16S/*genetics MH - Sensitivity and Specificity MH - Sequence Alignment MH - Sequence Homology, Nucleic Acid MH - Species Specificity MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/diagnosis/microbiology/urine MH - Virulence/genetics RN - 0 (DNA, Bacterial) RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 950327 DP - 1994 Aug IS - 1073-6085 TA - Mol Biotechnol PG - 1-14 SB - M CY - UNITED STATES IP - 1 VI - 2 JC - B97 AA - Author EM - 9506 AB - We have developed an assay for the detection of pathogenic Leptospira that is based on the polymerase chain reaction. With the combination of agarose gel electrophoresis and blotting, pathogenic Leptospira can be discriminated specifically from nonpathogenic Leptospira and other bacterial species. This method, based on the amplification of 16S ribosomal RNA sequences, is able to detect 10 leptospiral cells/mL in cattle urine samples and 100 leptospiral cells/mL in pig urine samples. Using this assay leptospires were detected in urine samples from cattle that were experimentally infected with Leptospira interrogans serovar hardjo type hardjobovis. AD - Department of Bacteriology, School of Veterinary Medicine, Utrecht University, The Netherlands. PMID- 7866864 CU - 95 SI - GENBANK/S76598 SI - GENBANK/S76602 SI - GENBANK/S76603 SI - GENBANK/S76605 SI - GENBANK/S76607 SI - GENBANK/S76609 SO - Mol Biotechnol 1994 Aug;2(1):1-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 95136319 AU - Lin T AU - Shi M AU - Long J TI - [Studies on the early serodiagnosis of leptospirosis by dot-ELISA] LA - Chi MH - Agglutination Tests MH - Comparative Study MH - Culture Media MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay/methods MH - Human MH - Leptospira/growth & development MH - Leptospirosis/*diagnosis MH - Serodiagnosis RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 950228 DP - 1994 Aug IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 223-6 CY - CHINA IP - 4 VI - 15 JC - CQG AA - Author EM - 9505 AB - Thirty serum samples of patients with early leptospirosis from whom cultures of leptospira were positive were tested by dot-enzyme linked immunosorbent assay (dot-ELISA) and microscopical agglutination test (MAT). The results showed that the positive rate of dot-ELISA (40%) was higher than that of MAT (13.3%). One-hundred and ninety-eight serum samples from patients with clinical diagnosis of early leptospirosis were tested by dot-ELISA, MAT and blood culture. The results showed that the positive rate of dot-ELISA (64.6%) was higher than that of blood culture (15.2%) and MAT (14.1%). The longer the time of the illness, the lower the positive rate of the blood culture. However, the positive rate of dot-ELISA was stable in different stages of the illness. AD - Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing. PMID- 7834707 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1994 Aug;15(4):223-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 95097525 AU - Kashiwase H AU - Ono E AU - Yanagawa R AU - Shimizu Y AU - Kida H TI - A neutral sugar is responsible for serovar specificity of the antigenic determinant of Leptospira interrogans serovar canicola. LA - Eng MH - Animal MH - Antibodies, Monoclonal MH - Antigens, Bacterial/*chemistry/immunology MH - Carbohydrates/analysis MH - Epitopes/*chemistry MH - Glycolipids/*chemistry/immunology MH - Leptospira interrogans/classification/*immunology MH - Mass Fragmentography MH - Mice/immunology MH - Oligosaccharides/chemistry/isolation & purification MH - Variation (Genetics) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Carbohydrates) RN - 0 (Epitopes) RN - 0 (Glycolipids) RN - 0 (Oligosaccharides) PT - JOURNAL ARTICLE DA - 950120 DP - 1994 Aug IS - 0047-1917 TA - Jpn J Vet Res PG - 103-8 CY - JAPAN IP - 2 VI - 42 JC - KRG AA - Author EM - 9503 AB - To provide information on the chemical structures of antigenic determinants of leptospira, glycolipids of Leptospira interrogans serovar canicola strain Hond Utrecht IV (Ut-IV) and its antigenic variant selected in the presence of a serovar-specific monoclonal antibody were compared physicochemically. Gas-liquid chromatography- mass spectrometry analysis revealed that the glycolipid of Ut-IV contained 6 neutral sugar species; rhamnose, mannose, galactose, glucose, and unknown sugars III and IV, in addition to unknown sugars I and II that had been previously reported. On the other hand, the glycolipid of the variant lacked unknown sugar III, suggesting that this sugar is responsible for the serovar-specific antigenic determinant. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. PMID- 7528287 CU - 95 SO - Jpn J Vet Res 1994 Aug;42(2):103-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 94309852 AU - Thomas MC AU - Chereshsky A AU - Manning K TI - An outbreak of leptospirosis on a single farm in east Otago. LA - Eng MH - Adolescence MH - Adult MH - Agricultural Workers' Diseases/*epidemiology MH - Case Report MH - Child MH - *Dairying MH - *Disease Outbreaks MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - New Zealand/epidemiology PT - JOURNAL ARTICLE DA - 940812 DP - 1994 Jul 27 IS - 0028-8446 TA - N Z Med J PG - 290-1 SB - M CY - NEW ZEALAND IP - 982 VI - 107 JC - OBQ AA - Author EM - 9410 AB - AIMS. To present an outbreak of leptospirosis on a dairy farm which had an unvaccinated herd. METHODS. Nine people working or living on the farm were tested for the presence of leptospira antibody by the microscopic agglutination test. Nineteen cows randomly selected, were also tested. RESULTS. Three human cases and one suspected case were detected over a one month period (December 1992-January 1993). Seventy- nine percent of the dairy herd tested had serological evidence of infection with L hardjo. CONCLUSIONS. Leptospirosis continues to be a major occupational problem in New Zealand. The importance of herd vaccination and the use of protective clothing during milking is emphasised. AD - Dunedin Hospital. PMID- 8035968 SO - N Z Med J 1994 Jul 27;107(982):290-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 96293079 AU - Muthusethupathi MA AU - Shivakumar S AU - Vijayakumar R AU - Jayakumar M TI - Renal involvement in leptospirosis--our experience in Madras City. LA - Eng MH - Adult MH - Aged MH - *Developing Countries MH - Female MH - Human MH - Incidence MH - India/epidemiology MH - Kidney Failure, Acute/epidemiology/*microbiology/therapy MH - Leptospirosis/*complications/epidemiology/therapy MH - Male MH - Middle Age MH - Risk Factors MH - Rural Population MH - Survival Rate PT - JOURNAL ARTICLE DA - 960904 DP - 1994 Jul-Sep IS - 0022-3859 TA - J Postgrad Med PG - 127-31 CY - INDIA IP - 3 VI - 40 JC - JS7 EM - 9611 AD - Department of Nephrology, Government General Hospital, Madras. PMID- 8699377 SO - J Postgrad Med 1994 Jul-Sep;40(3):127-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 95076640 AU - Elbers AR AU - van Rossem H AU - Schukken YH AU - Martin SW AU - van Exsel AC AU - Friendship RM AU - Tielen MJ TI - Return to oestrus after first insemination in sow herds (incidence, seasonality, and association with reproductivity and some blood parameters). LA - Eng MH - Animal MH - Estrus/*physiology MH - Female MH - *Insemination MH - Prospective Studies MH - Reproduction/physiology MH - Retrospective Studies MH - Seasons MH - Swine/blood/*physiology PT - JOURNAL ARTICLE DA - 950105 DP - 1994 Jul IS - 0165-2176 TA - Vet Q PG - 100-9 SB - M CY - NETHERLANDS IP - 2 VI - 16 JC - XBT AA - Author EM - 9503 AB - As no systematic study has been done to get an accurate estimate of the incidence of return to oestrus after first insemination in sows in the Netherlands, the objectives of this investigation were: 1) to obtain an estimate of the incidence of return to oestrus after insemination at the herd level; 2) to investigate the association between incidence of return to oestrus after first insemination and reproduction characteristics in order to get an impression of the economic importance of reproductive failure. These objectives were investigated by using the reproduction results of 240 swine breeding herds in the Southern Netherlands in 1987. This information was obtained from CBK plus computerized herd management records. The average incidence rate of return to oestrus after first insemination at a herd level was 16.9 per 100 first inseminations. The occurrence of return to oestrus after first insemination was distinctly higher in the insemination months July and August compared to the rest of the year. An increased incidence, with 10 returns per 100 first inseminations corrected for confounders in a multiple linear regression model, was associated with a decrease of approximately 0.3 live born piglets/sow/year. A prospective longitudinal study was started in 1988 and 1989 in 37 sow herds. Individual sows were monitored from weaning to first insemination, to the occurrence of return to oestrus, or not, after first insemination, and to farrowing. The investigation focused in particular on the relationship between return to oestrus after first insemination and seroconversion against porcine parvovirus (PPV) and Leptospira interrogans serovar bratislava (L. bratislava).(ABSTRACT TRUNCATED AT 250 WORDS) AD - Animal Health Service in the Southern Netherlands, Boxtel. PMID- 7985351 SO - Vet Q 1994 Jul;16(2):100-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 95035606 AU - van Crevel R AU - Speelman P AU - Gravekamp C AU - Terpstra WJ TI - Leptospirosis in travelers. LA - Eng MH - Asia, Southeastern MH - Community-Acquired Infections/etiology MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*etiology/pathology MH - Serotyping MH - Thailand MH - *Travel MH - Water Microbiology PT - JOURNAL ARTICLE DA - 941212 DP - 1994 Jul IS - 1058-4838 TA - Clin Infect Dis PG - 132-4 SB - M CY - UNITED STATES IP - 1 VI - 19 JC - A4J AA - Author EM - 9502 AB - Between 1987 and 1991 leptospirosis in 32 Dutch travelers was diagnosed. Infections were acquired predominantly in Thailand and other Southeast Asian countries. Contact with surface waters could be confirmed in all but one case. Fever, headache, and myalgia were the most common complaints. Signs included conjunctival injection and lymphadenopathy in 11 patients each, jaundice in 8, and nuchal rigidity in 3; renal function was impaired in 8. Leptospires were isolated from the blood or urine of nine patients. Thirty-one patients developed an antibody response. Classification of strains identified a variety of serogroups. Although only 14 patients received adequate treatment, all patients recovered completely. Since the number of patients with imported leptospirosis is increasing and the signs and symptoms of the disease are not specific, leptospirosis should be included in the differential diagnosis when a traveler returns from the Tropics with fever. AD - Department of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands. PMID- 7948513 SO - Clin Infect Dis 1994 Jul;19(1):132-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 95031806 AU - Ellis GR AU - Partington DL AU - Hindmarsh M AU - Barton MD TI - Seroprevalence to Leptospira interrogans serovar hardjo in merino stud rams in South Australia. LA - Eng MH - Agglutination Tests/veterinary MH - Analysis of Variance MH - Animal MH - Antibodies, Bacterial/*blood MH - Breeding MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - IgG/blood MH - IgM/blood MH - Leptospira interrogans/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Prevalence MH - Rain MH - Regression Analysis MH - Seasons MH - Seroepidemiologic Methods MH - Sheep MH - Sheep Diseases/*epidemiology MH - South Australia/epidemiology MH - Support, Non-U.S. Gov't MH - Water Supply RN - 0 (Antibodies, Bacterial) RN - 0 (IgG) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 941118 DP - 1994 Jul IS - 0005-0423 TA - Aust Vet J PG - 203-6 SB - M CY - AUSTRALIA IP - 7 VI - 71 JC - 9IE AA - Author EM - 9501 AB - A serological survey of 2160 Merino stud rams on 36 farms detected positive reactions greater than or equal to 1/100 in 42% of animals using the microscopic agglutination test (MAT) to Leptospira interrogans serovar hardjo. Twenty flocks had seroprevalence values greater than 30% with 15 flocks having values > or = 60%. The enzyme- linked immunosorbent assays showed that 47% and 3% of rams on the 36 farms were positive for IgG and IgM antibodies, respectively. Forty- five percent of hardjo reactions were in rams that had not been exposed to cattle. Significant correlations were found between IgM reactors and creek/dam water pumped into troughs, and between MAT/IgG reactors and total flock size. No statistical relationships were detected between positive reactors and two different annual average rainfall gradients, the time of the year in which samples were obtained, or agricultural regions of South Australia. Infections with an organism of the Sejroe serogroup is widespread in Merino stud rams. AD - Central Veterinary Laboratories, South Australian Department of Primary Industries, Adelaide. PMID- 7945098 SO - Aust Vet J 1994 Jul;71(7):203-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [15 medline neighbors] UI - 95018867 AU - Howerth EW AU - Reeves AJ AU - McElveen MR AU - Austin FW TI - Survey for selected diseases in nutria (Myocastor coypus) from Louisiana. LA - Eng MH - Animal MH - Antibodies/blood MH - Chlamydia psittaci/immunology MH - Communicable Diseases/epidemiology/*veterinary MH - Encephalomyocarditis Virus/immunology MH - Feces/microbiology/parasitology MH - Female MH - Francisella tularensis/immunology MH - Giardia/isolation & purification MH - Leptospira/immunology MH - Louisiana/epidemiology MH - Male MH - Pregnancy MH - Pregnancy Complications, Infectious/epidemiology/veterinary MH - Pregnancy Complications, Parasitic/epidemiology/veterinary MH - Prevalence MH - Rodent Diseases/*epidemiology MH - Rodentia MH - Salmonella/isolation & purification MH - Seroepidemiologic Methods MH - Toxoplasma/immunology RN - 0 (Antibodies) PT - JOURNAL ARTICLE DA - 941121 DP - 1994 Jul IS - 0090-3558 TA - J Wildl Dis PG - 450-3 SB - M CY - UNITED STATES IP - 3 VI - 30 JC - KEM AA - Author EM - 9501 AB - Thirty-two trapper-caught nutria (Myocastor coypus) from East Baton Rouge, Iberville, Tangipahoa, and St. Helena Parishes in Louisiana (USA) were sampled for several disease agents. Antibodies against Toxoplasma gondii, Chlamydia psittaci, Francisella tularensis, Leptospira spp., and encephalomyocarditis virus were detected in 7%, 14%, 0%, 7%, and 0% of nutria, respectively. Both animals seropositive for leptospirae were positive for L. interrogans serovar canicola. No Salmonella spp. were isolated from feces, and no Giardia spp. were seen in trichrome-stained fecal preparations. AD - Louisiana Veterinary Medical Diagnostic Laboratory, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803. PMID- 7933295 SO - J Wildl Dis 1994 Jul;30(3):450-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 95018864 AU - Isogai E AU - Isogai H AU - Kawabata H AU - Masuzawa T AU - Yanagihara Y AU - Kimura K AU - Sakai T AU - Azuma Y AU - Fujii N AU - Ohno S TI - Lyme disease spirochetes in a wild fox (Vulpes vulpes schrencki) and in ticks. LA - Eng MH - Animal MH - Animals, Wild MH - Antibodies, Bacterial/blood MH - Arachnid Vectors/*microbiology MH - Borrelia/genetics/immunology/*isolation & purification MH - Disease Reservoirs MH - DNA, Bacterial/analysis MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Female MH - Foxes/*microbiology/parasitology MH - Lyme Disease/microbiology/pathology/transmission/*veterinary MH - Male MH - Skin/microbiology/pathology MH - Tick Infestations/pathology/parasitology/*veterinary MH - Ticks/*microbiology RN - 0 (Antibodies, Bacterial) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 941121 DP - 1994 Jul IS - 0090-3558 TA - J Wildl Dis PG - 439-44 SB - M CY - UNITED STATES IP - 3 VI - 30 JC - KEM AA - Author EM - 9501 AB - Lyme disease spirochetes were demonstrated in a wild female fox (Vulpes vulpes schrencki) and in Ixodes persulcatus ticks collected from the fox on Sapporo, Hokkaido, Japan. Spirochetes were detected in I. persulcatus, as well as skin lesions, brain, heart, kidney, and liver of the fox. Five of seven isolates reacted with a monoclonal antibody against Borrelia afzelii specific Osp B. Deoxyribonucleic acid (DNA) relatedness of a brain isolate was 89% to B. afzelii, and ranged from 50 to 67% to three other species. Immunoglobulin G antibodies to B. afzelii, B. garinii and B. burgdorferi sensulato, when tested in an enzyme-linked immunosorbent assay (ELISA), were negative in the fox. There were no antibodies against seven serovars of Leptospira interrogans. AD - Department of Preventive Dentistry, Higashi Nippon Gakuen University, Hokkaido, Japan. PMID- 7933292 SO - J Wildl Dis 1994 Jul;30(3):439-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 94347618 AU - Feresu SB AU - Bolin CA AU - Korver H AU - Terpstra WJ TI - Classification of leptospires of the pyrogenes serogroup isolated from cattle in Zimbabwe by cross-agglutinin absorption and restriction fragment length polymorphism analysis. LA - Eng MH - Agglutinins MH - Animal MH - Antigens, Bacterial MH - Cattle/*microbiology MH - Immunosorbent Techniques MH - Leptospira/*classification/genetics/immunology MH - Polymorphism, Restriction Fragment Length MH - Serotyping MH - Species Specificity MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Zimbabwe RN - 0 (Agglutinins) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE ID - IF 05 TW 4154-01/TW/FIC DA - 940929 DP - 1994 Jul IS - 0020-7713 TA - Int J Syst Bacteriol PG - 541-6 SB - M CY - UNITED STATES IP - 3 VI - 44 JC - AWO AA - Author EM - 9412 AB - Five strains of the genus Leptospira belonging to serogroup Pyrogenes were isolated from cattle slaughtered in Zimbabwe and subjected to cross-agglutinin absorption and restriction fragment length polymorphism analysis. One strain, SBF 2, represents a new genetic strain of serovar kwale, while another strain, SBF 49, is a new genetic strain closely related to serovar nigeria. Three strains belong to a new serovar for which the name mombe with reference strain SBF 20 is proposed. Restriction fragment length polymorphism analysis indicated that each of these three strains represents a different restriction polymorphism pattern group. AD - Department of Biological Sciences, University of Zimbabwe, Mount Pleasant, Harare. PMID- 7915129 CU - 94 SO - Int J Syst Bacteriol 1994 Jul;44(3):541-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 95099761 AU - Yukawa M AU - Mochizuki K AU - Kosaka T AU - Kamata H AU - Awaya A AU - Kobayashi H AU - Onodera T TI - Protective effects of serum thymic factor to Leptospira interrogans serovar Copenhageni infection in Mongolian gerbils. LA - Eng MH - Animal MH - Disease Models, Animal MH - Gerbillinae MH - Killer Cells, Natural/immunology MH - Leptospira interrogans/classification/*immunology MH - Macrophages/immunology MH - Male MH - Serotyping MH - Thymic Factor, Circulating/administration & dosage/*pharmacology MH - Weil's Disease/immunology/pathology/*prevention & control RN - 78922-62-0 (Thymic Factor, Circulating) PT - JOURNAL ARTICLE DA - 950120 DP - 1994 Jul IS - 0378-1135 TA - Vet Microbiol PG - 99-106 SB - M CY - NETHERLANDS IP - 1-2 VI - 41 JC - XBW AA - Author EM - 9503 AB - The susceptibility to Leptospira interrogans serovar copenhageni in Mongolian gerbils treated with 10 micrograms of serum thymic factor (FTS) 1 day before infection was examined. Susceptibility of gerbils treated 5 times with 10 micrograms of FTS was also investigated. Mortality of FTS-treated gerbils was significantly lower than that of controls when small challenge doses were used. To analyse the FTS- induced resistance to leptospiral infection, natural killer (NK) cell activity and macrophage activity were studied. Macrophage activity was unaltered but NK cell activity was enhanced in FTS-treated gerbils, with or without leptospiral infection. Since no side-effects of FTS were observed, this compound should be considered for the treatment of leptospirosis. AD - Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Nihon University, Kanagawa, Japan. PMID- 7801529 SO - Vet Microbiol 1994 Jul;41(1-2):99-106 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 95099760 AU - Gitton X AU - Daubie MB AU - Andre F AU - Ganiere JP AU - Andre-Fontaine G TI - Recognition of Leptospira interrogans antigens by vaccinated or infected dogs. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Antibody Specificity MH - *Antigens, Bacterial/chemistry/isolation & purification MH - Bacterial Vaccines/*pharmacology MH - Blotting, Western MH - Comparative Study MH - Dogs MH - Hemagglutination Tests MH - Leptospira interrogans/classification/*immunology/pathogenicity MH - Lipopolysaccharides/chemistry/immunology/isolation & purification MH - Molecular Weight MH - Serotyping MH - Support, Non-U.S. Gov't MH - Vaccination MH - Virulence/immunology MH - Weil's Disease/*immunology/prevention & control RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 950120 DP - 1994 Jul IS - 0378-1135 TA - Vet Microbiol PG - 87-97 SB - M CY - NETHERLANDS IP - 1-2 VI - 41 JC - XBW AA - Author EM - 9503 AB - Antigenic recognition of leptospiral antigens by vaccinated or infected dogs was studied by microagglutination test (MAT) and by western blots. In western blots, serovar specific antigens detected by MAT migrated in the 18-31 kDa zone. The 25-31 zone seemed to be linked to antigens indicating virulence of the strain. These antigens are LPS. The first antibodies made after infection are produced against LPS migrating in the 14 kDa zone. Many protein antigens are common in leptospires belonging to different serogroups. Virulent strains exhibited specific antigens in the 45 and 32-34 kDa zones. AD - Ecole Nationale Veterinaire de Nantes, France. PMID- 7801528 SO - Vet Microbiol 1994 Jul;41(1-2):87-97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 95307597 AU - dos Santos VM TI - [Leptospirosis and pulmonary hantavirus syndrome (letter)] LA - Por MH - Diagnosis, Differential MH - Hantavirus Infections/*diagnosis MH - Human MH - Leptospirosis/*diagnosis MH - Lung Diseases/*diagnosis/VI PT - LETTER DA - 950727 DP - 1994 Jul-Sep IS - 0104-4230 TA - Rev Assoc Med Bras PG - 225 CY - BRAZIL IP - 3 VI - 40 JC - BR5 EM - 9509 PMID- 7787876 CU - 96 TT - Leptospirose e sindrome pulmonar por hantavirus. SO - Rev Assoc Med Bras 1994 Jul-Sep;40(3):225 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 96001434 AU - Fuentes AM AU - Gonzalez AO AU - Serrano JL TI - ELISA for the detection of human leptospirosis. LA - Eng MH - Antibodies, Bacterial/blood MH - Blood Donors MH - Cuba MH - *Enzyme-Linked Immunosorbent Assay MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis MH - Sensitivity and Specificity RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 951212 DP - 1994 Jul-Sep IS - 0074-0276 TA - Mem Inst Oswaldo Cruz PG - 365 SB - M CY - BRAZIL IP - 3 VI - 89 JC - MRY EM - 9602 AD - Instituto de Medicina Tropical Pedro Kouri, Laboratorio Nacional de Referencia de Leptospira, Ciudad de la Habana, Cuba. PMID- 7476217 SO - Mem Inst Oswaldo Cruz 1994 Jul-Sep;89(3):365 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 94338935 TI - Veterinary public health. Leptospirosis in 1993. LA - Eng LA - Fre MH - Animal MH - Cross-Sectional Studies MH - Female MH - France/epidemiology MH - Human MH - Incidence MH - Leptospirosis/epidemiology/*transmission MH - Male MH - *Zoonoses PT - JOURNAL ARTICLE DA - 940920 DP - 1994 Jun 17 IS - 0049-8114 TA - Wkly Epidemiol Rec PG - 182-3 CY - SWITZERLAND IP - 24 VI - 69 JC - AVX EM - 9411 PMID- 8060835 NI - A SO - Wkly Epidemiol Rec 1994 Jun 17;69(24):182-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 94368926 AU - Emmanouilides CE AU - Kohn OF AU - Garibaldi R TI - Leptospirosis complicated by a Jarisch-Herxheimer reaction and adult respiratory distress syndrome: case report [see comments] LA - Eng MH - Case Report MH - Drug Eruptions/*etiology MH - Human MH - *Leptospira interrogans MH - Leptospirosis/*complications/drug therapy MH - Male MH - Middle Age MH - Penicillins/adverse effects/therapeutic use MH - Respiratory Distress Syndrome, Adult/*etiology RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 941018 DP - 1994 Jun IS - 1058-4838 TA - Clin Infect Dis PG - 1004-6 SB - M CY - UNITED STATES IP - 6 VI - 18 JC - A4J AA - Author EM - 9412 AB - Leptospirosis, severe infection due to Leptospira interrogans, is a potentially lethal disease that causes multiple organ failure. In addition to hepatic, renal, and CNS involvement, which are classic complications of leptospirosis, the disease may also be complicated by adult respiratory distress syndrome. Treatment with penicillin may precipitate a severe Jarisch-Herxheimer reaction. The mechanisms of Leptospira-induced toxicity remain obscure. We report a near-fatal case of leptospirosis in a patient who developed a JHR and respiratory failure immediately after initiation of therapy. AD - Department of Medicine, University of Connecticut School of Medicine, Farmington. CM - Comment in: Clin Infect Dis 1995 May;20(5):1437-8 RO - M:LC2 PMID- 8086528 LR - 951016 SO - Clin Infect Dis 1994 Jun;18(6):1004-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 94273792 AU - Morshed MG AU - Konishi H AU - Terada Y AU - Arimitsu Y AU - Nakazawa T TI - Seroprevalence of leptospirosis in a rural flood prone district of Bangladesh. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*blood MH - Bangladesh/epidemiology MH - Female MH - Human MH - Leptospira/*classification/*immunology/isolation & purification MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Natural Disasters MH - Prevalence MH - Risk Factors MH - *Rural Health MH - Seroepidemiologic Methods RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940721 DP - 1994 Jun IS - 0950-2688 TA - Epidemiol Infect PG - 527-31 SB - M CY - ENGLAND IP - 3 VI - 112 JC - EPI AA - Author EM - 9409 AB - Leptospirosis is a worldwide zoonotic disease. In the present investigation, a total of 89 human sera from a flood prone district of Bangladesh was screened by a one-point microscapsule agglutination test (MCAT). MCAT-positive and -doubtful sera were further tested by microscopic agglutination test (MAT) against 16 reference serovars of Leptospira interrogans, and the antibody titres determined. In MCAT, 34 sera were positive and 22 were doubtful. Among those positive and doubtful sera, 33 and 20, respectively were tested by MAT. Thirty-four out of 53 MCAT-screened samples were MAT-positive. The titres ranged from 20 to 1600 with antibodies to serovars copenhageni, australis, cynopteri and icterohaemorrhagiae being the most prevalent. Eleven MCAT- positive samples failed to react with any strains used by MAT, suggesting the presence of new or untested serovars. Among the MAT- positive samples, the presence of antibody against two or more serovars was more common than that of a single serovar. The present study suggests that rural people in Bangladesh are at high risk to leptospiral infection. AD - Department of Microbiology, Yamaguchi University School of Medicine, Japan. PMID- 8005218 SO - Epidemiol Infect 1994 Jun;112(3):527-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 95045612 AU - Torre D AU - Giola M AU - Martegani R AU - Zeroli C AU - Fiori GP AU - Ferrario G AU - Bonetta G TI - Aseptic meningitis caused by Leptospira australis. LA - Eng MH - Adult MH - Agglutination Tests MH - Antibodies, Bacterial/blood MH - Case Report MH - Ceftriaxone/therapeutic use MH - Diagnosis, Differential MH - Human MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/drug therapy/*microbiology MH - Male MH - Meningitis, Aseptic/diagnosis/drug therapy/*microbiology RN - 0 (Antibodies, Bacterial) RN - 73384-59-5 (Ceftriaxone) PT - JOURNAL ARTICLE DA - 941208 DP - 1994 Jun IS - 0934-9723 TA - Eur J Clin Microbiol Infect Dis PG - 496-7 SB - M CY - GERMANY IP - 6 VI - 13 JC - EM5 AA - Author EM - 9502 AB - Meningeal involvement in leptospiral infection is quite common, usually mild and often overlooked. In contrast, cases of isolated involvement of the central nervous system, including aseptic meningitis, have been reported only rarely. A case of a patient with acute aseptic meningitis caused by Leptospira australis serovar bratislava is reported. This is believed to be the first report of aseptic meningitis due to Leptospira australis. This case indicates the need to consider human leptospirosis in the differential diagnosis of aseptic meningitis. AD - Division of Infectious Diseases, Regional Hospital, Varese, Italy. PMID- 7957270 SO - Eur J Clin Microbiol Infect Dis 1994 Jun;13(6):496-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 95027818 AU - Liutov VV AU - Alekseev VG AU - Kozlovskii IA AU - Liutov VV AU - Cherniak NM TI - [Leptospirosis: its diagnostic and treatment characteristics] LA - Rus MH - Acute Disease MH - Combined Modality Therapy MH - Diagnosis, Differential MH - Human MH - Leptospirosis/complications/*diagnosis/therapy MH - *Military Personnel MH - Russia MH - Time Factors PT - JOURNAL ARTICLE DA - 941123 DP - 1994 Jun IS - 0026-9050 TA - Voen Med Zh PG - 41-3 CY - RUSSIA IP - 6 JC - XGS EM - 9501 PMID- 7941453 TT - Leptospiroz: osobennosti diagnostiki i lecheniia. SO - Voen Med Zh 1994 Jun;(6):41-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 95027650 AU - Woodward MJ AU - Redstone JS TI - Deoxynucleotide sequence conservation of the endoflagellin subunit protein gene, flaB, within the genus Leptospira. LA - Eng MH - Amino Acid Sequence MH - Base Sequence MH - Conserved Sequence/*genetics MH - Flagellin/*genetics MH - Genes, Bacterial/*genetics MH - Leptospira/*chemistry MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - Restriction Mapping MH - Sequence Analysis, DNA MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 12777-81-0 (Flagellin) PT - JOURNAL ARTICLE DA - 941108 DP - 1994 Jun IS - 0378-1135 TA - Vet Microbiol PG - 239-51 SB - M CY - NETHERLANDS IP - 3-4 VI - 40 JC - XBW AA - Author EM - 9501 AB - A Polymerase chain reaction was developed to amplify the entire open reading frame of flaB, the gene encoding the endoflagellin subunit protein. The 852 bp amplified products from 23 serovars of the genus Leptospira were subjected to restriction endonuclease analysis and the profiles correlated well with phylogenetic relationships between these serovars. The flaB deoxynucleotide sequences of L. hardjo-bovis, L. hardjo-prajitno and L. grippotyphosa were determined. The deduced primary amino acid sequences of each were highly conserved with only three amino acid residue differences observed. The deoxynucleotide sequences showed genetic drift with alternative bases in the third position of codons. The PCR product derived by amplification of flaB from L. grippotyphosa was cloned into the expression vector pGEX-2T and a recombinant FlaB fusion protein made. As predicted from the deduced amino acid sequences, the recombinant FlaB cross-reacted with heterologous antiserum derived from a rabbit infected with L. hardjo- bovis. AD - Molecular Genetics Unit, Bacteriology R&D Discipline, Central Veterinary Laboratory, New Haw, Surrey, UK. PMID- 7941289 GS - flaB SO - Vet Microbiol 1994 Jun;40(3-4):239-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [210 medline neighbors] UI - 95104814 AU - Wu W AU - Dai B TI - [16S rRNA reverse transcription-polymerase chain reaction of leptospires] LA - Chi MH - Base Sequence MH - Comparative Study MH - DNA Primers MH - DNA, Bacterial/genetics MH - English Abstract MH - Leptospira/genetics MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - Polymerase Chain Reaction/methods MH - RNA-Directed DNA Polymerase MH - RNA, Ribosomal, 16S/*genetics MH - Support, Non-U.S. Gov't RN - EC 2.7.7.49 (RNA-Directed DNA Polymerase) RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 950131 DP - 1994 Jun IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 166-9 CY - CHINA IP - 2 VI - 25 JC - GEB AA - Author EM - 9504 AB - We amplified the leptospiral RNAs of Leptospira interrogans serovar lai strain Lai and L. biflexa serovar patoc strain Patoc I, extracted by the method of SiO2-high concentration salt solution (8 mol/L GuHCl) absorption, with the 16S rRNA gene primers of Leptospira interrogans by reverse transcription-polymerase chain reaction (RT-PCR). It demonstrated that the detecting sensitivity by naked eye after electrophoresis could be 100 times higher when we amplified DNA and RNA of leptospires at the same time by RT-PCR. PMID- 7528714 CU - 95 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1994 Jun;25(2):166-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 95023704 AU - Gouello JP AU - Deslandes V AU - Chennebault JM AU - Bouachour G AU - Perroux D AU - Alquier P TI - [Isolated meningoencephalitis revealing leptospirosis (letter)] LA - Fre MH - Adult MH - Case Report MH - Epilepsy/etiology MH - Fatal Outcome MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/complications/diagnosis/*microbiology MH - Meningitis, Bacterial/complications/*microbiology PT - LETTER DA - 941103 DP - 1994 May 28 IS - 0755-4982 TA - Presse Med PG - 952 SB - M SB - X CY - FRANCE IP - 20 VI - 23 JC - PMT EM - 9501 PMID- 7937636 TT - Meningo-encephalite isolee revelant une leptospirose. SO - Presse Med 1994 May 28;23(20):952 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 96134082 AU - Carter SD AU - May C AU - Barnes A AU - Bennett D TI - Borrelia burgdorferi infection in UK horses [see comments] LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis/*blood/immunology MH - Blotting, Western MH - Borrelia burgdorferi/*immunology MH - Cross Reactions MH - Dogs MH - Enzyme-Linked Immunosorbent Assay MH - Great Britain/epidemiology MH - Horse Diseases/diagnosis/*epidemiology/microbiology MH - Horses MH - Human MH - IgG/analysis/blood/immunology MH - IgM/analysis/blood/immunology MH - Incidence MH - Leptospira/immunology MH - Lyme Disease/diagnosis/epidemiology/*veterinary MH - Seroepidemiologic Methods MH - Species Specificity MH - Support, Non-U.S. Gov't MH - Synovial Fluid/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (IgG) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 960214 DP - 1994 May IS - 0425-1644 TA - Equine Vet J PG - 187-90 SB - M CY - ENGLAND IP - 3 VI - 26 JC - EJ9 AA - Author EM - 9604 AB - Antibody levels (IgG and IgM) to Borrelia burgdorferi were measured in the sera and synovial fluids of UK horses. Western blotting against B. burgdorferi was also used on samples from seropositive horses. A low incidence of seropositivity was shown in horses from most parts of the UK. This increased in areas that have a high incidence of human and canine borreliosis (Norfolk and south coast). Leptospira infections of horses did not cause cross reactions in the B. burgdorferi ELISA. Most horses did not display clinical signs of Lyme disease. As with dogs and man, it is apparent that B. burgdorferi infection occurs in horses in the UK but clinical Lyme disease is uncommon. AD - Department of Veterinary Pathology, Animal Husbandry University of Liverpool, UK. CM - Comment in: Equine Vet J 1994 May;26(3):175-7 PMID- 8542836 SO - Equine Vet J 1994 May;26(3):187-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 94327782 AU - de Caballero OL AU - Dias Neto E AU - Koury MC AU - Romanha AJ AU - Simpson AJ TI - Low-stringency PCR with diagnostically useful primers for identification of Leptospira serovars. LA - Eng MH - Bacteriological Techniques/statistics & numerical data/standards MH - Base Sequence MH - DNA Primers/*genetics MH - DNA, Bacterial/genetics MH - Evaluation Studies MH - Human MH - Leptospira/classification/*genetics/*isolation & purification MH - Leptospirosis/diagnosis MH - Molecular Sequence Data MH - Polymerase Chain Reaction/*methods/statistics & numerical data/standards MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940902 DP - 1994 May IS - 0095-1137 TA - J Clin Microbiol PG - 1369-72 SB - M CY - UNITED STATES IP - 5 VI - 32 JC - HSH AA - Author EM - 9411 AB - Primers proposed for the diagnosis of the pathogenic spirochete Leptospira spp. (C. Gravekamp, H. V. D. Kemp, M. Franzen, D. Carrington, G.J. Schoone, G.J.J.M. Van Eys, C. O. R. Everard, R.A. Hartskeel, and W.J. Terpstra, J. Gen. Microbiol. 139:1691-1700, 1993) have been found to produce complex serovar-specific patterns under low- stringency PCR conditions. Such patterns obtained by low-stringency PCR, which maintain the specific band as an internal control, offer, an approach to the standardized identification of Leptospira serovars in clinical laboratories. AD - Centro de Pesquisas Rene Rachou, FIOCRUZ, Minas Gerais, Brazil. PMID- 8051272 SO - J Clin Microbiol 1994 May;32(5):1369-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 94301615 AU - Payling K TI - Leptospirosis: identification and management. LA - Eng MH - Human MH - Leptospirosis/*diagnosis/prevention & control/therapy MH - Occupational Diseases/*diagnosis/prevention & control/therapy PT - JOURNAL ARTICLE DA - 940811 DP - 1994 May IS - 0029-7917 TA - Occup Health (Lond) PG - 164-5 SB - N CY - ENGLAND IP - 5 VI - 46 JC - ODB EM - 9410 PMID- 8028849 LI - N SO - Occup Health (Lond) 1994 May;46(5):164-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 94290862 AU - Prokopcakova H AU - Peterkova J AU - Pet'ko B AU - Stanko M AU - Cislakova L AU - Palinsky M TI - [Occurrence of Leptospira serovars in old foci of leptospirosis] LA - Slo MH - Animal MH - Disease Reservoirs MH - *Disease Vectors MH - English Abstract MH - Female MH - Human MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/*epidemiology/microbiology MH - Male MH - Mammals/microbiology MH - Slovakia/epidemiology PT - JOURNAL ARTICLE DA - 940804 DP - 1994 May IS - 0009-5222 TA - Epidemiol Mikrobiol Imunol PG - 87-9 CY - CZECH REPUBLIC IP - 2 VI - 43 JC - B10 AA - Author EM - 9410 AB - In two old natural foci of leptospiroses in an Eastern Slovakian area an epidemiological investigation was made to detect persisting carriership in basis reservoirs-small mammals and the contact with leptospirae in population groups with an occupational risk. Using the microagglutination reaction (MAR), the authors examined 1,106 small mammals and detected in 50 cases, i.e. 4.5%, the presence of specific antibodies against leptospirae, most frequently in species Apodemus agrarius and Ap. flavicollis. Only in one instance a positive reaction was found in the main reservoir--Microtus arvalis. As to serovars, Leptospira grippotyphosa and the group L. sejroe dominated. Of 1,740 examined human sera (832 men, 908 women) 56 samples (3.2%) reacted in MAR (4.1% men, 2.4% women). The spectrum of serovars in positive subjects was the same as in the above mentioned reservoirs with a predominance of L. grippotyphosa and group L. sejroe. As compared with previous examinations made 18 years ago in small mammals, a decline of positivity to almost half was recorded (from 7.8% to 4.5%), a reduction of the number of serovars from 7 to 4 was observed, however, the positivity of dominating serovars did not decline. In humans a higher percentage of positivity to specific antibodies was found, as compared with the past, i.e. 3.0% as compared with 2.0%. The authors found differences in the frequency of different serovars. In the past serovar L. bratislava dominated in the above area, followed by L. grippotyphosa. At present the first place was held by L. grippotyphosa and the group of L. sejroe.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Ustav hygieny a epidemiologie, Lekarska fakulta UPJS, Kosice. PMID- 8019818 TT - Sucasny stav vyskytu leptospirovych serovarov v starych ohniskach leptospiroz. EA - A SO - Epidemiol Mikrobiol Imunol 1994 May;43(2):87-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 95133303 AU - Mel'nitskaia EV TI - [The prospects for using an indirect immunoenzyme method for the diagnosis of leptospirosis] LA - Rus MH - Antibodies, Bacterial/blood MH - Antibody Specificity MH - Comparative Study MH - English Abstract MH - Evaluation Studies MH - Human MH - Immunoenzyme Techniques MH - Leptospira/classification/immunology MH - Leptospirosis/*diagnosis MH - Sensitivity and Specificity MH - Serotyping MH - Time Factors RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950223 DP - 1994 May-Jun IS - 1019-5297 TA - Lik Sprava PG - 64-6 CY - UKRAINE IP - 5-6 JC - CIU AA - Author EM - 9504 AB - An evaluation was carried out of sensitivity and specificity of indirect enzyme immunoassay to be used for the identification of antileptospiral antibodies in the patients' sera. Ultrasonic antigenic preparations were used as an antigen. The test permits determining genus-specific antibodies as well as those of more restricted specificity including serogroup-specific ones. Time course of changes is presented of antibodies in different phases of the disease. In leptospiral patients the spectrum of the antibodies identified broadens with the use of polyvalent antigenic preparations. PMID- 7831914 CU - 96 TT - Perspektivy primeneniia nepriamogo immunofermentnogo metoda dlia diagnostiki leptospiroza. EA - A SO - Lik Sprava 1994 May-Jun;(5-6):64-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 95099955 AU - Sting R AU - Dura U TI - Isolation of serovar-specific leptospiral antigens for use in an enzyme- linked immunosorbent assay (ELISA) compared with the microscopic agglutination test and immunofluorescence. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/blood MH - Antigens, Bacterial/diagnostic use/*isolation & purification MH - Cattle MH - Comparative Study MH - Dogs MH - Enzyme-Linked Immunosorbent Assay/*veterinary MH - Fluorescent Antibody Technique/veterinary MH - Horses MH - Leptospira/*immunology MH - Rabbits MH - Support, Non-U.S. Gov't MH - Swine RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 950124 DP - 1994 May IS - 0931-1793 TA - Zentralbl Veterinarmed [B] PG - 166-75 CY - GERMANY IP - 3 VI - 41 JC - Y72 AA - Author EM - 9503 AB - A total of 10 different detergents were used with the intention of extracting serovar-specific antigens from eight leptospiral serovars for use in an ELISA. Extractions with 2% sodium taurocholate at 50 degrees C proved to be best suited for this purpose. Taurocholate extracted antigens could be separated in SDS-PAGE and antigenic activities demonstrated in immunoblotting. In comparative studies on sera taken from cattle, pigs, horses and dogs, the self-made ELISA proved to be more sensitive than the microscopic agglutination test (MAT) and the immunofluorescence test (IFT). The IFT gave different results from those obtained using MAT or ELISA. AD - Staatliches Tierarztliches Untersuchungsamt Stuttgart, Germany. PMID- 7801719 SO - Zentralbl Veterinarmed [B] 1994 May;41(3):166-75 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [126 medline neighbors] UI - 94259269 AU - Hookey JV AU - Barrett SP AU - Reed CS AU - Barber P TI - Phylogeny of human intestinal spirochaetes inferred from 16S rDNA sequence comparisons. LA - Eng MH - Comparative Study MH - DNA, Ribosomal/*chemistry MH - Human MH - Intestines/*microbiology MH - Phylogeny MH - RNA, Ribosomal, 16S/*genetics MH - Spirochaetales/*genetics RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 940705 DP - 1994 Apr 15 IS - 0378-1097 TA - FEMS Microbiol Lett PG - 345-9 SB - M CY - NETHERLANDS IP - 3 VI - 117 JC - FML AA - Author EM - 9409 AB - The sequence of 1383 nucleotides of the DNA encoding 16S rDNA was determined for strains of human intestinal spirochaetes, comprising an unnamed isolate and "Brachyspira aalborgi" NCTC 11492. A phylogenetic tree was inferred from aligned sequence comparisons between the intestinal spirochaetes, representatives of the Spirochaetales and Escherichia coli. The type strain of Brachyspira aalborgi, though related to the Serpulina spp. at approx. 96.5% sequence similarity was distinct and separated from the unnamed human intestinal isolate, HIS Oman, N26. The latter formed a separated and novel lineage that bisected the Spirochaetales. AD - Leptospira Reference Laboratory, FAO/WHO Collaborating Centre, County Hospital, Hereford, UK. PMID- 8200510 SO - FEMS Microbiol Lett 1994 Apr 15;117(3):345-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [18 medline neighbors] UI - 94246326 AU - Thomas DR AU - Salmon RL AU - Kench SM AU - Meadows D AU - Coleman TJ AU - Morgan-Capner P AU - Morgan KL TI - Zoonotic illness--determining risks and measuring effects: association between current animal exposure and a history of illness in a well characterised rural population in the UK. LA - Eng MH - Adult MH - Agricultural Workers' Diseases/*etiology MH - Animal MH - England MH - Female MH - Human MH - Infectious Mononucleosis/prevention & control MH - Leptospirosis/etiology MH - Longitudinal Studies MH - Male MH - Middle Age MH - *Occupational Exposure MH - Pneumonia/etiology MH - Random Allocation MH - Rheumatic Fever/prevention & control MH - Risk Factors MH - *Rural Health MH - Scarlet Fever/prevention & control MH - Support, Non-U.S. Gov't MH - Zoonoses/*etiology PT - JOURNAL ARTICLE DA - 940621 DP - 1994 Apr IS - 0143-005X TA - J Epidemiol Community Health PG - 151-5 SB - M CY - ENGLAND IP - 2 VI - 48 JC - I1P AA - Author EM - 9408 AB - STUDY OBJECTIVES--To recruit a representative sample of farmworkers, accurately quantify the range and extent of their animal exposures, and measure the associated risks of illness. DESIGN--Inception cohort. SETTING--The study was undertaken among farmworkers living in five local authority areas in the catchment of Hereford and Preston Public Health Laboratories, England. PARTICIPANTS--A quota sample of 404 people on 255 agricultural holdings took part. The holdings were selected at random from the Ministry of Agriculture, Fisheries and Food register. Altogether 58% of eligible subjects approached agreed to participate. MEASUREMENTS AND MAIN RESULTS--The sample had the same sex distribution as the 1991 census for those giving their occupation as agriculture. The mean age was significantly (p < 0.01) higher (44.6 years v 42.2 years) than that of those giving their occupation as agriculture, forestry or fishing in the census, although the modal range (45-59 years) was the same. At enrollment interviews, subjects individually reported contact with up to nine animal species (mode 4) out of 26 reported in all. Based on the numbers contacted and the frequency and intimacy of contact, scores on a ranked ordinal scale from 0-5 were constructed for each species and frequencies for each score were plotted. Subjects also reported past operations and serious illness. A history of pneumonia was significantly (p < 0.05) associated with a pigeon loft on the farm (relative risk (RR) 7.3) and attending farrowing pigs (RR 6.6), and one of leptospirosis with a rat problem on the farm (RR 28.1). Cattle contact was associated with a significantly lower likelihood (protective) of glandular fever (RR 0.19) and rheumatic or scarlet fever (RR 0.12). These effects were significantly related to rankings of the extent of exposure. CONCLUSIONS--It is possible to recruit a representative sample of farmworkers and measure their animal exposures in great detail. Among these exposures, associations with plausible risk factors for pneumonia and leptospirosis and apparently protective factors for glandular fever, scarlet fever, and rheumatic fever have been demonstrated, which further show a relationship between the extent of exposure and response. These findings can be tested further by examining the relationship of exposures to serological evidence of illness or by further prospective follow up of this and similarly well characterised cohorts, or both. AD - Public Health Laboratory Service, Communicable Disease Surveillance Centre, Welsh Unit, Cardiff. PMID- 8189169 SO - J Epidemiol Community Health 1994 Apr;48(2):151-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 94312998 AU - de Caballero OL AU - Dias Neto E AU - Koury MC AU - Romanha AJ AU - Simpson AJ TI - Low-stringency PCR provides an internal control for negative results in PCR-based diagnosis. LA - Eng MH - Animal MH - Base Sequence MH - DNA, Bacterial/analysis MH - Hamsters MH - Infection/*diagnosis MH - Leptospira interrogans/genetics MH - Leptospirosis/diagnosis MH - Molecular Sequence Data MH - *Polymerase Chain Reaction MH - Reference Standards MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940822 DP - 1994 Apr IS - 1054-9803 TA - PCR Methods Appl PG - 305-7 SB - M CY - UNITED STATES IP - 5 VI - 3 JC - BNV EM - 9410 AD - Centro de Pesquisas Rene Rachou, FIOCRUZ, Minas Gerais, Brazil. PMID- 8038700 SO - PCR Methods Appl 1994 Apr;3(5):305-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [210 medline neighbors] UI - 94299827 AU - Savio ML AU - Rossi C AU - Fusi P AU - Tagliabue S AU - Pacciarini ML TI - Detection and identification of Leptospira interrogans serovars by PCR coupled with restriction endonuclease analysis of amplified DNA. LA - Eng MH - Animal MH - Base Sequence MH - Cloning, Molecular MH - DNA Primers MH - DNA Restriction Enzymes MH - DNA, Bacterial/genetics MH - Gene Amplification MH - Human MH - Leptospira interrogans/classification/*genetics/isolation & purification MH - Leptospirosis/diagnosis/microbiology MH - Molecular Sequence Data MH - Polymerase Chain Reaction/statistics & numerical data MH - Repetitive Sequences, Nucleic Acid MH - Sensitivity and Specificity MH - Serotyping MH - Support, Non-U.S. Gov't RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940805 DP - 1994 Apr IS - 0095-1137 TA - J Clin Microbiol PG - 935-41 SB - M CY - UNITED STATES IP - 4 VI - 32 JC - HSH AA - Author EM - 9410 AB - Primers for PCR were selected from a sequenced fragment of clone pL590, which contains a repetitive element present in the genome of Leptospira interrogans serovar hardjo type hardjoprajitno (M. L. Pacciarini, M. L. Savio, S. Tagliabue, and C. Rossi, J. Clin. Microbiol. 30:1243-1249, 1992). A specific DNA fragment was amplified from the genomic DNAs of serovar hardjo type hardjoprajitno and nine serovars also belonging to L. interrogans as a consequence of the spread of the same or a closely related repetitive element within this species (Pacciarini et al., J. Clin. Microbiol. 30:1243-1249, 1992). In addition, specific amplification was obtained from two Leptospira borgpetersenii serovars (tarassovi and hardjo type hardjobovis). Negative PCR results were observed with all of the other Leptospira serovars tested, including nonpathogenic ones (serovars patoc and andamana), another spirochete (Borrelia burgdorferi), bacteria commonly found in biological samples, and swine and bovine cell lines. Direct PCR on biological samples such as kidney samples demonstrated that preliminary isolation and culture of Leptospira cells are not required for efficient detection. Furthermore, digestion of the amplified DNA with the enzymes HinfI and DdeI yielded specific polymorphic patterns, allowing discrimination among the majority of the serovars. These methods were applied to 25 field isolates of serovar pomona, leading to the conclusion that they were suitable for the simple and rapid detection of L. interrogans and for serovar identification. AD - Instituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia, Brescia, Italy. PMID- 8027346 SI - GENBANK/X58829 SO - J Clin Microbiol 1994 Apr;32(4):935-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [189 medline neighbors] UI - 94299780 AU - Kee SH AU - Kim IS AU - Choi MS AU - Chang WH TI - Detection of leptospiral DNA by PCR. LA - Eng MH - Agglutination Tests MH - Animal MH - Base Sequence MH - DNA Primers/genetics MH - DNA, Bacterial/*genetics/isolation & purification MH - Evaluation Studies MH - Gerbillinae MH - Human MH - Leptospira interrogans/*genetics/isolation & purification MH - Leptospirosis/*diagnosis/microbiology MH - Molecular Sequence Data MH - Polymerase Chain Reaction/*methods/statistics & numerical data MH - Sensitivity and Specificity MH - Support, Non-U.S. Gov't RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940805 DP - 1994 Apr IS - 0095-1137 TA - J Clin Microbiol PG - 1035-9 SB - M CY - UNITED STATES IP - 4 VI - 32 JC - HSH AA - Author EM - 9410 AB - An EcoRI fragment (1.2 kb) which is highly conserved among Leptospira interrogans isolated in Korea was cloned into pBluescript vector from L. interrogans serovar lai WH20. The EcoRI fragment was sequenced, and a pair of primers (LP1 and LP2) was designed for PCR assay. PCR amplification of target DNA obtained from cultured L. interrogans showed that 274 bp could be detected when as little as 100 fg of leptospiral genomic DNA was used in the reaction mixture. No amplification of DNA was detected from DNA of Leptospira biflexa serovars patoc and sau paulo, Borrelia burgdorferi, Staphylococcus aureus, Escherichia coli, and Salmonella typhimurium. Amplification of 274-bp target DNA could be detected in DNA samples purified from 500 microliters of blood collected from experimentally infected gerbils 2 days after infection, while antibodies to L. interrogans could be detected by the microscopic agglutination test 7 days after infection. The specificity and high sensitivity of the test provided valuable tools for the early diagnosis of leptospirosis. AD - Department of Microbiology, Seoul National University College of Medicine, Republic of Korea. PMID- 8027306 SI - GENBANK/L13921 SO - J Clin Microbiol 1994 Apr;32(4):1035-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 95120020 AU - Iversson LB AU - da Rosa AP AU - Rosa MD AU - Lomar AV AU - Sasaki M da G AU - LeDuc JW TI - [Human infection by Hantavirus in southern and southeastern Brazil] LA - Por MH - Adult MH - Antibodies, Viral/analysis MH - Brazil MH - Case Report MH - English Abstract MH - Hantavirus/immunology MH - Hantavirus Infections/*diagnosis MH - Human MH - Male MH - Middle Age RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 950214 DP - 1994 Apr-Jun IS - 0104-4230 TA - Rev Assoc Med Bras PG - 85-92 CY - BRAZIL IP - 2 VI - 40 JC - BR5 AA - Author EM - 9504 AB - The results of serological investigation on Hantavirus antibodies carried out between February 1986 and August 1990 in human populations of the States of Sao Paulo and Parana, Brazil, which had close contact with urban rats or wild rodents and others small mammals are described. OBJECTIVE--To identify the human infection caused by Hantaviruses, which are the etiological agents of Hemorrhagic fever with renal syndrome. METHODS--Sera from 1063 persons were tested by enzyme immunoassay (ELISA) to Hantaan, Seoul and Puumala antigens. Plaque reduction neutralization test to the same antigens and indirect immunofluorescent test to Hantaan antigen were performed in the positive sera. RESULTS--Antibodies to Hantaan, Seoul or Puumala viruses were detected in 32 persons by enzyme immunoassay (ELISA) and immunofluorescent test. Plaque reduction neutralization test performed in these 32 sera were positive in 5 (3 for Puumala and 2 for Seoul viruses). One serum reacted with high titer to Seoul virus in all tests. It was from a male resident in the rural area of Ribeira Valley, State of Sao Paulo, where he was born and has always lived. He had only travelled inside the State of Sao Paulo. CONCLUSION--There are serological evidences of Hantavirus infections in residents of the rural areas of the Amparo Island, Paranagua Bay, State of Parana and the Ribeira Valley, State of Sao Paulo; in employees of the port of Paranagua, State of Parana and in patients of the Emilio Ribas Hospital, Sao Paulo, State of Sao Paulo, who had a presumptive diagnosis of leptospirosis. AD - Departamento de Epidemiologia da Faculdade de Saude Publica da Universidade de S. Paulo. PMID- 7820156 CU - 96 TT - Infeccao humana por Hantavirus no Sul e Sudeste do Brasil. EA - A SO - Rev Assoc Med Bras 1994 Apr-Jun;40(2):85-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 95113088 AU - Cacciapuoti B AU - Ciceroni L AU - Pinto A AU - Apollini M AU - Rondinella V AU - Bonomi U AU - Benedetti E AU - Cinco M AU - Dessi S AU - Dettori G AU - et al TI - Survey on the prevalence of leptospira infections in the Italian population. LA - Eng MH - Adult MH - Female MH - Health Surveys MH - Human MH - Italy/epidemiology MH - Leisure Activities MH - Leptospira/classification MH - Leptospirosis/blood/*epidemiology/microbiology/prevention & control/transmission MH - Male MH - Mass Screening/methods MH - *Population Surveillance MH - Prevalence MH - Residence Characteristics MH - Risk Factors MH - Rural Population MH - Seroepidemiologic Methods MH - Serotyping MH - Urban Population PT - JOURNAL ARTICLE DA - 950209 DP - 1994 Apr IS - 0392-2990 TA - Eur J Epidemiol PG - 173-80 SB - M CY - NETHERLANDS IP - 2 VI - 10 JC - ERE AA - Author EM - 9504 AB - This investigation is the first nationwide survey on the circulation of leptospira infections in human beings in Italy. In nine out of twenty Italian regions, representative samples of the population were investigated for the presence of leptospira infections. Unexpectedly, leptospira infections were found to be widespread, the number of cases being much higher than the diagnosed clinical cases. There were found to be high, medium, and low risk areas. On the whole, the risk for the rural population was no higher than the risk for urban dwellers; leisure activities, contact with animals and residence on the plain versus residence in the hills were important risk factors. There was an unidentified risk factor in urbanites which was absent in the rural population. A changing pattern in infecting serovars was observed, with infections from serogroups Sejroe, Javanica and Australis prevailing over infections from the Icterohaemorrhagiae and Bataviae serogroups, which were the main agents of human leptospirosis during the 1950s. The mechanisms of these changes, the need for epidemiological surveys and improved diagnostic methods of screening are discussed. AD - National Center for Leptospirosis, Istituto Superiore di Sanita, Rome, Italy. PMID- 7813695 SO - Eur J Epidemiol 1994 Apr;10(2):173-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [68 medline neighbors] UI - 95099690 AU - Greene CE TI - Diagnosis, therapy, and prevention of common infectious diseases in the dog. LA - Eng MH - Animal MH - Bronchitis/diagnosis/therapy/veterinary MH - Communicable Diseases/diagnosis/therapy/*veterinary MH - Coronavirus Infections/diagnosis/therapy/veterinary MH - Distemper/diagnosis/prevention & control/therapy MH - Dog Diseases/*diagnosis/prevention & control/*therapy MH - Dogs MH - Hepatitis, Viral, Animal/diagnosis/therapy MH - Leptospirosis/veterinary MH - Parvoviridae Infections/diagnosis/therapy/veterinary MH - Rabies/veterinary PT - JOURNAL ARTICLE DA - 950126 DP - 1994 Apr IS - 0165-2176 TA - Vet Q PG - 2S-5S SB - M CY - NETHERLANDS VI - 16 Suppl 1 JC - XBT EM - 9503 AD - Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602. PMID- 7801458 SO - Vet Q 1994 Apr;16 Suppl 1:2S-5S ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 94256038 AU - Clark AM TI - Leptospira hardjo infection in sheep [letter] LA - Eng MH - Abortion, Veterinary/microbiology MH - Animal MH - Female MH - Leptospirosis/microbiology/*veterinary MH - Pregnancy MH - Sheep MH - Sheep Diseases/*microbiology PT - LETTER DA - 940627 DP - 1994 Mar 12 IS - 0042-4900 TA - Vet Rec PG - 283 SB - M CY - ENGLAND IP - 11 VI - 134 JC - XBS EM - 9409 PMID- 8197701 SO - Vet Rec 1994 Mar 12;134(11):283 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 96134056 AU - Wood JL TI - How important are leptospiral infections as a cause of equine disease? [editorial; comment] LA - Eng MH - Abortion, Veterinary/epidemiology/*microbiology MH - Animal MH - Female MH - Horse Diseases/epidemiology/*microbiology/prevention & control MH - Horses MH - Incidence MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Pregnancy PT - COMMENT PT - EDITORIAL DA - 960311 DP - 1994 Mar IS - 0425-1644 TA - Equine Vet J PG - 88 SB - M CY - ENGLAND IP - 2 VI - 26 JC - EJ9 EM - 9605 CM - Comment on: Equine Vet J 1994 Mar;26(2):105-8 PMID- 8575386 SO - Equine Vet J 1994 Mar;26(2):88 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 96134061 AU - Williams DM AU - Smith BJ AU - Donahue JM AU - Poonacha KB TI - Serological and microbiological findings on 3 farms with equine leptospiral abortions [see comments] LA - Eng MH - Abortion, Veterinary/epidemiology/*etiology MH - Animal MH - Antibodies, Bacterial/analysis/blood/immunology MH - Bacteriuria/microbiology MH - Comparative Study MH - Female MH - Horse Diseases/epidemiology/immunology/*microbiology MH - Horses MH - Incidence MH - Leptospira/classification/immunology/isolation & purification MH - Leptospirosis/complications/epidemiology/*veterinary MH - Pregnancy MH - Prevalence MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 960311 DP - 1994 Mar IS - 0425-1644 TA - Equine Vet J PG - 105-8 SB - M CY - ENGLAND IP - 2 VI - 26 JC - EJ9 AA - Author EM - 9605 AB - Blood and urine samples from horses on 3 central Kentucky horse farms with prior histories of leptospiral abortions were analysed. Blood samples were obtained from all available horses on each farm and tested for antibodies to 6 leptospira serovars. Urine samples were collected from non-gravid mares with serum antibody titres > or = 1:800 and examined for leptospires by dark-field microscopy, fluorescent antibody testing and culture. Adult horses had the greatest serological evidence of exposure to leptospira, followed by yearlings, then foals. Of horses with anti-leptospiral antibodies, 76.3% reacted against serovar bratislava, 49.1% against icterohaemorrhagiae, 20.1% against grippotyphosa, 16.3% against pomona genotype kennewicki, 15.9% against hardjo and 1.0% against canicola. These findings confirmed that horses in central Kentucky are exposed to multiple leptospira serovars. The seroprevalence of antibodies to the 6 selected serovars was consistent among the 3 selected farms. There was no direct correlation between the serovar that was the cause of abortion in the previous season and prevalence of positive titres to that serovar in horses tested on the farms in the following year. Furthermore, there was no evidence of long- term urinary shedding of leptospira by horses with high leptospira antibody titres. AD - Department of Veterinary Science, University of Kentucky, Lexington 40511, USA. CM - Comment in: Equine Vet J 1994 Mar;26(2):88 PMID- 8575369 SO - Equine Vet J 1994 Mar;26(2):105-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 94281485 AU - Santiago Guervos M AU - Martin J AU - Paraiso V AU - Fidalgo A AU - Chacon JC TI - [Reflections of leptospirosis in Spain. Apropos of a case (letter)] LA - Spa MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*diagnosis/epidemiology MH - Male MH - Spain/epidemiology PT - LETTER DA - 940725 DP - 1994 Mar IS - 0212-7199 TA - An Med Interna PG - 151-2 CY - SPAIN IP - 3 VI - 11 JC - A5E EM - 9409 PMID- 8011881 TT - Reflexiones sobre la leptospirosis en Espana. A proposito de un caso. SO - An Med Interna 1994 Mar;11(3):151-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 95090359 AU - Martinelli R AU - Luna MA AU - Rocha H TI - Is rhabdomyolysis an additional factor in the pathogenesis of acute renal failure in leptospirosis? LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Female MH - Human MH - Kidney Failure, Acute/*etiology MH - Male MH - Middle Age MH - Myoglobin/blood MH - Prospective Studies MH - Rhabdomyolysis/blood/*complications MH - Support, Non-U.S. Gov't MH - Weil's Disease/*complications RN - 0 (Myoglobin) PT - JOURNAL ARTICLE DA - 950117 DP - 1994 Mar-Apr IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 111-4 CY - BRAZIL IP - 2 VI - 36 JC - S9D AA - Author EM - 9503 AB - Leptospirosis is an important cause of acute renal failure in our environment. Although several mechanisms are implicated, the role of rhabdomyolysis in the pathogenesis of acute renal failure in leptospirosis has not been analysed. Sixteen patients with the diagnosis of leptospiroses consecutively admitted to the hospital were prospectively studied. The disease was characterized by sudden onset in all patients and, at admission, jaundice, conjunctival suffusion and myalgias. Mild to moderate proteinuria with unremarkable urinary sediment was recorded in 37.5% of the patients and abnormal levels of urea creatinine were found in 87.5% and 74.0%, respectively. Increased levels of aminotranspherase were documented in all 12 and CPK in all 10 patients studied. Serum myoglobin levels greater than 120 micrograms/l recorded in 56.2%. A correlation between myoglobin and renal failure or severity of disease, however, could not be established. AD - Departamento de Medicina-Faculdade de Medicina, Universidade Federal da Bahia, Salvador, Brasil. PMID- 7997784 SO - Rev Inst Med Trop Sao Paulo 1994 Mar-Apr;36(2):111-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 95085564 AU - Muller H AU - Winkler P TI - [Results of serological studies of Leptospira antibodies in foxes] LA - Ger MH - Animal MH - Antibodies, Bacterial/*blood MH - English Abstract MH - *Foxes MH - Germany/epidemiology MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Seroepidemiologic Methods RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950109 DP - 1994 Mar IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 90-3 CY - GERMANY IP - 3 VI - 107 JC - 9Q8 AA - Author EM - 9503 AB - 1253 serum samples of foxes were checked for the presence of Leptospira antibodies. 24 serum samples (1.92%) were positive. Leptospira grippotyphosa (10 samples) was the most common serotype, which ist also widespread in other wild and domestic animals. The possibility of distribution of Leptospira in fox populations are discussed. Leptospira antibodies were found in only 0.20% of the examined serum samples of domestic animals of the same territory (South-Thuringia). AD - Medizinal-, Lebensmittel- und Veterinaruntersuchungsamt Thuringen. PMID- 7993345 TT - Ergebnisse serologischer Untersuchungen auf Leptospira-Antikorper bei Fuchsen. EA - A SO - Berl Munch Tierarztl Wochenschr 1994 Mar;107(3):90-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 94249790 AU - Gerritsen MJ AU - Koopmans MJ AU - Dekker TC AU - De Jong MC AU - Moerman A AU - Olyhoek T TI - Effective treatment with dihydrostreptomycin of naturally infected cows shedding Leptospira interrogans serovar hardjo subtype hardjobovis. LA - Eng MH - Amoxicillin/therapeutic use MH - Animal MH - Blood/microbiology MH - Case Report MH - Cattle MH - *Cattle Diseases MH - Dihydrostreptomycin Sulfate/*therapeutic use MH - Female MH - Human MH - Leptospira interrogans/classification/*isolation & purification MH - Male MH - Polymerase Chain Reaction MH - Sensitivity and Specificity MH - Support, Non-U.S. Gov't MH - Urine/microbiology MH - Weil's Disease/blood/*drug therapy/*veterinary RN - 26787-78-0 (Amoxicillin) RN - 5490-27-7 (Dihydrostreptomycin Sulfate) PT - JOURNAL ARTICLE DA - 940621 DP - 1994 Mar IS - 0002-9645 TA - Am J Vet Res PG - 339-43 SB - M CY - UNITED STATES IP - 3 VI - 55 JC - 40C AA - Author EM - 9408 AB - The efficacy of dihydrostreptomycin in stopping the shedding of Leptospira hardjo subtype hardjobovis was studied in naturally infected cows. Blood and urine samples were collected from dairy cows kept on a farm where the farmer had contracted L hardjobovis infection. A microscopic agglutination test and an ELISA were used to determine specific antibody responses in serum. Polymerase chain reaction was used to detect bacterial shedding in urine. On the first sample collection date, 6 cows were seropositive, and 3 of those shed leptospires in the urine. These 3 cows were treated once with 25 mg of dihydrostreptomycin/kg of body weight. Within 1 week, the 3 cows stopped shedding leptospires. Six weeks later, 8 more lactating cows were found to be shedding leptospires. These cows were also treated once with dihydrostreptomycin, and they too stopped shedding leptospires within 1 week. From then on, the whole herd was examined weekly for a period of 2 months, and all cows Leptospira-positive by polymerase chain reaction were treated once with dihydrostreptomycin. Again, all cows stopped shedding leptospires in the urine within 1 week after treatment with dihydrostreptomycin. After a single treatment of the whole herd at the same time, new infections were not seen. AD - Department of Bacteriology, Central Veterinary Institute, Lelystad, The Netherlands. PMID- 7514850 CU - 95 SO - Am J Vet Res 1994 Mar;55(3):339-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 94188054 AU - Bedernjak J TI - [Leptospirosis in Pomurje and Slovenia] LA - Hun MH - English Abstract MH - Female MH - Human MH - Hungary/epidemiology MH - Leptospira/classification MH - Leptospirosis/*epidemiology MH - Male MH - Serotyping MH - Slovenia/epidemiology MH - Weil's Disease/*epidemiology/immunology/mortality PT - JOURNAL ARTICLE DA - 940426 DP - 1994 Feb 20 IS - 0030-6002 TA - Orv Hetil PG - 409-11 CY - HUNGARY IP - 8 VI - 135 JC - OL8 AA - Author EM - 9406 AB - In Pomurje leptospirosis is endemic. During the years 1964-1985 there were 407 leptospiral cases reported in Slovenia, 366 of which were in Pomurje. Inclusion in this study required indication of leptospirae with a fourfold increase of the titer of antibodies or the isolation of leptospirae from hemocultures. In Pomurje in this period 214 men (58.47%) and 152 women (41.53%) were infected. The average morbidity rate was 12.75/100,000 inhabitants. The highest rate was in the country of Lendava (23.14/100,000). Ten serotypes were confirmed: grippotyphosa in 122 (33.33%) of the patients, sejroe in 91 (24.86%), icterohaemorrhagie in 50 (13.66%), saxkoebing in 48 (13.11%), australis in 47 (12.84%), canicola and pomona in two cases, tarassovi and autumnalis in one patient. In one case, the serotype could not be differentiated. The disease occurs throughout the years. In contrast to Western Europe in Pomurje there exists a much larger percent of infected women and a high percentage among the elderly. Two patients have died (mortality rate is 0.55%). One of them succumbed on the 5th day of infection due to massive bleeding in the heart and other organs. The other died on the 12th day under the influence of a severe Weil's syndrome. AD - Muraszombati Altalanos Korhaz Fertozo Osztaly, Murska Sobota, Szlovenia. PMID- 8139844 TT - Leptospirozis a Muravideken es Szloveniaban. EA - A SO - Orv Hetil 1994 Feb 20;135(8):409-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [85 medline neighbors] UI - 94158413 AU - Grandien M AU - Engvall A TI - [Quarantine to be abolished for dogs and cats. New regulations for import of pets from EU/EFTA countries] LA - Swe MH - Animal MH - *Cats MH - *Dogs MH - English Abstract MH - Europe/epidemiology MH - Human MH - *Quarantine/legislation & jurisprudence MH - Rabies/epidemiology/prevention & control/transmission MH - Sweden/epidemiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 940329 DP - 1994 Feb 2 IS - 0023-7205 TA - Lakartidningen PG - 373-4 CY - SWEDEN IP - 5 VI - 91 JC - L0N AA - Author EM - 9406 AB - Owing to its natural geographical borders and strict import restrictions, Sweden has remained free from rabies since 1886. New regulations are to come into force on May 1st, 1994, permitting pet dogs and cats from EU-EFTA countries to enter Sweden without quarantine, but only after vaccination against rabies and subsequent antibody titre control. Dogs should be at least three months old before vaccination, and cats 14 months old. Antibody titres are to be tested no earlier than four months after vaccination, though in cases of re- vaccination they may be checked already after one month for dogs and after four months for cats. The rabies antibody titre should be at least 0.5 IU to permit entry of the animal into Sweden. The owner will be required to show a Swedish import permit at customs, and some means of identifying the animal will be necessary--e.g., a tattoo in the ear. Other zoonoses could also be introduced into the country by imported animals, the most feared being echinococcosis and leptospirosis. The new regulations stipulate that, in addition to being vaccinated against canine distemper, dogs should also have been vaccinated against leptospirosis less than 12 months before entry in Sweden. This does not apply to cats, but both dogs and cats should have been dewormed less than ten days before entry or re-entry into Sweden. Although the new system should effectively prevent the introduction of rabies into Sweden, an increased demand by the public for information and advice is expected.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Virologiska enheten, Smittskyddsinstitutet, Stockholm. PMID- 8114565 TT - Karantan slopas for hund och katt. Nya regler for inforsel fran EU/EFTA- landerna. EA - A SO - Lakartidningen 1994 Feb 2;91(5):373-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 94224709 AU - Vaughan C AU - Cronin CC AU - Walsh EK AU - Whelton M TI - The Jarisch-Herxheimer reaction in leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Antibiotics/*adverse effects MH - Case Report MH - Female MH - Fever/*etiology MH - Human MH - Hypotension/*etiology MH - Leptospirosis/*drug therapy/physiopathology MH - Male MH - Pulse RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 940527 DP - 1994 Feb IS - 0032-5473 TA - Postgrad Med J PG - 118-21 SB - M CY - ENGLAND IP - 820 VI - 70 JC - PFX AA - Author EM - 9408 AB - Three patients with leptospirosis whose condition worsened after initiation of antibiotic therapy are reported. Their clinical deterioration appeared to be due to the development of the Jarisch- Herxheimer reaction rather than to progression of their underlying infection. Relevant aspects of the management of patients with leptospirosis are discussed. AD - Cork Regional Hospital, Department of Medicine, Wilton, Ireland. PMID- 8170883 SO - Postgrad Med J 1994 Feb;70(820):118-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 94220007 AU - Watson AD TI - Leptospirosis in cats and dogs [letter; comment] LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Cat Diseases/*prevention & control MH - Cats MH - Dog Diseases/*prevention & control MH - Dogs MH - Leptospira interrogans/*immunology MH - Leptospirosis/prevention & control/*veterinary MH - Vaccination/veterinary RN - 0 (Bacterial Vaccines) PT - COMMENT PT - LETTER DA - 940526 DP - 1994 Feb IS - 0005-0423 TA - Aust Vet J PG - 59-60 SB - M CY - AUSTRALIA IP - 2 VI - 71 JC - 9IE EM - 9407 CM - Comment on: Aust Vet J 1993 Oct;70(10):389-90 RO - M:LC2 PMID- 8166619 LR - 940727 SO - Aust Vet J 1994 Feb;71(2):59-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 94148767 AU - Zuerner RL AU - Stanton TB TI - Physical and genetic map of the Serpulina hyodysenteriae B78T chromosome. LA - Eng MH - Bacterial Proteins/genetics MH - Base Sequence MH - *Chromosome Mapping MH - *Chromosomes, Bacterial MH - DNA Topoisomerase (ATP-Hydrolysing)/genetics MH - DNA, Ribosomal/genetics MH - Flagella MH - Genes, Bacterial/*genetics MH - Genome, Bacterial MH - Hemolysins/genetics MH - Molecular Sequence Data MH - Multienzyme Complexes/genetics MH - Nucleic Acid Hybridization MH - NADH, NADPH Oxidoreductases/genetics MH - Restriction Mapping MH - RNA, Ribosomal/genetics MH - Serpulina hyodysenteriae/*genetics RN - EC 1.6. (NADH, NADPH Oxidoreductases) RN - EC 1.6.- (NADH2 oxidase) RN - EC 5.99.1.3 (DNA Topoisomerase (ATP-Hydrolysing)) RN - 0 (Bacterial Proteins) RN - 0 (DNA, Ribosomal) RN - 0 (Hemolysins) RN - 0 (Multienzyme Complexes) RN - 0 (RNA, Ribosomal) RN - 133606-66-3 (flaA protein) RN - 148711-15-3 (FlaB2 protein) PT - JOURNAL ARTICLE DA - 940321 DP - 1994 Feb IS - 0021-9193 TA - J Bacteriol PG - 1087-92 SB - M CY - UNITED STATES IP - 4 VI - 176 JC - HH3 AA - Author EM - 9405 AB - A combined physical and genetic map of the Serpulina hyodysenteriae B78T genome was constructed by using pulsed-field gel electrophoresis and DNA blot hybridizations. The S. hyodysenteriae genome is a single circular chromosome about 3.2 Mb in size. The physical map of the chromosome was constructed with the restriction enzymes BssHII, EclXI, NotI, SalI, and SmaI. The physical map was used to constructed a linkage map for genes encoding rRNA, flagellum subunit proteins, DNA gyrase, NADH oxidase, and three distinct hemolysins. Several flaB2- related loci, encoding core flagellum subunit proteins, were detected and are dispersed around the chromosome. The rRNA gene organization in S. hyodysenteriae is unusual. S. hyodysenteriae has one gene each for 5S (rrf), 16S (rrs), and 23S (rrl) rRNAs. The rrf and rrl genes are closely linked (within 5 kb), while the rrs gene is about 860 kb from the other two rRNA genes. Using a probe for the S. hyodysenteriae gyrA gene, we identified a possible location for the chromosomal replication origin. The size and genetic organization of the S. hyodysenteriae chromosome are different from those of previously characterized spirochetes. AD - Leptospirosis and Mycobacteriosis Research Unit, U.S. Department of Agriculture, Ames, Iowa 50010. PMID- 8106320 CU - 95 SO - J Bacteriol 1994 Feb;176(4):1087-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 94353738 AU - Berezovskaia ZB AU - Mishchuk II AU - Ossovskaia AB AU - Kochetova MV AU - Poberezhets SIu AU - Avdashkova IA TI - [The characteristics of the course and treatment of severe forms of leptospirosis] LA - Rus MH - Acute Disease MH - Combined Modality Therapy MH - English Abstract MH - Epistaxis/diagnosis/etiology/therapy MH - Gastrointestinal Hemorrhage/diagnosis/etiology/therapy MH - Human MH - Kidney Failure/diagnosis/etiology/therapy MH - Leptospirosis/complications/*diagnosis/therapy MH - Liver Failure/diagnosis/etiology/therapy PT - JOURNAL ARTICLE DA - 940929 DP - 1994 Feb IS - 1019-5297 TA - Lik Sprava PG - 84-5 CY - UKRAINE IP - 2 JC - CIU AA - Author EM - 9412 AB - At the resuscitation clinic 27 patients suffering from hepatorenal form of leptospirosis were observed. Some features of the course of hepatorenal insufficiency were noted in this disease: relatively short period of oligoanuria, absence of hyperkalemia, dependence of the degree of hemorrhagic syndrome on the level of thrombocytes and absence of correlation with prothrombin consumption index, an apparent brain edema in autopsy tissue. Timely delivery of intensive care including hemodialysis, hemosorption, oxybarotherapy, ultraviolet irradiation of blood, corticosteroid therapy enabled the recovery to be secured in 67% of patients with grave forms of leptospirosis. PMID- 8073731 CU - 96 TT - Nekotorye osobennosti techeniia i lecheniia tiazhelykh form leptospiroza. EA - A SO - Lik Sprava 1994 Feb;(2):84-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 95090401 AU - de Almeida LP AU - Martins LF AU - Brod CS AU - Germano PM TI - [Seroepidemiologic survey of leptospirosis among environmental sanitation workers in an urban locality in the southern region of Brazil] LA - Por MH - Brazil/epidemiology MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - *Occupations/standards MH - Prevalence MH - Seroepidemiologic Methods MH - *Urban Population PT - JOURNAL ARTICLE DA - 950117 DP - 1994 Feb IS - 0034-8910 TA - Rev Saude Publica PG - 76-81 CY - BRAZIL IP - 1 VI - 28 JC - T5X AA - Author EM - 9503 AB - Sera from 386 environmental sanitation workers, concerned with water supply, drains and drainage galleries, sewers, garbage collection and road sweepers, were examined for leptospiral agglutinins by the microscopic agglutination test. Altogether 40 of the 386 workers (10.4%) were positive to one or more serovars; however, the difference in seropositivity between the professional categories was not significant (p < 0.05). Twelve serovars were recorded among the seropositive workers with predominance of L. castelonis and L. australis; but the difference between the serovars was not statistically significant (p > 0.05). Of the seropositive workers, 86.9% had agglutination titres > or = 100 and < or = 400; the rates for titres 100 and 400 were higher than 800, 1,600 and 3,200 (p < 0.05). AD - Faculdade de Saude Publica da Univesidade de Sao Paulo, Brasil. PMID- 7997826 TT - Levantamento soroepidemiologico de leptospirose em trabalhadores do servico de saneamento ambiental em localidade urbana da regiao sul do Brasil. EA - A SO - Rev Saude Publica 1994 Feb;28(1):76-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 94227802 AU - Vinh T AU - Faine S AU - Handley CJ AU - Adler B TI - Immunochemical studies of opsonic epitopes of the lipopolysaccharide of Leptospira interrogans serovar hardjo. LA - Eng MH - Antibodies, Bacterial/*immunology MH - Antibodies, Monoclonal/immunology MH - Epitopes/*immunology MH - Galactose/analysis MH - Leptospira interrogans/*immunology MH - Lipopolysaccharides/chemistry/*immunology MH - Mannosephosphates/analysis MH - Oligosaccharides/chemistry MH - Opsonins/*immunology MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Epitopes) RN - 0 (Lipopolysaccharides) RN - 0 (Mannosephosphates) RN - 0 (Oligosaccharides) RN - 0 (Opsonins) RN - 26566-61-0 (Galactose) RN - 3672-15-9 (mannose-6-phosphate) PT - JOURNAL ARTICLE DA - 940603 DP - 1994 Feb IS - 0928-8244 TA - FEMS Immunol Med Microbiol PG - 99-107 SB - M CY - NETHERLANDS IP - 2 VI - 8 JC - BP1 AA - Author EM - 9408 AB - Leptospiral lipopolysaccharides (LPS) are the main antigens responsible for immunity in leptospirosis. In this investigation we studied the nature of the antigenic determinants of LPS extracted from Leptospira interrogans serovar hardjo (reference strain Hardjoprajitno). The reactions of anti-LPS monoclonal antibodies (mAbs) MUM/F1-4/hardjo (IgM) and MUM/F1-6/hardjo (IgG) with whole cell lysates in Western immunoblotting analysis were unaffected by proteinase K treatment. Periodate treatment of the LPS destroyed the binding of MUM/F1-6/hardjo but preserved that of MUM/F1-4/hardjo. Alkaline phosphatase decreased significantly the binding of MUM/F1-4/hardjo to the LPS but only slightly that of MUM/F1-6/hardjo. On the other hand, phosphodiesterase totally destroyed the binding capacity of both monoclonal antibodies in enzyme immunoassays (EIA). A number of mono- and oligosaccharides was used in EIA inhibition studies. Mannose-6-phosphate and galactose-6- phosphate inhibited the binding of MUM/F1-4/hardjo (50% inhibition at a concentration of 5 mM) to the antigen, but glucose-6-phosphate did not. Galactosamine and mannosamine inhibited the binding of MUM/F1-6/hardjo (50% inhibition at a concentration of 3-4 mM), whereas only a weak inhibition was observed with glucosamine. In contrast, N-acetylated amino sugars did not show any inhibition. An O-acetyl group also appears to be involved in the antigen-antibody binding process. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 7513591 CU - 95 SO - FEMS Immunol Med Microbiol 1994 Feb;8(2):99-107 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 94121126 AU - Levin N AU - Nguyen-Khoa JL AU - Charpentier D AU - Strobel M AU - Fournie-Amazouz E AU - Denis P TI - Panuveitis with papillitis in leptospirosis [letter] LA - Eng MH - Case Report MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*complications/diagnosis MH - Male MH - Middle Age MH - *Optic Disk MH - Optic Neuritis/etiology MH - Panuveitis/*etiology MH - Retinal Diseases/etiology MH - Vasculitis/etiology PT - LETTER DA - 940222 DP - 1994 Jan 15 IS - 0002-9394 TA - Am J Ophthalmol PG - 118-9 SB - A SB - M CY - UNITED STATES IP - 1 VI - 117 JC - 3OQ EM - 9404 PMID- 8291582 SO - Am J Ophthalmol 1994 Jan 15;117(1):118-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 94267732 AU - Yukawa M AU - Kamata H AU - Ohba S AU - Kadoi K AU - Mochizuki K TI - Effect of immune serum, an antibiotic, and a corticosteroid used alone or in combination on experimental leptospirosis in Mongolian gerbils (Meriones unguiculatus). LA - Eng MH - Adrenal Cortex Hormones/*therapeutic use MH - Animal MH - Antibiotics/*therapeutic use MH - Combined Modality Therapy MH - Drug Therapy, Combination MH - Gerbillinae MH - *Immune Sera MH - Leptospirosis/mortality/pathology/*therapy MH - Male MH - Treatment Outcome RN - 0 (Adrenal Cortex Hormones) RN - 0 (Antibiotics) RN - 0 (Immune Sera) PT - JOURNAL ARTICLE DA - 940712 DP - 1994 IS - 0233-111X TA - J Basic Microbiol PG - 49-55 SB - M CY - GERMANY IP - 1 VI - 34 JC - JOT AA - Author EM - 9409 AB - We studied the effects of immune sera, an antibiotic, and a corticosteroid used alone or in combination on leptospira infection in Mongolian gerbils (Meriones unguiculatus). The results suggest that the combined used of immune serum and corticosteroid (pledonizoron: PZ) inhibits the effects of serum and the marked effects of antibiotic (procaine penicillin-G: PC-G) on leptospirosis. PZ had no effects and rather shortened the survival period. PZ did not affect the effects of PC-G when used in combination. These results suggest that treatment of leptospirosis with corticosteroids requires special caution. AD - Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Nihon University, Kanagawa, Japan. PMID- 8207664 SO - J Basic Microbiol 1994;34(1):49-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 protein link] [1 nucleotide link] [188 medline neighbors] UI - 94224974 AU - Zuerner RL TI - Nucleotide sequence analysis of IS1533 from Leptospira borgpetersenii: identification and expression of two IS-encoded proteins. LA - Eng MH - Amino Acid Sequence MH - Bacterial Proteins/biosynthesis/*genetics MH - Base Sequence MH - Cloning, Molecular MH - Comparative Study MH - *DNA Insertion Elements MH - Introns MH - Leptospira/*genetics/metabolism MH - Molecular Sequence Data MH - Mutagenesis, Insertional MH - Oligodeoxyribonucleotides MH - Open Reading Frames MH - *Plasmids MH - Repetitive Sequences, Nucleic Acid MH - Restriction Mapping MH - RNA, Messenger/biosynthesis/metabolism MH - Sequence Homology, Amino Acid MH - Sequence Homology, Nucleic Acid MH - Terminator Regions (Genetics) MH - Transcription, Genetic MH - Translation, Genetic RN - 0 (Bacterial Proteins) RN - 0 (DNA Insertion Elements) RN - 0 (Oligodeoxyribonucleotides) RN - 0 (Plasmids) RN - 0 (RNA, Messenger) PT - JOURNAL ARTICLE DA - 940601 DP - 1994 Jan IS - 0147-619X TA - Plasmid PG - 1-11 SB - M CY - UNITED STATES IP - 1 VI - 31 JC - P8P AA - Author EM - 9408 AB - The nucleotide sequence of IS1533, an insertion sequence-like element cloned from the spirochete Leptospira borgpetersenii, was determined. IS1533 contains imperfect terminal inverted repeats (IVR) of 31 bp flanking a 1402-bp internal sequence. A putative target sequence was identified, and insertion may result in duplication of 2 bp. The internal sequence has a single open reading frame (ORF). IS1533 encodes two proteins (43.5 and 41 kDa) initiating alternatively at either the first or the second AUG codons of the ORF. These proteins are related to a recently recognized family of IS-encoded transposases and bacterial recombinases, all which share a region of homology with the active site of the HIV reverse transcriptase. The IS1533-encoded proteins were expressed in Escherichia coli. Both the 43.5- and 41-kDa proteins bound IS1533 DNA probes in a Southwestern blot assay. These data suggest that one or both proteins function during transposition of IS1533. AD - Leptospirosis and Mycobacteriosis Research Unit, U.S. Department of Agriculture, National Animal Disease Center, Ames, Iowa 50010. PMID- 8171119 SI - GENBANK/M82880 SO - Plasmid 1994 Jan;31(1):1-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [67 medline neighbors] UI - 94202341 AU - New JC Jr AU - Delozier K AU - Barton CE AU - Morris PJ AU - Potgieter LN TI - A serologic survey of selected viral and bacterial diseases of European wild hogs, Great Smoky Mountains National Park, USA. LA - Eng MH - Animal MH - Animals, Wild MH - Antibodies, Bacterial/*blood MH - Antibodies, Viral/*blood MH - Brucella/immunology MH - Brucellosis/epidemiology/*veterinary MH - Diarrhea Virus, Bovine Viral/immunology MH - Female MH - Herpesvirus 1, Suid/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/veterinary MH - Male MH - Parvoviridae/immunology MH - Parvoviridae Infections/epidemiology/veterinary MH - Prevalence MH - Pseudorabies/*epidemiology MH - Rotavirus/immunology MH - Swine MH - Swine Diseases/*epidemiology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 940510 DP - 1994 Jan IS - 0090-3558 TA - J Wildl Dis PG - 103-6 SB - M CY - UNITED STATES IP - 1 VI - 30 JC - KEM AA - Author EM - 9407 AB - Blood samples were collected from 108 wild hogs (Sus scrofa) from the Great Smoky Mountains National Park (GSMNP), USA, February to July 1990. We found no antibodies for swine brucellosis, pseudorabies, bovine virus diarrhea virus or porcine rotavirus infection. Antibody titers to porcine parvovirus were found in 15 (14%) samples and antibody to one or more leptospiral serovars was found in 48 (44%) samples. Thirty-nine (89%) of the 44 positive samples reacted to all five leptospiral serovars tested. AD - Department of Environmental Practice College of Veterinary Medicine, University of Tennessee, Knoxville 37901-1071. PMID- 8151810 SO - J Wildl Dis 1994 Jan;30(1):103-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 94180924 AU - Samsonova AP AU - Anan'ina IuV AU - Aksenov MIu AU - Savel'eva OV AU - Gintsburg AL TI - [A polymerase chain reaction method for studying host persistence of pathogenic leptospira] LA - Rus MH - Acute Disease MH - Animal MH - Brain/microbiology MH - Chronic Disease MH - English Abstract MH - Hamsters MH - Kidney/microbiology MH - Leptospira interrogans/genetics/*isolation & purification/pathogenicity MH - Leptospirosis/diagnosis MH - Liver/microbiology MH - Mesocricetus MH - Polymerase Chain Reaction MH - Sensitivity and Specificity PT - JOURNAL ARTICLE DA - 940419 DP - 1994 Jan-Feb IS - 0208-0613 TA - Mol Gen Mikrobiol Virusol PG - 19-23 SB - M CY - RUSSIA IP - 1 JC - NMJ AA - Author EM - 9406 AB - Polymerase chain reaction has for the first time been shown to be applicable to indication of Leptospira interrogans in the organs of infected animals with acute or chronic leptospirosis (on the model of golden syrian hamsters). Polymerase chain reaction is superior to microscopic and bacteriological analyses in identification of leptospirae in organ suspensions. The sensitivity of the technique is 1- 10 cells per sample in studies of kidney or brain suspensions or 100- 1000 cells in studies of liver suspensions. PMID- 8133845 TT - Metod polimeraznoi tsepnoi reaktsii v izuchenii gostal'noi persistentsii patogennykh leptospir. EA - A SO - Mol Gen Mikrobiol Virusol 1994 Jan-Feb;(1):19-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 94180923 AU - Samsonova AP AU - Aksenov MIu AU - Anan'ina IuV AU - Markova GA AU - Garovnikova IuS AU - Gintsburg AL TI - [Development of a test system for detecting Leptospira interrogans using the polymerase chain reaction] LA - Rus MH - DNA Primers MH - English Abstract MH - Leptospira interrogans/genetics/*isolation & purification MH - Leptospirosis/diagnosis MH - Polymerase Chain Reaction MH - Sensitivity and Specificity MH - Temperature RN - 0 (DNA Primers) PT - JOURNAL ARTICLE DA - 940419 DP - 1994 Jan-Feb IS - 0208-0613 TA - Mol Gen Mikrobiol Virusol PG - 15-9 SB - M CY - RUSSIA IP - 1 JC - NMJ AA - Author EM - 9406 AB - Based on polymerase chain reaction a test-system has been elaborated permitting one to identify the leptospirae of the most common serogroups (Icterohaemorrhagiae, Canicola, Javanica, Ballum, Pyrogenes, Pomona, Habdomadis, Sejroe, Tarassovi) of the species Leptospira interrogans. Sensitivity of the technique is 1-10 cells in a sample. The specificity of the system has been shown to depend on the temperature of the primers annealing. The elaborated system exceeds all other systems for leptospiral identification in sensitivity. It is prospective for leptospiral identification in biological liquids aimed at early diagnosis of leptospiroses and in the studies of leptospiral persistence in host organisms in the saprophitic phase of life cycle. PMID- 8133844 TT - Razrabotka test-sistemy dlia vyiavleniia Leptospira interrogans metodom polimeraznoi tsepnoi reaktsii. EA - A SO - Mol Gen Mikrobiol Virusol 1994 Jan-Feb;(1):15-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 94340747 AU - Arimitsu Y AU - Kmety E AU - Ananyina Y AU - Baranton G AU - Ferguson IR AU - Smythe L AU - Terpstra WJ TI - Evaluation of the one-point microcapsule agglutination test for diagnosis of leptospirosis. LA - Eng MH - Agglutination Tests/*methods MH - Comparative Study MH - Complement Fixation Tests MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Leptospira/classification/immunology MH - Leptospirosis/*diagnosis/microbiology MH - Sensitivity and Specificity MH - Serotyping PT - JOURNAL ARTICLE PT - MULTICENTER STUDY DA - 940916 DP - 1994 IS - 0042-9686 TA - Bull World Health Organ PG - 395-9 CY - SWITZERLAND IP - 3 VI - 72 JC - C80 AA - Author EM - 9411 AB - We have developed a one-point microcapsule agglutination test (MCAT) for the serodiagnosis of leptospirosis. The MCAT kit was evaluated for use in humans by six WHO Collaborating Centres for Reference and Research on Leptospirosis. The laboratories classified their serum samples on the basis of the microscopic agglutination test (MAT) and the following screening tests: enzyme-linked immunosorbent assay (ELISA), macroscopic (slide) agglutination test, or the complement fixation test. The MCAT may in some instances give a positive result earlier in the course of the disease than MAT or the ELISA IgM; on the other hand, it did not detect antibodies against some serovars, for example, those of the Sejroe or Australis serogroup in Slovakia. In contrast, however, the MCAT detected antibodies to serovar hardjo (the same serogroup as Sejroe) in patients from the United Kingdom and the Russian Federation. AD - Department of Bacteriology, National Institute of Health, Tokyo, Japan. PMID- 8062397 SO - Bull World Health Organ 1994;72(3):395-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 94313169 AU - Dhaliwal GS AU - Murray RD AU - Downham DY AU - Dobson H TI - The effect of vaccination against Leptospira interrogans serovar hardjo infection at the time of service on pregnancy rates in dairy cows. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Female MH - Fertility MH - Immunization, Secondary/veterinary MH - Leptospira interrogans/*immunology MH - Leptospirosis/prevention & control/*veterinary MH - Pregnancy MH - *Pregnancy, Animal MH - Vaccination/veterinary RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 940823 DP - 1994 IS - 0928-4249 TA - Vet Res PG - 271-4 SB - M CY - FRANCE IP - 2-3 VI - 25 JC - BR0 AA - Author EM - 9410 AB - Fertility data from 16 dairy herds vaccinated against hardjo infection were used to assess pregnancy rates in cattle vaccinated around the day of mating. There was no improvement in pregnancy rates 30-60 d after vaccination. Pregnancy rates in the period 5 d before and 10 d after vaccination were statistically lower than those found in 30-60 d around vaccination. AD - Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Leahurst, Neston, South Wirral, UK. PMID- 8038799 SO - Vet Res 1994;25(2-3):271-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 94310260 AU - Garcia-Arumi J AU - Salvador F AU - Corcostegui B AU - Mateo C TI - Neuroretinitis associated with melanocytoma of the optic disk. LA - Eng MH - Adult MH - Blindness/etiology MH - Case Report MH - Eye Neoplasms/*complications/pathology MH - Female MH - Fluorescein Angiography MH - Fundus Oculi MH - Human MH - Nevus, Pigmented/*complications/pathology MH - Optic Disk/*pathology MH - Optic Neuritis/*etiology MH - Papilledema/complications/etiology MH - Retinal Detachment/etiology MH - Retinitis/*etiology/pathology MH - Visual Acuity PT - JOURNAL ARTICLE DA - 940815 DP - 1994 IS - 0275-004X TA - Retina PG - 173-6 SB - M CY - UNITED STATES IP - 2 VI - 14 JC - R8R AA - Author EM - 9410 AB - BACKGROUND: Melanocytomas of the optic disk are heavily pigmented benign tumors that are most often discovered during routine examination, as they are classically asymptomatic. Although a slight impairment of visual acuity attributable to the tumor may occur in large tumors, acute profound visual loss is extremely unusual. METHODS: A case involving a 24-year-old woman with melanocytoma of the optic nervehead in the right eye, who experienced acute severe visual loss, an afferent pupillary defect, and optic nervehead edema, is discussed. Laboratory tests and serology for Toxoplasmosis, Syphilis, Borrelia, and Leptospira were performed. RESULTS: The severe loss of vision, optic disc swelling, exudative detachment of the peripapillary retina, macular star, and spontaneous resolution in an otherwise healthy patient were all consistent with Leber's stellate idiopathic neuroretinitis. Results of serologic testing were not contributory. CONCLUSION: This is the first report of Leber's neuroretinitis associated with melanocytoma of the optic nervehead, and should be included in the differential diagnosis of neuroretinitis. The possible mechanisms responsible for this association are discussed. AD - Department of Ophthalmology, Universidad Autonoma de Barcelona, Spain. PMID- 8036328 SO - Retina 1994;14(2):173-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [30 medline neighbors] UI - 94287631 AU - Eaglesome MD AU - Bielanski A AU - Hare WC AU - Ruhnke HL TI - Studies on inactivation of pathogenic microorganisms in culture media and in bovine semen by photosensitive agents. LA - Eng MH - Animal MH - Campylobacter fetus/drug effects MH - Cattle MH - Comparative Study MH - *Culture Media MH - Diarrhea Virus, Bovine Viral/drug effects MH - Hematoporphyrin Derivative/toxicity MH - Hematoporphyrins/toxicity MH - Herpesvirus 1, Bovine/drug effects MH - Leptospira/drug effects MH - *Light MH - Male MH - Mycoplasma/drug effects MH - Pyronine/analogs & derivatives/toxicity MH - Radiation-Sensitizing Agents/*toxicity MH - Semen/*microbiology MH - Support, Non-U.S. Gov't MH - Ureaplasma/drug effects RN - 0 (Culture Media) RN - 0 (Hematoporphyrins) RN - 0 (Radiation-Sensitizing Agents) RN - 2412-14-8 (thiopyronine) RN - 68335-15-9 (Hematoporphyrin Derivative) RN - 92-32-0 (Pyronine) PT - JOURNAL ARTICLE DA - 940725 DP - 1994 Jan IS - 0378-1135 TA - Vet Microbiol PG - 277-84 SB - M CY - NETHERLANDS IP - 3 VI - 38 JC - XBW AA - Author EM - 9409 AB - The application of three photosensitive agents for disinfection of bovine semen was investigated. Bovine microbial pathogens suspended in tissue culture medium and/or PBS and also added to bovine semen were exposed to the photosensitive agents followed by irradiation. Hematoporphyrin, hematoporphyrin derivative and thiopyronine were effective against bovine herpes virus-1, bovine viral diarrhoea virus, Mycoplasma bovigenitalium, Mycoplasma canadense, and Ureaplasma diversum in culture media. In addition, thiopyronine was effective against Leptospira pomona. Similar treatments were not effective against Leptospira hardjo, Mycoplasma bovis, or Campylobacter fetus subsp. venerealis. When microorganisms were added to bovine semen, only bovine herpes virus-1 was controlled by the photosensitive agents used at concentrations which did not appear harmful to sperm cells. AD - Agriculture Canada, Animal Diseases Research Institute, NEPEAN, Ont., Canada. PMID- 8017031 SO - Vet Microbiol 1994 Jan;38(3):277-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 94278170 AU - Cruz ML AU - Andrade J AU - Pereira MM TI - [Leptospirosis in children in Rio do Janeiro] LA - Por MH - Age Distribution MH - Antibodies, Bacterial/blood MH - Brazil/epidemiology MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Infant MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/epidemiology MH - Male MH - Retrospective Studies MH - Seroepidemiologic Methods MH - Sex Distribution MH - *Urban Population/statistics & numerical data RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940719 DP - 1994 Jan-Mar IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 5-9 CY - BRAZIL IP - 1 VI - 27 JC - RET AA - Author EM - 9409 AB - In order to obtain data about clinical manifestations of symptomatic leptospiral infection in children, the authors reviewed 188 microscopic agglutination tests performed on sera of patients aged 0 to 12 years, made at the National Reference Laboratory of Leptospirosis (FIOCRUZ-RJ) from January 1983 to June 1991. Fifty two (27.6%) sera were positive. Twenty three (12.2%) children had serological evidence of acute infection. The most frequent signs and symptoms of these 23 cases were: fever (100%); myalgia (69.5%); headache (52.1%); jaundice (47.8%); vomit (34.8%); abdominal pain, hemorrhagic manifestations and impaired renal function (17.4%); conjunctivitis (13%); hepatomegaly (4.3%). AD - Servico de Doencas Infecciosas e Parasitarias, Hospital dos Servidores do Estado, Rio de Janeiro, Brasil. PMID- 8008921 TT - Leptospirose em criancas no Rio de Janeiro. EA - A SO - Rev Soc Bras Med Trop 1994 Jan-Mar;27(1):5-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 94278168 AU - Neves E de S AU - Pereira MM AU - Galhardo MC AU - Caroli A AU - Andrade J AU - Morgado MG AU - Mendes RP TI - Leptospirosis patient with AIDS: the first case reported. LA - Eng MH - AIDS-Related Opportunistic Infections/*diagnosis/microbiology/pathology MH - Case Report MH - Fatal Outcome MH - Human MH - *HIV-1 MH - Kidney Failure/*diagnosis/microbiology/pathology MH - Leptospira interrogans/isolation & purification MH - Male MH - Weil's Disease/*diagnosis/microbiology/pathology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW OF REPORTED CASES DA - 940719 DP - 1994 Jan-Mar IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 39-42 CY - BRAZIL IP - 1 VI - 27 JC - RET AA - Author EM - 9409 AB - A case of renal icterohemorrhagic leptospirosis involving a patient with acquired immunodeficiency syndrome (AIDS) is reported. Despite the low levels of CD4+ T lymphocytes, the clinical course of leptospirosis was similar to that observed in non-immunodepressed patients, and no worsening of AIDS occurred due to the infection by the spirochete. Serologic conversion was observed in the microscopic agglutination test, with maximum titer of 1:3,200. The patient had positive urine cultures for Leptospira interrogans for two months, whereas blood cultures were negative. AD - Hospital Evandro Chagas, Department of Bacteriology, Instituto Oswaldo Cruz/Fundacao Oswaldo Cruz, Rio de Janeiro, Brasil. RF - 10 PMID- 8008919 SO - Rev Soc Bras Med Trop 1994 Jan-Mar;27(1):39-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 95090342 AU - Santoro ML AU - Kogika MM AU - Hagiwara MK AU - Mirandola RM AU - Castelar IL TI - Decreased erythrocyte osmotic fragility during canine leptospirosis. LA - Eng MH - Animal MH - Dog Diseases/blood/*microbiology/physiopathology MH - Dogs MH - Hemolysis MH - Leptospira interrogans MH - Osmotic Fragility/*physiology MH - Weil's Disease/blood/*veterinary PT - JOURNAL ARTICLE DA - 950117 DP - 1994 Jan-Feb IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 1-5 CY - BRAZIL IP - 1 VI - 36 JC - S9D AA - Author EM - 9503 AB - Erythrocyte osmotic fragility (EOF) was carried out in nineteen dogs naturally infected by Leptospira interrogans serovar icterohaemorrhagiae/copenhagi. A decreased EOF was observed, suggesting a modification of erythrocyte components secondary to disturbances that occur during canine leptospirosis, such as renal damage and hepatic disease. AD - Laboratory of Pathophysiology-Institute Butantan, Sao Paulo, Brazil. PMID- 7997768 SO - Rev Inst Med Trop Sao Paulo 1994 Jan-Feb;36(1):1-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 95072389 AU - Andreescu N TI - [Current practical aspects of the use of bacteriological and serological studies in the diagnosis of human leptospirosis] LA - Rum MH - Human MH - Leptospirosis/*diagnosis/microbiology MH - Serodiagnosis PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 950103 DP - 1994 Jan-Jun TA - Bacteriol Virusol Parazitol Epidemiol PG - 3-5 CY - ROMANIA IP - 1-2 VI - 39 JC - BFP EM - 9503 AD - Institutul Cantacuzino. RF - 5 PMID- 7981525 TT - Aspecte practice actuale in utilizarea investigatiilor bacteriologice si serologice pentru diagnosticul leptospirozelor umane. SO - Bacteriol Virusol Parazitol Epidemiol 1994 Jan-Jun;39(1-2):3-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [37 medline neighbors] UI - 95058301 AU - Haake DA AU - Lovett MA TI - Interjunctional invasion of endothelial cell monolayers. LA - Eng MH - Amnion/cytology/physiology MH - Borrelia burgdorferi/physiology/*pathogenicity MH - Cell Separation/methods MH - Cells, Cultured MH - *Chemotaxis MH - Electrophysiology/methods MH - Endothelium, Vascular/cytology/*microbiology/*physiology MH - Female MH - Human MH - Leptospira/physiology/*pathogenicity MH - Microscopy, Electron/methods MH - Pregnancy MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Support, U.S. Gov't, P.H.S. MH - Tissue Culture/methods MH - Treponema/physiology/*pathogenicity/ultrastructure MH - Treponema pallidum/physiology/pathogenicity/ultrastructure MH - Umbilical Veins PT - JOURNAL ARTICLE ID - AI-21352/AI/NIAID ID - AI-29733/AI/NIAID DA - 941206 DP - 1994 IS - 0076-6879 TA - Methods Enzymol PG - 447-63 SB - M CY - UNITED STATES VI - 236 JC - MVA EM - 9502 AD - Department of Medicine, West Los Angeles Veterans Administration Medical Center, California 90073. PMID- 7968629 SO - Methods Enzymol 1994;236:447-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 95040893 AU - Shubin MG AU - Abdeeva MG AU - Lebedev VV AU - Shmelev SI TI - [Characteristics of lymphocyte-monocyte-neutrophil interactions during varied-severity course of leptospirosis (a cytochemical study)] LA - Rus MH - Adolescence MH - Adult MH - Aged MH - Comparative Study MH - English Abstract MH - Female MH - Histocytochemistry MH - Human MH - Lymphocytes/*enzymology MH - Male MH - Middle Age MH - Monocytes/*enzymology MH - Neutrophils/*enzymology MH - Weil's Disease/*blood/enzymology PT - JOURNAL ARTICLE DA - 941129 DP - 1994 IS - 0869-2084 TA - Klin Lab Diagn PG - 25-7 CY - RUSSIA IP - 4 JC - B17 AA - Author EM - 9502 AB - Correlations between neutrophilic enzymes (acid and alkaline phosphatases, myeloperoxidase, NBT test) and lymphocyte and monocyte enzymes (acid phosphatase, nonspecific esterase) were studied in 110 patients with icterohemorrhagic leptospirosis. These correlations were changing, depending on the disease severity and period. In case of a favorable course of leptospirosis in the initial period and at the peak a great number of intercellular correlations are formed between neutrophilic, lymphocytic, and monocytic enzymes. If the disease course is grave and complicated the intercellular relationships are ruptured at the peak of the illness. Convalescence is characterized by a gradual recovery of intracellular correlations. PMID- 7953106 TT - Osobennosti limfotsito-monotsito-neitrofil'nykh vzaimodeistvii pri raznoi tiazhesti techeniia leptospiroza (tsitokhimicheskoe issledovanie). EA - A SO - Klin Lab Diagn 1994;(4):25-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 95025167 AU - Ragnaud JM AU - Morlat P AU - Buisson M AU - Longy-Boursier M AU - Monlun E AU - Wone C AU - Lebras M AU - Beylot J AU - Aubertin J TI - [Epidemiological, clinical, biological and developmental aspects of leptospirosis: apropos of 30 cases in Aquitaine] LA - Fre MH - Adolescence MH - Adult MH - Aged MH - English Abstract MH - Female MH - France/epidemiology MH - Human MH - Leptospirosis/complications/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Prognosis MH - Retrospective Studies MH - Time Factors PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 941024 DP - 1994 IS - 0248-8663 TA - Rev Med Interne PG - 452-9 SB - M CY - FRANCE IP - 7 VI - 15 JC - SGJ AA - Author EM - 9501 AB - We have studied retrospectively 30 cases of leptospirosis observed in Aquitaine (South West France) from 1980 till 1992. This review was made in three internal and a nephrology department in Bordeaux hospital. Most cases occurred by indirect contact with infected animals or by occupational exposures. Onset was brutal with fever often associated with painful syndrome and sometimes conjunctival suffusion. Jaundice (70%), acute renal failure (67%), meningitis (50%) and hemorrhagic signs (50%) were among the major visceral manifestations. Diagnosis was always confirmed by micro-agglutination test. Leptospira ictero- hemorrhage was the predominant serogroup found. The outcome was favorable in 22 patients; reversible complications were seen in six cases (five acute renal failure with hemodialysis myocarditis and pulmonary edema in two hemodialysed patients, polyradiculoneuritis). Two patients died (acute respiratory failure and meningo-encephalitis with diffuse hemorrhagic syndrome). The characteristic of our series is the high frequency of hepatorenal syndrome due to the importance of our nephrologist recruitment. Furthermore our study confirm the vital prognostic characters of the pulmonary, renal, hemorrhagic and neurologic complications. No absolute relationship was found between the clinical and laboratory findings and the serotype of leptospira. Penicillin remains the treatment of choice and should be started as soon as possible the avoid the life threatening visceral complications. AD - Clinique medicale et des maladies infectieuses, hopital Pellegrin, Bordeaux, France. RF - 43 PMID- 7938956 TT - Aspects epidemiologiques, cliniques, biologiques et evolutifs de la leptospirose: a propos de 30 observations recueillies en Aquitaine. EA - A SO - Rev Med Interne 1994;15(7):452-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 95003509 AU - Oliva R AU - Infante JF AU - Gonzalez M AU - Perez V AU - Sifontes S AU - Marrero O AU - Valdes Y AU - Farinas M AU - Estevez L AU - Gonzalez I TI - Pathologic-clinical characterization of leptospirosis in a golden Syrian hamster model. LA - Eng MH - Animal MH - *Disease Models, Animal MH - Hamsters MH - Leptospirosis/*pathology MH - Male MH - Mesocricetus/*microbiology PT - JOURNAL ARTICLE DA - 941121 DP - 1994 Summer IS - 0188-0128 TA - Arch Med Res PG - 165-70 CY - MEXICO IP - 2 VI - 25 JC - BIC AA - Author EM - 9501 AB - Experimental leptospirosis was reproduced in golden Syrian hamsters (Mesocricetus aureatus). Evaluation of three Leptospira serogroups (canicola, icterohaemorrhagiae and pomona) was carried out regarding their virulence, production of symptoms and lethal activity. Macroscopic and microscopic studies of tissue lesions were also made. Animals were inoculated with 3.75 x 10(6) to 6 x 10(7) bacteria through the intraperitoneal (IP) route. The clinical development of the disease in Syrian hamsters was characterized by the presence of general symptoms between the third and fifth day after inoculation. With highly virulent strains, the distinctive clinical picture occurred and death followed before the seventh day. The strain of the pomona serogroup proved to be more virulent than those of the other serogroups and produced the most florid picture of the disease. Pathogenic aspects of this process were also studied. AD - Finlay Institute, Havana, Cuba. PMID- 7919806 SO - Arch Med Res 1994 Summer;25(2):165-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 95159228 AU - Smikle MF AU - Morgan OS AU - Barton EN AU - Bailey V AU - Blattner WA TI - Serological tests for Lyme disease in patients with tropical spastic paraparesis and healthy Jamaicans. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Antibodies, Bacterial/isolation & purification MH - Blotting, Western MH - Cross Reactions MH - False Positive Reactions MH - Female MH - Fluorescent Antibody Technique MH - Human MH - Immunoenzyme Techniques MH - Jamaica MH - Lyme Disease/complications/*diagnosis MH - Male MH - Middle Age MH - Paraparesis, Tropical Spastic/blood/*complications RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950314 DP - 1994 IS - 0041-3232 TA - Trop Geogr Med PG - 329-30 SB - M CY - NETHERLANDS IP - 5 VI - 46 JC - WGJ AA - Author EM - 9505 AB - The significance of reactive serological tests for Lyme disease in patients with tropical spastic paraparesis (TSP) was assessed by examining serum samples from 128 of these patients and 200 healthy Jamaicans by Lyme indirect immunofluorescent antibody (IFA), enzyme immuno-assay (EIA) and Western blot analyses. Sera were also examined in serological tests for syphilis (STS), an unabsorbed fluorescent treponemal antibody test and leptospira microagglutination test. The prevalence of positive Lyme IFA and EIA results did not differ significantly between sera from TSP patients (12.5%) and healthy controls (10.0%). Western blot analyses showed that the positive Lyme IFA and EIA results observed in this study were due to false positive reactions. Seventy-five per cent of Lyme IFA/EIS positive sera from TSP patients had treponemal antibodies. Eighty per cent of those from healthy controls were negative in standard STS but 85% were positive when tested in an unabsorbed fluorescent treponemal antibody (FTA). These data indicate that reactive serological tests for Lyme disease in Jamaican TSP patients and healthy Jamaicans are false positive reactions due to cross-reactivity with other spirochaetes, notably Treponema pallidum and non pathogenic treponemes. AD - Department of Microbiology, University of the West Indies, Mona, Kingston, Jamaica. PMID- 7855925 SO - Trop Geogr Med 1994;46(5):329-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 95132879 AU - Courtin JP AU - Carre P AU - Poubeau P AU - Di Francia M AU - Jarlet E AU - Michault A AU - Amat C AU - Arvin-Berod CA TI - [Diffuse alveolar hemorrhage and myositis in icterohemorrhagic leptospirosis. Rapid control by a single bolus of corticoids] LA - Fre MH - Adrenal Cortex Hormones/*administration & dosage MH - Adult MH - Antibiotics/therapeutic use MH - Case Report MH - English Abstract MH - Hemoptysis/etiology MH - Hemorrhage/drug therapy/*etiology/radiography MH - Human MH - Lung Diseases/drug therapy/*etiology/radiography MH - Male MH - Methylprednisolone/administration & dosage MH - Myositis/drug therapy/*etiology MH - *Pulmonary Alveoli/radiography MH - Time Factors MH - Weil's Disease/*complications/drug therapy RN - 0 (Adrenal Cortex Hormones) RN - 0 (Antibiotics) RN - 83-43-2 (Methylprednisolone) PT - JOURNAL ARTICLE DA - 950223 DP - 1994 IS - 0761-8425 TA - Rev Mal Respir PG - 601-3 SB - M CY - FRANCE IP - 6 VI - 11 JC - RZ9 AA - Author EM - 9504 AB - Leptospirosis is one of the commonest causes of diffuse alveolar haemorrhage. Despite good sensitivity to penicillin and current techniques of ventilation, there remains a considerable mortality which is particularly linked to the initial pulmonary disease at presentation. The authors describe a new case of a gravely ill patient with leptospirosis and sever hypoxaemia. There was diffuse alveolar haemorrhage and myositis thus a bolus of corticosteroids was used over the first 24 hours complementary to the traditional treatment. AD - Service de Pneumologie et Maladies Infectieuses, CHG de Saint-Pierre. PMID- 7831513 TT - Hemorragie alveolaire diffuse et myosite au cours d'une leptospirose ictero-hemorragique. Controle rapide par un seul bolus de corticoides. EA - A SO - Rev Mal Respir 1994;11(6):601-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 95128198 AU - Perret JL AU - Moussavou-Kombila JB AU - Duong TH AU - Berthonneau JP AU - Nguemby-Mbina C TI - [First clinical and serological description of leptospirosis in Gabon] LA - Fre MH - Adult MH - Bilirubin/blood MH - Case Report MH - English Abstract MH - Gabon MH - Human MH - Leptospirosis/*diagnosis/ultrasonography MH - Leukocyte Count MH - Male RN - 635-65-4 (Bilirubin) PT - JOURNAL ARTICLE DA - 950217 DP - 1994 TA - Bull Soc Pathol Exot PG - 181-2 SB - M CY - FRANCE IP - 3 VI - 87 JC - BK9 AA - Author EM - 9504 AB - We report the first case of leptospirosis describe in Gabon. Several environmental factors could favour the transmission of the disease in that country. AD - Service de Medecine "A", Centre Hospitalier de Libreville, Gabon. PMID- 7827519 TT - Premiere description clinique et serologique de la leptospirose au Gabon. EA - A SO - Bull Soc Pathol Exot 1994;87(3):181-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 95098376 AU - Wiecek A AU - Zeier M AU - Ritz E TI - Role of infection in the genesis of acute renal failure. LA - Eng MH - Animal MH - Bacterial Infections/complications MH - Cytokines/physiology MH - Endotoxins/toxicity MH - History of Medicine, 19th Cent. MH - History of Medicine, 20th Cent. MH - Human MH - Infection/*complications MH - Kidney Failure, Acute/epidemiology/*etiology/history RN - 0 (Cytokines) RN - 0 (Endotoxins) PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 950126 DP - 1994 IS - 0931-0509 TA - Nephrol Dial Transplant PG - 40-4 SB - M CY - ENGLAND VI - 9 Suppl 4 JC - N7J AA - Author EM - 9503 AB - While most experimental models of acute renal failure (ARF) involve ischaemic or toxic damage to the kidney in non-infected animals, a surprisingly large proportion of patients with ARF exhibit signs of septicaemia or systemic reaction to local infections. This clinical observation suggests an important role of infection-related mediator mechanisms in the genesis of ARF. Another important aspect is the occurrence of ARF in the context of infections with nephrotropic viruses (e.g. hantavirus accounting for approximately 5% of non- surgical ARF in Germany) and nephrotropic bacteria (e.g. leptospirosis). AD - Department of Internal Medicine, Ruperto Carola University, Heidelberg, Germany. RF - 66 PMID- 7800267 SO - Nephrol Dial Transplant 1994;9 Suppl 4:40-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 95311805 AU - Bacic M AU - Seguljev Z AU - Vukovic B AU - Adamov R AU - Vidic B TI - [Zoonoses in Vojvodina. III. Results of a seroepidemiologic study of leptospirosis in Vojvodina] LA - Scr MH - Adolescence MH - Adult MH - Antibodies, Bacterial/blood MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology MH - Male MH - Occupational Diseases/epidemiology MH - Seroepidemiologic Methods MH - Yugoslavia/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 950727 DP - 1994 IS - 0025-8105 TA - Med Pregl PG - 243-6 CY - YUGOSLAVIA IP - 7-8 VI - 47 JC - M8U AA - Author EM - 9509 AB - 2697 persons professionally exposed to leptospira working in contaminated waters and grounds or due to contact with infected animals or their products were seroepidemiologically examined. It was established that the presence of leptospirosis in certain categories of examined persons is three to more than ten times higher in relation with it's presence in the control groups. The most frequent serotype was Leptospira pomona. None of the seropositive persons gave data about having leptospirous infection which might be the consequence of asymptomatic infection or unidentified and not registering of the clinically manifested diseases. AD - Zavod za zastitu zdravlja, Zrenjanin. PMID- 7791675 TT - Zooantroponoze u Vojvodini. III. Rezultati seroepidemioloskog ispitivanja leptospiroza u Vojvodini. EA - A SO - Med Pregl 1994;47(7-8):243-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 95257851 AU - Seguljev Z AU - Vukovic B AU - Bacic M AU - Stefanovic S AU - Petrovic M AU - Brcan N TI - [Zoonoses in Vojvodina. II. Epidemiologic characteristics of leptospirosis in Vojvodina] LA - Scr MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology/transmission MH - Male MH - Middle Age MH - Yugoslavia/epidemiology PT - JOURNAL ARTICLE DA - 950607 DP - 1994 IS - 0025-8105 TA - Med Pregl PG - 164-7 CY - YUGOSLAVIA IP - 5-6 VI - 47 JC - M8U AA - Author EM - 9508 AB - On the basis of reported cases of sickness--death due to leptospirosis and the epidemiologic investigation of 38 sick individuals, epidemiologic characteristics of anthropozoonosis in Vojvodina were analyzed. It has been established that this disease is registered in the form of individual cases, mostly in persons belonging to the productive population. Infection usually happens during the summer months and due to contact with contaminated water. High lethality and antibodies of leptospirosis icterohaemorrhagiae in 55.3% of samples of the serum of the sick point to the fact that only clinically severe forms of the disease were registered. AD - Odeljenje za epidemiologiju, Pokrajinski zavod za zdravstvenu zastitu, Novi Sad. PMID- 7739456 TT - Zooantroponoze u Vojvodini. II. Epidemioloske karakteristike leptospiroza u Vojvodini. EA - A SO - Med Pregl 1994;47(5-6):164-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 94067283 AU - Bohlmann BJ TI - Clinical problem-solving: leptospirosis [letter; comment] LA - Eng MH - Adult MH - Animal MH - Animals, Domestic MH - Case Report MH - Diagnosis, Differential MH - Feces/microbiology MH - Female MH - Human MH - Leptospirosis/*diagnosis MH - Lyme Disease/diagnosis MH - Mice MH - Urine/microbiology PT - COMMENT PT - LETTER DA - 940106 DP - 1993 Dec 30 IS - 0028-4793 TA - N Engl J Med PG - 2041 SB - A SB - M SB - X CY - UNITED STATES IP - 27 VI - 329 JC - NOW EM - 9403 CM - Comment on: N Engl J Med 1993 Aug 5;329(6):413-6 RO - M:LC2 PMID- 8247093 LR - 940323 SO - N Engl J Med 1993 Dec 30;329(27):2041 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 94067282 AU - Gordon ME TI - Clinical problem-solving: leptospirosis [letter; comment] LA - Eng MH - Case Report MH - Diagnosis, Differential MH - Human MH - Leptospirosis/*diagnosis MH - Medical History Taking MH - Water Microbiology PT - COMMENT PT - LETTER DA - 940106 DP - 1993 Dec 30 IS - 0028-4793 TA - N Engl J Med PG - 2040-1 SB - A SB - M SB - X CY - UNITED STATES IP - 27 VI - 329 JC - NOW EM - 9403 CM - Comment on: N Engl J Med 1993 Aug 5;329(6):413-6 RO - M:LC2 PMID- 8247092 LR - 940323 SO - N Engl J Med 1993 Dec 30;329(27):2040-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 94117292 AU - Anderson JF AU - Miller DA AU - Post JE AU - Johnson RC AU - Magnarelli LA AU - Andreadis TG TI - Isolation of Leptospira interrogans serovar grippotyphosa from the skin of a dog. LA - Eng MH - Animal MH - Case Report MH - Dog Diseases/*microbiology MH - Dogs MH - Hamsters MH - Leptospira interrogans/classification/*isolation & purification/pathogenicity MH - Leptospirosis/microbiology/*veterinary MH - Male MH - Mesocricetus MH - Skin/*microbiology MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE ID - AI-30548/AI/NIAID DA - 940222 DP - 1993 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1550-1 SB - M CY - UNITED STATES IP - 11 VI - 203 JC - HAV AA - Author EM - 9404 AB - Leptospira interrogans serovar grippotyphosa was isolated from the skin of a 14-year-old male dog with deteriorating health. Necropsy revealed numerous lesions characteristic of aged dogs, but no evidence of acute hepatitis or nephritis, which are common features of pathogenic Leptospira infections. Antibody to Leptospira was not detected in the dog's serum by microagglutination. Leptospires grew slowly in Barbour- Stoenner-Kelly medium, a medium commonly used to isolate Borrelia, but then grew abundantly in Tween 80-bovine albumin leptospire medium. The isolate was pathogenic to a hamster and was identified by microagglutination and restriction endonuclease analysis. AD - Department of Entomology, Connecticut Agricultural Experiment Station, New Haven 06504. PMID- 8288477 SO - J Am Vet Med Assoc 1993 Dec 1;203(11):1550-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [88 medline neighbors] UI - 94219246 AU - Valente C AU - Faria MJ AU - Trindade L AU - Barros MS AU - Vieira AA AU - Albuquerque I AU - Rodrigues R TI - [Serologic diagnosis of several infectious diseases] LA - Por MH - Boutonneuse Fever/diagnosis MH - Brucellosis/diagnosis MH - Communicable Diseases/*diagnosis MH - Cytomegalovirus Infections/diagnosis MH - English Abstract MH - Hepatitis, Viral, Human/diagnosis MH - Herpes Simplex/diagnosis MH - Herpesviridae Infections/diagnosis MH - Herpesvirus 4, Human MH - Human MH - HIV Infections/diagnosis MH - Leptospirosis/diagnosis MH - Rubella/diagnosis MH - Serodiagnosis/methods MH - Syphilis Serodiagnosis MH - Toxoplasmosis/diagnosis MH - Tumor Virus Infections/diagnosis MH - Typhoid/diagnosis PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 940523 DP - 1993 Dec IS - 0253-0562 TA - Acta Med Port PG - 605-12 CY - PORTUGAL IP - 12 VI - 6 JC - 13V AA - Author EM - 9407 AB - Serological tests are, in some situations, the only method of diagnosis of some infectious diseases. The authors make a review of the literature about the most important tests used in the most common infectious diseases and also their interpretation. It is important to point out that serology should not be considered alone but compared to clinical manifestations presented by the patient. It is also necessary, in some cases, to obtain two samples of serum, to confirm if there is an increase in the antibodies' titles. The results sent from the laboratory should be interpreted based on references given by it. AD - Servico de Infecciologia, Patologia Clinica, Hematologia, Centro Hospitalar de Coimbra. RF - 71 PMID- 8165932 TT - Diagnostico serologico de algumas doencas infecciosas. EA - A SO - Acta Med Port 1993 Dec;6(12):605-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 94211551 AU - Herrmann JL TI - Genomic techniques for identification of Leptospira strains. LA - Eng MH - DNA, Bacterial/genetics MH - Electrophoresis, Gel, Pulsed-Field MH - Hybridization MH - In Vitro MH - Leptospira/*classification/genetics MH - Leptospira interrogans/*classification/genetics MH - Nucleic Acid Hybridization MH - Polymerase Chain Reaction MH - Restriction Mapping MH - RNA, Ribosomal/genetics RN - 0 (DNA, Bacterial) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 940516 DP - 1993 Dec IS - 0369-8114 TA - Pathol Biol (Paris) PG - 943-50 SB - M CY - FRANCE IP - 10 VI - 41 JC - OSG AA - Author EM - 9407 AB - Within the Leptospiraceae family, the genus Leptospira is divided into the pathogenic L. interrogans sensu lato and the saprophytic L. biflexa sensu lato. Based on DNA-DNA hybridization, L. interrogans sensu lato has been shown to contain 7 different genomic species. Each genomic species contains numerous serovars. Pulsed-field genetic studies performed during this work demonstrated a great heterogeneity of serovars, within genomic species, based on restriction length polymorphism analysis. In contrast, an identified serovar, despite the time and region of isolation, has been shown to be highly stable in its genomic structure. The most likely reasons for this finding include the long generation time of these bacteria and the lack of acquisition of heterologous DNA. New identification techniques, based on gene amplification, have been used for Leptospira strains. These techniques represent the first available to facilitate the study of the epidemiology of Leptospira. AD - Unite de Bacteriologie Moleculaire et Medicale, Institut Pasteur, Paris, France. RF - 58 RO - M:CNR PMID- 8159475 LR - 940525 SO - Pathol Biol (Paris) 1993 Dec;41(10):943-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 94200756 AU - Wu W AU - Dai B TI - [PCR amplification of the leptospiral DNAs from different genus and species with the variable sequences of 16S rRNA gene] LA - Chi MH - Base Sequence MH - DNA Primers MH - DNA, Bacterial/analysis/*genetics MH - English Abstract MH - Leptospira interrogans/classification/*genetics MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - RNA, Ribosomal, 16S/*genetics MH - Sequence Homology MH - Support, Non-U.S. Gov't RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 940510 DP - 1993 Dec IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 359-63 CY - CHINA IP - 4 VI - 24 JC - GEB AA - Author EM - 9407 AB - We designed a pair of primers from the variable regions (V2 and V4) of 16S rRNA gene of Leptospira interrogans, i. e. PI: 5'GGG AAC CTA ATA CTG GAT GG; PII: 5' ACA TAG TTT CAA GTG GAG GC, and amplified the leptospiral DNAs from different genus and species. When denaturing with 55 degrees C, all DNAs of L. interrogans had the same products not only in length but also with Kpn I-digested pattern. The DNA of L. biflexa could be amplified with a c. a. 280 bp-band but not digested by Kpn I, while the DNAs of Leptonema and other control bacteria had no amplification. In addition, the products of L. interrogans spp. could be hybridized with the PCR product of L. interrogans serovar lai strain Lai labelled with 32P, while the product of L. biflexa had no hybridization. It proved that the 16S rRNA gene primers is useful for the classification and detection of leptospires. PMID- 8150433 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1993 Dec;24(4):359-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 94197584 AU - Bezerra HM AU - Ataide Junior L AU - Hinrichsen SL AU - Travassos FM AU - Travassos PT AU - Silva MJ AU - Silva MB TI - [Involvement of the nervous system in leptospirosis. III. Immunologic reactions in the blood and cerebrospinal fluid] LA - Por MH - Adolescence MH - Adult MH - Aged MH - Agglutination Tests MH - Antigens, Bacterial/analysis/cerebrospinal fluid MH - Central Nervous System Diseases/cerebrospinal fluid/*diagnosis MH - Diagnosis, Differential MH - English Abstract MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/cerebrospinal fluid/*diagnosis MH - Male MH - Middle Age RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 940505 DP - 1993 Dec IS - 0004-282X TA - Arq Neuropsiquiatr PG - 469-74 SB - M CY - BRAZIL IP - 4 VI - 51 JC - 8WY AA - Author EM - 9407 AB - From January 1st up to September 30th 1990, 77 patients with leptospirosis were admitted at the Infectious and Parasitic Diseases Service of the Hospital das Clinicas of the Universidade Federal de Pernambuco. The majority (64) were male patients, and average age was 28 years old. Serovars icterohaemorrhagic and canicola were the most frequent. CSF examination was performed in 67 (87.0%) patients and it was abnormal in 64 (95.52%). Micro-agglutination test for leptospirosis with live antigens was performed in CSF, as well as immunological tests for syphilis, cysticercosis and schistosomiasis for differential diagnosis. Concerning the serovar identification, results of microagglutination test for leptospirosis in CSF were significant considering the similitude of responses when compared to those found for blood samples. AD - Servico de Doencas Infecciosas e Parasitarias do Hospital, Clinicas da Universidade Federal de Pernambuco (SDIP/UFPE), Brasil. PMID- 8147747 TT - Comprometimento do sistema nervoso na leptospirose. III. Reacoes imunologicas no sangue e liquido cefalorraqueano. EA - A SO - Arq Neuropsiquiatr 1993 Dec;51(4):469-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 94197583 AU - Bezerra HM AU - Ataide Junior L AU - Hinrichsen SL AU - Travassos FM AU - Travassos PT AU - Silva MJ AU - Silva MB TI - [Involvement of the nervous system in leptospirosis. II. Cerebrospinal fluid evaluation] LA - Por MH - Central Nervous System Diseases/*cerebrospinal fluid MH - English Abstract MH - Human MH - Leptospirosis/*cerebrospinal fluid PT - JOURNAL ARTICLE DA - 940505 DP - 1993 Dec IS - 0004-282X TA - Arq Neuropsiquiatr PG - 464-8 SB - M CY - BRAZIL IP - 4 VI - 51 JC - 8WY AA - Author EM - 9407 AB - From January 1st up to September 30th 1990, 77 patients with leptospirosis diagnosis confirmed by laboratory studies were admitted at the Infectious and Parasitic Disease Service of the Hospital das Clinicas of the Universidade Federal de Pernambuco. The neurological exam was abnormal in 70 of the patients (90.91%). The cerebrospinal fluid (CSF) examination was carried out on 67 (87%) of the patients; it was abnormal in 64 (95.52%) yielding hypercytosis in the majority of cases. There was no difference in the CSF behavior in report to the several neurological forms nor in relation to the icteric or non- icteric forms of the disease. Significant were the results for the microscopic agglutination tests for leptospirosis in the CSF. AD - Servico de Doencas Infecciosas e Parasitarias do Hospital, Clinicas da Universidade Federal de Pernambuco SDIP/UFPE. PMID- 8147746 TT - Comprometimento do sistema nervoso na leptospirose. II. Avaliacao do liquido cefalorraqueano. EA - A SO - Arq Neuropsiquiatr 1993 Dec;51(4):464-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [93 medline neighbors] UI - 94197582 AU - Bezerra HM AU - Ataide Junior L AU - Hinrichsen SL AU - Travassos FM AU - Travassos PT AU - Silva MJ AU - Silva MB TI - [Involvement of the nervous system in leptospirosis. I. Evaluation of neurologic aspects] LA - Por MH - Central Nervous System Diseases/diagnosis/*etiology MH - English Abstract MH - Human MH - Leptospirosis/*complications MH - Neurologic Examination PT - JOURNAL ARTICLE DA - 940505 DP - 1993 Dec IS - 0004-282X TA - Arq Neuropsiquiatr PG - 457-63 SB - M CY - BRAZIL IP - 4 VI - 51 JC - 8WY AA - Author EM - 9407 AB - From January 1st up to September 30th 1990, 77 patients with leptospirosis confirmed by laboratory studies were admitted at the Infectious and Parasitic Diseases Service of the Hospital das Clinicas of the Universidade Federal de Pernambuco. Clinical manifestations had sudden onset with presence of fever, headache, chills and muscle pains. Plurisystemic involvement was observed both in the icteric and in the non-icteric patients. The neurological exam was abnormal in 70 of the patients (90.91%). Neurological findings were essentially variable. Though in a transitory form, they allowed the observation of the following clinical forms: meningoencephalitis and polyneuritis in association, meningoencephalitis, polyneuritis, and subarachnoid hemorrhage. AD - Servico de Doencas Infecciosas e Parasitarias do Hospital, Universidade Federal de Pernambuco (SDIP/UFPE), Brasil. PMID- 8147745 TT - Comprometimento do sistema nervoso na leptospirose: I. Avaliacao dos aspectos neurologicos. EA - A SO - Arq Neuropsiquiatr 1993 Dec;51(4):457-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 94183977 AU - Sharma OP AU - Maheshwari A TI - Lung diseases in the tropics. Part 2: Common tropical lung diseases: diagnosis and management. LA - Eng MH - Amebiasis/diagnosis/drug therapy MH - AIDS-Related Opportunistic Infections/complications MH - Human MH - Leptospirosis/diagnosis MH - Lung Diseases/*diagnosis/drug therapy/*microbiology MH - Malaria/diagnosis/drug therapy MH - Melioidosis/diagnosis MH - Typhoid/diagnosis PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, ACADEMIC DA - 940425 DP - 1993 Dec IS - 0962-8479 TA - Tuber Lung Dis PG - 359-70 SB - M CY - SCOTLAND IP - 6 VI - 74 JC - A8C AA - Author EM - 9406 AB - This is the second of the two articles discussing clinical features, radiographic abnormalities, laboratory tests, pathogenesis and therapy of common tropical disorders affecting the lungs. We have arbitrarily selected the diseases, which are worldwide in distribution and demand urgency in addressing the problems of morbidity and mortality. The tropical physician is often reduced to administering pills, capsules or liquids. Our aim is to provide succinct and clear descriptions combining scientific information with common sense clinical wisdom. AD - Division of Pulmonary and Critical Care Medicine, USC School of Medicine, Los Angeles 90033. RF - 60 PMID- 8136488 SO - Tuber Lung Dis 1993 Dec;74(6):359-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 94174904 AU - Broll S AU - Waldvogel AS AU - Rosskopf M AU - Corboz L AU - Pospischil A TI - [The infectious causes of abortion and stillbirth in swine in Switzerland] LA - Ger MH - Abortion, Veterinary/*microbiology MH - Animal MH - Bacterial Infections/microbiology/*veterinary MH - English Abstract MH - Female MH - Fetal Death/microbiology/*veterinary MH - Fetal Diseases/microbiology/veterinary MH - Parvoviridae Infections/microbiology/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*microbiology MH - Switzerland PT - JOURNAL ARTICLE DA - 940412 DP - 1993 Dec IS - 0931-1793 TA - Zentralbl Veterinarmed [B] PG - 641-53 CY - GERMANY IP - 9-10 VI - 40 JC - Y72 AA - Author EM - 9406 AB - Fetuses and placentae of 171 cases of porcine abortion, stillbirth and mummification were examined for pathological lesions, bacterial infections and PPV (porcine parvovirus) infection. Furthermore IgG (immunoglobulin G) levels were determined in fetal body fluids. Selected maternal sera were tested for antibodies against Leptospira, Aujeszky's disease and hog cholera. PPV infection was diagnosed in 29.2% of all cases. Bacterial abortion was diagnosed in 8.2%. Indications for an infectious agent were demonstrated in about 10% of the cases. The etiology of the abortion could not be identified in 52%. Inflammatory alterations in association with the isolation of bacteria consisted of neutrophilic infiltration and necrosis and were of particular value to differentiate bacterial contamination from infection. Infiltrations of mononuclear leucocytes in brain, leptomeninx, kidney or myocard were observed in about 50% of the fetuses with PPV infection. IgG levels were consistently elevated in fetuses serologically positive for PPV, but also in two fetuses, where no infectious agent could be identified. AD - Institut fur Veterinarpathologie, Universitat Zurich. PMID- 8128797 TT - Untersuchungen zu infektiosen Ursachen fur Aborte und Totgeburten beim Schwein in der Schweiz. EA - A SO - Zentralbl Veterinarmed [B] 1993 Dec;40(9-10):641-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 94174686 AU - Gerritsen MJ AU - Koopmans MJ AU - Olyhoek T TI - Effect of streptomycin treatment on the shedding of and the serologic responses to Leptospira interrogans serovar hardjo subtype hardjobovis in experimentally infected cows. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/blood MH - Bacteriuria/drug therapy/microbiology/*veterinary MH - Carrier State/drug therapy/immunology/microbiology/*veterinary MH - Cattle MH - Cattle Diseases/*drug therapy/immunology/microbiology MH - DNA, Bacterial/analysis MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Female MH - Leptospira interrogans/genetics/immunology/isolation & purification MH - Leptospirosis/drug therapy/immunology/microbiology/*veterinary MH - Polymerase Chain Reaction/veterinary MH - Streptomycin/pharmacology/*therapeutic use MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (DNA, Bacterial) RN - 57-92-1 (Streptomycin) PT - JOURNAL ARTICLE DA - 940412 DP - 1993 Dec IS - 0378-1135 TA - Vet Microbiol PG - 129-35 SB - M CY - NETHERLANDS IP - 1-2 VI - 38 JC - XBW AA - Author EM - 9406 AB - Shedding patterns of and serologic responses to Leptospira interrogans serovar hardjo subtype hardjobovis (L. hardjobovis) have been studied in experimentally infected cows treated with streptomycin in comparison to experimentally infected cows receiving no such treatment. Fourteen cows were experimentally infected with L. hardjobovis, and blood and urine samples were collected weekly for 24 weeks. The microscopic agglutination test (MAT) and enzyme-linked immunosorbent assay (ELISA) were used to determine serologic responses. The polymerase chain reaction (PCR) was used to determine bacterial shedding in urine. Six weeks after infection six cows were treated with the antibiotic streptomycin (25 mg/kg body weight/day); three cows were treated only once, and the remaining three were treated for five consecutive days. After treatment all six cows had lower serologic responses compared to the untreated cows. The treated cows became also PCR-negative two days after the first treatment, whereas the eight untreated cows remained PCR-positive for at least 70 days. Cows that stopped shedding did not resume shedding within the observation period. Since streptomycin treatment reduces the period of shedding, transmission of leptospira via contaminated urine might be prevented by a single treatment of an infected herd. AD - Department of Bacteriology, Central Veterinary Institute, Lelystad, Netherlands. PMID- 8128596 SO - Vet Microbiol 1993 Dec;38(1-2):129-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 94172290 AU - Cinco M AU - Perticarari S AU - Presani G AU - Dobrina A AU - Liut F TI - Biological activity of a peptidoglycan extracted from Leptospira interrogans: in vitro studies. LA - Eng MH - Cell Division/drug effects MH - Complement Activation/drug effects MH - Human MH - In Vitro MH - Leptospira interrogans/immunology/*physiology MH - Leptospirosis/etiology MH - Leukocytes, Mononuclear/cytology/drug effects MH - Mitogens/pharmacology MH - Monocytes/drug effects/physiology MH - Neutrophils/drug effects/physiology MH - Peptidoglycan/immunology/isolation & purification/*pharmacology MH - Phagocytosis/drug effects MH - Respiratory Burst/drug effects RN - 0 (Mitogens) RN - 0 (Peptidoglycan) PT - JOURNAL ARTICLE DA - 940412 DP - 1993 Dec IS - 0022-1287 TA - J Gen Microbiol PG - 2959-64 SB - M CY - ENGLAND VI - 139 ( Pt 12) JC - I87 AA - Author EM - 9406 AB - Peptidoglycan (PG) has been isolated from some species of spirochaetes, including Leptospira interrogans. Although leptospiral PG has been chemically characterized, no study has been carried out on its potential biological activity. Since PG of Treponema and Borrelia is biologically active both in vivo and in vitro, we investigated the capacity of a leptospiral PG preparation to induce relevant biological effects. PG extracted from L. interrogans strain Teramo was mitogenic at 0.1 microgram ml-1 for human peripheral blood mononuclear cells (PBMC) since it increased the PBMC fraction positive for Ki-67, an antigen expressed by human proliferating cells; at 4 micrograms ml-1, PG was able to induce complement consumption and to stimulate leucocyte phagocytosis and the metabolic burst of resting as well as phagocytosing leucocytes. These findings indicate that Leptospira PG may play a role in modulating the immunocompetent cell functions and suggest that PG can contribute to the host response during Leptospira infection. AD - Istituto di Microbiologia, Universita di Trieste, Italy. PMID- 8126423 SO - J Gen Microbiol 1993 Dec;139 ( Pt 12):2959-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 94098581 AU - Elbers AR AU - van Rossem H AU - Schukken YH AU - Martin SW AU - van Exsel AC AU - Friendship RM AU - Tielen MJ TI - [Return to estrus following first insemination in sow herds (incidence and association with reproductivity and various blood parameters)] LA - Dut MH - Animal MH - English Abstract MH - *Estrus MH - Female MH - Gamma-Globulins/analysis MH - Insemination, Artificial/*veterinary MH - Progesterone/blood MH - Reproduction MH - Serum Albumin/analysis MH - Swine/blood/*physiology RN - 0 (Gamma-Globulins) RN - 0 (Serum Albumin) RN - 57-83-0 (Progesterone) PT - JOURNAL ARTICLE DA - 940203 DP - 1993 Dec 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 769-77 SB - M CY - NETHERLANDS IP - 23 VI - 118 JC - VRY AA - Author EM - 9404 AB - As no systematic study has been done to get an accurate estimate of the incidence of return to oestrus after first insemination in sows in the Netherlands, the objectives of this investigation were: 1) to obtain an estimate of the incidence of return to oestrus after insemination at the herd level; 2) to investigate the association between incidence of return to oestrus after first insemination and reproduction characteristics to get an impression of the economic importance. These objectives were investigated using the reproduction results of 240 swine breeding herds in The Southern Netherlands in 1987, using their CBK plus computerized herd management records. The average incidence of return to oestrus after first insemination on a herd level was 16.9 per 100 first inseminations. An increase of incidence with 10 returns per 100 first inseminations, corrected for confounders in a multiple linear regression model, was associated with a decrease of approximately 0.3 liveborn piglets/sow/year. Thereupon individual sows were followed in 1988 and 1989 prospectively in 37 sow herds from weaning to insemination, returning to oestrus or not after first insemination to farrowing. The investigation focused in particular on the relationship between returning to oestrus after first insemination and incident infection with porcine parvovirus (PPV) and Leptospira interrogans serovar bratislava (L. bratislava). During a number of consecutive farm visits sows were blood sampled at weaning and again a blood sample was taken 6 weeks later. The final dataset that was analysed consisted of 161 animals that did not return to oestrus after first insemination and 158 animals that returned to oestrus after first insemination.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Gezondheidsdienst voor Dieren in Zuid-Nederland, Boxtel. PMID- 7505958 CU - 95 TT - Terugkomen na eerste inseminatie op zeugenbedrijven (incidentie en associatie met reproduktiviteit en een aantal bloedparameters). EA - A SO - Tijdschr Diergeneeskd 1993 Dec 1;118(23):769-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 94141247 AU - Alani FS AU - Mahoney MP AU - Ormerod LP AU - Wright PA AU - Garrues M TI - Leptospirosis presenting as atypical pneumonia, respiratory failure and pyogenic meningitis. LA - Eng MH - Adult MH - Antibiotics/therapeutic use MH - Case Report MH - Human MH - *Leptospira interrogans MH - Leptospirosis/*diagnosis/drug therapy MH - Male MH - Meningitis, Bacterial/*diagnosis/drug therapy MH - Pneumonia/*diagnosis/drug therapy MH - Respiratory Insufficiency/*diagnosis/drug therapy RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 940317 DP - 1993 Nov IS - 0163-4453 TA - J Infect PG - 281-3 SB - M CY - ENGLAND IP - 3 VI - 27 JC - IG9 AA - Author EM - 9405 AB - A 20-year-old man who looked after a pack of hounds was admitted with a short history of headache, fever, haemoptysis and muscle cramps. Investigations showed type I respiratory failure with diffuse pneumonitis, pyogenic meningitis and raised liver enzymes. Leptospirosis was suspected and treated with the appropriate antibiotics leading to a full recovery. The diagnosis was confirmed by a titre of I/2560 to Leptospira icterohaemorrhagiae. The case illustrates an unusual presentation of this infection and argues for early antibiotic treatment. AD - Department of Medicine, Blackburn Royal Infirmary, Lancashire, U.K. PMID- 8308321 SO - J Infect 1993 Nov;27(3):281-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 94129639 AU - Kocianova E AU - Kozuch O AU - Bakoss P AU - Rehacek J AU - Kovacova E TI - The prevalence of small terrestrial mammals infected with tick-borne encephalitis virus and leptospirae in the foothills of the southern Bavarian forest, Germany. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Antibodies, Viral/blood MH - Arachnid Vectors MH - *Disease Reservoirs MH - Encephalitis Viruses, Tick-Borne/immunology MH - Encephalitis, Tick-Borne/epidemiology/transmission/*veterinary MH - Fleas MH - Germany/epidemiology MH - Insect Vectors MH - Leptospiraceae/immunology MH - Leptospirosis/epidemiology/transmission/*veterinary MH - Mammals/*microbiology/parasitology MH - Mite Infestations/epidemiology MH - Mites MH - Muridae/microbiology/parasitology MH - Rodent Diseases/epidemiology MH - Shrews/microbiology/parasitology MH - Support, Non-U.S. Gov't MH - Tick Infestations/epidemiology MH - Ticks RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 940310 DP - 1993 Nov IS - 0943-0938 TA - Appl Parasitol PG - 283-90 SB - M CY - GERMANY IP - 4 VI - 34 JC - BSF AA - Author EM - 9405 AB - In the district of Grafenau/Freyung (Bavaria, Germany), 266 specimens of small terrestrial mammals of 8 species were captured using live traps. From these mammals, Apodemus flavicollis (42.1%) and Clethrionomys glareolus (39.5%) were prevalent. All animals were tested for neutralizing antibodies to tick-borne encephalitis (TBE) virus and agglutinating antibodies to leptospirae. Seropositivity against TBE virus was 14.0% and against leptospirae 7.9%, respectively. Seropositivity to leptospirae appeared to be primarily to Leptospira grippotyphosa, less to Australis and occasionally to Javanica serovars. Only one A. flavicollis specimen was positive to both pathogens tested. The parasitocoenosis of trapped micromammals with ectoparasites consisted of 69.5% from ticks (mainly Ixodes ricinus, less from I. trianguliceps), 16.1% of mites (primarily Laelaps agilis) and 14.3% of fleas (mostly Ctenophthalmus agyrtes). AD - Institute of Virology, Slovak Academy of Sciences, Bratislava. PMID- 8298661 SO - Appl Parasitol 1993 Nov;34(4):283-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 94086790 AU - Corney BG AU - Colley J AU - Djordjevic SP AU - Whittington R AU - Graham GC TI - Rapid identification of some Leptospira isolates from cattle by random amplified polymorphic DNA fingerprinting. LA - Eng MH - Animal MH - Cattle/*microbiology MH - *DNA Fingerprinting MH - DNA, Bacterial/*analysis MH - Gene Amplification MH - Leptospira/genetics/*isolation & purification MH - Polymerase Chain Reaction RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940127 DP - 1993 Nov IS - 0095-1137 TA - J Clin Microbiol PG - 2927-32 SB - M CY - UNITED STATES IP - 11 VI - 31 JC - HSH AA - Author EM - 9403 AB - We compared random amplified polymorphic DNA (RAPD) fingerprinting with cross-absorption agglutination and restriction enzyme analysis for typing bovine leptospires. Using RAPD fingerprinting, we examined a number of Leptospira serovars, namely, hardjo genotypes bovis and prajitno, pomona, balcanica, tarassovi, swajizak, kremastos, australis, and zanoni, which are likely to be isolated from Australian cattle. Each serovar and genotype had a unique RAPD profile. Of 26 field isolates of Leptospira, 23 were identified as hardjo genotype bovis subtype A, 2 were identified as zanoni, and 1 was identified as pomona by RAPD fingerprinting, and their types were confirmed by cross- absorption agglutination and restriction enzyme analysis. AD - Animal Research Institute, Queensland Department of Primary Industries, Moorooka, Australia. PMID- 8263177 SO - J Clin Microbiol 1993 Nov;31(11):2927-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 94044943 AU - Merien F AU - Perolat P AU - Mancel E AU - Persan D AU - Baranton G TI - Detection of Leptospira DNA by polymerase chain reaction in aqueous humor of a patient with unilateral uveitis [letter] LA - Eng MH - Adult MH - Aqueous Humor/*microbiology MH - Base Sequence MH - Case Report MH - DNA, Viral/*isolation & purification MH - Human MH - Leptospirosis/complications/*genetics MH - Male MH - Molecular Sequence Data MH - Polymerase Chain Reaction/*methods MH - Support, Non-U.S. Gov't MH - Uveitis/etiology/*microbiology RN - 0 (DNA, Viral) PT - LETTER DA - 931129 DP - 1993 Nov IS - 0022-1899 TA - J Infect Dis PG - 1335-6 SB - A SB - M CY - UNITED STATES IP - 5 VI - 168 JC - IH3 EM - 9402 PMID- 8228381 SO - J Infect Dis 1993 Nov;168(5):1335-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 94360675 AU - Stoianova NA AU - Semenovich VN AU - Sergeiko LM AU - Rusal'chuk VV TI - [Dogs as the possible source of leptospirosis in people] LA - Rus MH - Animal MH - *Disease Vectors MH - Dog Diseases/epidemiology/*transmission MH - *Dogs MH - Female MH - Human MH - *Leptospira canicola MH - Leptospirosis/epidemiology/*transmission/*veterinary MH - Male MH - Russia/epidemiology MH - Seroepidemiologic Methods MH - Urban Population/statistics & numerical data MH - Weil's Disease/epidemiology/transmission/veterinary PT - JOURNAL ARTICLE DA - 940930 DP - 1993 Nov-Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 46-8 SB - M CY - RUSSIA IP - 6 JC - Y9O EM - 9412 PMID- 8079558 TT - Sobaki kak vozmozhnyi istochnik leptospiroza u liudei. SO - Zh Mikrobiol Epidemiol Immunobiol 1993 Nov-Dec;(6):46-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 94103733 AU - Hookey JV AU - Bryden J AU - Gatehouse L TI - The use of 16S rDNA sequence analysis to investigate the phylogeny of Leptospiraceae and related spirochaetes. LA - Eng MH - Base Sequence MH - Comparative Study MH - DNA, Bacterial/*genetics MH - DNA, Ribosomal/*genetics MH - Leptospiraceae/*genetics MH - Molecular Sequence Data MH - *Phylogeny MH - RNA, Bacterial/genetics MH - RNA, Ribosomal, 16S/genetics MH - Spirochaeta/*genetics RN - 0 (DNA, Bacterial) RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 940208 DP - 1993 Nov IS - 0022-1287 TA - J Gen Microbiol PG - 2585-90 SB - M CY - ENGLAND VI - 139 ( Pt 11) JC - I87 AA - Author EM - 9404 AB - The 16S rDNA sequences from 15 Leptospiraceae were determined by automated PCR-directed cycle sequencing. Nucleotide comparisons, including those from published sequences for Leptospira canicola Moulton and Serpulina spp., were used to construct phylogenetic trees. Serpulina hyodysenteriae and S. innocens were related to each other but were distinct from the Leptospiraceae comprising Leptospira parva incertae sedis (Turneria parva H), Leptonema illini and Leptospira spp. The pathogenic and the saprophytic leptospires were distinct and separated from each other. Leptospira inadai occupied an intermediate position between the two forms. The pathogens formed three groups. Group I was represented by L. interrogans sensu stricto and L. kirschneri, Group II by L. weilii, L. borgpetersenii and L. santarosai, and Group III comprised L. noguchii and L. meyeri. The saprophytic species, L. wolbachii and L. biflexa sensu stricto shared about 99% sequence similarity. The freshwater isolates were distinct from the marine isolate L. biflexa sensu lato ancona Ancona Porto. AD - PHLS Leptospira Reference Laboratory, County Hospital, Hereford, UK. PMID- 7506293 CU - 95 SI - GENBANK/X17547 SI - GENBANK/M57741 SI - GENBANK/M57744 SO - J Gen Microbiol 1993 Nov;139 ( Pt 11):2585-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [70 medline neighbors] UI - 94064485 AU - Giles RC AU - Donahue JM AU - Hong CB AU - Tuttle PA AU - Petrites-Murphy MB AU - Poonacha KB AU - Roberts AW AU - Tramontin RR AU - Smith B AU - Swerczek TW TI - Causes of abortion, stillbirth, and perinatal death in horses: 3,527 cases (1986-1991). LA - Eng MH - Abnormalities/mortality/veterinary MH - Abortion, Veterinary/*etiology MH - Animal MH - Animals, Newborn MH - Atrophy MH - Bacterial Infections/complications/veterinary MH - Birth Injuries/mortality/veterinary MH - Cause of Death MH - Chorionic Villi/pathology MH - Dystocia/complications/veterinary MH - Edema/complications/veterinary MH - Female MH - Fetal Death/etiology/*veterinary MH - Horse Diseases/*etiology/mortality MH - Horses MH - Inflammation MH - Mycoses/complications/veterinary MH - Placenta Diseases/etiology/*veterinary MH - Pregnancy MH - Pregnancy, Ectopic/complications/veterinary MH - Pregnancy, Multiple MH - Retrospective Studies MH - Twins MH - Umbilical Cord/abnormalities MH - Virus Diseases/complications/veterinary PT - JOURNAL ARTICLE DA - 940104 DP - 1993 Oct 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1170-5 SB - M CY - UNITED STATES IP - 8 VI - 203 JC - HAV AA - Author EM - 9403 AB - Pathology case records of 3,514 aborted fetuses, stillborn foals, or foals that died < 24 hours after birth and of 13 placentas from mares whose foals were weak or unthrifty at birth were reviewed to determine the cause of abortion, death, or illness. Fetoplacental infection caused by bacteria (n = 628), equine herpesvirus (143), fungi (61), or placentitis (351), in which an etiologic agent could not be defined, was the most common diagnosis. Complications of birth, including neonatal asphyxia, dystocia, or trauma, were the second most common cause of mortality and were diagnosed in 19% of the cases (679). Other common diagnoses were placental edema or premature separation of placenta (249), development of twins (221), contracted foal syndrome (188), other congenital anomalies (160), and umbilical cord abnormalities (121). Less common conditions were placental villous atrophy or body pregnancy (81), fetal diarrhea syndrome (34), and neoplasms or miscellaneous conditions (26). A diagnosis was not established in 16% of the cases seen (585). The study revealed that leptospirosis (78) was an important cause of bacterial abortion in mares, and that infection by a nocardioform actinomycete (45) was an important cause of chronic placentitis. AD - Department of Veterinary Science, College of Agriculture, University of Kentucky, Lexington 40511. PMID- 8244867 SO - J Am Vet Med Assoc 1993 Oct 15;203(8):1170-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [92 medline neighbors] UI - 94008497 AU - Notheis WF AU - Kramer BK AU - Leser HG AU - Ruschoff J AU - Kromer EP AU - Riegger AJ TI - [A severe course of leptospirosis with acute kidney failure and extensive icterus (Weil disease)] LA - Ger MH - Aged MH - Biopsy, Needle MH - Case Report MH - English Abstract MH - Hemodialysis MH - Human MH - Jaundice/etiology MH - Kidney Failure, Acute/*etiology/therapy MH - Liver/pathology MH - Male MH - Penicillin G/administration & dosage MH - Prognosis MH - Weil's Disease/complications/*diagnosis/drug therapy RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 931115 DP - 1993 Oct 8 IS - 0012-0472 TA - Dtsch Med Wochenschr PG - 1437-41 SB - M SB - X CY - GERMANY IP - 40 VI - 118 JC - ECL AA - Author EM - 9401 AB - A 77-year-old man developed a fever up to 38.4 degrees C, with diarrhoea, acute renal failure (creatinine up to 8.7 mg/dl; urea up to 308 mg/dl) and marked jaundice (total bilirubin up to 24.3 mg/dl). In addition there was thrombocytopenia, conjunctivitis and epistaxis, as well as cerebral symptoms with somnolence and general slowing up. At first he was thought to have cholangitis resulting from previously diagnosed gall-stones, and he was therefore treated with ampicillin, 2 g two times daily, and metronidazole, 0.5 g two times daily. The fewer regressed, but the renal failure required haemodialysis and haemofiltration under strict fluid control. Endoscopy excluded obstructive jaundice, but a suspicion of inflammatory liver disease or possibly cirrhosis was raised in the differential diagnosis. Serology revealed an increased titre for Leptospira interrogans var. sejroe (1:200, later 1:1600). Liver biopsy finding was compatible with the diagnosis of leptospirosis. Because of the high inflammatory activity in the liver, 2 mega units of penicillin G were administered three times daily for six days. Gradually the renal functions and jaundice improved and, on discharge on the 36th day, the patient was again in generally good health, although creatinine and bilirubin values were still slightly elevated (1.7 mg/dl each). AD - Klinik und Poliklinik fur Innere Medizin II, Universitat Regensburg. PMID- 8404498 TT - Schwerer Verlauf einer Leptospirose mit akutem Nierenversagen und ausgepragtem Ikterus (Morbus Weil). EA - A SO - Dtsch Med Wochenschr 1993 Oct 8;118(40):1437-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 94016734 AU - Onyemelukwe NF TI - A serological survey for leptospirosis in the Enugu area of eastern Nigeria among people at occupational risk. LA - Eng MH - Abattoirs MH - Agricultural Workers' Diseases/epidemiology MH - Antibodies, Bacterial/*blood MH - Coal Mining MH - Human MH - Laboratories, Hospital MH - Laboratory Infection/epidemiology MH - Laboratory Personnel MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology MH - Male MH - Nigeria/epidemiology MH - Occupational Diseases/*epidemiology MH - Prevalence MH - Risk Factors RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 931118 DP - 1993 Oct IS - 0022-5304 TA - J Trop Med Hyg PG - 301-4 SB - M CY - ENGLAND IP - 5 VI - 96 JC - KAV AA - Author EM - 9401 AB - A serological examination of sera from 661 human volunteers in various occupations comprising 248 coal miners, 138 butchers and abattoir workers, 213 local farmers and 62 hospital laboratory personnel from various communities in Enugu and environs of eastern Nigeria was undertaken between January 1990 and March 1991. Leptospiral antibody titres of 1:100 and above were present in 89 (13.5%). The highest prevalence of antibodies to individual serovars were canicola 21 (23.6%), hardjo 17 (19.1%), pomona 13 (14.6%), icterohaemorrhagiae 11 (12.4%), pyrogenes 8 (9.0%), autumnalis 8 (9.0%) and grippotyphosa 7 (7.9%). Among the occupational groups examined, the coal miners were particularly at risk with a prevalence rate of 41 (46%), followed by the butchers/abattoir workers 26 (29.2%), farmers 18 (20.2%) and hospital laboratory personnel 4 (4.5%). AD - Department of Medical Laboratory Sciences, College of Medicine, University of Nigeria Enugu Campus. PMID- 8411305 SO - J Trop Med Hyg 1993 Oct;96(5):301-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [61 medline neighbors] UI - 94114616 AU - Hong CB AU - Donahue JM AU - Giles RC Jr AU - Petrites-Murphy MB AU - Poonacha KB AU - Roberts AW AU - Smith BJ AU - Tramontin RR AU - Tuttle PA AU - Swerczek TW TI - Equine abortion and stillbirth in central Kentucky during 1988 and 1989 foaling seasons. LA - Eng MH - Abortion, Veterinary/*epidemiology/pathology MH - Animal MH - Female MH - Fetal Death/epidemiology/pathology/*veterinary MH - Gestational Age MH - *Horse Diseases MH - *Horses MH - Kentucky/epidemiology MH - Placenta/*pathology MH - Placenta Diseases/pathology/veterinary MH - Pregnancy MH - Seasons MH - Umbilical Cord/*pathology PT - JOURNAL ARTICLE DA - 940218 DP - 1993 Oct IS - 1040-6387 TA - J Vet Diagn Invest PG - 560-6 SB - M CY - UNITED STATES IP - 4 VI - 5 JC - A2D AA - Author EM - 9404 AB - Pathologic and microbiologic examinations were performed on 1,211 aborted equine fetuses, stillborn foals, and placentas from premature foals in central Kentucky during the 1988 and 1989 foaling seasons to determine the causes of reproductive loss in the mare. Placentitis (19.4%) and dystocia-perinatal asphyxia (19.5%) were the 2 most important causes of equine reproductive loss. The other causes (in decreasing order) were contracted foal syndrome and other congenital anomalies (8.5%), twinning (6.1%), improper separation of placenta (4.7%), torsion of umbilical cord (4.5%), placental edema (4.3%), equine herpesvirus abortion (3.3%), bacteremia (3.2%), fetal diarrhea (2.7%), other placental disorders (total of 6.0%), and miscellaneous causes (1.6%). A definitive diagnosis was not established in 16.9% of the cases submitted. Streptococcus zooepidemicus, Escherichia coli, Leptospira spp., and a nocardioform actinomycete were organisms most frequently associated with bacterial placentitis, and Aspergillus spp. was the fungus most often noted in mycotic placentitis. No viral placentitis was noticed in this series. Dystocia-perinatal asphyxia was mostly associated with large foals, maiden mares, unattended deliveries, and malpresentations. The results of this study indicate that in central Kentucky, the noninfectious causes of equine reproductive loss outnumber the infectious causes by an approximate ratio of 2:1, placental disorders are slightly more prevalent than nonplacental disorders, Leptospira spp. and a nocardioform actinomycete are 2 new important abortifacient bacteria in the mare, the occurrence of contracted foal syndrome is unusually frequent, the incidence of twin abortion has sharply declined, and torsion of the umbilical cord is an important cause of abortion in the mare. AD - Livestock Disease Diagnostic Center, University of Kentucky, Lexington 40511. PMID- 8286455 SO - J Vet Diagn Invest 1993 Oct;5(4):560-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 94114614 AU - Kaufman AC AU - Greene CE AU - McGraw RA TI - Optimization of polymerase chain reaction for the detection of Borrelia burgdorferi in biologic specimens. LA - Eng MH - Animal MH - Base Sequence MH - Borrelia burgdorferi/genetics/*isolation & purification MH - Chromosomes, Bacterial MH - *Dog Diseases MH - Dogs MH - DNA Primers MH - DNA, Bacterial/analysis MH - Leptospira interrogans/genetics/isolation & purification MH - Lyme Disease/diagnosis/*veterinary MH - Molecular Sequence Data MH - Polymerase Chain Reaction/methods/*veterinary MH - Sensitivity and Specificity RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940218 DP - 1993 Oct IS - 1040-6387 TA - J Vet Diagn Invest PG - 548-54 SB - M CY - UNITED STATES IP - 4 VI - 5 JC - A2D AA - Author EM - 9404 AB - This study describes the use of a newly constructed set of primers that amplifies an 85-base pair (bp) segment of Borrelia burgdorferi chromosomal DNA. This 85-bp product is not produced when other Borrelia species, Leptospira, or other bacteria are subjected to polymerase chain reaction (PCR). We also describe a rapid method of optimizing the amplification of B. burgdorferi DNA from canine ethylenediaminetetraacetic acid-treated blood and urine samples that circumvents some of the problems encountered due to low number of spirochetes in clinical specimens and that removes inhibiting substances, which improves the PCR diagnosis of canine Lyme borreliosis. AD - Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602. PMID- 8286453 SO - J Vet Diagn Invest 1993 Oct;5(4):548-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 94089230 AU - Nakamura Y AU - Umemoto T AU - Nakatani Y AU - Namikawa I AU - Wadood A TI - Common and specific antigens of several treponemes detected by polyclonal antisera against major cellular proteins. LA - Eng MH - Animal MH - Antibodies, Bacterial MH - Antigens, Bacterial/*analysis MH - Bacterial Outer Membrane Proteins/analysis MH - Bacterial Proteins/*analysis MH - Flagella/immunology MH - Human MH - Immunoblotting MH - Mice MH - Microscopy, Immunoelectron MH - Support, Non-U.S. Gov't MH - Treponema/*immunology/ultrastructure RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE DA - 940127 DP - 1993 Oct IS - 0902-0055 TA - Oral Microbiol Immunol PG - 288-94 SB - D CY - DENMARK IP - 5 VI - 8 JC - ORA AA - Author EM - 9403 AB - Thirteen polypeptide antigens with molecular weights ranging from 34 kDa to 83 kDa were selected and their antigenic behaviors and distribution were examined in 12 strains of microorganisms including Treponema, Borrelia, Leptospira and Leptonema. Immunoblot analysis demonstrated that 45 kDa and 83 kDa polypeptides of Treponema socranskii subsp. buccale ATCC 35534, 53 kDa antigen of Treponema denticola ATCC 33520 and 44 kDa polypeptide of the strain G7201 were strain-specific. The 34, 62, 66 and 84 kDa polypeptide antigens were detected in all 8 treponemal strains examined. T. denticola ATCC 33520 and ATCC 35404 possessed 38 kDa, 48 kDa, 52 kDa and 72 kDa common polypeptide antigens. All 12 strains possessed the 84 kDa polypeptide antigen. Immunoelectron microscopy demonstrated that the 34 kDa and 38 kDa polypeptide antigens were located on the axial flagella and that other polypeptide antigens were located on the outer envelopes or wall- membrane complexes. AD - Department of Oral Microbiology, School of Dentistry, Asahi University, Gifu, Japan. PMID- 8265202 LI - D SO - Oral Microbiol Immunol 1993 Oct;8(5):288-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 94088307 AU - Savio ML AU - Pacciarini ML AU - Cinco M AU - Tagliabue S TI - Identification of Leptospira interrogans strains by monoclonal antibodies and genomic analysis. LA - Eng MH - Animal MH - Antibodies, Monoclonal MH - *Bacterial Typing Techniques MH - Blotting, Southern MH - Cattle MH - DNA, Bacterial/genetics MH - Genotype MH - Leptospira interrogans/*classification/genetics MH - Serotyping/methods MH - Support, Non-U.S. Gov't MH - Swine MH - Variation (Genetics)/genetics RN - 0 (Antibodies, Monoclonal) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940126 DP - 1993 Oct IS - 1121-7138 TA - New Microbiol PG - 315-21 SB - M CY - ITALY IP - 4 VI - 16 JC - CGC AA - Author EM - 9403 AB - A recombinant probe derived from a genomic library of serovar hardjo strain Hardjoprajitno, and a panel of serovar specific Monoclonal Antibodies (MAbs) were used for the characterization of 31 Leptospira isolates from cattle and swine. The two methods performed equally well in serovar identification except for the distinction of the genotypes hardjoprajitno and hardjobovis within serovar hardjo which could only be obtained by genomic analysis. The combination of immunological and genetic information was also useful to evaluate the degree of variability of Leptospira strains. The quality of the patterns and the sensitivity provided by a digoxigenin labelled probe were comparable to those obtained with a radioactive reagent. AD - Istituto Zooprofilattico della Lombardia e dell'Emilia, Brescia, Italy. RO - M:CNR PMID- 8264422 LR - 960123 SO - New Microbiol 1993 Oct;16(4):315-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 94081534 AU - Modric Z AU - Huber D TI - Serologic survey for leptospirae in European brown bears (Ursus arctos) in Croatia. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals, Wild MH - Animals, Zoo MH - Antibodies, Bacterial/*blood MH - *Bears MH - Croatia/epidemiology MH - Cross Reactions MH - Female MH - Leptospira interrogans/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Prevalence RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940119 DP - 1993 Oct IS - 0090-3558 TA - J Wildl Dis PG - 608-11 SB - M CY - UNITED STATES IP - 4 VI - 29 JC - KEM AA - Author EM - 9403 AB - From 1981 to 1991, sera of 42 European brown bears (Ursus arctos) from three areas in Croatia were tested for antibodies against 12 Leptospira interrogans serovars: grippotyphosa, sejroe, australis, pomona, canicola, icterohaemorrhagiae, tarassovi, saxkoebing, ballum, bataviae, poi, and hardjo. Diagnostic levels of antibody were found in 17 (40%) of 42 sera. Evidence of exposure to at least one of the serovars was found in seven of 14 free-ranging bears from the Lika region, four of 12 free-ranging bears from the Gorski Kotar region, zero of six orphaned cubs from the Gorski Kotar region, and six of 10 captive bears from the Zagreb Zoo. Based on the antibody titers, we implicated the following serovars: australis in five bears, sejroe in two bears, canicola in one bear, and icterohaemorrhagiae in one bear. There was a strong correlation between serovars implicated by this survey and serovars previously isolated from small mammals in Croatia. AD - Department of Microbiology and Infectious Diseases, Veterinary Faculty, University of Zagreb, Republic of Croatia. PMID- 8258865 SO - J Wildl Dis 1993 Oct;29(4):608-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 94081532 AU - Rim BM AU - Rim CW AU - Chang WH AU - Kakoma I TI - Leptospirosis serology in Korean wild animals. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals, Wild MH - Antibodies, Bacterial/blood MH - Bird Diseases/*epidemiology MH - Birds MH - Disease Outbreaks/prevention & control MH - Korea/epidemiology MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - *Mammals MH - Muridae MH - Prevalence MH - Rodent Diseases/epidemiology MH - Support, Non-U.S. Gov't MH - Zoonoses RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940119 DP - 1993 Oct IS - 0090-3558 TA - J Wildl Dis PG - 602-3 SB - M CY - UNITED STATES IP - 4 VI - 29 JC - KEM AA - Author EM - 9403 AB - A study was undertaken on wild animals to determine the seroprevalence of animal leptospirosis in Korea. Using the serum microagglutination test for 19 serogroups, it was shown that two of 26 rats (Rattus rattus) had antibodies to Leptospira canicola. When data for domestic animals were included, the most prevalent (nearly 50%) serogroup was Leptospira canicola. AD - College of Veterinary Medicine, Chonbuk National University, Chonju, Korea. PMID- 8258863 SO - J Wildl Dis 1993 Oct;29(4):602-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 94081523 AU - New JC Jr AU - Wathen WG AU - Dlutkowski S TI - Prevalence of Leptospira antibodies in white-tailed deer, Cades Cove, Great Smoky Mountains National Park, Tennessee, USA. LA - Eng MH - Age Factors MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*blood MH - Cattle MH - Cattle Diseases/epidemiology MH - Chi-Square Distribution MH - *Deer MH - Female MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Odds Ratio MH - Prevalence MH - Sex Factors MH - Support, Non-U.S. Gov't MH - Tennessee/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940119 DP - 1993 Oct IS - 0090-3558 TA - J Wildl Dis PG - 561-7 SB - M CY - UNITED STATES IP - 4 VI - 29 JC - KEM AA - Author EM - 9403 AB - We conducted a study of the population dynamics, movement, and diseases of white-tailed deer (Odocoileus virginianus) in Cades Cove, Great Smoky Mountains National Park, Tennessee (USA) from 1980 to 1984. During the study 590 blood samples were collected from 518 deer, with some deer recaptured one or two times. The estimated percent of the herd sampled each year ranged from 8% to 28%. We also collected serum samples from 56 cattle pastured in Cades Cove. Deer and cattle sera were tested using the microagglutination test for the presence of antibody to the following serovars of Leptospira: pomona, hardjo, grippotyphosa, icterohemorrhagiae, and canicola. One hundred and six deer (21%) were seropositive for only one of the serovars. We found that 57 (11%) of the deer had antibodies to serovar hardjo, 33 (6%) were positive for antibodies to serovar pomona, 15 (3%) were positive for antibodies to serovar icterohemorrhagiae, and one deer had antibodies to serovar canicola. Age class and sex of deer were associated with antibody presence. Adult (> or = 1.5 yr) male deer were more likely to have antibodies than the other age class and sex groups (P = 0.001). In recaptured deer, similar titers were found in samples from one deer taken 807 days apart. Titer declined below the screening dilution level (1:250) after 37 days in one deer. AD - Department of Environmental Practice, College of Veterinary Medicine, University of Tennessee, Knoxville 37901-1071. PMID- 8258854 SO - J Wildl Dis 1993 Oct;29(4):561-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 94079570 AU - McClintock CS AU - McGowan MR AU - Corney BG AU - Colley J AU - Smythe L AU - Dohnt M AU - Woodrow M TI - Isolation of Leptospira interrogans serovars hardjo and zanoni from a dairy herd in north Queensland. LA - Eng MH - Age Factors MH - Animal MH - Antibodies, Bacterial/blood MH - Bacteriuria/microbiology/*veterinary MH - Cattle MH - Cattle Diseases/epidemiology/*microbiology MH - Female MH - Leptospira interrogans/classification/immunology/*isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Prevalence MH - Queensland/epidemiology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940111 DP - 1993 Oct IS - 0005-0423 TA - Aust Vet J PG - 393-4 SB - M CY - AUSTRALIA IP - 10 VI - 70 JC - 9IE EM - 9403 AD - Department of Farm Animal Medicine and Production, University of Queensland, Kenmore. PMID- 8257323 SO - Aust Vet J 1993 Oct;70(10):393-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 94079567 AU - Dickeson D AU - Love DN TI - A serological survey of dogs, cats and horses in south-eastern Australia for leptospiral antibodies [see comments] LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Cat Diseases/*epidemiology MH - Cats MH - Cross Reactions MH - Dog Diseases/*epidemiology MH - Dogs MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospira/immunology MH - Leptospirosis/epidemiology/*veterinary MH - New South Wales/epidemiology MH - Prevalence MH - Victoria/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940111 DP - 1993 Oct IS - 0005-0423 TA - Aust Vet J PG - 389-90 SB - M CY - AUSTRALIA IP - 10 VI - 70 JC - 9IE EM - 9403 AD - Institute of Clinical Pathology & Medical Research, Westmead Hospital, New South Wales. CM - Comment in: Aust Vet J 1994 Feb;71(2):59-60 RO - M:LC2 PMID- 8257320 LR - 940727 SO - Aust Vet J 1993 Oct;70(10):389-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 94026622 AU - Nelsen S AU - Sealy DP AU - Schneider EF TI - The aseptic meningitis syndrome. LA - Eng MH - Clinical Protocols MH - Diagnosis, Differential MH - Human MH - *Meningitis, Aseptic/diagnosis/etiology/therapy MH - Meningitis, Viral/diagnosis/therapy MH - Syndrome PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 931028 DP - 1993 Oct IS - 0002-838X TA - Am Fam Physician PG - 809-15 SB - A SB - M CY - UNITED STATES IP - 5 VI - 48 JC - 3BT AA - Author EM - 9401 AB - The diagnosis and treatment of acute meningitis is a challenge for the primary care physician. Differentiating between bacterial meningitis and aseptic meningitis is not always straightforward. The aseptic meningitis syndrome is usually viral in origin, and enteroviruses account for most cases. The aseptic syndrome also may be caused by unusual bacterial organisms such as Mycobacterium tuberculosis, Leptospira species, Brucella species, Borrelia burgdorferi and others. The classic presentation consists of the acute onset of meningismus, headache, fever, malaise with pleocytosis and normal glucose and slightly elevated protein in the cerebrospinal fluid. Cerebrospinal fluid lactate and serum C-reactive protein measurements may be helpful in differentiating aseptic meningitis from treatable bacterial meningitis. Aseptic meningitis of viral origin usually responds to expectant care. Other causes of aseptic meningitis must be searched for and treated if present. AD - Self Memorial Hospital, Greenwood, South Carolina. RF - 13 PMID- 8213411 SO - Am Fam Physician 1993 Oct;48(5):809-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 94233804 AU - Zhu S AU - Chappel R AU - Amon L TI - [Restriction endonuclease analysis of Pomona serogroup of Leptospira interrogans] LA - Chi MH - Animal MH - Bacterial Typing Techniques MH - DNA Restriction Enzymes MH - DNA, Bacterial/*analysis MH - English Abstract MH - Kidney/microbiology MH - Leptospira interrogans/*classification/genetics MH - Restriction Mapping MH - Swine RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940607 DP - 1993 Oct IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 374-7 CY - CHINA IP - 5 VI - 33 JC - XNA AA - Author EM - 9408 AB - Restriction Endonuclease Analysis (REA) was performed on DNAs from the type strains of the Pomona serogroup of Leptospira interrogans by using EcoRI and HhaI restriction enzyme, and the electrophoretic patterns obtained were compared with patterns obtained from 27 isolates from pig kidneys collected at abattoirs in Victoria, which belong to Pomona serogroup previous identified by MAT. All of the isolates were identified as serovar Pomona. AD - Animal Quarantine Institute Ministry of Agriculture, Qingdao. PMID- 8178514 EA - A SO - Wei Sheng Wu Hsueh Pao 1993 Oct;33(5):374-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 94345245 AU - Lilenbaum W AU - Ribeiro V AU - Martin E AU - Bispo V TI - [Serologic study for detecting anti-Leptospira antibodies in Rattus norvegicus from Duque de Caxias, Rio de Janeiro, Brazil] LA - Por MH - Animal MH - Antibodies, Bacterial/*blood/immunology MH - Brazil/epidemiology MH - Disease Outbreaks MH - Disease Reservoirs MH - Disease Vectors MH - English Abstract MH - Female MH - Human MH - Leptospira/classification/*immunology MH - Leptospirosis/blood/epidemiology/immunology/*veterinary MH - Male MH - Rats/immunology/*microbiology MH - Rodent Diseases/blood/*epidemiology/immunology/microbiology MH - Seroepidemiologic Methods MH - Urban Population MH - Zoonoses RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940919 DP - 1993 Oct-Dec IS - 0187-4640 TA - Rev Latinoam Microbiol PG - 357-80 CY - MEXICO IP - 4 VI - 35 JC - SEP AA - Author EM - 9411 AB - Due to the high incidence of leptospirosis human cases in Duque de Caxias, state of Rio de Janeiro, the authors captured 47 rats (Rattus norvegicus) in order to search agglutinins on them. Through serological reactions, 17 positive animals (36.17%) were identified, being 16 to the serovar icterohaemorrhagiae and 1 to the serovar canicola, with titers from 1/100 to 1/400. AD - Departmento de Microbiologia e Parasitologia, Universidade Federal Fluminense. Brasil. PMID- 8066330 TT - Estudo sorologico para deteccao de anticorpos anti-leptospira em Rattus norvegicus de Duque de Caxias, Rio de Janeiro, Brasil. EA - A SO - Rev Latinoam Microbiol 1993 Oct-Dec;35(4):357-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 94011356 AU - Lachumanan R AU - Devi S AU - Cheong YM AU - Rodda SJ AU - Pang T TI - Epitope mapping of the Sta58 major outer membrane protein of Rickettsia tsutsugamushi. LA - Eng MH - Amino Acid Sequence MH - Antibodies, Bacterial/immunology MH - Antigens, Bacterial/chemistry/immunology MH - Bacterial Outer Membrane Proteins/*immunology MH - Bacterial Proteins/*immunology MH - Epitopes MH - Human MH - In Vitro MH - Molecular Sequence Data MH - Peptides/immunology MH - Rickettsia tsutsugamushi/*immunology MH - Scrub Typhus/*immunology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Bacterial Proteins) RN - 0 (Epitopes) RN - 0 (Peptides) RN - 0 (Sta58 antigen) PT - JOURNAL ARTICLE DA - 931116 DP - 1993 Oct IS - 0019-9567 TA - Infect Immun PG - 4527-31 SB - M SB - X CY - UNITED STATES IP - 10 VI - 61 JC - GO7 AA - Author EM - 9401 AB - Binding studies of 160 overlapping, synthetic octapeptides from the hydrophilic regions of the Sta58 major outer membrane protein of Rickettsia tsutsugamushi with sera from patients with scrub typhus revealed 15 immunodominant peptides which are recognized by all the sera tested. Further analysis of the specificity of peptide binding with five of these peptides indicated that the peptides showed significantly stronger binding to scrub typhus patients' sera than they did to sera from patients with other febrile illnesses common in the region, i.e., malaria, dengue fever, typhoid fever, and leptospirosis. The main antibody class binding to these peptides appears to be immunoglobulin M, and there appears to be little correlation between reactivity with peptides and antibody titers measured by the indirect immunoperoxidase test. AD - Institute of Advanced Studies, University of Malaya, Kuala Lumpur. PMID- 7691753 CU - 95 SO - Infect Immun 1993 Oct;61(10):4527-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 94116955 AU - Zhang Y AU - Li S AU - Dai B TI - [Amplified 23S rRNA gene of 52 strains of Leptospira and detection of leptospiral DNA in 55 patients by PCR] LA - Chi MH - Base Sequence MH - DNA Primers MH - DNA, Bacterial/*analysis MH - English Abstract MH - Genes, Bacterial/*genetics MH - Human MH - Leptospira interrogans/genetics/*isolation & purification MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - Support, Non-U.S. Gov't MH - Weil's Disease/diagnosis/*microbiology RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940218 DP - 1993 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 262-7 CY - CHINA IP - 3 VI - 24 JC - GEB AA - Author EM - 9404 AB - Based upon the polymerase chain reaction (PCR), We have developed a sensitive assay for Leptospira interrogans, the agent of leptospirosis. DNA amplification was carried out using primer A: 5'GATCTAATTCGCTGTAGCAGG3' and primer B: 5'ACTTTCACCCTCTATGGTCGG3'. After 30 cycles of amplification, the product could be detected by agarose gel electrophoresis. A segment (124 bp) was amplified in all strains of L. interrogans including 20 Serogroups, 49 Serovars tested, but it was not detected in Patoc I strain, Serovar patoc of Leptospira biflexa and 3055 strain of Leptonema illini (both of which are nonpathogenic). All of the serum (first time) which proved either by blood culture or MAT showed that positive rates were 100%. Leptospiral infection in humans and some domestic animals leads to one or more of a variety of manifestation and persists through a considerable duration of time. However it is relatively difficult to demonstrate the presence of leptospires in serum. The serum (second time) obtained from 55 patients with leptospirosis (6-60 days after on set) showed that PCR positive rates were 74.55% (41/55). The PCR positive rates for healthy subjects were 15% (3/20), P < 0.001. The diagnosis of leptospirosis by using PCR may become a significant addition to the routine laboratory diagnosis and a valuable technique for the investigation of leptospirosis pathogenesis. PMID- 8288193 GS - 23S rRNA EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1993 Sep;24(3):262-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 94116954 AU - Wu W AU - Dai B TI - [Restriction endonuclease analysis of leptospiral DNA from different serogroup and serovar] LA - Chi MH - Deoxyribonuclease EcoRI MH - DNA Restriction Enzymes MH - DNA, Bacterial/*analysis MH - English Abstract MH - Leptospira/*classification/isolation & purification MH - Leptospira interrogans/classification/isolation & purification MH - Restriction Mapping MH - Serotyping MH - Support, Non-U.S. Gov't RN - EC 3.1.21 (DNA Restriction Enzymes) RN - EC 3.1.21.- (Deoxyribonuclease EcoRI) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 940218 DP - 1993 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 258-61 CY - CHINA IP - 3 VI - 24 JC - GEB AA - Author EM - 9404 AB - The DNAs of different serogroups and serovars of leptospires were analyzed with seven kinds of restriction endonuclease (Bam HI, Bgl II, Cfo I, Eco RI, Hind III, Kpn I and Pst I). The results showed that there are significant differences among the leptospiral DNAs of different serovars, especially in the high molecular-weight region, but the patterns of different strains belonging to the same serovar are similar. In addition, Cfo I and Eco RI are more effective for differentiating leptospires. PMID- 8288192 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1993 Sep;24(3):258-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 94053048 AU - Leonard FC AU - Quinn PJ AU - Ellis WA AU - O'Farrell K TI - Association between cessation of leptospiruria in cattle and urinary antibody levels. LA - Eng MH - Animal MH - Antibodies, Bacterial/*urine MH - Cattle MH - *Cattle Diseases MH - Female MH - IgA/urine MH - IgG/blood/urine MH - Leptospira interrogans/*isolation & purification MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/urine/*veterinary MH - Support, Non-U.S. Gov't MH - Time Factors MH - Urine/microbiology MH - Weil's Disease/microbiology/urine/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (IgA) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 931221 DP - 1993 Sep IS - 0034-5288 TA - Res Vet Sci PG - 195-202 SB - M CY - ENGLAND IP - 2 VI - 55 JC - R7D AA - Author EM - 9402 AB - The shedding of Leptospira interrogans serovar hardjo in the urine of cattle and the local and systemic response to these organisms was monitored in experimentally and naturally infected animals. Twenty yearling heifers, 10 infected by the instillation of leptospires into the conjunctival sac (supraconjunctival route) and 10 infected intrauterinely, shed leptospires for up to 60 weeks after infection. Five of 15 naturally infected pregnant heifers with microscopic agglutination test titres > or = 1:300 continued to shed leptospires from 28 to 40 weeks after initial detection. Serovar hardjo was isolated infrequently from the urine of a further five naturally infected animals during the first eight weeks of the study but no leptospires were isolated from the remaining five animals for the duration of the study period (84 weeks). Cessation of leptospiruria in the 20 experimentally infected animals and in the five naturally infected persistent excretors was invariably associated with a sharp increase in urinary anti-leptospiral IgG and IgA antibody levels. AD - Teagasc, Moorepark Research and Development Centre, Fermoy, County Cork. PMID- 8235087 SO - Res Vet Sci 1993 Sep;55(2):195-202 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 94029888 AU - Mauermann U AU - Wiegand D AU - Manz D AU - Weiss R TI - [The use of nonpathogenic leptospira as diagnostic antigens for the diagnosis of leptospira infections in cattle] LA - Ger MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*blood MH - Antigens, Bacterial/*diagnostic use MH - Cattle MH - Cattle Diseases/*diagnosis MH - English Abstract MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 931118 DP - 1993 Sep IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 296-9 CY - GERMANY IP - 9 VI - 106 JC - 9Q8 AA - Author EM - 9401 AB - The seroprevalence of leptospira antibodies was determined in 4377 bovine sera by microagglutination assay using 11 Leptospira interrogans serovars. In 10% (439 samples) of the sera, a positive reaction was detected. These included 275 sera (62.6%) with reaction to L. grippotyphosa, 159 (36.2%) to L. saxkoebing and 5 (1.1%) sera with reactions to other serovars. Multiple reactions were found in 9.8% of the 439 positive sera, whereby the Sejroe group dominated (65%) within the possible combinations of crossreactions. To determine the suitability of nonpathogenic strains as polyvalent diagnostic antigens, two L. biflexa serovar patoc strains were compared with the above- mentioned 11 L. interrogans serovars in microagglutination testing of 1995 screen sera. The sensitivity of the test was found to be 0.3% and the specificity was 80.3%. Using the two L. patoc strains, all of the 415 positive field sera and 11 positive control sera yielded negative reactions. Based on these results, the use of L. biflexa serovar patoc cannot be recommended as polyvalent antigen in the diagnosis of bovine leptospirosis by microagglutination. AD - Staatlichen Medizinal-, Lebensmittel- und Veterinaruntersuchungsamt Mittelhessen in Giessen. PMID- 8216195 TT - Zur Nutzung apathogener Leptospiren als Suchantigene in der Diagnostik der Leptospireninfektion des Rindes. EA - A SO - Berl Munch Tierarztl Wochenschr 1993 Sep;106(9):296-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 93374839 AU - Zuerner RL AU - Herrmann JL AU - Saint Girons I TI - Comparison of genetic maps for two Leptospira interrogans serovars provides evidence for two chromosomes and intraspecies heterogeneity. LA - Eng MH - Amino Acids/biosynthesis/genetics MH - Base Sequence MH - *Chromosomes, Bacterial MH - Comparative Study MH - DNA Insertion Elements MH - DNA Replication/genetics MH - DNA, Bacterial MH - Genome, Bacterial MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - *Restriction Mapping MH - RNA, Bacterial/genetics MH - RNA, Ribosomal/genetics MH - Transcription, Genetic/genetics MH - Translation, Genetic/genetics MH - *Variation (Genetics) RN - 0 (Amino Acids) RN - 0 (DNA Insertion Elements) RN - 0 (DNA, Bacterial) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE DA - 931001 DP - 1993 Sep IS - 0021-9193 TA - J Bacteriol PG - 5445-51 SB - M CY - UNITED STATES IP - 17 VI - 175 JC - HH3 AA - Author EM - 9312 AB - Genetic maps were constructed for Leptospira interrogans serovars icterohaemorrhagiae and pomona. Previously we independently constructed physical maps of the genomes for these two serovars. The genomes of both serovars consist of a large replicon (4.4 to 4.6 Mb) and a small replicon (350 kb). Genes were localized on the physical maps by using Southern blot analysis with specific probes. Among the probes used were genes encoding a variety of essential enzymes and genes usually found near bacterial chromosomal replication origins. Most of the essential genes are on the larger replicon of each serovar. However, the smaller replicons of both serovars contain the asd gene. The asd gene encodes aspartate beta-semialdehyde dehydrogenase, an enzyme essential in amino acid and cell wall biosyntheses. The finding that both L. interrogans replicons contain essential genes suggests that both replicons are chromosomes. Comparison of the genetic maps of the larger replicons of the two serovars showed evidence of large rearrangements. These data show that there is considerable intraspecies heterogeneity in L. interrogans. AD - National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa 50010. PMID- 7690025 CU - 95 SO - J Bacteriol 1993 Sep;175(17):5445-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 94280818 AU - Squarcione S AU - Maggi P AU - Pece S AU - Lo Caputo S AU - Marcuccio L TI - Occupational risk linked to leptospirae in Apulia. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Child MH - Female MH - Horse Diseases/*transmission MH - Horses MH - Human MH - Italy MH - Leptospirosis/microbiology/*transmission/*veterinary MH - Male MH - Occupational Diseases/diagnosis/*etiology MH - Risk Factors MH - Zoonoses PT - JOURNAL ARTICLE DA - 940726 DP - 1993 Sep-Oct IS - 1120-9135 TA - Ann Ig PG - 301-3 CY - ITALY IP - 5 VI - 5 JC - AND EM - 9409 AD - Ministero della Sanita, Roma. PMID- 7516674 CU - 95 SO - Ann Ig 1993 Sep-Oct;5(5):301-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 93317003 AU - Kreisberg RA TI - Clinical problem-solving. An abundance of options [see comments] LA - Eng MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Fever/etiology MH - Human MH - Leptospirosis/complications/*diagnosis MH - Male MH - Skin Diseases, Infectious/complications/diagnosis PT - JOURNAL ARTICLE DA - 930809 DP - 1993 Aug 5 IS - 0028-4793 TA - N Engl J Med PG - 413-6 SB - A SB - M SB - X CY - UNITED STATES IP - 6 VI - 329 JC - NOW EM - 9310 AD - University of Alabama, Birmingham 35294-0012. CM - Comment in: N Engl J Med 1993 Dec 30;329(27):2040-1 CM - Comment in: N Engl J Med 1993 Dec 30;329(27):2041 RO - M:CNR RO - M:LC2 PMID- 8326976 LR - 940323 SO - N Engl J Med 1993 Aug 5;329(6):413-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 94014964 AU - Gravekamp C AU - Van de Kemp H AU - Franzen M AU - Carrington D AU - Schoone GJ AU - Van Eys GJ AU - Everard CO AU - Hartskeerl RA AU - Terpstra WJ TI - Detection of seven species of pathogenic leptospires by PCR using two sets of primers. LA - Eng MH - Base Sequence MH - *DNA Primers MH - DNA, Bacterial/analysis MH - Gene Library MH - Human MH - Leptospira/classification/*isolation & purification/pathogenicity MH - Leptospirosis/diagnosis/microbiology MH - Molecular Sequence Data MH - *Polymerase Chain Reaction MH - Support, Non-U.S. Gov't RN - 0 (DNA Primers) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 931124 DP - 1993 Aug IS - 0022-1287 TA - J Gen Microbiol PG - 1691-700 SB - M CY - ENGLAND VI - 139 ( Pt 8) JC - I87 AA - Author EM - 9401 AB - Two sets of primers derived from genomic DNA libraries of Leptospira serovars icterohaemorrhagiae (strain RGA) and bim (strain 1051) enabled the amplification by PCR of target DNA fragments from leptospiral reference strains belonging to all presently described pathogenic Leptospira species. The icterohaemorrhagiae-derived primers (G1/G2) enabled amplification of DNA from L. interrogans, L. borgpetersenii, L. weilii, L. noguchii, L. santarosai and L. meyeri, whereas the bim- derived primers (B64-I/B64-II) enabled the amplification of L. kirschneri. Southern blot and DNA sequence analysis revealed inter- species DNA polymorphism within the region spanned by primers G1 and G2 between L. interrogans and various other Leptospira species. Using a mixture of primer sets G1/G2 and B64-I/B64-II, leptospires of serovars icterohaemorrhagiae, copenhageni, hardjo, pomona, grippotyphosa and bim were detected in serum samples collected from patients during the first 10 days after the onset of illness. AD - NH Swellengrebel Laboratory for Tropical Hygiene, Royal Tropical Institute, WHO/FAO Collaborating Centre for Reference and Research on Leptospirosis, Amsterdam, The Netherlands. PMID- 8409911 SO - J Gen Microbiol 1993 Aug;139 ( Pt 8):1691-700 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 94002784 AU - Shaked Y AU - Shpilberg O AU - Samra D AU - Samra Y TI - Leptospirosis in pregnancy and its effect on the fetus: case report and review. LA - Eng MH - Abortion/etiology MH - Adult MH - Case Report MH - Female MH - Fetus/microbiology MH - Human MH - Infant, Newborn MH - Leptospirosis/*complications MH - Pregnancy MH - *Pregnancy Complications, Infectious MH - *Pregnancy Outcome PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW OF REPORTED CASES DA - 931028 DP - 1993 Aug IS - 1058-4838 TA - Clin Infect Dis PG - 241-3 SB - M CY - UNITED STATES IP - 2 VI - 17 JC - A4J AA - Author EM - 9401 AB - We report the case of a pregnant woman with leptospirosis who gave birth to a healthy baby. We also review 15 previously reported cases of leptospirosis in pregnancy. Of these 15 cases, eight women had abortions, two delivered healthy babies, and four delivered babies who had signs of active leptospirosis; in one case, the fate of the fetus was not stated. It appears that women are more likely to spontaneously abort if leptospirosis occurs in the early months of pregnancy. Since congenital infection is rare, leptospirosis should not necessarily be considered an indication to terminate pregnancy. Increased awareness of the possibility of leptospirosis for pregnant women who live in areas where the disease is endemic is of utmost importance for early detection and treatment of the disease and, thus, for the safety of the fetus. AD - Department of Internal Medicine F. Beilinson Medical Center, Petach Tikvah, Israel. RF - 16 PMID- 8399874 SO - Clin Infect Dis 1993 Aug;17(2):241-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 93380997 AU - Kim IS AU - Seong SY AU - Woo SG AU - Choi MS AU - Kang JS AU - Chang WH TI - Rapid diagnosis of scrub typhus by a passive hemagglutination assay using recombinant 56-kilodalton polypeptides. LA - Eng MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial/*immunology MH - Base Sequence MH - Fluorescent Antibody Technique MH - *Hemagglutination Tests MH - Human MH - IgM/analysis MH - Molecular Sequence Data MH - Recombinant Proteins/immunology MH - Rickettsia tsutsugamushi/*immunology MH - Scrub Typhus/*diagnosis MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (IgM) RN - 0 (Recombinant Proteins) PT - JOURNAL ARTICLE DA - 931008 DP - 1993 Aug IS - 0095-1137 TA - J Clin Microbiol PG - 2057-60 SB - M CY - UNITED STATES IP - 8 VI - 31 JC - HSH AA - Author EM - 9312 AB - The genes encoding the 56-kDa polypeptides were amplified by polymerase chain reaction from the genomic DNAs of three serotypes of Rickettsia tsutsugamushi, Gilliam, Karp, and Boryong. The amplified products were cloned into expression vector pIH821, and the recombinant antigens were expressed in Escherichia coli as fusion proteins with maltose-binding protein. The recombinant 56-kDa polypeptides were purified by affinity chromatography for the sensitization of sheep erythrocytes. The recombinant 56-kDa polypeptides were evaluated with 89 serum specimens from health blood donors, 94 serum specimens from scrub typhus patients, and 31 serum specimens from patients with other febrile diseases by a passive hemagglutination assay (PHA). Among the scrub typhus patients diagnosed by indirect immunofluorescent-antibody testing, the antibodies to R. tsutsugamushi were detected in 93 patients (99%). One serum specimen from a healthy person showed a false- positive reaction by this method. The recombinant PHA showed no cross- reactions with sera obtained from other febrile patients with diseases such as murine typhus, hemorrhagic fever with renal syndrome, and leptospirosis. In conclusion, this recombinant PHA could be substituted for the conventional indirect immunofluorescent-antibody test and the immunoperoxidase test. AD - Department of Microbiology, Seoul National University College of Medicine, Republic of Korea. PMID- 8370730 SI - GENBANK/L04956 SO - J Clin Microbiol 1993 Aug;31(8):2057-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 93364813 AU - Bernard WV TI - Leptospirosis. LA - Eng MH - *Abortion, Veterinary/microbiology MH - Animal MH - Animals, Newborn MH - Eye Infections, Bacterial/microbiology/veterinary MH - Female MH - Fetal Death/microbiology/*veterinary MH - *Horse Diseases/microbiology MH - Horses MH - Leptospira/*physiology MH - Leptospirosis/microbiology/*veterinary MH - Male MH - Pregnancy MH - Uveitis/microbiology/veterinary PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 930930 DP - 1993 Aug IS - 0749-0739 TA - Vet Clin North Am Equine Pract PG - 435-44 SB - M CY - UNITED STATES IP - 2 VI - 9 JC - CEP AA - Author EM - 9312 AB - Equine clinical leptospirosis has been primarily related to uveitis and the often recurrent sequelae of ocular changes. Reports of equine hepatic and renal involvement are sporadic. More recently, serovar bratislava has been identified as a host-adapted serovar in the horse. More significantly, reports of equine abortion and stillbirth have become more frequent in the literature. This is more than likely a result of improved diagnostic techniques, not of increased prevalence of disease. In addition to abortion, equine neonatal disease is becoming more frequently recognized in association with leptospira infection. Whether leptospiral infection results in abortion or diseased foals may depend upon the stage of gestation when the mare is exposed and host immune status. Antibiotic of choice for treatment of equine leptospirosis remains speculative, as specific equine studies have not been performed. Extrapolation from other species suggests that the use of streptomycin remains a good choice of therapy for the chronic shedding state and may be used in combination with other antimicrobials for treatment of acute disease. Penicillin or potentiated penicillins and tetracycline at appropriate to high end dosages are logical choices for the treatment of acute leptospirosis. AD - Rood and Riddle Equine Hospital, Lexington, Kentucky. RF - 89 PMID- 8358656 SO - Vet Clin North Am Equine Pract 1993 Aug;9(2):435-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 94014963 AU - Hookey JV TI - Characterization of Leptospiraceae by 16S DNA restriction fragment length polymorphisms. LA - Eng MH - Base Sequence MH - Deoxyribonuclease BamHI/metabolism MH - Deoxyribonuclease EcoRI/metabolism MH - DNA, Bacterial/genetics MH - DNA, Ribosomal MH - Leptospiraceae/*classification/genetics MH - Molecular Sequence Data MH - *Polymorphism, Restriction Fragment Length MH - RNA, Bacterial/genetics MH - RNA, Ribosomal, 16S/*genetics RN - EC 3.1.21.- (Deoxyribonuclease BamHI) RN - EC 3.1.21.- (Deoxyribonuclease EcoRI) RN - 0 (DNA, Bacterial) RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 931124 DP - 1993 Aug IS - 0022-1287 TA - J Gen Microbiol PG - 1681-9 SB - M CY - ENGLAND VI - 139 ( Pt 8) JC - I87 AA - Author EM - 9401 AB - Chromosomal DNA from 37 Leptospiracae representing genetic species, groups and reference strains together with five leptospire isolates and Escherichia coli were digested with the restriction endonucleases BamHI, ClaI and EcoRI. The Southern blots were hybridized with a biotinylated E. coli 1.5 kb 16S rDNA probe and gave 36 reproducible and unique patterns. With the exception of the type strain (Leptospira interrogans serovar icterohaemorrhagiae RGA) and neotype strain (serovar icterohaemorrhagiae Ictero no. 1) all the species and taxa examined could be differentiated from each other on the basis of their BamHI, ClaI and EcoRI restriction fragment length polymorphisms (RFLP). L. interrogans and L. borgpetersenii reference strains were heterogeneous, whereas Leptonema illini and L. parva incertae sedis were distinct and separate. Strains representing L. biflexa sensu lato presented divergent RFLP patterns. A porcine isolate was identified to be L. interrogans pomona Pomona. AD - PHLS Leptospira Reference Laboratory, FAO/WHO Collaborating Centre, County Hospital, Hereford, UK. PMID- 7691982 CU - 95 SO - J Gen Microbiol 1993 Aug;139 ( Pt 8):1681-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [58 medline neighbors] UI - 94012125 AU - Bernard WV AU - Williams D AU - Tuttle PA AU - Pierce S TI - Hematuria and leptospiruria in a foal. LA - Eng MH - Animal MH - Animals, Newborn MH - Antibodies, Bacterial/blood MH - Bacteriuria/diagnosis/microbiology/*veterinary MH - Case Report MH - Female MH - Follow-Up Studies MH - Hematuria/diagnosis/*veterinary MH - Horse Diseases/*diagnosis/microbiology MH - Horses MH - Leptospira/immunology/*isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - Placenta/microbiology MH - Pregnancy MH - Pregnancy Complications, Infectious/diagnosis/veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 931104 DP - 1993 Jul 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 276-8 SB - M CY - UNITED STATES IP - 2 VI - 203 JC - HAV AA - Author EM - 9401 AB - A Thoroughbred foal that was born after 305 days of gestation was referred 6 hours after birth. On initial examination, the foal was alert, but weak and unable to stand. Heart rate was 150 beats/min, respiratory rate was 48 breaths/min, and rectal temperature was 33 C. Leukocytosis was detected (26,000 WBC/microliters). Dysuria and passage of red urine was observed approximately 30 hours after admission. Urine collected by free catch had a 3+ reaction for blood on dipstick analysis. Examination of Warthin Starry-stained sections of allantochorion revealed organisms morphologically characteristic of leptospira spp along the chorion. Results of direct fluorescent antibody tests on section of placenta were positive for Leptospira spp. Direct fluorescent antibody testing identified leptospires in the urine of the foal. Sera from mare and foal were tested for antibodies against Leptospira spp by use of the microscopic agglutination test. High titers were identified in serum from the mare and foal. AD - Rood and Riddle Equine Hospital, Lexington, KY 40580. PMID- 8407490 SO - J Am Vet Med Assoc 1993 Jul 15;203(2):276-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [72 medline neighbors] UI - 93348567 AU - Pekelder JJ AU - Westenbrink F AU - Vellema P AU - Peterse DJ AU - Bokhout BA AU - Franken P TI - [Serological study of the occurrence of L. hardjo in sheep in The Netherlands] LA - Dut MH - Animal MH - Antibodies, Bacterial/*isolation & purification MH - English Abstract MH - Leptospira interrogans/*immunology MH - Netherlands/epidemiology MH - Seroepidemiologic Methods MH - Sheep/immunology/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930909 DP - 1993 Jul 15 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 433-5 SB - M CY - NETHERLANDS IP - 13 VI - 118 JC - VRY AA - Author EM - 9311 AB - Sheep (3918) from 137 farms in the regions of North-, West- and Mid- Netherlands and Gelderland were serologically investigated for the presence of antibodies against Leptospira hardjo. Antibodies were detected in 3.3% of the sheep. There were large regional differences with respect to both the percentage of positive sheep and the percentage of positive flocks. All sera from sheep in Gelderland were negative. In West- en Mid-Netherlands there were 0.9 and 6.5% positive sera, respectively, and 19.4 and 32.7% positive flocks. The percentage of positive sheep per positive flocks varied from 1 tot 51.6. Serological positive sheep were from farms with and without cattle. On farms with cattle, there was no clear relationship between serologically sheep and the presence of hardjo antibodies in cattle. It thus seems plausible that sheep can be infected with hardjo independently of cattle. AD - Gezondheidsdienst voor Dieren in West- en Midden-Nederland, Gouda. PMID- 8346509 TT - Een serologisch onderzoek naar het voorkomen van L. hardjo bij schapen in Nederland. EA - A SO - Tijdschr Diergeneeskd 1993 Jul 15;118(13):433-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [8 protein links] [4 nucleotide links] [113 medline neighbors] UI - 93342089 AU - Ralph D AU - McClelland M TI - Intervening sequence with conserved open reading frame in eubacterial 23S rRNA genes. LA - Eng MH - Amino Acid Sequence MH - Base Sequence MH - Comparative Study MH - Conserved Sequence MH - Genes, Bacterial/*genetics MH - Introns/*genetics MH - Leptospira/*genetics MH - Molecular Sequence Data MH - Open Reading Frames/*genetics MH - RNA Processing, Post-Transcriptional MH - RNA, Ribosomal, 23S/*genetics MH - Sequence Homology, Amino Acid MH - Sequence Homology, Nucleic Acid MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Variation (Genetics) RN - 0 (RNA, Ribosomal, 23S) PT - JOURNAL ARTICLE ID - AI34829/AI/NIAID ID - HG00456/HG/NCHGR ID - AI32644/AI/NIAID DA - 930830 DP - 1993 Jul 15 IS - 0027-8424 TA - Proc Natl Acad Sci U S A PG - 6864-8 SB - M SB - X CY - UNITED STATES IP - 14 VI - 90 JC - PV3 AA - Author EM - 9311 AB - An intervening sequence (IVS) occurred in the 23S rRNA genes (rrl) of some, but not all, strains of four species of the spirochete genus Leptospira and was absent from strains in three other species. The IVS varied in size from 485 to 759 base pairs and replaced bases 1224-1245 in both copies of rrl. The two ends of each IVS shared 22-35 bases of complementarity that could form a stable double helix. The presence of an IVS correlated with a cleaved mature 23S rRNA that probably results from removal of the IVS without religation. The 3' site of cleavage was mapped within the inverted repeat of the IVS. An open reading frame of 121-133 amino acids was conserved in the IVS in all four species, oriented so that the sense strand was in the rRNA transcript. When the open reading frames were compared between species, they predicted polypeptides that showed between 51% and 78% amino acid conservation and similar DNA sequence conservation, indicating selection for protein function. AD - California Institute of Biological Research, La Jolla 92037. PMID- 8341711 SI - GENBANK/X14249 SO - Proc Natl Acad Sci U S A 1993 Jul 15;90(14):6864-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 94022109 AU - Mohammedi I AU - Chaumentin G AU - Sab JM AU - Dubois JM AU - Mignot F AU - Robert D TI - [Acute respiratory distress syndrome caused by intra-alveolar hemorrhage in leptospirosis (letter)] LA - Fre MH - Acute Disease MH - Adult MH - Case Report MH - Human MH - Male MH - Respiratory Distress Syndrome, Adult/*etiology MH - Weil's Disease/*complications PT - LETTER DA - 931027 DP - 1993 Jul 3-10 IS - 0755-4982 TA - Presse Med PG - 1148-9 SB - M SB - X CY - FRANCE IP - 24 VI - 22 JC - PMT EM - 9401 PMID- 8415477 TT - Syndrome de detresse respiratoire aigue par hemorragie intra-alveolaire au cours d'une leptospirose. SO - Presse Med 1993 Jul 3-10;22(24):1148-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 93293337 AU - Scocchi M AU - Romeo D AU - Cinco M TI - Antimicrobial activity of two bactenecins against spirochetes. LA - Eng MH - Anti-Infective Agents/metabolism/*pharmacology MH - Borrelia burgdorferi/*drug effects/metabolism MH - Leptospira/*drug effects/metabolism MH - Microbial Sensitivity Tests MH - Peptides, Cyclic/metabolism/*pharmacology MH - Support, Non-U.S. Gov't RN - 0 (Anti-Infective Agents) RN - 0 (Peptides, Cyclic) RN - 116229-36-8 (bactenecin) PT - JOURNAL ARTICLE DA - 930722 DP - 1993 Jul IS - 0019-9567 TA - Infect Immun PG - 3081-3 SB - M SB - X CY - UNITED STATES IP - 7 VI - 61 JC - GO7 AA - Author EM - 9309 AB - Bac5 and Bac7 are antimicrobial peptides of bovine neutrophils that act on enteric gram-negative bacteria. We report here that these two peptides immobilize and kill Leptospira interrogans and Leptospira biflexa with MBCs of 6 to 25 micrograms/ml. Conversely, although both peptides bind to Borrelia burgdorferi, the organism is resistant to their action. AD - Department of Biochemistry, Biophysics and Macromolecular Biochemistry, University of Trieste, Italy. PMID- 8514417 SO - Infect Immun 1993 Jul;61(7):3081-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 93355723 AU - Gollop JH AU - Katz AR AU - Rudoy RC AU - Sasaki DM TI - Rat-bite leptospirosis. LA - Eng MH - Animal MH - Animal Diseases/microbiology MH - *Bites and Stings MH - Case Report MH - Child MH - Female MH - Human MH - Leptospira interrogans/isolation & purification MH - *Rats/microbiology MH - Weil's Disease/*transmission/veterinary MH - Zoonoses/*transmission PT - JOURNAL ARTICLE DA - 930913 DP - 1993 Jul IS - 0093-0415 TA - West J Med PG - 76-7 SB - A SB - M CY - UNITED STATES IP - 1 VI - 159 JC - XN5 EM - 9311 AD - Preventive Medicine Residency Program, University of Hawaii School of Public Health, Honolulu. PMID- 8351916 SO - West J Med 1993 Jul;159(1):76-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [2 protein links] [1 nucleotide link] [160 medline neighbors] UI - 93308103 AU - Haake DA AU - Champion CI AU - Martinich C AU - Shang ES AU - Blanco DR AU - Miller JN AU - Lovett MA TI - Molecular cloning and sequence analysis of the gene encoding OmpL1, a transmembrane outer membrane protein of pathogenic Leptospira spp. LA - Eng MH - Amino Acid Sequence MH - Bacterial Outer Membrane Proteins/*genetics/isolation & purification MH - Base Sequence MH - Cloning, Molecular MH - Comparative Study MH - Genes, Structural, Bacterial/*genetics MH - Leptospira/*genetics/pathogenicity/ultrastructure MH - Molecular Sequence Data MH - Oligonucleotide Probes MH - Protein Conformation MH - Restriction Mapping MH - Sequence Analysis, DNA MH - Sequence Homology, Amino Acid MH - Subcellular Fractions/chemistry MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Support, U.S. Gov't, P.H.S. MH - Virulence/genetics RN - 0 (ompL1 protein) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Oligonucleotide Probes) PT - JOURNAL ARTICLE ID - AI-21352/AI/NIAID ID - AI-29733/AI/NIAID ID - 5-T32-AI07323/AI/NIAID ID - + DA - 930730 DP - 1993 Jul IS - 0021-9193 TA - J Bacteriol PG - 4225-34 SB - M CY - UNITED STATES IP - 13 VI - 175 JC - HH3 AA - Author EM - 9310 AB - Pathogenic Leptospira spp. are spirochetes that have a low transmembrane outer membrane protein content relative to that of enteric gram-negative bacteria. In a previous study we identified a 31- kDa surface protein that was present in strains of Leptospira alstoni in amounts which correlated with the outer membrane particle density observed by freeze fracture electron microscopy (D. A. Haake, E. M. Walker, D. R. Blanco, C. A. Bolin, J. N. Miller, and M. A. Lovett, Infect. Immun. 59:1131-1140, 1991). The N-terminal amino acid sequence was used to design a pair of oligonucleotides which were utilized to screen a lambda ZAP II library containing EcoRI fragments of L. alstoni DNA. A 2.5-kb DNA fragment which contained the entire structural ompL1 gene was identified. The structural gene deduced from the sequence of this DNA fragment would encode a 320-amino-acid polypeptide with a 24- amino-acid leader peptide and a leader peptidase I cleavage site. Processing of OmpL1 results in a mature protein with a predicted molecular mass of 31,113 Da. Secondary-structure prediction identified repeated stretches of amphipathic beta-sheets typical of outer membrane protein membrane-spanning sequences. A topological model of OmpL1 containing 10 transmembrane segments is suggested. A recombinant OmpL1 fusion protein was expressed in Escherichia coli in order to immunize rabbits with the purified protein. Upon Triton X-114 extraction of L. alstoni and phase separation, anti-OmpL1 antiserum recognized a single band on immunoblots of the hydrophobic detergent fraction which was not present in the hydrophilic aqueous fraction. Immunoelectron microscopy with anti-OmpL1 antiserum demonstrates binding to the surface of intact L. alstoni. DNA hybridization studies indicate that the ompL1 gene is present in a single copy in all pathogenic Leptospira species that have been tested and is absent in nonpathogenic Leptospira species. OmpL1 may be the first spirochetal transmembrane outer membrane protein for which the structural gene has been cloned and sequenced. AD - Division of Infectious Diseases, West Los Angeles Veterans Affairs Medical Center, California 90073. PMID- 8320237 SI - GENBANK/L13284 SO - J Bacteriol 1993 Jul;175(13):4225-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 94055029 AU - Shin SJ AU - Chang YF AU - Jacobson RH AU - Shaw E AU - Lauderdale TL AU - Appel MJ AU - Lein DH TI - Cross-reactivity between B. burgdorferi and other spirochetes affects specificity of serotests for detection of antibodies to the Lyme disease agent in dogs. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/biosynthesis/*immunology MH - Blotting, Western/veterinary MH - Borrelia burgdorferi/*immunology MH - Cross Reactions MH - Dog Diseases/*diagnosis/immunology MH - Dogs MH - Electrophoresis, Polyacrylamide Gel/veterinary MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Lyme Disease/diagnosis/immunology/*veterinary MH - Sensitivity and Specificity MH - Spirochaetales/*immunology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 931203 DP - 1993 Jul IS - 0378-1135 TA - Vet Microbiol PG - 161-74 SB - M CY - NETHERLANDS IP - 1-2 VI - 36 JC - XBW AA - Author EM - 9402 AB - Western immunoblots, the kinetics-based enzyme-linked immunosorbent assay (KELA), and the microagglutination test were used to evaluate cross-reactivity among antibodies to serovars of Leptospira interrogans (leptospiral serovars), and B. burgdorferi from naturally infected dogs, and to Serpulina (Treponema) hyodysenteriae from vaccinated rabbits. Whole-cell lysates from Borrelia spp., leptospiral serovars, and Serpulina spp. were used for SDS-PAGE, western blots, and KELA. Crossreactivity occurred between the antibodies to B. burgdorferi and leptospiral serovars when tested on the heterologous antigens. Antibodies to leptospiral serovars tended to cross-react more strongly with antigens of B. burgdorferi spp. than did antibodies to B. burgdorferi when tested against antigens of leptospiral serovars. The antibodies against B. burgdorferi showed a lesser degree of cross- reactivity to the antigens of S. hyodysenteriae and S. innocens than they did to leptospiral serovars. We conclude that cross-reactivity occurs between B. burgdorferi and leptospiral serovars. Validation and interpretation of ELISA tests for detection of antibody activity to whole cell lysates of the Lyme agent must take this cross-reactivity into consideration. Conversely, dogs infected with the Lyme agent do not show significant cross-reactivity in the microagglutination test for antibody to the leptospiral serovars. AD - Diagnostic Laboratory, College of Veterinary Medicine, Cornell University, Ithaca, NY 14851-0786. PMID- 8236777 SO - Vet Microbiol 1993 Jul;36(1-2):161-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 94055026 AU - Nicholson VM AU - Prescott JF TI - Outer membrane proteins of three pathogenic Leptospira species. LA - Eng MH - Animal MH - Antigens, Bacterial/biosynthesis/immunology MH - Bacterial Outer Membrane Proteins/biosynthesis/*immunology MH - Cell Membrane/drug effects/enzymology MH - Electrophoresis, Polyacrylamide Gel MH - Immunoblotting MH - Iron/metabolism MH - Leptospira/*chemistry/classification/immunology/ultrastructure MH - Serine Proteinases/pharmacology MH - Serotyping MH - Support, Non-U.S. Gov't MH - Swine RN - EC 3.4.21 (Serine Proteinases) RN - EC 3.4.21.64 (Endopeptidase K) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 7439-89-6 (Iron) PT - JOURNAL ARTICLE DA - 931203 DP - 1993 Jul IS - 0378-1135 TA - Vet Microbiol PG - 123-38 SB - M CY - NETHERLANDS IP - 1-2 VI - 36 JC - XBW AA - Author EM - 9402 AB - The outer membrane proteins of seven reference strains of pathogenic Leptospira (L. alstoni serovar grippotyphosa, L. borgpetersenii serovar hardjo, and L. interrogans serovars autumnalis, bratislava, canicola, icterohaemorrhagiae, and pomona) were investigated to identify common surface-exposed outer membrane proteins. Sodium dodecyl sulfate- polyacrylamide gel electrophoresis of sodium-N-lauroylsarcosinate- insoluble outer membrane enriched fractions of the reference serovars and two field isolates of serovars hardjo and pomona revealed six common protein bands with approximate molecular masses of 77, 66, 42, 35.5, 24, and 18 kDa. At times the 35.5 kDa endoflagellar band resolved into two distinct bands, 35.5 kDa and 34 kDa. Immunoblotting of the same fractions using rabbit leptospiral antibodies showed six bands to be common (66, 59.5, 44, 42, 35.5, and 18 kDa). The 44 kDa band stained poorly with Coomassie blue but prominently by immunoblotting. Four reference strains (serovars bratislava, canicola, icterohaemorrhagiae, pomona), and two field isolates of serovar pomona and one of serovar bratislava were grown in low iron media to which the iron chelators 2,2'-dipyridyl or ethylenediaminehydroxyphenylacetic acid were added. No iron-dependent expression of outer membrane proteins was observed. The only difference observed between the outer membrane proteins when reference serovars of canicola or pomona were grown in dialysis bags in the peritoneum of swine or in vitro was the loss of the 77 kDa band from in vivo grown organisms. Treatment of whole leptospires with proteinase K did not remove the 77, 66, 59.5, or 42 kDa protein; these proteins may not be surface expressed or are inaccessible to the proteinase K. The 44 kDa band could not be evaluated by this method and the 18 kDa band was proteinase K resistant. AD - Department of Veterinary Microbiology and Immunology, University of Guelph, Ont., Canada. PMID- 8236774 CU - 96 SO - Vet Microbiol 1993 Jul;36(1-2):123-38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [79 medline neighbors] UI - 94036064 AU - Philpott M TI - The dangers of disease transmission by artificial insemination and embryo transfer [published erratum appears in Br Vet J 1994 Mar- Apr;150(2):209] LA - Eng MH - Animal MH - Animal Diseases/microbiology/*transmission MH - Bacterial Infections/transmission/veterinary MH - Cattle MH - Embryo Transfer/adverse effects/*veterinary MH - Horses MH - Insemination, Artificial/adverse effects/*veterinary MH - Risk Factors MH - Sheep MH - Swine MH - Virus Diseases/transmission/veterinary PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, ACADEMIC DA - 931202 DP - 1993 Jul-Aug IS - 0007-1935 TA - Br Vet J PG - 339-69 CY - ENGLAND IP - 4 VI - 149 JC - B5C AA - Author EM - 9402 AB - This review summarizes the major infectious diseases of the three major agricultural species (cattle, sheep and pigs) and horses, and presents the evidence for and against the possibility of infectious agents being transmitted between animals via the venereal route or by the use of semen or early embryos in commercial artificial insemination (AI) or embryo transfer (ET). Cattle feature most prominently in the widespread distribution of frozen semen, and national and international organizations have set out guidelines to work towards disease-free bull studs with semen free from potential pathogens. With the control of major epizootic diseases, attention has been focused on such diseases as IBR, BVD and blue tongue, where clinical signs are rarely evident but the detection of virus in semen is of great importance. New information on the relevance of bacterial disease such as Mycobacterium paratuberculosis, campylobacteriosis and leptospirosis is reviewed, along with details of the mycoplasma and ureaplasma species of the bull's genital tract. Bovine spongiform encephalopathy (BSE) has attracted much research and semen is not regarded as a source of infection. New work on the pathogenesis of a number of diseases and the use of new biotechnology in diagnosis is included. The International Embryo Transfer Society (IETS) has encouraged a great deal of experimental work--much originating in Canada--on the risk of transmission of disease from donors to recipients via a 7-day-old blastocyst. There has been much success in demonstrating that with an approved protocol of handling the embryos, to date there is very little danger in disease transmission with both viruses and bacteria. The mycoplasma group appear more intractable and the role of BSE is still being evaluated. In sheep, scrapie, Brucella ovis infection and blue tongue feature in current work. In the pig there is a surge in international movement of pig semen, and Aujeszky's disease and the new so-called Blue Ear disease feature prominently. Much work is in progress on infectious agents likely to be found in the semen of stallions, with an expanding trade in the international movement of chilled and frozen semen. Equine embryo transfer experiments are hampered by the very limited number of embryos available. Reference is also made to the further risk of disease transmission by in vitro manipulated embryos. AD - Avoncroft Cattle Breeders Ltd, Sugarbrook, Stoke Prior, Bromsgrove, Worcestershire. RF - 198 RO - M:MWS PMID- 8221041 LR - 940817 SO - Br Vet J 1993 Jul-Aug;149(4):339-69 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [58 medline neighbors] UI - 94025460 AU - Poonacha KB AU - Donahue JM AU - Giles RC AU - Hong CB AU - Petrites-Murphy MB AU - Smith BJ AU - Swerczek TW AU - Tramontin RR AU - Tuttle PA TI - Leptospirosis in equine fetuses, stillborn foals, and placentas. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Female MH - Fetal Death/microbiology/pathology/*veterinary MH - Fetal Diseases/microbiology/pathology/*veterinary MH - Horse Diseases/*pathology MH - Horses MH - Kidney/pathology MH - Leptospira interrogans/immunology MH - Leptospirosis/microbiology/pathology/*veterinary MH - Liver/pathology MH - Placenta Diseases/microbiology/pathology/*veterinary MH - Pregnancy MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 931104 DP - 1993 Jul IS - 0300-9858 TA - Vet Pathol PG - 362-9 SB - M CY - UNITED STATES IP - 4 VI - 30 JC - XBQ AA - Author EM - 9401 AB - Leptospirosis was diagnosed in 51 equine fetuses and 16 stillborn foals with gestational ages from 3 1/2 to 11 months. Diagnosis was based on one or more of the following: positive fetal antibody titer, positive fluorescent antibody test, demonstration of spirochetes in kidney and/or placental sections stained by the Warthin-Starry technique, high leptospiral titers in aborting mares, or isolation of Leptospira spp. from fetal organs. Gross lesions were observed in 80.3% of the fetuses, stillborn foals, and placentas. Gross placental lesions included nodular cystic allantoic masses, edema, areas of necrosis of the chorion, and necrotic mucoid exudate coating the chorion. The liver (23 cases) was enlarged, mottled, and pale to yellow. The kidneys (seven cases) were swollen and edematous with pale white radiating streaks in cortex and medulla. Microscopic lesions were observed in 96% of fetuses, stillborn foals, and placentas. Placental lesions consisted of thrombosis, vasculitis, mixed inflammatory cell infiltration of the stroma and villi, cystic adenomatous hyperplasia of allantoic epithelium, and villous necrosis and calcification. Fetal lesions included hepatocellular dissociation, mixed leukocytic infiltration of the portal triads, giant cell hepatopathy, suppurative and nonsuppurative nephritis, pulmonary hemorrhages, pneumonia, and myocarditis. Spirochetes were demonstrated with the Warthin-Starry stain in the allantochorion and/or kidney of 69 of the 71 cases. Using the direct fluorescent antibody technique, 56/60 cases tested positively for leptospires. Leptospires were isolated from fetal tissues in 20/42 cases. Sixteen of the isolates were identified by restriction enzyme analysis as Leptospira interrogans serogroup Pomona serovar kennewicki; case Nos. 36 and 41 were serovar grippotyphosa.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Veterinary Science, College of Agriculture, University of Kentucky, Lexington. PMID- 8212458 SO - Vet Pathol 1993 Jul;30(4):362-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 94346130 AU - Gol'denshtein ZA AU - Reznikov MF TI - [Human diseases caused by leptospirae of the canicola serogroup in the Krasnodar Territory] LA - Rus MH - Adult MH - Agricultural Workers' Diseases/epidemiology/etiology MH - Animal MH - Antibodies, Bacterial/blood MH - Case Report MH - Disease Outbreaks/statistics & numerical data MH - Disease Vectors MH - Dogs MH - English Abstract MH - Human MH - *Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/*etiology/transmission MH - Male MH - Middle Age MH - Rats MH - Russia/epidemiology MH - Seroepidemiologic Methods RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940922 DP - 1993 Jul-Aug IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 62-5 SB - M CY - RUSSIA IP - 4 JC - Y9O AA - Author EM - 9411 AB - During the period of 34 years (1957-1990) diseases caused by leptospires of the serogroup canicola were confirmed in 2.7% of the total number of patients. The analysis revealed that in the presence of epidemic outbreaks Leptospira infection caused by bacteria of the serogroup canicola occurred 1.7 times more often than at the time when such outbreaks were absent. Periodic increases of leptospirosis caused by this serogroup were registered in individual towns and regions of the territory in different years. The analysis of 33 medical histories made it possible to state that the clinical manifestations of leptospirosis caused by bacteria of the serogroup canicola were characteristic of Leptospira infections caused not only by this serovar. As a rule, this kind of leptospirosis was registered in rural and urban areas as individual isolated cases. PMID- 8067118 TT - Zabolevaniia cheloveka, vyzvannye leptospirami serogruppy canicola, v Krasnodarskom krae. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1993 Jul-Aug;(4):62-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 95093898 AU - Avdeeva MG AU - Mel'nik GV AU - Lebedev VV AU - Shubich MG TI - [Prognostic significance of the NBT test in patients with ichterohaemorrhagic leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Aged MH - Comparative Study MH - English Abstract MH - Female MH - Human MH - Male MH - Middle Age MH - Nitroblue Tetrazolium/*diagnostic use MH - Prognosis MH - Weil's Disease/*diagnosis RN - 298-83-9 (Nitroblue Tetrazolium) PT - CLINICAL TRIAL PT - CONTROLLED CLINICAL TRIAL PT - JOURNAL ARTICLE DA - 950123 DP - 1993 Jul-Aug IS - 0869-2084 TA - Klin Lab Diagn PG - 22-5 CY - RUSSIA IP - 4 JC - B17 AA - Author EM - 9503 AB - The values of spontaneous NBT test significantly rise at the peak of leptospirosis in patients with an uncomplicated course of the disease (p < 0.05). Low values of the spontaneous NBT test with stimulation with Staphylococcus in patients with grave leptospirosis predict the development of life-threatening complications. Leptospirosis vaccine reduced the elevated values of the NBT in leptospirosis. The depressing effect of leptospirosis vaccine is indicative of a high risk of development of late complications. PMID- 8000787 TT - Prognosticheskoe znachenie NST-testa u bol'nykh ikterogemorragicheskim leptospirozom. EA - A SO - Klin Lab Diagn 1993 Jul-Aug;(4):22-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 95033145 AU - Nuti M AU - Amaddeo D AU - Caprilli F AU - Crescimbeni E AU - Antoniazzi G AU - Lalli C AU - Prignano G AU - Franco E AU - Cristaldi M TI - [Tiber environment and infections: antibodies to hantaviruses, Leptospira, Borrelia and hepatitis A virus in subjects active on the river banks] LA - Ita MH - Adolescence MH - Adult MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - Borrelia/*immunology MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Hantavirus/*immunology MH - Hantavirus Infections/epidemiology MH - Hepatitis A/epidemiology MH - Hepatitis Antibodies/analysis MH - Hepatovirus/*immunology MH - Human MH - Italy/epidemiology MH - Leptospira/*immunology MH - Leptospirosis/epidemiology MH - Lyme Disease/epidemiology MH - Middle Age MH - Occupations RN - 0 (hepatitis A virus antibodies) RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) RN - 0 (Hepatitis Antibodies) PT - JOURNAL ARTICLE DA - 941128 DP - 1993 Jul-Aug IS - 1120-9135 TA - Ann Ig PG - 259-65 CY - ITALY IP - 4 VI - 5 JC - AND EM - 9502 AD - 1st. di Clinica delle Malattie Tropicali e Infettive, Universita degli Studi di Roma La Sapienza. PMID- 7524553 CU - 95 TT - Ambiente Tevere e infezioni: anticorpi contro hantavirus, Leptospire, Borrelie e virus della epatite A in soggetti a contatto con il fiume. SO - Ann Ig 1993 Jul-Aug;5(4):259-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [92 medline neighbors] UI - 93376681 AU - Duval G AU - van der Linden T AU - Jacob F AU - Michault A AU - Law-Koune JD AU - Campinos L TI - [Human polyvalent immunoglobulins: what is their value in thrombopenia in the course of leptospirosis? (letter)] LA - Fre MH - Adult MH - Female MH - Human MH - *Immunization, Passive MH - Male MH - Thrombocytopenia/etiology/immunology/*therapy MH - Weil's Disease/*complications/immunology PT - LETTER DA - 931007 DP - 1993 Jun 12 IS - 0755-4982 TA - Presse Med PG - 1012 SB - M SB - X CY - FRANCE IP - 21 VI - 22 JC - PMT EM - 9312 PMID- 8367431 TT - Immunoglobulines humaines polyvalentes: quel interet pour la thrombopenie au cours de la leptospirose? SO - Presse Med 1993 Jun 12;22(21):1012 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 93376671 AU - Penalba C AU - Lanoux P AU - Legin C AU - Reksa A AU - Reveil JC TI - [Diagnosis of leptospirosis, contribution of hemoculture. 11 cases (letter)] LA - Fre MH - Female MH - *Hematologic Tests MH - Human MH - Leptospirosis/*blood/diagnosis MH - Male PT - LETTER DA - 931007 DP - 1993 Jun 5 IS - 0755-4982 TA - Presse Med PG - 966 SB - M SB - X CY - FRANCE IP - 20 VI - 22 JC - PMT EM - 9312 PMID- 8367423 TT - Diagnostic de leptospirose, apport de l'hemoculture. 11 observations. SO - Presse Med 1993 Jun 5;22(20):966 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 93286008 AU - Ralph D AU - Que Q AU - Van Etten JL AU - McClelland M TI - Leptospira genomes are modified at 5'-GTAC. LA - Eng MH - Base Sequence MH - Cytosine/analogs & derivatives/metabolism MH - DNA, Bacterial/*genetics MH - Leptospira/*genetics MH - Methylation MH - Restriction Mapping MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. RN - 0 (DNA, Bacterial) RN - 554-01-8 (5-methylcytosine) RN - 71-30-7 (Cytosine) PT - JOURNAL ARTICLE ID - R29AI32644/AI/NIAID ID - 2RO1AI34829/AI/NIAID ID - 1RO1HG00456/HG/NCHGR DA - 930713 DP - 1993 Jun IS - 0021-9193 TA - J Bacteriol PG - 3913-5 SB - M CY - UNITED STATES IP - 12 VI - 175 JC - HH3 AA - Author EM - 9309 AB - Genomic DNAs of 14 strains from seven species of the spirochete Leptospira were resistant to cleavage by the restriction endonuclease RsaI (5'-GTAC). A modified base comigrating with m4C was detected by chromatography. Genomic DNAs from other spirochetes, Borrelia group VS461, and Serpulina strains were not resistant to RsaI digestion. Modification at 5'-GTAm4C may occur in most or all strains of all species of Leptospira but not in all genera of spirochetes. Genus-wide DNA modification has rarely been observed in bacteria. AD - California Institute of Biological Research, La Jolla 92037. PMID- 8509345 SO - J Bacteriol 1993 Jun;175(12):3913-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [84 medline neighbors] UI - 93390675 AU - den Haan PJ AU - van Vliet AC AU - Hazenberg BP TI - Weil's disease as a cause of jaundice. LA - Eng MH - Aged MH - Animal MH - Bilirubin/blood MH - Case Report MH - Diagnosis, Differential MH - *Disease Vectors MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Leisure Activities MH - Leptospira interrogans/classification MH - Liver Function Tests MH - Male MH - Middle Age MH - Occupations MH - Prognosis MH - *Rats MH - Serotyping MH - *Water Microbiology MH - Weil's Disease/*blood/microbiology/physiopathology/transmission RN - 635-65-4 (Bilirubin) PT - JOURNAL ARTICLE DA - 931021 DP - 1993 Jun IS - 0300-2977 TA - Neth J Med PG - 171-4 CY - NETHERLANDS IP - 5-6 VI - 42 JC - NWY AA - Author EM - 9312 AB - Two patients are described with Weil's disease as a rare cause of jaundice. We discuss some features that can lead to early diagnosis. This concerns the apparently aspecific flu-like syndrome that precedes the icteric phase of the disease, as well as the typical pattern of liver function tests in the jaundiced patient: serum bilirubin is markedly elevated as compared with the liver enzymes. Another clue to the diagnosis can be obtained by enquiring not only about the patient's profession, but also about his leisure activities, since both patients acquired the disease in their leisure time. AD - Department of Internal Medicine, Drechtsteden Ziekenhuis Refaja, Dordrecht, Netherlands. PMID- 8377875 SO - Neth J Med 1993 Jun;42(5-6):171-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 93360524 AU - Reid HA AU - Herron AJ AU - Hines ME 2d AU - Orchard EA AU - Altman NH TI - Leptospirosis in a white-lipped tamarin (Saguinus labiatus). LA - Eng MH - Animal MH - Case Report MH - Female MH - Leptospirosis/microbiology/pathology/*veterinary MH - Monkey Diseases/microbiology/*pathology MH - Saguinus/*microbiology PT - JOURNAL ARTICLE DA - 930921 DP - 1993 Jun IS - 0023-6764 TA - Lab Anim Sci PG - 258-9 SB - M CY - UNITED STATES IP - 3 VI - 43 JC - KYS EM - 9311 AD - Division of Comparative Pathology, University of Miami School of Medicine, Florida 33101. PMID- 8355489 SO - Lab Anim Sci 1993 Jun;43(3):258-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 93357531 AU - Cacciapuoti B AU - Ciceroni L AU - Hookey JV TI - Chromosomal rearrangement and serovar conversion in Leptospira biflexa strains. LA - Eng MH - Animal MH - Antigenic Variation/*genetics MH - Antigens, Bacterial/genetics/*immunology MH - Base Sequence MH - Blotting, Southern MH - *Chromosomes, Bacterial/ultrastructure MH - DNA, Bacterial MH - Electrophoresis, Polyacrylamide Gel MH - Immunoblotting MH - Leptospira/classification/*genetics/*immunology MH - Male MH - Molecular Sequence Data MH - Phenotype MH - Rabbits MH - *Recombination, Genetic MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 930921 DP - 1993 Jun IS - 0934-8840 TA - Int J Med Microbiol Virol Parasitol Infect Dis PG - 479-99 SB - M CY - GERMANY IP - 4 VI - 278 JC - BD7 AA - Author EM - 9311 AB - A bacterial population change involving chromosomal rearrangement and phenotypic changes in antigens, proteins and lipopolysaccharides is described for strains of Leptospira biflexa that were previously grown in media containing homologous oligoclonal antibodies. The chromosomal rearrangement phenomenon showed that the variants differed from the parent strains, yet they were similar to phenotypically related serovars already occurring in nature. Accordingly, in vitro serovar conversion mediated by chromosomal rearrangement, due to as yet unknown genetic mechanisms, had occurred. AD - National Center for Leptospirosis, Bacteriology and Medical Mycology Department, Istituto Superiore di Sanita, Rome, Italy. PMID- 8353321 SO - Int J Med Microbiol Virol Parasitol Infect Dis 1993 Jun;278(4):479-99 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [31 medline neighbors] UI - 93355596 AU - Stair EL AU - Edwards WC AU - Burrows GE AU - Torbeck K TI - Suspected red maple (Acer rubrum) toxicosis with abortion in two Percheron mares. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Case Report MH - Female MH - Horse Diseases/*etiology MH - Horses MH - Plant Poisoning/complications/*veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 930914 DP - 1993 Jun IS - 0145-6296 TA - Vet Hum Toxicol PG - 229-30 SB - M CY - UNITED STATES IP - 3 VI - 35 JC - XBV AA - Author EM - 9311 AB - Horses develop severe and often fatal hemolytic anemia after ingesting dried leaves from red maple (Acer rubrum) trees. Toxicosis appears related to an unknown oxidant present in the dried or wilted leaves. This case report describes 2 horses that aborted and developed fatal hemolytic anemia after consuming wilted leaves from red maple (Acer rubrum). While an absolute diagnosis was not confirmed due to lack of proper antemortem and postmortem examinations, red maple toxicosis appeared a reasonable diagnosis based on clinical signs and laboratory findings. Other differentials include equine infectious anemia, autoimmune hemolytic anemia, piroplasmosis, leptospirosis, ehrlichiosis, and other plant or chemical sources of oxidants (onion, garlic, kale, phenothiazines). AD - Oklahoma Animal Disease Diagnostic Laboratory, Oklahoma State University, Stillwater 74078. PMID- 8351795 SO - Vet Hum Toxicol 1993 Jun;35(3):229-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 94063800 AU - Li Y AU - Dai B AU - Zhao H TI - [Antigen analysis of McAb E4B7D5 directed against outer envelope of Leptospira interrogans serovar lai by SDS-PAGE and immunoblot] LA - Chi MH - Animal MH - Antibodies, Monoclonal MH - Antigens, Bacterial/*analysis MH - Bacterial Outer Membrane Proteins/*immunology MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel MH - English Abstract MH - Immunoblotting MH - Leptospira interrogans/classification/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) PT - JOURNAL ARTICLE DA - 931227 DP - 1993 Jun IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 122-6 CY - CHINA IP - 2 VI - 24 JC - GEB AA - Author EM - 9403 AB - McAb E4B7D5 was prepared by hybridoma technology in BALB/c mice immunized to outer envelope of Leptospira interrogans serovar lai. This McAb agglutinated specifically with all the 13 serovars of Icterohaemorrhagiae serogroup in MAT test at high titres and protected the guinea pigs against the attack of virulent strain (017) of serovar lai. SDS-PAGE and immunoblot were used to analyse the reaction of the outer envelopes of the five strains of Leptospira (Leptospira interrogans Icterohaemorrhagiae serogroup, serovar lai, 017 and 601 stains; L. interrogans Hebdomadis serogroup, hebdomadis serovar strain 156; L. interrogans Australis serogroup australis serovar strain 620; biflexa leptospira patoc serovar strain Patoc I; with McAb E4B7D5. Results indicated that this McAb E4B7D5 recognized specifically 34.5 kd and 39.5 kd outer envelope proteins of serovar lai, strain 017 and 601, so it might be an immunoprotective McAb directed against Leptospira interrogans serovar lai. It was suggested that 34.5 kd and 39.5 kd outer envelope proteins of serovar lai recognized specifically by McAb E4B7D5 might be immunoprotective antigens. PMID- 8244286 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1993 Jun;24(2):122-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [22 medline neighbors] UI - 94033899 AU - Rocha T AU - Cardoso EA AU - Terrinha AM AU - Nunes JF AU - Hovind-Hougen K AU - Cinco M TI - Isolation of a new serovar of the genus Leptonema in the family Leptospiraceae. LA - Eng MH - Human MH - HIV Infections/complications/microbiology MH - Leptospiraceae/classification/*isolation & purification/ultrastructure MH - Leptospirosis/complications/microbiology MH - Lymphocytes/microbiology PT - JOURNAL ARTICLE DA - 931201 DP - 1993 Jun IS - 0934-8840 TA - Int J Med Microbiol Virol Parasitol Infect Dis PG - 167-72 SB - M CY - GERMANY IP - 2 VI - 279 JC - BD7 AA - Author EM - 9402 AB - A leptospira-like spirochete was isolated from a lymphocyte culture from a HIV-I and HTLV-I/II-positive patient. On the basis of serological, biological and morphological characteristics of the cells of the isolated strain (strain Lisboa), we conclude that it is a member of the genus Leptonema. AD - Laboratorio Nacional de Investigacao Veterinaria (Dept. Bacteriologia), Lisboa, Portugal. PMID- 8219489 SO - Int J Med Microbiol Virol Parasitol Infect Dis 1993 Jun;279(2):167-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 94030282 AU - Verdugo-Rodriguez A AU - Gam LH AU - Devi S AU - Koh CL AU - Puthucheary SD AU - Calva E AU - Pang T TI - Detection of antibodies against Salmonella typhi outer membrane protein (OMP) preparation in typhoid fever patients. LA - Eng MH - Antibodies, Bacterial/*analysis MH - Bacterial Infections/immunology MH - Bacterial Outer Membrane Proteins/*immunology MH - Comparative Study MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Escherichia coli/immunology MH - False Positive Reactions MH - Human MH - IgG/immunology MH - Immunoblotting MH - Predictive Value of Tests MH - Salmonella typhi/*immunology MH - Sensitivity and Specificity MH - Support, Non-U.S. Gov't MH - Typhoid/diagnosis/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 931216 DP - 1993 Jun IS - 0125-877X TA - Asian Pac J Allergy Immunol PG - 45-52 SB - M CY - THAILAND IP - 1 VI - 11 JC - ABB AA - Author EM - 9402 AB - An indirect ELISA was used to detect antibodies against outer membrane protein preparations (OMPs) from Salmonella typhi. Sera from patients with a definitive diagnosis of typhoid fever (TF) gave a mean absorbance reading, at 414 nm, of 1.52 +/- 0.23 as compared to 0.30 +/- 0.11 for sera from healthy individuals. This gave a positive to negative ratio of absorbance readings of approximately 5.1. Suspected TF patients (no isolation of S. typhi), with positive and negative Widal titers had mean absorbance readings of 1.282 +/00.46 and 0.25 +/- 0.19, respectively. Sera from patients with leptospirosis, rickettsial typhus, dengue fever, and other infections gave mean absorbances of 0.20 +/- 0.08, 0.24 +/- 0.08, 0.27 +/- 0.08, and 0.31 +/- 0.16, respectively. The sensitivity, specificity, positive and negative predictive values were 100%, 94%, 80% and 100%, respectively. The antibody response detected in the definitive TF cases was predominantly IgG in nature and no cross-reactivity was seen with OMP preparations extracted from E. coli. Variable reactivity was noted with OMP preparations obtained from other Salmonella spp. Three major OMPs are presented in the antigen preparation and strong binding of positive sera was detected to all three bands. AD - Institute for Advanced Studies, University of Malaya, Kuala Lumpur. PMID- 8216558 SO - Asian Pac J Allergy Immunol 1993 Jun;11(1):45-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 94003444 AU - Pacciarini ML AU - Savio ML AU - Donini G AU - Tagliabue S TI - The search for improved methods for diagnosing leptospirosis: the approach of a laboratory in Brescia, Italy. LA - Eng MH - Animal MH - *Animals, Domestic MH - Antibodies, Bacterial/blood MH - Antigens, Bacterial/analysis MH - DNA, Bacterial/*analysis MH - Italy MH - Leptospira interrogans/classification/*genetics/immunology/isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - Nucleic Acid Hybridization MH - Polymerase Chain Reaction MH - Polymorphism, Restriction Fragment Length MH - Restriction Mapping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 931026 DP - 1993 Jun IS - 0253-1933 TA - Rev Sci Tech PG - 647-63 SB - M CY - FRANCE IP - 2 VI - 12 JC - A9R AA - Author EM - 9401 AB - The authors describe work in progress at the laboratory in Brescia, Italy, on the application of molecular methods to the diagnosis of leptospirosis. This work includes the following: a) Development of polymerase chain reaction (PCR) assays capable of amplifying specific deoxyribonucleic acid fragments from most Leptospira interrogans strains. b) Development of a microtitre-based assay for rapid detection of PCR-positive samples. c) Characterisation of Leptospira strains through restriction endonuclease analysis of PCR products and amplified fragment length polymorphism. AD - Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia, Brescia, Italy. PMID- 8104548 CU - 94 SO - Rev Sci Tech 1993 Jun;12(2):647-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 93239352 AU - Yuri K AU - Takamoto Y AU - Okada M AU - Hiramune T AU - Kikuchi N AU - Yanagawa R TI - Chemotaxis of leptospires to hemoglobin in relation to virulence. LA - Eng MH - Animal MH - Cattle MH - Chemotaxis MH - *Hemoglobins MH - In Vitro MH - Leptospira/*pathogenicity RN - 0 (Hemoglobins) PT - JOURNAL ARTICLE DA - 930524 DP - 1993 May IS - 0019-9567 TA - Infect Immun PG - 2270-2 SB - M SB - X CY - UNITED STATES IP - 5 VI - 61 JC - GO7 AA - Author EM - 9307 AB - A guinea pig-lethal line of Leptospira interrogans serovar copenhageni strain Shibaura, but not an avirulent line of the same strain, moved in larger numbers toward hemoglobin than toward distilled water (control) in a U-shaped polypropylene tube. L. interrogans serovar lai strains 017 and KH-1, which were also guinea pig lethal, showed a similar move to hemoglobin. No such move toward hemoglobin was shown by 14 avirulent strains of L. interrogans (with one exception) or any of the 8 strains of L. biflexa tested. AD - Department of Epizootiology, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan. PMID- 8478123 SO - Infect Immun 1993 May;61(5):2270-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [4 protein links] [1 nucleotide link] [180 medline neighbors] UI - 93329356 AU - Ding M AU - Yelton DB TI - Cloning and analysis of the leuB gene of Leptospira interrogans serovar pomona. LA - Eng MH - Alcohol Oxidoreductases/analysis/*genetics MH - Alleles MH - Amino Acid Sequence MH - Base Sequence MH - Cloning, Molecular MH - Comparative Study MH - Escherichia coli/genetics MH - Genes, Bacterial/*genetics MH - Genetic Complementation Test MH - Genome, Bacterial MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - Sequence Analysis, DNA MH - Sequence Deletion MH - Sequence Homology, Amino Acid MH - Serotyping MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. RN - EC 1.1 (Alcohol Oxidoreductases) RN - EC 1.1.1.85 (3-isopropylmalate dehydrogenase) PT - JOURNAL ARTICLE ID - DE04645/DE/NIDR ID - 2S07RR05433/RR/NCRR DA - 930820 DP - 1993 May IS - 0022-1287 TA - J Gen Microbiol PG - 1093-103 SB - M CY - ENGLAND VI - 139 ( Pt 5) JC - I87 AA - Author EM - 9310 AB - The leuB gene of Leptospira interrogans serovar pomona strain kenniwicki has been cloned on a 9.5 kb plasmid, pWVL1, by complementation of Escherichia coli leuB mutants. Subcloning and Tn5 mutagenesis showed that the region required for complementation was approximately 1.2 kb in length. Enzyme assays showed that the product of the cloned gene was a beta-isopropylmalate dehydrogenase. Defects in the leuA, leuC and leuD genes of E. coli were not complemented by pWVL1. The nucleotide sequence of the leuB-complementing region and surrounding DNA has been determined. Three open reading frames were found which encode proteins of 40.9, 38.8 and 15 kDa. Analysis of subclones containing nucleotide deletions of varying sizes showed that only the 38.8 kDa protein was necessary to obtain complementation of E. coli leuB mutations. The PIR data base was searched and the enzyme 3- isopropylmalate dehydrogenase from six different micro-organisms was found to share significant amino acid sequence similarity (43-57%) with the 38.8 kDa L. interrogans leuB gene product. The organization of the leucine biosynthetic genes in L. interrogans differs from that found in E. coli, Salmonella typhimurium and Bacillus subtilis. AD - Department of Microbiology and Immunology, West Virginia University, Morgantown 26506-9177. PMID- 8336106 GS - leuB SI - GENBANK/M59431 SO - J Gen Microbiol 1993 May;139 ( Pt 5):1093-103 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [6 protein links] [1 nucleotide link] [143 medline neighbors] UI - 93323752 AU - Ballard SA AU - Segers RP AU - Bleumink-Pluym N AU - Fyfe J AU - Faine S AU - Adler B TI - Molecular analysis of the hsp (groE) operon of Leptospira interrogans serovar copenhageni. LA - Eng MH - Amino Acid Sequence MH - Bacterial Proteins/*genetics MH - Base Sequence MH - Chromosome Mapping MH - Cloning, Molecular MH - Comparative Study MH - Heat MH - Heat-Shock Proteins/*genetics MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - Operon/*genetics MH - Repetitive Sequences, Nucleic Acid/genetics MH - RNA, Messenger/genetics MH - Sequence Analysis, DNA MH - Sequence Homology, Amino Acid MH - Serotyping MH - Support, Non-U.S. Gov't MH - Transcription, Genetic RN - 0 (Bacterial Proteins) RN - 0 (GroEL Protein) RN - 0 (Heat-Shock Proteins) RN - 0 (RNA, Messenger) PT - JOURNAL ARTICLE DA - 930816 DP - 1993 May IS - 0950-382X TA - Mol Microbiol PG - 739-51 SB - M CY - ENGLAND IP - 4 VI - 8 JC - MOM AA - Author EM - 9310 AB - A chromosomal gene library of Leptospira interrogans serovar copenhageni strain Wijnberg was constructed in phage lambda gt11. Plaque immunoassay with R alpha P64 antiserum identified one clone expressing a putative groEL homologue. DNA sequence analysis of the 2.4 kb EcoRI-Bam HI cloned fragment from strain Wijnberg revealed two open reading frames encoding polypeptides of 10.5 kDa (Hsp10) and 58 kDa (Hsp58). Sequence comparison of the deduced amino acid sequences of these ORFs confirmed the operon as the groE equivalent of Leptospira. Transcriptional analysis suggested that this operon is primarily under the control of an E sigma 70 promoter element. However, both Hsp10 and Hsp58 were overexpressed under heat-shock conditions as determined by [35S]-methionine pulse labelling experiments. As no functional heat- shock promoter could be identified, a 9bp inverted repeat, located between the transcription and translation start sites, may play a role in the upregulation of this operon under heat-shock conditions, similar to mechanisms described for several Gram-positive organisms. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 8101351 CU - 94 SI - GENBANK/L14682 SO - Mol Microbiol 1993 May;8(4):739-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 93266440 AU - Bernard WV AU - Bolin C AU - Riddle T AU - Durando M AU - Smith BJ AU - Tramontin RR TI - Leptospiral abortion and leptospiruria in horses from the same farm. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Antibodies, Bacterial/blood MH - Bacteriuria/microbiology/*veterinary MH - Case Report MH - Female MH - Horse Diseases/*microbiology MH - Horses MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Pregnancy RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930621 DP - 1993 Apr 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1285-6 SB - M CY - UNITED STATES IP - 8 VI - 202 JC - HAV AA - Author EM - 9308 AB - Leptospirosis was documented as the cause of abortion in a 5-year-old mare. Leptospires were detected in tissue specimens from fetal kidneys and from placenta by histologic evaluation of silver-stained sections. Antibodies against Leptospira interrogans serovar pomona were detected in fetal serum at a titer of 1,600 by use of a microscopic agglutination test. The mare had serum titers of 6,400; 0; 400; 800; 3,200; and 6,400 to L interrogans serovars bratislava, canicola, grippotyphosa, hardjo, icterohaemorrhagiae, and pomona, respectively. A serologic survey identified titers of at least 6,400 against serovars bratislava and pomona in 5 other horses on the farm. Titers of at least 100 against serovar bratislava were detected in 53% of the horses on the farm. Leptospires were detected by direct fluorescent-antibody testing in urine samples from the mare that aborted and from 2 of the other 5 horses. AD - Rood and Riddle Equine Hospital, Lexington, KY 40580. PMID- 8496088 SO - J Am Vet Med Assoc 1993 Apr 15;202(8):1285-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 93294543 AU - Livesley MA AU - Thompson IP AU - Bailey MJ AU - Nuttall PA TI - Comparison of the fatty acid profiles of Borrelia, Serpulina and Leptospira species. LA - Eng MH - Borrelia/*chemistry/classification MH - Chromatography, Gas MH - Comparative Study MH - Fatty Acids/*analysis/chemistry MH - Leptospira/*chemistry/classification MH - Serpulina/*chemistry/classification MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Fatty Acids) PT - JOURNAL ARTICLE DA - 930722 DP - 1993 Apr IS - 0022-1287 TA - J Gen Microbiol PG - 889-95 SB - M CY - ENGLAND VI - 139 ( Pt 4) JC - I87 AA - Author EM - 9309 AB - Fatty acid methyl ester (FAME) derivatives were examined as a means of characterizing Borrelia burgdorferi isolates and distinguishing them from other spirochaetes. Analysis was performed using a gas liquid chromatography column in conjunction with Microbial Identification System (MIS) software. Reproducible FAME profiles were produced which distinguished Borrelia species, Serpulina hyodysenteriae and Leptospira icterohaemorrhagiae. Furthermore, the FAME profiles of four recognized Borrelia species (including two American isolates of Borrelia burgdorferi, B31 and JD1) were distinct from one another and from the BSK II medium in which they were grown. The results confirm previous reports that FAME profiles of bacteria represent a diagnostic phenotypic property and suggest that they may have applications in the chemotaxonomic classification of Borrelia species. AD - NERC Institute of Virology and Environmental Microbiology, Oxford, UK. PMID- 8515244 SO - J Gen Microbiol 1993 Apr;139 ( Pt 4):889-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 93263671 AU - Takashima I AU - Ngoma M AU - Hashimoto N TI - Antimicrobial effects of a new carboxyquinolone drug, Q-35, on five serogroups of Leptospira interrogans. LA - Eng MH - Anti-Infective Agents, Quinolone/*pharmacology MH - Kinetics MH - Leptospira interrogans/*drug effects/growth & development MH - Microbial Sensitivity Tests MH - Nephelometry and Turbidimetry MH - Quinolones/*pharmacology RN - 0 (Anti-Infective Agents, Quinolone) RN - 0 (Quinolones) RN - 127294-70-6 (balofloxacin) PT - JOURNAL ARTICLE DA - 930611 DP - 1993 Apr IS - 0066-4804 TA - Antimicrob Agents Chemother PG - 901-2 SB - M CY - UNITED STATES IP - 4 VI - 37 JC - 6HK AA - Author EM - 9308 AB - New carboxyquinolone drugs, including the recently developed Q-35, were evaluated for their in vitro potency against five serogroups of Leptospira interrogans. Q-35, ofloxacin, ciprofloxacin, and tosufloxacin showed MICs (0.05 to 0.20 microgram/ml) comparable to those of tetracycline. However, MBCs of these drugs varied between 10- and 100-fold above the MIC for most strains tested. Q-35 was shown to be active against L. interrogans in vitro as judged by the MICs obtained. AD - Department of Veterinary Public Health, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. PMID- 8388204 CU - 96 SO - Antimicrob Agents Chemother 1993 Apr;37(4):901-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 94102839 AU - Venkataraman KS AU - Nedunchelliyan S TI - A report on the isolation of Leptospira icterohaemorrhagiae serovar from man. LA - Eng MH - Case Report MH - Culture Media MH - Human MH - Leptospira interrogans/*isolation & purification MH - Male MH - Middle Age MH - Urine/microbiology MH - Weil's Disease/*microbiology/urine RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 940207 DP - 1993 Apr IS - 0377-4929 TA - Indian J Pathol Microbiol PG - 168-9 CY - INDIA IP - 2 VI - 36 JC - GKK EM - 9404 AD - Department of Preventive Medicine, Veterinary College and Research Institute, Namakkal, Tamil Nadu. PMID- 8276483 SO - Indian J Pathol Microbiol 1993 Apr;36(2):168-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [73 medline neighbors] UI - 94269473 AU - de Vasconcelos LM AU - Ramos-Vieira M das N AU - Osorio-Cisalpino E AU - Cota-Koury M TI - [Survey of anti-Leptospira agglutinins in workers from the city of Londrina-Parana, Brazil] LA - Por MH - Abattoirs MH - Adolescence MH - Adult MH - Agglutinins/*blood MH - Agricultural Workers' Diseases/epidemiology/microbiology MH - Animal Husbandry MH - Antibodies, Bacterial/*blood MH - Brazil/epidemiology MH - Child MH - Child, Preschool MH - Comparative Study MH - English Abstract MH - Female MH - Food Handling MH - Housekeeping MH - Human MH - Leptospira/classification/*immunology MH - Leptospirosis/*epidemiology/immunology/microbiology MH - Male MH - Middle Age MH - Occupational Diseases/epidemiology/microbiology MH - *Occupations MH - Seroepidemiologic Methods MH - Students MH - Urban Population RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940714 DP - 1993 Apr-Jun IS - 0187-4640 TA - Rev Latinoam Microbiol PG - 153-7 CY - MEXICO IP - 2 VI - 35 JC - SEP AA - Author EM - 9409 AB - Serum samples were obtained from 249 individuals in Londrina-Parana, Brazil. The sera were analysed for leptospiral agglutinins by microscopic agglutination tests and 22.1% were positive. Of these positives per group were 24.6% for butchers, 25.9% for farm workers, 17.2% for children and 22.2% for servants. The agglutinin titers ranged from 1:200 to 1:3200. The highest titers were obtained for the serovars sejroe (butchers), grippotyphosa (farm workers), javanica, canicola, panama, wolffi and pyrogenes (children) and butembo (servants). AD - Departamento de Microbiologia, Universidade Federal de Minas Gerais, Brasil. PMID- 8209108 TT - Pesquisa de aglutininas anti Leptospira en trabalhadores da cidade de Londrina-Parana, Brasil. EA - A SO - Rev Latinoam Microbiol 1993 Apr-Jun;35(2):153-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 93242717 AU - Woodward MJ AU - Redstone JS TI - Differentiation of leptospira serovars by the polymerase chain reaction and restriction fragment length polymorphism. LA - Eng MH - Animal MH - Base Sequence MH - DNA, Bacterial/*analysis MH - DNA, Single-Stranded/chemistry MH - Leptospira/*classification/genetics MH - Molecular Sequence Data MH - *Polymerase Chain Reaction MH - *Polymorphism, Restriction Fragment Length RN - 0 (DNA, Bacterial) RN - 0 (DNA, Single-Stranded) PT - JOURNAL ARTICLE DA - 930525 DP - 1993 Mar 27 IS - 0042-4900 TA - Vet Rec PG - 325-6 SB - M CY - ENGLAND IP - 13 VI - 132 JC - XBS EM - 9307 AD - Molecular Genetics Unit, Central Veterinary Laboratory, Addlestone, Surrey. PMID- 8097604 CU - 94 SO - Vet Rec 1993 Mar 27;132(13):325-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 93270329 AU - Wells SJ AU - Trent AM AU - Robinson RA AU - Knutson KS AU - Bey RF TI - Association between clinical lameness and Borrelia burgdorferi antibody in dairy cows. LA - Eng MH - Animal MH - Antibodies, Bacterial/*blood MH - Borrelia burgdorferi/*immunology MH - Cattle MH - Cattle Diseases/*physiopathology MH - Enzyme-Linked Immunosorbent Assay MH - *Gait MH - Human MH - Lactation MH - Leptospira/immunology MH - Lyme Disease/physiopathology/*veterinary MH - Movement Disorders/physiopathology/*veterinary MH - Seasons MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930618 DP - 1993 Mar IS - 0002-9645 TA - Am J Vet Res PG - 398-405 SB - M CY - UNITED STATES IP - 3 VI - 54 JC - 40C AA - Author EM - 9308 AB - Results of an ELISA, indirect fluorescent antibody (IFA) test, and immunoblot analysis (western blotting) for antibody to Borrelia burgdorferi in a sample of 216 lactating dairy cows were compared. The microscopic microtitration agglutination test for antibody to 6 serovars of Leptospira interrogans was also performed to evaluate possible cross-reactivity between B burgdorferi and L interrogans. Using western blotting as the standard test against which the ELISA and IFA test were compared, the ELISA had greater sensitivity (50% in summer and 38% in spring) with similar specificity (83 and 82%), compared with the IFA test (sensitivity, 6 and 5%; specificity, 90 and 83%). In addition, seropositivity to B burgdorferi, using the ELISA, was not found to be associated with seropositivity to L interrogans serovars. A matched case-control study evaluating the association between clinical lameness and antibody to B burgdorferi was performed in lactating dairy cows of 17 Minnesota and Wisconsin herds. Sera from case and control cows matched by herd, parity, and stage of lactation were evaluated, using an ELISA for B burgdorferi antibody during 2 seasons. High B burgdorferi antibody values were associated with clinical lameness in dairy cows (P = 0.006 in summer and P = 0.04 in spring). AD - Department of Clinical Science, College of Veterinary Medicine, University of Minnesota, St Paul 55108. PMID- 8498742 SO - Am J Vet Res 1993 Mar;54(3):398-405 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 93267562 AU - Myburgh JG AU - Posnett SJ AU - Lawrence JV TI - Serological survey for canine leptospirosis in the Pretoria area. LA - Eng MH - Animal MH - Antibodies, Bacterial/*blood MH - Dog Diseases/*epidemiology MH - Dogs MH - Hemagglutination Tests MH - Leptospira interrogans/*isolation & purification MH - South Africa/epidemiology MH - Weil's Disease/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930622 DP - 1993 Mar IS - 0301-0732 TA - J S Afr Vet Assoc PG - 37-8 SB - M CY - SOUTH AFRICA IP - 1 VI - 64 JC - JZH AA - Author EM - 9308 AB - Canine serum samples (n = 400) from the Pretoria area were tested for Leptospira antibodies, using the microscopic agglutination test. The prevalence of antibodies (inconclusive and positive titres) was 1.5%. Reactions were only against Leptospira interrogans serovars tarassovi and pyrogens. Leptospirosis does not appear to be an important canine disease in the Pretoria area. AD - Reproduction Section, Veterinary Research Institute, Onderstepoort, Republic of South Africa. PMID- 8496894 SO - J S Afr Vet Assoc 1993 Mar;64(1):37-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [168 medline neighbors] UI - 93236512 AU - Djordjevic S AU - Hornitzky M AU - Ross AD AU - Whittington RJ TI - Restriction-endonuclease analysis of Australian isolates of Leptospira interrogans serovar hardjo from cattle with agalactia and abortion. LA - Eng MH - Abortion, Veterinary/*diagnosis MH - Animal MH - Bacterial Typing Techniques/veterinary MH - Cattle MH - Cattle Diseases/*microbiology MH - DNA, Bacterial/analysis MH - Female MH - Lactation Disorders/microbiology/*veterinary MH - Leptospira interrogans/classification/genetics/*isolation & purification MH - Polymerase Chain Reaction/*veterinary MH - Pregnancy MH - Urine/microbiology MH - Weil's Disease/microbiology/*veterinary RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 930520 DP - 1993 Mar IS - 0005-0423 TA - Aust Vet J PG - 98-100 SB - M CY - AUSTRALIA IP - 3 VI - 70 JC - 9IE AA - Author EM - 9307 AB - Polyacrylamide gel electrophoresis and agarose gel electrophoresis were used to resolve restriction endonuclease digests of 20 Australian Isolates of Leptospira interrogans cultured from urine samples of cattle with agalactia and abortion. The restriction endonuclease profiles of 19 isolates closely matched the profiles of L interrogans serovar hardjo subtype hardjobovis reference strains. The remaining isolate had a different restriction profile from subtype hardjobovis and subtype hardjoprajitno reference strains and was serologically identified as serovar pomona. Silver staining of polyacrylamide gels gave enhanced resolution of restriction fragments compared with the traditional method of ethidium bromide staining of agarose gels. AD - New South Wales Agriculture, Elizabeth Macarthur Agricultural Institute, Camden, New South Wales. PMID- 8476365 SO - Aust Vet J 1993 Mar;70(3):98-100 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 93210079 AU - Zuerner RL AU - Ellis WA AU - Bolin CA AU - Montgomery JM TI - Restriction fragment length polymorphisms distinguish Leptospira borgpetersenii serovar hardjo type hardjo-bovis isolates from different geographical locations. LA - Eng MH - Americas/epidemiology MH - Animal MH - Blotting, Southern MH - Cattle MH - Cattle Diseases/epidemiology/*microbiology MH - Comparative Study MH - Deoxyribonucleases, Type II Site-Specific/metabolism MH - DNA Insertion Elements/genetics MH - DNA, Bacterial/genetics/metabolism MH - Europe/epidemiology MH - Genome, Bacterial MH - Human MH - Leptospira/*classification/genetics MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Middle East/epidemiology MH - New Zealand/epidemiology MH - Nucleic Acid Hybridization MH - Plasmids/genetics MH - *Polymorphism, Restriction Fragment Length MH - Restriction Mapping MH - Swine RN - EC 3.1.21.4 (Deoxyribonucleases, Type II Site-Specific) RN - 0 (DNA Insertion Elements) RN - 0 (DNA, Bacterial) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 930427 DP - 1993 Mar IS - 0095-1137 TA - J Clin Microbiol PG - 578-83 SB - M CY - UNITED STATES IP - 3 VI - 31 JC - HSH AA - Author EM - 9307 AB - Genetic variability among Leptospira borgpetersenii serovar hardjo type hardjo-bovis isolates representing several geographical regions was determined by restriction endonuclease analysis. Five previously unidentified EcoRI digestion patterns and one previously unidentified HhaI digestion pattern were seen with the various isolates. The copy number and genomic distribution of an L. borgpetersenii insertion sequence (IS1533) was determined. Hardjo-bovis isolate 033 (the type strain for hardjo-bovis) contained 40 well dispersed copies of IS1533. IS1533 probes were used to compare hardjo-bovis isolates by DNA blot hybridization analysis. Use of these probes showed the presence of additional genetic heterogeneity among hardjo-bovis isolates, which restriction endonuclease analysis did not show. Pulsed-field gel electrophoretic analysis of DNAs from several isolates suggested that some polymorphisms arose by genomic rearrangements. All hardjo-bovis isolates were categorized into 14 distinct groups on the basis of common hybridization and endonuclease digestion patterns. Most of these groups were isolated from distinct geographical regions, suggesting that several different clonal populations of hardjo-bovis exist. AD - Leptospirosis and Mycobacteriosis Research Unit, National Animal Disease Center, Ames, Iowa 50010. PMID- 7681437 CU - 95 SO - J Clin Microbiol 1993 Mar;31(3):578-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 94035497 AU - Ferguson IR TI - Leptospirosis surveillance: 1990-1992. LA - Eng MH - England/epidemiology MH - Human MH - Leptospirosis/diagnosis/*epidemiology/therapy MH - Wales/epidemiology PT - JOURNAL ARTICLE DA - 931220 DP - 1993 Feb 26 IS - 1350-9349 TA - Commun Dis Rep CDR Rev PG - R47-8 CY - ENGLAND IP - 3 VI - 3 JC - BUR AA - Author EM - 9402 AB - Leptospirosis remains a potential hazard to farmers, agricultural workers and those coming into contact with rats or natural inland waters. The annual reported incidence in England and Wales ranged between 29 and 48 cases during 1990-92. AD - Hereford Public Health Laboratory. PMID- 7693148 CU - 95 SO - Commun Dis Rep CDR Rev 1993 Feb 26;3(3):R47-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 93261977 AU - Morillon M AU - Perolat P AU - Morlat C TI - [Double Listeria monocytogenes and Leptospira infection (letter)] LA - Fre MH - Adolescence MH - Ampicillin/therapeutic use MH - Case Report MH - Human MH - Leptospirosis/*complications/drug therapy MH - Listeria monocytogenes/*isolation & purification MH - Male MH - Meningitis, Listeria/*complications/drug therapy/microbiology RN - 69-53-4 (Ampicillin) PT - LETTER DA - 930615 DP - 1993 Feb 6 IS - 0755-4982 TA - Presse Med PG - 176 SB - M SB - X CY - FRANCE IP - 4 VI - 22 JC - PMT EM - 9308 PMID- 8493235 TT - Double infection a Listeria monocytogenes et Leptospira. SO - Presse Med 1993 Feb 6;22(4):176 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 93278733 AU - Lin J TI - [The type of leptospirosis epidemic and serogroup transformation in Fujian province in recent years] LA - Chi MH - Animal MH - Cattle MH - China/epidemiology MH - English Abstract MH - Human MH - Leptospira/*classification MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*epidemiology/microbiology/veterinary MH - Muridae/*microbiology MH - Serotyping MH - Weil's Disease/*epidemiology/microbiology/veterinary PT - JOURNAL ARTICLE DA - 930707 DP - 1993 Feb IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 26-9 CY - CHINA IP - 1 VI - 14 JC - CQG AA - Author EM - 9309 AB - By analysis of investigations in recent years in Fujian province, it was found that the main type of leptospirosis epidemic was rice-field type, the other was flood type which had the tendency to shift from coastal plain area to northwest area. In the main epidemic area, Wupin county, the detection rate of Hebdomadis serogroup rate sharply declined (P < 0.01), however, that of Batavia serogroup markedly increased (P < 0.01). AD - Fujian Provincial Hygiene and Epidemic Prevention Station, Fuzhou. PMID- 8504450 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1993 Feb;14(1):26-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 93213953 AU - Sugiyama Y AU - Sugiyama F AU - Yagami K TI - Comparative study on cross-reaction of leptospiral antibodies in several serological tests to detect antibodies to Borrelia burgdorferi in dogs. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*blood MH - Borrelia burgdorferi/*immunology MH - Comparative Study MH - Cross Reactions MH - Dogs/*immunology MH - Enzyme-Linked Immunosorbent Assay/methods/veterinary MH - Fluorescent Antibody Technique/veterinary MH - Leptospira/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930505 DP - 1993 Feb IS - 0916-7250 TA - J Vet Med Sci PG - 149-51 SB - M CY - JAPAN IP - 1 VI - 55 JC - A27 AA - Author EM - 9307 AB - The effects by the leptospiral antibody are described at several serological tests for the detection of the antibody to B. burgdorferi in dogs. The titers at ELISA used with the ultrasonicated bacterial antigen (US-ELISA) were related with IFA. But cross reaction with the leptospiral antibody were shown in an agglutination test. Non-specific and cross-reactions were observed in ELISA used with formalin-killed bacterial antigen. This indicates that US-ELISA is a reliable serodiagnosis method for Lyme disease in dogs in eliminating the cross reaction with leptospiral antibody. AD - Laboratory Animal Research Center, University of Tsukuba, Ibaraki, Japan. PMID- 8461411 SO - J Vet Med Sci 1993 Feb;55(1):149-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [87 medline neighbors] UI - 93186413 TI - OSHA's bloodborne pathogens standard: analysis and recommendations. LA - Eng MH - Blood/microbiology MH - Hazardous Substances MH - Health Personnel/*legislation & jurisprudence/standards MH - Hepatitis B/immunology/*prevention & control/transmission MH - Human MH - HIV Infections/immunology/*prevention & control/transmission MH - Infection Control/*legislation & jurisprudence MH - Inservice Training/legislation & jurisprudence MH - Occupational Exposure/*legislation & jurisprudence MH - United States MH - United States Occupational Safety and Health Administration MH - Vaccination MH - Virus Diseases/immunology/prevention & control/transmission RN - 0 (Hazardous Substances) PT - JOURNAL ARTICLE DA - 930402 DP - 1993 Feb IS - 0046-7022 TA - Health Devices PG - 35-92 SB - M CY - UNITED STATES IP - 2 VI - 22 JC - G24 AA - Author EM - 9306 AB - Just over a year ago, the Occupational Safety and Health Administration (OSHA) issued the final bloodborne pathogens standard, "Occupational Exposure to Bloodborne Pathogens; Final Rule," which requires healthcare institutions to protect their employees from all occupational exposure to bloodborne pathogens." According to OSHA, the only criterion for applying the standard is the likelihood of exposure to blood and other potentially infectious materials (OPIMs). Thus, the standard is designed to protect all vulnerable personnel, from the clinical engineers who service contaminated equipment to the staff in clinical laboratories, patient care or treatment areas, and housekeeping and laundry services--any location where the nature of the work poses the risk of exposure to bloodborne pathogens. All department heads and employees must have access to the standard and should carefully review our analysis of the regulations and recommendations for implementing them, as presented in this special issue of Health Devices. The standard is aimed at protecting employees from occupational exposure to all bloodborne pathogens and, especially, to the human immunodeficiency virus (HIV) and the hepatitis B virus (HBV)-- the most infamous pathogens transmitted through occupational exposure to blood and body fluids. Other bloodborne diseases referenced by OSHA in the preamble to the standard include arboviral infections, babesiosis, brucellosis, Creutzfeldt-Jakob disease, hepatitis C, human T-lymphotropic virus type I, leptospirosis, malaria, relapsing fever, syphilis, and viral hemorrhagic fever. In this issue, we provide a clinical overview of HIV and HBV and the diseases they cause, as well as a brief discussion of other bloodborne pathogens; an analysis of the most significant regulations affecting hospitals; and our recommendations for compliance. The recommendations presented in this article do not exhaust the possibilities for reducing exposure and complying with the standard. We invite you to communicate your ideas and practices regarding compliance issues to the ECRI-sponsored Center for Healthcare Environmental Management (CHEM) for possible inclusion in a future update to its loose-leaf reference publication, the Healthcare Environmental Management System. We wish to acknowledge CHEM's contribution in developing this special report, which was reviewed by the Centers for Disease Control and Prevention (CDC), the National Institute for Occupational Safety and Health (NIOSH), and OSHA. Also see "CDC's Recommendations for Hepatitis B Vaccination and Postexposure Follow-up" and "A Minimal Training Syllabus" in this issue. PMID- 8444629 NI - A SO - Health Devices 1993 Feb;22(2):35-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [39 medline neighbors] UI - 93156074 AU - Ratnam S AU - Everard CO AU - Alex JC AU - Suresh B AU - Thangaraju P TI - Prevalence of leptospiral agglutinins among conservancy workers in Madras City, India. LA - Eng MH - Adult MH - Age Factors MH - Agglutination Tests MH - Agglutinins/*blood MH - Female MH - Human MH - India/epidemiology MH - Leptospira interrogans/classification/*immunology MH - Male MH - Middle Age MH - Occupational Diseases/*epidemiology MH - Poverty Areas MH - Prevalence MH - *Sanitary Engineering MH - Serotyping MH - Sex Factors MH - Support, Non-U.S. Gov't MH - Weil's Disease/*epidemiology RN - 0 (Agglutinins) PT - JOURNAL ARTICLE DA - 930310 DP - 1993 Feb IS - 0022-5304 TA - J Trop Med Hyg PG - 41-5 SB - M CY - ENGLAND IP - 1 VI - 96 JC - KAV AA - Author EM - 9305 AB - In a study of 584 Corporation conservancy (sanitation) workers who lived mostly in slums, and who worked in four Corporation Circles of Madras City, India, 192 (32.9%) were found to be positive for agglutinins to Leptospira interrogans. Seropositivity prevalence increased with age, but was similar in males and females except in the youngest age group, where males predominated. Prevalence in the four study areas ranged between 17.8 and 40.5% (P < 0.01). Among 152 sera in which one serogroup predominated, Autumnalis was the most commonly recorded (33.6%), followed by Icterohaemorrhagiae (15.1%), Panama (15.1%), Sejroe (14.5%) and others (21.7%). Forty sera reacted to two or more serogroups at the same (highest) titre, most frequently to the first three serogroups above. The titre range was 1:50-1:3200 (geometric mean titre 149). Among a group of 46 male automobile industry workers who lived in middle-class housing, seropositivity prevalence (17.4%) was approximately half that of the sanitation workers (P < 0.05), and the titre range was lower (1:50-1:200, GMT 84). The predominating serogroups were those found in the sanitation workers. Bearing in mind that sanitation workers are the urban group probably at highest risk of leptospiral infection, the prevalence rate (< 33%) found in our study is not considered to be particularly high. AD - Tamilnadu Veterinary and Animal Sciences University, Madras, India. PMID- 8429573 SO - J Trop Med Hyg 1993 Feb;96(1):41-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 93138809 AU - Shaffer JM AU - Baker-Zander SA AU - Lukehart SA TI - Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes. LA - Eng MH - Animal MH - Antibodies, Bacterial/*immunology MH - IgG/*immunology MH - Immune Sera/immunology MH - *Phagocytosis MH - Rabbits MH - Support, U.S. Gov't, P.H.S. MH - Treponema pallidum/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (IgG) RN - 0 (Immune Sera) PT - JOURNAL ARTICLE ID - AI 18988/AI/NIAID DA - 930222 DP - 1993 Feb IS - 0019-9567 TA - Infect Immun PG - 781-4 SB - M SB - X CY - UNITED STATES IP - 2 VI - 61 JC - GO7 AA - Author EM - 9304 AB - Rabbit antisera to Leptospira interrogans, Borrelia hermsii, and Treponema phagedenis biotype Reiter, reactive to shared spirochetal antigens, failed to enhance phagocytosis of Treponema pallidum by macrophages, while immunoglobulin G to Treponema pallidum subsp. pertenue and Treponema paraluiscuniculi promoted phagocytosis. Opsonic antibodies are directed to pathogen-restricted, not shared spirochetal, antigens. AD - Department of Medicine, University of Washington, Seattle 98195. PMID- 8423106 SO - Infect Immun 1993 Feb;61(2):781-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 93163062 AU - Ralph D AU - McClelland M AU - Welsh J AU - Baranton G AU - Perolat P TI - Leptospira species categorized by arbitrarily primed polymerase chain reaction (PCR) and by mapped restriction polymorphisms in PCR-amplified rRNA genes. LA - Eng MH - Base Sequence MH - Comparative Study MH - DNA, Bacterial/genetics MH - DNA, Ribosomal/*genetics MH - Genes, Structural, Bacterial MH - Leptospira/classification/*genetics MH - Molecular Sequence Data MH - Oligodeoxyribonucleotides/chemistry MH - Phylogeny MH - Polymerase Chain Reaction MH - Polymorphism, Restriction Fragment Length MH - RNA, Ribosomal/genetics MH - Sequence Alignment MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. RN - 0 (DNA, Bacterial) RN - 0 (DNA, Ribosomal) RN - 0 (Oligodeoxyribonucleotides) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE ID - HG00106/HG/NCHGR ID - AI32644/AI/NIAID DA - 930315 DP - 1993 Feb IS - 0021-9193 TA - J Bacteriol PG - 973-81 SB - M CY - UNITED STATES IP - 4 VI - 175 JC - HH3 AA - Author EM - 9305 AB - Reference strains from 48 selected serovars representing eight species of Leptospira were examined by two polymerase chain reaction (PCR)- based strategies. First, mapped restriction site polymorphisms (MRSP) were examined in PCR products from portions of rrs (16S rRNA gene) and rrl (23S rRNA gene). Twenty MRSP and 2 length polymorphisms were used to group reference strains into 16 MRSP profiles. Species assignments were consistent with those obtained by a second method, genomic fingerprinting with arbitrarily primed PCR, in which strains within a species were characterized by many shared arbitrarily primed PCR products. The results of both of these methods were in general agreement with those of previous studies that used DNA-DNA relatedness and confirmed the high level of divergence among the recognized species of Leptospira. However, Leptospira meyeri serovar ranarum and evansi strains were indistinguishable from some strains of Leptospira interrogans sensu stricto. Intervening sequences of about 485 to 740 bp were located near base 1230 in rrl of some strains. AD - California Institute of Biological Research, La Jolla 92037. PMID- 8094390 CU - 94 GS - rrs GS - rrl SI - GENBANK/X17547 SI - GENBANK/X14249 SO - J Bacteriol 1993 Feb;175(4):973-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 93158159 AU - Bennett RM TI - Decision support models of leptospirosis in dairy herds. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*economics/epidemiology MH - Costs and Cost Analysis MH - Dairying/*economics MH - *Decision Support Techniques MH - Female MH - Leptospirosis/economics/epidemiology/*veterinary MH - Risk Factors PT - JOURNAL ARTICLE DA - 930309 DP - 1993 Jan 16 IS - 0042-4900 TA - Vet Rec PG - 59-61 SB - M CY - ENGLAND IP - 3 VI - 132 JC - XBS AA - Author EM - 9305 AB - Following the results of a survey which found that 61 per cent of dairy farmers felt that they needed more information about leptospirosis, and the strategies for its control and the costs and benefits involved, this paper describes the construction and preliminary results of two models of the disease intended to help explore the risks and financial implications of Leptospira interrogans serovar hardjo infection for dairy producers. AD - Department of Agricultural Economics and Management, University of Reading. PMID- 8430482 SO - Vet Rec 1993 Jan 16;132(3):59-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 93108996 AU - Hindrichsen S AU - Medeiros de Andrade A AU - Clement J AU - Leirs H AU - McKenna P AU - Matthys P AU - Neild GH TI - Hantavirus infection in Brazilian patients from Recife with suspected leptospirosis [letter] LA - Eng MH - Antibodies, Viral/*analysis MH - Brazil MH - Diagnosis, Differential MH - Hantavirus/*immunology MH - Hemorrhagic Fever with Renal Syndrome/*diagnosis MH - Human MH - Leptospirosis/*diagnosis MH - Serodiagnosis RN - 0 (Antibodies, Viral) PT - LETTER DA - 930127 DP - 1993 Jan 2 IS - 0140-6736 TA - Lancet PG - 50 SB - A SB - M SB - X CY - ENGLAND IP - 8836 VI - 341 JC - L0S EM - 9303 PMID- 8093292 CU - 94 SO - Lancet 1993 Jan 2;341(8836):50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 97271807 AU - Duca E AU - Barhala M AU - Florescu R AU - Trifan M AU - Fochi M AU - Bunea C TI - [The evolution of leptospirosis in Iasi County in 1988-1992] LA - Rum MH - Adult MH - Age Distribution MH - Female MH - Human MH - Incidence MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Risk Factors MH - Romania/epidemiology MH - Rural Population/statistics & numerical data MH - Sex Distribution MH - Urban Population/statistics & numerical data MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 970430 DP - 1993 Jan-Jun TA - Bacteriol Virusol Parazitol Epidemiol PG - 39-43 CY - ROMANIA IP - 1-2 VI - 38 JC - BFP EM - 9707 AD - Inspectoratul Judetean de Politie Sanitara si Medicina Preventiva, Iasi. PMID- 9132110 NP - X TT - Evolutia leptospirozei in judetul Iasi in perioada 1988-1992. SO - Bacteriol Virusol Parazitol Epidemiol 1993 Jan-Jun;38(1-2):39-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [50 medline neighbors] UI - 93255789 AU - Treml F AU - Nesnalova E TI - [Occurrence of Leptospira antibodies in the blood of game animals] LA - Cze MH - Animal MH - Animals, Wild/immunology/*microbiology MH - Antibodies, Bacterial/*analysis MH - English Abstract MH - Leptospira/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930609 DP - 1993 IS - 0375-8427 TA - Vet Med (Praha) PG - 123-7 CY - CZECHOSLOVAKIA IP - 2 VI - 38 JC - XBP AA - Author EM - 9308 AB - The blood serum of game was examined for the presence of antibodies to Leptospiras in 1987-1989. A total of 792 blood sera from animals belonging to 14 zoo-species were examined (Tab. I). The blood serum of red deer (Cervus elephus) was examined the most often within the group of animals, in 398 cases, i.e. 50.2%, followed by 165 blood sera of wild boar (Sus scrofa), representing 20.8%, and by 136 blood sera of roedeer (Capreolus capreolus), representing 18.6%. Small numbers of blood sera of the other animals were examined. A serological reaction of microagglutination-lysion revealed the antibodies to Leptospiras in fifty examined samples, i.e. 6.31%, of the six examined zoo-species: muskrat (Ondatra zibethica) 14.28%, wild boar (Sus scrofa) 13.93%, roedeer (Capreolus capreolus) 6.76%, fox (Vulpes vulpes) 5.26%, red deer (Cervus elephus) 3.76%, mouflon (Ovis musimon) 2.50%. No antibodies to Leptospiras were found in the blood serum of the other animal species (Tab. I). Twelve strains of Leptospira were used for serological examination according to the standard method (Sebek, 1979). The examined blood sera of game reacted only with Leptospiras of the serotype L. grippotyphosa. No reaction with other Leptospira serotypes was observed. Our results have demonstrated, in comparison with the results of foreign authors, great susceptibility of the game to infection with different serotypes of Leptospira. But it is possible to say that with certain exceptions these game species do not play an important role in the epidemiology of Leptospirosis. AD - Vysoka skola veterinarni a farmaceuticka, Brno. PMID- 8488630 TT - Vyskyt protilatek proti Leptospiram v krevnich serech lovne zvere. EA - A SO - Vet Med (Praha) 1993;38(2):123-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 93231288 AU - Cacciapuoti B AU - Ciceroni L AU - Arimitsu Y AU - Sato T AU - Seki M TI - Evaluation of a passive microcapsule agglutination test for the screening of human leptospirosis. LA - Eng MH - Agglutination Tests/*methods MH - Antibodies, Bacterial/blood MH - Capsules MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Italy MH - Leptospirosis/*diagnosis MH - Predictive Value of Tests MH - Reproducibility of Results RN - 0 (Antibodies, Bacterial) RN - 0 (Capsules) PT - JOURNAL ARTICLE DA - 930519 DP - 1993 Jan IS - 0392-2990 TA - Eur J Epidemiol PG - 92-6 SB - M CY - ITALY IP - 1 VI - 9 JC - ERE AA - Author EM - 9307 AB - Microcapsules, absorbed with two mixed antigens--each composed of 3 sonicated leptospira serovars--were developed in the past as a microcapsule agglutination test (MCA-LS) for the screening of clinical leptospirosis. For this study, fifty serum samples, taken at an earlier and at a later stage of illness from 25 Italian in-patients with clinical symptoms of leptospirosis, were tested with both the MCA-LS one-dilution test and the microscopic agglutination (MA) test, the confirmatory test for leptospirosis, with 18 leptospira strains circulating in Italy. Compared with MA, MCA-LS showed a sensitivity of 91.7%, and a specificity of 92.3%, including leptospirosis not sustained by the diagnostic strains used in the MCA-LS kit. AD - National Center for Leptospirosis, Istituto Superiore di Sanita, Rome, Italy. PMID- 8472806 SO - Eur J Epidemiol 1993 Jan;9(1):92-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 93222339 AU - Kirkbride CA TI - Bacterial agents detected in a 10-year study of bovine abortions and stillbirths. LA - Eng MH - *Abortion, Veterinary MH - Actinomyces/isolation & purification MH - Animal MH - Bacillus/isolation & purification MH - Bacteria/*isolation & purification MH - Bacterial Infections/*veterinary MH - Cattle MH - Cattle Diseases/*microbiology MH - Escherichia coli/isolation & purification MH - Female MH - Fetal Death/*veterinary MH - Leptospira interrogans/isolation & purification MH - Listeria/isolation & purification MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/*veterinary MH - Retrospective Studies MH - South Dakota PT - JOURNAL ARTICLE DA - 930510 DP - 1993 Jan IS - 1040-6387 TA - J Vet Diagn Invest PG - 64-8 SB - M CY - UNITED STATES IP - 1 VI - 5 JC - A2D AA - Author EM - 9307 AB - In a 10-year survey started in 1980, specimens from 8,995 bovine abortions and stillbirths were submitted to the South Dakota Animal Disease Research and Diagnostic Laboratory. Of these, 8,962 were suitable for some type of examination. Bacteria were determined to be the cause of 1,299 (14.49%). The 5 bacteria most commonly associated with bovine abortion or stillbirth were Actinomyces pyogenes, 378 (4.22%); Bacillus spp., 321 (3.58%); Listeria spp., 121 (1.35%); Escherichia coli, 98 (1.09%); and Leptospira interrogans, 79 (0.88%). Twelve other genera of bacteria were associated with > or = 10 abortions or stillbirths, and 12 more species were associated with < or = 10 abortions or stillbirths. AD - Veterinary Science Department, South Dakota State University, Brookings 57006. PMID- 8466983 SO - J Vet Diagn Invest 1993 Jan;5(1):64-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [19 medline neighbors] UI - 93222338 AU - Hong CB AU - Donahue JM AU - Giles RC Jr AU - Petrites-Murphy MB AU - Poonacha KB AU - Roberts AW AU - Smith BJ AU - Tramontin RR AU - Tuttle PA AU - Swerczek TW TI - Etiology and pathology of equine placentitis. LA - Eng MH - Abortion, Veterinary MH - Allantois/microbiology/pathology MH - Animal MH - Bacteria/isolation & purification MH - Bacterial Infections/pathology/*veterinary MH - Chorion/microbiology/pathology MH - Female MH - Fetal Death/veterinary MH - Horse Diseases/*etiology/*pathology MH - Horses MH - Inflammation MH - Placenta/microbiology/*pathology MH - Placenta Diseases/etiology/pathology/*veterinary MH - Pregnancy MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 930510 DP - 1993 Jan IS - 1040-6387 TA - J Vet Diagn Invest PG - 56-63 SB - M CY - UNITED STATES IP - 1 VI - 5 JC - A2D AA - Author EM - 9307 AB - Placentas from aborted, stillborn, and premature foals were examined during the 1988 and 1989 foaling seasons, and 236 of 954 (24.7%) had placentitis. Microorganisms associated with placentitis were isolated or demonstrated from 162 of 236 (68.6%) placentitis cases. Leptospira spp. and a nocardioform actinomycete were 2 important, newly emerging bacteria associated with equine placentitis. Major pathogens identified in decreasing order were Streptococcus zooepidemicus, Leptospira spp., Escherichia coli, a nocardioform actinomycete, fungi, Pseudomonas aeruginosa, Streptococcus equisimilis, Enterobacter agglomerans, Klebsiella pneumoniae, and alpha-hemolytic Streptococcus. Pathogens were not recovered in 64 cases (27.1%) and overgrowth by saprophytic bacteria was recorded in 10 cases (4.2%). Twenty-seven cases (16.6%) had mixed bacterial growth and 93 cases (57.4%) had bacteria cultured from both placenta and fetal organs. The majority of the placentitis cases caused by bacteria, with the exception of Leptospira spp. and the nocardioform actinomycete, occurred in 2 forms. One was acute, focal or diffuse; had an infiltration of neutrophils in the intervillous spaces or necrosis of chorionic villi; was associated with bacteremia; and frequently occurred in the placenta from fetuses expelled before or at midgestation. The other was observed from foals expelled at late gestation, was mostly chronic and focal or focally extensive, and occurred mostly at the cervical star area. Chronic placentitis was characterized by the presence of 1 or a combination of the following lesions: necrosis of chorionic villi, presence of eosinophilic amorphous material on the chorion, and infiltration of mononuclear inflammatory cells in the intervillous spaces, villous stroma, chorionic stroma, vascular layer, and allantois.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Livestock Disease Diagnostic Center, University of Kentucky, Lexington 40511. PMID- 8466982 SO - J Vet Diagn Invest 1993 Jan;5(1):56-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 93152457 AU - Feresu SB AU - Bolin CA AU - Korver H TI - A new leptospiral serovar in the Icterohaemorrhagiae serogroup isolated from an ox in Zimbabwe. LA - Eng MH - Animal MH - Cattle/*microbiology MH - Leptospira interrogans/*classification/*isolation & purification MH - Serotyping MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Zimbabwe PT - JOURNAL ARTICLE ID - 1 F05 TW4154-01/TW/FIC DA - 930309 DP - 1993 Jan IS - 0020-7713 TA - Int J Syst Bacteriol PG - 179-82 SB - M CY - UNITED STATES IP - 1 VI - 43 JC - AWO AA - Author EM - 9305 AB - A strain of Leptospira interrogans that was isolated from an ox slaughtered in Zimbabwe and belonged to serogroup Icterohaemorrhagiae could not be identified when we compared it with 18 reference strains belonging to this serogroup by using cross-agglutinin absorption, monoclonal antibody, and restriction endonuclease DNA analyses. The name zimbabwe is proposed for the new serovar containing this strain; the type strain of this serovar is strain SBF 23. AD - Department of Biological Sciences, University of Zimbabwe, Mount Pleasant, Harare. PMID- 8427806 SO - Int J Syst Bacteriol 1993 Jan;43(1):179-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 93151375 AU - Sasaki DM AU - Pang L AU - Minette HP AU - Wakida CK AU - Fujimoto WJ AU - Manea SJ AU - Kunioka R AU - Middleton CR TI - Active surveillance and risk factors for leptospirosis in Hawaii. LA - Eng MH - Adult MH - Aged MH - Case-Control Studies MH - Double-Blind Method MH - Female MH - Follow-Up Studies MH - Hawaii/epidemiology MH - Human MH - Incidence MH - Interviews MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Rain MH - Retrospective Studies MH - Risk Factors MH - Sex Factors MH - Support, Non-U.S. Gov't MH - Water Supply PT - JOURNAL ARTICLE DA - 930302 DP - 1993 Jan IS - 0002-9637 TA - Am J Trop Med Hyg PG - 35-43 SB - A SB - M CY - UNITED STATES IP - 1 VI - 48 JC - 3ZQ AA - Author EM - 9305 AB - A clinic-hospital-based leptospirosis surveillance program was conducted to determine the morbidity and risk factors in nonepidemic settings. The study was conducted on two islands, Kauai and Hawaii (Big Island), in the state of Hawaii for one year during 1988 and 1989. An active, more comprehensive case detection system was used on the Big Island that enabled us to determine the incidence of clinical disease. Subjects from both islands were used to conduct a case-control study for risk factors. One hundred seventy-two subjects from the Big Island (who presented with any two of the following symptoms: fever, headache, myalgia, or nausea/vomiting) were enrolled in the study. Twenty cases were diagnosed by culture, serology, or fluorescent antibody tissue staining at autopsy. Six cases required hospitalization and two succumbed to fatal infections. We estimated that these cases represented an annual incidence rate of 128 per 100,000 person-years in our target population. For 33 cases, 77 controls were matched for island, age, sex, and time of onset of illness. Interviews were conducted retrospectively in a double-blinded fashion with cases and controls and evaluated approximately 30 risk factors. Factors that were associated most strongly with development of leptospirosis were household use of rainwater catchment systems (P = 0.003), presence of skin cuts during the incubation period (P = 0.008), contact with cattle or the urine of cattle (P = 0.05 and P = 0.03, respectively), and handling of animal tissues (P = 0.005).(ABSTRACT TRUNCATED AT 250 WORDS) AD - Hawaii State Department of Health, Honolulu. PMID- 8427386 SO - Am J Trop Med Hyg 1993 Jan;48(1):35-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 93145601 AU - Sayahtaheri-Altaie S AU - Meier FA AU - Dalton HP TI - Identification of species-specific, non-cross-reactive proteins of Borrelia burgdorferi. LA - Eng MH - Antibodies, Anti-Idiotypic/immunology MH - Arthritis, Rheumatoid/blood MH - Bacterial Proteins/*analysis/immunology/metabolism MH - Borrelia burgdorferi/*immunology/isolation & purification MH - Comparative Study MH - Cross Reactions/immunology MH - Diagnosis, Differential MH - Escherichia coli/immunology MH - Human MH - IgG/immunology MH - IgM/immunology MH - Infectious Mononucleosis/blood MH - Leptospira interrogans/immunology MH - Lupus Erythematosus, Systemic/blood MH - Lyme Disease/blood/diagnosis/*microbiology MH - Species Specificity MH - Treponema/classification/immunology RN - 0 (Antibodies, Anti-Idiotypic) RN - 0 (Bacterial Proteins) RN - 0 (IgG) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 930304 DP - 1993 Jan IS - 0732-8893 TA - Diagn Microbiol Infect Dis PG - 43-51 SB - M CY - UNITED STATES IP - 1 VI - 16 JC - DMI AA - Author EM - 9305 AB - The low specificity of diagnostic tests for Lyme disease is due to the fact that Borrelia burgdorferi possesses many antigenic proteins that are cross-reactive with other spirochetes and bacteria. The low sensitivity is a result of high (> or = 1:100) dilutions used for patient sera during testing to eliminate non-specific cross-reactivity. The present study was conducted to identify species-specific non-cross- reactive protein(s) of B. burgdorferi that might be used as antigen(s) in serologic tests. Whole-cell sonicates of B. burgdorferi were tested against pooled sera from patients with symptoms, signs, and serologic features diagnostic of Lyme disease (LD), rheumatoid arthritis, infectious mononucleosis, systemic lupus erythematosus, Rocky Mountain spotted fever, secondary syphilis, and from healthy individuals. Different LD pools were also tested against whole-cell sonicates of Treponema pallidum, Treponema phagedenis, Leptospira interrogans, and Escherichia coli. Comparison among patterns obtained by each serum pool revealed that IgM antibodies to species-specific 39-, 23-, and 22-kD proteins and IgG antibodies to 34- and 31-kD proteins were present only in the patients with LD and absent from patients with rheumatoid arthritis, infectious mononucleosis, systemic lupus erythematosus, Rocky Mountain spotted fever, secondary syphilis, and healthy individuals pools. These results suggest that 39-, 23-, and 22-kD proteins may be used in an IgM immunoassay for diagnosis of LD. AD - Department of Pediatrics (S.S.A.), State University of New York, Buffalo School of Medicine. PMID- 8425377 SO - Diagn Microbiol Infect Dis 1993 Jan;16(1):43-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 93132269 AU - Monno S AU - Mizushima Y TI - Leptospirosis with acute acalculous cholecystitis and pancreatitis. LA - Eng MH - Acute Disease MH - Aged MH - Case Report MH - Cholecystitis/*etiology MH - Diagnosis, Differential MH - Human MH - Leptospirosis/*complications/*diagnosis/microbiology MH - Male MH - Pancreatitis/*etiology PT - JOURNAL ARTICLE DA - 930212 DP - 1993 Jan IS - 0192-0790 TA - J Clin Gastroenterol PG - 52-4 SB - M CY - UNITED STATES IP - 1 VI - 16 JC - IBG AA - Author EM - 9304 AB - Severe Leptospira autumnalis infection was associated with acute acalculous cholecystitis and pancreatitis in a 66-year-old man. He was successfully treated with antimicrobial agents and supportive therapy, including hemodialysis. We review these uncommon manifestations and the effectiveness of antimicrobial therapy in advanced leptospirosis. AD - First Department of Internal Medicine, School of Medicine, Toyama Medical and Pharmaceutical University, Japan. PMID- 8421147 SO - J Clin Gastroenterol 1993 Jan;16(1):52-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [82 medline neighbors] UI - 93109793 AU - Jackson LA AU - Kaufmann AF AU - Adams WG AU - Phelps MB AU - Andreasen C AU - Langkop CW AU - Francis BJ AU - Wenger JD TI - Outbreak of leptospirosis associated with swimming. LA - Eng MH - Adolescence MH - Animal MH - Animals, Domestic/microbiology MH - Animals, Wild/microbiology MH - Cohort Studies MH - *Disease Outbreaks MH - *Disease Reservoirs MH - Human MH - Illinois/epidemiology MH - Leptospira interrogans/*isolation & purification MH - Male MH - Swimming MH - *Water Microbiology MH - Weil's Disease/diagnosis/*epidemiology PT - JOURNAL ARTICLE DA - 930127 DP - 1993 Jan IS - 0891-3668 TA - Pediatr Infect Dis J PG - 48-54 SB - M CY - UNITED STATES IP - 1 VI - 12 JC - OXJ AA - Author EM - 9303 AB - Between July 7 and 18, 1991, five boys from a small town in rural Illinois experienced the onset of an acute febrile illness subsequently confirmed as leptospirosis by serologic tests. A cohort study found that swimming in a small swimming hole, Steel Tunnel Pond, was associated with disease (P < 0.01), the attack rate being 28%. Leptospira interrogans serovar grippotyphosa was isolated from urine cultures from two of the case patients and from a culture of Steel Tunnel Pond water. A high seroprevalence for grippotyphosa was found in animals near the pond. Drought conditions had been present in the month before the outbreak, creating an environment in the pond which probably facilitated transmission of the organism from area animals to humans. Although leptospirosis is infrequently reported in humans in the United States, it is endemic in animals and the potential for outbreaks exists, especially when environmental conditions are favorable. AD - Meningitis and Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA. PMID- 8417426 SO - Pediatr Infect Dis J 1993 Jan;12(1):48-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 94019982 AU - Abdulkader R AU - Sabbaga E AU - Meireles L AU - Radu A TI - Vascular injury in acute renal failure due to leptospirosis is not associated with antineutrophil cytoplasmic antibody [letter] LA - Eng MH - Adolescence MH - Adult MH - Autoantibodies/blood MH - Female MH - Human MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications MH - Male MH - Vasculitis/*etiology/immunology RN - 0 (Antibodies, Antineutrophil Cytoplasmic) RN - 0 (Autoantibodies) PT - LETTER DA - 931118 DP - 1993 IS - 0028-2766 TA - Nephron PG - 156 SB - M CY - SWITZERLAND IP - 1 VI - 65 JC - NW8 EM - 9401 PMID- 8413778 CU - 96 SO - Nephron 1993;65(1):156 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 94016035 AU - Lacey EJ TI - Leptospirosis. LA - Eng MH - Adult MH - Case Report MH - *Disease Outbreaks MH - Female MH - Great Britain MH - Hong Kong/epidemiology MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Military Personnel PT - JOURNAL ARTICLE DA - 931119 DP - 1993 Spring IS - 0035-9033 TA - J R Nav Med Serv PG - 37-8 CY - ENGLAND IP - 1 VI - 79 JC - JVL EM - 9401 AD - RNH Haslar. PMID- 8410768 SO - J R Nav Med Serv 1993 Spring;79(1):37-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 93392060 AU - Antonov VS AU - Stoianova NA AU - Semenovich VN AU - Rusal'chuk VV AU - Komarova DV TI - [The clinico-epidemiological characteristics of leptospirosis] LA - Rus MH - Acute Disease MH - Adult MH - English Abstract MH - Female MH - Human MH - *Leptospira canicola MH - Leptospirosis/complications/*epidemiology/mortality MH - Male MH - Middle Age MH - Russia/epidemiology MH - Urban Population/statistics & numerical data MH - Weil's Disease/complications/*epidemiology/mortality PT - JOURNAL ARTICLE DA - 931019 DP - 1993 IS - 0040-3660 TA - Ter Arkh PG - 79-81 SB - M CY - RUSSIA IP - 6 VI - 65 JC - VLU EM - 9312 PMID- 8378856 TT - Kliniko-epidemiologicheskaia kharakteristika leptospiroza. EA - A SO - Ter Arkh 1993;65(6):79-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 93392047 AU - Alekseev VG AU - Tsvigun GV AU - Zaikina NA TI - [The ultrasonic diagnosis of the changes in the kidneys in renal forms of acute kidney failure] LA - Rus MH - Acute Disease MH - Diagnosis, Differential MH - English Abstract MH - Ethylene Glycols/poisoning MH - Human MH - Kidney/*ultrasonography MH - Kidney Failure, Acute/etiology/*ultrasonography MH - Leptospirosis/complications/ultrasonography MH - Poisoning/complications/ultrasonography RN - 0 (Ethylene Glycols) RN - 107-21-1 (ethylene glycol) PT - JOURNAL ARTICLE DA - 931019 DP - 1993 IS - 0040-3660 TA - Ter Arkh PG - 35-6 SB - M CY - RUSSIA IP - 6 VI - 65 JC - VLU AA - Author EM - 9312 AB - An ultrasonic investigation of the kidneys in patients with renal forms of acute renal failure (32 and 24 with ethylene glycol poisoning and leptospirosis, respectively) recorded in the oligo-anuric phase a specific ultrasonic picture of renal lesion demonstrable as long as full recovery of impaired functions. The picture was characterized by enlargement of the kidneys with good differentiation of the pyramids in enhanced parenchymal echogenicity. Ethylene glycol poisoning is characterized by limited renal mobility and an echo negative halo around them. These signs may appear helpful in the diagnosis of renal forms of acute renal failure. PMID- 8378845 TT - Ul'trazvukovaia diagnostika izmenenii v pochkakh pri renal'nykh formakh ostroi pochechnoi nedostatochnosti. EA - A SO - Ter Arkh 1993;65(6):35-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 93309659 AU - Manfro RC AU - Boger MV AU - Kopstein J AU - Goncalves LF AU - Prompt CA TI - Acute renal failure due to leptospirosis in a renal transplant patient [letter] LA - Eng MH - Adult MH - Case Report MH - Human MH - Kidney Failure, Acute/*etiology MH - Kidney Transplantation/*adverse effects MH - Leptospirosis/*complications MH - Male MH - Time Factors PT - LETTER DA - 930730 DP - 1993 IS - 0028-2766 TA - Nephron PG - 317 SB - M CY - SWITZERLAND IP - 2 VI - 64 JC - NW8 EM - 9310 PMID- 8321369 SO - Nephron 1993;64(2):317 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 94112807 AU - Akhtar S AU - Riemann HP AU - Thurmond MC AU - Franti CE TI - The association between antibody titres against Campylobacter fetus and milk production efficiency in dairy cattle. LA - Eng MH - Animal MH - Antibodies, Bacterial/*blood MH - Campylobacter fetus/*immunology MH - Campylobacter Infections/physiopathology/*veterinary MH - Cattle MH - Cross-Sectional Studies MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Female MH - Haemophilus/immunology MH - Lactation/*physiology MH - Leptospira/immunology MH - Mastitis, Bovine/*physiopathology MH - Multivariate Analysis MH - Regression Analysis MH - Software MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940217 DP - 1993 IS - 0165-7380 TA - Vet Res Commun PG - 183-91 SB - M CY - NETHERLANDS IP - 3 VI - 17 JC - XCD AA - Author EM - 9404 AB - The association between serological evidence of exposure to Campylobacter fetus and milk production performance was studied in 178 lactating cows from three California Dairy Herd Improvement Association herds using a cross-sectional study design in December 1986. ELISAs were used to determine the antibody titres against Campylobacter fetus, Haemophilus somnus and Leptospira hardjo, which were classified as either negative or positive. The status of a cow as negative or positive against C. fetus and H. somnus represents the serological evidence of natural exposure to the corresponding bacteria. However, the status against L. hardjo was assumed to be the level of vaccinal titre against this organism since all the cows studied had been vaccinated against this agent. The data on demographic and productivity variables relating to the current lactation of the cows were obtained from Dairy Herd Improvement Association individual cow records for December 1986. Four measures of milk production efficiency for the current lactation were used. The status against L. hardjo and other covariates suggested by previous studies were included in modelling the relationships of interest. Stepwise multiple linear regression was used to study the adjusted relationship of C. fetus with each measure of milk production efficiency. Multivariate analyses revealed that the adjusted relationships of C. fetus with the test-day's milk production, the extended 305-day milk production and the relative value of milk production were not significant (p > 0.1). However, after adjusting for possible covariates, C. fetus-positive cows had an average of 7.43% lower mature equivalent milk production than C. fetus-negative cows (p = 0.02).(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Epidemiology and Preventive Medicine, School of Veterinary Medicine, University of California, Davis 95616. PMID- 8284894 SO - Vet Res Commun 1993;17(3):183-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 94067898 AU - Giudicelli J AU - Lemaitre D AU - Fournier V AU - Contamin B AU - Hartemann E AU - Floret D TI - [3 pediatric cases of leptospirosis] LA - Fre MH - Adolescence MH - Age Factors MH - Case Report MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*diagnosis MH - Male PT - JOURNAL ARTICLE DA - 940103 DP - 1993 IS - 0031-4021 TA - Pediatrie PG - 455-8 SB - M CY - FRANCE IP - 6 VI - 48 JC - OY8 AA - Author EM - 9403 AB - Three children presented with an association of pains, infectious syndrome, acute renal failure, hepatitis and meningitis, that lead to the diagnosis of leptospirosis. The clinical spectrum of this rare disease are recalled. AD - Service d'urgence et de reanimation pediatrique, hopital Debrousse, Lyon, France. PMID- 8247645 TT - Trois observations pediatriques de leptospirose. EA - A SO - Pediatrie 1993;48(6):455-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [86 medline neighbors] UI - 94054883 AU - Treml F AU - Nesnalova E TI - [Serologic screening for the occurrence of Leptospira antibodies in small wild mammals] LA - Cze MH - Animal MH - Animals, Wild/microbiology MH - Antibodies, Bacterial/*analysis MH - English Abstract MH - Insectivora/*microbiology MH - Leptospira/*immunology MH - Rodentia/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 931201 DP - 1993 IS - 0375-8427 TA - Vet Med (Praha) PG - 559-68 CY - CZECH REPUBLIC IP - 9 VI - 38 JC - XBP AA - Author EM - 9402 AB - During the five years (1986-1990) free living small mammals were examined serologically for the presence of antibodies to leptospires. Standardized techniques were used in the serological examinations (Sebek, 1979). A total 4634 specimens representing 15 mammalian species were examined. During the studied period, higher occurrence of small terrestrial mammals was noticed in the years 1987-1988. In these years, 61% of specimens out of the total number of trapped animals were examined. The field mice (Apodemus sylvaticus and Apodemus flavicollis) and the common vole (Microtus arvalis) were most frequently examined species, their proportion in the total number being 35.4% and 28.4% respectively. Antibodies to leptospires were demonstrated in 557 cases, i.e. in 12.06%, in specimens representing 10 mammalian species, the higher percentage was recorded only in the year 1988, when antibodies were detected in 15.4%. In 550 cases, i.e. 98.7%, the antibodies were to leptospires of the serovar grippotyphosa and only in 7 cases, i.e. 1.3% to leptospires of the serological group Sejroe. Antibodies to leptospires of the serovar grippotyphosa were found in specimens captured in all localities studied. Antibodies were most frequently detected in the specimens of the common vole (Microtus arvalis) in 6.1% and in both species of field mice (Apodemus sylvaticus and Apodemus flavicollis) in 3.4% of the total number of animals examined. Antibodies to leptospires of the serological group Sejroe were found only in blood sera of the house mouse (Mus musculus) and only in one locality studied. Our results confirmed some previously known facts concerning the distribution and structure of leptospirosis foci on this territory. The study of population dynamics should not be neglected because it is directly proportional to the infestation of individual species as we have evidenced. This fact is most expressive in main reservoir species. AD - Vysoka skola veterinarni a farmaceuticka, Brno. PMID- 8236637 TT - Serologicka depistaz vyskytu protilatek proti leptospiram u volne zijicich drobnych savcu. EA - A SO - Vet Med (Praha) 1993;38(9):559-68 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 94025533 AU - Akhtar S AU - Riemann HP AU - Thurmond MC AU - Franti CE TI - The association between antibody titres against Campylobacter fetus and reproductive efficiency in dairy cattle. LA - Eng MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Campylobacter fetus/*immunology MH - Campylobacter Infections/immunology/physiopathology/*veterinary MH - Cattle MH - Cattle Diseases/*immunology/physiopathology MH - Cross-Sectional Studies MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Fertility/*immunology MH - Haemophilus/immunology MH - Leptospira/immunology MH - Multivariate Analysis MH - Regression Analysis MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 931118 DP - 1993 IS - 0165-7380 TA - Vet Res Commun PG - 95-107 SB - M CY - NETHERLANDS IP - 2 VI - 17 JC - XCD AA - Author EM - 9401 AB - The relationship between the antibody titres against Campylobacter fetus and various indices of reproductive efficiency was studied in a cross-sectional study of 178 dairy cows from three California Dairy Herd Improvement Association herds. Blood samples were collected from the lactating cows during December 1986. Enzyme-linked immunosorbent assays were used to determine the antibody titres of the cow against Campylobacter fetus, Haemophilus somnus and Leptospira hardjo and were classified as either negative or positive. The status of a cow as either negative or positive against Campylobacter fetus and Haemophilus somnus represents serological evidence of natural exposure to the corresponding bacterial agents. However, the status against Leptospira hardjo was assumed to reflect a vaccinal titre since all the cows studied had been routinely vaccinated against this organism in September 1986. The data on demographic and reproductive parameters pertained only to the current lactation of the cows and were obtained from Dairy Herd Improvement Association individual cow records of December 1986. Five indices of reproductive efficiency were used, namely the recent calving interval, the calving-to-conception interval, the calving-to-last-service interval, the number of services per conception, and the number of services since last calving. The serological status against Haemophilus somnus, Leptospira hardjo and other covariates suggested by the results of previous studies were included in modelling the relationships of interest. Stepwise multiple linear regression analyses were carried out to study the adjusted relationship of Campylobacter fetus with each measure of reproductive efficiency. Multivariate analyses revealed that the adjusted relationship for Campylobacter fetus with all five measures of reproductive efficiency was non-significant (p > 0.05). Among the covariates, Leptospira hardjo had a strong and independent relationship with recent calving interval, the unstandardized partial regression coefficient being -0.77. The possible biological mechanisms of these associations are discussed. AD - Department of Epidemiology and Preventive Medicine, School of Veterinary Medicine, University of California, Davis 95616. PMID- 8212528 SO - Vet Res Commun 1993;17(2):95-107 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [210 medline neighbors] UI - 94248549 AU - Dell'isola B AU - Gaillot O AU - Amouriaux P AU - Baranton G AU - Saint Girons I AU - Simonet M AU - Valcke JC TI - [Biological diagnosis of leptospirosis by PCR (polymerase chain reaction) (letter)] LA - Fre MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - *Polymerase Chain Reaction PT - LETTER DA - 940621 DP - 1993 IS - 0248-8663 TA - Rev Med Interne PG - 805-6 SB - M CY - FRANCE IP - 8 VI - 14 JC - SGJ EM - 9408 PMID- 8191096 TT - Diagnostic biologique de la leptospirose par PCR (polymerase chain reaction). SO - Rev Med Interne 1993;14(8):805-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 94227290 AU - Andreescu N TI - Value, possibilities and limitations of the specific serological diagnosis in relation to the evolution of ocular complications in human leptospiroses. LA - Eng MH - Adolescence MH - Adult MH - Antibodies, Bacterial/blood MH - Child MH - Child, Preschool MH - Eye Infections, Bacterial/*diagnosis/etiology MH - Female MH - Human MH - Infant MH - Leptospira/immunology MH - *Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/complications/*diagnosis MH - Male MH - Middle Age MH - Serodiagnosis MH - Weil's Disease/complications/*diagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940608 DP - 1993 Jan-Mar IS - 1220-8485 TA - Roum Arch Microbiol Immunol PG - 15-24 CY - ROMANIA IP - 1 VI - 52 JC - BAQ EM - 9408 AD - Cantacuzino Institute, Bucharest, Romania. RO - M:MWS PMID- 8173121 LR - 960715 SO - Roum Arch Microbiol Immunol 1993 Jan-Mar;52(1):15-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 94194467 AU - Colenbrander B AU - Feitsma H AU - Grooten HJ TI - Optimizing semen production for artificial insemination in swine. LA - Eng MH - Animal MH - Fertility/physiology MH - Insemination, Artificial/*veterinary MH - Male MH - Quality Control MH - *Semen MH - *Spermatozoa MH - Swine/*physiology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, ACADEMIC DA - 940429 DP - 1993 IS - 0449-3087 TA - J Reprod Fertil Suppl PG - 207-15 SB - M CY - ENGLAND VI - 48 JC - JWR AA - Author EM - 9407 AB - Efficient production of high quality semen is of major importance to artificial insemination (AI) organizations. The semen produced should be free of contagious organisms, be of high quality, have good storage properties, fertilizing capacity and be of high genetic value. The best approach to prevent the spreading of microorganisms via semen in the process of AI is to collect semen from boars free from specific diseases, for example pseudorabies virus or leptospirosis. Antibiotics are added to the semen to suppress proliferation of microorganisms or even reduce their number. Sperm production is influenced by many factors such as season, collection frequency, breed and age. The average number of sperm cells produced per boar per week can vary more than 30% within one AI station, depending on the breed. Boar selection and boar management markedly influence the efficiency of sperm production. Sperm quality should be evaluated by fertility results obtained at breeding farms related to both farrowing rate and litter size to ensure a good quality monitoring system. A quality control system should be established to provide maximum reliability to customers. AD - Cooperative Pig AI-Centre, Vught, The Netherlands. RF - 33 PMID- 8145205 SO - J Reprod Fertil Suppl 1993;48:207-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 93317999 AU - Perolat P AU - Lecuyer I AU - Postic D AU - Baranton G TI - Diversity of ribosomal DNA fingerprints of Leptospira serovars provides a database for subtyping and species assignation. LA - Eng MH - DNA Fingerprinting/methods MH - DNA, Ribosomal/*analysis MH - Electrophoresis, Polyacrylamide Gel MH - In Vitro MH - Leptospira/*classification/genetics MH - Polymorphism, Restriction Fragment Length MH - RNA, Ribosomal/*analysis MH - Support, Non-U.S. Gov't RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE DA - 930809 DP - 1993 Jan IS - 0923-2508 TA - Res Microbiol PG - 5-15 SB - M CY - FRANCE IP - 1 VI - 144 JC - R6F AA - Author EM - 9310 AB - Ribosomal DNA fingerprints from 103 pathogenic Leptospira strains were examined using EcoRI restriction and fragment length polymorphisms of rRNA genes. Sixty-nine new leptospiral ribotypes were described, in addition to 49 previously observed. Except for 5 strains, a good correlation between DNA homology data and ribotyping was observed. The genospecies of 31 reference strains could be presumed, since they shared 13 ribotypes with strain(s) previously studied by DNA homology. Furthermore, the definition of common rRNA hybridization fragments in each recognized DNA hybridization group provides information about the status of Leptospira reference strains yet to be classified. With 118 ribotypes now defined among the validated serovar reference strains, rRNA fingerprints constitute a database for subtyping Leptospira species. AD - Laboratoire des Leptospires, Institut Pasteur, Noumea. PMID- 8101010 CU - 94 SO - Res Microbiol 1993 Jan;144(1):5-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 93151373 AU - Nuti M AU - Amaddeo D AU - Crovatto M AU - Ghionni A AU - Polato D AU - Lillini E AU - Pitzus E AU - Santini GF TI - Infections in an Alpine environment: antibodies to hantaviruses, leptospira, rickettsiae, and Borrelia burgdorferi in defined Italian populations. LA - Eng MH - Adult MH - Age Factors MH - Agricultural Workers' Diseases/epidemiology MH - Antibodies, Bacterial/blood MH - Antibodies, Viral/blood MH - Borrelia burgdorferi/immunology MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique MH - Forestry MH - Hantavirus/immunology MH - Hemorrhagic Fever with Renal Syndrome/*epidemiology MH - Human MH - Italy/epidemiology MH - Leptospira/immunology MH - Leptospirosis/*epidemiology MH - Lyme Disease/*epidemiology MH - Military Personnel MH - Occupational Diseases/*epidemiology MH - Prevalence MH - Rickettsiaceae/immunology MH - Rickettsiaceae Infections/*epidemiology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 930302 DP - 1993 Jan IS - 0002-9637 TA - Am J Trop Med Hyg PG - 20-5 SB - A SB - M CY - UNITED STATES IP - 1 VI - 48 JC - 3ZQ AA - Author EM - 9305 AB - From 1987 to 1991, a seroepidemiologic survey for antibodies to hantaviruses, leptospira, rickettsiae, and Borrelia was conducted in selected Italian population groups. In the mountainous areas of northeastern Italy, the prevalence of antibody to hantaviruses, as detected by indirect immunofluorescent antibody (IFA) assay, was 7.1%, 4.8%, 4.3%, and 4% in 265 forestry workers, 82 rangers, 395 farmers, and 75 hunters, respectively. Among 299 Alpine soldiers, the prevalence was lower (0.7%). Of those with Hantaan antibody, the reactivity pattern using Hantaan, Puumala, and Fojnica viruses suggested a prevalence of antibody to Hantaan virus, with titers reaching levels of 128. The presence of leptospiral antibodies (by microagglutination test), which included the prevalence of antibodies to Leptospira icterohaemorrhagiae, L. bratislava, and L. saxkoening serotypes, was observed in 10-12% of the farmers and forestry workers in these Alpine mountain regions. Only a few sporadic clinical cases of leptospirosis have been reported from these regions. Antibodies to Borrelia burgdorferi (by IFA) were observed in 19% of the rangers and forestry workers, with lower values in farmers (10%) and hunters (8%). These data suggest the presence of a large number of asymptomatic infections with B. burgdorferi and the leptospires in the densely wooded areas of the Alpine Italian regions. Furthermore, the recent identification of a case of Hantaan acute nephropathy in a man living in the mountainous northeastern area of Italy confirms the presence of hantavirus in the Italian Alpine zones, especially those near the Slovenian border. AD - Institute of Tropical and Infectious Diseases, University La Sapienza, Rome, Italy. PMID- 8093990 CU - 94 SO - Am J Trop Med Hyg 1993 Jan;48(1):20-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 94346069 AU - Daiter AB AU - Shibalov VA AU - Stoianova NA AU - Sleptsova VI AU - Semenovich VN TI - [Leptospira infection under the natural conditions of the environs of Saint Petersburg] LA - Rus MH - Animal MH - Antibodies, Bacterial/blood MH - Carrier State/epidemiology/transmission/veterinary MH - Comparative Study MH - *Disease Reservoirs/statistics & numerical data/veterinary MH - Disease Vectors MH - English Abstract MH - Human MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/epidemiology/*transmission/veterinary MH - Rodent Diseases/epidemiology/transmission MH - Rodentia/immunology/microbiology MH - Russia/epidemiology MH - *Suburban Population/statistics & numerical data MH - *Urban Population/statistics & numerical data RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 940916 DP - 1993 Jan-Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 28-33 SB - M CY - RUSSIA IP - 1 JC - Y9O AA - Author EM - 9411 AB - The existence of valent natural foci of leptospirosis, stable and polyhostal, under the conditions of urban agglomerations has been established. In an intensively urbanized landscape, the foci of mixed (natural and anthropic) type can be found. Depending on the character of microlandscape in a given zone, the main hosts of leptospires are different species of small mammals in whose populations, as a rule, the circulation of at least three Leptospira species is observed. Introduction of the 'carriership index' will help determine the role of different species of small mammals as the potential source of leptospires in the foci, as well as the proportion of different circulating Leptospira species and their zonal distribution. PMID- 8067068 TT - Leptospiroznaia infektsiia v prirodnykh usloviiakh okrestnostei Sankt- Peterburga. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1993 Jan-Feb;(1):28-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 94287848 AU - Nagy G TI - Comparative pathogenicity study of Leptospira interrogans serovar pomona strains. LA - Eng MH - Animal MH - Comparative Study MH - Female MH - Hamsters MH - Leptospira interrogans/*pathogenicity MH - Leptospirosis/microbiology/*veterinary MH - Species Specificity MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 940725 DP - 1993 IS - 0236-6290 TA - Acta Vet Hung PG - 315-24 CY - HUNGARY IP - 3-4 VI - 41 JC - 27Q AA - Author EM - 9409 AB - The comparative pathogenicity study of two Leptospira interrogans serovar pomona strains isolated from pig herds of different epizootiological status is reported. Using monoclonal antibodies (Mabs), the isolates were identified as Leptospira interrogans serovar pomona. The results obtained for the reference strain of L. pomona were identical with those of the two isolates, with the exception of monoclonal serum designated 61-7, which gave a 1:30 titre with the reference strain. In a pig herd comprising 1,000 sows, strain XVIII caused abortion in 300 animals. In the hamster pathogenicity test, this strain killed the hamsters on postinoculation (PI) days 5 or 6. The pathogen was reisolated from their organs. Strain XV did not cause abortion in a herd of 600 sows; it only elicited seroconversion in a proportion of the animals (26 out of 274 blood samples were positive, corresponding to a seropositivity rate of 9.5%). This strain did not kill the hamsters and could be demonstrated from their organs neither by isolation nor by histological examination. The blood serum of two pregnant sows infected with strain XVIII contained high titres of antibodies (1:1,600 and 1:3,200) already on PI day 10. The first urine sample of these animals, taken on PI day 10, also contained large numbers of leptospires. The pathogen was reisolated from urine samples taken at 10-day intervals and from the kidneys of the slaughtered sows. One of the two infected sows delivered four non-viable and a viable piglet. From the kidneys of the non-viable piglets, leptospires were demonstrated by histological examination. In contrast, none of the four pregnant sows inoculated with strain XV aborted. The sows did not produce antibodies detectable by the microscopic agglutination test (MAT). The pathogen could not be isolated from urine samples and from kidney samples taken from the sows at slaughter. Histological demonstration of leptospires from the sows' kidneys also failed. AD - Central Veterinary Institute, Budapest, Hungary. PMID- 8017234 SO - Acta Vet Hung 1993;41(3-4):315-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 95099086 AU - Obregon Fuentes AM AU - Lopez Acosta C AU - Perez Herrera C TI - [Evaluation of the counterimmunoelectrophoresis technique for the serologic diagnosis of leptospirosis] LA - Spa MH - Antigens, Bacterial/blood MH - *Counterimmunoelectrophoresis MH - English Abstract MH - Human MH - Leptospira/immunology MH - Leptospirosis/blood/*diagnosis MH - Predictive Value of Tests MH - Sensitivity and Specificity MH - Serodiagnosis RN - 0 (Antigens, Bacterial) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE DA - 950123 DP - 1993 IS - 0375-0760 TA - Rev Cubana Med Trop PG - 67-71 CY - CUBA IP - 1 VI - 45 JC - RPX AA - Author EM - 9503 AB - The counterimmunoelectrophoresis (CIE) technic was assessed for leptospirosis serological diagnosis by using an antigenic preparation from Leptospira biflexa Patoc I strain. It was showed that the CIE technic had 82% sensitivity and 100% specificity. The antigen used showed a gender-specific reactivity on detecting antibodies in patients infected by different leptospirosis serogroups by microagglutination test. Antigen stability for CIE technic was 6 months without loss of titre. AD - Instituto de Medicina Tropical Pedro Kouri. PMID- 7800895 TT - Evaluacion de la tecnica de contrainmunoelectroforesis para el diagnostico serologico de la leptospirosis. EA - A SO - Rev Cubana Med Trop 1993;45(1):67-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [194 medline neighbors] UI - 95099078 AU - Martinez Sanchez R AU - Cruz de La Paz R AU - Lopez Acosta C TI - [Human leptospirosis behavior in Cuba] LA - Spa MH - Adolescence MH - Adult MH - Aged MH - Cuba/epidemiology MH - English Abstract MH - Female MH - Human MH - Incidence MH - Male MH - Middle Age MH - Risk Factors MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 950123 DP - 1993 IS - 0375-0760 TA - Rev Cubana Med Trop PG - 32-41 CY - CUBA IP - 1 VI - 45 JC - RPX AA - Author EM - 9503 AB - A description is made of the antecedents of human leptospirosis in Cuba and the behavior of the disease from 1981. An analysis with regards lethality and incidence during the five-year period 1986-1990 was carried out; the most affected provinces, the months of highest occurrence, and the most hazardous occupations, are listed. The present situation of human leptospirosis in Cuba is described and recommendations are provided. AD - Instituto de Medicina Tropical Pedro Kouri. PMID- 7800887 TT - Algunas consideraciones sobre el comportamiento de la leptospirosis humana en Cuba. EA - A SO - Rev Cubana Med Trop 1993;45(1):32-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 93104381 AU - Herrer Castejon A AU - Chueca Rodriguez C AU - Pueyo Salavera C AU - Arbues Palacios J TI - [Icterohemorrhagic leptospirosis. Detection of a case in an urban health center (letter)] LA - Spa MH - Case Report MH - Human MH - Male MH - Middle Age MH - Weil's Disease/*diagnosis PT - LETTER DA - 930128 DP - 1992 Dec IS - 0212-6567 TA - Aten Primaria PG - 1053-4 CY - SPAIN IP - 9 VI - 10 JC - A5F EM - 9303 PMID- 1467428 TT - Leptospirosis icterohemorragica. Deteccion de un caso en un centro de salud urbano. SO - Aten Primaria 1992 Dec;10(9):1053-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 93077435 AU - Baril C AU - Herrmann JL AU - Richaud C AU - Margarita D AU - Girons IS TI - Scattering of the rRNA genes on the physical map of the circular chromosome of Leptospira interrogans serovar icterohaemorrhagiae. LA - Eng MH - Base Sequence MH - *Chromosome Mapping MH - *Chromosomes, Bacterial MH - Cloning, Molecular MH - Deoxyribonucleases, Type II Site-Specific/metabolism MH - Genes, Bacterial/*genetics MH - Genome, Bacterial MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - RNA, Ribosomal/*genetics MH - Serotyping MH - Support, Non-U.S. Gov't RN - EC 3.1.21.- (endodeoxyribonuclease AscI) RN - EC 3.1.21.- (endodeoxyribonuclease NotI) RN - EC 3.1.21.- (endodeoxyribonuclease SrfI) RN - EC 3.1.21.4 (Deoxyribonucleases, Type II Site-Specific) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE DA - 921230 DP - 1992 Dec IS - 0021-9193 TA - J Bacteriol PG - 7566-71 SB - M CY - UNITED STATES IP - 23 VI - 174 JC - HH3 AA - Author EM - 9303 AB - Leptospira interrogans is a pathogenic bacterium with a low G+C content (34 to 39%). The restriction enzymes NotI, AscI, and SrfI cut the chromosome of L. interrogans serovar icterohaemorrhagiae into 13, 3, and 5 fragments separable by one- and two-dimensional pulsed-field gel electrophoresis (PFGE). The genome is composed of a circular 4.6-Mbp chromosome and a 0.35-Mbp extrachromosomal element. A physical map of the chromosome was constructed for NotI, AscI, and SrfI by using single and double digests, or partial NotI digests obtained at random or by cross-protection of NotI sites by FnuDII methylase, and linking clones. rRNA genes were found to be widely scattered on the chromosome. AD - Unite de Bacteriologie Moleculaire et Medicale, Institut Pasteur, Paris, France. PMID- 1447129 CU - 93 SO - J Bacteriol 1992 Dec;174(23):7566-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 93344556 AU - Dai B TI - Advances in research on leptospira and human leptospirosis in China. LA - Eng MH - Animal MH - China MH - Hemorrhage/etiology MH - Human MH - *Leptospira/classification/genetics/immunology MH - *Leptospirosis/complications MH - Lung Diseases/etiology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 930909 DP - 1992 Dec IS - 1001-9294 TA - Chin Med Sci J PG - 239-43 CY - ENGLAND IP - 4 VI - 7 JC - A8E AA - Author EM - 9311 AB - Leptospirosis exists in 26 of 30 provinces (exclusive of Taiwan province) in China. Up to now, a total of 18 serogroups and 70 serovars of pathogenic leptospires have been identified, including 35 serovars first found in China. A great deal of work has gone into the study of the leptospires and leptospirosis, and the present paper reviews these works, concentrating on serovar lai (the major serovar in China) and pulmonary diffuse hemorrhage (PDH), a traumatic consequence of leptospirosis. AD - Research Unit of Leptospirosis, West China University of Medical Sciences, Chengdu. RF - 22 PMID- 1307502 SO - Chin Med Sci J 1992 Dec;7(4):239-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 93290842 AU - Ruby KW AU - Cardella MA AU - Knudtson WU TI - Assay for measuring relative potency of leptospiral bacterins containing serovar pomona. LA - Eng MH - Animal MH - Antibodies, Monoclonal MH - Antigens, Bacterial/analysis MH - Bacterial Vaccines/*analysis/standards MH - Biological Assay/*methods MH - Enzyme-Linked Immunosorbent Assay/*methods MH - Evaluation Studies MH - Hamsters MH - Leptospira interrogans/classification/*immunology MH - Male MH - Mice MH - Mice, Inbred BALB C MH - Reference Standards MH - Serotyping MH - Weil's Disease/prevention & control RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 930721 DP - 1992 Dec IS - 1045-1056 TA - Biologicals PG - 259-66 SB - M CY - ENGLAND IP - 4 VI - 20 JC - AMW AA - Author EM - 9309 AB - An enzyme-linked immunosorbent assay (ELISA) was developed for the quantitation of leptospiral antigen in bacterins containing Leptospira interrogans serovar pomona type kennewicki. A monoclonal antibody (MAb), 2D7, which is directed against a surface antigen on whole cells of L. interrogans serovar pomona type kennewicki, was used in the assay. The capture of antigen in bacterins by a polyclonal antiserum was followed by the addition of the 2D7 ascites fluid, an anti-mouse conjugate and substrate. Biologicals evaluated with this system included preparations containing type kennewicki antigen (homologous) and those not containing type kennewicki antigen (heterologous). Heterologous bacterins gave optical density (OD) values comparable to those of blank wells. Homologous bacterins yielded OD values equal to or greater than those of the National Veterinary Services Laboratories (NVSL) reference pomona bacterin. The relative potencies (RP) of 84 licensed commercial Leptospira pomona bacterin serials were evaluated against the NVSL reference pomona bacterin using the NVSL Relative Potency computer program. Random samples of 1, 2, 3 and 5 ml dose products were selected for evaluation with this system. All products tested passed the hamster potency assay required for leptospiral bacterins. This ELISA system enables detection of antigen in bacterins containing L. interrogans serovar pomona type kennewicki and demonstrates the potential for in vitro testing of leptospiral bacterins. AD - National Veterinary Services Laboratories, U.S. Department of Agriculture, Ames, Iowa 50010. PMID- 1305402 SO - Biologicals 1992 Dec;20(4):259-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 93120837 AU - Alves VA AU - Gayotto LC AU - De Brito T AU - Santos RT AU - Wakamatsu A AU - Vianna MR AU - Sakata EE TI - Leptospiral antigens in the liver of experimentally infected guinea pig and their relation to the morphogenesis of liver damage. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Guinea Pigs MH - Keratin/analysis MH - Kupffer Cells/pathology MH - Leptospira interrogans/*immunology MH - Leptospirosis/*microbiology/*pathology MH - Liver/blood supply/*microbiology/*pathology MH - Liver Regeneration MH - Male MH - Mitochondria, Liver/pathology RN - 0 (Antigens, Bacterial) RN - 68238-35-7 (Keratin) PT - JOURNAL ARTICLE DA - 930209 DP - 1992 Dec IS - 0940-2993 TA - Exp Toxicol Pathol PG - 425-34 SB - M CY - GERMANY IP - 7 VI - 44 JC - BIR AA - Author EM - 9304 AB - In order to investigate the morphogenes of experimental leptospirosis by morphologic and immunohistologic methods, 24 guinea-pigs were inoculated intraperitoneally with L. interrogans serogroup Icterohaemorrhagiae. They were divided in 6 groups, sacrificed from the 1st to the 6th day of infection. Semiquantitative analyses of histopathological liver lesions were performed in 1 micron sections of tissue embedded in glycol-methacrylate. The distribution of leptospiral antigen (L. Ag) and its glycolipoprotein (GLP) was demonstrated by peroxidase-antiperoxidase on paraffin embedded tissue. Significant lesions appeared at the 4th day of infection, progressing to a peak on the 6th day. Inflammation was associated with injury of the portal triad. Liver cells showed either swelling or acidophilic degeneration and necrosis, together with loss of cell cohesion, leading to disarray of liver cell plates. Mitochondria were found progressively enlarged and irregularly distributed. L. Ag expression was parallel to the morphological changes. Portal distribution was significant at the 4th day and on later stages centrilobular localization became predominant. Spiral forms suggestive of intact leptospires were initially found but, chiefly at the 6th day, L. Ag was seen in granules, probably resulting from phagocytosis. GLP staining was similar to granular L. Ag in morphology, and distribution. Cytokeratin condensation was seen in liver cells with acidophilic necrosis and was marked in areas of disorganization of cell plates. Our findings lead us to hypothesize a direct leptospiral cytotoxic effect on endothelial and on liver-cell membranes. At first, leptospires themselves would induce subcellular changes acting mainly on membrane permeability. Afterwards, their granular forms, including GLP, would act as adjuvant factors. These findings demonstrate that the disarray of liver cell plates at the late phase of the disease is genuine. AD - Department of Pathology, Instituto Adolfo Lutz (S. Paulo Health Service), Sao Paulo Medical School, Brazil. PMID- 1282401 CU - 95 SO - Exp Toxicol Pathol 1992 Dec;44(7):425-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [11 nucleotide links] [208 medline neighbors] UI - 93119151 AU - Weller R AU - Bateson MM AU - Heimbuch BK AU - Kopczynski ED AU - Ward DM TI - Uncultivated cyanobacteria, Chloroflexus-like inhabitants, and spirochete-like inhabitants of a hot spring microbial mat. LA - Eng MH - Bacteria/classification/genetics/*isolation & purification MH - Base Sequence MH - Cyanobacteria/classification/genetics/*isolation & purification MH - DNA, Bacterial/chemistry/genetics MH - Gene Library MH - Heat MH - Molecular Sequence Data MH - Nucleic Acid Conformation MH - Phylogeny MH - RNA, Bacterial/genetics MH - RNA, Ribosomal, 16S/genetics MH - Sequence Homology, Nucleic Acid MH - Spirochaetales/classification/genetics/*isolation & purification MH - Support, U.S. Gov't, Non-P.H.S. MH - *Water Microbiology RN - 0 (DNA, Bacterial) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 930201 DP - 1992 Dec IS - 0099-2240 TA - Appl Environ Microbiol PG - 3964-9 SB - M CY - UNITED STATES IP - 12 VI - 58 JC - 6K6 AA - Author EM - 9304 AB - Analysis of 16S rRNA sequences retrieved as cDNA (16S rcDNA) from the Octopus Spring cyanobacterial mat has permitted phylogenetic characterization of some uncultivated community members, expanding our knowledge or diversity within this microbial community. Two new cyanobacterial 16S rRNA sequences were discovered, raising to four the number of cyanobacterial sequence types known to occur in the mat. None of the sequences found is that of the cultivated thermophilic cyanobacterium Synechococcus lividus. A new 16S rRNA sequence characteristic of green nonsulfur bacteria and their relatives was discovered, raising to two the number of such sequences known to exist in the mat. Both are unique among the 16S rRNA sequences of cultivated members of this group, including an Octopus Spring isolate of Chloroflexus aurantiacus and Heliothrix oregonensis, whose sequences we report herein. Two spirochete-like 16S rRNA sequences were discovered. One can be placed in the leptospira subdivision of the spirochete group, but the other has such a loose affiliation with the spirochete group that it might actually belong to an as yet unrecognized subdivision or even to a new eubacterial line of descent. AD - Department of Microbiology, Montana State University, Bozeman 59717. PMID- 1282313 CU - 95 SI - GENBANK/L04674 SI - GENBANK/L04675 SI - GENBANK/M62776 SI - GENBANK/L04709 SI - GENBANK/L04710 SI - GENBANK/M62775 SI - GENBANK/L04703 SI - GENBANK/L04704 SI - GENBANK/L04711 SI - GENBANK/L04712 SI - GENBANK/L05508 SI - GENBANK/L05509 SI - GENBANK/L05510 SI - GENBANK/L05930 SO - Appl Environ Microbiol 1992 Dec;58(12):3964-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 93088490 AU - Leonard FC AU - Quinn PJ AU - Ellis WA AU - O'Farrell K TI - Duration of urinary excretion of leptospires by cattle naturally or experimentally infected with Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Bacteriuria/microbiology/*veterinary MH - Cattle MH - Cattle Diseases/transmission/*urine MH - Female MH - Leptospira interrogans/growth & development/immunology/*isolation & purification MH - Leptospirosis/transmission/urine/*veterinary MH - Retrospective Studies MH - Seasons MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930107 DP - 1992 Nov 7 IS - 0042-4900 TA - Vet Rec PG - 435-9 SB - M CY - ENGLAND IP - 19 VI - 131 JC - XBS AA - Author EM - 9303 AB - The excretion of Leptospira interrogans serovar hardjo in the urine of cattle was studied in naturally and experimentally infected animals. Five of 15 naturally infected animals with microscopic agglutination test titres of > or = 1:300 shed leptospires for between 28 and 40 weeks. Twenty yearling heifers, experimentally infected by either the supraconjunctival or intrauterine routes, shed leptospires for from eight to 60 weeks; the 10 infected via the uterus shed L interrogans serovar hardjo for a mean of 26 weeks (range eight to 54 weeks) and the 10 infected by the supraconjunctival route shed the organism for a mean of 32 weeks (range 12 to 60 weeks). The results suggest that natural infection results in more prolonged excretion than experimental infection. No intermittent or seasonal excretion of the organism was observed. After the initial experimental infection, large numbers of leptospires were shed in the urine for several weeks, and thereafter there was a progressive decline in the number of organisms shed. AD - Moorepark Research and Development Centre, Fermoy, County Cork. PMID- 1455593 SO - Vet Rec 1992 Nov 7;131(19):435-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 93111921 AU - Lange S TI - [Seroepidemiological studies of the detection of leptospires of the sejroe group in cattle in middle Thuringia] LA - Ger MH - Abortion, Veterinary/*microbiology MH - Animal MH - Antibodies, Bacterial/blood MH - Cattle MH - Cattle Diseases/*epidemiology/microbiology MH - English Abstract MH - Female MH - Germany/epidemiology MH - Leptospira interrogans/*classification MH - Leptospirosis/epidemiology/*veterinary MH - Pregnancy MH - Prevalence RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930127 DP - 1992 Nov 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 374-7 CY - GERMANY IP - 11 VI - 105 JC - 9Q8 AA - Author EM - 9303 AB - From 1983 to 1989 14,361 head of cattle from the middle Thuringia region were investigated by means of microagglutination test for the presence of Leptospira serovars hardjo, saxkoebing and sejroe. 4,484 samples from cattle with abortion (1983-1985) and a random sample of 5,284 cattle sera (1985) were investigated giving priority to L. hardjo. Furthermore 3,293 samples from cattle with abortion (1986/87) and a random samples test of 1,300 cattle sera (1989) were tested giving priority to L. saxkoebing. 2.5 percent of the cows having aborted and 10.3 percent of cattle tested out of the whole livestock showed antibodies against L. hardjo. The test for presence of L. saxkoebing demonstrated in cattle with abortion a seroprevalence of 14 percent and in the random samples tests a portion of reagents of 11.3 percent. The degree of infection differed regionally, the highest degree was found in livestocks of the northern part of the Thuringia forest. The prevalence of L. saxkoebing in cattle with abortion from large dairy farms was 18.6 percent, which is higher than the average in the region examined. Antibodies against hardjo and sejroe were interpreted as caused by cross reactivity. AD - Institut fur Veterinarwesen, Bad Langensalza. PMID- 1471971 TT - Seroepidemiologische Untersuchungen zum Nachweis von Leptospiren der Sejroe-Gruppe bei Rindern in Mittel-Thuringen. EA - A SO - Berl Munch Tierarztl Wochenschr 1992 Nov 1;105(11):374-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 93103178 AU - Kvasnicka WG AU - Hanks D AU - Huang JC AU - Hall MR AU - Sandblom D AU - Chu HJ AU - Chavez L AU - Acree WM TI - Clinical evaluation of the efficacy of inoculating cattle with a vaccine containing Tritrichomonas foetus. LA - Eng MH - Abortion, Veterinary/*prevention & control/parasitology MH - Animal MH - Antibodies, Protozoan/blood MH - Cattle MH - Cattle Diseases/immunology/*prevention & control/parasitology MH - Female MH - Fertilization MH - Mastigophora Infections/immunology/prevention & control/*veterinary MH - Pregnancy MH - Protozoan Vaccines/*immunology MH - Tritrichomonas foetus/*immunology RN - 0 (Antibodies, Protozoan) RN - 0 (Protozoan Vaccines) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - RANDOMIZED CONTROLLED TRIAL DA - 930119 DP - 1992 Nov IS - 0002-9645 TA - Am J Vet Res PG - 2023-7 SB - M CY - UNITED STATES IP - 11 VI - 53 JC - 40C AA - Author EM - 9303 AB - To test the efficacy of a polyvalent Tritrichomonas foetus vaccine, 130 nulliparous heifers were randomly assigned to either receive the test T foetus vaccine or to serve as nonvaccinated controls. The polyvalent test vaccine consisted of a Campylobacter fetus/Leptospira canicola- grippotyphosa-hardjo-icterohaemorrhagiae-pamona bacterine containing 5 x 10(7) killed T foetus/dose. The polyvalent control vaccine consisted of the aforementioned formulation without T foetus. Heifers were administered 2 doses of control or experimental vaccine at 3-week intervals. Heifers were bred to T foetus-infected bulls and their conception and pregnancy rates were determined throughout gestation. In addition, serum samples were analyzed to determine induced concentrations of antitrichomonal antibodies and vaginal secretions were sampled to determine T foetus infection rates in control and vaccinated animals. One week after each of the 15-day breeding periods, 60% (6 of 10) of tested vaccinates and 80% (8 of 10) of tested control animals were T foetus culture-positive. The mean duration of infection of vaccinates was 3.8 weeks (+/- 7.5 days), compared with 5.4 weeks (+/- 7.5 days) of infection for control heifers. All vaccinates developed increased immunofluorescence and serum neutralizing antibody titers following the first immunization, and had additional increases of at least fourfold in response to the second injection. In contrast, no consistent increase in immunofluorescence or serum neutralizing antibodies was observed in control animals. Conception rates were 89.2% for vaccinates and 85.9% for control animals 30 days after breeding and 80 to 90% of these remained pregnant 60 days after breeding.(ABSTRACT TRUNCATED AT 250 WORDS) AD - School of Veterinary Medicine, College of Agriculture, University of Nevada, Reno 98557. PMID- 1466496 SO - Am J Vet Res 1992 Nov;53(11):2023-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 93076259 AU - Christianson WT TI - Stillbirths, mummies, abortions, and early embryonic death. LA - Eng MH - Abortion, Veterinary/economics/*etiology MH - Animal MH - Female MH - Fetal Death/economics/etiology/*veterinary MH - Infection/complications/*veterinary MH - Mummies MH - Pregnancy MH - Swine MH - Swine Diseases/economics/*etiology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 921229 DP - 1992 Nov IS - 0749-0720 TA - Vet Clin North Am Food Anim Pract PG - 623-39 SB - M CY - UNITED STATES IP - 3 VI - 8 JC - CFP AA - Author EM - 9303 AB - Stillbirths, mummies, abortions, and early embryonic death have a substantial impact on the profitability of a farm in both endemic and epidemic conditions. Fetal death is highly dependent on stage of gestation. Implantation occurs around day 14 postmating in sows, and fetal death of an entire litter at this time usually results in a regular return to service. If more than four embryos remain alive, the sow may go on to farrow normally. If fetal death occurs after implantation but before calcification (around 35 days gestation), the sow will either return to estrus at an irregular interval or will farrow a normal litter of reduced size. Although fetuses are normally resorbed prior to calcification, fetal death after that stage of development leads to mummification. Abortions are more directly related to maternal control of pregnancy than fetal failure. Stillbirths are those pigs that appear normal at birth but have lungs that do not float in water. Causes of fetal death can be divided into infectious and noninfectious categories. Infectious causes perhaps are overemphasized but are certainly important in epidemic situations. Some infectious causes of fetal death are primarily systemic maternal pathogens, whereas others may attack the fetus and/or placenta, directly such as PPV, PEV, PRV, SIRS virus, and Leptospira sp. Several other infectious agents have been associated with fetal death. Noninfectious causes of stillborns, mummies, abortions, and early embryonic death are most common in endemic situations. Most stillbirths are due to difficulty at or around parturition, primarily extended duration causing fetal anoxia. Environmental factors such as increased ambient temperature and seasonal infertility affect death rates, as do specific individual sow characteristics, nutritional factors, and toxicities. The causes of stillborns, mummies, abortions, and early embryonic death are often difficult to ascertain, but the potential rewards make investigation efforts worthwhile. AD - Department of Clinical and Population Sciences, University of Minnesota College of Veterinary Medicine, St. Paul. RF - 49 PMID- 1446274 SO - Vet Clin North Am Food Anim Pract 1992 Nov;8(3):623-39 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 93054010 AU - Divers TJ AU - Byars TD AU - Shin SJ TI - Renal dysfunction associated with infection of Leptospira interrogans in a horse. LA - Eng MH - Animal MH - Antibiotics/therapeutic use MH - Case Report MH - Fluid Therapy/veterinary MH - Horse Diseases/*etiology/therapy MH - Horses MH - Kidney/physiopathology MH - Kidney Failure, Acute/etiology/therapy/*veterinary MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/complications/therapy/*veterinary MH - Male RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 921223 DP - 1992 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1391-2 SB - M CY - UNITED STATES IP - 9 VI - 201 JC - HAV AA - Author EM - 9302 AB - Renal failure associated with infection of Leptospira interrogans was detected in a horse. Fever, leukocytosis, pyuria, isosthenuria, and azotemia were suggestive of an inflammatory urinary tract disease. Despite persistent pyuria, no bacteria were found during routine microscopic examinations or bacteriologic culturing of urine. A fluorescent antibody examination of the urine was positive for L interrogans. Serologic testing during a 6-month period, supported an acute infection with L interrogans serovar pomona. Treatment with intravenously administered fluids and antimicrobials resulted in clinical recovery. Leptospira interrogans serovar pomona has been reported as causing fever, uveitis, or abortion in horses. AD - Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853. PMID- 1429185 SO - J Am Vet Med Assoc 1992 Nov 1;201(9):1391-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 93088476 AU - Little TW AU - Hathaway SC AU - Boughton ES AU - Seawright D TI - Development of a control strategy for Leptospira hardjo infection in a closed beef herd. LA - Eng MH - Age Factors MH - Animal MH - Antibodies, Bacterial/blood MH - Bacterial Vaccines MH - Cattle MH - Cattle Diseases/epidemiology/*prevention & control MH - Dihydrostreptomycin Sulfate/therapeutic use MH - Female MH - Leptospira/classification/*immunology MH - Leptospirosis/epidemiology/prevention & control/*veterinary MH - Male MH - Prevalence MH - Quarantine MH - Scotland/epidemiology MH - Vaccination/veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) RN - 5490-27-7 (Dihydrostreptomycin Sulfate) PT - JOURNAL ARTICLE DA - 930104 DP - 1992 Oct 24 IS - 0042-4900 TA - Vet Rec PG - 383-6 SB - M CY - ENGLAND IP - 17 VI - 131 JC - XBS AA - Author EM - 9303 AB - Serological evidence of infection with a leptospire belonging to the Sejroe serogroup was identified in a closed population of Luing cattle in the west of Scotland, and the geographical isolation of the population presented an opportunity to control and possibly eradicate the infection in a large beef herd farmed under extensive conditions. Serological and bacteriological studies revealed that infection was present at a high level throughout the herd, and that the infecting serovar was hardjo. Unlike endemic hardjo infection in dairy herds, new infections were still occurring in older age-groups. Investigations of other domestic and free-living species sharing the habitat demonstrated that the maintenance of an endemic focus of hardjo was restricted to the cattle. Changes in management to prevent the transmission of infection to successive cohorts of young animals were impractical and risky, and antibiotic treatment followed by removal to clean pasture failed to prevent new cases. Thus vaccination offered the only means of control and possible eradication, and the epidemiological characteristics of the infection dictated that the programme be applied to the whole herd. AD - Central Veterinary Laboratory, Ministry of Agriculture Fisheries and Food, Addlestone, Surrey. PMID- 1280875 CU - 95 SO - Vet Rec 1992 Oct 24;131(17):383-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 93136555 AU - Palmer M AU - Hookey J TI - The chemiluminescent detection of leptospiral antigen. LA - Eng MH - Antigens, Bacterial/*analysis/blood/urine MH - Chemiluminescence MH - Cross Reactions MH - Evaluation Studies MH - Human MH - Immunoassay/*methods MH - Leptospira interrogans/*immunology MH - Photometry/*methods MH - Sensitivity and Specificity RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 930219 DP - 1992 Oct IS - 0934-8840 TA - Int J Med Microbiol Virol Parasitol Infect Dis PG - 300-8 SB - M CY - GERMANY IP - 3 VI - 277 JC - BD7 AA - Author EM - 9304 AB - The aim of this study was to investigate the feasibility of using enhanced chemiluminescence for the rapid detection of leptospiral antigen (L. interrogans serovar hardjo) in biological fluids, and to assess the suitability of such an assay for the early diagnosis of human leptospiral infections. The limit of detection for homologous antigen in phosphate buffered saline was 9 x 10(4) leptospires/ml. In human blood the sensitivity remained unchanged throughout the sampling time, (1.8 x 10(5) leptospires/ml), but decreased with time in human urine. The assay did not cross-react with other members of the Leptospira interrogans species, was unaffected by the presence of biological fluids but the sensitivity was reduced by contaminating bacteria. The assay was both rapid and sensitive, when compared with current cultural techniques, and offers a potentially valuable aid to the early diagnosis of leptospirosis. AD - WHO/FAO Collaborating Centre for Research and Reference on Leptospirosis County Hospital, Hereford, England. PMID- 1486231 SO - Int J Med Microbiol Virol Parasitol Infect Dis 1992 Oct;277(3):300-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 93116169 AU - Holzman S AU - Conroy MJ AU - Davidson WR TI - Diseases, parasites and survival of coyotes in south-central Georgia. LA - Eng MH - Animal MH - Antibodies, Protozoan/blood MH - Antibodies, Viral/blood MH - *Carnivora/parasitology MH - Cause of Death MH - Dirofilariasis/*epidemiology MH - Female MH - Georgia/epidemiology MH - Male MH - Parasitic Diseases/epidemiology/*veterinary MH - Prevalence MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Toxoplasma/immunology MH - Toxoplasmosis, Animal/epidemiology MH - Virus Diseases/epidemiology/*veterinary RN - 0 (Antibodies, Protozoan) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 930129 DP - 1992 Oct IS - 0090-3558 TA - J Wildl Dis PG - 572-80 SB - M CY - UNITED STATES IP - 4 VI - 28 JC - KEM AA - Author EM - 9304 AB - Serologic testing, radio-telemetry and post-mortem diagnostic evaluations were used to investigate survival and causes of mortality among 17 coyotes (Canis latrans) in south-central Georgia (USA). Prevalence of canine heartworm (Dirofilaria immitis) microfilariae was lower (P = 0.057) among fall-captured (22%) than among winter-captured (75%) coyotes. Prevalence of heartworm was higher among adults than juveniles in the fall, but no significant difference was detected between animals captured in winter. Antibodies were found against canine parvovirus (65%), canine parainfluenza virus (59%), infectious canine hepatitis virus (41%), and Toxoplasma gondii (18%). Antibodies were not found to Brucella canis, canine coronavirus, five serovars of Leptospira interrogans, or canine distemper virus. Seroprevalence of canine parvovirus was lower (P = 0.009) among fall-captured animals (33%) than winter-captured animals (100%). The Kaplan-Meier estimate of annual survival was 0.500 for all animals. Juvenile survival did not differ (P = 0.79) from adult survival, but male survival (S = 0.217) was lower (P = 0.11) than female survival (S = 0.804). Two of nine (22%) mortalities were human-caused, one was due to concurrent canine parvovirus and canine distemper virus infections, one animal died of trauma, two were considered natural mortalities of unknown cause, and no cause of death could be determined for the remaining three animals. Natural mortality may be significant for coyotes in south-central Georgia, although there was no apparent link between exposure to pathogens and the animals' subsequent fate in our small sample. AD - School of Forest Resources, University of Georgia, Athens 30602. PMID- 1474655 SO - J Wildl Dis 1992 Oct;28(4):572-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 93088530 AU - Gitton X AU - Andre-Fontaine G AU - Andre F AU - Ganiere JP TI - Immunoblotting study of the antigenic relationships among eight serogroups of Leptospira. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis/chemistry MH - Cattle MH - Dogs MH - Electrophoresis, Polyacrylamide Gel MH - Immunoblotting MH - Leptospira/classification/*immunology MH - Leptospira interrogans/classification/*immunology MH - Molecular Weight MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 930106 DP - 1992 Oct IS - 0378-1135 TA - Vet Microbiol PG - 293-303 SB - M CY - NETHERLANDS IP - 3-4 VI - 32 JC - XBW AA - Author EM - 9303 AB - Seven strains of Leptospira interrogans belonging to seven different serogroups, and one strain of Leptospira biflexa were analysed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) with gradient gels and immunoblotting with hyperimmune rabbit sera raised against each strain. The molecular masses of the proteins were calculated with a polynomial regression model. The SDS-PAGE patterns of the L. interrogans strains were similar and characterized by 24 common bands. This profile was not found for L. biflexa. The immunoblots obtained either with the seven anti-L. interrogans sera or the anti-L. biflexa serum allowed a clear distinction between the two species. Taken as a whole, the L. interrogans strain patterns revealed by the seven anti-L. interrogans sera were similar, sharing eight common major bands. A serovar- or serogroup-specific antigenic zone, ranging from 21 to 26 kDa, was also identified. AD - National Veterinary School of Nantes, France. PMID- 1455625 SO - Vet Microbiol 1992 Oct;32(3-4):293-303 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 93085656 AU - Leary BD TI - Leptospirosis--a cause for concern? [letter] LA - Eng MH - Borneo/epidemiology MH - Great Britain MH - Human MH - Incidence MH - Leptospirosis/*epidemiology MH - *Military Personnel MH - War PT - LETTER DA - 930106 DP - 1992 Oct IS - 0035-8665 TA - J R Army Med Corps PG - 152 SB - M CY - ENGLAND IP - 3 VI - 138 JC - JV6 EM - 9303 PMID- 1453387 SO - J R Army Med Corps 1992 Oct;138(3):152 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 93085655 AU - Finnegan TP TI - Leptospirosis [letter] LA - Eng MH - Great Britain MH - Human MH - Leptospirosis/*drug therapy/prevention & control MH - *Military Personnel PT - LETTER DA - 930106 DP - 1992 Oct IS - 0035-8665 TA - J R Army Med Corps PG - 151-2 SB - M CY - ENGLAND IP - 3 VI - 138 JC - JV6 EM - 9303 PMID- 1453386 SO - J R Army Med Corps 1992 Oct;138(3):151-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 93069964 AU - Parma AE AU - Cerone SI AU - Sansinanea SA AU - Ghezzi M TI - C3 fixed in vivo to cornea from horses inoculated with Leptospira interrogans. LA - Eng MH - Animal MH - Cells, Cultured MH - Complement Fixation Tests/veterinary MH - Complement 3/*immunology MH - Cornea/*immunology/microbiology MH - Corneal Opacity/veterinary MH - Epithelium/immunology/microbiology MH - Eye Infections, Bacterial/immunology/microbiology/*veterinary MH - Fluorescent Antibody Technique/veterinary MH - Horse Diseases/*immunology/microbiology MH - Horses MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/*veterinary MH - Male MH - Support, Non-U.S. Gov't MH - Uveitis/veterinary RN - 0 (Complement 3) PT - JOURNAL ARTICLE DA - 921216 DP - 1992 Oct IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 181-7 SB - M CY - NETHERLANDS IP - 1-2 VI - 34 JC - XCB AA - Author EM - 9302 AB - C3 was detected bound in vivo to the opaque cornea of horses inoculated with killed Leptospira interrogans. Employing epithelial corneal cells isolated from a monolayer in tissue culture, we proved that C3 is fixed in vitro to the intact cell surface after incubation with a fresh equine anti-Leptospira serum. These findings, in addition to the infiltration of cornea with neutrophils and lymphocytes, may explain the mechanisms of tissue damage in recurrent uveitis of horses with leptospirosis. AD - Lab. Inmunoquimica y Biotecnologia, Facultad Cs. Veterinarias, Univ. Nac. del Centro PBA, Tandil, Argentina. PMID- 1441226 SO - Vet Immunol Immunopathol 1992 Oct;34(1-2):181-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 93047825 AU - Venkataraman KS AU - Nedunchelliyan S TI - Epidemiology of an outbreak of leptospirosis in man and dog. LA - Eng MH - Animal MH - Child MH - Child, Preschool MH - *Disease Outbreaks/veterinary MH - Dog Diseases/*epidemiology/microbiology/transmission MH - Dogs MH - Female MH - Human MH - India/epidemiology MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology/microbiology/transmission/veterinary MH - Male MH - Marsupialia/microbiology MH - Muridae/microbiology MH - Seroepidemiologic Methods PT - JOURNAL ARTICLE DA - 921215 DP - 1992 Oct IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 243-7 SB - M CY - ENGLAND IP - 4 VI - 15 JC - DNN AA - Author EM - 9302 AB - An outbreak of leptospirosis in man and dog occurred during the monsoon in Madras city, India. 48 (50.5%) of the 95 human sera tested were positive for leptospirosis. Of these, 32 showed the presence of agglutinin to serovar icterohaemorrhagiae. 20 (21.3%) of the 94 canine sera tested were positive for leptospirosis. Of these, 10 had agglutinins to serovar icterohaemorrhagiae and 9 to serovar canicola. Among murine reservoirs, 8 (25%) of 32 rat sera and 10 (41.6%) of 24 bandicoot sera were positive. Bandicoot and rat sera contained 70 and 50% of agglutinins to serovar icterohaemorrhagiae, respectively. Urine culture lead to isolate a icterohaemorrhagiae strain from a patient and a canicola one from a dog. The changing trends of epidemiology in the transmission of leptospirosis to man and dog has been discussed. AD - Department of Preventive Medicine, Veterinary College and Research Institute, Namakkal, India. PMID- 1424559 SO - Comp Immunol Microbiol Infect Dis 1992 Oct;15(4):243-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 93041199 AU - De Brito T AU - Prado MJ AU - Negreiros VA AU - Nicastri AL AU - Sakata EE AU - Yasuda PH AU - Santos RT AU - Alves VA TI - Detection of leptospiral antigen (L. interrogans serovar copenhageni serogroup Icterohaemorrhagiae) by immunoelectron microscopy in the liver and kidney of experimentally infected guinea-pigs. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Guinea Pigs MH - Kidney/*immunology/ultrastructure MH - Leptospira interrogans/*immunology MH - Liver/*immunology/ultrastructure MH - Microscopy, Immunoelectron RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 921222 DP - 1992 Oct IS - 0959-9673 TA - Int J Exp Pathol PG - 633-42 SB - M CY - ENGLAND IP - 5 VI - 73 JC - AW3 AA - Author EM - 9302 AB - Guinea-pigs were experimentally infected with L. interrogans serovar copenhageni serogroup Icterohaemorrhagiae and their liver and kidney were studied by immunoelectron microscopy using the post embedding indirect immunogold labelling technique. Primary antibody was a purified rabbit anti-serum produced against the same leptospiral strain used in the inoculum. Gold-labelled leptospiral antigen (LAg) was found close to cell membranes of hepatocytes, kidney tubular cells and endothelial cells of the interstitial capillaries of the kidney. Afterwards it was internalized by hepatic and tubular cells, and eventually found in lysosomes. Phagolysosomes of Kupffer cells were also found to contain remnants of degraded leptospires and gold- labelled LAg. Gold-labelled intact leptospires were detected at the enlarged intercellular spaces between hepatocytes at the areas of hepatic cell plate disarray, showing the potential for leptospiral migration during the septicaemic phase of the disease potentially contributing to the pathogenesis of the lesions. The affinity of leptospiral antigenic material for cell membranes suggests an initial interaction with cell surface proteins followed by its internalization and cell damage. The nature of antigenic material detected, however, remains undefined; it may be a toxin, an enzyme or any other factor/s involved in leptospiral virulence. AD - Department of Pathology, Hospital das Clinicas, S. Paulo, Brazil. PMID- 1419779 SO - Int J Exp Pathol 1992 Oct;73(5):633-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 94052883 AU - Goncalves AJ AU - de Carvalho JE AU - Guedes e Silva JB AU - Rozembaum R AU - Vieira AR TI - [Hemoptysis and the adult respiratory distress syndrome as the causes of death in leptospirosis. Changes in the clinical and anatomicopathological patterns] LA - Por MH - Adult MH - Brazil/epidemiology MH - Case Report MH - Cause of Death MH - English Abstract MH - Fatal Outcome MH - Female MH - Hemoptysis/etiology/mortality/*pathology MH - Human MH - Leptospirosis/complications/mortality/*pathology MH - Male MH - Middle Age MH - Respiratory Distress Syndrome, Adult/etiology/mortality/*pathology MH - Weil's Disease/complications/mortality/*pathology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW OF REPORTED CASES DA - 931216 DP - 1992 Oct-Dec IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 261-70 CY - BRAZIL IP - 4 VI - 25 JC - RET AA - Author EM - 9402 AB - Human leptospirosis, one of the main urban endemics/epidemics in Brazil, has dramatically grown in the last three decades, especially after floods caused by summer rains. This presentation describes recent changes in the clinical patterns of this pathology in our region, expressed by the emergence of massive haemoptysis and acute respiratory distress syndrome, or both conditions associated. The evident changes in the respiratory structures emerged as a serious life threat and death mechanisms, becoming the main cause of death in leptospirosis among us because of their high incidence. This new face of the disease demands a revision of current concepts about its seriousness and raises speculations about the pathogenesis of such alterations. AD - Hospital dos Servidores do Estado, Rio de Janeiro. RF - 62 PMID- 1340542 TT - Hemoptise/s e sindrome de angustia respiratoria do adulto como causas de morte na leptospirose. Mudancas de padroes clinicos e anatomopatologicos. EA - A SO - Rev Soc Bras Med Trop 1992 Oct-Dec;25(4):261-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 94052881 AU - Vasconcelos LM AU - Cisalpino EO AU - Vieira MN AU - Koury MC TI - [Anti-Leptospira agglutinins in different professional groups in the city of Londrina, Parana] LA - Por MH - Agglutination Tests MH - Agglutinins/*blood MH - Brazil/epidemiology MH - Comparative Study MH - English Abstract MH - Human MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/immunology MH - *Occupations/statistics & numerical data MH - Seroepidemiologic Methods MH - *Urban Population/statistics & numerical data RN - 0 (Agglutinins) PT - JOURNAL ARTICLE DA - 931216 DP - 1992 Oct-Dec IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 251-5 CY - BRAZIL IP - 4 VI - 25 JC - RET AA - Author EM - 9402 AB - Serum samples were obtained from 208 individuals in Londrina, Parana, Brazil. The serum were analysed for leptospiral agglutinins by agglutination microscopic tests and 28.4% were positive. The highest positivity was found for the serum of garbage collector (46.7%). AD - Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil. PMID- 1340540 TT - Pesquisa de aglutininas antileptospira em diferentes grupos profissionais na cidade de Londrina, Parana. EA - A SO - Rev Soc Bras Med Trop 1992 Oct-Dec;25(4):251-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 92395063 AU - Scully WE TI - Leptospirosis in aseptic meningitis [letter; comment] LA - Eng MH - Human MH - *Leptospirosis MH - Meningitis, Aseptic/*microbiology PT - COMMENT PT - LETTER DA - 921013 DP - 1992 Sep 30 IS - 8750-2836 TA - Hosp Pract (Off Ed) PG - 19 SB - A SB - M CY - UNITED STATES IP - 9A VI - 27 JC - HPO EM - 9212 CM - Comment on: Hosp Pract (Off Ed) 1992 May 30;27(5A):27-39 RO - M:LC1 PMID- 1522167 LR - 930210 SO - Hosp Pract (Off Ed) 1992 Sep 30;27(9A):19 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 93189435 AU - Halota W AU - Lapniewska E AU - Opoka J TI - [Epidemiologic and clinical aspects of leptospirosis with reference to personal observations] LA - Pol MH - Adolescence MH - Adult MH - Female MH - Human MH - Incidence MH - Leptospirosis/*diagnosis/epidemiology MH - Male MH - Middle Age MH - Poland/epidemiology MH - Seasons PT - JOURNAL ARTICLE DA - 930405 DP - 1992 Sep 7-14 IS - 0032-3756 TA - Pol Tyg Lek PG - 796-7 CY - POLAND IP - 36-37 VI - 47 JC - PBY EM - 9306 AD - Kliniki Chorob Zakaznych AM, Bydgoszczy. PMID- 1293564 TT - Epidemiologiczne i kliniczne aspekty leptospirozy z uwzglednieniem obserwacji wlasnych. SO - Pol Tyg Lek 1992 Sep 7-14;47(36-37):796-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 92406018 AU - Acuna J AU - Rojas J AU - Amaro AM AU - Toledo H AU - Jerez CA TI - Chemotaxis of Leptospirillum ferrooxidans and other acidophilic chemolithotrophs: comparison with the Escherichia coli chemosensory system. LA - Eng MH - Bacterial Proteins/genetics/metabolism MH - Base Sequence MH - *Chemotaxis MH - Comparative Study MH - DNA, Bacterial MH - Electrophoresis, Polyacrylamide Gel MH - Escherichia coli/genetics/*physiology MH - Leptospira/genetics/*physiology MH - Membrane Proteins/genetics/metabolism MH - Metals/pharmacology MH - Methylation MH - Molecular Sequence Data MH - Sequence Homology, Nucleic Acid MH - Support, Non-U.S. Gov't RN - 0 (Bacterial Proteins) RN - 0 (DNA, Bacterial) RN - 0 (Membrane Proteins) RN - 0 (Metals) RN - 0 (Tar protein) PT - JOURNAL ARTICLE DA - 921019 DP - 1992 Sep 1 IS - 0378-1097 TA - FEMS Microbiol Lett PG - 37-42 SB - M CY - NETHERLANDS IP - 1 VI - 75 JC - FML AA - Author EM - 9212 AB - Ni2+, Fe2+ and Cu2+ were attractants and aspartate was an apparent repellent for Leptospirillum ferrooxidans, a behaviour opposite to that for Escherichia coli. Membranes from L. ferrooxidans contained proteins with a molecular mass in the range of 80 kDa which were methylated in vitro. Methylation was stimulated in the presence of a membrane-free extract from E. coli, showing the response pattern expected for L. ferrooxidans, increased methylation by Ni2+, and demethylation by aspartate. This suggests the existence of sensory transducers having a common methylation domain with the E. coli methyl-accepting chemotaxis proteins. Total chromosomal DNA digests from L. ferrooxidans, Thiobacillus ferrooxidans and T. thiooxidans hybridized with probes containing different domains of the tar gene from E. coli, implying the presence of tar type genes in the acidophilic bacteria studied. AD - Departamento de Bioquimica, Facultad de Medicina, Universidad de Chile, Santiago. PMID- 1526464 CU - 92 GS - tar SO - FEMS Microbiol Lett 1992 Sep 1;75(1):37-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 93118147 AU - da Silva MV AU - Dias Camargo E AU - Vaz AJ AU - Batista L TI - Immunodiagnosis of human leptospirosis using saliva. LA - Eng MH - Antibodies, Bacterial/*analysis MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - IgG/*analysis MH - Immunologic Tests MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/immunology MH - Saliva/*immunology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 930201 DP - 1992 Sep-Oct IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 560-1 SB - M CY - ENGLAND IP - 5 VI - 86 JC - WBU AA - Author EM - 9304 AB - When the enzyme-linked immunosorbent assay for the detection of specific immunoglobulin M class antibodies was applied to paired saliva and serum samples from 40 patients with leptospirosis, positivity was 87.5% and 100%, respectively. No positive result was obtained with any saliva or serum sample from 60 individuals used as controls. These results suggest the alternative use of saliva for diagnosis and for epidemiological studies of human leptospirosis. AD - Secao de Sorologia, Instituto Adolfo Lutz, Sao Paulo, Brazil. PMID- 1475834 SO - Trans R Soc Trop Med Hyg 1992 Sep-Oct;86(5):560-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 93118146 AU - Perolat P AU - Reeve PA TI - First evidence of leptospirosis in Vanuatu. LA - Eng MH - Adult MH - Case Report MH - Dengue/*diagnosis/epidemiology MH - Diagnosis, Differential MH - Disease Outbreaks MH - Female MH - Human MH - Leptospirosis/*diagnosis/epidemiology MH - Male MH - Vanuatu/epidemiology PT - JOURNAL ARTICLE DA - 930201 DP - 1992 Sep-Oct IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 557-9 SB - M CY - ENGLAND IP - 5 VI - 86 JC - WBU AA - Author EM - 9304 AB - The clinical picture of leptospirosis is often confusing and biological confirmation with reference tests (microagglutination test or isolation of the organism) is not usually possible in tropical countries where the disease remains undiagnosed. We report here the first human cases of leptospirosis in Vanuatu (South Pacific), which occurred during the 1989-1990 epidemic of dengue, and discuss the differential diagnosis of the 2 diseases. AD - Leptospira Laboratory, Institute Pasteur de Nouvelle Caledonie, Noumea, New Caledonia. PMID- 1475833 SO - Trans R Soc Trop Med Hyg 1992 Sep-Oct;86(5):557-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 93050078 AU - Cinco M AU - Balanzin D AU - Banfi E TI - Evaluation of an immunoenzymatic test (ELISA) for the diagnosis of leptospirosis in Italy. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Blotting, Western MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel MH - *Enzyme-Linked Immunosorbent Assay MH - Evaluation Studies MH - Human MH - IgG/analysis MH - IgM/analysis MH - Italy MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis/immunology MH - Sodium Dodecyl Sulfate RN - 0 (Antibodies, Bacterial) RN - 0 (IgG) RN - 0 (IgM) RN - 151-21-3 (Sodium Dodecyl Sulfate) PT - JOURNAL ARTICLE DA - 921216 DP - 1992 Sep IS - 0392-2990 TA - Eur J Epidemiol PG - 677-82 SB - M CY - ITALY IP - 5 VI - 8 JC - ERE AA - Author EM - 9302 AB - An enzyme-linked immunosorbent assay (ELISA) was assessed to detect in humans IgM and IgG against the main serogroups/serovars of Leptospira present in Italy. Sonicated antigens from strain Wijnberg, serogroups Icterohaemorrhagiae and Riccio 2, serogroup Australis, were used in ELISA and the results were compared to microagglutination test (MAT). IgM were confirmed to be the predominant class of antibodies; the total sensitivity obtained by Wijnberg/ELISA with the sera of patients infected by different serogroups was 81.5% in relation to MAT, better sensitivity was achieved by the use of Riccio 2/ELISA; no reaction occurred with the control sera. Cross-reactivity was noted with some sera of patients with Lyme disease (IgM) and with few sera of patients with autoimmune disease (IgM and IgG). To improve the sensitivity of the ELISA both antigens Wijnberg and Riccio 2 must be employed in the immunoenzymatic assay, since serogroup Australis must be considered as a new emerging serogroup causing human leptospirosis in our country. AD - Istituto di Microbiologia, Universita degli Studi, Trieste, Italy. PMID- 1426167 SO - Eur J Epidemiol 1992 Sep;8(5):677-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 93016756 AU - Merien F AU - Amouriaux P AU - Perolat P AU - Baranton G AU - Saint Girons I TI - Polymerase chain reaction for detection of Leptospira spp. in clinical samples. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Base Sequence MH - Blood/microbiology MH - Blotting, Southern MH - Digoxigenin MH - DNA, Ribosomal/*isolation & purification MH - Female MH - Human MH - Leptospira interrogans/*isolation & purification MH - Male MH - Mice MH - Middle Age MH - Molecular Sequence Data MH - Nucleic Acid Hybridization MH - Polymerase Chain Reaction/*methods MH - RNA, Ribosomal, 16S/*genetics MH - Sensitivity and Specificity MH - Species Specificity MH - Spirochaetales/genetics MH - Support, Non-U.S. Gov't MH - Urine/microbiology MH - Weil's Disease/*diagnosis/genetics RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Ribosomal, 16S) RN - 1672-46-4 (Digoxigenin) PT - JOURNAL ARTICLE DA - 921030 DP - 1992 Sep IS - 0095-1137 TA - J Clin Microbiol PG - 2219-24 SB - M CY - UNITED STATES IP - 9 VI - 30 JC - HSH AA - Author EM - 9301 AB - A sensitive assay for Leptospira spp., the causative agent of leptospirosis, was developed on the basis of the polymerase chain reaction (PCR). A 331-bp sequence from the Leptospira interrogans serovar canicola rrs (16S) gene was amplified, and the PCR products were analyzed by DNA-DNA hybridization by using a 289-bp fragment internal to the amplified DNA. Specific PCR products also were obtained with DNA from the closely related nonpathogenic Leptospira biflexa but not with DNA from other spirochetes, such as Borrelia burgdorferi, Borrelia hermsii, Treponema denticola, Treponema pallidum, Spirochaeta aurantia, or more distant organisms such as Escherichia coli, Staphylococcus aureus, Mycobacterium tuberculosis, and Proteus mirabilis. The assay was able to detect as few as 10 bacteria. Leptospira DNA was detected in urine from experimentally infected mice. In addition, the test was found to be suitable for diagnosing leptospirosis in humans. Cerebrospinal fluid and urine from patients with leptospirosis were positive, whereas samples from control uninfected patients were negative. AD - Unite de Bacteriologie Moleculaire et Medicale, Institut Pasteur, Paris, France. PMID- 1400983 SO - J Clin Microbiol 1992 Sep;30(9):2219-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 94098159 AU - Uip DE AU - Amato Neto V AU - Duarte MS TI - [The early diagnosis of leptospirosis by demonstrating antigens via an immunohistochemical exam of the hamstring muscle] LA - Por MH - Adolescence MH - Adult MH - Aged MH - Antigens, Bacterial/*metabolism MH - Biopsy MH - English Abstract MH - Female MH - Human MH - Immunohistochemistry MH - Leptospira interrogans/*immunology MH - Male MH - Middle Age MH - Muscles/*metabolism/pathology MH - Myositis/diagnosis/pathology MH - Time Factors MH - Weil's Disease/*diagnosis/pathology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 940203 DP - 1992 Sep-Oct IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 375-81 CY - BRAZIL IP - 5 VI - 34 JC - S9D AA - Author EM - 9404 AB - Establishing an early and certain diagnosis of leptospirosis has been a difficult task. So, we analysed the histopathological alterations of the gastrocnemius muscle, and studied, for the first time, the usefulness of the immune histochemical method of peroxidase- antiperoxidase for the demonstration of the spirochete and of its products in this tissue. Histopathological observations have shown a picture of myositis, characterized by interstitial inflammatory infiltrate and necrotic-degenerative abnormalities of muscle fibers. The lesions were considered minimal in 69.45% of the patients, moderate in 19.45%, severe in 5.55% and absent in the remaining. On the other hand, the immune histochemical method identified the etiology in 94.45% what was considered very expressive. AD - Divisao de Clinica de Molestias Infecciosas e Parasitarias, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo. PMID- 1342098 TT - Diagnostico precoce da leptospirose por demonstracao de antigenos atraves de exame imuno-histoquimico em musculo da panturrilha. EA - A SO - Rev Inst Med Trop Sao Paulo 1992 Sep-Oct;34(5):375-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 94084184 AU - Cerny A AU - Ettlin D AU - Betschen K AU - Berchtold E AU - Hottinger S AU - Neftel KA TI - Weil's disease after a rat bite. LA - Eng MH - Adult MH - Animal MH - Bites and Stings/*complications MH - Case Report MH - Female MH - Human MH - Leptospirosis/*transmission MH - Male MH - *Rats MH - *Zoonoses PT - JOURNAL ARTICLE DA - 940124 DP - 1992 Sep IS - 1165-0478 TA - Eur J Med PG - 315-6 SB - M CY - FRANCE IP - 5 VI - 1 JC - BYE EM - 9403 AD - Medizinische und Chirurgische Klinik, Zieglerspital, Bern, Switzerland. PMID- 1341617 SO - Eur J Med 1992 Sep;1(5):315-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 93279671 AU - Zhang Y AU - Dai B TI - [Marking and detection of DNA of leptospires in the dot-blot and situ hybridization with digoxigenin-labelled probes] LA - Chi MH - Animal MH - Digoxigenin MH - *DNA Probes MH - DNA, Bacterial/*analysis MH - English Abstract MH - Guinea Pigs MH - Human MH - Immunoblotting MH - In Situ Hybridization MH - Leptospira interrogans/classification/*isolation & purification MH - Male MH - Support, Non-U.S. Gov't RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) RN - 1672-46-4 (Digoxigenin) PT - JOURNAL ARTICLE DA - 930707 DP - 1992 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 353-7 CY - CHINA IP - 4 VI - 23 JC - GEB AA - Author EM - 9309 AB - DNA of Leptospira interrogans sv. lai strain 017 was labelled with digoxigenin or alpha 32P or biotin and used as probes to detect DNA of leptospires. Probes labelled with digoxigenin were able to detect 0.1-1 pg of homologous DNA and 10(2) of L. interrogans sv. lai strain 017. Probes alpha 32P and biotin detected 1 pg and 10 pg of homologous DNA and 10(3), 5 x 10(3) of L. interrogans sv. lai strain 017 respectively. These three probes couldn't detect L. biflexa sv. patoc strain Patoc I, L. illini strain 3055, Escherichia coli. Bacillus aerogenes capsulalus, Salmonella anatis, K-DNA of Leishmania, and of human WBC. Comparison of digoxigenin-, alpha 32P- and Biotin-labelled probes in the dot-blot hybridization assay on different serogroup sv. of leptospires revealed that digoxigenin-labelled probes were more sensitive than alpha 32P and biotin-labelled probes. The results indicate that digoxigenin-labelled probes DNA can be used for detection of leptospires in field and clinic. We also report procedures in situ hybridization with leptospira in tissues smear and plasma sediment of an experimentally infected guinea pig. It offers the advantage of recognizable of leptospiral morphology in combination with a hybridization signals. The results indicate that digoxigenin-labelled DNA probes of 017 strain might provide tool for routine diagnosis and classification in cases of leptospiral interrogans infection. PMID- 1304535 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992 Sep;23(4):353-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 93233557 AU - Ambalov IuM AU - Barinova KhG AU - Usatkin AV AU - Dotsenko VA TI - [The use of Wald's sequential alternative analysis for the differential diagnosis of trichinelliasis and leptospirosis in the initial period of the disease] LA - Rus MH - Adult MH - Case Report MH - Comparative Study MH - Diagnosis, Differential MH - Diagnostic Errors MH - English Abstract MH - Human MH - Incidence MH - Leptospirosis/*diagnosis/epidemiology MH - Male MH - Statistics/methods MH - Time Factors MH - Trichinosis/*diagnosis/epidemiology PT - JOURNAL ARTICLE DA - 930514 DP - 1992 Sep-Dec IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 21-3 CY - RUSSIA IP - 5-6 JC - M72 EM - 9307 PMID- 1299754 TT - Ispol'zovanie posledovatel'nogo al'ternativnogo analiza Val'da dlia differentsial'noi diagnostiki trikhinelleza i leptospiroza v nachal'nom periode bolezni. EA - A SO - Med Parazitol (Mosk) 1992 Sep-Dec;(5-6):21-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 93224108 AU - Zhang Y AU - Dai B TI - [Detection of leptospiral DNA in the serum of 175 patients with early leptospirosis by polymerase chain reaction] LA - Chi MH - Animal MH - Base Sequence MH - DNA, Bacterial/*analysis MH - English Abstract MH - Genes, Bacterial MH - Guinea Pigs MH - Leptospira interrogans/immunology/*isolation & purification MH - Male MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - RNA, Ribosomal, 23S/genetics MH - Weil's Disease/*diagnosis RN - 0 (DNA, Bacterial) RN - 0 (RNA, Ribosomal, 23S) PT - JOURNAL ARTICLE DA - 930513 DP - 1992 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 256-60 CY - CHINA IP - 3 VI - 23 JC - GEB AA - Author EM - 9307 AB - We have developed a sensitive assay for leptospira, using the polymerase chain reaction (PCR). On the basis of the published nucleotides sequence of 23S rRNA gene from Leptospira interrogans serovar canicola strain Moulton, primers were chosen to produce an amplified fragment of 123 bp. Primer A: 5'GAT CTA ATT CGC TGT AGC AGG3' and primer B: 5'ACT TTC ACC CTC TAT GGT CGG3' Eight different svs. of Leptospira interrogans could all be detected by PCR, but the DNAs from L. biflexa. Leptonema bacteria, virus and human could not produce the specific amplified fragment. The assay detected approximately 10 fg of purified leptospiral DNA and 1 microliter serum of experimental animal. Positive results were obtained from simulated positive samples containing a single organism leptospiral DNA. The diagnostic test (proved by "gold standards": Clinical diagnosis; blood culture and MAT) showed that the sensitivity was 92.00%; the specificity 94.35%; the accuracy 92.54%; the positive predictive value 98.17%; the negative predictive value 78.13%; the positive likelihood ratio 16.25; and the negative likelihood ratio 0.0848. The diagnosis of early leptospirosis by using PCR may become a significant addition to diagnostic means. PMID- 1298712 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992 Sep;23(3):256-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 93224107 AU - Bao L AU - Dai B AU - Gravekamp C AU - Hartskeerl R AU - Terpstra W TI - [The detection and analysis of leptospiral DNA in patients' serum of early leptospirosis by polymerase chain reaction and DNA hybridization with digoxigenin-AMPPD] LA - Chi MH - Adamantane/*analogs & derivatives MH - Blotting, Southern MH - *Digoxigenin MH - DNA Probes MH - DNA, Bacterial/*analysis MH - English Abstract MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*diagnosis MH - Nucleic Acid Hybridization MH - *Polymerase Chain Reaction MH - Support, Non-U.S. Gov't RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) RN - 122341-56-4 (3-(2'-spiroadamantane)-4-methoxy-4-(3''- phosphoryloxy)phenyl-1,2-dioxetane) RN - 1672-46-4 (Digoxigenin) RN - 281-23-2 (Adamantane) PT - JOURNAL ARTICLE DA - 930513 DP - 1992 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 251-5 CY - CHINA IP - 3 VI - 23 JC - GEB AA - Author EM - 9307 AB - We have detected and analysed the leptospiral DNA in serum of patients with early Leptospirosis from the epidemic area of China by PCR and DNA hybridization with Digoxigenin (Dig)-3-(2'-Spiroadamantane)-4-methoxy-4- (3"-phosphoryloxy)- phenyl-1,2-dioxetane (AMPPD) to develop a sensitive, specific and reliable technique for the early diagnosis of leptospirosis, and full satisfactory results have obtained. Fourteen serum specimens from patients with leptospirosis proven by blood culture and serological test were prepared according to Boom's methods for PCR test, and oligonucleotide primers, named G1 G2, were obtained from a genomic library of leptospira interrogans. PCR amplification with serum specimens was performed. Each cycle of amplification consisted of denaturation at 94 degrees C for 1 min, annealing at 55 degrees C for 1 min and elongation at 72 degrees C for 2 min. Each sample was subjected to 32 cycles. The amplified DNA were separated by electrophoresis with 2% agarose gel and hybridized with the homologous DNA probe labelling with Dig-AMPPD by means of Southern blotting. All of 14 samples revealed the presence of leptospira and the strong signals were visualized with homologous DNA probe hybridization by Southern blotting. Negative and positive controls appeared correctly. The DNA fragment generated from PCR amplification homologically hybridized with the DNA of 16 strains which are from Yasudas' genomic species and represent the different genomic groups of leptospires. The single recognized band (about 400 bps) from 6 out of the 16 strains has come out which are representative of the principal strains in Sichuan, China.(ABSTRACT TRUNCATED AT 250 WORDS) AD - WHO/FAO Collabrative and Research Centre of Leptospirosis, Royal Tropical Institute, The Netherlands. PMID- 1298711 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992 Sep;23(3):251-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 93279670 AU - Zhang M AU - Dai B TI - [The production and identification of partial serogroup--specific monoclonal antibodies against leptospires hebdomadis serogroup] LA - Chi MH - Animal MH - Antibodies, Bacterial/immunology MH - Antibodies, Monoclonal/biosynthesis MH - English Abstract MH - Epitopes MH - Hybridomas/immunology MH - Leptospira/*classification MH - Leptospira interrogans/*classification MH - Mice MH - Mice, Inbred BALB C MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 930707 DP - 1992 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 349-52 CY - CHINA IP - 4 VI - 23 JC - GEB AA - Author EM - 9309 AB - Hebdomadis is one of the major serogroups found in China. In Sichuan, this serogroup appears to have a close relationship with local outbreak of leptospirosis. BALB/c mice were immunized intrasplenically with outer envelope of serogroup Hendomadis serovar hebdomadis strain 245. Spleen cells were fused with SP2/0 myeloma cells, two monoclonal antibodies Af2 and Bb2 were produced by hybridoma technique. McAb Af2 and McAb Bb2 were identified to be IgG1 and IgG3 by immunodiffusion respectively. Specificities of these two McAbs were determined by MAT; both reacted to 8 serovars (hebdomadis, nona, kambale, kremastos, worsfoldi, jules, maruborincana) of Hebdomadis serogroup. The agglutination titres of McAb Af2 and McAb Bb2 were 1:640-1:2,500,000 and 1:320-1:2,500,000, respectively. The two McAbs did not agglutinate with serovar kabura of Hebdomadis serogroup, they did not agglutinate with 11 serovars of Sejroe serogroup, 4 serovars of Mini serogroup, 18 representive serovars of L. interrogans in 18 serogroups, L. biflexa strain Patoc I and Leptonema illini. So it was found that McAb Af2 and McAb Bb2 showed partial serogroup specificity for Hebdomadis by agglutination. PMID- 1284791 CU - 95 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992 Sep;23(4):349-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 93032714 AU - Norgard B AU - Hansen LM AU - Jensen BF TI - [Leptospirosis. A disease with non-specific initial symptoms] LA - Dan MH - Adult MH - Case Report MH - Diagnosis, Differential MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis/drug therapy MH - Male MH - Penicillins/therapeutic use RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 921118 DP - 1992 Aug 31 IS - 0041-5782 TA - Ugeskr Laeger PG - 2438-9 CY - DENMARK IP - 36 VI - 154 JC - WM8 AA - Author EM - 9301 AB - A case of leptospirosis in a young fish-farm worker is described. Early penicillin therapy was initiated solely on the clinical suspicion of the disease. The importance of recognition of the disease is emphasized together with early institution of penicillin therapy and effective eradication of vermin. AD - Hobro Sygehus, Medicinsk afdeling. PMID- 1413166 TT - Leptospirosis. En sygdom med uspecifikke debutsymptomer. EA - A SO - Ugeskr Laeger 1992 Aug 31;154(36):2438-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 93069905 AU - Rocha T AU - Vieira RP TI - Experimental infection of pregnant gilts with Leptospira interrogans serovar mozdok. LA - Eng MH - Abortion, Veterinary/etiology MH - Agglutination Tests/veterinary MH - Animal MH - Female MH - *Leptospira interrogans MH - Leptospirosis/complications/microbiology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/*veterinary MH - Species Specificity MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 921127 DP - 1992 Aug 29 IS - 0042-4900 TA - Vet Rec PG - 197-9 SB - M CY - ENGLAND IP - 9 VI - 131 JC - XBS AA - Author EM - 9302 AB - Three pregnant gilts were experimentally infected with leptospires of the serovar mozdok, isolated from an aborted pig fetus from a Portuguese pig farm with abortion problems. All the gilts aborted dead or dying piglets on days 105 or 106 of pregnancy. Serovar mozdok was isolated from 12 of the 22 piglets in the three litters. Histological examination of the livers and kidneys of the gilts at the end of the experiment revealed evidence of disease, and leptospires were isolated from their kidneys. Their serological responses up to 42 days after inoculation were monitored by means of a microscopic agglutination test, using 21 antigens from 18 serogroups. Cross reactions to heterologous antigens belonging to the Grippotyphosa, Australis, Icterohaemorrhagiae and Cynopteri groups were observed in all of them. AD - Bacteriology Department, Laboratorio Nacional de Investigacao Veterinaria, Estrada de Benfica, Lisbon, Portugal. PMID- 1441176 SO - Vet Rec 1992 Aug 29;131(9):197-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 92397493 AU - Little TW AU - Hathaway SC AU - Broughton ES AU - Seawright D TI - Control of Leptospira hardjo infection in beef cattle by whole-herd vaccination. LA - Eng MH - Age Factors MH - Animal MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Female MH - Leptospira/*immunology MH - Leptospirosis/prevention & control/*veterinary MH - Scotland MH - Time Factors MH - Vaccination/*veterinary RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 921009 DP - 1992 Aug 1 IS - 0042-4900 TA - Vet Rec PG - 90-2 SB - M CY - ENGLAND IP - 5 VI - 131 JC - XBS AA - Author EM - 9212 AB - A whole-herd vaccination programme to control Leptospira hardjo infection was applied to a closed herd of approximately 800 beef cattle on the island of Luing in Scotland. An experimental vaccine was produced and the herd was vaccinated annually for five years. Progress was monitored by means of a catalytic model using data for age-specific serological prevalences and geometric mean titres. Any cattle introduced to the herd were subject to antibiotic treatment and quarantine, and at the end of the trial the whole herd was treated prophylactically with antibiotics to minimise the risk of residual infection. There was a progressive right shift in age-specific serological prevalences, and by the end of the trial all young stock entering the breeding herd were seronegative. The age-specific geometric mean titres demonstrated the cessation of an endemic cycle of hardjo infection in the herd. Birth cohort analysis supported the serological evidence of a high level of control, and bacteriological monitoring at the end of the trial indicated that hardjo had been eliminated from the herd. AD - Ministry of Agriculture, Fisheries and Food Central Veterinary Laboratory, New Haw, Weybridge. PMID- 1523799 SO - Vet Rec 1992 Aug 1;131(5):90-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 92356415 AU - Ribeiro MA AU - Sakata EE AU - Silva MV AU - Camargo ED AU - Vaz AJ AU - De Brito T TI - Antigens involved in the human antibody response to natural infections with Leptospira interrogans serovar copenhageni. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*blood MH - Antigens, Bacterial/*immunology MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - IgG/blood MH - IgM/*blood MH - Immunoblotting MH - Leptospira interrogans/*immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (IgG) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 920910 DP - 1992 Aug IS - 0022-5304 TA - J Trop Med Hyg PG - 239-45 SB - M CY - ENGLAND IP - 4 VI - 95 JC - KAV AA - Author EM - 9211 AB - Serum samples from patients with leptospirosis were screened by the microscopic agglutination test (MAT), ELISA and by immunoblotting. The latter two tests were performed with L. interrogans serovar copenhageni isolated from human blood culture. Immunoblotting with patients' sera revealed antibodies recognizing several leptospiral components in the molecular weight range 14.5-105 kDa of both IgM and IgG response. All patients' serum samples presented IgM antibodies reacting with a diffuse band of mol. wt of 14.8-22 kDa proteinase-K resistant and most reacted with bands of 26.5-28.7, 38-39 and 43-43.5 kDa. The IgG response appeared to be at variance. Examination of sequential serum samples obtained over a 4-8-month period revealed little change in the profile of antigen recognized after the 40th day of infection. Sera from healthy individuals presented IgM antibodies reacting with several leptospiral antigens, but lacked response against those of diffuse band of 14.8-22 kDa. AD - Adolfo Lutz Institute, Secao de Imunologia, Sao Paulo, Brazil. PMID- 1495119 SO - J Trop Med Hyg 1992 Aug;95(4):239-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 93031792 AU - Knorr HL AU - Weber A TI - [Ocular manifestations of selected zoonoses in humans] LA - Ger MH - Animal MH - English Abstract MH - Eye Infections, Bacterial/*epidemiology MH - Eye Infections, Parasitic/*epidemiology MH - Eye Infections, Viral/*epidemiology MH - Human MH - Ornithosis/*epidemiology MH - *Zoonoses PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 921105 DP - 1992 Aug IS - 0303-6286 TA - Tierarztl Prax PG - 347-54 SB - M CY - GERMANY IP - 4 VI - 20 JC - VS4 AA - Author EM - 9301 AB - A report is given on the epidemiology and clinical signs of some selected zoonoses that may be of significance for ocular infections in man: brucellosis, leptospirosis, Lyme borreliosis, lymphocytic choriomeningitis, Newcastle Disease, ornithosis (chlamydiosis), rabies, Streptococcus suis infection, larva migrans ocularis by Toxocara canis or Baylisascaris procyonis, toxoplasmosis and tularemia. AD - Augenklinik mit Poliklinik, Universitat Erlangen-Nurnberg. RF - 42 PMID- 1412422 TT - Uber okulare Manifestationen ausgewahlter Zoonosen beim Menschen. EA - A SO - Tierarztl Prax 1992 Aug;20(4):347-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 93069889 AU - Leonard F AU - Quinn PJ AU - Ellis WA TI - Possible effect of pH on the survival of leptospires in cattle urine [see comments] LA - Eng MH - Ammonia/urine MH - Animal MH - Bacteriuria/microbiology/*veterinary MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Hydrogen-Ion Concentration MH - Hydroxybutyrates/blood MH - Lactates/blood MH - Leptospira/*growth & development MH - Leptospirosis/microbiology/*veterinary RN - 0 (Hydroxybutyrates) RN - 0 (Lactates) RN - 300-85-6 (3-hydroxybutyric acid) RN - 7664-41-7 (Ammonia) PT - JOURNAL ARTICLE DA - 921214 DP - 1992 Jul 18 IS - 0042-4900 TA - Vet Rec PG - 53-4 SB - M CY - ENGLAND IP - 3 VI - 131 JC - XBS EM - 9302 AD - Teagasc, Moorepark Research and Development Division, Fermoy, County Cork. CM - Comment in: Vet Rec 1992 Oct 10;131(15):352 RO - M:LC1 PMID- 1441163 LR - 930407 SO - Vet Rec 1992 Jul 18;131(3):53-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 92355368 AU - Fenger CK AU - Hoffsis GF AU - Kociba GJ TI - Idiopathic immune-mediated hemolytic anemia in a calf. LA - Eng MH - Anemia, Hemolytic, Autoimmune/blood/diagnosis/*veterinary MH - Animal MH - Blood Chemical Analysis/veterinary MH - Case Report MH - Cattle MH - Cattle Diseases/blood/*diagnosis MH - Coombs' Test/veterinary MH - Erythrocytes/pathology MH - Female MH - Osmotic Fragility PT - JOURNAL ARTICLE DA - 920909 DP - 1992 Jul 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 97-9 SB - M CY - UNITED STATES IP - 1 VI - 201 JC - HAV AA - Author EM - 9211 AB - Severe anemia was found in a 4-month-old heifer, which was admitted with a 1-day history of anorexia, signs of depression, and recumbency. A diagnosis of immune-mediated hemolytic anemia (IHA) was made on the basis of a Coomb's titer of 1:128 and decreased resistance to osmotic stress, as determined by an RBC fragility test. Anaplasmosis and leptospirosis were ruled out as possible causes of the IHA. Other causes of hemolytic anemia, including intoxication by copper, water, Brassica spp, or drugs were ruled out. Therefore the IHA was considered idiopathic. Treatment consisted of supportive therapy, oxytetracycline, and dexamethasone. After 60 days of treatment, CBC, Coomb's test result, and RBC fragility were within normal limits. AD - Department of Veterinary Clinical Sciences College of Veterinary Medicine, Ohio State University, Columbus 43210-1089. PMID- 1644656 SO - J Am Vet Med Assoc 1992 Jul 1;201(1):97-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 92332703 AU - Herrmann JL AU - Bellenger E AU - Perolat P AU - Baranton G AU - Saint Girons I TI - Pulsed-field gel electrophoresis of NotI digests of leptospiral DNA: a new rapid method of serovar identification. LA - Eng MH - Animal MH - *Bacterial Typing Techniques MH - Deoxyribonucleases, Type II Site-Specific MH - DNA Fingerprinting MH - DNA, Bacterial/*genetics MH - Electrophoresis, Gel, Pulsed-Field/*methods MH - Human MH - Leptospira/classification/*genetics/isolation & purification MH - Support, Non-U.S. Gov't RN - EC 3.1.21.- (endodeoxyribonuclease NotI) RN - EC 3.1.21.- (endodeoxyribonuclease SgrAI) RN - EC 3.1.21.4 (Deoxyribonucleases, Type II Site-Specific) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 920820 DP - 1992 Jul IS - 0095-1137 TA - J Clin Microbiol PG - 1696-702 SB - M CY - UNITED STATES IP - 7 VI - 30 JC - HSH AA - Author EM - 9210 AB - Fingerprints for 72 reference serovar strains of pathogenic Leptospira spp. were obtained by pulsed-field gel electrophoresis (PFGE) following NotI restriction digests of the chromosome. These strains included the serovar reference strains of serogroups Australis, Ballum, Bataviae, Grippotyphosa, Panama, Pomona, and Pyrogenes. Sixty-four serovars could be identified by a unique NotI restriction profile. The remaining serovars were differentiated by chromosomal digestion with SgrAI. These included four serovars from serogroup Australis, two serovars from serogroup Ballum, and two serovars from serogroup Bataviae. Thirteen of 18 recent clinical isolates identified by microagglutination test and cross-adsorption procedure were correctly typed by PFGE. The results indicate that PFGE, which is considerably more rapid than serology, should be useful for identification and epidemiological studies. AD - Unite de Bacteriologie Moleculaire et Medicale, Institut Pasteur, Paris, France. PMID- 1629323 SO - J Clin Microbiol 1992 Jul;30(7):1696-702 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 92327678 AU - Akkermans JP AU - Kreeft HJ TI - [Results of studies with aborted cattle fetuses] LA - Dut MH - Abortion, Veterinary/*etiology/microbiology MH - Animal MH - Bacteriological Techniques/veterinary MH - Brucella abortus/isolation & purification MH - Cattle MH - Cattle Diseases/*etiology MH - English Abstract MH - Female MH - Fetus/pathology MH - Histological Techniques/veterinary MH - Immunologic Techniques/veterinary MH - Microbiological Techniques/veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 920813 DP - 1992 Jul 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 375-9 SB - M CY - NETHERLANDS IP - 13 VI - 117 JC - VRY AA - Author EM - 9210 AB - The laboratory of the Animal Health Service of South Holland investigated 2410 cases of spontaneous abortion (twins (112) were considered one case). Seventy-eight afterbirths without foetuses were also examined. The aim of the study was not only to find the cause of abortion but also to see whether there was a relation between the results of the different bacteriological, virological and histological tests used. The presence of IgG in the blood of foetuses older than 5 months was also determined. A micro-organism was isolated from 25% of the foetuses. On the basis of results of other tests, it is probable that microbial infection played a role in a further 21% of the abortions. BHV was isolated in 2.5% of the cases. Actinomyces pyogenes was found in 6% of the foetuses and fungi in 3.5%. More infections with Actinomyces pyogenes, Listeria monocytogenes and fungi were observed when the cattle were kept indoors. It is emphasised that both foetuses as well as placental membranes should be examined, and both foetuses of twins. In stable enzooties in the Netherlands, the following infections should be taken into consideration: Brucella abortus, BHV, BVD, Chlamydia psittaci and Leptospira hardjo. The authors stress the need for a more standardised approach to research, the more so because the results could have consequences not only for monitoring activities (checks for Br. abortus) but also for liability. AD - Stichting Gezondheidsdienst voor Dieren in West- en Midden-Nederland, Gouda. PMID- 1626316 TT - De resultaten van onderzoek van geaborteerde rundervruchten. EA - A SO - Tijdschr Diergeneeskd 1992 Jul 1;117(13):375-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [4 protein links] [189 medline neighbors] UI - 92325069 AU - Trueba GA AU - Bolin CA AU - Zuerner RL TI - Characterization of the periplasmic flagellum proteins of Leptospira interrogans. LA - Eng MH - Amino Acid Sequence MH - Bacterial Proteins/*analysis/chemistry MH - Electrophoresis, Gel, Two-Dimensional MH - Flagella/chemistry/immunology/*ultrastructure MH - Leptospira interrogans/chemistry/immunology/*ultrastructure MH - Microscopy, Immunoelectron MH - Molecular Sequence Data RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE DA - 920813 DP - 1992 Jul IS - 0021-9193 TA - J Bacteriol PG - 4761-8 SB - M CY - UNITED STATES IP - 14 VI - 174 JC - HH3 AA - Author EM - 9210 AB - The structure and composition of periplasmic flagella (PF) from Leptospira interrogans serovar pomona type kennewicki were characterized. Electron microscopic observations showed that leptospiral PF were complex structures composed of an 11.3-nm-diameter core surrounded by two sheath layers with 21.5- and 42-nm diameters. Two-dimensional gel electrophoresis of isolated PF showed the presence of seven different proteins ranging in mass from 31.5 to 36 kDa. Rabbit polyclonal and mouse monoclonal antibodies against PF proteins were prepared and were used to localize specific proteins to portions of the PF structure by immunoelectron microscopy. A 34-kDa protein was associated with the 11.3-nm-diameter core filament, while a 36-kDa protein was associated with a PF sheath (21.5-nm-diameter filament). The amino termini of the 34- and 35.5-kDa proteins were homologous to PF core proteins of other spirochetes. The experimental data suggested that L. interrogans PF contains 2 proteins (34 and 35.5 kDa) in the PF core. AD - Leptospirosis/Mycobacteriosis Research Unit, National Animal Disease Center, U.S. Department of Agriculture, Ames, Iowa. PMID- 1624463 SI - GENBANK/A41210 SI - GENBANK/B41210 SO - J Bacteriol 1992 Jul;174(14):4761-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 92395607 AU - Rentko VT AU - Clark N AU - Ross LA AU - Schelling SH TI - Canine leptospirosis. A retrospective study of 17 cases. LA - Eng MH - Animal MH - *Dog Diseases/blood/drug therapy/urine MH - Dogs MH - Female MH - Leptospira interrogans/classification MH - Leptospirosis/blood/drug therapy/urine/*veterinary MH - Male MH - Retrospective Studies MH - Treatment Outcome PT - JOURNAL ARTICLE DA - 921015 DP - 1992 Jul-Aug IS - 0891-6640 TA - J Vet Intern Med PG - 235-44 SB - M CY - UNITED STATES IP - 4 VI - 6 JC - JVG AA - Author EM - 9212 AB - Seventeen dogs were diagnosed with leptospirosis on the basis of clinical findings, laboratory abnormalities, and serology. This article summarizes and characterizes the historical and physical findings, laboratory data, serology, treatment, and outcome of these dogs. All of the dogs had serologic evidence of infection with interrogans serovars pomona and grippotyphosa. These findings are compared with previous reports of canine infection with Leptospira interrogans serovars icteroaemorrhagiae and canicola. The clinical presentation of these dogs did not correspond to the classic description of the disease in dogs in which concurrent renal and hepatic diseases are present. This may be due to infection with different serovars than those previously reported. In addition, this article suggests that canine leptospirosis should be considered in the differential diagnosis of dogs with acute or subacute renal failure. AD - Department of Medicine, School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts 01536. PMID- 1522555 SO - J Vet Intern Med 1992 Jul-Aug;6(4):235-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 92391177 AU - Schonberg A AU - Hahn-Hey B AU - Kampe U AU - Schmidt K AU - Ellis WA TI - The isolation and identification of Leptospira interrogans serovar bratislava from a pig in Germany. LA - Eng MH - Animal MH - Germany MH - Kidney/*microbiology MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 921006 DP - 1992 Jul IS - 0931-1793 TA - Zentralbl Veterinarmed [B] PG - 362-8 CY - GERMANY IP - 5 VI - 39 JC - Y72 AA - Author EM - 9212 AB - During a study on the improvement of selective media for the isolation of leptospires from clinical material, leptospires were isolated from the kidneys of a pig. Test material was cultured in EMJH-medium containing 0.4% rabbit serum and 3 inhibitory substances (Rifampicin 10 micrograms/ml, Amphotericin B 2 micrograms/ml, 5-Fluorouracil 100 micrograms/ml). The cultured leptospira-strain (Berlin 406) was identified to serogroup level using the cross agglutination method and it was further typed to serovar level by MAB's, factor analysis and restriction endonuclease analysis (REA). MAB typing of Berlin 406 gave an agglutination pattern profile typical of serovar bratislava. Factor serum identification clearly identified this strain as serovar bratislava. On REA examination, Berlin 406 gave a profile identical to that of the serovar bratislava type strain Jez Bratislava i.e. genotype B1. This is the first report of a confirmed isolate of Leptospira interrogans serovar bratislava from domestic animals in Germany. There exist a number of possibly important implications as this agent is being incriminated in the cause of clinical disease not only in pigs, but also in horses and dogs in other countries. AD - Institut fur Veterinarmedizin des Bundesgesundheitsamtes, Robert von Ostertag-Institut, Berlin, Germany. PMID- 1519413 SO - Zentralbl Veterinarmed [B] 1992 Jul;39(5):362-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 92385592 AU - Donahue JM AU - Smith BJ AU - Donahoe JK AU - Rigsby CL AU - Tramontin RR AU - Poonacha KB AU - Wilson MA TI - Prevalence and serovars of leptospira involved in equine abortions in central Kentucky during the 1990 foaling season. LA - Eng MH - Abortion, Veterinary/epidemiology/*microbiology MH - Agglutination Tests MH - Animal MH - Bacteriuria/microbiology/veterinary MH - Female MH - Fluorescent Antibody Technique MH - Gastrointestinal Contents/microbiology MH - Gestational Age MH - Horse Diseases/epidemiology/*microbiology MH - Horses MH - Kentucky/epidemiology MH - Kidney/microbiology MH - Leptospira interrogans/*classification/isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Liver/microbiology MH - Placenta/microbiology MH - Pregnancy MH - Prevalence MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 921006 DP - 1992 Jul IS - 1040-6387 TA - J Vet Diagn Invest PG - 279-84 SB - M CY - UNITED STATES IP - 3 VI - 4 JC - A2D AA - Author EM - 9212 AB - A study to determine the prevalence of leptospira-induced abortions in the central Kentucky equine population during the 1990 foaling season and to determine the leptospira serovars responsible was conducted. From July 1, 1989 through June 30, 1990, 32 (4.4%) of 726 submissions (fetuses, stillborn foals, and/or placentas) were diagnosed as leptospirosis by the fluorescent antibody test and/or microscopic agglutination test. Attempts were made to isolate leptospires from the fetal tissues and/or the dam's urine in 31 of these cases. Leptospira interrogans serovar kennewicki was isolated from 11 (35.5%) and serovar grippotyphosa from 2 (6.5%) of the 31 cases. Of 12 cases that were culture negative with serologically positive fetal fluids, 8 had titers against serovar pomona, 1 against bratislava, 1 against grippotyphosa, 1 against hardjo, and 1 against both bratislava and pomona. AD - Department of Veterinary Science, College of Agriculture, University of Kentucky, Lexington 40511. PMID- 1515489 SO - J Vet Diagn Invest 1992 Jul;4(3):279-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 92385095 AU - Cinco M AU - Delneri D AU - Banfi E TI - Immunodominant antigens recognized by the human immune response to infection by organisms of the species Leptospira interrogans serogroup Australis. LA - Eng MH - Antibodies, Bacterial/*immunology MH - Antigens, Bacterial/*immunology MH - Bacterial Proteins/immunology MH - Blotting, Western MH - Human MH - Immunodominant Epitopes/*immunology MH - Leptospira interrogans/classification/*immunology MH - Leptospirosis/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) RN - 0 (Immunodominant Epitopes) PT - JOURNAL ARTICLE DA - 921006 DP - 1992 Jul IS - 0920-8534 TA - FEMS Microbiol Immunol PG - 287-97 SB - M CY - NETHERLANDS IP - 5 VI - 4 JC - AO3 AA - Author EM - 9212 AB - Serum samples from patients infected by organisms of Leptospira interrogans serogroup Australis were tested by Western blot to determine the nature of major antigens that are involved in the immune response. Although there was some patient-to-patient variability, immunodominant genus-specific antigens were found to be proteins of apparent molecular ratio 68, 46 and 35-kDa, and lipopolysaccharide (LPS) sub-units in the 35-14-kDa region. Serogroup epitopes specific for Australis were exclusively saccharides of about 32 and 24 kDa: a serovar-specific antigen for serovar lora was of 38-40 kDa and behaved like a protein. Antibodies to the LPS serogroup-specific antigens and to the 38-40 kDa protein were long-lasting and consequently suggest that these immunodominant epitopes are important in resistance to re- infection. AD - Istituto di Microbiologia, Universita di Trieste, Italy. PMID- 1515158 CU - 92 SO - FEMS Microbiol Immunol 1992 Jul;4(5):287-97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 92381849 AU - Goyal SM AU - Mech LD AU - Nelson ME TI - Prevalence of antibody titers to Leptospira spp. in Minnesota white- tailed deer. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*blood MH - *Deer MH - Female MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Minnesota/epidemiology MH - Prevalence MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 920925 DP - 1992 Jul IS - 0090-3558 TA - J Wildl Dis PG - 445-8 SB - M CY - UNITED STATES IP - 3 VI - 28 JC - KEM AA - Author EM - 9212 AB - Serum samples (n = 204) from 124 white-tailed deer (Odocoileus virginianus) in northeastern Minnesota (USA) were collected from 1984 through 1989 and tested for antibodies to six serovars of Leptospira interrogans (bratislava, canicola, grippotyphosa, hardjo, icterohemorrhagiae, and pomona) using a microtiter agglutination test. Eighty-eight (43%) sera were positive at greater than or equal to 1:100 for antibodies against serovars pomona and/or bratislava; none was positive for any of the other four serovars. None of the 31 sera collected in 1984-85 was positive, whereas all 54 sera collected from 1986 through 1988 had titers of greater than or equal to 1:100. During 1989, only 34 (29%) of 119 sera had titers of greater than or equal to 1:100. Based on these results, we believe there to be wide variability in exposure of Minnesota deer to Leptospira interrogans. AD - Department of Veterinary Diagnostic Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul 55108. PMID- 1512878 SO - J Wildl Dis 1992 Jul;28(3):445-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 93117537 AU - Bergstrom S AU - Garon CF AU - Barbour AG AU - MacDougall J TI - Extrachromosomal elements of spirochetes. LA - Eng MH - Borrelia/genetics/pathogenicity MH - Borrelia burgdorferi/*genetics/pathogenicity MH - Chromosomes, Bacterial/physiology MH - DNA, Circular/genetics MH - In Vitro MH - Plasmids/*genetics MH - Replicon MH - Treponema/*genetics/pathogenicity MH - Virulence RN - 0 (DNA, Circular) RN - 0 (Plasmids) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 930201 DP - 1992 Jul-Aug IS - 0923-2508 TA - Res Microbiol PG - 623-8 SB - M CY - FRANCE IP - 6 VI - 143 JC - R6F AA - Author EM - 9304 AB - The spirochetes include some important pathogenic bacteria, Treponema, Borrelia and Leptospira. The pathogeneses of these spirochetes are very diverse. In an attempt to learn more about the virulence factors among the spirochetes, their genetic organization and capacity have been studied. Structural analysis of the genome in Borrelia has shown that the genome is composed of one linear maxi-chromosome with additional linear minichromosomes as well as several supercoiled circular plasmids. Moreover, the molecular analysis of the terminal ends of one of the linear minichromosomes has revealed that this unique replicon has sequence similarities with poxviruses and particularly the viral agent of African swine fever. The presence of nucleic-acid-containing vesicles and its possible role in mediating DNA transfer between borreliae is an additional, very interesting feature of these organisms. Treponema does not contain any linear DNA, chromosomal or extrachromosomal, however molecular characterization of a 2.6-kb plasmid of Treponema denticola has been performed with the aim of establishing cloning vehicles to study the virulence properties of the genus Treponema. AD - Department of Microbiology, University of Umea, Sweden. RF - 50 PMID- 1475522 SO - Res Microbiol 1992 Jul-Aug;143(6):623-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 93117535 AU - Penn CW AU - Bassford PJ AU - Yelton DB AU - Dunn J AU - Nelson DR AU - Fukunaga M AU - Stanek G TI - Genetic approaches to cell biology and metabolism of spirochetes. LA - Eng MH - Bacterial Outer Membrane Proteins/genetics MH - Borrelia burgdorferi/enzymology/*genetics/immunology/metabolism MH - Electrophoresis, Polyacrylamide Gel MH - Heat-Shock Proteins/immunology MH - In Vitro MH - Leptospira interrogans/genetics MH - RNA, Ribosomal/genetics MH - Spirochaetaceae/enzymology/*genetics/immunology/metabolism MH - Treponema pallidum/genetics RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Heat-Shock Proteins) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 930201 DP - 1992 Jul-Aug IS - 0923-2508 TA - Res Microbiol PG - 605-13 SB - M CY - FRANCE IP - 6 VI - 143 JC - R6F AA - Author EM - 9304 AB - Genetic analysis and methodology have only comparatively recently been applied to the study of spirochetes. Although genetic transfer procedures for spirochetes are not widely available, there are several examples of progress in genetic analysis of spirochetes by other approaches. Some examples of these approaches are the following. 1) Genes for synthetic pathways in Treponema and Leptospira have been cloned by complementation of Escherichia coli serving as plasmid hosts. 2) The OspA protein of Borrelia burgdorferi has been overexpressed in E. coli without the signal peptide; the recombinant product has been suitable for circular dichroism as well as other biochemical analyses. 3) The heat shock proteins of B. burgdorferi are homologous to heat shock proteins of E. coli. 4) Enzyme activity profiles of B. burgdorferi and other spirochetes show strain heterogeneity and also indicate which biosynthetic and enzymatic activities are conserved within different spirochetes. 5) The gene organization of rRNA genes have revealed differences between spirochetes and other types of bacteria. AD - School of Biological Sciences, University of Birmingham, UK. RF - 25 PMID- 1475521 SO - Res Microbiol 1992 Jul-Aug;143(6):605-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 93117536 AU - Saint Girons I AU - Norris SJ AU - Gobel U AU - Meyer J AU - Walker EM AU - Zuerner R TI - Genome structure of spirochetes. LA - Eng MH - Borrelia burgdorferi/classification/*genetics MH - DNA, Circular/genetics MH - In Vitro MH - Leptospira interrogans/*genetics MH - Polymorphism, Restriction Fragment Length MH - Restriction Mapping MH - RNA, Ribosomal/analysis MH - Treponema pallidum/*genetics RN - 0 (DNA, Circular) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 930201 DP - 1992 Jul-Aug IS - 0923-2508 TA - Res Microbiol PG - 615-21 SB - M CY - FRANCE IP - 6 VI - 143 JC - R6F AA - Author EM - 9304 AB - The genome structures of several pathogenic spirochetes have recently been determined. The genomes of Borrelia species consist of a linear chromosome of approximately one million base pairs (Mb) and various linear and circular plasmids. Analysis of restriction fragment length polymorphisms and 16S ribosomal RNA sequence data indicate the division of Borrelia burgdorferi into at least three distinct genetic groups. Leptospira interrogans has a circular chromosome 5 Mb in size and a 0.35 Mb extrachromosomal element. Repetitive sequence elements similar to insertion sequences have been identified in the Leptospira interrogans genome. The chromosome of Treponema pallidum subsp. pallidum is circular and has a size of approximately one Mb. Genetic studies conducted to date indicate that B. burgdorferi and L. interrogans have a high degree of genetic diversity, whereas remarkably few genetic differences have been observed among the pathogenic Treponema. Knowledge of the genomic structure of these organisms will serve as a basis for future genetic studies. AD - Unite de Bacteriologie Moleculaire et Medicale, Institut Pasteur, Paris, France. RF - 24 PMID- 1362002 CU - 94 SO - Res Microbiol 1992 Jul-Aug;143(6):615-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 93021802 AU - Tamai T AU - Shinozaki F AU - Kobayashi Y TI - [The application of DNA studies to leptospirosis] LA - Jpn MH - DNA, Bacterial/*analysis MH - Human MH - Leptospira/genetics/*isolation & purification MH - Leptospirosis/*diagnosis MH - Nucleic Acid Hybridization MH - Polymerase Chain Reaction MH - Polymorphism, Restriction Fragment Length MH - Serotyping RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 921120 DP - 1992 Jul IS - 0047-1852 TA - Nippon Rinsho PG - 427-32 CY - JAPAN VI - 50 Suppl JC - KIM EM - 9301 AD - First Department of Internal Medicine, School of Medicine, Ehime University. RF - 19 PMID- 1357212 CU - 94 SO - Nippon Rinsho 1992 Jul;50 Suppl:427-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 94098155 AU - Camargo ED AU - da Silva MV AU - Batista L AU - Vaz AJ AU - Sakata EE TI - [An evaluation of the ELISA-IgM test in the early diagnosis of human leptospirosis] LA - Por MH - Adolescence MH - Adult MH - Antibodies, Bacterial/*blood MH - Child MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Evaluation Studies MH - Female MH - Human MH - IgM/*blood MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Male MH - Middle Age MH - Weil's Disease/*diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 940202 DP - 1992 Jul-Aug IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 355-7 CY - BRAZIL IP - 4 VI - 34 JC - S9D AA - Author EM - 9404 AB - Thirty-seven sera samples from patients with leptospirosis icterohaemorrhagic form were studied with a time interval of 2 to 12 days between the beginning of the symptoms and the collection blood samples. It was isolated leptospira of 5 patients' hemocultures (13.5%) and from 4 of these the etiological agent pertained to the serogroup Icterohaemorrhagiae serovar copenhageni. Thirty-five of them (94.6%), including the four patients whose the etiological agent was isolated, showed reactivity in the enzyme linked immunosorbent (ELISA) IgM test. By this way, it was demonstrated that this test is important for a rapid diagnosis of human leptospirosis, even in the beginning of the disease, when there is still leptospiraemic phase. AD - Instituto Adolfo Lutz, Sao Paulo, Brasil. PMID- 1342094 TT - Avaliacao do teste ELISA-IgM no diagnostico precoce da leptospirose humana. EA - A SO - Rev Inst Med Trop Sao Paulo 1992 Jul-Aug;34(4):355-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 92395296 AU - Gray JJ AU - Caldwell J AU - Sillis M TI - The rapid serological diagnosis of infectious mononucleosis. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Antibodies, Heterophile/*blood/immunology MH - Antibodies, Viral/*blood MH - Antigens, Viral/blood/immunology/isolation & purification MH - Child, Preschool MH - Comparative Study MH - False Positive Reactions MH - Fluorescent Antibody Technique MH - Herpesvirus 4, Human/*immunology MH - Human MH - Infectious Mononucleosis/*diagnosis/immunology MH - Latex Fixation Tests MH - Middle Age MH - Sensitivity and Specificity RN - 0 (Antibodies, Heterophile) RN - 0 (Antibodies, Viral) RN - 0 (Antigens, Viral) RN - 0 (Epstein-Barr viral capsid antigen) PT - JOURNAL ARTICLE DA - 921015 DP - 1992 Jul IS - 0163-4453 TA - J Infect PG - 39-46 SB - M CY - ENGLAND IP - 1 VI - 25 JC - IG9 AA - Author EM - 9212 AB - A total of 121 samples of serum collected from 101 patients was tested to determine the sensitivity and specificity of a commercial latex agglutination test for detecting infectious mononucleosis heterophile antibody, a commercial immunofluorescence test for detecting antibody to Epstein-Barr virus capsid antigen and a rapid enzyme immunoassay for detecting antibody to Epstein-Barr virus nuclear antigen. Although the Epstein-Barr virus capsid antigen IgM indirect immunofluorescence test proved to be the most sensitive, false-positive reactions were seen when samples collected from patients with cytomegalovirus, hepatitis A virus, parvovirus and leptospira infection were tested. False-positive reactions were also seen with samples containing rheumatoid factor. AD - Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, U.K. PMID- 1326013 CU - 93 SO - J Infect 1992 Jul;25(1):39-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 92328448 AU - Everard CO AU - Everard JD TI - Mongoose rabies in the Caribbean. LA - Eng MH - Animal MH - *Mongoose MH - Rabies/epidemiology/prevention & control/*veterinary MH - West Indies/epidemiology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 920813 DP - 1992 Jun 16 IS - 0077-8923 TA - Ann N Y Acad Sci PG - 356-66 SB - M SB - X CY - UNITED STATES VI - 653 JC - 5NM AA - Author EM - 9210 AB - Mongooses (Herpestes auropunctatus) have been introduced into most of the larger Caribbean islands, some notable exceptions being Dominica, Tobago, and Montserrat. Rabies in Caribbean mongooses is present in Puerto Rico, Cuba, the Dominican Republic (and presumably Haiti), and Grenada. Bat rabies is known on Cuba, Grenada, and Trinidad, although mongooses found on Trinidad are free of the disease. None of the other islands is known to have rabies, although it could be present in sequestered bat populations. All reported case numbers of mongoose rabies in the Caribbean are underestimates, and available information is at best incomplete and at times fragmentary. Nevertheless, data are presented from the four affected islands. Mongoose reduction campaigns have been undertaken on Cuba and Grenada. In Cuba strychnine sulfate inoculated into labeled eggs is used, whereas in Grenada sodium fluoroacetate (1080) has been used in boiled cowhide baits. Mongoose poisoning is unsatisfactory and ineffective in the long-term. Because many mongooses naturally exposed to rabies virus develop serum neutralizing antibodies and are considered to be immunized, possibly for life, vaccination in the wild has been under consideration since the mid-1970s. Early attempts to produce a pill coated with ERA vaccine for enteric absorption in mongooses were not very successful, but new modified vaccines and recombinant techniques hold considerable promise. AD - Leptospira Laboratory, St. Michael, Barbados. RF - 34 PMID- 1626884 SO - Ann N Y Acad Sci 1992 Jun 16;653:356-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 92328423 AU - Ahl AS AU - Miller DA AU - Bartlett PC TI - Leptospira serology in small ruminants on St. Croix, U.S. Virgin Islands. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*blood MH - Goat Diseases/*epidemiology MH - Goats MH - Leptospira interrogans/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Prevalence MH - Sheep MH - Sheep Diseases/*epidemiology MH - Virgin Islands of the United States/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 920813 DP - 1992 Jun 16 IS - 0077-8923 TA - Ann N Y Acad Sci PG - 168-71 SB - M SB - X CY - UNITED STATES VI - 653 JC - 5NM AA - Author EM - 9210 AB - A serological survey of 16 serovars of Leptospira interrogans, previously reported in tropical small ruminants, was undertaken to determine the serovars involved and the prevalence of these antibodies in sheep and goats on St. Croix, U. S. Virgin Islands (USVI). Seven of eight goat herds (108 animals) had at least two seropositive animals in each herd with an individual animal seroprevalence of 26%. The 53 sheep tested (one flock only) showed a 32% seroprevalence. Antibodies against seven serovars were detected in goats (autumnalis, ballum, bataviae, bratislava, canicola, icterohemorrhagiae, and pyrogenes). In addition, hardjo antibodies were detected in sheep. Serovar autumnalis accounted for about 30% of seropositive animals in each species. Many animals showed titers against more than one serovar. The number of seropositive animals suggests Leptospira may be a factor in the health of small ruminants on St. Croix. AD - Risk Analysis Section, United States Department of Agriculture, Animal and Plant Health Inspection Service, Hyattsville, Maryland 20782. PMID- 1626866 SO - Ann N Y Acad Sci 1992 Jun 16;653:168-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 93018315 AU - Kadoya S TI - [A case of leptospirosis manifesting acute pancreatitis and cholecystitis] LA - Jpn MH - Acute Disease MH - Aged MH - Antibodies, Bacterial/analysis MH - Case Report MH - Cholecystitis/diagnosis/*microbiology MH - Diagnosis, Differential MH - Human MH - Leptospira/immunology MH - *Leptospirosis MH - Male MH - Pancreatitis/diagnosis/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 921026 DP - 1992 Jun 10 IS - 0021-5384 TA - Nippon Naika Gakkai Zasshi PG - 911-2 CY - JAPAN IP - 6 VI - 81 JC - IPZ EM - 9301 PMID- 1402246 SO - Nippon Naika Gakkai Zasshi 1992 Jun 10;81(6):911-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 92349373 AU - Weeks DC TI - Leptospirosis--a cause for concern? [letter; comment] LA - Eng MH - Borneo MH - Diagnosis, Differential MH - Heat Exhaustion/diagnosis MH - Human MH - Leptospirosis/diagnosis/*etiology MH - Male MH - *Military Personnel MH - Risk Factors PT - COMMENT PT - LETTER DA - 920901 DP - 1992 Jun IS - 0035-8665 TA - J R Army Med Corps PG - 102-3 SB - M CY - ENGLAND IP - 2 VI - 138 JC - JV6 EM - 9211 CM - Comment on: J R Army Med Corps 1992 Feb;138(1):40-2 RO - M:LC1 PMID- 1640411 LR - 930111 SO - J R Army Med Corps 1992 Jun;138(2):102-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 92349372 AU - Green AD AU - Busuttil W TI - Leptospirosis--a cause for concern? [letter; comment] LA - Eng MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Heat Exhaustion/diagnosis MH - Human MH - Italy MH - Leptospira interrogans MH - Male MH - *Military Personnel MH - Weil's Disease/*diagnosis PT - COMMENT PT - LETTER DA - 920901 DP - 1992 Jun IS - 0035-8665 TA - J R Army Med Corps PG - 102 SB - M CY - ENGLAND IP - 2 VI - 138 JC - JV6 EM - 9211 CM - Comment on: J R Army Med Corps 1992 Feb;138(1):40-2 RO - M:LC1 PMID- 1640410 LR - 930111 SO - J R Army Med Corps 1992 Jun;138(2):102 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 92336552 AU - Parma AE AU - Cerone SI AU - Sansinanea SA TI - Biochemical analysis by SDS-PAGE and western blotting of the antigenic relationship between Leptospira and equine ocular tissues. LA - Eng MH - Animal MH - Antibodies, Bacterial/immunology MH - Antigens, Bacterial/*immunology MH - Blotting, Western/*veterinary MH - Cornea/*immunology MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel/*veterinary MH - Horse Diseases/*immunology MH - Horses MH - Lens, Crystalline/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/*veterinary MH - Support, Non-U.S. Gov't MH - Uveitis/veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 920820 DP - 1992 Jun IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 179-85 SB - M CY - NETHERLANDS IP - 1-2 VI - 33 JC - XCB AA - Author EM - 9210 AB - The antigenic relationship between Leptospira interrogans, equine cornea and lens was previously noted in our studies. Serum antibodies from horses inoculated with serovars wolffi, pomona, icterohaemorrhagiae, and tarassovi, were able to bind to five antigenic fractions from both cornea and lens, as demonstrated by immunoblotting. These antigens seem to be made up of protein and carbohydrates. After treatment with periodate for cleavage of glycoside ring structures, those fractions kept their condition of target for anti-Leptospira antibodies. Nevertheless, all fractions lost that condition after being subjected to peptide hydrolysis. AD - Laboratorio de Inmunoquimica y Biotecnologia, Facultad Ciencias Veterinarias, Universidad Nacional del Centro, Tandil, Argentina. PMID- 1632080 SO - Vet Immunol Immunopathol 1992 Jun;33(1-2):179-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 92318881 AU - Shaw RD TI - Kayaking as a risk factor for leptospirosis. LA - Eng MH - Adult MH - Case Report MH - Hospitalization MH - Human MH - *Immersion MH - Leptospira/*isolation & purification MH - Leptospirosis/*etiology/microbiology MH - Male MH - Missouri MH - Sewage/adverse effects MH - *Sports MH - United States MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 920806 DP - 1992 Jun IS - 0026-6620 TA - Mo Med PG - 354-7 CY - UNITED STATES IP - 6 VI - 89 JC - NEW AA - Author EM - 9210 AB - Leptospirosis is a common zoonosis present throughout Missouri. Previously regarded as an occupational illness of farmers and sewer workers, it is now primarily acquired from exposure to water polluted with the bacteria Leptospira. We present a case report of leptospirosis acquired through kayaking and review both the disease and the risk factor associated with kayaking. AD - Family Practice Department, Ozarks Medical Center, West Plains, MO. PMID- 1620089 SO - Mo Med 1992 Jun;89(6):354-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 93084110 AU - Zhang Y AU - Dai B TI - [Detection of leptospira by dot blot hybridization with photobiotin- and 32P-labelled DNA] LA - Chi MH - Affinity Labels MH - Azides/*diagnostic use MH - Biotin/*analogs & derivatives/diagnostic use MH - DNA Probes MH - DNA, Bacterial/*analysis MH - English Abstract MH - Immunoblotting MH - Leptospira interrogans/*isolation & purification MH - Nucleic Acid Hybridization MH - Phosphorus Radioisotopes/diagnostic use MH - Support, Non-U.S. Gov't RN - 0 (Affinity Labels) RN - 0 (Azides) RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) RN - 0 (Phosphorus Radioisotopes) RN - 58-85-5 (Biotin) RN - 96087-37-5 (photobiotin) PT - JOURNAL ARTICLE DA - 930107 DP - 1992 Jun IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 130-2 CY - CHINA IP - 2 VI - 23 JC - GEB AA - Author EM - 9303 AB - Photobiotin- and 32P-labelled DNA probes of L. interrogans sv. lai strain 017 were produced and the DNA and leptospires were dotted on the NC filter and hybridized. The results showed that photobiotin and 32P- labelled DNA probes could detect DNAs of homology. The smallest amount of DNA that could be detected with the probes were 5pg and 1pg, and the smallest numbers of pathogenic leptospires were 5 x 10(3) and 10(3), respectively. Nonpathogenic leptospires. L. biflexa sv. patoc strain Patoc 1, L. illini strain 3055, Escherichia coli, Bacillus aerogenes capsulatus, and Salmonella anatis, could not be detected by the probes. The study demonstrates that leptospires DNA probe could be produced by labelling the DNA with photobiotin. It has higher sensitivity and specificity and can be used for detection of leptospires in the field and clinic. PMID- 1452140 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992 Jun;23(2):130-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 93084109 AU - Wu Q AU - Xu L AU - Wang X AU - Li S AU - Wang B TI - [Investigation of microbicidal activity of neutrophil defensins against leptospires] LA - Chi MH - Animal MH - *Blood Bactericidal Activity MH - Blood Proteins/*physiology MH - English Abstract MH - Human MH - Leptospira interrogans/*physiology MH - Neutrophils/*immunology MH - Rabbits RN - 0 (defensins) RN - 0 (Blood Proteins) PT - JOURNAL ARTICLE DA - 930107 DP - 1992 Jun IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 126-9 CY - CHINA IP - 2 VI - 23 JC - GEB AA - Author EM - 9303 AB - Defensins play an important role in oxygen-independent microbicidal mechanisms of neutrophils. They are effective against many bacteria, fungi and enveloped viruses. However, the effect of defensins upon leptospires has not been studied. In the present report, human defensins (i.e. HNP, a mixture of HNP1, HNP2 and HNP3 were prepared from human polymorphonuclear neutrophils by chromatography on Sephadex G-100 and then on Biogel P-10. Rabbit defensin NP1 was purified from rabbit peritoneal granulocytes by preparative acid urea polyacrylamide gel electrophoresis. By using the most-probable-number procedure, HNP and NP1 were tested in vitro for the killing of leptospira interrogans serogroup icteroheamorrhagiae serovar lai strain 017. NP1 was highly effective. When leptospires of strain 017 were incubated with 1 microgram/ml of NP1 at 30 degrees C for 4 hours, > 99% of these organisms were killed. HNP was less potent than NP1, and at 50 micrograms/ml, it killed > 90% of leptospires. As is also the case for the killing of bacteria, NP1 was active against leptospires in nutrient- free buffer, whereas HNP required the addition of glucose. The data suggest that defensins could play a major role in the killing of leptospires by neutrophils. PMID- 1452139 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992 Jun;23(2):126-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 93084108 AU - Huang N AU - Dai B TI - [Assay of genomic DNA homology among strains of different virulent leptospira by DNA hybridization] LA - Chi MH - Blotting, Southern MH - DNA, Bacterial/*genetics MH - English Abstract MH - *Genome MH - Leptospira/*genetics MH - Leptospira interrogans/*genetics MH - Nucleic Acid Hybridization MH - *Sequence Homology, Nucleic Acid MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 930107 DP - 1992 Jun IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 122-5 CY - CHINA IP - 2 VI - 23 JC - GEB AA - Author EM - 9303 AB - Nick translation labelling technique was applied to the preparation of two 32P labelled genomic DNA probes from L. interrogans serovar Lai strain 017 and Leptonema illini strain 3055, respectively. Dot-blotting and Southern-blotting with DNA of five strains leptospira from different genus and species were performed. The results showed that certain differences among the L. interrogans, L. biflexa and Leptonema illini could be detected by endonuclease assay. L. interrogans strain 017 with L. biflexa strain Patoc I and Leptonema illini 3055 strain exhibited very little homology. L. interrogans strains 017, 601, and 245 from different serogroup and serovar had a high degree of homology. Leptonema illini strain 3055 showed little homology with L. interrogans and L. biflexa. Therefore DNA hybridization may be used as a tool for the identification and classification of leptospira. PMID- 1452138 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992 Jun;23(2):122-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 93046565 AU - Li Y TI - [Cluster and multiple regression analysis of leptospirosis epidemic factors] LA - Chi MH - Animal MH - Antibodies, Bacterial/blood MH - Cluster Analysis MH - Disease Reservoirs MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Muridae/microbiology MH - Rain MH - Regression Analysis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 921127 DP - 1992 Jun IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 151-3 CY - CHINA IP - 3 VI - 13 JC - CQG AA - Author EM - 9302 AB - Ten-year surveillance of Rice-field-typed leptospirosis was carried out in high-infected foci. Twenty two parameters of epidemic data were divided into 3 categories and cluster-analyzed. 5 typical variables were selected for multiple regression equation. The equation contained four factors, i.e. rodents density, carriage rates of main animal hosts, GMT of population antibody against leptospira and quantity of rainfall in August. The expected morbidity of leptospirosis calculated by the equation were roughly identical to the real morbidity. AD - Sanitary and anti-epidemic Station of Fuling Prefecture, Sichuan Province. PMID- 1423538 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1992 Jun;13(3):151-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 92320680 AU - Feresu SB TI - Isolation of Leptospira interrogans from kidneys of Zimbabwe beef cattle. LA - Eng MH - Abattoirs MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology/*parasitology MH - Female MH - Kidney/*microbiology MH - Leptospira interrogans/classification/*isolation & purification MH - Leptospirosis/epidemiology/parasitology/*veterinary MH - Male MH - Serotyping MH - Support, Non-U.S. Gov't MH - Zimbabwe/epidemiology PT - JOURNAL ARTICLE DA - 920803 DP - 1992 May 16 IS - 0042-4900 TA - Vet Rec PG - 446-8 SB - M CY - ENGLAND IP - 20 VI - 130 JC - XBS AA - Author EM - 9210 AB - Four hundred and eighty bovine kidneys were collected from an abattoir near Harare between December 1987 and November 1988, and leptospires were recovered from 50 (10.4 per cent) of them. The isolates were identified to serogroup level by the microscopic agglutination test; 32 belonged to serogroup Sejroe, seven were Pyogenes, four Hebdomadis, two Tarassovi, and one isolate each belonged to serogroups Australis, Bataviae, Grippotyphosa, Icterohaemorrhagiae and Pomona. AD - Department of Biological Sciences, University of Zimbabwe, Mount Pleasant, Harare. PMID- 1621343 SO - Vet Rec 1992 May 16;130(20):446-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 92328704 AU - Chappel RJ AU - Ellis WA AU - Adler B AU - Amon L AU - Millar BD AU - Zhu SS AU - Prime RW TI - Serological evidence for the presence of Leptospira interrogans serovar bratislava in Australian pigs. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*blood MH - Australia/epidemiology MH - Immunoenzyme Techniques MH - Leptospira interrogans/classification/*immunology MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Swine MH - Swine Diseases/epidemiology/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 920811 DP - 1992 May IS - 0005-0423 TA - Aust Vet J PG - 119-20 SB - M CY - AUSTRALIA IP - 5 VI - 69 JC - 9IE EM - 9210 AD - Department of Agriculture, Victorian Institute of Animal Science, Attwood. PMID- 1627090 SO - Aust Vet J 1992 May;69(5):119-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 92321968 AU - Zieris H TI - [The significance of small mammals in the epizootiology of leptospirosis in livestock] LA - Ger MH - Animal MH - *Animals, Domestic MH - *Disease Vectors MH - English Abstract MH - Leptospirosis/transmission/*veterinary MH - *Microtinae MH - *Muridae PT - JOURNAL ARTICLE DA - 920803 DP - 1992 May 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 155-60 CY - GERMANY IP - 5 VI - 105 JC - 9Q8 AA - Author EM - 9210 AB - 1. Favourite species of rodents in sheds and their surroundings are rats (Rattus norvegicus, R. rattus) and house mouse (Mus musculus). From the epizootiological point of view only R. norvegicus is important as the maintenance host of L. copenhageni. 2. In surrounding of sheds vole (Microtus arvalis) and back-striped field mouse (Apodemus agrarius) are sources of infection for livestock. 3. Transmission of leptospira occurs via infected environment. The tenacity of Leptospira mozdok and L. grippotyphosa under field conditions suffices to maintain the chain of infections. AD - Veterinar- und Lebensmitteluntersuchungsamt Cottbus. PMID- 1622379 TT - Zur Bedeutung von Kleinsaugern in der Epizootiologie der Nutztierleptospirose. EA - A SO - Berl Munch Tierarztl Wochenschr 1992 May 1;105(5):155-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 92320056 AU - Roura Carrasco J AU - Pila Perez R AU - Caveda Estela O AU - Pila Pelaez R TI - [A clinical study of human leptospirosis. Apropos 215 cases] LA - Spa MH - Cuba/epidemiology MH - English Abstract MH - Human MH - Incidence MH - Leptospirosis/complications/diagnosis/*epidemiology MH - Prospective Studies MH - Rural Population/statistics & numerical data MH - Socioeconomic Factors MH - Urban Population/statistics & numerical data MH - Weil's Disease/complications/diagnosis/epidemiology PT - JOURNAL ARTICLE DA - 920806 DP - 1992 May IS - 0014-2565 TA - Rev Clin Esp PG - 389-92 CY - SPAIN IP - 8 VI - 190 JC - RNL AA - Author EM - 9210 AB - 215 cases diagnosed of human leptospirosis in the Camaguey Province, Cuba, are studied, for the period between 1986 and 1990. The clinical and epidemiological features are studied, together with the anatomopathological study of the decreased. The most frequent complications and the treatment employed, including prophylactic measures, are analyzed. It is concluded that the disease is more frequent in young males, from a rural origin and with a farming job. Acute kidney failure was the main complication, and as for the therapeutic approach, penicillin was the antibiotic of election, prophylactic measures are important, specifically vaccination. AD - Hospital Clinico-Quirurgico Docente Manuel Ascunce Domenech, Camaguey, Cuba. PMID- 1620940 TT - Estudio clinico de la leptospirosis humana. A proposito de 215 casos. EA - A SO - Rev Clin Esp 1992 May;190(8):389-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 92286441 AU - Perolat P AU - Poingt JP AU - Vie JC AU - Jouaneau C AU - Baranton G AU - Gysin J TI - Occurrence of severe leptospirosis in a breeding colony of squirrel monkeys. LA - Eng MH - Acute Disease MH - Agglutination Tests MH - Animal MH - Animals, Laboratory MH - Antibodies, Bacterial/biosynthesis MH - Bacterial Vaccines/immunology MH - Disease Outbreaks/*veterinary MH - Doxycycline/therapeutic use MH - IgG/biosynthesis MH - Leptospira interrogans/*classification/immunology/isolation & purification MH - Leptospirosis/epidemiology/pathology/prevention & control/*veterinary MH - Monkey Diseases/*epidemiology/pathology/prevention & control MH - Radioimmunoassay MH - *Saimiri MH - Vaccines, Inactivated/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (IgG) RN - 0 (Vaccines, Inactivated) RN - 564-25-0 (Doxycycline) PT - JOURNAL ARTICLE DA - 920706 DP - 1992 May IS - 0002-9637 TA - Am J Trop Med Hyg PG - 538-45 SB - A SB - M CY - UNITED STATES IP - 5 VI - 46 JC - 3ZQ AA - Author EM - 9209 AB - Although experimental leptospirosis has been studied in various species of monkeys, the occurrence of acute leptospirosis in a population of nonhuman primates is uncommon. We report on a number of severe cases of icterohemorrhagic leptospirosis that appeared in the squirrel monkey (Saimiri sciureus) colony of 109 animals at the Institute Pasteur in French Guiana. Initially, 11 animals had acute illness, with jaundice and a hemorrhagic syndrome, leading to 10 deaths. Two Leptospira interrogans strains were isolated from blood cultures of sick monkeys, and one was isolated from the urine of a rat trapped in the breeding park. All three belonged to serovar copenhageni, and tests using monoclonal antibodies showed that these three strains were extremely similar. In the following weeks, five pregnant female monkeys had miscarriages; two of them had antibodies against the Icterohaemorrhagiae serogroup. An epidemiologic study conducted on the 93 remaining animals demonstrated a seropositivity rate of 26% (microagglutination test [MAT] titer greater than or equal to 100) primarily for the Icterohaemorrhagiae serogroup, but also for the Ballum, Grippotyphosa, Sejroe, and Panama serogroups. In addition, 12% showed lower MAT titers (50) for the same serogroups. Lastly, recently trapped feral squirrel monkeys were shown to have agglutinins against the Grippotyphosa and Sejroe serogroups. A vaccine, which was prepared from one of the strains isolated, was used in addition to antibiotic prophylaxis to control the enzootic disease. This confirms that the squirrel monkey is highly susceptible to icterohemorrhagic leptospirosis and is probably receptive to other serogroups, and that this animal may be useful in studying experimental leptospirosis and for testing new human vaccines. AD - Unite des Leptospires, Institut Pasteur, Paris, France. PMID- 1599047 CU - 92 SO - Am J Trop Med Hyg 1992 May;46(5):538-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 92259616 AU - Pacciarini ML AU - Savio ML AU - Tagliabue S AU - Rossi C TI - Repetitive sequences cloned from Leptospira interrogans serovar hardjo genotype hardjoprajitno and their application to serovar identification. LA - Eng MH - Blotting, Southern MH - Cloning, Molecular MH - DNA, Bacterial/*analysis MH - Genotype MH - Leptospira interrogans/*genetics MH - *Repetitive Sequences, Nucleic Acid MH - Restriction Mapping MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 920617 DP - 1992 May IS - 0095-1137 TA - J Clin Microbiol PG - 1243-9 SB - M CY - UNITED STATES IP - 5 VI - 30 JC - HSH AA - Author EM - 9208 AB - We selected, from a genomic library of Leptospira interrogans serovar hardjo genotype hardjoprajitno, two probes containing repetitive sequences (pL1 and pL590). The hybridization patterns of these probes to DNA isolated from a variety of Leptospira serovars were examined and their ability to detect subtle differences at the genomic organization level was established. We identified the DNA fragments within pL1 and pL590 which are sufficient to yield polymorphic hybridization patterns; these results define the upper size limit of two novel repetitive elements in the Leptospira genome. The pattern and degree of hybridization observed for the serovars tested in this work were used to divide Leptospira spp. into groups which share genetic relatedness; our conclusions are consistent with previous classifications by other authors. AD - Istituto Zooprofilattico della Lombardia e dell' Emilia, Brescia, Italy. PMID- 1583126 SO - J Clin Microbiol 1992 May;30(5):1243-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 94098137 AU - da Silva MV AU - Camargo ED TI - [An immunoenzyme test (ELISA) for the detection of circulating class- IgA antibodies in human leptospirosis] LA - Por MH - Adolescence MH - Adult MH - Antibodies, Bacterial/*blood MH - Biological Markers/blood MH - Chi-Square Distribution MH - Comparative Study MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay/methods/statistics & numerical data MH - Female MH - Human MH - IgA/*blood MH - IgM/blood MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/*immunology MH - Male MH - Middle Age MH - Weil's Disease/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Biological Markers) RN - 0 (IgA) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 940202 DP - 1992 May-Jun IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 239-42 CY - BRAZIL IP - 3 VI - 34 JC - S9D AA - Author EM - 9404 AB - An enzyme-linked immunosorbent assay ELISA was evaluated for the detection of IgA antibodies in the human leptospirosis. The assay proved to be sensitive and specific when compared with the ELISA-IgM, in the examined serum samples. The results found suggest that IgA antibodies became positive later in leptospirosis, and will can be an evolutive indicator in the development of the disease. AD - Secao de Sorologia, Instituto Adolfo Lutz, Secretaria de Saude do Estado de Sao Paulo, Brasil. PMID- 1342077 TT - Teste imunoenzimatico (ELISA) para deteccao de anticorpos circulantes da classe IgA na leptospirose humana. EA - A SO - Rev Inst Med Trop Sao Paulo 1992 May-Jun;34(3):239-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 94098133 AU - Sakata EE AU - Yasuda PH AU - Romero EC AU - Silva MV AU - Lomar AV TI - [The serovars of Leptospira interrogans isolated from cases of human leptospirosis in Sao Paulo, Brazil] LA - Por MH - Agglutination Tests MH - Brazil/epidemiology MH - English Abstract MH - Human MH - Leptospira interrogans/*classification/isolation & purification MH - Prevalence MH - Seroepidemiologic Methods MH - Serotyping MH - Weil's Disease/epidemiology/*microbiology PT - JOURNAL ARTICLE DA - 940202 DP - 1992 May-Jun IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 217-21 CY - BRAZIL IP - 3 VI - 34 JC - S9D AA - Author EM - 9404 AB - Eighteen strains of L. interrogans isolated from human cases were serotyped by the agglutinin-absorption test at Instituto Adolfo Lutz in Sao Paulo, Brazil. Fourteen were identified as serovar copenhageni (icterohaemorrhagiae serogroup), 2 as canicola (canicola serogroup), 1 as castellonis (Ballum serogroup) and 1 as pomona serogroup (serovar not yet defined). The frequency of serovar copenhageni in 100% of the isolates in icterohaemorrhagiae serogroup is emphasized and more studies to verify the real serovars prevalence as subsidy to the epidemiology of this infection are suggested by the authors. AD - Secao de Bacteriologia, Setor de Leptospirose, Instituto Adolfo Lutz, Sao Paulo, Brasil. PMID- 1342073 TT - Sorovares de Leptospira interrogans isolados de casos de leptospirose humana em Sao Paulo, Brasil. EA - A SO - Rev Inst Med Trop Sao Paulo 1992 May-Jun;34(3):217-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 93289629 AU - el-Sukhon SN AU - Abo-Shehada MN AU - Abuharfiel N AU - Atmeh RF TI - Prevalence of leptospiral antibodies in cattle in northern Jordan. LA - Eng MH - Animal MH - Antibodies, Bacterial/*isolation & purification MH - Cattle MH - Cattle Diseases/*immunology MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Jordan MH - Leptospira/*immunology MH - Leptospirosis/blood/immunology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930709 DP - 1992 May IS - 0049-4747 TA - Trop Anim Health Prod PG - 127-8 SB - M CY - SCOTLAND IP - 2 VI - 24 JC - WG2 EM - 9309 AD - Department of Veterinary Medicine and Animal Science, Jordan University of Science and Technology, Irbid. PMID- 1305336 SO - Trop Anim Health Prod 1992 May;24(2):127-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 92312102 AU - Mendoza L AU - Prescott JF TI - Serodiagnosis of leptospirosis in pigs using an axial filament enzyme- linked immunosorbent assay. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*blood MH - Antigens, Bacterial/diagnostic use/*immunology/isolation & purification MH - Centrifugation, Density Gradient MH - Comparative Study MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Immunoblotting MH - Leptospira interrogans/*immunology/ultrastructure MH - Leptospirosis/diagnosis/*veterinary MH - Microscopy, Electron MH - Sensitivity and Specificity MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 920727 DP - 1992 Apr IS - 0378-1135 TA - Vet Microbiol PG - 55-70 SB - M CY - NETHERLANDS IP - 1 VI - 31 JC - XBW AA - Author EM - 9210 AB - The axial filament (AF) from Leptospira interrogans serovar canicola was isolated by cesium chloride density gradient centrifugation of 2% sarcosyl treated whole cells. Isolation of AF was confirmed by electron microscopic examination, by protein-A immunogold labelling, sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE), and immunoblotting. Analysis by SDS-PAGE of the purified preparation showed relatively weak bands of molecular size 41 kDa and 21 kDa, and strong bands of 35 kDa and 34.5 kDa. Immunoblot analysis using antiserum to the AF against sonicated leptospires of a variety of serovars showed prominent reaction against the 41, 35, and 34.5 kDa protein bands, as well as against minor bands of molecular weight 43, 39, and 37 kDa. Antisera prepared against leptospiral serovars also identified minor bands at 33 and 32 kDa. Immunoblots with antiserum to whole cells of serovar bratislava detected the 35 and 34.5 kDa AF bands of Borrelia burgdorferi moderately and of Treponema hyodysenteriae only slightly in comparison to leptospiral AF. Antibody to B. burgdorferi did not detect the leptospiral AF antigen. Immunoblots with antiserum to T. hyodysenteriae showed a marked reaction with a 41 kDa band of B. burgdorferi but only a very minor reaction with leptospiral AF. The AF was tested in an AF-ELISA against sera from 260 pigs, many of which reacted in the microscopic agglutination test (MAT) against one or more leptospiral serovars. A sensitivity of 97.1% and a specificity of 93.1% was determined in comparison to the MAT. Only moderate correlation was observed between titres detected in the AF-ELISA and the MAT (r = 0.4). When sonicated whole cells (WC) of serovar canicola were used in an ELISA (WC-ELISA), high correlation was observed between AF-ELISA and WC- ELISA (r = 0.97). These findings show that the AF-ELISA can be used effectively as a species-specific antigen for the serological diagnosis of leptospirosis in swine and that sonicated whole cells can substitute excellently for purified AF as the antigen source. These findings may be extrapolated to the use of AF in immunodiagnosis of leptospirosis in other species. AD - Department of Veterinary Microbiology and Immunology, University of Guelph, Ontario, Canada. PMID- 1615635 SO - Vet Microbiol 1992 Apr;31(1):55-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 92306011 AU - de Souza L AU - Koury MC TI - Isolation and biological activities of endotoxin from Leptospira interrogans. LA - Eng MH - Animal MH - Cell Death/drug effects MH - Cells, Cultured MH - Chick Embryo MH - Edetic Acid MH - Endotoxins/immunology/*isolation & purification/toxicity MH - Hemolysis/drug effects MH - Leptospira interrogans/*chemistry MH - Lethal Dose 50 MH - Limulus Test MH - Pyrogens/toxicity MH - Rabbits RN - 0 (Endotoxins) RN - 0 (Pyrogens) RN - 60-00-4 (Edetic Acid) PT - JOURNAL ARTICLE DA - 920729 DP - 1992 Apr IS - 0008-4166 TA - Can J Microbiol PG - 284-9 SB - M CY - CANADA IP - 4 VI - 38 JC - CJ3 AA - Author EM - 9210 AB - Endotoxins extracted with ethylenediaminetetraacetate (EDTA) from Leptospira interrogans serovars icterohaemorrhagiae and canicola and Leptospira biflexa serovar patoc were tested for various biological activities characteristic of endotoxins. The presence of lipopolysaccharide biological activity was demonstrated by the Limulus amoebocyte lysate test, pyrogenicity in rabbits, complement interaction inhibiting the erythrocyte lysis, and chicken-embryo lethality. The lipopolysaccharides did not induce the local Shwartzman reaction. The lipopolysaccharides of serovars icterohaemorrhagiae and canicola were immunogenic in rabbits and were cytotoxic to chicken-embryo fibroblasts. AD - Departamento de Microbiologia, Instituto de Ciencias Biologicas da Universidade Federal de Minas Gerais, Brasil. PMID- 1611553 SO - Can J Microbiol 1992 Apr;38(4):284-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 92256164 AU - Ramadass P AU - Jarvis BD AU - Corner RJ AU - Penny D AU - Marshall RB TI - Genetic characterization of pathogenic Leptospira species by DNA hybridization. LA - Eng MH - DNA, Bacterial MH - Leptospira/classification/*genetics/pathogenicity MH - Nucleic Acid Hybridization MH - Phenotype MH - Phylogeny MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 920612 DP - 1992 Apr IS - 0020-7713 TA - Int J Syst Bacteriol PG - 215-9 SB - M CY - UNITED STATES IP - 2 VI - 42 JC - AWO AA - Author EM - 9208 AB - A total of 66 serovars of potentially pathogenic Leptospira species were examined by slot blot hybridization, and 57 of these serovars were classified in six DNA homology groups. In cases in which common serovars were studied, the results were in general agreement with the results of previous workers, who used different DNA homology methods. However, we propose a new species, Leptospira kirschneri, comprising the following serovars: bulgarica, butembo, cynopteri, dania, grippotyphosa, kabura, kambale, ramisi, and tsaratsovo. Seven of these serovars have not had their DNAs studied by other workers. AD - Department of Veterinary Pathology and Public Health, Faculty of Veterinary Science, Massey University, Palmerston North, New Zealand. PMID- 1581182 SO - Int J Syst Bacteriol 1992 Apr;42(2):215-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 92242456 AU - Schwan TG AU - Gage KL AU - Karstens RH AU - Schrumpf ME AU - Hayes SF AU - Barbour AG TI - Identification of the tick-borne relapsing fever spirochete Borrelia hermsii by using a species-specific monoclonal antibody. LA - Eng MH - Antibodies, Bacterial MH - *Antibodies, Monoclonal MH - Borrelia/*immunology/isolation & purification/ultrastructure MH - Fluorescent Antibody Technique MH - Human MH - Microscopy, Immunoelectron MH - Relapsing Fever/diagnosis/*microbiology MH - Species Specificity RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 920529 DP - 1992 Apr IS - 0095-1137 TA - J Clin Microbiol PG - 790-5 SB - M CY - UNITED STATES IP - 4 VI - 30 JC - HSH AA - Author EM - 9208 AB - Borrelia hermsii causes a relapsing fever in humans and is one of several species of tick-borne spirochetes known to occur in the western United States. Spirochetes observed in the peripheral blood of patients acutely ill have been presumptively identified in the past by the geographic location of exposure and the probable species of tick vector. We describe a monoclonal antibody (H9826) that bound to the flagellar protein of B. hermsii but not to those of any of the other species tested, which included B. parkeri, B. turicatae, B. coriaceae, B. anserina, B. burgdorferi, and Leptospira interrogans serovar ballum. This antibody bound efficiently to B. hermsii in an indirect immunofluorescence assay and was used to rapidly detect and identify this spirochete in the peripheral blood of experimentally infected mice and in the central ganglia of Ornithodoros hermsi ticks. H9826 can rapidly confirm the identification of B. hermsii to increase our understanding concerning the geographic distribution, vector specificity, and epidemiological significance of this zoonotic human pathogen. AD - Arthropod-Borne Diseases Section, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840. PMID- 1572965 SO - J Clin Microbiol 1992 Apr;30(4):790-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [81 medline neighbors] UI - 92192853 AU - Segers RP AU - van Gestel JA AU - van Eys GJ AU - van der Zeijst BA AU - Gaastra W TI - Presence of putative sphingomyelinase genes among members of the family Leptospiraceae. LA - Eng MH - Blotting, Southern MH - Comparative Study MH - Genes, Bacterial MH - Leptospiraceae/*enzymology MH - Nucleic Acid Hybridization MH - Sphingomyelin Phosphodiesterase/*genetics MH - Support, Non-U.S. Gov't RN - EC 3.1.4.12 (Sphingomyelin Phosphodiesterase) PT - JOURNAL ARTICLE DA - 920423 DP - 1992 Apr IS - 0019-9567 TA - Infect Immun PG - 1707-10 SB - M SB - X CY - UNITED STATES IP - 4 VI - 60 JC - GO7 AA - Author EM - 9206 AB - The presence of multiple DNA elements in pathogenic members of the family Leptospiraceae, similar to the sphA sphingomyelinase gene from Leptospira borgpetersenii, was demonstrated by low-stringency hybridization experiments. These DNA elements were designated putative sphingomyelinase genes. Grouping of strains by similarity of hybridization patterns corresponds to the species subdivision of the family Leptospiraceae on the basis of genetic characteristics. Therefore, hybridization with the sphA gene can be used as a taxonomic tool. These hybridization experiments indicate the presence of two groups of genetically related pathogenic Leptospira species. AD - Department of Bacteriology, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands. PMID- 1548095 GS - sphA SO - Infect Immun 1992 Apr;60(4):1707-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 92242463 AU - Ito F AU - Hunter EF AU - George RW AU - Pope V AU - Larsen SA TI - Specific immunofluorescent staining of pathogenic treponemes with a monoclonal antibody. LA - Eng MH - Animal MH - Antibodies, Bacterial MH - *Antibodies, Monoclonal MH - Antibody Specificity MH - Cross Reactions MH - Evaluation Studies MH - Fluorescein-5-isothiocyanate MH - Fluorescent Antibody Technique MH - Species Specificity MH - Staining MH - Syphilis/diagnosis MH - Treponema pallidum/*immunology/pathogenicity RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 3326-32-7 (Fluorescein-5-isothiocyanate) PT - JOURNAL ARTICLE DA - 920529 DP - 1992 Apr IS - 0095-1137 TA - J Clin Microbiol PG - 831-8 SB - M CY - UNITED STATES IP - 4 VI - 30 JC - HSH AA - Author EM - 9208 AB - Two hybrid cell lines which produced mouse monoclonal antibody to the DAL-1 street strain of Treponema pallidum subsp. pallidum were established. These monoclonal antibodies strongly reacted with T. pallidum subsp. pallidum (Nichols strain, DAL-1, and two other street strains, strains MN-1 and MN-3) and T. pallidum subsp. pertenue by indirect microimmunofluorescent antibody and enzyme-linked immunosorbent assay techniques, but they did not react with normal rabbit testicular tissue. These monoclonal antibodies did not react with nonpathogenic treponemes, such as T. phagedenis Reiter, T. denticola MRB, T. refringens Noguchi, or other spirochetes, such as Borrelia burgdorferi and Leptospira interrogans serovar pomona in microimmunofluorescent antibody smear slides or in Western blots (immunoblots). While unlabeled antibodies are useful for investigating the antigenic structures of T. pallidum, we labeled these monoclonal antibodies with fluorescein isothiocyanate and used them for diagnosing syphilis by direct staining of lesion exudate or T. pallidum subsp. pallidum in formalin-fixed tissues from patients suspected of having syphilis. Both monoclonal antibodies were directed against antigens of T. pallidum subsp. pallidum with a molecular weight of 37,000 as determined by the Western blotting technique. AD - Department of Dermatology, Second Hospital of Nippon Medical School, Kanagawa, Japan. PMID- 1374079 CU - 95 SO - J Clin Microbiol 1992 Apr;30(4):831-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 92202726 AU - Coleman JL AU - Benach JL TI - Characterization of antigenic determinants of Borrelia burgdorferi shared by other bacteria. LA - Eng MH - Amino Acid Sequence MH - Animal MH - Antibodies, Monoclonal/immunology MH - Antibody Specificity MH - Antigens, Bacterial/*analysis/chemistry/immunology MH - Bacteroides fragilis/immunology MH - Blotting, Western MH - Borrelia burgdorferi/*immunology MH - Cross Reactions MH - Enterobacteriaceae/immunology MH - Enzyme-Linked Immunosorbent Assay MH - Epitopes/analysis/chemistry/immunology MH - Heat-Shock Proteins/chemistry/immunology MH - Immune Sera/immunology MH - Leptospira interrogans/immunology MH - Molecular Sequence Data MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Ticks/*microbiology MH - Treponema/immunology RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) RN - 0 (Heat-Shock Proteins) RN - 0 (Immune Sera) PT - JOURNAL ARTICLE ID - AI-27044/AI/NIAID DA - 920424 DP - 1992 Apr IS - 0022-1899 TA - J Infect Dis PG - 658-66 SB - A SB - M CY - UNITED STATES IP - 4 VI - 165 JC - IH3 AA - Author EM - 9207 AB - Three antigenic determinants of Borrelia burgdorferi that were shared with other spirochetes and gram-negative bacterial species, as measured by Western blot, ELISA, or both, were identified and characterized using monoclonal antibodies (MAbs). Two were associated with immunogenic integral membrane lipoproteins of 19- and 22-kDa, respectively, by [3H]palmitate incorporation and Triton X-114 phase partitioning. A third antigenic determinant was shown to be associated with a 72-kDa heat shock protein that was also immunogenic in human patients. MAb agglutination assays with B. burgdorferi and treatment of the spirochete with proteases indicated that none of the antigenic determinants were surface exposed. NH2-terminal sequence analysis revealed the 72-kDa protein to have 100% identity with the first 13 amino acid residues of the Escherichia coli dnaK heat shock protein. The presence of these and other shared antigenic determinants in ELISA antigen preparations could explain the high degree of serologic cross- reactivity in current diagnostic procedures. AD - State of New York Department of Health, State University of New York, Stony Brook 11794. PMID- 1372635 CU - 95 SO - J Infect Dis 1992 Apr;165(4):658-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 92292315 AU - Garcelon DK AU - Wayne RK AU - Gonzales BJ TI - A serologic survey of the island fox (Urocyon littoralis) on the Channel Islands, California. LA - Eng MH - Adenoviridae/immunology MH - Adenoviridae Infections/epidemiology/veterinary MH - Animal MH - Antibodies, Bacterial/blood MH - Antibodies, Protozoan/blood MH - Antibodies, Viral/blood MH - California/epidemiology MH - Coronaviridae/immunology MH - Coronaviridae Infections/epidemiology/veterinary MH - Distemper/epidemiology MH - Distemper Virus, Canine/immunology MH - *Foxes MH - Herpesviridae/immunology MH - Herpesviridae Infections/epidemiology/veterinary MH - Leptospira/immunology MH - Leptospirosis/epidemiology/*veterinary MH - Parvoviridae/immunology MH - Parvoviridae Infections/epidemiology/veterinary MH - Prevalence MH - Support, Non-U.S. Gov't MH - Toxoplasma/immunology MH - Toxoplasmosis, Animal/*epidemiology MH - Virus Diseases/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Protozoan) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 920714 DP - 1992 Apr IS - 0090-3558 TA - J Wildl Dis PG - 223-9 SB - M CY - UNITED STATES IP - 2 VI - 28 JC - KEM AA - Author EM - 9209 AB - The island fox is listed as a threatened species in California. A serologic survey of 194 island foxes (Urocyon littoralis) was conducted over the entire range of the species on the Channel Islands (California, USA). Antibody prevalence against canine adenovirus and canine parvovirus reached 97% and 59%, respectively, in some populations sampled. Antibody prevalence of canine herpesvirus, canine coronavirus, leptospirosis and toxoplasmosis were low. Antibodies against canine distemper virus were not detected. AD - Institute for Wildlife Studies, Arcata, California 95521. PMID- 1318424 CU - 93 SO - J Wildl Dis 1992 Apr;28(2):223-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 92244882 AU - Tourbah A AU - Fontaine B AU - Veil N AU - Mazetti P AU - Lyon-Caen O TI - [Lymphocytic meningitis caused by Leptospira panama (letter)] LA - Fre MH - Aged MH - Case Report MH - Female MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/cerebrospinal fluid/*microbiology MH - *Lymphocytes MH - Meningitis, Bacterial/cerebrospinal fluid/*microbiology PT - LETTER DA - 920601 DP - 1992 Mar 21 IS - 0755-4982 TA - Presse Med PG - 536 SB - M SB - X CY - FRANCE IP - 11 VI - 21 JC - PMT EM - 9208 PMID- 1533461 TT - Meningite lymphocytaire a Leptospira panama. SO - Presse Med 1992 Mar 21;21(11):536 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 92354663 AU - Andre-Fontaine G AU - Peslerbe X AU - Ganiere JP TI - Occupational hazard of unnoticed leptospirosis in water ways maintenance staff. LA - Eng MH - Adult MH - Animal MH - Comparative Study MH - Disease Reservoirs MH - France/epidemiology MH - Human MH - Leptospirosis/epidemiology/*microbiology MH - Occupational Diseases/epidemiology/*microbiology MH - Questionnaires MH - Recreation MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 920908 DP - 1992 Mar IS - 0392-2990 TA - Eur J Epidemiol PG - 228-32 SB - M CY - ITALY IP - 2 VI - 8 JC - ERE AA - Author EM - 9211 AB - A serological survey was performed with M.A.T. on the maintenance staff of water ways and public works and lock keepers to study the occupational hazards of leptospirosis. The target population was 58 professional people, 40 working on French rivers and 18 on a channel in the same western area of France. When we compared serological tests between these two groups, no significant difference appeared. But when we linked fish handling to close contact with water, we found a higher number of positive tests in the channel group than in the rivers group (P less than 0.01). We conclude that people working on the channel were susceptible to unnoticed Leptospira infection. AD - Ecole Nationale Veterinaire de Nantes, Service de Maladies Contagieuses, France. PMID- 1644140 SO - Eur J Epidemiol 1992 Mar;8(2):228-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 92351508 AU - Bakoss P AU - Jarekova J AU - Kmety E AU - Kopcok M TI - [Leptospirosis in dogs in Slovakia] LA - Slo MH - Animal MH - Czechoslovakia/epidemiology MH - Dog Diseases/*epidemiology MH - Dogs MH - English Abstract MH - Leptospirosis/epidemiology/*veterinary MH - Seroepidemiologic Methods PT - JOURNAL ARTICLE DA - 920828 DP - 1992 Mar IS - 0375-8427 TA - Vet Med (Praha) PG - 185-92 CY - CZECHOSLOVAKIA IP - 3 VI - 37 JC - XBP AA - Author EM - 9211 AB - Out of 571 serologically investigated dogs from Bratislava and all regions of Slovakia and Moravia, 26.1% presented antibodies reacting with leptospiral antigens. The lowing seropositivity in dogs from Bratislava was found in lap dogs--11.1%, the highest one in farm dogs-- 35.3% (Tab. I). The seropositivity of police dogs from different regions of Slovakia and Moravia varied from 24.0% to 47.6% (Tab. II). The age of dogs progressing, their seropositivity rose from 3.1% in animals younger than one year to 33.3% in those aged seven years and in older ones (Tab. III). The predominant serovars causing infections of dogs were L. grippotyphosa (58.9% of infections) and serovars of both Sejroe (21.0%) and Icterohaemorrhagiae groups (15.3%). The serovars bratislava/jalna, pomond/mozdok and tarassovi were only rarely involved in these infections, canicola and arborea only exceptionally (Tab. IV). At present, in the Czechoslovak conditions the dogs do not play a significant role as reservoirs of human leptospirosis, and the predominant serovars may only cause irregular and short-time lasting leptospiruria. This is why the reasonableness of actual vaccination of dogs, possibly with the exception of the vaccination against Weil's disease, is doubtful. Dog is a good indicator of the distribution of different leptospiral serovars in its environment. It seems reasonable to practice occasionally serological investigations of these animals in order to detect possible changes in infecting leptospiral serovars. Consequently, adequate epizootological measures could be taken (e. g. modification of the composition of a leptospiral vaccine for dogs). AD - Ustav epidemiologie Lekarskej fakulty UK, Bratislava. PMID- 1641948 TT - Premorenie psov na Slovensku leptospirami. EA - A SO - Vet Med (Praha) 1992 Mar;37(3):185-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 92283290 AU - Bruckbauer HR AU - Preac-Mursic V AU - Fuchs R AU - Wilske B TI - Cross-reactive proteins of Borrelia burgdorferi. LA - Eng MH - Antigens, Bacterial/blood/*immunology MH - Bacteria/immunology MH - Bacterial Proteins/*immunology MH - Blotting, Western MH - Borrelia burgdorferi/*immunology MH - Comparative Study MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique MH - Lyme Disease/*diagnosis/immunology MH - Sensitivity and Specificity RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE DA - 920708 DP - 1992 Mar IS - 0934-9723 TA - Eur J Clin Microbiol Infect Dis PG - 224-32 SB - M CY - GERMANY IP - 3 VI - 11 JC - EM5 AA - Author EM - 9209 AB - The specificity of serological tests for Lyme borreliosis is impaired by cross-reacting antibodies. In order to select antigens for more specific tests, specific and cross-reactive proteins of Borrelia burgdorferi must be identified. Therefore, to analyze cross reactions of Borrelia burgdorferi with other bacteria, rabbit immune sera against heterologous bacteria (Borrelia hermsii, Treponema pallidum, Treponema phagedenis, Leptospira interrogans (serogroup grippotyphosa), Neisseria meningitidis, Haemophilus influenzae, Yersinia enterocolitica (serotypes O3 and O9), Campylobacter jejuni, Listeria monocytogenes O1, Pseudomonas aeruginosa, Escherichia coli, Salmonella typhimurium, Shigella flexneri and Legionella micdadei) were examined by Western blot using Borrelia burgdorferi as antigen. Broad cross reactivity was shown for Borrelia proteins of the 60-75 kDa range. Other broadly cross- reacting proteins were at the level of p40, p33 and two proteins in the range of 20 kDa. Some of the cross reactions were eliminated by absorption of the sera with Treponema phagedenis. The absorbed antibodies were directed mainly against bands at the level of p33 and bands of the 60 to 75 kDa range. Showing the lowest potential for cross reactivity, p100, p41, OspA and pC seem to be the most suitable antigens for serodiagnosis. In contrast to p100 and OspA, however, p41 and pC showed cross reactivity with immune sera against bacteria not belonging to the genus Borrelia. AD - Max von Pettenkofer Institute, University of Munich, Germany. PMID- 1597198 SO - Eur J Clin Microbiol Infect Dis 1992 Mar;11(3):224-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 92214744 AU - Shinozaki F AU - Sada E AU - Tamai T AU - Kobayashi Y TI - Characterization of Leptospira strains HY-1, HY-2, and HY-10 isolated in Korea by means of monoclonal antibodies and restriction endonuclease DNA analysis. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Monoclonal/biosynthesis/*immunology MH - DNA, Bacterial/*analysis MH - Female MH - Human MH - Hybridomas MH - Immunodiffusion MH - Korea MH - Leptospira interrogans/*classification/genetics/immunology MH - Mice MH - Mice, Inbred BALB C MH - Restriction Mapping RN - 0 (Antibodies, Monoclonal) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 920504 DP - 1992 Mar IS - 0002-9637 TA - Am J Trop Med Hyg PG - 342-9 SB - A SB - M CY - UNITED STATES IP - 3 VI - 46 JC - 3ZQ AA - Author EM - 9207 AB - To analyze the characteristics of Leptospira strains HY-1, HY-2, and HY- 10, which were isolated from patients with leptospirosis in Korea in 1985, 12 monoclonal antibodies (MAbs) against strain HY-1 and six MAbs against serovar lai strain 017 were produced, and their properties were determined by the microscopic agglutination test. Genetic relationships among the leptospires were determined by restriction endonuclease DNA analysis. Three MAbs reacted with all strains of serogroup Icterohaemorrhagiae, but did not react with any strains of the other 10 serogroups. All MAbs reacted with strains 017, HY-1, HY-2, and HY-10 at nearly identical titers. Two MAbs reacted only with these four strains. These four strains also had the same restriction endonuclease cleavage patterns. Based on these results, strains HY-1, HY-2, and HY-10 were identified as serovar lai, which is one of the common serovars in China. It is suggested that serovar lai is one of the prevalent serovars in Korea, and that the Mabs produced in this study are useful for the accurate and rapid identification of this serovar. AD - First Department of Internal Medicine, School of Medicine, Ehime University, Japan. PMID- 1558273 SO - Am J Trop Med Hyg 1992 Mar;46(3):342-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 92202397 AU - Schwan TG AU - Schrumpf ME AU - Gage KL AU - Gilmore RD Jr TI - Analysis of Leptospira spp., Leptonema illini, and Rickettsia rickettsii for the 39-kilodalton antigen (P39) of Borrelia burgdorferi. LA - Eng MH - Antibodies, Bacterial/blood MH - Antigens, Bacterial/*analysis/chemistry MH - Borrelia burgdorferi/*immunology MH - Comparative Study MH - Cross Reactions MH - False Positive Reactions MH - Human MH - Leptospira/immunology MH - Lyme Disease/diagnosis/immunology MH - Molecular Weight MH - Rickettsia rickettsii/immunology MH - Serodiagnosis MH - Species Specificity RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 920429 DP - 1992 Mar IS - 0095-1137 TA - J Clin Microbiol PG - 735-8 SB - M CY - UNITED STATES IP - 3 VI - 30 JC - HSH AA - Author EM - 9207 AB - Five serovars of Leptospira interrogans, Leptospira biflexa, Leptonema illini, and Rickettsia rickettsii were examined and found not to contain the 39-kDa antigen (P39) of Borrelia burgdorferi, the Lyme disease spirochete. The specificity of this antigen and its reactivity with human Lyme disease sera should exclude the possibility of false- positive serum samples from patients having had either leptospirosis or Rocky Mountain spotted fever, as well as tick-borne relapsing fever and syphilis, as reported previously (W.J. Simpson, M. E. Schrumpf, and T. G. Schwan, J. Clin. Microbiol. 28:1329-1337, 1990). AD - Arthropod-Borne Diseases Section, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840. PMID- 1551994 SO - J Clin Microbiol 1992 Mar;30(3):735-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 92399845 AU - Cifuentes EE TI - [Protection of the environment and veterinary public health activities] LA - Spa MH - Animal MH - *Developing Countries MH - Education, Veterinary MH - English Abstract MH - *Environmental Health MH - Human MH - Hygiene MH - Poverty MH - *Public Health MH - Sanitation MH - *Veterinary Medicine MH - Zoonoses PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 921020 DP - 1992 Mar IS - 0253-1933 TA - Rev Sci Tech PG - 191-203 SB - M CY - FRANCE IP - 1 VI - 11 JC - A9R AA - Author EM - 9212 AB - The author discusses the health status of 800 million persons who live in developing countries under conditions of absolute misery, and the 450 million on the brink of starvation, taking into account environmental factors which directly affect this situation of shortages, illness and death. Data are presented on diseases directly related to environmental conditions: 200 million people infested with schistosomes and 500 million at risk of infestation. In the case of Chagas' disease, 16 to 18 million are infected and 90 million at risk. The epidemiological situation regarding plague, the epidemiological risks of leptospirosis, the taeniasis-cysticercosis complex and other infectious and parasitic diseases are discussed. A description is given of the organisation and function of veterinary public health services, with comments on, and justification of the various activities which can be undertaken to prevent, reduce and even eradicate various diseases associated with poor hygienic conditions in the environment. Finally, proposals are made to revise the academic instruction of veterinarians. There is an urgent need to promote collaboration between institutes and between disciplines if the environment is to be protected and lives saved. AD - Organizacion Panamericana de la Salud, Oficina Regional de la Organizacion Mundial de la Salud, Mexico, D.F. RF - 5 PMID- 1525417 TT - Proteccion del medio ambiente y actividades de salud publica veterinaria. EA - A SO - Rev Sci Tech 1992 Mar;11(1):191-203 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 92367340 AU - Cho SN AU - Uhm JR AU - Kim JD TI - Comparative analysis of lipopolysaccharide and lipid antigens of Leptospira interrogans serovars. LA - Eng MH - Antigens, Bacterial/*analysis MH - Chromatography, Thin Layer MH - Comparative Study MH - Electrophoresis, Polyacrylamide Gel MH - Leptospira interrogans/*chemistry/immunology MH - Lipids/*analysis/immunology MH - Lipopolysaccharides/*analysis/immunology MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (Lipids) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 920914 DP - 1992 Mar IS - 0513-5796 TA - Yonsei Med J PG - 24-31 CY - KOREA IP - 1 VI - 33 JC - XRR AA - Author EM - 9211 AB - Lipopolysaccharide (LPS) or glycolipid antigens of Leptospira interrogans have been candidates as serogroup or serotype specific antigen. In this study, therefore, we prepared the LPS and lipid antigens from L. interrogans serovars lai, icterohaemorrhagiae, copenhageni, canicola, pomona, grippotyphosa, and a Korean isolate 30R. The LPS antigens were analyzed by a polyacrylamide gel electrophoresis and lipid antigens by thin-layer chromatography, respectively. The seroreactivity of the antigens were also examined with homologous or heterologous antisera using an enzyme-linked immunosorbent assay. The LPS antigens from serovar lai and the strain 30R were closely related but different from serovar icterohaemorrhagiae. Particularly, the LPS antigens from serovars icterohaemorrhagiae and grippotyphosa were reactive only with the homologous antisera, thus indicating serovar specificity. However, the LPS antigens of the other serovars were reactive to the heterologous antisera. The lipid antigen of serovar icterohaemorrhagiae reacted only with the homologous antisera. In contrast, lipids of other serovars reacted broadly with heterologous antisera, particularly among serovars lai, copenhageni, canicola, pomona, and the strain 30R. The results thus indicated that the LPS and lipid antigens of L. interrogans may contain serovar-specific as well as cross-reactive epitopes. AD - Department of Microbiology, Yonsei University College of Medicine, Seoul, Korea. PMID- 1502827 SO - Yonsei Med J 1992 Mar;33(1):24-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 93013738 AU - Zhao H AU - Li S AU - Dai B AU - Gan D AU - Liu X TI - [Observation of monoclonal antibody E4B7D5 inhibitory effect on leptospiral adherence using scanning electron microscope] LA - Chi MH - Animal MH - Antibodies, Bacterial/immunology MH - Antibodies, Monoclonal/*immunology MH - Bacterial Adhesion/*immunology MH - Bacterial Outer Membrane Proteins/*immunology MH - Cells, Cultured MH - English Abstract MH - Fibroblasts/cytology/microbiology MH - IgG/immunology MH - Leptospira interrogans/*immunology/ultrastructure MH - Mice MH - Mice, Inbred BALB C MH - Microscopy, Electron, Scanning MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 921112 DP - 1992 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 5-8 CY - CHINA IP - 1 VI - 23 JC - GEB AA - Author EM - 9301 AB - BALB/c mice were immunized intraperitoneally with outer envelopes of serogroup icterohaemorrhagiae lai serovar strain 017 leptospires. Monoclonal antibody (McAb) E4B7D5 against outer envelopes (IgG1, agglutinating titre 1:25,600) was produced by hybridoma technique. Passive immunoprotection experiments have demonstrated the immunoprotection of McAb E4B7D5 against strain 017 leptospires. Effect of McAb E4B7D5 on leptospiral adherence to the surface of normal human pulmonary embryonic fibroblasts was observed by using scanning electron microscope. The results indicated that the leptospiral adherence noted in various agglutinating titre McAb E4B7D5 groups was less frequent than that in the three control groups. It was concluded that the inhibitory effect of McAb E4B7D5 on leptospiral adherence may play a role in the immunoprotection. PMID- 1398625 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992 Mar;23(1):5-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 93013724 AU - Dong X AU - Dai B AU - Chai J TI - [Homology study of leptospires by molecular hybridization] LA - Chi MH - Blotting, Southern MH - DNA Probes MH - English Abstract MH - Leptospira/classification/*genetics MH - Leptospira interrogans/genetics MH - *Nucleic Acid Hybridization MH - Sequence Alignment MH - *Sequence Homology MH - Support, Non-U.S. Gov't RN - 0 (DNA Probes) PT - JOURNAL ARTICLE DA - 921112 DP - 1992 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 1-4 CY - CHINA IP - 1 VI - 23 JC - GEB AA - Author EM - 9301 AB - Nick translation and random primer labelling method were applied to prepare three genomic DNA probes from Leptospira interrogans strain 017, Leptospira biflexa strain Patoc I and Leptonema illini strain 3055, and then hybridized with DNA of 17 strains leptospires from different genus, species, serogroup and serovar. The results showed no homology between Leptospira and Leptonema, and only a low degree of homology between L. interrogans and L. biflexa but it showed a high degree of homology among L. interrogans. The study also proved the possibility to establish a DNA probe prepared from a single leptospira strain to detect different serovars. AD - The Institute of Genetics, Fudan University. PMID- 1398616 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1992 Mar;23(1):1-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 92377425 AU - Agaev IA TI - [Self-maintenance of foci of bovine leptospirosis] LA - Rus MH - Animal MH - Azerbaijan/epidemiology MH - Cattle MH - Cattle Diseases/*epidemiology MH - *Disease Reservoirs MH - English Abstract MH - Leptospirosis/*epidemiology/veterinary MH - Seasons PT - JOURNAL ARTICLE DA - 920923 DP - 1992 Mar IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 41-4 SB - M CY - USSR IP - 3 JC - Y9O AA - Author EM - 9211 AB - The relationship between the rate of cattle infection with leptospirosis and the total number of livestock at cattle-breeding farms has been established. The annual dynamics of this infection has been found to give two morbidity rises among the animals, occurring not due to their contacts with the natural foci of leptospirosis, but as a consequence of the animal vertical and horizontal "circulation". The mechanisms of self-maintenance of the foci of leptospirosis among cattle are discussed. PMID- 1387277 CU - 92 TT - Samopodderzhanie ochagov leptospiroza krupnogo rogatogo skota. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1992 Mar;(3):41-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 92186729 AU - Pinn TG TI - Leptospirosis in the Seychelles. LA - Eng MH - Adult MH - Aged MH - Alcohol Drinking/adverse effects MH - Animal MH - Creatine Kinase/blood MH - Disease Vectors MH - Female MH - Human MH - Male MH - Middle Age MH - Muscular Diseases/etiology MH - Pain/etiology MH - Prospective Studies MH - Rats MH - Seychelles/epidemiology MH - *Weil's Disease/diagnosis/epidemiology/physiopathology/therapy RN - EC 2.7.3.2 (Creatine Kinase) PT - JOURNAL ARTICLE DA - 920416 DP - 1992 Feb 3 IS - 0025-729X TA - Med J Aust PG - 163-7 SB - M SB - X CY - AUSTRALIA IP - 3 VI - 156 JC - M26 AA - Author EM - 9206 AB - OBJECTIVE: To ascertain the incidence of leptospirosis in the Seychelles, identify its sources, review diagnostic features and assess complications. DESIGN: A prospective survey over a two-year period 1988- 1990 of all cases diagnosed as having leptospirosis at Victoria Hospital, the main referral hospital for the Islands. RESULTS: Eighty cases were diagnosed on clinical grounds with serological confirmation in 58 (73%). Leptospira interrogans serovar icterohaemorrhagiae was identified in 27 (33%) and serovar autumnalis in 2 (3%), there was broad cross-reactivity in the other specimens. In a further 7 (9%), the diagnosis was confirmed at autopsy. Useful diagnostic aids were the finding of myalgia in 68 (85%) and a raised creatine phosphokinase (CPK) level in 61 (76%). CPK elevation was found to be a more reliable indicator of disease the earlier in the illness it was measured. Other important clinical signs are reviewed. Sixty (76%) were regular drinkers suggesting a relationship with home-brewed alcohol, 48 (60%) were in at-risk occupations; 13 (16%) deaths resulted. CONCLUSIONS: Leptospirosis in the Seychelles is likely to be rat borne. An annual incidence of 60 per 100,000 was found with significant mortality. Muscle tenderness and raised CPK levels were the most reliable early diagnostic aids. AD - Medical Department, Bundaberg Base Hospital. PMID- 1545718 SO - Med J Aust 1992 Feb 3;156(3):163-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 92157229 AU - Everard CO AU - Bennett S AU - Edwards CN AU - Nicholson GD AU - Hassell TA AU - Carrington DG AU - Everard JD TI - An investigation of some risk factors for severe leptospirosis on Barbados. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Agriculture MH - Barbados/epidemiology MH - Demography MH - Female MH - Human MH - Incidence MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Rain MH - Risk Factors MH - Rural Health MH - Sex Factors MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 920326 DP - 1992 Feb IS - 0022-5304 TA - J Trop Med Hyg PG - 13-22 SB - M CY - ENGLAND IP - 1 VI - 95 JC - KAV AA - Author EM - 9205 AB - Between November 1979 and the end of December 1986 (7.17 years), 248 cases of leptospirosis were confirmed among hospital patients on Barbados (mean 35 per year; range 25-57). Considering the 235 who were greater than or equal to 15 years of age, the annual incidence of leptospirosis was 19.2/100,000 population (14.0 for all age groups). There were 173 males and 62 females, and for cases aged 15-34 leptospirosis was 9.6 times more common in men than women. Among men, incidence increased fairly steadily with age, and an even steadier increase was apparent in women up to age 64, with some decline in later years. The incidence of disease was much higher among agricultural than other workers and the non-employed. Highest case numbers were recorded in the parishes of St Michael (65 or 28%) and Christ Church (36 or 15%), though the incidence was lowest in these two parishes (13.1/100,000 and 17.4/100,000, respectively). The highest incidence rates were in St Andrew and St Joseph (50.2 and 36.1/100,000, respectively). The incidence in areas with rainfall greater than or equal to 1600 mm (32.6/100,000) was nearly twice that in areas with rainfall less than 1600 mm (17.3/100,000). There is a clear link between cases of severe disease and recent rainfall. Using 134 patients greater than or equal to 15 years of age with fever due to other illnesses as controls, a higher proportion of cases than controls came from rural areas. The risk of contracting leptospirosis was increased for all categories of manual workers relative to the group at lowest risk (non-manual indoor workers). Sugar-cane workers were five times more likely to contract leptospirosis than were non-manual indoor workers, while those whose families minded livestock were 2.5 times more likely, and those with rodents in their garden/yard were 1.8 times more likely to do so. Other risk factors examined did not show significant associations with the disease. Despite increasing mechanization and the use of more protective clothing, agricultural workers are still at high risk from leptospirosis. The annual range of cases is likely to stay much as it is in the foreseeable future. AD - Leptospira Laboratory, St Michael, Barbados. PMID- 1740814 SO - J Trop Med Hyg 1992 Feb;95(1):13-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 92337543 AU - Skilbeck NW AU - Lyon M AU - Stallman N TI - Genetic diversity among Australian and New Zealand isolates of Leptospira interrogans serovar pomona. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/microbiology MH - Deoxyribonuclease EcoRI MH - DNA, Bacterial/*analysis MH - Genotype MH - Human MH - Leptospira interrogans/classification/*genetics MH - Leptospirosis/microbiology/*veterinary MH - New South Wales MH - New Zealand MH - Restriction Mapping MH - Swine MH - Swine Diseases/microbiology MH - *Variation (Genetics) MH - Victoria MH - Weil's Disease/*microbiology RN - EC 3.1.21.- (Deoxyribonuclease EcoRI) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 920819 DP - 1992 Feb IS - 0005-0423 TA - Aust Vet J PG - 29-30 SB - M CY - AUSTRALIA IP - 2 VI - 69 JC - 9IE AA - Author EM - 9210 AB - Restriction endonuclease analysis of 16 Australian and 4 New Zealand isolates of Leptospira interrogans serovar pomona showed that they could be divided into 3 genetic groups. Most of the isolates closely resembled the serovar kennewicki reference strain, and they all differed from the reference strain of serovar pomona. Based on these findings, it is suggested that vaccine manufacturers re-evaluate their choice of serovar pomona vaccine strain. AD - Department of Agriculture, Regional Veterinary Laboratory, Bairnsdale, Victoria. PMID- 1632725 SO - Aust Vet J 1992 Feb;69(2):29-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 92257564 AU - Shi M TI - [A quick method for the diagnosis of leptospirosis] LA - Chi MH - Antigens, Bacterial/*blood MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay/methods MH - Human MH - Leptospira interrogans/*immunology MH - Weil's Disease/*diagnosis RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 920618 DP - 1992 Feb IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 45-6 CY - CHINA IP - 1 VI - 13 JC - CQG AA - Author EM - 9208 AB - Seventy-nine sero-samples from patients with leptospirosis were tested by dot-ELISA and microscopical agglutination test (MAT). Results showed that the accordance rate was 96.19%. 20 sero-samples obtained from healthy people, 4 from hepatitis B(HBV) and 4 from epidemic hemorrhage fever (EHF) were negative by dot-ELISA. We believe dot-ELISA is a simple, rapid method which can be used to diagnose those patients with leptospirosis. AD - Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing. PMID- 1581955 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1992 Feb;13(1):45-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 92251733 AU - Sinclair DG AU - World MJ TI - Leptospirosis--a cause for concern? [see comments] LA - Eng MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Great Britain MH - Heat Exhaustion/*diagnosis MH - Human MH - Male MH - *Military Personnel MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 920610 DP - 1992 Feb IS - 0035-8665 TA - J R Army Med Corps PG - 40-2 SB - M CY - ENGLAND IP - 1 VI - 138 JC - JV6 AA - Author EM - 9208 AB - A severe case of Weil's disease is presented. The particular relevance of this condition to the Armed Forces and Service physicians is discussed, together with methods of diagnosis. AD - Department of Medicine, Cambridge Military Hospital, Aldershot, Hants. CM - Comment in: J R Army Med Corps 1992 Jun;138(2):102 CM - Comment in: J R Army Med Corps 1992 Jun;138(2):102-3 RO - M:LC1 RO - M:LC1 PMID- 1578434 LR - 930111 SO - J R Army Med Corps 1992 Feb;138(1):40-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 92248244 AU - Khisamov GZ AU - Morozova NK TI - Phospholipid catabolism enzymes of leptospires. LA - Eng MH - Chromatography, Thin Layer MH - Hydrogen-Ion Concentration MH - Leptospira/*enzymology MH - Leptospira canicola/*enzymology MH - Phospholipases/chemistry/*metabolism MH - Phospholipids/*metabolism MH - Substrate Specificity RN - EC 3.1.- (Phospholipases) RN - 0 (Phospholipids) PT - JOURNAL ARTICLE DA - 920611 DP - 1992 Feb IS - 0934-8840 TA - Int J Med Microbiol Virol Parasitol Infect Dis PG - 347-55 SB - M CY - GERMANY IP - 3 VI - 276 JC - BD7 AA - Author EM - 9208 AB - Phospholipase A2, C, D activities of pathogenic (VGNCI-3, HS-26) and saprophytic (K-1028, G-80) strains of leptospires were determined. The strains used synthesized intracellular and extracellular forms of these esterases. To a considerable degree the endophospholipase activity was associated with the membrane structures. Differences in substrate specificity, Km, Vmax pH optimum values between exophospholipases of pathogenic and saprophytic leptospires used in the experiments are demonstrated. AD - Microbiology Laboratory, Medical Faculty, Patrice Lumumba Friendship University, Moscow, Russia. PMID- 1576404 SO - Int J Med Microbiol Virol Parasitol Infect Dis 1992 Feb;276(3):347-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 92222186 AU - Moreno RJ AU - Weisman J AU - Waller S TI - Neuroretinitis: an unusual presentation of ocular toxoplasmosis. LA - Eng MH - Adult MH - Antibiotics/therapeutic use MH - Antibodies, Protozoan/analysis MH - Case Report MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescein Angiography MH - Fundus Oculi MH - Human MH - Male MH - Optic Neuritis/drug therapy/*parasitology MH - Prednisone/therapeutic use MH - Retinitis/drug therapy/*parasitology MH - *Toxoplasmosis, Ocular/drug therapy MH - Visual Acuity RN - 0 (Antibiotics) RN - 0 (Antibodies, Protozoan) RN - 53-03-2 (Prednisone) PT - JOURNAL ARTICLE DA - 920514 DP - 1992 Feb IS - 0003-4886 TA - Ann Ophthalmol PG - 68-70 SB - M CY - UNITED STATES IP - 2 VI - 24 JC - 5PA AA - Author EM - 9207 AB - Neuroretinitis is a clinical condition usually seen in young healthy adults that is characterized by rapid profound unilateral loss of vision. Funduscopic findings include swollen disc, splinter hemorrhages, and macular star. Catscratch fever and leptospirosis have been suggested as possible etiologies in this condition. We report a case of a patient with neuroretinitis whose only laboratory abnormality was an elevated enzyme-linked immunosorbent assay immunoglobulin G Toxoplasma titer. The patient responded favorably to treatment with clindamycin, triple sulfa, and systemic corticosteroids. We recommended toxoplasmic serology be added to the workup of patients with neuroretinitis. AD - Department of Ophthalmology, Wilford Hall USAF Medical Center, Lackland AFB, Texas 78236-5300. PMID- 1562128 SO - Ann Ophthalmol 1992 Feb;24(2):68-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 92213935 AU - Chappel RJ AU - Prime RW AU - Millar BD AU - Mead LJ AU - Jones RT AU - Adler B TI - Comparison of diagnostic procedures for porcine leptospirosis. LA - Eng MH - Abattoirs MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/blood MH - Comparative Study MH - DNA, Bacterial/analysis MH - Immunoenzyme Techniques MH - Immunohistochemistry MH - Leptospira interrogans/genetics/immunology/*isolation & purification MH - Leptospirosis/diagnosis/pathology/*veterinary MH - Liver/microbiology/*pathology MH - Nucleic Acid Hybridization MH - Sensitivity and Specificity MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*diagnosis/pathology RN - 0 (Antibodies, Bacterial) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 920507 DP - 1992 Feb IS - 0378-1135 TA - Vet Microbiol PG - 151-63 SB - M CY - NETHERLANDS IP - 2-3 VI - 30 JC - XBW AA - Author EM - 9207 AB - Kidneys and matched serum samples were obtained from 368 pigs slaughtered at three Victorian abattoirs, and originating from 42 farms. Macroscopic lesions (white spots) were observed on 102 of the kidneys. Serum samples were tested by the microscopic agglutination test (MAT) and by an IgM enzyme immunoassay (EIA). Kidneys were cultured for leptospires, examined histologically after Warthin-Starry silver staining and after immunogold silver staining (IGSS), and tested for leptospiral DNA by DNA hybridization. Forty-four infected pigs were identified by culture or immunogold silver staining of kidneys or by high MAT titres (greater than or equal to 1024). Infection was demonstrated in 7.5% of visibly normal kidneys, in 23.5% of kidneys with white spots, and in 48% of kidneys with large white spots, of 1 cm diameter or greater. The apparent (maximum) sensitivities of diagnostic procedures for detecting infection were as follows: MAT (at a titre of either 64 or 1024) 95%; IgM EIA 82%; culture 61%; presence of white spots 55%; IGSS 52%; presence of large white spots 30%; Warthin-Starry silver staining 20%. IGSS, Warthin-Starry staining and DNA hybridization all appeared to be highly specific. Of 22 kidney sections identified as positive by IGSS, 13 showed intact leptospires, and these kidneys were all culture-positive. Nine others showed leptospiral antigen in the kidney tubules but no intact leptospires. Only five of these kidneys were culture-positive. AD - Department of Agriculture, Victorian Institute of Animal Science, Attwood, Australia. PMID- 1557894 SO - Vet Microbiol 1992 Feb;30(2-3):151-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 92376831 AU - Zieris H AU - Wilhelm A TI - [Infection with Leptospira interrogans, serovar mozdok, in cattle] LA - Ger MH - Abortion, Veterinary/*microbiology/pathology MH - Animal MH - Case Report MH - Cattle MH - Cattle Diseases/*microbiology/pathology MH - English Abstract MH - Female MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/pathology/*veterinary MH - Male MH - Pregnancy PT - JOURNAL ARTICLE DA - 920922 DP - 1992 Feb IS - 0303-6286 TA - Tierarztl Prax PG - 33-7 SB - M CY - GERMANY IP - 1 VI - 20 JC - VS4 AA - Author EM - 9211 AB - In East Germany the same serovar, Leptospira mozdok, of the Pomona serogroup is found in cattle as well as in swine populations (Zieris 1989). Nowadays cases of bovine leptospirosis caused by infection with L. pomona have no significance. There are marked epizoological differences between infection with L. mozdok and L. pomona. The main source of infection with L. mozdok for cattle is the black striped field mouse (Apodemus agrarius). Secondary homonomous transmission occurs among the cattle. The clinical course of both infections is the same--including peracute, acute and chronic forms. Important prophylactic measures are effective rodent control and optimising hygiene conditions both in housing and on pasture. Veterinarians in abattoirs must consider leptospirosis in the differential diagnosis in cases with icteric signs, especially when the meat is derived from emergency slaughter. AD - Staatlichen Veterinar- und Lebensmitteluntersuchungsamt Cottbus. PMID- 1509476 TT - Infektion mit Leptospira interrogans, Serovar mozdok, beim Rind. EA - A SO - Tierarztl Prax 1992 Feb;20(1):33-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [205 medline neighbors] UI - 92298473 AU - Fukunaga M AU - Mifuchi I AU - Yanagihara Y AU - Okuzako N TI - Comparison of flanking regions of the 5S ribosomal ribonucleic acid genes in Leptospira biflexa and Leptospira interrogans. LA - Eng MH - Base Sequence MH - Blotting, Southern MH - Comparative Study MH - DNA, Ribosomal/genetics MH - Genes, Bacterial MH - Leptospira/*genetics MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - Restriction Mapping MH - RNA, Bacterial/genetics MH - RNA, Ribosomal, 5S/*genetics RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal, 5S) PT - JOURNAL ARTICLE DA - 920721 DP - 1992 Feb IS - 0009-2363 TA - Chem Pharm Bull (Tokyo) PG - 544-6 CY - JAPAN IP - 2 VI - 40 JC - CZP AA - Author EM - 9209 AB - One of the genes encoding the 5S ribosomal ribonucleic acid (rRNA) for the Leptospira biflexa strain Patoc I was isolated and sequenced. The physical maps of the 5S rRNA genes in Leptospira were constructed. The strains of Leptospira biflexa had two genes on their chromosome; these two 5S rRNA genes were located several kb apart and sequences flanking these genes were divergent. In contrast to saprophytic leptospires, maps in parasitic leptospires that had only one gene for 5S rRNA on their genome were highly conserved and the physical maps of the genes in almost all strains were similar. AD - Faculty of Pharmacy and Pharmaceutical Sciences, University of Fukuyama, Hiroshima, Japan. PMID- 1376643 CU - 95 SI - GENBANK/D90255 SI - GENBANK/S53720 SI - GENBANK/S47136 SI - GENBANK/S47137 SI - GENBANK/S47164 SI - GENBANK/S47165 SI - GENBANK/S47166 SI - GENBANK/S47167 SI - GENBANK/S47168 SI - GENBANK/S72771 SO - Chem Pharm Bull (Tokyo) 1992 Feb;40(2):544-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 92209988 AU - Hookey JV TI - Detection of Leptospiraceae by amplification of 16S ribosomal DNA. LA - Eng MH - Base Sequence MH - DNA, Bacterial/genetics MH - DNA, Ribosomal/*genetics MH - Leptospira/genetics/*isolation & purification MH - Leptospiraceae/genetics/*isolation & purification MH - Molecular Sequence Data MH - Oligodeoxyribonucleotides MH - *Polymerase Chain Reaction MH - RNA, Bacterial/genetics MH - RNA, Ribosomal, 16S/*genetics MH - Sensitivity and Specificity MH - Weil's Disease/microbiology RN - 0 (DNA, Bacterial) RN - 0 (DNA, Ribosomal) RN - 0 (Oligodeoxyribonucleotides) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 920506 DP - 1992 Jan 15 IS - 0378-1097 TA - FEMS Microbiol Lett PG - 267-74 SB - M CY - NETHERLANDS IP - 3 VI - 69 JC - FML AA - Author EM - 9207 AB - The polymerase chain reaction (PCR) was developed to detect Leptospiraceae. Primers were used to amplify 1 631 base-pair (bp) 5'- region of 16S rDNA. Representative strains from the species, Leptospira interrogans sensu stricto, L. borgpetersenii, L. noguchii, L. santarosai, L. weilii, L. inadai, L. meyeri and the single member strain of Leptonema were amplified. In contrast, strains representing the saprophytic species. L. biflexa, L. wolbachii and L. parva were not amplified. There was no PCR product from 23 phylogenetically unrelated species of bacteria. As little as 10-1 pg of purified DNA and as few as 10-1 leptospires could be detected using the PCR analysis. Isolates of leptospires from clinical sources gave a positive PCR band, but those from surface waters did not. AD - PHLS Leptospira Reference Laboratory, FAO/WHO Collaborating Centre, County Hospital, Hereford, U.K. PMID- 1372872 CU - 95 SO - FEMS Microbiol Lett 1992 Jan 15;69(3):267-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 92180281 AU - McCandlish IA AU - Cornwell HJ AU - Thompson H AU - Nash AS AU - Lowe CM TI - Distemper encephalitis in pups after vaccination of the dam. LA - Eng MH - Animal MH - Animals, Suckling MH - Antibodies, Viral/blood MH - Distemper/*etiology/pathology/transmission MH - Distemper Virus, Canine/*immunology MH - Dog Diseases/*etiology/pathology MH - Dogs MH - Encephalomyelitis, Acute Disseminated/etiology/*veterinary MH - Female MH - Immunity, Maternally-Acquired MH - Immunization, Secondary/adverse effects/*veterinary MH - Neutralization Tests MH - Viral Vaccines/*adverse effects/immunology RN - 0 (Antibodies, Viral) RN - 0 (Viral Vaccines) PT - JOURNAL ARTICLE DA - 920407 DP - 1992 Jan 11 IS - 0042-4900 TA - Vet Rec PG - 27-30 SB - M CY - ENGLAND IP - 2 VI - 130 JC - XBS AA - Author EM - 9206 AB - A five-year-old labrador bitch which had whelped 10 pups three days previously was given booster vaccination against distemper, adenovirus, parvovirus, parainfluenzavirus and leptospirosis. Eighteen days later, signs of central nervous system disease developed in some of the pups, five of which were ultimately euthanased. The cause of the nervous disease was found to be canine distemper, and serological studies showed that the infection was limited to some members of the litter, suggesting that the vaccinal rather than a field virus was more likely to have been responsible. AD - Department of Veterinary Pathology, University of Glasgow Veterinary School. PMID- 1347434 CU - 94 SO - Vet Rec 1992 Jan 11;130(2):27-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [10 protein links] [9 nucleotide links] [205 medline neighbors] UI - 92129685 AU - Picken RN TI - Polymerase chain reaction primers and probes derived from flagellin gene sequences for specific detection of the agents of Lyme disease and North American relapsing fever. LA - Eng MH - Amino Acid Sequence MH - Animal MH - Base Sequence MH - Borrelia/classification/*genetics MH - Borrelia burgdorferi/genetics MH - Cloning, Molecular MH - Comparative Study MH - *DNA Probes MH - Flagellin/*genetics MH - *Genes, Structural, Bacterial MH - Human MH - Lyme Disease/diagnosis/*microbiology MH - Mice MH - Molecular Sequence Data MH - North America MH - Oligonucleotide Probes MH - *Polymerase Chain Reaction MH - Relapsing Fever/diagnosis/*microbiology MH - Species Specificity RN - 0 (DNA Probes) RN - 0 (Oligonucleotide Probes) RN - 12777-81-0 (Flagellin) PT - JOURNAL ARTICLE DA - 920302 DP - 1992 Jan IS - 0095-1137 TA - J Clin Microbiol PG - 99-114 SB - M CY - UNITED STATES IP - 1 VI - 30 JC - HSH AA - Author EM - 9205 AB - By cloning and sequencing the flagellin gene of Borrelia hermsii and comparing this sequence with that of the corresponding gene from B. burgdorferi, I identified a central region within the two genes which showed a reduced level of sequence similarity. Oligonucleotide sequences selected from this region produced species-specific amplimers when used in polymerase chain reaction experiments. Thus, primers derived from the B. burgdorferi sequence amplified a 276-bp fragment from 22 strains of B. burgdorferi of diverse geographic origin but not from 5 strains of B. hermsii, 5 other Borrelia species, 16 Treponema, Leptospira, and Spirochaeta species, or representatives of 10 other bacterial genera. However, when the amplified fragments were tested for hybridization with an oligonucleotide probe derived from the nonhomologous region, seven strains from either Germany or Switzerland did not hybridize. Cloning and sequencing of the amplified fragments from these strains revealed that the 22 strains of B. burgdorferi tested could be divided into three groups based on the nucleic acid sequence of the central region of the flagellin gene. With this information, oligonucleotide probes that hybridized to the amplified fragments and were able to differentiate the three groups of B. burgdorferi were designed. The corresponding primers, derived from the B. hermsii gene sequence, were tested for their ability to amplify DNA from this collection of strains. Although no amplification was obtained with representatives of the three groups of B. burgdorferi or various Treponema, Leptospira, and Spirochaeta species, amplification was obtained with the five other Borrelia species (B. parkeri, B. turicatae, B. crocidurae, B. anserina, and B. coriaceae) in addition to the five strains of B. hermsii. Sequencing of the amplified fragments from one strain of B. hermsii as well as B. parkeri and B. turicatae allowed the design of oligonucleotide probes that were able to differentiate the three species of North American relapsing fever spirochetes into two separate groups. These studies suggest that there is sufficient diversity within the flagellin gene sequences of closely related Borrelia species to differentiate them into groups and to pursue taxonomic studies both within and between species. AD - Pandex Division, Baxter Diagnostics, Inc., Mundelein, Illinois 60060. PMID- 1734073 CU - 93 SI - GENBANK/M33839 SI - GENBANK/M34710 SI - GENBANK/M67456 SI - GENBANK/M67457 SI - GENBANK/M67458 SI - GENBANK/M67459 SI - GENBANK/M67460 SI - GENBANK/M67461 SI - GENBANK/M67462 SI - GENBANK/M86838 SI - GENBANK/S40279 SO - J Clin Microbiol 1992 Jan;30(1):99-114 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 92352690 AU - Wyler DJ TI - Evaluation of cryptic fever in a traveler to Africa. LA - Eng MH - Africa MH - Bacterial Infections/*complications MH - Diagnosis, Differential MH - Fever of Unknown Origin/*etiology MH - Hemorrhagic Fevers, Viral/*complications MH - Human MH - Leptospirosis/complications MH - Malaria/complications MH - Meningococcal Infections/complications MH - Parasitic Diseases/*complications MH - Rickettsiaceae Infections/complications MH - Schistosomiasis/complications MH - *Travel MH - Typhoid/complications PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, ACADEMIC DA - 920910 DP - 1992 IS - 0195-3842 TA - Curr Clin Top Infect Dis PG - 329-47 SB - M CY - UNITED STATES VI - 12 JC - AH0 EM - 9211 RF - 72 PMID- 1642803 SO - Curr Clin Top Infect Dis 1992;12:329-47 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 92292927 AU - Gendron Y AU - Prieur J AU - Gaufroy X AU - Gras C TI - [Leptospirosis in French Polynesia: 120 case reports] LA - Fre MH - Adult MH - English Abstract MH - Female MH - Human MH - Incidence MH - Length of Stay/statistics & numerical data MH - Leptospirosis/classification/drug therapy/*epidemiology MH - Male MH - Middle Age MH - Patient Admission/statistics & numerical data MH - Penicillin G/administration & dosage/therapeutic use MH - Polynesia/epidemiology MH - Sex Factors RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 920716 DP - 1992 Jan-Mar IS - 0025-682X TA - Med Trop (Mars) PG - 21-7 SB - M CY - FRANCE IP - 1 VI - 52 JC - MHQ AA - Author EM - 9209 AB - Because of its clinical polymorphism and the difficulties to made a bacteriological and/or serological diagnosis, leptospirosis is an affection always non-detected. Nevertheless it is daily met affection in French Polynesia. Based on a homogenous series of 120 observations gathered from 1984 to 1990, all of them bacteriologically and/or serologically confirmed, we studied the different clinical and evolutive features of that disease. Fever is present in 91.6 p.c., cephalgia in 79.16 p.c. and myalgia in 70.83 p.c. Admission was necessary once out of four times. The four syndromes we observed in Tahiti are: infections syndrome, meningeal syndrome (30 p.c.) associated to an hyperproteinic grade in the C.S.F. (40 p.c.) and a lymphocytic reaction (60 p.c.). Liver syndrome, with hepatalgia (58.33 p.c.) and pain at the mass motion of liver (65 p.c.), that is an important sign in the local context; jaundice (28.33 p.c.) on the presence of which we must not based a diagnosis of leptospirosis: Biological renal syndrome displayed by transitory renal insufficiency with proteinuria, hematuria and leucocyturia. Neurological complications are mainly of encephalitic manifestations (5.8 p.c.). Hemorrhagic syndrome is expressed in digestive hemorrhage (8.33 p.c.) epistaxis (6.66 p.c.) and hemoptysis (6.66 p.c.). Cardiovascular manifestations are expressed in collapsus in 5.83 of the cases. Pulmonary abnormalities are frequent: cough (26.66 p.c.) and non specific X Ray image (19.16 p.c.). All patients are treated by Penicillin G (10 to 20 millions per day) by parenteral route with enteral alternative for an average of 10 days. Recovery was fast (7 to 10 days). In 65.8 p.c., slower in 15 p.c. (15 to 20 days); failure at first stage was observed in 10 p.c. of the cases, and relapse at medium or long term occurred under treatment in 8 cases (6.66 p.c.). Three dead were deplored (mortality 2.5 p.c.). AD - Medecin des Hopitaux, Clinique Cardella Papeete, Polynesie Francaise. PMID- 1602950 TT - Les leptospiroses en Polynesie Francaise: etude de 120 observations. EA - A SO - Med Trop (Mars) 1992 Jan-Mar;52(1):21-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 92224949 AU - Caruso G AU - Rigoli R AU - Conz P AU - Cinco M AU - Banfi E AU - de Lalla F TI - Human leptospirosis in the Vicenza area, Italy [letter] LA - Eng MH - Adult MH - Agglutination Tests MH - Ampicillin/administration & dosage/*therapeutic use MH - Drug Administration Schedule MH - Female MH - Human MH - Italy/epidemiology MH - Leptospira/isolation & purification MH - Leptospirosis/drug therapy/*epidemiology MH - Male MH - Middle Age MH - Penicillin G/administration & dosage/*therapeutic use RN - 61-33-6 (Penicillin G) RN - 69-53-4 (Ampicillin) PT - LETTER DA - 920520 DP - 1992 Jan IS - 0934-9723 TA - Eur J Clin Microbiol Infect Dis PG - 77-9 SB - M CY - GERMANY IP - 1 VI - 11 JC - EM5 EM - 9207 PMID- 1563391 SO - Eur J Clin Microbiol Infect Dis 1992 Jan;11(1):77-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 92208047 AU - Bolin CA AU - Cassells JA TI - Isolation of Leptospira interrogans serovars bratislava and hardjo from swine at slaughter. LA - Eng MH - Abattoirs MH - Animal MH - Fallopian Tubes/microbiology MH - Female MH - Genitalia, Female/*microbiology MH - Kidney/*microbiology MH - Leptospira interrogans/classification/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Swine MH - Swine Diseases/*microbiology MH - Uterus/microbiology PT - JOURNAL ARTICLE DA - 920507 DP - 1992 Jan IS - 1040-6387 TA - J Vet Diagn Invest PG - 87-9 SB - M CY - UNITED STATES IP - 1 VI - 4 JC - A2D EM - 9207 AD - Leptospirosis and Mycobacteriosis Research Unit, USDA, Agriculture Research Service, Ames, IA 50010. PMID- 1554777 SO - J Vet Diagn Invest 1992 Jan;4(1):87-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 92208030 AU - Whipple DL AU - Kapke PA AU - Andersen PR TI - Comparison of a commercial DNA probe test and three cultivation procedures for detection of Mycobacterium paratuberculosis in bovine feces. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis/microbiology MH - Centrifugation MH - Comparative Study MH - DNA Probes MH - DNA, Bacterial/*analysis MH - Feces/*microbiology MH - Mycobacterium tuberculosis/genetics/*isolation & purification MH - Paratuberculosis/*diagnosis/microbiology MH - Polymerase Chain Reaction MH - Reagent Kits, Diagnostic/veterinary MH - Sensitivity and Specificity RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) RN - 0 (Reagent Kits, Diagnostic) PT - JOURNAL ARTICLE DA - 920507 DP - 1992 Jan IS - 1040-6387 TA - J Vet Diagn Invest PG - 23-7 SB - M CY - UNITED STATES IP - 1 VI - 4 JC - A2D AA - Author EM - 9207 AB - Diagnosis of paratuberculosis using the IDEXX DNA probe test and 3 methods for cultivation of Mycobacterium paratuberculosis from fecal specimens were compared. Twenty-one of 170 fecal specimens were DNA probe test positive, whereas 35 specimens were positive by 1 or more of the cultivation methods evaluated. Four specimens were DNA probe test positive but were negative by fecal culture. The probe test detected M. paratuberculosis DNA in 62.9% of the specimens positive by a sedimentation culture method, in 56.6% of those positive by a centrifugation culture method, and in 65.4% of the specimens positive by the Cornell culture method. Specificity of the DNA probe test was approximately 97% relative to all culture methods. Generally, the probe test detected M. paratuberculosis DNA in fecal specimens from animals shedding at least 10(4) M. paratuberculosis colony forming units per gram of feces. Although the probe test did not detect all of the cattle shedding M. paratuberculosis, it was possible to identify cattle shedding the greatest number of organisms in 3 days compared with a minimum of 6 weeks required for positive culture results. The centrifugation method resulted in the most isolations of M. paratuberculosis after 12 weeks of incubation. However, contamination also was greatest when the centrifugation method was used. Contamination was best controlled using the Cornell method. The sedimentation method was the least time consuming and yielded results similar to those of the other 2 methods. AD - Leptospirosis/Mycobacteriosis Research Unit, National Animal Disease Center, Ames, IA 50010. PMID- 1554765 CU - 92 SO - J Vet Diagn Invest 1992 Jan;4(1):23-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 92383554 AU - Terpstra WJ TI - Serodiagnosis of bacterial diseases: problems and developments. LA - Eng MH - Antibodies, Bacterial/analysis MH - Bacterial Infections/*diagnosis MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Leptospirosis/diagnosis MH - *Serodiagnosis MH - Serotyping RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 920929 DP - 1992 IS - 0301-6323 TA - Scand J Immunol Suppl PG - 91-5 SB - X CY - ENGLAND VI - 11 JC - UC7 AA - Author EM - 9212 AB - Serodiagnosis is useful when pathogens cannot be detected quickly or easily by conventional methods or have been eliminated by the patient. Taking the example of leptospirosis, the microscopic agglutination test to detect specific antibodies after leptospires have disappeared from the patient's bloodstream is of unsurpassed reliability. Unfortunately the test is used mainly in specialized laboratories that can culture leptospires to serve as live antigens. Freeze-dried leptospires may allow the application of the test on a wide scale. The ELISA is useful for the detection of IgM antibodies in humans as a sign of current or recent infection. ELISA results must be confirmed by the microscopic agglutination test. A simplified easy-to-read ELISA using broadly reactive antigen for the detection of all types of leptospires might be useful for a quick detection of acute human leptospirosis. Using an appropriate antigenic preparation the ELISA is useful for the detection of antibodies in animals, e.g. cattle. As for pathogen detection, DNA- based methods such as PCR are promising for an early, quick and specific diagnosis. Antigenic analysis by monoclonal antibodies and genetic analysis by restriction fragment length polymorphism are for the time being complementary methods for the characterization of leptospiral isolates. AD - N. H. Swellengrebel Laboratory of Tropical Hygiene, Royal Tropical Institute, Amsterdam, The Netherlands. RO - M:CNR PMID- 1514058 LR - 940202 SO - Scand J Immunol Suppl 1992;11:91-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 93134915 AU - Terpstra WJ TI - Typing leptospira from the perspective of a reference laboratory. LA - Eng MH - Comparative Study MH - DNA/analysis MH - Leptospira/*classification MH - Phylogeny MH - Serotyping/*methods RN - 9007-49-2 (DNA) PT - JOURNAL ARTICLE DA - 930218 DP - 1992 IS - 0065-1362 TA - Acta Leiden PG - 79-87 CY - NETHERLANDS IP - 2 VI - 60 JC - 0WI AA - Author EM - 9304 AB - Leptospirosis is caused by different leptospiral variants. Analysis by cross agglutination absorption tests (CAAT) led to the definition of entities called serovars to distinguish between leptospires on sub- species level, and to the designation of reference strains representing serovars. For decades CAAT has been used to classify leptospires and now approximately 200 serovars have been recognized. In the last few years, it has become increasingly more clear that the serovar concept is no longer fully satisfactory as it may fail to adequately define epidemiologically important entities. In addition, CAAT is too cumbersome and time-consuming for routine typing. Various methods have been developed based on antigenic or genetic analysis with the purpose to supplement or to replace the CAAT. Most of these methods are still in an experimental state. It is to be expected that a typing method based on genomic analysis will eventually become most important. Such a new method should have considerable advantages in order to be acceptable for the development of a new classification system replacing the system based on serovars, which is widely accepted and in many respects still satisfactory. From the new methods, analysis of leptospiral DNA fragment length after digestion with restriction enzymes (REA) has been widely used and proven to be useful for typing. Pending the development of new typing methods that have clear advantages and may lead to a new classification system, it is suggested that the classification system based on serovars is maintained and that REA is added to each description of a new serovar. AD - N.H. Swellengrebel Laboratory of Tropical Hygiene, Royal Tropical Institute, Amsterdam. PMID- 1485498 SO - Acta Leiden 1992;60(2):79-87 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 93063652 AU - Magaldi AJ AU - Yasuda PN AU - Kudo LH AU - Seguro AC AU - Rocha AS TI - Renal involvement in leptospirosis: a pathophysiologic study. LA - Eng MH - Animal MH - Female MH - Furosemide/pharmacology MH - Guinea Pigs MH - Kidney Concentrating Ability MH - Kidney Tubules/*physiopathology MH - Leptospirosis/*physiopathology MH - Male MH - Potassium/metabolism MH - Sodium/metabolism MH - Support, Non-U.S. Gov't MH - Urea/metabolism MH - Vasopressins/pharmacology MH - Water-Electrolyte Balance RN - 0 (Vasopressins) RN - 54-31-9 (Furosemide) RN - 57-13-6 (Urea) RN - 7440-09-7 (Potassium) RN - 7440-23-5 (Sodium) PT - JOURNAL ARTICLE DA - 921204 DP - 1992 IS - 0028-2766 TA - Nephron PG - 332-9 SB - M CY - SWITZERLAND IP - 3 VI - 62 JC - NW8 AA - Author EM - 9302 AB - The kidney involvement in leptospirosis appears to be a special form of acute renal failure due to a higher frequency of polyuric forms and the presence of hypokalemia with an elevated urinary fractional excretion of potassium. Using a clearance technique, we detected higher fractional urinary potassium excretion in leptospirotic guinea pigs (26.5 +/- 4.7%) than in normal animals (14.1 +/- 2.8%, p < 0.05). After blocking distal NaCl reabsorption with furosemide, it was observed that in leptospirotic animals both fractional sodium excretion (40.0 +/- 7.4%) and fractional potassium excretion (136.3 +/- 32.7%) were higher than in normal animals (20.4 +/- 3.8%, p < 0.05, and 43.6 +/- 9.0%, p < 0.05, respectively). Microperfusion studies showed that the normal and leptospirotic medullary thick ascending limb had both identical transepithelial potential difference (+3.7 +/- 0.4 vs. 3.9 +/- 0.2 mV) and relative sodium-to-chloride permeability. The same technique showed that the osmotic water permeability (Posm; 0.9 +/- 0.4 x 10(-5) cm/s.atm) and diffusional permeability (34.7 +/- 6.6 x 10(-5) cm/s) observed in the leptospirotic inner medullary collecting duct (IMCD) in the presence of vasopressin were unchanged, as was also the case for urea permeability (3.74 +/- 0.7 x 10(-5) cm/s). These data show that acute renal failure in leptospirosis is characterized by tubular changes leading to potassium secretion probably due to a decrease in proximal sodium reabsorption. Furthermore, the inability to concentrate urine evidenced by the low P(o)sm present in leptospirotic animals is due, at least in part, to IMCD resistance to vasopressin. AD - Laboratorio de Pesquisa Basica da Unidade de Doencas Renais, Faculdade de Medicina, Universidade de Sao Paulo, Brasil. PMID- 1436348 SO - Nephron 1992;62(3):332-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 93018603 AU - Petchclai B AU - Hiranras S AU - Kunakorn M AU - Potha U AU - Liemsuwan C TI - Enzyme-linked immunosorbent assay for leptospirosis immunoglobulin M specific antibody using surface antigen from a pathogenic Leptospira: a comparison with indirect hemagglutination and microagglutination tests. LA - Eng MH - Agglutination Tests/*standards MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay/*standards MH - Evaluation Studies MH - Hemagglutination Tests/*standards MH - Hospitals, University MH - Human MH - Leptospirosis/*blood/epidemiology/immunology MH - Sensitivity and Specificity MH - Serotyping MH - Thailand/epidemiology PT - JOURNAL ARTICLE DA - 921119 DP - 1992 Jan IS - 0125-2208 TA - J Med Assoc Thai PG - 203-8 CY - THAILAND VI - 75 Suppl 1 JC - IZR AA - Author EM - 9301 AB - A search for a sensitive and specific test for human leptospirosis was made by enzyme-linked immunosorbent assay for immunoglobulin M specific antibody (IgM ELISA) using a surface antigen from L.interrogans serovar bataviae, L. interrogans serovar pyrogenes and L.interogans serovar icterohaemorrhagiae. The IgM ELISA tests using each of the three antigens were evaluated in 103 sera primarily positive by microagglutination test (MA). Optical density of these IgM ELISA tests showed good correlation. The IgM ELISA using antigen from serovar bataviae was compared with MA and indirect hemagglutination (IHA) in 20 sera primarily positive by IHA, and 103 sera primarily positive by MA. IgM ELISA and IHA using antigen prepared from serovar bataviae in 103 sera positive for MA had a sensitivity of 98.06 and 92.23 per cent respectively. In 20 sera primarily positive by IHA, IgM ELISA and MA showed sensitivity of 80 and 45 per cent respectively. The surface antigen used in IgM ELISA is broadly specific making IgM ELISA a sensitive and specific test for human leptospirosis. IHA agreed more with IgM ELISA in comparison to MA. As MA is not sensitive for early infection, IHA and IgM ELISA should be in routine use in general laboratories. AD - Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand. PMID- 1402466 SO - J Med Assoc Thai 1992 Jan;75 Suppl 1:203-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 92241441 AU - Nuti M AU - Amaddeo D AU - Autorino GL AU - Crovatto M AU - Crucil C AU - Ghionni A AU - Giommi M AU - Salvati F AU - Santini GF TI - Seroprevalence of antibodies to hantaviruses and leptospires in selected Italian population groups. LA - Eng MH - Adult MH - Aged MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - Cross-Sectional Studies MH - Hantavirus/*immunology MH - Hemorrhagic Fever with Renal Syndrome/epidemiology/*immunology MH - Human MH - Italy/epidemiology MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*immunology MH - Middle Age MH - Occupations MH - Prevalence MH - Prospective Studies MH - Seroepidemiologic Methods MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 920604 DP - 1992 Jan IS - 0392-2990 TA - Eur J Epidemiol PG - 98-102 SB - M CY - ITALY IP - 1 VI - 8 JC - ERE AA - Author EM - 9208 AB - A study of hantaviral and leptospiral antibodies in selected population groups was performed. Among high risk subjects in the Rome area, Hantaan antibody was found in mammalogists (10%) and dialysis patients (6%), while none of the trappers, oarsmen, river policemen and firemen studied tested positive for antibodies to hantaviruses. In occupationally-exposed subjects (farmers, rangers, lumbermen, hunters) from rural and densely forested areas of northern Italian regions, the prevalence of Hantaan antibody ranged from 3.3% to 8.8%. In the positive cases the comparative antibody titration using different hantaviruses showed a predominance of Hantaan virus (titer 1:128) compared to Puumala virus (titer 1:32); no reactivity was observed with Seoul or Prospect Hill viruses. In Rome, leptospiral antibodies were found in trappers (21%) and oarsmen (5%) at a titer of 1:50 or more, with a predominance for the L. icterohaemorrhagiae serotype (85%). In the Alpine areas the leptospiral antibody prevalence was 12% and L. icterohaemorrhagiae and L. bratislava were the predominant serotypes. The presence of hantavirus infections, suspected after the first epidemiological survey conducted in central Italy, is now supported by the new data obtained in northern Italian regions. Furthermore, the recent observation of one case of Hemorrhagic Fever with Renal Syndrome (HFRS) in the Udine area, not far from the Yugoslavian border, strongly confirms the presence of one or more hantaviruses in Italy. AD - Institute of Tropical and Infectious Diseases, University La Sapienza, Policlinico Umberto I, Rome, Italy. PMID- 1349288 CU - 94 SO - Eur J Epidemiol 1992 Jan;8(1):98-102 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [6 protein links] [1 nucleotide link] [205 medline neighbors] UI - 92211328 AU - Baril C AU - Richaud C AU - Fournie E AU - Baranton G AU - Saint Girons I TI - Cloning of dapD, aroD and asd of Leptospira interrogans serovar icterohaemorrhagiae, and nucleotide sequence of the asd gene. LA - Eng MH - Acyltransferases/*genetics MH - Amino Acid Sequence MH - Aspartate-Semialdehyde Dehydrogenase/biosynthesis/*genetics MH - Base Sequence MH - Cloning, Molecular MH - Corynebacterium/genetics MH - Escherichia coli/genetics MH - *Genes, Bacterial MH - Genetic Complementation Test MH - Hydro-Lyases/*genetics MH - Leptospira interrogans/enzymology/*genetics MH - Molecular Sequence Data MH - Open Reading Frames MH - Saccharomyces cerevisiae/genetics MH - Sequence Homology, Nucleic Acid MH - Streptococcus mutans/genetics MH - Support, Non-U.S. Gov't RN - EC 1.2.1.11 (Aspartate-Semialdehyde Dehydrogenase) RN - EC 2.3. (Acyltransferases) RN - EC 2.3.1.- (succinyl-CoA-tetrahydrodipicolinate N-succinyltransferase) RN - EC 4.2.1. (Hydro-Lyases) RN - EC 4.2.1.10 (3-dehydroquinate dehydratase) PT - JOURNAL ARTICLE DA - 920507 DP - 1992 Jan IS - 0022-1287 TA - J Gen Microbiol PG - 47-53 SB - M CY - ENGLAND VI - 138 ( Pt 1) JC - I87 AA - Author EM - 9207 AB - Metabolites such as diaminopimelate and some aromatic derivatives, not synthesized in mammalian cells, are essential for growth of bacteria. As a first step towards the design of a new human live vaccine that uses attenuated strains of Leptospira interrogans, the asd, aroD and dapD genes, encoding aspartate beta-semialdehyde dehydrogenase, 3- dehydroquinase and tetrahydrodipicolinate N-succinyltransferase, respectively, were cloned by complementation of Escherichia coli mutants. The complete nucleotide sequence of the asd gene was determined and found to contain an open reading frame capable of encoding a protein of 349 amino acids with a calculated Mr of 38,007. Comparison of this deduced L. interrogans aspartate beta-semialdehyde dehydrogenase amino acid sequence with those of the same enzyme from Saccharomyces cerevisiae and Corynebacterium glutamicum revealed 46% and 36% identity, respectively. By contrast, the identity between the L. interrogans enzyme and the Streptococcus mutans or E. coli enzymes was less than 31%. Highly conserved sequences within aspartate semialdehyde dehydrogenase from the five organisms were observed at the amino and carboxyl termini, and around the cysteine of the active site. AD - Unite de Bacteriologie Moleculaire et Medicale, Institut Pasteur, Paris, France. PMID- 1348268 CU - 94 GS - dapD GS - aroD GS - asd SI - GENBANK/M77500 SO - J Gen Microbiol 1992 Jan;138 ( Pt 1):47-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 94211979 AU - Regalado Segui JD AU - Lopez Acosta C AU - Saltaren A AU - Atienzar E TI - [The identification of Leptospira strains of different origins] LA - Spa MH - Cuba MH - English Abstract MH - *Environmental Microbiology MH - Human MH - Leptospira/classification/*isolation & purification MH - Leptospira canicola/classification/isolation & purification MH - Leptospira interrogans/classification/isolation & purification MH - Leptospirosis/microbiology MH - Serotyping MH - Soil Microbiology MH - Water Microbiology MH - Weil's Disease/microbiology PT - JOURNAL ARTICLE DA - 940519 DP - 1992 IS - 0375-0760 TA - Rev Cubana Med Trop PG - 33-6 CY - CUBA IP - 1 VI - 44 JC - RPX AA - Author EM - 9407 AB - Leptospirosis is at present an ever-increasing problem in human and animal health. By means of the Korthof medium, 43 Leptospira strains were isolated from samples of human blood, water and soil. For their identification the microagglutination technique was used. The strains corresponded to the species Leptospira biflexa and Leptospira interrogans. AD - Instituto de Medicina Tropical Pedro Kouri. PMID- 1344685 TT - Identificacion de cepas de leptospira de distintas procedencias. EA - A SO - Rev Cubana Med Trop 1992;44(1):33-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 94100892 AU - De-Souza L AU - Koury MC TI - Chemical and biological properties of endotoxin from Leptospira interrogans serovars canicola and icterohaemorrhagiae. LA - Eng MH - Animal MH - Chick Embryo MH - Comparative Study MH - Complement Hemolytic Activity Assay MH - Endotoxins/analysis/*chemistry/immunology/isolation & purification/toxicity MH - Escherichia coli MH - Immunization MH - *Leptospira canicola/classification MH - *Leptospira interrogans/classification MH - Lethal Dose 50 MH - Limulus Test MH - Rabbits MH - Serotyping MH - Shwartzman Phenomenon/chemically induced MH - Support, Non-U.S. Gov't RN - 0 (Endotoxins) PT - JOURNAL ARTICLE DA - 940210 DP - 1992 IS - 0100-879X TA - Braz J Med Biol Res PG - 467-75 SB - M CY - BRAZIL IP - 5 VI - 25 JC - BOF AA - Author EM - 9404 AB - 1. Endotoxin-like activity was extracted with phenol-chloroform- petroleum either (PCP) from Leptospira interrogans serovars icterohaemorrhagiae and canicola. Chemical analysis of leptospiral cells obtained from the PCP extract indicated the following distribution of lipopolysaccharide (LPS), protein and polysaccharide in mg/ml: 3.0, 4.5 and 1.0 for icterohaemorrhagiae and 3.3, 5.6 and 1.5 for canicola. 2. The preparations presented several biological activities: positive Limulus test (1.0 pg/ml) for icterohaemorrhagiae and canicola PCP extract and 0.5 pg/ml for E. coli O111:B4 LPS, lethality for chicken embryos (LD50 45, 25 and 1.0) for icterohaemorrhagiae, canicola and E. coli O111:B4 LPS, pyrogenicity in rabbits with an average increase in rectal temperature of 0.6 degrees C, 0.9 degrees C and 2.2 degrees C for canicola, icterohaemorrhagiae and E. coli O111:B4 LPS, reacted with complement inhibiting the lysis of sheep red blood cells, 62%, 75% and 90% for 2.0 micrograms/ml of icterohaemorrhagiae, canicola PCP extract and E. coli O111:B4 LPS. The PCP extract showed no cytotoxicity on chicken embryo fibroblasts and epithelial cells. 3. These results demonstrate that Leptospira endotoxin activity is similar to E. coli O111:B4 lipopolysaccharide. AD - Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil. PMID- 1342222 SO - Braz J Med Biol Res 1992;25(5):467-75 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 94023343 AU - Stafford K AU - Stafford Y AU - Paton D AU - Gamble P TI - Antibodies to some swine diseases in commercial piggeries in Central Zambia. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - Swine MH - Swine Diseases/*immunology MH - Zambia RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 931101 DP - 1992 IS - 0035-1865 TA - Rev Elev Med Vet Pays Trop PG - 229-30 CY - FRANCE IP - 3-4 VI - 45 JC - RSH AA - Author EM - 9401 AB - Blood samples were taken from 121 sows and gilts on 7 commercial piggeries located around Lusaka (Zambia). The samples tested negative for antibodies to Aujeszky's disease, transmissible gastroenteritis (TGE), swine influenza, hog cholera and brucellosis. Seventy-eight pigs from 5 farms had positive titres to porcine parvovirus. Eighteen sera showed positive titres to Leptospira celledoni. AD - Samiora Machel School of Veterinary Medicine, UNZA, Lusaka, Zambie. PMID- 1339985 SO - Rev Elev Med Vet Pays Trop 1992;45(3-4):229-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 92246474 AU - Steinen AC AU - Schuurman JL AU - Gravekamp C AU - Korver H AU - Terpstra WJ TI - Muskrats as carriers of pathogenic leptospires in The Netherlands. LA - Eng MH - Animal MH - DNA Restriction Enzymes MH - Leptospira/*isolation & purification MH - Leptospira interrogans/*isolation & purification MH - Microtinae/*microbiology MH - Netherlands MH - Seasons MH - Serotyping MH - Support, Non-U.S. Gov't RN - EC 3.1.21 (DNA Restriction Enzymes) PT - JOURNAL ARTICLE DA - 920604 DP - 1992 Jan IS - 0003-6072 TA - Antonie Van Leeuwenhoek PG - 43-50 SB - M CY - NETHERLANDS IP - 1 VI - 61 JC - 6JE AA - Author EM - 9208 AB - Leptospires were isolated from 24 of 327 (7%) muskrats (Ondatra zibethicus) caught in The Netherlands. All isolates were identified as Leptospira interrogans. One isolate was typed as serovar copenhageni in the Icterohaemorrhagiae serogroup, one as serovar lora in the Australis serogroup. Twenty-one isolates showed a close relationship with serovars grippotyphosa, valbuzzi, muelleri and ratnapura from the Grippotyphosa serogroup. One isolate was lost. Sera from 196 muskrats were examined by the microscopic agglutination test. Forty-five (23%) sera reacted positively (titers greater than or equal to 1:160), 42 (21%) of these 45 sera to Grippotyphosa and 3 (2%) to Sejroe serogroup antigens. This is the first report of serological and cultural evidence of leptospira infection in muskrats in The Netherlands. AD - Royal Tropical Institute, N.H. Swellengrebel Laboratory of Tropical Hygiene, Amsterdam, The Netherlands. PMID- 1315497 CU - 93 SO - Antonie Van Leeuwenhoek 1992 Jan;61(1):43-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 93361768 AU - de Carvalho JE AU - Marchiori E dos S AU - Guedes e Silva JB AU - Netto BA AU - Tavares W AU - de Paula AV TI - [Pulmonary compromise in leptospirosis] LA - Por MH - Adult MH - Aged MH - Antibodies, Bacterial/blood MH - English Abstract MH - Female MH - Human MH - *Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/complications/*diagnosis/pathology MH - Lung/pathology/radiography MH - Lung Diseases/*diagnosis/etiology/pathology MH - Male MH - Middle Age MH - Weil's Disease/complications/*diagnosis/pathology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 930923 DP - 1992 Jan-Mar IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 21-30 CY - BRAZIL IP - 1 VI - 25 JC - RET AA - Author EM - 9311 AB - To study the pulmonary complications in leptospirosis case records of 23 such patients admitted at the Hospital Universitario Antonio Pedro, Universidade Federal Fluminense, Niteroi, Brasil, were reviewed. Hemoptysis were seen in 21.7% and sputal blood in 30.4% of patients. Arterial gasometry detected hypoxemia and hypocapnia in most cases. Thoracic radiology showed an alveolar pattern in 60% of the patients, alveolo-interstitial in 20%, interstitial in 6%, and in 14% the lungs were considered to be normal. Necropsy of 13 cases showed edema, congestion and hemorrhage in the lungs in all cases. Hyaline membrane was found in 30% and fibrin thrombi in 46% of these cases, resulting in a diagnosis of adult respiratory distress syndrome and acute disseminated intravascular coagulation (consumption coagulopathy) in leptospirosis. AD - Hospital Universitario Antonio Pedro, Niteroi, RJ. PMID- 1308063 TT - Comprometimento pulmonar na leptospirose. EA - A SO - Rev Soc Bras Med Trop 1992 Jan-Mar;25(1):21-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 93248786 AU - Vachaev BF AU - Iagovkin EA TI - [The immunochemical and biological properties of Leptospira membranes] LA - Rus MH - Animal MH - Antigens, Bacterial/analysis MH - Bacterial Vaccines/immunology MH - Cell Fractionation MH - Cell Membrane/immunology/ultrastructure MH - Comparative Study MH - English Abstract MH - Hamsters MH - Hypersensitivity, Delayed/immunology MH - Immunization MH - Leptospira interrogans/classification/*immunology/isolation & purification/ultrastructure MH - Mesocricetus MH - Mice MH - Microscopy, Electron MH - Rats MH - Serotyping MH - Solubility RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 930601 DP - 1992 IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 46-9 SB - M CY - RUSSIA IP - 11-12 JC - Y9O AA - Author EM - 9308 AB - The immunochemical and biological properties of purified membrane fractions obtained from Leptospira interrogans, serovar copenhageni, strain Rat 2, and Leptospira biflexa, strain Patoc 1, were studied. The presence of genus-specific and group-specific antigens in leptospiral membranes was established by the methods of immunodiffusion analysis, the microagglutination (MA) and lysis tests. In animal experiments cell membrane preparations produced no toxic and allergic effects. Leptospiral membranes obtained from strain Rat 2 ensured the protection of golden hamsters infected with Leptospira virulent culture and induced antibody production in high titers, detected with the use of the MA test, the lysis test and the enzyme immunoassay, in rabbits immunized in two injections. PMID- 1301663 TT - Immunokhimicheskie i biologicheskie svoistva mebran leptospir. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1992;(11-12):46-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 92041671 AU - Herrmann JL AU - Baril C AU - Bellenger E AU - Perolat P AU - Baranton G AU - Saint Girons I TI - Genome conservation in isolates of Leptospira interrogans. LA - Eng MH - Comparative Study MH - DNA, Bacterial/genetics/isolation & purification MH - Evolution MH - *Genome, Bacterial MH - Human MH - Leptospira interrogans/classification/*genetics/isolation & purification MH - Restriction Mapping MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 911226 DP - 1991 Dec IS - 0021-9193 TA - J Bacteriol PG - 7582-8 SB - M CY - UNITED STATES IP - 23 VI - 173 JC - HH3 AA - Author EM - 9202 AB - Reference strains for each of the 23 serogroups of Leptospira interrogans yielded different pulsed-field gel electrophoresis patterns of NotI digestion products. This was also the case for the 14 serovars belonging to serogroup Icterohaemorrhagiae (with one exception). The NotI restriction patterns of 45 clinical leptospiral isolates belonging to serovar icterohaemorrhagiae were analyzed and compared with those of type strains. No differences were observed between isolates from countries of different continents, namely, France, French Guiana, New Caledonia, and Tahiti. The pattern was indistinguishable from that of the reference strain of serovar icterohaemorrhagiae. AD - Unite de Bacteriologie Moleculaire et Medicale, Institut Pasteur, Paris, France. PMID- 1938954 SO - J Bacteriol 1991 Dec;173(23):7582-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 93004901 AU - Joshi DD TI - Organisation of veterinary public health in the south Asia region. LA - Eng MH - Animal MH - Asia, Southeastern MH - Asia, Western MH - Developing Countries MH - Human MH - Korea MH - Mongolia MH - Public Health Administration/*organization & administration MH - Veterinary Medicine/*organization & administration MH - *World Health Organization MH - *Zoonoses PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 921119 DP - 1991 Dec IS - 0253-1933 TA - Rev Sci Tech PG - 1101-29 SB - M CY - FRANCE IP - 4 VI - 10 JC - A9R AA - Author EM - 9301 AB - In the South Asia region vast human populations are exposed daily and with considerable intensity to close contact with vast animal populations and their excreta. There is no veterinary public health unit in the World Health Organisation (WHO) South-East Asia Regional Office (SEARO) in New Delhi (India), the Western Pacific Regional Office (WPRO) in Manila (Philippines) or the Eastern Mediterranean Regional Office (EMRO) in Alexandria (Egypt). However, these offices do support a number of activities on zoonoses and food-borne diseases in WHO member countries of the region. Maintenance of the health of farmers and of their families (often termed "rural health") has assumed increasing importance in most member countries of the region. In most of the countries, there is no actual veterinary public health unit functioning as a national body common to the ministries of health and agriculture. Among the commonest zoonotic diseases prevalent in member countries are rabies, brucellosis, Japanese encephalitis, echinococcosis, tuberculosis, visceral leishmaniasis, taeniasis, salmonellosis, campylobacteriosis and leptospirosis. A national plan is necessary for each country to give priority to controlling these diseases, based on health systems research or primary health care, with intersectoral and regional cooperation through the South Asian Association for Regional Cooperation (SAARC) under Technical Cooperation among Developing Countries (TCDC). There should be a strong unit for veterinary public health in all WHO regional offices to coordinate zoonotic disease surveillance, training and control programmes in countries of the region. AD - National Zoonoses and Food Hygiene Consulting Centre, Tahachal, Kathmandu, Nepal. RF - 44 PMID- 1840854 SO - Rev Sci Tech 1991 Dec;10(4):1101-29 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 92248670 AU - Tang YK TI - [A field study on the post-inoculation reaction and immunological effects in vaccinated population immunized with "Zhejiang type-D" leptospiral vaccine] LA - Chi MH - Adolescence MH - Adult MH - Antibodies, Bacterial/*blood MH - Bacterial Vaccines/administration & dosage/adverse effects/*immunology MH - English Abstract MH - Female MH - Human MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/prevention & control MH - Male MH - Middle Age MH - Weil's Disease/prevention & control RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 920610 DP - 1991 Dec IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 335-8 CY - CHINA IP - 6 VI - 12 JC - CQG AA - Author EM - 9208 AB - A comparative study on the post-inoculation and antibody responses after inoculation with two different dosage (1ml, 2ml) of "zhejiang type-D" leptospiral vaccine was carried out. There was no general reaction in all of the vaccinated people after immunization. The GMT values of antibody against leptospire were 3.08-7.91 times in 1ml dose group and 3.48-9.57 times in 2ml dose group more than pre-vaccination respectively. 3 months after immunization the levels of specific antibody still were high in most vaccinated people, whatever in 1ml dose or 2ml dose of immunization. However the antibody couldn't be detected in part of vaccinated people at that time, but there was no difference between the two different dosages. During the epidemic season, there was no leptospirosis case (0/3260) in the 1ml group, 1 case (1/625) in the 2 ml group while there was 9/3970 in the control group. AD - Sanitary and anti-epidemic Station of Zhejiang Province, Hangzhou. PMID- 1811891 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1991 Dec;12(6):335-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 92109273 AU - Petchclai B AU - Hiranras S AU - Potha U TI - Gold immunoblot analysis of IgM-specific antibody in the diagnosis of human leptospirosis. LA - Eng MH - Antibodies, Bacterial/*blood MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Gold/immunology MH - Human MH - IgM/*blood MH - Immunoblotting/*methods MH - Leptospirosis/*diagnosis/immunology MH - Serodiagnosis/methods RN - 0 (Antibodies, Bacterial) RN - 0 (IgM) RN - 7440-57-5 (Gold) PT - JOURNAL ARTICLE DA - 920210 DP - 1991 Dec IS - 0002-9637 TA - Am J Trop Med Hyg PG - 672-5 SB - A SB - M CY - UNITED STATES IP - 6 VI - 45 JC - 3ZQ AA - Author EM - 9204 AB - An immunoblot for the detection of leptospirosis was developed in our laboratory. Antigen prepared from Leptospira interrogans serovar bataviae was dotted onto nitrocellulose paper and blocked with skim milk. Test and control sera diluted 1:20 were applied to the dot, incubated, and washed. Anti-human IgM colloidal gold conjugate was added and the dots were washed. A positive reaction was shown by the development of a pink dot against a white background. The test was performed on 62 sera that tested positive for leptospirosis by a microagglutination (MA) test, on 40 sera that were positive by an indirect hemagglutination (IHA) test, and on sera from forty healthy blood donors. Four sera from the blood donors showed a faint pink dot, but the remainder showed a colorless reaction. All 62 sera that tested positive by MA were positive by this new test, while 95% of the 20 sera that tested positive by IHA were positive. Tests for IgG antibody were performed on 20 sera positive by MA using protein A-colloidal gold conjugate, and all showed weak reactivity. The results confirmed previous findings that most antibodies present in leptospirosis patients are of the IgM type. The ELISA takes three hours to perform, but the gold immunoblot can be completed in 30 min. In addition, the test blot can be kept as a permanent record, and is a significant improvement over existing tests. AD - Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand. PMID- 1763792 SO - Am J Trop Med Hyg 1991 Dec;45(6):672-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 92098696 AU - Gerritsen MJ AU - Olyhoek T AU - Smits MA AU - Bokhout BA TI - Sample preparation method for polymerase chain reaction-based semiquantitative detection of Leptospira interrogans serovar hardjo subtype hardjobovis in bovine urine. LA - Eng MH - Animal MH - Cattle MH - DNA, Bacterial/analysis MH - Female MH - Leptospira interrogans/genetics/*isolation & purification MH - *Polymerase Chain Reaction/standards MH - Reference Standards MH - Support, Non-U.S. Gov't MH - Urine/*microbiology MH - Weil's Disease/veterinary RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 920203 DP - 1991 Dec IS - 0095-1137 TA - J Clin Microbiol PG - 2805-8 SB - M CY - UNITED STATES IP - 12 VI - 29 JC - HSH AA - Author EM - 9204 AB - An improved method of preparing bovine urine samples was developed for the rapid, specific, and sensitive detection of Leptospira interrogans serovar hardjo (subtype hardjobovis) DNA by the polymerase chain reaction (PCR). A total of 100 leptospire-free cows, 4 experimentally infected cows, and 2 negative control cows were used. PCR results were improved by (i) using 10-ml urine samples instead of 1-ml samples, (ii) adding 10(7) to 10(8) Leptospira biflexa serovar patoc cells as a carrier to each treated sample, (iii) preventing the loss of pelleted leptospires, and (iv) minimizing the presence of PCR-inhibiting factors in the samples. The preparation method enabled us to use the PCR to reproducibly detect as few as 5 to 10 leptospires per ml of urine without the need for dot blot hybridization. In addition, we were able to estimate the number of leptospires shed by experimentally infected cows. AD - Department of Bacteriology, Central Veterinary Institute, Lelystad, The Netherlands. PMID- 1757552 SO - J Clin Microbiol 1991 Dec;29(12):2805-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 92086965 AU - Akkermans JP TI - [Changed health problems in a changing pig-farming concern in The Netherlands until 1980] LA - Dut MH - Animal MH - Bacterial Infections/therapy/veterinary MH - English Abstract MH - Gastroenteritis, Transmissible, of Swine/therapy MH - Pseudorabies/therapy MH - Rhinitis, Atrophic/therapy/veterinary MH - Swine MH - Swine Diseases/*therapy PT - JOURNAL ARTICLE DA - 920123 DP - 1991 Dec 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 1168-74 SB - M CY - NETHERLANDS IP - 23 VI - 116 JC - VRY AA - Author EM - 9203 AB - In 1905 Poels published 'Disease of swine in the Netherlands'. This book dealt predominantly with swine fever, erysipelas, tuberculosis and 'pneumonia'. Between 1920 and 1940 others reported on streptococci, lobular haemmorrhagic pneumonia, bordetellosis, Aujeszky's disease and postweaning diarrhoea. After the second world war, particularly after 1960, the Dutch pig-farming industry developed at a tremendous rate. As a consequence, the health problems changed. Certain diseases became less important: tuberculosis, erysipelas, Leptospira tarrasovi, enteroviruses. Yet other diseases including postweaning diarrhoea, atrophic rhinitis and Aujeszky's disease became problems of increasing importance. At the end of the seventies the knowledge of E. coli toxin types was substantial. On the other hand, information concerning the pathogenesis and pathophysiology was very limited. Bordetella bronchiseptica was still considered to be the most important agent in AR, zootechnical factors being predisposing. However, one was aware of missing links. Aujeszky's disease was obscure until the late fifties. Until 1972 only occasional reports were made. In that year, an epidemic occurred in the Gelderse Vallei. Another epidemic occurred in 1974 in the provinces of Brabant and Limburg. By 1980 proper vaccines were available and Aujeszky's disease was not yet a political problem. AD - Gezondheidsdienst voor Dieren West- en Midden-Nederland, Gouda. PMID- 1750028 TT - Veranderende gezondheidsproblematiek in een veranderende varkenshouderij in Nederland tot 1980. EA - A SO - Tijdschr Diergeneeskd 1991 Dec 1;116(23):1168-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 92193056 AU - Watson AD TI - Leptospira interrogans serovar bratislava infection [letter; comment] LA - Eng MH - Animal MH - Dog Diseases/*microbiology MH - Dogs MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/*veterinary PT - COMMENT PT - LETTER DA - 920423 DP - 1991 Nov 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1239 SB - M CY - UNITED STATES IP - 10 VI - 199 JC - HAV EM - 9206 CM - Comment on: J Am Vet Med Assoc 1991 Aug 1;199(3):351-2 RO - M:LC1 PMID- 1800472 LR - 920720 SO - J Am Vet Med Assoc 1991 Nov 15;199(10):1239 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 92054788 AU - Edelstein H AU - Rowden R TI - Leptospirosis as a result of elk exposure [letter] LA - Eng MH - Adult MH - Animal MH - Case Report MH - Deer MH - Human MH - Leptospirosis/diagnosis/*etiology MH - Male MH - Meat/*adverse effects PT - LETTER DA - 911226 DP - 1991 Nov IS - 0038-4348 TA - South Med J PG - 1415-6 SB - A SB - M SB - X CY - UNITED STATES IP - 11 VI - 84 JC - UVH EM - 9202 PMID- 1948245 SO - South Med J 1991 Nov;84(11):1415-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 93255364 AU - Yasuda PH AU - Sakata EE AU - Shikanai-Yasuda MA AU - Vasconcelos S de A AU - Romero EC AU - da Silva MV AU - Carrasco S TI - [Evaluation of counterimmunoelectrophoresis with antigens of icterohaemorrhagiae and patoc serovars in the serodiagnosis of human leptospirosis] LA - Por MH - Agglutination Tests MH - Antigens, Bacterial/*blood MH - Comparative Study MH - *Counterimmunoelectrophoresis MH - English Abstract MH - False Negative Reactions MH - False Positive Reactions MH - Human MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis MH - Predictive Value of Tests MH - Support, Non-U.S. Gov't MH - Time Factors MH - Weil's Disease/diagnosis RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 930604 DP - 1991 Nov-Dec IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 497-502 CY - BRAZIL IP - 6 VI - 33 JC - S9D AA - Author EM - 9308 AB - Counterimmunoelectrophoresis (CIE) was applied on paired sera from 135 patients with leptospirosis and on 69 sera from a control group. The sera from patients were subdivided in 4 groups according to the results obtained by the Microscopic Agglutination Test (MAT). The first samples sera from 58 patients were non reagent by MAT. Six monthly samples of sera were taken from 7 patients to follow-up and to determine the level of agglutinin and precipitin antibodies present using MAT and CIE. Serovars icterohaemorrhagiae and patoc were used as antigens. Three types of antigens were compared, 1) Triton-X-100 extracted; 2) heat extracted and 3) a pool of them. The CIE using icterohaemorrhagiae derived antigens types agreed with MAT in 92.64, 92.64 and 94.11% of the leptospirosis sera. The patoc antigens types reacted with the control group in 7.24, 86.95 and 84.05% of the samples, and consequently were eliminated from the present study. The icterohaemorrhagiae CIE reaction become positive earlier than MAT negative sera, and reverted to negative earlier in the follow-up samples from the patients. The CIE was sensitive and specific, gave rapid results and was easy to perform. AD - Instituto de Ciencias Biomedicas da USP, Depto. de Microbiologia, Brasil. PMID- 1844981 TT - Avaliacao da contraimunoeletroforese com antigenos dos sorovars icterohaemorrhagiae E patoc no diagnostico sorologico da leptospirose humana. EA - A SO - Rev Inst Med Trop Sao Paulo 1991 Nov-Dec;33(6):497-502 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 92353179 AU - Grau A AU - Pumarola T AU - Llort JL AU - Murria MJ AU - Bofill D AU - Manresa J AU - Pinas I AU - Gine J TI - [Creatine phosphokinase in leptospirosis] LA - Spa MH - Adolescence MH - Adult MH - Creatine Kinase/*blood MH - English Abstract MH - Fever/etiology MH - Headache/etiology MH - Human MH - Leptospirosis/blood/complications/*enzymology MH - Male MH - Muscular Diseases/etiology MH - Pain/etiology MH - Prognosis RN - EC 2.7.3.2 (Creatine Kinase) PT - JOURNAL ARTICLE DA - 920908 DP - 1991 Nov IS - 0213-005X TA - Enferm Infecc Microbiol Clin PG - 554-6 CY - SPAIN IP - 9 VI - 9 JC - A10 AA - Author EM - 9211 AB - Leptospirosis is a widely-distributed infectious disease, that usually presents with fever, headache and myalgia. Organ involvement could have very different severity degree. We evaluate 21 patients with leptospirosis looking for prognostic and diagnostic value of myalgia and/or elevated creatine-phosphokinase serum levels. Myalgia was recorded in nearly all patients (91%). Creatine-phosphokinase levels above normal limits were seen in 37% of cases, either in severe forms of leptospirosis with organ involvement or in mild forms of disease. We conclude that creatine-phosphokinase elevated levels could be of early diagnosis interest but they are not solely seen in the more severe forms of the disease. AD - Servicio de Medicina Interna, Hospital Verge de la Cinta, Tortosa, Tarragona. PMID- 1822708 TT - Creatinfosfocinasa en la leptospirosis. EA - A SO - Enferm Infecc Microbiol Clin 1991 Nov;9(9):554-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 92227487 AU - Ambalov IuM AU - Kuznetsov VP AU - Zhukova KI TI - [Spontaneous rupture of the spleen in a patient with leptospirosis] LA - Rus MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*complications MH - Male MH - Rupture, Spontaneous MH - Splenic Rupture/*etiology PT - JOURNAL ARTICLE DA - 920521 DP - 1991 Nov IS - 0023-2149 TA - Klin Med (Mosk) PG - 91 CY - USSR IP - 11 VI - 69 JC - KW2 EM - 9207 PMID- 1808426 TT - Spontannyi razryv selezenki u bol'nogo leptospirozom. SO - Klin Med (Mosk) 1991 Nov;69(11):91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 92180241 AU - Paz-Soldan SV AU - Dianderas MT AU - Windsor RS TI - Leptospira interrogans serovar canicola: a causal agent of sow abortions in Arequipa, Peru. LA - Eng MH - Abortion, Veterinary/epidemiology/*microbiology MH - Animal MH - Antibodies, Bacterial/blood MH - Disease Outbreaks/*veterinary MH - Female MH - Kidney/microbiology/pathology MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Liver/pathology MH - Peru/epidemiology MH - Placenta/pathology MH - Pregnancy MH - Swine MH - Swine Diseases/epidemiology/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 920408 DP - 1991 Nov IS - 0049-4747 TA - Trop Anim Health Prod PG - 233-40 SB - M CY - SCOTLAND IP - 4 VI - 23 JC - WG2 AA - Author EM - 9206 AB - An outbreak of abortions, stillbirths, mummified piglets and neonatal deaths in a pig herd in Arequipa, Peru is described. A total of 31 of 240 sows aborted between May and September 1988. When sera were examined 12 of 14 had very high titres of antibody to canicola PC125 and canicola Hond Utrecht, but there were also high titres of antibody to other leptospiral serovars. A detailed investigation was made and serovar canicola PC125 was isolated from the urine of four sows which had aborted and the kidney of one slaughter pig. Antibodies to various serovars of Leptospira were demonstrated in 11 of 17 sows which had aborted, two of six sows which had normal litters, nine of 18 boars, four of 39 slaughter pigs and four of 14 workers on the farm. The outbreak was brought under control by treatment and vaccination coupled with a thorough cleaning of the farm and control of the wild animal population. It is suggested that the infection was brought onto the farm by wild animals and that the disease is more common in Arequipa than was previously supposed. AD - Departamento de Zoonosis, Instituto Nacional de Salud, Chorrillos, Lima, Peru. PMID- 1796527 SO - Trop Anim Health Prod 1991 Nov;23(4):233-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 92152513 AU - Miller DA AU - Wilson MA AU - Beran GW TI - Relationships between prevalence of Leptospira interrogans in cattle, and regional, climatic, and seasonal factors. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Cattle MH - Cattle Diseases/*epidemiology MH - Climate MH - Leptospira interrogans/classification/immunology/*isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Prevalence MH - Seasons MH - United States/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 920317 DP - 1991 Nov IS - 0002-9645 TA - Am J Vet Res PG - 1766-8 SB - M CY - UNITED STATES IP - 11 VI - 52 JC - 40C AA - Author EM - 9205 AB - On the basis of serologic test results and isolation of leptospires from mature cattle, distribution and prevalence of Leptospira interrogans serovars and genotypes were compared by state and region of the United States. Relationships between isolation rate and month of sample collection, mean regional temperature, and mean regional precipitation were examined. Isolation rate and seroprevalence were significantly (P less than 0.001) higher for southeastern, south central, and Pacific coastal regions than for other regions of the United States. Isolates of genotypes hardjo-bovis A and kennewicki A and B, and of serovar grippotyphosa appeared to be randomly distributed. Genotype hardjo-bovis B isolates came from a southern area of the country that extends from Georgia to New Mexico. To the authors' knowledge, this is the first recorded isolation of serovar hardjo from Hawaii. Although significant relationship was not documented between isolation rate and month or season of the year, seroprevalence for summer, fall, and winter was significantly (P less than 0.001) higher than that for spring. Regional isolation rate was related more to mean temperature (r = 0.83; P less than 0.05) than to mean precipitation amount (r = 0.34; P greater than 0.50). AD - National Veterinary Services Laboratories, US Department of Agriculture, Ames, IA 50010. PMID- 1785720 SO - Am J Vet Res 1991 Nov;52(11):1766-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 92152512 AU - Miller DA AU - Wilson MA AU - Beran GW TI - Survey to estimate prevalence of Leptospira interrogans infection in mature cattle in the United States. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/blood MH - Cattle MH - Cattle Diseases/*epidemiology MH - Comparative Study MH - Female MH - Fluorescent Antibody Technique MH - Kidney/parasitology MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Prevalence MH - Puerto Rico/epidemiology MH - United States/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 920317 DP - 1991 Nov IS - 0002-9645 TA - Am J Vet Res PG - 1761-5 SB - M CY - UNITED STATES IP - 11 VI - 52 JC - 40C AA - Author EM - 9205 AB - A total of 5,142 kidney tissue samples and 5,111 serum samples from mature cattle in 49 states and Puerto Rico were collected at slaughter. Age of cattle ranged from 1 to 16 years (mean, 6.6 years). Leptospires were isolated from 88 (1.7%) kidney tissues, and 2,493 (49%) sera contained antibodies against 1 or more of 12 Leptospira interrogans serovars. Leptospires were observed by immunofluorescence in 41 (0.8%) kidney tissues. Using agglutinin-absorption tests, 73 (83%) isolates were identified as serovar hardjo, 11 (12.5%) as serovar pomona, and 4 (4.5%) as serovar grippotyphosa. By use of restriction endonuclease analysis studies of chromosomal DNA, all isolates differed from reference serovars but were identical to strains previously isolated from cattle or swine in the United States. Of the serovar hardjo isolates, 85% were identical to restriction endonuclease analysis type (genotype) hardjo-bovis A and 11 (15%) were identical to genotype hardjo-bovis B. Serovar pomona isolates were identical to genotypes kennewicki A (64%) or kennewicki B (36%), and serovar grippotyphosa isolates were identical to the RM 52 strain. Isolation rates were significantly (P less than 0.001) higher for beef cattle than for dairy cattle and were higher (P less than 0.001) for bulls than for cows. Combined culture and immunofluorescence results indicated that 2% of mature cattle were renal carriers of leptospires. AD - National Veterinary Services Laboratories, USDA, Ames, IA 50010. PMID- 1785719 SO - Am J Vet Res 1991 Nov;52(11):1761-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 92132369 AU - Estavoyer JM AU - Racadot E AU - Couetdic G AU - Leroy J AU - Grosperrin L TI - Tumor necrosis factor in patients with leptospirosis [letter; comment] LA - Eng MH - Adult MH - Female MH - Human MH - Male MH - Tumor Necrosis Factor/*analysis MH - Weil's Disease/*blood RN - 0 (Tumor Necrosis Factor) PT - COMMENT PT - LETTER DA - 920305 DP - 1991 Nov-Dec IS - 0162-0886 TA - Rev Infect Dis PG - 1245-6 SB - M CY - UNITED STATES IP - 6 VI - 13 JC - SXN EM - 9205 CM - Comment on: Rev Infect Dis 1991 Mar-Apr;13(2):207-10 RO - M:LC1 PMID- 1775860 LR - 920609 CU - 92 SO - Rev Infect Dis 1991 Nov-Dec;13(6):1245-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 92131703 AU - Abramowsky C AU - Beyer-Patterson P AU - Cortinas E TI - Nonsyphilitic spirochetosis in second-trimester fetuses. LA - Eng MH - Adolescence MH - Adult MH - Borrelia/isolation & purification MH - Female MH - Fetal Diseases/metabolism/*microbiology/pathology MH - Human MH - Immunoenzyme Techniques MH - Leptospira/isolation & purification MH - Pregnancy MH - Pregnancy Trimester, Second MH - Spirochaetales Infections/metabolism/*microbiology/pathology MH - Treponema pallidum/isolation & purification PT - JOURNAL ARTICLE DA - 920305 DP - 1991 Nov-Dec IS - 0277-0938 TA - Pediatr Pathol PG - 827-38 SB - M CY - UNITED STATES IP - 6 VI - 11 JC - PEE AA - Author EM - 9205 AB - Four female fetuses (17-23 weeks) spontaneously aborted by young women (15-19 years old) showed spirochetal microorganisms predominantly in the intestinal lumen and mucosa and to a much lesser extent in other organs. Fetal tissues showed a brisk lymphocytic-plasmacytic response in intestinal mucosa, lungs, and meninges in some cases. In all instances the placenta had chorioamnionitis and severe chronic villitis, with villous vasculitis in some. One fetus had a concomitant cytomegalovirus infection. The observed lesions were reminiscent of Treponema pallidum infections; however, the spirochetes were morphologically different by light and ultrastructural microscopy from T. pallidum and did not react with a silver-enhanced, gold-labeled anti- T. pallidum antibody. In addition, serologic tests for syphilis of the women before or after the abortions were nonreactive. On the basis of clinical pathologic considerations as well as the absence of immunostaining, it is possible also to rule out infections caused by Lyme and relapsing fever Borrelia, Leptospira, and Campylobacter. The spirochetes' prominent tropism for the intestinal tract raises the possibility of a congenital infection with gastrointestinal spirochetal species described in recent years. The placental findings suggest an ascending transamniotic infection, with initial colonization of the intestinal tract and systemic dissemination of the organisms in the fetus and placental villi. AD - Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235. PMID- 1775399 SO - Pediatr Pathol 1991 Nov-Dec;11(6):827-38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 92058914 AU - Edwards CN AU - Evarard CO TI - Hyperamylasemia and pancreatitis in leptospirosis. LA - Eng MH - Adult MH - Aged MH - Aged, 80 and over MH - Amylases/*blood MH - Case Report MH - Diagnosis, Differential MH - Female MH - Human MH - Leptospirosis/*complications/enzymology MH - Male MH - Pancreatitis/*diagnosis/enzymology/*etiology MH - Support, Non-U.S. Gov't RN - EC 3.2.1.- (Amylases) PT - JOURNAL ARTICLE DA - 911217 DP - 1991 Nov IS - 0002-9270 TA - Am J Gastroenterol PG - 1665-8 SB - M SB - X CY - UNITED STATES IP - 11 VI - 86 JC - 3HE AA - Author EM - 9202 AB - Hyperamylasemia has been documented in up to 65% of our patients with leptospirosis and jaundice. However, pancreatitis is an uncommon complication of leptospirosis. Three patients with leptospirosis and pancreatitis are described and compared with two leptospirosis patients who had hyperamylasemia but in whom the diagnosis of pancreatitis could not be substantiated. The cause of the hyperamylasemia in the latter patients was nonpancreatic. The elevation of the amylase in these latter two patients could not be explained by renal insufficiency, because the level of the amylase was greater than three to four times the normal value, the upper limit to which amylase rises in renal failure. Thus, hyperamylasemia in patients with leptospirosis can be from pancreatic and nonpancreatic sources. Leptospirosis should be considered in the differential diagnosis of hyperamylasemia and pancreatitis. AD - Queen Elizabeth Hospital, Bridgetown, Barbados. PMID- 1719805 CU - 95 SO - Am J Gastroenterol 1991 Nov;86(11):1665-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 92042672 AU - Kron MA AU - Gupta A AU - Mackenzie CD TI - Identification of related DNA sequences in Borrelia burgdorferi and two strains of Leptospira interrogans by using polymerase chain reaction. LA - Eng MH - Animal MH - Base Sequence MH - Borrelia burgdorferi/*genetics MH - Comparative Study MH - DNA Probes MH - DNA, Bacterial/*genetics MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - Sequence Homology, Nucleic Acid MH - Species Specificity MH - Support, Non-U.S. Gov't MH - Ticks/microbiology RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 911223 DP - 1991 Oct IS - 0095-1137 TA - J Clin Microbiol PG - 2338-40 SB - M CY - UNITED STATES IP - 10 VI - 29 JC - HSH AA - Author EM - 9202 AB - The suitability of a polymerase chain reaction assay for Borrelia burgdorferi in epidemiological studies of infected tick populations was evaluated by using 28 strains of Leptospira interrogans and lysates of fixed adult Ixodes tick tissues. Two false positives representing leptospires were differentiated from B. burgdorferi by using an oligonucleotide probe. AD - Department of Pathology, College of Human Medicine, Michigan State University, East Lansing 48824. PMID- 1939594 CU - 92 SO - J Clin Microbiol 1991 Oct;29(10):2338-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 92026654 AU - Katz AR AU - Manea SJ AU - Sasaki DM TI - Leptospirosis on Kauai: investigation of a common source waterborne outbreak. LA - Eng MH - Abortion, Veterinary MH - Adolescence MH - Adult MH - Animal MH - Cattle MH - Child MH - *Disease Outbreaks MH - Female MH - Fresh Water MH - Hawaii MH - Human MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/*epidemiology/etiology MH - Male MH - Pregnancy MH - Rodentia MH - Swimming MH - Water Microbiology PT - JOURNAL ARTICLE DA - 911108 DP - 1991 Oct IS - 0090-0036 TA - Am J Public Health PG - 1310-2 SB - A SB - M CY - UNITED STATES IP - 10 VI - 81 JC - 3XW AA - Author EM - 9201 AB - During the summer of 1987, a common source waterborne outbreak of leptospirosis occurred on the island of Kauai in the state of Hawaii. Eight leptospirosis cases were identified using the microscopic agglutination test. Methodologic weaknesses in this technique were responsible for the initial missed diagnosis on six of the eight cases. All cases had repeated exposure to the Waimea River. A wide array of animal reservoirs and optimal water conditions may have been factors in this outbreak. AD - University of Hawaii, School of Public Health, Honolulu 96822. PMID- 1928530 SO - Am J Public Health 1991 Oct;81(10):1310-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [20 nucleotide links] [154 medline neighbors] UI - 92011369 AU - Paster BJ AU - Dewhirst FE AU - Weisburg WG AU - Tordoff LA AU - Fraser GJ AU - Hespell RB AU - Stanton TB AU - Zablen L AU - Mandelco L AU - Woese CR TI - Phylogenetic analysis of the spirochetes. LA - Eng MH - Animal MH - Base Sequence MH - Molecular Sequence Data MH - *Phylogeny MH - RNA, Ribosomal, 16S/chemistry/*genetics MH - Shrews MH - Species Specificity MH - Spirochaeta/*genetics MH - Support, U.S. Gov't, Non-P.H.S. MH - Support, U.S. Gov't, P.H.S. RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE ID - DE-04881/DE/NIDR ID - DE-08303/DE/NIDR DA - 911104 DP - 1991 Oct IS - 0021-9193 TA - J Bacteriol PG - 6101-9 SB - M CY - UNITED STATES IP - 19 VI - 173 JC - HH3 AA - Author EM - 9201 AB - The 16S rRNA sequences were determined for species of Spirochaeta, Treponema, Borrelia, Leptospira, Leptonema, and Serpula, using a modified Sanger method of direct RNA sequencing. Analysis of aligned 16S rRNA sequences indicated that the spirochetes form a coherent taxon composed of six major clusters or groups. The first group, termed the treponemes, was divided into two subgroups. The first treponeme subgroup consisted of Treponema pallidum, Treponema phagedenis, Treponema denticola, a thermophilic spirochete strain, and two species of Spirochaeta, Spirochaeta zuelzerae and Spirochaeta stenostrepta, with an average interspecies similarity of 89.9%. The second treponeme subgroup contained Treponema bryantii, Treponema pectinovorum, Treponema saccharophilum, Treponema succinifaciens, and rumen strain CA, with an average interspecies similarity of 86.2%. The average interspecies similarity between the two treponeme subgroups was 84.2%. The division of the treponemes into two subgroups was verified by single-base signature analysis. The second spirochete group contained Spirochaeta aurantia, Spirochaeta halophila, Spirochaeta bajacaliforniensis, Spirochaeta litoralis, and Spirochaeta isovalerica, with an average similarity of 87.4%. The Spirochaeta group was related to the treponeme group, with an average similarity of 81.9%. The third spirochete group contained borrelias, including Borrelia burgdorferi, Borrelia anserina, Borrelia hermsii, and a rabbit tick strain. The borrelias formed a tight phylogenetic cluster, with average similarity of 97%. (ABSTRACT TRUNCATED AT 250 WORDS) AD - Forsyth Dental Center, Boston, Massachusetts 02115. PMID- 1917844 SI - GENBANK/M57740 SI - GENBANK/M71239 SI - GENBANK/M34262 SI - GENBANK/M34260 SI - GENBANK/M34263 SI - GENBANK/M34264 SI - GENBANK/M34265 SI - GENBANK/M57737 SI - GENBANK/M59294 SI - GENBANK/M71236 SI - GENBANK/M71237 SI - GENBANK/M34266 SI - GENBANK/M57739 SI - GENBANK/M71238 SI - GENBANK/M57738 SI - GENBANK/M57741 SI - GENBANK/M57744 SI - GENBANK/M72398 SI - GENBANK/M59293 SI - GENBANK/M72397 SI - GENBANK/M72396 SI - GENBANK/M34261 SI - GENBANK/M71241 SI - GENBANK/X17547 SI - GENBANK/M34118 SI - GENBANK/M59179 SI - GENBANK/M71240 SI - + SO - J Bacteriol 1991 Oct;173(19):6101-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 92340135 AU - Venkataraman KS AU - Nedunchelliyan S TI - Canicola fever in man. LA - Eng MH - Animal MH - Disease Vectors MH - Dog Diseases/*epidemiology/microbiology MH - Dogs MH - Human MH - India/epidemiology MH - *Leptospira canicola MH - Leptospirosis/*epidemiology/microbiology/*veterinary MH - *Zoonoses PT - JOURNAL ARTICLE DA - 920827 DP - 1991 Oct-Dec IS - 0019-557X TA - Indian J Public Health PG - 121-2 CY - INDIA IP - 4 VI - 35 JC - GLN EM - 9210 AD - Dept. of Prev. Medicine, Veterinary College and Research Institute, Tamil Nadu. PMID- 1821886 SO - Indian J Public Health 1991 Oct-Dec;35(4):121-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 92197181 AU - Pupkevich-Diamant IaS TI - [K. N. Tokarevich and the study of leptospiral infection in the USSR (on the 90th anniversary of his birth and the achievements of his creative work)] LA - Rus MH - History of Medicine, 20th Cent. MH - Human MH - Leptospirosis/*history MH - Research/history MH - USSR MH - Weil's Disease/history PT - BIBLIOGRAPHY PT - HISTORICAL ARTICLE PT - BIOGRAPHY PT - JOURNAL ARTICLE DA - 920422 DP - 1991 Oct IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 81-5 SB - M CY - USSR IP - 10 JC - Y9O EM - 9206 PMID- 1801499 CU - 96 PS - Tokarevich KN TT - K. N. Tokarevich i izuchenie leptospiroznoi infektsii v SSSR (k 90- letiiu so dnia rozhdeniia i itogam tvorcheskogo puti). SO - Zh Mikrobiol Epidemiol Immunobiol 1991 Oct;(10):81-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 92163856 AU - Van Til LD AU - Dohoo IR TI - A serological survey of leptospirosis in Prince Edward Island swine herds and its association with infertility. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Follow-Up Studies MH - Infertility/etiology/*veterinary MH - Least-Squares Analysis MH - Leptospira interrogans/immunology MH - Leptospirosis/complications/epidemiology/*veterinary MH - Microcomputers MH - Prevalence MH - Prince Edward Island/epidemiology MH - Software MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*epidemiology/etiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 920402 DP - 1991 Oct IS - 0830-9000 TA - Can J Vet Res PG - 352-5 SB - M CY - CANADA IP - 4 VI - 55 JC - CKL AA - Author EM - 9206 AB - A serological survey was undertaken to determine the prevalence of leptospirosis, and to investigate associations between leptospiral antibody titers, and herd measures of reproduction. Production records and leptospirosis serology were analyzed for 25 slaughter hogs from each of eleven randomly sampled farrow-finish operations on Prince Edward Island. The effect of selected leptospiral serovars on nonproductive sow days per parity (NPSD/P) and the proportion of pigs born dead was evaluated. The four most common serovars to which antibodies were detected were Leptospira icterohaemorrhagiae, L. bratislava, L. autumnalis and L. pomona, with respective prevalences of 57.1%, 35.1%, 3.4% and 1.5% of PEI slaughter hogs. None of these serovars was associated with increased frequency of stillbirths (p greater than 0.05). However, farms with a higher prevalence of L. bratislava antibody titers tended to have more infertility, as measured by NPSD/P (r = 0.738, p = 0.036 with Bonferroni adjustment). Also, farms with L. pomona antibody titers had higher NPSD/P than farms without L. pomona antibody titers (p = 0.0008 with Bonferroni adjustment). There was no association between NPSD/P and antibodies to either L. autumnalis or L. icterohaemorrhagiae (p greater than 0.05). AD - Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown. PMID- 1790491 SO - Can J Vet Res 1991 Oct;55(4):352-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 92117372 AU - Behymer DE AU - Riemann HP AU - Utterback W AU - D-Elmi C AU - Franti CE TI - Mass screening of cattle sera against 14 infectious disease agents, using an ELISA system for monitoring health in livestock. LA - Eng MH - Age Factors MH - Animal MH - Antibodies/*blood MH - Antigens/diagnostic use MH - California/epidemiology MH - Cattle MH - Cattle Diseases/epidemiology/*prevention & control MH - *Enzyme-Linked Immunosorbent Assay MH - Mass Screening/*veterinary MH - Prevalence MH - Seasons MH - Software MH - Support, Non-U.S. Gov't RN - 0 (Antibodies) RN - 0 (Antigens) PT - JOURNAL ARTICLE DA - 920214 DP - 1991 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1699-705 SB - M CY - UNITED STATES IP - 10 VI - 52 JC - 40C AA - Author EM - 9204 AB - Mass screening ELISA methods were developed for testing cattle serum for antibodies against 14 common livestock diseases simultaneously. The absorbance values were transformed to a %ELISA (spectrophotometric antibody end point) by a computer interfaced with a microplate reader. A histogram indicating a cutoff point and a report for the veterinarian also was generated. The computer program produced a print-out of the antibody profile for each animal tested, the antibody concentration against each disease, and a histogram (antibody profile) showing the prevalence of each disease in the herd. Serum samples were obtained from 1,953 cattle, including 880 dairy cattle from 10 herds and 1,073 beef cattle from 20 herds. These samples were obtained from June 1988 through June 1989. The highest antibody prevalence was against bluetongue virus. Of the 1,953 cattle tested, 1,223 (63%) were seropositive for bluetongue virus, including 502 (57%) of the dairy cattle and 721 (67%) beef cattle. Other antibody prevalences, in descending order, were: rotavirus (44%), Pasteurella spp (25%), Leptospira spp and Haemophilus spp (22%), Mycoplasma spp (18%), parainfluenza virus (17%), Campylobacter spp (16%), Anaplasma marginale (15%), bovine leukosis virus (13%), Brucella spp (8%), Mycobacterium paratuberculosis (8%), bovine viral diarrhea virus (3%), and infectious bovine rhinotracheitis virus (3%). Major differences in antibody prevalence between dairy and beef cattle were that only 4% of the dairy cattle were seropositive for A marginale, compared with 25% of the beef cattle, and conversely, 29% of the dairy cattle were seropositive for bovine leukosis virus, compared with 1% of the beef cattle.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Epidemiology and Preventive Medicine, School of Veterinary Medicine, University of California, Davis 95616. PMID- 1767993 SO - Am J Vet Res 1991 Oct;52(10):1699-705 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 92117361 AU - Bolin CA AU - Cassells JA AU - Zuerner RL AU - Trueba G TI - Effect of vaccination with a monovalent Leptospira interrogans serovar hardjo type hardjo-bovis vaccine on type hardjo-bovis infection of cattle. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Fallopian Tubes/microbiology MH - Female MH - Fluorescent Antibody Technique MH - Immunoenzyme Techniques MH - Kidney/microbiology MH - Leptospira interrogans/*immunology/isolation & purification MH - Leptospirosis/prevention & control/*veterinary MH - Male MH - Uterus/microbiology MH - Vaccination/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 920214 DP - 1991 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1639-43 SB - M CY - UNITED STATES IP - 10 VI - 52 JC - 40C AA - Author EM - 9204 AB - Effectiveness of 2 concentrations of a monovalent vaccine containing Leptospira interrogans serovar hardjo type hardjo-bovis was evaluated for protection of heifers from infection with type hardjo-bovis. Nine heifers were given 2 doses of low-dose vaccine (8.32 x 10(8) cells/dose); 9 heifers were given 2 doses of high-dose vaccine (8.32 x 10(9) cells/dose); and 1 steer and 1 heifer were maintained as nonvaccinated controls. Groups of vaccinated cattle were challenge- exposed with serovar hardjo type hardjo-bovis at 7 (n = 6), 11 (n = 6), or 15 (n = 6) weeks after completion of vaccination. All cattle were challenge-exposed by conjunctival instillation of 1 x 10(5) hardjo- bovis cells on 3 consecutive days. Both control and all vaccinated cattle became infected and shed serovar hardjo type hardjo-bovis in their urine. Leptospires were detected in 15 of 16 (94%) urine samples from control cattle and in 124 of 143 (87%) samples from vaccinated cattle. Leptospires were detected in kidneys of 17 of 18 vaccinated cattle and 2 of 2 control cattle and in the uterus or oviducts of 13 of 18 vaccinates and the 1 control heifer. AD - Leptospirosis Mycobacteriosis Research Unit, National Animal Disease Center, USDA, Ames, IA 50010. PMID- 1767985 SO - Am J Vet Res 1991 Oct;52(10):1639-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 92103093 AU - Whipple DL AU - Callihan DR AU - Jarnagin JL TI - Cultivation of Mycobacterium paratuberculosis from bovine fecal specimens and a suggested standardized procedure. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Feces/*microbiology MH - Mycobacterium paratuberculosis/*isolation & purification MH - Paratuberculosis/*diagnosis PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 920212 DP - 1991 Oct IS - 1040-6387 TA - J Vet Diagn Invest PG - 368-73 SB - M CY - UNITED STATES IP - 4 VI - 3 JC - A2D EM - 9204 AD - Leptospirosis/Mycobacteriosis Research Unit, National Animal Disease Center, USDA, Ames, IA 50010. RF - 46 PMID- 1760476 SO - J Vet Diagn Invest 1991 Oct;3(4):368-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 92020115 AU - Zuerner RL TI - Physical map of chromosomal and plasmid DNA comprising the genome of Leptospira interrogans. LA - Eng MH - *Chromosome Mapping MH - Cloning, Molecular MH - DNA Restriction Enzymes/metabolism MH - DNA, Bacterial/*genetics MH - Genes, Bacterial MH - Leptospira interrogans/*genetics MH - Nucleic Acid Hybridization MH - *Plasmids MH - Restriction Mapping RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 911104 DP - 1991 Sep 25 IS - 0305-1048 TA - Nucleic Acids Res PG - 4857-60 SB - M SB - X CY - ENGLAND IP - 18 VI - 19 JC - O8L AA - Author EM - 9201 AB - The size and physical structure of the Leptospira interrogans genome was characterized using contour-clamped homogenous electric field (CHEF) gel electrophoresis. The L. interrogans genome is approximately 4750 kb in size and is composed of two molecular species of DNA: a 4400 kb chromosome; and a 350 kb plasmid, pLIN1. A physical map of the chromosome was constructed with the restriction enzymes NotI and SfiI. A physical map of pLIN1 was constructed with ApaI, NotI, Sse83871, SgrAI, and SmaI. Both the L. interrogans chromosome and pLIN1 are circular. AD - Leptospirosis and Mycobacteriosis Research Unit, US Department of Agriculture, Ames, IA 50010. PMID- 1656379 CU - 93 SO - Nucleic Acids Res 1991 Sep 25;19(18):4857-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 92061843 AU - King S TI - The prevalence of leptospirosis in cattle herds of the Western Division of New South Wales--a serological survey. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/blood/*epidemiology MH - *Leptospira interrogans/classification/immunology MH - Leptospirosis/blood/epidemiology/*veterinary MH - New South Wales/epidemiology MH - Prevalence MH - Rain MH - Seasons MH - Serotyping/veterinary MH - Species Specificity PT - JOURNAL ARTICLE DA - 911226 DP - 1991 Sep IS - 0005-0423 TA - Aust Vet J PG - 307-8 SB - M CY - AUSTRALIA IP - 9 VI - 68 JC - 9IE EM - 9202 AD - NSW Agriculture & Fisheries, Newcastle. PMID- 1953566 SO - Aust Vet J 1991 Sep;68(9):307-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 92061841 AU - Palit A AU - Middleton H AU - Sheers J AU - Basilone C TI - The influence of maternal antibody and age of calves on effective vaccination against Leptospira interrogans serovar hardjo. LA - Eng MH - Age Factors MH - Agglutination Tests/veterinary MH - Animal MH - Bacterial Vaccines/*immunology MH - Cattle MH - Cattle Diseases/*immunology MH - Female MH - Immunity, Maternally-Acquired/*immunology MH - Leptospira interrogans/*immunology/pathogenicity MH - Leptospirosis/immunology/*veterinary MH - Pregnancy MH - Vaccination/*veterinary MH - Virulence RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 911226 DP - 1991 Sep IS - 0005-0423 TA - Aust Vet J PG - 299-303 SB - M CY - AUSTRALIA IP - 9 VI - 68 JC - 9IE AA - Author EM - 9202 AB - Twelve seronegative cows were vaccinated with an experimental bivalent Leptospira interrogans serovars hardjo and pomona vaccine late in their first pregnancy. Calves born of these dams were divided into 4 equal groups that received this vaccine at 4, 6, 10 and 18 weeks of age, respectively. Before vaccination the group geometric mean titres of maternally-derived circulating antibodies ranged from 2 to 25 for the microscopic agglutination (MA) test and 3 to 35 for enzyme-linked immunosorbent assay (ELISA) using a serovar hardjo outer envelope antigen. Post-vaccination peak titres were 645 to 1612 for MA and 562 to 1037 for ELISA, respectively. Calves vaccinated at the youngest age, had the highest pre-vaccination circulating maternal antibody titres, but showed the smallest rise in post-vaccination antibody titres. Circulating maternal antibody was detected in calves up to 13 weeks of age. All immunised calves were protected against a virulent challenge with serovar hardjo type Hardjobovis, regardless of their age or maternally-derived antibody titres. These findings indicate that calves as young as 4 weeks old, vaccinated in the presence of maternally- derived antibody, can be fully protected against homologous virulent challenge. AD - Commonwealth Serum Laboratories, Parkville, Victoria. PMID- 1953564 SO - Aust Vet J 1991 Sep;68(9):299-303 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 92061838 AU - Robertson ID AU - Hampson DJ AU - Mhoma JR TI - The adoption of management and husbandry procedures by Western Australian pig farmers. LA - Eng MH - Animal MH - Animal Husbandry/*methods/statistics & numerical data MH - Antibiotics/administration & dosage/therapeutic use MH - Female MH - Questionnaires MH - Rodent Control/methods MH - Support, Non-U.S. Gov't MH - *Swine MH - Swine Diseases/prevention & control MH - Vaccination/veterinary MH - Veterinary Medicine MH - Western Australia RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 911226 DP - 1991 Sep IS - 0005-0423 TA - Aust Vet J PG - 291-3 SB - M CY - AUSTRALIA IP - 9 VI - 68 JC - 9IE AA - Author EM - 9202 AB - A postal survey was conducted to determine the management and husbandry procedures adopted by a sample of 101 Western Australian pig farmers. Seventy seven replies were received and analysed. Over 80% of farmers vaccinated breeding stock against leptospirosis and erysipelas, 35% vaccinated against parvo virus and 15% vaccinated against Escherichia coli. Most farmers used antibiotics: 72% incorporated them into their pig diets and 60% used parenteral antibiotics. Fifty three per cent of farmers reported that they regularly used a veterinarian. Over 59% of piggeries had another piggery located within 10 km, thus increasing the possibility for disease transmission between herds. It is concluded that there is potential for veterinarians to offer advice to pig farmers, particularly on disease control measures and adoption of technological advances. AD - School of Veterinary Studies, Murdoch University, Western Australia. PMID- 1953561 SO - Aust Vet J 1991 Sep;68(9):291-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 91362504 AU - Silpapojakul K AU - Ukkachoke C AU - Krisanapan S AU - Silpapojakul K TI - Rickettsial meningitis and encephalitis. LA - Eng MH - Adolescence MH - Adult MH - Case Report MH - Chloramphenicol/therapeutic use MH - Diagnosis, Differential MH - Doxycycline/therapeutic use MH - Encephalitis/*microbiology MH - Female MH - Human MH - Male MH - Meningitis/*microbiology MH - Middle Age MH - Scrub Typhus/diagnosis/drug therapy/*epidemiology MH - Thailand/epidemiology MH - Typhus, Endemic Flea-Borne/diagnosis/drug therapy/*epidemiology RN - 56-75-7 (Chloramphenicol) RN - 564-25-0 (Doxycycline) PT - JOURNAL ARTICLE DA - 911004 DP - 1991 Sep IS - 0003-9926 TA - Arch Intern Med PG - 1753-7 SB - A SB - M SB - X CY - UNITED STATES IP - 9 VI - 151 JC - 7FS AA - Author EM - 9112 AB - Nine of 72 patients with scrub typhus and three of 137 with murine typhus presented with meningitis and/or encephalitis syndromes. Focal neurologic signs were rare, and cerebrospinal fluid profiles were similar to those of leptospirosis and viral and tuberculous meningitis. One patient had papilledema, and another had cerebellitis. Other major organ involvement (renal, liver, or lungs) occurred in five patients. One patient died and four spontaneously recovered, while the conditions of the rest responded well to either chloramphenicol or doxycycline. Scrub and murine typhus should be included in the differential diagnoses of aseptic meningitis and encephalitis in patients exposed to endemic areas, especially when accompanied by renal insufficiency and/or jaundice. They are treatable forms of virallike meningoencephalitis. AD - Department of Medicine, Faculty of Medicine, Prince of Songkla University, Thailand. PMID- 1888241 SO - Arch Intern Med 1991 Sep;151(9):1753-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 93255349 AU - Koury MC AU - Rangel HA TI - Isolation and characterization of partially purified leptospiral antigens. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial/*isolation & purification MH - Chromatography, Gel MH - Complement Fixation Tests MH - Heat MH - Immunodiffusion MH - Leptospira canicola/*immunology MH - Rabbits MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 930604 DP - 1991 Sep-Oct IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 391-6 CY - BRAZIL IP - 5 VI - 33 JC - S9D AA - Author EM - 9308 AB - The methanol extract of Leptospira interrogans serovar canicola was purified by precipitation with acetone or acetone and chloroform. The antigenicity of the antigen was not altered by heating or treatment with pepsin and pronase. However the antigenicity was lost when the antigen was treated with periodic acid. Chemical analysis revealed the presence of 40% carbohydrate (22% methylpentose, 28% hexoses), 4% protein, 20% lipid and 2.7% phosphate. The complement fixation test with sera from patients with leptospirosis agreed with the microscopic agglutination reaction. AD - Department of Microbiology, ICB/UFMg, Belo Horizonte, Brazil. PMID- 1844967 SO - Rev Inst Med Trop Sao Paulo 1991 Sep-Oct;33(5):391-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 92261439 AU - Ramanathan M AU - Teng TL TI - Nonmenstrual toxic shock syndrome--a case report. LA - Eng MH - Adult MH - Case Report MH - Cloxacillin/therapeutic use MH - Diagnosis, Differential MH - Female MH - Fluid Therapy MH - Human MH - Leptospirosis/diagnosis MH - *Shock, Septic/diagnosis/therapy RN - 61-72-3 (Cloxacillin) PT - JOURNAL ARTICLE DA - 920612 DP - 1991 Sep IS - 0300-5283 TA - Med J Malaya PG - 283-6 CY - MALAYSIA IP - 3 VI - 46 JC - M2M AA - Author EM - 9208 AB - We present a young lady who satisfied the criteria for the diagnosis of toxic-shock syndrome (TSS). The differential diagnoses of TSS in the local setting are outlined. The pertinent clinical features of TSS and its increasing association with nonmenstruating females are highlighted. AD - Department of Medicine, General Hospital, Melaka. PMID- 1839926 CU - 92 SO - Med J Malaya 1991 Sep;46(3):283-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 92159535 AU - West HJ TI - Evaluation of total serum bile acid concentrations for the diagnosis of hepatobiliary disease in cattle. LA - Eng MH - Animal MH - Bile Acids and Salts/*blood MH - Biliary Tract Diseases/diagnosis/*veterinary MH - Blood Preservation MH - Cattle MH - Cattle Diseases/*diagnosis MH - Comparative Study MH - Evaluation Studies MH - Liver/enzymology MH - Liver Diseases/diagnosis/*veterinary MH - Predictive Value of Tests MH - Sulfobromophthalein/diagnostic use/pharmacokinetics RN - 0 (Bile Acids and Salts) RN - 71-67-0 (Sulfobromophthalein) PT - JOURNAL ARTICLE DA - 920324 DP - 1991 Sep IS - 0034-5288 TA - Res Vet Sci PG - 133-40 SB - M CY - ENGLAND IP - 2 VI - 51 JC - R7D AA - Author EM - 9205 AB - Serum bile acid concentrations were measured in 41 clinically healthy cattle of different breeds. There was no diurnal variation in values and age and sex had no effect. There was no significant difference between serum and plasma bile acid concentrations in clinically healthy cattle. Serum bile acids were stable on storage at -20 degrees C. The total serum bile acid concentrations, together with other tests of hepatic disease, were evaluated in cattle with various types of hepatobiliary disease (hepatic lipidosis, hepatic abscessation, leptospirosis, biliary calculi, fascioliasis), respiratory, cardiovascular and infectious diseases, and in various other conditions not affecting the liver. Total serum bile acids were the most specific and sensitive indicators of a wide variety of hepatic diseases and were significantly correlated with the degree of clinical illness. AD - Department of Veterinary Clinical Science, Leahurst, University of Liverpool, Neston, South Wirral. PMID- 1788477 SO - Res Vet Sci 1991 Sep;51(2):133-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 92084287 AU - Zhao L AU - Yang B AU - Li S AU - Zhou Q TI - [Plasma PGI2 and TXA2 levels on a model of PDH in leptospirosis] LA - Chi MH - Animal MH - Disease Models, Animal MH - English Abstract MH - Epoprostenol/*blood MH - Guinea Pigs MH - Hemorrhage/*blood MH - Lung Diseases/*blood MH - Thromboxane B2/*blood MH - Weil's Disease/*blood MH - 6-Ketoprostaglandin F1 alpha/blood RN - 35121-78-9 (Epoprostenol) RN - 54397-85-2 (Thromboxane B2) RN - 58962-34-8 (6-Ketoprostaglandin F1 alpha) PT - JOURNAL ARTICLE DA - 920123 DP - 1991 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 253-5 CY - CHINA IP - 3 VI - 22 JC - GEB AA - Author EM - 9203 AB - Guinea pigs were intravenously injected with icterhemorrhagiae serogroup Lai serovar strain 017 leptospirosis to model the pulmonary diffuse hemorrhage (PDH) in leptospirosis. Thirty-eight hours after the injection, the jugular arteries were catheterized to collect blood sample. The plasma was prepared for radioimmunoassay of TXB2 and 6-keto- PGF1a, the stable metabolites of TXA2 and PGI2 respectively. The plasma level of TXB2 in the experimental group, 107.15 +/- 41.65 pg/ml (n = 7), almost doubled that of the control, 54.05 +/- 12.93 pg/ml (n = 7), with significant difference (P less than 0.01); meanwhile, no significant difference was observed of 6-keto-PGF1a, 67.97 +/- 16.89 pg/ml (n = 6) vs. 98.06 +/- 40.63 pg/ml (n = 9) with P greater than 0.1. The fact that TXA2 causes vasoconstriction and increases vessel permeability suggests that TXA2 elevation should play a role in the mechanism of PDH in leptospirosis. PMID- 1748406 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1991 Sep;22(3):253-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 92084285 AU - Xiao J AU - Dai B TI - [Construction of gene bank of L. interrogans serovar lai and cloning of homological sequences of virulent leptospirosis] LA - Chi MH - Cloning, Molecular MH - *DNA, Bacterial MH - DNA, Recombinant MH - English Abstract MH - *Gene Library MH - Leptospira interrogans/*genetics MH - Plasmids/genetics MH - *Sequence Homology, Nucleic Acid MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) RN - 0 (DNA, Recombinant) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 920123 DP - 1991 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 245-8 CY - CHINA IP - 3 VI - 22 JC - GEB AA - Author EM - 9203 AB - A gene bank of the main pathogen of pulmonary diffuse haemorrhage type leptospirosis (PDH), L. interrogans serovar lai strain 017, was first constructed with plasmid vector pUC9, which contained 610 recombinant clones and laid the foundation for further investigation of molecular characteristics of leptospires with strong virulence. Recombinant plasmids which have homological sequences of pathogenic leptospires were screened from the gene bank. A recombinant plasmid, designated pCX7, could detect 1.7 kb fragment of strain 017, 9.0 kb of strain 601 and 30.0 kb of strain 610 respectively without cross hybridization with nonvirulent leptospires such as L. biflexa strain Patoc I and Leptonema illini. pCX9, another recombinant plasmid, could detect 1.9 kb fragment of strain 017 and had no hybridization with other pathogenic or nonpathogenic leptospires. The results showed that the degree of homology between pathogenic and non-pathogenic leptospires was very low and the degree of homology was very high among the pathogenic leptospires. PMID- 1748405 CU - 92 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1991 Sep;22(3):245-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 92142213 AU - Ramos-Filho CF AU - Rodrigues KM AU - Martins FS TI - Leptospirosis, renal failure and raised amylase levels [letter; comment] LA - Eng MH - Amylases/*blood MH - Enzyme Tests MH - Human MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/complications/*diagnosis RN - EC 3.2.1.- (Amylases) PT - COMMENT PT - LETTER DA - 920310 DP - 1991 Sep-Oct IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 698-9 SB - M CY - ENGLAND IP - 5 VI - 85 JC - WBU EM - 9205 CM - Comment on: Trans R Soc Trop Med Hyg 1990 May-Jun;84(3):419-21 RO - M:LC1 PMID- 1723551 LR - 920625 CU - 95 SO - Trans R Soc Trop Med Hyg 1991 Sep-Oct;85(5):698-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 92084286 AU - Wu N AU - Cheng S AU - Li S AU - Dai B TI - [Analysis of leptospiral deoxyribonucleic acids by restriction endonucleases] LA - Chi MH - DNA Restriction Enzymes MH - DNA, Bacterial/*analysis MH - English Abstract MH - Leptospira interrogans/*classification/isolation & purification MH - Restriction Mapping RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 920123 DP - 1991 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 249-52 CY - CHINA IP - 3 VI - 22 JC - GEB AA - Author EM - 9203 AB - For the application of restriction endonuclease analysis in typing and identifying leptospira, we selected some serovars and isolates, and analysed preliminarily their DNA with four restriction enzymes, EcoR I, Bgl II, Hha I, and Hind III. The DNA samples were isolated from the reference strains and isolates as follows: Serovar lai 56601, 017 (the virulent strain for PDH model of guinea pig), Serovar autumnalis 56606, Serovar manhao II 67020, and isolates 87112 and 87369. Each 2 micrograms of DNA was digested with 20mu of restriction enzyme at 37 degrees C for 2h and electrophoresed in 0.8% agarose gel. The gels were stained in ethidium bromide and photographed with UV light. In our experiments, apparently different restriction patterns of serovar lai 017 were observed with four restriction enzymes. Serovar lai, serovar autumnalis and serovar manhao II showed different patterns with EcoR I, especially in high molecular regions. We also observed in serovar lai 017 a distinct 10.5kb band which was obscure in 56601, the reference strain of serovar lai, after EcoR I digestion. The three serovars showed some delicate differences in Hind III restriction pattern. The two isolates from Apodemus agrarius in Sichuan (1987) 87112 and 87369 had patterns identical to those of serovar lai 56601, 017 with EcoR I, and 87112 also had a pattern identical to 56601, 017 with Hind III. Our results indicate that selected three serovars can be identified by analysis of their DNA with EcoR I and Hind III. It is suggested that restriction endonuclease analysis be a good method in typing and identify leptospira and in studying the differences of special DNA molecules. PMID- 1660846 CU - 93 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1991 Sep;22(3):249-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 92056437 AU - Kuiken T AU - van Dijk JE AU - Terpstra WJ AU - Bokhout BA TI - The role of the common vole (Microtus arvalis) in the epidemiology of bovine infection with Leptospira interrogans serovar hardjo. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/blood MH - Cattle MH - Cattle Diseases/*epidemiology/transmission MH - *Disease Reservoirs MH - Female MH - Leptospira interrogans/immunology/isolation & purification MH - Male MH - Microtinae/*microbiology MH - Nephritis, Interstitial/microbiology/veterinary MH - Rodent Diseases/microbiology/*transmission MH - Weil's Disease/epidemiology/transmission/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 911211 DP - 1991 Aug 30 IS - 0378-1135 TA - Vet Microbiol PG - 353-61 SB - M CY - NETHERLANDS IP - 4 VI - 28 JC - XBW AA - Author EM - 9202 AB - Control of leptospirosis in cattle depends on the presence of other possible maintenance hosts, with which cattle may have contact. Twenty- seven common voles (Microtus arvalis) were trapped on a dairy farm where the cattle were infected with Leptospira interrogans serovar hardjo (hardjo). In the sera of 11 voles, titres greater than or equal to 100 against serogroup Grippotyphosa were measured with the microscopical agglutination test (MAT). From 8 of these 11 voles, which also showed interstitial lymphoplasmacellular nephritis, Leptospira interrogans serovar grippotyphosa was isolated. We found no evidence that the common vole is a maintenance host for hardjo in this biotope. AD - Central Veterinary Institute, Lelystad, Netherlands. PMID- 1949549 SO - Vet Microbiol 1991 Aug 30;28(4):353-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 92024014 AU - Bennett RM TI - A survey of dairy farmers' decisions concerning the control of leptospirosis. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - *Dairying MH - England MH - Female MH - Human MH - *Leptospira interrogans MH - Leptospirosis/prevention & control/*veterinary MH - Questionnaires MH - Risk Factors MH - Wales PT - JOURNAL ARTICLE DA - 911114 DP - 1991 Aug 10 IS - 0042-4900 TA - Vet Rec PG - 118 SB - M CY - ENGLAND IP - 6 VI - 129 JC - XBS EM - 9201 AD - Department of Agricultural Economics and Management, University of Reading. PMID- 1926731 SO - Vet Rec 1991 Aug 10;129(6):118 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 92034956 AU - Zhao M TI - [The serogroup and serotype distribution of Leptospira in Sichuan Province from 1958-1987] LA - Chi MH - Animal MH - China MH - Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira/classification MH - Leptospira interrogans/*classification MH - Muridae MH - Ranidae MH - Serotyping PT - JOURNAL ARTICLE DA - 911211 DP - 1991 Aug IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 226-30 CY - CHINA IP - 4 VI - 12 JC - CQG AA - Author EM - 9202 AB - This paper summarized the serogroup and serotype distribution of 7,560 strains Leptospira in Sichuan province from 1958 to 1987. At present, Leptospira 16 serogroup and 35 serotype have been found. The Icterohaemorrhagiae group Lai type is the major and stable serogroup and serotype in patients. We have proved that Rodents insectivores and domestic animals are the main reservoir host. The former carries Icterohaemorrhagiae group and the latter carries Pomona group. The serotype carried on the reservoir animal Apodemus agrarius is mostly Icterohaemorrhagiae Lai and is the principal infection source of Leptospirosis in Sichuan province. In addition, this paper discussed the reason of main serogroup change, the possible role of frog as an infection source of Hebdomadis Leptospirosis. AD - Sanitary and Anti-epidemic Station of Sichuan Province, Chengdu. PMID- 1934046 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1991 Aug;12(4):226-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 92011082 AU - Nielsen JN AU - Cochran GK AU - Cassells JA AU - Hanson LE TI - Leptospira interrogans serovar bratislava infection in two dogs [see comments] LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Bacteriuria/microbiology/veterinary MH - Case Report MH - *Dog Diseases/microbiology MH - Dogs MH - Leptospira interrogans/immunology/*isolation & purification MH - Male MH - Support, U.S. Gov't, Non-P.H.S. MH - Weil's Disease/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 911119 DP - 1991 Aug 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 351-2 SB - M CY - UNITED STATES IP - 3 VI - 199 JC - HAV AA - Author EM - 9201 AB - Two dogs with clinical histories suggestive of leptospirosis were examined serologically and culturally for evidence of leptospiral infection. Antibodies to Leptospira interrogans serovar bratislava were detected in serum from one dog, and the organism was isolated from urine of that dog. In a serologic survey of dogs in the state of Illinois, reactor rates to bratislava were higher than those to canicola or icterohaemorrhagiae. In cases of suspect canine leptospirosis, serovars such as bratislava, not contained in canine vaccines, should be considered in a differential diagnosis. AD - School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907. CM - Comment in: J Am Vet Med Assoc 1991 Nov 15;199(10):1239 RO - M:LC1 PMID- 1917641 LR - 920720 SO - J Am Vet Med Assoc 1991 Aug 1;199(3):351-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 91348134 AU - Chapman AJ AU - Everard CO AU - Faine S AU - Adler B TI - Antigens recognized by the human immune response to severe leptospirosis in Barbados. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*biosynthesis MH - Antigens, Bacterial/*immunology MH - Bacterial Outer Membrane Proteins/immunology MH - Bacterial Proteins/analysis/immunology MH - Barbados MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel MH - Human MH - IgG/biosynthesis MH - IgM/biosynthesis MH - Immunoblotting MH - Immunoenzyme Techniques MH - Leptospira interrogans/analysis/*immunology MH - Lipopolysaccharides/analysis MH - Support, Non-U.S. Gov't MH - Weil's Disease/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Bacterial Proteins) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 910930 DP - 1991 Aug IS - 0950-2688 TA - Epidemiol Infect PG - 143-55 SB - M CY - ENGLAND IP - 1 VI - 107 JC - EPI AA - Author EM - 9112 AB - Serum samples obtained from patients hospitalized in Barbados with severe leptospirosis were tested by the microscopic agglutination test (MAT), enzyme immunoassay (EIA) and immunoblotting with leptospires that had been isolated from these patients. While serum samples taken a few days after onset of symptoms often showed no apparent correlation between MAT and EIA, later sequential serum samples produced similar profiles in both tests during the course of infection. Immunoblotting sonicate from Leptospira interrogans serovars arborea, copenhageni and bim with patients' sera, revealed reactions with a number of bands that corresponded with outer envelope components. These components included lipopolysaccharide (LPS), flagella and other outer membrane proteins, in addition to a low-molecular-weight (MW) carbohydrate cross-reactive with members of the Leptospiraceae. IgM antibodies elicited in the first to second week after infection reacted mainly with LPS and the low-MW cross-reactive carbohydrate. Comparative analysis of isolates of the same serovar by sodium dodecyl sulphate polyacrylamide gel electrophoresis and immunoblotting showed that while two serovar arborea isolates were identical, serovar bim isolates differed significantly from each other. This difference was also observed in comparative MAT testing. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 1879481 CU - 91 SO - Epidemiol Infect 1991 Aug;107(1):143-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 91310335 AU - Blanchard-Channell M AU - Stott JL TI - Characterization of Borrelia coriaceae antigens with monoclonal antibodies. LA - Eng MH - Animal MH - Antibodies, Monoclonal/*immunology MH - Antibody Specificity MH - Antigens, Bacterial/*immunology MH - Blotting, Western MH - Borrelia/*immunology MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique MH - Mice MH - Mice, Inbred BALB C MH - Microscopy, Immunoelectron MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 910823 DP - 1991 Aug IS - 0019-9567 TA - Infect Immun PG - 2790-8 SB - M SB - X CY - UNITED STATES IP - 8 VI - 59 JC - GO7 AA - Author EM - 9110 AB - Three monoclonal antibodies (F6F3, F6B11, and F6B3) were developed against Borrelia coriaceae antigens. All three antibodies appeared to be specific for this species and did not cross-react with Borrelia burgdorferi (strains B31 and IRS), Borrelia hermsii, Borrelia anserina, Leptospira interrogans serovar hardjo, or Treponema hyodysenteriae, as determined by indirect fluorescent antibody staining, enzyme-linked immunosorbent assay, and Western immunoblot analysis. Only one of these antibodies, F6B3, bound to spirochetes present in organ smears from the argasid tick, Ornithodoros coriaceus. The antigens recognized by F6F3, F6B11, and F6B3 have apparent molecular weights of ca. 37,000, 35,000, and 16,000, respectively, as determined by Western blot analysis. Antigens were analyzed by immune electron microscopy as well as Western blot and indirect fluorescent antibody staining analysis of spirochetes after enzyme (trypsin and protease K) and detergent (Triton X-100) treatments. These studies suggest that all three antigens are integral membrane proteins. The characteristics of the 37K and 35K proteins are consistent with the outer surface proteins of B. burgdorferi (OSP A and OSP B) described by Barbour et al. (A. G. Barbour, S. L. Tessier, and S. F. Hayes, Infect. Immun. 45:94-100, 1984), while data regarding the 16K protein are less conclusive but may suggest a cytoplasmic membrane location. We suggest that the 37K, 35K, and 16K antigens be designated integral membrane proteins A, B, and C, respectively, as a result of these studies. AD - Department of Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis 95616. PMID- 1855995 CU - 91 SO - Infect Immun 1991 Aug;59(8):2790-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 92075120 AU - Gravekamp C AU - Korver H AU - Montgomery J AU - Everard CO AU - Carrington D AU - Ellis WA AU - Terpstra WJ TI - Leptospires isolated from toads and frogs on the Island of Barbados. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Monoclonal/immunology MH - Barbados MH - Bufo marinus/*microbiology MH - DNA, Bacterial/analysis MH - Kidney/microbiology MH - Leptospira interrogans/classification/genetics/*isolation & purification MH - Ranidae/*microbiology MH - Restriction Mapping MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 920110 DP - 1991 Aug IS - 0934-8840 TA - Zentralbl Bakteriol PG - 403-11 SB - M CY - GERMANY IP - 3 VI - 275 JC - BD7 AA - Author EM - 9203 AB - Four pathogenic strains of leptospires were isolated from the kidneys of toads (Bufo marinus) and seven from frogs (Eleutherodactylus johnstonei). Isolates from two toads and one frog belonged to serovar bim, the causative agent of most cases of severe leptospirosis on Barbados. The other eight strains belonged to a new serovar within the Australis serogroup. The name bajan is proposed for this new serovar of Leptospira interrogans. AD - WHO/FAO Collaborating Center for Reference and Research on Leptospirosis, Royal Tropical Institute, Amsterdam, The Netherlands. RO - M:CNR PMID- 1741925 LR - 970218 SO - Zentralbl Bakteriol 1991 Aug;275(3):403-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 92075109 AU - Cousins DV AU - Robertson GM AU - Parkinson J AU - Richards RB TI - Use of the enzyme linked immunosorbent assay (ELISA) to detect the IgM and IgG antibody response to Leptospira interrogans Serovar hardjo in pregnant ewes. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*biosynthesis/blood MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - IgG/biosynthesis/blood MH - IgM/biosynthesis/blood MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/pathology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/immunology/pathology/*veterinary MH - Sheep MH - Sheep Diseases/*immunology/pathology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (IgG) RN - 0 (IgM) PT - JOURNAL ARTICLE DA - 920110 DP - 1991 Aug IS - 0934-8840 TA - Zentralbl Bakteriol PG - 335-42 SB - M CY - GERMANY IP - 3 VI - 275 JC - BD7 AA - Author EM - 9203 AB - Fourteen pregnant ewes were inoculated with Leptospira interrogans serovar hardjo via intramuscular injection or inoculation via the conjunctiva. The serological response to inoculation detected by the microscopic agglutination test was compared to IgM and IgG antibody levels detected by enzyme linked immunosorbent assay. Intramuscular injection produced a better serological response than conjunctival inoculation. The mean IgM response was short lived whereas the IgG antibody response and the MAT persisted for much longer. The IgM antibody levels may be useful as an indicator of recent exposure. Although leptospiruria was not established in any of the animals, 6 of the 14 pregnant ewes failed to rear a healthy lamb. AD - Animal Health Laboratories, Department of Agriculture, South Perth, Western Australia. RO - M:CNR PMID- 1741914 LR - 970218 SO - Zentralbl Bakteriol 1991 Aug;275(3):335-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 92032018 AU - Asai T AU - Kinjo T AU - Minamoto N AU - Sugiyama M AU - Matsubayashi N AU - Narama I TI - Prevalence of antibodies to five selected zoonosis agents in monkeys. LA - Eng MH - Animal MH - Antibodies/*blood MH - Antibodies, Bacterial/blood MH - Antibodies, Protozoan/blood MH - Antibodies, Viral/blood MH - Chlamydia psittaci/immunology MH - Female MH - Infection/epidemiology/*veterinary MH - Leptospira interrogans/immunology MH - *Macaca MH - Male MH - Monkey Diseases/*epidemiology MH - Polyomavirus macacae/immunology MH - Prevalence MH - Support, Non-U.S. Gov't MH - Toxoplasma/immunology MH - Yersinia pseudotuberculosis/immunology MH - Zoonoses RN - 0 (Antibodies) RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Protozoan) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 911129 DP - 1991 Aug IS - 0916-7250 TA - J Vet Med Sci PG - 553-9 SB - M CY - JAPAN IP - 4 VI - 53 JC - A27 AA - Author EM - 9202 AB - The prevalence of antibodies against 5 zoonosis agents was determined in serum samples of 443 breeding monkeys. Of the monkeys, 296 were bred or kept for a long time at R institute, and the remaining 147 were newly imported from the Philippines and kept at S institute for quarantine. Antibodies to simian virus 40 were highly prevalent at 89.1% among monkeys of R institute, whereas no antibody could be detected in those of S institute. Antibodies to Chlamydia psittaci and Yersinia pseudotuberculosis were detected in 14.4 and 11.6% at R institute, and in 9.0 and 3.5% at S institute, respectively, evidencing a significant difference (P less than 0.05) between those of the two institutes for both agents. Antibodies to Toxoplasma gondii and Leptospira interrogans were found in 3.6 and 2.9% of the overall, respectively, showing no difference in positive rates in relation to breeding place. Even in cases positive to the latter 4 zoonosis agents, the antibody titers were low. The results obtained suggest that all zoonoses tested do not seem to be so serious diseases among monkeys at the present time except simian virus 40 infection, which is highly prevalent among breeding monkeys in Japan. AD - Department of Veterinary Public Health, Faculty of Agriculture, Gifu University, Japan. PMID- 1657210 CU - 93 SO - J Vet Med Sci 1991 Aug;53(4):553-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 91312255 AU - Weinstein P AU - Cameron AS TI - Occupation-related leptospirosis in South Australia [letter] LA - Eng MH - Abattoirs MH - Adolescence MH - Adult MH - Animal MH - Comparative Study MH - Human MH - Leptospirosis/*etiology MH - Middle Age MH - Occupational Diseases/*etiology MH - Retrospective Studies MH - South Australia MH - Time Factors MH - Zoonoses/transmission PT - LETTER DA - 910826 DP - 1991 Jul 15 IS - 0025-729X TA - Med J Aust PG - 132-3 SB - M SB - X CY - AUSTRALIA IP - 2 VI - 155 JC - M26 EM - 9110 PMID- 1857299 SO - Med J Aust 1991 Jul 15;155(2):132-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 92023973 AU - Poncelet L AU - Fontaine M AU - Balligand M TI - Polymyositis associated with Leptospira australis infection in a dog [letter] LA - Eng MH - Animal MH - Case Report MH - Dog Diseases/*microbiology MH - Dogs MH - Leptospirosis/microbiology/*veterinary MH - Male MH - Myositis/microbiology/*veterinary PT - LETTER DA - 911118 DP - 1991 Jul 13 IS - 0042-4900 TA - Vet Rec PG - 40 SB - M CY - ENGLAND IP - 2 VI - 129 JC - XBS EM - 9201 PMID- 1926694 SO - Vet Rec 1991 Jul 13;129(2):40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 protein link] [1 nucleotide link] [207 medline neighbors] UI - 92065222 AU - Mitchison M AU - Rood JI AU - Faine S AU - Adler B TI - Molecular analysis of a Leptospira borgpetersenii gene encoding an endoflagellar subunit protein. LA - Eng MH - beta-Galactosidase/genetics MH - Amino Acid Sequence MH - Bacterial Proteins/*genetics MH - Base Composition MH - Base Sequence MH - Blotting, Western MH - Cloning, Molecular MH - DNA, Bacterial/chemistry/genetics MH - Escherichia coli/metabolism MH - Flagellin/*genetics/immunology MH - Gene Expression Regulation, Bacterial/physiology MH - Genes, Bacterial MH - Leptospira/*genetics MH - Molecular Sequence Data MH - Open Reading Frames/genetics MH - Promoter Regions (Genetics)/genetics MH - Restriction Mapping MH - Sequence Homology, Nucleic Acid MH - Support, Non-U.S. Gov't MH - Treponema pallidum/genetics RN - EC 3.2.1.23 (beta-Galactosidase) RN - 0 (Bacterial Proteins) RN - 0 (DNA, Bacterial) RN - 12777-81-0 (Flagellin) RN - 140470-87-7 (flaB protein) PT - JOURNAL ARTICLE DA - 920102 DP - 1991 Jul IS - 0022-1287 TA - J Gen Microbiol PG - 1529-36 SB - M CY - ENGLAND VI - 137 ( Pt 7) JC - I87 AA - Author EM - 9203 AB - A flagellin gene, flaB, from Leptospira borgpetersenii (formerly L. interrogans) serovar hardjo was cloned and expressed in Escherichia coli. Expression of the 32 kDa FlaB protein was dependent upon the lacZ promoter from pUC18. Nucleotide sequence data showed an open reading frame encoding 283 amino acid residues, corresponding to a protein of molecular mass 31.3 kDa. The G + C content of the flaB gene was 54.7 mol%. Comparison of the deduced FlaB amino acid sequence with flagellins from other bacteria revealed a high level of identity with the Treponema pallidum FlaB proteins. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 1955849 CU - 93 SI - GENBANK/M61910 SI - GENBANK/M81344 SI - GENBANK/D90254 SI - GENBANK/M55528 SI - GENBANK/M36026 SI - GENBANK/M36027 SI - GENBANK/M36028 SI - GENBANK/M36029 SI - GENBANK/M36030 SI - GENBANK/M36031 SI - GENBANK/M36032 SO - J Gen Microbiol 1991 Jul;137 ( Pt 7):1529-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 92022144 AU - O'Neil KM AU - Rickman LS AU - Lazarus AA TI - Pulmonary manifestations of leptospirosis. LA - Eng MH - Acute Disease MH - Aged MH - Case Report MH - Human MH - Leptospirosis/*complications MH - Lung Diseases/*etiology MH - Male MH - Respiratory Distress Syndrome, Adult/*etiology MH - Respiratory Insufficiency/*etiology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW OF REPORTED CASES DA - 911118 DP - 1991 Jul-Aug IS - 0162-0886 TA - Rev Infect Dis PG - 705-9 SB - M CY - UNITED STATES IP - 4 VI - 13 JC - SXN AA - Author EM - 9201 AB - Pulmonary involvement in leptospiral infection is common, usually mild, and often overlooked. When pulmonary manifestations are prominent in a patient with leptospirosis, there is the potential for diagnostic confusion. We present the case of a patient with adult respiratory distress syndrome secondary to leptospirosis and review the pulmonary manifestations of leptospiral infection. AD - Department of Internal Medicine, Portsmouth Naval Hospital, Virginia 23708. RF - 49 PMID- 1925291 SO - Rev Infect Dis 1991 Jul-Aug;13(4):705-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 92008554 AU - Everard CO AU - Baulu J AU - Carrington DG AU - Korver H AU - Terpstra WJ TI - Retention of leptospiral agglutinins and long-term response to administration of monoclonal antibodies in vervet monkeys (Cercopithecus aethiops) on Barbados. LA - Eng MH - Agglutinins/*analysis MH - Animal MH - Antibodies, Monoclonal MH - Barbados MH - Cercopithecus aethiops MH - Female MH - *Immunotherapy MH - Leptospira/*immunology MH - Leptospirosis/*immunology/therapy MH - Male MH - Support, Non-U.S. Gov't RN - 0 (Agglutinins) RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 911104 DP - 1991 Jul IS - 0392-2990 TA - Eur J Epidemiol PG - 396-402 SB - M CY - ITALY IP - 4 VI - 7 JC - ERE AA - Author EM - 9201 AB - In a study of 21 wild-caught Barbadian vervet monkeys (Cercopithecus aethiops sabaeus), naturally-acquired leptospiral agglutinins were found to persist for over five years. Groups of seropositive as well as seronegative vervets were given a placebo, or full-strength monoclonal antibodies MCA F12C3 (Icterohaemorrhagiae copenhageni), or diluted F12C3 MCAs. They were challenged 24 hours later with a suspension of highly virulent leptospires (copenhageni) administered intraperitoneally. Immunoprotection was evident in animals receiving full strength MCAs as measured by their failure to develop any substantial antibody response and by their lower geometric mean titres over a period of 142 weeks (maximum GMT of 113 compared with a maximum of 1280 in the placebo group). Diluted MCAs had little or no protective value. The serological response of the monkeys which were seropositive at capture to challenge with virulent copenhageni antigen was strongly anamnestic both in those given MCAs and those given placebo. None of the naturally or experimentally infected vervets showed clinical signs of leptospiral illness. AD - Leptospira Laboratory, St. Michael, Barbados. PMID- 1915792 SO - Eur J Epidemiol 1991 Jul;7(4):396-402 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 92004691 AU - Yukawa M TI - The Mongolian gerbil as laboratory animal for testing the potency of Leptospira antisera. LA - Eng MH - Animal MH - *Disease Models, Animal MH - *Gerbillinae MH - Immune Sera/*immunology MH - *Immunization, Passive MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*prevention & control MH - Male RN - 0 (Immune Sera) PT - JOURNAL ARTICLE DA - 911121 DP - 1991 Jul-Aug IS - 0007-1935 TA - Br Vet J PG - 390-3 CY - ENGLAND IP - 4 VI - 147 JC - B5C EM - 9201 AD - Department of Veterinary Medicine, Nihon University, Fujisawa, Japan. PMID- 1913137 SO - Br Vet J 1991 Jul-Aug;147(4):390-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 91364090 AU - Champagne MJ AU - Higgins R AU - Fairbrother JM AU - Dubreuil D TI - Detection and characterization of leptospiral antigens using a biotin/avidin double-antibody sandwich enzyme-linked immunosorbent assay and immunoblot. LA - Eng MH - Animal MH - Antigens, Bacterial/*urine MH - Avidin MH - Biotin MH - Cattle MH - Electrophoresis, Polyacrylamide Gel MH - *Enzyme-Linked Immunosorbent Assay MH - Female MH - *Immunoblotting MH - Leptospira interrogans/*immunology MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 1405-69-2 (Avidin) RN - 58-85-5 (Biotin) PT - JOURNAL ARTICLE DA - 911015 DP - 1991 Jul IS - 0830-9000 TA - Can J Vet Res PG - 239-45 SB - M CY - CANADA IP - 3 VI - 55 JC - CKL AA - Author EM - 9112 AB - A biotin/avidin double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) for the detection of antigens of Leptospira interrogans serovars in experimentally inoculated bovine urine samples was evaluated. Immunoglobulin G (IgG) from rabbits immunized with L. interrogans serovar hardjo type hardjobovis sonicated, whole cell, and formalinized-heated antigen preparations were purified by a protein A- superose column coupled to fast protein liquid chromatography, and evaluated for species specificity in the ELISA. The ELISA using each specific IgG detected as few as 10(4) leptospires of the homologous serovar hardjo diluted in phosphate-buffered saline solution with Tween 20 (PBSS-Tween 20). On immunoblot analysis of proteinase-K-digested whole cell leptospiral preparations, each IgG revealed the presence of bands specific to serovar hardjo, suggesting the presence of serovar- specific epitopes on the lipopolysaccharide molecules. The minimum number of cells of heterologous serovars pomona, grippotyphosa, bratislava, icterohaemorrhagiae and copenhageni detected by each ELISA was greater, ranging from 10(6) to 10(7). The common antigenic determinants observed on immunoblot analysis were different for each specific IgG, except for a major cross-reacting, possibly flagellar, protein doublet at approximately 36-36.5 kDa. Leptospires were equally well detected by the ELISA in both bovine urine and PBSS-Tween 20. AD - Department de pathologie et microbiologie, Faculte de Medecine veterinaire de l'Universite de Montreal, Quebec. PMID- 1889035 CU - 91 SO - Can J Vet Res 1991 Jul;55(3):239-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 91358705 AU - Pope V AU - Johnson RC TI - Effect of heat or formalin treatment of leptospires on antibody response detected by immunoblotting. LA - Eng MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Antigens, Bacterial/chemistry MH - Cross Reactions MH - Formaldehyde MH - Heat MH - Immunoblotting MH - Leptospira interrogans/classification/*immunology MH - Molecular Weight MH - Rabbits MH - Serotyping RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 50-00-0 (Formaldehyde) PT - JOURNAL ARTICLE DA - 911008 DP - 1991 Jul IS - 0095-1137 TA - J Clin Microbiol PG - 1548-50 SB - M CY - UNITED STATES IP - 7 VI - 29 JC - HSH AA - Author EM - 9112 AB - Leptospira interrogans serovar icterohaemorrhagiae RGA (RGA), live or heated at 56 degrees C for 15 min or treated with Formalin, was injected into rabbits to prepare hyperimmune serum. The pathogens L. interrogans serovars icterohaemorrhagiae RGA, icterohaemorrhagiae 1, canicola Moulton, grippotyphosa Andaman, hardjo Hardjoprajitno, and pomona Pomona and the nonpathogen Leptospina biflexa serovar patoc Patoc 1 were processed for sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and after electrophoresis they were then transferred to nitrocellulose paper. Antiserum against RGA (live, heat killed, or Formalin killed) was used on one of each of the three blots. Formalin appeared to completely eliminate antibody response to antigens with the molecular weight of 14,000 to 20,000 (14K to 20K) but did expose an antigen at approximately 23K in the pathogens only. This same band had only slight reactivity when antiserum against heat-killed RGA was used. Heating also eliminated cross-reactivity in the 19K to 30K range and partially degraded bands in the 14K to 20K region so that one broad band rather than several discrete bands appeared. The three antiserum specimens cross-reacted with all of the serovars tested, but fewer antigens of grippotyphosa and hardjo reacted with the antisera. Against patoc, reactivity was limited primarily to the flagellar region. The most cross-reactivity was with the antiserum prepared by using live leptospires. AD - Meningitis and Special Pathogens Branch, Centers for Disease Control, Atlanta, Georgia 30333. PMID- 1885754 CU - 91 SO - J Clin Microbiol 1991 Jul;29(7):1548-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 91328337 AU - Yamashiro-Kanashiro EH AU - Benard G AU - Sato MN AU - Seguro AC AU - Duarte AJ TI - Cellular immune response analysis of patients with leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - B-Lymphocyte Subsets MH - Brazil MH - Human MH - Immunity, Cellular MH - Leptospirosis/*immunology MH - Leukocyte Count MH - Leukocytes, Mononuclear/immunology MH - Middle Age MH - Support, Non-U.S. Gov't MH - T-Lymphocyte Subsets PT - JOURNAL ARTICLE DA - 910912 DP - 1991 Jul IS - 0002-9637 TA - Am J Trop Med Hyg PG - 138-45 SB - A SB - M CY - UNITED STATES IP - 1 VI - 45 JC - 3ZQ AA - Author EM - 9111 AB - Peripheral blood mononuclear cells (PBMC) from acute leptospirosis patients with and without acute renal failure were studied in order to investigate the status of cellular immunity in this disease. We analyzed the lymphocyte subsets of leptospirosis patients by immunofluorescence and their responsiveness to the mitogens phytohemagglutinin (PHA) and pokeweed mitogen (PWM). Additionally, we investigated the effect of the patients' sera on normal PBMC proliferative response. We observed a decrease in the CD3+ and CD4+ cell subsets in patients with and without acute renal failure, or in percentage values alone in those who had recovered from renal failure. An increase in the number of B lymphocytes was observed in all patients, compared with controls. This increase in B lymphocytes was seen even in patients who had recovered from renal failure, when the number of CD3+ and CD4+ lymphocytes had already returned to normal levels. The low PHA response observed only with lymphocytes from patients with acute renal failure suggests a suppressive effect. The proliferative response to PWM was comparable to controls, even in the patients with acute renal failure. This latter result and the expansion of the B cell number could be related to leptospiral-derived factor(s). We also showed that sera from patients with and without acute renal failure exerted some inhibitory activity on normal PBMC responses to PHA and PWM. Although the redistribution of lymphocyte subsets and the serum suppressor activity were related to acute renal failure and leptospiral factor(s), we suggest that the cellular immune system was not irreversibly affected, which is compatible with the good prognosis seen in the patients studied. AD - Department of Internal Medicine, Faculdade de Medicina da Universidade de Sao Paulo, Brazil. PMID- 1867346 SO - Am J Trop Med Hyg 1991 Jul;45(1):138-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 92057296 AU - Lapshov VA AU - Bokshtein FM AU - Anan'ina IuV AU - Leokha NK AU - Sosnovtseva VP AU - Zhukova NA TI - [A small-mammal study in the northeastern Kara Kum for leptospirosis infectivity] LA - Rus MH - Agriculture MH - Animal MH - Antibodies, Bacterial/blood MH - Comparative Study MH - *Desert Climate MH - Disease Reservoirs/*veterinary MH - Disease Vectors MH - English Abstract MH - Leptospira/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Rodent Diseases/*epidemiology/immunology MH - Rodentia MH - Seasons MH - Turkmenistan/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 911217 DP - 1991 Jul IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 42-5 SB - M CY - USSR IP - 7 JC - Y9O AA - Author EM - 9202 AB - Search for natural foci of leptospirosis was carried out in 1987-1989 in humid biotopes of Tashauz Province, Turkmenistan. Such potential carriers of leptospirosis as house mice (Mus musculus) and tamarisk gerbils (Meriones tamariscinus) are widely spread in this area, and the size of their population can amount to great numbers. The sharpest fluctuations in the population size are characteristic of house mice inhabiting the shores of water collecting ponds and lakes in the regions of minimally used pastures. A moderate number of house mice was registered in spring and autumn at the area of irrigated agriculture. Only here and only in autumn a faint epizootic manifestation of the natural focus of L. grippotyphosa infection in house mice was registered for the first time in Turkmenistan. The titers in mouse blood sera, determined in the microagglutination test and the Leptospira lysis test, were 1:20 to 1:200. According to the data on the humidity and pH of the soil in the vicinity of irrigated fields, spring and summer months may be regarded as the most favorable period for the survival of leptospires in the environment. The probability of the aggravation of the epizootic situation seems to increase when irrigated fields adjoin pastures of are temporarily used as grazing ground for cattle. PMID- 1835231 CU - 92 TT - Issledovanie melkikh mlekopitaiushchikh severo-vostochnykh Karakumov na zarazhennost' leptospirozom. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1991 Jul;(7):42-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [2 nucleotide links] [204 medline neighbors] UI - 92065221 AU - Fukunaga M AU - Horie I AU - Mifuchi I AU - Takemoto M TI - Cloning, characterization and taxonomic significance of genes for the 5S ribosomal RNA of Leptonema illini strain 3055. LA - Eng MH - Base Sequence MH - Blotting, Southern MH - Cloning, Molecular MH - Comparative Study MH - DNA Probes/genetics MH - DNA, Ribosomal/*genetics MH - *Genes, Bacterial MH - Leptospira/classification/*genetics MH - Leptospiraceae/classification/*genetics MH - Molecular Sequence Data MH - Multigene Family/genetics MH - Restriction Mapping MH - RNA, Bacterial/genetics MH - RNA, Ribosomal, 5S/*genetics RN - 0 (DNA Probes) RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal, 5S) PT - JOURNAL ARTICLE DA - 920102 DP - 1991 Jul IS - 0022-1287 TA - J Gen Microbiol PG - 1523-8 SB - M CY - ENGLAND VI - 137 ( Pt 7) JC - I87 AA - Author EM - 9203 AB - The genes encoding the 5S ribosomal RNA (rRNA) for Leptonema illini strain 3055 were isolated and sequenced. The 5S RNA molecule encoded was 117 nucleotides long. The genome of strain 3055 contained two genes for 5S rRNA that were located close together. The nucleotide sequences of the Leptonema illini genes exhibited less similarity to the rRNA gene of Leptospira interrogans strain Moulton and also to those of typical eubacterial genes than did the rRNA genes of other leptospires. However, the overall secondary structure of the 5S rRNA encoded exhibited a strong similarity to that of typical eubacterial 5S rRNA. Southern hybridization of the 5S rRNA gene probe with the genomic DNA of strain 965, which is currently classified as Leptospira biflexa, showed the latter to have close similarity to that of strain 3055. The physical map of strain 965 was quite similar to that of strain 3055 and was greatly different from that of any other strains of L. biflexa. In the organization of 5S rRNA genes, strain 965 is sufficiently different from other members of the genus Leptospira to be regarded as a member of the genus Leptonema. AD - Faculty of Pharmacy and Pharmaceutical Science, University of Fukuyama, Hiroshima, Japan. PMID- 1720165 CU - 96 SI - GENBANK/D90253 SI - GENBANK/D90254 SI - GENBANK/M55528 SI - GENBANK/M36026 SI - GENBANK/M36027 SI - GENBANK/M36028 SI - GENBANK/M36029 SI - GENBANK/M36030 SI - GENBANK/M36031 SI - GENBANK/M36032 SO - J Gen Microbiol 1991 Jul;137 ( Pt 7):1523-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 92015584 AU - Vestweber JG AU - Merrill GL AU - Staats JJ AU - Veatch J TI - Serologic survey for selected microbial pathogens in bison from Kansas. LA - Eng MH - Anaplasmosis/epidemiology MH - Animal MH - Antibodies, Bacterial/*blood MH - Antibodies, Viral/*blood MH - Bacterial Infections/epidemiology/*veterinary MH - *Bison MH - Bluetongue/epidemiology MH - Bovine Virus Diarrhea-Mucosal Disease/epidemiology MH - Brucellosis/epidemiology/veterinary MH - Cattle MH - Female MH - Infectious Bovine Rhinotracheitis/epidemiology MH - Kansas/epidemiology MH - Leptospirosis/epidemiology/veterinary MH - Male MH - Virus Diseases/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 911105 DP - 1991 Jul IS - 0090-3558 TA - J Wildl Dis PG - 473-6 SB - M CY - UNITED STATES IP - 3 VI - 27 JC - KEM AA - Author EM - 9201 AB - A serologic survey was conducted on an American bison (Bison bison) herd in Kansas for antibodies against Brucella spp., Leptospira interrogans serovar canicola, pomona, grippotyphosa, icterohaemorrhagiae, and hardjo, Anaplasma spp., bluetongue virus, infectious bovine rhinotracheitis virus and bovine viral diarrhea virus. There was an increase in prevalence of bluetongue antibodies from 38% in 1987 to 100% in 1989 in animals greater than or equal to 24- mo-old. Prevalences of antibodies against the other livestock pathogens were either negative or at levels associated with previous vaccination. AD - Department of Clinical Sciences, Kansas State University, Manhattan 66506. PMID- 1656107 CU - 93 SO - J Wildl Dis 1991 Jul;27(3):473-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 91312464 AU - Huisman J AU - Gruteke P TI - [A reputed leptospirosis epidemic as a consequence of swimming in the Spokeplas] LA - Dut MH - Adult MH - Child MH - Diagnostic Errors MH - *Epidemiologic Methods MH - Human MH - Netherlands/epidemiology MH - Swimming MH - Water Microbiology MH - Weil's Disease/diagnosis/*epidemiology PT - JOURNAL ARTICLE DA - 910829 DP - 1991 Jun 22 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 1115-7 CY - NETHERLANDS IP - 25 VI - 135 JC - NUK EM - 9110 AD - Erasmus Universiteit, Rotterdam. PMID- 1857435 TT - Een vermeende epidemie van leptospirose als gevolg van zwemmen in de Spokeplas. SO - Ned Tijdschr Geneeskd 1991 Jun 22;135(25):1115-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 91361491 AU - Collares-Pereira M TI - Bovine leptospirosis in cattle in Portugal: bacteriological and serological findings. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Carrier State/epidemiology/microbiology/*veterinary MH - Cattle MH - Cattle Diseases/*epidemiology/microbiology MH - Female MH - Leptospira interrogans/*classification/immunology MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Male MH - Portugal/epidemiology MH - Prevalence MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 911007 DP - 1991 Jun 8 IS - 0042-4900 TA - Vet Rec PG - 549-50 SB - M CY - ENGLAND IP - 23 VI - 128 JC - XBS EM - 9112 AD - Instituto de Higiene e Medicina Tropical, Lisboa, Portugal. PMID- 1887549 CU - 91 SO - Vet Rec 1991 Jun 8;128(23):549-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 91294350 AU - Rugman FP AU - Pinn G AU - Palmer MF AU - Waite M AU - Hay CR TI - Anticardiolipin antibodies in leptospirosis. LA - Eng MH - Autoantibodies/*analysis MH - Cardiolipins/*immunology MH - Human MH - IgG/analysis MH - Leptospirosis/complications/*immunology RN - 0 (Autoantibodies) RN - 0 (Cardiolipins) PT - JOURNAL ARTICLE DA - 910815 DP - 1991 Jun IS - 0021-9746 TA - J Clin Pathol PG - 517-9 SB - A SB - M SB - X CY - ENGLAND IP - 6 VI - 44 JC - HT3 AA - Author EM - 9110 AB - The clinical course and serology of 16 cases of leptospirosis in an area with an unusually high endemic infection rate were studied to gain further insight into the pathology of the secondary immune phase that is typical of the disease. IgG anticardiolipin antibody concentrations were measured by immunoassay and found to be increased in eight serologically confirmed cases with severe complicated disease, compared with eight patients with relatively uncomplicated leptospirosis who had IgG anticardiolipin concentrations within the control reference range. This previously unreported association suggests that leptospira may induce vascular endothelial injury in severe cases and expose crypt antigens or induce conformational change of cell surface phospholipids. Leptospirosis may provide a model for an infective origin of some cases of the antiphospholipid syndrome. AD - University Department of Haematology, Royal Liverpool Hospital. PMID- 2066434 CU - 92 SO - J Clin Pathol 1991 Jun;44(6):517-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 91267090 AU - Cui JJ AU - Xiao GX AU - Chen TZ AU - Zhu GF AU - Sato T AU - Seki M AU - Kobayashi S AU - Arimitsu Y TI - Further evaluation of one-point microcapsule agglutination test for diagnosis of leptospirosis. LA - Eng MH - Acute Disease MH - Agglutination Tests/*methods MH - Antibodies, Bacterial/*blood MH - Chronic Disease MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Reagent Kits, Diagnostic RN - 0 (Antibodies, Bacterial) RN - 0 (Reagent Kits, Diagnostic) PT - JOURNAL ARTICLE DA - 910725 DP - 1991 Jun IS - 0950-2688 TA - Epidemiol Infect PG - 561-5 SB - M CY - ENGLAND IP - 3 VI - 106 JC - EPI AA - Author EM - 9109 AB - A total of 100 serum samples including 22 acute phase sera and 39 paired sera collected from clinically diagnosed cases of leptospirosis in Ming-shan County, Sichuan Province, China were examined by the one- point microcapsule agglutination test (MCAT), which was developed in Japan, and by conventional microscopic agglutination tests (MAT). The one-point MCAT is more reactive to IgM antibody than MAT and is superior in detecting antibodies in the early stages of the disease. AD - Chengdou Institute of Biological Products, China. PMID- 2050209 CU - 91 SO - Epidemiol Infect 1991 Jun;106(3):561-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 92029430 AU - Hookey JV AU - Palmer MF TI - A comparative investigation and identification of Leptospira interrogans serogroup icterohaemorrhagiae strains by monoclonal antibody and DNA fingerprint analyses. LA - Eng MH - Antibodies, Monoclonal/*diagnostic use MH - Comparative Study MH - *DNA Fingerprinting MH - DNA, Bacterial MH - Leptospira interrogans/*classification/genetics/immunology RN - 0 (Antibodies, Monoclonal) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 911213 DP - 1991 Jun IS - 0934-8840 TA - Zentralbl Bakteriol PG - 185-99 SB - M CY - GERMANY IP - 2 VI - 275 JC - BD7 AA - Author EM - 9202 AB - The identification of Leptospira interrogans icterohaemorrhagiae strains from a number of Reference Laboratories were confirmed using monoclonal antibody (MoAb) and DNA restriction endonuclease (EcoR1) analyses. With a few exceptions, strain fidelity was demonstrated. Three clinical isolates and one isolate from a rat (Rattus norvegicus) were identified on DNA fragment patterns and found to be similar to the reference strains, icterohaemorrhagiae copenhageni, I. "icterohaemorrhagiae" Ictero I and I. icterohaemorrhagiae RGA. AD - PHLS Leptospira Reference Laboratory, FAO/WHO Collaborating Centre, County Hospital, Hereford, U.K. RO - M:CNR PMID- 1930573 LR - 970218 SO - Zentralbl Bakteriol 1991 Jun;275(2):185-99 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 92005005 AU - Koury MC AU - Cisalpino EO AU - Rangel H de A TI - The use of methanol extract of Leptospira interrogans in complement fixation tests for leptospirosis. LA - Eng MH - Agglutination Tests MH - Alcohol, Methyl MH - Antigens, Bacterial/immunology MH - Comparative Study MH - Complement Fixation Tests/*methods MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*diagnosis MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 67-56-1 (Alcohol, Methyl) PT - JOURNAL ARTICLE DA - 911108 DP - 1991 Jun IS - 0008-4166 TA - Can J Microbiol PG - 455-8 SB - M CY - CANADA IP - 6 VI - 37 JC - CJ3 AA - Author EM - 9201 AB - Methanol extracts were obtained from L. interrogans serovars icterohaemorrhagiae and canicola and L. biflexa serovar patoc. Human sera from 167 normal individuals and 40 patients with different infectious diseases tested by complement fixation tests showed negative reactions. Sera from 100 patients with a suspicion of leptospirosis were tested by complement fixation tests and microscopic agglutination reactions. Agreement of 84% was found for those two reactions. Positive microscopic agglutination tests at a dilution 1:20-1:400 with negative complement fixation tests were observed in 5% of patients and negative microscopic agglutination with complement fixation tests in the range of 1:20-1:1280 were observed in 11% of the cases. AD - Departamento de Microbiologia, Universidade Federal de Minas Gerais, Brasil. PMID- 1913350 SO - Can J Microbiol 1991 Jun;37(6):455-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 91361730 AU - Shaginian IA AU - Anan'ina IuV AU - Tokarskaia ON AU - Grizhebovskii GM AU - Briukhanov AF AU - Ryskov AP AU - Tartakovskii IS AU - Gintsburg AL AU - Prozorovskii SV TI - [The genomic fingerprinting of the causative agents of sapronoses] LA - Rus MH - *DNA Fingerprinting MH - DNA Probes MH - DNA, Bacterial/*genetics MH - English Abstract MH - *Environmental Microbiology MH - Genes, Bacterial/*genetics MH - Genotype MH - Human MH - Legionella/*genetics/isolation & purification/pathogenicity MH - Leptospira/*genetics/isolation & purification/pathogenicity MH - Nucleic Acid Hybridization MH - Polymorphism (Genetics)/genetics MH - Vibrio cholerae/*genetics/isolation & purification/pathogenicity MH - Virulence/genetics RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 911009 DP - 1991 Jun IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 25-9 SB - M CY - USSR IP - 6 JC - Y9O AA - Author EM - 9112 AB - The genome polymorphism of the causative agents of sapronoses (Vibrio cholerae, Legionella and Leptospira) has been studied. The use of the method of genome fingerprinting [correction of dactyloscopy] has been shown to permit the differentiation of closely related strains of such causative agents. The epidemically significant strains of the causative agents of sapronoses, isolated in different geographical regions, have been found to be genotypically related, i.e., they are probably of clonal origin. Avirulent and nontoxigenic strains are genotypically heterogeneous and differ both from one another and from epidemically significant strains. Using V. cholerae as an example, the hypothesis of the appearance of potentially dangerous variants at the epidemic period in the absence of their release at the period between epidemics is considered. PMID- 1887704 CU - 92 TT - Genomnaia daktiloskopiia vozbuditelei sapronozov. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1991 Jun;(6):25-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 91311237 AU - Overstreet DS AU - Bowen MG AU - Hawkins SC AU - Roy TM TI - The respiratory complications of leptospirosis. LA - Eng MH - Case Report MH - Human MH - Leptospirosis/*complications/physiopathology MH - Male MH - Middle Age MH - Muscles/physiopathology MH - Respiratory Insufficiency/*etiology MH - Respiratory Muscles/physiopathology PT - JOURNAL ARTICLE DA - 910823 DP - 1991 Jun IS - 0023-0294 TA - J Ky Med Assoc PG - 270-3 CY - UNITED STATES IP - 6 VI - 89 JC - IV8 AA - Author EM - 9110 AB - Leptospirosis is an uncommon disease. Respiratory failure attributable to this infection is unusual, but remains a major cause of mortality. Mechanical ventilation has been required for patients with significant alveolar hemorrhage and the adult respiratory distress syndrome. We report a patient with ventilatory failure due to the severe muscle weakness associated with leptospirosis and review the pulmonary consequences of this infection. AD - Department of Internal Medicine, University of Louisville School of Medicine, KY 40292. PMID- 1856585 SO - J Ky Med Assoc 1991 Jun;89(6):270-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 92149020 AU - Moribayashi A AU - Goto N AU - Arimitsu Y AU - Himeno K AU - Tatsuki S TI - Lipids and fatty acids of Leptospira interrogans serovar copenhageni virulent strain Shibaura. LA - Eng MH - Acetone MH - Chloroform MH - Chromatography, Gas MH - Chromatography, Thin Layer MH - Fatty Acids/*analysis MH - Fatty Acids, Unsaturated/analysis MH - Leptospira interrogans/*chemistry/pathogenicity MH - Lipids/*chemistry MH - Mass Fragmentography MH - Phospholipids/chemistry MH - Virulence/physiology RN - 0 (Fatty Acids) RN - 0 (Fatty Acids, Unsaturated) RN - 0 (Lipids) RN - 0 (Phospholipids) RN - 67-64-1 (Acetone) RN - 67-66-3 (Chloroform) PT - JOURNAL ARTICLE DA - 920319 DP - 1991 Jun IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 87-97 SB - M CY - JAPAN IP - 3 VI - 44 JC - KLZ AA - Author EM - 9205 AB - Lipids and fatty acids of Leptospira interrogans serovar copenhageni virulent strain Shibaura were analyzed by thin-layer chromatography, gas-liquid chromatography, gas-mass spectrometry and infrared absorption spectrometry. The virulent cells possessed a characteristic lipid pattern consisting of free fatty acid (FFA) (41.8%), one major unidentified phospholipid (14.8%), phosphatidylethanolamine (PE) (12.9%), cholesteryl ester (CE) (9.3%), lysophosphatidylethanolamine (LPE) (4.9%) and diphosphatidyl-glycerol (DPG) (1.1%). Various fatty acids such as hexadecanoic (26.9%), hexadecenoic (15.4%), octadecenoic (26.5%) and octadecadienoic (27.4%) acids were detected in the FFA. The fatty acid composition of the major unidentified phospholipid distinctly differed from those of other lipids including PE, LPE, DPG and CE, and comprised mainly tetradecadienoic (53.6%), tetradecatrienoic (14.0%) and octadecanoic (13.8%) acids. This phospholipid with a large amount of polyunsaturated fatty acids with chain lengths of 14 carbon atoms was detected only in the lipids of the virulent cells. AD - Laboratory of Technology, National Institute of Health, Tokyo. PMID- 1784083 CU - 92 SO - Jpn J Med Sci Biol 1991 Jun;44(3):87-97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 91340610 AU - Hall WF AU - Weigel RM AU - Siegel AM AU - Wiemers JF AU - Lehman JR AU - Taft AC AU - Annelli JF TI - Prevalence of pseudorabies virus infection and associated infections in six large swine herds in Illinois. LA - Eng MH - Animal MH - Antibodies, Viral/*blood MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Herpesvirus 1, Suid/*immunology MH - Illinois/epidemiology MH - Male MH - Parity MH - Prevalence MH - Pseudorabies/complications/*epidemiology MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Swine MH - Swine Diseases/*epidemiology RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 910924 DP - 1991 Jun 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1927-31 SB - M CY - UNITED STATES IP - 11 VI - 198 JC - HAV AA - Author EM - 9111 AB - Sera were collected from 6 large farrow-to-finish swine herds infected with pseudorabies virus (PRV) in Illinois. All herds were participating in the Large Herd Cleanup Study, a USDA-initiated project to evaluate the feasibility of eradicating pseudorabies from large farms (greater than 400 sows) by use of a combination of vaccination and management changes. Herd size ranged between 425 and 1,500 breeding females. Between April and July 1990, sera for measurement of PRV antibodies were obtained from 113 to 156 sows and 112 to 162 finishing pigs (body weight greater than 70 kg)/herd. Duplicate sera from 30 sows and 30 market-weight pigs/herd were obtained for measurement of serum antibodies to the following associated organisms: swine influenza virus, transmissible gastroenteritis virus, encephalomyocarditis virus, Actinobacillus pleuropneumoniae, Eperythrozoon suis, and 6 serovars of Leptospira interrogans. Prevalence of PRV antibodies attributable to field virus infection ranged between 53.8 and 100% for sows and between 0.7 and 97.3% for finishing pigs, as determined by the appropriate differential test for the vaccine being used on each farm. In only 1 herd, PRV seroprevalence was increased with higher sow parity. For associated infections, the risk of seropositivity attributable to PRV was not significant (for most infections) on all farms and varied among farms. Thus, pseudorabies did not appear, in general, to increase susceptibility to infection with other disease agents. AD - Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana 61801. PMID- 1651912 CU - 93 SO - J Am Vet Med Assoc 1991 Jun 1;198(11):1927-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 91277171 AU - Van Eys GJ AU - Gerritsen MJ AU - Korver H AU - Schoone GJ AU - Kroon CC AU - Terpstra WJ TI - Characterization of serovars of the genus Leptospira by DNA hybridization with hardjobovis and icterohaemorrhagiae recombinant probes with special attention to serogroup sejroe. LA - Eng MH - Blotting, Southern MH - DNA Probes MH - DNA, Bacterial/*genetics MH - Human MH - Leptospira/classification/*genetics/isolation & purification MH - Leptospira interrogans/classification/genetics/isolation & purification MH - Nucleic Acid Hybridization MH - Sequence Homology, Nucleic Acid MH - Serotyping MH - Species Specificity RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 910801 DP - 1991 May IS - 0095-1137 TA - J Clin Microbiol PG - 1042-8 SB - M CY - UNITED STATES IP - 5 VI - 29 JC - HSH AA - Author EM - 9110 AB - Recombinant DNA probes derived from genomic libraries of serovars hardjobovis and icterohaemorrhagiae were applied for the characterization of leptospires. Differences in hybridization signals in combination with the banding pattern appear to provide good characteristics for strain typing. The banding patterns were easy to distinguish, since the recombinant DNA probes hybridized with a limited number of fragments. They were also indicative of genomic relationships between serovars. The probes suggested the existence of four subgroups with extensive genomic homology within the serogroup Sejroe. A number of serovars outside the serogroup Sejroe showed genomic homology with these subgroups. Amplification with the polymerase chain reaction showed a correlation with the genomic homologies demonstrated by Southern analysis. Knowledge about genomic relationships between leptospiral strains, as revealed by Southern analysis, may lead to a more rational approach for primer selection for polymerase chain reaction or cloning of particular genes. AD - N. H. Swellengrebel Laboratory of Tropical Hygiene, WHO/FAO Collaborating Centre for Reference and Research on Leptospirosis, Royal Tropical Institute, Amsterdam, The Netherlands. PMID- 2056039 CU - 92 SO - J Clin Microbiol 1991 May;29(5):1042-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 91209933 AU - Brown JA AU - LeFebvre RB AU - Pan MJ TI - Protein and antigen profiles of prevalent serovars of Leptospira interrogans. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Bacterial Proteins/*analysis MH - Bacterial Vaccines/immunology MH - Detergents/pharmacology MH - Electrophoresis, Polyacrylamide Gel MH - Immunoblotting MH - Leptospira interrogans/analysis/*immunology MH - Rabbits MH - Serotyping RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) RN - 0 (Bacterial Vaccines) RN - 0 (Detergents) PT - JOURNAL ARTICLE DA - 910528 DP - 1991 May IS - 0019-9567 TA - Infect Immun PG - 1772-7 SB - M SB - X CY - UNITED STATES IP - 5 VI - 59 JC - GO7 AA - Author EM - 9108 AB - Whole-cell and detergent-soluble proteins, enriched for outer membrane antigens, of the Leptospira interrogans serovars present in commercially available pentavalent vaccines (hardjo, pomona, icterohaemorrhagiae, grippotyphosa, and canicola) were subjected to sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotting (immunoblotting). Protein and antigenic profiles of these serovars, representing several serogroups, were compared with similar profiles of the most common North American bovine pathogen, serovar hardjo type hardjo bovis. The reference strain of serovar balcanica and a hardjoprajitno bovine field isolate (serovar hardjo) were also assayed. Coomassie blue-stained gels revealed extensive protein similarities, and Western blots demonstrated antigenic relatedness throughout the low- and high-molecular-weight regions. Possible quantitative differences in protein expression among the strains were noted, as were similarities in the protein profiles of type hardjo bovis and the balcanica reference strain. A cocktail composed of these homologous antigens may serve as an efficacious subunit vaccine for leptospirosis. AD - VM Veterinary Microbiology and Immunology, University of California, Davis 95616. PMID- 2019441 CU - 91 SO - Infect Immun 1991 May;59(5):1772-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [203 medline neighbors] UI - 91324852 AU - Woodward MJ AU - Sullivan GJ TI - Nucleotide sequence of a repetitive element isolated from Leptospira interrogans serovar hardjo type hardjo-bovis. LA - Eng MH - Base Sequence MH - Cloning, Molecular MH - DNA Insertion Elements MH - DNA, Bacterial/*genetics MH - Genes, Bacterial MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - *Repetitive Sequences, Nucleic Acid MH - Restriction Mapping MH - Sequence Homology, Nucleic Acid RN - 0 (DNA Insertion Elements) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 910906 DP - 1991 May IS - 0022-1287 TA - J Gen Microbiol PG - 1101-9 SB - M CY - ENGLAND VI - 137 ( Pt 5) JC - I87 AA - Author EM - 9111 AB - A repetitive element from the genome of Leptospira interrogans serovar hardjo type hardjo-bovis ('L. hardjo-bovis') was identified, cloned and sequenced. Similar sequences were shown by hybridization to be encoded by a further eight of 32 other leptospiral serovars tested. An undefined number of repetitive elements were located in the L. hardjo- bovis genome; sequence degeneracy of the elements was observed and no significant open reading frames were identified within the AT-rich (60%) 1467 bp repetitive element. The termini encoded a GC-rich 8 bp repeat motif and two variants showed rearrangements centred on these motifs. The nucleotide sequences of the chromosomal regions flanking the repetitive elements were determined but showed no similarities, with one exception which had a GAAC repeat directly adjacent to both termini. Similar hybridization patterns were shown by Southern transfers of L. hardjo-bovis total genomic digests probed with the repetitive element. Oligonucleotide primer pairs designed from sequences internal to the repetitive element and adjacent chromosomal regions were used in polymerase chain reaction experiments. With one primer pair all L. hardjo-bovis isolates, but no other serovar, gave identical amplified products. Evidence that the repetitive element may have derived from an acquired insertion sequence that is now inactive and chromosomally fixed is discussed. AD - Molecular Genetics Unit, Central Veterinary Laboratory, Weybridge, Surrey, UK. PMID- 1650813 CU - 93 SI - GENBANK/M57713 SI - GENBANK/S60877 SI - GENBANK/S60878 SI - GENBANK/S58761 SI - GENBANK/S58763 SI - GENBANK/S58765 SI - GENBANK/S58776 SI - GENBANK/S58778 SI - GENBANK/S58779 SI - GENBANK/S58781 SO - J Gen Microbiol 1991 May;137 ( Pt 5):1101-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 91277205 AU - Ellis WA AU - Montgomery JM AU - Thiermann AB TI - Restriction endonuclease analysis as a taxonomic tool in the study of pig isolates belonging to the Australis serogroup of Leptospira interrogans. LA - Eng MH - Animal MH - DNA Restriction Enzymes MH - DNA, Bacterial/genetics/isolation & purification MH - Electrophoresis, Agar Gel MH - Leptospira interrogans/*classification/genetics/isolation & purification MH - Serotyping MH - Species Specificity MH - Swine/microbiology RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 910801 DP - 1991 May IS - 0095-1137 TA - J Clin Microbiol PG - 957-61 SB - M CY - UNITED STATES IP - 5 VI - 29 JC - HSH AA - Author EM - 9110 AB - Restriction endonuclease analysis was performed on DNAs from the type strains of the Australis serogroup of Leptospira interrogans by using 20 restriction enzymes, and the electrophoretic patterns obtained were compared with patterns obtained from 162 Australis serogroup isolates from pigs. It proved to be a quick and reliable method for typing such strains. All of the pig isolates were identified as either serovar bratislava or muenchen. It also showed differences at the subserovar level which may be important in (i) understanding the epidemiology of the Australis serogroup, (ii) the development of suitable vaccines, and (iii) pathogenesis and pathogenicity studies. Two genotypes (B2b and M2) accounted for 92% of isolates from aborted or stillborn piglets, while a third genotype (B2a) was the only one recovered from the brains of piglets with meningitis. AD - Veterinary Research Laboratories, Belfast, Northern Ireland, United Kingdom. PMID- 1647408 CU - 93 SO - J Clin Microbiol 1991 May;29(5):957-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 91254718 AU - Fach P AU - Trap D AU - Guillou JP TI - Biotinylated probes to detect Leptospira interrogans on dot blot hybridization or by in situ hybridization. LA - Eng MH - Biotin MH - *DNA Probes MH - DNA, Bacterial/*analysis MH - Leptospira interrogans/genetics/*isolation & purification MH - *Nucleic Acid Hybridization MH - Predictive Value of Tests MH - Species Specificity RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) RN - 58-85-5 (Biotin) PT - JOURNAL ARTICLE DA - 910716 DP - 1991 May IS - 0266-8254 TA - Lett Appl Microbiol PG - 171-6 CY - ENGLAND IP - 5 VI - 12 JC - AL0 AA - Author EM - 9109 AB - Total genomic biotinylated probes which can identify leptospires by hybridization on filters or by in situ hybridization are described in this study. According to the weak G + C content of the strains studied (35-39%) and owing to the decreasing melting temperature (Tm) due to overbiotinylation, hybridization and wash temperatures were optimized at 33 degrees C and at 42 degrees C respectively. Fourteen serovars of Leptospira interrogans belonging to 11 different serogroups and three serovars of Leptospira biflexa were used in this study. Cross- hybridization results show that it is possible, by means of such probes, specifically to recognize pathogenic strains. These probes did not hybridize with the three saprophytic strains: L. buenos-aires, L. patoc and L. andamana. We also ran a total genomic probe, specific to the serovar buenos-aires which hybridizes only with homologous DNA. AD - Centre National d'Etudes Veterinaires et Alimentaires, Laboratoire Central de Recherches Veterinaires, Maisons-Alfort, France. PMID- 1367181 CU - 92 LI - B SO - Lett Appl Microbiol 1991 May;12(5):171-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 91295247 AU - Khan MA AU - Goyal SM AU - Diesch SL AU - Mech LD AU - Fritts SH TI - Seroepidemiology of leptospirosis in Minnesota wolves. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*blood MH - *Carnivora MH - Female MH - Leptospira interrogans/classification/*immunology MH - Male MH - Minnesota/epidemiology MH - Prevalence MH - Sex Factors MH - Support, U.S. Gov't, Non-P.H.S. MH - Weil's Disease/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910815 DP - 1991 Apr IS - 0090-3558 TA - J Wildl Dis PG - 248-53 SB - M CY - UNITED STATES IP - 2 VI - 27 JC - KEM AA - Author EM - 9110 AB - Serum samples (n = 457) from wolves (Canis lupus) in northern Minnesota were collected from 1972 through 1986 and were tested for antibodies against Leptospira interrogans using a microtiter agglutination test. Twelve serovars included in the study were: australis, autumnalis, ballum, bataviae, bratislava, canicola, copenhageni, grippotyphosa, hardjo, pomona, pyrogenes, and tarassovi. Fifty-two (11%) sera had antibody titers of greater than or equal to 1:50 against one or more serovars of L. interrogans. The seroprevalence of different serovars in decreasing order was: grippotyphosa, bratislava, autumnalis, canicola, pomona, ballum, pyrogenes, hardjo, and copenhageni. No antibodies were found against australis, bataviae, and tarassovi. These results indicate that L. interrogans infection may occur in wolves of Minnesota. AD - Department of Veterinary Diagnostic Investigation, College of Veterinary Medicine, University of Minnesota, St. Paul 55108. PMID- 2067045 CU - 91 SO - J Wildl Dis 1991 Apr;27(2):248-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 91218208 AU - Taylor KD AU - Turner LH AU - Everard JD TI - Leptospires in Rattus spp. on Barbados. LA - Eng MH - Animal MH - Antibodies, Bacterial/blood MH - Barbados MH - *Disease Reservoirs MH - Leptospira/immunology/isolation & purification MH - Leptospira interrogans/immunology/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - *Muridae MH - *Rats MH - Rodent Diseases/*epidemiology MH - Rural Health MH - Urban Health RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910606 DP - 1991 Apr IS - 0022-5304 TA - J Trop Med Hyg PG - 102-3 SB - M CY - ENGLAND IP - 2 VI - 94 JC - KAV AA - Author EM - 9108 AB - Among 138 Rattus norvegicus and 98 R. rattus trapped on Barbados in 1964-65 and examined for evidence of leptospiral infection, seropositivity prevalence rates were similar (34 and 30%, respectively), but isolation/dark field microscopy rates were higher in R. norvegicus (27%) than R. rattus (15%). R. norvegicus carried mainly serogroup Icterohaemorrhagiae and R. rattus mainly serogroup Autumnalis. These two serogroups cause 90% of severe human leptospirosis on the island. AD - Leptospira Laboratory, St Michael, Barbados. PMID- 2023284 CU - 91 SO - J Trop Med Hyg 1991 Apr;94(2):102-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 91169638 AU - Stamm LV AU - Gherardini FC AU - Parrish EA AU - Moomaw CR TI - Heat shock response of spirochetes. LA - Eng MH - Borrelia burgdorferi/genetics/*metabolism MH - Heat-Shock Proteins/*biosynthesis/genetics MH - Leptospira interrogans/genetics/*metabolism MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Treponema pallidum/genetics/*metabolism RN - 0 (Heat-Shock Proteins) PT - JOURNAL ARTICLE ID - AI24976/AI/NIAID ID - AI15036/AI/NIAID DA - 910425 DP - 1991 Apr IS - 0019-9567 TA - Infect Immun PG - 1572-5 SB - M SB - X CY - UNITED STATES IP - 4 VI - 59 JC - GO7 AA - Author EM - 9106 AB - We examined the heat shock response of the pathogenic spirochetes Treponema pallidum, Borrelia burgdorferi, and Leptospira interrogans and certain saprophytic spirochetes. Cellular proteins synthesized after shifts to higher temperatures were [35S]methionine labeled and analyzed by gel electrophoresis and fluorography. Only T. pallidum failed to exhibit an obvious heat shock response. GroEL and DnaK homologs were identified in the various species, although these proteins were not thermoinducible in T. pallidum or Treponema denticola. DNA hybridization studies indicate that spirochetal groEL and dnaK genes are highly conserved. AD - Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599-7400. PMID- 2004832 CU - 91 SO - Infect Immun 1991 Apr;59(4):1572-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 92004995 AU - Masuzawa T AU - Hashiguchi Y AU - Nakamura R AU - Suzuki R AU - Shimizu T AU - Iwamoto Y AU - Morita T AU - Yanagihara Y TI - Experimental lethal infection of Leptospira interrogans in mice treated with cyclophosphamide. LA - Eng MH - Animal MH - Comparative Study MH - *Cyclophosphamide MH - Disease Models, Animal MH - Hamsters MH - *Immunosuppression MH - Kidney/microbiology MH - Leptospira interrogans/*pathogenicity MH - Male MH - Mice MH - Mice, Inbred BALB C MH - Support, Non-U.S. Gov't MH - Virulence MH - Weil's Disease/immunology/*microbiology RN - 50-18-0 (Cyclophosphamide) PT - JOURNAL ARTICLE DA - 911107 DP - 1991 Apr IS - 0008-4166 TA - Can J Microbiol PG - 312-5 SB - M CY - CANADA IP - 4 VI - 37 JC - CJ3 AA - Author EM - 9201 AB - After preadministration of cyclophosphamide (300 mg/kg), BALB/c mice were lethally infected with Leptospira interrogans serovar lai and a virulent strain of Leptospira interrogans serovar copenhageni, and leptospiral cells were detected in both kidneys of infected mice by indirect immunofluorescent assay. Nonpathogenic leptospirae, Leptospira biflexa serovar patoc, Leptonema illini, and an avirulent strain of L. interrogans serovar copenhageni, were not parasitic to the mice treated with cyclophosphamide. The cyclophosphamide-treated mice were protected from the homologous leptospiral infection by passive immunization with anti-leptospiral monoclonal antibody or with rabbit antiserum and by active immunization with lyophilized organisms or with protective antigen. The results of active immunization in mice treated with cyclophosphamide agreed well with those in nontreated hamsters, which were sensitive to the organisms. Furthermore, these experiments were reproducible with any lot of cyclophosphamide used. These results indicated that cyclophosphamide-treated mice can be used in the experimental infection of Leptospira in place of hamsters or guinea pigs. AD - Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka, Japan. PMID- 1913341 SO - Can J Microbiol 1991 Apr;37(4):312-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 91375294 AU - Zuerner RL AU - Knudtson W AU - Bolin CA AU - Trueba G TI - Characterization of outer membrane and secreted proteins of Leptospira interrogans serovar pomona. LA - Eng MH - Animal MH - Bacterial Outer Membrane Proteins/*analysis/immunology MH - Bacterial Proteins/*secretion MH - Heat MH - Hemolysins/analysis/immunology/secretion MH - Leptospira interrogans/*analysis/growth & development/metabolism MH - Membrane Proteins/isolation & purification MH - Molecular Weight MH - Swine RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Bacterial Proteins) RN - 0 (Hemolysins) RN - 0 (Membrane Proteins) PT - JOURNAL ARTICLE DA - 911021 DP - 1991 Apr IS - 0882-4010 TA - Microb Pathog PG - 311-22 SB - M CY - ENGLAND IP - 4 VI - 10 JC - MIC AA - Author EM - 9112 AB - Outer membrane and secreted proteins were isolated from Leptospira interrogans serovar pomona and characterized by sodium dodecyl sulfate polyacrylamide gel electrophoresis, immunoblot and radioimmunoprecipitation techniques. The L. interrogans outer membranes were extracted with Triton X-114 and contained several proteins. The major cellular protein with a molecular mass of 31 kDa was associated exclusively with the L. interrogans outer membrane. Using a whole cell immunoprecipitation method, five hydrophobic, Triton X-114 extractable proteins (22, 26, 31, 36 and 42 kDa) were exposed on the surface of L. interrogans. The 31 kDa protein was heat labile and was a potent antigen in animals experimentally infected with L. interrogans serovar pomona. Several proteins were secreted by L. interrogans including a 60 kDa protein tentatively identified as the L. interrogans hemolysin. AD - National Animal Disease Center, Agricultural Research Service, Ames, Iowa 50010. PMID- 1895930 CU - 92 SO - Microb Pathog 1991 Apr;10(4):311-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 91370113 AU - Bolin CA AU - Cassells JA AU - Hill HT AU - Frantz JC AU - Nielsen JN TI - Reproductive failure associated with Leptospira interrogans serovar bratislava infection of swine. LA - Eng MH - Abortion, Veterinary/*diagnosis MH - Animal MH - Antibodies, Bacterial/analysis/blood MH - Female MH - Fetal Blood/microbiology MH - Fetal Death/diagnosis/*veterinary MH - Fluorescent Antibody Technique MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - Pregnancy MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*diagnosis MH - Urine/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 911018 DP - 1991 Apr IS - 1040-6387 TA - J Vet Diagn Invest PG - 152-4 SB - M CY - UNITED STATES IP - 2 VI - 3 JC - A2D AA - Author EM - 9112 AB - Specimens from 17 swine herds experiencing reproductive failure were examined for Leptospira interrogans serovar bratislava. Clinical signs observed in these herds included stillborn pigs, weak neonatal pigs, and abortion. Diagnostic tests used to determine L. interrogans serovar bratislava infection were bacteriologic culture, serologic assays to detect antibodies, and immunofluorescence. Examination of fetal serum for antibodies against serovar bratislava and a fluorescent antibody test were the most practical diagnostic procedures. AD - National Animal Disease Center, USDA, Ames, IA 50010. PMID- 1892932 CU - 91 SO - J Vet Diagn Invest 1991 Apr;3(2):152-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 91370112 AU - Donahue JM AU - Smith BJ AU - Redmon KJ AU - Donahue JK TI - Diagnosis and prevalence of leptospira infection in aborted and stillborn horses. LA - Eng MH - Abortion, Veterinary/diagnosis/epidemiology/*microbiology MH - Agglutination Tests MH - Animal MH - Breeding MH - Female MH - Fetal Death/diagnosis/epidemiology/*microbiology MH - Fluorescent Antibody Technique MH - Horse Diseases/*diagnosis/microbiology MH - Horses MH - Kentucky/epidemiology MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/diagnosis/epidemiology/microbiology/*veterinary MH - Pregnancy MH - Prevalence MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 911018 DP - 1991 Apr IS - 1040-6387 TA - J Vet Diagn Invest PG - 148-51 SB - M CY - UNITED STATES IP - 2 VI - 3 JC - A2D AA - Author EM - 9112 AB - A study was conducted to evaluate a recently available fluorescent antibody test (FAT) conjugate for the detection of leptospires in tissues of aborted and stillborn horses, to determine the leptospira antibody titers and compare serologic test results with FAT results, and to determine the prevalence of leptospira-induced abortions and stillbirths in the equine population of central Kentucky. From July 1, 1988 through June 30, 1989, 15 (2.5%) of 594 submissions (fetuses, stillborn foals, and/or placentas) were diagnosed as leptospirosis by the FAT (14 of 15 tested) and/or microscopic agglutination test (12 of 14 tested). Of the 12 serologically positive fetal fluids, 10 had high tigers against Leptospira interrogans serovar pomona and 2 against serovar grippotyphosa. AD - Department of Veterinary Science, College of Agriculture, University of Kentucky, Lexington 40511. PMID- 1892931 SO - J Vet Diagn Invest 1991 Apr;3(2):148-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 91365882 AU - Lupidi R AU - Cinco M AU - Balanzin D AU - Delprete E AU - Varaldo PE TI - Serological follow-up of patients involved in a localized outbreak of leptospirosis. LA - Eng MH - Adult MH - Aged MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/immunology MH - Disease Outbreaks MH - Drinking MH - Female MH - Follow-Up Studies MH - Hedgehogs MH - Human MH - IgG/immunology MH - IgM/immunology MH - Italy/epidemiology MH - Leptospira interrogans/immunology/*isolation & purification MH - Male MH - Middle Age MH - Support, Non-U.S. Gov't MH - Water Microbiology MH - Weil's Disease/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 911015 DP - 1991 Apr IS - 0095-1137 TA - J Clin Microbiol PG - 805-9 SB - M CY - UNITED STATES IP - 4 VI - 29 JC - HSH AA - Author EM - 9112 AB - Eighteen patients involved in a localized outbreak of leptospirosis were subjected to a serological follow-up study over a 5-year period. Four distinct sets of sera from all patients and a fifth sample obtained from 10 of them were examined by the microscopic agglutination test (MAT) for demonstration of leptospiral antibodies. The test was carried out by using live leptospires from reference strains of 17 Leptospira interrogans serovars known to occur in Italy. In all cases, the highest titers of agglutinins were recorded against one or more of the three Australis group serovars tested (australis, bratislava, and lora). The highest antibody levels were reached soon after the acute phase of infection in some patients but only after some months in others. Titers then tended to recede with varying rapidity, but titers against the Australis group serovars were still detectable in some patients after 5 years. Coagglutinins against serovars of other serogroups were detected, generally at low levels, in the early sets of sera of most patients, but tended to disappear in the late-set sera. Specific immunoglobulin M (IgM) and IgG against the three Australis group serovars were determined in most serum samples from 16 patients by solid-phase enzyme immunoassay (EIA). In general, EIA titers were considerably lower than MAT titers, but there was a certain patient-to- patient variability in both the IgM/IgG ratio and the evolution and persistence of the two immunoglobulin classes.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Institute of Microbiology, University of Ancona Medical School, Italy. PMID- 1890181 CU - 91 SO - J Clin Microbiol 1991 Apr;29(4):805-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 91352980 AU - Dom PP AU - Haesebrouck F AU - Vandermeersch R AU - Descamps J AU - Van Ommeslaeghe K TI - Prevalence of Leptospira interrogans serovar hardjo antibodies in milk in Belgian dairy herds. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Belgium/epidemiology MH - Cattle MH - Cattle Diseases/*epidemiology MH - Enzyme-Linked Immunosorbent Assay MH - Leptospira interrogans/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Milk/*immunology MH - Prevalence RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910930 DP - 1991 Apr IS - 0165-2176 TA - Vet Q PG - 118-20 SB - M CY - NETHERLANDS IP - 2 VI - 13 JC - XBT AA - Author EM - 9112 AB - Pooled milk samples were collected from 2000 Belgian dairy herds in the autumn of 1989. Antibodies against Leptospira interrogans serovar hardjo were detected in 9.2% of the herds, with the incidence being higher in the southern part of the country. AD - Laboratory of Veterinary Bacteriology, Faculty of Veterinary Medicine, University of Ghent, Belgium. PMID- 1882491 CU - 91 SO - Vet Q 1991 Apr;13(2):118-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 92253803 AU - Suarez Hernandez M AU - Bustelo Aguila J AU - Perez Gonzalez L AU - Gorgoy Gonzalez V TI - [Outbreak of leptospirosis, predominantly meningoencephalitic, among children in the municipality of Moron] LA - Spa MH - Animal MH - Child MH - Cuba/epidemiology MH - *Disease Outbreaks MH - Dog Diseases/microbiology MH - Dogs/microbiology MH - English Abstract MH - Human MH - Leptospira canicola/*isolation & purification MH - Leptospirosis/*epidemiology/microbiology/transmission/veterinary MH - Meningoencephalitis/*epidemiology/microbiology MH - Swimming MH - Water Microbiology MH - Water Pollution PT - JOURNAL ARTICLE DA - 920610 DP - 1991 Apr-Aug IS - 0375-0760 TA - Rev Cubana Med Trop PG - 136-9 CY - CUBA IP - 2 VI - 43 JC - RPX AA - Author EM - 9208 AB - A description is made of a leptospirosis outbreak in children who bathed in the Cimarron Channel in Moron. Ciego de Avila. The outbreak started on September 25 and ended on October 20, 1986. Six cases were reported, of which four had meningoencephalic appearance. Ages ranged from 8 to 13 years. Fever, cephalalgia, arthralgia and myalgia were the most common signs and symptoms in the confirmed cases. All the patients were positive to Canicola serogroup. The results of a survey on 12 dogs in the zone surrounding the Cimarron Channel suggest that they were the reservoir which contaminated the Channel waters. AD - Centro Provincial de Higiene y Epidemiologia de Ciego de Avila. PMID- 1812532 TT - Brote de leptospirosis en ninos con predomino meningoencefalico, en el municipio Moron. EA - A SO - Rev Cubana Med Trop 1991 Apr-Aug;43(2):136-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 91247168 AU - Woodward MJ AU - Sullivan GJ AU - Palmer NM AU - Woolley JC AU - Redstone JS TI - Development of a PCR test specific for Leptospira hardjo genotype bovis. LA - Eng MH - Animal MH - Base Sequence MH - Genotype MH - Leptospira/*isolation & purification MH - Molecular Sequence Data MH - Polymerase Chain Reaction/*veterinary MH - Species Specificity PT - JOURNAL ARTICLE DA - 910703 DP - 1991 Mar 23 IS - 0042-4900 TA - Vet Rec PG - 282-3 SB - M CY - ENGLAND IP - 12 VI - 128 JC - XBS EM - 9109 AD - Department of Bacteriology, Central Veterinary Laboratory, New Haw, Weybridge, Surrey. PMID- 2038811 SO - Vet Rec 1991 Mar 23;128(12):282-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 91286141 AU - Bates RO AU - Day BN AU - Britt JH AU - Clark LK AU - Brauer MA TI - Reproductive performance of sows treated with a combination of pregnant mare's serum gonadotropin and human chorionic gonadotropin at weaning in the summer. LA - Eng MH - Anestrus/drug effects MH - Animal MH - Estrus/drug effects MH - Female MH - Fertility/*drug effects MH - Gonadotropins, Chorionic/*pharmacology MH - Gonadotropins, Equine/*pharmacology MH - Leptospirosis/physiopathology/veterinary MH - Litter Size/drug effects MH - Parity MH - Random Allocation MH - Reproduction/*drug effects MH - Swine/*physiology MH - Swine Diseases/physiopathology MH - Weaning RN - 0 (Gonadotropins, Chorionic) RN - 0 (Gonadotropins, Equine) PT - JOURNAL ARTICLE DA - 910807 DP - 1991 Mar IS - 0021-8812 TA - J Anim Sci PG - 894-8 SB - M CY - UNITED STATES IP - 3 VI - 69 JC - HC7 AA - Author EM - 9110 AB - During the summer and fall of 1987, sows from eight herds in three states were assigned randomly to receive either a combination of 400 IU of pregnant mare's serum gonadotropin with 200 IU of hCG (P.G. 600) or no treatment at weaning. A treatment x parity interaction was observed for days to first estrus after treatment and percentage anestrus (percentage of sows not achieving estrus within 10 d after weaning). Relative to primiparous control sows, primiparous sows given P.G. 600 expressed estrus sooner (P less than .02) after weaning (6.0 vs 7.8 +/- .6 d) and exhibited less (P less than .02) postweaning anestrus (15.6 vs 29.2 +/- 4.0%). Second parity sows that received P.G. 600 showed estrus sooner (P less than .06) than second-parity control sows (4.7 vs 6.4 +/- .7 d). Days to first estrus after treatment did not differ between groups for parity-three and older sows, and percentage anestrus was not different between treatments for parity-two and older sows. The herd X treatment interaction was significant for percentage recycled (percentage of successfully mated sows that returned to estrus), subsequent farrowing rate, and subsequent number of pigs born dead. Number of pigs born alive was lower for sows treated with P.G. 600 than for control sows (10.55 vs 10.10 +/- .18; P less than .02). In summary, treatment of sows weaned in the summer and fall with P.G. 600 had decreased days to postweaning estrus in parity-one and -two sows and reduced frequency of postweaning anestrus in primiparous sows. AD - Dept. of Anim. Sci., Univ. of Missouri, Columbia 65211. PMID- 2061259 CU - 92 SO - J Anim Sci 1991 Mar;69(3):894-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 91268504 AU - Goldstein EJ TI - Household pets and human infections. LA - Eng MH - Animal MH - *Animals, Domestic MH - Brucellosis/transmission MH - Cat-Scratch Disease/transmission MH - Diarrhea/etiology MH - Human MH - Leptospirosis/transmission MH - Mycobacterium Infections/transmission MH - Mycoses/transmission MH - Ornithosis/transmission MH - Parasitic Diseases/transmission MH - Streptococcal Infections/transmission MH - Zoonoses/*transmission PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 910725 DP - 1991 Mar IS - 0891-5520 TA - Infect Dis Clin North Am PG - 117-30 SB - M CY - UNITED STATES IP - 1 VI - 5 JC - IDC AA - Author EM - 9109 AB - Because many Americans keep a wide variety of household pets, they are exposed to the many pet-associated diseases that are transmitted in various ways, including through bites, scratches, saliva, excreta, and respiration. This article briefly describes a number of the illnesses that may be acquired from household pets. AD - University of California, School of Medicine, Los Angeles. RF - 39 PMID- 2051011 SO - Infect Dis Clin North Am 1991 Mar;5(1):117-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 91257387 AU - Anan'ina IuV TI - [Leptospirosis] LA - Rus MH - Agricultural Workers' Diseases/diagnosis/etiology/parasitology MH - Animal MH - Animals, Domestic MH - Animals, Wild MH - Disease Vectors MH - Human MH - Leptospirosis/diagnosis/parasitology/*transmission MH - Weil's Disease/diagnosis/parasitology/*transmission PT - JOURNAL ARTICLE DA - 910718 DP - 1991 Mar IS - 0014-9772 TA - Feldsher Akush PG - 3-8 SB - N CY - USSR IP - 3 VI - 56 JC - EVA EM - 9109 PMID- 2044817 LI - N TT - Leptospirozy. SO - Feldsher Akush 1991 Mar;56(3):3-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 91252662 AU - Friedland JS AU - Warrell DA TI - The Jarisch-Herxheimer reaction in leptospirosis: possible pathogenesis and review [see comments] LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*complications/drug therapy MH - Male MH - Middle Age MH - Penicillins/*therapeutic use MH - Shock, Septic/*etiology/physiopathology MH - Tumor Necrosis Factor/physiology RN - 0 (Penicillins) RN - 0 (Tumor Necrosis Factor) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW OF REPORTED CASES DA - 910708 DP - 1991 Mar-Apr IS - 0162-0886 TA - Rev Infect Dis PG - 207-10 SB - M CY - UNITED STATES IP - 2 VI - 13 JC - SXN AA - Author EM - 9109 AB - The importance of treating leptospirosis with penicillin is emphasized by two case reports and a review documenting the occurrence of the Jarisch-Herxheimer reaction (JHR) in patients with this bacterial infection. The JHR is significant both as a cause of morbidity and mortality and as an indication of the therapeutic efficacy of penicillin. The possible etiology of the JHR is discussed, and comparisons with the changes occurring in septic shock are made; a study of either condition facilitates the understanding of the other. Tumor necrosis factor is hypothesized to play a key role in both. Current treatment of the JHR consists of general clinical support. Specific measures such as oxpentifylline therapy may play a role in the future. AD - Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford, United Kingdom. RF - 44 CM - Comment in: Rev Infect Dis 1991 Nov-Dec;13(6):1245-6 RO - M:LC1 PMID- 2041950 LR - 920609 CU - 92 SO - Rev Infect Dis 1991 Mar-Apr;13(2):207-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 91240034 AU - Scanziani E AU - Luini M AU - Fabbi M AU - Pizzocaro P TI - Comparison between specific immunoperoxidase staining and bacteriological culture in the diagnosis of renal leptospirosis of pigs. LA - Eng MH - Animal MH - Bacteriological Techniques/*veterinary MH - Comparative Study MH - Immunoenzyme Techniques/*veterinary MH - Kidney Diseases/diagnosis/*veterinary MH - Leptospirosis/diagnosis/*veterinary MH - Predictive Value of Tests MH - Sensitivity and Specificity MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 910624 DP - 1991 Mar IS - 0034-5288 TA - Res Vet Sci PG - 229-32 SB - M CY - ENGLAND IP - 2 VI - 50 JC - R7D AA - Author EM - 9108 AB - Seventy-two pigs were examined for the presence of leptospires in the kidney by both bacteriological culture and an immunoperoxidase procedure performed on formalin-fixed, paraffin-embedded sections of tissue with a primary antibody raised in rabbits against serovar pomona. The methods were in accordance in 62 of 70 (89 per cent) of the specimens. Compared with culture the sensitivity of the immunoperoxidase procedure was 30 of 38 (78 per cent) and its specificity 100 per cent; the predictive value of a positive result was 100 per cent, of a negative result, 80 per cent. The major advantages of the immunoperoxidase procedure are specificity, speed of execution and the possibility of simultaneous visualisation of leptospiral antigen and microscopic lesion. AD - Istituto di Anatomia Patologica Veterinaria e Patologia Aviare, Facolta di Medicina Veterinaria, Milan, Italy. PMID- 2034904 SO - Res Vet Sci 1991 Mar;50(2):229-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 91228374 AU - Dixon AC TI - The cardiovascular manifestations of leptospirosis. LA - Eng MH - Adult MH - Cardiovascular Diseases/*etiology MH - Case Report MH - Electrocardiography MH - Human MH - Leptospirosis/*complications MH - Male PT - JOURNAL ARTICLE DA - 910612 DP - 1991 Mar IS - 0093-0415 TA - West J Med PG - 331-4 SB - A SB - M CY - UNITED STATES IP - 3 VI - 154 JC - XN5 EM - 9108 AD - Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu. PMID- 2028604 SO - West J Med 1991 Mar;154(3):331-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 91147193 AU - Haake DA AU - Walker EM AU - Blanco DR AU - Bolin CA AU - Miller MN AU - Lovett MA TI - Changes in the surface of Leptospira interrogans serovar grippotyphosa during in vitro cultivation. LA - Eng MH - Animal MH - Antibodies, Bacterial/immunology MH - Antigens, Surface/*analysis/immunology MH - Bacterial Outer Membrane Proteins/*analysis/immunology/ultrastructure MH - Electrophoresis, Polyacrylamide Gel MH - Freeze Fracturing MH - Hamsters MH - Leptospira interrogans/analysis/immunology/*pathogenicity/ultrastructure MH - Molecular Weight MH - Polyethylene Glycols MH - Polysaccharides, Bacterial/*analysis/immunology MH - Precipitin Tests MH - Rabbits MH - Serial Passage MH - Solubility MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Virulence RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Surface) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Polyethylene Glycols) RN - 0 (Polysaccharides, Bacterial) RN - 9036-19-5 (Nonidet P-40) PT - JOURNAL ARTICLE ID - AI 21352/AI/NIAID ID - AI 29733/AI/NIAID ID - AI 12601/AI/NIAID DA - 910402 DP - 1991 Mar IS - 0019-9567 TA - Infect Immun PG - 1131-40 SB - M SB - X CY - UNITED STATES IP - 3 VI - 59 JC - GO7 AA - Author EM - 9106 AB - Surface components of virulent and attenuated Leptospira interrogans serovar grippotyphosa were compared by using Triton X-114 solubilization and phase partitioning, immunoprecipitation of intact organisms, and freeze-fracture electron microscopy. Removal of the leptospiral outer membrane by using 0.1% Triton X-114 was demonstrated by whole-mount electron microscopy and by essentially complete solubilization of a lipopolysaccharidelike substance (LLS) from the outer membrane. Triton X-114 (0.1%) did not solubilize subsurface proteins, such as endoflagellar filaments or penicillin-binding proteins, which are markers for the periplasmic space and inner membrane, respectively. Triton X-114 solubilized material from both the virulent and attenuated strains, which partitioned into the hydrophobic, detergent phase, contained LLS and major proteins of 41 and 44 kDa, which were also immunoprecipitable from intact organisms. The virulent strain contained greater amounts of an LLS component with an apparent molecular mass of 30 kDa (R(f) = 0.57), whereas the attenuated strain contained larger amounts of an LLS component with an apparent molecular mass of 20 kDa (R(f) = 0.74). Differences in protein components between virulent and attenuated organisms were also detected; whereas the 41- and 44-kDa proteins were immunoprecipitated in equal amounts from both the virulent and attenuated strains, a 33- kDa protein was immunoprecipitated in significantly greater amounts from the attenuated strain. Quantitation of outer membrane particle density by freeze-fracture electron microscopy showed that both strains had a low transmembrane outer membrane protein content compared with that of typical gram-negative bacteria. The virulent and attenuated strains had 443 and 990 particles (P less than 0.000001) per micron, respectively, in the concave outer membrane fracture face. These findings suggest that in vitro cultivation of L. interrogans is accompanied by quantitative and qualitative changes in both LLS and outer membrane-associated proteins. AD - Department of Medicine, UCLA School of Medicine 90024. PMID- 1997416 CU - 92 SO - Infect Immun 1991 Mar;59(3):1131-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 91361411 AU - Venkataraman KS AU - Ramkrishna J AU - Raghavan N TI - Human leptospirosis: a recent study in Madras, India. LA - Eng MH - Antibodies, Bacterial/analysis MH - Human MH - India/epidemiology MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/epidemiology MH - Seroepidemiologic Methods RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 911007 DP - 1991 Mar-Apr IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 304 SB - M CY - ENGLAND IP - 2 VI - 85 JC - WBU EM - 9112 AD - Department of Preventive Medicine, Madras Veterinary College, India. PMID- 1887496 CU - 91 SO - Trans R Soc Trop Med Hyg 1991 Mar-Apr;85(2):304 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 91228678 AU - Robinson CR TI - Oil immersion for identification of Campylobacter pylori [letter; comment] LA - Eng MH - Bacteriological Techniques MH - Campylobacter/*isolation & purification MH - Campylobacter Infections/*diagnosis/pathology MH - Human MH - Leptospira/isolation & purification MH - Stomach/microbiology/pathology PT - COMMENT PT - LETTER DA - 910611 DP - 1991 Mar-Apr IS - 0001-5547 TA - Acta Cytol PG - 252-3 SB - M SB - X CY - UNITED STATES IP - 2 VI - 35 JC - 0LI EM - 9108 CM - Comment on: Acta Cytol 1990 Mar-Apr;34(2):205-10 CM - Comment on: Acta Cytol 1990 Mar-Apr;34(2):211-3 RO - M:CNR PMID- 1824230 LR - 921013 SO - Acta Cytol 1991 Mar-Apr;35(2):252-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 92128864 AU - Ye D AU - Yan R AU - Li S AU - Peng H AU - Xu X TI - [The production of human monoclonal antibodies against Pseudomonas aeruginosa by human-mouse hybridoma technique] LA - Chi MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Antibodies, Monoclonal/*biosynthesis MH - English Abstract MH - Female MH - Human MH - Hybridomas/secretion MH - IgG/biosynthesis MH - Mice MH - Mice, Inbred BALB C MH - Pseudomonas aeruginosa/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 920228 DP - 1991 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 24-6 CY - CHINA IP - 1 VI - 22 JC - GEB AA - Author EM - 9205 AB - The fusion of peripheral B lymphocytes from human immunized with P. aeruginosa polyvalent vaccine and mouse myeloma cell line SP2/0 was successfully performed. The rate of fusion was 74%(71/96) and the positive rate of antibody was 19.7%. Two hybridoma cell lines (A3 and F8) secreting McAb against P. aeruginosa were obtained after three times cloning by limiting dilution. The human chromosomes together with mouse chromosomes were discovered in karyotype assay of the hybrids. A3 and F8McAbs were human IgG by class determination. These MrcAbs could recognize 43 kd and 36 kd MW specific components of P. aeruginosa antigen by enzyme linked immuno-transfer blot technique. AD - Research Unit of Leptospirosis. PMID- 1774030 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1991 Mar;22(1):24-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 91244968 AU - Ito F AU - Hunter EF AU - George RW AU - Swisher BL AU - Larsen SA TI - Specific immunofluorescence staining of Treponema pallidum in smears and tissues. LA - Eng MH - Animal MH - Antibodies, Bacterial MH - Bacteriological Techniques MH - Evaluation Studies MH - *Fluorescent Antibody Technique MH - Human MH - Male MH - Rabbits MH - Staining MH - Syphilis/*diagnosis MH - Treponema pallidum/immunology/*isolation & purification RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910628 DP - 1991 Mar IS - 0095-1137 TA - J Clin Microbiol PG - 444-8 SB - M CY - UNITED STATES IP - 3 VI - 29 JC - HSH AA - Author EM - 9109 AB - To date, tissue sections prepared from Formalin-fixed tissues have not been successfully stained with Treponema pallidum subspecies-specific antibody in a direct fluorescent-antibody assay. While current methods stain T. pallidum, they do not distinguish T. pallidum from other spirochetes such as Borrelia burgdorferi (E. F. Hunter, P. W. Greer, B. L. Swisher, A. R. Simons, C. E. Farshy, J. A. Crawford, and K. R. Sulzer, Arch. Pathol. Lab. Med. 108:878-880, 1984). Because trypsin pretreatment of tissue sections has enhanced other immunofluorescent- antibody (IFA) applications, we compared the use of the trypsin digestion method with the current 1% ammonium hydroxide (NH4OH) method as a means to obtain specific staining of T. pallidum in tissues by both direct and indirect IFA techniques. Pretreated T. pallidum- infected tissues sections from rabbits, hamsters, and humans were quantitatively examined with the direct fluorescent-antibody-T. pallidum test conjugate absorbed with Treponema phagedenis, the Reiter treponeme. For indirect staining, a serum specimen from a patients with syphilis absorbed by affinity chromatography with T. phagedenis was used as the primary reagent, and a fluorescein isothiocyanate-labeled rabbit anti-human globulin was used as the secondary reagent. Serum specificity was established first by examining antigen smears of T. pallidum subsp. pallidum, T. pallidum subsp. pertenue, B. burgdorferi, T. phagedenis, and Treponema denticola MRB and then by examining tissues infected with these pathogens plus those infected with four Leptospira serovars. When we stained tissue using the direct IFA method that is currently a standard method for the examination of chancre smears, we found it to be unsuitable for use with tissue.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Dermatology, Second Hospital of Nippon Medical School, Kanagawa, Japan. PMID- 1709944 CU - 95 SO - J Clin Microbiol 1991 Mar;29(3):444-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 91167813 TI - Leptospirosis update [letter; comment] LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Occupational Diseases/epidemiology MH - Scotland/epidemiology PT - COMMENT PT - LETTER DA - 910424 DP - 1991 Feb 23 IS - 0959-8138 TA - BMJ PG - 471-2 SB - A SB - M SB - X CY - ENGLAND IP - 6774 VI - 302 JC - BMJ EM - 9106 CM - Comment on: BMJ 1991 Jan 19;302(6769):128-9 RO - M:LC2 PMID- 2004184 LR - 910722 NI - A SO - BMJ 1991 Feb 23;302(6774):471-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 91180934 AU - de Waal CA AU - Hartman EG AU - Bokhout BA AU - van Leengoed LA TI - [Leptospirosis in swine; observations on the serological diagnosis of Leptospira interrogans serotype bratislava (published erratum appears in Tijdschr Diergeneeskd 1991 Mar 1;116(5):228)] LA - Dut MH - Animal MH - English Abstract MH - Leptospira interrogans/*immunology MH - Reproduction MH - Serotyping/veterinary MH - Swine/physiology MH - Swine Diseases/*immunology MH - Weil's Disease/immunology/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 910502 DP - 1991 Feb 15 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 173-9 SB - M CY - NETHERLANDS IP - 4 VI - 116 JC - VRY AA - Author EM - 9107 AB - Leptospirosis is considered to be an important cause of porcine reproductive failure. In this respect recently attention is paid to the possible role of Leptospira interrogans serotype bratislava (bratislava). In the present paper the results of serotype bratislava serology conducted on three farms are presented and discussed. On two of the farms no reproductive failure was observed. On the third farm with a high percentage of return to service a longitudinal search was done. No relation could be demonstrated between bratislava titers and reproductive failure. AD - Gezondheidsdienst voor Dieren in Gelderland, Velp. RO - M:MWS PMID- 2008705 LR - 910530 TT - Leptospirose bij het varken; kanttekeningen bij de serologische diagnostiek van Leptospira interrogans serotype bratislava. EA - A SO - Tijdschr Diergeneeskd 1991 Feb 15;116(4):173-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 91238270 TI - [Leptospirosis: a problem of diagnosis (letter)] LA - Spa MH - Human MH - Leptospirosis/*diagnosis MH - Methods PT - LETTER DA - 910627 DP - 1991 Feb 9 IS - 0025-7753 TA - Med Clin (Barc) PG - 194-5 CY - SPAIN IP - 5 VI - 96 JC - LTQ EM - 9108 PMID- 2033993 NI - A TT - Leptospirosis: un problema de diagnostico. SO - Med Clin (Barc) 1991 Feb 9;96(5):194-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 91130549 AU - Bennett S AU - Everard CO TI - Absence of epidemicity of severe leptospirosis in Barbados. LA - Eng MH - Barbados/epidemiology MH - Cluster Analysis MH - *Disease Outbreaks MH - Human MH - Leptospirosis/*epidemiology MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 910315 DP - 1991 Feb IS - 0950-2688 TA - Epidemiol Infect PG - 151-6 SB - M CY - ENGLAND IP - 1 VI - 106 JC - EPI AA - Author EM - 9105 AB - The possibility of micro-epidemics of severe leptospirosis occurring on the island of Barbados was investigated by examining the space-time clustering of the disease in 212 laboratory-confirmed cases admitted to Queen Elizabeth Hospital, Bridgetown, over a 7-year period. A series of 109 patients with symptoms compatible with leptospirosis but shown to be otherwise by laboratory examination were also examined for comparison. No significant space-time clustering was found among the leptospirosis cases, indicating no evidence for micro-epidemics. By comparison, statistically significant clustering was apparent among the smaller non-leptospirosis series. Possible explanations for the absence of observed micro-epidemics of leptospirosis are discussed. AD - Tropical Health Epidemiology Unit, London School of Hygiene and Tropical Medicine, UK. PMID- 1993448 SO - Epidemiol Infect 1991 Feb;106(1):151-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 91229926 TI - Communicable disease report. July to September 1990. From the PHLS Communicable Disease Surveillance Centre. LA - Eng MH - Animal MH - Cats MH - Cowpox/transmission MH - Cryptosporidiosis/epidemiology/*transmission MH - Great Britain/epidemiology MH - Hepatitis A/epidemiology MH - Hepatitis B/epidemiology MH - Hepatitis C/epidemiology MH - Hepatitis, Viral, Human/*epidemiology MH - Human MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 910620 DP - 1991 Feb IS - 0957-4832 TA - J Public Health Med PG - 48-53 SB - M CY - ENGLAND IP - 1 VI - 13 JC - AP2 EM - 9108 PMID- 1903041 CU - 91 NI - A SO - J Public Health Med 1991 Feb;13(1):48-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 91347355 AU - Zhang HY TI - [The specificity of plague antigen FI in PHA] LA - Chi MH - Animal MH - Antigens, Bacterial/*immunology MH - Cross Reactions MH - English Abstract MH - Hemagglutination Tests/*methods MH - Leptospira/immunology MH - Mice MH - Muridae/microbiology MH - Yersinia pestis/*immunology RN - 0 (antigen V (Yersinia pestis)) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 911003 DP - 1991 Feb IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 36-9 CY - CHINA IP - 1 VI - 12 JC - CQG AA - Author EM - 9112 AB - It were inoculate a total of the 15 type and 13 group Leptospira strains to the Rattus flavipetus and Rattus lose 137 rates in Lei Zhou peninsula. As the antisera acquired, it has been examined the lyso- agglutinative test in Leptospira strains. Up to standard serum it was to test for PHA of plaque, employing the sensitized blood cell by FI from 4 antiplague institutes. All of tests are negative. In addition to test for 3 immune sera, Hemorrhagic Fever antisera (Immunized animals Apodemus agraius, Rattus norvegicus, Mouse and Rabbit), anthrax antiserum, there were be negative by PHA of plague test, at same time by RIA test also be negative. Therefore all of the other antisera would not be interfering with specificity of the plague FI antiserum in PHA or RIA test. AD - Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing. PMID- 1878960 CU - 91 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1991 Feb;12(1):36-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 91347348 AU - Pan LN TI - [The discover of Lyme disease in Fujian Province] LA - Chi MH - Adult MH - Animal MH - Arachnid Vectors MH - Borrelia burgdorferi/isolation & purification MH - China/epidemiology MH - English Abstract MH - Fluorescent Antibody Technique MH - Human MH - Lyme Disease/*epidemiology MH - Male MH - Middle Age MH - Mites/microbiology MH - Prevalence MH - Seroepidemiologic Methods PT - JOURNAL ARTICLE DA - 911003 DP - 1991 Feb IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 1-4 CY - CHINA IP - 1 VI - 12 JC - CQG AA - Author EM - 9112 AB - By means of indirect fluorescent antibody assay (IFA), Borrelia burgdorferi B31 strain was used for antigen, to detect the 2579 serum specimens from forest area in 9 counties of Fujian province, 47 cases in 8 counties were detected positive, positive rate was 1.82%. By epidemiological investigation, we found that peoples who infected with Lyme disease, 91.67% of them (22/24) have been bited by Ixodes, and 6 cases suffer typical clinical symptoms of Lyme disease, 9 cases have the similar or somewhat typical symptoms. We found Lyme disease could be cross-reaction to leptospirosis, in this paper the serum specimens which Lyme disease and leptospirosis all positive, we were not consider them to Lyme disease for time being, no matter the patients may be have suffer double infection. The indentification of the cross-reaction between Lyme disease and leptospirosis should be further studied. AD - Fujian Provincial Center of Sanitary and Epidemic Prevention, Fuzhou. PMID- 1878953 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1991 Feb;12(1):1-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 91327879 AU - Agaev IA TI - [The mechanisms maintaining epidemic foci of leptospirosis] LA - Rus MH - Age Factors MH - Agricultural Workers' Diseases/epidemiology/etiology MH - Animal MH - Azerbaijan/epidemiology MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Outbreaks/*statistics & numerical data MH - Disease Reservoirs/*statistics & numerical data MH - English Abstract MH - Human MH - *Leptospira canicola MH - Leptospirosis/*epidemiology/etiology/veterinary MH - Prevalence MH - Rural Population/statistics & numerical data MH - Weil's Disease/*epidemiology/etiology/veterinary PT - JOURNAL ARTICLE DA - 910911 DP - 1991 Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 38-41 SB - M CY - USSR IP - 2 JC - Y9O AA - Author EM - 9111 AB - 24,419 samples of blood serum, collected in the Azerbaijan SSR among different professional groups of the population, have been tested for leptospirosis. The comparison of the results with those obtained in the natural foci of leptospirosis and in the foci of this infection appearing as a consequence of human activities has made it possible to come to the conclusion that the epidemic foci of leptospirosis are maintained due to the existence of foci among cattle. The cases of contamination among persons professionally linked with large cattle breeding complexes have been found to exceed those among persons working at farms of a nonindustrial type. PMID- 1830996 CU - 92 TT - Mekhanizmy podderzhaniia epidemicheskikh ochagov leptospirozov. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1991 Feb;(2):38-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 92141520 AU - Perez-Requena J AU - Fernandez-Barrios A AU - Baena R AU - Gomez-Fernandez P TI - [Acute renal failure in leptospirosis. Presentation of 2 cases (letter)] LA - Spa MH - Adult MH - Case Report MH - Human MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications MH - Male MH - Middle Age PT - LETTER DA - 920306 DP - 1991 Feb IS - 0014-2565 TA - Rev Clin Esp PG - 163-5 CY - SPAIN IP - 3 VI - 188 JC - RNL EM - 9205 PMID- 1780518 TT - Fracaso renal agudo en leptospirosis. Presentacion de dos casos. SO - Rev Clin Esp 1991 Feb;188(3):163-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 91283231 AU - Cinco M AU - Banfi E AU - Balanzin D AU - Godeas C AU - Panfili E TI - Evidence for (lipo) oligosaccharides in Borrelia burgdorferi and their serological specificity. LA - Eng MH - Animal MH - Antibody Specificity MH - Antigens, Bacterial/*immunology MH - Bacterial Outer Membrane Proteins/immunology MH - Blotting, Western MH - Borrelia burgdorferi/*immunology MH - Borrelia Infections/immunology MH - Electrophoresis, Polyacrylamide Gel MH - Epitopes MH - Flagellin/immunology MH - Human MH - Leptospirosis/immunology MH - Lipopolysaccharides/*immunology MH - Lyme Disease/immunology MH - Rabbits MH - Serine Proteinases/metabolism MH - Serotyping MH - Syphilis/immunology RN - EC 3.4.21 (Serine Proteinases) RN - EC 3.4.21.64 (Endopeptidase K) RN - 0 (lipid-linked oligosaccharides) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Epitopes) RN - 0 (Lipopolysaccharides) RN - 12777-81-0 (Flagellin) PT - JOURNAL ARTICLE DA - 910807 DP - 1991 Feb IS - 0920-8534 TA - FEMS Microbiol Immunol PG - 33-8 SB - M CY - NETHERLANDS IP - 1 VI - 3 JC - AO3 AA - Author EM - 9110 AB - SDS-PAGE and Western immunoblot profiles have been determined for different strains of Borrelia burgdorferi. Major proteins of 60 kDa, 41 kDa corresponding to flagellin, 34-36 kDa and 30-31 kDa corresponding to OspB and OspA respectively, and 18-20 kDa corresponding to 'pC' fractions were detected. A "rough" lipopolysaccharide which we called lipooligosaccharide (LOS) of 8-11 kDa appeared to be present, being detected by specific silver staining, as in crude Borrelia lysates as in proteinase K digested Borrelia strains, quite similar in shape among the different strains examined. The LOS reacted in Western blotting with immune anti-B. burgdorferi rabbit serum and also with sera collected from humans affected by Lyme borreliosis. The LOS did not react with sera positive for syphilis or leptospirosis, and their immunological specificity is discussed. AD - Istituto di Microbiologia, Universita degli Studi, Trieste, Italy. PMID- 1711876 CU - 96 SO - FEMS Microbiol Immunol 1991 Feb;3(1):33-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 91137919 AU - Ferguson IR TI - Leptospirosis update [editorial] [see comments] LA - Eng MH - Animal MH - Antibiotics/therapeutic use MH - Human MH - Leptospirosis/*prevention & control MH - Occupational Diseases/prevention & control MH - Rats MH - Risk Factors MH - Vaccination RN - 0 (Antibiotics) PT - EDITORIAL DA - 910325 DP - 1991 Jan 19 IS - 0959-8138 TA - BMJ PG - 128-9 SB - A SB - M SB - X CY - ENGLAND IP - 6769 VI - 302 JC - BMJ EM - 9105 CM - Comment in: BMJ 1991 Feb 23;302(6774):471-2 RO - M:LC2 PMID- 2053935 LR - 910722 CU - 91 SO - BMJ 1991 Jan 19;302(6769):128-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 91205716 AU - Power SB TI - Diagnosing Leptospira in pigs [letter] LA - Eng MH - Abortion, Veterinary/*diagnosis MH - Animal MH - Female MH - Fetal Death/diagnosis/*veterinary MH - Genital Diseases, Female/diagnosis/*veterinary MH - Leptospirosis/diagnosis/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*diagnosis PT - LETTER DA - 910523 DP - 1991 Jan 12 IS - 0042-4900 TA - Vet Rec PG - 43 SB - M CY - ENGLAND IP - 2 VI - 128 JC - XBS EM - 9107 PMID- 2017847 SO - Vet Rec 1991 Jan 12;128(2):43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 91284172 AU - Ezeh AO AU - Adesiyun AA AU - Addo PB AU - Ellis WA AU - Makinde AA AU - Bello CS TI - Serological and cultural examination for human leptospirosis in Plateau State, Nigeria. LA - Eng MH - Abattoirs MH - Agriculture MH - Human MH - Leptospirosis/blood/*epidemiology/microbiology MH - Nigeria/epidemiology MH - Occupational Diseases/blood/*epidemiology/microbiology MH - Personnel, Hospital MH - Prevalence MH - Risk Factors MH - Seroepidemiologic Methods MH - Serotyping PT - JOURNAL ARTICLE DA - 910802 DP - 1991 Jan IS - 0008-9176 TA - Cent Afr J Med PG - 11-5 CY - ZIMBABWE IP - 1 VI - 37 JC - CQO AA - Author EM - 9110 AB - In a serological examination of 710 serum samples collected from human volunteers in Plateau State, Nigeria, 128 (18.0pc) had leptospiral antibody titres of 1:100 and above. The prevalence of antibodies to individual serovars were: hardjo 28 (21.9pc), pomona 18 (14.1pc), canicola 17 (13.3pc), grippotyphosa 15 (11.7pc), pyrogenes 13 (10.2pc), icterohaemorrhagiae 12 (0.4pc) and autumnalis 8 (6.3pc). There was no statistical difference in the prevalence rate of leptospirosis in the different local government areas (p greater than 0.05; X2). Among the occupational groups examined, the abattoir workers were particularly at risk with a prevalence rate of 29.5pc. A leptospiral variant of strain Hardjoprajitno was also isolated from the midstream urine of an abattoir worker who was apparently healthy. The isolation of Leptospira interrogans serovar hardjo in man is the first such report in Nigeria. AD - National Veterinary Research Institute, Vom, Nigeria. PMID- 2060002 SO - Cent Afr J Med 1991 Jan;37(1):11-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 91280461 AU - Blazhniaia LP AU - Mel'nik GV AU - Arapov IuP TI - [Early diagnosis of leptospirosis] LA - Rus MH - Adult MH - Comparative Study MH - Female MH - Human MH - Leptospira interrogans MH - Male MH - Methods MH - Time Factors MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 910801 DP - 1991 IS - 0038-5077 TA - Sov Med PG - 78-80 CY - USSR IP - 2 JC - UW7 EM - 9110 PMID- 2057852 TT - O rannei diagnostike leptospiroza. SO - Sov Med 1991;(2):78-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 protein link] [1 nucleotide link] [205 medline neighbors] UI - 91241769 AU - Stamm LV AU - Parrish EA AU - Gherardini FC TI - Cloning of the recA gene from a free-living leptospire and distribution of RecA-like protein among spirochetes. LA - Eng MH - Cloning, Molecular MH - *Genes, Bacterial MH - Genetic Complementation Test MH - Leptospira/*genetics/metabolism MH - Plasmids MH - Rec A Protein/*genetics/metabolism MH - Recombination, Genetic MH - Spirochaetales/genetics/metabolism MH - Support, U.S. Gov't, P.H.S. MH - Virus Activation RN - 0 (Plasmids) RN - 0 (Rec A Protein) PT - JOURNAL ARTICLE ID - AI15036/AI/NIAID ID - AI24976/AI/NIAID ID - AI07953/AI/NIAID DA - 910624 DP - 1991 Jan IS - 0099-2240 TA - Appl Environ Microbiol PG - 183-9 SB - M CY - UNITED STATES IP - 1 VI - 57 JC - 6K6 AA - Author EM - 9108 AB - A recombinant plasmid carrying the recA gene of Leptospira biflexa serovar patoc was isolated from a cosmid library of genomic DNA by complementation of an Escherichia coli recA mutation. The cloned serovar patoc recA gene efficiently restored resistance to UV radiation and methyl methanesulfonate. Recombination proficiency was also restored, as measured by the formation of Lac+ recombinants from duplicated mutant lacZ genes. Additionally, the cloned recA gene increased the spontaneous and mitomycin C-induced production of lambda phage in lysogens of an E. coli recA mutant. The product of the cloned recA gene was identified in maxicells as a polypeptide with an Mr of 43,000. Antibodies prepared against the E. coli RecA protein cross- reacted with the serovar patoc RecA protein, indicating structural conservation. Southern hybridization data showed that the serovar patoc recA gene has diverged from the recA gene of L. interrogans, Leptonema illini, and E. coli. With the exception of the RecA protein of L. interrogans serovar hardjo, the RecA protein of the Leptospira serovars and L. illini were synthesized at elevated levels following treatment of cells with nalidixic acid. The level of detectable RecA correlated with previous studies demonstrating that free-living cells of L. biflexa serovars and L. illini were considerably more resistant to DNA- damaging agents than were those of parasitic L. interrogans serovars. RecA protein was not detected in cells of virulent Treponema pallidum or Borrelia burgdorferi. AD - Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599-7400. PMID- 2036006 CU - 92 GS - recA SO - Appl Environ Microbiol 1991 Jan;57(1):183-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 91223106 AU - Yukawa M TI - Differential susceptibility of two stocks of Mongolian gerbils (Meriones unguiculatus) to Leptospira. LA - Eng MH - Animal MH - Disease Susceptibility MH - Female MH - *Gerbillinae MH - Male MH - Rodent Diseases/*immunology MH - Weil's Disease/immunology/*veterinary PT - JOURNAL ARTICLE DA - 910607 DP - 1991 IS - 0939-8600 TA - J Exp Anim Sci PG - 1-5 CY - GERMANY IP - 1 VI - 34 JC - A09 AA - Author EM - 9108 AB - Mongolian gerbils (Meriones unguiculatus) of Tumble Blook (TUM) and Japan Medical Science (JMS) stocks were compared with regard to susceptibility to Leptospira interrogans serovar copenhageni. The TUM gerbil died 6 to 9 d after intraperitoneal inoculation with 10 organisms, showing jaundice and systemic hemorrhage. However, 25% of the JMS gerbils survived infection with 10(3) or 10(4) organisms and there was no fatal case after infection with 10(2) organisms. AD - Laboratory of Biomedical Science, Nihon University, Veterinary School, Japan. PMID- 2025654 SO - J Exp Anim Sci 1991;34(1):1-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 91220609 AU - Goddard RD AU - Luff PR AU - Thornton DH TI - The serological response of calves to Leptospira interrogans serovar hardjo vaccines and infection as measured by the microscopic agglutination test and anti-IgM and anti-IgG enzyme-linked immunosorbent assay. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Bacterial Vaccines/*immunology MH - Cattle MH - Cattle Diseases/*immunology MH - Enzyme-Linked Immunosorbent Assay MH - IgG/biosynthesis MH - IgM/biosynthesis MH - Leptospira interrogans/*immunology MH - Reproducibility of Results MH - Vaccination/veterinary MH - Vaccines, Inactivated/immunology MH - Weil's Disease/immunology/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (Vaccines, Inactivated) PT - JOURNAL ARTICLE DA - 910604 DP - 1991 Jan IS - 0378-1135 TA - Vet Microbiol PG - 191-201 SB - M CY - NETHERLANDS IP - 1-2 VI - 26 JC - XBW AA - Author EM - 9108 AB - The microscopic agglutination test (MAT) and the anti-IgM and anti-IgG enzyme-linked immunosorbent assays (ELISA) were used to examine sera taken over the course of 16 weeks from 35 calves vaccinated and/or infected with Leptospira interrogans serovar hardjo. The relationship between the IgM and IgG responses to vaccination and infection were determined. The rapid and high rise in IgM levels following challenge made the anti-IgM ELISA a potentially good indicator of recently established infection although some transitory high levels were seen where infection did not become established. The slow IgG response to infection made the anti-IgG ELISA of limited diagnostic use. AD - Central Veterinary Laboratory, Weybridge, Surrey, UK. PMID- 2024440 CU - 92 SO - Vet Microbiol 1991 Jan;26(1-2):191-201 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 91218245 AU - Kita J AU - Anusz K TI - Serologic survey for bovine pathogens in free-ranging European bison from Poland. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/blood MH - Antibodies, Viral/blood MH - Bison/*microbiology MH - Cattle MH - Cattle Diseases/*epidemiology/microbiology/transmission MH - Female MH - Immunologic Techniques MH - Male MH - Poland RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 910603 DP - 1991 Jan IS - 0090-3558 TA - J Wildl Dis PG - 16-20 SB - M CY - UNITED STATES IP - 1 VI - 27 JC - KEM AA - Author EM - 9108 AB - From 1980 to 1983, blood was taken from 60 selected European bison (Bison bonasus) in Poland. Serum samples were tested for the presence of antibodies against Brucella abortus, 14 serovars of Leptospira interrogans, Chlamydia spp., Coxiella burnetti; foot and and mouth disease virus, bovine leukemia virus and bovine herpes virus-1. In addition, an attempt was made to isolate bovine herpes virus-1 from the prepuce of selected bulls. Serological tests suggested chlamydial infection in 28 bison, subclinical Q-fever of a 2-yr-old heifer, subclinical bovine leukemia virus infection in a 12-yr-old bull and bovine herpes virus-1 infection in five bulls and three cows. Attempts to isolate bovine herpes virus-1 were not successful. These results suggest the possibility of cross transmission of several of these bovine pathogens between free-ranging bison and domestic cattle in Poland. AD - Department of Infectious Diseases, Faculty of Veterinary Medicine, Warsaw Agricultural University, Poland. PMID- 2023316 CU - 91 SO - J Wildl Dis 1991 Jan;27(1):16-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 91188573 AU - Novikova RI AU - Shano VP AU - Logvinenko LV AU - Shramenko EK TI - [The treatment of leptospirosis complicated by severe liver-kidney failure] LA - Rus MH - Acute Disease MH - Adult MH - Case Report MH - Combined Modality Therapy/methods MH - English Abstract MH - Female MH - Human MH - Kidney Failure, Acute/etiology/*therapy MH - Liver Diseases/etiology/*therapy MH - Male MH - Middle Age MH - Weil's Disease/complications/*therapy PT - JOURNAL ARTICLE DA - 910509 DP - 1991 Jan IS - 0049-6804 TA - Vrach Delo PG - 81-4 CY - USSR IP - 1 JC - XLS AA - Author EM - 9107 AB - The authors examined 16 patients with severe forms of leptospirosis complicated by hepato-renal insufficiency. The treatment program included the following methods: hemodialysis, hemosorption, intraportal administration of drugs, gastrointestinal sorption via a heterospleen, hyperbaric oxygenation. As a result of this complex treatment lethality decreased by 15%. PMID- 2011904 TT - Lechenie leptospiroza, oslozhnennogo tiazheloi pechenochno-pochechnoi nedostatochnost'iu. EA - A SO - Vrach Delo 1991 Jan;(1):81-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 91130309 AU - Prescott J TI - Treatment of leptospirosis [editorial] LA - Eng MH - Acute Disease MH - Animal MH - Chronic Disease MH - Human MH - Leptospirosis/drug therapy/*veterinary MH - Weil's Disease/*drug therapy PT - EDITORIAL DA - 910318 DP - 1991 Jan IS - 0010-8901 TA - Cornell Vet PG - 7-12 SB - M CY - UNITED STATES IP - 1 VI - 81 JC - DRI EM - 9105 PMID- 1993395 SO - Cornell Vet 1991 Jan;81(1):7-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [9 protein links] [1 nucleotide link] [207 medline neighbors] UI - 91100341 AU - Brahamsha B AU - Han CY AU - Crawford IP AU - Greenberg EP TI - Nucleotide sequence and analysis of a gene encoding anthranilate synthase component I in Spirochaeta aurantia. LA - Eng MH - Amino Acid Sequence MH - Anthranilate Synthase/*genetics MH - Base Sequence MH - Chromosomes, Bacterial MH - Cloning, Molecular MH - Comparative Study MH - DNA, Bacterial/genetics MH - *Genes, Structural, Bacterial MH - Molecular Sequence Data MH - Nucleic Acid Hybridization MH - Plasmids MH - Repetitive Sequences, Nucleic Acid MH - Restriction Mapping MH - Sequence Homology, Nucleic Acid MH - Spirochaeta/enzymology/*genetics MH - Support, U.S. Gov't, Non-P.H.S. MH - Support, U.S. Gov't, P.H.S. RN - EC 4.1.3.27 (Anthranilate Synthase) RN - 0 (DNA, Bacterial) RN - 0 (Plasmids) PT - JOURNAL ARTICLE ID - AI 23275/AI/NIAID DA - 910220 DP - 1991 Jan IS - 0021-9193 TA - J Bacteriol PG - 541-8 SB - M CY - UNITED STATES IP - 2 VI - 173 JC - HH3 AA - Author EM - 9104 AB - A Spirochaeta aurantia DNA fragment containing the trpE gene and flanking chromosomal DNA was cloned, and the sequence of the trpE structural gene plus 870 bp upstream and 1,257 bp downstream of trpE was determined. The S. aurantia trpE gene codes for a polypeptide of 482 amino acid residues with a predicted molecular weight of 53,629 that showed sequence similarity to TrpE proteins from other organisms. The S. aurantia TrpE polypeptide is not more closely related to the other published spirochete TrpE sequence (that of Leptospira biflexa) than to TrpE polypeptides of other bacteria. Two additional complete open reading frames and one partial open reading frame were identified in the sequenced DNA. One of the complete open reading frames and the partial open reading frame are upstream of trpE and are encoded on the DNA strand opposite that containing trpE. The other open reading frame is downstream of trpE and on the same DNA strand as trpE. On the basis of the results of a protein sequence data base search, it appears that trpE is the only tryptophan biosynthesis gene in the sequenced DNA. This is in contrast to L. biflexa, in which trpE is separated from trpG by only 64 bp. AD - Department of Molecular Genetics and Cell Biology, University of Chicago, Illinois 60637. PMID- 1987149 CU - 92 GS - pabE GS - trpE GS - trpG SI - GENBANK/M55917 SI - GENBANK/S52645 SI - GENBANK/M60513 SI - GENBANK/S52985 SI - GENBANK/S52988 SI - GENBANK/S52991 SI - GENBANK/M64126 SI - GENBANK/M64127 SI - GENBANK/M64128 SI - GENBANK/M64129 SO - J Bacteriol 1991 Jan;173(2):541-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 91099981 AU - Taylor KA AU - Barbour AG AU - Thomas DD TI - Pulsed-field gel electrophoretic analysis of leptospiral DNA. LA - Eng MH - DNA, Bacterial/*analysis MH - Electrophoresis MH - Genes, Bacterial MH - Leptospira/*genetics/pathogenicity MH - Plasmids MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Virulence RN - 0 (DNA, Bacterial) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 910220 DP - 1991 Jan IS - 0019-9567 TA - Infect Immun PG - 323-9 SB - M SB - X CY - UNITED STATES IP - 1 VI - 59 JC - GO7 AA - Author EM - 9104 AB - The genomic structures of spirochete species are not well characterized, and genetic studies on these organisms have been hampered by lack of a genetic exchange mechanism in these bacteria. In view of these observations, pulsed-field gel electrophoresis was used to examine the genomes of Leptospira species. Live cells, prepared in agarose plugs, were lysed in situ, and the DNA was analyzed under different electrophoretic conditions. Pulsed-field gel electrophoresis of DNA digested with infrequently cutting restriction enzymes showed that the genome of Leptospira interrogans serovar canicola is approximately 3.1 Mb, while that of the saprophytic L. biflexa serovar patoc I is 3.5 Mb. DNA forms of approximately 2,000 and 350 kb which were present in samples from L. interrogans serovars were not readily detected in nonpathogenic serovars. Three distinct populations, designated type alpha, beta, and gamma, of L. interrogans DNA molecules were further analyzed with two-dimensional gel electrophoresis. Evidence suggested that two of these DNA forms, type alpha and gamma, were linear structures. Pulsed-field gel electrophoresis has proven to be a valuable tool with which to size bacterial genomes and to take the first steps toward characterization of a form of leptospiral DNA which behaves as a linear molecule and which may be related to the virulence of L. interrogans. AD - Department of Microbiology and Immunology, Bowman Gray School of Medicine, Wake Forest University Medical Center, Winston-Salem, North Carolina 27103. PMID- 1987046 CU - 92 SO - Infect Immun 1991 Jan;59(1):323-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 92070070 AU - Freudenstein H AU - Hein B TI - Potency of leptospiral vaccines and protection against chronic infection in golden hamsters. LA - Eng MH - Animal MH - *Bacterial Vaccines/standards MH - Female MH - Hamsters MH - Kidney/microbiology MH - Leptospira interrogans/*immunology/isolation & purification MH - Liver/microbiology MH - Mesocricetus MH - Spleen/microbiology MH - Weil's Disease/*prevention & control RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 920103 DP - 1991 IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 229-34 SB - M CY - ENGLAND IP - 3 VI - 14 JC - DNN AA - Author EM - 9203 AB - Seven vaccines prepared from pathogenic strains of different origin of Leptospira interrogans [serovars icterohaemorrhagiae (one strain) and copenhageni (6 strains)] were examined in protection tests on golden hamsters. Two of the copenhageni strains were used for challenge. The organs (kidneys, spleen, liver) in the vaccinated animals surviving challenge were protected to a varying degree. Low rates of survival were associated with a high incidence of Leptospira-positive findings, partly connected with focal lesions of the kidneys. On the other hand, in the groups in which all the animals survived, it was not possible to culture leptospires from their organs or to detect leptospiral antigen in these organs by immunohistochemical investigation. A protection of the organs that prevents vaccinated animals from shedding leptospires after infection clearly depends on the vaccine dose administered and the efficacy of the vaccine which can be measured in potency tests based on the survival rate as the relevant parameter. AD - Behringwerke AG, Marburg, Fed. Rep. Germany. PMID- 1959318 SO - Comp Immunol Microbiol Infect Dis 1991;14(3):229-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 92034274 AU - Hidou M TI - [Acute adult respiratory distress syndrome in leptospirosis] LA - Fre MH - Adolescence MH - Case Report MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*complications MH - Respiratory Distress Syndrome, Adult/*etiology PT - JOURNAL ARTICLE DA - 911213 DP - 1991 IS - 0007-7625 TA - Cah Anesthesiol PG - 281-4 SB - M CY - FRANCE IP - 4 VI - 39 JC - CBV AA - Author EM - 9202 AB - The respiratory manifestations of leptospirosis are usually benign. A case is reported of leptospirosis with serious pulmonary affection. Pulmonary involvement in leptospirosis is infrequently predominant and usually without bearing on prognosis. Clinical and roentgenological features are reviewed. Severe forms with massive hemoptysis or acute respiratory failure occur occasionally. The clinical symptoms, the radiological manifestations and haemodynamic investigation were suggestive of an acute respiratory distress by non haemodynamic pulmonary oedema. In accordance with other authors, one could be justified in including this acute respiratory failure as part of the adult respiratory distress syndrome. Since leptospirosis has extremely diverse clinical features, physicians should have this diagnosis in mind in many circumstances and should request the appropriate examinations at the right moment. Carefully performed microbiological techniques may reduce the problems encountered in isolating leptospires. Serological tests requested after the 12th day of the disease and repeated several times should improve the diagnosis confirmation. The potential severity of certain forms justifies curative antibiotic therapy. AD - Centre hospitalier des Armees, Jean Prince, SP. PMID- 1933530 TT - Syndrome de detresse respiratoire aigue de l'adulte au cours d'une leptospirose. EA - A SO - Cah Anesthesiol 1991;39(4):281-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 91352559 AU - Hancox RJ AU - Karalus N AU - Singh V TI - Mononeuritis multiplex in leptospirosis [letter] LA - Eng MH - Adult MH - Case Report MH - Human MH - *Leptospirosis MH - Male MH - Neuritis/*microbiology PT - LETTER DA - 911001 DP - 1991 IS - 0036-5548 TA - Scand J Infect Dis PG - 395-6 SB - M CY - SWEDEN IP - 3 VI - 23 JC - UCX EM - 9112 PMID- 1882206 SO - Scand J Infect Dis 1991;23(3):395-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 91348183 AU - Alves VA AU - Gayotto LC AU - Yasuda PH AU - Wakamatsu A AU - Kanamura CT AU - De Brito T TI - Leptospiral antigens (L. interrogans serogroup ictero-haemorrhagiae) in the kidney of experimentally infected guinea pigs and their relation to the pathogenesis of the renal injury. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Glycoproteins/analysis/immunology MH - Guinea Pigs MH - Immunohistochemistry MH - Kidney/microbiology/*pathology MH - Kidney Glomerulus/microbiology/pathology MH - Kidney Tubules/microbiology/pathology MH - Kinetics MH - Leptospira interrogans/immunology/*isolation & purification MH - Lipoproteins/analysis/immunology MH - Male MH - Nephritis, Interstitial/microbiology/*pathology MH - Weil's Disease/immunology/microbiology/*pathology RN - 0 (Antigens, Bacterial) RN - 0 (Glycoproteins) RN - 0 (Lipoproteins) PT - JOURNAL ARTICLE DA - 911003 DP - 1991 IS - 0232-1513 TA - Exp Pathol PG - 81-93 SB - M CY - GERMANY IP - 2 VI - 42 JC - EQR AA - Author EM - 9112 AB - The search for leptospiral antigens (L. interrogans serogroup icterohaemorrhagiae) was carried out in 24 guinea pigs experimentally inoculated with 1 ml of culture containing 10(7)-10(8) leprospires and sequentially sacrificed from the first until the 6th day of infection. Semiquantitative analysis of histopathological variables comprising kidney interstitium, tubules and glomeruli was done in 1 micron sections of tissue embedded in glycolmetacrylate. Leptospiral antigen (LAg) and its glycolipoprotein (GLP) expression were detected through PAP in paraffin embedded tissue. The mild interstitial involvement of the kidney, manifested chiefly by oedema and focal interstitial nephritis seen at the 4th day, progressed to tubular damage at the 6th day, characterized by either swelling or cytoplasmic acidophilia of epithelial cells with loss of cell cohesion and sloughing of cells into the tubular lumina. Brush border alterations and mitochondrial changes were observed. Endothelial cell injury was noted in the interstitial vessels. LAg expression was parallel to the kidney changes: small deposits of elongated forms of LAg were detected at the 4th day either within the vascular lumen or free in the interstitium. A rise in the antigen expression was observed at the 5th day when it was seen either around tubules or in their walls. LAg was detected inside the tubular lumina at the 6th day of infection when granular LAg and GLP were abundant. This sequence reproduces the pathway of leptospires in the kidney and the crescent amounts of antigens detected toward the end of the experiment, with antigen concentration in cases of major tissue damage suggesting a direct action of the microorganisms and/or their products in the pathogesis of the lesions. AD - Sao Paulo University, Medical School, Brazil. PMID- 1879516 CU - 91 SO - Exp Pathol 1991;42(2):81-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 91333406 AU - Masuzawa T AU - Suzuki R AU - Yanagihara Y TI - Comparison of protective effects with tetra-valent glycolipid antigens and whole cell-inactivated vaccine in experimental infection of Leptospira. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/immunology MH - Antigens, Bacterial/*immunology MH - Comparative Study MH - Cyclophosphamide/administration & dosage MH - Disease Models, Animal MH - Enzyme-Linked Immunosorbent Assay MH - Glycolipids/*immunology MH - Hamsters MH - Leptospira/*immunology MH - Leptospirosis/*immunology/prevention & control MH - Male MH - Mesocricetus MH - Mice MH - Opsonins/immunology MH - Support, Non-U.S. Gov't MH - Vaccines, Inactivated/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Glycolipids) RN - 0 (Opsonins) RN - 0 (Vaccines, Inactivated) RN - 50-18-0 (Cyclophosphamide) PT - JOURNAL ARTICLE DA - 910913 DP - 1991 IS - 0385-5600 TA - Microbiol Immunol PG - 199-208 SB - M CY - JAPAN IP - 3 VI - 35 JC - MX7 AA - Author EM - 9111 AB - The protective antigens (PAgs), glycolipid substance, were extracted from Leptospira interrogans serovars autumnalis, hebdomadis, australis and copenhageni, which were considered as main causal serovars of human leptospirosis in Japan, with chloroform-methanol-water (1:2:0.8, [vol/vol/vol]) solution. The tetra-valent formalin-inactivated leptospiral vaccine (Weil's disease and Akiyami combined vaccine) composed of the four serovars mentioned are used as vaccine to protect human from leptospiral infection in Japan. The protective effect, agglutinating antibody-inducing activity and opsonin-inducing activity of tetra-valent PAgs were compared with those of vaccines now in use, which were supplied by two companies, Takeda Chemical Industries, Ltd., and Denka-Seiken Co., in Japan. The tetra-valent PAgs which contained 10 micrograms of each PAg protected hamsters and cyclophosphamide- treated mice from lethal infection of serovar copenhageni and induced agglutinating antibodies against the four serovars in the same degrees as vaccines. These results suggested that the tetra-valent PAgs might be useful as a component vaccine against leptospiral infection instead of formalized whole cells vaccines for human. AD - Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka. PMID- 1870437 CU - 92 SO - Microbiol Immunol 1991;35(3):199-208 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 91326917 AU - Duval G AU - Michault A AU - Baranton G AU - Law-Koune JD AU - Folio G AU - Bertil G AU - Guiserix J TI - [Seroepidemiological study of human leptospirosis at Reunion Island] LA - Fre MH - Adolescence MH - Adult MH - Aged MH - Agricultural Workers' Diseases/immunology MH - Antibodies, Bacterial/isolation & purification MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Human MH - Indian Ocean Islands/epidemiology MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Prevalence MH - Rural Population MH - Seroepidemiologic Methods MH - Support, Non-U.S. Gov't MH - Weil's Disease/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910912 DP - 1991 IS - 0398-7620 TA - Rev Epidemiol Sante Publique PG - 135-41 SB - M CY - FRANCE IP - 2 VI - 39 JC - RST AA - Author EM - 9111 AB - In order to evaluate the prevalence of human leptospirosis in Reunion island and to identify possible risk factors, a study was realised on a representative population sample of 3.338 persons. The prevalence of leptospirosis, diagnosed by ELISA and confirmed by Micro Agglutination Test, was 1.1%. Male predominance and higher prevalence in rainy parts of the island, were confirmed. It has not been possible to display risk factors such as housing conditions or professional exercise. The serological repartition showed not only icterohaemorrhagiae serovar, but also canicola, panama and sejroe, especially in women. These results, compared with clinical studies (showing nearly exclusive male repartition, in agricultural workers, due to icterohaemorrhagiae serovar), confirm the double look of human leptospirosis in Reunion island: clinical leptospirosis, severe, concerning males, often countrymen, due to icterohaemorrhagiae serovar, and infraclinical leptospirosis, concerning principally females, which is a domestic illness, due to other serovars. AD - Unite de Reanimation, Hopital Rothschild, Paris. PMID- 1866480 CU - 91 TT - Etude sero epidemiologique de la leptospirose humaine a l'ile de laReunion. EA - A SO - Rev Epidemiol Sante Publique 1991;39(2):135-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 91313089 AU - Vuong TK AU - Laaban JP AU - Rabbat A AU - Capron F AU - Bouvet A AU - Rochemaure J TI - [Icterohemorrhagic leptospirosis with acute respiratory distress syndrome and pulmonary hemorrhage] LA - Fre MH - Adult MH - Case Report MH - English Abstract MH - *Hemorrhage/pathology MH - Human MH - *Lung Diseases/pathology MH - Male MH - *Respiratory Distress Syndrome, Adult/pathology MH - *Weil's Disease/pathology PT - JOURNAL ARTICLE DA - 910829 DP - 1991 IS - 0761-8425 TA - Rev Mal Respir PG - 256-7 SB - M CY - FRANCE IP - 2 VI - 8 JC - RZ9 AA - Author EM - 9110 AB - We report a case of the respiratory distress syndrome occurring in a patient with leptospirosis ictero-haemorrhagica (LIH). The respiratory failure was associated with pulmonary haemorrhage. There was a rapid favourable outcome after treatment with antibiotics and artificial ventilation. The diagnosis of LIH has been confirmed by serological examination. The mechanisms of the pulmonary disorder during the course of LIH were discussed. AD - Service de Pneumologie et Reanimation, Hotel-Dieu, Paris. PMID- 1857821 TT - Leptospirose icterohemorragique avec syndrome de detresse respiratoire aigue et hemorragie pulmonaire. EA - A SO - Rev Mal Respir 1991;8(2):256-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 92385261 AU - Zhao LG AU - Yanagihara R AU - Mora C AU - Garruto RM AU - Wong TW AU - Gajdusek DC TI - Prevalence of human T-cell lymphotropic virus type I infection in Singapore: a preliminary report. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Antibodies, Viral/blood MH - Blotting, Western MH - Child MH - Child, Preschool MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Hospitals, General MH - Human MH - HTLV-I Infections/blood/*epidemiology/immunology MH - IgG/immunology MH - Male MH - Middle Age MH - Prevalence MH - Seroepidemiologic Methods MH - Singapore/epidemiology RN - 0 (Antibodies, Viral) RN - 0 (IgG) PT - JOURNAL ARTICLE DA - 921007 DP - 1991 IS - 1010-5395 TA - Asia Pac J Public Health PG - 236-8 CY - HONG KONG IP - 3 VI - 5 JC - ASJ AA - Author EM - 9212 AB - Human T-cell lymphotropic virus type I (HTLV-I) infection is endemic in southwestern Japan, the Caribbean basin, Colombia, Africa and in several isolated populations in Papua New Guinea, the Solomon Islands and Vanuatu. To determine the seroprevalence of HTLV-I infection in Singapore, we tested sera from 115 hospitalized patients with acute nephritis, 50 patients with suspected leptospirosis, 34 patients with non-A, non-B hepatitis, and from 28 healthy volunteers for IgG antibodies against HTLV-I using an enzyme-linked immunosorbent assay. Antibodies were detected in sera from 6 of the 199 patients and from 3 of the 28 healthy volunteers, but these positives could not be confirmed by Western immunoblotting. Our data are consistent with other reports of low seroprevalence of HTLV-I infection despite extensive Japanese contact in Korea, Taiwan, the People's Republic of China and Micronesia. Further studies on a larger sample size, however, are necessary to confirm the absence of any focus of infection in the Singapore population. AD - Laboratory of Central Nervous System Studies, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892. PMID- 1823807 SO - Asia Pac J Public Health 1991;5(3):236-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 92114399 AU - Dekhtiar' AL AU - Kadyshev IuG AU - Roik IaI AU - Surmach VV TI - [Difficulties in the differential diagnosis of leptospirosis and acute surgical pathology of the bile ducts] LA - Rus MH - Acute Disease MH - Bile Duct Diseases/*diagnosis/surgery MH - Case Report MH - Diagnosis, Differential MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 920220 DP - 1991 IS - 0023-2130 TA - Klin Khir PG - 66-7 CY - USSR IP - 9 JC - KVV EM - 9204 PMID- 1766189 TT - Trudnosti differentsial'noi diagnostiki leptospiroza i ostryi khirurgicheskoi patologii zhelchevyvodiashchikh putei. SO - Klin Khir 1991;(9):66-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 91333400 AU - Kobayashi Y AU - Sada E AU - Tamai T TI - Serological studies on Leptospira strain Ictero No. I using monoclonal antibodies. LA - Eng MH - Agglutination MH - Antibodies, Monoclonal/*immunology MH - Antigens, Bacterial/*analysis MH - Epitopes MH - Human MH - Hybridomas/immunology MH - Leptospira/*immunology RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 910917 DP - 1991 IS - 0385-5600 TA - Microbiol Immunol PG - 67-76 SB - M CY - JAPAN IP - 1 VI - 35 JC - MX7 AA - Author EM - 9111 AB - In order to elucidate the full serological characteristics of strain Ictero No. I, the first strain of Leptospira isolated by Inada and Ido in 1914, 17 monoclonal antibodies against the strain were produced by cell fusion technology. The antibody-producing hybridomas were designated IMAs 1 to 17. The reactivities of the monoclonal antibodies produced by the hybridomas were determined by the microscopic agglutination test. One of the 17 monoclonal antibodies, IMA 1, reacted with strains Ictero No. I, LT 1131 and Naam, but not with other strains of the serogroup Icterohaemorrhagiae including strain RGA used in the present study. Moreover, the reactivity of the antigenic determinant of IMA 1 was inactivated by treatment at 56 C for 30 min. The 16 other monoclonal antibodies, IMAs 2 to 17, showed different reaction patterns against Leptospira strains of the serogroup Icterohaemorrhagiae. All of the 16 antibodies reacted with both Ictero No. I and RGA strains. The antigens against antibodies IMAs 2 to 17 were thermostable. The present study thus clarified the presence of a thermolabile antigen in strain Ictero No. I, and allowed correct distinction between the serotype of strain Ictero No. I and that of strain RGA using IMA 1. Therefore, we propose that strain Ictero No. I represents serovar icterohaemorrhagiae, as originally designated by Inada and Ido. Moreover, strain Ictero No. I should be designated as the type strain of Leptospira interrogans. AD - First Department of Internal Medicine, School of Medicine, Ehime University. PMID- 1714535 CU - 95 SO - Microbiol Immunol 1991;35(1):67-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 91061662 AU - Chen SC AU - Mitchell DH AU - Dickeson DJ AU - Cunningham AL TI - Severe respiratory and renal failure in serovar hardjo related leptospirosis [letter] LA - Eng MH - Adult MH - Case Report MH - Human MH - Kidney Failure, Acute/*etiology MH - Leptospira/classification MH - Leptospirosis/*complications MH - Male MH - Respiratory Insufficiency/*etiology/microbiology MH - Serotyping PT - LETTER DA - 910110 DP - 1990 Dec 3-17 IS - 0025-729X TA - Med J Aust PG - 743 SB - M SB - X CY - AUSTRALIA IP - 11-12 VI - 153 JC - M26 EM - 9103 PMID- 2247011 SO - Med J Aust 1990 Dec 3-17;153(11-12):743 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 97175188 AU - Myburgh JG AU - Otto QT TI - Serological survey for bovine leptospirosis in the Volksrust district. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*blood MH - Cattle MH - Cattle Diseases/*epidemiology MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Prevalence MH - South Africa/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 970305 DP - 1990 Dec IS - 0301-0732 TA - J S Afr Vet Assoc PG - 172-3 SB - M CY - SOUTH AFRICA IP - 4 VI - 61 JC - JZH AA - Author EM - 9705 AB - Serum samples (n = 860) from cattle in the Volksrust district were tested for Leptospira antibody titres. Seventeen (2%) of the animals were positive for leptospirosis, while 9(1%) animals showed suspect reactions. Titres against L. hardjo, L. pomona, and L. tarassovi were the most prevalent. AD - Reproduction section, Veterinary Research Institute, Onderstepoort, Republic of South Africa. PMID- 9022848 NP - X SO - J S Afr Vet Assoc 1990 Dec;61(4):172-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 91156283 AU - Myburgh JG AU - Bengis RG AU - Bester CJ AU - Chaparro F TI - Serological reactions to Leptospira species in buffalo (Syncerus caffer) from the Kruger National Park. LA - Eng MH - Animal MH - Buffaloes/*immunology MH - Cattle MH - Cattle Diseases/transmission MH - Leptospira/*immunology MH - Leptospirosis/transmission/*veterinary MH - Seroepidemiologic Methods MH - South Africa PT - JOURNAL ARTICLE DA - 910411 DP - 1990 Dec IS - 0030-2465 TA - Onderstepoort J Vet Res PG - 281-2 SB - M CY - SOUTH AFRICA IP - 4 VI - 57 JC - OI6 AA - Author EM - 9106 AB - Four hundred and six serum samples from buffalo (Syncerus caffer) were tested for leptospirosis, using the microscopic agglutination test. Seven buffaloes (1.7%) reacted positive and 27 (6.6%) inconclusive. Reactions against L. tarassovi and L. hardjo were the most prevalent. AD - Veterinary Research Institute, Onderstepoort. PMID- 2293138 SO - Onderstepoort J Vet Res 1990 Dec;57(4):281-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 91126953 AU - Murray RD TI - A field investigation of causes of abortion in dairy cattle. LA - Eng MH - Abortion, Veterinary/*etiology/pathology MH - Animal MH - Cattle MH - Cattle Diseases/*etiology/pathology MH - Female MH - Fetal Membranes/microbiology MH - Fetus/*pathology MH - Infection/diagnosis/veterinary MH - Placenta/microbiology MH - Pregnancy PT - JOURNAL ARTICLE DA - 910314 DP - 1990 Dec 1 IS - 0042-4900 TA - Vet Rec PG - 543-7 SB - M CY - ENGLAND IP - 22 VI - 127 JC - XBS AA - Author EM - 9105 AB - Cases of abortion on dairy farms on the Lancashire/Cumbria border were investigated by means of a systematic diagnostic procedure, using the facilities of a veterinary practice's laboratory, and the Ministry of Agriculture, Fisheries and Food veterinary investigation centre. Among approximately 3600 animals, 149 abortions were investigated on 54 farms in two years, an annual abortion rate of 2 per cent. A diagnosis was made in 34 per cent of the cases, based on a pathological examination of aborted material and bacteriological and serological findings. The most common pathogens associated with abortion were bovine viral diarrhoea virus (39 cases), bacterial or fungal infections (20 cases), infectious bovine rhinotracheitis virus (19 cases), and Leptospira hardjo (18 cases), either as single or multiple infections. AD - University of Liverpool, Department of Veterinary Clinical Science, Leahurst, Neston, South Wirral. PMID- 2281595 SO - Vet Rec 1990 Dec 1;127(22):543-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 91116173 AU - Coyle PK AU - Dattwyler R TI - Spirochetal infection of the central nervous system. LA - Eng MH - *Central Nervous System Diseases MH - Human MH - *Leptospirosis MH - *Lyme Disease MH - *Neurosyphilis MH - *Relapsing Fever MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 910306 DP - 1990 Dec IS - 0891-5520 TA - Infect Dis Clin North Am PG - 731-46 SB - M CY - UNITED STATES IP - 4 VI - 4 JC - IDC AA - Author EM - 9105 AB - Four spirochetal diseases frequently involve the central nervous system: syphilis, leptospirosis, relapsing fever, and Lyme borreliosis. In particular, syphilis and Lyme borreliosis are increasing problems. During the spirochetemic phase there is seeding of the nervous system. After a quiescent latent period, there may be late disease flareups producing a variety of neurologic syndromes. Cerebrospinal fluid examination is very helpful in these infections. AD - Health Sciences Center, State University, New York, Stony Brook. RF - 55 PMID- 2277196 SO - Infect Dis Clin North Am 1990 Dec;4(4):731-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 91281290 AU - Agaev IA TI - [The self-maintenance of natural foci of leptospirosis] LA - Rus MH - Animal MH - Animals, Wild MH - Antibodies, Bacterial/blood MH - Antibody Specificity MH - Azerbaijan/epidemiology MH - Disease Reservoirs/statistics & numerical data/*veterinary MH - English Abstract MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/epidemiology/immunology/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910726 DP - 1990 Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 40-4 SB - M CY - USSR IP - 12 JC - Y9O AA - Author EM - 9110 AB - The specificity of infection of individual species of small mammals with definite serogroups of leptospires has been shown. The intensity of the epizootic process has been found to depend on the number of animals in the population. The mechanisms of the self-regulation of the epizootic process in natural foci are explained. PMID- 2151555 CU - 92 TT - Samopodderzhanie prirodnykh ochagov leptospiroza. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1990 Dec;(12):40-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 92096726 AU - Ezeh AO AU - Kmety E AU - Ellis WA AU - Addo PB AU - Adesiyun AA TI - A new leptospiral serovar in the Pyrogenes serogroup isolated in Nigeria. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Kidney/microbiology MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Nigeria MH - Serotyping PT - JOURNAL ARTICLE DA - 920131 DP - 1990 Dec IS - 0253-1933 TA - Rev Sci Tech PG - 1195-6 SB - M CY - FRANCE IP - 4 VI - 9 JC - A9R AA - Author EM - 9204 AB - Five leptospiral strains were isolated from bovine kidneys during a cultural survey for pathogenic leptospires in Nigeria. Preliminary test results indicated that the five strains were identical and serologically heterologous to the other members of the Pyrogenes serogroup. Further examination of the strains by the cross-agglutinin absorption test, factor analysis and restriction endonuclease analysis confirmed that the strains constitute a new serovar. It is therefore proposed that this strain be recognised and designated as serovar nigeria, type strain Vom. AD - Leptospirosis Section, National Veterinary Research Institute, Vom, Nigeria. PMID- 2132712 SO - Rev Sci Tech 1990 Dec;9(4):1195-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 91065424 AU - Stanford CF AU - Connolly JH AU - Ellis WA AU - Smyth ET AU - Coyle PV AU - Montgomery WI AU - Simpson DI TI - Zoonotic infections in Northern Ireland farmers. LA - Eng MH - Adult MH - Aged MH - Aged, 80 and over MH - Agricultural Workers' Diseases/*epidemiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Protozoan/analysis MH - Antibodies, Viral/analysis MH - Borrelia burgdorferi/immunology MH - Brucella/immunology MH - Chlamydia psittaci/immunology MH - Coxiella/immunology MH - Hantavirus/immunology MH - Human MH - Leptospira interrogans/immunology MH - Middle Age MH - Northern Ireland/epidemiology MH - Risk Factors MH - Support, Non-U.S. Gov't MH - Toxoplasma/immunology MH - *Zoonoses RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Protozoan) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 910117 DP - 1990 Dec IS - 0950-2688 TA - Epidemiol Infect PG - 565-70 SB - M CY - ENGLAND IP - 3 VI - 105 JC - EPI AA - Author EM - 9103 AB - Evidence of past zoonotic infection was investigated serologically in randomly selected Northern Ireland farmers. The percentage of farmers with antibody was: Brucella abortus (0.7), Leptospira interrogans serovars (8.1), Borrelia burgdorferi (14.3), Toxoplasma gondii (73.5), Coxiella burnetii (28.0), Chlamydia psittaci (11.1) and Hantavirus (1.2). The results show that Northern Ireland farmers have been exposed in the past to zoonotic infections. It is not known if these infections contributed to ill health in farmers but it is now time for the health of farm workers and their medical services to be reassessed. AD - Royal Victoria Hospital, Belfast, Northern Ireland. PMID- 2123457 CU - 91 SO - Epidemiol Infect 1990 Dec;105(3):565-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 91281298 AU - Volina EG AU - Mel'nitskaia EV AU - Bernasovskaia EP AU - Kiktenko VS AU - Arimitsu Y AU - Kobayachi S TI - [A comparative evaluation of the sensitivity of different methods for the serological diagnosis of leptospirosis] LA - Rus MH - Agglutination Tests/instrumentation/methods MH - Antibodies, Bacterial/blood MH - Comparative Study MH - Diagnosis, Differential MH - English Abstract MH - Evaluation Studies MH - Hemagglutination Tests MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis MH - Serodiagnosis/methods MH - Time Factors MH - Weil's Disease/diagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910726 DP - 1990 Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 73-7 SB - M CY - USSR IP - 12 JC - Y9O AA - Author EM - 9110 AB - In this work the comparative evaluation of the sensitivity and serological specificity of the microcapsular agglutination (MCA) test, the passive hemagglutination (PHA) test and the microagglutination (MA) test are presented. In the MCA test leptospiral antigens, adsorbed on synthetic carrier capsules produced by Japan Lyophilization Laboratory, were used and the PHA test was made with the use of polyvalent erythrocyte diagnosticum. The study of blood serum samples from 46 leptospirosis patients revealed that the values of antibody titers in the PHA and MCA tests were 5.5-8.1 times higher than the traditional MA test. In the MCA and PHA tests antileptospiral antibodies could be detected as early as on days 1-3 of the disease when the results of the MA test were negative or very low. The maximum values of antibody titers in the MCA and PHA tests were detected on days 11-15 of the disease and in the MA test, on days 21-25. The MCA and PHA tests are genus-specific and permit the detection of antileptospiral antibodies irrespective of the serogroup of the infective agent. In the study of the blood sera of 40 patients with diseases of nonleptospiral etiology the MCA and MA tests yielded false positive results in 7.5% and the PHA test, in 12.5% of cases in titers below the diagnostic level. These data are indicative of high sensitivity and specificity of the serological tests used in this study. PMID- 2099075 CU - 91 TT - Sravnitel'naia otsenka chuvstvitel'nosti razlichnykh metodov serologichicheskoi diagnostiki leptospiroza. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1990 Dec;(12):73-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 91274422 AU - Mariscal D AU - Trilla A AU - Mensa J AU - Pumarola T AU - Moya X AU - Soriano E AU - Jimenez de Anta MT TI - [Severe leptospirosis. Description of a series of 10 cases] LA - Spa MH - Aged MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis/drug therapy MH - Male MH - Middle Age MH - Retrospective Studies PT - JOURNAL ARTICLE DA - 910731 DP - 1990 Dec IS - 0213-005X TA - Enferm Infecc Microbiol Clin PG - 602-5 CY - SPAIN IP - 10 VI - 8 JC - A10 AA - Author EM - 9110 AB - Clinical aspects of 10 consecutive patients hospitalized for acute human leptospirosis, confirmed by serology using the microscopic agglutination test (MAT), between 1975 and 1988 in a 1000 beds Teaching Hospital are retrospectively analyzed. All of them were male, mean age of 55, presenting a suggestive epidemiological data to be at risk for Leptospira infection. Leptospira icterohaemorrhagiae was responsible for 8 cases and Leptospira canicola for 2. 7 patients were treated, after 3-4 days of admittance, with penicillin. 5 patients died. Cause of death was gastrointestinal haemorrhage in 3 and cardiogenic shock in 2. We discuss the clinical, biochemical, pathological and therapeutic aspects of the acute human leptospirosis. AD - Servicio de Enfermedades Infecciosas, Hospital Clinic i Provincial, Universidad de Barcelona. PMID- 2098117 TT - Leptospirosis grave. Descripcion de una serie de 10 casos. EA - A SO - Enferm Infecc Microbiol Clin 1990 Dec;8(10):602-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 91274421 AU - Lopez Brea M AU - Sanz JC TI - [Leptospirosis (editorial)] LA - Spa MH - Animal MH - Disease Reservoirs MH - Human MH - *Leptospirosis/diagnosis/drug therapy/microbiology PT - EDITORIAL DA - 910731 DP - 1990 Dec IS - 0213-005X TA - Enferm Infecc Microbiol Clin PG - 597-601 CY - SPAIN IP - 10 VI - 8 JC - A10 EM - 9110 PMID- 2098116 TT - Leptospirosis. SO - Enferm Infecc Microbiol Clin 1990 Dec;8(10):597-601 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 91188718 AU - Hiramune T AU - Shiraiwa C AU - Kikuchi N AU - Yanagawa R TI - A basic study of chemotaxis of leptospiras. LA - Eng MH - *Chemotaxis MH - Culture Media MH - Hemoglobins/metabolism MH - Leptospira interrogans/*physiology RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 910506 DP - 1990 Dec IS - 0931-1793 TA - Zentralbl Veterinarmed [B] PG - 749-52 CY - GERMANY IP - 10 VI - 37 JC - Y72 AA - Author EM - 9107 AB - Chemotaxis of leptospiras was studied using a U-tube made of a commercially available straw-shaped polypropylene tube with an uneven flexible part. The U-tube was made by folding the polypropylene tube double and binding the vertical parts by a piece of tape, thus making the uneven flexible part the bottom. Semi-solid Korthof's medium was poured into the U-tube. Preliminary experiments showed that the medium containing 0.5% agar and measuring 2 cm in in length was appropriate. Leptospiras inoculated on the top of the medium of one side of the U- tube moved toward the top of the medium of the other side. The leptospiral move toward the uninoculated top was significantly faster when 6 micrograms of hemoglobin were added to the uninoculated top. Chemotaxis of leptospiras to hemoglobin was thus shown, which is the first evidence of chemotaxis of leptospiras. AD - School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan. PMID- 2082627 CU - 91 SO - Zentralbl Veterinarmed [B] 1990 Dec;37(10):749-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 91180950 AU - Alexander CS AU - Keller H TI - [Etiology and occurrence of periodic eye inflammation of horses in the area of Berlin] LA - Ger MH - Age Factors MH - Animal MH - Antibodies, Bacterial/blood MH - Antibodies, Helminth/blood MH - Antibodies, Protozoan/blood MH - Berlin/epidemiology MH - Endophthalmitis/epidemiology/etiology/*veterinary MH - English Abstract MH - Female MH - Horse Diseases/epidemiology/*etiology MH - Horses MH - Intestinal Diseases, Parasitic/epidemiology/veterinary MH - Leptospira/immunology MH - Leptospirosis/epidemiology/veterinary MH - Male MH - Seasons MH - Sex Factors MH - Toxoplasma/immunology MH - Toxoplasmosis, Animal/epidemiology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Helminth) RN - 0 (Antibodies, Protozoan) PT - JOURNAL ARTICLE DA - 910426 DP - 1990 Dec IS - 0303-6286 TA - Tierarztl Prax PG - 623-7 SB - M CY - GERMANY IP - 6 VI - 18 JC - VS4 AA - Author EM - 9107 AB - Over 130 cases of equine periodic ophthalmia (p.o.), which were treated as in-patients at the Equine Clinic of the Free University of Berlin in the last 35 years, were examined statistically in relation to the age and gender of the animals involved as well as to the development of the illness and the season in which it arose. As regards aetiology, the extraction of 71 affected Trotters was investigated. Antibodies to toxoplasmosis, leptospirosis and intestinal parasites were found only in some of the patients. Younger animals, aged between one and four years, and male animals (63.6%) were predominantly affected. The results of the examinations of faeces showed no correlation between cases of p.o. and a vermination of the horses. The examinations for antibodies to toxoplasmosis gave no indication of a participation of the toxoplasmas in the aetiology of recurrent uveitis. In contrast, the results of the examinations for antibodies to leptospirosis, of which 58.8% were positive, showed a seven to ten times higher infection than in healthy horses in Berlin. Breed analysis showed that in certain breeds of Trotters and warm-blooded horses, p.o. illnesses were frequent, supporting the hypothesis that the occurrence of p.o. is due to a hereditary, allergic reaction, triggered by various factors, in particular an infection without clinical signs. AD - Klinik fur Pferde, Allgemeine Chirurgie und Radiologie, Freien Universitat Berlin. PMID- 2080508 CU - 91 TT - Atiologie und Vorkommen der periodischen Augenentzundung des Pferdes im Raum Berlin. EA - A SO - Tierarztl Prax 1990 Dec;18(6):623-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 91162026 AU - Kawaguchi S AU - Uragami K AU - Mizuno W AU - Tsuji Y AU - Aizawa K AU - Shioji N AU - Nishioka S AU - Yataka I TI - [A case of Akiyami C disease, infected in the area of Yoshino] LA - Jpn MH - Antibodies, Bacterial/analysis MH - Case Report MH - English Abstract MH - Human MH - Leptospira/immunology MH - Male MH - Middle Age MH - Weil's Disease/*diagnosis/immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910412 DP - 1990 Dec IS - 0387-5911 TA - Kansenshogaku Zasshi PG - 1572-5 CY - JAPAN IP - 12 VI - 64 JC - IJR AA - Author EM - 9106 AB - A 47-year-old male was admitted because of persistent jaundice. Akiyami C disease was diagnosed by serological tests using the microscopic agglutination tests. The source was considered to be a water contaminated with leptospiras which he had drunk while working at a civil engineering job. The reported cases of Akiyami C disease have recently decreased and this is the 6th case reported in the last 15 years. AD - Department of Internal Medicine, Hashimoto Municipal Hospital. PMID- 2074376 CU - 91 EA - A SO - Kansenshogaku Zasshi 1990 Dec;64(12):1572-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 91131176 AU - Venugopal K AU - Ratnam S TI - Lesions and immune responses produced in hamsters and guinea pigs inoculated with some strains of leptospira. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Bacterial Vaccines/*immunology MH - Female MH - Guinea Pigs MH - Hamsters MH - Kidney/pathology MH - Leptospira/*immunology/pathogenicity MH - Liver/pathology MH - Male MH - Support, Non-U.S. Gov't MH - Virulence RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 910315 DP - 1990 Nov IS - 0019-5189 TA - Indian J Exp Biol PG - 1075-7 CY - INDIA IP - 11 VI - 28 JC - GIZ AA - Author EM - 9105 AB - Pathogenic lesions and immune responses in hamsters and guinea pigs produced by three leptospiral serovars, viz. autumnalis, grippotyphosa, and pomona, and their pool were experimentally studied. Hepatic lesions precede renal localisation. The infections were documented by the demonstration of leptospires and histopathological study. The 2-Me sensitive IgM was responsible for MAT titres in the early immune response. AD - Department of Preventive Medicine and Microbiology, Madras Veterinary College, India. PMID- 2283174 CU - 91 SO - Indian J Exp Biol 1990 Nov;28(11):1075-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 91086515 AU - Laing RW AU - Teh C AU - Toh CH TI - Thrombotic thrombocytopenic purpura (TTP) complicating leptospirosis: a previously undescribed association [letter] LA - Eng MH - Case Report MH - Human MH - Kidney Tubules/pathology MH - Leptospirosis/*complications/pathology MH - Male MH - Middle Age MH - Purpura, Thrombotic Thrombocytopenic/*complications/pathology PT - LETTER DA - 910201 DP - 1990 Nov IS - 0021-9746 TA - J Clin Pathol PG - 961-2 SB - A SB - M SB - X CY - ENGLAND IP - 11 VI - 43 JC - HT3 EM - 9104 PMID- 2262572 SO - J Clin Pathol 1990 Nov;43(11):961-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 91066332 AU - Midwinter A AU - Faine S AU - Adler B TI - Vaccination of mice with lipopolysaccharide (LPS) and LPS-derived immuno-conjugates from Leptospira interrogans. LA - Eng MH - Animal MH - Antigens, Bacterial/immunology MH - Diphtheria Toxin/therapeutic use MH - Electrophoresis, Polyacrylamide Gel MH - Immunity, Active MH - Immunotoxins MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/*prevention & control MH - Lipopolysaccharides/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Polysaccharides/immunology MH - Support, Non-U.S. Gov't MH - *Vaccination RN - 0 (Antigens, Bacterial) RN - 0 (Diphtheria Toxin) RN - 0 (Immunotoxins) RN - 0 (Lipopolysaccharides) RN - 0 (Polysaccharides) PT - JOURNAL ARTICLE DA - 910116 DP - 1990 Nov IS - 0022-2615 TA - J Med Microbiol PG - 199-204 SB - M CY - ENGLAND IP - 3 VI - 33 JC - J2N AA - Author EM - 9103 AB - Mice were vaccinated with lipopolysaccharide (LPS) from Leptospira interrogans serovar pomona or hardjo, or with the polysaccharide (PS) fraction of the LPS, or with an immunoconjugate of PS and diphtheria toxoid (DT). Maximum agglutinin titres were found 6-10 weeks after vaccination with LPS or PS-DT conjugate; the latter elicited antibody titres at least 10 times higher than those produced in response to LPS. Animals failed to react significantly to PS. Titres elicited by antigens of serovar pomona were higher than those elicited by serovar hardjo. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 2250290 CU - 92 SO - J Med Microbiol 1990 Nov;33(3):199-204 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 92245326 AU - de Lima SC AU - Sakata EE AU - Santo CE AU - Yasuda PH AU - Stiliano SV AU - Ribeiro FA TI - [Outbreak of human leptospirosis by recreational activity in the municipality of Sao Jose dos Campos, Sao Paulo. Seroepidemiological study] LA - Por MH - Agglutination Tests MH - Brazil/epidemiology MH - *Disease Outbreaks MH - English Abstract MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - *Swimming Pools MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 920604 DP - 1990 Nov-Dec IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 474-9 CY - BRAZIL IP - 6 VI - 32 JC - S9D AA - Author EM - 9208 AB - An outbreak of human leptospirosis due to recreational activities occurred at Sao Jose dos Campos, Sao Paulo, Brazil in November 1987. It involved a group of persons who had participated in a gathering in a suburb club which had a swimming pool fed with natural water. Epidemiological investigation was carried out and laboratory tests from the patients were done. It was observed that a high prevalence of the pomona serotype (91%) was found in the serological analyses, while the presence of the agent of the infection could not be found in the water club swimming pool. AD - Centro de Saude I de Sao Jose dos Campos, Sao Paulo, Brasil. PMID- 2135496 TT - Surto de leptospirose humana por atividade recreacional no municipio de Sao Jose dos Campos, Sao Paulo. Estudo soroepidemiologico. EA - A SO - Rev Inst Med Trop Sao Paulo 1990 Nov-Dec;32(6):474-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 91052109 AU - Duffy PE AU - Le Guillouzic H AU - Gass RF AU - Innis BL TI - Murine typhus identified as a major cause of febrile illness in a camp for displaced Khmers in Thailand. LA - Eng MH - Adult MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/analysis MH - Cambodia/ethnology MH - Child MH - Female MH - Fever/etiology MH - Human MH - IgG/analysis MH - IgM/analysis MH - Male MH - *Refugees MH - Rickettsia typhi/immunology MH - Support, U.S. Gov't, Non-P.H.S. MH - Thailand MH - Typhus, Endemic Flea-Borne/diagnosis/*epidemiology/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 901224 DP - 1990 Nov IS - 0002-9637 TA - Am J Trop Med Hyg PG - 520-6 SB - A SB - M CY - UNITED STATES IP - 5 VI - 43 JC - 3ZQ AA - Author EM - 9102 AB - Scrub and murine typhus have been identified as causes of illness among the 238,000 displaced Khmer people residing in temporary settlements on the Thai side of the Thai-Cambodian border. Still, the true extent of the problem and the relative frequency of infection with scrub typhus as compared to murine typhus are unknown. We evaluated consecutive patients with unexplained pyrexia (documented fever, no exclusionary diagnosis, and constitutional symptoms) in 1 temporary settlement over 1 month. Laboratory studies included culture of blood and assay of paired sera for rickettsial IgM and IgG antibody, for dengue IgM and IgG antibody, and for leptospiral IgM and IgG antibody. Among 37 patients (27 adults and 10 children), 28 (75%) had a rickettsiosis (26 cases of murine typhus and 2 cases of scrub typhus). No case of enteric fever, dengue, or leptospirosis was diagnosed. The illnesses of 9 patients were not identified. Signs and symptoms did not distinguish confirmed rickettsial infections from undiagnosed illnesses. The 1 month attack rate of rickettsial infection was 29/100,000 for children and 185/100,000 for adults. Murine typhus was a major cause of febrile illness in this settlement. AD - Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand. PMID- 2122749 CU - 91 SO - Am J Trop Med Hyg 1990 Nov;43(5):520-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 91227634 AU - Saint Girons I AU - Margarita D AU - Amouriaux P AU - Baranton G TI - First isolation of bacteriophages for a spirochaete: potential genetic tools for Leptospira. LA - Eng MH - Bacteriophages/*isolation & purification/pathogenicity/ultrastructure MH - DNA/analysis MH - Electrophoresis, Agar Gel MH - Leptospira MH - Microscopy, Electron MH - Molecular Weight MH - Nucleic Acid Hybridization MH - Support, Non-U.S. Gov't MH - Virulence RN - 9007-49-2 (DNA) PT - JOURNAL ARTICLE DA - 910611 DP - 1990 Nov-Dec IS - 0923-2508 TA - Res Microbiol PG - 1131-8 SB - M CY - FRANCE IP - 9 VI - 141 JC - R6F AA - Author EM - 9108 AB - Three bacteriophages of the saprophytic aquicole bacterium Leptospira biflexa were isolated from sewage waters from the outskirts of Paris, France. These phages do not infect representative strains of the pathogenic species Leptospira interrogans, and their host range is restricted to serovar patoc of the saprophytic species. The phages were found to be lytic and no lysogenic state could be demonstrated. Electron micrographs showed that the phages were morphologically identical and had polyhedral heads and contractile tails. Their genomes were sensitive to restriction enzymes and consisted of double-stranded DNA. Pulsed-field agarose gel electrophoresis indicated that their genomes were linear: 60 kb for LE1 and 50 kb for LE3 and LE4. AD - Unite des Leptospires, Institut Pasteur, Paris. PMID- 2092364 SO - Res Microbiol 1990 Nov-Dec;141(9):1131-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 91219808 AU - Quinones Ortiz L AU - Gonzalez Avedillo J AU - Guerra JL AU - Mostaza JL TI - [THe detection of leptospirosis with kidney failure cardiac arrhythmia (letter)] LA - Spa MH - Arrhythmia/*etiology MH - Case Report MH - Female MH - Human MH - Kidney Failure, Acute/*etiology MH - Middle Age MH - Weil's Disease/*complications/diagnosis PT - LETTER DA - 910606 DP - 1990 Nov IS - 0014-2565 TA - Rev Clin Esp PG - 429 CY - SPAIN IP - 8 VI - 187 JC - RNL EM - 9108 PMID- 2091138 TT - Deteccion de leptospirosis con fracaso renal tras arritmia cardiaca. SO - Rev Clin Esp 1990 Nov;187(8):429 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 91192591 AU - Hookey JV TI - The detection of genetic variation in Leptospira interrogans serogroup ICTEROHAEMORRHAGIAE by ribosomal RNA gene restriction fragment patterns. LA - Eng MH - DNA Probes MH - Genes, Structural MH - Genetic Markers MH - Leptospira interrogans/*genetics MH - Phylogeny MH - *Polymorphism, Restriction Fragment Length MH - Restriction Mapping MH - RNA, Ribosomal/*chemistry MH - *Variation (Genetics) RN - 0 (DNA Probes) RN - 0 (Genetic Markers) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE DA - 910510 DP - 1990 Nov IS - 0378-1097 TA - FEMS Microbiol Lett PG - 329-35 SB - M CY - NETHERLANDS IP - 3 VI - 60 JC - FML AA - Author EM - 9107 AB - Deoxyribonucleic acid from Leptospira interrogans serogroup ICTEROHAEMORRHAGIAE reference strains together with clinical and animal isolates were cleaved with EcoRI, electrophoresed and transferred to nylon membranes. An Escherichia coli MRE 600, 16S + 23S ribosomal RNA template was used in the synthesis of a single strand biotin-labelled cDNA probe using a reverse transcriptase. Ribosomal RNA cistrons present in the DNA fragments of strains were located using the cDNA probe. Between 4 and 7 well defined ribosomal RNA restriction bands were detected for the leptospires studied that varied in size from 12.1 to 0.57 kb. The hybridisation patterns were distinctive and unique for the reference strains that allowed for their characterisation. Similar patterns were observed for I. budapest M 20, I. "icterohaemorrhagiae" Ictero I and the type strain, I. icterohaemorrhagiae RGA. Clinical isolates and a isolate from a rat were compared with reference strain DNA patterns and identified as being similar to I. copenhageni M 20, I. "icterohaemorrhagiae" Ictero I and I. icterohaemorrhagiae RGA. These results indicate that ribosomal DNA fingerprinting may be useful in the classification and molecular epidemiology of pathogenic leptospires. AD - Leptospira Reference Laboratory, FAO/WHO Collaborating Centre, County Hospital, Hereford, U.K. PMID- 1982104 CU - 94 SO - FEMS Microbiol Lett 1990 Nov;60(3):329-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [211 medline neighbors] UI - 91072617 AU - Whipple D AU - Kapke P AU - Vary C TI - Identification of restriction fragment length polymorphisms in DNA from Mycobacterium paratuberculosis. LA - Eng MH - Animal MH - Cattle MH - DNA Probes MH - DNA, Bacterial/*genetics MH - Mycobacterium/*genetics/isolation & purification MH - Nucleic Acid Hybridization MH - Paratuberculosis/microbiology MH - Polymorphism, Restriction Fragment Length RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 910124 DP - 1990 Nov IS - 0095-1137 TA - J Clin Microbiol PG - 2561-4 SB - M CY - UNITED STATES IP - 11 VI - 28 JC - HSH AA - Author EM - 9103 AB - DNAs from 34 mycobactin-dependent isolates of Mycobacterium paratuberculosis and 1 isolate of M. paratuberculosis 18 were digested with four restriction endonucleases. Southern hybridization experiments were performed with a 32P-labeled oligonucleotide DNA probe derived from the sequence of IS900, an insertion sequence present in 15 to 20 copies per M. paratuberculosis chromosome. The probe hybridized with DNA from each of the mycobactin-dependent isolates, and restriction fragment length polymorphisms were detected among the isolates with each restriction endonuclease used. Restriction fragment length polymorphism analysis may permit identification of various strains of M. paratuberculosis, which has not been possible with other techniques. AD - Leptospirosis/Mycobacteriosis Research Unit, U.S. Department of Agriculture, Ames, Iowa 50010. PMID- 1979332 CU - 94 SO - J Clin Microbiol 1990 Nov;28(11):2561-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 91124654 AU - Isogai E AU - Isogai H AU - Fujii N AU - Oguma K TI - Biological effects of leptospiral lipopolysaccharide to mouse B, T and NK cells. LA - Eng MH - Animal MH - B-Lymphocytes/*immunology MH - Cells, Cultured MH - Cytotoxicity, Immunologic MH - Killer Cells, Natural/immunology MH - *Leptospira interrogans/classification MH - Lymphocyte Transformation MH - Male MH - Mice MH - *Mitogens MH - Polysaccharides, Bacterial/isolation & purification/*physiology MH - Serotyping MH - Spleen/cytology MH - T-Lymphocytes/*immunology RN - 0 (Mitogens) RN - 0 (Polysaccharides, Bacterial) PT - JOURNAL ARTICLE DA - 910311 DP - 1990 Oct IS - 0021-5295 TA - Nippon Juigaku Zasshi PG - 923-30 CY - JAPAN IP - 5 VI - 52 JC - KRJ AA - Author EM - 9105 AB - Leptospiral lipopolysaccharides (LPSs) extracted from Leptospira interrogans serovars copenhageni and hebdomadis were tested for the biological effect to mouse B, T and NK cells. Each leptospiral LPS was a potent mitogen for spleen B cells. Activation of the cells was also expressed by polyclonal B cell activation. In contrast, mitogenicity for T cells, induction of interleukin-2 (IL-2) secretion in T cells and increase of tumor-killing activity and chemiluminescence in NK cells were not observed after stimulation with leptospiral LPS. After intravenous injection of leptospiral LPS in mice, the spleen and lymphnodes were examined by histocytochemical technique. Increase of Ig- bearing lymphocytes was recognized while decrease of T cells was observed in the lymphoid organs. Mitogenic response to PHA, Con A and PWM decreased with relation to the T cell depletion. In conclusion, it is apparent that leptospiral LPS possess marked immunological potencies on B cells but not T and NK cells. The biological effects of leptospiral LPS were common ones as LPS but the level was considered to be different from classical LPS such as Escherichia coli LPS. AD - Department of Preventive Dentistry, School of Dentistry, Higashi Nippon Gakuen University, Hokkaido, Japan. PMID- 2280502 CU - 92 SO - Nippon Juigaku Zasshi 1990 Oct;52(5):923-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 91083814 AU - Cacciapuoti B AU - Ciceroni L AU - Barbini DA TI - Fatty acid profiles in the family Leptospiraceae. LA - Eng MH - Chromatography, Gas MH - Esters MH - Fatty Acids/*analysis MH - Leptospira/*analysis/classification MH - Leptospira canicola/analysis/classification MH - Leptospira interrogans/analysis/classification MH - Regression Analysis MH - Spirochaetaceae/*analysis/classification RN - 0 (Esters) RN - 0 (Fatty Acids) PT - JOURNAL ARTICLE DA - 910204 DP - 1990 Oct IS - 0934-8840 TA - Zentralbl Bakteriol PG - 16-27 SB - M CY - GERMANY IP - 1 VI - 274 JC - BD7 AA - Author EM - 9104 AB - Fatty acid profiles of six leptospira strains representative of genera, species, and serogroups within the family Leptospiraceae were determined by gas liquid chromatography (GLC) of fatty acid methyl ester (FAME) derivatives. The influence of methodological and biological variables on FAME profiles of the same strain was tested. FAME profiles were sharply affected by the fatty acid composition of the culture medium but not by the growth phase. Twenty-four FAME peaks were selected on the basis of their presence in repeated gas chromatographic runs of single strains. Inter-strain divergences of FAME profiles were quantified by linear regression analysis (LR). Step- wise divergences in FAME profiles were observed between strains at serogroup, species, and genus levels. AD - Department of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, Rome, Italy. RO - M:CNR PMID- 2261064 LR - 970218 CU - 92 SO - Zentralbl Bakteriol 1990 Oct;274(1):16-27 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 91083811 AU - Masuzawa T AU - Nakamura R AU - Shimizu T AU - Yanagihara Y TI - Biological activities and endotoxic activities of protective antigens (PAgs) of Leptospira interrogans. LA - Eng MH - Animal MH - Antigens, Bacterial/*toxicity MH - Biological Assay MH - Cell Line MH - Cells, Cultured MH - Cytotoxins/toxicity MH - Endotoxins/*toxicity MH - Leptospira interrogans/*immunology MH - Limulus Test MH - Mice MH - Mice, Inbred C3H MH - Mitogens/toxicity MH - Rabbits MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (Cytotoxins) RN - 0 (Endotoxins) RN - 0 (Mitogens) PT - JOURNAL ARTICLE DA - 910204 DP - 1990 Oct IS - 0934-8840 TA - Zentralbl Bakteriol PG - 109-17 SB - M CY - GERMANY IP - 1 VI - 274 JC - BD7 AA - Author EM - 9104 AB - The biological and endotoxic activities of protective antigens (PAgs) prepared by the chloroform-methanol-water method from Leptospira interrogans serovars lai, copenhageni and canicola were examined. The PAg preparations did not show a local Shwartzman reaction in the rabbits at doses of 100 micrograms and 50 micrograms/site and lethal toxicity to galactosamine-sensitized mice at the dose of 12.5 micrograms to 50 micrograms/mouse. PAgs exhibited a weak cytotoxic action on peritoneal exudate macrophages of C3H/HeJ and C3H/HeN mice at the dose of 500 micrograms/ml in vitro, but did not show cytotoxicity for BHK-21 cells kidney cells of the Syrian hamster, CHO-K1, ovary cells of the Chinese hamster, and CHL, lung cells of the Chinese hamster, at doses of 5 and 500 micrograms/ml. Gelation activity in the Limulus test was only observed at PAg concentrations over 100 ng/ml, which dose was 10,000 times that of lipopolysaccharide (LPS) of Escherichia coli O55:B5. Furthermore, an adjuvant activity of PAgs was not observed in the production of anti-sheep red blood cell antibody in mice. Mitotic conversion of spleen cells from C3H/HeJ and C3H/HeN mice was observed by the addition of PAgs in vitro. These results indicated that the biological properties of PAgs were different from those of LPS prepared from gram-negative enterobacteria, that PAgs had no endotoxic activity and that the biological safety of PAgs as vaccine was proved. AD - Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka, Japan. RO - M:CNR PMID- 2261063 LR - 970218 CU - 92 SO - Zentralbl Bakteriol 1990 Oct;274(1):109-17 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 91021638 AU - Staak C AU - Mekaprateep M AU - Kampe U AU - Schonberg A TI - Serological reactions of leptospirosis-positive (MAR and CFT) bovine sera in ELISA. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*blood MH - Cattle MH - Cattle Diseases/*diagnosis MH - Complement Fixation Tests MH - Enzyme-Linked Immunosorbent Assay MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 901107 DP - 1990 Oct IS - 0931-1793 TA - Zentralbl Veterinarmed [B] PG - 581-6 CY - GERMANY IP - 8 VI - 37 JC - Y72 AA - Author EM - 9101 AB - The collection of test sera for measuring ELISA results was composed of bovine sera with MAT titres of greater than or equal to 1:200 in the leptospirosis MAT and of greater than or equal to 1:5 in the CFT together with sera from a serologically negative and clinically non- suspicious cattle herd. To establish cut-off ODs, the geometric mean net-extinction of the negative serum collection plus 1, 2, and 3 standard deviations were calculated. By comparison of 3 different conjugates from rabbits, it was demonstrated that results from anti- total bovine Ig were superior to anti-IgG and anti-IgM conjugates. Considerations regarding sensitivity and specificity led to the recommendation to use a test serum dilution of 1:160, to apply anti- total bovine Ig conjugates, and to establish the cut-off OD at the geometric mean net-extinction of negative sera plus 3 standard deviations. Under such conditions, agreement between leptospirosis MAT/CFT positivity on the one side and ELISA positivity on the other was reached in 74%. This recommendation is made for cross-sectional studies but not for examinations of clinically suspicious cattle herds. AD - Institut fur Veterinarmedizin des Bundesgesundheitsamtes, Berlin. PMID- 2220193 CU - 91 SO - Zentralbl Veterinarmed [B] 1990 Oct;37(8):581-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [6 protein links] [1 nucleotide link] [202 medline neighbors] UI - 91009006 AU - Zuerner RL AU - Charon NW TI - Nucleotide sequence analysis of the Leptospira biflexa serovar patoc rpsL and rpsG genes. LA - Eng MH - Amino Acid Sequence MH - Bacterial Proteins/*genetics MH - Base Sequence MH - Comparative Study MH - *Genes, Bacterial MH - Leptospira/classification/*genetics MH - Molecular Sequence Data MH - Sequence Homology, Nucleic Acid MH - Serotyping MH - Support, U.S. Gov't, P.H.S. RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE ID - DE04645/DE/NIDR DA - 901114 DP - 1990 Oct IS - 0021-9193 TA - J Bacteriol PG - 6165-8 SB - M CY - UNITED STATES IP - 10 VI - 172 JC - HH3 AA - Author EM - 9101 AB - The Leptospira biflexa rpsL and rpsG genes were sequenced. Although similar in many respects, proteins encoded by these L. biflexa genes had several unusual features when compared with homologous proteins of other organisms. Unlike the rpsL genes of other eubacteria, the L. biflexa rpsL gene is adjacent to a rpoC-like gene. AD - Department of Microbiology and Immunology, School of Medicine, West Virginia University, Morgantown 26506. PMID- 2211535 CU - 93 SI - GENBANK/M30695 SI - GENBANK/M57776 SO - J Bacteriol 1990 Oct;172(10):6165-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 92159478 AU - da Silva MV AU - Batista L AU - Camargo ED AU - Leitao PA AU - Szalkay VG AU - Rosenthal C AU - Vaz AJ AU - de Souza AM TI - [Leptospirosis in patients with anti-HIV antibodies: report of 2 cases] LA - Por MH - Adult MH - Case Report MH - English Abstract MH - Human MH - HIV Antibodies/analysis MH - HIV Seropositivity/*complications MH - Leptospirosis/*complications MH - Male RN - 0 (HIV Antibodies) PT - JOURNAL ARTICLE DA - 920323 DP - 1990 Oct-Dec IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 229-31 CY - BRAZIL IP - 4 VI - 23 JC - RET AA - Author EM - 9205 AB - Two patients with concomitant leptospirosis and the acquired immunodeficiency syndrome (AIDS) are reported. In these cases different clinical aspects that can be attributed to simultaneity of these pathologies was not observed. AD - Hospital Emilio Ribas e Instituto Adolfo Lutz, Sao Paulo, Brasil. PMID- 2133590 TT - Leptospirose em doentes com anticorpos anti-HIV: relato de dois casos. EA - A SO - Rev Soc Bras Med Trop 1990 Oct-Dec;23(4):229-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 92071899 AU - D'Souza C AU - Dwivedi S AU - Balasubramanian R TI - Leptospirosis with atrial flutter (a case report). LA - Eng MH - Aged MH - Atrial Flutter/*diagnosis/etiology/physiopathology MH - Case Report MH - Electrocardiography MH - Human MH - India/epidemiology MH - *Leptospira canicola MH - Leptospirosis/*complications/diagnosis/epidemiology MH - Male PT - JOURNAL ARTICLE DA - 920107 DP - 1990 Oct IS - 0022-3859 TA - J Postgrad Med PG - 222-4 CY - INDIA IP - 4 VI - 36 JC - JS7 EM - 9203 AD - Department of Medicine, Kasturba Medical College, Manipal, Karnataka. PMID- 2132249 SO - J Postgrad Med 1990 Oct;36(4):222-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 91249008 AU - Trueba GA AU - Bolin CA AU - Thoen CO TI - Evaluation of an enzyme immunoassay for diagnosis of bovine leptospirosis caused by Leptospira interrogans serovar hardjo type hardjo-bovis. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*blood MH - Antigens, Bacterial/diagnostic use MH - Bacterial Vaccines/immunology MH - Cattle MH - Cattle Diseases/*diagnosis MH - Comparative Study MH - Cross Reactions MH - Evaluation Studies MH - IgM/analysis MH - *Immunoenzyme Techniques MH - Leptospira interrogans/*immunology MH - Predictive Value of Tests MH - Vaccination/veterinary MH - Weil's Disease/diagnosis/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 910709 DP - 1990 Oct IS - 1040-6387 TA - J Vet Diagn Invest PG - 323-9 SB - M CY - UNITED STATES IP - 4 VI - 2 JC - A2D AA - Author EM - 9109 AB - Sensitivity and specificity of 4 different antigen preparations from Leptospira interrogans serovar hardjo were compared in an enzyme immunoassay for detection of antibodies against serovar hardjo type hardjo-bovis in serum. Two antigens prepared using detergents showed serogroup cross-reactivity. A mechanically extracted membrane and a lipopolysaccharide antigen showed a high degree of leptospiral serogroup specificity. The lipopolysaccharide antigen was the most suitable antigen for detection of anti-hardjo antibodies. Enzyme immunoassay was more sensitive than the microscopic agglutination test for detecting antibodies in serum from experimentally and naturally infected cattle. It was not possible to differentiate vaccinated from infected animals or to detect a secondary immune response in vaccinated animals that were subsequently infected. AD - National Animal Disease Center, USDA, Ames, IA 50010. PMID- 2095282 CU - 91 SO - J Vet Diagn Invest 1990 Oct;2(4):323-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 91248999 AU - Thurmond MC AU - Picanso JP AU - Hietala SK TI - Prospective serology and analysis in diagnosis of dairy cow abortion. LA - Eng MH - Abortion, Veterinary/*diagnosis MH - Animal MH - Antibodies, Bacterial/*blood MH - Antibodies, Viral/*blood MH - Cattle MH - Cattle Diseases/*diagnosis MH - Diarrhea Virus, Bovine Viral/immunology MH - Female MH - Fetal Death/diagnosis/veterinary MH - Herpesvirus 1, Bovine/immunology MH - Leptospira/immunology MH - Multivariate Analysis MH - Pregnancy MH - Prospective Studies MH - Regression Analysis MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 910709 DP - 1990 Oct IS - 1040-6387 TA - J Vet Diagn Invest PG - 274-82 SB - M CY - UNITED STATES IP - 4 VI - 2 JC - A2D AA - Author EM - 9109 AB - A prospective serologic investigation was undertaken on 3 California dairies (herds 1, 3, and 4, as previously designated in a report on abortion surveillance) to determine if fetal loss was associated with infectious disease agents in cows. The diagnostic problem in these herds was typical of many dairies in that abortions were not discovered for several months and aborted fetuses were seldom recovered. Blood from approximately 100 pregnant cows in each herd was sampled at monthly intervals, beginning when the cows were palpated at approximately 40 days gestation. Sera were tested for antibodies to infectious bovine rhinotracheitis virus and bovine viral diarrhea virus (BVDV) and to the Leptospira serovars pomona, hardjo, grippotyphosa, icterohemorrhagiae, canicola, and szwajizak. Logn antibody titers were examined for an association with fetal loss, using multivariate methods of logistic regression and survival analysis. Of the 325 cows followed, 37 aborted, and no fetuses were recovered. Statistical analyses indicated that significant fetal loss was associated with high titers to L. hardjo and with low titers to L. szwajizak (herds 1 and 4) and BVDV (herd 1). Results for herd 3 revealed a connection between abortion and L. icterohemorrhagiae (P = 0.036) and L. canicola (P = 0.050) and possible vaccinal protection against abortion caused by L. grippotyphosa (P = 0.027 and 0.015). For herd 4, there was a marginally significant tendency for the first vaccination of the gestation against leptospirosis to have protected against fetal death (P = 0.077). Advantages of the diagnostic design were that it permitted comparison of titers of aborted cows with those of nonaborted cows and it considered vaccination-induced titers in analyses.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Medicine, Veterinary Medicine Teaching and Research Center, Tulare, CA 93274. PMID- 1965632 CU - 93 SO - J Vet Diagn Invest 1990 Oct;2(4):274-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 91132109 AU - Ballard SA AU - Faine S AU - Adler B TI - Purification and characterization of a protein antigen from Leptospira interrogans serovar hardjo, common to a wide range of bacteria. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Bacterial Proteins/chemistry/metabolism MH - Cattle MH - Cross Reactions MH - Leptospira interrogans/*immunology MH - Molecular Weight MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE DA - 910318 DP - 1990 Sep IS - 0022-1287 TA - J Gen Microbiol PG - 1849-57 SB - M CY - ENGLAND VI - 136 ( Pt 9) JC - I87 AA - Author EM - 9105 AB - A protein with a molecular mass of 64 kDa (P64) from Leptospira interrogans serovar hardjo was partially purified by using successively, phase partitioning with Triton X-114, ion-exchange chromatography and sucrose gradient centrifugation. Purification to homogeneity was obtained by electroelution of P64 from SDS- polyacrylamide gels. Monospecific rabbit antiserum (R alpha P64) was prepared using the purified protein preparation. P64 had a native molecular mass of greater than 670 kDa and was recognized by R alpha P64 as well as by human antisera. Western blotting of leptospiral serovars and 18 other bacterial species with R alpha P64 showed that P64 was cross-reactive with an equivalent antigen in a wide range of bacteria, indicating that it belongs to a family of antigens previously designated 'common antigen'. This putative common antigen from Leptospira appears to have a sub-surface location, but its function is not yet known. AD - Department of Microbiology, Monash University, Melbourne, Victoria, Australia. PMID- 2283504 CU - 91 SO - J Gen Microbiol 1990 Sep;136 ( Pt 9):1849-57 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 91115073 AU - Baril C AU - Saint Girons I TI - Sizing of the Leptospira genome by pulsed-field agarose gel electrophoresis. LA - Eng MH - *Chromosomes, Bacterial MH - Deoxyribonucleases, Type II Site-Specific MH - Electrophoresis, Agar Gel MH - *Genes, Bacterial MH - Leptospira/*genetics MH - Leptospira interrogans/*genetics MH - Support, Non-U.S. Gov't RN - EC 3.1.21.- (endodeoxyribonuclease ApaI) RN - EC 3.1.21.- (endodeoxyribonuclease NheI) RN - EC 3.1.21.- (endodeoxyribonuclease NotI) RN - EC 3.1.21.4 (Deoxyribonucleases, Type II Site-Specific) PT - JOURNAL ARTICLE DA - 910307 DP - 1990 Sep 1 IS - 0378-1097 TA - FEMS Microbiol Lett PG - 95-9 SB - M CY - NETHERLANDS IP - 1-2 VI - 59 JC - FML AA - Author EM - 9105 AB - Pulsed-field gel electrophoresis allowed the determination of the size of the genome of Leptospira, a bacterium of the spirochete family. The three restriction enzymes, NotI (5'GC/GGCCGC), NheI (5'G/CTAGC), ApaI (5'-GGGCC/C) generated DNA fragments of suitable size. The results are compatible with a size of 5000 kb for the chromosome of both the pathogenic and the saprophytic species of Leptospira. AD - Unite des Leptospires, Institut Pasteur, Paris, France. PMID- 2276619 SO - FEMS Microbiol Lett 1990 Sep 1;59(1-2):95-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 91086021 AU - Corwin A AU - Ryan A AU - Bloys W AU - Thomas R AU - Deniega B AU - Watts D TI - A waterborne outbreak of leptospirosis among United States military personnel in Okinawa, Japan. LA - Eng MH - Adult MH - *Disease Outbreaks MH - Human MH - Japan/epidemiology MH - *Leptospira interrogans MH - Leptospirosis/*epidemiology/microbiology MH - Male MH - *Military Personnel MH - Space-Time Clustering MH - Support, U.S. Gov't, Non-P.H.S. MH - Swimming MH - United States MH - *Water Microbiology MH - Weather MH - Weil's Disease/epidemiology/microbiology PT - JOURNAL ARTICLE DA - 910201 DP - 1990 Sep IS - 0300-5771 TA - Int J Epidemiol PG - 743-8 SB - M CY - ENGLAND IP - 3 VI - 19 JC - GR6 AA - Author EM - 9104 AB - A waterborne outbreak of leptospirosis occurred among US military personnel during September 1987, on the island of Okinawa, Japan. Micro- agglutination titres for leptospiral antigen of greater than or equal to 200 were detected in hospitalized adult males averaging 22.5 years of age with symptoms compatible with leptospirosis. Epidemiological findings revealed two case clusters distinguished by time and place of exposure. The overall attack rates among recreational swimmers and combat skills training participants were 467/1000 (7/15) and 183/1000 (15/82), respectively. Swallowing of water differentiated individuals with laboratory-confirmed infection from those with no infection, while water immersion alone did not appear to result in leptospiral infection. Additionally, subnormal rainfall may have contributed to the risk of exposure associated with this outbreak. AD - Division Surgeon's Office, 3rd Marine Division, Okinawa, Japan. PMID- 2262273 SO - Int J Epidemiol 1990 Sep;19(3):743-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 91077156 AU - Chapman AJ AU - Faine S AU - Adler B TI - Antigens recognized by the human immune response to vaccination with a bivalent hardjo/pomona leptospiral vaccine. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Bacterial Vaccines/*immunology MH - Comparative Study MH - Hamsters MH - Human MH - Immunity, Natural MH - Immunization, Passive MH - Immunoblotting MH - Immunoenzyme Techniques MH - Leptospira interrogans/classification/*immunology MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 910129 DP - 1990 Sep IS - 0920-8534 TA - FEMS Microbiol Immunol PG - 111-8 SB - M CY - NETHERLANDS IP - 2 VI - 2 JC - AO3 AA - Author EM - 9104 AB - Serum from volunteer subjects vaccinated with a bivalent whole cell vaccine of Leptospira interrogans serovar hardjo/serovar pomona grown in protein-free medium, was tested by the microscopic agglutination test (MAT), enzyme-immunoassay (EIA) and immunoblotting. Specific IgM antibodies to either serovars hardjo or pomona were detected in some subjects as early as 6 days after vaccination with peak antibody levels occurring 13-68 days after vaccination. Whereas all subjects produced specific IgM to both serovars, not all produced specific IgG to both serovars. Immunoblotting with hardjo sonicate revealed that all subjects produced IgM antibodies reacting with the 15, 23 and 28 kDa components of hardjo lipopolysaccharide (LPS), and most produced IgM antibodies that reacted with the 34.5 kDa flagellar doublet. In contrast, not all sera immunoblotted against pomona sonicate reacted with the 29 and 35 kDa components of pomona LPS. However all subjects produced antibodies reacting with a diffuse 14.4-27 kDa band. These antibodies appeared early in the immune response. Serum from the one vaccinated subject tested protected hamsters from acute lethal infection with serovar pomona. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 2257162 CU - 91 SO - FEMS Microbiol Immunol 1990 Sep;2(2):111-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 91075852 AU - Makeev SM AU - Maramovich AS AU - Iaroshenko VA TI - [Immunologic monitoring of leptospirosis in the Maritime Territory] LA - Rus MH - Animal MH - Animals, Domestic MH - Animals, Wild MH - Antibodies, Bacterial/blood MH - Disease Outbreaks MH - Disease Vectors MH - English Abstract MH - Horses MH - Human MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*epidemiology/immunology/microbiology/transmission/veterin ary MH - Monitoring, Immunologic MH - Seroepidemiologic Methods MH - Siberia/epidemiology MH - Swine RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910124 DP - 1990 Sep IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 31-6 SB - M CY - USSR IP - 9 JC - Y9O AA - Author EM - 9103 AB - The epidemiological and epizootic situation in Leptospira infections at the Maritime [correction of Primorski] Territory is evaluated on the basis of complex studies carried out in 1984-1989. As revealed in these studies, cases of leptospirosis among humans have a sporadic character and are mainly registered among professional high risk groups of the population. In the immunological structure of persons covered by the survey L. hebdomadis, L. pomona and L. javanica prevail. The anthropourgic foci of leptospirosis caused by L. pomona are of the leading epidemiological importance. Swine serves as the main source of infection in these foci. The study revealed the epidemic danger of the natural foci of leptospirosis caused by L. grippotyphosa and L. javanica in rice fields where the decisive factors of leptospirosis proved to be reed voles and striped field mice serving as reservoirs of this infection, as well as the synanthropic foci of leptospirosis caused by L. hebdomadis with house mice serving as the main carriers. PMID- 2256398 CU - 91 TT - Immunologicheskii monitoring leptospirozov v Primorskom krae. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1990 Sep;(9):31-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 91047260 AU - Ramadass P AU - Marshall RB AU - Jarvis BD TI - Species differentiation of Leptospira interrogans serovar hardjo strain Hardjobovis from strain Hardjoprajitno by DNA slot blot hybridisation. LA - Eng MH - Animal MH - Comparative Study MH - DNA Probes MH - DNA, Bacterial/*analysis MH - Genotype MH - Leptospira interrogans/*classification/genetics MH - Nucleic Acid Hybridization MH - Restriction Mapping MH - Support, Non-U.S. Gov't RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 901204 DP - 1990 Sep IS - 0034-5288 TA - Res Vet Sci PG - 194-7 SB - M CY - ENGLAND IP - 2 VI - 49 JC - R7D AA - Author EM - 9102 AB - Slot blot hybridisation studies with total genomic DNA probes were used to compare Leptospira interrogans serovar hardjo strain Hardjoprajitno, strain Hardjobovis and a number of other Leptospira interrogans serovars. Strains Hardjoprajitno and Hardjobovis were found to have little genetic relationship with each other when compared to some of the other serovars tested. Hardjoprajitno is closely related to serovar icterohaemorrhagiae and not to Hardjobovis whereas Hardjobovis is closely related to serovars vietnam, balcanica and javanica but not to serovar icterohaemorrhagiae; this places strain Hardjoprajitno in the species L interrogans and strain Hardjobovis in the species L borgpetersoni. Because of this lack of genetic relatedness between strains Hardjoprajitno and Hardjobovis, it is proposed to remove the prefix Hardjo from the strain name Hardjobovis and call it L borgpetersoni serovar hardjo strain Bovis. AD - Department of Veterinary Pathology and Public Health, Massey University, Palmerston North, New Zealand. PMID- 2236916 CU - 92 SO - Res Vet Sci 1990 Sep;49(2):194-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 91036021 AU - Cinco M TI - Evaluation of monoclonal antibody F9-4 as immunological probe for Leptospira interrogans. LA - Eng MH - *Antibodies, Bacterial MH - *Antibodies, Monoclonal MH - Biological Markers MH - Comparative Study MH - Evaluation Studies MH - Human MH - Leptospira interrogans/classification/*immunology/pathogenicity MH - Species Specificity MH - Virulence/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Biological Markers) PT - JOURNAL ARTICLE DA - 901213 DP - 1990 Sep IS - 0095-1137 TA - J Clin Microbiol PG - 2154-5 SB - M CY - UNITED STATES IP - 9 VI - 28 JC - HSH AA - Author EM - 9102 AB - I assayed the lack of reactivity of monoclonal antibody (MAb) F9-4 with nonpathogenic leptospires. Of 47 saprophytic strains tested, 46 did not react in an enzyme immunoassay and 1 was recognized by MAb F9-4, as usually reported with pathogenic Leptospira strains. On the other hand, the MAb did not react with one pathogenic strain, thus showing that the ability of MAb F9-4 to discriminate between pathogenic and nonpathogenic leptospires is not absolute. AD - Istituto di Microbiologia, Universita di Trieste, Italy. PMID- 2229401 CU - 92 SO - J Clin Microbiol 1990 Sep;28(9):2154-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 91244250 AU - Xiao J AU - Dai B AU - Chai J AU - Yu L TI - [The study on genome size of leptospires] LA - Chi MH - Cloning, Molecular MH - DNA, Bacterial/analysis MH - Electrophoresis, Agar Gel/methods MH - English Abstract MH - Genes, Bacterial/*genetics MH - Leptospira/*genetics MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 910628 DP - 1990 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 362-5 CY - CHINA IP - 4 VI - 21 JC - GEB AA - Author EM - 9109 AB - Determination of genome size is very important in genetic studies and the molecular cloning of leptospires. With pulsed field gel electrophoresis (PFGE), which can be used in the analysis of large DNA molecules, we studied the genome size of leptospires and analysed it with rare cutter restrict endonuclease Not I. The PFGE system used was CHEF-DR II which produced parallel bands in agarose gel. The results showed that the genome size of leptospires was 2000kb and there was no dramatic difference between the 5 strains of 2 genus leptospira. Rare cutter Not I digestion of genome DNA of leptospira resulted in 11 bands and its bands pattern was quite different from that of E. coli, S. choleraesuis, S. typhimurium, and S. dysenteriae genome DNA. It is thought that more information can be obtained about leptospiral DNA with PFGE technique. AD - Research Unit of Leptospirosis, Institute of Genetics, Fudan University. PMID- 2094631 CU - 91 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1990 Sep;21(4):362-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 91244249 AU - Bao L AU - Dai B AU - Terpstra WK AU - Van Eys GJ TI - [DNA hybridization and identification of Leptospira serogroup icterohaemorrhagiae with Leptospira recombinant DNA probes] LA - Chi MH - Blotting, Southern MH - Cloning, Molecular MH - DNA Probes MH - DNA, Bacterial/*analysis MH - English Abstract MH - Leptospira interrogans/genetics/*isolation & purification MH - Nucleic Acid Hybridization MH - Support, Non-U.S. Gov't RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 910628 DP - 1990 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 357-61 CY - CHINA IP - 4 VI - 21 JC - GEB AA - Author EM - 9109 AB - Two recombinant DNA probes-PLIpso1 (15kb) and PLIEc34 (4kb), derived from Leptospira serovaricterohaemorrhagiae genomic libraries, were applied for the hybridization and identification of 13 strains of Leptospira in serogroup icterohaemorrhagiae. Difference in hybridization signal in combination with the banding pattern provide a good way for identification of serovars and strains. The recombinant DNA, specific to L. serogroup icterohaemorrhagiae, hybridized with a limited number of DNA fragments which had been digested by several restriction endonucleases. The less complex banding pattern and higher sensitivity facilitate characterization of various serovars and strains in serogroup icterohaemorrhagiae. In general the DNA patterns recognized by both probes have extensive genomic homology in same serovar (but still can distinguish strains in same serovar by some unique bands) and apparent difference in various serovars (especially serovars naam, nanxi and honghe). The results indicated that Southern blotting with recombinant DNA probe might provide tools for identification, characterization and analysis of leptospira. AD - WHO/FAO Collaborating Centre for Reference and Research on Leptospirosis, Royal Tropical Institute, Amsterdam, The Netherlands. PMID- 2094630 CU - 92 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1990 Sep;21(4):357-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 91231296 AU - Zhao H AU - Li S AU - Yan R AU - Dai B TI - [Investigation on the immunoprotection of monoclonal antibodies against outer envelopes of serogroup Icterohaemorrhagiae serovar lai strain 017 leptospires] LA - Chi MH - Animal MH - Antibodies, Monoclonal/*immunology/therapeutic use MH - Bacterial Outer Membrane Proteins/*immunology MH - English Abstract MH - Female MH - Guinea Pigs MH - Immunization, Passive MH - Leptospira interrogans/classification/*immunology MH - Male MH - Mice MH - Mice, Inbred BALB C MH - Serotyping MH - Support, Non-U.S. Gov't MH - Weil's Disease/*prevention & control RN - 0 (Antibodies, Monoclonal) RN - 0 (Bacterial Outer Membrane Proteins) PT - JOURNAL ARTICLE DA - 910619 DP - 1990 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 239-41 CY - CHINA IP - 3 VI - 21 JC - GEB AA - Author EM - 9108 AB - BALB/c mice were immunized intraperitoneally with outer envelopes of serogroup icterohaemorrhagiae lai serovar strain 017 leptospires. Monoclonal antibodies against outer envelopes (IgG, agglutinating titre 1:25,600) were produced by hybridoma technique. The monoclonal antibodies ascites (diluted 1:100) 1 ml administered intraperitoneally 1 hour before the intraperitoneal injection of 2 x 10(8) leptospires of strain 017 and the subsequent daily administration of McAb in similar doses for five days protected 80% of guinea pigs. Survival rates of three control groups which received physiological saline, ascites of BALB/c mouse myeloma cell lines SP2/0, and monoclonal antibodies against Pseudomonas aeruginosa in place of monoclonal antibodies against outer envelopes of strain 017 leptospires were 10%, 20% and 10% respectively. When killed 20 days after challenge, guinea pigs of experiment group were normal at autopsy. Old pulmonary haemorrhage were present in the animals of three control groups. Passive immunoprotection experiments have demonstrated immunoprotection of monoclonal antibodies against outer envelopes of strain 017 leptospires. It will be valuable for separating protective antigen fraction of outer envelopes and studying new vaccine of leptospira. PMID- 2093058 CU - 91 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1990 Sep;21(3):239-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 91231294 AU - Xiao J AU - Dai B TI - [The study on homology of leptospires with molecular hybridization] LA - Chi MH - DNA Probes MH - DNA, Bacterial/*analysis MH - English Abstract MH - Human MH - Leptospira interrogans/classification/*genetics MH - Nucleic Acid Hybridization MH - Sequence Alignment MH - Support, Non-U.S. Gov't RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 910619 DP - 1990 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 230-3 CY - CHINA IP - 3 VI - 21 JC - GEB AA - Author EM - 9108 AB - Homology of leptospires from different genus, different serogroups were studied with molecular hybridization. Leptospiral DNAs were extracted and purified with phenolchloroform-isoamylalcohol method. Alpha 32P- dCTP was used to label DNA from L. interrogans serogroup icterohaemorrhagiae serovar lai strain 017 as a DNA probe, and hybridized with DNAs of 2 genus, 5 serogroups of leptospires represented by 6 strains on NC filter. Four serogroups of pathogenic leptospires which caused endemic disease in Sichuan Province were also detected by the probe. The results showed that L. interrogans serogroup icterohaemorrhagiae, serogroup autumnalis and serogroup hebdomadis had a high degree of homology while there was a low degree of homology between L. interrogans and L. biflexa and Leptonema illini. Four major serogroups of pathogenic leptospires in Sichuan Province, with their high degree of homology, could be detected by a radiolabelled probe from serogroup icterohaemorrhagiae. Hybridization may be used as a tool for diagnosis of leptospirosis in human beings and animals. PMID- 2093057 CU - 92 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1990 Sep;21(3):230-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 91231293 AU - Bao L AU - Dai B TI - [Detection of the microquantity DNA of Leptospira interrogans by polymerase chain reaction] LA - Chi MH - Animal MH - Cloning, Molecular MH - Comparative Study MH - DNA, Bacterial/*analysis MH - DNA, Recombinant MH - English Abstract MH - Human MH - Leptospira interrogans/*isolation & purification MH - Oligonucleotides MH - Polymerase Chain Reaction MH - Support, Non-U.S. Gov't MH - Weil's Disease/diagnosis RN - 0 (DNA, Bacterial) RN - 0 (DNA, Recombinant) RN - 0 (Oligonucleotides) PT - JOURNAL ARTICLE DA - 910619 DP - 1990 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 225-9 CY - CHINA IP - 3 VI - 21 JC - GEB AA - Author EM - 9108 AB - Leptospirosis is a severe zoonosis in the world. The methods for detecting leptospira are not sensitive and specific so far. The problems in early diagnosis and epidemiological identification of Leptospirosis remain unsolved. Two recombinant DNA fragments of serogroup Icterohaemorrhagiae, Leptospira were selected by repeated molecular cloning and screening in this study firstly. One of them can hybridize with the DNA of various serogroups of Leptospira interrogans; the other can only hybridize with the DNA of serogroup Icterohaemorrhagiae. After the nucleotides sequence analysis, from these 2 recombinant DNA fragments, 2 pairs of polymerase chain reaction (PCR) oligonucleotide primers were synthesized, named primer B 1, 2 and primer B 3, 4 PCRs were carried out with these 2 primers for detecting the microquantity (0.1 ng) of various serovars, serogroup of leptospires. All the DNA of Leptospira interrogans can be amplified by primer B 1, 2, and only the DNA of serogroup icterohaemorrhagiae, Leptospira reacted specially with primer B 3, 4. The DNA of non- pathogenetic Leptospira and some other microbes, however, had no amplification at all. This study is first reported at home and abroad. The results demonstrate that PCR is a very sensitive and specific technique of DNA amplification, which can be used as a powerful tool in the early diagnosis and epidemiological identification of leptospirosis. PMID- 2093056 CU - 92 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1990 Sep;21(3):225-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 91082383 AU - Zuerner RL AU - Bolin CA TI - Nucleic acid probe characterizes Leptospira interrogans serovars by restriction fragment length polymorphisms. LA - Eng MH - Animal MH - Autoradiography MH - Blotting, Southern MH - *DNA Probes MH - DNA, Bacterial/*analysis MH - Electrophoresis, Agar Gel MH - Leptospira interrogans/*genetics MH - Nucleic Acid Hybridization MH - *Polymorphism, Restriction Fragment Length MH - Repetitive Sequences, Nucleic Acid MH - Restriction Mapping RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 910131 DP - 1990 Sep IS - 0378-1135 TA - Vet Microbiol PG - 355-66 SB - M CY - NETHERLANDS IP - 3-4 VI - 24 JC - XBW AA - Author EM - 9104 AB - Restriction endonuclease analysis (REA) of genomic DNA can discriminate between many Leptospira interrogans serovars. However, several serovars have similar restriction endonuclease digestion patterns which prohibits accurate identification. This investigation expands previous REA studies of L. interrogans to include serovars in serogroup Tarassovi. Most serovars in this serogroup had characteristic digestion patterns by which they could be identified. However, four of the serovars in this serogroup had similar digestion patterns, thus preventing serovar identification by REA alone. To discriminate between these serovars REA was supplemented with Southern blot analysis. The DNA from each serovar showed similar but unique patterns when hybridized with a probe synthesized from a repetitive sequence element cloned from L. interrogans serovar hardjo type hardjo-bovis. The applicability of this technique to characterize other serogroups was assessed. One hundred sixty six of 190 serovars screened by Southern blot analysis contained sequences which hybridized with the repetitive element probe under conditions of relaxed stringency. These results suggest that Southern blot analysis using this probe will be a valuable supplement for typing L. interrogans. AD - U.S. Department of Agriculture, National Animal Disease Center, Ames, IA 50010. PMID- 1979703 CU - 94 SO - Vet Microbiol 1990 Sep;24(3-4):355-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 91231295 AU - Liang J AU - Dai B TI - [Study on the production, identification of serogroup-specific monoclonal antibodies against leptospires of Australis serogroup and detection of its antigen] LA - Chi MH - Animal MH - Antibodies, Monoclonal/*biosynthesis MH - Antigens, Bacterial/*analysis MH - Bacterial Outer Membrane Proteins/immunology MH - English Abstract MH - Epitopes MH - Human MH - Leptospira interrogans/*classification/immunology MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 910619 DP - 1990 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 234-8 CY - CHINA IP - 3 VI - 21 JC - GEB AA - Author EM - 9108 AB - Spleen cells of BALB/c mice immunized with whole Leptospira interrogans serogroup Australis serovar australis strain 620 were fused with myeloma cells line SP2/0. Specificities of four McAbs determined by MAT. 2E1 McAb (IgG3) reacted with 11 serovars, of the Australis serogroup, but did not react with 22 representative serovars of L. interrogans in 20 serogroups, L. biflexa strain patoc I and Leptonema illini strain 3055. 2E1 McAb showed serogroup specificity for Australis by agglutination and the other 3 McAbs showed partial serogroup specificity. We compared the outer envelope (OE) protein profiles of serovar australis strain 620 with those of two pathogenic L. interrogans serovar lai strain 601 and serovar hebdomadis strain 156 by SDS-PAGE. 63kd protein profile was only found in the OE of strain 620, and the quantity of 42kd protein of strain 620 was greater than that of strain 601 and 156. The immunoblotting revealed that 2E1 McAb reacted with a 34kd band in the OE preparation of serovar australis strain 620, but did not react with that of other two L. interrogans. 2E1 McAb also did not react with OE of non-pathogenic leptospires. It was suggested that 34kd protein might contain the antigenic determinants which were shared by leptospires of Australis serogroup. PMID- 1709413 CU - 95 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1990 Sep;21(3):234-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 91071040 AU - Chen Y TI - [A clinicopathological analysis of 12 cases of cerebrovascular leptospirosis] LA - Chi MH - Adolescence MH - Arteritis/pathology MH - Cerebral Hemorrhage/pathology MH - Cerebral Infarction/pathology MH - Cerebrovascular Disorders/*pathology MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*pathology MH - Male PT - JOURNAL ARTICLE DA - 910124 DP - 1990 Aug IS - 0412-4057 TA - Chung Hua Shen Ching Ching Shen Ko Tsa Chih PG - 226-8, 255 CY - CHINA IP - 4 VI - 23 JC - D7Y AA - Author EM - 9103 AB - 12 pathologically verified cases of cerebrovascular leptospirosis were analysed of its clinical characteristics and types. Formation and development of cerebral panarteritis and infarctions were also discussed. It occurred in rural areas among children and adolescents after infection by leptospira pomona, especially following latent infection. Multiple occlusive vascular disorder presenting as a late manifestation of pomona infection occurred in 9 cases, intracranial hemorrhage in 2, and intracranial hypertension in 1 case. Cerebral panarteritis involved the main trunks of larger arteries at the base of the brain. Owing to invariable narrowing of intracranial portions of internal carotid arteries, infarcts always appeared in areas supplied by the middle cerebral artery, often accompanied by marginal infarction at watershed areas. It was suggested that cerebrovascular leptospirosis could be ascribed to residual infection of cerebral arteries soaked in CSF during the septicemic stage of pomona infection. AD - Nanjing Neuropsychiatric Institute. PMID- 2253511 EA - A SO - Chung Hua Shen Ching Ching Shen Ko Tsa Chih 1990 Aug;23(4):226-8, 255 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 91020606 AU - Johnachan PM AU - Smith GS AU - Grant G AU - Hugh-Jones ME TI - Serological survey for leptospiral antibodies in goats in St Elizabeth Parish, Jamaica, 1985-1986. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/blood/immunology MH - Goat Diseases/*diagnosis/epidemiology MH - Goats MH - Jamaica/epidemiology MH - Leptospira canicola/immunology MH - Leptospirosis/diagnosis/epidemiology/*veterinary MH - Prevalence MH - Seasons MH - Species Specificity MH - Support, Non-U.S. Gov't MH - Time Factors RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 901106 DP - 1990 Aug IS - 0049-4747 TA - Trop Anim Health Prod PG - 171-7 SB - M CY - SCOTLAND IP - 3 VI - 22 JC - WG2 AA - Author EM - 9101 AB - A serological survey of goats in St Elizabeth Parish, Jamaica, comprising the breeding herd at the Agricultural Development Corporation (ADC) facility at Hounslow, five commercial herds and 21 family herds was carried out in 1985-1986. The Leptospira microscopic agglutination test indicated that one or more serovars in the Canicola serogroup were the most prevalent. Repeated samplings of goats at ADC, Hounslow demonstrated an increase in portlandvere and canicola seropositive animals following the onset of warmer weather and of icterohaemorrhagiae seropositive animals following the autumn rains and cooler weather. Apart from a cluster of family goats seropositive to pomona there was no geographical separation of reactors to the other serovars tested in the parish. AD - Veterinary Division, Ministry of Agriculture, Santa Cruz, St Elizabeth, Jamaica. PMID- 2219456 CU - 91 SO - Trop Anim Health Prod 1990 Aug;22(3):171-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 91019114 AU - Bonard EC TI - [Jaundice. Clinical discussion] LA - Fre MH - Case Report MH - Cholestasis/*etiology MH - Diagnosis, Differential MH - Human MH - Leptospirosis/*complications/diagnosis MH - Liver Diseases/*complications/diagnosis MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 901102 DP - 1990 Aug IS - 0035-3655 TA - Rev Med Suisse Romande PG - 687-9 CY - SWITZERLAND IP - 8 VI - 110 JC - SR5 EM - 9101 PMID- 2218256 TT - Ictere. Dialogue clinique. SO - Rev Med Suisse Romande 1990 Aug;110(8):687-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 90324682 AU - Watt G AU - Padre LP AU - Tuazon M AU - Calubaquib C TI - Limulus lysate positivity and Herxheimer-like reactions in leptospirosis: a placebo-controlled study. LA - Eng MH - Adult MH - Bilirubin/blood MH - Creatinine/blood MH - Endotoxins/analysis MH - Female MH - Follow-Up Studies MH - Human MH - Leptospirosis/*drug therapy/immunology MH - Leukocyte Count MH - Limulus Test MH - Male MH - Penicillin G/adverse effects/*therapeutic use MH - Prospective Studies MH - Randomized Controlled Trials MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Endotoxins) RN - 60-27-5 (Creatinine) RN - 61-33-6 (Penicillin G) RN - 635-65-4 (Bilirubin) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - RANDOMIZED CONTROLLED TRIAL DA - 900827 DP - 1990 Aug IS - 0022-1899 TA - J Infect Dis PG - 564-7 SB - A SB - M CY - UNITED STATES IP - 2 VI - 162 JC - IH3 AA - Author EM - 9011 AB - Jarisch-Herxheimer reactions are characteristic of some spirochetal diseases and have been reported in leptospirosis, but their pathogenesis and relationship to endotoxin remain unclear. Serial limulus amebocyte lysate assays (LAL) for endotoxin were performed on 40 patients with proven leptospirosis who were monitored for reactions after receiving either intravenous penicillin (24) or saline placebo (16). No Herxheimer-like reactions were observed, although 78% of patients had at least one positive LAL. Serum creatinine, serum bilirubin, and white blood cell counts were significantly higher (P less than .01) in simultaneously drawn LAL-positive specimens than in negative ones. Delayed hepatic clearance of endotoxin due to liver dysfunction may explain the high LAL positivity rate, since assay results correlated with severity of disease but not with the presence or absence of spirochetes. Fear of a Herxheimer-like reaction should not dissuade clinicians from administering antibiotics to patients with leptospirosis. AD - Naval Medical Research Unit Number 2, APO San Francisco 96528. PMID- 2197347 CU - 91 SO - J Infect Dis 1990 Aug;162(2):564-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 91000127 AU - Gsell O TI - The changing epidemiology of leptospirosis in Europe. A report on the 6th meeting of European Leptospira workers, Brno, Czechoslovakia, September 1988. LA - Eng MH - Animal MH - Disease Outbreaks MH - Europe/epidemiology MH - Human MH - Incidence MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*epidemiology MH - Weil's Disease/*epidemiology PT - MEETING REPORT PT - REVIEW PT - REVIEW, TUTORIAL DA - 901114 DP - 1990 Aug IS - 0934-8840 TA - Zentralbl Bakteriol PG - 412-27 SB - M CY - GERMANY IP - 3 VI - 273 JC - BD7 EM - 9101 RF - 56 RO - M:CNR PMID- 1976307 LR - 970218 CU - 94 SO - Zentralbl Bakteriol 1990 Aug;273(3):412-27 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 90373745 AU - Ramadass P AU - Jarvis BD AU - Corner RJ AU - Cinco M AU - Marshall RB TI - DNA relatedness among strains of Leptospira biflexa. LA - Eng MH - *DNA, Bacterial MH - Leptospira/classification/*genetics MH - Nucleic Acid Hybridization MH - Phylogeny MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 901018 DP - 1990 Jul IS - 0020-7713 TA - Int J Syst Bacteriol PG - 231-5 SB - M CY - UNITED STATES IP - 3 VI - 40 JC - AWO AA - Author EM - 9012 AB - The slot blot method of DNA hybridization was used to study 38 strains of Leptospira biflexa belonging to 38 serovars. Fifteen of these serovars were placed into six groups. The remaining 23 serovars were generally too diverse to show significant DNA relatedness either to these groups or to one another. Serovar thracia was related to Group 5, but it was not included in this group because its percent relatedness was too low. We found that genetically related organisms were antigenically dissimilar. The absence of any significant genetic relationship between Leptonema illini and the Leptospira biflexa serovars tested supports the placement of the former species in a separate genus. AD - Department of Veterinary Pathology and Public Health, Faculty of Veterinary Science, Massey University, Palmerston North, New Zealand. PMID- 2397191 CU - 91 SO - Int J Syst Bacteriol 1990 Jul;40(3):231-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [49 medline neighbors] UI - 90311310 AU - Goldstein SF AU - Charon NW TI - Multiple-exposure photographic analysis of a motile spirochete. LA - Eng MH - *Cell Movement MH - Ficoll MH - Flagella/physiology/ultrastructure MH - Leptospira/cytology/*physiology MH - *Models, Biological MH - Photography MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. RN - 25702-74-3 (Ficoll) PT - JOURNAL ARTICLE ID - DEO4645 DA - 900815 DP - 1990 Jul IS - 0027-8424 TA - Proc Natl Acad Sci U S A PG - 4895-9 SB - M SB - X CY - UNITED STATES IP - 13 VI - 87 JC - PV3 AA - Author EM - 9010 AB - The Leptospiraceae are thin spirochetes with a unique mode of motility. These spiral-shaped bacteria have internal periplasmic flagella that propel the cells in low-viscosity and gel-like high-viscosity media. A model of Leptospiraceae motility has been previously proposed that states that the subterminally attached periplasmic flagella rotate between the outer sheath and the helical protoplasmic cylinder. The shape of the cell ends and the direction of gyration of these ends are determined by the direction of rotation of the internal periplasmic flagella. Rotation of the periplasmic flagella in one direction causes that end to be spiral-shaped, and rotation in the other direction causes that end to be hook-shaped. One prediction of the model is that these right-handed spirochetes roll clockwise when swimming away from an observer. For maximum swimming efficiency, the model predicts that the sense of the spiral-shaped end is left-handed and gyrates counterclockwise. The present study presents direct evidence that the cell rolls clockwise (protoplasmic cylinder helix diameter = 0.24 micron; pitch = 0.69 micron), the ends gyrate counterclockwise, and the spiral-shaped end is left-handed (helix diameter = 0.6 micron; pitch = 2.7 microns)--as predicted by the model. The hook-shaped end appears approximately planar. The approach used was to illuminate stroboscopically cells slowed by Ficoll and analyze the resultant multiple-exposure photographs focused above and below the axis of the cell. The methodology used should be helpful in analyzing the motility of the larger and more complex spirochetes. AD - Department of Genetics and Cell Biology, University of Minnesota, Saint Paul 55108. PMID- 2367518 CU - 95 SO - Proc Natl Acad Sci U S A 1990 Jul;87(13):4895-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 90285528 AU - Watt G AU - Padre LP AU - Tuazon M AU - Calubaquib C TI - Skeletal and cardiac muscle involvement in severe, late leptospirosis. LA - Eng MH - Acute Disease MH - Bilirubin/blood MH - Creatine Kinase/blood MH - Creatine Kinase Isoenzymes/blood MH - Creatinine/blood MH - Electrocardiography MH - Female MH - Heart Block/complications/pathology MH - Heart Diseases/*complications/pathology MH - Human MH - Leptospira/classification MH - Male MH - Muscles/*pathology MH - Myocardium/*pathology MH - Myositis/*complications/pathology MH - Pericarditis/complications/pathology MH - Prospective Studies MH - Support, U.S. Gov't, Non-P.H.S. MH - Weil's Disease/complications/*pathology RN - EC 2.7.3.- (Creatine Kinase Isoenzymes) RN - EC 2.7.3.2 (Creatine Kinase) RN - 60-27-5 (Creatinine) RN - 635-65-4 (Bilirubin) PT - JOURNAL ARTICLE DA - 900724 DP - 1990 Jul IS - 0022-1899 TA - J Infect Dis PG - 266-9 SB - A SB - M CY - UNITED STATES IP - 1 VI - 162 JC - IH3 AA - Author EM - 9009 AB - Information is lacking on the prevalence and severity of cardiac and striated muscle injury in late leptospirosis, and it is unclear whether patients with one type of myositis are at increased risk of developing another. Therefore, 38 patients with severe, late Weil's disease were evaluated for heart and skeletal muscle involvement: 37% had myositis and 39% had abnormal electrocardiograms (ECGs). First-degree atrioventricular heart block and changes suggestive of acute pericarditis were the most common ECG findings. Two patients had transient pericardial friction rubs, but neither pericardial effusion, shock, nor congestive heart failure occurred. Cardiac involvement was not associated with skeletal muscle injury (P = .35), although both manifestations were correlated with severity of disease. Thus, ECG changes and myositis were prominent features of late Weil's disease but cardiac morbidity was not. AD - Naval Medical Research Unit Number 2, Manila, Philippines. PMID- 2355200 SO - J Infect Dis 1990 Jul;162(1):266-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 91109610 AU - Bernasovskaia EP AU - Mel'nitskaia EV AU - Kondratenko VN TI - [The development of a complex Leptospira antigenic erythrocyte diagnostic agent] LA - Rus MH - Animal MH - Antibodies, Bacterial/blood MH - Antibody Specificity/immunology MH - Antigens, Bacterial/*diagnostic use/isolation & purification MH - Comparative Study MH - Cross Reactions/immunology MH - English Abstract MH - Erythrocytes/*immunology MH - Hemagglutination Tests MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 910225 DP - 1990 Jul-Aug IS - 0201-8462 TA - Mikrobiol Zh PG - 74-9 CY - USSR IP - 4 VI - 52 JC - MY8 AA - Author EM - 9105 AB - Blood-sensitive activity of antigenic extracts obtained from leptospiras using the supersound and sodium dodecyl sulphate has been studied. Erythrocytic diagnostica, obtained on the basis of the mentioned sensitines, possess the genus and serogroup specificity, which expands their diagnostic spectrum. New diagnostica are shown to possess higher sensitivity as compared with the previously developed leptospirosis genus-specific erythrocytic diagnostica. The data are presented confirming the prospects of development of erythrocytic diagnostica based on antigens of leptospiras obtained by means of a supersound and sodium dodecyl sulphate. These preparations may be used in the diagnosis of human and animal leptospirosis. PMID- 2273996 CU - 91 TT - Razrabotka leptospiroznogo kompleksnogo antigennogo eritrotsitarnogo diagnostikuma. EA - A SO - Mikrobiol Zh 1990 Jul-Aug;52(4):74-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 91075756 AU - Macura T AU - Jarczyk R TI - [Weil's disease complicated by subarachnoid hemorrhage and myocardial infarction] LA - Pol MH - Adult MH - Case Report MH - Cerebral Aneurysm/*complications MH - English Abstract MH - Human MH - Male MH - Myocardial Infarction/*etiology MH - Rupture, Spontaneous MH - Subarachnoid Hemorrhage/*etiology MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 910124 DP - 1990 Jul 1 IS - 0043-5147 TA - Wiad Lek PG - 685-7 CY - POLAND IP - 13 VI - 43 JC - XOA AA - Author EM - 9103 AB - A case of Weil' disease is described in a 32-year-old patient complicated by subarachnoid haemorrhage from ruptured cerebral aneurysm and anterolateral myocardial infarction. The differentiation of the complications in strict meaning of the word from inflammatory and toxic changes in the course of leptospirosis is often difficult. AD - Oddzialu Obserwacyjno-Zakaznego Wojewodzkiego Szpitala, Specjalistycznego w Tychach. PMID- 2256332 TT - Choroba Weila powiklana krowotokiem podpajeczynowkowym i zawalem serca. EA - A SO - Wiad Lek 1990 Jul 1;43(13):685-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 91049611 AU - Karabanov VR AU - Vinogradova GN AU - Galuzinskii VP TI - [The use of hemosorption in leptospirosis patients with pronounced thrombocytopenia] LA - Rus MH - Acute Disease MH - Adult MH - Case Report MH - Combined Modality Therapy/methods MH - English Abstract MH - *Hemoperfusion/contraindications/methods MH - Human MH - Male MH - Thrombocytopenia/blood/etiology/*therapy MH - Time Factors MH - Weil's Disease/blood/complications/*therapy PT - JOURNAL ARTICLE DA - 901204 DP - 1990 Jul IS - 0049-6804 TA - Vrach Delo PG - 114-6 CY - USSR IP - 7 JC - XLS AA - Author EM - 9102 AB - The authors describe a rare case from the clinical practice. Treatment including hemosorption was employed in a 38-year-old with a severe form of icterohemorrhagic leptospirosis accompanied by acute reno-hepatic failure and pronounced thrombocytopenia--15 x 10(9)l. The relative significance of thrombocytopenia as one of the main contraindication to hemosorption is suggested. PMID- 2238583 TT - Primenenie gemosorbtsii u bol'nykh leptospirozom s vyrazhennoi trombotsitopeniei. EA - A SO - Vrach Delo 1990 Jul;(7):114-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 91020889 AU - Yukawa M AU - Mochizuki K AU - Imamura S TI - Susceptibility of Mongolian gerbils (Meriones unguiculatus) to leptospires and the protective effect of vaccination. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Colony Count, Microbial MH - Comparative Study MH - Disease Susceptibility MH - *Gerbillinae MH - Guinea Pigs MH - Hamsters MH - Leptospira/growth & development/*immunology MH - Leptospirosis/immunology/prevention & control/*veterinary MH - Rodent Diseases/*immunology/prevention & control RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 901115 DP - 1990 Jul IS - 0378-1135 TA - Vet Microbiol PG - 63-71 SB - M CY - NETHERLANDS IP - 1 VI - 24 JC - XBW AA - Author EM - 9101 AB - Mongolian gerbils, Meriones unguiculatus, were shown to be highly susceptible to Leptospira interrogans serovars such as icterohaemorrhagiae, copenhageni, canicola, autumnalis, javanica, pyrogenes and hebdomadis as compared to guinea pigs and hamsters. Mortality with signs of haemorrhage and jaundice was recorded in all experimental rodents after intraperitoneal inoculation with all strains of the serovars indicated. However, Mongolian gerbils were comparatively susceptible to strains which were of low virulence to guinea pigs and hamsters. Use of leptospiral vaccination proved effective in protecting the animals against inoculum challenges. The Mongolian gerbil is a species that may be selectively and preferentially useful for assays on the protective effects of leptospiral vaccination. AD - Laboratory of Biomedical Science, College of Agriculture and Veterinary Medicine, Nihon University, Fujisawa, Japan. PMID- 2219666 CU - 91 SO - Vet Microbiol 1990 Jul;24(1):63-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [6 protein links] [202 medline neighbors] UI - 90307220 AU - Segers RP AU - van der Drift A AU - de Nijs A AU - Corcione P AU - van der Zeijst BA AU - Gaastra W TI - Molecular analysis of a sphingomyelinase C gene from Leptospira interrogans serovar hardjo. LA - Eng MH - Amino Acid Sequence MH - Base Sequence MH - Codon MH - Hemolysins/genetics MH - Leptospira interrogans/*enzymology MH - Molecular Sequence Data MH - Phosphoric Diester Hydrolases/*genetics MH - Sequence Homology, Nucleic Acid MH - Sphingomyelin Phosphodiesterase/*genetics/metabolism MH - Structure-Activity Relationship MH - Substrate Specificity MH - Support, Non-U.S. Gov't MH - Temperature RN - EC 3.1.4 (Phosphoric Diester Hydrolases) RN - EC 3.1.4.12 (Sphingomyelin Phosphodiesterase) RN - 0 (Codon) RN - 0 (Hemolysins) PT - JOURNAL ARTICLE DA - 900813 DP - 1990 Jul IS - 0019-9567 TA - Infect Immun PG - 2177-85 SB - M SB - X CY - UNITED STATES IP - 7 VI - 58 JC - GO7 AA - Author EM - 9010 AB - A thermolabile hemolysin from Leptospira interrogans serovar hardjo, strain Sponselee, was shown to specifically degrade sphingomyelin. Nucleotide sequence determination revealed that sphingomyelinase activity was encoded by an open reading frame of 1,668 nucleotides. Although a putative signal sequence could be identified, no evidence for protein export in either L. interrogans or Escherichia coli was obtained. The apparent molecular mass of the expression product in E. coli minicells was 41.2 kilodaltons, whereas open reading frame 1 encoded a protein of 63,268 daltons. The observed difference may be explained by processing at the carboxy-terminal part of the hemolysin in E. coli. A high degree of similarity on the DNA and protein levels with Staphylococcus aureus beta-hemolysin and sphingomyelinase C from three Bacillus cereus strains was observed. The presence of various sphingomyelinase genes within the L. interrogans species is demonstrated. AD - Department of Bacteriology, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands. PMID- 2163985 CU - 93 SI - GENBANK/X52176 SO - Infect Immun 1990 Jul;58(7):2177-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 92189431 AU - Andreescu N TI - A new prepatory method of thermically inactivated Leptospira Patoc antigen for rapid slide agglutination used as serosurvey test for human leptospiroses. LA - Eng MH - Agglutination Tests/methods MH - Antigens, Bacterial/*diagnostic use/isolation & purification MH - Comparative Study MH - Evaluation Studies MH - Heat MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Sensitivity and Specificity MH - Time Factors RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 920413 DP - 1990 Jul-Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 223-7 CY - ROMANIA IP - 3 VI - 49 JC - 8EM AA - Author EM - 9206 AB - 830 sera from leptospirosis-suspect patients and 133 sera from investigations were analysed by the new test--rapid slide agglutination with Patoc antigen, inactivated at 60 degrees C for 15 minutes, in parallel with two standard tests--CFT with merthiolated Patoc antigen and MAR with 17-23 live pathogenic antigens. The new serotest proved efficient for selecting the cases of disease or leptospira infection, acute or recent form, not older than 2 years, both by its sensitivity and specificity and also by its rapid and economical character. In the present paper, the technology of preparation and control of Patoc antigen, inactivated at 60 degrees C for 15 minutes, is described. AD - Cantacuzino Institute, Bucharest, Romania. PMID- 2134149 SO - Arch Roum Pathol Exp Microbiol 1990 Jul-Sep;49(3):223-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 91327109 AU - Nicodemo AC AU - Del Negro G AU - Amato Neto V TI - Thrombocytopenia and leptospirosis. LA - Eng MH - Antibodies/analysis MH - Blood Coagulation Tests MH - Blood Platelets/immunology MH - Disseminated Intravascular Coagulation/complications MH - Human MH - Leptospirosis/blood/*complications MH - Platelet Count MH - Prospective Studies MH - Thrombocytopenia/blood/*etiology MH - Urea/blood RN - 0 (Antibodies) RN - 57-13-6 (Urea) PT - JOURNAL ARTICLE DA - 910910 DP - 1990 Jul-Aug IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 252-9 CY - BRAZIL IP - 4 VI - 32 JC - S9D AA - Author EM - 9111 AB - The present study has intended to contribute to the elucidation of the pathogenic mechanisms, involved in the thrombocytopenia and in the bleeding diathesis seen in the course of Leptospirosis. The group of cases included in the present prospective study consisted of 30 patients with Leptospirosis, admitted to the Infectious and Parasitic Diseases Ward, Hospital das Clinicas, Faculty of Medicine, University of Sao Paulo. The following possible mechanisms of thrombocytopenia have been considered and therefore investigated: platelet consumption, due to disseminated intravascular coagulation; immune-mediated platelet destruction, due to platelet-associated antibodies and an inhibited platelet production in the bone marrow. Thrombocytopenia occurred in 86.6% of 30 patients and did not seem to be immune-mediated by platelet- associated antibodies. Furthermore it did not seem to be due to a disseminated intravascular coagulation consumption. Although there was a statistically-significant correlation between bone marrow platelet production and platelet counts we think that the static microscopic examination of a bone marrow aspirate cannot accurately depict the dynamic mechanisms of platelet production when these cells are being consumed in peripheral blood. Vasculitis should be considered as the most important factor for the pathogenesis of the bleeding disturbances in Leptospirosis. However, we believe that thrombocytopenia, uremia and coagulation disorders, individually or as a group, should be included among the contributing factors that lead to and worsen bleeding episodes, which represent the leading cause of death in this disease. AD - Department of Infectious Diseases, University of Sao Paulo Medical School, Brazil. PMID- 2101519 CU - 91 SO - Rev Inst Med Trop Sao Paulo 1990 Jul-Aug;32(4):252-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 91327106 AU - da Silva MV AU - Camargo ED AU - Vaz AJ AU - de Souza AM AU - Chieffi PP AU - Sakata EE TI - [Immunodiagnosis of human leptospirosis by ELISA-IgM, employing different antigenic preparations from prevalent serovars of Leptospira interrogans] LA - Por MH - Antigens, Bacterial/*analysis MH - Comparative Study MH - Cross Reactions MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - IgM/*analysis MH - Leptospira interrogans/classification/*immunology MH - Leptospirosis/*diagnosis MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 910910 DP - 1990 Jul-Aug IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 233-9 CY - BRAZIL IP - 4 VI - 32 JC - S9D AA - Author EM - 9111 AB - A comparative study among different serovars of Leptospira interrogans was performed in order to prepare antigens to detect IgM antibodies by ELISA in early and late phase of human leptospirosis. Ten serovars were chosen among the most prevalent detected by microscopic seroagglutination (SAM) in Sao Paulo city. Using ELISA-IgM five of them showed better results (canicola, hebdomadis, icterohaemorrhagiae, cynopteri and brasiliensis). These ones were also studied in a pool. The non-treated antigens showed higher reactivity than the Triton X-100 (4%/50 degrees C/4h). ELISA-IgM using individually or pool of non- treated antigens proved to be reliable with high sensitivity and should be used for an earlier diagnosis of leptospirosis, as a trial test. Faster diagnostic elucidation can be useful to detect epidemic situations, so, allowing epidemiological surveillance interventions. AD - Instituto Adolfo Lutz, Secao de Sorologia, Sao Paulo, Brasil. PMID- 2101517 CU - 91 TT - Imunodiagnostico da leptospirose humana atraves do teste ELISA-IgM, empregando-se diferentes preparacoes antigenicas a partir de sorotipos prevalentes de Leptospira interrogans. EA - A SO - Rev Inst Med Trop Sao Paulo 1990 Jul-Aug;32(4):233-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 91242744 AU - Miller DA AU - Wilson MA AU - Owen WJ AU - Beran GW TI - Porcine leptospirosis in Iowa. LA - Eng MH - Abortion, Veterinary/*epidemiology/microbiology MH - Animal MH - Antibodies, Bacterial/blood MH - Female MH - Fetal Death/epidemiology/microbiology/*veterinary MH - Iowa/epidemiology MH - Leptospira/classification/immunology/isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/epidemiology/microbiology/*veterinary MH - Support, U.S. Gov't, Non-P.H.S. MH - Swine MH - Swine Diseases/*epidemiology/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910702 DP - 1990 Jul IS - 1040-6387 TA - J Vet Diagn Invest PG - 171-5 SB - M CY - UNITED STATES IP - 3 VI - 2 JC - A2D AA - Author EM - 9109 AB - The epidemiology of leptospirosis in Iowa swine was examined on the basis of serologic results and herd data from 55 herds in the National Animal Health Monitoring System (NAHMS) program and culture results and histories from 578 cases of reproductive failure submitted to the Iowa Veterinary Diagnostic Laboratory during a 3-year period. Thirty-eight percent of sera from NAHMS herds contained antibodies against 1 or more of 12 leptospira antigens. Leptospires were isolated from 9 (1.6%) of 578 cases of reproductive failure. Seven (78%) of the isolates were identified as Leptospira interrogans serovar kennewicki and 2 (22%) as serovar grippotyphosa. In 7 herds from which leptospires were isolated, attack rates ranged from 1% to 84%. Clinical leptospirosis, characterized by reproductive failure and confirmed by isolation of leptospires, was sporadic. No significant differences in farrowing averages and reproductive problems were observed between vaccinated and nonvaccinated NAHMS herds or between herds with higher (43-63%) or lower (14-40%) percentages of animals that were serologically positive against serovar bratislava. AD - National Veterinary Services Laboratories, US Department of Agriculture, Ames, IA 50010. PMID- 2094443 CU - 91 SO - J Vet Diagn Invest 1990 Jul;2(3):171-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 90342200 AU - Rocha T TI - Isolation of Leptospira interrogans serovar mozdok from aborted swine fetuses in Portugal. LA - Eng MH - Abortion, Veterinary/*etiology/microbiology MH - Animal MH - Female MH - Fetus/*microbiology MH - Leptospira interrogans/*isolation & purification MH - Portugal MH - Pregnancy MH - Swine MH - Swine Diseases/*etiology/microbiology MH - Weil's Disease/complications/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 900910 DP - 1990 Jun 16 IS - 0042-4900 TA - Vet Rec PG - 602 SB - M CY - ENGLAND IP - 24 VI - 126 JC - XBS EM - 9011 AD - Bacteriology Department, Laboratorio Nacional de Investigacao Veterinaria, Lisboa, Portugal. PMID- 2382358 SO - Vet Rec 1990 Jun 16;126(24):602 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 90352114 TI - Leptospirosis. LA - Eng LA - Fre MH - Agriculture MH - Environmental Exposure MH - France MH - Human MH - Incidence MH - Leptospira interrogans/classification MH - Leptospirosis/*epidemiology/etiology/immunology MH - Refuse Disposal MH - Seasons MH - Serotyping MH - Urban Population PT - JOURNAL ARTICLE DA - 900924 DP - 1990 Jun 8 IS - 0049-8114 TA - Wkly Epidemiol Rec PG - 175-6 CY - SWITZERLAND IP - 23 VI - 65 JC - AVX EM - 9011 PMID- 2386699 NI - A SO - Wkly Epidemiol Rec 1990 Jun 8;65(23):175-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 90361271 AU - Yan R AU - Zhao H AU - Li S AU - Dai B TI - [Study on the characteristics of agglutination reaction of McAb with Leptospira interrogans outer envelope] LA - Chi MH - Agglutination Tests/methods MH - Animal MH - Antibodies, Monoclonal/*biosynthesis MH - Bacterial Outer Membrane Proteins/*immunology MH - Cell Fusion MH - English Abstract MH - Leptospira interrogans/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Bacterial Outer Membrane Proteins) PT - JOURNAL ARTICLE DA - 901004 DP - 1990 Jun IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 137-40 CY - CHINA IP - 2 VI - 21 JC - GEB AA - Author EM - 9012 AB - Three McAb were produced against an outer envelope preparation from Leptospira, interrogans, serovar Lai by fusion of SP2/0 myeloma cells with immune BALB/c mice spleen cells. The fusion rate was 96% and the antibody positive rate was 50%. One of the hybridomas, E4B11C9, reacted with 13 of the 13 serovars of the Icterohaemorrhagiae serogroup in microscopic agglutination test (MAT) but did not react with the 18 representative serovars of L. interrogans and L. biflexa serovar patoc and Leptonema illini. For all non-reactive serovars the MAT titres were greater than 1:25. The McAb, E4B7G5, reacted similarly with all serovars except smithi and tonkini. E4B7D4 reacted also similarly with all serovars except serovars birkini, ndambari, bogvere, smithi and tonkini. Therefore, 3 McAb showed serogroup specificity and partial serogroup specificity by agglutination. The agglutination titres were high and hybridomas were stable, so it might be useful in providing a simple, rapid method for the classification and identification of clinical isolates such as pathogenic L. interrogans in place of the complicated and time-consuming conventional methods. PMID- 2391093 CU - 91 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1990 Jun;21(2):137-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 90266809 AU - Barton LL AU - Friedman AD TI - The platelet count in Kawasaki syndrome [letter; comment] LA - Eng MH - Blood Platelets/*analysis MH - Case Report MH - Child MH - Diagnosis, Differential MH - Human MH - Leptospirosis/*blood MH - Mucocutaneous Lymph Node Syndrome/*blood PT - COMMENT PT - LETTER DA - 900702 DP - 1990 Jun IS - 0002-922X TA - Am J Dis Child PG - 617-8 SB - A SB - M SB - X CY - UNITED STATES IP - 6 VI - 144 JC - 3GS EM - 9009 CM - Comment on: Am J Dis Child 1990 Jan;144(1):19-20 RO - M:LC2 PMID- 2386591 LR - 900918 CU - 91 SO - Am J Dis Child 1990 Jun;144(6):617-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 90327333 AU - Golterman LK AU - de Jong GM TI - [A patient with fever and pain in the extremities] LA - Dut MH - Antibodies, Bacterial/isolation & purification MH - Case Report MH - Child MH - Diagnosis, Differential MH - English Abstract MH - Enteritis/diagnosis MH - Enzyme-Linked Immunosorbent Assay MH - Fever/*etiology MH - Human MH - Male MH - Pain/*etiology MH - Rheumatic Diseases/diagnosis MH - Weil's Disease/complications/*diagnosis/immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900830 DP - 1990 Jun IS - 0376-7442 TA - Tijdschr Kindergeneeskd PG - 92-4 SB - M CY - NETHERLANDS IP - 3 VI - 58 JC - VST AA - Author EM - 9011 AB - During holidays in Suriname a six year old boy fell ill with high fever, general malaise, pain in the extremities and abdomen and vomiting. Because of a tentative diagnosis of acute rheumatism or bacterial enteritis amoxicillin and salicylates were started. After his return to the Netherlands an increased ESR and impaired renal and hepatic functions were found. The history revealed contact with sewage water. Further analysis established the diagnosis of Leptospirosis. This comparatively rare clinical entity, seldom mentioned in paediatric literature, is discussed. AD - Afd. Kindergeneeskunde, Westeinde Ziekenhuis, Den Haag. PMID- 2375042 CU - 91 TT - Een patient met koorts en pijn in de extremiteiten. EA - A SO - Tijdschr Kindergeneeskd 1990 Jun;58(3):92-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 90299016 AU - Gale DA AU - Everard CO AU - Carrington DG AU - Everard JD TI - Leptospiral antibodies in patients from a Barbadian general practice. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Barbados/epidemiology MH - Female MH - Human MH - Leptospira/classification/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/*epidemiology MH - Male MH - Occupations MH - Support, Non-U.S. Gov't MH - Weil's Disease/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900806 DP - 1990 Jun IS - 0392-2990 TA - Eur J Epidemiol PG - 150-5 SB - M CY - ITALY IP - 2 VI - 6 JC - ERE AA - Author EM - 9010 AB - Sera from 1,419 patients who attended a Barbadian general practice for a variety of complaints between 1 April 1984 and 30 April 1988 were examined for leptospiral agglutinins by the microscopic agglutination test (MAT). Sera from the 42 patients with pyrexia of unknown origin, jaundice or kidney involvement, and the 26 patients with titres greater than or equal to 1:400 in the MAT, were also examined by the ELISA for IgM and IgG antibodies. Current or recent mild leptospiral infection was diagnosed in four of the patients, but some mild cases may have been missed. Two further cases of leptospirosis were recorded after the study period ended; both were very ill but responded well to doxycycline therapy. Altogether 177 of the 1,419 patients (12.5%) had agglutination titres greater than or equal to 1:50. These were 104/739 males (14%) and 73/680 females (11%). Seropositivity tended to increase with age (p less than 0.01), and the highest rates were in agricultural workers (35%), labourers (24%) and non-manual outdoor workers (19%). The difference in seropositivity between the main occupational groups was highly significant (p less than 0.001). The serogroups most commonly recorded among the seropositive patients were Autumnalis (31%), Panama (26%), Australis (24%) and Pyrogenes (20%). Autumnalis predominated in each of the main occupational groups except indoor non- manual workers where Panama, Pyrogenes and Australis occurred more frequently. 95% of the positive titres ranged between 1:50 and 1:400. Titres tended to increase with age, but there was no obvious association between higher titres and particular occupations.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Westgate Clinic, Barbarees Hill, Bridgetown, Barbados. PMID- 2361539 CU - 91 SO - Eur J Epidemiol 1990 Jun;6(2):150-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 90295046 AU - Foti G AU - Masseo A AU - Raimo C AU - Mangano C AU - Foti N TI - [On the subject of leptospirosis. Description of a case] LA - Ita MH - Adult MH - Case Report MH - English Abstract MH - Human MH - Italy/epidemiology MH - Leptospirosis/*diagnosis/epidemiology MH - Male PT - JOURNAL ARTICLE DA - 900802 DP - 1990 Jun IS - 0026-4806 TA - Minerva Med PG - 495-7 SB - M SB - X CY - ITALY IP - 6 VI - 81 JC - N6M AA - Author EM - 9010 AB - The Authors report a case of leptospirosis. Stress is laid on the sporadicity of this infection in their region; attention is also drawn to the variety of the clinical expression of this disease. AD - Divisione Malattie Infettive, U.S.L. n. 31, Presidio Ospedali Riuniti, Reggio Calabria. PMID- 2359505 TT - In tema di leptospirosi. Segnalazione di un caso. EA - A SO - Minerva Med 1990 Jun;81(6):495-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 90264349 AU - Hsu D AU - Pan MJ AU - Zee YC AU - LeFebvre RB TI - Unique ribosome structure of Leptospira interrogans is composed of four rRNA components. LA - Eng MH - Leptospira interrogans/*genetics MH - Ribosomes/*analysis MH - RNA, Ribosomal/*analysis MH - RNA, Ribosomal, 23S/*analysis RN - 0 (RNA, Ribosomal) RN - 0 (RNA, Ribosomal, 23S) PT - JOURNAL ARTICLE DA - 900703 DP - 1990 Jun IS - 0021-9193 TA - J Bacteriol PG - 3478-80 SB - M CY - UNITED STATES IP - 6 VI - 172 JC - HH3 AA - Author EM - 9009 AB - All known ribosomes of procaryotic organisms are made up of three rRNA components that are 23, 16, and 5S in size. We now report that in some Leptospira interrogans strains, the classical 23S rRNA is further processed to generate 14 and 17S rRNAs. This processing step was previously known to occur only in some eucaryotes and in a small group of procaryotes. The implications of this finding are discussed. AD - Department of Veterinary Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis 95616. PMID- 2345155 CU - 92 SO - J Bacteriol 1990 Jun;172(6):3478-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [218 medline neighbors] UI - 90264322 AU - Fukunaga M AU - Horie I AU - Mifuchi I TI - Isolation and characterization of the 5S rRNA gene of Leptospira interrogans. LA - Eng MH - Base Sequence MH - DNA, Bacterial/analysis MH - *Genes, Bacterial MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - RNA, Ribosomal/*genetics MH - RNA, Ribosomal, 5S/*genetics RN - 0 (DNA, Bacterial) RN - 0 (RNA, Ribosomal) RN - 0 (RNA, Ribosomal, 5S) PT - JOURNAL ARTICLE DA - 900703 DP - 1990 Jun IS - 0021-9193 TA - J Bacteriol PG - 3264-8 SB - M CY - UNITED STATES IP - 6 VI - 172 JC - HH3 AA - Author EM - 9009 AB - The gene encoding the 5S rRNA for Leptospira interrogans serovar canicola strain Moulton was isolated and sequenced. The 5S rRNA gene occurs as a single copy within the genome and encodes a 117-nucleotide- long RNA molecule. The 5S rRNA gene is flanked at both the 5' and 3' ends by regions of A + T-rich sequences, and the 5'-flanking region contains a promoter sequence. L. interrogans has a unique and remarkable organization of the 5S rRNA gene. The 5S rRNA molecule exhibits a strong similarity to typical eubacterial 5S rRNA in terms of overall secondary structure, while the primary sequence is conserved to a lesser degree. Restriction analysis of the 5S rRNA gene indicated that the DNA sequence including the 5S rRNA gene is highly conserved in the genomes of parasitic leptospires. AD - Faculty of Pharmacy and Pharmaceutical Science, University of Fukuyama, Hiroshima, Japan. PMID- 2345145 CU - 93 SI - GENBANK/D90074 SO - J Bacteriol 1990 Jun;172(6):3264-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 91024854 AU - Rothwell JT TI - Serum agglutinating antibodies to Leptospira interrogans serovar canicola presumed due to serovar robinsoni infection in an Australian dog. LA - Eng MH - Animal MH - Antibodies, Bacterial/*blood MH - Case Report MH - Cross Reactions MH - Dog Diseases/*immunology/microbiology MH - Dogs MH - Leptospira canicola/*immunology MH - Leptospirosis/immunology/microbiology/*veterinary MH - Male RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 901109 DP - 1990 Jun IS - 0005-0423 TA - Aust Vet J PG - 232 SB - M CY - AUSTRALIA IP - 6 VI - 67 JC - 9IE EM - 9101 AD - New South Wales Agriculture and Fisheries, Regional Veterinary Laboratory, Camden. PMID- 2222370 CU - 91 SO - Aust Vet J 1990 Jun;67(6):232 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 91024355 AU - Everard CO AU - Maude GH AU - Hayes RJ TI - Leptospiral infection: a household serosurvey in urban and rural communities in Barbados and Trinidad. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Antibodies, Bacterial/analysis MH - Barbados MH - Child MH - Child, Preschool MH - Cluster Analysis MH - Female MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*epidemiology/immunology MH - Longitudinal Studies MH - Male MH - Middle Age MH - Risk Factors MH - Rural Health MH - Support, Non-U.S. Gov't MH - Trinidad and Tobago MH - Urban Health RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 901109 DP - 1990 Jun IS - 0003-4983 TA - Ann Trop Med Parasitol PG - 255-66 SB - M CY - ENGLAND IP - 3 VI - 84 JC - 68E AA - Author EM - 9101 AB - A longitudinal study of leptospiral agglutinins in subjects five years of age and over was undertaken in Trinidad and Barbados between 1980 and 1982. Households were sampled randomly from one urban and two rural communities on each island, giving a total of 576 eligible individuals in Barbados and 524 in Trinidad. Participants were examined three times at approximately annual intervals. The prevalence of seropositivity at a titre of 1:50 using the microscopic agglutination test was 18.5% in Barbados and 21.9% in Trinidad. Prevalence increased steeply with age in both sexes and was higher in males than females on both islands. There was a marked difference in predominating serogroups on the two islands--Autumnalis (42% of positive cases) predominated in Barbados while Bataviae (29% of positive cases) predominated in Trinidad. Estimates of incidence rates for seroconversion were 2.9% per annum for Barbados and 3.5% per annum for Trinidad. Occupational risk varied between the islands, but in both cases highest seropositivity rates (greater than 50%) were found in outdoor labourers and lowest were found in indoor non-manual workers and urban homeworkers. In Barbados seroprevalence was higher among persons who cleared drains or who had contact with livestock. Lack of an inside toilet was associated with an increase in seropositivity on both islands. There was little evidence of household clustering of seropositive cases. AD - Leptospira Laboratory, St. Michael, Barbados, W.I. PMID- 2222028 CU - 91 SO - Ann Trop Med Parasitol 1990 Jun;84(3):255-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 90338387 AU - Kurashige S AU - Bissett M AU - Oshiro L TI - Characterization of a tick isolate of Borrelia burgdorferi that possesses a major low-molecular-weight surface protein. LA - Eng MH - Animal MH - Antibodies, Monoclonal/immunology MH - Bacterial Outer Membrane Proteins/*analysis MH - Borrelia burgdorferi/*ultrastructure MH - In Vitro MH - Leptospira/ultrastructure MH - Mice MH - Mice, Inbred BALB C MH - Molecular Weight MH - Ticks/*microbiology MH - Treponema pallidum/ultrastructure RN - 0 (Antibodies, Monoclonal) RN - 0 (Bacterial Outer Membrane Proteins) PT - JOURNAL ARTICLE DA - 900912 DP - 1990 Jun IS - 0095-1137 TA - J Clin Microbiol PG - 1362-6 SB - M CY - UNITED STATES IP - 6 VI - 28 JC - HSH AA - Author EM - 9011 AB - An unusual strain of Borrelia burgdorferi (DN 127 cl 9-2) that was isolated from an Ixodes pacificus tick did not react with monoclonal antibodies (MAbs) to OspA and OspB surface proteins, which are found in most U.S. strains. The strain exhibited an abundant protein with an apparent molecular weight of 25,000 (25K protein). A MAb, 86 DN-1, that was prepared to the 25K protein was used in studies on the effect of proteases on the intact spirochetes, immune electron microscopy, and Western blot (immunoblot) analyses; the results indicated that the low- molecular-weight protein was an apparent surface protein that was loosely attached to the spirochete. Five tick isolates from California possessed low-molecular-weight proteins in the 20,000- to 25,000- molecular-weight range that reacted with the 86 DN-1 MAb. The 25K protein of DN 127 cl 9-2 was unaffected by prolonged in vitro passage of cultures in BSK II medium, while the low-molecular-weight proteins of the other strains of B. burgdorferi from California either decreased in quantity or became undetectable on long-term in vitro passage. AD - Microbial Diseases Laboratory, California Department of Health Services, Berkeley 94704. PMID- 2199499 CU - 91 SO - J Clin Microbiol 1990 Jun;28(6):1362-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 91024850 AU - Ellis TM AU - Masters HG AU - Hustas L AU - Sutherland SS AU - Evans R TI - The effect of selenium supplementation on antibody response to bacterial antigens in merino sheep with a low selenium status. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Antigens, Bacterial/*immunology MH - Bacterial Vaccines/immunology MH - Brucella abortus/immunology MH - Complement Fixation Tests MH - Corynebacterium/immunology MH - Enzyme-Linked Immunosorbent Assay MH - Leptospira interrogans/immunology MH - Male MH - Random Allocation MH - Selenium/analysis/*pharmacology MH - Sheep/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Vaccines) RN - 7782-49-2 (Selenium) PT - JOURNAL ARTICLE DA - 901109 DP - 1990 Jun IS - 0005-0423 TA - Aust Vet J PG - 226-8 SB - M CY - AUSTRALIA IP - 6 VI - 67 JC - 9IE EM - 9101 AD - Animal Health Laboratories, Department of Agriculture, Baron-Hay Court, South Perth, Western Australia. PMID- 2121126 CU - 91 SO - Aust Vet J 1990 Jun;67(6):226-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 90380205 AU - Isogai E AU - Isogai H AU - Fujii N AU - Oguma K TI - Macrophage activation by leptospiral lipopolysaccharide. LA - Eng MH - Animal MH - Dose-Response Relationship, Drug MH - Interferons/biosynthesis MH - Interleukin-2/biosynthesis MH - Leptospira interrogans/*immunology MH - Lipopolysaccharides/analysis/*immunology MH - Liver/analysis MH - Lymph Nodes/metabolism MH - *Macrophage Activation MH - Macrophages/immunology/metabolism MH - Male MH - Mice MH - Spleen/analysis RN - 0 (Lipopolysaccharides) RN - 9008-11-1 (Interferons) PT - JOURNAL ARTICLE DA - 901026 DP - 1990 Jun IS - 0934-8840 TA - Int J Med Microbiol PG - 200-8 SB - M CY - GERMANY, WEST IP - 2 VI - 273 JC - AC2 AA - Author EM - 9012 AB - Leptospiral lipopolysaccharides (LPSs) extracted from Leptospira interrogans serovars copenhageni and hebdomadis were tested for the ability to induce macrophage activation. In-vitro analysis showed that each leptospiral LPS was a potent activator to macrophages. After stimulation with the LPSs, interleukin-1 (IL-1) secretion, interferon (IFN) production and chemiluminescence (CL) response were induced. Intravenous high-dose injection of the leptospiral LPSs induced various lesions such as necrosis of the liver, and the LPSs were detected in macrophages in the liver, spleen and lymphnodes by immunohistochemical examination. Enhancement of macrophage activity in mice inoculated with low doses of leptospiral LPS was recognized. The macrophages of the LPS- treated mice showed a significantly higher bactericidal action than those of control mice. The beta-galactosidase and nitroblue tetrazolium (NBT) positive cells in macrophages of the LPS-treated mice increased significantly. In the NBT reduction test after phagocytosis of latex beads or Salmonella typhimurium, the macrophages of the LPS-treated mice showed a significantly higher activity than those of control mice. AD - Department of Preventive Dentistry, School of Dentistry, Higashi Nippon Gakuen University, Hokkaido, Japan. PMID- 1698063 CU - 95 SO - Int J Med Microbiol 1990 Jun;273(2):200-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 90307053 AU - Segers RP AU - De Nijs A AU - van Kooten PJ AU - Gaastra W AU - van der Zeijst BA TI - The use of immunodeficient male (CBA/N x BALB/c) F1 mice to produce monoclonal antibodies directed to proteins of Leptospira interrogans rather than to immunodominant lipopolysaccharides. LA - Eng MH - Animal MH - Antibodies, Bacterial/immunology MH - Antibodies, Monoclonal/*biosynthesis/immunology MH - Antigens, Bacterial/immunology MH - Bacterial Proteins/*immunology MH - Blotting, Western MH - Cell Line MH - Enzyme-Linked Immunosorbent Assay MH - Epitopes/immunology MH - Hybridomas MH - Leptospira interrogans/*immunology MH - Lipopolysaccharides/immunology MH - Male MH - Mice MH - Spleen/immunology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) RN - 0 (Epitopes) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 900813 DP - 1990 Jun IS - 0272-457X TA - Hybridoma PG - 275-83 SB - M CY - UNITED STATES IP - 3 VI - 9 JC - GFS AA - Author EM - 9010 AB - A method, using an immunodeficient mouse strain, for the production of monoclonal antibodies directed exclusively against the proteins in an antigen mixture also containing immunodominant LPS, is described. Male (CBA/N x BALB/c) F1 mice were immunized with an outer envelope antigen mixture from Leptospira interrogans strain Wijnberg containing both lipopolysaccharides and proteins. The immune response in these mice was shown to be predominantly directed against protein antigens. Hybridoma cell lines were generated by fusing spleen cells from a (CBA/N x BALB/c) F1 mouse with BALB/c Sp2/0 plasmacytoma cells. Hybridoma cell lines producing monoclonal antibodies reacting with the outer envelope preparation were identified by ELISA. All epitopes recognized by the monoclonal antibodies are sensitive to proteinase K degradation and resistant to oxidation by periodate indicating that they are located on proteins. All epitopes are located on a 35 kDa protein and specific for the pathogenic L. interrogans species. AD - Department of Bacteriology, State University of Utrecht, The Netherlands. PMID- 1694817 CU - 95 SO - Hybridoma 1990 Jun;9(3):275-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 90270076 AU - Bolin CA AU - Cassells JA TI - Isolation of Leptospira interrogans serovar bratislava from stillborn and weak pigs in Iowa. LA - Eng MH - Animal MH - Animals, Newborn/microbiology MH - Antibodies, Bacterial/analysis MH - Culture Media MH - Female MH - Fetal Death/microbiology/*veterinary MH - Fluorescent Antibody Technique MH - Kidney/microbiology MH - Leptospira interrogans/immunology/*isolation & purification MH - Lung/microbiology MH - Placenta/microbiology MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/veterinary MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*microbiology MH - Weil's Disease/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 900709 DP - 1990 May 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1601-4 SB - M CY - UNITED STATES IP - 10 VI - 196 JC - HAV AA - Author EM - 9009 AB - Leptospira interrogans serovar bratislava was isolated from a herd of swine in Iowa with a history of stillborn and weak neonatal pigs. Placentas, kidneys, and lungs of stillborn and weak pigs from 3 litters were processed to detect leptospires by use of bacteriologic culture and fluorescent antibody testing. Sera from stillborn and weak pigs were tested to detect agglutinating antibody against leptospires. A low antibody titer against L interrogans serovar bratislava was detected in the sera of stillborn and weak pigs. Small numbers of leptospires were sometimes detected in tissues by use of the fluorescent antibody test. Serovar bratislava was isolated from placentas, stillborn pigs or weak pigs from each of the 3 litters. AD - Leptospirosis and Mycobacteriosis Research Unit, USDA, National Animal Disease Center, Ames, IA 50010. PMID- 2189848 CU - 91 SO - J Am Vet Med Assoc 1990 May 15;196(10):1601-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 90350361 AU - Durchfeld B AU - Baumgartner W AU - Herbst W AU - Brahm R TI - Vaccine-associated canine distemper infection in a litter of African hunting dogs (Lycaon pictus). LA - Eng MH - Animal MH - *Carnivora MH - Distemper/*etiology MH - Distemper Virus, Canine/*immunology MH - Female MH - Male MH - Support, Non-U.S. Gov't MH - Vaccination/adverse effects/*veterinary MH - Viral Vaccines/*adverse effects RN - 0 (Viral Vaccines) PT - JOURNAL ARTICLE DA - 900920 DP - 1990 May IS - 0931-1793 TA - Zentralbl Veterinarmed [B] PG - 203-12 CY - GERMANY, WEST IP - 3 VI - 37 JC - Y72 AA - Author EM - 9011 AB - Four, 57 days old, African hunting dog puppies (Lycaon pictus) from one litter died within three weeks following vaccination with modified-live canine distemper virus (CDV) and killed canine adenovirus type 1, canine parvovirus and Leptospira icterohemorrhagiae and canicola. 18 days post vaccination, the animals developed neurologic disease characterized by episodes of grand mal seizures and circling. Macroscopic, histological and immunohistochemical studies revealed acute systemic CDV infection with acute encephalopathy. Virus isolation attempts using primary dog kidney cells, lung macrophages and Vero cells were negative. Therefore, the question whether the infection was the result of vaccination or natural infection remains open. The benefits and risks regarding the use of modified-live CDV vaccines and killed canine distemper vaccines in exotic carnivores are briefly discussed. AD - Institut fur Veterinar-Pathologie, Justus-Liebig-Universitat Giessen. PMID- 2385981 CU - 92 SO - Zentralbl Veterinarmed [B] 1990 May;37(3):203-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 90337748 AU - Gollop JH AU - Pang L AU - Sasaki DM TI - Leptospirosis: a possible cause of "aseptic meningitis". LA - Eng MH - Diagnosis, Differential MH - Human MH - Incidence MH - Leptospirosis/complications/*diagnosis/epidemiology MH - Medical Records MH - Meningitis/*diagnosis MH - Meningitis, Aseptic/*diagnosis/etiology PT - JOURNAL ARTICLE DA - 900907 DP - 1990 May IS - 0017-8594 TA - Hawaii Med J PG - 162, 165 CY - UNITED STATES IP - 5 VI - 49 JC - G1D EM - 9011 AD - Epidemiology Branch, Hawaii State Department of Health. PMID- 2380062 CU - 90 SO - Hawaii Med J 1990 May;49(5):162, 165 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 90277834 AU - Magnarelli LA AU - Anderson JF AU - McAninch JB TI - Serologic analyses of cottontail rabbits for antibodies to Borrelia burgdorferi. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial MH - Borrelia burgdorferi/*immunology MH - Cross Reactions MH - Disease Vectors MH - Enzyme-Linked Immunosorbent Assay MH - Lyme Disease/transmission MH - Rabbits/*immunology/microbiology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 900717 DP - 1990 May IS - 0095-1137 TA - J Clin Microbiol PG - 890-3 SB - M CY - UNITED STATES IP - 5 VI - 28 JC - HSH AA - Author EM - 9009 AB - An enzyme-linked immunosorbent assay was developed to detect antibodies to Borrelia burgdorferi in cottontail rabbits captured in Millbrook, N.Y., and New York, N.Y. Five antigenically variable strains of B. burgdorferi were analyzed to determine the variability of serologic test results. In analyses of 79 serum samples, seropositivity ranged from 56% for a strain cultured from kidney tissues of a cottontail rabbit to 68% for a strain isolated from a larva of Ixodes dentatus, a tick that parasitized a cottontail rabbit. There were false-positive results when reference rabbit antisera to B. hermsii and Treponema pallidum were screened against B. burgdorferi. Cross-reactivity with antisera to Leptospira interrogans serovars was less pronounced. Western blot (immunoblot) analyses revealed reactivities of test sera to two or more surface or subsurface proteins of B. burgdorferi with approximate molecular masses of 18, 25 to 27, 34, 36, 41, and 59 kilodaltons. Cottontail rabbits respond immunologically to B. burgdorferi, but the observed variations in serologic test results should not be a limitation in field and laboratory investigations of Lyme borreliosis. AD - Department of Entomology, Connecticut Agricultural Experiment Station, New Haven 06504. PMID- 2351732 CU - 91 SO - J Clin Microbiol 1990 May;28(5):890-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 90259443 AU - Nield H TI - Leptospirosis. Weil's disease. LA - Eng MH - Agricultural Workers' Diseases/epidemiology/*prevention & control MH - Animal MH - Animals, Domestic MH - Disease Reservoirs MH - Great Britain/epidemiology MH - Human MH - Risk Factors MH - Weil's Disease/epidemiology/*prevention & control/transmission PT - JOURNAL ARTICLE DA - 900628 DP - 1990 May IS - 0029-7917 TA - Occup Health (Lond) PG - 140-2 SB - N CY - ENGLAND IP - 5 VI - 42 JC - ODB EM - 9008 PMID- 2342748 LI - N SO - Occup Health (Lond) 1990 May;42(5):140-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 90233885 AU - Watt G TI - Leptospirosis as a cause of uveitis [letter; comment] LA - Eng MH - *Eye Infections, Bacterial/diagnosis MH - Human MH - Leptospirosis/*complications/diagnosis/transmission MH - Travel MH - Uveitis/*etiology PT - COMMENT PT - LETTER DA - 900531 DP - 1990 May IS - 0003-9926 TA - Arch Intern Med PG - 1130, 1132 SB - A SB - M SB - X CY - UNITED STATES IP - 5 VI - 150 JC - 7FS EM - 9008 CM - Comment on: Arch Intern Med 1989 May;149(5):1173-6 RO - M:LC1 PMID- 2331195 LR - 900814 CU - 91 SO - Arch Intern Med 1990 May;150(5):1130, 1132 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 91215092 AU - Sauca G AU - Cabre M AU - Valls F AU - Diestre G TI - [Visualization of spirochetes in conventional blood cultures from a patient with Weil's disease (letter)] LA - Spa MH - Aged MH - Blood/microbiology MH - Case Report MH - Human MH - Leptospira interrogans/*isolation & purification MH - Male MH - Microscopy/methods MH - Weil's Disease/blood/*microbiology PT - LETTER DA - 910606 DP - 1990 May IS - 0213-005X TA - Enferm Infecc Microbiol Clin PG - 326-7 CY - SPAIN IP - 5 VI - 8 JC - A10 EM - 9108 PMID- 2090244 TT - Visualizacion de espiroquetas en hemocultivos convencionales en un paciente con enfermedad de Weil. SO - Enferm Infecc Microbiol Clin 1990 May;8(5):326-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 91212702 AU - Regalado Segui JD AU - Lopez Acosta C AU - Pedroso Pena P AU - Ramos Perez LR TI - [Serologic study of patients with leptospirosis using TR antigen] LA - Spa MH - Antigens, Bacterial/*immunology MH - Comparative Study MH - English Abstract MH - Epitopes/*immunology MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Sensitivity and Specificity RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 910528 DP - 1990 May-Aug IS - 0375-0760 TA - Rev Cubana Med Trop PG - 208-18 CY - CUBA IP - 2 VI - 42 JC - RPX AA - Author EM - 9108 AB - This paper deals with 254 monosera of patients with leptospirosis verified by macroagglutination test with thermoresistant antigen (TR antigen) and passive hemaglutination (HA), as reference technique. The TR antigen was elaborated according to the method described by Mailloux and coworkers, 1974, with modifications, and it showed a wide generic reactivity. It was specific when serologic test were performed with hyperimmune sera obtained from febrile disease producing bacteria and the causal agent of syphilis. The results obtained by both serologic tests were compared and it was observed that 106 sera (41.73%) were reactive to HA, which showed a highly significant statistical difference between the two techniques; so a lower sensibility of TR macroagglutination test was determined. AD - Instituto de Medicina Tropical Pedro Kouri, Laboratorio Nacional de Referencia de Leptospiras. PMID- 1708510 CU - 95 TT - Estudio serologico de pacientes con leptospirosis mediante el antigeno TR. EA - A SO - Rev Cubana Med Trop 1990 May-Aug;42(2):208-18 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 91082168 AU - Kuriakose M AU - Eapen CK AU - Punnoose E AU - Koshi G TI - Leptospirosis--clinical spectrum and correlation with seven simple laboratory tests for early diagnosis in the Third World [see comments] LA - Eng MH - Adult MH - Aged MH - Amylases/blood MH - Enzyme Tests MH - Female MH - Human MH - Leptospirosis/*diagnosis/drug therapy MH - Male MH - Middle Age MH - Penicillins/therapeutic use MH - Serodiagnosis RN - EC 3.2.1.- (Amylases) RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 910125 DP - 1990 May-Jun IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 419-21 SB - M CY - ENGLAND IP - 3 VI - 84 JC - WBU AA - Author EM - 9104 AB - Twenty-four patients who were clinically suspected of having leptospirosis were subjected to 7 simple commonly available laboratory tests. The 21 patients who had 3 or more positive tests were confirmed serologically to have leptospirosis. The high frequency of acute abdominal pain (71.4%) as a major presenting symptom and the laboratory findings of raised serum amylase levels in a high percentage of patients (84.2%) were especially noteworthy. AD - Department of Medicine, M.O.S.C. Medical Mission Hospital, Kerala, India. CM - Comment in: Trans R Soc Trop Med Hyg 1991 Sep-Oct;85(5):698-9 RO - M:LC1 PMID- 1701935 LR - 920625 CU - 95 SO - Trans R Soc Trop Med Hyg 1990 May-Jun;84(3):419-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 90237134 AU - Masuzawa T AU - Nakamura R AU - Shimizu T AU - Yanagihara Y TI - Heat stability of protective antigen of Leptospira interrogans serovar lai. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial/analysis/*immunology MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Heat MH - Immunization MH - Immunoblotting MH - Leptospira interrogans/*immunology MH - Mice MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 900604 DP - 1990 Apr IS - 0095-1137 TA - J Clin Microbiol PG - 660-3 SB - M CY - UNITED STATES IP - 4 VI - 28 JC - HSH AA - Author EM - 9008 AB - Protective antigen (PAg; glycolipid antigen; molecular size, 23 to 30 kilodaltons), the serogroup-specific antigen partially purified from leptospiral cells, is one of the most important protective antigens. The heat stability of PAg was compared with that of whole-cell (WC) antigen by using sodium dodecyl sulfate-polyacrylamide gel electrophoresis, immunoblotting, protective activity, opsonin-inducing activity, agglutinating antibody-inducing activity, and an inhibition test in an enzyme-linked immunosorbent assay. A band of 23 to 30 kilodaltons of PAg, which was seen in untreated PAg and WC, shifted to a position with a molecular size of ca. 20 kilodaltons after heat treatment of PAg at 80 degrees C for 30 min and WC at 100 degrees C for 30 min. In the enzyme-linked immunosorbent assay inhibition test with monoclonal antibody LW2 and a sonicated antigen of WC, the inhibition rate of PAg and WC to sonicated WC was reduced by heat treatment at 80 degrees C for 30 min and at 100 degrees C for 30 min, respectively. Agglutinating antibody-inducing activities and opsonin-inducing activities of PAg and WC in mice were reduced by heat treatment under the same conditions; these activities were assayed by a microscopic agglutination test and by chemical luminescence response in serum from immunized mice, respectively. Protective activity of heated PAg and heated WC in cyclophosphamide-pretreated mice agreed with the results of immunogenicity in mice. These results indicate that the Leptospira PAg is one of the important protective antigens and is altered by heat treatment at 80 degrees C.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka, Japan. PMID- 2332463 CU - 91 SO - J Clin Microbiol 1990 Apr;28(4):660-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 90223375 AU - Hesselink JW TI - [A safe system of urine collection in cows] LA - Dut MH - Animal MH - Cattle/*urine MH - English Abstract MH - Specimen Handling/methods/*veterinary PT - JOURNAL ARTICLE DA - 900516 DP - 1990 Apr 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 305-6 SB - M CY - NETHERLANDS IP - 7 VI - 115 JC - VRY AA - Author EM - 9007 AB - The usual method of sampling urine in cows involves the risk of ingestion of micro-organisms, particularly Leptospira hardjo. A simple system is described, in which this risk is reduced to a minimum. This system can also be used in sampling urine in mares. PMID- 2326782 TT - Een veilig systeem voor urine-afname bij de koe. EA - A SO - Tijdschr Diergeneeskd 1990 Apr 1;115(7):305-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 90219177 AU - Everard CO AU - Carrington DG AU - Korver H AU - Burke R AU - Everard JD AU - Gravekamp C TI - Leptospires in the whistling frog (Eleutherodactylus johnstonei) on Barbados. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Anura/immunology/*microbiology MH - Barbados MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900518 DP - 1990 Apr IS - 0022-5304 TA - J Trop Med Hyg PG - 140-5 SB - M CY - ENGLAND IP - 2 VI - 93 JC - KAV AA - Author EM - 9007 AB - Two groups of whistling frogs (Eleutherodactylus johnstonei) comprising 99 and 117 animals were examined for leptospiral infection. Group I animals were caught in 14 areas of Barbados, and Group II animals in seven areas of suburban Bridgetown. Leptospires were isolated from the kidneys or body fluid of six frogs in Group I and the kidneys of 3 frogs in Group II. Two of the Group I isolates died out; the others were identified as bajan (a new serovar in the Australis serogroup) (6) and bim (Autumnalis) (1). The macerated body tissues and fluid of Group I frogs were put into phosphate buffered saline and examined by the microscopic agglutination test using 22 antigens. The results were all negative. For the Group II frogs the methodology was altered; blood was collected onto filter paper discs and allowed to dry out before being agitated in PBS and examined by the MAT. 15/117 (12.8%) animals were positive at greater than or equal to 1:100 and 19 (16.2%) at greater than or equal to 1:50. The geometric mean titre was 179. Seventeen of the sera reacted predominantly to antigens in the Australis serogroup, and two to Pyrogenes on its own. The serological results reflected the identity of the isolates. Serovars of Australis are not known to cause illness on Barbados, but bim is the commonest cause of severe leptospirosis on the island. AD - Leptospira Laboratory, St Michael, Barbados. PMID- 2325195 CU - 91 SO - J Trop Med Hyg 1990 Apr;93(2):140-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 90208437 AU - Shpilberg O AU - Shaked Y AU - Maier MK AU - Samra D AU - Samra Y TI - Long-term follow-up after leptospirosis. LA - Eng MH - Acute Disease MH - Adolescence MH - Adult MH - Aged MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - Female MH - Follow-Up Studies MH - Headache/complications MH - Human MH - Leptospirosis/complications/*diagnosis MH - Male MH - Middle Age MH - Prognosis MH - Retrospective Studies MH - Uveitis/etiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900510 DP - 1990 Apr IS - 0038-4348 TA - South Med J PG - 405-7 SB - A SB - M SB - X CY - UNITED STATES IP - 4 VI - 83 JC - UVH AA - Author EM - 9007 AB - Human leptospirosis is an infectious disease that is a substantial problem in the Third World, but it can occur in developed countries as well. Survivors of the acute disease are considered to recover without sequelae, though little literature exists on long-term follow-up among these patients. Eleven patients, at an average of 22 years after acute leptospirosis, were reevaluated for possible delayed sequelae. Results showed that liver and renal disease had resolved, but headache and ophthalmic sequelae persisted. Even though the number of patients involved in this study is small, it appears that the eyes, particularly the anterior chambers, may be the site of continuing morbidity after acute human leptospirosis. The pathogenesis for persistent headache is not known. AD - Rusinow Department of Internal Medicine C, Chaim Sheba Medical Center, Tel Hashomer, Israel. PMID- 2321070 CU - 91 SO - South Med J 1990 Apr;83(4):405-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 91112071 AU - Kondratenko VN AU - Dremliuga VI TI - [The natural foci of leptospirosis in different topographic-geographic zones of the Bukovinan Carpathians] LA - Rus MH - Animal MH - *Disease Reservoirs/veterinary MH - Disease Vectors MH - Geography MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Rodent Diseases/epidemiology MH - Rodentia MH - Ukraine/epidemiology MH - Weil's Disease/epidemiology/veterinary PT - JOURNAL ARTICLE DA - 910225 DP - 1990 Apr IS - 0049-6804 TA - Vrach Delo PG - 116-7 CY - USSR IP - 4 JC - XLS EM - 9105 PMID- 2275147 TT - Prirodnaia ochagovost' leptospiroza v razlichnykh landshaftno- geograficheskikh zonakh Bukovinskogo Prikarpat'ia. SO - Vrach Delo 1990 Apr;(4):116-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [2 protein links] [1 nucleotide link] [202 medline neighbors] UI - 90376065 AU - Richaud C AU - Margarita D AU - Baranton G AU - Saint Girons I TI - Cloning of genes required for amino acid biosynthesis from Leptospira interrogans serovar icterohaemorrhagiae. LA - Eng MH - Amino Acids/*biosynthesis MH - Bacterial Typing Techniques MH - Cloning, Molecular MH - DNA, Bacterial/genetics MH - Escherichia coli/genetics MH - *Genes, Bacterial MH - Genetic Complementation Test MH - Leptospira interrogans/classification/*genetics MH - Leucine/biosynthesis/genetics MH - Mutation MH - Nucleic Acid Hybridization MH - Proline/biosynthesis/genetics MH - Restriction Mapping MH - Support, Non-U.S. Gov't RN - 0 (Amino Acids) RN - 0 (DNA, Bacterial) RN - 147-85-3 (Proline) RN - 7005-03-0 (Leucine) PT - JOURNAL ARTICLE DA - 901016 DP - 1990 Apr IS - 0022-1287 TA - J Gen Microbiol PG - 651-6 SB - M CY - ENGLAND VI - 136 ( Pt 4) JC - I87 AA - Author EM - 9012 AB - Leptospira interrogans belongs to a large family of important pathogens, which is part of the order Spirochaetales, a distinct group of eubacteria. In order to obtain a better understanding of the genetic organization of this species, we have constructed a DNA library of the serovar icterohaemorrhagiae, using the Escherichia coli vector pUC13. We have isolated Leptospira DNA fragments containing the genetic information required to complement strains of E. coli with defects in proline and leucine biosynthesis. While a 3.9 kb fragment which complemented proA also complemented proB, a 15 kb fragment complementing leuB could not complement other leu mutations. The L. interrogans origin of the cloned DNA fragments was confirmed by DNA-DNA hybridization. The hydridization was specific to the pathogenic species and was not seen with the saprophytic species L. biflexa. AD - Unite des Leptospires, Institut Pasteur, Paris, France. PMID- 2204676 CU - 92 SO - J Gen Microbiol 1990 Apr;136 ( Pt 4):651-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 91376298 AU - Lomar AV TI - Evaluation of the hemostasis in leptospirosis. LA - Eng LA - Por MH - *Hemostasis MH - Human MH - Leptospirosis/*blood MH - Prospective Studies PT - JOURNAL ARTICLE DA - 911023 DP - 1990 Apr-Jun IS - 0037-8682 TA - Rev Soc Bras Med Trop PG - 127 CY - BRAZIL IP - 2 VI - 23 JC - RET EM - 9112 AD - Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brasil. PMID- 2104454 SO - Rev Soc Bras Med Trop 1990 Apr-Jun;23(2):127 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 91242738 AU - Knudtson WU AU - Fetters M TI - The effect of heat-inactivation on agglutinating antibody titers to Leptospira interrogans. LA - Eng MH - Agglutination Tests MH - Animal MH - Antelopes MH - Antibodies, Bacterial/*blood MH - Cattle MH - Goats MH - Heat MH - Horses MH - Leptospira interrogans/*immunology MH - Swine RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910702 DP - 1990 Apr IS - 1040-6387 TA - J Vet Diagn Invest PG - 149-50 SB - M CY - UNITED STATES IP - 2 VI - 2 JC - A2D EM - 9109 AD - US Department of Agriculture, Animal and Plant Health Inspection Service, Science and Technology, National Veterinary Services Laboratories, Ames, IA 50010. PMID- 2094439 CU - 91 SO - J Vet Diagn Invest 1990 Apr;2(2):149-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 90309437 AU - Falco Ferrer V AU - Fernandez de Sevilla Ribosa T TI - [Leptospirosis: a disease with multiorganic manifestations] LA - Spa MH - Human MH - Leptospira interrogans/isolation & purification MH - Weil's Disease/*complications/diagnosis/drug therapy/microbiology PT - JOURNAL ARTICLE DA - 900814 DP - 1990 Mar 31 IS - 0025-7753 TA - Med Clin (Barc) PG - 454-6 CY - SPAIN IP - 12 VI - 94 JC - LTQ EM - 9010 AD - Servicio de Medicina Interna, Unidad de Patologia Infecciosa, Hospital General Vall d'Hebron, Universidad Autonoma, Barcelona. PMID- 2366605 TT - Leptospirosis: una enfermedad con manifestaciones multiorganicas. SO - Med Clin (Barc) 1990 Mar 31;94(12):454-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 90318012 AU - Pupkevich-Diamant IaS AU - Gurfinkel' LR AU - Nisnevich EB TI - [Electrocardiographic changes in leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Aged MH - Case Report MH - Electrocardiography MH - English Abstract MH - Female MH - Heart/*physiopathology MH - Human MH - Leptospirosis/*physiopathology MH - Male MH - Middle Age MH - Weil's Disease/physiopathology PT - JOURNAL ARTICLE DA - 900820 DP - 1990 Mar IS - 0023-2149 TA - Klin Med (Mosk) PG - 82-6 CY - USSR IP - 3 VI - 68 JC - KW2 AA - Author EM - 9010 AB - The study involved 239 ECGs recorded in acute period of various leptospirosis forms. In 86.2% of cases there were changes evidencing impairment of neuromuscular system and atrial (76.6%) or ventricular (61.9%) conduction. The above cardiac manifestations arise early, have peculiar characteristic features. The discussion covers their patho- and morphogenesis, frequency of detection, necessary time-course ECG control over leptospirosis patients and convalescents. PMID- 2370763 TT - Elektrokardiograficheskie izmeneniia pri leptospiroze. EA - A SO - Klin Med (Mosk) 1990 Mar;68(3):82-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 90301620 AU - Mumford C AU - Dudley N AU - Terry H TI - Leptospirosis presenting as a flaccid paraplegia. LA - Eng MH - Case Report MH - Human MH - Kidney Diseases/etiology MH - Leptospirosis/complications/*diagnosis MH - Liver Diseases/etiology MH - Male MH - Middle Age MH - Paraplegia/*etiology MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 900808 DP - 1990 Mar IS - 0032-5473 TA - Postgrad Med J PG - 218-20 SB - M CY - ENGLAND IP - 773 VI - 66 JC - PFX AA - Author EM - 9010 AB - A fatal case of leptospirosis in a 64 year old farm worker is described. The dramatic neurological presentation with a rapidly evolving flaccid paraplegia associated with biochemical evidence of renal and hepatic dysfunction is discussed. Attention is drawn to the wide range of neurological symptoms reported in leptospirosis, and to the possibility that this infectious disease may present neurologically. AD - Department of Neurology, University Hospital, Queen's Medical Centre, Nottingham, UK. PMID- 2362889 SO - Postgrad Med J 1990 Mar;66(773):218-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 90263728 AU - Everard CO AU - Bennett S TI - Persistence of leptospiral agglutinins in Trinidadian survey subjects. LA - Eng MH - Adolescence MH - Adult MH - Agglutinins/*immunology/isolation & purification MH - Child MH - Demography MH - Epidemiologic Methods MH - Female MH - Follow-Up Studies MH - Human MH - Leptospira/*immunology/isolation & purification/pathogenicity MH - Leptospirosis/*epidemiology/immunology/physiopathology MH - Male MH - Support, Non-U.S. Gov't MH - Trinidad and Tobago RN - 0 (Agglutinins) PT - JOURNAL ARTICLE DA - 900702 DP - 1990 Mar IS - 0392-2990 TA - Eur J Epidemiol PG - 40-4 SB - M CY - ITALY IP - 1 VI - 6 JC - ERE AA - Author EM - 9009 AB - Participants in a survey for leptospiral agglutinating antibodies undertaken in Trinidad, West Indies, in 1977-78, were further monitored for up to 5-and-a-half years. 52 individuals with a titre greater than or equal to 1:400 were matched for age, sex and occupation with seronegative subjects. They were re-bled twice (on average 2.38 and 4.84 years later), and changes of titre were noted. At the first follow- up, 78% of negative controls remained negative, and 22%, showed titre changes. Among the seropositive subjects, 47% showed a fall in titre, 38% showed no change, and in 15% the titre rose. New exposure rates between the original and first follow-up samples were 96/1,000 survey population per year in the controls, and 68/1,000 for the subjects with titres greater than or equal to 1:400. Between the first and second follow-up, 47% of the seropositive subjects lost titre, 40% showed no change, and 13% showed a rise in titre. These data demonstrate that although antibody titres may be maintained for a few years at the same level, or show a loss as is usually expected, about 8.3% of individuals in Trinidad may be infected/reinfected per year. The infection/reinfection rate is an important factor in the epidemiology of leptospirosis. AD - Leptospira Laboratory, Lower Collymore Rock, St. Michael, Barbados. PMID- 2344875 CU - 91 SO - Eur J Epidemiol 1990 Mar;6(1):40-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 90239918 AU - Edwards CN AU - Nicholson GD AU - Hassell TA AU - Everard CO AU - Callender J TI - Leptospirosis in Barbados. A clinical study. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Barbados/epidemiology MH - Female MH - Human MH - Leptospira canicola/*classification MH - Leptospira interrogans/*classification MH - Leptospirosis/complications/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Serotyping MH - Support, Non-U.S. Gov't PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - RANDOMIZED CONTROLLED TRIAL DA - 900606 DP - 1990 Mar IS - 0043-3144 TA - West Indian Med J PG - 27-34 CY - JAMAICA IP - 1 VI - 39 JC - XN4 AA - Author EM - 9008 AB - A 39-month clinical study of leptospirosis was undertaken at the Queen Elizabeth Hospital, Barbados. Eighty-eight patients had a confirmed diagnosis of the disease during the period. The major serogroups identified were autumnalis (including a new serovar bim), icterohaemorrhagiae, ballum and canicola. The majority of patients presented with jaundice (95%,) anorexia and headaches (85%), fever (76%) and conjunctival suffusion (54%). While abnormal creatinine levels were seen in 49% of patients on admission, only 16% were judged to have had renal failure. The urine to plasma urea ratio showed high sensitivity and specificity in the diagnosis of pre-renal azotemia. Cardiac arrhythmias and myocarditis occurred in 18% of patients and pericarditis in 6%. An elevated serum amylase was found in 65% of cases. The bilirubin level took 5.5 weeks to return to normal. Thrombocytopenia was shown not to be due to a disseminated intravascular coagulation, and a randomised trial of high dose penicillin did not reveal any benefit to jaundiced patients. The overall mortality during the study was 5.7%. AD - Department of Medicine, U.W.I., Queen Elizabeth Hospital, Barbados. PMID- 2333695 CU - 94 SO - West Indian Med J 1990 Mar;39(1):27-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 90235775 AU - Wernery U AU - Wernery R TI - [Seroepidemiologic studies of the detection of antibodies to Brucella, Chlamydia, Leptospira, BVD/MD virus, IBR/IPV virus and enzootic bovine leukosis virus (EBL) in dromedary mares (Camelus dromedarius)] LA - Ger MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/analysis MH - Brucellosis/epidemiology/*veterinary MH - *Camels MH - Chlamydia Infections/epidemiology/*veterinary MH - English Abstract MH - Female MH - Leptospirosis/epidemiology/*veterinary MH - United Arab Emirates/epidemiology MH - Virus Diseases/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 900605 DP - 1990 Mar IS - 0341-6593 TA - DTW Dtsch Tierarztl Wochenschr PG - 134-5 CY - GERMANY, WEST IP - 3 VI - 97 JC - ECT AA - Author EM - 9008 AB - Camels which are bred for the purpose of racing were tested serologically for 6 different animal diseases. The group were split into racing and breeding camels. The following results were achieved: Brucellosis, breeding camels 2%, racing camels 6.6%; Chlamydiosis 24%, 15%; Leptospirosis 2.5%, 5.6%; BVD/MD 9.2%, 3.6%. No antibodies were detected against IBR/IPV- and EBL-virus. The results are discussed under an epidemiological point of view. AD - Central Veterinary Research Laboratory Dubai (Vereinigte Arabische Emirate). PMID- 2331972 CU - 91 TT - Seroepidemiologische Untersuchungen zum Nachweis von Antikorpern gegen Brucellen, Chlamydien, Leptospiren, BVD/MD-, IBR/IPV- und Enzootischem Bovinen Leukosevirus (EBL) bei Dromedarstuten (Camelus dromedarius). EA - A SO - DTW Dtsch Tierarztl Wochenschr 1990 Mar;97(3):134-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 90234141 AU - Masuzawa T AU - Nakamura R AU - Hashiguchi Y AU - Shimizu T AU - Iwamoto Y AU - Morita T AU - Yanagihara Y TI - Immunological reactivity and passive protective activity of monoclonal antibodies against protective antigen (PAg) of Leptospira interrogans serovar lai. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Monoclonal/biosynthesis/*immunology/isolation & purification MH - Antigens, Bacterial/*immunology MH - Enzyme-Linked Immunosorbent Assay MH - Hamsters MH - Immune Sera/immunology MH - *Immunization, Passive MH - Leptospira interrogans/*immunology MH - Luminescence MH - Macrophages/immunology MH - Male MH - Mesocricetus MH - Mice MH - Opsonins/immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/*prevention & control RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Opsonins) RN - 0 (Immune Sera) PT - JOURNAL ARTICLE DA - 900604 DP - 1990 Mar IS - 0934-8840 TA - Zentralbl Bakteriol PG - 328-36 SB - M CY - GERMANY IP - 3 VI - 272 JC - BD7 AA - Author EM - 9008 AB - Monoclonal antibody (MAb) AG1 against the protective antigen (PAg) was produced and characterized. It had been extracted from Leptospira interrogans serovar lai by the chloroform-methanol-water method and was of glycolipid nature (23-30Kd). The fact that the PAg was a serogroup- specific antigen was shown by MAb AG1, because MAb AG1 agglutinated serovars of serogroup Icterohaemorrhagiae. Purified MAb LW2 and LW3 which are agglutinating antibodies of serovar lai and AG1 passively protected hamsters from leptospiral infection. Induction of the reactive oxygen intermediates by MAbs from peritoneal exudate macrophages of mice were observed in the chemical luminescence assay and the MAbs reacted with the PAg in the dot enzyme-linked immunosorbent assay. However, MAb LW4a against the genus-specific antigen present in the sub-surface of leptospiral cells did not show protective and reactive-oxygen-inducing activities; they reacted with the non-protective glycolipid antigen of low molecular weight (Fr I, 10- 15Kd) in the dot enzyme-linked immunosorbent assay. These results indicated that anti-PAg antibody exhibited opsonic activity against Leptospira and the production of reactive oxygens by macrophages led to leptospiricidal action as one of the defence mechanisms of the host against leptospiral infection. However, the antibody against the genus- specific glycolipid antigen may not be important for protection against leptospiral infection. AD - Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka, Japan. RO - M:CNR PMID- 2331299 LR - 970218 CU - 92 SO - Zentralbl Bakteriol 1990 Mar;272(3):328-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 90170110 AU - Thomas DD AU - Higbie LM TI - In vitro association of leptospires with host cells. LA - Eng MH - Animal MH - *Bacterial Adhesion MH - Cells, Cultured MH - Leptospira/*physiology/pathogenicity MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Swine MH - Virulence PT - JOURNAL ARTICLE DA - 900330 DP - 1990 Mar IS - 0019-9567 TA - Infect Immun PG - 581-5 SB - M SB - X CY - UNITED STATES IP - 3 VI - 58 JC - GO7 AA - Author EM - 9006 AB - Interactions of Leptospira interrogans with cultured endothelial and kidney epithelial cells were assayed by examining (i) cytoadherence of intrinsically radiolabeled leptospires to eucaryotic cell monolayers and (ii) penetration of leptospires through cell monolayers grown on polycarbonate filters in chemotaxis chambers. L. interrogans serovars attached to cultured cells in a dose- and time-dependent manner. Adherence was diminished following pretreatment of organisms with proteases, rabbit immune serum, or heat. When observed by scanning electron microscopy, most leptospires attached by both ends, rather than just one tip like Treponema pallidum. In penetration assays, 9.7% of added L. interrogans migrated through the monolayer-filter barrier, while only 0.3% of L. biflexa penetrated in the same time interval. Transmission electron microscopy revealed that organisms entered the host cell cytoplasm. These in vitro results indicate that leptospires have an invasive capacity that may be related to pathogenicity in vivo and suggest that further investigation of interactions with host cells may enhance knowledge of leptospiral virulence. AD - Department of Microbiology and Immunology, Bowman Gray School of Medicine, Wake Forest University Medical Center, Winston-Salem, North Carolina 27103. PMID- 2307512 SO - Infect Immun 1990 Mar;58(3):581-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 92237600 AU - Wakamatsu A AU - Pagano LS AU - Gayotto LC AU - Santos RT AU - Sakata EE AU - Kanamura CT AU - Candelori I AU - Pestana CB AU - Yasuda PH AU - Alves VA TI - [High resolution light microscopy: adaptation of the method and its use in the study of experimental leptospirosis in guinea pigs] LA - Por MH - Animal MH - Disease Models, Animal MH - English Abstract MH - Guinea Pigs MH - Kidney/*pathology MH - Liver/*pathology MH - Male MH - Microscopy/methods MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 920522 DP - 1990 Mar-Apr IS - 0041-8781 TA - Rev Hosp Clin Fac Med Sao Paulo PG - 47-52 CY - BRAZIL IP - 2 VI - 45 JC - S3L AA - Author EM - 9207 AB - Morphological lesions in parenchimal and mesenchimal structures of liver and kidney were studied in guinea-pigs experimentally infected with Leptospira interrogans serogroup icterohaemorrhagiae in comparison with a group of non-infected guinea-pigs. All specimens were submitted to conventional light microscopy as well as to high resolution light microscopy, in one micrometer sections of tissue embedded in glycolmethacrylate. High resolution light microscopy, applied for the first time in leptospirosis, was proved very useful, since it enabled us to visualize cellular structures in the same slide used for panoramic view. Cell cohesion, brush borders, pynocytotic vesicles and organellae distributions were parameters especially suitable for analysis at this low-cost, highly precise procedure in microscopy. AD - Divisoes de Patologia, Instituto Adolfo Lutz, Universidade de Sao Paulo. PMID- 2135358 TT - Microscopia optica de alta resolucao: adaptacao do metodo e sua aplicacao ao estudo da leptospirose experimental em cobaias. EA - A SO - Rev Hosp Clin Fac Med Sao Paulo 1990 Mar-Apr;45(2):47-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 92053754 AU - Zamora J AU - Riedemann S AU - Montecinos MI AU - Cabezas X TI - [Serological survey of human leptospirosis in a high risk population in Chile] LA - Spa MH - Adolescence MH - Adult MH - Aged MH - Agglutination Tests MH - Agricultural Workers' Diseases/diagnosis/*epidemiology/etiology MH - Animal MH - Chile/epidemiology MH - English Abstract MH - Health Surveys MH - Human MH - Leptospirosis/diagnosis/*epidemiology/etiology MH - Male MH - Middle Age MH - Risk Factors MH - Seroepidemiologic Methods MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 911211 DP - 1990 Mar IS - 0034-9887 TA - Rev Med Chil PG - 247-52 CY - CHILE IP - 3 VI - 118 JC - SHD AA - Author EM - 9202 AB - Two hundred and sixty five subjects with high risk works for leptospirosis were submitted to microscopic agglutination test for leptospira. 122 worked at animal farms, 71 in rice growing fields and 72 in slaughter houses. 30 control subjects were also tested. A total of 66 samples (22%) were positive, most of them with low titers. Percentage of positive reactions were higher for persons working in rice fields, followed by those working in slaughter houses and animal farms. The 21-40 year age group was most affected in all working sites. Serovars found most commonly were ichterohemorrhagic in rice field workers, hardjo and ballum in slaughter houses and pomona and hardjo in animal farms. AD - Instituto de Microbiologia, Facultad de Ciencias, Universidad Austral de Chile, Valdivia. PMID- 2131502 TT - Encuesta serologica de leptospirosis humana en ocupaciones de alto riesgo en Chile. EA - A SO - Rev Med Chil 1990 Mar;118(3):247-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 90267899 AU - Green AD AU - Busuttil W TI - Exotic disease in a traveller? A case of leptospirosis [letter] LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - *Travel PT - LETTER DA - 900712 DP - 1990 Mar IS - 0960-1643 TA - Br J Gen Pract PG - 123-4 CY - ENGLAND IP - 332 VI - 40 JC - ARK EM - 9009 PMID- 2112017 CU - 91 SO - Br J Gen Pract 1990 Mar;40(332):123-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 90286314 AU - Otani S TI - [Diagnosis of Weil's disease] LA - Jpn MH - Agglutination Tests/methods MH - Antibodies, Bacterial/analysis MH - Human MH - Leptospira interrogans/immunology/*isolation & purification MH - Weil's Disease/*diagnosis/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900720 DP - 1990 Feb IS - 0047-1852 TA - Nippon Rinsho PG - 450-3 CY - JAPAN VI - 48 Suppl JC - KIM EM - 9009 AD - Department of Applied Immunology, National Institute of Health. PMID- 2355564 CU - 91 SO - Nippon Rinsho 1990 Feb;48 Suppl:450-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 90278282 AU - Petchclai B AU - Srisarin A AU - Potha U AU - Hiranras S AU - Wongpaitoon V TI - Evaluation of two screening tests for human leptospirosis. LA - Eng MH - Hemagglutination Tests/*methods MH - Human MH - Latex Fixation Tests/*methods MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 900719 DP - 1990 Feb IS - 0125-2208 TA - J Med Assoc Thai PG - 64-7 CY - THAILAND IP - 2 VI - 73 JC - IZR AA - Author EM - 9009 AB - Leptospirosis is prevalent in Thailand but its diagnosis depends primarily on clinical awareness. Serodiagnosis is of great assistance in the diagnosis of leptospirosis but in Thailand microagglutination (MA) is the only serodiagnosis available. MA is not rapid and it is used mainly in the referent laboratory. In addition, its roles in early diagnosis are rarely available. Rapid screening serological test which is sensitive early in the infection is needed. Latex agglutination (LA), indirect hemagglutination (IHA) were developed and evaluated in 100 MA positive sera and 200 blood donors. Later on, IHA and LA were compared with MA in 30 patients with a clinical picture compatible with leptospirosis. IHA and LA had sensitivities of 94 and 98 per cent respectively in MA positive sera. The specificity of IHA and LA in 200 blood donors was 99 and 100 per cent respectively. The study in 30 patients showed that LA and IHA were definitely more sensitive than MA test in sera collected within two weeks after the onset of fever. LA is also one of the most rapid tests for leptospirosis. With either LA or IHA human leptospirosis will be diagnosed more readily and more accurately. AD - Department of Pathology, Ramanthibodi Hospital, Bangkok, Thailand. PMID- 2351901 SO - J Med Assoc Thai 1990 Feb;73(2):64-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 90261379 AU - Iagovkin EA AU - Kostina NI AU - Vachaev BF AU - Romantsova TP AU - Kondratenko VF AU - Bunin IE AU - Gol'denshtein ZA AU - Anan'ina IuV TI - [The improvement of immunobiological preparations against leptospirosis. An experimental study of a new concentrated purified vaccine against icterohemorrhagic leptospirosis for human immunization] LA - Rus MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacterial Vaccines/*immunology/isolation & purification/toxicity MH - Comparative Study MH - Disease Reservoirs MH - Drug Screening MH - English Abstract MH - Guinea Pigs MH - Hamsters MH - Human MH - *Immunization MH - Leptospira interrogans/*immunology MH - Mice MH - Rabbits MH - USSR MH - Weil's Disease/immunology/mortality/*prevention & control RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 900627 DP - 1990 Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 47-51 SB - M CY - USSR IP - 2 JC - Y9O AA - Author EM - 9008 AB - The findings of the study of immunological structure of the population in regions endemic for leptospirosis indicate that the immune status of humans makes it impossible to obtain titrated blood sera for the preparation of antileptospirosis immunoglobulin. The data obtained in the study of the immunobiological properties of a new concentrated vaccine against icterohemorrhagic leptospirosis show the possibility of using this vaccine for the immunization of donors with the aim of obtaining blood sera to be used as raw material for the production of immunobiological preparations. PMID- 2343683 CU - 91 TT - Sovershenstvovanie immunobiologicheskikh protivoleptospiroznykh preparatov. Eksperimental'noe izuchenie novoi kontsentrirovannoi ochishchennoi vaktsiny protiv ikterogemorragicheskogo leptospiroza dlia immunizatsii liudei. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1990 Feb;(2):47-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 90265955 AU - Perolat P AU - Grimont F AU - Regnault B AU - Grimont PA AU - Fournie E AU - Thevenet H AU - Baranton G TI - rRNA gene restriction patterns of Leptospira: a molecular typing system. LA - Eng MH - *Bacterial Typing Techniques MH - *Chromosome Mapping MH - DNA MH - Leptospira/*classification/genetics MH - Leptospira interrogans/classification/genetics MH - Nucleic Acid Hybridization MH - Restriction Mapping MH - RNA, Ribosomal/*genetics RN - 0 (RNA, Ribosomal) RN - 9007-49-2 (DNA) PT - JOURNAL ARTICLE DA - 900705 DP - 1990 Feb IS - 0923-2508 TA - Res Microbiol PG - 159-71 SB - M CY - FRANCE IP - 2 VI - 141 JC - R6F AA - Author EM - 9009 AB - A total of 67 serovar reference strains and 7 isolates belonging to the genus Leptospira were characterized by ribosomal ribonucleic acid (rRNA) gene restriction patterns. Fifty patterns were observed. Strains belonging to different genomic species always gave different patterns. However, genomic species were subdivided into several patterns. Forty- three serovars gave a specific pattern. Some serovars could not be separated by rRNA gene restriction patterns: strains of serovars icterohaemorrhagiae, copenhageni, lai, pyrogenes and jalna gave pattern 1; serovars birkini, mankarso and wolffi gave pattern 4; serovars canicola, gem, hebdomadis, pomona and hardjo (strain hardjoprajitno) gave pattern 12; serovars valbuzzi and zanoni gave pattern 14; serovars jonsis, malaya and sumneri gave pattern 16; serovars arborea, ballum, castellonis and kenya gave pattern 35; and serovars borincana and shermani gave pattern 43. These data provide the bases for a molecular typing system for the genus Leptospira. AD - Unite des Leptospires, WHO Collaborating Centre for Leptospirosis, Paris. PMID- 2189169 CU - 92 SO - Res Microbiol 1990 Feb;141(2):159-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 90261388 AU - Pupkevich-Diamant IaS TI - [Debatable and unresolved questions in the epidemiology, pathogenesis, clinical picture, classification and nomenclature of leptospirosis] LA - Rus MH - Human MH - Leptospira/classification MH - Leptospirosis/classification/diagnosis/*epidemiology/etiology MH - *Nomenclature MH - Serotyping MH - USSR/epidemiology MH - Weil's Disease/classification/diagnosis/epidemiology/etiology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 900627 DP - 1990 Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 96-105 SB - M CY - USSR IP - 2 JC - Y9O EM - 9008 RF - 51 PMID- 2188470 CU - 90 TT - Nekotorye spornye i nereshennye voprosy epidemiologii, patogeneza, kliniki, klassifikatsii i nomenklatury leptospiroza. SO - Zh Mikrobiol Epidemiol Immunobiol 1990 Feb;(2):96-105 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 90218014 AU - Masuzawa T AU - Matsumoto T AU - Nakamura R AU - Suzuki R AU - Shimizu T AU - Yanagihara Y TI - Protective activity of glycolipid antigen against infection by Leptospira interrogans serovar canicola. LA - Eng MH - Animal MH - Antigens, Bacterial/*immunology/isolation & purification MH - Chromatography, Thin Layer MH - Cyclophosphamide MH - Electrophoresis, Polyacrylamide Gel MH - Glycolipids/*immunology/isolation & purification MH - Hamsters MH - Immunoenzyme Techniques MH - Leptospira canicola/*immunology MH - Leptospirosis/*prevention & control MH - Male MH - Mesocricetus MH - Mice MH - Mice, Inbred BALB C MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (Glycolipids) RN - 50-18-0 (Cyclophosphamide) PT - JOURNAL ARTICLE DA - 900521 DP - 1990 Feb IS - 0022-1287 TA - J Gen Microbiol PG - 327-30 SB - M CY - ENGLAND VI - 136 ( Pt 2) JC - I87 AA - Author EM - 9007 AB - A protective glycolipid antigen (PAg) was extracted from Leptospira interrogans serovar canicola with chloroform/methanol/water (1:2:0.8, by vol.) and partially purified by silica gel column chromatography. The PAg elicited a protective response in hamsters and in cyclophosphamide-treated mice subsequently challenged with homologous Leptospira. The PAg band was detected as a single smear-like band, corresponding to a protein of 23-30 kDa, by silver-staining in SDS- PAGE. In immunoblots, this band reacted with a monoclonal antibody, A5, which agglutinated serovar canicola and recognized a serovar-specific antigen. Furthermore, the PAg did not migrate on silica gel TLC, but was detected at the origin as a ninhydrin- and naphthol-positive spot. This suggests that PAg is a hydrophilic molecule with a carbohydrate chain that contains amino groups, possibly as amino sugars. AD - Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka, Japan. PMID- 2182771 CU - 92 SO - J Gen Microbiol 1990 Feb;136 ( Pt 2):327-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [203 medline neighbors] UI - 90221824 AU - Fukunaga M AU - Horie I AU - Okuzako N AU - Mifuchi I TI - Nucleotide sequence of a 16S rRNA gene for Leptospira interrogans serovar canicola strain Moulton. LA - Eng MH - Base Sequence MH - DNA, Ribosomal/genetics MH - *Genes, Structural, Bacterial MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - RNA, Ribosomal/*genetics MH - RNA, Ribosomal, 16S/*genetics RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Ribosomal) RN - 0 (RNA, Ribosomal, 16S) PT - JOURNAL ARTICLE DA - 900523 DP - 1990 Jan 25 IS - 0305-1048 TA - Nucleic Acids Res PG - 366 SB - M SB - X CY - ENGLAND IP - 2 VI - 18 JC - O8L EM - 9007 AD - University of Fukuyama, Faculty of Pharmacy and Pharmaceutical Science, Hiroshima, Japan. PMID- 2326171 CU - 93 SI - GENBANK/X17547 SO - Nucleic Acids Res 1990 Jan 25;18(2):366 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 90207079 AU - Carter H TI - Common zoonoses. LA - Eng MH - Animal MH - Bites and Stings/complications MH - Cats MH - Cattle MH - Dogs MH - Human MH - Leptospirosis/transmission MH - Ornithosis/transmission MH - Toxocariasis/transmission MH - *Zoonoses/prevention & control PT - JOURNAL ARTICLE DA - 900507 DP - 1990 Jan 15 IS - 0032-6518 TA - Practitioner PG - 49-51 CY - ENGLAND IP - 1481 VI - 234 JC - PHQ EM - 9007 RO - M:MWS PMID- 2320547 LR - 900613 SO - Practitioner 1990 Jan 15;234(1481):49-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 90113985 AU - Chappel RJ AU - Prime RW AU - Cutler RS AU - Jones RT AU - Millar BD AU - Adler B TI - Antileptospiral antibodies in Australian pig farmers [letter] LA - Eng MH - Animal MH - *Animal Husbandry MH - Antibodies, Bacterial/*analysis MH - Australia MH - Human MH - Leptospira interrogans/*immunology MH - Swine RN - 0 (Antibodies, Bacterial) PT - LETTER DA - 900214 DP - 1990 Jan 15 IS - 0025-729X TA - Med J Aust PG - 105 SB - M SB - X CY - AUSTRALIA IP - 2 VI - 152 JC - M26 EM - 9004 PMID- 2296221 CU - 91 SO - Med J Aust 1990 Jan 15;152(2):105 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 90131040 AU - Lindenmayer J AU - Weber M AU - Bryant J AU - Marquez E AU - Onderdonk A TI - Comparison of indirect immunofluorescent-antibody assay, enzyme-linked immunosorbent assay, and Western immunoblot for the diagnosis of Lyme disease in dogs. LA - Eng MH - Animal MH - Antibodies, Bacterial/isolation & purification MH - Blotting, Western MH - Borrelia burgdorferi/immunology MH - Comparative Study MH - Dog Diseases/*diagnosis/immunology MH - Dogs MH - Enzyme-Linked Immunosorbent Assay MH - Evaluation Studies MH - False Positive Reactions MH - Fluorescent Antibody Technique MH - Immunologic Tests/*veterinary MH - Lyme Disease/diagnosis/immunology/*veterinary MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900307 DP - 1990 Jan IS - 0095-1137 TA - J Clin Microbiol PG - 92-6 SB - M CY - UNITED STATES IP - 1 VI - 28 JC - HSH AA - Author EM - 9005 AB - Enzyme-linked immunosorbent assay (ELISA), indirect immunofluorescent- antibody assay (IFA), and Western immunoblot were used to test serum samples from 128 dogs for the presence of antibody to Borrelia burgdorferi. Sera included 72 samples from dogs suspected of having Lyme disease, 32 samples from dogs residing in areas in which Lyme disease was not considered endemic, and 24 samples from dogs with clinical and serologic evidence of immune-mediated disease (n = 10), Rocky Mountain spotted fever (n = 5), or leptospirosis (n = 9). Results of Western immunoblotting were used as the standard against which performances of ELISA and IFA were measured. ELISA was significantly more sensitive than IFA (84.8 versus 66.7%), although both tests were equally specific (93.5%). Eight samples that were positive by Western immunoblot were simultaneously negative by ELISA and IFA. Of these eight, four were from dogs suspected of having immune-mediated disease, two were from dogs suspected of having leptospirosis, and two were from dogs suspected of having Lyme disease. These results may indicate that sera from dogs with immune-mediated disease, and to a lesser extent sera from those with leptospirosis, cross-react with B. burgdorferi antigens. Alternatively, Western immunoblot results may not truly reflect Lyme disease status, particularly in the case of dogs with immune-mediated diseases. At present, however, the use of Western immunoblotting as a diagnostic standard for dogs offers the best alternative to a clinical definition of disease. AD - Division of Laboratories, Tufts University School of Veterinary Medicine, Jamaica Plain, Massachusetts 02130. PMID- 2405018 CU - 91 SO - J Clin Microbiol 1990 Jan;28(1):92-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 90301184 AU - Seguro AC AU - Lomar AV AU - Rocha AS TI - Acute renal failure of leptospirosis: nonoliguric and hypokalemic forms. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Female MH - Furosemide/therapeutic use MH - Human MH - Hypokalemia/etiology MH - Kidney Failure, Acute/classification/*etiology/metabolism MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Oliguria/drug therapy/etiology MH - Potassium/blood/urine MH - Sodium/urine MH - Support, Non-U.S. Gov't RN - 54-31-9 (Furosemide) RN - 7440-09-7 (Potassium) RN - 7440-23-5 (Sodium) PT - JOURNAL ARTICLE DA - 900806 DP - 1990 IS - 0028-2766 TA - Nephron PG - 146-51 SB - M CY - SWITZERLAND IP - 2 VI - 55 JC - NW8 AA - Author EM - 9010 AB - Acute renal failure induced by leptospirosis was studied in 56 patients. A higher frequency of nonoliguric renal failure was observed with lower morbidity and mortality rates than in oliguric forms. In addition, 45% of the patients in this series were hypokalemic, and no hyperkalemic patients were seen. A prospective study in 11 patients showed an initially elevated urinary fractional potassium excretion that fell simultaneously with the high urinary fractional sodium excretion and the urinary K/Na ratio, suggesting an increased distal potassium secretion due to an increased distal sodium delivery consequent to functional impairment of the proximal reabsorption of sodium. AD - Hospital Emilio Ribas SP, Brasil. PMID- 2362627 CU - 90 SO - Nephron 1990;55(2):146-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 90295561 AU - Maffei C AU - Di Stanislao F AU - Renga G TI - Epidemics and the media: an Italian experience. LA - Eng MH - *Disease Outbreaks MH - Human MH - Italy/epidemiology MH - Leptospirosis/epidemiology MH - Mass Behavior MH - *Newspapers MH - *Public Relations PT - JOURNAL ARTICLE DA - 900727 DP - 1990 Jan IS - 0033-3506 TA - Public Health PG - 33-5 CY - ENGLAND IP - 1 VI - 104 JC - QI7 EM - 9010 AD - Institute of Hygiene, University of Ancona Medical School, Italy. PMID- 2359818 SO - Public Health 1990 Jan;104(1):33-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 90273228 AU - Komnova ZD AU - Beliak GM TI - [Clinico-morphologic characteristics of leptospirosis with hemorrhagic syndrome] LA - Rus MH - Adult MH - Aged MH - English Abstract MH - Hepatorenal Syndrome/etiology/pathology MH - Human MH - Kidney Failure, Acute/etiology/pathology MH - Male MH - Middle Age MH - Multiple Organ Failure/etiology/pathology MH - Shock, Septic/etiology/pathology MH - Viscera/pathology MH - Weil's Disease/complications/*pathology PT - JOURNAL ARTICLE DA - 900711 DP - 1990 IS - 0038-5077 TA - Sov Med PG - 10-3 CY - USSR IP - 1 JC - UW7 AA - Author EM - 9009 AB - Infectious toxic shock, acute renal and acute hepatorenal insufficiency are the principal morphoclinical syndromes in malignant forms of icterohemorrhagic leptospirosis. The major complications of acute renal and hepatorenal failure are pyoseptic involvements of the lungs, heart, and pancreas. Direct or indirect signs of the DIC syndrome and intravascular platelet aggregation are characteristic of all the principal clinical syndromes of malignant forms of leptospirosis. PMID- 2349504 CU - 90 TT - Kliniko-morfologicheskaia kharakteristika leptospiroza s gemorragicheskim sindromom. EA - A SO - Sov Med 1990;(1):10-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 90183763 AU - Waldmann KH TI - [Progression and control of leptospirosis in a sow herd] LA - Ger MH - Animal MH - Disease Outbreaks/prevention & control/*veterinary MH - English Abstract MH - Female MH - Leptospirosis/epidemiology/prevention & control/*veterinary MH - Swine MH - Swine Diseases/*epidemiology/prevention & control PT - JOURNAL ARTICLE DA - 900426 DP - 1990 Jan IS - 0341-6593 TA - DTW Dtsch Tierarztl Wochenschr PG - 39-42 CY - GERMANY, WEST IP - 1 VI - 97 JC - ECT AA - Author EM - 9006 AB - After a short review about etiology, epidemiology, clinical symptoms, diagnosis and therapy of leptospirosis the course and therapy of an acute leptospirosis outbreak in a breeding herd with nearly 240 sows is described. The microscopic agglutination test (MAT) served for diagnosis and was most reliable for estimation the actually stage of infection when used twice with an interval of several weeks. As causative agent serovar L. pomona was identified, whereby cross- reactions were seen to serovars L. grippotyphosa, L. bratislava and L. copenhageni. Therapy of all animals with Terramycin/LA (Pfizer) at three times with intervals of five days and doses of 20 mg oxytetracycline/kg b.w. distinctly reduced the incidence of abortion and stillborn or mummified pigs. Local irritations, relative to the intramuscular administration of oxytetracycline, mostly were low-graded and temporary. For the next months acute infections could not be registered. Probably due to infections from leptospires-reservoirs, maintained by numerous existing mice and puddles on the pasture-ground, leptospirosis occurred again six months later. Only another antibiotic therapy of the whole herd and simultaneous eradication of rodents as well as closing the pasture led to a long-termed control of leptospirosis in this herd. AD - Klinik fur kleine Klauentiere und forensische Medizin und Ambulatorischen Klinik der Tierarztlichen Hochschule Hannover. PMID- 2311529 TT - Verlauf und Bekampfung der Leptospirose in einem Sauenbestand. EA - A SO - DTW Dtsch Tierarztl Wochenschr 1990 Jan;97(1):39-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 90163176 AU - Bercovich Z AU - Taaijke R AU - Bokhout BA TI - Evaluation of an ELISA for the diagnosis of experimentally induced and naturally occurring Leptospira hardjo infections in cattle. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Specificity MH - Antigens, Bacterial/immunology MH - Cattle MH - Cattle Diseases/*diagnosis MH - Comparative Study MH - *Enzyme-Linked Immunosorbent Assay MH - Leptospira/immunology MH - Leptospirosis/diagnosis/*veterinary MH - Predictive Value of Tests RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 900321 DP - 1990 Jan IS - 0378-1135 TA - Vet Microbiol PG - 255-62 SB - M CY - NETHERLANDS IP - 3 VI - 21 JC - XBW AA - Author EM - 9005 AB - An enzyme-linked immunosorbent assay (ELISA) for the diagnosis of Leptospira interrogans serovar hardjo (hardjo) infection in cattle was compared with the microscopic agglutination test (MAT). Glutardialdehyde was used in the ELISA to couple sonicated hardjo antigen to the microtiter plate. Mouse monoclonal anti-bovine IgG1 coupled to peroxidase was used as conjugate. Sera from calves experimentally inoculated with hardjo reacted positively in the MAT as early as 10 days after inoculation; these sera did not react positively in the ELISA until 25 days after the first inoculation. Positive and negative field sera from 704 adult cattle on 90 farms were examined by the MAT and the ELISA; a 90% correlation between the two tests was demonstrated. Eighty-six sera from calves inoculated with four Leptospira serogroups other than hardjo and 227 field sera from adult cattle with naturally occurring leptospirosis other than hardjo were examined by the ELISA. Fewer than 1% of these heterologous sera reacted with hardjo antigen in the ELISA. We concluded that the ELISA described in this report is an advantageous alternative to the MAT for diagnosing leptospirosis. AD - Central Veterinary Institute, Immunology Department, Lelystad, The Netherlands. PMID- 2305547 CU - 91 SO - Vet Microbiol 1990 Jan;21(3):255-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 90147490 AU - Brem S AU - Kopp H AU - Meyer P TI - [Leptospira antibody detection in dog serum in the years 1985 to 1988] LA - Ger MH - Animal MH - Antibodies, Bacterial/*analysis MH - Dog Diseases/*epidemiology MH - Dogs MH - English Abstract MH - Germany, West/epidemiology MH - Leptospira interrogans/*immunology MH - Prevalence MH - Weil's Disease/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900302 DP - 1990 Jan 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 6-8 CY - GERMANY, WEST IP - 1 VI - 103 JC - 9Q8 AA - Author EM - 9005 AB - In 1985-1988, 993 serum samples of dogs from Southern Bavaria and 408 samples from Northern Bavaria and from several Lands of the Federal Republic of Germany were tested for antibodies against the serovars canicola, icterohaemorrhagiae, grippotyphosa, bratislava, pomona, saxkoebing, sejroe and hardjo by using the microscopic agglutination test (MAT). 683 seras (48.75%) out of altogether 1401 samples showed a reaction against one up to seven serovars. The mostly low canicola- and icterohaemorrhagiae titers, having been proved in over 30% of the samples, can be put down to the fact, that usually the dogs had been vaccinated. Most frequently titers were found with the serovars grippotyphosa and bratislava--in Southern Bavaria 28.3%, in Northern Bavaria and other Lands of the Federal Republic of Germany 18.6%. The prevalence of titers against serovar saxkoebing, with or without a reaction against other serovars out of homologous and heterologous serogroups, reach up to 3.2% in sendings coming from Southern Bavaria and in other sendings up to 6.1%. AD - Landesuntersuchungsamt fur das Gesundheitswesen Sudbayern. PMID- 2302159 CU - 91 TT - Leptospirenantikorpernachweis aus Hundeseren in den Jahren 1985 mit 1988. EA - A SO - Berl Munch Tierarztl Wochenschr 1990 Jan 1;103(1):6-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 91153638 AU - Sebek Z AU - Vlcek M TI - [Small mammals as leptospirosis carriers on waste dumps] LA - Ger MH - Animal MH - Antibodies, Bacterial/*isolation & purification MH - Czechoslovakia MH - *Disease Reservoirs MH - English Abstract MH - Leptospira/*immunology MH - Leptospirosis/immunology/veterinary MH - *Refuse Disposal MH - Rodentia/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910411 DP - 1990 IS - 0300-807X TA - Geogr Med PG - 61-76 SB - M CY - HUNGARY VI - 20 JC - FN9 AA - Author EM - 9106 AB - In 1980-1986 the authors examined 2,720 small mammals (17 species) from six dumps of wastes in South-Bohemia serologically for leptospirosis. 397 small mammals from the agglomeration of Ceske Budejovice and 1,399 from four characteristic biotops in the valley of the river Vltava in South-Bohemia were investigated for a comparison. In small mammals from the dump of wastes at Ceske Budejovice antibodies against L. grippotyphosa were detected in 4.9%, against the serovars from the serogroup Sejroe in 2.6% and against L. icterohaemorrhagiae in 0.1%. In other five dumps of wastes only L. grippotyphosa antibodies were ascertained in small mammals, namely from 1.6% to 6.7%. In the agglomeration of the town Ceske Budejovice small mammals were positive in 4.0%, also for L. grippotyphosa only, in seven localities in the valley of the river Vltava with the same serovar in an average of 2.3%, with sorex-jalna in 0.1%. AD - Parasitologisches Institut der Tschechoslowakischen Akademie der Wissenschaften, Ceske Budejovice, CSFR. PMID- 2292388 CU - 91 TT - Kleinsauger als Leptospirosewirte auf den Mulldeponien. EA - A SO - Geogr Med 1990;20:61-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 91153016 AU - Andre-Fontaine G AU - Ganiere JP TI - New topics on leptospirosis. LA - Eng MH - Acute Disease MH - Animal MH - Chronic Disease MH - Dog Diseases/diagnosis/*epidemiology/prevention & control MH - Dogs MH - Human MH - Leptospirosis/diagnosis/*epidemiology/prevention & control PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 910410 DP - 1990 IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 163-8 SB - M CY - ENGLAND IP - 3 VI - 13 JC - DNN AA - Author EM - 9106 AB - In the United States, leptospirosis takes the second place in human diseases transmitted by animals. The clinical features of leptospirosis are very various in man and domestic animals by the nature of the serovar involved and the animal species infected. There are many epidemiological cycles of leptospirosis but environmental conditions are always important. AD - Ecole Nationale Veterinaire de Nantes, France. RF - 49 PMID- 2292185 SO - Comp Immunol Microbiol Infect Dis 1990;13(3):163-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 91110517 AU - Zaikov SV AU - Mazhbits MA AU - Panchenko GT AU - Fil' SF AU - Goncharova LI TI - [A case of leptospirosis simulating miliary pulmonary tuberculosis] LA - Rus MH - Case Report MH - Child MH - Diagnosis, Differential MH - Human MH - Leptospirosis/*diagnosis/radiography MH - Lung Diseases/*diagnosis/radiography MH - Male MH - Tomography, X-Ray MH - Tuberculosis, Pulmonary/*diagnosis/radiography PT - JOURNAL ARTICLE DA - 910222 DP - 1990 IS - 0032-9533 TA - Probl Tuberk PG - 70-2 CY - USSR IP - 9 JC - PQE EM - 9105 PMID- 2274517 TT - Sluchai leptospiroza, simuliruiushchii miliarnyi tuberkulez legkikh. SO - Probl Tuberk 1990;(9):70-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 91104674 AU - Park YK AU - Park SK AU - Rhee YK AU - Kang SK TI - Leptospirosis in Chonbuk Province of Korea in 1987. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Female MH - Human MH - Korea/epidemiology MH - Leptospirosis/complications/epidemiology/*pathology MH - Male MH - Middle Age MH - Time Factors PT - JOURNAL ARTICLE DA - 910228 DP - 1990 Jan TA - Korean J Intern Med PG - 34-43 CY - KOREA IP - 1 VI - 5 JC - AZI AA - Author EM - 9105 AB - Leptospirosis is a zoonosis with protean clinical manifestations. Its diagnosis requires a high index of suspicion and is confirmed by isolation of the organism or, more commonly, by serologic tests. In the fall of 1987, after severe flooding, we saw 93 patients with leptospirosis, confirmed by a microagglutination test. Thirteen percent of the patients had no clinical or laboratory findings except fever and headache, but the rest had mild to severe manifestations. Jaundice, renal failure, and aseptic meningitis were not common, but pulmonary symptoms, when present, were striking. The mortality rate was 5%. The main cause of death was asphyxiation due to massive hemoptysis from pulmonary hemorrhage and acute respiratory failure. AD - Department of Internal Medicine, Chonbuk National University, Medical School, Chonju, Korea. PMID- 2271509 SO - Korean J Intern Med 1990 Jan;5(1):34-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 91094666 AU - Fukunaga M AU - Masuzawa T AU - Okuzako N AU - Mifuchi I AU - Yanagihara Y TI - Linkage of ribosomal RNA genes in Leptospira. LA - Eng MH - DNA, Bacterial/metabolism MH - *Genes, Bacterial MH - Leptospira/*genetics MH - Leptospira interrogans/genetics MH - Linkage (Genetics) MH - RNA, Ribosomal/*genetics MH - RNA, Ribosomal, 16S/chemistry MH - RNA, Ribosomal, 23S/chemistry MH - RNA, Ribosomal, 5S/chemistry RN - 0 (DNA, Bacterial) RN - 0 (RNA, Ribosomal) RN - 0 (RNA, Ribosomal, 16S) RN - 0 (RNA, Ribosomal, 23S) RN - 0 (RNA, Ribosomal, 5S) PT - JOURNAL ARTICLE DA - 910214 DP - 1990 IS - 0385-5600 TA - Microbiol Immunol PG - 565-73 SB - M CY - JAPAN IP - 7 VI - 34 JC - MX7 AA - Author EM - 9104 AB - We determined the linkage of 16S, 23S, and 5S rRNA genes in several strains of Leptospira and Leptonema by DNA-DNA hybridization. Almost all the hybridizations in all leptospires used in these experiments gave two radioactive bands and the results strongly suggest that the number of the 16S and the 23S rRNA genes in those strains is two, respectively. In contrast with the larger rRNAs, the number of 5S rRNA gene was different. In the strains of leptospires, L. biflexa, which were non-parasitic, there are two genes for 5S rRNA, whereas only one gene for 5S rRNA is carried in L. interrogans, which were originally isolated as parasitic. Southern hybridization experiments suggest that those rRNA genes are interspersed on the leptospiral chromosome. AD - Faculty of Pharmacy and Pharmaceutical Science, University of Fukuyama, Hiroshima. PMID- 2266880 CU - 92 SO - Microbiol Immunol 1990;34(7):565-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 91027539 AU - Bahaman AR AU - Ibrahim AL AU - Stallman ND TI - Leptospira interrogans serovar unipertama isolated in Malaysia. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle/*microbiology MH - Cattle Diseases/*microbiology MH - Kidney/microbiology MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/*microbiology MH - Malaysia MH - Male MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 901205 DP - 1990 Jan IS - 0020-7713 TA - Int J Syst Bacteriol PG - 98-9 SB - M CY - UNITED STATES IP - 1 VI - 40 JC - AWO AA - Author EM - 9102 AB - A leptospiral isolate from a bovine kidney was found to be antigenically different from all previously recognized serovars of Leptospira interrogans based on the cross-agglutinin absorption test. The new serovar belongs to the Sejroe serogroup, and the name Leptospira interrogans serovar unipertama is proposed for it, with strain K2-1 as the reference strain. AD - Faculty of Veterinary Medicine and Animal Science, Universiti Pertanian Malaysia, Serdang, Selangor. PMID- 2223603 SO - Int J Syst Bacteriol 1990 Jan;40(1):98-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 91018817 AU - Ezeh AO AU - Addo PB AU - Adesiyun AA AU - Bello CS AU - Makinde AA TI - Serological prevalence of bovine leptospirosis in Plateau State, Nigeria. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/diagnosis/*epidemiology MH - Leptospirosis/diagnosis/epidemiology/*veterinary MH - Nigeria MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 901106 DP - 1990 IS - 0035-1865 TA - Rev Elev Med Vet Pays Trop PG - 505-8 CY - FRANCE IP - 4 VI - 42 JC - RSH AA - Author EM - 9101 AB - Serum samples obtained from 1.537 cattle in the 14 local government areas (LGAs) of Plateau State of Nigeria were screened for the presence of leptospiral antibodies using 13 serovars in a modified microscopic agglutination test (MAT). Two hundred and twenty-two (14.4 p.100) of the cattle tested had leptospiral antibody titres of 1:100 or higher to one or more of the test antigens. The prevalence rates of antibodies to individual serovars were: hardjo (35.6 p.100), pomona (11.7 p.100), pyrogenes (11.7 p.100), canicola (9.5 p.100), grippotyphosa (7.7 p.100), bratislava (5.9 p.100), icterohaemorrhagiae (5.9 p.100), ballum (4.5 p.100), autumnalis (3.6 p.100), bataviae (2.3 p.100) and tarassovi (1.8 p.100). The serological prevalence of bovine leptospirosis in the various local government areas of Plateau State of Nigeria differed significantly (P less than 0.05; X2). AD - National Veterinary Research Institute, Vom, Nigeria. PMID- 2218033 SO - Rev Elev Med Vet Pays Trop 1990;42(4):505-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 91014715 AU - Pereira MM AU - Andrade J TI - Human leptospirosis in a slum area in the city of Rio de Janeiro, Brazil--a serological and epidemiological study. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Antibodies, Bacterial/*analysis MH - Brazil/epidemiology MH - Child MH - Child, Preschool MH - Dogs MH - Female MH - Human MH - Infant MH - Infant, Newborn MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Poverty Areas MH - Rats MH - Seroepidemiologic Methods MH - Swine MH - Weil's Disease/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 901115 DP - 1990 Jan-Mar IS - 0074-0276 TA - Mem Inst Oswaldo Cruz PG - 47-52 SB - M CY - BRAZIL IP - 1 VI - 85 JC - MRY AA - Author EM - 9101 AB - A serologic survey was carried out on slum dwellers in the city of Rio de Janeiro. A total of 259 serum samples from male and female individuals of different age groups were tested for the presence of antileptospire antibodies by microagglutination. Prevalence data were analyzed in relation to the major risk factors present at the site, mainly represented by the presence of carrier animals and the occurrence of frequent floods. Of the samples tested, 25% reacted with antigens of different serogroups at titres ranging from 1:100 to 1:6400, with a predominance of titres less than or equal to 1:400; 35% of positive sera reacted with leptospirae of the Icterohaemorrhagiae serogroup. Reactions with Djasiman, Panama, Javanica, Canicola, Pyrogenes, Australis, Ballum, Sejroe, Bataviae, Grippotyphosa, Autumnalis and Cynopteri were also detected, though at lower frequencies. There was no statistically significant difference between sexes, but higher prevalence rates were found to be associated with increasing age. A focus of infection was characterized, in which social and economic factors contribute to the persistence of leptospirae by favoring the proliferation of the main reservoir. AD - Instituto Oswaldo Cruz, Departamento de Bacteriologia, Rio de Janeiro, RJ, Brasil. PMID- 2215233 CU - 91 SO - Mem Inst Oswaldo Cruz 1990 Jan-Mar;85(1):47-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 91215139 AU - Miller DA AU - Wilson MA AU - Beran GW TI - The effect of storage time on isolation of Leptospira interrogans from bovine kidneys. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Kidney/*microbiology MH - Leptospira interrogans/*isolation & purification MH - Refrigeration MH - Specimen Handling/*veterinary MH - Time Factors MH - Weil's Disease/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 910531 DP - 1990 Jan IS - 1040-6387 TA - J Vet Diagn Invest PG - 63-5 SB - M CY - UNITED STATES IP - 1 VI - 2 JC - A2D AA - Author EM - 9108 AB - Kidney tissues from 20 cattle infected with Leptospira interrogans serovars hardjo, pomona, or grippotyphosa were cultured on the day of slaughter and 3, 6, and 8 days later to examine the effect of storage time on the recovery of leptospires by conventional culture methods. Leptospires were isolated from 85% of infected bovine kidney tissues cultured on day 1, and from 95%, 90%, and 90% of kidney tissues stored in transport medium at 4 C for 3, 6, and 8 days, respectively, prior to inoculation of culture media. AD - National Veterinary Services Laboratories, US Department of Agriculture, Ames, IA 50010. PMID- 2090270 SO - J Vet Diagn Invest 1990 Jan;2(1):63-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 91199343 AU - Laporte P AU - Michault A AU - Galtier J AU - Lefait-Robin R AU - Aucher P AU - Baranton G TI - [Leptospirosis in Mayotte] LA - Fre MH - Adult MH - Animal MH - Disease Reservoirs MH - English Abstract MH - Female MH - Human MH - Incidence MH - Indian Ocean Islands/epidemiology MH - Leptospirosis/complications/*epidemiology MH - Male MH - Retrospective Studies MH - Tropical Climate PT - JOURNAL ARTICLE DA - 910517 DP - 1990 TA - Bull Soc Pathol Exot PG - 637-41 SB - M CY - FRANCE IP - 5 VI - 83 JC - BK9 AA - Author EM - 9107 AB - We have got 42 leptospirosis cases from 1984 to 1989, in a retrospective study. The annual incidence is now, in a very high level (3.8/10,000 pers.). This rapid increasing is function of new diagnostics facilities. The leptospirosis epidemiology is not different from anywhere else in tropical countries, but the complicated cases are an important problem in public health in the island. The actual development of collective hygienic equipment is indispensable for any progress. AD - Service de medecine, Hopital de Mamoudzou, Mayotte. RO - M:CNR PMID- 2085910 LR - 930519 TT - La leptospirose a Mayotte. EA - A SO - Bull Soc Pathol Exot 1990;83(5):637-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 91171962 AU - Fukunaga M AU - Mifuchi I AU - Yanagihara Y TI - Cloning of genes for a hemolytic factor of Leptospira interrogans serovar autumnalis strain Congo 21-543. LA - Eng MH - Cloning, Molecular MH - DNA, Bacterial/*analysis MH - *Genes, Bacterial MH - Hemolysin Factors/*genetics MH - Leptospira interrogans/*genetics/pathogenicity MH - Restriction Mapping MH - Transformation, Genetic RN - 0 (DNA, Bacterial) RN - 0 (Hemolysin Factors) PT - JOURNAL ARTICLE DA - 910422 DP - 1990 IS - 0385-5600 TA - Microbiol Immunol PG - 879-83 SB - M CY - JAPAN IP - 10 VI - 34 JC - MX7 AA - Author EM - 9106 AB - A DNA fragment encoding a hemolytic factor was cloned from the parasitic spirochete Leptospira interrogans serovar autumnalis strain Congo 21-543. Initial clones were isolated by screening a genomic library in pBR322 in Escherichia coli for hemolytic activity. Hemolytic activity was coded by a 4.5 kilobase BamHI-HindIII fragment. Southern hybridization with DNAs from other strains of Leptospira using this gene as a probe showed that DNAs from non-parasitic strains failed to hybridize with the probe, whereas those from all parasitic strains tested had the sequence which hybridize to the probe. AD - Faculty of Pharmacy and Pharmaceutical Science, University of Fukuyama. PMID- 2077368 CU - 92 SO - Microbiol Immunol 1990;34(10):879-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 90141607 TI - [Status leptospirosis/milker's fever in The Netherlands unchanged] LA - Dut MH - Animal MH - Antibodies, Bacterial/isolation & purification MH - Cattle MH - Cattle Diseases/*epidemiology MH - Female MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/*veterinary MH - Milk/immunology MH - Netherlands/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900306 DP - 1989 Dec 15 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 1252, 1255 SB - M CY - NETHERLANDS IP - 24 VI - 114 JC - VRY EM - 9005 PMID- 2617496 CU - 91 NI - A TT - Situatie leptospirose/melkerskoorts in Nederland stabiel. SO - Tijdschr Diergeneeskd 1989 Dec 15;114(24):1252, 1255 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 90201879 AU - Xie L AU - Dai BM AU - Jiang ZQ TI - [Comparative study of outer envelope protein and LPS of five strains of leptospires by SDS-PAGE and 2D-PAGE] LA - Chi MH - Bacterial Proteins/*analysis MH - Blotting, Western MH - Comparative Study MH - Electrophoresis, Gel, Two-Dimensional MH - Electrophoresis, Polyacrylamide Gel MH - English Abstract MH - Leptospira/*analysis/classification MH - Leptospira interrogans/analysis MH - Lipopolysaccharides/*analysis MH - Support, Non-U.S. Gov't RN - 0 (Bacterial Proteins) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 900510 DP - 1989 Dec IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 361-5 CY - CHINA IP - 4 VI - 20 JC - GEB AA - Author EM - 9007 AB - We applied SDS-PAGE, 2D-PAGE and Western blot to analyse the outer envelopes protein and LPS of five strains of leptospires. The work would lay foundations for taxonomy, the development of vaccination regimens and the elucidation of pathogenic mechanisms. The outer envelope proteins of leptospires were analyzed by SDS-PAGE and silver staining. We found that the protein profiles of the pathogenic leptospires were basically identical. A comparison of the protein profiles of the pathogenic L. with those exhibited by two nonpathogenic L. indicated that there was no obvious relationship between these organisms and any of the L. interrogans strains examined. The quantity of 21.5 kd protein of strain 017 was greater than that of strain 601 and 156. Approximately 200, 225, 238 distinct polypeptides were detected in the strain 017, 601 and 156 in 2D-PAGE by silver staining respectively. The profiles of 2D-PAGe showed obvious differences in pI. The pI of strain 017, 601 and 156 were mainly 6.68-7.4, 6.55-6.9, 5.85- 7.1 respectively. The 21.5 kd protein of strain 017 was made up of six polypeptides. Our immunoblots revealed that McAb (LB1) reacted with a 41 kd antigen, which was common to the three virulent leptospires tested. SDS-PAGE profiles of silver stained outer envelope LPS of pathogenic L. differed greatly from those of the nonpathogenic L. There was a distinct differences between strain Patoc I and 3055. Our studies showed that each of the five strains of leptospires possessed characteristic outer envelope LPS, which may be used to identify the genus, species and serovars of a strain of L. PMID- 2698369 CU - 91 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1989 Dec;20(4):361-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 90181005 AU - Cinco M AU - Banfi E AU - Stornello C AU - Campo F AU - Korver H TI - First human isolate of Leptospira interrogans as serovar bratislava in Italy. LA - Eng MH - Agglutination Tests MH - Animal MH - Human MH - Italy MH - Leptospira interrogans/classification/immunology/*isolation & purification MH - Mice MH - Mice, Inbred BALB C MH - Rabbits MH - Serotyping PT - JOURNAL ARTICLE DA - 900426 DP - 1989 Dec IS - 0920-8534 TA - FEMS Microbiol Immunol PG - 499-503 SB - M CY - NETHERLANDS IP - 8-9 VI - 1 JC - AO3 AA - Author EM - 9006 AB - A strain of Leptospira interrogans was isolated from a patient suffering from leptospirosis and was typed by the Cross Agglutination Absorption test using monoclonal antibodies prepared against different serovars of the Australis serogroup. This newly isolated strain belonged to serovar bratislava. It is the first reported isolation from man, in Italy, of Leptospira bratislava, thus supporting the emerging role of this serovar in human leptospirosis. AD - Istituto di Microbiologia dell'Universita di Trieste, Italy. PMID- 2627502 SO - FEMS Microbiol Immunol 1989 Dec;1(8-9):499-503 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 90174729 AU - Myburgh JG AU - Staley GP AU - van der Merwe SM TI - Serological evidence of bovine leptospirosis in Malawi. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/epidemiology/*immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Malawi/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900410 DP - 1989 Dec IS - 0030-2465 TA - Onderstepoort J Vet Res PG - 285-6 SB - M CY - SOUTH AFRICA IP - 4 VI - 56 JC - OI6 AA - Author EM - 9006 AB - Two hundred and seventy-five serum samples from cattle in Malawi were tested as a pilot survey for Leptospira antibody titres. Fifty-nine (21.4%) of the animals were positive for leptospirosis, while 35 (12.7%) animals reacted inconclusively. Titres to L. hardjo and L. pomona serovars were the most prevalent. Results are also discussed with reference to the areas where samples were collected. AD - Veterinary Research Institute, Onderstepoort. PMID- 2626265 CU - 91 SO - Onderstepoort J Vet Res 1989 Dec;56(4):285-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 90120240 AU - Bolin CA AU - Zuerner RL AU - Trueba G TI - Effect of vaccination with a pentavalent leptospiral vaccine containing Leptospira interrogans serovar hardjo type hardjo-bovis on type hardjo- bovis infection of cattle. LA - Eng MH - Animal MH - Antibody Formation MH - Bacterial Vaccines/administration & dosage/*immunology MH - Cattle MH - Cattle Diseases/*immunology MH - Comparative Study MH - Leptospira interrogans/classification/*immunology MH - Leptospirosis/immunology/*veterinary MH - Male MH - Serotyping/veterinary MH - Species Specificity MH - Vaccination/veterinary RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 900212 DP - 1989 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2004-8 SB - M CY - UNITED STATES IP - 12 VI - 50 JC - 40C AA - Author EM - 9004 AB - Effectiveness of 2 pentavalent leptospiral vaccines containing Leptospira interrogans serovar hardjo was evaluated for protection of steers from infection with serovar hardjo type hardjo-bovis. The hardjo component of 1 vaccine was prepared from serovar hardjo type hardjoprajitno. The hardjo component of the other vaccine was prepared from serovar hardjo type hardjo-bovis. Two steers were vaccinated once and 4 steers were vaccinated twice with the pentavalent vaccine containing type hardjoprajitno. Four steers were vaccinated once and 4 steers were vaccinated twice with the pentavalent vaccine containing type hardjo-bovis. Four steers were maintained as non-vaccinated controls. Steers given vaccine containing type hardjo-bovis developed higher mean serum microscopic agglutination titers against serovar hardjo than steers given vaccine containing hardjoprajitno. Six months after the first vaccination, all steers were challenge-exposed on 3 occasions by conjunctival instillation of 10(7) serovar hardjo type hardjo-bovis organisms, and on 1 occasion by conjunctival instillation of urine from a steer shedding hardjo-bovis. All control and all vaccinated steers became infected and shed serovar hardjo type hardjo- bovis in the urine. Lesions were detected in kidneys of 3 of 4 nonvaccinated control steers, 5 of 6 steers given hardjoprajitno vaccine, and 6 of 8 steers given hardjo-bovis vaccine. Leptospires were detected in kidneys of 4 of 4 control steers and 13 of 14 vaccinated steers. AD - Agricultural Research Service, National Animal Disease Center, Ames, IA 50010. PMID- 2610425 CU - 91 SO - Am J Vet Res 1989 Dec;50(12):2004-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 90108216 AU - Banfi E AU - Castagnari L AU - Cinco M TI - Serosurvey of Leptospira agglutinins among railway employees in the National Railway Compartments of Bologna and Venice. LA - Eng MH - Adult MH - Agglutinins/*analysis MH - Antibodies, Bacterial/*analysis MH - ABO Blood-Group System MH - Employment MH - Female MH - Hobbies MH - Housing MH - Human MH - Italy MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology/prevention & control MH - Male MH - Middle Age MH - Prevalence MH - Railroads MH - Risk Factors MH - Vaccination RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) RN - 0 (ABO Blood-Group System) PT - JOURNAL ARTICLE DA - 900209 DP - 1989 Dec IS - 0392-2990 TA - Eur J Epidemiol PG - 468-73 SB - M CY - ITALY IP - 4 VI - 5 JC - ERE AA - Author EM - 9004 AB - An epidemiological investigation was performed to evaluate the prevalence of anti-leptospiral agglutinins within a selected population: the railway workers of the Italian Railway Compartments of Bologna and Venice. Leptospira infection prevalence was found to be 10.38%, which represents the highest frequency ever reported in Italy. There was a significantly higher prevalence of agglutinins among the staff of the Railway Compartment of Venice. A clear prevalence of the bratislava serovar was registered, followed by the australis serovar and the icterohaemorrhagiae serovar. The influence of different kinds of railway work and that of supposed risk factors, such as hobbies and housing conditions, together with the influence of the ABO blood groups on the distribution of Leptospira agglutinins, are discussed. AD - Istituto di Microbiologia, Universita degli Studi di Trieste, Italy. PMID- 2606176 CU - 91 SO - Eur J Epidemiol 1989 Dec;5(4):468-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 90093942 AU - Donoghue AR AU - Schillhorn van Veen TW TI - Investigating cross-reactions between Leptospira and Borrelia [letter] LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Bacterial Vaccines/*immunology MH - Borrelia burgdorferi/*immunology MH - Cattle MH - Cross Reactions MH - Female MH - Leptospira/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - LETTER DA - 900202 DP - 1989 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1460, 1462 SB - M CY - UNITED STATES IP - 11 VI - 195 JC - HAV EM - 9004 PMID- 2599925 CU - 91 SO - J Am Vet Med Assoc 1989 Dec 1;195(11):1460, 1462 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 90078574 AU - Nielsen JN AU - Armstrong CH AU - Nielsen NC TI - Relationship among selected Leptospira interrogans serogroups as determined by nucleic acid hybridization. LA - Eng MH - Animal MH - Blotting, Southern MH - DNA Probes MH - DNA, Bacterial/*analysis MH - Leptospira interrogans/*classification/genetics MH - *Nucleic Acid Hybridization MH - Polymorphism, Restriction Fragment Length MH - Restriction Mapping MH - Serotyping MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 900112 DP - 1989 Dec IS - 0095-1137 TA - J Clin Microbiol PG - 2724-9 SB - M CY - UNITED STATES IP - 12 VI - 27 JC - HSH AA - Author EM - 9003 AB - Leptospiral DNAs from a variety of Leptospira interrogans serogroups of veterinary significance, as well as a nonpathogenic leptospira, were compared by Southern blot hybridization of EcoRI-digested genomic DNA. The serogroups examined could be assigned to one of three groups on the basis of the degree of cross-hybridization between genomic DNAs. Only a few restriction fragments hybridized between the three groups, and most of these were shown to contain ribosomal DNA. The restriction fragment length polymorphism observed among the intergroup hybridizations allowed differentiation among serogroups and, in some cases, serovars. Under the hybridization conditions used, no hybridization was observed between leptospiral DNA and Leptonema, Escherichia coli, or porcine DNA. AD - Department of Veterinary Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, Indiana 47907. PMID- 2574185 CU - 94 SO - J Clin Microbiol 1989 Dec;27(12):2724-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 90201880 AU - Qing GF AU - Dai BM AU - Wang YP TI - [Ultrastructural localization of leptospiral antigens by colloidal gold technique] LA - Chi MH - Animal MH - Antibodies, Monoclonal/diagnostic use MH - Antigens, Bacterial/*analysis MH - Cell Membrane/ultrastructure MH - English Abstract MH - Gold Colloid, Radioactive/*diagnostic use MH - Guinea Pigs MH - Leptospira interrogans/*immunology/ultrastructure MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Gold Colloid, Radioactive) PT - JOURNAL ARTICLE DA - 900510 DP - 1989 Dec IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 366-8 CY - CHINA IP - 4 VI - 20 JC - GEB AA - Author EM - 9007 AB - The rabbit anti-mouse antibodies were successfully labelled with colloidal gold. The distribution of leptospiral antigens in ultrastructure was researched with McAbs and labelled antibodies. It was found that colloidal gold particles were mainly distributed at the outer membrane of leptospiral strain O17 cells, which indicated that the antigens recognized by McAbs 1A7E7, and 2F9D4 were localized at the outer membrane of leptospiral cells. It was thought that colloidal technique would provide a method for research on the antigen distribution of leptospiral cells in ultrastructure. PMID- 2560988 CU - 93 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1989 Dec;20(4):366-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 90095099 AU - Liu YC AU - Dong GJ AU - Zhao YC TI - Preparation of diazotized polystyrene latex and its use in agglutination assays. LA - Eng MH - Agglutination Tests/*methods MH - Chemistry MH - Comparative Study MH - Human MH - Latex/*chemical synthesis/diagnostic use MH - Leptospirosis/diagnosis MH - Meningitis, Meningococcal/diagnosis MH - Microspheres MH - Polystyrenes/*chemical synthesis/diagnostic use RN - 0 (diazotized polystyrene latex) RN - 0 (Latex) RN - 0 (Polystyrenes) PT - JOURNAL ARTICLE DA - 900208 DP - 1989 Nov 30 IS - 0022-1759 TA - J Immunol Methods PG - 159-63 SB - M SB - X CY - NETHERLANDS IP - 2 VI - 124 JC - IFE AA - Author EM - 9004 AB - The preparation of this immunological latex consisted of the following steps: the synthesis of polystyrene, polynitrostyrene, polyaminostyrene and polystyrene diazonium salt latex. The quantities of emulsifier and initiator used in the synthesis of the polystyrene latex were much larger than those used in the conventional method. Reduction of the polynitrostyrene latex involved adding latex dropwise to a large excess of 6% sodium hydrosulphite-2 N potassium hydroxide solution with sodium lauryl benzene sulphonate as an emulsifier. When the mixture was heated at 70 degrees C for 4 h, the emulsion of polyaminostyrene was diazotized. The polystyrene diazonium salt latex obtained was capable of combining with 20-40% by weight of antibody protein. The immunopolystyrene diazonium latex reagents showed a positive agglutination reaction of 78-91% when mixed with serum from patients with leptospirosis and two other infectious diseases. The test, which can be completed within 3 min has been used to assay over 1200 patient samples. AD - Fourth Military Medical University, Xian, China. PMID- 2600424 CU - 92 SO - J Immunol Methods 1989 Nov 30;124(2):159-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [211 medline neighbors] UI - 90036654 AU - Fukunaga M AU - Mifuchi I TI - Unique organization of Leptospira interrogans rRNA genes. LA - Eng MH - Blotting, Southern MH - Cloning, Molecular MH - DNA, Ribosomal/genetics/isolation & purification MH - *Genes, Bacterial MH - Leptospira interrogans/*genetics MH - Nucleic Acid Hybridization MH - Restriction Mapping MH - RNA, Ribosomal/*genetics/isolation & purification RN - 0 (DNA, Ribosomal) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE DA - 891215 DP - 1989 Nov IS - 0021-9193 TA - J Bacteriol PG - 5763-7 SB - M CY - UNITED STATES IP - 11 VI - 171 JC - HH3 AA - Author EM - 9002 AB - We cloned Sau3AI fragments containing the rRNA genes for Leptospira interrogans serovar canicola strain Moulton in the BamHI site of lambda EMBL3 bacteriophage DNA. Physical maps of the fragments were constructed, and the locations of the rRNA genes were determined by Southern blot hybridization and S1 protection. Each fragment of the 23S or the 16S rRNA gene contained at least one copy of the 23S or the 16S sequence. Genomic hybridization showed that there were two genes for the 23S rRNA and the 16S rRNA but only one gene for the 5S rRNA on the chromosome of L. interrogans. The results revealed the important fact that each rRNA gene is located far from the other rRNA genes. Our findings, accordingly, also suggest that these rRNA genes are expressed independently in this organism. AD - Faculty of Pharmacy and Pharmaceutical Science, University of Fukuyama, Hiroshima, Japan. PMID- 2808297 CU - 92 SO - J Bacteriol 1989 Nov;171(11):5763-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 90124041 AU - Arimitsu Y AU - Moribayashi A AU - Goto N TI - Skin reaction to lipids from avirulent strain Shibaura of Leptospira interrogans serovar copenhageni. LA - Eng MH - Animal MH - Edema MH - Fatty Acids, Nonesterified/*immunology MH - Guinea Pigs MH - Hypersensitivity/*etiology MH - Leptospira interrogans/*immunology MH - Lipids/*immunology MH - Lipopolysaccharides/immunology MH - Neutrophils/immunology MH - Skin Tests MH - Weil's Disease/*etiology RN - 0 (Fatty Acids, Nonesterified) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 900308 DP - 1989 Nov IS - 0008-4166 TA - Can J Microbiol PG - 1009-14 SB - M CY - CANADA IP - 11 VI - 35 JC - CJ3 AA - Author EM - 9005 AB - Sonically disrupted cells from avirulent strain Shibaura of Leptospira interrogans serovar copenhageni induced a skin reaction characterized by infiltration of polymorphonuclear leukocytes (PMN) associated with some edema in guinea pigs. To determine the substance inducing infiltration of PMN, lipids of avirulent strain Shibaura were extracted with chloroform--methanol--water after washing with acetone. The lipids comprised 28% of the dry weight of the cell. When the lipids were further separated into water--methanol and chloroform fractions, the most severe PMN infiltration of all samples was seen in the skin inoculated with extract recovered from the chloroform fraction. Neutral and polar lipids were detected after thin-layer chromatography of the chloroform extract. Neutral lipids were detected as free fatty acids (FFA). Fatty acids contained in polar lipids were mainly palmitic acid and palmitoleic acid, whereas FFA comprised 66.5% oleic acid. Skin reactions consisting of marked edema with mild infiltration of PMN were elicited by FFA. There was no obvious difference between a commercially available FFA mixture and the FFA from avirulent strain Shibaura. These observations suggest that FFA may play some role in the pathogenesis of leptospirosis. AD - Department of Applied Immunology, National Institute of Health, Tokyo, Japan. PMID- 2611731 CU - 92 SO - Can J Microbiol 1989 Nov;35(11):1009-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 90121438 AU - Isogai E AU - Isogai H AU - Wakizaka H AU - Miura H AU - Kurebayashi Y TI - Chemiluminescence and phagocytic responses of rat polymorphonuclear neutrophils to leptospires. LA - Eng MH - Animal MH - Leptospira/*immunology MH - Leptospira interrogans/immunology/pathogenicity MH - Luminescence MH - Male MH - Neutrophils/*immunology/microbiology MH - Opsonins/immunology MH - *Phagocytosis MH - Rats MH - Virulence RN - 0 (Opsonins) PT - JOURNAL ARTICLE DA - 900228 DP - 1989 Nov IS - 0934-8840 TA - Zentralbl Bakteriol PG - 36-46 SB - M CY - GERMANY IP - 1 VI - 272 JC - BD7 AA - Author EM - 9005 AB - The interaction of leptospires with polymorphonuclear neutrophils (PMN) was examined by the luminol-dependent chemiluminescence (CL) test. Whole blood CL changed in relation to the stage of leptospiral infection both in susceptible (SUS) and resistant (RES) rats. The intensity of CL grew with an increasing number of leptospires in the blood. CL responses were observed in isolated PMN upon exposure to living leptospires. In contrast, the same bacteria, having been inactivated by formalin, did not stimulate PMN. A variation was found in the CL response by different living strains of Leptospira. The CL intensity was arranged as follows: L. illini greater than L. biflexa greater than L. interrogans avirulent strains greater than L. interrogans virulent strains. The CL response was markedly enhanced by an opsonization of leptospires. Specific opsonization was shown to increase the rate of phagocytosis of leptospires with relation to the CL response. AD - Department of Preventive Dentistry, School of Dentistry, Ishikari- Tobetsu, Japan. RO - M:CNR PMID- 2610812 LR - 970304 CU - 92 SO - Zentralbl Bakteriol 1989 Nov;272(1):36-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 90132127 AU - Kobayashi Y TI - [Infectious diseases and monoclonal antibodies] LA - Jpn MH - Antibodies, Monoclonal/biosynthesis/*diagnostic use MH - Encephalitis Virus, Japanese/classification/immunology MH - Encephalitis, Japanese/*diagnosis MH - Human MH - Leptospira/classification/immunology MH - Leptospirosis/*diagnosis MH - Rickettsia tsutsugamushi/classification/immunology MH - Scrub Typhus/*diagnosis MH - Serotyping RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 900228 DP - 1989 Nov IS - 0021-5384 TA - Nippon Naika Gakkai Zasshi PG - 1559-64 CY - JAPAN IP - 11 VI - 78 JC - IPZ EM - 9005 PMID- 2559132 CU - 93 SO - Nippon Naika Gakkai Zasshi 1989 Nov;78(11):1559-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 90079918 AU - Oh HM AU - Lee KS AU - Boey ML AU - Feng PH TI - Salmonella septicaemia mimicking leptospirosis. LA - Eng MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Human MH - Jaundice/etiology MH - Leptospirosis/*diagnosis MH - Male MH - Myositis/etiology MH - Paratyphoid Fever/complications/*diagnosis MH - Septicemia/*diagnosis/etiology PT - JOURNAL ARTICLE DA - 900125 DP - 1989 Nov IS - 0141-0768 TA - J R Soc Med PG - 690 SB - M CY - ENGLAND IP - 11 VI - 82 JC - JX1 EM - 9003 AD - Department of Medicine IV, Tan Tock Seng Hospital, Singapore. PMID- 2512387 CU - 91 SO - J R Soc Med 1989 Nov;82(11):690 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 90081581 AU - Skilbeck N TI - Potential for leptospirosis among urban dwellers [letter] LA - Eng MH - Animal MH - Case Report MH - Female MH - Human MH - Kidney/microbiology MH - Leptospirosis/*transmission MH - Probability MH - Specimen Handling/standards MH - *Urban Health MH - Victoria MH - Zoonoses/*transmission PT - LETTER DA - 900112 DP - 1989 Oct 16 IS - 0025-729X TA - Med J Aust PG - 484 SB - M SB - X CY - AUSTRALIA IP - 8 VI - 151 JC - M26 EM - 9003 PMID- 2593961 CU - 91 SO - Med J Aust 1989 Oct 16;151(8):484 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 90044194 AU - Lahaije JJ AU - Lustermans WB AU - Gravekamp C AU - Groen J AU - Osterhaus AD TI - [Another case of Hantaan virus infection in The Netherlands] LA - Dut MH - Adult MH - Antibodies, Viral/analysis MH - Case Report MH - English Abstract MH - Hantavirus/immunology MH - Hemorrhagic Fever with Renal Syndrome/*diagnosis/immunology MH - Human MH - Male RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 891201 DP - 1989 Oct 7 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 1990-2 CY - NETHERLANDS IP - 40 VI - 133 JC - NUK AA - Author EM - 9002 AB - In a serological survey among Dutch patients suspected of leptospirosis, using a recently developed enzyme-linked immunosorbent assay, a patient was traced with a high antibody titre to Hantaan virus. No anti-leptospira antibodies were detected in this 27-year-old man. Shortly before he had been admitted to the hospital with progressive dyspnoea and coughing, accompanied with high fever. An interstitial pneumonia was diagnosed. He subsequently developed a progressive renal failure with proteinuria and polyuria. Later a liver failure accompanied with thrombocytopenia, anaemia and coagulation disturbances occurred. Before an aetiological diagnosis was made, the patient was treated with erythromycin. The patient eventually recovered completely. Based on the clinical symptoms and the positive serology, it was concluded that the disease diagnosed had probably been caused by a Hantaan virus infection. The diagnostic value of Hantaan virus serology in patients with similar symptoms is stressed. PMID- 2572978 CU - 94 TT - Wederom een geval van Hantavirusinfectie in Nederland. EA - A SO - Ned Tijdschr Geneeskd 1989 Oct 7;133(40):1990-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 90056139 AU - Chappel RJ AU - Millar BD AU - Adler B AU - Hill J AU - Jeffers MJ AU - Jones RT AU - McCaughan CJ AU - Mead LJ AU - Skilbeck NW TI - Leptospira interrogans serovar hardjo is not a major cause of bovine abortion in Victoria. LA - Eng MH - Abortion, Veterinary/immunology/*microbiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/immunology/*microbiology MH - Female MH - Fetal Diseases/immunology/*microbiology MH - Genotype MH - Leptospira interrogans/*genetics/immunology MH - Leptospirosis/*veterinary MH - Pregnancy MH - Support, Non-U.S. Gov't MH - Victoria RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 891219 DP - 1989 Oct IS - 0005-0423 TA - Aust Vet J PG - 330-3 SB - M CY - AUSTRALIA IP - 10 VI - 66 JC - 9IE AA - Author EM - 9002 AB - The aim of this study was to determine whether evidence could be obtained of foetal infection with Leptospira interrogans serovar hardjo in aborted foetuses collected from dairy farms. Material from 197 abortions occurring over a wide area of Victoria was collected over 3 years. None of 195 foetal kidney cultures or 7 cultures from membranes was positive for leptospiral organisms. Immunogold silver staining for leptospires was performed on sections of kidneys, lungs or heart from 156 foetuses, with negative results. Evidence of transient leptospiral infection in 11 of 123 foetuses was obtained by foetal heart blood serology. Two isolates of L. interrogans serovar hardjo were obtained from the urine of milking cows. These strains were examined by restriction endonuclease analysis and both were shown to be of the genotype Hardjobovis, as have been all Australian isolates studied so far. It appears that foetal infection with serovar hardjo is not associated with any substantial proportion of bovine abortions in Victoria, in contrast to the situation in Northern Ireland. The apparent absence from Victoria of the pathogenic genotype Hardjoprajitno is a possible explanation. AD - Department of Agriculture and Rural Affairs, Veterinary Research Institute Attwood and Parkville, Victoria. PMID- 2818362 CU - 91 SO - Aust Vet J 1989 Oct;66(10):330-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 90029220 AU - Levine DF TI - Leptospirosis in the milking parlour [letter; comment] LA - Eng MH - Agricultural Workers' Diseases/*etiology MH - *Dairying MH - Human MH - Leptospirosis/*etiology PT - COMMENT PT - LETTER DA - 891212 DP - 1989 Oct IS - 0007-1064 TA - Br J Hosp Med PG - 340 SB - M CY - ENGLAND IP - 4 VI - 42 JC - BZ5 EM - 9002 CM - Comment on: Br J Hosp Med 1989 Jun;41(6):519 RO - M:LC1 PMID- 2804509 LR - 900305 CU - 91 SO - Br J Hosp Med 1989 Oct;42(4):340 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 90062452 AU - Raoult D AU - Hechemy KE AU - Baranton G TI - Cross-reaction with Borrelia burgdorferi antigen of sera from patients with human immunodeficiency virus infection, syphilis, and leptospirosis. LA - Eng MH - Acquired Immunodeficiency Syndrome/immunology MH - *Antigens, Bacterial MH - Borrelia/*immunology MH - Cross Reactions MH - Diagnostic Errors MH - Fluorescent Antibody Technique MH - Human MH - Leptospirosis/immunology MH - Lyme Disease/*diagnosis/immunology MH - Serodiagnosis MH - Syphilis/immunology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 900109 DP - 1989 Oct IS - 0095-1137 TA - J Clin Microbiol PG - 2152-5 SB - M CY - UNITED STATES IP - 10 VI - 27 JC - HSH AA - Author EM - 9003 AB - We have studied the cross-reaction with Borrelia burgdorferi of sera positive for leptospirosis, syphilis, or human immunodeficiency virus by using the microimmunofluorescence test (micro-IF). The percentage of sera reactive in the micro-IF before absorption varied from 7 to 37% and was reduced to 3 to 8% after absorption with a commercial Reiter treponemal antigen. The cross-reaction of sera positive for syphilis or human immunodeficiency virus was distinguished from the homologous reaction with sera from patients with Lyme disease in the immunoblot test results. However, the cross-reaction could not always be distinguished from the homologous reaction with sera from patients with leptospirosis whose sera scored positive in the micro-IF for B. burgdorferi. AD - Centre National de Reference des Rickettsioses, Centre Hospitalier Universitaire la Timone, Marseille, France. PMID- 2685016 CU - 91 SO - J Clin Microbiol 1989 Oct;27(10):2152-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 90019672 AU - Sperber SJ AU - Schleupner CJ TI - Leptospirosis: a forgotten cause of aseptic meningitis and multisystem febrile illness. LA - Eng MH - Adult MH - Animal MH - Case Report MH - Diagnosis, Differential MH - Dogs MH - Fever/drug therapy/*etiology MH - Human MH - Leptospira/isolation & purification MH - *Leptospirosis MH - Male MH - Meningitis/*etiology MH - Meningitis, Aseptic/diagnosis/drug therapy/*etiology MH - Penicillin G/therapeutic use MH - Prognosis MH - Weil's Disease/*complications/diagnosis/drug therapy MH - Zoonoses RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 891117 DP - 1989 Oct IS - 0038-4348 TA - South Med J PG - 1285-8 SB - A SB - M SB - X CY - UNITED STATES IP - 10 VI - 82 JC - UVH AA - Author EM - 9001 AB - Leptospirosis is a worldwide spirochetal zoonosis that spans a clinical spectrum from a mild febrile illness to a severe icteric disease with renal failure (Weil's syndrome). The illness is characteristically biphasic with conjunctival suffusion and an "immune" meningitis during the later phase of illness. Most patients, even those with severe disease, recover without residual organ impairment. The diagnosis is confirmed by serology, by culture of blood or spinal fluid during the first phase of illness, or by culture of urine during the second phase. Doxycycline is the recommended therapy and is effective if given within the first several days of illness; it may also have a role in prophylaxis. AD - Department of Medicine, University of Virginia School of Medicine, Salem. RF - 24 PMID- 2678503 CU - 90 SO - South Med J 1989 Oct;82(10):1285-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 90010281 AU - Raoult D AU - Bres P AU - Baranton G TI - Serologic diagnosis of leptospirosis: comparison of line blot and immunofluorescence techniques with the genus-specific microscopic agglutination test [letter] LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis RN - 0 (Antibodies, Bacterial) PT - LETTER DA - 891028 DP - 1989 Oct IS - 0022-1899 TA - J Infect Dis PG - 734-5 SB - A SB - M CY - UNITED STATES IP - 4 VI - 160 JC - IH3 EM - 9001 PMID- 2677165 CU - 91 SO - J Infect Dis 1989 Oct;160(4):734-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 90221142 AU - Tulli G AU - Gabini R AU - Feri M AU - Maurizi P AU - Nannoni S AU - Vignali G TI - [Multiple organ failure syndrome in infection caused by ictero- hemorragic Leptospira. Description of a clinical case] LA - Ita MH - Case Report MH - English Abstract MH - Human MH - Kidney Failure, Acute/etiology MH - Leptospira interrogans MH - Male MH - Middle Age MH - Multiple Organ Failure/*etiology MH - Respiratory Distress Syndrome, Adult/etiology MH - Syndrome MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 900521 DP - 1989 Oct IS - 0375-9393 TA - Minerva Anestesiol PG - 423-6 CY - ITALY IP - 10 VI - 55 JC - N26 AA - Author EM - 9007 AB - A 53 years old fisherman was admitted to General Intensive Care Unit in Arezzo with signs and symptoms of Weil disease. An early acute respiratory failure developed. Radiological and haemodynamic findings confirmed a diagnosis of ARDS. The patient developed a severe jaundice, acute renal failure and ARDS (MOF multiple organs failure). To support different failures of the organs, CMV (continuous mandatory ventilation: CPPV with PEEP max 10 cm H2; IRV max 2:1) and AMV (assisted mandatory ventilation: Pressure Support Ventilation), haemofiltration, haemoperfusion and plasmapheresis were simultaneously used, that got better and better renal and respiratory performances. Haemodynamic worsening by PEEP during extracorporeal treatment was overcome by PSV very useful new ventilatory procedure even during weaning period. The patient treated in such manner survived without important disabilities. This care confirms that ARDS (non cardiogenic edema) and MOF can develop during Icterohaemorrhagic Leptospirosis. PMID- 2633075 CU - 90 TT - MOFS (multiple organs failure syndrome) in corso di infezione da Leptospira ittero-emorragica. Descrizione di un caso clinico. EA - A SO - Minerva Anestesiol 1989 Oct;55(10):423-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 90217996 AU - Vinh TU AU - Shi MH AU - Adler B AU - Faine S TI - Characterization and taxonomic significance of lipopolysaccharides of Leptospira interrogans serovar hardjo. LA - Eng MH - Carbohydrates/analysis MH - Comparative Study MH - Electrophoresis, Polyacrylamide Gel MH - Fatty Acids/analysis MH - Immunohistochemistry MH - Leptospira interrogans/*analysis/classification MH - Lipopolysaccharides/*isolation & purification MH - Phenols MH - Sodium Dodecyl Sulfate MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Fatty Acids) RN - 0 (Lipopolysaccharides) RN - 0 (Phenols) RN - 108-95-2 (phenol) RN - 151-21-3 (Sodium Dodecyl Sulfate) PT - JOURNAL ARTICLE DA - 900511 DP - 1989 Oct IS - 0022-1287 TA - J Gen Microbiol PG - 2663-73 SB - M CY - ENGLAND VI - 135 ( Pt 10) JC - I87 AA - Author EM - 9007 AB - Lipopolysaccharides (LPSs) from Leptospira interrogans serovar hardjo (reference strain hardjoprajitno and strain hardjobovis) were prepared by the hot phenol-water procedure. High yields of LPSs were found in the phenol phase. Gel electrophoresis of the phenol phase LPSs showed similar patterns for all strains in contrast to the different patterns found in the water phase LPSs. Sugar composition was also similar among all strains with rhamnose as the predominant sugar. Mannosamine was detected by high performance thin layer and gas-liquid chromatography. 2-Keto-3-deoxyoctonic acid (KDO) was comparable with authentic KDO by paper chromatography. Periodate oxidation at near neutral pH with or without prior hydrolysis showed that most of the KDO was substituted. The fatty acid composition of strain hardjobovis LPS was slightly different from that of the reference strain hardjoprajitno. Myristic and 3-hydroxymyristic acid were not detected in any of the LPS preparations. In conjunction with genetic and other data, the two strains are sufficiently different to be regarded as members of two separate species sharing common antigens. There is sufficient evidence to rename the hardjoprajitno strain type L. interrogans hardjo-p, and the hardjobovis strain type L. borgpeterseni hardjo-b. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 2632669 CU - 92 SO - J Gen Microbiol 1989 Oct;135 ( Pt 10):2663-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 90070642 AU - Zhou WJ AU - Nie DK AU - Wu SH TI - [Studies on enhancement of nonspecific resistance to infection by leptospiral lipopolysaccharide. II. The mechanisms of the nonspecific protective activity of the LPS] LA - Chi MH - Acid Phosphatase/metabolism MH - Animal MH - English Abstract MH - Female MH - Guinea Pigs MH - *Leptospira MH - Lipopolysaccharides/*pharmacology MH - Macrophages/drug effects MH - Mice MH - Mice, Inbred C57BL MH - Phagocytosis/*drug effects RN - EC 3.1.3.2 (Acid Phosphatase) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 900108 DP - 1989 Oct IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 383-9 CY - CHINA IP - 5 VI - 29 JC - XNA AA - Author EM - 9003 AB - Leptospiral lipopolysaccharide can enhance the nonspecific resistance of host to infection. By researching its mechanism, we found: (1) The phagocytic function of peritoneal macrophages of guinea pigs was strengthened by E-LPS and L-LPS; (2) L-LPS and E-LPS activated peritoneal macrophages of mice then enlarging the cell raji, and increase the quantity and activity of intracellular acid phosphatase. Relatively, the L-LPS might have a greater action in synthesis of the enzyme, while the E-LPS mainly enhanced the activity of the enzyme; (3) L-LPS and E-LPS appeared to be immunomodulant. When they were injected 3d after immunizing the mice with SRBC, immune adjuvant effect developed; however, if the injection of LPS was made 24h prior to the immunization, it would result in immunosuppression. PMID- 2588563 CU - 91 EA - A SO - Wei Sheng Wu Hsueh Pao 1989 Oct;29(5):383-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 90062475 AU - Van Eys GJ AU - Gravekamp C AU - Gerritsen MJ AU - Quint W AU - Cornelissen MT AU - Schegget JT AU - Terpstra WJ TI - Detection of leptospires in urine by polymerase chain reaction. LA - Eng MH - Animal MH - Base Sequence MH - Cattle MH - Cattle Diseases/*diagnosis/microbiology/urine MH - Comparative Study MH - DNA, Bacterial/genetics MH - Evaluation Studies MH - Leptospira/genetics/*isolation & purification MH - Leptospirosis/diagnosis/urine/*veterinary MH - Molecular Sequence Data MH - Polymerase Chain Reaction MH - Support, Non-U.S. Gov't RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 900109 DP - 1989 Oct IS - 0095-1137 TA - J Clin Microbiol PG - 2258-62 SB - M CY - UNITED STATES IP - 10 VI - 27 JC - HSH AA - Author EM - 9003 AB - Primers for polymerase chain reaction (PCR) were synthesized from clones derived from a Leptospira hardjo (type hardjobovis) library. One pair of synthetic oligonucleotide primers was selected for further analysis. Under experimental conditions an amplification was obtained with DNA of Leptospira interrogans of some serovars belonging to serogroup sejroe. However, very little or no amplification was observed with DNA from other serovars of this group. No amplification was observed with DNA from other serogroups, other bacteria, or eucaryotic organisms. Cattle urine, seeded with hardjobovis, was processed in several ways and subsequently subjected to PCR. Boiling of the samples or treatment with detergents appeared to be most effective. Urine samples containing fewer than 10 leptospires gave a positive result in the PCR assay. Twenty urine samples obtained from a slaughterhouse or farm cows were investigated using the PCR assay, culture isolation, dot and quick blot hybridization, and serological tests. This comparative study suggests that amplification by PCR may be a valuable method for the detection of leptospires in cattle urine. AD - N. H. Swellengrebel Laboratory for Tropical Hygiene, Royal Tropical Institute, Amsterdam, The Netherlands. RO - M:CNR PMID- 2584377 LR - 900323 CU - 91 SO - J Clin Microbiol 1989 Oct;27(10):2258-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 90048194 AU - Margulis MS AU - Erukhimov EA AU - Andreiman LA AU - Viksna LM TI - Temporary organ substitution by hemoperfusion through suspension of active donor hepatocytes in a total complex of intensive therapy in patients with acute hepatic insufficiency. LA - Eng MH - Adult MH - Aged MH - Aged, 80 and over MH - Critical Care/*methods MH - Electroencephalography MH - Hemoperfusion/*methods MH - Hepatic Encephalopathy/*therapy MH - Human MH - Liver/*cytology MH - Middle Age PT - JOURNAL ARTICLE DA - 891208 DP - 1989 Oct IS - 0300-9572 TA - Resuscitation PG - 85-94 SB - M CY - IRELAND IP - 1 VI - 18 JC - R8Q AA - Author EM - 9002 AB - The results of intensive therapy and temporary organ substitution by hemoperfusion through a suspension of active hepatocytes in 126 patients suffering from acute hepatic insufficiency (AHI) induced by virus B hepatitis, virus non-A, non-B hepatitis, acute toxic hepatitis, active liver cirrhosis, sepsis leptospirosis long-term subhepatic jaundice are presented in this paper. Hepatic encephalopathia confirmed both clinically and electroencephalographically was registered in all the patients. The patients were subdivided into two groups: a complex of commonly used curative measures according to the intensive therapy for AHI was applied in Group A (67 patients); in Group B (59 patients), alongside with the above measures, temporary organ substitution by hemoperfusion through a suspension of active porky hepatocytes was also performed. The lethality in Group A made up 59% and that in Group B was 37%. AD - Department of Experimental Surgery and Temporary Organ Substitution, Riga Medical Institute, Latvia, USSR. PMID- 2554450 CU - 93 SO - Resuscitation 1989 Oct;18(1):85-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 90070643 AU - Wu SH AU - Jiang SX AU - Wang HQ AU - Nie DK AU - Zhu GF TI - [Studies on endotoxin of Leptospira. V. The effect of EDTA-Na on the release of the LPS of Leptospira interrogans serovar lai] LA - Chi MH - Edetic Acid/*pharmacology MH - English Abstract MH - Leptospira interrogans/drug effects/*metabolism MH - Lipopolysaccharides/*secretion RN - 0 (Lipopolysaccharides) RN - 60-00-4 (Edetic Acid) PT - JOURNAL ARTICLE DA - 900108 DP - 1989 Oct IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 390-3 CY - CHINA IP - 5 VI - 29 JC - XNA AA - Author EM - 9003 AB - The yield of leptospiral LPS was able to increase 1-2 times when the cells were treated with EDTA-Na before extracting with hot phenal-water method. The colours and solubility of L-LPS were improved. When the leptospiral cells were stored for a long period of time, and treated by EDTA-Na, the phase distribution of the LPS changed, i.e. they returned from water phase into phenol phase. Such change was related to the quantity of both the saccharide and lipid. PMID- 2511666 CU - 91 EA - A SO - Wei Sheng Wu Hsueh Pao 1989 Oct;29(5):390-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 91191010 AU - Hodgin EC AU - Miller DA AU - Lozano F TI - Leptospira abortion in horses. LA - Eng MH - Abortion, Veterinary/microbiology/*pathology MH - Animal MH - Animals, Newborn MH - Case Report MH - Female MH - Fetal Death/microbiology/pathology/*veterinary MH - Fetus/pathology MH - Horse Diseases/microbiology/*pathology MH - Horses MH - Leptospirosis/microbiology/pathology/*veterinary MH - Male MH - Pregnancy PT - JOURNAL ARTICLE DA - 910510 DP - 1989 Oct IS - 1040-6387 TA - J Vet Diagn Invest PG - 283-7 SB - M CY - UNITED STATES IP - 4 VI - 1 JC - A2D AA - Author EM - 9107 AB - Leptospira infection was diagnosed as the cause of 4 late-term equine abortions/stillbirths and 1 neonatal death in Louisiana. The most consistent gross and microscopic lesions were icterus and interstitial nephritis, respectively. Diagnoses were based on visualization of compatible spirochetes in Warthin-Starry-stained sections of kidney, liver, and placenta. Confirmation by immunofluorescence was made in 2 cases. AD - Louisiana Veterinary Medical Diagnostic Laboratory, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803. PMID- 2488711 SO - J Vet Diagn Invest 1989 Oct;1(4):283-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 90015409 AU - Huitema SW AU - Pal TM AU - Groothoff JW TI - [Milker's fever, an occupational disease on the increase] LA - Dut MH - Agglutination Tests MH - Agricultural Workers' Diseases/*immunology MH - Antibodies, Bacterial/analysis MH - *Dairying MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Leptospira interrogans/*immunology MH - Leptospirosis/*immunology/microbiology/transmission RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 891113 DP - 1989 Sep 30 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 1939-41 CY - NETHERLANDS IP - 39 VI - 133 JC - NUK AA - Author EM - 9001 AB - In order to obtain a better picture of the course of dairy farm fever, a leptospirosis caused by hardjo, an inquiry by means of questionnaires was conducted into its symptomatology and its trade-connected risk factors. The inquiry was performed in 32 seropositive dairy farmers and a matched-pair control group. All persons involved were living or working on contaminated farms. Of the seropositive persons 63% reported symptoms suggestive of dairy farm fever and in all of them there had been obvious fatigue of an extreme and protracted nature and an often lengthy period of recovery. The results of this investigation suggest underreporting of this disease. Besides vaccination and/or treatment of the dairy cattle adjustment of operations on dairy farms (e.g. wearing personal protection) might be feasible for prevention. The causal relationship between occupation and dairy farm fever indicates an occupational disease. PMID- 2797315 CU - 91 TT - Melkerskoorts, een beroepsziekte in opmars. EA - A SO - Ned Tijdschr Geneeskd 1989 Sep 30;133(39):1939-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 90021002 AU - Ellis WA AU - Montgomery JM AU - McParland PJ TI - An experimental study with a Leptospira interrogans serovar bratislava vaccine. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - *Bacterial Vaccines MH - Kidney Diseases/prevention & control/*veterinary MH - Leptospira interrogans/*immunology MH - Swine MH - Swine Diseases/blood/*prevention & control MH - Vaccination/veterinary MH - Weil's Disease/blood/prevention & control/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 891120 DP - 1989 Sep 16 IS - 0042-4900 TA - Vet Rec PG - 319-21 SB - M CY - ENGLAND IP - 12 VI - 125 JC - XBS AA - Author EM - 9001 AB - The intramuscular vaccination of pigs with two doses, two weeks apart, of a Leptospira interrogans serovar bratislava bacterin, protected pigs against renal infection when challenged with bratislava strains six weeks later but did not protect pigs challenged after 26 weeks. AD - Veterinary Research Laboratories, Stormont, Belfast. PMID- 2800262 CU - 91 SO - Vet Rec 1989 Sep 16;125(12):319-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 90038602 AU - Yaqoob M AU - Ahmad R TI - Mononeuritis multiplex as an unusual complication of leptospirosis [letter] LA - Eng MH - Accidents, Traffic MH - Case Report MH - Human MH - Male MH - Middle Age MH - Neuritis/*etiology MH - Weil's Disease/*complications PT - LETTER DA - 891215 DP - 1989 Sep IS - 0163-4453 TA - J Infect PG - 188-9 SB - M CY - ENGLAND IP - 2 VI - 19 JC - IG9 EM - 9002 PMID- 2809239 CU - 91 SO - J Infect 1989 Sep;19(2):188-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 90024043 AU - Park SK AU - Lee SH AU - Rhee YK AU - Kang SK AU - Kim KJ AU - Kim MC AU - Kim KW AU - Chang WH TI - Leptospirosis in Chonbuk Province of Korea in 1987: a study of 93 patients. LA - Eng MH - Agglutination Tests MH - Anemia/etiology MH - *Disease Outbreaks MH - Hematocrit MH - Hemoptysis/etiology MH - Human MH - Kidney/pathology MH - Korea/epidemiology MH - Leptospirosis/blood/complications/*epidemiology/pathology MH - Liver/pathology MH - Lung/pathology MH - Muscles/pathology MH - Myocardium/pathology MH - Platelet Count MH - Weil's Disease/blood/complications/*epidemiology/pathology PT - JOURNAL ARTICLE DA - 891102 DP - 1989 Sep IS - 0002-9637 TA - Am J Trop Med Hyg PG - 345-51 SB - A SB - M CY - UNITED STATES IP - 3 VI - 41 JC - 3ZQ AA - Author EM - 9001 AB - Leptospirosis is a zoonosis with protean clinical manifestation. Diagnosis requires a high index of suspicion and is confirmed by isolation of the organism or, more commonly, by serologic studies. In the fall of 1987, after severe flooding, we saw 93 patients with leptospirosis, confirmed by a microagglutination test. Thirteen percent of the patients had no clinical or laboratory findings except fever and headache, but the rest had mild to severe manifestations. Jaundice, renal failure, and aseptic meningitis were not common, but pulmonary symptoms, when present, were striking. The mortality rate was 5%. The main cause of death was asphyxiation due to massive hemoptysis from pulmonary hemorrhage and acute respiratory failure. AD - Chonbuk National University Medical School, Korea. PMID- 2802020 SO - Am J Trop Med Hyg 1989 Sep;41(3):345-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 90002136 AU - Arimitsu Y AU - Fukumura K AU - Shingaki Y TI - Distribution of leptospirosis among stray dogs in the Okinawa Islands, Japan: comparison of the microcapsule and microscopic agglutination tests. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Dog Diseases/*epidemiology MH - Dogs MH - Female MH - Japan/epidemiology MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Male RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 891107 DP - 1989 Sep-Oct IS - 0007-1935 TA - Br Vet J PG - 473-7 CY - ENGLAND IP - 5 VI - 145 JC - B5C AA - Author EM - 9001 AB - Three hundred and thirty-eight sera collected from stray dogs in the Okinawa islands were examined for antibodies against Leptospira interrogans using the microscopic agglutination test (MAT) and the one- point microcapsule agglutination test (MCAT). Seventy-eight sera (23%) showed a positive reaction to at least one of the six serovar antigens, and 69 of these reacted with serovar canicola by microcapsule agglutination test. The mixed microcapsule agglutination test detected 68 of the microscopic agglutination test-positive sera, and the 10 remaining were negative by microcapsule agglutination test. On the other hand, a single microcapsule agglutination test which was sensitized with serovar canicola detected 77 of the microscopic agglutination test-positive sera and the remaining one was microcapsule agglutination test-negative. PMID- 2790440 CU - 91 SO - Br Vet J 1989 Sep-Oct;145(5):473-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 90161558 AU - Grimont F AU - Chevrier D AU - Grimont PA AU - Lefevre M AU - Guesdon JL TI - Acetylaminofluorene-labelled ribosomal RNA for use in molecular epidemiology and taxonomy. LA - Eng MH - Bacteria/*classification/genetics MH - Enzyme-Linked Immunosorbent Assay MH - Escherichia coli MH - Nucleotide Mapping MH - Restriction Mapping MH - *RNA Probes MH - *RNA, Ribosomal MH - Support, Non-U.S. Gov't MH - 2-Acetylaminofluorene/*diagnostic use RN - 0 (RNA Probes) RN - 0 (RNA, Ribosomal) RN - 53-96-3 (2-Acetylaminofluorene) PT - JOURNAL ARTICLE DA - 900326 DP - 1989 Sep IS - 0923-2508 TA - Res Microbiol PG - 447-54 SB - M CY - FRANCE IP - 7 VI - 140 JC - R6F AA - Author EM - 9005 AB - The use of acetylaminofluorene-labelled 16 + 23S rRNA (from Escherichia coli) is described for determining rRNA-gene-restriction patterns. The labelled probe allowed molecular fingerprinting of bacteria belonging to diverse phylogenetic branches (Enterobacteriaceae, Haemophilus, Pseudomonas, Acinetobacter, Brucella, Leptospira, Cytophaga, Campylobacter, Methylophaga). The labelled probe can be stored frozen (- 20 degrees C) for at least a year and can endure vacuum dessication, ethanol precipitation or lyophilization. AD - Unite 199 INSERM, Institut Pasteur, Paris. PMID- 2696056 CU - 92 SO - Res Microbiol 1989 Sep;140(7):447-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 90048525 AU - Johnson RC TI - Isolation techniques for spirochetes and their sensitivity to antibiotics in vitro and in vivo. LA - Eng MH - Animal MH - Antibiotics/*pharmacology/therapeutic use MH - Borrelia/drug effects/isolation & purification MH - Borrelia burgdorferi/drug effects/isolation & purification MH - Borrelia Infections/drug therapy MH - Human MH - Leptospira/drug effects/isolation & purification MH - Leptospirosis/drug therapy MH - Spirochaetales/*drug effects/isolation & purification MH - Spirochaetales Infections/*drug therapy MH - Syphilis/drug therapy MH - Treponema pallidum/drug effects/isolation & purification RN - 0 (Antibiotics) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 891220 DP - 1989 Sep-Oct IS - 0162-0886 TA - Rev Infect Dis PG - S1505-10 SB - M CY - UNITED STATES VI - 11 Suppl 6 JC - SXN AA - Author EM - 9002 AB - Leptospira interrogans can be cultured from blood and cerebrospinal fluid during the first week of leptospirosis and from urine thereafter. Studies of in vitro sensitivity indicate that these organisms are sensitive to most antibiotics. Tetracycline and penicillin G are most often used clinically, although laboratory studies suggest that the bactericidal activity of penicillin G may be inadequate. Treponema pallidum cannot be satisfactorily cultured. It is identified by dark- field microscopy. Studies of in vivo sensitivity show that penicillin G is highly active against the syphilis pathogen. Since syphilis and gonorrhea may occur simultaneously, ceftriaxone, which is as active as penicillin G against T. pallidum but is also active against penicillinase-producing gonococci, is a logical choice for therapy. Borrelia burgdorferi has been cultured from the blood, cerebrospinal fluid, and skin of patients with Lyme disease. In vitro studies have shown tetracycline and erythromycin to be effective against B. burgdorferi and penicillin G to be less so, although all are commonly used clinically. Ceftriaxone has also proven to be highly effective in laboratory studies and for clinical treatment. AD - Department of Microbiology, University of Minnesota Medical School, Minneapolis. RF - 35 PMID- 2682963 CU - 91 SO - Rev Infect Dis 1989 Sep-Oct;11 Suppl 6:S1505-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 90048518 AU - Schmid GP TI - Epidemiology and clinical similarities of human spirochetal diseases. LA - Eng MH - Animal MH - Borrelia Infections/epidemiology/etiology/*transmission MH - Human MH - Leptospirosis/epidemiology/etiology/*transmission MH - Spirochaetales Infections/epidemiology/etiology/*transmission MH - Treponemal Infections/epidemiology/etiology/*transmission MH - Zoonoses PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, ACADEMIC DA - 891220 DP - 1989 Sep-Oct IS - 0162-0886 TA - Rev Infect Dis PG - S1460-9 SB - M CY - UNITED STATES VI - 11 Suppl 6 JC - SXN AA - Author EM - 9002 AB - Lyme disease, first identified in 1975, is the most recently recognized of the seven human spirochetal diseases; the evolving clinical picture of Lyme disease indicates it shares many features with the other diseases. These similarities are striking in view of the diverse epidemiology of the seven diseases, which are caused by Treponema species (spread by human-to-human contact) or Leptospira or Borrelia species (zoonoses). These similarities include the following: (1) skin or mucous membrane as portal of entry; (2) spirochetemia early in the course of disease, with wide dissemination through tissue and body fluid; and (3) one or more subsequent stages of disease, often with intervening latent periods. Lyme disease shares with many spirochetal diseases a tropism for skin and neurologic and cardiovascular manifestations, whereas chronic arthritis is unique to Lyme disease. These similarities and dissimilarities offer opportunities to discover which properties unique to the pathogenic spirochetes are responsible for clinical manifestations and suggest that certain clinical features of patients with spirochetal diseases other than Lyme disease may someday be recognized in patients with Lyme disease. AD - Division of Sexually Transmitted Diseases, Centers for Disease Control, Atlanta, Georgia 30333. RF - 41 PMID- 2682958 CU - 90 SO - Rev Infect Dis 1989 Sep-Oct;11 Suppl 6:S1460-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 90169920 AU - Xiao JG AU - Dai BM TI - [The ultrastructure of leptospires after freeze-etching] LA - Chi MH - Animal MH - English Abstract MH - Freeze Etching MH - Leptospira/*ultrastructure MH - Leptospira interrogans/ultrastructure MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 900406 DP - 1989 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 262-5 CY - CHINA IP - 3 VI - 20 JC - GEB AA - Author EM - 9006 AB - The ultrastructure of three strains of leptospires, i.e. L. interrogans serovar Lai strain 017, L. biflexa serovar patoc strain Patoc I and L. illini strain 3055, were studied with the technique of freeze-etching replica. The results showed that (1) the ultrastructure of leptospires after freeze-etching are similar to that observed by means of negative staining and ultrasectioning. There are no dramatic differences among strains of leptospires studied. (2) Globular particles exposed on the resulting two inner membrane faces are asymmetrically distributed. Large areas on EF face studied with numerous globular particles, whereas the PF face had few of them. The density of globular particles varies in different parts of leptospires, from 776/microns2 to 2303/microns2. The globular particles, 14.25 +/- 2.25 nm in diameter, represent membrane proteins in outer envelope of leptospires. (3) Axial filament, 20 nm in diameter, were seen closely surrounded by a 7 nm sheath-like structure. (4) There are subcellular structures in cytoplasm of leptospires. They appear to be ribosomes, chromatins and inclusions. PMID- 2625330 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1989 Sep;20(3):262-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 90169919 AU - Qing GF AU - Dai BM TI - [Production, identification of four McAbs against leptospiral outer membrane antigens, and analyses of outer membrane antigens of leptospires with McAbs] LA - Chi MH - Animal MH - Antibodies, Monoclonal/*analysis/biosynthesis MH - Antigens, Bacterial/*analysis MH - Bacterial Outer Membrane Proteins/*immunology MH - Blotting, Western MH - Electrophoresis, Polyacrylamide Gel/methods MH - English Abstract MH - Leptospira interrogans/*immunology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) PT - JOURNAL ARTICLE DA - 900406 DP - 1989 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 257-61 CY - CHINA IP - 3 VI - 20 JC - GEB AA - Author EM - 9006 AB - Four McAbs (1A7E7, 2F9D4, 2G3H5, 1A7H12) against outer membrane antigens of L. interrogans serovar Lai strain 017 were produced by hybridoma technique. McAb 1A7E7 was identified to be IgG2a, the rest IgG1 by immunodiffusion. Outer membrane antigens of three pathogenic leptospiral strains (017, 601, 156) and two non-pathogenic leptospiral strains (Patoc I, 3055) were analysed by SDS- polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting with McAbs. It was found that McAb 1A7E7 recognized specifically the 42kd antigenic band of strain 017; McAb 2F9D4 the 42kd antigenic bands of strain 017, 601, 156, and McAbs 2G3H5 and 1A7H12 the 31 kd antigenic bands of 017, 601, 156. Further study of antigenic properties possessed by pathogenic leptospira may provide some new clues to look for specific diagnostic and protective antigens. PMID- 2625329 CU - 91 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1989 Sep;20(3):257-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 90139440 AU - Turner JS AU - Willcox PA TI - Respiratory failure in leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Case Report MH - Hemoptysis/*etiology/radiography MH - Human MH - Leptospirosis/*complications/radiography MH - Lung/radiography MH - Male MH - Respiratory Insufficiency/*etiology PT - JOURNAL ARTICLE DA - 900313 DP - 1989 Sep IS - 0033-5622 TA - Q J Med PG - 841-7 SB - M CY - ENGLAND IP - 269 VI - 72 JC - QKZ AA - Author EM - 9005 AB - We report on four cases of leptospirosis with pulmonary manifestations as their presenting features. With adequate supportive therapy the prognosis is good. Leptospirosis should be considered in the differential diagnosis of pulmonary haemorrhage. AD - Respiratory Clinic, Groote Schuur Hospital, South Africa. PMID- 2616729 SO - Q J Med 1989 Sep;72(269):841-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 90091224 AU - Matsumuro K AU - Izumo S AU - Nakamura A AU - Moritoyo T AU - Osame M TI - [Two cases of facial diplegia with elevated serum antibodies to Borrelia burgdorferi] LA - Jpn MH - Antibodies, Bacterial/*analysis MH - Borrelia burgdorferi/*immunology MH - Case Report MH - English Abstract MH - Facial Paralysis/etiology/*immunology MH - Human MH - Lyme Disease/complications/immunology MH - Male MH - Middle Age MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900208 DP - 1989 Sep IS - 0009-918X TA - Rinsho Shinkeigaku PG - 1152-5 CY - JAPAN IP - 9 VI - 29 JC - DF2 AA - Author EM - 9004 AB - Lyme disease, a tick-borne infection with spirochete named Borrelia burgdorferi, is a complex multi-organ disorder involving neurological complication. Recently, the existence of Lyme disease was also recognized in middle Japan. We described here two cases of facial diplegia with elevated serum antibodies to B. burgdorferi. Case 1 was a 48 year-old man, who developed facial diplegia on April 29, 1987, and referred to our hospital on May 1. Neurological examination showed facial diplegia in addition to right-sided hemiparesis due to head injury of twenty years ago. The cell count of the cerebrospinal fluid was 17/mm3 and the protein was 139.9 mg/dl. The serological examinations for B. burgdorferi were performed by means of immunoperoxidase test. This patient had no serum IgG antibodies to B. burgdorferi on admission. However, twelve weeks later his serum showed significant elevation of IgG antibodies (titer: X400). Tests for syphilis and leptospira were negative. Based on these observation, we considered that facial diplegia of this patient was associated with the infection of B. burgdorferi. His facial diplegia remained unchanged with oral corticosteroid treatment. Case 2 was a 64 year-old man, who developed facial diplegia on May 31, 1987, and referred to our hospital on June 3. Neurological examinations were entirely negative except for facial diplegia. The findings of the cerebrospinal fluid showed the albumin cytologic dissociation with the cell count 2/mm3 and the protein 85.4 mg/dl. Serum IgG antibodies to B. burgdorferi were present (titer: X200) on admission. However, seven weeks later his serum showed a marked elevation of IgG antibodies (titer: X1600). Tests for syphilis were negative.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 2598542 CU - 91 EA - A SO - Rinsho Shinkeigaku 1989 Sep;29(9):1152-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 90071222 AU - Khisamov GZ AU - Volokhova NA TI - [Electrophoretic study of the outer membrane proteins of leptospirae] LA - Rus MH - Bacterial Outer Membrane Proteins/*analysis/isolation & purification MH - Comparative Study MH - Electrophoresis, Polyacrylamide Gel/methods MH - English Abstract MH - Leptospira/*analysis/classification/pathogenicity RN - 0 (Bacterial Outer Membrane Proteins) PT - JOURNAL ARTICLE DA - 900108 DP - 1989 Sep IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 26-8 SB - M CY - USSR IP - 9 JC - Y9O AA - Author EM - 9003 AB - The outer membranes of pathogenic and saprophytic leptospires have been isolated. The spectrum of outer membrane proteins in three saprophytic and one pathogenic Leptospira strains has been studied by means of electrophoresis in polyacrylamide gel. In Leptospira strains VGNKI-6 (pathogenic) and G-80 (saprophytic) identical proteins, as well as proteins similar in their Rf value, have been detected. The possibility of using strain G-80 for the development of leptospiral vaccine against serovars having common surface antigens with this strain has been suggested. PMID- 2588876 CU - 91 TT - Elektroforeticheskoe issledovanie belkov naruzhnoi obolochki leptospir. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1989 Sep;(9):26-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 91045373 AU - Droszcz W AU - Dziubek Z AU - Kajfasz P AU - Wrzosek B TI - [Acute leptospirosis after deliberate infection with rat tissues] LA - Pol MH - Acute Disease MH - Adult MH - Animal MH - Case Report MH - Human MH - Leptospirosis/*etiology/transmission/veterinary MH - Male MH - Malingering/*complications MH - Prisoners/*psychology MH - Rats MH - Rodent Diseases/*transmission PT - JOURNAL ARTICLE DA - 901219 DP - 1989 Aug 21-28 IS - 0032-3756 TA - Pol Tyg Lek PG - 803-4 CY - POLAND IP - 34-35 VI - 44 JC - PBY EM - 9102 PMID- 2485896 TT - Ostra leptospiroza w przebiegu rozmyslnego zakazenia tkankami szczura. SO - Pol Tyg Lek 1989 Aug 21-28;44(34-35):803-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 90009540 AU - Thompson JC AU - Manktelow BW TI - Pathogenesis of renal lesions in haemoglobinaemic and non- haemoglobinaemic leptospirosis. LA - Eng MH - Animal MH - Comparative Study MH - Female MH - Hamsters MH - Hemoglobins/*analysis MH - Kidney/*ultrastructure MH - Kidney Diseases/etiology/*pathology MH - Kidney Glomerulus/*ultrastructure MH - Kidney Tubules, Proximal/ultrastructure MH - Leptospira interrogans MH - Male MH - Mesocricetus MH - Microscopy, Electron MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 891113 DP - 1989 Aug IS - 0021-9975 TA - J Comp Pathol PG - 201-14 SB - M CY - ENGLAND IP - 2 VI - 101 JC - HVB AA - Author EM - 9001 AB - Hamsters were infected with Leptospira interrogans serovar ballum or Leptospira interrogans serovar pomona and the kidney lesions were compared by light and electron microscopy. Ballum and pomona both caused severe clinical signs and death within 6 days in some animals, although only ballum was associated with red blood cell destruction and haemoglobinaemic nephrosis. With ballum infections it is difficult to distinguish degenerate changes resulting from leptospiral "toxins" from those resulting from hypoxia and haemoglobinaemic nephrosis because large numbers of organisms and haemoglobinaemia coincide shortly before death. Although large numbers of leptospires were seen within the renal interstitium and blood vessels in animals dying shortly after infection, organisms were seen only in the proximal convoluted tubules of those surviving until 14 days. It is thought that leptospires are carried by the bloodstream and migrate at random throughout all body tissues. When antibody develops, only those in the renal tubules remain. The random migration results in some leptospires entering tubules at all levels of the nephron but there are good grounds for believing that the normal changes in composition of the glomerular filtrate as it passes through the nephron are increasingly deleterious to leptospiral survival. This probably explains why leptospires are found predominantly in the proximal convoluted tubules of animals after the development of specific immunity. AD - Department of Veterinary Pathology and Public Health, Massey University, Palmerston North, New Zealand. PMID- 2794156 CU - 90 SO - J Comp Pathol 1989 Aug;101(2):201-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 89378151 AU - Everard CO AU - Hayes RJ AU - Edwards CN TI - Leptospiral infection in school-children from Trinidad and Barbados. LA - Eng MH - Adolescence MH - Age Factors MH - Antibodies, Bacterial/*analysis MH - Barbados MH - Child MH - Cross-Sectional Studies MH - Female MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology MH - Longitudinal Studies MH - Male MH - Questionnaires MH - Random Allocation MH - Regression Analysis MH - Risk Factors MH - Rural Population MH - Socioeconomic Factors MH - Support, Non-U.S. Gov't MH - Trinidad and Tobago MH - Urban Population RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 891020 DP - 1989 Aug IS - 0950-2688 TA - Epidemiol Infect PG - 143-56 SB - M CY - ENGLAND IP - 1 VI - 103 JC - EPI AA - Author EM - 8912 AB - A serological survey for leptospiral agglutinins was undertaken between 1980 and 1983 in over 500 Barbadian and 500 Trinidadian school-children aged 7-14 years. The children were selected randomly from urban and rural schools, and examined three times at approximately annual intervals. A total of 12.5% of the Barbadian children and 9.5% of the Trinidadian children were seropositive at a titre of 50 using the microscopic agglutination test. On both islands, seroprevalence was higher in males than females, the difference being significant in rural schools. There was no evidence of a difference in prevalence between urban and rural schools, or between junior and secondary age-ranges. Analysis of the association of serology with socio-economic and behavioural factors showed a significant association in Trinidad with father's occupation, but most other variables on both islands showed only weak non-significant associations. Fourteen children in Trinidad and three in Barbados seroconverted. Seroconversion in Trinidad occurred at a rate of 1.6% per annum and was significantly associated with livestock contact and with absence of a tapped water supply. In Trinidad, Autumnalis was the most commonly recorded serogroup, but this accounted for less than a quarter of seropositives. In Barbados, Panama accounted for over half the seropositives and was about four times more common than the next most common serogroup, Autumnalis. In Barbados, 39 persons aged 19 or less were hospitalized with leptospirosis between November 1979 and December 1986. Average annual incidence rates were 2.2, 4.9 and 13.3 per 100,000 in the 5-9, 10-14 and 15-19 age-groups, respectively. AD - MRC/Government of Barbados Leptospirosis Project, Veterinary Diagnostic Laboratory, St Michael. PMID- 2789146 CU - 91 SO - Epidemiol Infect 1989 Aug;103(1):143-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 89391929 AU - Luyven G AU - Schonberg A TI - [The isolation and differentiation of leptospires from cattle drinking water] LA - Ger MH - Animal MH - Cattle MH - English Abstract MH - Leptospira/*isolation & purification MH - *Water Microbiology MH - *Water Supply PT - JOURNAL ARTICLE DA - 891018 DP - 1989 Aug 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 272-4 CY - GERMANY, WEST IP - 8 VI - 102 JC - 9Q8 AA - Author EM - 8912 AB - The cultural isolation and identification of leptospires from three water samples of farm wells were described. All three strains isolated belong to the apathogenic species L. biflexa. The cattle stock of these farms (A, B, C) had reacted serologically to serovars hardjo and grippotyphosa. The strain isolated from farm A is a new serovar called krefeldi and belongs to serogroup Doberdo. The strain isolated from farm B belongs to serovar montefiascone of serogroup Botanica and the strain from farm C to serovar bessemans of serogroup Bessemans. It is remarkable that serovar krefeldi with all the sera of farm A (titre up to 1:40) and only with part of the sera of farm B reacted. PMID- 2783102 TT - Beitrag zur Isolierung und Differenzierung von Leptospiren aus Viehtranken. EA - A SO - Berl Munch Tierarztl Wochenschr 1989 Aug 1;102(8):272-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 89350352 AU - Schmidt DR AU - Winn RE AU - Keefe TJ TI - Leptospirosis. Epidemiological features of a sporadic case. LA - Eng MH - Animal MH - *Animals, Domestic MH - Case Report MH - Dog Diseases/*transmission MH - Dogs MH - Human MH - Leptospira MH - Leptospira canicola MH - Leptospirosis/epidemiology/*etiology/veterinary MH - Male MH - Middle Age MH - Texas MH - Zoonoses/transmission PT - JOURNAL ARTICLE DA - 890911 DP - 1989 Aug IS - 0003-9926 TA - Arch Intern Med PG - 1878-80 SB - A SB - M SB - X CY - UNITED STATES IP - 8 VI - 149 JC - 7FS AA - Author EM - 8911 AB - Leptospirosis occurred in a 45-year-old man with presumed infection from an exposure to contaminated water at his source of employment. An intensive epidemiological investigation, including serological examination of all family members and pets and cultures on the patient and his family pets (cats and dogs), proved that the leptospiral organism was acquired by the patient's exposure to his dogs. The risk of acquiring infection from dogs that are asymptomatic and vaccinated is emphasized by this report. AD - Department of Internal Medicine, Wilford Hall US Air Force Medical Center, Lackland Air Force Base, TX 78236-5300. PMID- 2764659 SO - Arch Intern Med 1989 Aug;149(8):1878-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 89307588 AU - del Real G AU - Segers RP AU - van der Zeijst BA AU - Gaastra W TI - Cloning of a hemolysin gene from Leptospira interrogans serovar hardjo. LA - Eng MH - Cloning, Molecular MH - DNA, Bacterial/isolation & purification MH - *Genes, Bacterial MH - *Genes, Structural MH - Hemolysins/*genetics MH - Leptospira interrogans/*genetics MH - Support, Non-U.S. Gov't MH - Virulence RN - 0 (DNA, Bacterial) RN - 0 (Hemolysins) PT - JOURNAL ARTICLE DA - 890818 DP - 1989 Aug IS - 0019-9567 TA - Infect Immun PG - 2588-90 SB - M SB - X CY - UNITED STATES IP - 8 VI - 57 JC - GO7 AA - Author EM - 8910 AB - A DNA fragment encoding both hemolysin and sphingomyelinase C activity was cloned from the pathogenic bacterium Leptospira interrogans serovar hardjo. Initial clones were obtained by screening a genomic library in EMBL3 for hemolytic activity. Both hemolytic and sphingomyelinase C activities were coded for by a 3.9-kilobase BamHI fragment. The hemolysin was expressed from its own promoter in Escherichia coli K-12. Similar DNA sequences were also present in the serovars tarassovi and ballum. AD - Department of Bacteriology, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands. PMID- 2744864 CU - 91 SO - Infect Immun 1989 Aug;57(8):2588-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 89307571 AU - Masuzawa T AU - Nakamura R AU - Shimizu T AU - Iwamoto Y AU - Morita T AU - Yanagihara Y TI - Immunological characteristics of the glycolipid antigen of Leptospira interrogans serovar lai. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Antibodies, Monoclonal/biosynthesis MH - Antigens, Bacterial/administration & dosage/immunology/*isolation & purification MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Glycolipids/immunology/*isolation & purification MH - Hamsters MH - Leptospira interrogans/*immunology MH - Male MH - Mesocricetus MH - Mice MH - Mice, Inbred Strains MH - Opsonins/biosynthesis MH - Support, Non-U.S. Gov't MH - Weil's Disease/prevention & control RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Glycolipids) RN - 0 (Opsonins) PT - JOURNAL ARTICLE DA - 890818 DP - 1989 Aug IS - 0019-9567 TA - Infect Immun PG - 2502-6 SB - M SB - X CY - UNITED STATES IP - 8 VI - 57 JC - GO7 AA - Author EM - 8910 AB - The protective antigen (PAg), a glycolipid substance, was extracted from Leptospira interrogans serovar lai strain 017 with a chloroform- methanol-water (1:2:0.8 [vol/vol/vol]) solution and partially purified by silica gel column chromatography. The PAg was not detected by Coomassie brilliant blue staining in sodium dodecyl sulfate- polyacrylamide gel electrophoresis but was observed as a smearlike band, which corresponded to a 24- to 30-kilodalton standard protein, by silver staining. The outer envelope (OE) fraction showed the same band, suggesting that the PAg was one of the chemical components of the OE. The immunogenicity and protective activity of the PAg were compared with those of the OE. The PAg as well as the OE and whole cells was able to induce agglutinating antibody against L. interrogans. Furthermore, the immune sera exhibited opsonic activity against L. interrogans, as observed by measurement of chemical luminescence derived from reactive oxygen. The PAg exhibited protective activity in hamsters challenged with lethal doses of L. interrogans. Therefore, the antigen may be useful as a component vaccine against leptospiral infection. AD - Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka, Japan. PMID- 2744857 CU - 92 SO - Infect Immun 1989 Aug;57(8):2502-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 89342567 AU - Everard CO AU - Ferdinand GA AU - Butcher LV AU - Everard JD TI - Leptospirosis in piggery workers on Trinidad. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Dogs MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/epidemiology/parasitology/*transmission MH - Male MH - Middle Age MH - Occupational Diseases/parasitology MH - Support, Non-U.S. Gov't MH - Swine MH - Time Factors MH - Trinidad and Tobago PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW OF REPORTED CASES DA - 890921 DP - 1989 Aug IS - 0022-5304 TA - J Trop Med Hyg PG - 253-8 SB - M CY - ENGLAND IP - 4 VI - 92 JC - KAV AA - Author EM - 8911 AB - Of 133 cases of human leptospirosis recorded in Trinidad between 1977 and the end of February 1982, at least eight (6%) were in people who worked on pig farms. Three of the eight died, and their presumptive infecting serogroups were Icterohaemorrhagiae (3), Canicola (2), Pyrogenes (2) and Grippotyphosa (1). Six of the eight cases were followed up. Altogether, sera from 201 pigs, 78 other livestock animals, 38 workers and 34 dogs were tested for leptospiral agglutinins. The seropositivity prevalence among pigs on farms with human illness (43% greater than or equal to 1:100) was similar to that in pigs from farms not associated with illness (46%), but the titres among the former group (geometric mean 209.5) were higher than among the latter (91.5), where only titres less than or equal to 1:400 were recorded. Similar infecting serogroups were recorded among pigs on the two groups of farms, with Icterohaemorrhagiae, Autumnalis, Canicola and Pyrogenes most frequently recorded overall. There was little evidence of the pig-adapted serogroups Pomona and Tarassovi. Twelve of 13 workers (93%) from a farm on which at least two other people had contracted leptospirosis had serological evidence of exposure, compared with seven of 24 (29%) on a neighbouring farm not associated with human illness. Dogs and rodents are thought to be the major sources of leptospirosis in pigs and piggery workers in Trinidad. AD - MRC/Barbados Govt. Leptospira Laboratory, Bridgetown. RF - 17 PMID- 2668549 CU - 90 SO - J Trop Med Hyg 1989 Aug;92(4):253-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 90048215 AU - Barido ME AU - Alexanderson E AU - Halabe J AU - Castro G AU - Caballero A TI - [Weil's disease: report on 5 cases in the valley of Mexico] LA - Spa MH - Adult MH - Aged MH - Case Report MH - English Abstract MH - Female MH - Human MH - Male MH - Mexico MH - Middle Age MH - Risk Factors MH - Socioeconomic Factors MH - Weil's Disease/*complications/epidemiology/transmission PT - JOURNAL ARTICLE DA - 891206 DP - 1989 Jul-Sep IS - 0034-8376 TA - Rev Invest Clin PG - 253-7 CY - MEXICO IP - 3 VI - 41 JC - SCH AA - Author EM - 9002 AB - Leptospirosis, an acute generalized infection transmitted to humans from wild or domestic mammals, is rarely found in urban areas. We report here our experience with five cases of confirmed leptospirosis in the urban area of Mexico City. All five patients had epidemiologic risk factors, fever and a multisystemic illness, and two underwent laparotomy for acute abdominal syndrome. One patient died and four recovered completely. Problems in clinical and laboratory diagnosis are discussed. Leptospirosis should be suspected in patients with fever, jaundice and multiorgan involvement, and a proper epidemiologic setting. PMID- 2814000 TT - Enfermedad de Weil: informe de 5 casos en el valle de Mexico. EA - A SO - Rev Invest Clin 1989 Jul-Sep;41(3):253-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 90035151 AU - Premlatha MM AU - Srivastava SK TI - Characterization of trypsin extractable antigens of Leptospira interrogans serovars pomona, bataviae & L. biflexa serovar patoc. LA - Eng MH - Agglutination Tests MH - Antigens, Bacterial/*isolation & purification MH - Leptospira/classification/*immunology MH - Leptospira interrogans/classification/immunology MH - Trypsin RN - EC 3.4.21.4 (Trypsin) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 891212 DP - 1989 Jul IS - 0019-5340 TA - Indian J Med Res PG - 249-54 CY - INDIA VI - 89 JC - GJF AA - Author EM - 9002 AB - Leptospira strains after treatment with trypsin released an antigen (Tx) which consisted of protein (4.2 mg/ml), carbohydrate (0.39 mg/ml) and hexosamine (0.025 mg/ml). Immunodiffusion, immunoelectrophoresis and indirect haemagglutination tests revealed serological cross reactions among the three strains used. Inhibition of microscopic agglutination reaction by the Tx antigen was observed in homologous system only. The antigen was partially sensitive to heat (80 degrees C for 10 min) as detected by immunodiffusion and microscopic agglutination inhibition. These data revealed the presence of serovar- specific and genus-specific antigens on Leptospira strains. It is suggested that this antigen could be useful in developing a serodiagnostic test for leptospirosis. PMID- 2807430 CU - 91 SO - Indian J Med Res 1989 Jul;89:249-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 89389226 AU - van den Ingh TS AU - Hartman EG AU - Bercovich Z TI - Clinical Leptospira interrogans serogroup Australis serovar lora infection in a stud farm in The Netherlands. LA - Eng MH - Animal MH - Disease Outbreaks/*veterinary MH - Female MH - Horse Diseases/*epidemiology/microbiology/pathology MH - Horses MH - Kidney/pathology MH - Leptospira interrogans/isolation & purification MH - Lung/pathology MH - Netherlands MH - Weil's Disease/epidemiology/microbiology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 891017 DP - 1989 Jul IS - 0165-2176 TA - Vet Q PG - 175-82 SB - M CY - NETHERLANDS IP - 3 VI - 11 JC - XBT AA - Author EM - 8912 AB - A Leptospira interrogans serogroup australis serovar lora infection in a stud farm is reported. During three successive years (1984-1986) clinical leptospirosis with a severe often rapid, fatal course was seen in 12 foals. Clinical examination revealed severe respiratory distress, depression and pyrexia. Other symptoms were diarrhea (2), jaundice (1), and an unsteady gait (1). Morphological characteristics of the disease were massive pulmonary haemorrhage and haemorrhagic-thrombotic or extracapillary glomerulonephritis with tubulonephrosis and interstitial oedema. In most foals high or increasing MAT titres to serovar bratislava were found; from one foal Leptospira interrogans serovar lora was isolated. Serological examination of all 56 mares at the farm (August 1986) revealed antibodies to serovar bratislava in 64 per cent of the animals. These findings support the idea that Leptospira interrogans serovar bratislava and closely related strains (in this study serovar lora) may be adapted to and maintained by the horse population. AD - Department of Veterinary Pathology, Faculty of Veterinary Medicine, State University Utrecht, The Netherlands. PMID- 2781710 SO - Vet Q 1989 Jul;11(3):175-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 89384928 AU - Terpstra WJ AU - Korver H AU - Schonemann C AU - Gravekamp C TI - [Weil's disease, milker's fever and other leptospiroses, 1981-1987] LA - Dut MH - Agricultural Workers' Diseases/epidemiology MH - Animal MH - Dairying MH - English Abstract MH - Human MH - Leptospirosis/diagnosis/*epidemiology/transmission MH - Netherlands MH - Seasons MH - Weil's Disease/diagnosis/*epidemiology/transmission MH - Zoonoses PT - JOURNAL ARTICLE DA - 891025 DP - 1989 Jul 1 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 1322-6 CY - NETHERLANDS IP - 26 VI - 133 JC - NUK AA - Author EM - 8912 AB - In The Netherlands, human leptospirosis is mainly caused by the serovars icterohaemorrhagiae and copenhageni, both of which belong to the Icterohaemorrhagiae group and originate from rats, serovars hardjo from cattle and grippotyphosa from voles. In 1981-1987, 175 cases of leptospirosis were registered. In 17 of these cases the infection was acquired outside The Netherlands. Infections caused by serovars from the Icterohaemorrhagiae group were mainly observed in the province of Zuid-Holland, hardjo infections in the province of Friesland. The number of hardjo infections increased. Hardjo also causes problems in cattle. Infections caused by serovars icterohaemorrhagiae and copenhageni were mainly associated with exposure to inland surface waters in relation with recreational or professional activities or accidents. Hardjo infections were characteristically associated with dairy farming. The incidences of all types of leptospirosis were highest in late summer and early autumn. PMID- 2779678 TT - Ziekte van Weil, melkerskoorts en andere leptospirosen, 1981-1987. EA - A SO - Ned Tijdschr Geneeskd 1989 Jul 1;133(26):1322-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 89375953 AU - Arimitsu Y AU - Haritani K AU - Ishiguro N AU - Kobayashi S TI - Detection of antibodies to leptospirosis in experimentally infected dogs using the microcapsule agglutination test. LA - Eng MH - Agglutination Tests/*veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Capsules MH - Dog Diseases/diagnosis/*immunology MH - Dogs MH - IgM/analysis MH - Leptospira interrogans/*immunology MH - Leptospirosis/diagnosis/immunology/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Capsules) PT - JOURNAL ARTICLE DA - 891023 DP - 1989 Jul-Aug IS - 0007-1935 TA - Br Vet J PG - 356-61 CY - ENGLAND IP - 4 VI - 145 JC - B5C AA - Author EM - 8912 AB - Six puppies were infected with a virulent strain of Leptospira interrogans serovar icterohaemorrhagiae and another five animals with a virulent strain of Leptospira interrogans serovar canicola, respectively. Antibodies were examined at 3, 5, 7, 11 and 14 days after infection, using the microcapsule agglutination test (MCAT) and the conventional microscopic agglutination test (MAT). Compared with the MAT, the MCAT detected early specific IgM antibody with high sensitivity. The MCAT titres reached a peak at the 7th day after infection and declined gradually after the 11th day, while the MAT titres increased up to the 14th day. PMID- 2775983 CU - 91 SO - Br Vet J 1989 Jul-Aug;145(4):356-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 89374500 AU - Isogai E AU - Kitagawa H AU - Isogai H AU - Matsuzawa T AU - Shimizu T AU - Yanagihara Y AU - Katami K TI - Effects of leptospiral lipopolysaccharide on rabbit platelets. LA - Eng MH - Adenosine Triphosphate/metabolism MH - Animal MH - Blood Platelets/metabolism/ultrastructure MH - Female MH - In Vitro MH - Leptospira interrogans/*physiology MH - Lipopolysaccharides/*physiology MH - Male MH - *Platelet Aggregation MH - Rabbits MH - Serotonin/metabolism MH - Thrombocytopenia/etiology RN - 0 (Lipopolysaccharides) RN - 50-67-9 (Serotonin) RN - 56-65-5 (Adenosine Triphosphate) PT - JOURNAL ARTICLE DA - 891023 DP - 1989 Jul IS - 0934-8840 TA - Zentralbl Bakteriol PG - 186-96 SB - M CY - GERMANY IP - 2 VI - 271 JC - BD7 AA - Author EM - 8912 AB - Leptospiral lipopolysaccharides (LPSs) extracted from Leptospira interrogans serovar copenhageni virulent strain Shibaura, serovar canicola virulent strain Moulton, and serovar hebdomadis strain Hebdomadis, were tested for their ability to induce platelet aggregation and/or lysis in rabbit platelet-rich plasma (PRP). All showed positive reactions with a release of adenosine triphosphate (ATP) and serotonin. The values, however, were different from each other. The ability of leptospiral LPS extracted from serovar copenhageni virulent strain Shibaura (I-LPS) to induce platelet aggregation was the highest of all. After treatment of I-LPS, the platelets developed a ruffled surface with appearance of pseudopodia as observed by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). I-LPS also showed cytotoxicity for the platelets. Degenerative or lytic changes were recognized in 44.5% of the platelets which were observed 60 min after I-LPS treatment. AD - Dept. of Preventive Dentistry, School of Dentistry, Higashi Nippon Gakuen Univ., Hokkaido, Japan. RO - M:CNR PMID- 2775427 LR - 970304 CU - 91 SO - Zentralbl Bakteriol 1989 Jul;271(2):186-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 89372396 AU - Frantz JC AU - Hanson LE AU - Brown AL TI - Effect of vaccination with a bacterin containing Leptospira interrogans serovar bratislava on the breeding performance of swine herds. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacterial Vaccines MH - Female MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/prevention & control/*veterinary MH - Pregnancy MH - *Reproduction MH - Swine MH - Swine Diseases/immunology/*prevention & control MH - Vaccination/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 891005 DP - 1989 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1044-7 SB - M CY - UNITED STATES IP - 7 VI - 50 JC - 40C AA - Author EM - 8912 AB - Swine herds suspected to be infected with Leptospira interrogans serovar bratislava were vaccinated with bacterins containing 5 or 6 leptospiral serovars in which serovar bratislava was the unique component. The principal diagnostic feature indicating an infection by this organism was demonstration of antibody against serovar bratislava in sera from stillborn pigs. For 1 breeding cycle after vaccination of herds on 3 farms, 255 of 266 (95.9%) sows and gilts given the 6-serovar bacterin farrowed. In contrast, 233 of 311 (74.9%) sows and gilts given the 5-serovar bacterin farrowed. These results, as evaluated by analysis of variance techniques, showed a significant improvement (P less than 0.01) in reproductive performance for groups vaccinated against serovar bratislava. AD - Norden Laboratories Inc, Lincoln NE 68501. PMID- 2774321 CU - 91 SO - Am J Vet Res 1989 Jul;50(7):1044-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 89368395 AU - McCormick BM AU - Millar BD AU - Monckton RP AU - Jones RT AU - Chappel RJ AU - Adler B TI - Detection of leptospires in pig kidney using DNA hybridisation. LA - Eng MH - Abattoirs MH - Animal MH - DNA, Bacterial/*analysis MH - Kidney/*microbiology MH - Leptospira interrogans/genetics/*isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - Nucleic Acid Hybridization MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*microbiology RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 890925 DP - 1989 Jul IS - 0034-5288 TA - Res Vet Sci PG - 134-5 SB - M CY - ENGLAND IP - 1 VI - 47 JC - R7D AA - Author EM - 8912 AB - DNA hybridisation detected leptospiral organisms in homogenised kidneys from experimentally infected pigs, and in homogenates of pig kidneys collected at abattoirs. The technique is easy to perform and had some advantages over cultural and histological methods, in permitting the rapid survey of many kidneys simultaneously. Leptospires added to a homogenate of uninfected kidney could be detected at 10(2) organisms ml- 1 by DNA hybridisation, but the technique appeared to be less sensitive than culture. AD - Department of Agriculture and Rural Affairs, Regional Veterinary Laboratory, Bendigo, Victoria, Australia. PMID- 2772401 CU - 91 SO - Res Vet Sci 1989 Jul;47(1):134-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 89354063 AU - Baker TF AU - McEwen SA AU - Prescott JF AU - Meek AH TI - The prevalence of leptospirosis and its association with multifocal interstitial nephritis in swine at slaughter. LA - Eng MH - Animal MH - Leptospirosis/complications/epidemiology/pathology/*veterinary MH - Nephritis, Interstitial/complications/epidemiology/pathology/*veterinary MH - Ontario MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*epidemiology/microbiology/pathology PT - JOURNAL ARTICLE DA - 890926 DP - 1989 Jul IS - 0830-9000 TA - Can J Vet Res PG - 290-4 SB - M CY - CANADA IP - 3 VI - 53 JC - CKL AA - Author EM - 8912 AB - An abattoir survey was undertaken to determine the prevalence of leptospirosis and its association with lesions of multifocal interstitial nephritis (so-called "white spotted kidneys") in swine at slaughter. Both cross-sectional and case-control study designs were used. Of 197 kidneys from hogs randomly selected at slaughter, 11 (5.6%) had generalized grey-white foci typical of multifocal interstitial nephritis (MFIN). Antibody titers greater than or equal to 1:80 against Leptospira pomona were detected in nine (4.6%) hogs and against L. bratislava in 63 (32%) of these hogs. Leptospira pomona (kennewicki) was detected by immunofluorescence in 5/197 (2.5%) of randomly selected hogs. Leptospires identified as genotype kennewicki were isolated from six (9.8%) of 61 kidneys cultured. Leptospira bratislava was not detected by immunofluorescence or culture. There was a highly significant (p = 0.00) and strong association (odds ratio (OR) = 195) between high L. pomona titer (greater than or equal to 1:80) and the presence of leptospires in the kidneys, as detected by culture. There was also a significant (p = 0.046) and strong (OR = 8.10) association between multifocal interstitial nephritis and the presence of renal leptospires as detected by culture. The association between leptospiral titer and MFIN lesions in the prevalence survey group of animals was statistically significant (p = 0.031), but this association was not significant in the case-control study group (p = 0.071) The failure to identify L. bratislava despite serological evidence of infection suggests that some of these seropositive animals may have been transiently infected at an early age, that serological findings were falsely positive, or that immunofluorescence and isolation attempts failed to detect L. bratislava if they were indeed present in the kidneys.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Veterinary Microbiology and Immunology, Ontario Veterinary College, University of Guelph. PMID- 2766150 SO - Can J Vet Res 1989 Jul;53(3):290-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 89354062 AU - Cho HJ AU - Gale SP AU - Masri SA AU - Malkin KL TI - Diagnostic specificity, sensitivity and cross-reactivity of an enzyme- linked immunosorbent assay for the detection of antibody against Leptospira interrogans serovars pomona, sejroe and hardjo in cattle. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle/*immunology MH - Cattle Diseases/*diagnosis/immunology/microbiology MH - Enzyme-Linked Immunosorbent Assay MH - Leptospira interrogans/*immunology MH - Leptospirosis/diagnosis/immunology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890926 DP - 1989 Jul IS - 0830-9000 TA - Can J Vet Res PG - 285-9 SB - M CY - CANADA IP - 3 VI - 53 JC - CKL AA - Author EM - 8912 AB - Outer sheath antigen was prepared from Leptospira interrogans serovars pomona, sejroe and hardjo by treating the organisms with 1.0M NaC1 followed by 0.04% sodium dodecyl sulfate (SDS). Sodium dodecyl sulfate was removed from the SDS-protein complexes by the extraction of dodecyl sulfate anions as ion pairs with triethylammonium cations into an organic solvent. The outer sheath antigen was recovered from the organic solvent as a precipitate and used as the source of leptospiral enzyme-linked immunosorbent assay (ELISA) antigen. Utilizing this antigen, ELISA was adapted to detect bovine serum antibody to L. interrogans serovars pomona, sejroe and hardjo. The specificity of this assay in 344 bovine sera, which were negative in the microscopic agglutination test (MAT) for seven serovars, was 99.4%. In sera from 37 and 87 cattle which revealed MAT titers greater than or equal to 1:50 for L. interrogans serovars pomona and sejroe, the relative sensitivity of the test was 100%. The ELISA also showed a considerable degree of low level cross-reactivity with other serovars. Sixty-six (75.9%) out of 87 bovine sera which were MAT-positive (MAT titer of greater than or equal to 1:50) with serovars sejroe and hardjo only were ELISA positive with heterologous pomona antigen; 16 (43.2%) and six 16.2%) out of 37 bovine sera which were MAT positive MAT titer of greater than or equal to 1:50) with serovar pomona only were ELISA positive with heterologous sejroe and hardjo ELISA antigen respectively.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Agriculture Canada, Animal Diseases Research Institute, Lethbridge, Alberta. PMID- 2766149 CU - 91 SO - Can J Vet Res 1989 Jul;53(3):285-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 90052081 AU - Sergeev AA AU - Chernukha IuG AU - Shakhanina KL AU - Gol'denshtein ZA AU - Potashnikova EIa TI - [The diagnosis of antileptospiral antibodies in human subjects by solid- phase immunoenzyme analysis] LA - Rus MH - Antibodies, Bacterial/*analysis MH - Antibody Specificity MH - Antigens, Bacterial/analysis/isolation & purification MH - Blood Donors MH - Comparative Study MH - English Abstract MH - Evaluation Studies MH - Hepatitis/diagnosis MH - Human MH - Immunoenzyme Techniques MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Syphilis Serodiagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 891212 DP - 1989 Jul IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 66-71 SB - M CY - USSR IP - 7 JC - Y9O AA - Author EM - 9002 AB - The possibility of using the enzyme-linked immunosorbent assay (ELISA) for the diagnosis of leptospirosis has been shown. This method has proved to be more simple and sensitive than the leptospiral microagglutination and lysis test. The data on obtaining genus-specific leptospiral antigens are presented. As revealed in this study, the antigens obtained by the complex treatment of microbial cells with ultrasound and detergents show the maximum activity in ELISA. The optimum parameters of the ELISA system for the diagnosis of leptospirosis have been established. PMID- 2683525 CU - 91 TT - Diagnostika protivoleptospiroznykh antitel u liudei metodom tverdofaznogo immunofermentnogo analiza. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1989 Jul;(7):66-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 89372389 AU - Bolin CA AU - Zuerner RL AU - Trueba G TI - Comparison of three techniques to detect Leptospira interrogans serovar hardjo type hardjo-bovis in bovine urine. LA - Eng MH - Animal MH - Bacteriuria/diagnosis/*veterinary MH - Cattle MH - Cattle Diseases/*diagnosis MH - Comparative Study MH - Female MH - Fluorescent Antibody Technique/veterinary MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - Male MH - Nucleic Acid Hybridization MH - Pregnancy MH - Pregnancy Complications, Infectious/diagnosis/*veterinary MH - Serotyping MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 891005 DP - 1989 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1001-3 SB - M CY - UNITED STATES IP - 7 VI - 50 JC - 40C AA - Author EM - 8912 AB - Nucleic acid hybridization, bacteriologic culture, and a fluorescent antibody test were compared for detection of Leptospira interrogans serovar hardjo type hardjo-bovis in bovine urine. Seventy-five urine samples were collected from pregnant cows challenge exposed with type hardjo-bovis. Twenty samples were collected from steers not exposed to hardjo-bovis. Sediments from each sample were examined, using fluorescent antibodies and a repetitive sequence element nucleic acid probe, to detect the presence of leptospires. Urine samples were processed for bacteriologic culture, using standard techniques. Under laboratory conditions typically used for these techniques, leptospires were detected in 60 of 75 urine samples from challenge exposed cows by nucleic acid hybridization, in 24 samples by fluorescent antibody test, and in 13 samples by bacteriologic culture. Leptospires were not detected in the urine of steers not exposed to hardjo-bovis. AD - USDA, National Animal Disease Center, Ames, IA 50010. PMID- 2672910 CU - 90 SO - Am J Vet Res 1989 Jul;50(7):1001-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 90176285 AU - Santos RT AU - Sakata EE AU - Yasuda PH AU - Wakamatsu A AU - Kanamura CT AU - Candelori I AU - Pestana CB AU - Alves VA TI - [Glycoproteins from Leptospira interrogans serogroup icterohaemorrhagiae: distribution in the liver and kidney of experimentally infected guinea pigs] LA - Por MH - Animal MH - Bacterial Proteins/analysis/*toxicity MH - English Abstract MH - Glycoproteins/analysis/*toxicity MH - Guinea Pigs MH - Kidney/analysis MH - Leptospira interrogans/*analysis MH - Liver/analysis MH - Weil's Disease/*etiology RN - 0 (Bacterial Proteins) RN - 0 (Glycoproteins) PT - JOURNAL ARTICLE DA - 900402 DP - 1989 Jul-Aug IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 235-41 CY - BRAZIL IP - 4 VI - 31 JC - S9D AA - Author EM - 9006 AB - Tissue damage in leptospirosis has been ascribed to direct effect of the microorganisms and/or their virulence, including products synthetized by leptospires or released during their lysis. This study aimed at chemical extraction of the glycolipoprotein (GLP) from virulent leptospires, production of a rabbit anti-GLP and analysis of its distribution in liver and kidney of inoculated guinea-pigs, sacrificed sequentially from the 1st to 6th day of infection, covering the whole, spectrum of acute leptospirosis. The comparison of GLP expression to local injuries aimed at new pathogenetic data. GLP was detected in liver and kidney in 2 out of 6 guinea-pigs on the 5th day and in all 6 animals on the 6th day of infection. Granular forms were seen in the cytoplasm of macrophages, free in interstitium or adhered to endothelial and parenchymal cell membranes, especially in the most damaged sites. These findings lead us to the hypothesis of GLP as a toxic factor resulting from leptospiral lysis by macrophages. Although it was not proved as a promoter of initial lesions, it seems to be related to the enhancement of tissue damage late in the course of the disease. PMID- 2626644 CU - 91 TT - Glicolipoproteina de Leptospira interrogans sorogrupo icterohaemorrhagiae: distribuicao em figado e rim de cobaias experimentalmente infectadas. EA - A SO - Rev Inst Med Trop Sao Paulo 1989 Jul-Aug;31(4):235-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 90130241 AU - Muthusethupathi MA AU - Shivakumar S TI - Leptospirosis--need for urgent action [letter] LA - Eng MH - *Developing Countries MH - Human MH - India MH - Leptospirosis/*diagnosis/epidemiology/prevention & control PT - LETTER DA - 900312 DP - 1989 Jul IS - 0004-5772 TA - J Assoc Physicians India PG - 477 CY - INDIA IP - 7 VI - 37 JC - HG7 EM - 9005 PMID- 2613671 CU - 91 SO - J Assoc Physicians India 1989 Jul;37(7):477 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 89311385 AU - Ong LY AU - Pang T AU - Lim SH AU - Tan EL AU - Puthucheary SD TI - A simple adherence test for detection of IgM antibodies in typhoid. LA - Eng MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/*immunology MH - Cross Reactions MH - Human MH - IgM/*analysis MH - Immunoassay MH - Salmonella typhi/*immunology MH - Support, Non-U.S. Gov't MH - Typhoid/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (H antigen) RN - 0 (O Antigens) PT - JOURNAL ARTICLE DA - 890814 DP - 1989 Jul IS - 0022-2615 TA - J Med Microbiol PG - 195-8 SB - M CY - ENGLAND IP - 3 VI - 29 JC - J2N AA - Author EM - 8910 AB - A simple adherence test to detect IgM antibodies in patients with typhoid is described. The test utilises the IgM-"capture" approach, in which the test serum is applied to microtitration plate wells previously coated with anti-human IgM, followed by application of a stained Salmonella typhi antigen suspension which shows adherence in positive cases. By this test, 58 (95%) of 61 sera from confirmed cases of typhoid possessed IgM antibodies to the H or O or both antigens of S. typhi. In patients for whom a diagnosis of typhoid was based only on a significant Widal-test titre, 31 (41%) of 76 sera had IgM antibodies to the H or O or both antigens of S. typhi. Some cross-reactivity of the IgM antibodies was detected, especially with the O antigens of S. paratyphi A and B. A total of 82 sera from non-typhoidal fevers (leptospirosis, typhus, dengue fever) showed no reactivity in this test. In normal sera there was no detectable IgM to the O antigen of S. typhi and only a small number (3.9%) had low levels of IgM to the H antigen. The significance and potential importance of this simple, sensitive, specific and economical test is discussed. AD - Department of Genetics and Cellular Biology, University of Malaya, Kuala Lumpur. PMID- 2473209 CU - 95 SO - J Med Microbiol 1989 Jul;29(3):195-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 89370056 AU - Pritchard GC AU - Borland ED AU - Wood L AU - Pritchard DG TI - Severe disease in a dairy herd associated with acute infection with bovine virus diarrhoea virus, Leptospira harjo and Coxiella burnetii. LA - Eng MH - Abortion, Veterinary/etiology MH - Acute Disease MH - Animal MH - Bovine Virus Diarrhea-Mucosal Disease/complications/*epidemiology MH - Cattle MH - Cattle Diseases/*epidemiology/etiology MH - Disease Outbreaks/*veterinary MH - Female MH - Fetal Death/etiology/veterinary MH - Leptospirosis/complications/epidemiology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/veterinary MH - Q Fever/complications/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 890922 DP - 1989 Jun 17 IS - 0042-4900 TA - Vet Rec PG - 625-9 SB - M CY - ENGLAND IP - 24 VI - 124 JC - XBS AA - Author EM - 8912 AB - Between November 1984 and February 1985, a serious outbreak of pyrexia, diarrhoea, agalactia, metritis and severe weight loss affected most of the recently calved cows in a 183-cow dairy herd in Norfolk. Fifteen cows died and 20 were culled. Forty cows aborted during or after the outbreak, and many of them produced mummified fetuses; 18 calves were stillborn and three others died soon after birth. Necropsy of three affected cows revealed ulceration of the gastrointestinal tract similar to that seen in cases of mucosal disease. Bovine virus diarrhoea virus was isolated from the intestines of one cow that died soon after the onset of illness. The virus was also isolated from the blood of four acutely ill cows and seroconversion was demonstrated in three of those that survived. The virus was isolated from three aborted fetuses, a stillborn calf and a live neonatal calf. Body fluids from two aborted fetuses were seropositive for the virus as were sera from all the aborting cows tested. In addition to widespread seroconversion to bovine virus diarrhoea virus during the outbreak, there was serological evidence of recent infection with Leptospira interrogans serovar hardjo and Coxiella burnetii in a high proportion of cows. It was concluded that this was primarily an acute outbreak of bovine virus diarrhoea but its unprecedented clinical severity was probably associated with the concurrent introduction of L hardjo and C burnetii into an immunologically naive herd during the main calving period. Epidemiological analysis suggested that the source of the virus and L hardjo was down-calving heifers returning from communal marsh grazing. AD - Veterinary Investigation Centre, Norwich, Norfolk. PMID- 2773203 CU - 90 SO - Vet Rec 1989 Jun 17;124(24):625-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 89373845 AU - Silbreck NW AU - Davies WD TI - Restriction endonuclease analysis of Australian isolates of Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Australia MH - Cattle MH - Comparative Study MH - Deoxyribonuclease EcoRI MH - Deoxyribonucleases, Type II Site-Specific MH - DNA, Bacterial/*analysis MH - Genotype MH - Leptospira interrogans/*classification/genetics MH - Restriction Mapping MH - Serotyping MH - Species Specificity MH - Support, Non-U.S. Gov't RN - EC 3.1.21.- (endodeoxyribonuclease HhaI) RN - EC 3.1.21.- (Deoxyribonuclease EcoRI) RN - EC 3.1.21.4 (Deoxyribonucleases, Type II Site-Specific) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 891011 DP - 1989 Jun IS - 0005-0423 TA - Aust Vet J PG - 183-4 SB - M CY - AUSTRALIA IP - 6 VI - 66 JC - 9IE EM - 8912 AD - Victorian Department of Agriculture and Rural Affairs, Veterinary Research Institute. PMID- 2789036 CU - 91 SO - Aust Vet J 1989 Jun;66(6):183-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 89323708 AU - Mumford CJ TI - Leptospirosis and water sports [editorial] [see comments] LA - Eng MH - Great Britain MH - Health Education MH - Human MH - Leptospirosis/diagnosis/*epidemiology/transmission MH - *Sports MH - *Water RN - 7732-18-5 (Water) PT - EDITORIAL DA - 890907 DP - 1989 Jun IS - 0007-1064 TA - Br J Hosp Med PG - 519 SB - M CY - ENGLAND IP - 6 VI - 41 JC - BZ5 EM - 8911 CM - Comment in: Br J Hosp Med 1989 Oct;42(4):340 RO - M:LC1 PMID- 2752238 LR - 900305 CU - 91 SO - Br J Hosp Med 1989 Jun;41(6):519 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 89285274 AU - Krane NK AU - Roland P AU - Herrera G TI - Acute renal failure in a jaundiced patient. LA - Eng MH - Case Report MH - Consciousness MH - Diagnosis, Differential MH - Glomerulonephritis/diagnosis MH - Human MH - Hypoproteinemia/etiology MH - Jaundice/*etiology MH - Kidney Failure, Acute/diagnosis/*etiology MH - Kidney Tubular Necrosis, Acute/diagnosis MH - Leptospirosis/complications/*diagnosis/metabolism MH - Male MH - Middle Age MH - Nephritis, Interstitial/diagnosis MH - Serum Albumin/deficiency RN - 0 (Serum Albumin) PT - JOURNAL ARTICLE DA - 890718 DP - 1989 Jun IS - 0002-9629 TA - Am J Med Sci PG - 394-8 SB - A SB - M CY - UNITED STATES IP - 6 VI - 297 JC - 3L2 EM - 8909 AD - Tulane University School of Medicine, Tulane Department of Medicine, Charity Hospital, New Orleans, Louisiana. PMID- 2735345 CU - 91 SO - Am J Med Sci 1989 Jun;297(6):394-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 89279873 AU - Jost BH AU - Adler B AU - Faine S TI - Experimental immunisation of hamsters with lipopolysaccharide antigens of Leptospira interrogans. LA - Eng MH - Acetylmuramyl-Alanyl-Isoglutamine/immunology MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Hamsters MH - IgG/biosynthesis MH - IgM/biosynthesis MH - *Immunization MH - Leptospira interrogans/*immunology MH - Lipopolysaccharides/*immunology MH - Mesocricetus MH - Polysaccharides, Bacterial/immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/*prevention & control RN - 0 (Antibodies, Bacterial) RN - 0 (Lipopolysaccharides) RN - 0 (Polysaccharides, Bacterial) RN - 53678-77-6 (Acetylmuramyl-Alanyl-Isoglutamine) PT - JOURNAL ARTICLE DA - 890714 DP - 1989 Jun IS - 0022-2615 TA - J Med Microbiol PG - 115-20 SB - M CY - ENGLAND IP - 2 VI - 29 JC - J2N AA - Author EM - 8909 AB - Hamsters were immunised with leptospiral lipopolysaccharide (LPS) or the polysaccharide (PS) fraction of LPS from Leptospira interrogans serovar copenhageni and the antibody responses were measured by agglutination tests. Maximum titres were observed approximately 6 weeks after immunisation and protection against lethal challenge with the homologous strain was afforded by immunisation with as little as 2.5 micrograms of LPS or PS. All animals produced IgM agglutinins but a higher proportion of-animals immunised with PS produced IgG agglutinins than did those immunised with LPS. Immunisation of guinea-pigs with autoclaved PS showed that the preparation retained some but not all of its immunogenic activity. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 2733021 CU - 91 SO - J Med Microbiol 1989 Jun;29(2):115-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 90117258 AU - Watt G AU - Manaloto C AU - Hayes CG TI - Central nervous system leptospirosis in the Philippines. LA - Eng MH - Adult MH - Child MH - Child, Preschool MH - Encephalitis/etiology MH - Female MH - Human MH - Leptospira MH - *Leptospirosis MH - Male MH - Meningitis, Aseptic/etiology MH - Meningoencephalitis/*etiology MH - Philippines MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 900213 DP - 1989 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 265-9 SB - M CY - THAILAND IP - 2 VI - 20 JC - UVN AA - Author EM - 9004 AB - One hundred hospitalized patients in Manila, Philippines with aseptic meningoencephalitis were screened for leptospirosis. On the basis of a microscopic agglutination titer of 1:1,600 or greater, the diagnosis was made in five cases, yet in no instance had leptospirosis been included in the differential diagnosis on admission to the hospital. Four of the five patients first noted neurologic symptoms during the second week of illness; two patients presented with encephalitis, two with meningitis and the fifth with hemiparesis. No case was complicated by renal dysfunction or jaundice. By the time of discharge from the hospital, two patients had recovered completely and the other three had markedly improved. Our data show that leptospirosis is an important but overlooked cause of aseptic meningoencephalitis in the Philippines. This is probably also the case in other parts of the tropics where Leptospira interrogans infection remains a significant public health problem. AD - U.S. Naval Medical Research Unit No. 2, Manila, Philippines. PMID- 2609216 CU - 90 SO - Southeast Asian J Trop Med Public Health 1989 Jun;20(2):265-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [51 medline neighbors] UI - 90077357 AU - Bao L AU - Dai BM TI - [Endocytosis and cytotoxin effect induced by the attachment of the glycolipoprotein of leptospires to vascular endothelial cell in culture] LA - Chi MH - Animal MH - Attachment Sites (Microbiology) MH - Cattle MH - Cells, Cultured MH - Cytotoxins MH - *Endocytosis MH - Endothelium, Vascular/*cytology MH - English Abstract MH - *Glycoproteins MH - Leptospira/*pathogenicity MH - Leptospira interrogans/pathogenicity MH - Support, Non-U.S. Gov't RN - 0 (Cytotoxins) RN - 0 (Glycoproteins) PT - JOURNAL ARTICLE DA - 900125 DP - 1989 Jun IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 115-8 CY - CHINA IP - 2 VI - 20 JC - GEB AA - Author EM - 9003 AB - The Glycolipoprotein (GLP) of various virulent leptospires was extracted, purified and identified. The GLP was combined with fluorescence rhodamine B and the colloidal gold as the probe. Meanwhile, the bovine aortic endothelial cell (EN) was isolated and cultured in the medium 199 "Nissui". The GLP-rhodamine B and GLP- colloidal gold probe were added to cultured EN and incubated at 4 degrees C for 2 h then at 37 degrees C for 2 h. The interaction between GLP-rhodamine B, GLP-CG probe and EN were observed and photography by fluorescence microscopy (Leitz) and scanning electronmicroscopy. The releasing rate of lactic acid dehydrogenase (LDH), acid phosphatase (AcP) and protein from the EN were detected. The results indicated that the GLP of Leptospira interrogans serovar Lai, strain 017 attached to EN and a endocytosis was happened subsequently. The LDH and AcP releasing rate were significantly higher than control and the cell protein was much less than control. The results showed that the GLP of L. interrogans strain 017 had the cytotoxin effect through a specific attachment, endocytosis in EN. The endocytosis probably is a receptor- mediated endocytosis. PMID- 2591917 CU - 92 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1989 Jun;20(2):115-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 89373839 AU - Norton JH AU - Tranter WP AU - Campbell RS TI - A farming systems study of abortion in dairy cattle on the Atherton Tableland. 2. The pattern of infectious diseases. LA - Eng MH - Abortion, Veterinary/epidemiology/*etiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/analysis MH - Bacterial Infections/epidemiology/*veterinary MH - Bovine Virus Diarrhea-Mucosal Disease/epidemiology MH - Bunyaviridae Infections/epidemiology/veterinary MH - Cattle MH - Cattle Diseases/epidemiology/*etiology MH - Female MH - Infectious Bovine Rhinotracheitis/epidemiology MH - Leptospirosis/epidemiology/veterinary MH - Ornithosis/epidemiology/veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/epidemiology/veterinary MH - Queensland MH - Sarcocystosis/epidemiology/*veterinary MH - Support, Non-U.S. Gov't MH - Virus Diseases/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 891011 DP - 1989 Jun IS - 0005-0423 TA - Aust Vet J PG - 163-7 SB - M CY - AUSTRALIA IP - 6 VI - 66 JC - 9IE AA - Author EM - 8912 AB - The role of infectious agents on dairy farms on the Atherton Tableland in tropical north Queensland was studied as part of a comprehensive investigation into the causes of bovine abortion. The prevalence of antibody in serums collected from 7 herds whose annual abortion rates ranged from 3% to 21% were as follows: Leptospira hardjo 49.9% (426/853), L. pomona 0.4% (3/851), bovine virus diarrhoea (BVD) 33.7% (35/104). Infectious bovine rhinotracheitis virus (IBR) 11.5% (12/105), Akabane virus 92.2% (95/103), Aino virus 62.1% (64/103), Chlamydia psittaci 3.1% (37/1004), Brucella abortus 0% (0/851), and Toxoplasma gondii 0% (0/105). Testing of serums against a wide range of leptospiral serotypes indicated that reactions occurring in the Hebdomadis and Sejroe serogroups were probably cross reactions with L. hardjo. Infection with L. hardjo and Akabane virus occurred prior to first mating and contact with Aino virus occurred during first pregnancy. Infection with BVD and IBR viruses was sporadic. The pathology and microbiology of 32 aborted foetuses from 24 Tableland herds (10 from the group of 19 farms under more intense study) were performed. Lesions associated with a Sarcocystis-like agent were present in 6, leptospires in 1, suspected toxic hepatosis in 2 and purulent bronchopneumonia (Staphylococcus aureus) in 1 foetus. No diagnoses were made in the remaining 22 foetuses (69%). Evidence for a common infectious cause of abortion in the population was inconclusive. AD - Queensland Department of Primary Industries, Oonoonba Veterinary Laboratory, Townsville. PMID- 2505741 CU - 91 SO - Aust Vet J 1989 Jun;66(6):163-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 89298162 AU - Bricaire F TI - [Leptospirosis] LA - Fre MH - Antibiotics/therapeutic use MH - English Abstract MH - Human MH - Leptospira/classification MH - *Leptospirosis/diagnosis/drug therapy/epidemiology MH - Serotyping RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 890801 DP - 1989 May 18 IS - 0035-2640 TA - Rev Prat PG - 1308-12 CY - FRANCE IP - 15 VI - 39 JC - T1D AA - Author EM - 8910 AB - Recent epidemiological data show that leptospirosis is widespread in the animal kingdom, and not only among Muridae, and, that the number of human cases is greater than in the past while being still underestimated. To the classical occupational contaminations must now be added those due to water sports. Since leptospirosis has extremely diverse clinical features, physicians should have this diagnosis in mind in many circumstances and should request the appropriate examinations at the right moment. Carefully performed microbiological techniques may reduce the problems encountered in isolating leptospires. Serological tests requested after the 12th day of the disease and repeated several times should improve the diagnostic confirmation. The potential severity of certain forms justifies not only a curative antibiotic therapy, but also prophylactic measures including wider immunization campaigns, notably among people professionally exposed to the infestation. PMID- 2740783 CU - 91 LI - F TT - Les leptospiroses. EA - A SO - Rev Prat 1989 May 18;39(15):1308-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [35 medline neighbors] UI - 89298157 AU - Baranton G TI - [Classification of spirochetes infecting man] LA - Fre MH - English Abstract MH - Human MH - Leptospira/classification/pathogenicity MH - Phenotype MH - Spirochaetaceae/classification/pathogenicity MH - Spirochaetales/*classification/pathogenicity PT - JOURNAL ARTICLE DA - 890801 DP - 1989 May 18 IS - 0035-2640 TA - Rev Prat PG - 1287-90 CY - FRANCE IP - 15 VI - 39 JC - T1D AA - Author EM - 8910 AB - The systematics od spirochetes must from now own fulfil the genomic criteria recently laid down. Formerly, these parasites were classified on the basis of various phenotypic features, among which the pathogenicity and epidemiological criteria played the predominant role. At present, the order of Spirochaetales is divided into two families: Spirochaetaceae and Leptospiraceae. Two of the four genera of Spirochaetaceae, Treponema and Borrelia, include species that are pathogenic to man. Among Leptospiraceae, only one genus, Leptospira, has pathogenic species. The phenotypic characteristics of the various taxons are detailed, the role of each actor (causative agent, vector, reservoir) in the main pathological complexes and the progress of genotypic studies are briefly described. PMID- 2740779 LI - F TT - Classification des spirochetes infestant l'homme. EA - A SO - Rev Prat 1989 May 18;39(15):1287-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 89332966 AU - Winter AG TI - L hardjo and lambs receiving cow's colostrum [letter; comment] LA - Eng MH - Anemia/etiology/*veterinary MH - Animal MH - Cattle MH - Colostrum/*immunology MH - Leptospira MH - Leptospirosis/*veterinary MH - Sheep MH - Sheep Diseases/*etiology PT - COMMENT PT - LETTER DA - 890828 DP - 1989 May 13 IS - 0042-4900 TA - Vet Rec PG - 520 SB - M CY - ENGLAND IP - 19 VI - 124 JC - XBS EM - 8911 CM - Comment on: Vet Rec 1989 Apr 29;124(17):469 RO - M:LC1 PMID- 2756629 LR - 900101 CU - 91 SO - Vet Rec 1989 May 13;124(19):520 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 89321473 AU - Shalit I AU - Barnea A AU - Shahar A TI - Efficacy of ciprofloxacin against Leptospira interrogans serogroup icterohaemorrhagiae. LA - Eng MH - Animal MH - Ciprofloxacin/*therapeutic use MH - Hamsters MH - Leptospira interrogans/drug effects MH - Mesocricetus MH - Time Factors MH - Weil's Disease/*drug therapy/microbiology RN - 85721-33-1 (Ciprofloxacin) PT - JOURNAL ARTICLE DA - 890825 DP - 1989 May IS - 0066-4804 TA - Antimicrob Agents Chemother PG - 788-9 SB - M CY - UNITED STATES IP - 5 VI - 33 JC - 6HK AA - Author EM - 8910 AB - Ciprofloxacin activity against Leptospira interrogans serogroup icterohaemorrhagiae was studied in vitro and in an animal model. The MBC of ciprofloxacin was 0.6 microgram/ml. Three of three Syrian hamsters died 8 to 9 days after intraperitoneal challenge with 10(6) leptospires. In contrast, five of six animals given ciprofloxacin 3 or 5 days after challenge survived. AD - Tel-Aviv Medical Center, Sackler School of Medicine, Tel-Aviv University, Israel. PMID- 2751290 CU - 90 SO - Antimicrob Agents Chemother 1989 May;33(5):788-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 89205297 AU - Im JG AU - Yeon KM AU - Han MC AU - Kim CW AU - Webb WR AU - Lee JS AU - Han YC AU - Chang WH AU - Chi JG TI - Leptospirosis of the lung: radiographic findings in 58 patients. LA - Eng MH - Adult MH - Animal MH - Female MH - Guinea Pigs MH - Hemorrhage/etiology/*radiography MH - Human MH - Leptospirosis/*radiography MH - Lung Diseases/etiology/*radiography MH - Male MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 890519 DP - 1989 May IS - 0361-803X TA - AJR Am J Roentgenol PG - 955-9 SB - A SB - M SB - X CY - UNITED STATES IP - 5 VI - 152 JC - 3AE AA - Author EM - 8907 AB - Leptospirosis is the disease produced by any of the group of spirochetes of the genus Leptospira. The main organs involved are the liver, central nervous system, kidneys, skeletal muscle, and lungs. Thirty-seven (64%) of 58 patients with leptospirosis, proved by positive serology, had pulmonary radiographic findings. Three radiographic patterns were evident: (1) 21 (57%) of the 37 patients had small nodular densities, (2) six (16%) had large confluent areas of consolidation, and (3) 10 (27%) had diffuse, ill-defined, ground-glass density. Serial radiographs showed a tendency for the nodular pattern to be followed by confluent consolidation and/or ground-glass density. Abnormalities were bilateral, nonlobar in all cases, and had a marked tendency toward peripheral predominance. Pulmonary abnormalities resolved within 15 days, except in eight patients who died because of respiratory failure (six patients) or other causes (two patients). In order to correlate pathology with the radiographic findings, Leptospira, isolated from a patient, was injected intraperitoneally into 20 guinea pigs. All lungs from the guinea pigs showed petecheal hemorrhage, which progressed to large confluent areas of hemorrhage. The typical pulmonary radiographic findings of leptospirosis are compatible with the multifocal pulmonary hemorrhage seen in the guinea pigs. AD - Department of Radiology, College of Medicine, Seoul National University, Korea. PMID- 2705352 SO - AJR Am J Roentgenol 1989 May;152(5):955-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 89384327 AU - Ol'iakova NV AU - Antoniuk VIa TI - [The gray rat (Rattus norvegicus) as a carrier of infectious causative agents in Siberia and the Far East] LA - Rus MH - Animal MH - Carrier State/microbiology/transmission/veterinary MH - Communicable Diseases/microbiology/*transmission/veterinary MH - *Disease Vectors MH - English Abstract MH - Human MH - Rats/*microbiology MH - Rodent Diseases/microbiology/transmission MH - Siberia PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 891017 DP - 1989 May-Jun IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 73-7 CY - USSR IP - 3 JC - M72 AA - Author EM - 8912 AB - Literary data and antiplague institutions' reports demonstrate that Norway rats carry over 24 nosological forms and groups of infectious diseases: plague, tularemia, pseudotuberculosis, intestinal yersiniosis, salmonellosis, erysipeloid, listeriosis, leptospirosis, pasteurellosis, brucellosis, dysentery, paratuberculosis, hemorrhagic nephroso-nephritis, Omsk hemorrhagic fever and Q fever, tick-borne and Japanese encephalitis, lymphocytic choriomeningitis, tick-borne rickettsiosis and rickettsial pox, murine typhus, tsutsugamushi disease and toxoplasmosis. RF - 61 PMID- 2674644 CU - 90 TT - Seraia krysa (Rattus norvegicus) kak nositel' vozbuditelei infektsii v Sibiri i Dal'nem Vostoke. EA - A SO - Med Parazitol (Mosk) 1989 May-Jun;(3):73-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 89317173 AU - Lee HW TI - Hemorrhagic fever with renal syndrome in Korea. LA - Eng MH - Animal MH - *Disease Outbreaks MH - Disease Reservoirs MH - Hemorrhagic Fever with Renal Syndrome/diagnosis/*epidemiology/transmission MH - Human MH - Korea MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 890816 DP - 1989 May-Jun IS - 0162-0886 TA - Rev Infect Dis PG - S864-76 SB - M CY - UNITED STATES VI - 11 Suppl 4 JC - SXN AA - Author EM - 8910 AB - Several clinical variants of hemorrhagic fever with renal syndrome (HFRS) are caused by Hantaan and related viruses. Since 1951, 500-900 patients with HFRS have been hospitalized annually in Korea. Although HFRS is associated primarily with rural areas, it is now being recognized as an urban problem and a particular hazard to laboratory staff using rodents for research. Recently, epidemic outbreaks of leptospirosis and scrub typhus have occurred during the HFRS season, leading to confusion in diagnosis. Serologic diagnosis of HFRS is based on the demonstration of IgM antibodies to Hantaviruses by the indirect fluorescent antibody technique or enzyme-linked immunosorbent assay. The specific Hantavirus causing infection can be identified on the basis of titers of plaque-reduction neutralizing antibody. Results of studies with monoclonal antibodies suggest that viral subtypes exist for each Hantaviral serotype presently recognized. While infection with Hantaviruses is known to be a problem of worldwide dimensions, present evidence indicates that it occurs over a wider area than previously recognized. Vertical transmission of Hantaan virus in a pregnant woman has been documented. AD - World Health Organization Collaborating Centre for Virus Reference and Research, Institute for Viral Diseases, Korea University, Seoul. PMID- 2568676 CU - 94 SO - Rev Infect Dis 1989 May-Jun;11 Suppl 4:S864-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 89254760 AU - Talens LT AU - Beckenhauer WH AU - Thurber ET AU - Cooley AJ AU - Schultz RD TI - Efficacy of viral components of a nonabortigenic combination vaccine for prevention of respiratory and reproductive system diseases in cattle. LA - Eng MH - Animal MH - Antibodies, Viral/biosynthesis MH - Bacterial Vaccines/*standards MH - Bovine Virus Diarrhea-Mucosal Disease/prevention & control MH - Campylobacter fetus/immunology MH - Cattle MH - Cattle Diseases/*prevention & control MH - Diarrhea Virus, Bovine Viral/immunology MH - Female MH - Genital Diseases, Female/prevention & control/*veterinary MH - Herpesvirus 1, Bovine/immunology MH - Infectious Bovine Rhinotracheitis/prevention & control MH - Leptospira/immunology MH - Male MH - Parainfluenza Virus 3, Human/immunology MH - Paramyxoviridae Infections/prevention & control/veterinary MH - Paramyxovirus Infections/prevention & control/veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/prevention & control/veterinary MH - Respiratory Syncytial Viruses/immunology MH - Respiratory Tract Infections/prevention & control/*veterinary MH - Viral Vaccines/*standards RN - 0 (Antibodies, Viral) RN - 0 (Bacterial Vaccines) RN - 0 (Viral Vaccines) PT - JOURNAL ARTICLE DA - 890628 DP - 1989 May 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1273-80 SB - M CY - UNITED STATES IP - 9 VI - 194 JC - HAV AA - Author EM - 8909 AB - Efficacy and safety of components of an IM-administered vaccine for prevention of infectious bovine rhinotracheitis virus (IBRV), parainfluenza type-3 (PI-3) virus, bovine viral diarrhea virus (BVDV), and respiratory syncytial virus (RSV) infections and campylobacteriosis and leptospirosis were evaluated in cattle, including calves and pregnant cows. Challenge of immunity tests were conducted in calves for IBRV, PI-3 virus, or BVDV vaccinal components. All inoculated calves developed serum-neutralizing antibodies and had substantially greater protection (as measured by clinical rating systems) than did controls after challenge exposure to virulent strains of IBRV, PI-3 virus, BVDV, or RSV. In in utero tests, IBRV or bovine RSV vaccinal strains were inoculated into fetuses of pregnant cows. Histologic changes or abortions did not occur after fetal inoculation of the RSV vaccinal strain, and 10 of 14 fetuses responded serologically. Of 9 fetuses, one responded serologically to the IBRV vaccinal strain after in utero inoculation and was aborted 3 weeks later. In an immunologic interference test, 10 calves vaccinated with 2 doses of the multivalent vaccine, containing the 4 viral components and a Campylobacter- Leptospira bacterin, developed serum-neutralizing antibodies to IBRV, PI-3 virus, BVDV, and RSV without evidence of serologic interference. Under field conditions, 10,771 cattle, including 4,543 pregnant cows, were vaccinated. Vaccine-related abortions did not occur. AD - Biological Research and Development Division, Norden Laboratories, Lincoln, NE 68501. PMID- 2542202 CU - 96 SO - J Am Vet Med Assoc 1989 May 1;194(9):1273-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 91299953 AU - Grau A AU - Bofill D AU - Gine J AU - Manresa JM AU - Bonaventura I TI - [Leptospirosis: is it really very infrequent? (letter)] LA - Spa MH - Human MH - Leptospirosis/*diagnosis/epidemiology PT - LETTER DA - 910822 DP - 1989 May IS - 0213-005X TA - Enferm Infecc Microbiol Clin PG - 292 CY - SPAIN IP - 5 VI - 7 JC - A10 EM - 9110 PMID- 2490738 TT - Leptospirosis: es realmente muy infrecuente? SO - Enferm Infecc Microbiol Clin 1989 May;7(5):292 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 90211753 AU - Guasticchi G TI - [Verification of antibiotic treatment after animal bites among patients at the antirabies center in Rome] LA - Ita MH - Adolescence MH - Adult MH - Aged MH - Aged, 80 and over MH - Animal MH - Antibiotics/*therapeutic use MH - Bites and Stings/*drug therapy MH - Child MH - Child, Preschool MH - Community Health Centers MH - English Abstract MH - Human MH - Middle Age MH - Rome MH - Wound Infection/etiology/*prevention & control RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 900516 DP - 1989 May-Aug IS - 1120-9135 TA - Ann Ig PG - 621-7 CY - ITALY IP - 3-4 VI - 1 JC - AND AA - Author EM - 9007 AB - The study aimed at searching whether antibiotic prophylaxis was practised after animal bites, and, in this case, what were the criteria adopted. It was performed by considering 162 outpatients requiring assistance after animal bites at the Antirabies Centre of Rome, Italy. In this circumstances, prevention of bacterial and viral infections is performed by wound detersion, by administering anti-tetanus and anti- rabid prophylaxis where required by italian policy, according to the patient's history. Infectious complications are described in literature as a common consequence of animal bites and include cellulitis, septic arthritis, osteomyelitis and even fatal sepsis. Microorganisms related to these infections are frequently typical of animal oral flora and include aerobic and anaerobic species, such as Pasteurella multocida, DF-2, and Leptospira. It was noted that 58 (35.8%) out of 162 were treated with antibiotic prophylaxis; the most common drug used was amoxicillin, given in 18 cases (31%). The overall results do not show any particular reason for practising or not this prophylaxis. The need of standardising the behaviour of Emergency Services, where a different and unjustified attitude to treat or not patients with antibiotic prophylaxis in order to prevent infectious complications following animal bites was observed, emerges from this study. PMID- 2483634 CU - 95 TT - Verifica del trattamento antibiotico conseguente a morsicatura di animale tra i pazienti del centro antirabbico di Roma. EA - A SO - Ann Ig 1989 May-Aug;1(3-4):621-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 89268371 AU - Simpson VR AU - Done SH TI - L hardjo and lambs receiving cows' colostrum [letter] [see comments] LA - Eng MH - Anemia/immunology/*veterinary MH - Animal MH - Animals, Newborn/immunology MH - Antibodies, Bacterial/*analysis MH - Cattle/immunology MH - *Colostrum MH - Female MH - Leptospira/*immunology MH - Sheep MH - Sheep Diseases/*immunology MH - Syndrome/veterinary RN - 0 (Antibodies, Bacterial) PT - LETTER DA - 890711 DP - 1989 Apr 29 IS - 0042-4900 TA - Vet Rec PG - 469 SB - M CY - ENGLAND IP - 17 VI - 124 JC - XBS EM - 8909 CM - Comment in: Vet Rec 1989 May 13;124(19):520 RO - M:LC1 PMID- 2728303 LR - 900101 CU - 91 SO - Vet Rec 1989 Apr 29;124(17):469 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 90048319 AU - Domnisoru L AU - Chiriac E TI - [Acute carbon tetrachloride poisoning] LA - Rum MH - Accidents, Occupational MH - Acute Disease MH - Adult MH - Aged MH - Carbon Tetrachloride Poisoning/complications/*diagnosis MH - Case Report MH - English Abstract MH - Female MH - Human MH - Male MH - Middle Age MH - Occupational Diseases/chemically induced/complications/diagnosis MH - Romania PT - JOURNAL ARTICLE DA - 891129 DP - 1989 Apr-Jun IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 389-90 CY - ROMANIA IP - 2 VI - 93 JC - SHP AA - Author EM - 9002 AB - The authors investigate 20 cases of acute carbon tetrachloride (CCl4) poisoning representing 50% of all acute poisonings with organo-chlorate solvents admitted during a 5-year interval to Galati District Hospital. All our CCl4 acute poisoning cases were accidental, mild and moderate in form, and prevailed in man (80%). Depending on the ingested (more seldom) or inhaled amounts, CCl4 induces neurological and or digestive disturbances, parenchymatous involvements, prevalently hepatic (misdiagnosis of acute viral hepatitis and leptospirosis) or mixed, hepatorenal. Characteristic to the mixed form is the staged evolution of the clinico-biological manifestations, acute toxic hepatitis in the first week and acute toxic tubulo-interstitial nephropathy in the second one, both requiring proper management. Five selected cases are presented. PMID- 2814060 TT - Intoxicatia acuta cu tetraclorura de carbon. EA - A SO - Rev Med Chir Soc Med Nat Iasi 1989 Apr-Jun;93(2):389-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 90048302 AU - Oana C AU - Teodorescu E AU - Grigore L AU - Birzu N AU - Baciu F AU - Davideanu M TI - [The epidemiology and prevention of leptospirosis in Iasi County] LA - Rum MH - Age Factors MH - Human MH - Leptospirosis/*epidemiology/prevention & control MH - Occupations MH - Romania/epidemiology MH - Sex Factors MH - Weil's Disease/epidemiology/prevention & control PT - JOURNAL ARTICLE DA - 891129 DP - 1989 Apr-Jun IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 315-7 CY - ROMANIA IP - 2 VI - 93 JC - SHP EM - 9002 PMID- 2814047 TT - Unele consideratii asupra epidemiologiei si profilaxiei leptospirozelor in judetul Iasi. SO - Rev Med Chir Soc Med Nat Iasi 1989 Apr-Jun;93(2):315-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 90021478 AU - Zhang FZ AU - Zhou CY AU - Wang XY TI - [A new leptospiral serovar in the autumnalis serogroup] LA - Chi MH - English Abstract MH - Human MH - Leptospira interrogans/*classification/isolation & purification MH - Nomenclature MH - Serotyping MH - Weil's Disease/microbiology PT - JOURNAL ARTICLE DA - 891106 DP - 1989 Apr IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 141-4 CY - CHINA IP - 2 VI - 29 JC - XNA AA - Author EM - 9001 AB - Strain A6 of leptospire was isolated from blood culture of a case with leptospirosis on July 1, 1962 in Mengla county, Xishuangbanna, Yunnan. It is proved a new serovar belonging to serogroup Autumnalis by cross agglutination and cross agglutinin-absorption tests. The name, Leprospira interrogans serovar nanla with reference strain A6 is proposed. PMID- 2800544 EA - A SO - Wei Sheng Wu Hsueh Pao 1989 Apr;29(2):141-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 89333051 AU - Nazarchuk LV AU - Mel'nitskaia EV TI - [Antileptospiral antibodies in the blood serum of donors] LA - Rus MH - Antibodies, Bacterial/*analysis MH - ABO Blood-Group System/immunology MH - *Blood Donors MH - English Abstract MH - Hemagglutination Tests MH - Human MH - Leptospira/*immunology MH - Reference Values RN - 0 (Antibodies, Bacterial) RN - 0 (ABO Blood-Group System) PT - JOURNAL ARTICLE DA - 890831 DP - 1989 Apr IS - 0049-6804 TA - Vrach Delo PG - 108-9 CY - USSR IP - 4 JC - XLS AA - Author EM - 8911 AB - The authors investigated the content of antileptospiral antibodies in 930 blood sera of nonimmunized blood donors. It was established that high titers of antileptospiral antibodies are contained in 5.2% of practically healthy persons. PMID- 2756667 CU - 91 TT - Antileptospiroznye antitela v syvorotke krovi donorov. EA - A SO - Vrach Delo 1989 Apr;(4):108-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 89262739 AU - Carco FP AU - Saliva G AU - Guazzotti G AU - Gobber M AU - Gili C TI - [Recent clinical findings in leptospirosis] LA - Ita MH - Diagnosis, Differential MH - Electrocardiography MH - English Abstract MH - Human MH - Leptospirosis/complications/*diagnosis/physiopathology MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 890713 DP - 1989 Apr IS - 0026-4806 TA - Minerva Med PG - 377-80 SB - M SB - X CY - ITALY IP - 4 VI - 80 JC - N6M AA - Author EM - 8909 AB - Forty-four patients admitted 1978-1986 were examined which suffered from leptospirosis. The authors bring a new contribution on the clinic of leptospirosis. They confirm that leptospirosis often assumes a polymorphic clinical degree. They stress the importance of an early diagnosis. AD - U.S.S.L. n. 45, Ospedale S. Andrea, Vercelli, Divisione di Malattie Infettive. PMID- 2725940 TT - Ulteriori acquisizioni cliniche sulla leptospirosi. EA - A SO - Minerva Med 1989 Apr;80(4):377-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 89234631 AU - Davenport A AU - Rugman FP AU - Desmond MJ AU - Ganta R TI - Is thrombocytopenia seen in patients with leptospirosis immunologically mediated? LA - Eng MH - Case Report MH - Human MH - Leptospirosis/*immunology MH - Male MH - Middle Age MH - Platelet Count MH - Thrombocytopenia/*immunology PT - JOURNAL ARTICLE DA - 890620 DP - 1989 Apr IS - 0021-9746 TA - J Clin Pathol PG - 439-40 SB - A SB - M SB - X CY - ENGLAND IP - 4 VI - 42 JC - HT3 EM - 8908 PMID- 2715354 SO - J Clin Pathol 1989 Apr;42(4):439-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [9 protein links] [1 nucleotide link] [205 medline neighbors] UI - 89197778 AU - Yelton DB AU - Peng SL TI - Identification and nucleotide sequence of the Leptospira biflexa serovar patoc trpE and trpG genes. LA - Eng MH - Amino Acid Sequence MH - Anthranilate Synthase/genetics MH - Base Sequence MH - Codon MH - Comparative Study MH - *Genes, Bacterial MH - Genetic Complementation Test MH - Leptospira/*genetics MH - Molecular Sequence Data MH - Peptide Chain Initiation MH - Restriction Mapping MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Tryptophan RN - EC 4.1.3.27 (Anthranilate Synthase) RN - 0 (Codon) RN - 6912-86-3 (Tryptophan) PT - JOURNAL ARTICLE ID - 5 SO7-RR05433/RR/NCRR ID - 2 R01 DE04645/DE/NIDR DA - 890512 DP - 1989 Apr IS - 0021-9193 TA - J Bacteriol PG - 2083-9 SB - M CY - UNITED STATES IP - 4 VI - 171 JC - HH3 AA - Author EM - 8907 AB - Leptospira biflexa is a representative of an evolutionarily distinct group of eubacteria. In order to better understand the genetic organization and gene regulatory mechanisms of this species, we have chosen to study the genes required for tryptophan biosynthesis in this bacterium. The nucleotide sequence of the region of the L. biflexa serovar patoc chromosome encoding the trpE and trpG genes has been determined. Four open reading frames (ORFs) were identified in this region, but only three ORFs were translated into proteins when the cloned genes were introduced into Escherichia coli. Analysis of the predicted amino acid sequences of the proteins encoded by the ORFs allowed us to identify the trpE and trpG genes of L. biflexa. Enzyme assays confirmed the identity of these two ORFs. Anthranilate synthase from L. biflexa was found to be subject to feedback inhibition by tryptophan. Codon usage analysis showed that there was a bias in L. biflexa towards the use of codons rich in A and T, as would be expected from its G + C content of 37%. Comparison of the amino acid sequences of the trpE gene product and the trpG gene product with corresponding gene products from other bacteria showed regions of highly conserved sequence. AD - Department of Microbiology and Immunology, West Virginia University, Morgantown 26506. PMID- 2703466 CU - 96 SI - GENBANK/M22468 SO - J Bacteriol 1989 Apr;171(4):2083-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 89363162 AU - Kantha SS TI - Hideyo Noguchi's research on yellow fever (1918-1928) in the pre- electron microscopic era. LA - Eng MH - Africa, Western MH - Central America MH - History of Medicine, 20th Cent. MH - Human MH - South America MH - Yellow Fever/etiology/*history/microbiology PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 890925 DP - 1989 Apr IS - 0023-1924 TA - Kitasato Arch Exp Med PG - 1-9 CY - JAPAN IP - 1 VI - 62 JC - KVS AA - Author EM - 8912 AB - One of the low points in Hideyo Noguchi's career as a pioneer medical microbiologist was his investigations on yellow fever between 1918 and 1924 in Central and South America. His discovery that spirochete Leptospira icteroides was the causative pathogen of yellow fever was discredited in 1927. This paper evaluates the situation under which Noguchi conducted his experiments and assesses the causes which might have resulted in his erroneous interpretation in the pre-electron microscopic era. Even 60 years after Noguchi's untimely death, much remains to be known about the virulence of pathogenic strains of yellow fever. PMID- 2671469 CU - 90 SO - Kitasato Arch Exp Med 1989 Apr;62(1):1-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 91175947 AU - Kirkbride CA AU - Johnson MW TI - Serologic examination of aborted ovine and bovine fetal fluids for the diagnosis of border disease, bluetongue, bovine viral diarrhea, and leptospiral infections. LA - Eng MH - Abortion, Veterinary/*diagnosis MH - Agglutination Tests MH - Amniotic Fluid/immunology MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/analysis MH - Bluetongue/diagnosis MH - Border Disease/diagnosis MH - Bovine Virus Diarrhea-Mucosal Disease/diagnosis MH - Cattle MH - Cattle Diseases/*diagnosis MH - Female MH - Fluorescent Antibody Technique MH - Leptospirosis/diagnosis/veterinary MH - Neutralization Tests MH - Pregnancy MH - Sheep MH - Sheep Diseases/*diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 910501 DP - 1989 Apr IS - 1040-6387 TA - J Vet Diagn Invest PG - 132-8 SB - M CY - UNITED STATES IP - 2 VI - 1 JC - A2D AA - Author EM - 9107 AB - Fetal serum from most of 994 bovine and 553 ovine aborted fetuses was tested serologically for antibodies to border disease (BD), bovine viral diarrhea (BVD), and bluetongue (BT) viruses, and to Leptospira sp., and the results were compared with the results of isolation procedures, fluorescent antibody tests (FAT), and histologic examinations of the same fetuses. Antibodies to BT virus were not found in any of the 994 bovine and 553 ovine fetuses. Antibody titers to BVD virus were present in 39 of 966 bovine fetuses tested, and BVD virus was detected in 4 of the 39. Four of 74 fetuses in which the BVD virus was detected by FAT or isolation had titers to BVD virus. Microagglutination (MAT) titers to 1 or more of 5 serovars of leptospires were present in 52 of 773 bovine fetal sera tested. Leptospires were not detected by FAT in any bovine fetuses that had leptospiral antibody titers. Leptospires were detected by FAT in 15 aborted calves, and none of these had MAT titers. Antibody titers to BD virus were present in 80 of 486 fetal lamb sera tested, and the virus was detected by FAT or isolation in 3 of the 80 fetuses. Border disease virus was detected in 14 of 486 fetal lambs tested. Twelve of the 14 were tested serologically and 3 had titers to BD virus. Leptospiral antibody titers were present in 27 of 326 ovine fetal sera tested. Leptospires were not detected in any of the 326 ovine fetuses tested by FAT. AD - Veterinary Science Department, South Dakota State University, Brookings 57007. PMID- 2562192 CU - 93 SO - J Vet Diagn Invest 1989 Apr;1(2):132-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 91175952 AU - Nielsen JN AU - Armstrong CH AU - Turek JJ AU - Nielsen NC TI - Etiologic studies on late-term swine abortions. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Female MH - Fetal Death/microbiology/*veterinary MH - Fluorescent Antibody Technique MH - Microscopy, Electron MH - Pregnancy MH - Spirochaetales/*isolation & purification/ultrastructure MH - Spirochaetales Infections/microbiology/*veterinary MH - Spiroplasma/isolation & purification/ultrastructure MH - Support, U.S. Gov't, Non-P.H.S. MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 910501 DP - 1989 Apr IS - 1040-6387 TA - J Vet Diagn Invest PG - 160-4 SB - M CY - UNITED STATES IP - 2 VI - 1 JC - A2D AA - Author EM - 9107 AB - One hundred thirty-eight swine abortions were studied in detail in an effort to identify an etiologic agent. A viral agent was implicated in 7 cases. Bacteria were isolated in less than half of the examined cases: however, in 61% of the cases, motile, filamentous organisms were observed in tissues and fluids. Although swine sera from farms experiencing reproductive problems had a high reactor rate to Leptospira bratislava antigen, electron microscopy of the observed organism revealed a wall-free prokaryote morphologically typical of the class Mollicutes. AD - Indiana Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907. PMID- 2488334 SO - J Vet Diagn Invest 1989 Apr;1(2):160-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 91175949 AU - Miller DA AU - Wilson MA AU - Kirkbride CA TI - Evaluation of multivalent Leptospira fluorescent antibody conjugates for general diagnostic use. LA - Eng MH - Animal MH - Antibodies, Bacterial/*diagnostic use MH - Cattle MH - Cattle Diseases/diagnosis MH - *Fluorescent Antibody Technique MH - Hamsters MH - Kidney/microbiology MH - Leptospira/*immunology/isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - Predictive Value of Tests MH - Sheep MH - Sheep Diseases/diagnosis MH - Swine MH - Swine Diseases/diagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 910501 DP - 1989 Apr IS - 1040-6387 TA - J Vet Diagn Invest PG - 146-9 SB - M CY - UNITED STATES IP - 2 VI - 1 JC - A2D AA - Author EM - 9107 AB - Four lots of conjugate were evaluated for optimal dilution and degree of fluorescence produced with reference cultures and bovine and porcine leptospira isolates. One lot that uniformly produced better fluorescence was evaluated for sensitivity and specificity with reference cultures, isolates, culture-positive tissues, and 13 other bacterial species. Further evaluation of the conjugates was done with bovine, porcine, and ovine specimens submitted to a diagnostic laboratory. Leptospires were detected with the fluorescent antibody test (FAT) in 9 of 21 culture-positive bovine kidneys and were detected in diluted cultures when present at concentrations of 10(2)-10(3) organisms/ml. With the exception of Treponema hyodysenteriae, FAT's of other bacterial cultures produced minimal fluorescence or were negative. Positives were characterized by moderate to brilliant fluorescence of typical cell forms, and most nonspecific fluorescence was eliminated with a flazo-orange counterstain. The results indicated that the FAT utilizing multivalent conjugates could be used successfully as an additional method for diagnosis of leptospira infections. AD - National Veterinary Services Laboratories, US Department of Agriculture, Ames, IA 50010. PMID- 2488332 CU - 91 SO - J Vet Diagn Invest 1989 Apr;1(2):146-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 91175946 AU - Hedstrom O AU - Sonn R AU - Dearing P AU - Snyder SP AU - Lassen ED TI - Measurement of IgG concentration in ovine fetal fluids: a useful diagnostic test. LA - Eng MH - Abortion, Veterinary/*diagnosis MH - Amniotic Fluid/*immunology MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Protozoan/analysis MH - Campylobacter/immunology MH - Campylobacter Infections/diagnosis MH - Chlamydia psittaci/immunology MH - Chlamydia Infections/diagnosis MH - Female MH - IgG/*analysis MH - Leptospira/immunology MH - Pregnancy MH - Sheep MH - Sheep Diseases/*diagnosis MH - Toxoplasma/immunology MH - Toxoplasmosis, Animal/diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Protozoan) PT - JOURNAL ARTICLE DA - 910501 DP - 1989 Apr IS - 1040-6387 TA - J Vet Diagn Invest PG - 128-31 SB - M CY - UNITED STATES IP - 2 VI - 1 JC - A2D AA - Author EM - 9107 AB - The Veterinary Diagnostic Laboratory at Oregon State University received 172 aborted ovine fetuses during the 1985-1987 lambing seasons; from 120 of these, body fluids were evaluated for IgG levels. Fifty-two (43%) of the fetal fluids had immunoglobulin G (IgG) levels greater than 15 mg/dl. Forty-five (87%) of the fluids with elevated IgG levels were confirmed or presumed toxoplasma or chlamydia abortions. A mean fetal fluid IgG concentration of 111.5 +/- 78 mg/dl was found for the 26 toxoplasma abortions; for the 19 chlamydia abortions, a mean IgG concentration of 109 +/- 91 mg/dl was found. Antibody titers equal to or greater than 1:40 against Toxoplasma gondii were detected in 23 fetal fluids. Fetal fluid IgG concentration less than 15 mg/dl was found to be associated with bacterial organisms (i.e., Campylobacter sp.) as the confirmed or presumed cause of abortion. These results suggest that measurement of fetal fluid IgG concentration is a useful, supportive diagnostic test in determining the cause of ovine abortion, and should be included as a routine laboratory procedure for ovine abortion diagnosis. AD - Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Oregon State University, Corvallis 97331-4802. PMID- 2488331 CU - 91 SO - J Vet Diagn Invest 1989 Apr;1(2):128-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [1 nucleotide link] [202 medline neighbors] UI - 89183618 AU - Fukunaga M AU - Horie I AU - Mifuchi I TI - Nucleotide sequence of a 23S ribosomal RNA gene from Leptospira interrogans serovar canicola strain Moulton. LA - Eng MH - Base Sequence MH - *Genes, Bacterial MH - Leptospira interrogans/*genetics MH - Molecular Sequence Data MH - RNA, Bacterial/*genetics MH - RNA, Ribosomal/*genetics MH - RNA, Ribosomal, 23S/*genetics RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal) RN - 0 (RNA, Ribosomal, 23S) PT - JOURNAL ARTICLE DA - 890509 DP - 1989 Mar 11 IS - 0305-1048 TA - Nucleic Acids Res PG - 2123 SB - M SB - X CY - ENGLAND IP - 5 VI - 17 JC - O8L EM - 8907 AD - Faculty of Pharmacy and Pharmaceutical Science, Fukuyama University, Hiroshima, Japan. PMID- 2467256 CU - 95 SI - GENBANK/X14249 SO - Nucleic Acids Res 1989 Mar 11;17(5):2123 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 90007463 AU - Xiao JG AU - Dai BM TI - [Purification and SDS-page analysis of axial filaments from leptospires] LA - Chi MH - Animal MH - Comparative Study MH - Cytoskeletal Proteins/*isolation & purification MH - Electrophoresis, Polyacrylamide Gel/methods MH - English Abstract MH - Leptospira/*analysis/ultrastructure MH - Leptospira interrogans/analysis/ultrastructure MH - Support, Non-U.S. Gov't RN - 0 (Cytoskeletal Proteins) PT - JOURNAL ARTICLE DA - 891115 DP - 1989 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 1-4 CY - CHINA IP - 1 VI - 20 JC - GEB AA - Author EM - 9001 AB - A modified method, differential centrifugation followed by sucrose density centrifugation, was used to purify axial filaments from three strains of Leptospires. Ultrastructure of the axial filaments was studied and profiles of the axial filaments were characterized and compared. The results have shown that all the three strains of Leptospires, i.e., L. interrogsans serovar Lai strain 017, L. biflexa serovar patoc strain Patoc I and L. illini strain 3055, have two axial filaments in one cell. The axial filament is 20 nm in diameter. It is the first observation that the end which inserts the cytoplasms cylinder is wider in diameter than the free one. An insertion pore structure is observed. The new method yields 1.5mg axial filaments from 12 g leptospires cells. SDS-PAGE was first employed in the analysis of axial filaments of leptospires. The results have also shown that there are 6 proteins in the axial filaments of strain 017, MW 26,000-50,000 while 7 proteins in the axial filaments of strain Patoc I and strain 3055. MW 29,000-80,000 and 28,500-80,000 respectively. Interestingly, all the axial filaments of the three strains have a common protein band of MW 31,500. The possibility of using axial filament proteins as a new criterion for typing and a serodiagnosis antigen is discussed. PMID- 2793131 CU - 92 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1989 Mar;20(1):1-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 89265485 AU - Philipp R AU - Waitkins S AU - Caul O AU - Roome A AU - McMahon S AU - Enticott R TI - Leptospiral and hepatitis A antibodies amongst windsurfers and waterskiers in Bristol City Docks. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Antibodies, Bacterial/*analysis MH - Child MH - Cross-Sectional Studies MH - England MH - Female MH - Health Education MH - Hepatitis A/*immunology MH - Hepatitis Antibodies/*analysis MH - Human MH - *Immersion MH - Leptospira interrogans/*immunology MH - Male MH - Middle Age MH - *Sports MH - Water Microbiology RN - 0 (Antibodies, Bacterial) RN - 0 (Hepatitis Antibodies) PT - JOURNAL ARTICLE DA - 890707 DP - 1989 Mar IS - 0033-3506 TA - Public Health PG - 123-9 CY - ENGLAND IP - 2 VI - 103 JC - QI7 AA - Author EM - 8909 AB - Previous epidemiological studies have detected a substantial risk of gastroenteritis associated with snorkel swimming events in the Bristol City Docks. The event has since been discontinued. Similar risks were not identified at that time for surface-based events. A subsequent fatality from Weil's disease (Leptospirosis) and a case of Hepatitis A associated with surface water immersion in the Bristol City Docks water prompted this study of Leptospiral and Hepatitis A immunity amongst regular windsurfers and waterskiers. Although one person showed evidence of past Leptospiral infection and several people showed evidence of previous Hepatitis A, a causal association with Docks water exposure was not established. Nevertheless, there was sufficient public concern to justify the introduction of precautions against the potential health risks associated with immersion in the City Docks. The study findings and these preventive measures are described. PMID- 2786228 CU - 91 SO - Public Health 1989 Mar;103(2):123-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 89301219 AU - Krivulis DB AU - Groshev AN AU - Tsimermane GI AU - Daugulis EK AU - Sondore AA TI - [Treatment of terminal forms of icterohemorrhagic leptospirosis] LA - Rus MH - English Abstract MH - Hemoperfusion MH - Human MH - Resuscitation MH - Weil's Disease/*therapy PT - JOURNAL ARTICLE DA - 890804 DP - 1989 Mar-Apr IS - 0201-7563 TA - Anesteziol Reanimatol PG - 59-62 CY - USSR IP - 2 JC - 4ST AA - Author EM - 8910 AB - Complex therapy, using hemosorption in combination with hemodialysis and hyperbaric oxygenation, was suggested for the treatment of patients with terminal stages of icterohemorrhagic leptospirosis. Such complex therapy decreased the mortality rate of patients with terminal stages of icterohemorrhagic leptospirosis from 76-96% to 18-22% and reduced the in-hospital stay from 60-80 to 35-40 days. PMID- 2742193 TT - Lechenie terminal'nykh form ikterogemorragicheskogo leptospiroza. EA - A SO - Anesteziol Reanimatol 1989 Mar-Apr;(2):59-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 89268638 AU - Nicholson GD AU - Edwards CN AU - Hassell TA AU - Everard CO AU - Callender J TI - Urinary diagnostic indices in the management of leptospirosis. Selection of patients for dialysis therapy [published erratum appears in West Indian Med J 1989 Jun;38(2):87] LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Female MH - Human MH - Kidney Failure, Acute/etiology/therapy/*urine MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Peritoneal Dialysis MH - Support, Non-U.S. Gov't MH - Uremia/etiology/therapy/*urine PT - JOURNAL ARTICLE DA - 890703 DP - 1989 Mar IS - 0043-3144 TA - West Indian Med J PG - 33-8 CY - JAMAICA IP - 1 VI - 38 JC - XN4 AA - Author EM - 8909 AB - Cases of leptospirosis admitted to the Queen Elizabeth Hospital (QEH), Barbados, were assessed for the presence of "pre-renal azotaemia" (NON- ARF) as opposed to "acute renal failure" (ARF). Distinction between the two diagnoses was made on the basis of clinical course. Peritoneal dialysis was inappropriately utilised in 26% of patients receiving such therapy. This study evaluates diagnostic tests for pre-renal azotaemia, and acute renal failure in leptospirosis, and indicates guidelines for the management of azotaemia in such patients. U/P urea and osmolar ratios show high sensitivity and specificity in diagnosing pre-renal azotaemia. While "early" dialysis is essential for patients with acute leptospiral renal failure, in those with plasma creatinines less than 600 mumol/litre on entry and indices indicating NON-ARF, decisions regarding dialysis can safely be delayed for 48-72 hours while the effect of rehydration is assessed. RO - M:MWS PMID- 2728431 LR - 890919 SO - West Indian Med J 1989 Mar;38(1):33-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 89234523 AU - LeFebvre RB AU - Perng GC TI - Genetic and antigenic characterization of Borrelia coriaceae, putative agent of epizootic bovine abortion. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Antigens, Bacterial/*analysis MH - Autoradiography MH - Blotting, Southern MH - Blotting, Western MH - Borrelia/*genetics/immunology MH - Cattle MH - Cattle Diseases/*microbiology MH - Deoxyribonuclease HindIII MH - DNA, Bacterial/*analysis MH - Electrophoresis, Agar Gel MH - Electrophoresis, Polyacrylamide Gel MH - Female MH - Human MH - Nucleic Acid Hybridization MH - Plasmids MH - Pregnancy MH - Restriction Mapping RN - EC 3.1.21.- (Deoxyribonuclease HindIII) RN - 0 (Antigens, Bacterial) RN - 0 (DNA, Bacterial) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 890622 DP - 1989 Mar IS - 0095-1137 TA - J Clin Microbiol PG - 389-93 SB - M CY - UNITED STATES IP - 3 VI - 27 JC - HSH AA - Author EM - 8908 AB - Borrelia coriaceae was characterized genetically and antigenically by utilizing the following techniques: restriction endonuclease analysis, Southern blotting and genomic hybridization, pulsed-field electrophoresis, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and immunoblotting. The B. coriaceae genome revealed unique and characteristic banding patterns both by agarose gel electrophoresis and by hybridization when compared with several Borrelia burgdorferi isolates. Pulsed-field gel electrophoresis demonstrated several linear plasmids ranging from 65 to 30 kilobase pairs. Cross-reaction with B. burgdorferi antigens ranging from 21 to 26 kilodaltons were demonstrated by immunoblotting with rabbit anti-B. coriaceae antiserum. However, most B. coriaceae antigens were quite distinct when compared with B. burgdorferi and Leptospira interrogans antigens. AD - Department of Veterinary Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis 95616. PMID- 2715314 CU - 92 SO - J Clin Microbiol 1989 Mar;27(3):389-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 89167896 AU - Johnson LW TI - Llama reproduction. LA - Eng MH - Animal MH - Artiodactyla/*physiology MH - *Breeding MH - Camelids, New World/anatomy & histology/*physiology MH - Embryo Transfer/veterinary MH - Female MH - Genitalia, Female/abnormalities MH - Infertility/diagnosis/prevention & control/veterinary MH - Insemination, Artificial/veterinary MH - Male MH - Pregnancy MH - Pregnancy Complications/veterinary MH - Pregnancy, Animal/*physiology MH - *Reproduction PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 890511 DP - 1989 Mar IS - 0749-0720 TA - Vet Clin North Am Food Anim Pract PG - 159-82 SB - M CY - UNITED STATES IP - 1 VI - 5 JC - CFP AA - Author EM - 8907 AB - The reproductive anatomy, physiology, and breeding behavior of the llama is unique enough to make familiarity with it imperative. Female puberty averages 12 months, while many males are not reproductively functional until after 3 years. Proper management of a breeding pair or herd is necessary to maintain maximum reproductive performance. Proof of pregnancy is suggested by rejection of the male and may/should be confirmed by progesterone assay, rectal palpation, or ultrasound techniques. The postpartum female is notable for breeding back rapidly, with high pregnancy rates resulting. Both male and female factors enter into llama infertility, with each gender having significant incidence of reproductive anatomical abnormalities. Management as well as acquired infertility problems (heat factors, trauma, infection, neoplasia, and hormonal imbalances) contribute to the bulk of infertility cases investigated. Techniques used to diagnose infertility in llamas are quite comparable to the equine species; however, female body size and semen analysis in the male present significant challenges. The approach to therapy has been quite empirical to date, owing to lack of consistent problems and numbers to afford conclusive trials. Alterations of pregnancy include resorption, abortions, and stillbirths. Resorption between 30 to 60 days of gestation is reported regularly. Abortions caused by stress occur regularly. Infection abortions caused by leptospirosis, toxoplasmosis, and chlamydiosis are to be expected. Ponderosa pine-related abortions are suspected. In summary, I find use for a broad background in large animal theriogenology to apply to llama infertility. There no doubt are additional diagnostic techniques and therapeutic regimens that have application, and it is up to us all to keep good records and share the information. AD - College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins. RF - 20 PMID- 2647232 CU - 90 SO - Vet Clin North Am Food Anim Pract 1989 Mar;5(1):159-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 90100326 AU - Nicodemo AC AU - Medeiros N AU - del Negro G AU - Amato Neto V TI - [Hematologic changes in leptospirosis] LA - Por MH - Adolescence MH - Adult MH - Aged MH - Blood Cell Count MH - Bone Marrow/cytology MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*blood MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 900205 DP - 1989 Mar-Apr IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 71-9 CY - BRAZIL IP - 2 VI - 31 JC - S9D AA - Author EM - 9004 AB - 30 cases of leptospirosis admitted to the Clinica de Doencas Infecciosas e Parasitarias do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo were studied for blood count alterations. 16 patients (53.3%) had a normal white blood cell count at the moment of admission. 12 patients (40%) presented a high white blood cell count and 2 (6.6%) had a low count. 29 patients (96.6%) had a high proportion of neutrophils and 25 patients (83.3%) presented a high number of immature forms. 24 patients had anemia. Thrombocytopenia was present in 26 patients (86.6%). The most characteristic changes found in bone marrow aspirate were the alterations of M:E ratio (myeloid- erythroid ratio) due to relative and/or absolute hyperplasia of the myeloid series, and/or relative and/or absolute hypoplasia of the erythroid series; erythropoiesis was predominantly micro-erythroblastic in many patients; mild to moderate plasmocytosis was found; and, regarding the interstitial series, increased macrophagic activity was noted. There was no direct correlation between the number of megakaryocytes and the blood platelet count, but there was a direct correlation between the bone marrow platelet production and blood platelet count. We believe that it is very difficult to have a good idea of the dynamic mechanisms that lead to medullar platelet production in the presence of platelet consumption, through a random test of the bone marrow. PMID- 2602804 TT - Alteracoes hematologicas na leptospirose. EA - A SO - Rev Inst Med Trop Sao Paulo 1989 Mar-Apr;31(2):71-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 90117599 AU - Wong TW AU - Chan YC AU - Joo YG AU - Lee HW AU - Lee PW AU - Yanagihara R TI - Hantavirus infections in humans and commensal rodents in Singapore. LA - Eng MH - Adult MH - Animal MH - Antibodies, Viral/*blood MH - Female MH - Fluorescent Antibody Technique MH - Hantavirus/*immunology/isolation & purification MH - Hemorrhagic Fever with Renal Syndrome/*epidemiology/veterinary MH - Human MH - Insectivora/immunology MH - Lung/microbiology MH - Male MH - Mice/immunology MH - Muridae/immunology MH - Rats/immunology/microbiology MH - Rodent Diseases/*epidemiology MH - Singapore/epidemiology RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 900212 DP - 1989 Mar-Apr IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 248-51 SB - M CY - ENGLAND IP - 2 VI - 83 JC - WBU AA - Author EM - 9004 AB - To determine the extent of hantavirus infection in Singapore, serological studies using the indirect immunofluorescent antibody (IFA) test were conducted on commensal rodents and on human patients in 4 diagnostic groups. Virus isolation using a Vero E6 cell line was performed on hantaviral antigen-positive rodent lung tissue. Of 142 rodents and 3 insectivores studied, 37 (26%) were seropositive for IFA. Rattus norvegicus was the predominant species captured, with the highest species-specific seropositive rate of 32% (36 of 113). A hantavirus strain, R36, was isolated from one R. norvegicus. Seropositive rates for human patients were: 8% respectively for dengue haemorrhagic fever suspects and for non-A non-B hepatitis patients, 3% for leptospirosis suspects and 2% for acute nephritis patients. 2 patients had marked liver dysfunction but mild renal involvement. This hepatitis-like manifestation appears to be a clinical variant of hantavirus infection. AD - Department of Community, National University of Singapore. PMID- 2575293 CU - 94 SO - Trans R Soc Trop Med Hyg 1989 Mar-Apr;83(2):248-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 90198515 AU - Adler B AU - Ballard SA AU - Miller SJ AU - Faine S TI - Monoclonal antibodies reacting with serogroup and serovar specific epitopes on different lipopolysaccharide subunits of Leptospira interrogans serovar pomona. LA - Eng MH - Animal MH - Antibodies, Monoclonal/diagnostic use/*immunology MH - Epitopes/*analysis MH - Immunoblotting MH - Leptospira interrogans/classification/*immunology MH - Lipopolysaccharides/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Epitopes) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 900504 DP - 1989 Mar IS - 0920-8534 TA - FEMS Microbiol Immunol PG - 213-8 SB - M CY - NETHERLANDS IP - 4 VI - 1 JC - AO3 AA - Author EM - 9007 AB - Monoclonal antibodies with two kinds of specificities, produced against Leptospira interrogans serovar pomona, were studied by agglutination and immunoblotting. Antibodies reacted either exclusively with serovar pomona or with all members of the Pomona serogroup, but none of the antibodies reacted with representative serovars of other serogroups. Both antibodies recognized epitopes on purified lipopolysaccharide (LPS) from serovar pomona. In immunoblotting experiments the serogroup specific antibody recognized both the major LPS bands of 21 kDa and 26 kDa whereas the serovar specific antibodies reacted only with the 26 kDa band, thus localizing serovar specificity in the 26 kDa band and serogroup specific epitopes on at least two different LPS subunits. AD - Department of Microbiology, Monash University, Melbourne, Australia. PMID- 2483523 CU - 95 SO - FEMS Microbiol Immunol 1989 Mar;1(4):213-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 89163107 AU - Cousins DV AU - Ellis TM AU - Parkinson J AU - McGlashan CH TI - Evidence for sheep as a maintenance host for Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Bacteriuria/*veterinary MH - Disease Reservoirs/*veterinary MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - IgG/analysis MH - IgM/analysis MH - Leptospira interrogans/immunology/*isolation & purification MH - Sheep MH - Sheep Diseases/immunology/*microbiology MH - Support, Non-U.S. Gov't MH - Weil's Disease/immunology/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 890414 DP - 1989 Feb 4 IS - 0042-4900 TA - Vet Rec PG - 123-4 SB - M CY - ENGLAND IP - 5 VI - 124 JC - XBS EM - 8906 AD - Animal Health Laboratories, Department of Agriculture, South Perth, Western Australia. PMID- 2922905 SO - Vet Rec 1989 Feb 4;124(5):123-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 89162390 AU - Bokhout BA AU - Peterse DJ AU - Koger PL AU - Terpstra WJ TI - [The occurrence of hardjo-positive dairy cows in the Northern Netherlands. A prospective serological survey] LA - Dut MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle/*immunology MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Female MH - Human MH - Leptospira interrogans/*immunology MH - Netherlands MH - Population Surveillance MH - Prospective Studies MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890418 DP - 1989 Feb 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 123-30 SB - M CY - NETHERLANDS IP - 3 VI - 114 JC - VRY AA - Author EM - 8906 AB - More than 5000 lactating cows from 82 farms, in the northern part of the Netherlands, were serologically examined for antibodies to Leptospira hardjo. Hardjo-positive cows were found on 52% of the farms with a mean incidence of 23% positive animals. Considerable differences were observed in the percentages hardjo-positive cows per region (7- 30%), as well as in the percentages positive cows per positive farm (22- 46%). With the exception of one region (14%) the percentages of hardjo- positive farms per region hardly differed (average 58%). In addition to the animal survey 488 sera of men working and/or living on cattle-farms were also examined. Twenty-six persons were hardjo-positive. Most of these persons (circa 90%) milked regularly. All seropositive persons were found on farms with hardjo-positive cattle. Results from an inquiry on circa 200 farms indicated, that hardjo-infections probably occur with a higher frequency on larger farms. Finally the results from this survey confirm the observation in the literature, that symptoms of hardjo-infections are more frequently found in the autumn. AD - Afdeling Immunologie, Central Diergeneeskundig Instituut, Lelystad. PMID- 2922744 CU - 91 TT - Het voorkomen van hardjo-positieve melkrunderen in Noord-Nederland. Een orienterend serologisch onderzoek. EA - A SO - Tijdschr Diergeneeskd 1989 Feb 1;114(3):123-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 89304217 AU - Masuzawa T AU - Sekiguchi T AU - Shimizu T AU - Iwamoto Y AU - Morita T AU - Mifuchi I AU - Yanagihara Y TI - Monoclonal antibody against Leptospira interrogans serovar canicola. LA - Eng MH - Animal MH - Antibodies, Bacterial/*immunology MH - Antibodies, Monoclonal/*immunology MH - Biological Availability MH - Immunization MH - Leptospira/*immunology MH - Leptospirosis/immunology/*prevention & control MH - Mice MH - Mice, Inbred BALB C RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 890818 DP - 1989 Feb IS - 0009-2363 TA - Chem Pharm Bull (Tokyo) PG - 414-7 CY - JAPAN IP - 2 VI - 37 JC - CZP AA - Author EM - 8910 AB - Nine cell lines producing monoclonal antibodies (MAbs) against Leptospira interrogans serovar canicola strain Moulton were established by the cell fusion technique. The immunological reactivity of these MAbs with various kinds of serogroups, serovars and strains were examined by microscopic agglutination test (MAT) and enzyme-linked immunosorbent assay (ELISA). MAbs W1-W3 derived from mice, which were immunized with whole cells of the strain Moulton, reacted with the serogroups Canicola, Icterohaemorrhagiae and Pyrogenes. On the other hand, MAbs A1-A6 derived from mice immunized with the outer envelope (OE) fraction, which showed a potent protective activity and was extracted with ammonium hydroxide from the strain Moulton, reacted specifically with the serogroup Canicola alone in MAT. A difference in antigenic structure between subserogroup A (canicola subgroup) and subserogroups B (schueffneri subgroup) of the serogroup Canicola was demonstrated by MAT using the MAbs. All the MAbs clearly agglutinated serovars of subserogroup A except for serovars kamituga, jonsis and bindjei, but did not react with any serovars of subserogroup B. These findings suggest that MAb highly specific to each serovar is readily available by OE immunization and is useful for the classification of Leptospira. PMID- 2743485 CU - 91 SO - Chem Pharm Bull (Tokyo) 1989 Feb;37(2):414-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 89269254 AU - Zaitsev SV AU - Chernukha IuG AU - Evdokimova OA AU - Belov AS TI - [Survival rate of Leptospira pomona in the soil at a natural leptospirosis focus] LA - Rus MH - Animal MH - English Abstract MH - Hamsters MH - *Leptospira MH - *Soil Microbiology PT - JOURNAL ARTICLE DA - 890703 DP - 1989 Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 64-8 SB - M CY - USSR IP - 2 JC - Y9O AA - Author EM - 8909 AB - At the area of a natural focus of leptospirosis (caused by L. pomona) in the Mozdok region of the North Occetic ASSR leptospires were detected by the method of dark field microscopy in 22% of intact soil samples. The presence of pathogenic leptospires in this soil was not confirmed by the method of the biological assay on Syrian golden hamsters. In controlled tests lasting 1-277 days, in 30.4% of cases L. pomona retained their viability, pathogenic and antigenic properties for as long as 74 days, while staying in the soil at the focus of infection with humidity being 15.2-31.4% and pH = 6.7-7.2. 11 Leptospira cultures isolated after staying in the soil retained their pathogenic properties and the death of the animals used in the bioassay from the acute form of leptospiral infection. PMID- 2728704 TT - Vyzhivaemost' leptospir serogruppy pomona v pochve prirodnogo ochaga leptospirosa. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1989 Feb;(2):64-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 89269250 AU - Gol'denshtein ZA AU - Arapov IuA AU - Chernaia RN AU - Mazhnikova GI TI - [Results of ambulatory care and serodiagnosis of leptospirosis in reconvalescents in the Kuban region] LA - Rus MH - Adolescence MH - Adult MH - Antibodies, Bacterial/analysis MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*diagnosis/pathology MH - Male MH - Middle Age MH - *Serodiagnosis MH - USSR RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890703 DP - 1989 Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 46-9 SB - M CY - USSR IP - 2 JC - Y9O AA - Author EM - 8909 AB - The importance of the medical checkup of leptospirosis reconvalscents is shown. In 18.9% of persons having had leptospirosis and placed under medical surveillance the presence of pathological changes has been established after clinical convalescence. Recommendations concerning the prolongation of the period of medical surveillance on leptospirosis reconvalescents with less frequent checkups are given. PMID- 2728701 CU - 91 TT - Rezul'taty dispanserizatsii i serodiagnostiki leptospiroza u rekovalestsentov na Kubani. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1989 Feb;(2):46-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 89222432 AU - Menzies DG AU - Campbell IW AU - Winney RJ TI - Leptospira icterohaemorrhagiae infection presenting as acute renal failure. LA - Eng MH - Atrial Fibrillation/etiology MH - Case Report MH - Diagnosis, Differential MH - Human MH - Kidney Failure, Acute/diagnosis/*etiology MH - Male MH - Middle Age MH - Weil's Disease/*complications/diagnosis PT - JOURNAL ARTICLE DA - 890526 DP - 1989 Feb IS - 0036-9330 TA - Scott Med J PG - 410 SB - M CY - SCOTLAND IP - 1 VI - 34 JC - UJK AA - Author EM - 8908 AB - The features of leptospiral infection should be sought in all cases of acute renal failure since management depends on the recognition of the clinical syndrome and serological confirmation is usually delayed. Hepatic and renal involvement is usual but renal failure without significant derangement of liver function is described. AD - Department of Medicine, Victoria Hospital, Kirkcaldy. PMID- 2711177 SO - Scott Med J 1989 Feb;34(1):410 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 89162391 AU - Hartman EG AU - Franken P AU - Bokhout BA AU - Peterse DJ TI - [Leptospirosis in cattle; milker's fever in cattle farmers] LA - Dut MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis/epidemiology/prevention & control MH - *Dairying MH - English Abstract MH - Europe MH - Female MH - Human MH - Leptospirosis/epidemiology/prevention & control/*veterinary MH - Netherlands MH - Occupational Diseases/*etiology MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 890418 DP - 1989 Feb 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 131-5 SB - M CY - NETHERLANDS IP - 3 VI - 114 JC - VRY AA - Author EM - 8906 AB - In this paper the symptomatology, epidemiology, and diagnosis of Leptospira interrogans serovar hardjo infections in cattle are reviewed. The possibilities on monitoring and control of this disease in both foreign countries and the Netherlands are discussed. Special attention is paid to the zoonotic aspects of the infection (dairy fever). AD - Gezondheidsdienst voor Dieren in Gelderland, Velp Gld. RF - 0 PMID- 2646755 CU - 90 TT - Leptospirose bij runderen; melkerskoorts bij de veehouders. EA - A SO - Tijdschr Diergeneeskd 1989 Feb 1;114(3):131-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 89125558 AU - Doherty JP AU - Adler B AU - Rood JI AU - Billington SJ AU - Faine S TI - Expression of two conserved leptospiral antigens in Escherichia coli. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/immunology MH - Antigens, Bacterial/biosynthesis/*genetics/immunology MH - Blotting, Western MH - Cloning, Molecular MH - Comparative Study MH - Electrophoresis, Polyacrylamide Gel MH - Escherichia coli/genetics MH - Leptospira interrogans/*genetics/immunology MH - Plasmids MH - Recombinant Proteins/biosynthesis/genetics/immunology MH - Restriction Mapping MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Plasmids) RN - 0 (Recombinant Proteins) PT - JOURNAL ARTICLE DA - 890315 DP - 1989 Feb IS - 0022-2615 TA - J Med Microbiol PG - 143-9 SB - M CY - ENGLAND IP - 2 VI - 28 JC - J2N AA - Author EM - 8905 AB - The genes encoding two protein antigens of Leptospira interrogans serovar pomona were cloned and expressed in Escherichia coli. Rabbit antisera raised against the cloned proteins, designated p12 and p20, were used to identify the antigens in Western blots of disrupted leptospiral cells. The proteins p12 and p20 were conserved within the genus Leptospira and were not detected in Leptonema illini. Although both proteins were present in leptospiral outer envelope preparations they did not elicit the production of agglutinating or opsonising antibodies. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 2644433 CU - 92 SO - J Med Microbiol 1989 Feb;28(2):143-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 89188305 AU - Treml F AU - Hejlicek K AU - Svoboda M AU - Mahelkova K TI - [Occurrence of leptospiral antibodies in dogs in Brno and the surrounding area] LA - Cze MH - Animal MH - Antibodies, Bacterial/*analysis MH - Dogs/*microbiology MH - English Abstract MH - Leptospira/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890510 DP - 1989 Feb IS - 0375-8427 TA - Vet Med (Praha) PG - 121-8 CY - CZECHOSLOVAKIA IP - 2 VI - 34 JC - XBP AA - Author EM - 8907 AB - A serological examination by the microagglutination reaction of lysis (RMAL) was performed with 12 leptospira strains to investigate 1272 blood serums of dogs coming for various kinds of treatment to the outpatient ward of the veterinary hospital. The higher infestation rate was recorded in the dogs from outside the city (14.08%) than in the city dogs (7.96%). A considerably high infestation was found in the dogs of the service breeds (13.47%). The males were infested more frequently (10.99%) than the bitches (7.22%). As for age, young dogs until the age of one year were found to be infested more frequently. Separate significant titres were demonstrated with the leptospira of the Grippotyphosa, Icterohaemorrhagiae, Sejroe, and Australis (L. bratislava) serological groups. Reactions with the leptospira of other groups were recorded only at low titres: they were as coagglutinations with parallel high-titre reactions with the leptospira of the Grippotyphosa and Icterohaemorrhagiae groups. PMID- 2494790 CU - 91 TT - Vyskyt leptospirovych protilatek u psu brnenske a mimobrnenske aglomerace. EA - A SO - Vet Med (Praha) 1989 Feb;34(2):121-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 89168488 AU - Rivest N AU - Jobin J AU - Gaudreau C TI - Leptospirosis: a diagnosis to be kept in mind. LA - Eng LA - Fre MH - Aged MH - Animal MH - Case Report MH - Human MH - Leptospirosis/*diagnosis/transmission MH - Male MH - Zoonoses/transmission PT - JOURNAL ARTICLE DA - 890505 DP - 1989 Jan 21 IS - 0382-232X TA - Can Dis Wkly Rep PG - 13-6 CY - CANADA IP - 3 VI - 15 JC - CWA EM - 8907 PMID- 2924357 SO - Can Dis Wkly Rep 1989 Jan 21;15(3):13-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 89189264 AU - Zhang WH AU - Bai XF AU - Deng QD AU - Nie DK TI - Investigation on monoclonal antibodies against two serovars of the icterohaemorrhagiae serogroup of Leptospira. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*immunology MH - Antibodies, Monoclonal/diagnostic use/*immunology MH - Antibody Specificity MH - Hybridomas MH - Leptospira interrogans/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 890504 DP - 1989 Jan IS - 0176-6724 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 329-36 SB - M CY - GERMANY, WEST IP - 3 VI - 270 JC - Y55 AA - Author EM - 8907 AB - By means of the cell fusion technique, two hybridoma cell lines, V-1 and H2-1 have been obtained. V-1 cells secrete monoclonal antibody against serovars icterohaemorrhagiae and dakota. The H2-1 cell line secretes serovar-specific monoclonal antibody against serovar H2. These monoclonal antibodies have been successfully used in serovar-typing of leptospires isolated in China. The results of identification of leptospires by using monoclonal antibodies showed total coincidence with that by the traditional cross agglutinin absorption test and factor antiserum method. It was confirmed by using monoclonal antibody that the serological agglutination totally paralleled with animal protection. On the basis of the study, a concept was proposed that the agglutination in vitro and the protection in vivo are different manifestations in different reaction systems from the same antibody (antibodies) stimulated by a component(s) of the surface antigen of leptospires. AD - Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing, Peoples Republic of China. PMID- 2929187 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1989 Jan;270(3):329-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 89154734 AU - Lecour H AU - Miranda M AU - Magro C AU - Rocha A AU - Goncalves V TI - Human leptospirosis--a review of 50 cases. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Aged, 80 and over MH - Antibodies, Bacterial/analysis MH - Child MH - Child, Preschool MH - Female MH - Fever MH - Human MH - Kidney/pathology MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - *Leptospirosis/epidemiology/pathology/therapy MH - Male MH - Meningitis, Aseptic/epidemiology MH - Middle Age MH - Muscles/pathology MH - Penicillins/therapeutic use MH - *Weil's Disease/epidemiology/pathology/therapy RN - 0 (Antibodies, Bacterial) RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 890417 DP - 1989 Jan-Feb IS - 0300-8126 TA - Infection PG - 8-12 SB - M CY - GERMANY, WEST IP - 1 VI - 17 JC - GO8 AA - Author EM - 8906 AB - Epidemiological and clinical aspects of 50 consecutive patients, 47 adults and three children, hospitalized between 1977 and 1987 for human leptospirosis, were reviewed. 45 (90%) of the patients were from rural regions. 32 (64%) cases occurred in individuals at occupational risk for the infection. 35 (70%) cases were registered in the warm season. The source of infection was known in 34 (68%) cases. Weil's disease was diagnosed in 31 (62%) patients, aseptic meningitis in 12 (24%) and acute unexplained fever in seven (14%). Haemodialysis was required for 11 (35%) patients with Weil's disease. Three (6%) patients died. Cause of death was massive gastrointestinal haemorrhage in two and renal failure in one. Leptospira icterohaemorrhagiae was responsible for 39 (78%) cases, Leptospira canicola for six (12%), Leptospira grippotyphosa for two (4%), and Leptospira australis, Leptospira ballum and Leptospira sejroe, for one case each. A muscle biopsy was performed in six patients and a renal biopsy in three. Focal necrotic muscular changes, with mild mononuclear infiltrate, were found. Pigmented casts in distal convoluted tubules, mild interstitial inflammatory infiltrate and mesangial enlargement of some glomeruli were observed in kidney biopsies. A good knowledge of the protean clinical manifestations of leptospirosis and an accurate laboratory study are required for a correct diagnosis. AD - Department of Infectious Diseases, School of Medicine, Hospital S. Joao, Porto. PMID- 2921094 CU - 92 SO - Infection 1989 Jan-Feb;17(1):8-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 90038441 AU - Sebek Z AU - Sixl W AU - Reinthaler F AU - Valova M AU - Schneeweiss W AU - Stunzner D AU - Mascher F TI - Results of serological examination for leptospirosis of domestic and wild animals in the Upper Nile province (Sudan). LA - Eng MH - Animal MH - Animals, Domestic/*microbiology MH - Animals, Wild/*microbiology MH - Leptospirosis/epidemiology/*veterinary MH - Seroepidemiologic Methods MH - Sudan/epidemiology PT - JOURNAL ARTICLE DA - 891218 DP - 1989 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 337-45 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 33 JC - IEV AA - Author EM - 9002 AB - 195 domestic and 766 wild animals were serologically examined for leptospirosis. Cattle was found to be positive at titres 1 greater than or equal to 400 in 63.5%, namely 50.6% for Tarassovi, 17.1% for Sejroe- Hebdomadis, 9.4% for Bataviae, 1.2-3.5% for Icterohaemorrhagiae, Cynopteri, Autumnalis, Australis, Pomona and Grippotyphosa. Sera from 35 animals reacted with the serovars from two or more serogroups. Of 7 sheep 1 was positive for Pomona and 18 goats proved to be negative. 10.2% of wild mammals were positive at titres 1 greater than or equal to 100, namely 3.5% for Icterohaemorrhagiae, 3.1% for Javanica, 1.7% for Pomona and 0.1-0.8% for Sejroe-Hebdomadis, Grippotyphosa Pyrogenes, Australis, Ballum, Bataviae, Cynopteri and Canicola. The sera of 10 animals were simultaneously positive with the serovars of two serogroups. Erinaceus albiventris, Eidolon helvum, Tadarida condylura and T. pumila, Cercopithecus aethiops, Genetta sp., Ichneumonia albicauda, Canis adustus and C. aureus, Felis silvestris, Leptailurus serval, Arvicanthis niloticus, Mus sp. and species from the subfamilies Tragelaphniae, Reduncinae and Gazellinae were serologically positive. The positivity rate in rodents was only 1.2%. AD - National Reference Laboratory for Leptospires, District Centre of Hygiene, Jihlava, Czechoslovakia. PMID- 2809189 SO - J Hyg Epidemiol Microbiol Immunol 1989;33(3):337-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 90019808 AU - Kotova IN AU - Pavlova LV AU - Beliak GM TI - [Discriminant analysis for the prognostication in icterohemorrhagic leptospirosis] LA - Rus MH - Adult MH - Comparative Study MH - Discriminant Analysis MH - Female MH - Human MH - Male MH - Prognosis MH - Weil's Disease/classification/*diagnosis PT - JOURNAL ARTICLE DA - 891120 DP - 1989 IS - 0038-5077 TA - Sov Med PG - 93-6 CY - USSR IP - 7 JC - UW7 EM - 9001 PMID- 2799543 TT - Diskriminantnyi analiz dlia prognizoravaniia ikterogemorragicheskogo leptospiroza. SO - Sov Med 1989;(7):93-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 89388635 AU - Pokrovskii VI AU - Radzivil GG AU - Zmyzgova AV AU - Shalygina NB AU - Beloborodov VB TI - [Hemosorption in infectious pathology] LA - Rus MH - English Abstract MH - *Hemoperfusion MH - Hepatitis, Viral, Human/*therapy MH - Human MH - Leptospirosis/*therapy MH - Meningitis/*therapy MH - Shock, Septic/*therapy PT - JOURNAL ARTICLE DA - 891020 DP - 1989 IS - 0040-3660 TA - Ter Arkh PG - 130-4 SB - M CY - USSR IP - 5 VI - 61 JC - VLU AA - Author EM - 8912 AB - Hemosorption was used for the treatment of 152 patients with purulent meningitis, sepsis complicated by shock, virus hepatitis and leptospirosis. A favorable effect of hemosorption in infections was based on highly effective correction of microcirculatory disorders as a result of the removal of high molecular substances of microbic and endogenous origin. PMID- 2781476 TT - Gemosorbtsiia pri infektsionnoi patologii. EA - A SO - Ter Arkh 1989;61(5):130-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 89381680 AU - Schoone GJ AU - Everard CO AU - Korver H AU - Carrington DG AU - Inniss VA AU - Baulu J AU - Terpstra WJ TI - An immunoprotective monoclonal antibody directed against Leptospira interrogans serovar copenhageni. LA - Eng MH - Animal MH - Antibodies, Monoclonal/*biosynthesis MH - Cercopithecus aethiops MH - Dogs MH - Hamsters MH - Hybridomas/immunology MH - *Immunization, Passive MH - Leptospira interrogans/*immunology MH - Mesocricetus MH - Mice MH - Mice, Inbred BALB C/immunology MH - Species Specificity RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 891023 DP - 1989 Jan IS - 0022-1287 TA - J Gen Microbiol PG - 73-8 SB - M CY - ENGLAND VI - 135 ( Pt 1) JC - I87 AA - Author EM - 8912 AB - A monoclonal antibody (mAb) was prepared by hybridoma technology in BALB/c mice immunized to Leptospira interrogans serovar copenhageni. This mAb agglutinated serovars copenhageni and icterohaemorrhagiae to high titres and protected hamsters, dogs and monkeys against challenge with a virulent strain of serovar copenhageni. The mAb gave protection to hamsters at dilutions up to 1 in 1000; at a 1 in 10 dilution the protective effect lasted for at least two weeks. Biochemical analysis by SDS-PAGE and Western blotting indicated that this mAb reacted with an epitope of a carbohydrate nature. AD - N. H. Swellengrebel Laboratory of Tropical Hygiene, Royal Tropical Institute, Amsterdam, The Netherlands. PMID- 2778433 CU - 91 SO - J Gen Microbiol 1989 Jan;135 ( Pt 1):73-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 89360175 AU - Allen P AU - Raftery S AU - Phelan D TI - Massive pulmonary haemorrhage due to leptospirosis. LA - Eng MH - Adult MH - Case Report MH - Hemorrhage/*etiology/therapy MH - Human MH - Leptospirosis/*complications/drug therapy/physiopathology MH - Lung Diseases/*etiology/therapy MH - Male MH - Penicillin G/therapeutic use MH - Respiratory Therapy RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 891011 DP - 1989 IS - 0342-4642 TA - Intensive Care Med PG - 322-4 SB - M CY - UNITED STATES IP - 5 VI - 15 JC - H2J AA - Author EM - 8912 AB - A young man with leptospirosis developed massive pulmonary haemorrhage. This was remarkable both in its severity and in its occurrence early in the clinical course - before the onset or presence of jaundice, renal failure or of a serological diagnosis. It occurred in the absence of a coagulopathy or thrombocytopenia and presumably was a consequence of the capillary fragility characteristic of the disease - perhaps precipitated in this instance by mechanical ventilation. AD - Department of Anaesthesia and Intensive Care, Mater Misericordiae Hospital, Dublin, Ireland. PMID- 2768647 SO - Intensive Care Med 1989;15(5):322-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 89304292 AU - Law-Koune JD AU - Duval G AU - Michault A AU - Baranton G AU - De Camaret P AU - Lemahieu JM AU - Van-der-Linden T TI - [Human leptospirosis in Reunion Island. A 3-year epidemiological study (1985-1987)] LA - Fre MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Demography MH - English Abstract MH - Female MH - Human MH - Indian Ocean Islands MH - Leptospirosis/*epidemiology/mortality MH - Male MH - Middle Age MH - Seasons MH - Sex Factors PT - JOURNAL ARTICLE DA - 890825 DP - 1989 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 185-91 SB - M CY - FRANCE IP - 2 VI - 82 JC - C4G AA - Author EM - 8910 AB - During a three-year period (1985-1987), in Reunion Island, 252 cases of leptospirosis were clinically diagnosed in humans, and serologically confirmed. The epidemiological study showed a significant male predominance, presence during all ages of life; no month and no geographical zone are spared but maximal incidences are noted during periods of and in localities with the most important rainfall. Severe forms are frequent but mortality remains low. AD - Service de Reanimation, Hopital de Saint-Pierre, Reunion. PMID- 2743523 TT - La leptospirose humaine a la Reunion. Etude epidemiologique sur trois annees (1985-1987). EA - A SO - Bull Soc Pathol Exot Filiales 1989;82(2):185-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 89226927 AU - Petit J AU - Jusserand D AU - Eustache ML AU - Bokobza B AU - Metayer J AU - Bourquelot R AU - Oksenhendler G AU - Winckler C TI - [Leptospirosis caused by Leptospira icterohaemorrhagiae of the pseudo- surgical type: a case] LA - Fre MH - Acute Disease MH - Aged MH - Case Report MH - Cholecystitis/*diagnosis MH - English Abstract MH - Female MH - Human MH - Jaundice/diagnosis/etiology MH - Leptospira interrogans MH - Weil's Disease/*diagnosis/microbiology PT - JOURNAL ARTICLE DA - 890608 DP - 1989 IS - 0003-3944 TA - Ann Chir PG - 220-3 CY - FRANCE IP - 3 VI - 43 JC - 50E AA - Author EM - 8908 AB - The authors report a case of fatal leptospirosis due to Leptospira icterohaemorrhagiae revealed by typical signs of acute cholecystitis and associated with pancreatitis in a 73 year old patient presenting with gallstones. The initial clinical findings were highly suggestive of severe but typical cholecystitis and the final diagnosis was only considered when the patient's condition worsened despite surgery, with increasing obstructive jaundice and multiple organ failure. Pancreatitis was an autopsy finding. Misleading, especially gastrointestinal symptoms are frequent in leptospirosis. Hence an early diagnosis is an essential condition for a successful antibiotic management in severe cases of leptospirosis. This possibility should be considered whenever a patient presents with infectious obstructive jaundice. The patient has to be questioned concerning possible contact with contaminated animals and, when in doubt, the presence of specific antibodies should be investigated. PMID- 2712506 TT - Leptospirose a leptospira ictero-hemorrhagiae a forme pseudo- chirurgicale: une observation. EA - A SO - Ann Chir 1989;43(3):220-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 90158289 AU - Zhang WH AU - Bai XF AU - Nie DK AU - Deng QD TI - An application of monoclonal antibodies to identification of leptospires of serogroup icterohaemorrhagiae found in China. LA - Eng MH - Animal MH - *Antibodies, Monoclonal MH - *Bacterial Typing Techniques MH - China MH - Leptospira interrogans/*classification MH - Mice RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 900326 DP - 1989 IS - 0385-5600 TA - Microbiol Immunol PG - 1039-43 SB - M CY - JAPAN IP - 12 VI - 33 JC - MX7 AA - Author EM - 9005 AB - For the purpose of improving the procedures of identification of leptospires, a set of 5 monoclonal antibodies with different serological reactivity against serovars of Leptospira interrogans Icterohaemorrhagiae serogroup isolated in China was developed. One hundred and eight strains isolated from epidemic fields in 5 provinces in southern China were distinctly identified into 4 serovars of Icterohaemorrhagiae serogroup by the monoclonal antibody procedure, i.e., 98 isolates were identified as serovar lai, 7 as icterohaemorrhagiae, 2 as copenhageni, and 1 as H2. Factor antiserum procedure was used at the same time as control for typing these strains and an identical result was obtained. AD - Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing. PMID- 2695789 CU - 91 SO - Microbiol Immunol 1989;33(12):1039-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 90133637 AU - Rudland SV TI - Leptospirosis. Do you consider the diagnosis? LA - Eng MH - Animal MH - Antibiotics/therapeutic use MH - Disease Reservoirs MH - Human MH - Leptospira/classification MH - Leptospirosis/*diagnosis/drug therapy/microbiology MH - Rats MH - Weil's Disease/*diagnosis RN - 0 (Antibiotics) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 900302 DP - 1989 Winter IS - 0035-9033 TA - J R Nav Med Serv PG - 143-6 CY - ENGLAND IP - 3 VI - 75 JC - JVL AA - Author EM - 9005 AB - Patients with Leptospirosis, usually a water borne zoonotic disease, are likely to present themselves to Royal Naval primary health carers, who deal with a young active population, frequently participating in watersports. Leptospira, which belong to the order Spirochaetaceae, comprise of two distinct species. Within each species there are a number of serologically different serovars (serotypes), arranged in related serogroups. L. interrogans var Icterhaemorrhagiae and L. interrogans var Hebdomadis serovar hardjo are the most commonly reported organisms in Great Britain. Traditionally water and sewage workers have been amongst those most frequently infected, but with improved health care awareness this group has been overtaken by farmworkers, and a growing group of people engaged in aquatic sports. Symptoms of Leptospiral infection vary in severity from a mild flu-like illness to symptoms resulting from severe renal, hepatic or meningeal involvement. Mild symptoms respond to oral penicillin, erythromycin or tetracyclines, whilst more serious illness requires i.v. penicillin and supportive nursing. Spirochaetes can be detected in culture using darkground microscopy, and sero-conversion detected by IgM specific dot ELISA techniques. Suspected sera should be sent to PHLS Leptospira Reference Unit, County Hospital, Hereford. HR1 2ER. (Tel: 0432 277117). RF - 20 PMID- 2693693 CU - 91 SO - J R Nav Med Serv 1989 Winter;75(3):143-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 90021504 AU - Chong Y TI - Application of serologic diagnosis of tsutsugamushi disease (scrub typhus) in Korea where the disease was recently recognized to be endemic. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Epidemiologic Methods MH - Human MH - Korea MH - Middle Age MH - Scrub Typhus/*diagnosis/epidemiology MH - Serodiagnosis PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 891103 DP - 1989 IS - 0513-5796 TA - Yonsei Med J PG - 111-7 CY - KOREA IP - 2 VI - 30 JC - XRR AA - Author EM - 9001 AB - In Korea, tsutsugamushi disease is a recently recognized infection. It has become clear that it is more prevalent than leptospirosis or hemorrhagic fever with renal syndrome. Accurate diagnosis of the disease is necessary for the selection of effective antimicrobial agents which can prevent fatalities and shorten the course. For the diagnosis, various serologic tests are used. Sensitivity and specificity of a test depend on various factors. In this report, microbiological aspects of the infection were briefly described and the Weil-Felix, indirect immunofluorescence and indirect immunoperoxidase tests were compared for their applicability in routine use and usefulness in the diagnosis. Their interpretations were also briefly discussed. RF - 35 PMID- 2678763 CU - 90 SO - Yonsei Med J 1989;30(2):111-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 89306635 AU - Sebek Z AU - Sixl W AU - Sixl-Voigt B AU - Kock M AU - Stunzner D AU - Valova M TI - First evidence of the leptospirosis natural foci of the serotype Saxkoebing in Austria. LA - Eng MH - Animal MH - Animals, Wild/immunology/*microbiology MH - Antibodies, Bacterial/isolation & purification MH - Austria MH - Leptospira/classification/immunology/*isolation & purification MH - Microtinae/microbiology MH - Serotyping RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890822 DP - 1989 IS - 0300-807X TA - Geogr Med Suppl PG - 17-22 SB - M CY - HUNGARY VI - 2 JC - AUN AA - Author EM - 8910 AB - The authors examined serologically and bacteriologically 129 wild living small mammals (9 species) in Neumarkt, in Styria. A total of 17 animals were positive (all Microtus agrestis), of these 10 serologically (6 with L. saxkoebing, 3 with L. grippotyphosa and 1 with L. sorexjalna) and 7 bacteriologically. Of the 7 isolated leptospirae- strains one did not survive up to typing, the 6 remaining were identified as L. saxkoebing. It is the first evidence of the existence of leptospirosis natural foci of the serovar saxkoebing in Austria and at the same time the first isolation of L. saxkoebing from Microtus agrestis in Central Europe. The serovar saxkoebing, which BORG-PETERSEN described in the year 1942 (1943) and isolated from the yellow-neck mouse (Apodemus flavicollis) is found in most European countries (KATHE and MOCHMANN, 1967), may, however not be found in some regions although its main reservoir, the yellow-neck mouse dwells, as SEBEK (1965) and SEBEK and ROSICKY (1974) drew attention to in Czechoslovakia. In Austria, in fact L. saxkoebing antibodies have been demonstrated in wild- and also domestic-animals (SEBEK, et. al., 1973b, 1976a, 1976b), however, a reliable proof of these serovars was not found. AD - Institute of Hygiene, University of Graz, Austria. RO - M:MWS PMID- 2663645 LR - 900925 CU - 91 SO - Geogr Med Suppl 1989;2:17-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 89148830 AU - Bolin CA AU - Thiermann AB AU - Handsaker AL AU - Foley JW TI - Effect of vaccination with a pentavalent leptospiral vaccine on Leptospira interrogans serovar hardjo type hardjo-bovis infection of pregnant cattle. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Female MH - Fetal Death/etiology/veterinary MH - Fluorescent Antibody Technique MH - Kidney/microbiology MH - Leptospira interrogans/*immunology MH - Male MH - Pregnancy MH - Pregnancy Complications, Infectious/prevention & control/*veterinary MH - Vaccination/veterinary MH - Weil's Disease/complications/prevention & control/*veterinary RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 890329 DP - 1989 Jan IS - 0002-9645 TA - Am J Vet Res PG - 161-5 SB - M CY - UNITED STATES IP - 1 VI - 50 JC - 40C AA - Author EM - 8906 AB - Effectiveness of a pentavalent leptospiral vaccine to protect cattle from infection and reproductive problems caused by Leptospira interrogans serovar hardjo type hardjo-bovis was evaluated. Seven cows were vaccinated once and 8 cows were vaccinated twice with a USDA- licensed pentavalent leptospiral vaccine. Five cows were maintained as nonvaccinated controls. Cows were bred 1 to 2 months after the last vaccination. During the 4th to 6th month of gestation, all cows were challenge exposed on 4 occasions by conjunctival instillation of 10(8) serovar hardjo type hardjo-bovis organisms and on 3 occasions by conjunctival instillation of urine from a cow shedding hardjo-bovis. All control cows and 13 of 15 vaccinated cows became infected and shed leptospires in the urine. Leptospires were detected in fewer urine samples collected from vaccinated cows, compared with those collected from control cows. Four stillborn calves and 3 weak calves were born to control and vaccinated cows. Leptospires were detected in the kidneys of 11 apparently healthy calves born to vaccinated and control cows. Agglutinating antibodies were not detected in the precolostral serum of these calves. AD - USDA, National Animal Disease Center, Ames, IA 50010. PMID- 2645816 CU - 91 SO - Am J Vet Res 1989 Jan;50(1):161-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 90101055 AU - Pereira MC TI - The epidemiology of leptospirosis in Portugal. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Reservoirs MH - Human MH - Leptospirosis/*epidemiology MH - Portugal MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 900129 DP - 1989 Jan-Feb IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 132 SB - M CY - ENGLAND IP - 1 VI - 83 JC - WBU EM - 9004 AD - Instituto de Higiene e Medicina Tropical (Laboratorio de Leptospiras, Lisboa, Portugal. PMID- 2603191 SO - Trans R Soc Trop Med Hyg 1989 Jan-Feb;83(1):132 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 90093009 AU - Sebek Z AU - Sixl W AU - Reinthaler F AU - Abdel-Nabi O AU - Stunzner D AU - Schneeweiss W AU - Mascher F AU - Valova M TI - Leptospirosis in the Melut district--upper Nile province (south Sudan)-- an overview. LA - Eng MH - Animal MH - Animals, Domestic/*immunology MH - Animals, Wild/immunology MH - Antibodies, Bacterial/*isolation & purification MH - Leptospira/classification/*immunology MH - Serotyping MH - Sudan RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900208 DP - 1989 IS - 0300-807X TA - Geogr Med Suppl PG - 161-78 SB - M CY - HUNGARY VI - 5 JC - AUN AA - Author EM - 9004 AB - The authors examined 195 domestic animals for leptospirosis serologically in Sudan (170 cattle, 7 sheep and 18 goats) and 771 wild animals (36 species) with 13 serovars from 13 serogroups. 54% of domestic animals namely, 108 cattle and 1 sheep were positive in titer levels of 1:400 and higher. Cattle sera with the serovars of the serogroup Icterohaemorrhagiae were 2.4% positive with Cynopteri 2.4%, Autumnalis 3.5%, Australis 1.2%, Pomona 2.9%, Grippotyphosa 2.9%, Hebdonadis 17.1%, Bataviae 9.4% and Tarassovi 50.6%. Only one Numida meleagris of the 54 wild birds (14 species) was positive in low titer level of 1:100 with L. canicola. Seventy (9.8%) of the 717 wild mammals (22 species) examined were positive namely with the serovars of the serogroups Icterohaemorrhagiae 3.4%, Javanica 3.0%, Pomona 2.0%, Grippotyphosa 0.7%, Hebdomadis 0.4%, Ballum, Australis, Pyrogenes, Bataviae each 0.3% and Cynopteri 0.1%, whereby sera from 7 animals reacted simultaneously with the serovars of two serogroups. With regard to the species, positive reactions were found in Erinaceus albiventris, Eidolon helbum, Cercopithecus aethiops, Genetta spec., Canis adustus et aurus, Felis silvestris, Leptailurus serval, Arvicanthis niloticus, Mastomys spec., Mus spec., Gazella spec., Tragelaphus spec. The positivity in rodents was very low - 1.2%. AD - National Reference Laboratory for Leptospirosts, Jihlava, Czechoslovakia. RO - M:MWS PMID- 2599388 LR - 900925 CU - 91 SO - Geogr Med Suppl 1989;5:161-78 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 90093008 AU - Sebek Z AU - Miorini I AU - Brosch R AU - Buchrieser C AU - Buchrieser V AU - Sixl W AU - Valova M TI - A survey of leptospirological studies carried out on the Cape Verde Islands. LA - Eng MH - Animal MH - Animals, Domestic/*immunology MH - Animals, Wild/immunology MH - Antibodies, Bacterial/*isolation & purification MH - Atlantic Islands MH - Human MH - Leptospira/classification/*immunology MH - Serotyping RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900208 DP - 1989 IS - 0300-807X TA - Geogr Med Suppl PG - 153-60 SB - M CY - HUNGARY VI - 5 JC - AUN AA - Author EM - 9004 AB - The authors subjected 611 human sera, 1295 sera of domestic and 211 sera of wild living animals from two islands of the Cape Verde archipelago to serological tests for leptospirosis. Among the human sera 7.2% reacted positively. Antibodies to L. bratislava of the serogroup Australis were most frequent (59.1% of all positive sera). Antibodies to L. icterohaemorrhagiae were found in 1.3% of the sera tested, to L. sejroe in 1.1%, to L. canicola in 0.7%, to L. pyrogenes in 0.3% and to L. pomona, L. bulgarica and L. grippotyphosa in 0.2% each. The existence of natural foci of leptospiroses could not be proved since tests of 211 wild-living mammals were all negative. The investigation of domestic animal sera showed a positivity of 3.1% with goats being positive most frequently (85% of all positive sera), followed by donkeys with 3.3% and cattle with 2.0%. Sera of dogs, sheep and pigs were all negative. The results indicate that anthropurgic foci exist on the Cape Verde Islands. AD - Department of Parasitology, District Hygiene Center, Jihlava, Czechoslovakia. RO - M:MWS PMID- 2599387 LR - 900925 CU - 91 SO - Geogr Med Suppl 1989;5:153-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 90060761 AU - Sebek Z AU - Sixl W AU - Valova M AU - Linck G AU - Kock M AU - Reinthaler FF AU - Marth E TI - Results of leptospirosis examinations of human sera from El Salvador. LA - Eng MH - Adolescence MH - Adult MH - Antibodies, Bacterial/*analysis MH - Child MH - Cross-Sectional Studies MH - El Salvador/epidemiology MH - Female MH - Human MH - Incidence MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Serotyping MH - Weil's Disease/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900104 DP - 1989 IS - 0300-807X TA - Geogr Med Suppl PG - 61-72 SB - M CY - HUNGARY VI - 3 JC - AUN AA - Author EM - 9003 AB - The authors examined 984 human sera for leptospirosis with the serovars from 15 serogroups serologically in 15 localities of El Salvador. In 17.5% of the sera the following reactions were found with serovars of 13 serogroups: Australis 6.8%, Pomona 5.5%, Grippotyphosa 3.2%, Icterohaemorrhagiae and Tarassovi each 2.1%, Javanica, Canicola, Pyrogenes, Cynopteri, Autumnalis, Sejroe, Hebdomadis, Bataviae, Shermani, between 0.2%-1.4%. Men showed a 18.5% and women 17.0% positive reaction. Positivity increases with an increase in age, an increase was shown from 11.5% in the group of up to 10 years, to 40.4% in the group of 51 to 60 years, in the last age group of over 60 years a decrease was shown of 34.7%. In 8 localities we were able to compare the serological positivity of the population, the highest percentages were found in Fey Esperanza 35.1%, San Jose de la Montana 31.6% and Domus Maria 27.8%, the lowest in Credisa 6.4% and Ametepec 7.6%. AD - District-Hygiene-Station, JIHLAVA/CSSR. RO - M:MWS PMID- 2583506 LR - 900925 CU - 91 SO - Geogr Med Suppl 1989;3:61-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 90060760 AU - Sebek Z AU - Sixl W AU - Valova M AU - Marth E AU - Kock M AU - Reinthaler FF TI - Serological investigations for leptospirosis in humans in Columbia. LA - Eng MH - Adolescence MH - Adult MH - Antibodies, Bacterial/*analysis MH - Child MH - Colombia/epidemiology MH - Cross-Sectional Studies MH - Female MH - Human MH - Incidence MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Serotyping MH - Weil's Disease/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900104 DP - 1989 IS - 0300-807X TA - Geogr Med Suppl PG - 51-60 SB - M CY - HUNGARY VI - 3 JC - AUN AA - Author EM - 9003 AB - The authors examined serologically 353 clinically healthy persons in 5 localities in South Columbia for leptospirosis using the MAL-reaction with 15 serovars of 15 serogroups. The positivity was high - 18.4% namely with the serovars of the serogroups Icterohaemorrhagiae, Canicola, Pyrogenes, Australis, Pomona, Grippotyphosa, Sejroe, Hebdomadis, Bataviae, Panama and Shermani. Sera reacted positive in titer levels of 1:400 and higher only with the serovars of the serogroups Icterohaemorrhagiae, Canicola, Australis, Grippotyphosa, Sejroe, Hebdomadis, Panama and Shermani. In the total positivity were the serovars of the serogroups Icterohaemorrhagiae with 30.8%, Grippotyphosa with 23.1%, Australis with 15.4%, Panama and Pyrogenes with 10.8% each, Pomona with 6.2%, Shermani with 4.6% and Canicola, Sejroe, Hebdomadis, Bataviae with 3.1% each. The high positivity of the sera from the Mocoa for L.grippotyphosa was surprising - 20.7%. AD - Reference Laboratory for Leptospirosis, District-Hygiene-Station, JIHLAVA/CSSR. RO - M:MWS RO - M:MWS RO - M:MWS PMID- 2583505 LR - 900925 CU - 91 SO - Geogr Med Suppl 1989;3:51-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 90060758 AU - Sebek Z AU - Chambouris R AU - Sixl W AU - Stunzner D AU - Kock M TI - [Leptospirosis in dogs in Greece] LA - Ger MH - Animal MH - Antibodies, Bacterial/*analysis MH - Dog Diseases/*immunology MH - Dogs MH - Greece MH - Hemagglutination Tests/veterinary MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Serotyping RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900104 DP - 1989 IS - 0300-807X TA - Geogr Med Suppl PG - 29-39 SB - M CY - HUNGARY VI - 3 JC - AUN EM - 9003 RO - M:MWS PMID- 2583503 LR - 900925 CU - 91 TT - Zur Leptospirose bei Hunden in Griechenland. SO - Geogr Med Suppl 1989;3:29-39 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 90060753 AU - Sebek Z AU - Sixl W AU - Valova M AU - Schaffler R TI - Leptospirosis in man, in wild and in domestic animals at waste disposal sites in Cairo. LA - Eng MH - Animal MH - Animals, Domestic/*immunology MH - Animals, Wild/*immunology MH - Antibodies, Bacterial/*analysis MH - Cross-Sectional Studies MH - Egypt MH - Human MH - Incidence MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology/transmission/veterinary MH - *Refuse Disposal MH - Serotyping MH - Weil's Disease/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900104 DP - 1989 IS - 0300-807X TA - Geogr Med Suppl PG - 141-50 SB - M CY - HUNGARY VI - 3 JC - AUN AA - Author EM - 9003 AB - The authors examined 65 Rattus rattus, 28 pigs, 12 donkeys, 67 goats, 5 sheep, 1 cow and 1 dog as well as 196 inhabitants at two settlements on the waste disposal sites at the periphery of Cairo. Rattus norvegicus were positive in 55.4% for L. ictero-haemorrhagiae, pigs in 14.3% for L. pomona and in 3.6% for L. ictero-haemorrhagiae. 2 out of 12 donkeys were positive for L. pomona, 1 of them for L. pyrogenes and L. icterohaemorrhagiae as well, goats in 1.5% for L. grippotyphosa. Human sera reacted positively in 8.7% of the cases, 7.1% of which with L. bratislava, 1.0% with L. icterohaemorrhagiae and 0.5% with L. grippotyphosa and L. sejroe respectively. AD - National Reference Laboratory for Leptospirosis, Jihlava, CSSR. RO - M:MWS PMID- 2583498 LR - 900925 CU - 91 SO - Geogr Med Suppl 1989;3:141-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] [OMIM] UI - 90068993 AU - Lee HW AU - van der Groen G TI - Hemorrhagic fever with renal syndrome. LA - Eng MH - Animal MH - Hantavirus/isolation & purification MH - *Hemorrhagic Fever with Renal Syndrome/diagnosis/etiology/therapy MH - Human PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, ACADEMIC DA - 900108 DP - 1989 IS - 0079-645X TA - Prog Med Virol PG - 62-102 CY - SWITZERLAND VI - 36 JC - Q3E AA - Author EM - 9003 AB - Hantaviruses, the causative agents of HFRS, have become more widely recognized. Epidemiologic evidence indicates that these pathogens are distributed worldwide. People who come into close contact with infected rodents in urban, rural and laboratory environments are at particular risk. Transmission to man occurs mainly via the respiratory tract. The epidemiology of the hantaviruses is intimately linked to the ecology of their principal vertebrate hosts. Four distinct viruses are now recognized within the hantavirus genus and that number is likely to increase to six very soon; however, further investigations are necessary. Much more work is still needed before we fully understand the wide spectrum of clinical signs and symptoms of HFRS as well as the pathogenicity of the different viruses in the hantavirus genus of the Bunyaviridae family. HFRS is difficult to diagnose on clinical grounds alone and serological evidence is often needed. A fourfold rise in IgG antibody titer in a 1-week interval, and the presence of the IgM type of antibodies against hantaviruses are good evidence for an acute hantavirus infection. Physicians should be alert for HFRS each time they deal with patients with acute febrile flu-like illness, renal failure of unknown origin and sometimes hepatic dysfunction. Especially the mild form of HFRS is difficult to diagnose. Acute onset, headache, fever, increased serum creatinine, proteinuria and polyuria are signs and symptoms compatible with a mild form of HFRS. Differential diagnosis should be considered for the following diseases in the endemic areas of HFRS: acute renal failure, hemorrhagic scarlet fever, acute abdomen, leptospirosis, scrub typhus, murine typhus, spotted fevers, non-A, non-B hepatitis, Colorado tick fever, septicemia, dengue, heartstroke and DIC. Treatment of HFRS is mainly supportive. Recently, however, treatment of HFRS patients with ribavirin in China and Korea, within 7 days after onset of fever, resulted in a reduced mortality as well as shortened course of illness. RF - 168 PMID- 2573914 CU - 94 SO - Prog Med Virol 1989;36:62-102 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 90084140 AU - Azouvi P AU - Hostachy T AU - Desi M AU - Said G TI - [Acute and reversible axonal polyneuropathy in post-leptospirosis] LA - Fre MH - Acute Disease MH - Case Report MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*complications MH - Middle Age MH - Musculocutaneous Nerve/pathology MH - Peripheral Nervous System Diseases/*etiology/pathology PT - JOURNAL ARTICLE DA - 900123 DP - 1989 IS - 0035-3787 TA - Rev Neurol (Paris) PG - 805-7 SB - M CY - FRANCE IP - 11 VI - 145 JC - SU9 AA - Author EM - 9003 AB - A 53 year old woman presented, one month after an anicteric leptospirosis, an acute, asymmetrical, sensorimotor polyneuropathy involving the lower limbs. Electrophysiological study showed evidence of severe denervation, with normal motor nerve conduction velocities, indicating an axonal degeneration. Neuro-muscular biopsy showed signs of wallerian degeneration and perivascular infiltrates of epineural vessels. She received a corticosteroid therapy during 6 months and there was a nearly complete clinical recovery. AD - Service de Neurologie, Centre Hospitalier de Bicetre. PMID- 2556774 CU - 93 TT - Polyneuropathie axonale aigue et reversible dans les suites d'une leptospirose. EA - A SO - Rev Neurol (Paris) 1989;145(11):805-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 91362843 AU - Nuti M AU - Amaddeo D AU - Costa M AU - Cristaldi M AU - Ieradi LA AU - Montebarocci M TI - [Antibodies against Hantaan virus and Leptospira in subjects at risk in Rome] LA - Ita MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - English Abstract MH - Fluorescent Antibody Technique MH - Hantavirus/*immunology MH - Human MH - Leptospira/*immunology MH - Occupational Exposure MH - Prevalence MH - Risk Factors MH - Rodentia RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 911017 DP - 1989 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 284-8 SB - M CY - ITALY IP - 3 VI - 68 JC - AKG AA - Author EM - 9112 AB - A survey on the prevalence of Hantaan and leptospiral antibodies on mammalogists and rodent control personnel was performed. None of the 66 trappers studied (using IFI ) had detectable Hantaan antibody, while only 2 out of 20 mammalogists presented antibody at low titer (1:32). For leptospiral antibody the microagglutination test (MAT) using live leptospires as antigen was performed. 14 out of 66 trappers, or 21.2 per cent, had antibodies, at titer of 1:50 or more, to various leptospiral serovars: L.icterohaemorrhagiae in 12 cases, L.hardjo in 1 case, L.bratislava in 1 case. On the contrary, none of the mammalogists showed positivity for any of 16 serovars used. The environmental risk factors could justify the high prevalence of leptospiral antibodies in the field workers (trappers), while continuous laboratory contacts with rodents explain the presence of Hantaan virus antibodies in mammalogists . AD - Clinica Malattie Tropicali e Infettive, Universita La Sapienza, Roma. PMID- 2518821 CU - 91 TT - Anticorpi contro hantavirus e leptospire in soggetti a rischio in Roma. EA - A SO - Boll Ist Sieroter Milan 1989;68(3):284-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 91354662 AU - Gelosa L AU - Perone A TI - [Seroepidemiologic study of human leptospirosis in Lombardy] LA - Ita MH - Agglutinins/*analysis MH - Animal MH - Animals, Domestic/microbiology MH - Animals, Wild/microbiology MH - Antibodies, Bacterial/*blood MH - Comparative Study MH - Disease Reservoirs MH - English Abstract MH - Female MH - Human MH - Incidence MH - Italy/epidemiology MH - Leptospira/classification/*immunology MH - Leptospirosis/*epidemiology/immunology/microbiology MH - Male MH - Prevalence MH - Rural Population MH - Urban Population MH - Zoonoses RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 911010 DP - 1989 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 127-41 SB - M CY - ITALY IP - 2 VI - 68 JC - AKG AA - Author EM - 9112 AB - In 1987 a seroepidemiological research was performed to verify the prevalence of leptospira agglutinins on the urban and rural population of Milan, Bergamo and Mantova Provinces in Lombardia Region. Were controlled 150 subjects (75 males and 15 females) in Milan town, 58 (49 males and 9 females) in municipalities of Bergamo Province, and 68 (55 males and 13 females) of Mantova Province. La prevalence of leptospira agglutinins in exposed subjects was 14.3% and in unexposed subjects 8.6%. In the females was noted a significative higher prevalence of agglutinins (14.4%) than in males (9.5%), especially in the females exposed (36.3%) than in females unexposed (9.6%). The leptospira serovars most interested were L. sejroe (15.9%), L. poi (13.6%), L. bratislava, L. canicola and L. Zanoni (9.1%). The sera tested proved reactivity of 56.8% also against two or three different serovars of pathogenic leptospira and prevalence of 13.6% of coagglutinins against nonpathogenic L. patoc serovar. AD - Istituto di Microbiologia dell'Universita di Milano. PMID- 2491297 CU - 91 TT - Indagine sieroepidemiologica sulla leptospirosi umana in Lombardia. EA - A SO - Boll Ist Sieroter Milan 1989;68(2):127-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 91354639 AU - Benzi Cipelli R AU - Gorini G AU - Caligaris S AU - Lanzarini P AU - Milano F AU - Orsolini P AU - Filice G TI - [In vitro sensitivity of 3 strains of Leptospira interrogans to 3 different antibiotics] LA - Ita MH - Comparative Study MH - Drug Resistance, Microbial MH - English Abstract MH - Erythromycin/*pharmacology MH - Josamycin/*pharmacology MH - Leptospira interrogans/classification/*drug effects/ultrastructure MH - Penicillin Resistance MH - Penicillins/*pharmacology MH - Species Specificity RN - 0 (Penicillins) RN - 114-07-8 (Erythromycin) RN - 16846-24-5 (Josamycin) PT - JOURNAL ARTICLE DA - 911007 DP - 1989 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 17-23 SB - M CY - ITALY IP - 1 VI - 68 JC - AKG AA - Author EM - 9112 AB - Leptospirosis, anthropo-zoonosis ubiquitously widespread, is a social and economic problem still to be solved. The experimental and therapeutic employment of many antibiotics has largely been tested "in vitro" and "in vivo". In the following research we tried to evaluate, by experimental "in vitro" method, the sensitivity difference of three serovar strains of Leptospira interrogans to two macrolides, Erythromycin and Josamycin, compared with Penicillin. From standard cultures, previously treated with serial dilution of these antibiotics, the MIC and MSC, as quantitative parameters, have been stated. For the qualitative evaluation of the damages induced at ultrastructural level by the drug activity. Electron Microscopy investigations were performed on specimens from cultures treated for 6 hr with twice and tenfold the MSC. The present research confirms the good sterilizing efficaciousness "in vitro" of the tested macrolides (MSC less than 1 mcg/ml) and their different activity pathway. AD - Istituto di Clinica delle Malattie Infettive, Universita di Pavia, IRCCS Ospedale Policlinico San Matteo. PMID- 2491282 CU - 92 TT - Suscettibilita in vitro di tre ceppi di Leptospira interrogans a tre differenti antibiotici. EA - A SO - Boll Ist Sieroter Milan 1989;68(1):17-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 91018553 AU - Lumlertgul D AU - Hutdagoon P AU - Sirivanichai C AU - Keoplung M AU - Wongmekiat O AU - Nitsin S AU - Sangchun G TI - Beneficial effect of intrarenal verapamil in human acute renal failure. LA - Eng MH - Adult MH - Aged MH - Aged, 80 and over MH - Comparative Study MH - Drug Therapy, Combination MH - Female MH - Furosemide/administration & dosage/*therapeutic use MH - Human MH - Infusions, Intra-Arterial MH - Infusions, Intravenous MH - Kidney Failure, Acute/*drug therapy MH - Male MH - Support, Non-U.S. Gov't MH - Verapamil/administration & dosage/*therapeutic use RN - 52-53-9 (Verapamil) RN - 54-31-9 (Furosemide) PT - JOURNAL ARTICLE DA - 901119 DP - 1989-90 IS - 0886-022X TA - Ren Fail PG - 201-8 SB - M CY - UNITED STATES IP - 4 VI - 11 JC - RCG AA - Author EM - 9101 AB - Cellular Ca2+ influx during the reperfusion period after an ischemic insult has been proposed to be a crucial pathogenetic factor in the development of experimental acute renal failure (ARF). The present study, therefore, examined the potential beneficial effect of intrarenal verapamil, a calcium entry blocking agent, on ARF in patients. Twelve patients were enrolled in the study. Six ARF patients (experimental group)--ARF caused by malaria (4 patients) and leptospirosis (2 patients)--had a catheter placed in their renal artery; verapamil was infused at 100 micrograms/min for 3 h and intravenous furosemide, 0.8 mg/kg/h x 24 h was also administered. Another six ARF patients (control group)--ARF caused by malaria (5 patients) and leptospirosis (1 patient)--were treated with intravenous furosemide alone. Baseline renal function was comparable in both groups; GFR (3.16 +/- 3.24 vs 0.7 +/- 1.5 mL/min, NS), serum creatinine (Scr), (9.1 +/- 2.1 vs 11.3 +/- 2.2 mg/dL, NS), and urine volume (V) (41.79 +/- 4.77 vs 34.54 +/- 13.52 mL/h, NS), were comparable in the experimental and control groups. Twenty-four hours posttreatment, the increment of GFR (9.66 +/- 4.25 vs 1.32 +/- 0.50 mL/min, P less than .02) and V (181.8 +/- 61.7 vs 79 +/- 18 mL/h, P less than .04), were significantly greater in the experimental group as compared to the control group. The course of ARF was also shorter in the experimental group (6.5 +/- 2.1 vs 13 +/- 1.1 days, P less than .05), who also required less dialysis. Thus, combination of a renal arterial infusion of verapamil and intravenous furosemide significantly improves the renal function in tropical ARF as compared to intravenous furosemide alone. AD - Department of Medicine, Faculty of Medicine, Chiang Mai University, Thailand. PMID- 2485483 SO - Ren Fail 1989-90;11(4):201-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 90166419 AU - Mete R AU - Fichera R TI - [A case of leptospirosis in an agrarian community] LA - Ita MH - Aged MH - Agricultural Workers' Diseases/etiology MH - Animal MH - Case Report MH - Cattle MH - Cattle Diseases/transmission MH - Dog Diseases/transmission MH - Dogs MH - English Abstract MH - Human MH - Italy MH - Leptospirosis/*transmission/veterinary MH - Male MH - Swine MH - Swine Diseases/transmission MH - Zoonoses PT - JOURNAL ARTICLE DA - 900412 DP - 1989 Jan-Apr IS - 1120-9135 TA - Ann Ig PG - 219-22 CY - ITALY IP - 1-2 VI - 1 JC - AND AA - Author EM - 9006 AB - A mortal case of leptosprosis happened in a little agricultural community situated in a country town in the south Lazio Region, and in consequence of that the Local Health Unit originated a series of epidemiological investigation and preventive treatments. Serological tests were effectuated both on the residents of the interested area and on animals of the farm. These serological tests gave positive results for four inhabitants and eight animals. The agricultural community were subjected to a chemoprophylaxis. No new cases of disease have been found. The drinking water was analyzed because the water supplied came from unprotected wells. The tests gave unfavorable results for the presence of fecal streptococci. It wasn't possible to effect specific tests for the research of leptospira, because it was difficult to find suitably equipped laboratory. As a result of these tests it was decided to apply preventive treatments on a permanent basis on the farm in question. The fact that the serodiagnosis showed the same kind of leptospira in both men and animal, suggested once again the problem of transmission between animals and men and the need for adequate measures of profilaxis. Also the need to cover exposed agricultural work men with an adequate insurance. Great interest was shown in the correct intervention of the operators of Public Hygiene Service and Veterinary Services. It's essential to coordinate the activity of the two services for an effective intervention in these si milar cases, both during the phases of epidemiological research and prevention. Intention of this work is to furnish a possible operative procedure for situations of this kind. PMID- 2483068 CU - 95 TT - Caso di leptospirosi in comunita agricola. EA - A SO - Ann Ig 1989 Jan-Apr;1(1-2):219-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 89371109 AU - Panasiak W AU - Wleklik M AU - Oraczewska A AU - Luczak M TI - Serological studies of haemorrhagic fever with renal syndrome (HFRS) in Poland. Preliminary report. LA - Eng MH - Animal MH - Antibodies, Viral/*analysis MH - Fluorescent Antibody Technique MH - Hantavirus/*immunology MH - Hemorrhagic Fever with Renal Syndrome/epidemiology MH - Human MH - Mice MH - Poland MH - Rats MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 891003 DP - 1989 IS - 0001-6195 TA - Acta Microbiol Pol PG - 63-7 SB - M CY - POLAND IP - 1 VI - 38 JC - 17I AA - Author EM - 8912 AB - Serological studies of Hantaan virus infections among--blood donors (control group)--patients: chronic dialysed, leptospirosis suspected, hospitalised for various diseases,--risk group population: farmers, laboratory staff (contact with laboratory animals), as well as laboratory and wild animals (rodents) were carried out. Surveys were done by the indirect immunofluorescent antibody (IFA) procedure with 5 Hantaan virus strains as antigens. AD - Department of Virology, Medical Academy, Warsaw, Poland. PMID- 2476002 CU - 95 SO - Acta Microbiol Pol 1989;38(1):63-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 89364348 AU - Fukunaga M AU - Mifuchi I TI - The number of large ribosomal RNA genes in Leptospira interrogans and Leptospira biflexa. LA - Eng MH - Blotting, Southern MH - Cloning, Molecular MH - DNA Probes MH - DNA, Bacterial/biosynthesis/genetics MH - Electrophoresis, Agar Gel MH - *Genes, Bacterial MH - Leptospira interrogans/classification/*genetics MH - RNA, Bacterial/*genetics MH - RNA, Ribosomal/*genetics MH - RNA, Ribosomal, 23S/*genetics MH - Species Specificity RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) RN - 0 (RNA, Bacterial) RN - 0 (RNA, Ribosomal) RN - 0 (RNA, Ribosomal, 23S) PT - JOURNAL ARTICLE DA - 891011 DP - 1989 IS - 0385-5600 TA - Microbiol Immunol PG - 459-66 SB - M CY - JAPAN IP - 6 VI - 33 JC - MX7 AA - Author EM - 8912 AB - We determined the number of large ribosomal RNA genes in five strains of Leptospira by hybridization of 15 restriction endonuclease digests of genomic DNA to the [32P]-labeled fragment of 23s rRNA gene. Almost all the restriction gels gave two radioactive bands. The conclusion from these results is that there are at least two rRNA genes in these leptospiral strains. Furthermore, the hybridization patterns of L. icterohaemorrhagiae strains Ictero No. I and RGA are almost identical. The number of rRNA genes and taxonomic relationships of these leptospires were discussed. AD - Faculty of Pharmacy and Pharmaceutical Science, University of Fukuyama, Hiroshima. PMID- 2475749 CU - 95 SO - Microbiol Immunol 1989;33(6):459-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 89237102 AU - Podkorytov IuI TI - [A method of improving darkfield microscopy] LA - Rus MH - *Bacteriological Techniques MH - Leptospira/classification MH - Microscopy/*methods PT - JOURNAL ARTICLE DA - 890619 DP - 1989 IS - 0023-6748 TA - Lab Delo PG - 74-5 CY - USSR IP - 3 JC - KYU EM - 8908 PMID- 2469854 CU - 95 TT - Sposob sovershenstvovaniia temnopol'noi mikroskopii. SO - Lab Delo 1989;(3):74-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 89237076 AU - Mel'nitskaia EV AU - Kondratenko VN TI - [Use of the coagglutination reaction for typing Leptospira cultures] LA - Rus MH - Agglutination Tests MH - English Abstract MH - Leptospira/*classification MH - Reagent Kits, Diagnostic MH - Serotyping/*methods RN - 0 (Reagent Kits, Diagnostic) PT - JOURNAL ARTICLE DA - 890619 DP - 1989 IS - 0023-6748 TA - Lab Delo PG - 11-3 CY - USSR IP - 3 JC - KYU AA - Author EM - 8908 AB - The coagglutination test has been employed for the serologic typing of Leptospira cultures. A set of diagnostic agents with a maximum kit of anti-Leptospira sera of various serogroups has been prepared on the basis of a 10% suspension of formalin-treated Cowan 1 staphylococcus strain. To prepare the diagnostic agent, 0.1 portion of the serum and 9 portions of phosphate buffer solution, pH 7.2 should be added to 1 portion of a 10% staphylococcal suspension. 1% staphylococcal suspension has been prepared for control. The diagnosticum and the culture to type (0.01 ml each) have been mixed on the slides; the control test has been carried out with 1% non-sensitized staphylococcal suspension. The test has been read by microscopy in the dark visual field after the slides' 15 min exposure in a humid chamber. Typing of 17 Leptospira cultures of known serologic groups has yielded positive responses with the homologous diagnosticums only; no cross reactions have been recorded. The coagglutination test may be used for the rapid differentiation of mixed Leptospira cultures belonging to different serologic groups. PMID- 2469828 CU - 95 TT - Ispol'zovanie reaktsii koaggliutinatsii dlia tipirovaniia kul'tur leptospir. EA - A SO - Lab Delo 1989;(3):11-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 89079308 AU - Schaible UE AU - Kramer MD AU - Justus CW AU - Museteanu C AU - Simon MM TI - Demonstration of antigen-specific T cells and histopathological alterations in mice experimentally inoculated with Borrelia burgdorferi. LA - Eng MH - Animal MH - Antigens, Bacterial/*immunology MH - Borrelia/immunology MH - Cells, Cultured MH - Epitopes/*immunology MH - Female MH - Hypersensitivity, Delayed/immunology MH - Kidney/pathology MH - Lung/pathology MH - Lyme Disease/*immunology/pathology MH - Lymphocyte Transformation MH - Male MH - Mice MH - Mice, Inbred AKR MH - Mice, Inbred BALB C MH - Mice, Inbred C57BL MH - Myocardium/pathology MH - Support, Non-U.S. Gov't MH - T-Lymphocytes/*immunology RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 890203 DP - 1989 Jan IS - 0019-9567 TA - Infect Immun PG - 41-7 SB - M SB - X CY - UNITED STATES IP - 1 VI - 57 JC - GO7 AA - Author EM - 8904 AB - Antigen-specific T-cell responses and histopathological changes were studied in mice experimentally inoculated with Borrelia burgdorferi B31. Inbred mice with different H-2 haplotypes and/or different genetic backgrounds were inoculated with B. burgdorferi organisms and tested for antigen-specific T-cell responses in vivo (delayed-type hypersensitivity [DTH]) and in vitro (T-cell proliferation). Comparable DTH responses were found after inoculation with either inactivated (in the presence of adjuvants) or viable microorganisms in all mouse strains, except BALB/c, irrespective of the H-2 haplotype (b, d, k, or s) tested and the sex of the animals. Moreover, in mice presensitized to B. burgdorferi, DTH responses could be induced only with antigen preparations derived from the corresponding strain but not with those obtained from either related spirochetes such as Treponema phagedenis and Leptospira interrogans or unrelated bacteria such as Mycobacterium tuberculosis. T cells isolated from lymph nodes or spleens of mice previously sensitized to B. burgdorferi but not those from naive mice could be induced for antigen-specific proliferation in vitro, as revealed by [3H]thymidine incorporation. Histopathological examination of mice inoculated with viable B. burgdorferi organisms revealed significant perivascular infiltrates consisting mainly of mononuclear and a few polymorphonuclear leukocytes in different organs (brain, heart, lungs, liver, and kidneys) and the appearance of giant multinucleated cells within the spleen similar to those found in human skin specimens of patients suffering from cutaneous manifestations of Lyme disease. Our findings suggest that mice are a suitable animal model with which to study the immune response to B. burgdorferi and the pathogenesis of Lyme disease. AD - Max-Planck-Institut fur Immunbiologie, Freiburg, Federal Republic of Germany. PMID- 2462540 CU - 95 SO - Infect Immun 1989 Jan;57(1):41-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 89243388 AU - Zhang FZ AU - Zhou CY AU - Wang XY TI - [A new Leptospiral serovar in the hebdomadis serogroup] LA - Chi MH - English Abstract MH - Human MH - Leptospira/*classification/isolation & purification MH - Nomenclature MH - Serotyping MH - Weil's Disease/microbiology PT - JOURNAL ARTICLE DA - 890615 DP - 1988 Dec IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 367-70 CY - CHINA IP - 4 VI - 28 JC - XNA EM - 8908 PMID- 3247720 EA - A SO - Wei Sheng Wu Hsueh Pao 1988 Dec;28(4):367-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 89187082 AU - Lane EM AU - Ramaley RF AU - Miller NG TI - Variation in the hemolytic activity of Leptospira interrogans serovar canicola. LA - Eng MH - Animal MH - Comparative Study MH - Culture Media MH - Dogs MH - Guinea Pigs MH - Hamsters MH - Hemolysins/biosynthesis/isolation & purification/*metabolism MH - Human MH - Leptospira interrogans/*metabolism MH - Mice MH - Rabbits RN - 0 (Culture Media) RN - 0 (Hemolysins) PT - JOURNAL ARTICLE DA - 890511 DP - 1988 Dec IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 629-32 SB - M CY - THAILAND IP - 4 VI - 19 JC - UVN AA - Author EM - 8907 AB - Leptospira interrogans serovar canicola strain moulton was grown to a high cell density in a protein-free medium with hemin. The hemolysin produced in this culture system showed a greatly expanded spectrum of hemolysis as compared to previous reports of leptospiral hemolysin produced in a more traditional culture system containing serum. AD - Department of Medical Microbiology, University of Nebraska College of Medicine, Omaha 68105. PMID- 3238474 CU - 91 SO - Southeast Asian J Trop Med Public Health 1988 Dec;19(4):629-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 89155732 AU - Zuerner RL AU - Bolin CA TI - Repetitive sequence element cloned from Leptospira interrogans serovar hardjo type hardjo-bovis provides a sensitive diagnostic probe for bovine leptospirosis. LA - Eng MH - Animal MH - Blotting, Southern MH - Cattle MH - Cattle Diseases/*diagnosis/urine MH - Cloning, Molecular MH - DNA Probes MH - DNA, Bacterial/*genetics MH - Leptospira interrogans/classification/*genetics MH - Repetitive Sequences, Nucleic Acid MH - Restriction Mapping MH - Serotyping MH - Weil's Disease/diagnosis/urine/*veterinary RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 890420 DP - 1988 Dec IS - 0095-1137 TA - J Clin Microbiol PG - 2495-500 SB - M CY - UNITED STATES IP - 12 VI - 26 JC - HSH AA - Author EM - 8906 AB - A repetitive sequence element was cloned from the primary etiological agent causing bovine leptospirosis in North America, Leptospira interrogans serovar hardjo type hardjo-bovis. This element was used to design a sensitive diagnostic probe which distinguishes hardjo-bovis from other pathogenic leptospires which commonly infect domestic animals in North America and discriminates between hardjo-bovis and the reference strain for serovar hardjo, hardjoprajitno. By using this probe, it was possible to identify infected cattle shedding hardjo- bovis in their urine. This is the first practical demonstration of a cloned DNA probe for leptospirosis, and it provides a sensitive method for studying the transmission and pathogenesis of L. interrogans infections. Control measures for L. interrogans infections may now be improved by rapidly and efficiently identifying infected animals. AD - National Animal Disease Center, U.S. Department of Agriculture, Ames, Iowa 50010. PMID- 3230128 CU - 92 SO - J Clin Microbiol 1988 Dec;26(12):2495-500 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 89117570 AU - Brem S AU - Kopp H AU - Meyer P AU - Hollmann P TI - [The first isolation of Leptospira serovar hardjo in West Germany] LA - Ger MH - Animal MH - Bacteriuria/microbiology MH - Cattle MH - Cattle Diseases/*epidemiology MH - English Abstract MH - Germany, West MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 890224 DP - 1988 Dec 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 419-21 CY - GERMANY, WEST IP - 12 VI - 101 JC - 9Q8 EM - 8905 PMID- 3219120 TT - Erste Isolation von Leptospira Serovar hardjo in der Bundesrepublik Deutschland. EA - A SO - Berl Munch Tierarztl Wochenschr 1988 Dec 1;101(12):419-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 89117569 AU - Brem S AU - Schreyer K TI - [The occurrence of leptospiral antibodies in bovine sera from Bavaria] LA - Ger MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*epidemiology MH - English Abstract MH - Germany, West MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890224 DP - 1988 Dec 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 416-9 CY - GERMANY, WEST IP - 12 VI - 101 JC - 9Q8 EM - 8905 PMID- 3219119 CU - 91 TT - Untersuchungen an Rinderseren aus Bayern uber das Auftreten von Leptospirenantikorpern. EA - A SO - Berl Munch Tierarztl Wochenschr 1988 Dec 1;101(12):416-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 89224867 AU - Chernukha IuG AU - Evdokimova OA AU - Chekhovich AV AU - Anan'ina IuV TI - [The noncorrespondence of the geographic ranges of the host and the causative agent] LA - Rus MH - Animal MH - Carrier State/microbiology/veterinary MH - *Disease Reservoirs MH - *Disease Vectors MH - Ecology MH - English Abstract MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/microbiology/veterinary MH - Muridae/*microbiology MH - Russia MH - Serotyping PT - JOURNAL ARTICLE DA - 890526 DP - 1988 Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 70-2 SB - M CY - USSR IP - 12 JC - Y9O AA - Author EM - 8908 AB - For the first time the experimental and field studies of Leptospira infections, carried out over the period of 6 years, have revealed that the habitat of striped field mice (Apodemus agrarius Pallas 1778) serving as a host for Leptospira pomona, serovar mozdok, is much wider than the habitat of the infective agent proper. The presence of an animal species highly sensitive to a definite leptospiral serovar and serving as its reservoir at a given locality cannot be regarded as a proof of the presence of the epizootic process without bacteriological confirmation. But, in the absence of homologous Leptospira carriage, intensive leptospiral seroconversion can be attributed to a population other than that of the host. PMID- 2977463 CU - 92 TT - O nesootvetstvii arealov khoziaina i vozbuditela. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1988 Dec;(12):70-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 89079510 AU - Songer JG AU - Thiermann AB TI - Leptospirosis. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/microbiology/*transmission MH - Human MH - Leptospirosis/transmission/*veterinary MH - Rodent Diseases/microbiology/*transmission MH - Rodentia MH - Zoonoses/*transmission PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 890209 DP - 1988 Nov 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1250-4 SB - M CY - UNITED STATES IP - 10 VI - 193 JC - HAV EM - 8904 AD - Department of Veterinary Science, College of Agriculture, University of Arizona, Tucson 85721. RF - 46 PMID- 3060453 CU - 90 SO - J Am Vet Med Assoc 1988 Nov 15;193(10):1250-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 89040200 AU - Barinaga M TI - US sea lions join casualties [news] LA - Eng MH - Animal MH - California MH - Leptospirosis/veterinary MH - *Pinnipedia MH - *Seals MH - Seizures/*veterinary MH - Water Pollution PT - NEWS DA - 881130 DP - 1988 Nov 3 IS - 0028-0836 TA - Nature PG - 8 SB - M SB - X CY - ENGLAND IP - 6194 VI - 336 JC - NSC EM - 8902 PMID- 3185724 CU - 91 SO - Nature 1988 Nov 3;336(6194):8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 89175386 AU - Masuzawa T AU - Kumagai M AU - Shimizu T AU - Yanagihara Y TI - Classification of Leptospira interrogans serovar lai strain 017 by using monoclonal antibodies. LA - Eng MH - Antibodies, Monoclonal/*diagnostic use MH - Antigens, Bacterial/analysis MH - Enzyme-Linked Immunosorbent Assay MH - Leptospira/*classification/immunology MH - Serotyping MH - Species Specificity RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 890510 DP - 1988 Nov IS - 0095-1137 TA - J Clin Microbiol PG - 2332-7 SB - M CY - UNITED STATES IP - 11 VI - 26 JC - HSH AA - Author EM - 8907 AB - Leptospira interrogans serovar lai was identified in China in 1966 as a new serovar of the icterohaemorrhagiae serogroup by cross-absorption tests. In this study, we established three hybridoma cell lines producing monoclonal antibodies (MAbs) of the immunoglobulin G3 subclass (LW1, LW2, and LW3) and of the immunoglobulin M class (LW4a) against serovar lai strain 017 by the cell fusion technique. Immunological reactivities of the MAbs were determined by the microscopic agglutination test, enzyme-linked immunosorbent assay (ELISA), and indirect immunofluorescence assay. MAbs LW1 and LW3 agglutinated cells of serovars lai, birkini, and gem of serogroup icterohaemorrhagiae. LW2 agglutinated various serovars of serogroup icterohaemorrhagiae, except for serovar tonkini. LW4a reacted positively with various Leptospira species, including a new species, Leptospira parva, in the ELISA and indirect immunofluorescence assay. However, LW4a did not react with Leptonema illini 3055. The results of an inhibition ELISA with heated outer envelope (OE) or periodate- oxidized OE suggested that these MAbs recognize a carbohydrate moiety of the OE as the antigenic determinant. AD - Department of Microbiology, School of Pharmaceutical Sciences, University of Shizuoka, Japan. PMID- 3235658 CU - 91 SO - J Clin Microbiol 1988 Nov;26(11):2332-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 89124558 AU - Sada E TI - [Analysis of immunological characteristics of serogroup icterohaemorrhagiae using monoclonal antibodies] LA - Jpn MH - Animal MH - Antibodies, Monoclonal/*diagnostic use/immunology MH - Antigen-Antibody Reactions MH - English Abstract MH - Immunoblotting MH - Leptospira interrogans/classification/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 890323 DP - 1988 Nov IS - 0387-5911 TA - Kansenshogaku Zasshi PG - 944-58 CY - JAPAN IP - 11 VI - 62 JC - IJR EM - 8905 PMID- 3146606 CU - 91 EA - A SO - Kansenshogaku Zasshi 1988 Nov;62(11):944-58 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 89145789 AU - Pertuiset E AU - Fen Chong M AU - Duval G AU - Genin R TI - [Clinical aspects and prognostic factors of icterohemorrhagic leptospirosis in adults. Apropos of 249 cases in La Reunion] LA - Fre MH - Adult MH - Cause of Death MH - English Abstract MH - Human MH - Indian Ocean Islands MH - Microcomputers MH - Middle Age MH - Prognosis MH - Retrospective Studies MH - Risk Factors MH - Weil's Disease/complications/*mortality PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 890328 DP - 1988 Nov-Dec IS - 0248-8663 TA - Rev Med Interne PG - 487-93 SB - M CY - FRANCE IP - 5 VI - 9 JC - SGJ AA - Author EM - 8906 AB - Human leptospirosis of the classical and severe icterohemorrhagic type, usually due to the L. icterohaemorrhagiae serogroup, is frequent in La Reunion. In a retrospective study conducted between 1980 and 1984 in 249 adult patients, the mortality rate was 13 p. 100. Our data and those found in the literature indicate that the main cause of death is pneumopathy, followed by profuse haemorrhages, arrhythmias and cardiovascular collapse. Acute renal failure is common and often severe; it facilitates gastrointestinal bleeding and is of poor prognosis, particularly in patients with prolonged anuria, a possible cause of lethal hyperkalaemia. Other factors of unfavourable outcome have been demonstrated statistically; they include disturbances of consciousness, hypoprothrombinaemia, epigastric muscle rigidity, hyperleukocytosis, thrombocytopenia, high aspartate aminotransferase levels and chronic alcoholism. At the moment, pulmonary, cardiac and haemorrhagic complications concur with renal failure to darken the prognosis of these severe forms of leptospirosis. AD - Service de nephrologie hemodialyse, CHD Felix Guyon, Saint-Denis, la Reunion. RF - 47 PMID- 3067293 CU - 90 TT - Aspects cliniques et facteurs pronostiques des leptospiroses ictero- hemorragiques de l'adulte. A propos de 249 cas observes a la Reunion. EA - A SO - Rev Med Interne 1988 Nov-Dec;9(5):487-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 89115699 AU - Volina EG AU - Arimitsu Y AU - Kobayashi S AU - Kiktenko VS AU - Tkachenko EA TI - [Use of microcapsular leptospiral antigens for detecting specific antibodies] LA - Rus MH - Adsorption MH - Agglutination Tests/methods MH - Animal MH - Antibodies, Bacterial/*analysis MH - *Antibody Specificity MH - Antigens, Bacterial/*immunology MH - Capsules MH - Comparative Study MH - English Abstract MH - Evaluation Studies MH - Guinea Pigs MH - Immunization MH - Immunoenzyme Techniques MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Rabbits MH - Time Factors RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Capsules) PT - JOURNAL ARTICLE DA - 890306 DP - 1988 Nov IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 90-4 SB - M CY - USSR IP - 11 JC - Y9O AA - Author EM - 8905 AB - The sensitivity of microcapsular leptospiral antigens, produced by Japan Lyophilization Laboratory and intended for use in tests for the detection of antibodies to leptospires in the sera of experimentally immunized laboratory animals, were studied. The comparative study of the microcapsular agglutination (MCA) test and other serological tests, such as the microagglutination (MA) test and the indirect enzyme immunoassay (EIA), was made. The leptospiral antigens under study were found to actively react with serospecific and group-specific antibodies. In infected guinea pigs and rabbits specific antibodies could be detected from days 3-4 in the MCA test and only from days 5-7 in the MA test. The average antibody level determined by titration in the MCA test was 3.3 times higher and in indirect EIA, 4.3 times higher than that determined by titration in the MA test. These data make it possible to recommend the use of microcapsular leptospiral antigens for the early diagnosis of leptospirosis. PMID- 3064517 CU - 91 TT - Ispol'zovanie leptospiroznykh mikrokapsul'nykh antigenov dlia vyiavleniia spetsificheskikh antitel. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1988 Nov;(11):90-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 89084306 AU - Everard CO AU - Everard JD TI - Mongoose rabies. LA - Eng MH - Animal MH - Carnivora/*microbiology MH - *Disease Vectors MH - Immunity, Natural MH - Mongoose/immunology/*microbiology MH - Rabies/immunology/prevention & control/transmission/*veterinary PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 890209 DP - 1988 Nov-Dec IS - 0162-0886 TA - Rev Infect Dis PG - S610-4 SB - M CY - UNITED STATES VI - 10 Suppl 4 JC - SXN AA - Author EM - 8904 AB - Mongooses are indigenous to Africa and Asia and have been introduced elsewhere. In Cuba, Puerto Rico, Grenada, and South Africa they are the major reservoir and vector of rabies. Elsewhere, sporadic cases of mongoose rabies are reported, but dog rabies can mask their importance. Population density probably determines the importance of the mongoose as a reservoir of rabies. In Grenada during a 4-year period, nearly 30% (and in some areas greater than 50%) of mongooses were found to have rabies serum neutralizing antibodies. The annual proportions of mongooses that were serum antibody-positive and virus-positive, respectively, were inversely related. Natural immunity in mongooses probably lasts for life. In contrast with foxes, in mongooses immunity is an important factor in the epizootiology of rabies. Inoculation of mongooses with Evelyn-Rokitnicki-Abelseth (ERA) vaccine induced a good immunologic response and augurs well for the success of vaccination in the field. The effects of wildlife vaccination on animal populations with high levels of natural immunity need to be investigated before costly campaigns are started. AD - Medical Research Council, Leptospira Laboratory, Bridgetown, Barbados. RF - 14 PMID- 3060954 CU - 90 SO - Rev Infect Dis 1988 Nov-Dec;10 Suppl 4:S610-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 89060471 AU - Lee M AU - Lambros C TI - The ELISA-U: an enzyme-linked immunosorbent assay using urease as the enzyme marker for rapid detection of Plasmodium falciparum antibody in human serum. LA - Eng MH - Animal MH - Antibodies, Protozoan/*analysis MH - Comparative Study MH - Cross Reactions MH - *Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique MH - Human MH - Plasmodium falciparum/*immunology MH - Predictive Value of Tests MH - *Urease RN - EC 3.5.1.5 (Urease) RN - 0 (Antibodies, Protozoan) PT - JOURNAL ARTICLE DA - 881230 DP - 1988 Nov IS - 0002-9637 TA - Am J Trop Med Hyg PG - 421-6 SB - A SB - M CY - UNITED STATES IP - 5 VI - 39 JC - 3ZQ AA - Author EM - 8903 AB - A visual, enzyme-linked immunosorbent assay using urease (ELISA-U) as the enzyme marker was adapted for rapid detection of antibody against Plasmodium falciparum. Flat-bottom, 96-well microtiter plates were coated with P. falciparum soluble antigen obtained by saponin and NP-40 treatment of parasite cultures. Antibody was detected by successive incubations with test sera, urease-conjugated rabbit-human antibody, and urease substrate. Reactive sera developed a definite and easily visualized purple color. Sera from patients with single infections of P. vivax or P. ovale were unreactive. No cross-reactivity was noted with sera from patients with rheumatoid arthritis, filariasis, amebiasis, schistosomiasis, dengue, scrub typhus, leptospirosis, or toxoplasmosis. The procedure can be performed at room temperature and completed within 1 hr. The sensitivity of the assay is comparable to that of the indirect fluorescent antibody test at all but the lowest dilutions tested. AD - Malaria Research Group, U.S. Army Medical Research Unit, Kuala Lumpur, Malaysia. PMID- 3057927 CU - 91 SO - Am J Trop Med Hyg 1988 Nov;39(5):421-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 89245398 AU - Weber AF AU - Meiske JC AU - Haggard DL AU - Sorensen DK AU - Domagala AM AU - Flaum AM TI - Failure to demonstrate transmission of enzootic bovine leukemia virus infection from cows to sheep by use of common injection needles. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*transmission MH - Equipment Contamination MH - Injections, Intramuscular/adverse effects/veterinary MH - Leukemia Virus, Bovine MH - Lymphocytes/microbiology MH - *Needles MH - Random Allocation MH - Sheep MH - Sheep Diseases/*transmission MH - Support, Non-U.S. Gov't MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 890616 DP - 1988 Nov IS - 0002-9645 TA - Am J Vet Res PG - 1814-6 SB - M CY - UNITED STATES IP - 11 VI - 49 JC - 40C AA - Author EM - 8908 AB - Four bovine leukemia virus (BLV)-seropositive and 2 BLV-seronegative cows were used as donors in a study to provide evidence whether IM injection with common needles is a means of spreading bovine leukemia. Sheep were used as recipients. Of the 4 BLV-seropositive cows, 2 had high virus expression (VE; 43% and 28% of their lymphocyte thin sections had associated BLV-particles), whereas the other 2 cows did not have observed VE. After each of the 4 cows was given an injection of a 5-antigen Leptospira bacterin, a BLV-seronegative sheep was immediately given an injection of the same bacterin with the same needle. None of these sheep seroconverted, nor did either of 2 sheep given only the bacterin (with a previously unused needle). Sheep inoculated IM with 0.2 ml of whole blood from both of the cows with high VE and from 1 of the 2 BLV-seropositive cows that did not have observed VE did seroconvert. In contrast, the sheep inoculated with 0.2 ml of blood from the remaining BLV-seropositive (0% VE) cow and from the 2 BLV-seronegative cows remained seronegative. These results were interpreted to indicate that the quantity of infective lymphocytes passed during injection with common needles is too small to induce infection. AD - Department of Veterinary Biology, University of Minnesota, St. Paul 55108. PMID- 2854706 CU - 93 SO - Am J Vet Res 1988 Nov;49(11):1814-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 89115581 AU - Cinco M AU - Banfi E AU - Panfili E TI - Leptospiral lipopolysaccharide presence in the outer envelope: electrophoretic evidence and immunological specificity. LA - Eng MH - Antibodies, Monoclonal/immunology MH - Antibody Specificity MH - Cell Membrane/analysis MH - Electrophoresis, Polyacrylamide Gel MH - Epitopes MH - Leptospira interrogans/*analysis/classification/ultrastructure MH - Lipopolysaccharides/*analysis/immunology MH - Precipitin Tests RN - 0 (Antibodies, Monoclonal) RN - 0 (Epitopes) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 890228 DP - 1988 Nov IS - 0176-6724 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 277-83 SB - M CY - GERMANY, WEST IP - 3 VI - 269 JC - Y55 AA - Author EM - 8905 AB - Purified preparations of lipopolysaccharides (LPS) extracted from two different strains of Leptospira interrogans have been electrophoretically analyzed in order to determine their location at the level of outer envelope (OE). Evidence has been collected for the presence of some LPS fractions in the OE, suggesting that a part of this molecule is embedded in the membrane structure. The serological specificity of the LPS has been in addition tested by means of monoclonal antiserovar antibodies (Moabs); the results indicated that the LPS structure is endowed of the immunodeterminants of the serovar. The remarkable relevance of this finding for the Leptospira taxonomy is discussed. AD - Istituto di Microbiologia, University of Trieste, Italy. PMID- 2464258 CU - 95 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1988 Nov;269(3):277-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 90018967 AU - Riedemann S AU - Zamora J TI - [Leptospirosis. Zoonosis without transcendence in Chile?] LA - Spa MH - Animal MH - Animals, Domestic MH - Chile MH - Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/transmission MH - Muridae MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 891101 DP - 1988 Oct IS - 0034-9887 TA - Rev Med Chil PG - 1066-9 CY - CHILE IP - 10 VI - 116 JC - SHD EM - 9001 PMID- 3267884 TT - Leptospirosis. Zoonosis sin trascendencia en Chile? EA - A SO - Rev Med Chil 1988 Oct;116(10):1066-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 89048895 AU - Dussarat GV AU - Cointet F AU - Capdevielle P AU - Le Bris H AU - Brethes B TI - [Cardiac manifestations in leptospirosis. Apropos of 15 cases observed in New Caledonia] LA - Fre MH - Adult MH - Aged MH - English Abstract MH - Female MH - Heart Diseases/*etiology MH - Human MH - Male MH - Middle Age MH - New Caledonia MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 881222 DP - 1988 Oct IS - 0003-3928 TA - Ann Cardiol Angeiol (Paris) PG - 449-53 SB - M CY - FRANCE IP - 8 VI - 37 JC - 502 AA - Author EM - 8902 AB - The authors report the cardiovascular manifestations observed in 15 cases of severe leptospirosis in New Caledonia. Cardiovascular collapse is frequent. Electrocardiographic alterations consist mainly of arrhythmia secondary to atrial fibrillation and repolarisation disorders. A picture of pseudo-pericarditis has also been observed. These cardiac manifestations represent a factor of gravity when associated with multi-visceral manifestations which control the prognosis. AD - Service de Cardiologie, HIA Sainte-Anne, Toulon-Naval. PMID- 3190146 TT - Manifestations cardiaques au cours des leptospiroses. A propos de 15 cas observes en Nouvelle-Caledonie. EA - A SO - Ann Cardiol Angeiol (Paris) 1988 Oct;37(8):449-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 89048056 AU - Edwards CN AU - Nicholson GD AU - Hassell TA AU - Everard CO AU - Callender J TI - Penicillin therapy in icteric leptospirosis. LA - Eng MH - Adult MH - Female MH - Human MH - Iritis/prevention & control MH - Male MH - Middle Age MH - Penicillins/*therapeutic use MH - Prospective Studies MH - Random Allocation MH - Weil's Disease/complications/*drug therapy RN - 0 (Penicillins) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - RANDOMIZED CONTROLLED TRIAL DA - 881125 DP - 1988 Oct IS - 0002-9637 TA - Am J Trop Med Hyg PG - 388-90 SB - A SB - M CY - UNITED STATES IP - 4 VI - 39 JC - 3ZQ AA - Author EM - 8902 AB - A prospective, controlled randomized study of penicillin therapy in icteric human leptospirosis was carried out between 1 October 1983 and 31 December 1986. Thirty-eight patients received intravenous crystalline penicillin for 5 days, while 41 assigned to a control group received intravenous fluids only. A comparison of the results of laboratory tests made on the day of admission revealed no significant differences between the 2 groups. There was no significant difference in time for defervescence, return of biochemical parameters to normal, incidence of iritis, or mortality in the 2 groups. Three patients (7.3%) in the control group and 1 patient (2.6%) in the treatment group died. The overall mortality rate was 5.9%. Leptospira were recovered from urine cultures in 6 control patients but from none of the treated patients' post-treatment cultures. We conclude that penicillin has little effect on clinical outcome in icteric leptospirosis. AD - Department of Medicine, Queen Elizabeth Hospital, Faculty of Medical Sciences, University of the West Indies. PMID- 3189700 CU - 94 SO - Am J Trop Med Hyg 1988 Oct;39(4):388-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 89151407 AU - Yang WY TI - [The geographic distribution of leptospirosis in Yunnan Province] LA - Chi MH - Altitude MH - China MH - Cohort Studies MH - *Disease Reservoirs MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Multicenter Studies MH - Weather PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - MULTICENTER STUDY DA - 890418 DP - 1988 Oct IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 257-60 CY - CHINA IP - 5 VI - 9 JC - CQG EM - 8906 PMID- 3067858 CU - 90 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1988 Oct;9(5):257-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 89016882 AU - Cunha BA TI - Systemic infections affecting the liver. Some cause jaundice, some do not. LA - Eng MH - Bacterial Infections/*complications/diagnosis MH - Human MH - Jaundice/*etiology/parasitology MH - Liver Abscess/complications MH - Pneumonia/complications MH - Protozoan Infections/complications MH - Virus Diseases/*complications/diagnosis PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 881115 DP - 1988 Oct IS - 0032-5481 TA - Postgrad Med PG - 148-58, 161-3, 166-8 SB - A SB - M CY - UNITED STATES IP - 5 VI - 84 JC - PFK AA - Author EM - 8901 AB - The patient who has clinical jaundice, abnormal results on liver function tests, or both presents a difficult diagnostic challenge. Many infectious diseases affect the liver, and the extent of involvement determines the degree of clinically apparent jaundice. Some diseases that affect the liver minimally cause no jaundice at all. An important clue to the cause of the disorder is the pattern of abnormal results on liver function tests. Increased alkaline phosphatase predominates with Q fever, secondary or tertiary syphilis, clonorchiasis, and hepatic candidiasis, while elevated levels of serum transaminases characterize viral hepatitis, leptospirosis, mononucleosis syndromes, legionnaires' disease, typhoid fever, toxic shock syndrome, and yellow fever. Increases in serum bilirubin are typical with jaundice caused by clostridial myelonecrosis, severe bacterial sepsis, and relapsing fever (borreliosis). These findings together with the patient's history, physical findings, and basic laboratory tests provide a presumptive diagnosis in most cases. AD - Infectious Disease Division, Winthrop-University Hospital, Mineola, NY 11501. RF - 17 PMID- 3050927 CU - 90 SO - Postgrad Med 1988 Oct;84(5):148-58, 161-3, 166-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [3 protein links] [1 nucleotide link] [203 medline neighbors] UI - 89008067 AU - Zuerner RL AU - Charon NW TI - Nucleotide sequence analysis of a gene cloned from Leptospira biflexa serovar patoc which complements an argE defect in Escherichia coli. LA - Eng MH - Amino Acid Sequence MH - Arginine/*biosynthesis MH - Base Sequence MH - Cloning, Molecular MH - Comparative Study MH - DNA Insertion Elements MH - DNA Mutational Analysis MH - DNA, Bacterial/genetics MH - *Genes, Bacterial MH - Genetic Complementation Test MH - Leptospira/*genetics MH - Restriction Mapping MH - RNA Polymerases/genetics MH - Support, U.S. Gov't, P.H.S. RN - EC 2.7.7.6 (RNA Polymerases) RN - 0 (DNA Insertion Elements) RN - 0 (DNA, Bacterial) RN - 7004-12-8 (Arginine) PT - JOURNAL ARTICLE ID - DE04645/DE/NIDR ID - S07-RR05433/RR/NCRR DA - 881114 DP - 1988 Oct IS - 0021-9193 TA - J Bacteriol PG - 4548-54 SB - M CY - UNITED STATES IP - 10 VI - 170 JC - HH3 AA - Author EM - 8901 AB - The genus Leptospira, as a member of the order Spirochaetales, forms one of the most ancient evolutionary branches of the eubacteria. These spirochetes are morphologically and physiologically different from most eubacteria, and little is known about Leptospira genetics. In this communication, we report the first nucleotide sequence of a Leptospira gene. A gene which complements an argE mutation in Escherichia coli was isolated from a plasmid-based genomic library composed of Leptospira biflexa serovar patoc DNA. The functional region for the complementing activity was localized by transposon mutagenesis and restriction enzyme mapping and by subcloning. Nucleotide sequence analysis indicated a single open reading frame within the region containing argE complementing activity. The size of the predicted protein, 31,071 daltons, was in excellent agreement with data obtained from coupled transcription-translation reactions primed with cloned L. biflexa DNA. One surprising result was that the predicted amino acid sequence of this protein closely resembles portions of the beta' subunits of RNA polymerases from bacteria and chloroplasts. AD - Department of Microbiology and Immunology, School of Medicine, West Virginia University, Morgantown 26506. PMID- 2844724 CU - 96 SI - GENBANK/M22622 SO - J Bacteriol 1988 Oct;170(10):4548-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 89307224 AU - Zhong WM AU - Dai BM AU - Wang YP AU - Yang ZM TI - [Studies on immunobiological properties of outer envelope of leptospires] LA - Chi MH - Animal MH - Bacterial Outer Membrane Proteins/immunology/*isolation & purification MH - Blotting, Western MH - Electrophoresis, Polyacrylamide Gel MH - English Abstract MH - Hamsters MH - Leptospira/*analysis/ultrastructure MH - Support, Non-U.S. Gov't RN - 0 (Bacterial Outer Membrane Proteins) PT - JOURNAL ARTICLE DA - 890818 DP - 1988 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 226-30 CY - CHINA IP - 3 VI - 19 JC - GEB EM - 8910 PMID- 3253165 CU - 91 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1988 Sep;19(3):226-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 89268613 AU - Nie DK AU - Shi MH AU - Zhu GF AU - Liu YM AU - Wu SH AU - Jiang SX AU - Wang HQ TI - [Studies on endotoxin of Leptospira. II. The effects of leptospiral lipopolysaccharides on rabbit's leukocytes and lethality to C57BL/6 mice] LA - Chi MH - Animal MH - English Abstract MH - *Leptospira MH - Lethal Dose 50 MH - Leukocytosis/*chemically induced MH - Lipopolysaccharides/*toxicity MH - Mice MH - Mice, Inbred C57BL MH - Rabbits RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 890710 DP - 1988 Sep IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 270-4 CY - CHINA IP - 3 VI - 28 JC - XNA EM - 8909 PMID- 3250098 CU - 91 EA - A SO - Wei Sheng Wu Hsueh Pao 1988 Sep;28(3):270-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 89115064 AU - Borcic B AU - Kovacic H AU - Sebek Z AU - Aleraj B AU - Tvrtkovic N TI - [A 10-year study of a single natural focus of leptospirosis in Posavina] LA - Scr MH - Animal MH - *Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/*epidemiology MH - Rodentia/*microbiology MH - Yugoslavia PT - JOURNAL ARTICLE DA - 890303 DP - 1988 Sep-Oct IS - 0042-8450 TA - Vojnosanit Pregl PG - 353-8 CY - YUGOSLAVIA IP - 5 VI - 45 JC - XHM EM - 8905 PMID- 3218108 TT - Deset godina ispitivanja jednog prirodnog zarista leptospiroza u Posavini. EA - A SO - Vojnosanit Pregl 1988 Sep-Oct;45(5):353-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 89057325 AU - Hunter P AU - Flamand JR AU - Myburgh J AU - van der Merwe SM TI - Serological reactions to Leptospira species in game animals of northern Natal. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals, Wild/*immunology MH - Disease Reservoirs MH - Leptospirosis/immunology/*veterinary MH - Serodiagnosis MH - South Africa PT - JOURNAL ARTICLE DA - 890103 DP - 1988 Sep IS - 0030-2465 TA - Onderstepoort J Vet Res PG - 191-2 SB - M CY - SOUTH AFRICA IP - 3 VI - 55 JC - OI6 AA - Author EM - 8903 AB - Fifty sera collected from 12 different species of free-living game animals in game parks in the Northern Natal were tested against 8 Leptospira interrogans antigens using the microscopic agglutination test (MAT). Six out of 50 animals had titres, all less than 100. Three of these animals had titres to serovar mini, 1 animal to tarrasovi, and 3 animals had multi-serovar reactions, 1 to mini and hardjo, and 1 to tarrasovi, copenhageni and pomona. AD - Veterinary Research Institute, Onderstepoort. PMID- 3194123 SO - Onderstepoort J Vet Res 1988 Sep;55(3):191-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 89049952 AU - Palit A AU - Cox J AU - Hollingworth J AU - Sheers J TI - Prevention of Leptospira interrogans serovar pomona infection in domestic pigs by vaccination. LA - Eng MH - Animal MH - Animals, Domestic MH - Comparative Study MH - Evaluation Studies MH - Immunization, Secondary/veterinary MH - Leptospira interrogans MH - Swine MH - Swine Diseases/*prevention & control MH - Time Factors MH - Vaccination/*veterinary MH - Weil's Disease/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 881201 DP - 1988 Sep IS - 0005-0423 TA - Aust Vet J PG - 289-90 SB - M CY - AUSTRALIA IP - 9 VI - 65 JC - 9IE EM - 8902 AD - Commonwealth Serum Laboratories, Parkville, Victoria. PMID- 3190600 CU - 90 SO - Aust Vet J 1988 Sep;65(9):289-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 89085926 AU - Chekhovich AV AU - Chernukha IuG AU - Evdokimova OA AU - Reichuk EA AU - Anan'ina IuV TI - [The functioning of a drained natural focus of leptospirosis in a nonchernozem area] LA - Rus MH - Agriculture MH - Animal MH - Animal Husbandry MH - Animals, Wild MH - Antibodies, Bacterial/analysis MH - Comparative Study MH - *Disease Reservoirs MH - Disease Vectors MH - Ecology MH - English Abstract MH - Fresh Water MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology/immunology/transmission/veterinary MH - Russia RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890209 DP - 1988 Sep IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 51-6 SB - M CY - USSR IP - 9 JC - Y9O AA - Author EM - 8904 AB - The drainage of a natural focus of leptospirosis of the flood plain- swamp type, carried out over the period of 15 years, has led to changes in the species structure of small mammals and to an increase in the number of Leptospira-carrying species. Nevertheless, like before drainage, the prevalent species and the main carrier of leptospires is still the root vole (Microtus oeconomus Pallas). The intensity of the epizootic process among small mammals at the final stage of drainage has proved to be similar to that at the initial stage. At the same time the cultivated fields created on the drained territory of the natural focus abound, by the time of harvesting, with small mammals among whom the intensive epizootic process takes place. PMID- 2974674 CU - 92 TT - Funktsionirovanie osushennogo prirodnogo ochaga leptospirozov v Nechernozem'e. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1988 Sep;(9):51-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 89307225 AU - Bao L AU - Dai BM TI - [Analysis of restriction endonuclease pattern and observation by EM with spreading-monolayer of DNA on alkaline-protein film (EMSMDAPF) in DNA of leptospires] LA - Chi MH - Animal MH - DNA Restriction Enzymes MH - DNA, Bacterial/*analysis/ultrastructure MH - Electrophoresis, Agar Gel MH - English Abstract MH - Leptospira/classification/*genetics MH - Restriction Mapping MH - Support, Non-U.S. Gov't RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 890818 DP - 1988 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 231-4 CY - CHINA IP - 3 VI - 19 JC - GEB EM - 8910 PMID- 2855322 CU - 93 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1988 Sep;19(3):231-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 89011865 AU - Jost BH AU - Adler B AU - Faine S TI - Reaction of monoclonal antibodies with species specific determinants in Leptospira interrogans outer envelope. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Monoclonal/*immunology MH - Antigens, Bacterial/*immunology MH - Antigens, Surface/immunology MH - Blotting, Western MH - Cell Membrane/ultrastructure MH - Chromatography, Affinity MH - Electrophoresis, Polyacrylamide Gel MH - Epitopes/immunology MH - IgG/immunology MH - Immunodiffusion MH - Immunoenzyme Techniques MH - Immunohistochemistry MH - Leptospira interrogans/*immunology/ultrastructure MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Antigens, Surface) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 881108 DP - 1988 Sep IS - 0022-2615 TA - J Med Microbiol PG - 51-7 SB - M CY - ENGLAND IP - 1 VI - 27 JC - J2N AA - Author EM - 8901 AB - A set of 24 monoclonal antibodies (MABs) was produced against an outer envelope preparation from Leptospira interrogans serovar copenhageni. The MABs reacted in enzyme immunoassay with species-specific determinants of an antigen in the leptospiral outer envelope (OE) of pathogenic but not of saprophytic species of Leptospira. The MABs did not agglutinate whole leptospires, nor could they opsonise homologous leptospires for phagocytosis by mouse macrophages or protect new-born guinea-pigs against lethal infection. The MABs reacted by Western blotting with a 35 x 10(3)-mol-wt band in OE separated on SDS- polyacrylamide gels, and also reacted with other bands to a lesser extent. The determinants to which the MABs were directed were localised in the leptospiral OE by immunogold labelling techniques. AD - Department of Microbiology, Monash University, Clayton, Victoria, Australia. PMID- 2459387 CU - 95 SO - J Med Microbiol 1988 Sep;27(1):51-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 88301680 AU - Davies EA AU - Rooney PJ AU - Coyle PV AU - Simpson DI AU - Montgomery IW AU - Stanford CF TI - Hantavirus and Leptospira [letter] LA - Eng MH - Hantavirus MH - Hemorrhagic Fevers, Viral/*complications MH - Human MH - Leptospirosis/*complications MH - Northern Ireland PT - LETTER DA - 880921 DP - 1988 Aug 20 IS - 0140-6736 TA - Lancet PG - 460-1 SB - A SB - M SB - X CY - ENGLAND IP - 8608 VI - 2 JC - L0S EM - 8811 PMID- 2900396 CU - 94 SO - Lancet 1988 Aug 20;2(8608):460-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 89346476 AU - Zamora J AU - Riedemann S AU - Leal H AU - Jackson C TI - [Serologic evidence of leptospirosis in rice field workers] LA - Spa MH - Adult MH - Agglutination Tests/methods MH - *Agriculture MH - Antibodies, Bacterial/analysis MH - Chile MH - English Abstract MH - Human MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis MH - Male MH - Middle Age MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890918 DP - 1988 Aug IS - 0034-9887 TA - Rev Med Chil PG - 723-8 CY - CHILE IP - 8 VI - 116 JC - SHD EM - 8911 PMID- 3255123 CU - 91 TT - Evidencia serologica de leptospirosis en labradores de arrozales. EA - A SO - Rev Med Chil 1988 Aug;116(8):723-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 89316725 AU - de Souza D TI - [Human leptospirosis--an infection in the residents of the Aricanduva River valley, the city of Sao Paulo, 1984-5. II. The serological aspects] LA - Por MH - Antibodies, Bacterial/analysis MH - Brazil MH - English Abstract MH - Fresh Water MH - Human MH - IgM/analysis MH - Leptospira/immunology MH - Leptospirosis/diagnosis/*epidemiology MH - Serodiagnosis MH - *Urban Population RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890825 DP - 1988 Aug IS - 0080-6234 TA - Rev Esc Enferm USP PG - 159-68 SB - N CY - BRAZIL IP - 2 VI - 22 JC - RSS EM - 8910 PMID- 3253865 CU - 91 LI - N TT - Leptospirose humana--infeccao em habitantes do vale do rio Aricanduva, municipio de Sao Paulo, 1984-5. Parte II--aspectos sorologicos. EA - A SO - Rev Esc Enferm USP 1988 Aug;22(2):159-68 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 89085687 AU - Lutsik BD AU - Titov MB AU - Sobko IuF AU - Bel'dii VI TI - [Characteristics of leptospiral meningitis] LA - Rus MH - Antibodies, Bacterial/analysis MH - Human MH - Leptospira interrogans/immunology MH - Meningitis/*diagnosis/etiology MH - Weil's Disease/complications/*diagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890202 DP - 1988 Aug IS - 0049-6804 TA - Vrach Delo PG - 110-2 CY - USSR IP - 8 JC - XLS EM - 8904 PMID- 3206869 CU - 91 TT - Osobennosti leptospiroznogo meningita. SO - Vrach Delo 1988 Aug;(8):110-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 89059663 AU - Chernukha IuG AU - Boroznov NI AU - Anan'ina IuV TI - [Populations of pathogenic Leptospira of varying virulence in nature] LA - Rus MH - Animal MH - Disease Reservoirs MH - English Abstract MH - Hamsters MH - Kidney/microbiology MH - Leptospira interrogans/isolation & purification/*pathogenicity MH - Rats/microbiology MH - Serial Passage MH - USSR MH - Virulence MH - Weil's Disease/microbiology PT - JOURNAL ARTICLE DA - 881228 DP - 1988 Aug IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 13-6 SB - M CY - USSR IP - 8 JC - Y9O AA - Author EM - 8903 AB - The study of geographically remote populations of Norway rats (Rattus norvegicus) revealed that in one of these populations a highly virulent population of Leptospira copenhageni, serogroup icterohaemorrhagiae, and in another population of rats a faintly virulent population of these microorganisms circulated simultaneously. At the same time in vitro experiments with Leptospira cultures showed the absence of the constant probability of sharp changes in the level of their virulence in time. PMID- 3195265 CU - 90 TT - Populiatsii patogennykh leptospir razlichnoi virulentnosti v prirode. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1988 Aug;(8):13-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 89043427 AU - Bonard EC TI - [Leptospirosis] LA - Fre MH - Adult MH - Agricultural Workers' Diseases/diagnosis MH - Case Report MH - Disease Reservoirs MH - Human MH - Leptospirosis/diagnosis/drug therapy/transmission MH - Male MH - Middle Age MH - Penicillins/therapeutic use MH - Weil's Disease/diagnosis/drug therapy/*transmission RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 881212 DP - 1988 Aug IS - 0035-3655 TA - Rev Med Suisse Romande PG - 683-90 CY - SWITZERLAND IP - 8 VI - 108 JC - SR5 EM - 8902 PMID- 3187284 CU - 92 TT - Leptospiroses. SO - Rev Med Suisse Romande 1988 Aug;108(8):683-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 89280284 AU - Kanai K AU - Dejsirilert S TI - Pseudomonas pseudomallei and melioidosis, with special reference to the status in Thailand. LA - Eng MH - Human MH - Melioidosis/epidemiology/*physiopathology MH - Pseudomonas/*classification/isolation & purification MH - Support, Non-U.S. Gov't MH - Thailand PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, ACADEMIC DA - 890721 DP - 1988 Aug IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 123-57 SB - M CY - JAPAN IP - 4 VI - 41 JC - KLZ AA - Author EM - 8909 AB - Melioidosis is a long-known disease since 1912, but only quite recently we have obtained the knowledges about its actual clinical and epidemiological features. The disease is so unique in having a wide spectrum of disease course and clinical manifestation. The causative agent, P. pseudomallei, is free-living bacterium in the natural environments (soil and surface water) of tropical and subtropical areas. Just like legionnaires' disease, melioidosis is a good example of infectious disease in which pneumonia is produced by inhalation of contaminated soil dusts or water droplets. The infection becomes dormant for years, but with a chance of recrudescence under a variety of insults to the host resistance. The disease, may it be acute or chronic, will be symptomatically confused with malaria, typhoid fever, leptospirosis, septicemia caused by other gram-negative bacteria, tuberculosis and mycotic infections. Isolation of the causative agent from clinical specimens is the only reliable method for diagnosis. Because of the increasing clinical awareness and the development of diagnostic methods, the reported cases of melioidosis have numbered almost one thousand in Thailand during the past 20 years. This country has now the most ample clinical experiences on melioidosis. We have reviewed the history of melioidosis research from bacteriological, immunological, clinical and epidemiological viewpoints, especially including the recent reports in Thailand. AD - National Institute of Health, Soi Bamrasnaradura Hospital, Amphur Muang, Nonthaburi, Thailand. RF - 158 PMID- 3075004 CU - 90 SO - Jpn J Med Sci Biol 1988 Aug;41(4):123-57 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 88307752 AU - Lee M AU - Lambros C TI - Use of avidin-biotin-glucose oxidase complex to detect antimalarial antibody in serum by light microscopy. LA - Eng MH - Animal MH - Antibodies, Protozoan/*analysis MH - Avidin MH - Biotin MH - Comparative Study MH - Cross Reactions MH - Fluorescent Antibody Technique MH - Glucose Oxidase MH - Human MH - *Immunoenzyme Techniques MH - Malaysia MH - Melanesia MH - Microscopy MH - Plasmodium falciparum/*immunology RN - EC 1.1.3.4 (Glucose Oxidase) RN - 0 (Antibodies, Protozoan) RN - 1405-69-2 (Avidin) RN - 58-85-5 (Biotin) PT - JOURNAL ARTICLE DA - 880919 DP - 1988 Aug IS - 0002-9637 TA - Am J Trop Med Hyg PG - 145-9 SB - A SB - M CY - UNITED STATES IP - 2 VI - 39 JC - 3ZQ AA - Author EM - 8811 AB - An immunohistochemical assay was developed combining an avidin-biotin- glucose oxidase complex procedure (ABC-GO) with light microscopy to detect specific antibody against Plasmodium falciparum. Thin blood films were prepared from culture material of P. falciparum and fixed with acetone. Antibody was detected by successive incubations with test serum, biotinylated goat antihuman antibody, avidin-biotin-glucose oxidase complex, and glucose oxidase substrate. In the presence of reactive serum, a blue precipitate formed on the parasites and could be visually observed with a 40x objective. Sera from patients with single infections for P. vivax or P. ovale were unreactive. No cross- reactivity was observed with sera from patients with rheumatoid arthritis, filariasis, amebiasis, schistosomiasis, dengue, scrub typhus, leptospirosis, or toxoplasmosis. The sensitivity of ABC-GO is comparable to that of the indirect fluorescent antibody test. AD - U.S. Army Medical Research Unit, Institute for Medical Research, Kuala Lumpur, Malaysia. PMID- 3044152 CU - 91 SO - Am J Trop Med Hyg 1988 Aug;39(2):145-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 88275677 AU - Wilkins E AU - Cope A AU - Waitkins S TI - Rapids, rafts, and rats [letter] LA - Eng MH - Animal MH - *Fresh Water MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - Rats MH - *Sports MH - Thailand MH - Travel MH - *Water RN - 7732-18-5 (Water) PT - LETTER DA - 880825 DP - 1988 Jul 30 IS - 0140-6736 TA - Lancet PG - 283-4 SB - A SB - M SB - X CY - ENGLAND IP - 8605 VI - 2 JC - L0S EM - 8810 PMID- 2899276 CU - 94 SO - Lancet 1988 Jul 30;2(8605):283-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 88290147 AU - Ercolani MG AU - Papa M TI - [Clinico-radiological observations on pulmonary manifestations of leptospirosis during the Montefeltro epidemic] LA - Ita MH - Adult MH - Case Report MH - Disease Outbreaks/*epidemiology MH - English Abstract MH - Female MH - Human MH - Italy MH - Leptospirosis/diagnosis/epidemiology/*radiography MH - Lung Diseases/diagnosis/epidemiology/*radiography MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 880908 DP - 1988 Jul-Aug IS - 0033-8362 TA - Radiol Med (Torino) PG - 64-7 SB - M SB - X CY - ITALY IP - 1-2 VI - 76 JC - RBZ AA - Author EM - 8811 AB - During the summer of 1984, in the Montefeltro area an epidemic of leptospirosis took place from a common source. In 15% of the people affected, the disease involved the lungs. In 3 patients the disease had a deadly course; one decrease was due to ARDS. The clinical, anatomopathological, and radiological features are described of the patients who presented with lung involvement. Such an outcome proved to be more likely than we thought. X-ray pattern of the chest was a polymorphous appearance, in spite of the same anatomopathological substratum, characterized by lung edema and endoalveolar hemorrhages. AD - Reparto di Radiologia, Ospedale Civile, Novafeltria. PMID- 3399710 CU - 88 TT - Osservazioni clinico-radiologiche sulle manifestazioni polmonari da leptospirosi durante l'epidemia del Montefeltro. EA - A SO - Radiol Med (Torino) 1988 Jul-Aug;76(1-2):64-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 88274105 AU - Bolin CA AU - Koellner P TI - Human-to-human transmission of Leptospira interrogans by milk [letter] LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/transmission MH - Female MH - Human MH - Infant MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*transmission MH - *Milk, Human MH - Occupational Diseases/etiology MH - Pregnancy MH - Pregnancy Complications, Infectious/veterinary PT - LETTER DA - 880817 DP - 1988 Jul IS - 0022-1899 TA - J Infect Dis PG - 246-7 SB - A SB - M CY - UNITED STATES IP - 1 VI - 158 JC - IH3 EM - 8810 PMID- 3392418 CU - 91 SO - J Infect Dis 1988 Jul;158(1):246-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 89032648 AU - Cinco M AU - Banfi E AU - Giani M AU - Gundelach ML AU - Galanos C TI - Chemical and biological properties of a phenol-water extract from Leptospira interrogans. Evidence for the absence of lipopolysaccharide. LA - Eng MH - Animal MH - Carbohydrates/analysis MH - Electrophoresis, Polyacrylamide Gel MH - Fatty Acids/analysis MH - Human MH - Leptospira interrogans/*analysis MH - Lipopolysaccharides/*analysis/immunology/toxicity MH - Macrophage Activation MH - Mice MH - Mice, Inbred C57BL MH - Phenols MH - Shwartzman Phenomenon MH - Water RN - 0 (Fatty Acids) RN - 0 (Lipopolysaccharides) RN - 0 (Phenols) RN - 108-95-2 (phenol) RN - 7732-18-5 (Water) PT - JOURNAL ARTICLE DA - 881212 DP - 1988 Jul-Aug IS - 0300-8126 TA - Infection PG - 238-41 SB - M CY - GERMANY, WEST IP - 4 VI - 16 JC - GO8 AA - Author EM - 8902 AB - Leptospira interrogans, serovar copenhageni was extracted by the phenol- water method and the resulting preparation examined for chemical composition and endotoxic activity. Chemical analysis revealed that a number of sugars were present, however, the amount of lipid content was very low. Further, the preparation was devoid of characteristic endotoxic properties, like lethal toxicity, pyrogenicity and the property to induce the local Shwartzman reaction. The extract, however, was active in the limulus lysate gelation test and in the induction of monocyte activation. It is concluded that the leptospira preparation is devoid of endotoxin properties, both from the chemical and from the biological point of view. AD - Instituto di Microbiologia, Universita degli Studi di Trieste. PMID- 3182088 CU - 92 SO - Infection 1988 Jul-Aug;16(4):238-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 89021522 AU - Ito T AU - Takimoto T AU - Yanagawa R TI - Presence of a variety of antigenic variants belonging to at least 4 different serovars in a population of Leptospira interrogans serovar hebdomadis. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/immunology MH - Antibodies, Monoclonal/immunology MH - Antigenic Variation MH - Antigens, Bacterial/*analysis MH - Cross Reactions MH - Leptospira interrogans/classification/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 881123 DP - 1988 Jul IS - 0176-6724 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 15-25 SB - M CY - GERMANY, WEST IP - 1 VI - 269 JC - Y55 AA - Author EM - 8901 AB - The presence of antigenic variants belonging to at least 4 different serovars, jules, kremastos and 2 new serovars, was demonstrated in a population of cloned Leptospira interrogans serovar hebdomadis. Thirteen antigenic variants were isolated from the clone of serovar hebdomadis by culturing in the presence of 13 monoclonal antibodies against 5 serovars, hebdomadis, worsfoldi, kambale, jules and kremastos Kyoto, respectively. These variants were divided into 4 groups, based on the reactivity with the above monoclonal antibodies. Four antigenic variants, one each from the 4 groups, were identified as jules, kremastos and 2 different new serovars. The variation frequency of the 13 antigenic variants ranged from 10(-5.48) to 10(-7.70) except for one, whose frequency was as high as 10(-1.31). AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. PMID- 3176752 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1988 Jul;269(1):15-25 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 89021530 AU - Cacciapuoti B AU - Ciceroni L AU - Saito T AU - Ono E AU - Yanagawa R TI - Broad reacting surface antigens in Leptospira biflexa serovar andamana. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/immunology MH - Antigens, Bacterial/*immunology MH - Antigens, Surface/immunology MH - Comparative Study MH - Complement Fixation Tests MH - Cross Reactions MH - Epitopes/analysis MH - Human MH - Leptospira/*immunology/ultrastructure MH - Leptospirosis/*immunology MH - Microscopy, Electron MH - Rabbits MH - Species Specificity RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Antigens, Surface) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 881123 DP - 1988 Jul IS - 0176-6724 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 86-99 SB - M CY - GERMANY, WEST IP - 1 VI - 269 JC - Y55 AA - Author EM - 8901 AB - Previous investigations had demonstrated that genus-specific and species-specific antigens of leptospires are deep-seated within the leptospiral cell. Conversely, the present study has shown that strain CH11, serovar andamana of the non-pathogenic species of Leptospira biflexa is endowed on its surface with two cross-reacting antigens; a newly recognized antigen common to L. interrogans and L. biflexa spp. and an antigenic determinant common to a previously described genus- specific protein antigen (GP-Ag). The serovar andamana, when thimerosal- treated, behaved like an interspecies-specific antigen, cross-reacting in the complement fixation test with sera from rabbits immunized with L. interrogans and L. biflexa spp. and with sera from subjects with leptospirosis from various serovars. In the immuno electron microscopic test, human leptospirotic sera bound to the surface of thimerosal- treated andamana and not to the surface of untreated andamana showing that an interspecies-specific antigen was located underneath the outermost layer of this serovar. In the same test, the monoclonal antibody GP-7 against the GP-Ag bound to the surface of untreated andamana and not to the surface of thimerosal-treated andamana, showing that an antigenic determinant, common to GP-Ag and different from the first one, was located on the outer membrane of andamana. In human leptospirotic sera, antibodies against the cross-reacting antigen of thimerosal-treated andamana demonstrated by the complement fixation test were formed earlier and in a higher percentage of sera than the serovar-specific antibodies against 16 L. interrogans serovars demonstrated by the microagglutination test. AD - National Center for Leptospirosis, Istituto Superiore di Sanita, Roma, Italy. PMID- 2459865 CU - 95 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1988 Jul;269(1):86-99 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 88276465 AU - Ribiczey P AU - Szekeres I AU - Turoczi I TI - [Acute pancreatitis as a complication of leptospirosis] LA - Hun MH - Adult MH - Animal MH - Case Report MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Mice MH - Middle Age MH - Pancreatitis/diagnosis/*etiology MH - Rats MH - Ultrasonography MH - Zoonoses PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 880818 DP - 1988 Jun 26 IS - 0030-6002 TA - Orv Hetil PG - 1367-9 CY - HUNGARY IP - 26 VI - 129 JC - OL8 EM - 8810 RF - 24 PMID- 3292991 CU - 90 TT - Az akut pancreatitis, mint a leptospirosis szovodmenye. EA - A SO - Orv Hetil 1988 Jun 26;129(26):1367-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 88289689 AU - Law-Koune JD AU - Picard P AU - Van Der Linden T AU - Michault A AU - Corbin JC AU - Duval G TI - [Thrombocytopenia in leptospirosis. Role of anti-platelet antibodies (letter)] LA - Fre MH - Adult MH - Antibodies/*analysis MH - Blood Platelets/*immunology MH - Case Report MH - Human MH - Middle Age MH - Thrombocytopenia/*immunology MH - Weil's Disease/*complications RN - 0 (Antibodies) PT - LETTER DA - 880906 DP - 1988 Jun 25 IS - 0755-4982 TA - Presse Med PG - 1315-6 SB - M SB - X CY - FRANCE IP - 25 VI - 17 JC - PMT EM - 8811 PMID- 2969585 CU - 92 TT - Thrombopenie au cours de la leptospirose. Role des anticorps anti- plaquettes. SO - Presse Med 1988 Jun 25;17(25):1315-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 88245996 AU - Kudesia G AU - Christie P AU - Walker E AU - Pinkerton I AU - Lloyd G TI - Dual infection with leptospira and hantavirus [letter] LA - Eng MH - Adolescence MH - Case Report MH - Hantavirus MH - Hemorrhagic Fever with Renal Syndrome/*complications MH - Human MH - Male MH - Weil's Disease/*complications PT - LETTER DA - 880721 DP - 1988 Jun 18 IS - 0140-6736 TA - Lancet PG - 1397 SB - A SB - M SB - X CY - ENGLAND IP - 8599 VI - 1 JC - L0S EM - 8809 PMID- 2898071 CU - 94 SO - Lancet 1988 Jun 18;1(8599):1397 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 89146361 AU - Heisey GB AU - Nimmanitya S AU - Karnchanachetanee C AU - Tingpalapong M AU - Samransamruajkit S AU - Hansukjariya P AU - Elwell MR AU - Ward GS TI - Epidemiology and characterization of leptospirosis at an urban and provincial site in Thailand. LA - Eng MH - Animal MH - Cattle MH - Dogs MH - Fever of Unknown Origin/etiology MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/complications/diagnosis/*epidemiology MH - Rural Population MH - Thailand MH - Urban Population PT - JOURNAL ARTICLE DA - 890329 DP - 1988 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 317-22 SB - M CY - THAILAND IP - 2 VI - 19 JC - UVN AA - Author EM - 8906 AB - Patients with FUOs at the Children's Hospital in Bangkok and the Chao Phya Abhai Bhu Bejhr Hospital in Prachinburi were screened for leptospirosis by blood and urine culture in addition to microagglutination testing of their serum. Animal populations in urban and periurban areas of Bangkok were surveyed for evidence of leptospira infection. Three rural sites near the Prachinburi Provincial Hospital were also surveyed. The rodents' and domestic animals' blood, urine, and/or kidney cell samples were cultured for leptospira. Sera from these animals were also tested for leptospira antibody. The bataviae serovar was the most commonly detected leptospiral agent in both man and animals. Presenting symptoms varied with age with children showing primarily fever, vomiting, headache, abdominal and generalized muscle pain and diarrhea whereas adults had fever, headache, anorexia, muscle pain and constipation. Blood samples from patients suspected of having leptospirosis were tested for antibody by the MAT and cultured in EMJH media. The following serogroups were identified: bataviae, autumanalis, javanica, hebdomadis, and pyrogens. Leptospirosis incidence in humans was much higher in the rainy/flooding year of 1983 compared to the relatively dry year of 1984. Results of our animal surveillance studies indicate that in addition to rats, which have previously been mentioned, dogs, bandicoots, cattle and pigs could be the source of human leptospirosis infection in both urban and provincial locations in Thailand. AD - Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand. PMID- 3227409 SO - Southeast Asian J Trop Med Public Health 1988 Jun;19(2):317-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 89146345 AU - Padre LP AU - Watt G AU - Tuazon ML AU - Gray MR AU - Laughlin LW TI - A serologic survey of rice-field leptospirosis in Central Luzon, Philippines. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agricultural Workers' Diseases/epidemiology MH - Antibodies, Bacterial/*analysis MH - Female MH - Human MH - Leptospira interrogans/*immunology MH - Male MH - Middle Age MH - Philippines MH - Rice MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Weil's Disease/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890329 DP - 1988 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 197-9 SB - M CY - THAILAND IP - 2 VI - 19 JC - UVN AA - Author EM - 8906 AB - Although human cases of leptospirosis have been reported from the Philippines, there is a lack of data on its prevalence. We therefore surveyed three rice-farming villages for the presence of leptospiral antibody. Out of 155 sera tested, 63 (43.6%) tested positive using the standard microagglutination test. Antibodies were more frequent in men than women (48 vs. 31%, respectively, p less than 0.01), and less common in the elderly. Exposure to leptospires occurs frequently in rice farmers, and leptospirosis is likely to be an underdiagnosed cause of both mild and severe febrile illness in the Philippines. AD - U.S. Naval Medical Research Unit No. 2, Manila, Philippines. PMID- 3227399 CU - 91 SO - Southeast Asian J Trop Med Public Health 1988 Jun;19(2):197-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 89073816 AU - Li CZ AU - Li ZH AU - Gao JY TI - [Identification of four new strains Leptospira] LA - Chi MH - Animal MH - English Abstract MH - Human MH - Kidney/microbiology MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/microbiology MH - Muridae/microbiology MH - Nomenclature MH - Serotyping MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 890126 DP - 1988 Jun IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 173-8 CY - CHINA IP - 2 VI - 28 JC - XNA EM - 8903 PMID- 3201780 EA - A SO - Wei Sheng Wu Hsueh Pao 1988 Jun;28(2):173-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 89073815 AU - Zhang FZ AU - Zhou CY AU - Wang XY TI - [Two new serovars belonging to Leptospira hebdomadis serogroup] LA - Chi MH - English Abstract MH - Human MH - Leptospira interrogans/*classification/isolation & purification MH - Nomenclature MH - Serotyping MH - Weil's Disease/*microbiology PT - JOURNAL ARTICLE DA - 890126 DP - 1988 Jun IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 167-72 CY - CHINA IP - 2 VI - 28 JC - XNA EM - 8903 PMID- 3201779 EA - A SO - Wei Sheng Wu Hsueh Pao 1988 Jun;28(2):167-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 89065671 AU - Cheng SQ AU - Zhu G AU - Dai BM AU - Chai H TI - [Determination of deoxyribonucleic acid base composition of several leptospiral serovars] LA - Chi MH - Animal MH - Base Composition MH - DNA, Bacterial/*analysis MH - English Abstract MH - Human MH - Leptospira/*analysis/classification MH - Leptospira interrogans/analysis MH - Methods RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 890125 DP - 1988 Jun IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 132-4 CY - CHINA IP - 2 VI - 19 JC - GEB EM - 8903 PMID- 3198091 CU - 91 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1988 Jun;19(2):132-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 89146343 AU - Lane EM AU - Ramaley RF AU - Miller NG TI - Hemolysin production by Leptospira interrogans serovar canicola in a protein-free medium with hemin. LA - Eng MH - Culture Media MH - Cytochrome c/pharmacology MH - Heme/*analogs & derivatives MH - Hemin/*pharmacology MH - Hemolysins/*biosynthesis MH - Leptospira canicola/growth & development/metabolism MH - Leptospira interrogans/growth & development/*metabolism MH - Porphyrins/pharmacology MH - Proteins RN - 0 (Culture Media) RN - 0 (Hemolysins) RN - 0 (Porphyrins) RN - 14875-96-8 (Heme) RN - 16009-13-5 (Hemin) RN - 9007-43-6 (Cytochrome c) PT - JOURNAL ARTICLE DA - 890329 DP - 1988 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 187-90 SB - M CY - THAILAND IP - 2 VI - 19 JC - UVN AA - Author EM - 8906 AB - Leptospira interrogans serovar canicola strain moulton was grown to a high cell density in a protein-free medium. When hemin was added to this medium, hemolysin was produced. Hemolysin was not detected when other porphyrins or cytochrome C were substituted for hemin in the medium. AD - Department of Medical Microbiology, University of Nebraska College of Medicine, Omaha 68105. PMID- 2852404 CU - 93 SO - Southeast Asian J Trop Med Public Health 1988 Jun;19(2):187-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 88210983 AU - McCrindle BW AU - Wood RA AU - Nussbaum AR TI - Henoch-Schonlein syndrome. Unusual manifestations with hydrops of the gallbladder. LA - Eng MH - Case Report MH - Child, Preschool MH - Edema/epidemiology/*etiology MH - Gallbladder Diseases/epidemiology/*etiology MH - Human MH - Male MH - Purpura, Schoenlein-Henoch/*complications MH - Recurrence MH - Syndrome PT - JOURNAL ARTICLE DA - 880613 DP - 1988 May IS - 0009-9228 TA - Clin Pediatr (Phila) PG - 254-6 SB - A SB - M CY - UNITED STATES IP - 5 VI - 27 JC - DHE AA - Author EM - 8808 AB - Henoch-Schonlein Syndrome (HSS) is characterized by the presence of purpuric skin lesions, colicky abdominal pain, renal manifestations, and arthritis. We report a case complicated by several unusual manifestations, including hydrops of the gallbladder and extreme thrombocytosis. Gallbladder hydrops has been known to occur in association with several conditions including Kawasaki syndrome, scarlet fever, and leptospirosis, but no previous report of this occurring in a patient with HSS could be found. The hydrops in our patient resolved spontaneously without specific medical or surgical treatment. AD - Department of Pediatrics, Johns Hopkins Hospital, Baltimore, MD 21205. PMID- 3365907 CU - 90 SO - Clin Pediatr (Phila) 1988 May;27(5):254-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 88230424 AU - Kelson JS AU - Adler B AU - Chapman AJ AU - Faine S TI - Identification of leptospiral flagellar antigens by gel electrophoresis and immunoblotting. LA - Eng MH - Antigens, Bacterial/*analysis/immunology MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel MH - Flagella/*immunology/ultrastructure MH - Immunologic Techniques MH - Leptospira/*immunology MH - Microscopy, Electron MH - Molecular Weight MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 880630 DP - 1988 May IS - 0022-2615 TA - J Med Microbiol PG - 47-53 SB - M CY - ENGLAND IP - 1 VI - 26 JC - J2N AA - Author EM - 8809 AB - Flagella extracted from five serovars, representative of the pathogenic and saprophytic species of the Leptospiraceae, were morphologically similar. Analysis of Leptospira interrogans flagellar preparations by polyacrylamide gel electrophoresis revealed three common major bands in the (30-40) x 10(3)-mol. wt region, and serovar-specific bands in the lower region of the gels. Although some differences were observed, flagella extracted from L. biflexa serovar patoc and Leptonema illini revealed similar electrophoretic profiles to those seen in L. interrogans flagella. Immunoblot analysis showed that while flagellar components in the (20-30) x 10(3)-mol. wt region were recognised only by homologous rabbit antisera, a major protein doublet of (33-34) X 10(3)-mol. wt, depending on the species, was also demonstrated by heterologous antisera. The serovar-specific bands in the (20-30) x 10(3)-mol. wt region were composed of lipopolysaccharide (LPS). These results show that leptospiral flagella are immunogenic and contain antigens which are conserved among the different genera of the family Leptospiraceae. AD - Department of Microbiology, Monash University, Clayton, Melbourne, Australia. PMID- 3286874 CU - 91 SO - J Med Microbiol 1988 May;26(1):47-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 88323403 AU - Kondratenko VF AU - Bunin IK AU - Rodionova NS AU - Danilkin AP AU - Iagovkin EA TI - [A natural focus of icterohemorrhagic leptospirosis in the floodplain of the lower Don and means for its eradication] LA - Rus MH - Animal MH - Animals, Wild MH - Disease Reservoirs/*veterinary MH - English Abstract MH - Fresh Water MH - Human MH - Mice MH - Microtinae MH - Muridae MH - Rats MH - Rodent Control/methods MH - Rodent Diseases/epidemiology/prevention & control MH - Russia MH - Weil's Disease/epidemiology/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 881006 DP - 1988 May IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 38-41 SB - M CY - USSR IP - 5 JC - Y9O AA - Author EM - 8812 AB - An active natural focus of icterohemorrhagic leptospirosis has been detected in the area of fish-breeding ponds in Rostov Province, where the intensive epizootic among the population of Norway rats is observed the whole year round (574 animals have been examined, 56 cultures have been isolated). The epizootic process reaches its highest intensity in autumn (the proportion of infected animals exceeds 50%). This natural focus in the area of fish-breeding ponds is epidemiologically dangerous. The limitation of its infectious potential is possible by means of poisoned baits. PMID- 2970742 CU - 92 TT - Prirodnyi ochag ikterogemorragicheskogo leptospiroza v poime Nizhnego Dona i puti ego ozdorovleniia. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1988 May;(5):38-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 88304918 AU - Ellis WA AU - Thiermann AB AU - Montgomery J AU - Handsaker A AU - Winter PJ AU - Marshall RB TI - Restriction endonuclease analysis of Leptospira interrogans serovar hardjo isolates from cattle. LA - Eng MH - Animal MH - Cattle/*microbiology MH - *DNA Restriction Enzymes MH - DNA, Bacterial/*analysis MH - Electrophoresis MH - Genotype MH - Leptospira interrogans/*classification/genetics/isolation & purification MH - Serotyping RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 880921 DP - 1988 May IS - 0034-5288 TA - Res Vet Sci PG - 375-9 SB - M CY - ENGLAND IP - 3 VI - 44 JC - R7D AA - Author EM - 8811 AB - The genomes of 253 strains of Leptospira interrogans serovar hardjo were examined by restriction endonuclease analysis of their DNA. The strains had been isolated from cattle at an abattoir (190), milk of agalactic cows (seven) and from aborted bovine fetuses (56). Two distinct genome types, Hardjoprajitno and Hardjobovis, were detected. The majority (91 per cent) of isolates from abattoir cattle were of the Hardjobovis type while most (76 per cent) of the isolates from clinical/pathological material were similar to Hardjoprajitno. AD - Veterinary Research Laboratories, Stormont, Belfast. PMID- 2841734 CU - 93 SO - Res Vet Sci 1988 May;44(3):375-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 88278556 AU - Grant GH AU - Smith G AU - Schloss W TI - Seroprevalence of leptospiral antibodies in the Jamaican livestock population. LA - Eng MH - Agglutination Tests MH - Animal MH - *Animals, Domestic MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - Goats MH - Human MH - Jamaica MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880818 DP - 1988 Apr 23 IS - 0042-4900 TA - Vet Rec PG - 419-20 SB - M CY - ENGLAND IP - 17 VI - 122 JC - XBS EM - 8810 AD - Veterinary Diagnostic Laboratory, Hope Gardens, Kingston, Jamaica. PMID- 3394229 CU - 91 SO - Vet Rec 1988 Apr 23;122(17):419-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 88301849 AU - Bourdais A AU - Lonjon B AU - Vergez-Pascal R AU - Fournier A AU - Ah Lo W TI - [Respiratory complications of leptospirosis. Apropos of 6 cases, 3 of which show hemodynamic studies] LA - Fre MH - Adult MH - Case Report MH - Diagnosis, Differential MH - English Abstract MH - Female MH - Hemodynamics MH - Human MH - Male MH - Middle Age MH - Pneumonia/etiology MH - Pulmonary Edema/etiology MH - Respiratory Distress Syndrome, Adult/etiology/physiopathology MH - Respiratory Tract Infections/*etiology/physiopathology/radiography MH - Tuberculosis, Miliary/radiography MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 880916 DP - 1988 Apr-Jun IS - 0025-682X TA - Med Trop (Mars) PG - 149-60 SB - M CY - FRANCE IP - 2 VI - 48 JC - MHQ AA - Author EM - 8811 AB - Six cases of leptospirosis with pulmonary complications are reported. Three cases were accompanying an hepato-nephritis due to L. icterohaemorrhagiae. The first patient died with massive hemoptysis. The second, presenting a bilateral pneumopathy predominant on the left side, recovered after plasma exchange and hemofiltration. The third case concerned a pulmonary edema complicating a vascular refilling in a shock syndrome it simply recovered. The three other cases were observed in an anicteric leptospirosis: in two cases, L. Australis was responsible; in the last, L. icterohaemorrhagiae was involved. The first patient had a radiologic picture simulating miliary tuberculosis. The second had pulmonary edema complicating a vascular refilling in a shock syndrome. The last was an acute respiratory distress syndrome, treated with artificial ventilation with penicillin therapy and corticotherapy. All these 3 patients recovered. The diagnostic, physiopathologic and therapeutic problems of these pulmonary complications of leptospirosis are discussed. The lesional nature of the pulmonary edema is proved by the low pulmonary wedge pressures observed with the Swan-Ganz Catheter. AD - Hopitaux des Armees. PMID- 3405072 TT - Complications respiratoires des leptospiroses. A propos de 6 cas dont trois avec etude hemodynamique. EA - A SO - Med Trop (Mars) 1988 Apr-Jun;48(2):149-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 88301494 AU - Behrens-Baumann W AU - Ecker S AU - Vogel M AU - Ritter K TI - [The so-called "ocular histoplasmosis syndrome"] LA - Ger MH - Adult MH - Chorioretinitis/*pathology MH - Choroid/pathology MH - English Abstract MH - Female MH - Fluorescein Angiography MH - Histoplasmin/diagnostic use MH - Histoplasmosis/*pathology MH - Human MH - Intradermal Tests MH - Male MH - Middle Age MH - *Ophthalmoscopy MH - Retina/pathology MH - Syndrome RN - 9008-05-3 (Histoplasmin) PT - JOURNAL ARTICLE DA - 880920 DP - 1988 Apr IS - 0023-2165 TA - Klin Monatsbl Augenheilkd PG - 348-53 SB - M CY - GERMANY, WEST IP - 4 VI - 192 JC - KWA AA - Author EM - 8811 AB - The authors describe seven patients presenting with ophthalmoscopic findings typical of "presumed ocular histoplasmosis syndrome." However, no humoral antibodies could be demonstrated. Moreover, the results of skin tests were all negative even after "boostering." Hence, the diagnosis of ocular histoplasmosis had to be ruled out. Tests for listeriosis, lues, leptospirosis, ornithosis, Toxocara canis, toxoplasmosis, Larva migrans, and Candida albicans were also negative. There are evidently other, so far unknown, agents which lead to an ophthalmoscopic picture that mimics ocular histoplasmosis with its typical "punched-out lesions" and central hemorrhagic chorioretinopathy. One of these agents may be Epstein-Barr virus, because two of six patients had increased antibody levels of Epstein- Barr nuclear antigen and early antigen, indicating an active or persistent state of viral infection. AD - Univ.-Augenklinik Gottingen. PMID- 3404947 CU - 90 TT - Untersuchungen zum sogenannten "okularen Histoplasmose-Syndrom". EA - A SO - Klin Monatsbl Augenheilkd 1988 Apr;192(4):348-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 88230722 AU - Everard CO AU - Carrington D AU - Korver H AU - Everard JD TI - Leptospires in the marine toad (Bufo marinus) on Barbados. LA - Eng MH - Agglutination Tests MH - Animal MH - Barbados MH - Bufonidae/*microbiology MH - *Disease Reservoirs MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/*transmission MH - Serotyping MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 880629 DP - 1988 Apr IS - 0090-3558 TA - J Wildl Dis PG - 334-8 SB - M CY - UNITED STATES IP - 2 VI - 24 JC - KEM AA - Author EM - 8809 AB - Leptospires were isolated from the kidneys of four of 211 toads (Bufo marinus) caught on Barbados. Two of the isolates were identified as Leptospira interrogans serovar bim in the Autumnalis serogroup (the most common cause of leptospiral illness on Barbados), and two as possibly new serovars in the Australis serogroup. Sera from 198 of the toads were examined by the leptospire microscopic agglutination test. Forty-two (21%) were positive at titers of greater than or equal to 1:100, and 54 (27%) at greater than or equal to 1:50. The predominating serogroups were Australis (50%), Autumnalis (23%) and Panama (13%). The agglutination tests on the culture-positive toads showed that serologic studies alone may be of limited value in these animals. Bufo marinus can harbor pathogenic leptospires, and it may be a significant source of the Autumnalis serogroup infections in the Caribbean. AD - MRC/Barbados Government Leptospira Laboratory, Lower Collymore Rock, Bridgetown. PMID- 3373639 SO - J Wildl Dis 1988 Apr;24(2):334-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 88223046 AU - Prescott JF AU - Nicholson VM TI - Antimicrobial drug susceptibility of Leptospira interrogans serovar hardjo isolated from cattle. LA - Eng MH - Animal MH - Antibiotics/*pharmacology MH - Cattle/*microbiology MH - In Vitro MH - Leptospira interrogans/*drug effects MH - Microbial Sensitivity Tests MH - Sulfamethazine/pharmacology MH - Support, Non-U.S. Gov't RN - 0 (Antibiotics) RN - 57-68-1 (Sulfamethazine) PT - JOURNAL ARTICLE DA - 880711 DP - 1988 Apr IS - 0830-9000 TA - Can J Vet Res PG - 286-7 SB - M CY - CANADA IP - 2 VI - 52 JC - CKL AA - Author EM - 8809 AB - The susceptibility to commonly used drugs of 18 isolates of Leptospira hardjo from the kidneys of feedlot cattle from different sources was determined quantitatively. All isolates were susceptible to penicillin G, ampicillin, tetracycline, erythromycin and streptomycin. Susceptibility to sulphamethazine was ambiguous. No drug resistance was detected and the results were similar to those described for other serovars. AD - Department of Veterinary Microbiology and Immunology, Ontario Veterinary College, University of Guelph. PMID- 3370565 CU - 91 SO - Can J Vet Res 1988 Apr;52(2):286-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 88223033 AU - Prescott JF AU - Miller RB AU - Nicholson VM AU - Martin SW AU - Lesnick T TI - Seroprevalence and association with abortion of leptospirosis in cattle in Ontario. LA - Eng MH - Abortion, Veterinary/*epidemiology/immunology/microbiology MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*epidemiology/immunology/microbiology MH - Female MH - Leptospira interrogans/classification/*immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Ontario MH - Pregnancy MH - Serotyping/veterinary MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880711 DP - 1988 Apr IS - 0830-9000 TA - Can J Vet Res PG - 210-5 SB - M CY - CANADA IP - 2 VI - 52 JC - CKL AA - Author EM - 8809 AB - Sera were collected using a systematic random sampling from 348 cattle herds in Ontario, in proportion to the cattle population in different areas. One cow in five from 296 dairy herds and one in three from 52 beef herds were sampled. The sera were analyzed for prevalence of antibodies to Leptospira interrogans serovar grippotyphosa, hardjo, icterohaemorhagiae and pomona using the microscopic agglutination test. Herd seroprevalence (one or more animals with titer greater than or equal to 80) in beef and dairy herds combined was grippotyphosa 2%, hardjo 13.8%, icterohaemorrhagiae 10.1% and pomona 25.8%; 39% of all herds showed evidence of leptospiral infection with one or more serovars; 44.2% of 52 beef herds had serological evidence of infection with serovar hardjo compared to 8.4% of 296 dairy herds (P less than 0.0001). Seroprevalence of other serovars was not significantly different between beef and dairy herds. The proportion of beef animals seropositive for hardjo and for pomona increased with age, particularly for hardjo; 26.5% of beef animals aged nine years or over were seropositive for hardjo. Dairy animals showed a significant rise of hardjo but not pomona titers with age. The seroprevalence of pomona infection was significantly higher in dairy cattle in eastern Ontario than in other regions. Thirty-four (6.1%) of 553 aborted bovine fetuses had leptospires detected by immunofluorescence techniques. Sixty-five percent of these fetuses were from submissions made between November and January. Leptospires were identified as serovar hardjo by specific immunofluorescence. There appeared, however, to be a paradoxical serological response in that eight aborting cows had antibody titers to pomona rather than hardjo.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Veterinary Micribiology and Immunology, Ontario Veterinary College, University of Guelph. PMID- 3370556 CU - 91 SO - Can J Vet Res 1988 Apr;52(2):210-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 88185438 AU - Bahaman AR AU - Ibrahim AL AU - Stallman ND AU - Tinniswood RD TI - The bacteriological prevalence of leptospiral infection in cattle and buffaloes in West Malaysia. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacteriuria/microbiology/veterinary MH - *Buffaloes MH - Cattle MH - Cattle Diseases/*epidemiology/microbiology MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Malaysia MH - Weil's Disease/epidemiology/microbiology/veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880526 DP - 1988 Apr IS - 0950-2688 TA - Epidemiol Infect PG - 239-46 SB - M CY - ENGLAND IP - 2 VI - 100 JC - EPI AA - Author EM - 8807 AB - A cross-sectional bacteriological survey of cattle in West Malaysia revealed 14.4% (32/222) had leptospiral infection. Isolates were obtained from all except one herd with prevalence of infection in herds ranging from 0-44.8%. A small number of buffalo urine samples were examined and all of them were found to be negative. A leptospiral isolate obtained from a bovine kidney proved to be a new serovar of Leptospira interrogans and the name unipertama was assigned to it. Six other leptospiral serovars were isolated, namely canicola, australis, javanica, ballum, pomona and hardjo. All six serovars were isolated for the first time in cattle in Malaysia. Cattle in Malaysia appear to be the maintenance host for serovar hardjo. The presence of the other serovars in cattle was probably due to contact with the maintenance hosts, pigs for serovar pomona and rodents for the other three serovars. It appears that the epidemiology of leptospiral infection in cattle in Malaysia is similar to that reported overseas. AD - Faculty of Veterinary Medicine and Animal Science, Universiti Pertanian, Malaysia, Selangor. PMID- 3356222 CU - 91 SO - Epidemiol Infect 1988 Apr;100(2):239-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 88154629 AU - Watt G AU - Alquiza LM AU - Padre LP AU - Tuazon ML AU - Laughlin LW TI - The rapid diagnosis of leptospirosis: a prospective comparison of the dot enzyme-linked immunosorbent assay and the genus-specific microscopic agglutination test at different stages of illness. LA - Eng MH - Agglutination Tests MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - Serodiagnosis MH - Support, U.S. Gov't, Non-P.H.S. MH - Time Factors PT - JOURNAL ARTICLE DA - 880421 DP - 1988 Apr IS - 0022-1899 TA - J Infect Dis PG - 840-2 SB - A SB - M CY - UNITED STATES IP - 4 VI - 157 JC - IH3 EM - 8806 AD - U.S. Naval Medical Research Unit Number 2, Manila, Philippines. PMID- 3346574 CU - 90 SO - J Infect Dis 1988 Apr;157(4):840-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 88188192 AU - Chapman AJ AU - Adler B AU - Faine S TI - Antigens recognised by the human immune response to infection with Leptospira interrogans serovar hardjo. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*biosynthesis MH - Antigens, Bacterial/*analysis/immunology MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel MH - Human MH - IgG/biosynthesis MH - IgM/biosynthesis MH - Immunoassay MH - Immunoenzyme Techniques MH - Leptospira interrogans/*immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/diagnosis/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 880518 DP - 1988 Apr IS - 0022-2615 TA - J Med Microbiol PG - 269-78 SB - M CY - ENGLAND IP - 4 VI - 25 JC - J2N AA - Author EM - 8807 AB - Serum samples from patients infected with Leptospira interrogans serovar hardjo were tested by the microscopic agglutination test (MAT), enzyme immunoassay (EIA) and immunoblotting. There was no apparent correlation between MAT titre and EIA optical density (OD) for individual serum samples, but sequential serum samples produced similar profiles in both tests during the course of an infection. Immunoblotting of hardjo sonicate with patients' sera revealed reactions with a number of bands, in the mol. wt (10(3] range 14.4-95. However, all serum samples reacted with the major 28 x 10(3)-mol. wt sub-unit of hardjo lipopolysaccharide (LPS) and most reacted with a (34.5-35) x 10(3)-mol. wt flagella doublet. Examination of sequential serum samples obtained over a period of about 3 months after infection revealed little change in the antigens detected after the second to third week of infection. Absorption of patients' sera with whole viable leptospires revealed that antibodies to several exposed antigens, including LPS, were produced. Sera which reacted with hardjo flagella also reacted with bands of similar mol. wts in preparations from other serovars. AD - Department of Microbiology, Monash University, Clayton, Australia. PMID- 3282073 CU - 91 SO - J Med Microbiol 1988 Apr;25(4):269-78 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 89043118 AU - de Souza D TI - [Human leptospirosis--the infection in the inhabitants of the Aricanduva River valley, Sao Paulo city, 1984-1985. I. Aspects of the group studied and of the environment] LA - Por MH - Animal MH - Brazil MH - Disease Vectors MH - English Abstract MH - *Environmental Health MH - Female MH - Fresh Water MH - Human MH - Leptospirosis/*epidemiology/transmission MH - Male MH - Sex Factors MH - Socioeconomic Factors MH - *Urban Population PT - JOURNAL ARTICLE DA - 881222 DP - 1988 Apr IS - 0080-6234 TA - Rev Esc Enferm USP PG - 103-21 SB - N CY - BRAZIL IP - 1 VI - 22 JC - RSS EM - 8902 PMID- 3187134 CU - 90 LI - N TT - Leptospirose humana--infeccao em habitantes do Vale do Rio Aricanduva, municipio de Sao Paulo, 1984-1985. Parte I--aspectos relativos ao grupo estudado e ao meio ambiente. EA - A SO - Rev Esc Enferm USP 1988 Apr;22(1):103-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 89096397 AU - Palmer MF TI - Laboratory diagnosis of leptospirosis. LA - Eng MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis/microbiology MH - Serodiagnosis PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 890213 DP - 1988 Apr IS - 0308-3616 TA - Med Lab Sci PG - 174-8 CY - ENGLAND IP - 2 VI - 45 JC - MA5 EM - 8904 RF - 29 PMID- 3062306 CU - 90 SO - Med Lab Sci 1988 Apr;45(2):174-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 88301281 AU - Hata K AU - Yamaguchi T AU - Ono E AU - Yanagawa R TI - Comparative study of leptospiral strains Ictero No. I and RGA by restriction endonuclease DNA analysis. LA - Eng MH - Comparative Study MH - *DNA Restriction Enzymes MH - *DNA, Bacterial MH - Electrophoresis, Agar Gel MH - Leptospira/*genetics MH - Serotyping MH - Species Specificity RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 880912 DP - 1988 Apr IS - 0047-1917 TA - Jpn J Vet Res PG - 133-6 CY - JAPAN IP - 2 VI - 36 JC - KRG EM - 8811 PMID- 2841529 CU - 93 SO - Jpn J Vet Res 1988 Apr;36(2):133-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 88230714 AU - McCue PM AU - O'Farrell TP TI - Serological survey for selected diseases in the endangered San Joaquin kit fox (Vulpes macrotis mutica). LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - Brucellosis/immunology/veterinary MH - California MH - Coccidioidomycosis/immunology/veterinary MH - Distemper Virus, Canine/immunology MH - Foxes/*blood MH - Hepatitis Antibodies/analysis MH - Hepatitis, Infectious Canine/immunology MH - Leptospirosis/immunology/veterinary MH - Parvoviridae Infections/immunology/veterinary MH - Plague/immunology/veterinary MH - Support, U.S. Gov't, Non-P.H.S. MH - Toxoplasmosis, Animal/immunology MH - Tularemia/immunology/veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) RN - 0 (Hepatitis Antibodies) PT - JOURNAL ARTICLE DA - 880629 DP - 1988 Apr IS - 0090-3558 TA - J Wildl Dis PG - 274-81 SB - M CY - UNITED STATES IP - 2 VI - 24 JC - KEM AA - Author EM - 8809 AB - Blood from endangered San Joaquin kit foxes (Vulpes macrotis mutica) inhabiting the Elk Hills Naval Petroleum Reserve, Kern County, and the Elkhorn Plain, San Luis Obispo County, California, was collected in 1981, 1982 and 1984 and sera were tested for antibodies against 10 selected pathogens. Proportions of kit fox sera containing antibodies against pathogens were: canine parvovirus, 100% in 1981-1982 and 67% in 1984; infectious canine hepatitis virus, 6% in 1981-1982 and 21% in 1984; canine distemper virus, none in 1981-1982 and 14% in 1984; Francisella tularensis, 8% in 1981-1982 and 31% in 1984; Brucella abortus, 8% in 1981-1982 and 3% in 1984; Brucella canis, 14% in 1981- 1982 and none in 1984; Toxoplasma gondii, 6% in 1981-1982; Coccidioides immitis, 3% in 1981-1982; and Yersinia pestis and Leptospira interrogans serotypes canicola, grippotyphosa, hardjo, icterohaemorrhagiae, and pomona, none in 1981-1982. Although antibodies against selected pathogens were present, no clinical indications of disease were observed in these fox populations. AD - EG&G Energy Measurements, Inc., Santa Barbara Operations, Goleta, California 93117. PMID- 2836636 CU - 93 SO - J Wildl Dis 1988 Apr;24(2):274-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 88293330 AU - Skilbeck NW AU - Forsyth WM AU - Dohnt M TI - Bovine leptospirosis: microbiological and histological findings in cattle at slaughter [published erratum appears in Aust Vet J 1988 May;65(5):164] LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology/pathology MH - Kidney Diseases/microbiology/pathology/*veterinary MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 880907 DP - 1988 Mar IS - 0005-0423 TA - Aust Vet J PG - 73-5 SB - M CY - AUSTRALIA IP - 3 VI - 65 JC - 9IE AA - Author EM - 8811 AB - Kidneys from cattle at slaughter were examined for the presence of leptospires. Of 218 (8.3%) kidneys leptospires were isolated from 18; all were identified as Leptospira interrogans serovar hardjo. None of the leptospire-infected kidneys had histopathological lesions indicative of leptospirosis and leptospires were demonstrated in only 2 by immunogold silver staining. Leptospires infected kidneys remained viable for at least 21 days when stored at 4 degrees but became non- viable within 14 days when stored frozen at -15 degrees. AD - Victorian Department of Agriculture. RO - M:MWS RO - M:MWS PMID- 3401146 LR - 881219 SO - Aust Vet J 1988 Mar;65(3):73-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 88266415 AU - Semenovich VN AU - Polotskii IuE AU - Daiter AB AU - Kleinerman AS TI - [Characteristics of the interaction of Leptospira with the host organism in the infectious process in golden hamsters] LA - Rus MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacterial Adhesion MH - Comparative Study MH - English Abstract MH - Guinea Pigs MH - Hamsters MH - Kidney/microbiology MH - Leptospira/immunology/*pathogenicity MH - Leptospira canicola/immunology/pathogenicity MH - Leptospira interrogans/immunology/pathogenicity MH - Leptospirosis/*etiology/immunology/microbiology MH - Liver/microbiology MH - Mesocricetus MH - Time Factors MH - Virulence RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880802 DP - 1988 Mar IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 76-82 SB - M CY - USSR IP - 3 JC - Y9O AA - Author EM - 8810 AB - The comparative evaluation of the interaction of L. icterohaemorrhagiae strain P, L. canicola strain CL and L. hebdomadis strain 650 with golden hamster liver and kidney cells is presented. Three variants of the course of Leptospira infection have been distinguished: (1) the hepato-renal (icteric) variant, caused by the adhesion of leptospires to liver cells with the colonization of their surface and the disaggregation of liver-cell complexes and by the accumulation of leptospires in the kidney interstice; as a consequence, parenchymatous hepatitis and nephroso-nephritis develop, which lead to the death of animals; (2) the renal (anicteric) variant, characterized by the absence of the infective agent and lesions in the liver, by adhesion of leptospires to and their colonization of the nephrothelium of the proximal convoluted tubules of the kidneys; in this case some of the animals die because of renal insufficiency and shock, while in the surviving animals prolonged carrier state develops; (3) the intermediate variant, characterized by the initial process of leptospiral adhesion and colonization in the liver and its subsequent progress in the kidneys. PMID- 3389008 CU - 91 TT - Osobennosti vzaimodeistviia leptospir s organizmom khoziaina pri infektsionnom protsesse u zolotistykh khomiakov. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1988 Mar;(3):76-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 88185462 AU - Ciceroni L AU - Pinto A AU - Cacciapuoti B TI - Recent trends in human leptospirosis in Italy. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Female MH - Human MH - Italy MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Seasons MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 880526 DP - 1988 Mar IS - 0392-2990 TA - Eur J Epidemiol PG - 49-54 SB - M CY - ITALY IP - 1 VI - 4 JC - ERE AA - Author EM - 8807 AB - The recent epidemiological trends of human leptospirosis in Italy were investigated using data collected for the years 1981-1985. A total of 626 hospitalized patients with clinical diagnoses of suspected leptospirosis were reported by hospital centers from several Italian regions. Epidemiological, clinical and seroimmunological data were collected in 517 of these cases and examined by the National Center for Leptospirosis. Serological findings in 33.5% of these subjects met the criteria for confirmation of the disease. In 21.8% of the subjects, low titer antibodies were detected, which possibly reflected previous leptospiral infections. An early antibiotic treatment of the current infection may also have lowered the seroimmunological response in some of these patients. In 59.3% of the confirmed cases, modes of transmission were allotted equally between accidental events and recreational or occupational activities. Drinking water from an open air fountain emerged as an uncommon mode of transmission; it was responsible for an outbreak of 33 cases of leptospirosis. In another 37.07% of the subjects, it was impossible to establish the mode of transmission. Respiratory or influenza-like symptoms were the only clinical signs of illness in 21.2% of the patients with confirmed leptospirosis. In comparison to the sixties and seventies, the prevalence of infecting serovars showed increasing incidence of infections due to serovars of the Javanica (11.0%) and Australis (11.0%) serogroups and an important decrease in the Bataviae serogroup infections (from 58.8% in rice-field workers in the forties to 0.6% in the years 1981-1985). Sejroe serogroup infections accounted for 4.5 per cent of confirmed cases of leptospirosis.(ABSTRACT TRUNCATED AT 250 WORDS) AD - Department of Medical Bacteriology and Mycology, Istituto Superiore di Sanita, Roma, Italy. PMID- 3356234 CU - 88 SO - Eur J Epidemiol 1988 Mar;4(1):49-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 89072421 AU - da Silva MV AU - Camargo ED AU - Vaz AJ AU - de Souza AM AU - Ueda M AU - Sakata EE TI - [Immunoenzymatic test (ELISA) in detecting circulating antibodies of the IgM class in human leptospirosis] LA - Por MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - English Abstract MH - *Enzyme-Linked Immunosorbent Assay MH - Hemagglutination Tests MH - Human MH - IgM/*analysis MH - Leptospirosis/*diagnosis/immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890125 DP - 1988 Mar-Apr IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 95-100 CY - BRAZIL IP - 2 VI - 30 JC - S9D EM - 8903 PMID- 3201066 CU - 91 TT - Teste imunoenzimatico (ELISA) para deteccao de anticorpos circulantes da classe IgM na leptospirose humana. EA - A SO - Rev Inst Med Trop Sao Paulo 1988 Mar-Apr;30(2):95-100 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 89072420 AU - Girio RJ AU - Mathias LA TI - Use of saprophytic Leptospira strains in the serodiagnosis of experimental leptospirosis in guinea-pigs (Cavia sp). LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Formation MH - Antigens, Bacterial/*immunology MH - Cross Reactions MH - Guinea Pigs MH - Leptospira interrogans/*immunology MH - Leptospirosis/*diagnosis MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 890125 DP - 1988 Mar-Apr IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 91-4 CY - BRAZIL IP - 2 VI - 30 JC - S9D EM - 8903 PMID- 3201065 CU - 91 SO - Rev Inst Med Trop Sao Paulo 1988 Mar-Apr;30(2):91-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 89036112 AU - Van Eys GJ AU - Zaal J AU - Schoone GJ AU - Terpstra WJ TI - DNA hybridization with hardjobovis-specific recombinant probes as a method for type discrimination of Leptospira interrogans serovar hardjo. LA - Eng MH - Chromosome Mapping MH - Cloning, Molecular MH - *DNA Probes MH - *DNA, Bacterial MH - Leptospira interrogans/*classification MH - Nucleic Acid Hybridization MH - Restriction Mapping RN - 0 (DNA Probes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 881202 DP - 1988 Mar IS - 0022-1287 TA - J Gen Microbiol PG - 567-74 SB - M CY - ENGLAND VI - 134 ( Pt 3) JC - I87 AA - Author EM - 8902 AB - Restriction endonuclease analysis of DNA of Leptospira interrogans, serovar hardjo, showed two distinct types within this serovar. These two types, hardjoprajitno and hardjobovis, cannot be differentiated by monoclonal antibodies. Application of 32P- or biotin-labelled total DNA probes in dot-blot or in situ hybridization assays showed a high sensitivity of the assays but also considerable cross-hybridization. Therefore, a genomic library of hardjobovis was constructed and a number of hardjobovis-specific recombinant clones were isolated. Finally, four clones were selected on the basis of a strong hybridization signal and a high specificity for hardjobovis as compared to hardjoprajitno. In a dot-blot assay as well as in in situ hybridization experiments all four clones gave strong signals, and no cross-hybridization with hardjoprajitno was observed in either type of assay. Our results indicate that specific recombinant DNA probes might provide tools for routine diagnosis and classification in cases of hardjo infections. AD - N. H. Swellengrebel Laboratory of Tropical Hygiene, Royal Tropical Institute, Amsterdam, The Netherlands. PMID- 3183617 CU - 92 SO - J Gen Microbiol 1988 Mar;134 ( Pt 3):567-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 89016938 AU - Gilks CF AU - Lambert HP AU - Broughton ES AU - Baker CC TI - Failure of penicillin prophylaxis in laboratory acquired leptospirosis. LA - Eng MH - Accidents, Occupational MH - Adult MH - Case Report MH - Doxycycline/therapeutic use MH - Female MH - Human MH - Laboratory Infection/*prevention & control MH - Leptospira interrogans MH - Leptospirosis/*prevention & control MH - Penicillin G/*therapeutic use MH - Penicillin Resistance RN - 564-25-0 (Doxycycline) RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 881123 DP - 1988 Mar IS - 0032-5473 TA - Postgrad Med J PG - 236-8 SB - M CY - ENGLAND IP - 749 VI - 64 JC - PFX AA - Author EM - 8901 AB - A laboratory technician developed leptospirosis following accidental inoculation, despite prompt administration of parenteral penicillin by an accepted regimen of post-exposure prophylaxis. Another technician was similarly exposed and was given doxycycline; no illness or serological conversion followed. The implications of these cases are discussed and recommendations made for post-exposure chemoprophylaxis with doxycycline. AD - St. George's Hospital, London, UK. PMID- 3174544 SO - Postgrad Med J 1988 Mar;64(749):236-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 88239639 AU - Stamm LV AU - Charon NW TI - Sensitivity of pathogenic and free-living Leptospira spp. to UV radiation and mitomycin C. LA - Eng MH - Comparative Study MH - Dose-Response Relationship, Radiation MH - Drug Resistance, Microbial MH - Fresh Water MH - Leptospira/drug effects/growth & development/*radiation effects MH - Leptospira interrogans/drug effects/growth & development/radiation effects MH - Mitomycins/*pharmacology MH - Species Specificity MH - Support, U.S. Gov't, P.H.S. MH - *Ultraviolet Rays MH - Water Microbiology RN - 0 (Mitomycins) RN - 50-07-7 (Mitomycin C) PT - JOURNAL ARTICLE ID - S07-RR05433/RR/NCRR ID - DE04645/DE/NIDR DA - 880708 DP - 1988 Mar IS - 0099-2240 TA - Appl Environ Microbiol PG - 728-33 SB - M CY - UNITED STATES IP - 3 VI - 54 JC - 6K6 AA - Author EM - 8809 AB - The habitats for the two major Leptospira spp. differ. The main habitat of L. biflexa is soil and water, whereas L. interrogans primarily resides in the renal tubules of animals. We investigated whether these two species, along with L. illini (species incertae sedis), differ with respect to their sensitivity to UV radiation. The doses of UV resulting in 37, 10, and 1% survival were determined for representative serovars from each species. L. interrogans serovar pomona was 3.0 to 4.8 times more sensitive to UV than the other Leptospira species under the 37, 10, and 1% survival parameters. In comparison to other bacteria, L. interrogans serovar pomona is among the most sensitive to UV. In a qualitative UV sensitivity assay, L. interrogans serovars were found to be in general more sensitive than L. biflexa serovars. All three species were found to have a photoreactivation DNA repair mechanism. Since organisms that are resistant to UV are often resistant to the DNA cross-linking agent mitomycin C, we tested the relative sensitivity of several Leptospira serovars to this compound. With few exceptions, L. biflexa and L. illini serovars were considerably more resistant to mitomycin C than the L. interrogans serovars. The mitomycin C sensitivity assay could be a useful addition to current characterization tests used to differentiate the Leptospira species. AD - Department of Microbiology, School of Medicine, West Virginia University, Morgantown 26506. PMID- 3132098 CU - 96 SO - Appl Environ Microbiol 1988 Mar;54(3):728-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 88236551 AU - Elliott KG TI - A simple step to enhance the demonstration of Leptospira in Young's Warthin-Starry technique. LA - Eng MH - Animal MH - Kidney/microbiology MH - Leptospira/*cytology MH - Leptospirosis/microbiology MH - Staining/*methods MH - Swine PT - JOURNAL ARTICLE DA - 880711 DP - 1988 Mar IS - 0038-9153 TA - Stain Technol PG - 122-4 SB - M CY - UNITED STATES IP - 2 VI - 63 JC - V06 EM - 8809 AD - Animal Health Laboratories, Department of Agriculture, South Perth, Western Australia. PMID- 2453950 CU - 95 SO - Stain Technol 1988 Mar;63(2):122-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 88142198 AU - Watt G AU - Padre LP AU - Tuazon ML AU - Calubaquib C AU - Santiago E AU - Ranoa CP AU - Laughlin LW TI - Placebo-controlled trial of intravenous penicillin for severe and late leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Clinical Trials MH - Double-Blind Method MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Human MH - IgM/analysis MH - Infusions, Intravenous MH - Male MH - Penicillin G/administration & dosage/*therapeutic use MH - Random Allocation MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Weil's Disease/*drug therapy/immunology RN - 61-33-6 (Penicillin G) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - RANDOMIZED CONTROLLED TRIAL DA - 880401 DP - 1988 Feb 27 IS - 0140-6736 TA - Lancet PG - 433-5 SB - A SB - M SB - X CY - ENGLAND IP - 8583 VI - 1 JC - L0S AA - Author EM - 8806 AB - The effect of a 7-day course of intravenous penicillin (6 million units/day) on severe, advanced leptospirosis was examined in a randomised, placebo-controlled, double-blind trial involving 42 patients. Every measurable aspect of the disease was favourably affected by penicillin. Fever lasted more than twice as long in the placebo group (11.6 [SD 8.34] days vs 4.7 [4.19] days, p less than 0.005), and by the fourth day after starting penicillin more than half the treatment group, but only 1 of 19 in the placebo group, were afebrile (p less than 0.005). Creatinine rises persisted more than thrice as long in the patients receiving only placebo (8.3 [8.46] days vs 2.7 [1.90] days; p less than 0.01). Penicillin also shortened the hospital stay and prevented leptospiruria. Intravenous penicillin should be given to patients with severe leptospirosis, even if therapy can be begun only late in the course of their disease. AD - US Naval Medical Research Unit 2, Manila, Philippines. RO - M:MWS PMID- 2893865 LR - 900109 CU - 94 SO - Lancet 1988 Feb 27;1(8583):433-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 88337941 AU - Zamora J AU - Riedemann S AU - Frias M TI - [Swine leptospirosis. First isolation in Chile of Leptospira interrogans serovar tarassovi] LA - Spa MH - Abattoirs MH - Animal MH - Chile MH - English Abstract MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 881017 DP - 1988 Feb IS - 0931-1793 TA - Zentralbl Veterinarmed [B] PG - 105-8 CY - GERMANY, WEST IP - 2 VI - 35 JC - Y72 EM - 8812 PMID- 3420981 TT - Leptospirosis porcina. Primer aislamiento en Chile de Leptospira interrogans serovar tarassovi. EA - A SO - Zentralbl Veterinarmed [B] 1988 Feb;35(2):105-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 88295991 AU - Zhang SM TI - [Cytological examination of the CSF in leptospiral cerebral arteritis] LA - Chi MH - Adult MH - Cerebral Arteries MH - Cerebrospinal Fluid/*cytology MH - Child MH - English Abstract MH - Human MH - IgA/cerebrospinal fluid MH - IgM/cerebrospinal fluid MH - Leptospirosis/*cerebrospinal fluid/pathology PT - JOURNAL ARTICLE DA - 880915 DP - 1988 Feb IS - 0412-4057 TA - Chung Hua Shen Ching Ching Shen Ko Tsa Chih PG - 53-6, 64 CY - CHINA IP - 1 VI - 21 JC - D7Y EM - 8811 PMID- 3402277 EA - A SO - Chung Hua Shen Ching Ching Shen Ko Tsa Chih 1988 Feb;21(1):53-6, 64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 88253378 AU - Zhang FZ TI - [Distribution and dynamics of leptospiral serovars on the frontier of Yunnan Province] LA - Chi MH - China MH - English Abstract MH - Human MH - Leptospira/*classification MH - Leptospira canicola/classification MH - Leptospira interrogans/classification MH - Serotyping PT - JOURNAL ARTICLE DA - 880811 DP - 1988 Feb IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 25-8 CY - CHINA IP - 1 VI - 9 JC - CQG EM - 8810 PMID- 3383231 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1988 Feb;9(1):25-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 88237208 AU - Takase H AU - Yanagawa R TI - Opsonic effect of monoclonal antibodies against Leptospira interrogans serovar copenhageni. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Monoclonal/*immunology MH - Complement/immunology MH - Enzyme-Linked Immunosorbent Assay MH - Hybridomas MH - IgG/immunology MH - Leptospira interrogans/*immunology/ultrastructure MH - Macrophages/immunology/ultrastructure MH - Mice MH - Mice, Inbred BALB C MH - Microscopy, Electron MH - Opsonins/*immunology RN - 0 (Antibodies, Monoclonal) RN - 0 (Opsonins) RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 880628 DP - 1988 Feb IS - 0378-1135 TA - Vet Microbiol PG - 167-80 SB - M CY - NETHERLANDS IP - 2 VI - 16 JC - XBW AA - Author EM - 8809 AB - The opsonic effect of monoclonal antibodies (McAbs) against Leptospira interrogans serovar copenhageni strain Shibaura was examined in vitro using radiolabeled organisms and mouse peritoneal exudate macrophages. Four IgG McAbs (all IgG3) and 2 IgM McAbs were used, all showed different reactivities and were bound to homologous lipopolysaccharide (LPS). IgG3 McAbs at the sub-agglutinating concentration were opsonic, but the degree of the opsonic effect varied among IgG3 McAbs. Opsonization with IgG3 McAbs at the concentration showing the same level of ELISA binding showed that the highest opsonic effect was exerted by Sw-6 antibody. The other IgG3 McAbs showed a similar but lower opsonic effect. IgM McAbs, which were not opsonic at the sub- agglutinating concentration even in the presence of complement, showed opsonic effect at the agglutinating concentration. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. PMID- 3376416 CU - 92 SO - Vet Microbiol 1988 Feb;16(2):167-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 88231429 AU - Bogolitsin IuG AU - Zhukov VIu AU - Nedashkovskii ZD AU - Agafonov VM AU - Portnov OA TI - [Combined use of extracorporeal detoxication and hyperbaric oxygenation in severe forms of infectious diseases] LA - Rus MH - Adult MH - Botulism/*therapy MH - Case Report MH - Combined Modality Therapy MH - English Abstract MH - Female MH - *Hemoperfusion MH - Hepatitis B/*therapy MH - Human MH - *Hyperbaric Oxygenation MH - Leptospirosis/*therapy MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 880712 DP - 1988 Feb IS - 0023-2149 TA - Klin Med (Mosk) PG - 120-2 CY - USSR IP - 2 VI - 66 JC - KW2 EM - 8809 PMID- 3374034 TT - Sochetannoe primenenie ekstrakorporal'noi detoksikatsii i giperbaricheskoi oksigenatsii pri tiazhelykh formakh infektsionnykh boleznei. EA - A SO - Klin Med (Mosk) 1988 Feb;66(2):120-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 89016917 AU - Harrison NA AU - Fitzgerald WR TI - Leptospirosis--can it be a sexually transmitted disease? LA - Eng MH - Female MH - Human MH - Leptospirosis/*transmission MH - Male MH - Sexual Partners MH - Sexually Transmitted Diseases/*transmission PT - JOURNAL ARTICLE DA - 881122 DP - 1988 Feb IS - 0032-5473 TA - Postgrad Med J PG - 163-4 SB - M CY - ENGLAND IP - 748 VI - 64 JC - PFX AA - Author EM - 8901 AB - Person to person spread of leptospirosis has not been previously reported. We describe two cases occurring in a man and wife which tantalisingly raise this possibility. AD - Renal Unit, Princess Mary's Royal Air Force Hospital, Halton, Aylesbury, Bucks. PMID- 3174532 SO - Postgrad Med J 1988 Feb;64(748):163-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 88242599 AU - Vernet V AU - Garnier JM AU - Masure F AU - Chippaux-Hyppolite C TI - Early recovery of Leptospira icterohaemorrhagiae using a lysis centrifugation blood culture system [letter] LA - Eng MH - Adult MH - Case Report MH - Centrifugation MH - Human MH - Leptospira interrogans/*isolation & purification MH - Male MH - Weil's Disease/*diagnosis PT - LETTER DA - 880726 DP - 1988 Feb IS - 0934-9723 TA - Eur J Clin Microbiol Infect Dis PG - 86-7 SB - M CY - GERMANY, WEST IP - 1 VI - 7 JC - EM5 EM - 8809 PMID- 3132391 CU - 91 SO - Eur J Clin Microbiol Infect Dis 1988 Feb;7(1):86-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 88144315 AU - Routy JP AU - Blanc AP AU - Costello R AU - Eucalipto J AU - Lee Poeyio W AU - Chardon H TI - [Value of intravenous gamma globulins at heavy dose in thrombopenia in a case of leptospirosis (letter)] LA - Fre MH - Adult MH - Case Report MH - Human MH - *Immunization, Passive MH - Injections, Intravenous MH - Male MH - Thrombocytopenia/complications/*therapy MH - Weil's Disease/*complications PT - LETTER DA - 880325 DP - 1988 Jan 9-16 IS - 0755-4982 TA - Presse Med PG - 37 SB - M SB - X CY - FRANCE IP - 1 VI - 17 JC - PMT EM - 8806 PMID- 2964016 CU - 92 TT - Interet des gammaglobulines intraveineuses a forte dose au cours d'une thrombopenie dans un cas de leptospirose. SO - Presse Med 1988 Jan 9-16;17(1):37 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 88327979 AU - Brethes B AU - Puech PL AU - Fraisse A AU - Dubois P AU - Domenech J AU - Bourdin P AU - Moreau JP AU - Capdevielle P AU - Desoutter D AU - Lechapt M AU - et al TI - [Epidemiological study of leptospirosis in New Caledonia] LA - Fre MH - Adult MH - Age Factors MH - Animal MH - English Abstract MH - Female MH - Human MH - Leptospirosis/ethnology/*epidemiology MH - Male MH - Middle Age MH - New Caledonia MH - Occupational Diseases/epidemiology MH - Risk Factors MH - Seasons MH - Sex Factors MH - Weil's Disease/ethnology/*epidemiology PT - JOURNAL ARTICLE DA - 881027 DP - 1988 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 189-97 SB - M CY - FRANCE IP - 2 VI - 81 JC - C4G AA - Author EM - 8812 AB - This epidemiological survey includes the study of human and animal leptospirosis in New Caledonia from clinical cases as well as a systematic serological study about exposed human and animal populations. The results show that this disease is endemic on the whole territory with a few important focuses in agricultural area, especially on the Western coast. Leptospira icterohemorrhagiae is the main serotype and is responsible for serious human leptospirosis. The male farmers constitute the most exposed population, especially from March to May, end of the host season. In order to reduce the importance of this disease, it is desirable that the farmers are vaccinated and mass media campaigns are necessary to improve the prevention. AD - Institut Pasteur de Noumea, Nouvelle-Caledonie. PMID- 3416406 CU - 88 TT - Etude epidemiologique de la leptospirose en Nouvelle-Caledonie. EA - A SO - Bull Soc Pathol Exot Filiales 1988;81(2):189-97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 88285654 AU - Khisamov GZ AU - Morozova NK TI - Fatty acids as resource of carbon for leptospirae. LA - Eng MH - Culture Media MH - Fatty Acids, Nonesterified/*metabolism MH - Kinetics MH - Leptospira/*growth & development MH - Oleic Acids/metabolism RN - 0 (Culture Media) RN - 0 (Fatty Acids, Nonesterified) RN - 0 (Oleic Acids) RN - 112-80-1 (Oleic Acid) PT - JOURNAL ARTICLE DA - 880826 DP - 1988 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 87-93 SB - M CY - CZECHOSLOVAKIA IP - 1 VI - 32 JC - IEV AA - Author EM - 8811 AB - The effect of saturated (palmitic, stearic, myristic) and unsaturated (oleic) fatty acids on the proliferation of Leptospirae was studied. Proliferation of the saprophytic strains G-45, K-1028 (serovar not identified) and of the pathogenic strain VGNKI-3 (serovar canicola) of Leptospirae was obtained on a serum-free medium with the addition of saturated fatty acids. The unsaturated oleic acid at relatively high concentrations (0.5 mg/ml) suppresses proliferation of these spirochetes. It has been demonstrated that the variants used in the experiment can be utilized for the study of nutritional requirements of Leptospirae and their metabolism. AD - Patrice Lumumba University of Friendship of Nations, Moscow, USSR. PMID- 3397533 CU - 96 SO - J Hyg Epidemiol Microbiol Immunol 1988;32(1):87-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 88285653 AU - Volina EG AU - Kiktenko VS AU - Sarukhanova LE AU - Levina LF AU - Arutyunova GA AU - Soboleva GL TI - Investigation of hemolytic activity of leptospirae on solid culture media. LA - Eng MH - Animal MH - Cattle MH - Chickens MH - Comparative Study MH - Culture Media MH - Erythrocytes/cytology MH - Hamsters MH - *Hemolysis MH - Horses MH - Leptospira/growth & development/*pathogenicity MH - Mice MH - Rabbits MH - Rats MH - Sheep MH - Species Specificity RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 880826 DP - 1988 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 79-85 SB - M CY - CZECHOSLOVAKIA IP - 1 VI - 32 JC - IEV AA - Author EM - 8811 AB - Results of investigation of hemolytic activity of leptospirae against red blood cells of various animal species on solid culture media using the technique of agar layers are presented. It has been shown that hemolytic properties of pathogenic and saprophytic leptospirae differ with respect to red blood cells of the sheep, the rabbit, the hamster, the albino rat and the albino mouse. Hemolytic activity of leptospirae regarding the erythrocytes of the cattle, the horse and the fowl depends on the strain of leptospirae. The advantage of using solid nutrient media for the determination of hemolytic properties of leptospirae in comparison with liquid media has been demonstrated. AD - Department of Microbiology, Medical Faculty of the Patrice Lumumba University of Friendship of Peoples, Moscow, USSR. PMID- 3397532 CU - 91 SO - J Hyg Epidemiol Microbiol Immunol 1988;32(1):79-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 88256260 AU - Madhusudhana SN AU - Bhargawa SK TI - Serological survey of leptospirosis in and around Bangalore. LA - Eng MH - Antibodies, Bacterial/analysis MH - Fever of Unknown Origin/etiology MH - Human MH - India MH - Jaundice/etiology MH - Leptospira/immunology MH - Leptospirosis/*epidemiology MH - Occupational Diseases/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880729 DP - 1988 Jan IS - 0377-4929 TA - Indian J Pathol Microbiol PG - 60-3 CY - INDIA IP - 1 VI - 31 JC - GKK EM - 8810 PMID- 3384458 CU - 91 SO - Indian J Pathol Microbiol 1988 Jan;31(1):60-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 88218322 AU - Thoinet S AU - Boucaud Maitre Y AU - Hutinel P AU - Cloppet H AU - Quenin P TI - [Sero-epidemiologic study of 277 cases of human leptospirosis in the central eastern region of France between 1972 and 1984] LA - Fre MH - English Abstract MH - France MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*epidemiology/immunology MH - Mass Screening MH - Weil's Disease/epidemiology/immunology PT - JOURNAL ARTICLE DA - 880622 DP - 1988 IS - 0398-7620 TA - Rev Epidemiol Sante Publique PG - 26-9 SB - M CY - FRANCE IP - 1 VI - 36 JC - RST AA - Author EM - 8808 AB - We reported 277 clinical cases of Leptospirosis with a significant serological title (greater than 100) by lyse-agglutination. Sera were sampled from 1972 to 1984 among 9182 subjects living in Central-Eastern departments of France) for immunological diagnosis of leptospirosis. We noted the stability of the average yearly rate in this region, the difficulty in evaluating the incidence of the disease, the clinical predominance of icterus and the good clinical prognosis with specific antibiotherapy. AD - Hopital Saint-Joseph, Lyon. PMID- 3368606 CU - 88 TT - Etude seroepidemiologique de 277 cas de leptospirose humaine dans le Centre-Est de la France entre 1972 et 1984. EA - A SO - Rev Epidemiol Sante Publique 1988;36(1):26-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 88208906 AU - Mercy AR AU - Peet RL AU - Hustas L TI - Macroscopic kidney lesions in slaughtered pigs as an indicator of current leptospiral infection [letter] LA - Eng MH - Animal MH - Kidney/*pathology MH - Leptospira interrogans MH - Leptospirosis/pathology/*veterinary MH - *Swine MH - Swine Diseases/*pathology PT - LETTER DA - 880531 DP - 1988 Jan IS - 0005-0423 TA - Aust Vet J PG - 35-6 SB - M CY - AUSTRALIA IP - 1 VI - 65 JC - 9IE EM - 8808 PMID- 3365180 CU - 91 SO - Aust Vet J 1988 Jan;65(1):35-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 88172740 AU - Heidt GA AU - Rucker RA AU - Kennedy ML AU - Baeyens ME TI - Hematology, intestinal parasites, and selected disease antibodies from a population of bobcats (Felis rufus) in central Arkansas. LA - Eng MH - Animal MH - Arkansas MH - Carnivora/*blood/immunology/parasitology MH - Feces/parasitology MH - Female MH - Intestinal Diseases, Parasitic/epidemiology/*veterinary MH - Leptospirosis/epidemiology/veterinary MH - Male MH - Parasite Egg Count/veterinary MH - Reference Values MH - Rocky Mountain Spotted Fever/epidemiology/veterinary MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Toxoplasmosis, Animal/epidemiology MH - Tularemia/epidemiology/veterinary PT - JOURNAL ARTICLE DA - 880512 DP - 1988 Jan IS - 0090-3558 TA - J Wildl Dis PG - 180-3 SB - M CY - UNITED STATES IP - 1 VI - 24 JC - KEM AA - Author EM - 8807 AB - Eight bobcats with adjoining or overlapping home ranges were examined. Hematological values were within previously reported ranges. Six bobcats demonstrated antibody titers to Toxoplasma gondii. Isospora spp., Taenia taeniaeformis, Spirometra mansoides, Physoloptera rara, Toxocara cati, Strongyloides spp., Trichurus spp., Capillaria spp., and Ancyclostoma spp. were found also in the animals examined. The mean number of parasite species per host was 4.1. All bobcats tested negative for serum antibodies to Rocky Mountain spotted fever (Rickettsia rickettsii). Two bobcats had titers less than or equal to 1:20 for tularemia (Francisiella tularensis), and two were positive for leptospirosis (Leptospira spp.). AD - Department of Biology, University of Arkansas, Little Rock 72204. PMID- 3352091 CU - 88 SO - J Wildl Dis 1988 Jan;24(1):180-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 88194570 AU - Goldstein SF AU - Charon NW TI - Motility of the spirochete Leptospira. LA - Eng MH - Cell Movement MH - Leptospira/*physiology/ultrastructure MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL ID - DEO4645 DA - 880531 DP - 1988 IS - 0886-1544 TA - Cell Motil Cytoskeleton PG - 101-10 SB - M CY - UNITED STATES IP - 2 VI - 9 JC - CRD AA - Author EM - 8808 AB - Spirochetes are a group of bacteria with a unique ultrastructure and a fascinating swimming behavior. This article reviews the hydrodynamics of spirochete motility, and examines the motility of the spirochete Leptospira in detail. Models of Leptospira motility are discussed, and future experiments are proposed. The outermost structure of Leptospira is a membrane sheath, and within this sheath are a helically shaped cell cylinder and two periplasmic flagella. One periplasmic flagellum is attached subterminally at either end of the cell cylinder and extends partway down the length of the cell. In swimming cells, each end of the cell may assume either a spiral or a hook shape. Translational cells have the anterior end spiral shaped, and the posterior end hook shaped. In the model of Berg et al., the periplasmic flagella are believed to rotate between the sheath and the cell cylinder. Rotation of the anterior periplasmic flagellum causes the generation of a gyrating spiral-shaped wave. This wave is believed sufficient to propel the cells forward in a low-viscosity medium. The cell cylinder concomitantly rolls around the periplasmic flagella in the opposite direction--which allows the cell to literally screw through a gel-like viscous medium without slippage. This model is presented, and it is contrasted to previous models of Leptospira motility. AD - Department of Genetics and Cell Biology, University of Minnesota, St. Paul. RF - 57 PMID- 3282685 CU - 90 SO - Cell Motil Cytoskeleton 1988;9(2):101-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 90047546 AU - Livatino L AU - Livatino L AU - Ignesti C TI - [Results and observations on the research of circulating immunocomplexes in subjects with suspected autoimmune pathology] LA - Ita MH - Antigen-Antibody Complex/*analysis/immunology MH - Autoimmune Diseases/*blood/immunology MH - English Abstract MH - Human RN - 0 (Antigen-Antibody Complex) PT - JOURNAL ARTICLE DA - 891207 DP - 1988 Jan-Dec IS - 0033-4979 TA - Quad Sclavo Diagn PG - 115-9 SB - M CY - ITALY IP - 1-4 VI - 24 JC - QLU AA - Author EM - 9002 AB - The authors have investigated the level of circulating immune complexes (CIC) in 409 patients (some hospitalized) suffering from disease in which the presence of CIC had been suspected. The 10% (forty-one) was positive, and clinical manifestations related have shown, in the majority of patients, a close relation with diseases in which there was, or it was possible to presume, an immunological pathogenic mechanism. Besides the authors examine a case with close association between high level of CIC and leptospirosis. AD - Laboratorio di analisi chimico-cliniche e microbiologiche, Presidio ospedaliero, U.S.L.9, Prato Firienze. PMID- 3268904 CU - 92 TT - Risultati ed osservazioni sulla ricerca di immunocomplessi circolanti in soggetti con sospetta patologia autoimmune. EA - A SO - Quad Sclavo Diagn 1988 Jan-Dec;24(1-4):115-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 89299083 AU - Pereira MM AU - Andrade J TI - Epidemiological aspects of leptospirosis in a slum area in the city of Rio de Janeiro, Brazil. Search for leptospires and specific antibodies in rodents. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Brazil MH - Female MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology/transmission MH - Male MH - Muridae/*microbiology MH - Poverty Areas MH - Rats/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890810 DP - 1988 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 768-70 SB - M CY - ENGLAND IP - 5 VI - 82 JC - WBU AA - Author EM - 8910 AB - 101 Rattus norvegicus and 3 Mus musculus were captured in an urban slum of Rio de Janeiro city and examined for leptospiral infection. Direct examination of urine, serology (microagglutination) and culture together gave a positivity rate of 39%. Separately direct examination and serology gave positivity rates of 13% and 36% respectively. Serogroup Icterohaemorrhagiae predominated in the serological tests. Leptospires were isolated from 24 of the 104 rodents (23%), but 4 cultures died. The remaining 20 were identified as members of the Icterohaemorrhagiae serogroup, and 5 were further identified as serovar copenhageni. Human leptospiral infection, mainly caused by Icterohaemorrhagiae, is endemic in Rio de Janeiro city, and rodents are a major source of the disease. AD - Department of Bacteriology, Fundacao Oswasldo Cruz, Rio de Janeiro, Brazil. PMID- 3252599 CU - 91 SO - Trans R Soc Trop Med Hyg 1988;82(5):768-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 89258987 AU - Zhang SM AU - Cai Z AU - Ruan XZ TI - Cytological investigation of CSF in leptospiral cerebral arteritis. LA - Eng MH - Adult MH - Arteritis/*cerebrospinal fluid/pathology MH - Cerebral Artery Diseases/*cerebrospinal fluid/pathology MH - Child MH - Female MH - Human MH - Leptospirosis/*cerebrospinal fluid/pathology MH - Male PT - JOURNAL ARTICLE DA - 890627 DP - 1988 IS - 0257-716X TA - J Tongji Med Univ PG - 253-6 CY - CHINA IP - 4 VI - 8 JC - KAJ EM - 8909 PMID- 3249356 SO - J Tongji Med Univ 1988;8(4):253-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 89241394 AU - Kocik T TI - [Actual problems of leptospirosis in animals in Poland] LA - Pol MH - Animal MH - *Animals, Domestic MH - Cattle MH - Cattle Diseases/diagnosis/prevention & control MH - Dog Diseases/diagnosis/prevention & control MH - Dogs MH - Horse Diseases/diagnosis/prevention & control MH - Horses MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/diagnosis/prevention & control/*veterinary MH - Mass Screening/organization & administration/veterinary MH - Poland MH - Sheep MH - Sheep Diseases/diagnosis/prevention & control MH - Swine MH - Swine Diseases/diagnosis/prevention & control MH - Weil's Disease/diagnosis/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 890619 DP - 1988 IS - 0033-2100 TA - Przegl Epidemiol PG - 364-9 CY - POLAND IP - 4 VI - 42 JC - Q8T EM - 8908 PMID- 3247482 TT - Aktualne problemy leptospirozy u zwierzat w Polsce. SO - Przegl Epidemiol 1988;42(4):364-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 89162709 AU - Everard CO AU - Cawich F AU - Gamble PG AU - Everard JD TI - Prevalence of leptospirosis in Belize. LA - Eng MH - Animal MH - Belize MH - Cattle MH - Cattle Diseases/epidemiology MH - Dogs MH - Goats MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Sheep MH - Sheep Diseases/epidemiology MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 890411 DP - 1988 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 495-9 SB - M CY - ENGLAND IP - 3 VI - 82 JC - WBU AA - Author EM - 8906 AB - In a search for leptospirosis in Belize, at least one current case was diagnosed among 11 febrile hospital patients examined in a 2-week period in mid-1984. Sera from 440 survey subjects in 6 schools, 4 urban communities and 9 rural communities were examined for leptospiral antibodies by the microscopic agglutination test. 20 of 174 (11.5%) school pupils, 19 of 88 (22%) urban community subjects and 66/178 (37%) rural community subjects were positive at titres greater than or equal to 1:50, and 7.5%, 17% and 26%, respectively, were positive at greater than or equal to 1:100. Among all groups of survey subjects, serological reactions to antigens in the Australis serogroup predominated. Up to 81% of 155 sera from cattle in various areas of Belize were positive at titres greater than or equal to 1:100. Serological reactions to serogroup Sejroe predominated (43%), followed by Pyrogenes (16%) and Australis (15%). 20 of 71 (28%) pig sera were positive at greater than or equal to 1:100, predominantly to serovars in the Australis serogroup (51%). Of 162 sheep or goat sera examined, 65 (40%) were positive at greater than or equal to 1:100, mainly to serogroup Autumnalis (25%), followed by Australis (15%). AD - MRC/Barbados Government Leptospira Laboratory, Bridgetown. PMID- 3232193 SO - Trans R Soc Trop Med Hyg 1988;82(3):495-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 89161382 AU - Brethes B AU - Puech PL AU - Fraisse A AU - Dubois P AU - Domenech J AU - Bourdin P AU - Moreau JP AU - Capdevielle P AU - Dessouter D AU - Lambert M TI - [Leptospirosis and environment. Study of 2 major foci in New Caledonia] LA - Fre MH - Adult MH - Agricultural Workers' Diseases/*epidemiology MH - Animal MH - Animals, Domestic MH - Bacterial Vaccines/therapeutic use MH - English Abstract MH - Epidemiologic Methods MH - Female MH - Health Education MH - Human MH - Leptospira interrogans/immunology MH - Male MH - Middle Age MH - New Caledonia MH - Weil's Disease/*epidemiology/prevention & control/veterinary RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 890420 DP - 1988 IS - 0398-7620 TA - Rev Epidemiol Sante Publique PG - 436-42 SB - M CY - FRANCE IP - 6 VI - 36 JC - RST AA - Author EM - 8906 AB - A study of human and animal leptospirosis was carried out in new Caledonia's two most important focuses. This survey showed an annual incidence in the human population of 8.8 p. thousand in the Nera basin and 0.88 p. thousand in the Coulee basin. Male adults with agricultural and livestock occupations are the most exposed, especially from March to May, the end of the hot season. Frequent contacts with fresh water and animals, and the failure to use of gloves and boots, significantly increase the risk of contamination. Two factors of severity are important: serotype and age. Leptospira icterohaemorrhagiae is responsible for serious and fatal clinical forms and patients over 50 years of age have a maximum vital risk. In order to reduce the incidence and the severity of this disease, it appears desirable to vaccinate the farmers and the cattle breeders against L. icterohaemorrhagiae and to institute mass media information campaigns to warn against the risks of contamination. AD - Institut Pasteur de Noumea, Nouvelle-Caledonie. PMID- 3231845 CU - 91 TT - Leptospiroses et environment. Etude des deux foyers majeurs de Nouvelle- Caledonie. EA - A SO - Rev Epidemiol Sante Publique 1988;36(6):436-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 89147484 AU - Siddique IH AU - Mohamed AA TI - Cell-mediated immune response of goats to leptospirosis. LA - Eng MH - Animal MH - Cell Migration Inhibition MH - Goats/*immunology MH - Immunity, Cellular MH - Leptospirosis/immunology/*veterinary MH - Lymphocyte Transformation MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 890405 DP - 1988 IS - 0231-4622 TA - Acta Microbiol Hung PG - 283-7 SB - M CY - HUNGARY IP - 3 VI - 35 JC - 1AH AA - Author EM - 8906 AB - Cell-mediated immunity to Leptospira pomona was measured in goats by the leukocyte-migration inhibition test (LMIT) and microassay for stimulation of protein synthesis (SPS) with 3H-leucine. L. pomona soluble antigen was used in both tests. The migration indices in the group of goats infected with L. pomona were significantly lower (less than .001) as compared to control. The migration zones of the unstimulated peripheral blood leukocytes in the infected group were significantly smaller (less than .001) than those of the control. The SPS test was strongly positive in test animals and was negative in control. AD - Department of Microbiology, School of Veterinary Medicine, Tuskegee University, Alabama 36088. PMID- 3227798 SO - Acta Microbiol Hung 1988;35(3):283-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 89100457 AU - Bondarev LS TI - [Toxic shock] LA - Rus MH - Adolescence MH - Adult MH - Aged MH - Child MH - Enterobacteriaceae Infections/complications MH - Human MH - Leptospirosis/complications MH - Meningitis/complications MH - Middle Age MH - Pneumonia, Lobar MH - Shock, Septic/*etiology/therapy PT - JOURNAL ARTICLE DA - 890222 DP - 1988 IS - 0038-5077 TA - Sov Med PG - 100-2 CY - USSR IP - 5 JC - UW7 EM - 8904 PMID- 3212519 TT - Toksikoiniektsionnyi shok. SO - Sov Med 1988;(5):100-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 89075935 AU - Andreescu N TI - Leptospirosis cases in man determined by the Patoc 1 saprophytic strain. LA - Eng MH - Antibodies, Bacterial/*analysis MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Serodiagnosis/methods RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890126 DP - 1988 Jan-Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 23-7 CY - ROMANIA IP - 1 VI - 47 JC - 8EM EM - 8903 PMID- 3202686 CU - 91 SO - Arch Roum Pathol Exp Microbiol 1988 Jan-Mar;47(1):23-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 89070335 AU - Hata K AU - Ono E AU - Yanagawa R TI - Comparative studies of strains Ictero No. I and RGA as the type strain of Leptospira interrogans: agglutinin absorption test, protein and antigen profiles, and enzyme activities. LA - Eng MH - Agglutination Tests MH - Antigens, Bacterial/isolation & purification MH - Bacterial Proteins/isolation & purification MH - Comparative Study MH - Cross Reactions MH - Enzymes/isolation & purification MH - Leptospira interrogans/analysis/*classification/immunology MH - Species Specificity RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) RN - 0 (Enzymes) PT - JOURNAL ARTICLE DA - 890123 DP - 1988 IS - 0385-5600 TA - Microbiol Immunol PG - 817-32 SB - M CY - JAPAN IP - 8 VI - 32 JC - MX7 AA - Author EM - 8903 AB - Strain Ictero No. I, the first isolate of Leptospira, isolated by Inada and Ido in 1914, was found to be sufficiently qualified to be the type strain of Leptospira interrogans rather than strain RGA. In an agglutinin absorption test, anti-Ictero No. I serum was not absorbed completely with strain RGA, and 25% of the homologous titer remained unabsorbed, while anti-RGA serum was completely absorbed with strain Ictero No. I. Thus, strain Ictero No. I was not serologically identical with strain RGA, and the two strains were considered to be different serovars. A protein band with a molecular weight of approximately 33,000 daltons was detected in strain Ictero No. I but not in strain RGA by SDS-PAGE. By Western blotting, this protein band was detectable with anti-Ictero No. I serum but not with anti-RGA serum. The presence of the 33K protein in strain Ictero No. I, but not in strain RGA, was confirmed by radioimmunoprecipitation using [125I]-labeled antigens, indicating that the protein antigen was surface-exposed. Only 8 of the 89 enzymes activities were different between strains Ictero No. I and RGA (line Sapporo). From the above results, we propose that strain Ictero No. I should be designated as the type strain of L. interrogans instead of strain RGA. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University. PMID- 3200169 CU - 91 SO - Microbiol Immunol 1988;32(8):817-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 89058387 AU - Andreescu N AU - Tacorian D AU - Duminica E AU - Filip M AU - Sosin A TI - [Serological study of the ocular complications of human leptospirosis] LA - Rum MH - Antibiotics/therapeutic use MH - Antibodies, Bacterial/analysis MH - Comparative Study MH - English Abstract MH - Eye Diseases/*diagnosis/drug therapy/etiology MH - Human MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospirosis/*complications/diagnosis/drug therapy MH - Serodiagnosis/methods MH - Weil's Disease/*complications/diagnosis/drug therapy RN - 0 (Antibiotics) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 890111 DP - 1988 Jan-Mar IS - 0376-4494 TA - Rev Ig [Bacteriol] PG - 41-6 CY - ROMANIA IP - 1 VI - 33 JC - S7C EM - 8903 PMID- 3194619 CU - 91 TT - Investigarea serologica in complicatiile oculare ale leptospirozelor la om. EA - A SO - Rev Ig [Bacteriol] 1988 Jan-Mar;33(1):41-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 89046346 AU - Bigaignon G AU - Colin JF AU - Mulumba M AU - Damoiseaux P AU - Gohy P AU - Lens E AU - Passelecq E AU - Rosoux A AU - Reynaert M AU - Piot P TI - [Icterohemorrhagic leptospirosis: apropos of 5 case reports] LA - Fre MH - Adolescence MH - Adult MH - Disease Reservoirs MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Leptospira/classification MH - Male MH - Middle Age MH - Serotyping MH - *Weil's Disease/complications/diagnosis/transmission PT - JOURNAL ARTICLE DA - 881202 DP - 1988 IS - 0001-5512 TA - Acta Clin Belg PG - 273-81 CY - BELGIUM IP - 4 VI - 43 JC - 0KW EM - 8902 PMID- 3188801 TT - La leptospirose icteero--hemorragique: a propos de 5 observations. EA - A SO - Acta Clin Belg 1988;43(4):273-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 89014004 AU - Fukunaga M AU - Mifuchi I TI - Mechanism of streptomycin resistance in Leptospira biflexa strain Urawa. LA - Eng MH - Bacterial Proteins/biosynthesis MH - Drug Resistance, Microbial/*genetics MH - Leptospira/*drug effects/genetics/metabolism MH - Mutation MH - Ribosomes/drug effects/metabolism MH - Streptomycin/*pharmacology RN - 0 (Bacterial Proteins) RN - 57-92-1 (Streptomycin) PT - JOURNAL ARTICLE DA - 881123 DP - 1988 IS - 0385-5600 TA - Microbiol Immunol PG - 641-4 SB - M CY - JAPAN IP - 6 VI - 32 JC - MX7 AA - Author EM - 8901 AB - The mechanism of streptomycin resistance of Leptospira biflexa was investigated. A streptomycin-resistance mutant of Leptospira showed cross-resistance to dihydrostreptomycin but not to other antibiotics. Enzymatic inactivation of the drug could not be demonstrated in this mutant. Protein synthesis on the ribosomes from the mutant was insensitive to streptomycin. These results suggest that ribosomal resistance is the reason for streptomycin resistance in Leptospira biflexa. AD - Faculty of Pharmacy and Pharmaceutical Science, University of Fukuyama, Hiroshima. PMID- 3173149 CU - 91 SO - Microbiol Immunol 1988;32(6):641-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 89181226 AU - Yamaguchi T AU - Ono E AU - Yanagawa R TI - Expression of antigen genes of Leptospira interrogans serovar canicola in Escherichia coli. LA - Eng MH - Antigens, Bacterial/*genetics/isolation & purification MH - Blotting, Western MH - Cloning, Molecular MH - DNA, Bacterial/genetics MH - Escherichia coli/genetics MH - Gene Expression Regulation MH - *Genes, Bacterial MH - Leptospira interrogans/genetics/*immunology MH - Plasmids MH - Recombination, Genetic MH - Support, Non-U.S. Gov't MH - Transformation, Genetic RN - 0 (Antigens, Bacterial) RN - 0 (DNA, Bacterial) RN - 0 (Plasmids) PT - JOURNAL ARTICLE DA - 890511 DP - 1988 IS - 0385-5600 TA - Microbiol Immunol PG - 1179-87 SB - M CY - JAPAN IP - 12 VI - 32 JC - MX7 AA - Author EM - 8907 AB - Leptospira interrogans serovar canicola DNA was cloned into the plasmid pBR322 and introduced into E. coli. Eight out of approximately 10,000 transformants were found to express antigens of canicola by ELISA including colony ELISA blot test using anti-canicola antiserum. The canicola antigens expressed in the transformants reacted with the antisera against the serovars belonging to Canicola serogroup and other serogroups of L. interrogans. They did not react, however, with the antiserum against L. biflexa (with only one exception) nor with the antiserum against Leptonema illini. Thus, the recombinant DNA technique may provide alternative possibilities for preparing antigens of leptospires. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University. PMID- 3070308 CU - 92 SO - Microbiol Immunol 1988;32(12):1179-87 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 89045621 AU - Bahaman AR AU - Ibrahim AL TI - A review of leptospirosis in Malaysia. LA - Eng MH - Animal MH - Animals, Domestic/*microbiology MH - Animals, Wild/*microbiology MH - Human MH - Leptospira/classification/isolation & purification MH - Leptospirosis/*epidemiology/veterinary MH - Malaysia MH - Soil Microbiology MH - Water Microbiology PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 881216 DP - 1988 IS - 0165-7380 TA - Vet Res Commun PG - 179-89 SB - M CY - ENGLAND IP - 2-3 VI - 12 JC - XCD AA - Author EM - 8902 AB - This paper reviews the literature on leptospirosis in Malaysia from its first description in 1928 until the present day. Most of the early reports were on investigations of leptospirosis in wildlife and man and up-to-date, thirty-seven leptospiral serovars from thirteen serogroups have been bacteriologically identified. The thirteen serogroups are: Australis, Autumnalis Bataviae, Canicola, Celledoni, Grippotyphosa, Hebdomadis, Icterohaemorrhagiae, Javanica, Pomona, Pyrogenes, Sejroe and Tarassovi. Rats have been ascribed as the principal maintenance host of leptospires in Malaysia. However, serovars from the Pomona, Pyrogenes and Sejroe serogroups have yet to be isolated from rats. It is considered that the majority of leptospirosis cases in man were due to association of man with an environment where rats were plentiful. Recent investigations on domestic animals disclosed a high prevalence of infection in cattle and pigs and they were suspected as being the maintenance host for serovar hardjo and pomona respectively. There is ample scope for research in leptospirosis, particularly in the epidemiology and control of the disease in domestic animals. The strategy to control the infection in domestic animals and man in Malaysia is bound to be different from that of the temperate countries, basically due to the presence of a large number of leptospiral serovars in wildlife, further confounded by geographical and financial constraints. AD - Faculty of Veterinary Medicine and Animal Science, University Pertanian Malaysia, Serdang, Selangor. RF - 42 PMID- 3055663 CU - 90 SO - Vet Res Commun 1988;12(2-3):179-89 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 92166646 AU - Ewes AM AU - Kasem AS AU - Elmolla A TI - Bovine leptospirosis: bacteriologic versus serologic diagnosis of cows at slaughter. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/immunology/*microbiology MH - Enzyme-Linked Immunosorbent Assay/veterinary MH - Leptospira/immunology MH - Leptospirosis/immunology/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 920402 DP - 1988 IS - 0013-2446 TA - J Egypt Public Health Assoc PG - 301-9 CY - EGYPT IP - 5-6 VI - 63 JC - I07 EM - 9206 PMID- 2979948 NP - X SO - J Egypt Public Health Assoc 1988;63(5-6):301-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 89158916 AU - Yamaguchi T AU - Ono E AU - Ito T AU - Yanagawa R TI - Restriction endonuclease DNA analysis of antigenic variants of leptospires selected by monoclonal antibodies. LA - Eng MH - Antibodies, Monoclonal/diagnostic use MH - Antigenic Variation MH - Comparative Study MH - DNA Restriction Enzymes/*analysis MH - Genetic Markers/*analysis MH - Leptospira interrogans/*classification/enzymology/genetics/isolation & purification RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (Antibodies, Monoclonal) RN - 0 (Genetic Markers) PT - JOURNAL ARTICLE DA - 890418 DP - 1988 IS - 0385-5600 TA - Microbiol Immunol PG - 1007-11 SB - M CY - JAPAN IP - 10 VI - 32 JC - MX7 AA - Author EM - 8906 AB - The genome of antigenic variant CV (CT3)-1 derived from Leptospira interrogans serovar canicola was compared by cleavage with restriction endonucleases with the parent and serovar bafani, to which the variant was serologically most closely related. No differences were observed between the parent and variant in DNA restriction endonuclease patterns using eight restriction endonucleases. Serovar bafani was different in the patterns from the parent and antigenic variant CV (CT3)-1. The two antigenic variants derived from serovar hebdomadis, HV (H16)-1 and HV (H19)-1 which belonged serologically to serovars jules and hebdomadis, respectively, were compared by restriction endonuclease DNA analysis with the parent and serovar jules. No differences were observed between the parent and variants in DNA restriction endonuclease patterns using the same enzymes. But some differences were observed in DNA restriction endonuclease patterns between HV (H16)-1 and serovar jules. Thus, the antigenic variant selected from the parent by the anti-parent monoclonal antibody and serologically different from the parent, being identified either as a new serovar or as a known one, was found to be similar to the parent by the restriction endonuclease DNA analysis. AD - Department of Hygiene, Faculty of Veterinary Medicine, Hokkaido University. PMID- 2852766 CU - 93 SO - Microbiol Immunol 1988;32(10):1007-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 89096552 AU - Tamai T AU - Sada E AU - Kobayashi Y TI - Restriction endonuclease DNA analysis of Leptospira interrogans serovars Icterohaemorrhagiae and Copenhageni. LA - Eng MH - DNA Restriction Enzymes MH - DNA, Bacterial/*analysis MH - Leptospira interrogans/analysis/*classification/genetics MH - Serotyping RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 890223 DP - 1988 IS - 0385-5600 TA - Microbiol Immunol PG - 887-94 SB - M CY - JAPAN IP - 9 VI - 32 JC - MX7 AA - Author EM - 8904 AB - Leptospira interrogans serovar icterohaemorrhagiae strains Ictero No. I and RGA and serovar copenhageni strains M20, Shiromizu and Shibaura were examined by restriction endonuclease DNA analysis. Fifteen endonucleases (AluI, BamHI, BglII, EcoRI, HaeIII, HhaI, HindIII, KpnI, PstI, SacI, SalI, SmaI, StyI, XbaI and XhoI) were used as the digesting enzymes. Strain Ictero No. I showed endonuclease cleavage patterns which differed from those of the other four strains only when it was digested with enzymes KpnI and HindIII. When digested with KpnI, an extra band of about 5.4 kb was clearly produced, and when digested with HindIII, an extra band of about 25 kb was produced. When the other 13 enzymes were used, no differences were found between the endonuclease cleavage patterns among the five strains. Moreover, strains RGA, M20, Shiromizu and Shibaura could not be distinguished by the restriction endonuclease DNA analysis using all 15 endonucleases. In addition, six newly isolated leptospires from patients with leptospirosis and from Rattus norvegicus were compared with the Ictero No. I and M20 strains, by restriction endonuclease DNA analysis using enzymes KpnI and HindIII. Three leptospires belonging to serovar icterohaemorrhagiae showed the same endonuclease cleavage patterns as the M20 strain. The other three strains, which belong to serovar copenhageni, showed almost the same endonuclease cleavage patterns as the M20 strain; only the Kai ima 702 strain produced an extra band which was not identical to the Ictero No. I-specific extra band when digested with HindIII. The leptospiral restriction endonuclease DNA analysis has revealed taxonomic structures that are unrecognized by serology alone. AD - First Department of Internal Medicine, Faculty of Medicine, Ehime University. PMID- 2850447 CU - 93 SO - Microbiol Immunol 1988;32(9):887-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 89095696 AU - Avdeeva MG AU - Lebedev VV AU - Shubich MG TI - [Cytochemical studies of leukocytes in patients with leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Alkaline Phosphatase/blood MH - Blood Bactericidal Activity MH - Carboxylic Ester Hydrolases/blood MH - English Abstract MH - Human MH - Male MH - Middle Age MH - Neutrophils/*physiology MH - Weil's Disease/*blood RN - EC 3.1.1 (Carboxylic Ester Hydrolases) RN - EC 3.1.1.1 (carboxylesterase) RN - EC 3.1.3.1 (Alkaline Phosphatase) PT - JOURNAL ARTICLE DA - 890221 DP - 1988 IS - 0023-6748 TA - Lab Delo PG - 22-4 CY - USSR IP - 11 JC - KYU EM - 8904 PMID- 2463411 CU - 95 TT - Tsitokhimicheskie issledovaniia leikotsitov bol'nykh leptospirozom. EA - A SO - Lab Delo 1988;(11):22-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 89070331 AU - Takimoto T AU - Ono E AU - Ito T AU - Yanagawa R TI - Affinity constants of anti-leptospira monoclonal antibodies, numbers of antigenic determinants on leptospiras, and their influence on the microscopic agglutination test and ELISA. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/immunology MH - *Antibodies, Monoclonal MH - Antibody Affinity MH - Antigens, Bacterial/*immunology MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Epitopes/analysis MH - Leptospira/*immunology MH - Leptospira canicola/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 890123 DP - 1988 IS - 0385-5600 TA - Microbiol Immunol PG - 775-84 SB - M CY - JAPAN IP - 8 VI - 32 JC - MX7 AA - Author EM - 8903 AB - The affinity constants of anti-canicola and anti-hebdomadis monoclonal antibodies and the numbers of antigenic determinants per organism of each serovar of leptospira were determined, and their influence on the results of microscopic agglutination test (MAT) and ELISA were examined. In the combinations of a monoclonal antibody and some serovar which showed higher affinity constants at levels of 10(7) to 10(8)/M order, both MAT and ELISA were positive except for one combination, while in the combinations which gave lower affinity constants at levels of 10(6)/M order, MAT was positive but ELISA was negative. The number of antigenic determinants seemed to have no significant influence on the results. The disagreement due to the difference in the threshold affinities of MAT and ELISA should be considered in the use of monoclonal antibodies in the taxonomy of leptospira. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University. PMID- 2462157 CU - 95 SO - Microbiol Immunol 1988;32(8):775-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 88086346 AU - Sillerud CL AU - Bey RF AU - Ball M AU - Bistner SI TI - Serologic correlation of suspected Leptospira interrogans serovar pomona-induced uveitis in a group of horses. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Horse Diseases/*etiology/immunology MH - Horses MH - Leptospira interrogans/immunology MH - Uveitis/etiology/*veterinary MH - Weil's Disease/complications/immunology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880212 DP - 1987 Dec 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1576-8 SB - M CY - UNITED STATES IP - 12 VI - 191 JC - HAV AA - Author EM - 8804 AB - After the observation of 2 horses with uveitis on a horse farm in the Minnesota River valley, 100 horses from this geographic area were given ophthalmologic examinations and were evaluated serologically for leptospirosis. A statistically significant (P less than 0.001) association was observed between the finding of antibodies against Leptospira interrogans serovar pomona and uveitis. AD - Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul 55108. PMID- 3693011 CU - 91 SO - J Am Vet Med Assoc 1987 Dec 15;191(12):1576-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 88212366 AU - Cheng SQ AU - Wang CX AU - Ye DN AU - Dai BM TI - [Comparison of protein profiles and McAb-recognized antigens of pathogenic and nonpathogenic leptospires] LA - Chi MH - Antibodies, Monoclonal/immunology MH - Antigens, Bacterial/*immunology MH - Bacterial Proteins/*analysis MH - Comparative Study MH - Electrophoresis MH - English Abstract MH - Leptospira/*immunology/pathogenicity MH - Leptospira interrogans/*immunology MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE DA - 880616 DP - 1987 Dec IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 310-3 CY - CHINA IP - 4 VI - 18 JC - GEB EM - 8808 PMID- 3449418 CU - 91 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1987 Dec;18(4):310-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 88180125 AU - Semenovich VN AU - Polotskii IuE AU - Daiter AB TI - [Interaction of Leptospira with the host's body in the infectious process in guinea pigs] LA - Rus MH - Animal MH - Antibodies, Bacterial/analysis MH - Comparative Study MH - English Abstract MH - Epithelium/microbiology/pathology MH - Guinea Pigs MH - Kidney/microbiology/pathology MH - Leptospira interrogans/immunology/*pathogenicity MH - Liver/microbiology/pathology MH - Time Factors MH - Virulence MH - Weil's Disease/immunology/*microbiology/pathology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880422 DP - 1987 Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 81-7 SB - M CY - USSR IP - 12 JC - Y9O AA - Author EM - 8807 AB - In experiments on guinea pigs the pathogenicity of leptospires is manifested by their adhesion to liver cells, colonization of the surface of these cells, accumulation of leptospires in the renal interstice and their colonization of the nephrothelial surface of proximal convoluted tubules in the kidneys, by toxic microcirculatory disturbances, dystrophy and necrosis of nephrothelial cells. Then the primary toxic action of circulating leptospires, microcirculatory disturbances and hemorrhagic syndrome augment during the colonization of the surface of liver cells, accompanied by their dystrophy and dissociation, as well as by jaundice. The accumulation of leptospires in the renal interstice and their subsequent multiplication on the nephrothelium of the proximal convoluted tubules are responsible for the development of interstitial nephritis and necrotic nephrosis. The persistence of lesions in the liver and kidneys, occurring in some cases in spite of elimination of the infective agent from these organs due to increasing antibody production suggests the toxic action of immune complexes. PMID- 3445736 CU - 91 TT - Vzaimodeistvie leptospir s organizmom khoziaina pri infektsionnom protsesse u morskikh svinok. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1987 Dec;(12):81-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 88133795 AU - Arda M AU - Bisping W AU - Aydin N AU - Istanbulluoglu E AU - Akay O AU - Izgur M AU - Karaer Z AU - Diker S AU - Kirpal G TI - [Etiologic studies of abortion in sheep with special reference to detection of Brucella, Campylobacter, Salmonella, Listeria, Leptospira and Chlamydia] LA - Ger MH - Abortion, Veterinary/*etiology MH - Animal MH - Brucella/isolation & purification MH - Campylobacter fetus/isolation & purification MH - Chlamydia psittaci/isolation & purification MH - English Abstract MH - Female MH - Leptospira/isolation & purification MH - Listeria/isolation & purification MH - Pregnancy MH - Salmonella/isolation & purification MH - Sheep MH - Sheep Diseases/*etiology MH - Toxoplasma/isolation & purification PT - JOURNAL ARTICLE DA - 880308 DP - 1987 Dec 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 405-8 CY - GERMANY, WEST IP - 12 VI - 100 JC - 9Q8 EM - 8805 PMID- 3435407 TT - Atiologische Untersuchungen uber den Abort bei Schafen unter besonderer Berucksichtigung des Nachweises von Brucellen, Campylobacter, Salmonellen, Listerien, Leptospiren und Chlamydien. EA - A SO - Berl Munch Tierarztl Wochenschr 1987 Dec 1;100(12):405-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 88185792 AU - De Biase L AU - De Curtis G AU - Paparoni S AU - Sciarra D AU - Campa PP TI - Fatal leptospiral myocarditis. LA - Eng MH - Case Report MH - Heart Failure, Congestive/*etiology/pathology MH - Human MH - Male MH - Middle Age MH - Myocardium/pathology MH - Weil's Disease/*complications/pathology PT - JOURNAL ARTICLE DA - 880524 DP - 1987 Nov IS - 0046-5968 TA - G Ital Cardiol PG - 992-4 SB - M CY - ITALY IP - 11 VI - 17 JC - FBE AA - Author EM - 8807 AB - Clinical, instrumental and post-mortem studies were carried out in a patient with intractable cardiac failure, whose death was attribute to Weil's syndrome. A post-mortem examination showed the presence of numerous petechiae on the heart layers and diffuse lymphomonocytic infiltrates in the myocardium, epicardium and endocardium. We suggest that in patients affected by leptospirosis--an endemic disease with a possible fatal outcome--it is necessary to determine carefully any involvement of the cardiovascular system which may play a determinant role in the evolution of the disease. AD - Cattedra di Angiologia, Universita di Roma, La Sapienza. PMID- 3446572 SO - G Ital Cardiol 1987 Nov;17(11):992-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 88100998 AU - Feresu SB TI - Serological survey of leptospiral antibodies in cattle in Zimbabwe. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*epidemiology MH - Cross Reactions MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Support, Non-U.S. Gov't MH - Zimbabwe RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880202 DP - 1987 Nov IS - 0049-4747 TA - Trop Anim Health Prod PG - 209-14 SB - M CY - SCOTLAND IP - 4 VI - 19 JC - WG2 AA - Author EM - 8804 AB - A total of 2,382 sera from 92 herds widely distributed throughout Zimbabwe were screened using the Microscopic Agglutination Test against representatives of 18 serogroups of Leptospira interrogans and one representative of Leptospira biflexa. The prevalence of leptospiral titres at a serum dilution of 1:100 was 27%, the most common titres being to antigens from the Sejroe and Tarassovi serogroups. Significantly different proportions of titres were shown among the three farming systems and among the eight provinces of Zimbabwe. AD - Department of Biological Sciences, University of Zimbabwe, Harare. PMID- 3424449 CU - 91 SO - Trop Anim Health Prod 1987 Nov;19(4):209-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 88087845 AU - LeFebvre RB TI - DNA probe for detection of the Leptospira interrogans serovar hardjo genotype hardjo-bovis. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - DNA Restriction Enzymes MH - DNA, Bacterial/*genetics MH - Genes, Bacterial MH - Genotype MH - Leptospira interrogans/classification/*genetics/isolation & purification MH - Nucleic Acid Hybridization MH - Weil's Disease/microbiology/*veterinary RN - EC 3.1.21 (DNA Restriction Enzymes) RN - EC 3.1.21.- (Deoxyribonuclease EcoRI) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 880212 DP - 1987 Nov IS - 0095-1137 TA - J Clin Microbiol PG - 2236-8 SB - M CY - UNITED STATES IP - 11 VI - 25 JC - HSH AA - Author EM - 8804 AB - A DNA probe is described for the diagnostic and taxonomic identification of the North American cattle pathogen Leptospira interrogans genotype hardjo-bovis. The probe is specific for this genotype and does not hybridize to genomic DNA of any other leptospire pathogen commonly found in North America. AD - National Animal Disease Center, Ames, Iowa 50010. PMID- 2826538 CU - 93 SO - J Clin Microbiol 1987 Nov;25(11):2236-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 88087809 AU - LeFebvre RB AU - Thiermann AB AU - Foley J TI - Genetic and antigenic differences of serologically indistinguishable leptospires of serovar hardjo. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial/*analysis MH - Autoradiography MH - Cattle MH - Cytosine/analysis MH - DNA, Bacterial/*analysis MH - Epitopes/analysis MH - Guanine/analysis MH - Immunoassay MH - Leptospira interrogans/*classification/genetics/immunology RN - 0 (Antigens, Bacterial) RN - 0 (DNA, Bacterial) RN - 0 (Epitopes) RN - 71-30-7 (Cytosine) RN - 73-40-5 (Guanine) PT - JOURNAL ARTICLE DA - 880212 DP - 1987 Nov IS - 0095-1137 TA - J Clin Microbiol PG - 2094-7 SB - M CY - UNITED STATES IP - 11 VI - 25 JC - HSH AA - Author EM - 8804 AB - Pathogenic leptospires of serovar hardjo isolated from North American cattle were compared genetically and antigenically to reference strain hardjoprajitno of the Sejroe serogroup. Guanine-plus-cytosine (G+C) contents were determined for the genomes, and microscopic agglutination, Western blotting (immunoblotting), and immunoprecipitation were used to characterize antigenic relatedness. Major differences were demonstrated between the isolates and the reference strain. The G+C content of the reference strain was calculated to be approximately 34 +/- 1%, and those of the isolates were calculated at 39 +/- 1%. Antigenic differences between the isolates and the reference strain were identified by using rabbit immune serum raised against a hardjo isolate exhaustively adsorbed with hardjoprajitno whole and sonicated cells. Western blot analysis and immunoprecipitation using this adsorbed serum revealed antigens apparently unique for the hardjo isolates. Microscopic agglutination with the adsorbed rabbit serum did not agglutinate hardjoprajitno when diluted 1:2 but agglutinated bovine isolates to a 1:32 dilution. Bovine antiserum raised against the isolates was also used to identify antigens by immunoprecipitation. AD - National Animal Disease Center, U.S. Department of Agriculture, Ames, Iowa 50010. PMID- 2447118 CU - 95 SO - J Clin Microbiol 1987 Nov;25(11):2094-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 88072004 AU - Clayton SN TI - Leptospira hardjo vaccination regime [letter] LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - Female MH - Human MH - Leptospirosis/*prevention & control/veterinary MH - Occupational Diseases/*prevention & control MH - Vaccination/*veterinary PT - LETTER DA - 880119 DP - 1987 Oct 10 IS - 0042-4900 TA - Vet Rec PG - 358-9 SB - M CY - ENGLAND IP - 15 VI - 121 JC - XBS EM - 8803 PMID- 3686796 CU - 91 SO - Vet Rec 1987 Oct 10;121(15):358-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [60 medline neighbors] UI - 88063745 AU - Ito T AU - Yanagawa R TI - Leptospiral attachment to four structural components of extracellular matrix. LA - Eng MH - Animal MH - Attachment Sites (Microbiology) MH - *Bacterial Adhesion MH - Collagen MH - Extracellular Matrix/*microbiology MH - Fibronectins MH - Guinea Pigs MH - Hamsters MH - Hyaluronic Acid MH - In Vitro MH - Laminin MH - Leptospira interrogans/*physiology MH - Virulence RN - 0 (Fibronectins) RN - 0 (Laminin) RN - 9004-61-9 (Hyaluronic Acid) RN - 9007-34-5 (Collagen) PT - JOURNAL ARTICLE DA - 880113 DP - 1987 Oct IS - 0021-5295 TA - Nippon Juigaku Zasshi PG - 875-82 CY - JAPAN IP - 5 VI - 49 JC - KRJ EM - 8803 PMID- 3682525 CU - 92 SO - Nippon Juigaku Zasshi 1987 Oct;49(5):875-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 88055414 AU - Seki M AU - Sato T AU - Arimitsu Y AU - Matuhasi T AU - Kobayashi S TI - One-point method for serological diagnosis of leptospirosis: a microcapsule agglutination test. LA - Eng MH - *Agglutination Tests MH - Comparative Study MH - Human MH - Leptospirosis/*diagnosis MH - Predictive Value of Tests MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 871230 DP - 1987 Oct IS - 0950-2688 TA - Epidemiol Infect PG - 399-405 SB - M CY - ENGLAND IP - 2 VI - 99 JC - EPI AA - Author EM - 8803 AB - This paper describes a simple and rapid microcapsule agglutination (MCA) test. The results obtained by this new test have been compared with those obtained by the microtitre MCA and the microscopic agglutination (MA) test. The procedures required for the new test are easier and can be performed more rapidly than those necessary for the microtitre MCA test. Furthermore, the new test is more sensitive than the MA test in the early stages of leptospirosis. This new test appears satisfactory as a screening test for the early diagnosis of leptospirosis. AD - Department of Research, Japan Lyophilization Laboratories, Tokyo. PMID- 3678401 SO - Epidemiol Infect 1987 Oct;99(2):399-405 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 88055413 AU - Arimitsu Y AU - Matuhasi T AU - Kobayashi S AU - Sato T AU - Cui JJ TI - Serodiagnosis of leptospirosis in China by the one-point MCA method. LA - Eng MH - Agglutination Tests MH - China MH - Chromatography, Gel MH - Human MH - Leptospirosis/*diagnosis MH - Predictive Value of Tests MH - Reagent Kits, Diagnostic MH - Weil's Disease/*diagnosis RN - 0 (Reagent Kits, Diagnostic) PT - JOURNAL ARTICLE DA - 871230 DP - 1987 Oct IS - 0950-2688 TA - Epidemiol Infect PG - 393-8 SB - M CY - ENGLAND IP - 2 VI - 99 JC - EPI AA - Author EM - 8803 AB - The one-point MCA method is very simple to perform and useful as a screening test in diagnosing leptospirosis in routine clinical laboratories. The kit, sensitized with six serovars occurring in Japan, was also useful in detecting serum antibodies of patients with leptospirosis in China. AD - Department of Applied Immunology, National Institute of Health, Tokyo, Japan. PMID- 3678400 CU - 91 SO - Epidemiol Infect 1987 Oct;99(2):393-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 88055412 AU - Bahaman AR AU - Ibrahim AL AU - Adam H TI - Serological prevalence of leptospiral infection in domestic animals in West Malaysia. LA - Eng MH - Agglutination Tests MH - Animal MH - *Animals, Domestic MH - Antibodies, Bacterial/analysis MH - Buffaloes MH - Cattle MH - Cattle Diseases/epidemiology MH - Goats MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/*veterinary MH - Malaysia MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 871230 DP - 1987 Oct IS - 0950-2688 TA - Epidemiol Infect PG - 379-92 SB - M CY - ENGLAND IP - 2 VI - 99 JC - EPI AA - Author EM - 8803 AB - A cross-sectional serological survey of domestic animals in West Malaysia revealed that 25.5% of the animals examined had agglutinating antibodies to one or more antigens belonging to Leptospira interrogans. Significant prevalence of infection was observed in cattle (40.5%), buffaloes (31%) and pigs (16%). The Sejroe serogroup was shown to be the principal one involved in cattle and buffaloes, and to a lesser extent the Tarassovi and Pomona serogroups. Evidence of infection in domestic animals by strains bearing the other seven antigens appeared insignificant and was indicative of sporadic infection. A majority of the large (semi-intensive) cattle and buffalo farms demonstrated a high prevalence of leptospiral infection. In both species of domestic animals mentioned above, the prevalence of infection was significantly higher (P = 0.01) in the semi-intensive farms than in the smallholdings. Amongst cattle, the droughtmasters had the highest prevalence whilst the Kedah-Kelantan (an indigenous breed) had the lowest prevalence of leptospiral infection. In general, the temperate breeds of cattle had a significantly (P = 0.01) higher prevalence of infection than local breeds. Leptospiral infection in goats and sheep was shown to be sporadic, and the Pomona serogroup was the principal leptospiral serogroup involved in these small ruminants. The prevalence of infection in pigs was observed to decline during the study period, and it is suspected that pigs in West Malaysia are the maintenance host for serovar pomona whilst cattle are the maintenance host for serovar hardjo. Overall, it appears that domestic animals in Malaysia will play a bigger role in the epidemiology of leptospiral infection with the advent of sophisticated farming. AD - Faculty of Veterinary Medicine and Animal Science, Universiti Pertanian Malaysia, Serdang, Selangor. PMID- 3678399 CU - 91 SO - Epidemiol Infect 1987 Oct;99(2):379-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 88055411 AU - Coghlan JD AU - Kmety E TI - A new serovar mogdeni of serogroup Tarassovi of Leptospira interrogans isolated from a sewage plant in England. LA - Eng MH - Agglutination Tests MH - Animal MH - England MH - Human MH - Leptospira interrogans/*classification/isolation & purification MH - Serotyping MH - *Sewage PT - JOURNAL ARTICLE DA - 871230 DP - 1987 Oct IS - 0950-2688 TA - Epidemiol Infect PG - 373-7 SB - M CY - ENGLAND IP - 2 VI - 99 JC - EPI AA - Author EM - 8803 AB - Among 30 strains of leptospires isolated from samples of sewage taken before and during treatment at two sewage plants in England, only one appeared to belong to Leptospira interrogans, the species that comprises the leptospires that are pathogenic to man and animals. That strain, Compton 746, was isolated from settled sewage, before treatment at a treatment plant that deals mainly with human sewage. It was shown serologically to belong to serogroup Tarassovi and appears to represent a new serovar that has been named mogdeni after the name of the sewage plant, Mogden, from which it was isolated. AD - Public Health Laboratory Service, Colindale, London, UK. PMID- 3678398 SO - Epidemiol Infect 1987 Oct;99(2):373-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 87309929 AU - Solbrig MV AU - Sher JH AU - Kula RW TI - Rhabdomyolysis in leptospirosis (Weil's disease). LA - Eng MH - Case Report MH - Female MH - Human MH - Middle Age MH - Muscles/*pathology MH - Rhabdomyolysis/*pathology MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 871019 DP - 1987 Oct IS - 0022-1899 TA - J Infect Dis PG - 692-3 SB - A SB - M CY - UNITED STATES IP - 4 VI - 156 JC - IH3 EM - 8712 PMID- 3624913 SO - J Infect Dis 1987 Oct;156(4):692-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 88223546 AU - Wang GX TI - [Clinical differentiation between the pulmonary hemorrhagic type of leptospirosis and Staphylococal aureus pneumonia] LA - Chi MH - Comparative Study MH - Diagnosis, Differential MH - English Abstract MH - Hemoptysis/etiology MH - Human MH - Leptospirosis/complications/*diagnosis MH - Lung Diseases/*diagnosis MH - Pneumonia, Staphylococcal/complications/*diagnosis MH - Staphylococcus aureus PT - JOURNAL ARTICLE DA - 880705 DP - 1987 Oct IS - 0253-2689 TA - Chung Hua Chieh Ho Ho Hu Hsi Tsa Chih PG - 278-80, 308-9 CY - CHINA IP - 5 VI - 10 JC - CYH EM - 8809 PMID- 3450416 EA - A SO - Chung Hua Chieh Ho Ho Hu Hsi Tsa Chih 1987 Oct;10(5):278-80, 308-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 88182032 AU - Chan OY AU - Chia SE AU - Nadarajah N AU - Sng EH TI - Leptospirosis risk in public cleansing and sewer workers. LA - Eng MH - Antibodies, Bacterial/analysis MH - Human MH - Hydrogen-Ion Concentration MH - Leptospira/immunology MH - Leptospirosis/*epidemiology/etiology MH - Male MH - Occupational Diseases/*epidemiology/etiology MH - Risk Factors MH - *Sanitation MH - Sewage MH - Singapore MH - Water RN - 0 (Antibodies, Bacterial) RN - 7732-18-5 (Water) PT - JOURNAL ARTICLE DA - 880502 DP - 1987 Oct IS - 0304-4602 TA - Ann Acad Med Singapore PG - 586-90 SB - M CY - SINGAPORE IP - 4 VI - 16 JC - 53F AA - Author EM - 8807 AB - The degree of leptospirosis risk was investigated in 80 sewer and 120 public cleansing workers. They were interviewed and their serum samples tested for the presence of leptospiral antibodies by the sensitised erythrocyte lysis (SEL) test. Another 100 control subjects matched by sex, age and ethnic group were similarly studied. The study subjects had higher seroprevalence than the controls--over six times higher for SEL titres of greater than 1:100 and over 1.5 times for titres of greater than 1:25. The highest seroprevalence was found in workers cleaning wet markets and food centres. There was no significant correlation between the prevalence of positive titres and symptom prevalence or hospitalisation. Five of the study subjects (all sewer workers) gave a history of jaundice. AD - Department of Industrial Health, Ministry of Labour, Singapore. PMID- 3446001 CU - 91 SO - Ann Acad Med Singapore 1987 Oct;16(4):586-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 88147225 AU - Niikura M AU - Ono E AU - Yanagawa R TI - Molecular comparison of antigens and proteins of virulent and avirulent clones of Leptospira interrogans serovar copenhageni, strain Shibaura. LA - Eng MH - Antigens, Bacterial/*analysis MH - Bacterial Proteins/*analysis MH - Comparative Study MH - Electrophoresis, Polyacrylamide Gel MH - Immunoassay MH - Leptospira interrogans/*immunology/pathogenicity MH - Molecular Weight MH - Support, Non-U.S. Gov't MH - Virulence RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE DA - 880325 DP - 1987 Oct IS - 0176-6724 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 453-62 SB - M CY - GERMANY, WEST IP - 3-4 VI - 266 JC - Y55 AA - Author EM - 8806 AB - The antigens and the protein profiles of virulent and avirulent clones of Leptospira interrogans serovar copenhageni, strain Shibaura were compared by SDS-polyacrylamide gel electrophoresis (SDS-PAGE), Western blotting and radioimmunoprecipitation. An antigen specific to the virulent clone was detectable only in the virulent clone by Western blotting using anti-virulent clone but not anti-avirulent clone antisera. The molecular weight of the antigen was estimated to be approximately 32000 by SDS-PAGE, and the antigen was found to be thermostable. A 43000 dalton antigenic molecule was found to be specific for the virulent clone, and the 41000 dalton antigenic molecule was found to be specific for the avirulent clone by Western blotting using both anti-virulent and anti-avirulent clones antisera. Therefore, these antigenic molecules seemed to contain at least one antigenic determinant which is common to the virulent and the avirulent clones. No difference between the virulent and avirulent clones was observed in the comparison of protein profiles on SDS-PAGE and surface exposed antigenic protein profiles on radioimmunoprecipitation using radioiodinated leptospiral surface exposed proteins. Therefore, the antigens which were different between the virulent and avirulent clones were suspected not to be protein antigens. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. PMID- 3439384 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 Oct;266(3-4):453-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 88146531 AU - Ito T AU - Yanagawa R TI - Leptospiral attachment to extracellular matrix of mouse fibroblast (L929) cells. LA - Eng MH - Animal MH - Bacterial Adhesion MH - Cell Line MH - Extracellular Matrix/*microbiology MH - Fibroblasts MH - IgG/immunology MH - Immunoglobulins, Fab/immunology MH - Leptospira interrogans/*physiology/pathogenicity MH - Mice MH - Temperature MH - Virulence RN - 0 (Immunoglobulins, Fab) PT - JOURNAL ARTICLE DA - 880325 DP - 1987 Oct IS - 0378-1135 TA - Vet Microbiol PG - 89-96 SB - M CY - NETHERLANDS IP - 1-2 VI - 15 JC - XBW AA - Author EM - 8806 AB - The attachment of leptospires to the extracellular matrix (ECM) remaining after mouse fibroblast (L929) cells on coverslips had been solubilized with Triton X-100 was examined. Each highly virulent line of Leptospira interrogans serovar copenhageni, canicola and pomona attached to ECM more effectively than intermediately virulent and avirulent lines of the same strains, suggesting a correlation between virulence and attachment to ECM. Inhibition of the attachment of highly virulent copenhageni to ECM was found in the presence of the homologous immunoglobulin G Fab fragment. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. PMID- 3439019 CU - 91 SO - Vet Microbiol 1987 Oct;15(1-2):89-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 88146530 AU - Millar BD AU - Chappel RJ AU - Adler B AU - Driesen SJ AU - Jones RT TI - Effect of maternal vaccination on the susceptibility of growing pigs to leptospiral infection. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Colostrum/immunology MH - Female MH - *Immunity, Maternally-Acquired MH - Leptospirosis/immunology/prevention & control/*veterinary MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*immunology/prevention & control MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 880325 DP - 1987 Oct IS - 0378-1135 TA - Vet Microbiol PG - 79-87 SB - M CY - NETHERLANDS IP - 1-2 VI - 15 JC - XBW AA - Author EM - 8806 AB - Serum samples were collected from 30 piglets, derived from 17 litters, whose dams had been vaccinated against leptospirosis. Microscopic agglutination test (MAT) titres against Leptospira interrogans serovar pomona varied greatly from pig to pig; there was less variation among littermates. Titres declined between 4 and 10 weeks of age, with an uncorrected half-life of 15.5 days, consistent with IgG being the main antibody class involved. Twelve pigs, 4 derived from unvaccinated sows and 8 from sows vaccinated against leptospirosis, were challenged intravenously at 8 weeks of age with leptospires of serovar pomona. Colostrum-derived antibody protected 4 out of 8 pigs, and in 1 of the remaining 4 the serological response was reduced. Three of the protected pigs showed reduced serological responses and in the fourth the response was strong, but delayed. All of the pigs derived from unvaccinated sows developed leptospiraemia and leptospiruria and showed strong serological responses. Protection by colostrum-derived antibody bore an inexact relationship to MAT titre, but a titre of 16 appeared to be sufficient for protection. AD - Department of Agriculture and Rural Affairs, Regional Veterinary Laboratory, Bendigo, Vic., Australia. PMID- 3439018 SO - Vet Microbiol 1987 Oct;15(1-2):79-87 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 88146529 AU - Millar BD AU - Chappel RJ AU - Adler B TI - Detection of leptospires in biological fluids using DNA hybridisation. LA - Eng MH - Animal MH - DNA, Bacterial/*analysis MH - Leptospira interrogans/genetics/*isolation & purification MH - *Nucleic Acid Hybridization MH - Predictive Value of Tests MH - Support, Non-U.S. Gov't MH - Swine RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 880325 DP - 1987 Oct IS - 0378-1135 TA - Vet Microbiol PG - 71-8 SB - M CY - NETHERLANDS IP - 1-2 VI - 15 JC - XBW AA - Author EM - 8806 AB - DNA extracted from Leptospira interrogans serovar pomona was labelled with phosphorus-32 by nick translation and used as a genomic probe to detect leptospiral DNA. The sensitivity of detection in a 10-microliter spot on nylon membranes was 160 pg of leptospiral DNA or 1.1 X 10(3) leptospires and assays with nylon membranes were somewhat more sensitive than assays with nitrocellulose membranes. The probe reacted with the pathogenic hardjo and tarassovi leptospiral serovars, but not with other genera of bacteria. To detect leptospires in body fluids, these were treated to free leptospiral DNA and then concentrated on membranes using a Bio-Dot apparatus. Neither serum nor urine interfered with the assay system. The DNA of leptospires added to pig urine was stable for at least 2 h at room temperature and for at least 20 h at - 20 degrees C. AD - Department of Agriculture and Rural Affairs, Bendigo Regional Veterinary Laboratory, Vic., Australia. PMID- 3439017 CU - 91 SO - Vet Microbiol 1987 Oct;15(1-2):71-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 88132704 AU - Thangkhiew I TI - Cefotaxime for therapy of acute leptospirosis [letter] LA - Eng MH - Acute Disease MH - Adult MH - Case Report MH - Cefotaxime/*therapeutic use MH - Human MH - Leptospirosis/*drug therapy MH - Male RN - 64485-93-4 (Cefotaxime) PT - LETTER DA - 880307 DP - 1987 Oct IS - 0066-4804 TA - Antimicrob Agents Chemother PG - 1656 SB - M CY - UNITED STATES IP - 10 VI - 31 JC - 6HK EM - 8805 PMID- 3435112 CU - 91 SO - Antimicrob Agents Chemother 1987 Oct;31(10):1656 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 88120137 AU - Pupkevich-Diamant IaS AU - Nishevich EB AU - Tormozova NM AU - Ryndich AA AU - Vasilets VV TI - [Present-day clinical course of leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Aged MH - Diagnosis, Differential MH - English Abstract MH - Female MH - Human MH - Jaundice/diagnosis MH - Leptospirosis/diagnosis/*etiology MH - Male MH - Middle Age MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE DA - 880304 DP - 1987 Oct IS - 0023-2149 TA - Klin Med (Mosk) PG - 110-6 CY - USSR IP - 10 VI - 65 JC - KW2 EM - 8805 PMID- 3431037 TT - Sovremennoe klinicheskoe techenie leptospiroza. EA - A SO - Klin Med (Mosk) 1987 Oct;65(10):110-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [85 medline neighbors] UI - 88119843 AU - Ito T AU - Yanagawa R TI - Attachment of antigenic variants of leptospiras to mouse fibroblasts resisting inhibitory effect of anti-parent antiserum. LA - Eng MH - Animal MH - Antigenic Variation MH - *Bacterial Adhesion MH - Cells, Cultured MH - Extracellular Matrix/microbiology MH - Fibroblasts/microbiology MH - Immune Sera/*immunology MH - Leptospira interrogans/*immunology MH - Mice MH - Mice, Inbred BALB C PT - JOURNAL ARTICLE DA - 880316 DP - 1987 Oct IS - 0047-1917 TA - Jpn J Vet Res PG - 251-61 CY - JAPAN IP - 4 VI - 35 JC - KRG EM - 8805 PMID- 3430907 SO - Jpn J Vet Res 1987 Oct;35(4):251-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 88270256 AU - Kitson-Piggot AW AU - Prescott JF TI - Leptospirosis in horses in Ontario. LA - Eng MH - Abortion, Veterinary/microbiology MH - Animal MH - Antibodies, Bacterial/*analysis MH - Female MH - Fluorescent Antibody Technique MH - Horse Diseases/*epidemiology MH - Horses MH - Kidney/microbiology MH - Leptospira/*immunology/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Ontario MH - Pregnancy MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880824 DP - 1987 Oct IS - 0830-9000 TA - Can J Vet Res PG - 448-51 SB - M CY - CANADA IP - 4 VI - 51 JC - CKL AA - Author EM - 8810 AB - Sera from Thoroughbred and Standardbred horses in southwest Ontario were tested for antibody to seven Leptospira interrogans serovars (autumnalis, bratislava, canicola, grippotyphosa, hardjo, icterohaemorrhagiae, pomona), using the microscopic agglutination test. There was significantly higher seroprevalence of bratislava than of other serovars, in which prevalence was low. Seroprevalence of bratislava increased significantly with age; only 5% of two to three year old horses had titers greater than or equal to 1:80 compared to 52% of horses older than seven years. Eight of 16 foals from two farms seroconverted at low titers to bratislava between four and eight months of age. Leptospires were not detected by immunofluorescence and isolation techniques in 50 kidneys collected from horses at slaughter. Fetal tissues from 52 aborted horse fetuses were also examined by these methods and serovar kennewicki was identified by immunofluorescence and by isolation in one fetus. Serovar bratislava appears to be widespread in horses in Ontario but unimportant in abortion. The clinical significance of this infection in horses in Ontario is unclear. AD - Department of Veterinary Microbiology and Immunology, Ontario Veterinary College, University of Guelph. PMID- 3330964 CU - 91 SO - Can J Vet Res 1987 Oct;51(4):448-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 88159056 AU - Andrcescu N TI - [Study of leptospirosis in our country, from the early beginnings to the present] LA - Rum MH - History of Medicine, 20th Cent. MH - Human MH - Leptospirosis/*history MH - Romania PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 880419 DP - 1987 Oct-Dec IS - 0376-4494 TA - Rev Ig [Bacteriol] PG - 373-5 CY - ROMANIA IP - 4 VI - 32 JC - S7C EM - 8806 PMID- 3327140 CU - 90 TT - Studiul leptospirozelor in tara noastra, de la primele inceputuri pina in prezent. SO - Rev Ig [Bacteriol] 1987 Oct-Dec;32(4):373-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 88102079 AU - Bernasovskaia EP AU - Kondratenko VN TI - [Epidemiology of icterohemorrhagic leptospirosis (ecological aspects)] LA - Rus MH - Animal MH - *Disease Reservoirs MH - Dogs MH - Ecology MH - Epidemiology/history MH - History of Medicine, 19th Cent. MH - History of Medicine, 20th Cent. MH - Human MH - Leptospira interrogans/pathogenicity MH - Ukraine MH - USSR MH - Weil's Disease/*etiology/transmission MH - Zoonoses/*etiology/transmission PT - HISTORICAL ARTICLE PT - BIOGRAPHY PT - JOURNAL ARTICLE DA - 880224 DP - 1987 Oct IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 43-9 SB - M CY - USSR IP - 10 JC - Y9O EM - 8804 PMID- 3321781 CU - 96 PS - Gromashevskii LV TT - Epidemiologiia ikterogemorragicheskogo leptospiroza (ekologicheskie aspekty). SO - Zh Mikrobiol Epidemiol Immunobiol 1987 Oct;(10):43-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 88147219 AU - Terpstra WJ AU - Korver H AU - Schoone GJ AU - von Leeuwen J AU - Schonemann CE AU - de Jonge-Aglibut S AU - Kolk AH TI - Comparative classification of Leptospira serovars of the Pomona group by monoclonal antibodies and restriction-endonuclease analysis. LA - Eng MH - Antibodies, Monoclonal/diagnostic use MH - Antigens, Bacterial/*analysis MH - Comparative Study MH - DNA Restriction Enzymes MH - DNA, Bacterial/*analysis MH - Electrophoresis, Agar Gel MH - Electrophoresis, Polyacrylamide Gel MH - Leptospira interrogans/*classification/genetics/immunology MH - Serotyping RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 880325 DP - 1987 Oct IS - 0176-6724 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 412-21 SB - M CY - GERMANY, WEST IP - 3-4 VI - 266 JC - Y55 AA - Author EM - 8806 AB - The serovars of the Pomona group of Leptospira interrogans are antigenically closely related and can be classified only with difficulty by conventional typing methods. Monoclonal antibodies (MCAs) were prepared to serovars of the Pomona group. The MCAs were directed against antigens of polysaccharide nature. A battery of six MCAs was selected for the classification of Pomona group reference strains. These MCAs could be used for the typing of all Pomona group strains and unknown isolates. Alternatively, DNA was extracted from the same strains and isolates and digested with restriction enzymes. The patterns that were obtained after gel separation of the DNA digests were characteristic and also allowed classification. Restriction enzyme analysis was complicated but gave detailed information. Classification with MCAs could be easily and rapidly performed. AD - N.H. Swellengrebel Laboratory of Tropical Hygiene, Royal Tropical Institute, Amsterdam, The Netherlands. PMID- 2830738 CU - 93 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 Oct;266(3-4):412-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 88063048 AU - Corn JL AU - Lee RM AU - Erickson GA AU - Murphy CD TI - Serologic survey for evidence of exposure to vesicular stomatitis virus, pseudorabies virus, brucellosis and leptospirosis in collared peccaries from Arizona. LA - Eng MH - Animal MH - Animals, Wild/*immunology/microbiology MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - Arizona MH - Artiodactyla/*immunology/microbiology MH - Brucella/*immunology MH - Herpesvirus 1, Suid/*immunology MH - Leptospira interrogans/classification/*immunology MH - Serotyping/veterinary MH - Support, U.S. Gov't, Non-P.H.S. MH - Vesicular Stomatitis-Indiana Virus/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 880120 DP - 1987 Oct IS - 0090-3558 TA - J Wildl Dis PG - 551-7 SB - M CY - UNITED STATES IP - 4 VI - 23 JC - KEM AA - Author EM - 8803 AB - Two hundred eighteen usable serum samples were collected from hunter- killed collared peccaries (Tayassu tajacu) during March 1986, in three areas of Arizona. Evaluations for antibodies against vesicular stomatitis virus (VSV) New Jersey (NJ) type, VSV Indiana type, pseudorabies virus, brucellosis, and leptospirosis revealed positive test results in 8%, 0%, less than 1%, 0%, and 23% of the sera, respectively. Exposure of peccaries to VSV (NJ) was widespread, but variation in the prevalence of seropositive peccaries was not found between the three areas sampled. The exposure of peccaries to VSV (NJ) probably was related to the recent epizootics in livestock in the vicinity. Exposure to Leptospira interrogans serovars also was widespread, and geographic variation in the prevalence of peccaries with antibodies against L. interrogans was found. AD - Department of Parasitology, College of Veterinary Medicine, University of Georgia, Athens 30602. PMID- 2824864 CU - 93 SO - J Wildl Dis 1987 Oct;23(4):551-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [212 medline neighbors] UI - 88058109 AU - Lewin JC TI - Leptospirosis in Hawaii [editorial] LA - Eng MH - Hawaii MH - Human MH - Leptospirosis/*epidemiology PT - EDITORIAL DA - 880112 DP - 1987 Sep IS - 0017-8594 TA - Hawaii Med J PG - 330 CY - UNITED STATES IP - 9 VI - 46 JC - G1D EM - 8803 PMID- 3679802 CU - 91 SO - Hawaii Med J 1987 Sep;46(9):330 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 88056887 AU - Liang XS AU - Dai BM AU - Bao L TI - [Ultrastructural changes of renal glomeruli in guinea pigs with leptospirosis] LA - Chi MH - Animal MH - English Abstract MH - Freeze Fracturing MH - Guinea Pigs MH - Kidney Glomerulus/*ultrastructure MH - Leptospirosis/*pathology MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 880111 DP - 1987 Sep IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 203-6 CY - CHINA IP - 3 VI - 18 JC - GEB EM - 8803 PMID- 3679167 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1987 Sep;18(3):203-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 87295981 AU - Cacciapuoti B AU - Ciceroni L AU - Maffei C AU - Di Stanislao F AU - Strusi P AU - Calegari L AU - Lupidi R AU - Scalise G AU - Cagnoni G AU - Renga G TI - A waterborne outbreak of leptospirosis. LA - Eng MH - Adult MH - Aged MH - Animal MH - Antibodies, Bacterial/analysis MH - *Disease Outbreaks MH - Epidemiologic Methods MH - Female MH - Hedgehogs/microbiology MH - Human MH - Italy MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology/immunology/transmission MH - Male MH - Middle Age MH - Risk MH - Sex Factors MH - *Water Microbiology MH - Zoonoses/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870910 DP - 1987 Sep IS - 0002-9262 TA - Am J Epidemiol PG - 535-45 SB - M SB - X CY - UNITED STATES IP - 3 VI - 126 JC - 3H3 AA - Author EM - 8711 AB - During the period from July 10-26, 1984, 33 cases of serologically confirmed leptospirosis occurred in a small town in central Italy. The fatality rate, including the deaths of two unconfirmed cases, was 8.6% (3 of 35). Based on serologic evidence, the infection was caused by leptospires of the serogroup Australis. Epidemiologic study showed that the patients contracted the infection by drinking water from a fountain. The source of leptospiral contamination was probably a hedgehog trapped in a reservoir of water not in use but still connected to the water system of the fountain. PMID- 3618584 CU - 91 SO - Am J Epidemiol 1987 Sep;126(3):535-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 88139129 AU - Muthusethupathi MA AU - Shivakumar S TI - Acute renal failure due to leptospirosis. LA - Eng MH - Adult MH - Aged MH - Female MH - Human MH - Kidney Failure, Acute/*microbiology/pathology MH - Leptospirosis/blood/*complications/therapy MH - Male MH - Middle Age MH - Peritoneal Dialysis PT - JOURNAL ARTICLE DA - 880328 DP - 1987 Sep IS - 0004-5772 TA - J Assoc Physicians India PG - 631-3 CY - INDIA IP - 9 VI - 35 JC - HG7 EM - 8806 PMID- 3436932 SO - J Assoc Physicians India 1987 Sep;35(9):631-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 88063200 AU - Ahmed IP TI - Serological studies on leptospirosis in Pakistan. LA - Eng MH - Animal MH - Animals, Domestic/*immunology MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology/immunology/veterinary MH - Pakistan MH - Rats MH - Rodentia/immunology MH - Shrews/immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 871230 DP - 1987 Sep IS - 0030-9982 TA - JPMA J Pak Med Assoc PG - 233-6 CY - PAKISTAN IP - 9 VI - 37 JC - KGI EM - 8803 PMID- 3119890 CU - 91 SO - JPMA J Pak Med Assoc 1987 Sep;37(9):233-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 88083704 AU - Smirnov AN TI - [Hemorrhagic fever with renal syndrome] LA - Rus MH - Acute Disease MH - Case Report MH - Diagnosis, Differential MH - Hemorrhagic Fever with Renal Syndrome/*diagnosis/pathology MH - Hemorrhagic Fever, Crimean/diagnosis MH - Hemorrhagic Fever, Omsk/diagnosis MH - Human MH - Influenza/diagnosis MH - Leptospirosis/diagnosis MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 880205 DP - 1987 Sep IS - 0014-9772 TA - Feldsher Akush PG - 57-9 SB - N CY - USSR IP - 9 VI - 52 JC - EVA EM - 8804 PMID- 2891573 CU - 94 LI - N TT - Gemorragicheskaia likhoradka s pochechnym sindromom. SO - Feldsher Akush 1987 Sep;52(9):57-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 88076711 AU - Jones RT AU - Millar BD AU - Chappel RJ AU - Adler B TI - Macroscopic kidney lesions in slaughtered pigs are an inadequate indicator of current leptospiral infection. LA - Eng MH - Animal MH - Female MH - Kidney/*pathology MH - Leptospirosis/diagnosis/pathology/*veterinary MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/microbiology/*pathology PT - JOURNAL ARTICLE DA - 880105 DP - 1987 Aug IS - 0005-0423 TA - Aust Vet J PG - 258-9 SB - M CY - AUSTRALIA IP - 8 VI - 64 JC - 9IE EM - 8803 AD - Department of Agriculture and Rural Affairs, Regional Veterinary Laboratory, Bendigo, Victoria. PMID- 3689266 SO - Aust Vet J 1987 Aug;64(8):258-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 88064040 AU - Shugailo VT AU - Dorofeev SM AU - Baklanova AV AU - Tishchenko AN AU - Ornatskaia SA TI - [Clinical characteristics of leptospirosis and various indicators of liver function] LA - Rus MH - Adult MH - English Abstract MH - Human MH - Liver/*physiopathology MH - Liver Function Tests MH - Male MH - Middle Age MH - Weil's Disease/*physiopathology PT - JOURNAL ARTICLE DA - 880104 DP - 1987 Aug IS - 0023-2149 TA - Klin Med (Mosk) PG - 105-8 CY - USSR IP - 8 VI - 65 JC - KW2 EM - 8803 PMID- 3682713 TT - Klinicheskie osobennosti leptospiroza i nekotorye pokazateli funktsional'nogo sostoianiia pecheni. EA - A SO - Klin Med (Mosk) 1987 Aug;65(8):105-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 87276274 AU - Little TW AU - Stevens AE AU - Hathaway SC TI - Serological studies of British leptospiral isolates of the Sejroe serogroup. III. The distribution of leptospires of the Sejroe serogroup in the British Isles. LA - Eng MH - Animal MH - Cattle/microbiology MH - Great Britain MH - Human MH - Leptospira/classification/immunology/*isolation & purification MH - Leptospira interrogans/immunology MH - Mice/microbiology MH - Serotyping MH - Sheep/microbiology MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 870921 DP - 1987 Aug IS - 0950-2688 TA - Epidemiol Infect PG - 117-26 SB - M CY - ENGLAND IP - 1 VI - 99 JC - EPI AA - Author EM - 8711 AB - Some 94 strains of leptospires belonging to the Sejroe serogroup isolated in the British Isles were identified to the serovar level using specific factor sera. Seventy strains were identified as Leptospira interrogans serovar hardjo, 66 from cattle, 2 from pigs and 1 each from a sheep foetus and a human. Twenty-four strains were identified as L. interrogans serovar saxkoebing, most strains were isolated from either wood mice, bank or field voles but strains were also isolated from badgers, a fox and a dog. PMID- 3609169 SO - Epidemiol Infect 1987 Aug;99(1):117-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 87276273 AU - Little TW AU - Stevens AE AU - Hathaway SC TI - Serological studies on British isolates of the Sejroe serogroup of leptospira. II. An evaluation of the factor analysis method of identifying leptospires using strains belonging to the Sejroe serogroup. LA - Eng MH - Agglutination Tests MH - Factor Analysis, Statistical MH - Great Britain MH - Human MH - Immune Sera/immunology MH - Leptospira/classification/*immunology MH - Leptospira interrogans/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 870921 DP - 1987 Aug IS - 0950-2688 TA - Epidemiol Infect PG - 107-15 SB - M CY - ENGLAND IP - 1 VI - 99 JC - EPI AA - Author EM - 8711 AB - Twelve British isolates of leptospira belonging to the Sejroe serogroup were examined using a series of six factor sera prepared by a number of different absorption methods. Ten of the isolates were identified as Leptospira interrogans serovar hardjo and two as L. interrogans serovar saxkoebing. These isolates had previously been identified using the cross agglutination absorption method. PMID- 3609168 SO - Epidemiol Infect 1987 Aug;99(1):107-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 88102041 AU - Kmety E AU - Gurycova D AU - Jarekova J AU - Rehacek J TI - [Effort to eradicate a focus of tularemia and leptospirosis] LA - Ger MH - Animal MH - Czechoslovakia MH - Disease Outbreaks/prevention & control/*veterinary MH - *Disease Reservoirs MH - English Abstract MH - Human MH - Leptospirosis/epidemiology/prevention & control/*veterinary MH - *Mammals MH - Phosphines MH - Rodent Control MH - Rodenticides MH - Tularemia/epidemiology/prevention & control/*veterinary MH - Zinc RN - 0 (Phosphines) RN - 0 (Rodenticides) RN - 1314-84-7 (zinc phosphide) RN - 7440-66-6 (Zinc) PT - JOURNAL ARTICLE DA - 880202 DP - 1987 Aug IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 249-54 SB - M CY - GERMANY, WEST IP - 1-2 VI - 266 JC - Y55 AA - Author EM - 8804 AB - An endemic area of tularemia and field fever was submitted to a complex surveillance over a period of more than 10 years. In 1977 an epizootic outbreak of tularemia appeared in all four localities studied. The infection rate in small mammals exceeded 10%. F. tularensis was isolated also from different species of ectoparasites. During 1978 the epizootic stopped in 3 foci, but continued to spread in one. Rodenticides (zinc phosphide) were therefore applied in this focus twice annually for 2 1/2 years. Since 1978, tularemia infections disappeared in small mammals as well as in man. The application of rodenticides did not influence the circulation of Leptospira grippotyphosa in small mammals. Their infection rate ranged between 3 and 6%. The reason for this striking difference is seen in the different pathogenesis and transmission of both infections. AD - Institut fur Epidemiologie, Medizinische Fakultat der Komensky- Universitat, CSSR. PMID- 3425030 CU - 92 TT - Versuch der Tilgung eines Naturherdes der Tularamie und der Leptospirose. EA - A SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 Aug;266(1-2):249-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 88099566 AU - Chan OY AU - Paul DR AU - Sng EH TI - Leptospirosis among abattoir workers--a serological survey. LA - Eng MH - *Abattoirs MH - Antibodies, Bacterial/analysis MH - Hospitalization MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology/immunology MH - Occupational Diseases/*epidemiology/immunology MH - Risk Factors MH - Singapore RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880205 DP - 1987 Aug IS - 0037-5675 TA - Singapore Med J PG - 293-6 CY - SINGAPORE IP - 4 VI - 28 JC - URI EM - 8804 PMID- 3423792 CU - 91 SO - Singapore Med J 1987 Aug;28(4):293-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 88064058 AU - Pupkevich-Diamant IaS TI - [Various forgotten and little-known facts in the history of studies on leptospirosis] LA - Rus MH - History of Medicine, 19th Cent. MH - History of Medicine, 20th Cent. MH - Human MH - Leptospirosis/*history MH - Russia (Pre-1917) MH - USSR PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 880104 DP - 1987 Aug IS - 0023-2149 TA - Klin Med (Mosk) PG - 146-51 CY - USSR IP - 8 VI - 65 JC - KW2 EM - 8803 PMID- 3316830 CU - 90 TT - Nekotorye zabytye i maloizvestnye fakty v istorii izucheniia leptospiroznoi infektsii. SO - Klin Med (Mosk) 1987 Aug;65(8):146-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 87308724 AU - Anderson JF AU - Johnson RC AU - Magnarelli LA AU - Hyde FW AU - Andreadis TG TI - New infectious spirochete isolated from short-tailed shrews and white- footed mice. LA - Eng MH - Animal MH - Connecticut MH - Fluorescent Antibody Technique MH - Hamsters MH - Kidney/microbiology MH - Mice MH - Microscopy, Electron MH - Minnesota MH - Peromyscus/*microbiology MH - Rodent Diseases/*microbiology MH - Shrews/*microbiology MH - Spirochaetales/classification/*isolation & purification/ultrastructure MH - Spirochaetales Infections/microbiology/*veterinary MH - Spleen/microbiology MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE ID - AI18153/AI/NIAID ID - AR34744/AR/NIAMS DA - 871021 DP - 1987 Aug IS - 0095-1137 TA - J Clin Microbiol PG - 1490-4 SB - M CY - UNITED STATES IP - 8 VI - 25 JC - HSH AA - Author EM - 8712 AB - A spirochete with two periplasmic flagella was isolated from the blood or tissues of spleens and kidneys from short-tailed shrews (Blarina brevicauda) and white-footed mice (Peromyscus leucopus) in Connecticut and Minnesota. After inoculation, the shrew-mouse spirochete infected Swiss mice and Syrian hamsters. This spirochete is morphologically and serologically distinct from the species of Treponema, Borrelia, Leptospira, and Spirochaeta examined. PMID- 3305565 CU - 96 SO - J Clin Microbiol 1987 Aug;25(8):1490-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 88102037 AU - Saito T AU - Ono E AU - Yanagawa R TI - Enzyme activities of the strains belonging to family Leptospiraceae detected by the API ZYM system. LA - Eng MH - gamma-Glutamyltransferase/metabolism MH - Amino Acid Naphthylamidases/*metabolism MH - Esterases/*metabolism MH - Glycoside Hydrolases/*metabolism MH - Leptospira/classification/*enzymology MH - Leptospira interrogans/classification/enzymology MH - Spirochaetaceae/classification/*enzymology RN - EC 2.3.2.2 (gamma-Glutamyltransferase) RN - EC 3.1. (Esterases) RN - EC 3.2.1. (Glycoside Hydrolases) RN - EC 3.4.11. (Amino Acid Naphthylamidases) PT - JOURNAL ARTICLE DA - 880202 DP - 1987 Aug IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 218-25 SB - M CY - GERMANY, WEST IP - 1-2 VI - 266 JC - Y55 AA - Author EM - 8804 AB - A total of 32 strains of the family Leptospiraceae (23 strains of Leptospira interrogans, 6 strains of Leptospira biflexa, 2 strains of Leptonema and 1 strain of Leptospira parva) were examined for enzyme activities using 89 substrates (API ZYM system). More than 90% of the strains belonging to the family Leptospiraceae possessed strong activities of beta-D-galactosidase, beta-D-glucosidase and 5 esterases (C5, C6, C8, C9 and C10). More than 90% of the strains belonging to the genus Leptospira, except L. parva, had strong activities of L-lysine arylamidase and alpha-L-glutamate arylamidase. L. biflexa strains, except serovar andamana, were different from the other strains examined in that they possessed glycyl-glycine arylamidase, glycyl-phenylalanine arylamidase and L-tryptophan arylamidase. L. biflexa strains, except andamana, L. parva and Leptonema strains possessed strong activities of glycine arylamidase and leucyl-glycine arylamidase. Two strains of the genus Leptonema were different from the strains belonging to the genus Leptospira in that they possessed strong activities of beta-D- lactosidase. L. parva lacked alpha-D-galactosidase which other strains belonging to the family Leptospiraceae possessed. Dendrogram analysis revealed that strains belonging to the family Leptospiraceae were divided into 4 groups. The first group consisted of all strains belonging to L. interrogans and serovar andamana of L. biflexa; the second group consisted of the remaining 5 serovars of L. biflexa; the third group consisted of the genus Leptonema; and the fourth group consisted of only L. parva. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. PMID- 2892326 CU - 94 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 Aug;266(1-2):218-25 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 88034437 AU - Luzzi GA AU - Milne LM AU - Waitkins SA TI - Rat-bite acquired leptospirosis. LA - Eng MH - Animal MH - Bites and Stings/*complications MH - Case Report MH - Child MH - Human MH - Male MH - *Muridae MH - Weil's Disease/*transmission PT - JOURNAL ARTICLE DA - 871124 DP - 1987 Jul IS - 0163-4453 TA - J Infect PG - 57-60 SB - M CY - ENGLAND IP - 1 VI - 15 JC - IG9 AA - Author EM - 8802 AB - We report a case of leptospirosis in a boy following a rat-bite, an unusual mode of transmission for this infection. The use of antibiotics for fever following a rat-bite is discussed. AD - Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford. PMID- 3668265 SO - J Infect 1987 Jul;15(1):57-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 88003888 AU - Lin JR TI - [Studies on the indirect haemagglutination test with Leptospira] LA - Chi MH - English Abstract MH - *Hemagglutination Tests MH - Human MH - Leptospira/*immunology MH - Leptospirosis/diagnosis PT - JOURNAL ARTICLE DA - 871105 DP - 1987 Jul IS - 0253-9624 TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 212-4 CY - CHINA IP - 4 VI - 21 JC - D74 EM - 8801 PMID- 3652871 EA - A SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1987 Jul;21(4):212-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 87306653 AU - Krampitz HE AU - Bark S TI - [Epidemiology of Ixodes-Borreliosis in Southern Germany] LA - Ger MH - Animal MH - Antibodies/immunology MH - Borrelia Infections/epidemiology/*immunology MH - Cattle/immunology MH - Dogs/immunology MH - English Abstract MH - Germany, West MH - Host-Parasite Relations MH - Lyme Disease/*immunology MH - Muridae/blood/immunology MH - Protozoa/immunology MH - Ticks/*parasitology RN - 0 (Antibodies) PT - JOURNAL ARTICLE DA - 871022 DP - 1987 Jul IS - 0340-1162 TA - Immun Infekt PG - 141-5 SB - M CY - GERMANY, WEST IP - 4 VI - 15 JC - GH1 AA - Author EM - 8712 AB - Intimate adaptation occurs between European strains of Borrelia burgdorferi and the local hard tick Ixodes ricinus. I. dammini, the important vector in USA, could not be infected experimentally with a strain of the lyme spirochete from Southern Germany. Other species of blood suckers are sometimes able to maintain uptaken spirochetes for a few days, but never to compensate the tick vector. Man seems to be a good host for B. burgdorferi but without epidemiological significance due to his poor vector role for ticks. The Ixodes-borreliosis is an anthropozoonosis. Well-known animal hosts for the three life stages of the tick are possible carrier hosts for B. burgdorferi as well. It has been established here for the first time in Europe that common wild- rodent species may be of some significance as hosts for the spirochete, as it is well-known in North America. Serological evidence shows, that dogs and grasing cattle in Southern Germany seem to play an important role in B. burgdorferi's outdoor circulation. 36 out of 72 dogs (= 50%) and 22 out of 66 cattle (= 33%) reacted significantly positive in the IFAT if local strains of B. burgdorferi were used as antigen. No serological cross reactions have been observed with Leptospira infections in dogs and cattles. PMID- 3623604 CU - 91 TT - Zur Epidemiologie der Ixodes-Borreliose in Suddeutschland. EA - A SO - Immun Infekt 1987 Jul;15(4):141-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 88208748 AU - Manev H AU - Gancheva E AU - Yanakieva M TI - The etiology and epidemiology of the leptospirosis in Bulgaria. LA - Eng MH - Animal MH - Animals, Domestic MH - Animals, Wild MH - Bulgaria MH - Disease Reservoirs MH - Disease Vectors MH - Human MH - Leptospira/classification/isolation & purification MH - Leptospirosis/epidemiology/*etiology MH - Serotyping PT - JOURNAL ARTICLE DA - 880531 DP - 1987 Jul-Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 233-9 CY - ROMANIA IP - 3 VI - 46 JC - 8EM EM - 8808 PMID- 3449017 CU - 88 SO - Arch Roum Pathol Exp Microbiol 1987 Jul-Sep;46(3):233-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 88145182 AU - Koury MC AU - Cisalpino EO TI - Complement fixation and haemagglutination reaction with methanol extracts of icterohaemorrhagiae, canicola and patoc leptospires serovars. LA - Eng MH - Alcohol, Methyl MH - Antigens, Bacterial/*immunology/isolation & purification MH - *Complement Fixation Tests MH - *Hemagglutination Tests MH - Human MH - Leptospira/classification/*immunology MH - Species Specificity RN - 0 (Antigens, Bacterial) RN - 67-56-1 (Alcohol, Methyl) PT - JOURNAL ARTICLE DA - 880328 DP - 1987 Jul-Sep IS - 0034-9771 TA - Rev Latinoam Microbiol PG - 283-6 CY - MEXICO IP - 3 VI - 29 JC - SEP EM - 8806 PMID- 3438608 CU - 91 SO - Rev Latinoam Microbiol 1987 Jul-Sep;29(3):283-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 87252387 AU - Magnarelli LA AU - Anderson JF AU - Johnson RC TI - Cross-reactivity in serological tests for Lyme disease and other spirochetal infections. LA - Eng MH - Antibodies, Bacterial/*immunology MH - Cross Reactions MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique MH - Human MH - Lyme Disease/diagnosis/*immunology MH - Serodiagnosis MH - Spirochaetales Infections/diagnosis/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870804 DP - 1987 Jul IS - 0022-1899 TA - J Infect Dis PG - 183-8 SB - A SB - M CY - UNITED STATES IP - 1 VI - 156 JC - IH3 AA - Author EM - 8710 AB - Serum specimens from 163 persons with Lyme disease, tick-borne or louse- borne relapsing fever, yaws, syphilis, leptospirosis, or Rocky Mountain spotted fever were analyzed to assess the specificity of indirect fluorescent antibody (IFA) tests, an enzyme-linked immunosorbent assay (ELISA), and microscopic agglutination (MA) procedures. Strong cross- reactivity occurred when sera from individuals with Lyme disease, tick- borne relapsing fever, and louse-borne relapsing fever were tested against heterologous Borrelia antigens. Antibodies to Borrelia burgdorferi bound to Treponema pallidum in immunofluorescence tests for syphilis. Sera from subjects with syphilis cross-reacted in IFA tests and the ELISA for Lyme disease. Immunoglobulin antibodies to Borrelia or Treponema spirochetes, however, did not react with serovars of Leptospira interrogans in MA or IFA tests, and the prevalence of false- positive results in the reciprocal analyses was negligible. PMID- 3298452 CU - 91 SO - J Infect Dis 1987 Jul;156(1):183-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 88045239 AU - Saito T AU - Ono E AU - Yanagawa R AU - Cacciapuoti B AU - Ciceroni L TI - Selection of antigenic variants from Leptospira interrogans serovar canicola by means of anti-canicola monoclonal antibody. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Monoclonal/*immunology MH - Antigens, Bacterial/isolation & purification MH - Epitopes/*isolation & purification MH - Leptospira interrogans/classification/*immunology MH - Leptospirosis/*immunology MH - Serotyping RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 871216 DP - 1987 Jul IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 290-8 SB - M CY - GERMANY, WEST IP - 3-4 VI - 265 JC - Y55 AA - Author EM - 8802 AB - Antigenic variants were isolated from canicola by a single selection with anti-canicola monoclonal antibody CT-3. The variants were not identical to any serovars of serogroup Canicola and thought to be a new serovar. Variation frequency was calculated at 5.9 X 10(-4). The usefulness of monoclonal antibodies for selection of antigenic variants of leptospiras is discussed. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. PMID- 2445125 CU - 95 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 Jul;265(3-4):290-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 87268314 AU - el Harith A AU - Laarman JJ AU - Minter-Goedbloed E AU - Kager PA AU - Kolk AH TI - Trypsin-treated and coomassie blue-stained epimastigote antigen in a microagglutination test for Chagas' disease. LA - Eng MH - *Agglutination Tests MH - Antibodies/*analysis MH - Antigens, Protozoan/*immunology MH - Chagas Disease/*diagnosis/immunology MH - Cross Reactions MH - Human MH - Leishmania donovani/immunology MH - Mercaptoethanol/pharmacology MH - Rosaniline Dyes MH - Staining MH - Support, Non-U.S. Gov't MH - Trypanosoma cruzi/*immunology MH - Trypsin/pharmacology RN - EC 3.4.21.4 (Trypsin) RN - 0 (Antibodies) RN - 0 (Antigens, Protozoan) RN - 0 (Rosaniline Dyes) RN - 60-24-2 (Mercaptoethanol) RN - 6104-58-1 (coomassie Brilliant Blue) PT - JOURNAL ARTICLE DA - 870820 DP - 1987 Jul IS - 0002-9637 TA - Am J Trop Med Hyg PG - 66-71 SB - A SB - M CY - UNITED STATES IP - 1 VI - 37 JC - 3ZQ AA - Author EM - 8710 AB - A microagglutination test using trypsin-treated and Coomassie blue- stained Trypanosoma cruzi epimastigote antigen was adapted for the diagnosis of Chagas' disease. When incorporated in the test, 2- mercaptoethanol treatment of chagasic sera had no influence on antibody titer. In contrast, titers in sera from patients with visceral leishmaniasis, African trypanosomiasis, and autoimmune disorders, subjected to similar treatment, showed remarkable decline. Accordingly, a lower cut-off point for Chagas' disease serological negativity could be taken resulting in a higher sensitivity (95.6%); the specificity was 94.7%. Similar specificities were obtained with Leishmania donovani chagasi and L. d. donovani antigens applied to homologous visceral leishmaniasis and heterologous Chagas' sera. Of 316 nonchagasic sera, only 3 with leptospirosis and 1 with leprosy showed seropositive titers prior to and after 2-mercaptoethanol treatment. PMID- 2440329 CU - 95 SO - Am J Trop Med Hyg 1987 Jul;37(1):66-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 88045215 AU - Palmer MF AU - Waitkins SA AU - Wanyangu SW TI - A comparison of live and formalised leptospiral microscopic agglutination test. LA - Eng MH - *Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial/*immunology MH - Comparative Study MH - Cross Reactions MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Predictive Value of Tests RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 871202 DP - 1987 Jun IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 151-9 SB - M CY - GERMANY, WEST IP - 1-2 VI - 265 JC - Y55 AA - Author EM - 8802 AB - The sensitivity and reliability of a formalised leptospiral antigen battery was compared with a smaller battery of live leptospiral antigens with 152 human sera positive for leptospirosis. There was good concurrence of results between the formalised and live antigens, however the live battery did fail to detect some positive sera where the antibody level was low. The formalised antigens were more sensitive than the live (P less than 0.001) and more reliable in the detection of early leptospiral infection, but the live antigens were more specific in the determination of probable infecting serogroup. AD - PHLS Leptospira Reference Unit/WHO/FAO Collaborating Centre for Research and Reference on Leptospirosis, County Hospital, Hereford, United Kingdom. PMID- 3673329 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 Jun;265(1-2):151-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 87321358 AU - Wu SH AU - Jiang SX AU - Wang HQ AU - Ke L AU - Nie DK AU - Zhu GF AU - Liu YM TI - [Studies on endotoxins of Leptospira. III. The presence of beta-hydroxy- myristic acid in the LPS of Leptospira interrogans serovar Lai] LA - Chi MH - Chromatography, Gas MH - Chromatography, Thin Layer MH - Endotoxins/*analysis MH - English Abstract MH - Leptospira interrogans/*analysis MH - Lipopolysaccharides/analysis MH - Myristic Acids/*analysis RN - 0 (Endotoxins) RN - 0 (Lipopolysaccharides) RN - 0 (Myristic Acids) RN - 1961-72-4 (beta-hydroxymyristic acid) PT - JOURNAL ARTICLE DA - 871014 DP - 1987 Jun IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 165-8 CY - CHINA IP - 2 VI - 27 JC - XNA EM - 8712 PMID- 3630144 CU - 92 EA - A SO - Wei Sheng Wu Hsueh Pao 1987 Jun;27(2):165-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 87316440 AU - De Lange JF AU - Gummow B AU - Turner GV AU - Redman AR TI - The isolation of Leptospira interrogans serovar pomona and related serological findings associated with a mixed farming unit in the Transvaal. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle/immunology MH - Dogs/immunology MH - Horses/immunology MH - Leptospira interrogans/immunology/*isolation & purification MH - Serodiagnosis MH - Sheep/immunology MH - South Africa MH - Swine/immunology MH - Swine Diseases/*microbiology MH - Weil's Disease/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870928 DP - 1987 Jun IS - 0030-2465 TA - Onderstepoort J Vet Res PG - 119-21 SB - M CY - SOUTH AFRICA IP - 2 VI - 54 JC - OI6 AA - Author EM - 8712 AB - This is the first known isolation in the Republic of South Africa (RSA) of the serovar pomona from the organs of porcine foetuses as well as from the renal lymph nodes of slaughter pigs showing chronic nephritis. In addition, the serovar pomona was isolated from the kidneys of 87.5% of the slaughter pigs examined. The success of these isolations was attributed in part to the refining of 2 existing isolation techniques which complement each other. Using the microscopic agglutination test, serum samples taken from the same farming unit showed evidence of antibodies to the serovar pomona in 89 out of the 170 bovines (52%), 9 out of the 52 porcines (17%), 2 of the 2 canines (100%), 5 out of the 13 equines (38%) and 2 out of the 152 ovines (1%) that were tested. As far as is known, serological evidence of the serovar pomona in porcines, ovines, equines and canines has never previously been published in the RSA. PMID- 3627726 CU - 91 SO - Onderstepoort J Vet Res 1987 Jun;54(2):119-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 87300888 AU - Bakoss P AU - Kmety E AU - Machacova E AU - Stupalova S AU - Slacikova M AU - Jarekova J TI - [Surveillance of leptospirosis in Slovakia] LA - Slo MH - Adolescence MH - Adult MH - Aged MH - Aged, 80 and over MH - Child MH - Child, Preschool MH - Czechoslovakia MH - English Abstract MH - Female MH - Human MH - Leptospira/classification MH - Leptospirosis/*epidemiology/microbiology MH - Male MH - Middle Age MH - Serotyping PT - JOURNAL ARTICLE DA - 870928 DP - 1987 Jun IS - 0006-9248 TA - Bratisl Lek Listy PG - 696-709 CY - CZECHOSLOVAKIA IP - 6 VI - 87 JC - B5N EM - 8712 PMID- 3621004 CU - 88 TT - Surveillance leptospiroz v SSR. EA - A SO - Bratisl Lek Listy 1987 Jun;87(6):696-709 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [52 medline neighbors] UI - 87299450 AU - Thompson JC AU - Johnstone AC TI - The effects of gamma-irradiation on haemopoiesis and red blood cell destruction in hamsters infected with Leptospira interrogans serovar ballum. LA - Eng MH - Animal MH - Bone Marrow/pathology MH - Erythrocyte Aging/*radiation effects MH - Erythrocytes/ultrastructure MH - Gamma Rays MH - Hamsters MH - Hematopoiesis/*radiation effects MH - Hemoglobins/analysis MH - Kidney/pathology MH - Liver/pathology MH - Mesocricetus MH - Microscopy, Electron, Scanning MH - Spleen/pathology MH - Weil's Disease/*blood/pathology PT - JOURNAL ARTICLE DA - 871008 DP - 1987 Jun IS - 0007-1021 TA - Br J Exp Pathol PG - 389-98 SB - M CY - ENGLAND IP - 3 VI - 68 JC - AWW AA - Author EM - 8712 AB - Irradiated hamsters were infected with Leptospira interrogans serovar ballum in order to study the effects of impairment of the reticulo- macrophage system on the progression of the disease and the development of haemoglobinaemia. Infected and irradiated hamsters were compared with infected controls, irradiated controls and untreated controls. Red blood cells (RBCs) from untreated controls were biconcave disks while those from irradiated controls were echinocytes. Red blood cells from animals of both infected groups which were severely affected and moribund were in the form of pitted spherocytes and were associated with increased icteric indices and haemoglobinaemia. Red blood cells from less severely affected animals were echinocytic. Pitted spherocytes, however, were seen in some irradiated-infected hamsters before increased icteric indices and haemoglobinaemia were present. Both irradiated-infected and irradiated hamsters showed severe depletion of haemopoietic cells and lymphoid cells, with regeneration occurring in those animals which survived for longer. Red cell sequestration and erythrophagocytosis were present in infected-only hamsters. In irradiated-infected animals, severe anaemia was caused by both persistence of fixed macrophages, RBC sequestration and erythrophagocytosis, and haemorrhage due to vascular damage and renal papillary necrosis. A severe leucopaenia affected the irradiated hamsters' ability to suppress leptospiral multiplication resulting in the presence of larger numbers of organisms. PMID- 3620332 CU - 90 SO - Br J Exp Pathol 1987 Jun;68(3):389-98 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 87276411 AU - Cacciapuoti B AU - Vellucci A AU - Ciceroni L AU - Pinto A AU - Taggi F TI - Prevalence of leptospirosis in man. Pilot survey. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Child MH - Child, Preschool MH - Female MH - Human MH - Italy MH - Leptospira/classification/immunology MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Pilot Projects MH - Rural Population MH - Urban Population RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870923 DP - 1987 Jun IS - 0392-2990 TA - Eur J Epidemiol PG - 137-42 SB - M CY - ITALY IP - 2 VI - 3 JC - ERE AA - Author EM - 8711 AB - A survey on the prevalence of leptospirosis was performed on the population living in an area of central Italy. The size of the sample was calculated in order to provide significant results in the case of a prevalence of infection in not less than 1% of the population. Results demonstrated an unexpectedly wide circulation of leptospirosis in the surveyed area, showing a prevalence rate of infection of 11.34% for people living in rural areas and 3.08% for people living in the main town. The highest prevalence of infection (17.44%) was found in people between 30 and 44 years of age, living in rural areas. Such a wide circulation of undiagnosed past leptospiral infections was attributed both to the prevalence of mild clinical cases of leptospirosis in humans and the lack of microbiological tests performed to differentiate current leptospirosis from other infectious illnesses. An unexpected persistence in sera of co-agglutinins towards non-pathogenic serovars of L. biflexa was also noticed in healthy people. Criteria were established for the extension of the survey on the prevalence of leptospirosis to cover larger areas by limiting sampling to the more exposed age groups and to areas representative of a larger land belt. PMID- 3609247 CU - 91 SO - Eur J Epidemiol 1987 Jun;3(2):137-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 87268829 AU - Caspi D AU - Snel FW AU - Batt RM AU - Bennett D AU - Rutteman GR AU - Hartman EG AU - Baltz ML AU - Gruys E AU - Pepys MB TI - C-reactive protein in dogs. LA - Eng MH - Animal MH - Arthritis, Rheumatoid/blood/veterinary MH - C-Reactive Protein/*analysis MH - Caseins/pharmacology MH - Dog Diseases/*blood MH - Dogs/*blood/surgery MH - Female MH - Leptospirosis/blood/veterinary MH - Malabsorption Syndromes/blood/veterinary MH - Male MH - Pancreatic Insufficiency/blood/veterinary MH - Support, Non-U.S. Gov't RN - 0 (Caseins) RN - 9007-41-4 (C-Reactive Protein) PT - JOURNAL ARTICLE DA - 870811 DP - 1987 Jun IS - 0002-9645 TA - Am J Vet Res PG - 919-21 SB - M CY - UNITED STATES IP - 6 VI - 48 JC - 40C AA - Author EM - 8710 AB - Serum concentrations of C-reactive protein (CRP) in dogs with various diseases or undergoing various procedures were measured by specific immunoassay. In 20 healthy dogs from various sources, values were all less than 5 mg/L, but in 22 healthy dogs from a single source, values ranged from less than 5 mg/L in 14 dogs and from 8 to 67 mg/L in 8 dogs. Increased concentrations of serum CRP were attained 24 hours after injection of casein (n = 9; median 188 mg/L), ovariohysterectomy (n = 11; median, 144 mg/L), or elective, nonacute orthopedic surgery (n = 10; median, 83 mg/L). After inoculation of Leptospira interrogans serovar canicola (n = 5), the behavior of serum CRP as an acute-phase reactant provided a sensitive and precise objective reflection of in vivo response. The CRP concentration in random single-serum samples from 73 dogs with other inflammatory and noninflammatory disorders ranged from normal (less than 5 mg/L) to 246 mg/L and generally correlated with the extent and activity of disease. PMID- 3605808 CU - 92 SO - Am J Vet Res 1987 Jun;48(6):919-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 88023021 AU - de Brito T AU - Morais CF AU - Yasuda PH AU - Lancellotti CP AU - Hoshino-Shimizu S AU - Yamashiro E AU - Ferreira Alves VA TI - Cardiovascular involvement in human and experimental leptospirosis: pathologic findings and immunohistochemical detection of leptospiral antigen. LA - Eng MH - Adult MH - Aged MH - Animal MH - Antigens, Bacterial/*analysis MH - Female MH - Guinea Pigs MH - Histocytochemistry MH - Human MH - Immunoenzyme Techniques MH - Leptospirosis/immunology/*pathology MH - Male MH - Middle Age MH - Myocardial Diseases/immunology/*pathology MH - Myocarditis/pathology MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 871119 DP - 1987 Jun IS - 0003-4983 TA - Ann Trop Med Parasitol PG - 207-14 SB - M CY - ENGLAND IP - 3 VI - 81 JC - 68E AA - Author EM - 8801 AB - Twenty hearts from patients dying of leptospirosis were studied. Interstitial myocarditis was found in 50% of the cases, and a significant statistical correlation was observed between myocarditis and the inflammatory involvement of the conduction tissue. Acute coronary arteritis, affecting the main branches of the coronary arteries, was observed in 70% of the cases, and this finding also correlates significantly with interstitial myocarditis. Aortitis was found in 57.8% of the cases. When serum against L. interrogans serovar icterohaemorrhagiae was used, focal IP antigen deposits were observed in the coronary arteries and in the aorta. Experimental data from 12 guinea-pigs inoculated with L. interrogans serovar icterohaemorrhagiae showed a focal myocarditis involving mainly the subendocardial and pericoronary heart tissue, with IP antigen deposits in the same sites. Leptospirosis might be visualized as a generalized illness resembling other infectious vasculitides. The heart and main vessels are involved during the septicaemic phase of the disease, and bacterial migration, toxin(s), enzymes and/or antigenic products liberated by bacterial lysis might account for the increased endothelial permeability with antigen deposits and inflammation. AD - Faculty of Medicine, Department of Pathology, University of Sao Paulo, Brazil. PMID- 3310933 CU - 91 SO - Ann Trop Med Parasitol 1987 Jun;81(3):207-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 88031512 AU - Ratnam S AU - Venugopal K AU - Kathiravan V TI - Evidence of leptospiral infections in human samples in Madras city. LA - Eng MH - Antibodies, Bacterial/*analysis MH - Bacteriuria MH - Human MH - India MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology MH - Seasons MH - Septicemia RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 871215 DP - 1987 May IS - 0019-5340 TA - Indian J Med Res PG - 516-8 CY - INDIA VI - 85 JC - GJF EM - 8802 PMID- 3666852 CU - 91 SO - Indian J Med Res 1987 May;85:516-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 88009934 AU - Ono E AU - Takase H AU - Naiki M AU - Yanagawa R TI - Purification, characterization and serological properties of a glycolipid antigen reactive with a serovar-specific monoclonal antibody against Leptospira interrogans serovar canicola. LA - Eng MH - *Antibodies, Monoclonal MH - *Antigens, Bacterial MH - Chromatography, Gas MH - Chromatography, Thin Layer MH - Glycolipids/*immunology MH - Leptospira interrogans/*immunology MH - Spectrophotometry, Infrared MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Glycolipids) PT - JOURNAL ARTICLE DA - 871120 DP - 1987 May IS - 0022-1287 TA - J Gen Microbiol PG - 1329-36 SB - M CY - ENGLAND VI - 133 ( Pt 5) JC - I87 AA - Author EM - 8801 AB - A glycolipid antigen possessing a serovar-specific antigenic determinant of Leptospira interrogans serovar canicola was purified from a chloroform/methanol extract of the organism. The purification procedures included silicic acid column chromatography and preparative thin-layer chromatography (TLC). Antigenic activity was detected by a TLC-enzyme immunostaining technique using monoclonal antibody CT3, which specifically agglutinates serovar canicola and only weakly serovar sumneri but no other serovars of Leptospira. The purified glycolipid reacted with CT3 antibody, indicating that the glycolipid possessed a serovar-specific antigenic determinant. Infrared spectrum and proton nuclear magnetic resonance analyses showed that the glycolipid contained sugar and lipid moieties, which possessed amide linkages and an acetyl group. Gas-liquid chromatography-mass spectrometry analysis showed that the glycolipid contained two unknown sugars, one of which (unknown sugar II) appeared to be associated with the antigenic determinant specific for canicola. The serovar-specific antigenic determinant was destroyed by mild alkali treatment of the glycolipid. These findings suggested that the antigenic determinant was an alkali-labile moiety which may be related to the unknown sugar II. AD - Department of Hygiene and Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. PMID- 3655741 CU - 92 SO - J Gen Microbiol 1987 May;133 ( Pt 5):1329-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 87223005 AU - Myers DM TI - Serodiagnosis of human leptospirosis by counterimmunoelectrophoresis. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial/immunology MH - Comparative Study MH - Counterimmunoelectrophoresis MH - Human MH - Leptospira interrogans/*immunology MH - Rabbits MH - Weil's Disease/*diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 870717 DP - 1987 May IS - 0095-1137 TA - J Clin Microbiol PG - 897-9 SB - M CY - UNITED STATES IP - 5 VI - 25 JC - HSH AA - Author EM - 8709 AB - The counterimmunoelectrophoresis (CIE) technique employing a soluble extract antigen was found useful in screening human sera for antileptospiral antibodies to multiple leptospiral serovars. The CIE test results with sera from patients with suspected cases of leptospirosis and sera from a control group compared favorably (97.9%) with those obtained by the microscopic agglutination test using a battery of live leptospiral antigens. CIE is easy to perform, is highly sensitive, uses an antigen which is very stable at room temperature, and permits the screening of many sera in a short period of time. The CIE technique appears to be ideally suited to a small laboratory where facilities may be too limited for examining sera by the microscopic agglutination test. PMID- 3584424 CU - 91 SO - J Clin Microbiol 1987 May;25(5):897-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 88019728 AU - Chapman AJ AU - Adler B AU - Faine S TI - Genus-specific antigens in Leptospira revealed by immunoblotting. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Chromatography, Gel MH - Chromatography, High Pressure Liquid MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel MH - Female MH - Immunoassay MH - Immunoenzyme Techniques MH - Leptospira/*immunology MH - Leptospira interrogans/*immunology MH - Rabbits MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 871119 DP - 1987 May IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 279-93 SB - M CY - GERMANY, WEST IP - 3-4 VI - 264 JC - Y55 AA - Author EM - 8801 AB - Immunoblotting of leptospiral sonicates with heterologous rabbit antisera revealed a distinct cross-reactive pattern which differed with respect to the pathogenic and non-pathogenic leptospiral serovars, and that all serovars tested from Leptospira interrogans, L. biflexa and L. illini contained a common 35 kilodalton (Kd) band. A leptospiral genus- specific antigen preparation produced by ethanol fractionation of L. biflexa serovar patoc reacted by enzyme immunoassay (EIA) with all heterologous serovars tested. Further purification using Sephacryl S- 300 gel filtration revealed one major cross-reactive peak and several homologous peaks detectable by EIA. Gel electrophoresis of this peak revealed 3 major protein bands of 35, 34 and 29 Kd by Coomassie blue staining. This peak was further fractionated by high pressure liquid chromatography (HPLC), yielding 7 fractions, one of which cross- reacted. Rabbit antisera to this S-300/HPLC fraction reacted with all serovars tested. Immunoblotting revealed 2 distinct groups of cross- reactive antigens, a 33-35 Kd group that was proteinase K sensitive but not reduced by periodate oxidation, and a 14.4-26.5 Kd group whose activity was reduced by periodate but not proteinase K, indicating the presence of both protein and carbohydrate genus antigens. Immunoblotting L. interrogans serovar pomona flagella with S-300/HPLC antiserum suggested that the 35 Kd band found in all serovars tested was a flagellar component. AD - Department of Microbiology, Monash University, Clayton, Melbourne, Australia. PMID- 3310456 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 May;264(3-4):279-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 87226085 AU - De Koning J AU - Bosma RB AU - Hoogkamp-Korstanje JA TI - Demonstration of spirochaetes in patients with Lyme disease with a modified silver stain. LA - Eng MH - Animal MH - Borrelia/isolation & purification MH - Hamsters MH - Human MH - Leptospira/isolation & purification MH - Lyme Disease/*microbiology MH - Silver/*diagnostic use MH - Spirochaetales/*isolation & purification MH - Staining MH - Treponema pallidum/isolation & purification RN - 7440-22-4 (Silver) PT - JOURNAL ARTICLE DA - 870629 DP - 1987 May IS - 0022-2615 TA - J Med Microbiol PG - 261-7 SB - M CY - ENGLAND IP - 3 VI - 23 JC - J2N AA - Author EM - 8709 AB - Spirochaetes were demonstrated in material from patients with Lyme disease by short-time high-concentrate silver impregnation after treatment with amylase. Removal of mucoid material was essential to visualise Borrelia burgdorferi. Lyme spirochaetes were demonstrated in material from 23 patients with Lyme disease--erythema chronicum migrans (ECM) 10, lymphadenosis benigna cutis (LABC) 7, arthritis 4 and Bannwarth's syndrome 2. Spirochaetes were localised in the subepidermal zone, peri- and intravascularly, and in collagen fibres in ECM and LABC, and beneath the synovial lining cells in arthritis, producing marked vascular changes with fibrosis and synovial hyperplasia. Spirochaetes were also demonstrated in CSF from a patient with Bannwarth's syndrome. PMID- 2438410 CU - 95 SO - J Med Microbiol 1987 May;23(3):261-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 87172395 AU - Desmarchelier PM TI - Human leptospirosis in New South Wales, 1975-1985. LA - Eng MH - Australia MH - Dairying MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology/etiology MH - Occupational Diseases/epidemiology PT - JOURNAL ARTICLE DA - 870514 DP - 1987 Apr 6 IS - 0025-729X TA - Med J Aust PG - 353-7 SB - M SB - X CY - AUSTRALIA IP - 7 VI - 146 JC - M26 AA - Author EM - 8707 AB - From July 1975 to June 1985, 14,630 sera from patients in New South Wales were tested for serological evidence of leptospirosis. Among these, 361 sera contained evidence of past infections and 150 of these 361 specimens had evidence of recent or current infections. Serologically-diagnosed cases of leptospirosis were distributed mainly in the central and eastern parts of the State. Pomona, hardjo and icterohaemorrhagiae were the most common serovars to be detected; male abattoir workers and farmers were the most common occupational groups that were infected. An increase in seropositive cases occurred from 1981, largely due to hardjo and to a lesser extent pomona infections among farmers. Clinical histories indicated that most cases presented as pyrexias of unknown origin or as febrile illnesses; however, four patients were reported to have presented with renal failure; three patients were reported to have presented with meningitis; and 10 patients were jaundiced at presentation. RO - M:MWS PMID- 3561288 LR - 900119 CU - 88 SO - Med J Aust 1987 Apr 6;146(7):353-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 88009912 AU - Terpstra WJ AU - Schoone GJ AU - Ligthart GS AU - ter Schegget J TI - Detection of Leptospira interrogans in clinical specimens by in situ hybridization using biotin-labelled DNA probes. LA - Eng MH - Animal MH - Cattle MH - DNA, Bacterial/*classification MH - Hamsters MH - Human MH - Leptospira interrogans/*classification MH - Liver/microbiology MH - Mesocricetus MH - *Nucleic Acid Hybridization MH - Serotyping RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 871120 DP - 1987 Apr IS - 0022-1287 TA - J Gen Microbiol PG - 911-4 SB - M CY - ENGLAND VI - 133 ( Pt 4) JC - I87 AA - Author EM - 8801 AB - In situ DNA hybridization using biotin-labelled leptospiral DNA was performed on clinical specimens to investigate its usefulness as a technique for the identification of Leptospira interrogans. The applicability of this test in blood, urine and liver smears was demonstrated. In situ DNA hybridization can be completed in only 4 h and it combines the advantage of visualization of the leptospiral morphology with the specificity of the hybridization reaction. No cross- hybridization was observed with other bacteria. This study shows that hybridization in situ can be simple to perform and may contribute to a rapid diagnosis. AD - Royal Tropical Institute, Department of Tropical Hygiene, Amsterdam, The Netherlands. PMID- 3655736 CU - 91 SO - J Gen Microbiol 1987 Apr;133 ( Pt 4):911-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 87321961 AU - Neill SD AU - Reid RL AU - Weatherup ST AU - Ellis WA TI - The use of aminopeptidase substrate specificity profiles to identify leptospires. LA - Eng MH - Aminopeptidases/*metabolism MH - Animal MH - Base Composition MH - Comparative Study MH - Computers MH - DNA, Bacterial/analysis MH - Human MH - Leptospira/classification/*enzymology/genetics/isolation & purification MH - Substrate Specificity RN - EC 3.4.11. (Aminopeptidases) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 871007 DP - 1987 Apr IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 137-44 SB - M CY - GERMANY, WEST IP - 1-2 VI - 264 JC - Y55 AA - Author EM - 8712 AB - Thirty reference Leptospira strains and twelve leptospire-like cultures were examined for aminopeptidase activity using twenty-two aminoacyl- beta-naphthylamide substrates. Aminopeptidase activity was demonstrated in extracts of each of the cultures and their substrate specificity profiles compared using several computer analysis procedures. The specificity profiles were consistent for each of the strains examined. Leptospira were readily differentiated from non Leptospira strains. This was supported by DNA base ratios calculated for the strains. Of the non Leptospira strains, seven appeared similar to the "L. illini" cultured included. Two of these strains, which included the strain "L. parva" sp. nov., formed a subgroup of this "L. illini" group. Substrate specificity profiles for the L. interrogans and L. biflexa strains examined were also different from each other. PMID- 3630469 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 Apr;264(1-2):137-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 87320634 AU - Everard CO AU - Fraser-Chanpong GM AU - Everard JD TI - The incidence of severe leptospirosis in Trinidad. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Aged, 80 and over MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - Child MH - Female MH - Human MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Sex Factors MH - Support, Non-U.S. Gov't MH - Trinidad and Tobago MH - Weil's Disease/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 871016 DP - 1987 Apr IS - 0041-3232 TA - Trop Geogr Med PG - 126-32 SB - M CY - NETHERLANDS IP - 2 VI - 39 JC - WGJ AA - Author EM - 8712 AB - Between February 1977 and September 1982, sera from febrile patients from all areas of Trinidad were examined for leptospiral agglutinins; 158 of 1714 patients (9%) were confirmed as current cases of leptospirosis (annual average 26 or 2.6 per 100,000 population). Of the remaining 1556 patients only 711 provided paired sera; 167 of these (23%) showed evidence of previous leptospiral infection. Of the 845 single samples, 125 were positive. The true incidence of the disease is probably much higher than reported here. Males comprised 74% of the current cases; their highest rate of infection was in the 30-39 year age group, the incidence in late teenage approaching this rate. For females, incidence increased with age up to late middle-age. The presumptive infecting serogroups most commonly recorded among the 158 current cases were Icterohaemorrhagiae (37%), Canicola (16%) and Autumnalis (11%). 13 of the cases died (case fatality rate, 8.2%). PMID- 3629704 CU - 91 SO - Trop Geogr Med 1987 Apr;39(2):126-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 87255679 AU - Pupkevich-Diamant IaS AU - Polotskii IuE AU - Semenovich VN AU - Popova EM AU - Stoianova NA TI - [Clinical aspects and pathomorphology of leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Aged MH - English Abstract MH - Female MH - Hepatitis/etiology/pathology MH - Human MH - Leptospira/classification MH - Leptospirosis/*diagnosis MH - Male MH - Middle Age MH - Nephritis/etiology/pathology PT - JOURNAL ARTICLE DA - 870817 DP - 1987 Apr IS - 0023-2149 TA - Klin Med (Mosk) PG - 102-8 CY - USSR IP - 4 VI - 65 JC - KW2 EM - 8710 PMID- 3599835 TT - Klinika i patomorfologiia leptospiroza. EA - A SO - Klin Med (Mosk) 1987 Apr;65(4):102-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 87179384 AU - Alleyne GA TI - Renal disease in Africa and the Caribbean: an overview. LA - Eng MH - Adolescence MH - Adult MH - Africa MH - Anemia, Sickle Cell/complications MH - Child MH - Child, Preschool MH - Human MH - Hypertension/complications MH - Infant MH - Kidney Diseases/*ethnology/epidemiology/etiology MH - Kidney Failure, Chronic/etiology MH - Leptospirosis/complications MH - Malaria/complications/epidemiology MH - *Negroid Race MH - Streptococcal Infections/complications MH - West Indies PT - JOURNAL ARTICLE DA - 870512 DP - 1987 Apr IS - 0041-1345 TA - Transplant Proc PG - 9-14 SB - M SB - X CY - UNITED STATES IP - 2 Suppl 2 VI - 19 JC - WE9 EM - 8707 PMID- 3564141 CU - 88 SO - Transplant Proc 1987 Apr;19(2 Suppl 2):9-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 87206853 AU - Holzhauer C TI - [Interpretation of results of serologic analyses in large animal practices] LA - Dut MH - Animal MH - Antigens/*analysis MH - Bacterial Infections/immunology/veterinary MH - Bovine Virus Diarrhea-Mucosal Disease/immunology MH - Cattle MH - Cattle Diseases/*immunology MH - English Abstract MH - Female MH - Immunologic Techniques/veterinary MH - Infectious Bovine Rhinotracheitis/immunology MH - Milk/immunology MH - Respiratory Syncytial Viruses/immunology MH - Serodiagnosis/*veterinary RN - 0 (Antigens) PT - JOURNAL ARTICLE DA - 870601 DP - 1987 Apr 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 390-5 SB - M CY - NETHERLANDS IP - 7 VI - 112 JC - VRY AA - Author EM - 8708 AB - The backgrounds to and possibilities of serological studies for the purpose of establishing are reviewed, all this with regard to bovine disease. The serology of the virus infections infectious bovine rhinotracheitis (IBR), bovine viral diarrhoea (BVD), para-influenza virus 3 infection (PI3), bovine respiratory syncytial virus (BRS) and Chlamydia is discussed in greater detail. Likewise, the interpretation of serological findings in cases of brucellosis, leptospirosis and Johne's disease is dealt with. In addition, attention is paid to the results of serological testing in cases of lung-worm disease and fascioliasis. PMID- 3554606 CU - 91 TT - De interpretatie van serologische onderzoekresultaten in de grote huisdierenpraktijk. EA - A SO - Tijdschr Diergeneeskd 1987 Apr 1;112(7):390-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 87162221 AU - Palmer MF AU - Waitkins SA AU - Fitzgeorge RB AU - Baskerville A TI - Experimental infection of monkeys with Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Cercopithecus aethiops MH - Female MH - Fluorescent Antibody Technique MH - Leptospira interrogans/*classification/isolation & purification MH - Male MH - Serotyping MH - Skin/injuries MH - Weil's Disease/*microbiology/pathology PT - JOURNAL ARTICLE DA - 870515 DP - 1987 Apr IS - 0950-2688 TA - Epidemiol Infect PG - 191-7 SB - M CY - ENGLAND IP - 2 VI - 98 JC - EPI AA - Author EM - 8707 AB - Grivet monkeys experimentally infected with two different strains of Leptospira interrogans serovar hardjo showed no signs of severe clinical disease. There were no significant macroscopic lesions in any of the tissues examined, but the organisms were demonstrated in various tissues by immunofluorescent technique and were isolated from the blood and urine of two monkeys and the kidney of one. Abraded skin was shown to be a viable route of infection in non-human primates. PMID- 3549342 CU - 90 SO - Epidemiol Infect 1987 Apr;98(2):191-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 87272964 AU - Prescott JF AU - Miller RB AU - Nicholson VM TI - Isolation of Leptospira hardjo from kidneys of Ontario cattle at slaughter. LA - Eng MH - Abattoirs MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*epidemiology/microbiology MH - Fluorescent Antibody Technique MH - Kidney/*microbiology MH - Leptospira/immunology/*isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Ontario MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870923 DP - 1987 Apr IS - 0830-9000 TA - Can J Vet Res PG - 229-31 SB - M CY - CANADA IP - 2 VI - 51 JC - CKL AA - Author EM - 8711 AB - Kidneys from 117 cattle from 110 Ontario farms were examined at slaughter for leptospires. Leptospira hardjo (hardjo-bovis A) was isolated from 11 kidneys and L. kennewicki from one. The isolations were all made (12/89, 13.5%) from beef cattle from feedlots, no isolates being obtained from dairy or beef cattle from extensive farms (0/28). Isolations were only made from cattle with antibody titers (greater than or equal to 20) against the serovars recovered. Isolation was more sensitive than immunofluorescence in identifying leptospira, particularly in animals with low antibody titers against L. hardjo. Leptospira were isolated from two kidneys with multiple gross lesions of focal nephritis, but there was no correlation between the presence of scanty kidney lesions and isolations of leptospira. Leptospira hardjo infection appears to be common in Ontario feedlot cattle. PMID- 3300922 CU - 91 SO - Can J Vet Res 1987 Apr;51(2):229-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 87321981 AU - Bornstein N AU - Fleurette J AU - Bebear C AU - Chabanon G TI - Bacteriological and serological diagnosis of community-acquired acute pneumonia, specially Legionnaire's disease. Multicentric prospective study of 274 hospitalized patients. LA - Eng MH - Acute Disease MH - Adult MH - Aged MH - Antibodies, Bacterial/analysis MH - Female MH - Fluorescent Antibody Technique MH - Human MH - Legionella/immunology/isolation & purification MH - Legionnaires' Disease/*diagnosis MH - Male MH - Middle Age MH - Mycoplasma pneumoniae/immunology/isolation & purification MH - Pneumonia/*diagnosis/etiology MH - Pneumonia, Lobar/diagnosis MH - Prospective Studies MH - Streptococcus pneumoniae/immunology/isolation & purification RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 871007 DP - 1987 Apr IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 93-101 SB - M CY - GERMANY, WEST IP - 1-2 VI - 264 JC - Y55 AA - Author EM - 8712 AB - In 1982 and 1983 a prospective study was carried out involving 274 adult patients hospitalized with community-acquired acute pneumonia. The results of the bacteriological and serological diagnoses are presented here. Conventional and standardized bacteriological methods were used. All the serodiagnoses of LD were carried out with the 13 antigens produced by the "Centre National de Reference" (L. pneumophila 1, 2, 3, 4, 5, 6; L. micdadei; L. bozemanii, L. dumoffii, L. jordanis; L. gormanii; L. longbeachae 1 and 2). Standardized criteria were used for the interpretation of results. Conventional methods were used for the other serodiagnoses. Because the laboratory results had been interpreted very rigorously, an etiological diagnosis was established only in 51% of pneumonia cases. Other reasons, such as the frequent prescription of antibiotics prior to hospitalization, may explain why no aetiology could be determined in 49% of cases. The microbial agents responsible were: S. pneumoniae, Legionella and M. pneumoniae in 62% of cases; H. influenzae, K. pneumoniae, Chlamydia and S. aureus in 21.6%; and viruses in 8.6%. 29 (10%) of the 274 pneumonia cases were caused by Legionella, being second to S. pneumoniae. The preponderance of L. pneumophila was striking (22 cases), 3 Legionella strains were isolated (L. pneumophila serogroup 1:2 strains, serogroup 6:1 strain). Three associated or successive infections were observed (influenza, Leptospirosis, Coxiella infection). As regards the other bacteria, implication of the strain isolated was based on its multiple occurrence in several samples.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 3115004 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 Apr;264(1-2):93-101 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 87226525 AU - Davidson WR AU - Blue JL AU - Flynn LB AU - Shea SM AU - Marchinton RL AU - Lewis JA TI - Parasites, diseases and health status of sympatric populations of sambar deer and white-tailed deer in Florida. LA - Eng MH - Animal MH - Antibodies, Viral/analysis MH - Bluetongue/epidemiology MH - Bluetongue Virus/immunology MH - Comparative Study MH - *Deer MH - Female MH - Florida MH - Hantavirus/immunology MH - Health Status MH - Hemorrhagic Fevers, Viral/epidemiology/veterinary MH - Male MH - Nutritional Status MH - Parasitic Diseases/epidemiology/*veterinary MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Virus Diseases/epidemiology/*veterinary RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 870706 DP - 1987 Apr IS - 0090-3558 TA - J Wildl Dis PG - 267-72 SB - M CY - UNITED STATES IP - 2 VI - 23 JC - KEM AA - Author EM - 8709 AB - From December 1983 to December 1984 a study on parasites, diseases and health status was conducted on sympatric populations of sambar deer (Cervus unicolor) and white-tailed deer (Odocoileus virginianus) from St. Vincent Island, Franklin County, Florida. Ten sambar and six white- tailed deer were examined. White-tailed deer had antibodies to epizootic hemorrhagic disease virus and bluetongue virus. Serologic tests for antibodies to the etiologic agents of bovine virus diarrhea, infectious bovine rhinotracheitis, vesicular stomatitis, parainfluenza 3, brucellosis, and leptospirosis were negative in both species of deer. White-tailed deer harbored 19 species of parasites; all were typical of the parasite fauna of this species in coastal regions of the southeastern United States. Sambar deer harbored 13 species of parasites, which apparently were derived largely from white-tailed deer. The only exception was Dermacentor variabilis which occurs frequently on wild swine on the island. The general health status of sambar deer appeared to be better than that of white-tailed deer. This was hypothesized to result from the sambar deer's utilization of food resources unavailable or unacceptable to white-tailed deer and to the absence and/or lower frequency of certain pathogens in sambar deer. PMID- 3035242 CU - 93 SO - J Wildl Dis 1987 Apr;23(2):267-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 87266278 AU - Pupkevich-Diamant IaS AU - Nisnevich EB AU - Tormozova NM AU - Ryndich AA AU - Vasilets VV TI - [Etiological structure and clinical epidemiological characteristics of Leptospira infection in Rostov Province based on data from therapeutic institutions from 1960 to 1983] LA - Rus MH - Age Factors MH - Comparative Study MH - Disease Reservoirs MH - Ecology MH - English Abstract MH - Human MH - Leptospirosis/epidemiology/*etiology MH - Russia MH - Socioeconomic Factors MH - Weil's Disease/epidemiology/etiology PT - JOURNAL ARTICLE DA - 870810 DP - 1987 Apr IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 40-4 SB - M CY - USSR IP - 4 JC - Y9O AA - Author EM - 8710 AB - Changes in communal conditions, in economy, as well as in ecology and fauna, which took place in Rostov Province during the last decade (1973- 1983) determined shifts in the etiological structure of Leptospira infection and in its course. The study revealed an increase in morbidity caused by L. icterohaemorrhagiae (up to 61%) and L. hebdomadis (up to 22%) with a simultaneous decrease in the isolation rate of L. grippotyphosa and L. pomona (up to 2-3%). In most cases (77%) the diseases caused by leptospires of different serogroups were found to take an icteric course accompanied by the development of hepatorenal insufficiency (46%). The similarity of clinical manifestations in different etiological forms of Leptospira infection was determined by common pathogenetic and pathophysiological features characteristic of the development of the leptospiral infectious process. PMID- 2955616 CU - 92 TT - Etiologicheskaia struktura i kliniko-epidemiologicheskaia kharakteri stika leptospiroznoi infektsii v Rostovskoi oblasti po materialam nekotorykh lechebnykh uchrezhdenii za 1960--1983 gg. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1987 Apr;(4):40-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 87306496 AU - Mu GY AU - Lu Y AU - Zhang HL AU - Cao ZL AU - Dai BM AU - Wang XX AU - Cheng SQ AU - Liu XM AU - Li CL TI - [A study on the therapy of leptospirosis with gentamycin] LA - Chi MH - Adolescence MH - Adult MH - Child MH - Comparative Study MH - English Abstract MH - Female MH - Gentamicins/pharmacology/*therapeutic use MH - Human MH - Leptospira interrogans/drug effects MH - Male MH - Middle Age MH - Penicillin G/therapeutic use MH - Penicillin Resistance MH - Weil's Disease/*drug therapy RN - 0 (Gentamicins) RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 871020 DP - 1987 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 82-5 CY - CHINA IP - 1 VI - 18 JC - GEB EM - 8712 PMID- 3650196 CU - 92 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1987 Mar;18(1):82-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 87193603 AU - Maffei C AU - Di Stanislao F TI - Recreational infections [letter] LA - Eng MH - Animal MH - Animals, Domestic MH - Animals, Wild MH - Disease Reservoirs MH - Human MH - Leptospirosis/*etiology MH - *Recreation PT - LETTER DA - 870605 DP - 1987 Mar IS - 0195-9417 TA - Infect Control PG - 90 SB - M SB - N CY - UNITED STATES IP - 3 VI - 8 JC - GTM EM - 8708 PMID- 3646183 CU - 91 SO - Infect Control 1987 Mar;8(3):90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 87321355 AU - Zhang FZ AU - Long PR AU - Meng PY AU - Wang JJ TI - [Identification of Leptospira kunming of the Pomona serogroup] LA - Chi MH - China MH - English Abstract MH - Leptospira interrogans/*classification MH - Nomenclature MH - Serotyping PT - JOURNAL ARTICLE DA - 871007 DP - 1987 Mar IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 88-91 CY - CHINA IP - 1 VI - 27 JC - XNA EM - 8712 PMID- 3630141 EA - A SO - Wei Sheng Wu Hsueh Pao 1987 Mar;27(1):88-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 87306477 AU - Xu LL AU - Wang BY AU - Dai BM AU - Wang BZ TI - [Studies of the immunological protection of a ribosomal extract isolated from Leptospira] LA - Chi MH - Animal MH - English Abstract MH - Guinea Pigs MH - Leptospira interrogans/analysis/*immunology MH - Ribosomal Proteins/*immunology MH - RNA, Ribosomal/*immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/*prevention & control RN - 0 (Ribosomal Proteins) RN - 0 (RNA, Ribosomal) PT - JOURNAL ARTICLE DA - 871020 DP - 1987 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 14-7 CY - CHINA IP - 1 VI - 18 JC - GEB EM - 8712 PMID- 3623516 CU - 92 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1987 Mar;18(1):14-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 87237111 AU - Schonberg A AU - Staak C AU - Kampe U TI - [Leptospirosis in West Germany. Results of a research program on leptospirosis in animals in the year 1984] LA - Ger MH - Animal MH - *Animals, Domestic MH - Cattle MH - Dogs MH - English Abstract MH - Germany, West MH - Goats MH - Horses MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Sheep MH - Swine PT - JOURNAL ARTICLE DA - 870713 DP - 1987 Mar IS - 0514-7166 TA - Zentralbl Veterinarmed [B] PG - 98-108 CY - GERMANY, WEST IP - 2 VI - 34 JC - Y72 EM - 8709 PMID- 3591115 CU - 88 TT - Leptospirose in der Bundesrepublik Deutschland. Ergebnisse eines Untersuchungsprogrammes auf Leptospirose bei Tieren im Jahre 1984. EA - A SO - Zentralbl Veterinarmed [B] 1987 Mar;34(2):98-108 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 87230151 AU - Hunter P AU - van der Vyver FH AU - Selmer-Olsen A AU - Henton MM AU - Herr S AU - de Lange JF TI - Leptospirosis as a cause of "white spot" kidneys in South African pig abattoirs. LA - Eng MH - Abattoirs MH - Animal MH - Kidney/microbiology/*pathology MH - Leptospira/isolation & purification MH - Leptospirosis/pathology/*veterinary MH - Swine MH - Swine Diseases/*pathology PT - JOURNAL ARTICLE DA - 870702 DP - 1987 Mar IS - 0030-2465 TA - Onderstepoort J Vet Res PG - 59-62 SB - M CY - SOUTH AFRICA IP - 1 VI - 54 JC - OI6 AA - Author EM - 8709 AB - The incidence of isolation of Leptospira sp. from the kidneys of slaughter pigs with "white-spot" macroscopic lesions was determined. Histology and general bacteriology were performed. Leptospira pomona was isolated from 19/21 kidneys showing macroscopic lymphocytic lesions. PMID- 3587928 SO - Onderstepoort J Vet Res 1987 Mar;54(1):59-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [55 medline neighbors] UI - 87209704 AU - Miller CD AU - Songer JR AU - Sullivan JF TI - A twenty-five year review of laboratory-acquired human infections at the National Animal Disease Center. LA - Eng MH - Animal MH - Brucellosis/transmission MH - Human MH - Laboratory Infection/*transmission MH - Leptospirosis/transmission/veterinary MH - Mycobacterium Infections/transmission/veterinary MH - Syringes/veterinary MH - Zoonoses/*transmission PT - JOURNAL ARTICLE DA - 870526 DP - 1987 Mar IS - 0002-8894 TA - Am Ind Hyg Assoc J PG - 271-5 SB - M CY - UNITED STATES IP - 3 VI - 48 JC - 3CI AA - Author EM - 8708 AB - The National Animal Disease Center's experience with personnel exposure or infection with pathogenic agents is summarized. A total of 128 laboratory-associated exposures to infectious disease agents were reported. Of these exposures, 103 resulted from known accidents. The other 25 were identified only after the development of clinical or serological manifestations of infection. Thirty-four cases of laboratory-acquired infections were reviewed. Class 3 organisms-- Chlamydia sp., Brucella sp. and Mycobacterium sp.--were responsible for 76% of the infections encountered, with Brucella sp. incriminated most frequently. The most commonly reported cause of exposure was associated with hypodermic syringe use. Unknown routes of exposure, presumed to be aerosol related, were the overwhelming explanation involved in the laboratory-associated infections. PMID- 3578038 SO - Am Ind Hyg Assoc J 1987 Mar;48(3):271-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 87190295 AU - Davidson MG AU - Nasisse MP AU - Roberts SM TI - Immunodiagnosis of leptospiral uveitis in two horses. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Case Report MH - Horse Diseases/*diagnosis/immunology MH - Horses MH - Immunologic Tests/veterinary MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/immunology/*veterinary MH - Male MH - Uveitis/diagnosis/immunology/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870601 DP - 1987 Mar IS - 0425-1644 TA - Equine Vet J PG - 155-7 SB - M CY - ENGLAND IP - 2 VI - 19 JC - EJ9 EM - 8708 PMID- 3569201 CU - 91 SO - Equine Vet J 1987 Mar;19(2):155-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 87190287 AU - Matthews AG AU - Waitkins SA AU - Palmer MF TI - Serological study of leptospiral infections and endogenous uveitis among horses and ponies in the United Kingdom. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Great Britain MH - Horse Diseases/*immunology/microbiology MH - Horses MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Support, Non-U.S. Gov't MH - Uveitis, Anterior/immunology/microbiology/*veterinary RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 870601 DP - 1987 Mar IS - 0425-1644 TA - Equine Vet J PG - 125-8 SB - M CY - ENGLAND IP - 2 VI - 19 JC - EJ9 AA - Author EM - 8708 AB - The prevalence of antibody titres to a range of 20 leptospira antigens in the serum of horses and ponies with no ophthalmic abnormalities and with ophthalmoscopic evidence of endogenous uveal inflammatory disease was determined using a microscopic agglutination technique. Titres against leptospira antigens were observed in 13 out of 138 (9.1 per cent) animals with no ophthalmic abnormalities, and in three out of 27 (11.1 per cent) animals with anterior uveitis. Serovar sejroe was common to all seropositive animals with anterior uveitis. The results show that leptospira infection is not a major factor in the aetiology of equine anterior uveitis in the UK, but suggests that the organism may be associated with some cases of recurrent anterior uveitis. PMID- 3569193 CU - 91 SO - Equine Vet J 1987 Mar;19(2):125-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 87182564 AU - Gregoire N AU - Higgins R AU - Robinson Y TI - Isolation of leptospires from nephritic kidneys of beef cattle at slaughter. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Carrier State/epidemiology/veterinary MH - Cattle MH - *Cattle Diseases MH - Kidney/*microbiology/pathology MH - Leptospira interrogans/classification/immunology/*isolation & purification MH - Leptospirosis/complications/epidemiology/immunology/*veterinary MH - Male MH - Nephritis, Interstitial/complications/*veterinary MH - Serotyping RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870512 DP - 1987 Mar IS - 0002-9645 TA - Am J Vet Res PG - 370-1 SB - M CY - UNITED STATES IP - 3 VI - 48 JC - 40C AA - Author EM - 8707 AB - Of 955 beef cattle slaughtered at an abattoir in Quebec from May to August 1985, 122 (13%) had lesions of focal interstitial nephritis. Nephritic kidneys were collected for leptospiral culture, and matching blood samples were examined serologically. Leptospires were isolated from the kidneys of 35 (29%) cattle. Antibodies to Leptospira interrogans serovar hardjo were found in 29 (24%) cattle and to pomona in 13 (10%). PMID- 3565891 CU - 91 SO - Am J Vet Res 1987 Mar;48(3):370-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 87182584 AU - Dubey JP AU - Hughes HP AU - Lillehoj HS AU - Gamble HR AU - Munday BL TI - Placental transfer of specific antibodies during ovine congenital toxoplasmosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Formation MH - Female MH - Haemonchus/immunology MH - *Immunity, Maternally-Acquired MH - Leptospira interrogans/immunology MH - Placenta/*immunology/pathology MH - Pregnancy MH - Sarcocystis/immunology MH - Sheep MH - Sheep Diseases/congenital/*immunology/pathology MH - Toxoplasma/*immunology MH - Toxoplasmosis, Animal/*congenital/immunology/pathology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870512 DP - 1987 Mar IS - 0002-9645 TA - Am J Vet Res PG - 474-6 SB - M CY - UNITED STATES IP - 3 VI - 48 JC - 40C AA - Author EM - 8707 AB - The passage of non-Toxoplasma antibodies from dam to fetus through damaged placenta was studied in sheep inoculated with Toxoplasma gondii. Six ewes were inoculated with chicken globulins and Leptospira bacterins 2 months before oral inoculation with Toxoplasma gondii oocysts. Ewes were euthanatized between 42 and 62 days after T gondii inoculation. Antibody titers against chicken globulins, Leptospira spp, Haemonchus contortus, Sarcocystis spp, and T gondii were measured in the maternal and fetal sera. All ewes became infected with T gondii and had grossly visible necrotic foci in the placentas, and T gondii antibodies were found in the fetuses and the ewes. Appreciable amounts of antibodies to Haemonchus contortus, Sarcocystis sp, Leptospira spp, and chicken globulins did not cross the placental barrier. Seemingly, serologic examination of the fetus was reliable for the diagnosis of ovine congential toxoplasmosis. PMID- 3105371 CU - 91 SO - Am J Vet Res 1987 Mar;48(3):474-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 87155112 AU - Cornaert P AU - Masson P AU - Forzy G AU - Graux P AU - Camblin J AU - Dutoit A AU - Croccel L TI - [Infectious endocarditis caused by rare germs. Review of the literature apropos of 2 cases] LA - Fre MH - Adult MH - Case Report MH - Endocarditis, Bacterial/*microbiology MH - English Abstract MH - Female MH - Human MH - Leptospira interrogans MH - Male MH - Middle Age MH - *Pasteurella Infections MH - *Weil's Disease PT - JOURNAL ARTICLE DA - 870423 DP - 1987 Feb IS - 0003-3928 TA - Ann Cardiol Angeiol (Paris) PG - 87-93 SB - M CY - FRANCE IP - 2 VI - 36 JC - 502 AA - Author EM - 8706 AB - The authors report two new cases of endocarditis secondary to exceptionnally encountered germs: one to Pasteurella pneumotropica, the other ascribed to Leptospira ictero-haemorragiae, on serologic criteria. Concerning these two cases, they propose to take a census of rare germs, from a detailed study of the literature. Among more than 5,000 cases of endocarditis published after 1944, are considered as rare germs those causing a disease in less than one p. cent of the cases. This purely "mathematical" definition enable to include 45 germs. A synthesis of all the cases reported attempts to demonstrate a few particular traits of these endocardites secondary to rare germs. PMID- 3827160 TT - Les endocardites infectieuses a germes rares. Revue de la litterature a propos de deux observations. EA - A SO - Ann Cardiol Angeiol (Paris) 1987 Feb;36(2):87-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 87141115 AU - Farrelly HE AU - Adler B AU - Faine S TI - Opsonic monoclonal antibodies against lipopolysaccharide antigens of Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Antibodies, Bacterial/*immunology MH - Antibodies, Monoclonal/*immunology MH - Antibody Specificity MH - Leptospira interrogans/classification/*immunology MH - Lipopolysaccharides/*immunology MH - Macrophages/immunology MH - Mice MH - Opsonins/immunology MH - Phagocytosis MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Lipopolysaccharides) RN - 0 (Opsonins) PT - JOURNAL ARTICLE DA - 870401 DP - 1987 Feb IS - 0022-2615 TA - J Med Microbiol PG - 1-7 SB - M CY - ENGLAND IP - 1 VI - 23 JC - J2N AA - Author EM - 8706 AB - Six monoclonal antibodies produced from mice immunised with Leptospira interrogans serovar hardjo were directed against determinants in the leptospiral lipopolysaccharide, as indicated by immunodiffusion and enzyme immunoassay (EIA), and opsonised leptospires for phagocytosis by mouse macrophages. Their specificities were studied by agglutination and EIA. Five antibodies reacted with some, but not all, members of the Sejroe and Hebdomadis serogroups, and one antibody agglutinated exclusively members of the Sejroe group thus indentifying a serogroup- specific epitope. None of the six antibodies reacted with representative serovars of any other serogroup. PMID- 3820267 CU - 92 SO - J Med Microbiol 1987 Feb;23(1):1-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 87138231 AU - Pope V AU - Johnson RC TI - Effect of heat or chemical treatment on leptospiral antigens. LA - Eng MH - Antigens, Bacterial/analysis/*immunology MH - Formaldehyde/pharmacology MH - Heat MH - Leptospira interrogans/*immunology MH - Phenols/pharmacology MH - Thimerosal/pharmacology RN - 0 (Antigens, Bacterial) RN - 0 (Phenols) RN - 108-95-2 (phenol) RN - 50-00-0 (Formaldehyde) RN - 54-64-8 (Thimerosal) PT - JOURNAL ARTICLE DA - 870415 DP - 1987 Feb IS - 0095-1137 TA - J Clin Microbiol PG - 255-8 SB - M CY - UNITED STATES IP - 2 VI - 25 JC - HSH AA - Author EM - 8706 AB - The use of bacterins is one of the primary methods in the control of leptospirosis in domestic animals, especially cattle, swine, and dogs. Bacterins have been made using chemically treated or heat-inactivated organisms. Many of the initial studies indicated that the bacterins gave complete protection, whereas later reports found that some inactivation methods resulted in bacterins that protect against death but not against kidney infection and renal shedding. This raised the possibility that some of the antigens had been altered. To investigate this possibility, we heat or chemically treated Leptospira interrogans serovar icterohaemorrhagiae CF-1, L. interrogans serovar canicola Moulton, L. interrogans serovar grippotyphosa SC4397, L. interrogans serovar hardjo Hardjoprajitno, and L. interrogans serovar pomona MLS. Temperatures used to determine alterations in antigens were 50, 56, 80, 100, and 121 degrees C. The chemicals used were formaldehyde, phenol, and thimerosal. Analysis was done using Laemmli gels and Western blots. We found that heating at 50 or 56 degrees C had the smallest effect on antigens, whereas heating at 80 or 100 degrees C caused the appearance of high-molecular-weight bands on Western blots. Heating at 121 degrees C caused almost all the bands to disappear, in both the stained gel and the Western blot. Both phenol and Formalin treatment altered proteins, whereas thimerosal treatment appeared to have little effect compared with heating at 50 degrees C. PMID- 3818922 CU - 91 SO - J Clin Microbiol 1987 Feb;25(2):255-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 88031433 AU - Ratnam S AU - Sundararaj T AU - Subramanian S AU - Adinarayanan N TI - Experimental study with leptospires in bandicoot Bandicota bengalensis. LA - Eng MH - Animal MH - Antibody Formation MH - Kidney Cortex/*microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/immunology/*veterinary MH - Muridae/*microbiology PT - JOURNAL ARTICLE DA - 871202 DP - 1987 Feb IS - 0019-5189 TA - Indian J Exp Biol PG - 105-7 CY - INDIA IP - 2 VI - 25 JC - GIZ EM - 8802 RO - M:CNR PMID- 3666804 LR - 880205 SO - Indian J Exp Biol 1987 Feb;25(2):105-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 87237053 AU - Schulze TL AU - Bosler EM AU - Shisler JK AU - Ware IC AU - Lakat MF AU - Parkin WE TI - Prevalence of canine Lyme disease from an endemic area as determined by serosurvey. LA - Eng MH - Age Factors MH - Animal MH - Antibodies, Bacterial/*analysis MH - Borrelia/*immunology MH - Dog Diseases/*epidemiology/immunology MH - Dogs MH - Exertion MH - Lyme Disease/epidemiology/immunology/*veterinary MH - New Jersey MH - Travel RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870629 DP - 1987 Feb IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 427-34 SB - M CY - GERMANY, WEST IP - 3 VI - 263 JC - Y55 AA - Author EM - 8709 AB - From August 1984 through February 1985, 423 dogs from 43 municipalities in 7 New Jersey counties were evaluated for the presence of antibodies to the Lyme disease spirochete (Borrelia burgdorferi). Of these dogs, 34.7% with no apparent clinical symptoms were serologically reactive (IFA greater than or equal to 1:64); titers in this study ranged from non-reactive to 1:2048. Ninety percent of the dogs surveyed had a current vaccination status to Leptospira interrogans serovars canicola and icterohaemorhagiae. Dogs vaccinated to leptospirosis elicited homologous antibody titers of less than or equal to 1:16 and, therefore, did not interfere with interpretation of antibody levels to B. burgdorferi. Effects of age, degree of outdoor activity, travel history, and location of residence were evaluated. The use of serosurveys of dogs as a tool for Lyme disease surveillance is discussed. PMID- 3591094 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1987 Feb;263(3):427-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 87179736 AU - Parma AE AU - Fernandez AS AU - Santisteban CG AU - Bowden RA AU - Cerone SI TI - Tears and aqueous humor from horses inoculated with Leptospira contain antibodies which bind to cornea. LA - Eng MH - Animal MH - Antibodies, Bacterial/*isolation & purification MH - Antigens, Bacterial/administration & dosage MH - Aqueous Humor/immunology MH - Cornea/*immunology MH - Corneal Opacity/etiology/veterinary MH - Horse Diseases/etiology MH - Horses/*immunology MH - Leptospira interrogans/*immunology MH - Support, Non-U.S. Gov't MH - Tears/immunology MH - Weil's Disease/complications/veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 870515 DP - 1987 Feb IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 181-5 SB - M CY - NETHERLANDS IP - 2 VI - 14 JC - XCB AA - Author EM - 8707 AB - An antigenic relationship between Leptospira interrogans and equine cornea was previously described by us. An enzyme-linked immunosorbent assay was employed in the present work to investigate the existence of anti-leptospira and anti-cornea antibodies in tears, aqueous humor and serum from horses inoculated i.m. with those antigens. Ten days after a booster by the same route, antibodies that bind to microtiter plates, coated with an homogenate of either equine cornea or leptospira, were detected in those fluids and in the sera. At the same time, the corneas of the horses began to develop a diffuse opacity. This finding of anti- leptospira antibodies in equine tears and aqueous humor shows the pathway along which they arrive at the cornea and bind to it. PMID- 3564364 CU - 91 SO - Vet Immunol Immunopathol 1987 Feb;14(2):181-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 87162213 AU - Arimitsu Y AU - Kobayashi S AU - Matuhasi T AU - Suzuki H AU - Yamaji Y AU - Suprasert S AU - Supawadee J TI - Epidemiological studies on leptospirosis in Chiang Mai (Thailand). LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agglutination Tests/methods MH - Antigens, Bacterial/isolation & purification MH - Child MH - Human MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/*epidemiology/immunology MH - Middle Age MH - Serotyping MH - Thailand RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 870427 DP - 1987 Feb IS - 0950-2688 TA - Epidemiol Infect PG - 97-100 SB - M CY - ENGLAND IP - 1 VI - 98 JC - EPI AA - Author EM - 8707 AB - A total of 270 serum samples collected in Chiang Mai province were examined for antibodies against leptospira using the microscopic agglutination test (MAT). Four of 40 serum specimens from patients who visited the hospital with the common cold, were positive with a titre of 20. Twelve (10.4%) of the 115 samples in the Doi Saket district showed a positive reaction. Only 2 of 115 sera of school children in Chiang Mai city had antibodies. Specific serovars detected were Leptospira hebdomadis (5), L. australis (3), L. icterohaemorrhagiae (2), L. bataviae (2), and one each of L. canicola, L. javanica and L. pyrogenes. One case of mixed infection with L. hebdomadis and L. javanica, and L. autumnalis and L. australis were observed. PMID- 3556441 CU - 91 SO - Epidemiol Infect 1987 Feb;98(1):97-100 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 87197860 AU - Ferreira Alves VA AU - Vianna MR AU - Yasuda PH AU - De Brito T TI - Detection of leptospiral antigen in the human liver and kidney using an immunoperoxidase staining procedure. LA - Eng MH - Adult MH - Antigens, Bacterial/*analysis MH - Human MH - Immunoenzyme Techniques MH - Kidney/analysis/*immunology/pathology MH - Leptospira interrogans/*immunology MH - Liver/analysis/*immunology/pathology MH - Middle Age MH - Support, Non-U.S. Gov't MH - Weil's Disease/immunology/pathology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 870611 DP - 1987 Feb IS - 0022-3417 TA - J Pathol PG - 125-31 SB - M CY - ENGLAND IP - 2 VI - 151 JC - JLB AA - Author EM - 8708 AB - Detection of leptospiral antigen using an immunoperoxidase staining (IP) procedure was carried out on fifteen samples of human liver, (nine from autopsies and six from biopsies) and nine samples of human kidneys (eight autopsies and one biopsy). The IP staining procedure to detect leptospiral antigen (L. interrogans serovar icterohaemorrhagiae) in human liver and kidney proved to be a reproducible method useful on paraffin embedded tissues after formalin, Bouin's or Helly's fluid fixation. Furthermore, the IP procedure on paraffin-embedded tissue appears to have potential as an aid to the diagnosis. IP stained leptospiral antigen was detected in portal spaces of the liver, engulfed by cells of the mononuclear phagocyte system, in the interstitium of the kidney, and lining vessel walls of both liver and kidney. The results suggest that in acute human leptospirosis (L. interrogans serovar icterohaemorrhagiae) the main factors in the pathogenesis of the lesions are related to the presence of organisms and/or their virulence, including products released by lysis. PMID- 3553506 CU - 91 SO - J Pathol 1987 Feb;151(2):125-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [34 medline neighbors] UI - 87141473 AU - Smith AW AU - Skilling DE AU - Benirschke K AU - Albert TF AU - Barlough JE TI - Serology and virology of the bowhead whale (Balaena mysticetus L.). LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/*analysis MH - Caliciviridae/*immunology MH - Cetacea/*microbiology MH - Leptospira interrogans/immunology MH - Orthomyxoviridae/immunology MH - Paramyxoviridae/immunology MH - Support, U.S. Gov't, Non-P.H.S. MH - Swine MH - Vesicular Exanthema of Swine/microbiology MH - Virus Cultivation MH - Whales/*microbiology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 870423 DP - 1987 Jan IS - 0090-3558 TA - J Wildl Dis PG - 92-8 SB - M CY - UNITED STATES IP - 1 VI - 23 JC - KEM AA - Author EM - 8706 AB - Sera from four bowhead whales (Balaena mysticetus L.) were examined for the presence of specific antibodies, and tissue and swab samples from six and four animals respectively were processed for isolation of viruses and for initiation of bowhead whale cell cultures. All sera were negative for antibodies to nine serovars of Leptospira interrogans and to 21 orthomyxovirus subtypes and a paramyxovirus (Newcastle disease virus). All sera were positive, however, for neutralizing antibodies to one or more calicivirus serotypes. Two untyped adenoviruses were isolated from colon samples of two different whales, but neutralizing antibodies to the agents could not be demonstrated in any sera. Three primary bowhead whale cell cultures were derived from kidney (two cultures) and testis (one culture), from three individual whales. PMID- 3820430 CU - 91 SO - J Wildl Dis 1987 Jan;23(1):92-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 87141468 AU - Baulu J AU - Everard CO AU - Everard JD TI - Leptospires in vervet monkeys (Cercopithecus aethiops Sabaeus) on Barbados. LA - Eng MH - Agglutinins/*analysis MH - Animal MH - Antibodies, Bacterial/*analysis MH - Barbados MH - Cercopithecus/*microbiology MH - Cercopithecus aethiops/*microbiology MH - Female MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Support, Non-U.S. Gov't RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870423 DP - 1987 Jan IS - 0090-3558 TA - J Wildl Dis PG - 60-6 SB - M CY - UNITED STATES IP - 1 VI - 23 JC - KEM AA - Author EM - 8706 AB - Agglutinins to Leptospira were found at titers of greater than or equal to 1:100 in 150 of 501 (29.9%) vervet monkeys (Cercopithecus aethiops sabaeus) bled within 1 mo of capture in Barbados. Including a further 34 of 145 bled within 1 yr of capture, the seropositivity prevalence was 28.5%. A further 35 monkeys (5.4%) had traces of agglutinins or gave titers of 1:50. The proportion of seropositive adults (41.5%) was more than twice that of seropositive immature monkeys (17.6%). Among adults, 49.2% of males and 35.7% of females were seropositive, while among juveniles proportions of seropositive males and females were similar (17.8% and 17.4%, respectively). Seropositivity prevalences tended to increase in proportion to rainfall. In each of 165 of the 184 positive sera, a single serogroup predominated in the serological reactions. These serogroups were Ballum (61%), Icterohaemorrhagiae (16%), Autumnalis (15%), Pyrogenes, Panama, Pomona, Tarassovi and Canicola (8% altogether). In the other 19 positive sera no single serogroup predominated. Serial bleeding showed that vervet monkeys can retain naturally-acquired antibodies to Leptospira for at least 2.5 yr. The evidence suggests that vervet monkeys in Barbados are transmitting leptospiral infections among themselves independently of other groups of animals, and are not a major source of human leptospirosis. PMID- 3820429 CU - 91 SO - J Wildl Dis 1987 Jan;23(1):60-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 88078586 AU - Cisternas JR AU - Milstein-Kuschnaroff T TI - The effect of human leptospirosis on the composition and concentration of serum lipids and lipoproteins. LA - Eng MH - Adult MH - Electrophoresis, Cellulose Acetate MH - Esterification MH - Human MH - Lecithin Acyltransferase/*blood MH - Leptospirosis/*blood/physiopathology MH - Lipids/*blood MH - Lipoproteins/*blood MH - Liver/*physiopathology MH - Male MH - Support, Non-U.S. Gov't RN - EC 2.3.1.43 (Lecithin Acyltransferase) RN - 0 (Lipoproteins) PT - JOURNAL ARTICLE DA - 880223 DP - 1987 IS - 0100-879X TA - Braz J Med Biol Res PG - 149-59 SB - M CY - BRAZIL IP - 2 VI - 20 JC - BOF AA - Author EM - 8804 AB - 1. Plasma lipids and lipoproteins were studied in 9 male patients during the immune phase of leptospirosis and 4 months later after recovery. 2. Electrophoretic patterns of plasma lipoproteins were characterized by the absence of alpha- and pre-beta lipoprotein bands and the presence of a single broad beta band. The high-density lipoprotein (HDL) fraction ran in the pre-beta position and triglyceride (TG) content was high. Low-density lipoproteins (LDL) moved into three different bands and were rich in TG. Very low-density lipoproteins (VLDLs) migrated normally and their triglyceride content was low. All lipoprotein fractions had low levels of cholesteryl esters. 3. In infected patients, the fractional lecithin:cholesterol acyltransferase (LCAT) rate (%/h) was low, while the molar LCAT rate (mumol 1(-1)h-1 remained unchanged. Both VLDL and LDL cholesterol levels increased while HDL cholesterol decreased. 4. These findings demonstrated that abnormalities in lipoprotein composition are associated with leptospiral liver injury. AD - Departamento de Fisiologia, Faculdade de Ciencias Medicas, Santa Casa de Sao Paulo, Brasil. PMID- 3690050 CU - 91 SO - Braz J Med Biol Res 1987;20(2):149-59 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 88065143 AU - Shimizu T AU - Matsusaka E AU - Nagakura N AU - Takayanagi K AU - Masuzawa T AU - Iwamoto Y AU - Morita T AU - Mifuchi I AU - Yanagihara Y TI - Chemical properties of lipopolysaccharide-like substance (LLS) extracted from Leptospira interrogans serovar canicola strain Moulton. LA - Eng MH - Amino Sugars/analysis MH - Bacterial Proteins/analysis MH - Carbohydrates/analysis MH - Chromatography, Gas MH - Comparative Study MH - Electrophoresis, Paper MH - Electrophoresis, Polyacrylamide Gel MH - Fatty Acids/analysis MH - Leptospira interrogans/*analysis MH - Lipids/analysis MH - Lipopolysaccharides/*analysis MH - Phosphorus/analysis MH - Sugar Acids/analysis RN - 0 (Amino Sugars) RN - 0 (Bacterial Proteins) RN - 0 (Fatty Acids) RN - 0 (Lipopolysaccharides) RN - 0 (Sugar Acids) RN - 1069-03-0 (2-keto-3-deoxyoctonate) RN - 7723-14-0 (Phosphorus) PT - JOURNAL ARTICLE DA - 880114 DP - 1987 IS - 0385-5600 TA - Microbiol Immunol PG - 717-25 SB - M CY - JAPAN IP - 8 VI - 31 JC - MX7 AA - Author EM - 8803 AB - The aqueous layer was isolated from Leptospira interrogans serovar canicola strain Moulton by the hot phenol-water method. After ultracentrifugation, the precipitate was designated as lipopolysaccharide-like substance (LLS) fraction and the chemical composition was compared with that of bacterial LPS. The LLS fraction consists of 35.2% carbohydrate, 3.8% amino sugar, 36.4% lipid, 15.2% protein, and 0.3% phosphorus. Neutral sugars were detected as rhamnose, arabinose, xylose, 4-O-methylmannose, mannose, galactose, and a small amount of erythrose, fucose and glucose by gas-liquid chromatography (GLC), but 2-keto-3-deoxyoctonic acid was not detected in the LLS by thiobarbituric acid test and high voltage paper electrophoresis. Fatty acids detected by GLC were decanoic acid (C10: 0), dodecanoic acid (C12: 0), dodecenoic acid (C12: 1), tridecenoic acid (C13: 1), tetradecanoic acid (C14: 0), hexadecanoic acid (C16: 0), hexadecenoic acid (C16: 1), and octadecenoic acid (C18: 1). With SDS-polyacrylamide gel electrophoresis, bacterial LPS showed many orderly bands, while the banding pattern of the leptospiral LLS was very simple. These findings demonstrate that the physicochemical properties and chemical composition of LLS fraction from Leptospira are different from those of LPS extracted from gram-negative bacteria such as Enterobacteriaceae, and suggesting that Leptospira has no typical LPS. AD - Department of Microbiology, Shizuoka College of Pharmacy. PMID- 3683216 CU - 92 SO - Microbiol Immunol 1987;31(8):717-25 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 88045017 AU - Khisamov GZ AU - Morozova GZ TI - [The role of enzymes of amino acid and lipid metabolism in Leptospira metabolism] LA - Rus MH - Amino Acids/*metabolism MH - Bacterial Proteins/metabolism MH - Comparative Study MH - Energy Metabolism MH - Fatty Acids/metabolism MH - Fatty Acids, Unsaturated/metabolism MH - Hydrolysis MH - Leptospira/*enzymology/growth & development/pathogenicity MH - Lipids/*metabolism RN - 0 (Amino Acids) RN - 0 (Bacterial Proteins) RN - 0 (Fatty Acids) RN - 0 (Fatty Acids, Unsaturated) PT - JOURNAL ARTICLE DA - 871127 DP - 1987 IS - 0002-3027 TA - Vestn Akad Med Nauk SSSR PG - 84-90 CY - USSR IP - 7 JC - X9A EM - 8802 PMID- 3673220 CU - 92 TT - Rol' fermentov obmena aminokislot i lipidov v metabolizme leptospir. SO - Vestn Akad Med Nauk SSSR 1987;(7):84-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 88024459 AU - Di Stanislao F AU - Maffei C AU - Strusi P AU - Lupidi R AU - Renga G TI - Human leptospirosis in an area of central Italy: results from a serological survey. LA - Eng MH - Adult MH - Antibodies, Bacterial/analysis MH - Comparative Study MH - Disease Outbreaks/*epidemiology MH - Female MH - Human MH - Italy MH - Leptospira interrogans/classification/immunology MH - Male MH - Middle Age MH - Risk Factors MH - Serotyping MH - Weil's Disease/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 871130 DP - 1987 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 134-8 SB - M CY - ITALY IP - 2 VI - 66 JC - AKG AA - Author EM - 8802 AB - The results of a serosurvey for leptospiral antibodies in a random sample of healthy subjects are reported. The study was carried out in an area where a waterborne outbreak of leptospirosis, due to leptospires of serogroup Australis, had occurred a month before. Sera were tested with the microagglutination technique. Leptospiral agglutinins were found in 13.8% of tested subjects, mostly in adult females. The highest prevalence rate was observed for serovar lora belonging to serogroup Australis. The leptospires of this group have a relevant spread in the study area in keeping with other surveys carried out in Italy. AD - Institute of Hygiene, School of Medicine, University of Ancona. PMID- 3663338 CU - 91 SO - Boll Ist Sieroter Milan 1987;66(2):134-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 87324619 AU - Ragnaud JM AU - Dupon M AU - Echinard E AU - Teboulle D AU - Wone C TI - [Pulmonary manifestations in severe ictero-hemorrhagic leptospirosis] LA - Fre MH - Adolescence MH - Adult MH - Aged MH - English Abstract MH - Female MH - Hemoptysis/etiology MH - Human MH - Lung Diseases/*etiology/pathology/radiography MH - Male MH - Middle Age MH - Time Factors MH - Weil's Disease/*complications/diagnosis/pathology PT - JOURNAL ARTICLE DA - 871019 DP - 1987 IS - 0003-410X TA - Ann Med Interne (Paris) PG - 282-6 SB - M CY - FRANCE IP - 4 VI - 138 JC - 5FZ AA - Author EM - 8712 AB - Eight cases of pulmonary involvement were observed in 17 severe cases of ictero-haemorrhagic leptospirosis. Haemoptysis (7 cases) occurred on the 4th day of the infectious syndrome and was associated with other haemorrhagic manifestations in 4 cases. Cough, pain and polypnoea were not constant. Chest X-ray showed diffuse, non-specific changes, such as nodular opacities or infiltrates. Septicaemia was confirmed in all cases with acute renal failure in 7 cases and meningitis in 6 cases. Severe thrombocytopenia was demonstrated in 2 cases. Six patients recovered quickly with regression of the lung changes within 12 days. Two patients died, one of a fulminant haemoptysis related to a disseminated intravascular coagulation syndrome, and the other of acute respiratory failure. All cases were confirmed serologically. Although lung changes in leptospirosis are usually benign and mild, haemoptysis and polypnoea with diffuse radiological changes are poor prognostic factors. The pathological changes were similar to those of haemorrhagic alveolitis. These changes may be either due to the liberation of toxins or to an immunological phenomenon. PMID- 3631826 CU - 90 TT - Manifestations pulmonaires au cours de leptospiroses ictero- hemorragiques severes. EA - A SO - Ann Med Interne (Paris) 1987;138(4):282-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 87303873 AU - Terpstra WJ AU - Njenga R AU - Korver H AU - Ligthart GS TI - ELISA for the detection of leptospirosis in Kenya. LA - Eng MH - Agglutination Tests MH - *Enzyme-Linked Immunosorbent Assay MH - Human MH - Kenya MH - Leptospirosis/*diagnosis MH - Predictive Value of Tests MH - Risk PT - JOURNAL ARTICLE DA - 871016 DP - 1987 Jan IS - 0012-835X TA - East Afr Med J PG - 49-54 CY - KENYA IP - 1 VI - 64 JC - EDG EM - 8712 PMID- 3622331 CU - 90 SO - East Afr Med J 1987 Jan;64(1):49-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 87302877 AU - Wanyangu SW AU - Palmer MF AU - Zochowski WJ AU - Waitkins SA TI - Comparison of the DIFCO and Patoc 1 slide antigens in the screening of leptospirosis. LA - Eng MH - *Agglutination Tests MH - Animal MH - *Antigens, Bacterial MH - Cattle MH - Cattle Diseases/diagnosis MH - Comparative Study MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/veterinary MH - Rodent Diseases/diagnosis MH - Rodentia RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 871014 DP - 1987 IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 155-61 SB - M CY - ENGLAND IP - 2 VI - 10 JC - DNN AA - Author EM - 8712 AB - A comparison of the Patoc 1 slide agglutination (SAT) and DIFCO slide agglutination test for the screening of leptospirosis in man, cattle and coypu (Myocastor coypus Molina) is reported. The economic costs, convenience and availability of the antigens for the tests are analysed. It is recommended that slide agglutination methods alone are not sufficient for the routine diagnosis of leptospirosis. PMID- 3621886 CU - 91 SO - Comp Immunol Microbiol Infect Dis 1987;10(2):155-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 87295472 AU - Drinovec J AU - Kandus A AU - Bren AF AU - Sinigoj M AU - Erzen I AU - Licina A AU - Kveder R AU - Ponokvar R AU - Mocivnik M AU - Benedik M TI - Acute renal failure in leptospirosis--a 12-year survey. LA - Eng MH - Adolescence MH - Adult MH - Female MH - Human MH - Kidney Failure, Acute/*etiology/therapy MH - Leptospirosis/*complications/epidemiology MH - Male MH - Middle Age MH - Prognosis MH - Yugoslavia PT - JOURNAL ARTICLE DA - 870916 DP - 1987 IS - 0065-2598 TA - Adv Exp Med Biol PG - 265-71 SB - M CY - UNITED STATES VI - 212 JC - 2LU AA - Author EM - 8711 AB - From the beginning of 1974 to the end of 1985 141 persons in Slovenia (population 1.9 million) contracted leptospirosis 49 patients were 50 years old or more. All the patients have survived. 8 male patients aged from 18 to 44 had more severe acute renal failure (ARF), 5 of whom were treated with hemodialysis. The authors found that this 100% survival rate did not agree with the findings of many other researches which quote a relatively high mortality rate among older patients. In all 8 patients kidney function was good 1 year or more after ARF. The authors consider that the survival of patients with ARF depends on early and appropriate supportive treatment, which also includes intensive hemodialysis. PMID- 3618362 CU - 88 SO - Adv Exp Med Biol 1987;212:265-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 87273770 AU - Cointet F AU - Gilles B AU - Dussarat G AU - Le Bris H AU - Martini L AU - Brethes B AU - Capdevielle P TI - [Human leptospirosis in New Caledonia and dependencies. Apropos of 57 cases observed between 1 June 1983 and 31 May 1985] LA - Fre MH - Adult MH - English Abstract MH - Female MH - Human MH - Leptospirosis/diagnosis/*epidemiology/therapy MH - Male MH - Middle Age MH - New Caledonia MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 870828 DP - 1987 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 28-37 SB - M CY - FRANCE IP - 1 VI - 80 JC - C4G AA - Author EM - 8711 AB - 57 cases of leptospirosis were diagnosed in New Caledonia (South Pacific French Territory) between June 1983 and May 1985. 25% cases are severe infections; thrombopenia and renal failure are frequently observed. Leptospires are found in blood or spinal or urine culture confirmed by haemagglutination tests on microplates (Martin et Petit). Epidemiological studies are being performed during 1985-1986 to devise preventive measures adapted to the territory. PMID- 3607996 CU - 88 TT - La leptospirose humaine en Nouvelle-Caledonie et Dependances. A propos de 57 cas observes en 2 ans, du 1er juin 1983 au 31 mai 1985. EA - A SO - Bull Soc Pathol Exot Filiales 1987;80(1):28-37 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 87263638 AU - Kirichenko PL AU - Kobyshcha IuV AU - Lenartovich LS TI - [Specialized services for leptospirosis patients] LA - Rus MH - Diagnostic Errors MH - Human MH - Leptospirosis/*prevention & control MH - Mobile Health Units/*organization & administration MH - Ukraine PT - JOURNAL ARTICLE DA - 870724 DP - 1987 IS - 0038-5077 TA - Sov Med PG - 59-61 CY - USSR IP - 3 JC - UW7 EM - 8710 PMID- 3603161 TT - Spetsializirovannaia pomoshch' bol'nym leptospirozom. SO - Sov Med 1987;(3):59-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 87248371 AU - Sebek Z AU - Grulich I AU - Valova M TI - To the knowledge of the common hamster (Cricetus cricetus Linne, 1758; Rodentia) as host of leptospirosis in Czechoslovakia. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Czechoslovakia MH - Disease Reservoirs/*veterinary MH - Female MH - *Hamsters/immunology MH - Leptospira/immunology MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Rodent Diseases/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870804 DP - 1987 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 97-105 SB - M CY - CZECHOSLOVAKIA IP - 2 VI - 34 JC - F2T AA - Author EM - 8710 AB - A total of 1288 hamsters (Cricetus cricetus), coming from two regions of Czechoslovakia, were serologically investigated on the presence of leptospirosis. In 1114 hamsters from eastern Slovakia, where an outbreak occurred and local populations lived quite atypically, there was 31.8% positivity, in 174 animals from central Moravia, where the populations were at higher levels but lived normally, the positivity amounted to 17.2%. The serological positivity increases proportionately to the weight, i.e. to the age of the animals. The serovar grippotyphosa was dominant in them (29.6% of examined hamsters), while 6.0% were positive for L. pomona, 1.0% for serovars from the serogroup Sejroe, 0.2% for L. sorex-jalna and L. bataviae respectively, and 0.1% for L. bratislava. The hamsters from central Moravia were positive only for the serovar grippotyphosa. Antibodies in lower titres against L. pomona, having the character of coagglutinations, were simultaneously detected in some hamsters positive for L. grippotyphosa. In Czechoslovakia the common hamster is one of the potential hosts of L. grippotyphosa, its importance increasing during severe outbreaks, when the incidence of infection with L. grippotyphosa in hamster populations increases and the animals inhabit most varied types of biotopes and transfer to synanthropic way of life. PMID- 3596398 CU - 91 SO - Folia Parasitol (Praha) 1987;34(2):97-105 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 87241090 AU - Carroll AG AU - Campbell RS TI - Reproductive and leptospiral studies on beef cattle in central Queensland. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Australia MH - Cattle/*physiology MH - Cattle Diseases/diagnosis/*epidemiology MH - Female MH - Leptospira/immunology MH - Leptospirosis/diagnosis/epidemiology/*veterinary MH - Rain MH - *Reproduction MH - Soil MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870626 DP - 1987 Jan IS - 0005-0423 TA - Aust Vet J PG - 1-5 SB - M CY - AUSTRALIA IP - 1 VI - 64 JC - 9IE AA - Author EM - 8709 AB - The effect of rainfall on reproductive performance in beef cattle and the effects of rainfall and soil type on the prevalence of leptospirosis in beef cattle in inland central Queensland are described. Low annual rainfall produced a significant (P less than 0.05) decrease in calf branding rates. Leptospirosis (due to serovar hardjo) was serologically more prevalent after rain and on farms with high water holding capacity soils but there was no significant difference in branding rates between cattle on high or low water holding capacity soils. As a secondary mid-year rainfall peak is a feature of the area, leptospirosis due to serovar hardjo will tend to spread when most of the breeding herd is in the last trimester of pregnancy. The prevalence of leptospirosis due to serovar pomona is significantly lower in the region. PMID- 3593131 CU - 91 SO - Aust Vet J 1987 Jan;64(1):1-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 87230431 AU - Fuchs WA AU - Guggenbichler JP TI - [Familial hemophagocytic lymphohistiocytosis (case report)] LA - Ger MH - Anemia, Hemolytic, Congenital/*genetics/pathology MH - Case Report MH - Diagnosis, Differential MH - Disseminated Intravascular Coagulation/*genetics/pathology MH - English Abstract MH - Female MH - Histiocytes/pathology MH - Human MH - Infant MH - Liver/pathology MH - Lymph Nodes/pathology MH - Lymphocytes/pathology MH - Macrophages/pathology MH - *Phagocytosis MH - Reticuloendotheliosis/*genetics/pathology MH - Spleen/pathology PT - JOURNAL ARTICLE DA - 870629 DP - 1987 IS - 0030-9338 TA - Padiatr Padol PG - 67-72 SB - M CY - AUSTRIA IP - 1 VI - 22 JC - OOY AA - Author EM - 8709 AB - This is the report of a female infant ten weeks of age, who was admitted to our hospital with hyperpyrexia, hemolytic anemia and disseminated intravascular coagulation. The further course of the disease was characterized by: continuing hemolysis resulting in severe normochromic, normocytic anemia, unrelenting disseminated intravascular coagulation, increasing hepato-splenomegaly with hyperbilirubinemia and ascites. No causative infectious organism could be identified. The infant died at the age of 14 weeks from respiratory insufficiency. Autopsy revealed massive hepato-splenomegaly, ascites and bilateral pneumonia. Histologic evaluation demonstrated lymphohistiocytic infiltrates of the periportal areas of the liver, the spleen and lymphnodes. Meninges were infiltered by macrophages with ingested erythrocytes. Differential diagnosis includes an infection with leptospira icterohemorrhagica (Weils disease) and erythrophagocytosis observed after various viral infections. Also histiocytosis X or malignant histiocytosis has to be taken into consideration. The most probable diagnosis in our patient is that of familiar hemophagocytic reticulosis although the familiarity in our patient was lacking. Intra vitam diagnosis can only be established by liver biopsy which could not be performed in our patient due to the severe coagulation disturbance. PMID- 3587993 CU - 88 TT - Familiare hamophagozytische Lymphohistiozytose (Ein Fallbericht). EA - A SO - Padiatr Padol 1987;22(1):67-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 87223468 AU - Dive AM AU - Bigaignon G AU - Reynaert M TI - Adult respiratory distress syndrome in leptospira icterohaemorrhagiae infection [letter] LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospira interrogans MH - Male MH - Respiratory Distress Syndrome, Adult/*diagnosis MH - Weil's Disease/*diagnosis PT - LETTER DA - 870626 DP - 1987 IS - 0342-4642 TA - Intensive Care Med PG - 214 SB - M CY - UNITED STATES IP - 3 VI - 13 JC - H2J EM - 8709 PMID- 3584652 CU - 91 SO - Intensive Care Med 1987;13(3):214 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 89181023 AU - Andrade J AU - Brandao AP TI - [Epidemiology of human leptospirosis, with special reference to greater Rio de Janeiro, Brazil, from 1970 to 1982] LA - Por MH - Adolescence MH - Adult MH - Aged MH - Brazil MH - Child MH - English Abstract MH - Female MH - Hemagglutination Tests MH - Human MH - Leptospira/classification MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Retrospective Studies MH - Serotyping MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 890421 DP - 1987 Jan-Mar IS - 0074-0276 TA - Mem Inst Oswaldo Cruz PG - 91-100 SB - M CY - BRAZIL IP - 1 VI - 82 JC - MRY AA - Author EM - 8907 AB - From 1970 to 1982, 884 cases of human leptospirosis were serologically diagnosed at the Leptospirosis Laboratory, Fundacao Oswaldo Cruz - FIOCRUZ, by means of the microscopic agglutination test. Of these patients, 775 were hospitalized in the city of Rio de Janeiro, and 109 were reported by other Brazilian cities. Icterohaemorrhagiae was the presumptive infecting serogroup most commonly encountered in greater Rio patients (76.4%) and in the others (41.3%). During this 13-year period, two Icterohaemorrhagiae strains were isolated. In greater Rio the illness predominated between January and April (53.7%), the male sex accounted for 89.9% of the cases, and patients ranging from 16 to 45 year-olds were the most affected (74.9%). AD - Instituto Oswaldo Cruz, Departamento de Bacteriologia, Rio de Janeiro, RJ, Brasil. PMID- 3507570 TT - Contribuicao ao conhecimento da epidemiologia da leptospirose humana, com especial referencia ao Grande Rio, Brasil, no periodo de 1970 a 1982. EA - A SO - Mem Inst Oswaldo Cruz 1987 Jan-Mar;82(1):91-100 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 89135104 AU - Ziegler K TI - Leptospirosis from the clinical viewpoint. LA - Eng MH - Adolescence MH - Adult MH - Human MH - Leptospirosis/diagnosis/*epidemiology/therapy MH - Male MH - Poland MH - Seasons PT - JOURNAL ARTICLE DA - 890330 DP - 1987 IS - 0324-8542 TA - Bull Inst Marit Trop Med Gdynia PG - 88-94 SB - M CY - POLAND IP - 1-2 VI - 38 JC - BKX AA - Author EM - 8906 AB - Epidemiological, clinical and microbiological data of 27 patients suffering from leptospirosis are presented. Because of the sporadic occurrence of the disease, diagnosis on admission was correct in only 18% of the patients. As proved by the agglutination test, most of the infections were due to serotype icterohaemorrhagiae, but in only one case could the leptospires be detected directly in the blood culture. In most of the cases the course of the disease was moderately severe with one fatality. Symptomatology and treatment are discussed. AD - W. Pieck University Rostock, GDR, Clinic of Internal Medicine. PMID- 3506438 SO - Bull Inst Marit Trop Med Gdynia 1987;38(1-2):88-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 88065144 AU - Shimizu T AU - Matsusaka E AU - Takayanagi K AU - Masuzawa T AU - Iwamoto Y AU - Morita T AU - Mifuchi I AU - Yanagihara Y TI - Biological activities of lipopolysaccharide-like substance (LLS) extracted from Leptospira interrogans serovar canicola strain Moulton. LA - Eng MH - Adjuvants, Immunologic/*pharmacology MH - Animal MH - Antineoplastic Agents/*pharmacology MH - B-Lymphocytes/drug effects MH - Cells, Cultured MH - Comparative Study MH - Female MH - *Leptospira interrogans MH - Lipopolysaccharides/immunology/*pharmacology/toxicity MH - Lymphocyte Transformation/drug effects MH - Male MH - Mice MH - Mice, Inbred BALB C MH - Mice, Inbred C57BL MH - Mitogens/*pharmacology MH - T-Lymphocytes/drug effects RN - 0 (Adjuvants, Immunologic) RN - 0 (Antineoplastic Agents) RN - 0 (Lipopolysaccharides) RN - 0 (Mitogens) PT - JOURNAL ARTICLE DA - 880114 DP - 1987 IS - 0385-5600 TA - Microbiol Immunol PG - 727-35 SB - M CY - JAPAN IP - 8 VI - 31 JC - MX7 AA - Author EM - 8803 AB - The biological activities of lipopolysaccharide-like substance (LLS) extracted from Leptospira interrogans serovar canicola strain Moulton by the hot phenol-water method were studied in mice. The addition of 12.5 micrograms/ml or more of LLS fraction increased the incorporation of [3H]thymidine into in vitro cultured spleen cells of C57BL/6 mice, while the activity of the LLS fraction was about 20 times weaker than that of Salmonella typhimurium lipopolysaccharide (LPS). Pretreatment of murine spleen cells with rabbit anti-mouse thymocyte antiserum did not diminish the mitogenic activity of leptospiral LLS, and the LLS could not increase the incorporation of [3H]thymidine into thymocytes, suggesting that LLS acts on a B-lymphocyte population of lymphocytes. When sheep erythrocytes and LLS fraction were injected intraperitoneally into BALB/c mice, LLS exhibited an enhancing effect on antibody response in vivo. However, lethal toxicity of the LLS fraction was about 500 times lower than that of LPS in C57BL/6 mice loaded with galactosamine. No antitumor activity of leptospiral LLS (250-1,000 micrograms/mouse) against the ascites form of Ehrlich carcinoma in ddY mice was observed. The biological activities of the LLS fraction from the organism were weaker than those of gram-negative bacterial LPS, suggesting that Leptospira possesses no typical LPS. AD - Department of Microbiology, Shizuoka College of Pharmacy. PMID- 3500390 CU - 92 SO - Microbiol Immunol 1987;31(8):727-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 88251803 AU - Kim JS TI - Leptospirosis: a newly identified disease in Korea. LA - Eng MH - Adult MH - Animal MH - Disease Outbreaks/*epidemiology MH - Female MH - Human MH - Korea MH - Leptospira interrogans/*isolation & purification MH - Male MH - Middle Age MH - Rodentia/microbiology MH - Water Microbiology MH - Weil's Disease/*epidemiology/microbiology PT - JOURNAL ARTICLE DA - 880809 DP - 1987 IS - 1010-5395 TA - Asia Pac J Public Health PG - 61-8 CY - HONG KONG IP - 1 VI - 1 JC - ASJ EM - 8810 PMID- 3452382 CU - 88 SO - Asia Pac J Public Health 1987;1(1):61-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 88209682 AU - Butylin VYu AU - Chepkij LP AU - Lenartovich LS TI - Urgent hemosorption in leptospirosis. LA - Eng MH - Creatine Kinase/blood MH - Diuresis MH - *Hemoperfusion MH - Hepatorenal Syndrome/blood/complications/therapy MH - Human MH - Leptospirosis/blood/complications/*therapy MH - Oliguria/blood/complications/therapy RN - EC 2.7.3.2 (Creatine Kinase) PT - JOURNAL ARTICLE DA - 880616 DP - 1987 IS - 0890-5533 TA - Biomater Artif Cells Artif Organs PG - 249-56 SB - M CY - UNITED STATES IP - 1 VI - 15 JC - BAC AA - Author EM - 8808 AB - Resistant oliguria with increasing serum creatine phosphokinase (CPK) level are the most important early signs of the development of acute renal failure in leptospirosis. This symptomocomplex must be considered as indication for urgent hemosorption. Diuresis and normalisation of creatine phosphokinase level are the criteria for accessing the efficiency of hemosorptions. AD - Kiev's Bogomolec Medical Institute, USSR. PMID- 3449141 CU - 90 SO - Biomater Artif Cells Artif Organs 1987;15(1):249-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 88170754 AU - Sebek Z AU - Bashiribod H AU - Chaffari M AU - Sepasi F AU - Sixl W TI - The occurrence of leptospirosis in Iran. LA - Eng MH - Age Factors MH - Animal MH - Antibodies, Bacterial/analysis MH - Female MH - Human MH - Iran MH - Leptospirosis/*epidemiology MH - Male MH - Serotyping MH - Zoonoses/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 880505 DP - 1987 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 498-503 SB - M CY - CZECHOSLOVAKIA IP - 4 Suppl VI - 31 JC - IEV AA - Author EM - 8807 AB - The author examined 2,448 human and 541 domestic animal sera from Iran serologically for leptospira antibodies. Human sera revealed a 3.3% positivity rate in titer levels of 1:100 and higher, namely with the serovare of the serogroups Australis 2.3%, Sejroe 0.8%, Grippotyphosa 0.2%, Icterohaemorrhagiae 0.1%, Canicola 0.1%, Autumnalis 0.4% and Javanica 0.04%; domestic animal sera revealed a 6.8% in titers of 1:800 and higher, namely with Icterohaemorrhagiae 3.8%, Grippotyphosa 1.4%, Sejroe 1.2% and Bataviae 0.4%. The positivity rate for men was 3.1% for women 3.6%. In Teheran the seropositivity was higher--3.6% as in Rasth, the capital of the Gilan province--1.9%. AD - National Reference Laboratory for Leptospirosis, Policlinic Jihlava CSSR, Czechoslovakia. PMID- 3443753 CU - 91 SO - J Hyg Epidemiol Microbiol Immunol 1987;31(4 Suppl):498-503 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 88098318 AU - Witczuk J TI - [Patients with leptospirosis treated in the Observation and Infectious Disease Clinic in Koszalin 1980-1985] LA - Pol MH - Adult MH - Child MH - English Abstract MH - Hospitalization MH - Human MH - Leptospirosis/diagnosis/*therapy MH - Male MH - Middle Age MH - Poland PT - JOURNAL ARTICLE DA - 880203 DP - 1987 IS - 0033-2100 TA - Przegl Epidemiol PG - 235-8 CY - POLAND IP - 2 VI - 41 JC - Q8T EM - 8804 PMID- 3423292 TT - Chorzy na leptospirozy leczeni w Oddziale Obserwacyjno-Zakaznym w Koszalinie w latach 1980-1985. EA - A SO - Przegl Epidemiol 1987;41(2):235-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 87302876 AU - Leon-Vizcaino L AU - Hermoso de Mendoza M AU - Garrido F TI - Incidence of abortions caused by leptospirosis in sheep and goats in Spain. LA - Eng MH - Abortion, Veterinary/*epidemiology/etiology MH - Agglutination Tests MH - Animal MH - Disease Outbreaks/*veterinary MH - Female MH - Fetus MH - Fluorescent Antibody Technique MH - *Goats MH - Leptospira/isolation & purification MH - Leptospirosis/complications/epidemiology/*veterinary MH - Placenta/microbiology/pathology MH - Pregnancy MH - Pregnancy Complications, Infectious/epidemiology/veterinary MH - Sheep MH - Sheep Diseases/*epidemiology/etiology MH - Spain PT - JOURNAL ARTICLE DA - 871014 DP - 1987 IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 149-53 SB - M CY - ENGLAND IP - 2 VI - 10 JC - DNN AA - Author EM - 8712 AB - From 1970 to 1985, 973 outbreaks of abortion in sheep and 262 outbreaks of abortion in goats from southern Spain were studied. Of these, 1.7 and 2.6% respectively were caused by leptospiras, chiefly by the serovar pomona (11 flocks of sheep, 64.7%, and six herds of goats, 75.0%) and in a lower proportion the serovars sejroe (three flocks of sheep 17.6%, and one herd of goats, 12.5%), icterohaemorrhagiae (two and one outbreaks respectively) and grippotyphosa in one ovine flock (5.8%). The mean rates of attach (X + SD) of abortions by leptospirosis have been estimated as 16.9 + 6.5% in ovine outbreaks and 20.7 + 8.3% among goats. PMID- 3304822 CU - 90 SO - Comp Immunol Microbiol Infect Dis 1987;10(2):149-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 89079125 AU - Vassilevska M AU - Atanassov N TI - On the taxonomy of some pathogenic and saprophytic leptospires. LA - Eng MH - Esterases/analysis MH - Leptospira/analysis/*classification/enzymology MH - Membrane Proteins/analysis MH - *Nomenclature RN - EC 3.1. (Esterases) RN - 0 (Membrane Proteins) PT - JOURNAL ARTICLE DA - 890206 DP - 1987 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 48-53 CY - BULGARIA IP - 2 VI - 29 JC - F19 EM - 8904 PMID- 3144489 CU - 92 SO - Folia Med (Plovdiv) 1987;29(2):48-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 89079124 AU - Vassilevska M TI - Protein composition of two strains of Leptospira at different stages of their development. LA - Eng MH - Leptospira/*analysis/growth & development/genetics MH - Membrane Proteins/*analysis RN - 0 (Membrane Proteins) PT - JOURNAL ARTICLE DA - 890206 DP - 1987 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 41-7 CY - BULGARIA IP - 2 VI - 29 JC - F19 EM - 8904 PMID- 3144488 CU - 92 SO - Folia Med (Plovdiv) 1987;29(2):41-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 87141472 AU - Kingscote BF AU - Yates WD AU - Tiffin GB TI - Diseases of wapiti utilizing cattle range in southwestern Alberta. LA - Eng MH - Alberta MH - Animal MH - Bovine Virus Diarrhea-Mucosal Disease/*epidemiology/transmission MH - Cattle MH - Cattle Diseases/*epidemiology/etiology/microbiology/parasitology MH - Deer/*microbiology MH - Dictyocaulus Infections/*epidemiology/transmission MH - Fascioloidiasis/*epidemiology/transmission MH - Infectious Bovine Rhinotracheitis/*epidemiology/transmission MH - Leptospirosis/epidemiology/transmission/*veterinary MH - Parainfluenza Virus 3, Human MH - Paramyxoviridae Infections/epidemiology/transmission/*veterinary MH - Sarcocystosis/epidemiology/transmission/*veterinary PT - JOURNAL ARTICLE DA - 870423 DP - 1987 Jan IS - 0090-3558 TA - J Wildl Dis PG - 86-91 SB - M CY - UNITED STATES IP - 1 VI - 23 JC - KEM AA - Author EM - 8706 AB - Specimens from 28 wapiti (Cervus elaphus canadensis) were collected by hunters in southwestern Alberta in 1984. Various tests were performed to detect infections and conditions that could affect cattle sharing the range or cause disease in wapiti. Serum antibodies were present against leptospiral serovars autumnalis (25%), bratislava (4%), and icterohaemorrhagiae (8%), and the viruses of bovine virus diarrhea (52%), infectious bovine rhinotracheitis (45%), and parainfluenza type 3 (13%). No serological evidence of bovine respiratory syncytial virus, Brucella, Anaplasma, bluetongue virus, or epizootic hemorrhagic disease virus was found, nor were any lesions of vesicular diseases, necrotic stomatitis or nutritional myopathy evident. Focal interstitial nephritis and sarcocystosis were diagnosed histologically in 40% and 75%, respectively, of the wapiti tested. The prevalence of giant liver flukes (Fascioloides magna) was 50% and of lungworms (Dictyocaulus viviparus) 32%. Leptospiral serology on cattle in the area did not indicate that wapiti or cattle were a serious source of infection to each other. The giant liver fluke was the parasite most likely to be amplified by wapiti for cattle. Within the limits of this study, the results indicated that wapiti in the Waterton area do not pose a disease threat to the cattle with which they range, but periodic observational studies in these wapiti would be a useful means of early detection of any changes in the interspecies relationship. PMID- 3029443 CU - 96 SO - J Wildl Dis 1987 Jan;23(1):86-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 87141471 AU - Zarnke RL AU - Ballard WB TI - Serologic survey for selected microbial pathogens of wolves in Alaska, 1975-1982. LA - Eng MH - Adenoviruses, Canine/immunology MH - Alaska MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - Brucella/immunology MH - Carnivora/*microbiology MH - Coxiella/immunology MH - Distemper Virus, Canine/immunology MH - Francisella tularensis/immunology MH - Leptospira interrogans/immunology MH - Parvoviridae/immunology MH - Rabies Virus/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 870423 DP - 1987 Jan IS - 0090-3558 TA - J Wildl Dis PG - 77-85 SB - M CY - UNITED STATES IP - 1 VI - 23 JC - KEM AA - Author EM - 8706 AB - Serum samples were collected from 116 wolves which were captured in southcentral Alaska during 1975 through 1982. Antibodies to the following infectious disease agents were found: infectious canine hepatitis virus-72 of 87 (81%), canine parvovirus type 2-0 of 55 (0%) through 1979 and 10 of 32 (31%) after 1979, Francisella tularensis-16 of 67 (25%), canine distemper virus-10 of 83 (12%), Coxiella burnetti-5 of 95 (5%), rabies virus-1 of 88 (1%), Brucella spp.-1 of 67 (1%), Leptospira interrogans-1 of 82 (1%). Apparently rabies, brucellosis, and leptospirosis were rare and had little effect on the wolf population. Conversely, the other five infections were comparatively common and may have had a negative impact on the health of specific individual wolves, but did not appear to influence the health of the population. PMID- 3029442 CU - 93 SO - J Wildl Dis 1987 Jan;23(1):77-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 88037047 AU - Khisamov GZ AU - Sheliastina NN TI - [Photometric determination of the concentration of Leptospira in liquid nutrient media] LA - Rus MH - Culture Media MH - English Abstract MH - Leptospira/*growth & development MH - Photometry/*methods RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 871216 DP - 1987 IS - 0023-6748 TA - Lab Delo PG - 624-7 CY - USSR IP - 8 JC - KYU EM - 8802 PMID- 2444760 CU - 95 TT - Fotometricheskoe opredelenie kontsentratsii leptospir v zhidnikh pitatel'nykh sredakh. EA - A SO - Lab Delo 1987;(8):624-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 87083855 AU - Skilbeck NW AU - Chappel RJ TI - Immunogold silver staining for visualization of leptospires in histologic sections. LA - Eng MH - Animal MH - Cattle MH - Female MH - Gold MH - Immunologic Techniques MH - Kidney/*microbiology MH - Leptospira interrogans/*isolation & purification MH - Opossums MH - Placenta/microbiology MH - Pregnancy MH - Silver MH - Staining MH - Support, Non-U.S. Gov't RN - 7440-22-4 (Silver) RN - 7440-57-5 (Gold) PT - JOURNAL ARTICLE DA - 870219 DP - 1987 Jan IS - 0095-1137 TA - J Clin Microbiol PG - 85-6 SB - M CY - UNITED STATES IP - 1 VI - 25 JC - HSH AA - Author EM - 8704 AB - An immunogold silver stain for leptospires in sections of Formalin- fixed, paraffin-embedded tissues is described. Leptospires were intensely stained, and nonspecific staining of the tissue background was negligible. PMID- 2432082 CU - 95 SO - J Clin Microbiol 1987 Jan;25(1):85-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 87079042 AU - Pinto M AU - Herzberg H AU - Barnea A AU - Shenberg E TI - Effects of partial hepatectomy on the immune responses in mice. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - *Antibody Formation MH - Antilymphocyte Serum MH - Gamma-Globulins/analysis MH - Hemagglutination Tests MH - Hemolytic Plaque Technique MH - Hepatectomy MH - Hypersensitivity, Delayed/immunology MH - *Immunity, Cellular MH - Leptospira/immunology MH - *Liver Regeneration MH - Mice MH - Skin/transplantation MH - Skin Transplantation MH - Transplantation Immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antilymphocyte Serum) RN - 0 (Gamma-Globulins) PT - JOURNAL ARTICLE DA - 870202 DP - 1987 Jan IS - 0090-1229 TA - Clin Immunol Immunopathol PG - 123-32 SB - M SB - X CY - UNITED STATES IP - 1 VI - 42 JC - DEA AA - Author EM - 8704 AB - Experiments were performed to investigate the immune responses occurring as a result of partial hepatectomy (HEP) in mice. On Day 12 mice subjected to HEP showed a twofold rise in serum levels of IgG when compared with sham-operated (ShO) controls. The effects of HEP on specific antibody production following a single immunization with sheep red blood cells (SRBCs) were investigated. An early appearance of direct (IgM) splenic plaque-forming cells (PFCs) and significantly elevated indirect (IgG) PFCs were found in HEP mice. Elevated, early- appearing mercaptoethanol-resistant (IgG) hemagglutinating antibodies were also demonstrated in the sera of HEP mice. In addition to these findings our study showed that humoral and cell-mediated responses are affected by HEP in opposing fashion. Partial hepatectomy performed immediately after skin grafting suppressed a first set allograft rejection in mice. Furthermore, inhibited delayed-type hypersensitivity (DTH) response against SRBCs, as evaluated by a footpad weight assay, was demonstrated in HEP mice compared with the ShO controls. When SRBC- primed mice were partially hepatectomized 15 days later, they responded in a manner typical of the secondary immune response, showing an increased production of indirect (IgG) splenic PFCs. A similar anamnestic response was observed in mice sensitized with leptospiral antigen 50 days prior to HEP or exposed to carbon tetrachloride (CCl4) hepatotoxin. The mice responded by elevated serum IgG-specific antibodies as measured by solid-phase enzyme-linked immunosorbent assay (ELISA). Since HEP induced in mice immunological disturbances similar to those associated with liver disease, it is suggested that partial hepatectomy creating liver deficiency followed by regeneration may be a useful experimental model to study the immune status of various forms of hepatic damage. PMID- 2431821 CU - 95 SO - Clin Immunol Immunopathol 1987 Jan;42(1):123-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 87126708 AU - Alexander AD AU - Rule PL TI - Penicillins, cephalosporins, and tetracyclines in treatment of hamsters with fatal leptospirosis. LA - Eng MH - Animal MH - Cephalosporins/*therapeutic use MH - Hamsters MH - Leptospira interrogans/drug effects MH - Mesocricetus MH - Penicillins/*therapeutic use MH - Tetracyclines/*therapeutic use MH - Weil's Disease/*drug therapy RN - 0 (Cephalosporins) RN - 0 (Penicillins) RN - 0 (Tetracyclines) PT - JOURNAL ARTICLE DA - 870319 DP - 1986 Dec IS - 0066-4804 TA - Antimicrob Agents Chemother PG - 835-9 SB - M CY - UNITED STATES IP - 6 VI - 30 JC - 6HK AA - Author EM - 8705 AB - A predictable 6- to 7-day course of a fatal Leptospira interrogans serovar bataviae infection in experimentally infected mature 110- to 150-g hamsters was used to evaluate the therapeutic efficacy of conventionally used and newer antibiotics. Active drugs were ampicillin, bacampicillin, cyclacillin, piperacillin, mezlocillin, doxycycline, chlortetracycline, cefotaxime, and moxalactam. Cephalexin, cefadroxil, cefamandole, and cefoperazone showed little or no activity in preliminary studies. In delayed treatment studies, all nine active drugs prevented death of hamsters even when treatment was delayed until 1 to 2.5 days before expected time of death. Leptospires in kidneys of surviving animals could be demonstrated in one or more hamsters treated with doxycycline, chlortetracycline, cyclacillin, and piperacillin, but in none of the animals treated with ampicillin, bacampicillin, mezlocillin, cefotaxime, and moxalactam. The potential usefulness of newer penicillins and cephalosporins, as well as ampicillin, chlortetracycline, and doxycycline, for treatment of severe leptospirosis is reported. PMID- 3813511 CU - 92 SO - Antimicrob Agents Chemother 1986 Dec;30(6):835-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 87121536 AU - Hogerzeil HV AU - De Geus A AU - Terpstra WJ AU - Korver H AU - Ligthart GS TI - Leptospirosis in rural Ghana: Part 2, Current leptospirosis. LA - Eng MH - Acute Disease MH - Adolescence MH - Adult MH - Aged MH - Case Report MH - Child MH - Child, Preschool MH - Female MH - Ghana MH - Human MH - Jaundice/etiology MH - Leptospira/classification MH - Leptospira interrogans/classification MH - Leptospirosis/*epidemiology/microbiology MH - Male MH - Middle Age MH - Serotyping MH - Weil's Disease/*epidemiology/microbiology PT - JOURNAL ARTICLE DA - 870306 DP - 1986 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 408-14 SB - M CY - NETHERLANDS IP - 4 VI - 38 JC - WGJ AA - Author EM - 8705 AB - In this second part of our study a search for cases of acute leptospirosis among hospital patients is described. Of 88 suspected cases of acute leptospirosis, four were confirmed serologically. Of 102 patients with jaundice occurring in a period in which maximal transmission of leptospires could be expected, current leptospirosis was confirmed in one and suspected in another patient. The high prevalence of antibodies against leptospires of different serogroups, described in the first part of the study, is in contrast with the low frequency of acute leptospirosis among hospital patients in the same area. This indicates that most cases of acute leptospirosis do not have a reason for seeking hospital care. A new serovar was isolated, for which the name agogo, reference strain Agogo, serogroup Djasiman, is proposed. PMID- 3810845 CU - 88 SO - Trop Geogr Med 1986 Dec;38(4):408-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 87067086 AU - Jevon TR AU - Knudson MP AU - Smith PA AU - Whitecar PS AU - Blake RL Jr TI - A point-source epidemic of leptospirosis. Description of cases, cause, and prevention. LA - Eng MH - Adult MH - Animal MH - Case Report MH - Doxycycline/therapeutic use MH - Female MH - Human MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*diagnosis/drug therapy/etiology/physiopathology MH - Male MH - Sports MH - Zoonoses/diagnosis/drug therapy RN - 564-25-0 (Doxycycline) PT - JOURNAL ARTICLE DA - 870112 DP - 1986 Dec IS - 0032-5481 TA - Postgrad Med PG - 121-2, 127-9 SB - A SB - M CY - UNITED STATES IP - 8 VI - 80 JC - PFK AA - Author EM - 8703 AB - Leptospirosis is a zoonotic disease that consists of fever, headache, myalgias, and multiple organ involvement, has varying clinical severity and morbidity, and can occur in epidemic form. Diagnosis is based on culture or serologic demonstration of recent infection. There is evidence that doxycycline therapy started early in the course of the disease favorably affects duration and severity. Antibiotic therapy is often initiated because of a strong suspicion of the disease, before bacteriologic or serologic confirmation of the diagnosis is completed. Public health measures play an important role in minimizing the incidence of leptospirosis. PMID- 3786273 SO - Postgrad Med 1986 Dec;80(8):121-2, 127-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 87291011 AU - de Souza D TI - [Floods and human leptospirosis in the municipality of Sao Paulo] LA - Por MH - Age Factors MH - Brazil MH - *Disasters MH - Disease Outbreaks MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - *Natural Disasters MH - Seasons MH - Sex Factors MH - *Urban Population PT - JOURNAL ARTICLE DA - 870910 DP - 1986 Dec IS - 0080-6234 TA - Rev Esc Enferm USP PG - 243-50 SB - N CY - BRAZIL IP - 3 VI - 20 JC - RSS EM - 8711 PMID- 3649857 CU - 90 LI - N TT - Consideracoes sobre enchentes e leptospirose humana no municipio de Sao Paulo. EA - A SO - Rev Esc Enferm USP 1986 Dec;20(3):243-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [46 medline neighbors] UI - 87192666 AU - Peng HR AU - Dai BM TI - [Freeze-replica study on the attachment of leptospires to cells in vivo] LA - Chi MH - Animal MH - *Attachment Sites (Microbiology) MH - Cell Membrane/ultrastructure MH - English Abstract MH - Freeze Fracturing MH - Guinea Pigs MH - Leptospira interrogans/*physiology/ultrastructure MH - Liver/*cytology MH - *Lysogeny MH - Microscopy, Electron MH - Support, Non-U.S. Gov't MH - Weil's Disease/microbiology PT - JOURNAL ARTICLE DA - 870618 DP - 1986 Dec IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 261-4 CY - CHINA IP - 4 VI - 17 JC - GEB EM - 8708 PMID- 3570259 CU - 90 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1986 Dec;17(4):261-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 87179879 AU - Lee MG AU - Char G AU - Dianzumba S AU - Prussia P TI - Cardiac involvement in severe leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Diagnosis, Differential MH - Female MH - Human MH - Leptospirosis/*complications/diagnosis MH - Male MH - Middle Age MH - Myocarditis/diagnosis/*etiology MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE DA - 870428 DP - 1986 Dec IS - 0043-3144 TA - West Indian Med J PG - 295-300 CY - JAMAICA IP - 4 VI - 35 JC - XN4 EM - 8707 PMID- 3564451 SO - West Indian Med J 1986 Dec;35(4):295-300 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 87164858 AU - Wanyangu SW AU - Waitkins SA AU - Palmer MF TI - Isolation of leptospires from a one week dead coypu (Myocastor coypus Molina). LA - Eng MH - Animal MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Rodentia/*microbiology MH - Support, Non-U.S. Gov't MH - Temperature PT - JOURNAL ARTICLE DA - 870518 DP - 1986 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 236-40 SB - M CY - TAIWAN IP - 4 VI - 13 JC - GTK AA - Author EM - 8707 AB - The isolation of L. Interrogans from a one week dead coypu is reported. The isolate was identified as a pathogenic strain of leptospira belonging to the Icterohaemorrhagiae serogroup. PMID- 3557835 SO - Int J Zoonoses 1986 Dec;13(4):236-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 87189399 AU - Gu CH TI - [Advances in the study of leptospirosis] LA - Chi MH - Animal MH - Human MH - *Leptospirosis/diagnosis/immunology/physiopathology PT - JOURNAL ARTICLE PT - REVIEW DA - 870611 DP - 1986 Dec IS - 0578-1426 TA - Chung Hua Nei Ko Tsa Chih PG - 766-8 CY - CHINA IP - 12 VI - 25 JC - D7V EM - 8708 RF - 20 PMID- 3552496 CU - 90 SO - Chung Hua Nei Ko Tsa Chih 1986 Dec;25(12):766-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 87151950 AU - Volina EG AU - Ivanov AP AU - Kiktenko VS AU - Tkachenko EA AU - Arutiunova GA TI - [The use of direct immunoenzyme analysis with genus-specific peroxidase conjugate in leptospirosis] LA - Rus MH - Animal MH - Antigens, Bacterial/*analysis MH - English Abstract MH - Guinea Pigs MH - Hamsters MH - Immunization MH - Immunoenzyme Techniques MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Mesocricetus MH - Species Specificity RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 870330 DP - 1986 Dec IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 72-5 SB - M CY - USSR IP - 12 JC - Y9O AA - Author EM - 8706 AB - For the first time anti-Patoc I peroxidase conjugate was obtained from the serum of a hyperimmunized guinea pig by the method of Nakane and Kawaoi (1974) in the modification of Mathiesen et al. (1978). In the experimental study of 37 Leptospira strains belonging to 19 serological groups, carried out with the use of direct EIA techniques, anti-Patoc I peroxidase conjugate was found to be genus-specific and highly active. The possibility of detecting Leptospira antigens of 7 serological groups in the blood and in suspensions of the liver and kidneys of golden hamsters by direct EIA with the use of the above-mentioned conjugate was established. The use of direct EIA with anti-Patoc I peroxidase conjugate for the diagnosis of leptospirosis is recommended. PMID- 3548174 CU - 91 TT - Primenenie priamogo immunofermentnogo analiza s rodospetsificheskim peroksidaznym kon''iugatom pri leptospiroze. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1986 Dec;(12):72-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 87108803 AU - Palit A AU - Haylock LM AU - Cox JC TI - Storage of pathogenic leptospires in liquid nitrogen. LA - Eng MH - Dimethyl Sulfoxide/pharmacology MH - Freezing MH - Glycerin/pharmacology MH - Leptospira interrogans/drug effects/*growth & development/pathogenicity MH - Nitrogen MH - *Preservation, Biological MH - Virulence RN - 56-81-5 (Glycerin) RN - 67-68-5 (Dimethyl Sulfoxide) RN - 7727-37-9 (Nitrogen) PT - JOURNAL ARTICLE DA - 870323 DP - 1986 Nov IS - 0021-8847 TA - J Appl Bacteriol PG - 407-11 SB - M CY - ENGLAND IP - 5 VI - 61 JC - HDJ AA - Author EM - 8705 AB - The virulence and viability of various serovars of Leptospira interrogans were successfully preserved by storage in liquid nitrogen. Dimethyl sulphoxide at a final concentration of 2.5% (v/v) was added as cryoprotectant to a culture of leptospires grown in Ellinghausen- McCullough-Johnson-Harris medium. Ampoules were cooled at a controlled rate of 1 degree-3 degrees C/min to -70 degrees C, then transferred to the liquid phase of a liquid nitrogen storage unit. Glycerol was discounted as a cryoprotectant as it was found to be approximately 10 times more toxic than dimethyl sulphoxide to four of five serovars used in this study. The viability of nine strains has so far been observed over a period of 8-22 months storage in liquid nitrogen and full viability of all strains has been preserved over this period. Virulence of strains of serovars pomona and hardjo was well preserved, as demonstrated by challenge tests in guinea pigs and domestic pigs. PMID- 3804861 SO - J Appl Bacteriol 1986 Nov;61(5):407-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [69 medline neighbors] UI - 87096226 AU - Isogai E AU - Isogai H AU - Ito N TI - Decreased lipopolysaccharide content and enhanced susceptibility of leptospiras to serum leptospiricidal action and phagocytosis after treatment with diphenylamine. LA - Eng MH - Aniline Compounds/*pharmacology MH - Animal MH - *Blood Bactericidal Activity MH - Diphenylamine/*pharmacology MH - Leptospira interrogans/analysis/*drug effects/immunology MH - Lipopolysaccharides/*analysis MH - Mice MH - *Phagocytosis MH - Weil's Disease/immunology RN - 0 (Aniline Compounds) RN - 0 (Lipopolysaccharides) RN - 122-39-4 (Diphenylamine) PT - JOURNAL ARTICLE DA - 870210 DP - 1986 Nov IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 438-47 SB - M CY - GERMANY, WEST IP - 4 VI - 262 JC - Y55 AA - Author EM - 8704 AB - Growth of leptospiras in the presence of diphenylamine (DPA) caused a decrease in the content of leptospiral lipopolysaccharide (LPS). In association with this decrease of LPS, leptospiras became susceptible to anti-leptospiral action of normal rabbit serum (NRS), leptospiricidal action of antibody and complement, and killing by phagocytes. DPA-treated leptospiras were eliminated rapidly from the blood of infected mice and could not grow in the animals. PMID- 3799092 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1986 Nov;262(4):438-47 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 87095546 AU - Hartman EG AU - van den Ingh TS AU - Rothuizen J TI - Clinical, pathological and serological features of spontaneous canine leptospirosis. An evaluation of the IgM- and IgG-specific ELISA. LA - Eng MH - Animal MH - Dog Diseases/diagnosis/*immunology MH - Dogs MH - Enzyme-Linked Immunosorbent Assay MH - IgA/*analysis MH - IgM/*analysis MH - Leptospirosis/diagnosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 870204 DP - 1986 Nov IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 261-71 SB - M CY - NETHERLANDS IP - 3 VI - 13 JC - XCB AA - Author EM - 8704 AB - The clinical, pathomorphological and serological features of acute canine leptospirosis are evaluated and the IgM- and IgG-specific ELISA for leptospirosis serology in dogs is assessed. The clinical syndrome of acute canine leptospirosis was characterized by depression, anorexia, vomiting and often haemorrhagic diarrhoea. In addition, jaundice, uraemia, elevated creatinine and alkaline phosphatase were observed in the majority of the dogs. In pups invagination of the intestines was a noteworthy finding. The clinical signs and the post- mortem findings were rather non-specific so that the clinical and post- mortem diagnosis had to be confirmed serologically. In acute clinical cases of canine leptospirosis a high anti-leptospiral IgM titre, ranging from 160 in pups to 10240 in adults, was always present, whereas the anti-leptospiral IgG titre and the agglutination titre usually were negative or low. Dogs died from leptospirosis in spite of a high anti-leptospiral IgM titre. Only two dogs having, at the first examination, a high IgM titre in conjunction with a high IgG titre survived an acute infection. The possible role of IgM and IgG in the pathogenesis of an acute leptospiral infection is discussed. Different serological patterns in reference dogs, which were not suffering from acute leptospirosis, are presented. PMID- 3798734 SO - Vet Immunol Immunopathol 1986 Nov;13(3):261-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 87076427 AU - Waitkins SA TI - Leptospirosis as an occupational disease. LA - Eng MH - Agricultural Workers' Diseases/transmission MH - Animal MH - Cattle MH - Cattle Diseases/transmission MH - Dairying MH - Human MH - Leptospira interrogans/classification MH - Leptospirosis/*transmission/veterinary MH - Occupational Diseases/*transmission MH - Sports MH - Water Pollution MH - Weil's Disease/transmission PT - JOURNAL ARTICLE DA - 870204 DP - 1986 Nov IS - 0007-1072 TA - Br J Ind Med PG - 721-5 SB - M CY - ENGLAND IP - 11 VI - 43 JC - AXS EM - 8704 PMID- 3790454 SO - Br J Ind Med 1986 Nov;43(11):721-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 87071583 AU - Adler B AU - Faine S AU - Christopher WL AU - Chappel RJ TI - Development of an improved selective medium for isolation of leptospires from clinical material. LA - Eng MH - Animal MH - Antibiotics/pharmacology MH - *Culture Media MH - Leptospira interrogans/drug effects/*isolation & purification MH - Microbial Sensitivity Tests MH - Support, Non-U.S. Gov't RN - 0 (Antibiotics) RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 870116 DP - 1986 Nov IS - 0378-1135 TA - Vet Microbiol PG - 377-81 SB - M CY - NETHERLANDS IP - 4 VI - 12 JC - XBW AA - Author EM - 8703 AB - Standard albumin-Tween 80 medium (EMJH) for growth of leptospires was modified by the addition of six antibiotics to produce a superior, selective medium for primary isolation of leptospires of serovars hardjo and pomona of Leptospira interrogans from clinical material. PMID- 3788051 CU - 91 SO - Vet Microbiol 1986 Nov;12(4):377-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 87071582 AU - van den Ingh TS AU - Hartman EG TI - Pathology of acute Leptospira interrogans serotype icterohaemorrhagiae infection in the Syrian hamster. LA - Eng MH - Acute Disease MH - Animal MH - Fluorescent Antibody Technique MH - *Hamsters MH - Kidney/microbiology/pathology/ultrastructure MH - Leptospira interrogans/*isolation & purification/ultrastructure MH - Liver/microbiology/pathology/ultrastructure MH - *Mesocricetus MH - Rodent Diseases/microbiology/*pathology MH - Weil's Disease/microbiology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 870116 DP - 1986 Nov IS - 0378-1135 TA - Vet Microbiol PG - 367-76 SB - M CY - NETHERLANDS IP - 4 VI - 12 JC - XBW AA - Author EM - 8703 AB - The pathology of acute Leptospira interrogans serotype icterohaemorrhagiae infection in the Syrian hamster was investigated up to 7 days after infection using histology, electron microscopy and an indirect fluorescence test for leptospires. The disease was characterized by the presence of many leptospires in the tissues, jaundice, leukocytosis, haemorrhages, endothelial alteration and thrombotic glomerulopathy. The leptospires were present intravascularly, in the interstitium penetrating between liver cells and tubular epithelial cells and in the tubular lumina. The presence of leptospires was not necessarily associated with lesions. These findings support both pathogenetic mechanisms suggested in the literature, namely: the ability of leptospires to penetrate actively between cells with detachment of tight junctions, without obvious lesions to the cells, and an immune-mediated process with immune complex formation and binding and activation of complement resulting in leukocytosis, thrombotic glomerulopathy, endothelial alteration and haemorrhages. PMID- 3538643 CU - 90 SO - Vet Microbiol 1986 Nov;12(4):367-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 89122758 AU - Woolf A AU - Gremillion-Smith C TI - Pathologic findings in rabies-suspect, random-source, and accidentally killed skunks. LA - Eng MH - Accidents, Traffic MH - Animal MH - Brain/pathology MH - *Carnivora MH - Kidney/pathology MH - Liver/pathology MH - Lung/pathology MH - Rabies/epidemiology/*veterinary MH - *Skunks MH - Wounds and Injuries/pathology/*veterinary PT - JOURNAL ARTICLE DA - 890322 DP - 1986 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1089-91 SB - M CY - UNITED STATES IP - 9 VI - 189 JC - HAV AA - Author EM - 8905 AB - To evaluate sampling biases, pathologic findings in accidentally killed skunks (ie, killed by motor vehicles) were compared with those in random-source skunks (live-trapped and euthanatized, or trap-killed during research) and skunks submitted to a public health laboratory as rabies-suspect. Presence or absence of microscopic lesions in the brain, kidneys, liver, and lungs were used to test the null hypothesis that prevalence of disease did not differ by source of collection. Brain lesions differed with the source; rabid and nonrabid skunks submitted to a public health laboratory had higher prevalences of lesions than did other skunks. Kidney, liver, and lung lesions did not differ among skunks by source of collection. Liver and lung lesions were attributed mainly to parasitism, were not severe, and did not cause debilitated condition. Lesions were seen more often in the kidneys than in other tissues. Usually, lesions were mild to severe, focal, chronic, nonsuppurative, interstitial nephritis (possibly a consequence of leptospirosis). Six of 177 skunks necropsied appeared cachectic. Aleutian disease was diagnosed in one skunk and histoplasmosis was diagnosed in another, but rabies and canine distemper virus infection were the only diseases found with the potential to cause the high population mortality. Public health surveillance cases were biased toward diseased animals (rabies and canine distemper virus infection), but random-source or accidentally killed animals provided unbiased data. Although other factors must be considered, accidentally killed skunks provided cost-effective and useful data for the evaluation of enzootic rabies. AD - Cooperative Wildlife Research Laboratory, Southern Illinois University, Carbondale 62901. PMID- 3505935 CU - 90 NP - X SO - J Am Vet Med Assoc 1986 Nov 1;189(9):1089-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 89122738 AU - Corn JL AU - Swiderek PK AU - Blackburn BO AU - Erickson GA AU - Thiermann AB AU - Nettles VF TI - Survey of selected diseases in wild swine in Texas. LA - Eng MH - Animal MH - Animals, Wild MH - Brucellosis/epidemiology/veterinary MH - Female MH - Leptospirosis/epidemiology/veterinary MH - Male MH - Pseudorabies/epidemiology MH - Support, U.S. Gov't, Non-P.H.S. MH - Swine MH - Swine Diseases/*epidemiology MH - Texas PT - JOURNAL ARTICLE DA - 890322 DP - 1986 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1029-32 SB - M CY - UNITED STATES IP - 9 VI - 189 JC - HAV AA - Author EM - 8905 AB - Tissue, fecal, and serum specimens and swabs of nasal turbinates and tracheas were collected from 100 wild swine (Sus scrofa) from 10 populations in Texas and, along with 24 additional serum specimens, were evaluated for selected swine diseases. Swine positive for pseudorabies were detected in 7 populations. Brucella suis biovar 1 was isolated from 4 swine from 2 populations, but positive serologic results may indicate a more widespread distribution of the organism. All populations contained swine that were positive for leptospirosis. Trichinella spiralis was not found in the swine evaluated. AD - Department of Parasitology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602. PMID- 3505919 NP - X SO - J Am Vet Med Assoc 1986 Nov 1;189(9):1029-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 89218852 AU - Westblom TU AU - Everett ED AU - Satalowich FT TI - Leptospirosis. A 10-year experience. LA - Eng MH - Adult MH - Aged MH - Antibiotics/therapeutic use MH - Case Report MH - Female MH - Human MH - Leptospirosis/*diagnosis/drug therapy/physiopathology MH - Male MH - Middle Age MH - Missouri RN - 0 (Antibiotics) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, TUTORIAL DA - 890602 DP - 1986 Nov IS - 0026-6620 TA - Mo Med PG - 744-7 CY - UNITED STATES IP - 11 VI - 83 JC - NEW EM - 8908 RF - 12 PMID- 3334070 CU - 91 NP - X SO - Mo Med 1986 Nov;83(11):744-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 87096314 AU - Gol'denshtein ZA AU - Strikhanov SN AU - Mazhnikova GI AU - Kovalenko IuG AU - Boichuk LV TI - [Role of serodiagnosis in recognizing atypical forms of leptospirosis in Krasnodar Territory] LA - Rus MH - Adolescence MH - Adult MH - Agricultural Workers' Diseases/diagnosis/epidemiology MH - Child MH - Comparative Study MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis/epidemiology MH - Male MH - Middle Age MH - Risk MH - Russia MH - Serodiagnosis MH - Weil's Disease/diagnosis/epidemiology PT - JOURNAL ARTICLE DA - 870219 DP - 1986 Nov IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 63-5 SB - M CY - USSR IP - 11 JC - Y9O AA - Author EM - 8704 AB - The work deals with the epidemiological situation with respect to Leptospira infections in the Krasnodar territory. The work demonstrates that, in comparison with 1960-ies characterized by the prevalence of diseases caused by L. pomona and L. grippotyphosa, in 1970-ies the increase of the specific proportion of infections caused by L. icterohaemorrhagiae was registered. In recent 5 years (1980-1984) this leptospirosis constituted 73.5-94.8% of the total morbidity rate in the territory. Such situation was caused by active prophylactic measures in cattle breeding, as well as by the increase of the number of leptospirosis foci, appearing as the result of human activities and providing favorable conditions for the life and multiplication of Norway rats, the main source of infection caused by L. icterohaemorrhagiae as indicated by the fact that up to 23.9% of the Norway rats examined in this study proved to be contaminated. The detection of cases of leptospirosis among febrile patients and mistakes in clinical diagnosis confirm the necessity of the serological examination of febrile patients with the acute onset of the disease with temperature reaching 38 degrees C and higher for 3-5 days and the clinical picture of the disease being unclear in order to find out patients presenting with the atypical clinical picture of leptospirosis. PMID- 2948357 CU - 92 TT - Rol' serodiagnostiki v raspoznavanii atipichnykh form leptospirozov v Krasnodarskom krae. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1986 Nov;(11):63-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 87036759 AU - Jost BH AU - Adler B AU - Vinh T AU - Faine S TI - A monoclonal antibody reacting with a determinant on leptospiral lipopolysaccharide protects guinea pigs against leptospirosis. LA - Eng MH - Animal MH - Antibodies, Monoclonal/*immunology MH - Antibody Specificity MH - Electrophoresis, Polyacrylamide Gel MH - Epitopes/immunology MH - Female MH - Guinea Pigs MH - Immunization, Passive MH - Leptospira interrogans/*immunology MH - Lipopolysaccharides/*immunology MH - Male MH - Opsonins/immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/*prevention & control RN - 0 (Antibodies, Monoclonal) RN - 0 (Epitopes) RN - 0 (Lipopolysaccharides) RN - 0 (Opsonins) PT - JOURNAL ARTICLE DA - 861218 DP - 1986 Nov IS - 0022-2615 TA - J Med Microbiol PG - 269-75 SB - M CY - ENGLAND IP - 3 VI - 22 JC - J2N AA - Author EM - 8702 AB - An IgA monoclonal antibody (MUM/F1-1/copenhageni) was produced from a mouse immunised with Leptospira interrogans serovar copenhageni. The antibody showed partial serogroup specificity by agglutination and by reaction in enzyme immunoassay, and opsonised homologous leptospires for phagocytosis by cultured mouse macrophages. Immunodiffusion and Western-blotting experiments indicated that MUM/F1-1/copenhageni reacted with a carbohydrate determinant in the leptospiral lipopolysaccharide. Daily administration of purified MUM/F1- 1/copenhageni IgA before and after challenge with 2 X 10(8) virulent homologous leptospires passively protected newborn guinea pigs against lethal leptospirosis. PMID- 2430103 CU - 95 SO - J Med Microbiol 1986 Nov;22(3):269-75 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 87166074 AU - Goddard RD AU - Hopkins IG AU - Thornton DH TI - The development of a potency test for Leptospira hardjo vaccines: a comparison of protection in calves and serology in guinea-pigs. LA - Eng MH - Agglutination Tests/methods MH - Animal MH - Bacterial Vaccines/immunology/*standards MH - Cattle MH - Cattle Diseases/immunology/*prevention & control MH - Comparative Study MH - Dose-Response Relationship, Immunologic MH - Guinea Pigs MH - Immunization/prevention & control/*standards MH - Leptospira interrogans/*immunology MH - Quality Control RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 870506 DP - 1986 Oct IS - 0092-1157 TA - J Biol Stand PG - 337-44 SB - M CY - ENGLAND IP - 4 VI - 14 JC - HJD AA - Author EM - 8707 AB - The protective properties of two commercial Leptospira hardjo vaccines in calves were compared with the serological responses induced in guinea-pigs with a view to establishing a potency test based on serology. Groups of calves were given graded doses of the two vaccines and after eight weeks were challenged with virulent L. hardjo. Infection was monitored by microscopy and culture of urine and, eight weeks after challenge, by culture of the kidneys post mortem. Groups of guinea-pigs also were tested by the microscopic agglutination test (MAT). A clear dose response was observed and the response was related to the degree of protection achieved in the calves. The MAT titre in guinea-pigs indicative of an effective vaccine was calculated for the minimum dose of each vaccine that gave full protection in calves. A close correlation was observed. Two further batches of each vaccine were tested in guinea-pigs on two occasions with reproducible results. A potency test based on the MAT response of guinea-pigs is proposed. PMID- 3558417 CU - 91 SO - J Biol Stand 1986 Oct;14(4):337-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 89012303 AU - Kingscote BF TI - Leptospirosis in red foxes in Ontario. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Foxes/*microbiology MH - Leptospira interrogans/*immunology MH - Leptospirosis/epidemiology/immunology/pathology/*veterinary MH - Nephritis/pathology/veterinary MH - Ontario RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 881109 DP - 1986 Oct IS - 0090-3558 TA - J Wildl Dis PG - 475-8 SB - M CY - UNITED STATES IP - 4 VI - 22 JC - KEM AA - Author EM - 8901 AB - The role of the red fox (Vulpes vulpes) in the epizootiology of leptospirosis in southwestern Ontario was investigated in 1973-1974. Leptospira interrogans serovar pomona (kennewicki by DNA analysis) was isolated from the kidneys of three of eight foxes tested. Severe hemorrhagic nephritis and interstitial nephritis were common to these foxes and to five others out of nine foxes examined. Autumnalis antibodies were detected at titers 10(-2) to 10(-5) in 12 of 100 fox sera. Pomona antibodies occurred in 6% of the sera, always accompanied by autumnalis antibodies, and at titers never exceeding the autumnalis titers. Cultural, serological, and pathological findings together indicated that the red fox could have been acting as an amplifier host, but not as a maintenance host, for pomona. AD - Agriculture Canada, Animal Diseases Research Institute, Lethbridge, Alberta. PMID- 3503132 CU - 91 SO - J Wildl Dis 1986 Oct;22(4):475-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 87122522 AU - Kohler B AU - Pfitzner U AU - Schmidt H TI - [Incidence of leptospiroses caused by Leptospira interrogans serovar pomona in East Germany] LA - Ger MH - Cross-Sectional Studies MH - English Abstract MH - Germany, East MH - Human MH - Leptospira interrogans MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 870316 DP - 1986 Oct IS - 0049-8610 TA - Z Gesamte Hyg PG - 578-80 CY - GERMANY, EAST IP - 10 VI - 32 JC - XUO EM - 8705 PMID- 3492825 CU - 89 TT - Zum Vorkommen von Leptospirosen durch Leptospira interrogans Serovar pomona in der DDR. EA - A SO - Z Gesamte Hyg 1986 Oct;32(10):578-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 87233390 AU - Caballero A AU - Martin E AU - Sanchez RM AU - Romero J TI - [Experimental infection of Triatoma infestans (Hemiptera: Reduviidae) with Leptospira icterohaemorrhagiae and its transmission to laboratory mammals] LA - Spa MH - Animal MH - Comparative Study MH - English Abstract MH - Guinea Pigs MH - Insect Bites and Stings/complications MH - Insect Vectors/parasitology MH - Leptospira interrogans/*pathogenicity MH - Rabbits MH - Rats MH - Triatoma/*parasitology MH - Triatominae/*parasitology MH - Weil's Disease/*transmission PT - JOURNAL ARTICLE DA - 870714 DP - 1986 Oct-Dec IS - 0034-9771 TA - Rev Latinoam Microbiol PG - 381-4 CY - MEXICO IP - 4 VI - 28 JC - SEP EM - 8709 PMID- 3296076 CU - 90 TT - Infeccion experimental de Triatoma infestans (Hemiptera: Reduviidae) con Leptospira icterohaemorrhagiae y su trasmision a mamiferos de laboratorio. EA - A SO - Rev Latinoam Microbiol 1986 Oct-Dec;28(4):381-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 87007109 AU - Bernheimer AW AU - Bey RF TI - Copurification of Leptospira interrogans serovar pomona hemolysin and sphingomyelinase C. LA - Eng MH - Hemolysins/*isolation & purification MH - Leptospira/*analysis/enzymology MH - Phosphoric Diester Hydrolases/*isolation & purification MH - Sphingomyelin Phosphodiesterase/*isolation & purification MH - Support, Non-U.S. Gov't RN - EC 3.1.4 (Phosphoric Diester Hydrolases) RN - EC 3.1.4.12 (Sphingomyelin Phosphodiesterase) RN - 0 (Hemolysins) PT - JOURNAL ARTICLE DA - 861107 DP - 1986 Oct IS - 0019-9567 TA - Infect Immun PG - 262-4 SB - M SB - X CY - UNITED STATES IP - 1 VI - 54 JC - GO7 AA - Author EM - 8701 AB - The hemolytic and sphingomyelinase C activities of supernatants of cultures of Leptospira interrogans serovar pomona tended to copurify when isoelectric fractionation was carried out. Both activities focused primarily at pH 8.1. Considered in conjunction with other circumstantial evidence, the results led to the conclusion that sphingomyelinase C is responsible for hemolysis. PMID- 3019890 CU - 93 SO - Infect Immun 1986 Oct;54(1):262-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 89012310 AU - Kingscote BF AU - Bohac JG TI - Antibodies to bovine bacterial and viral pathogens in pronghorns in Alberta, 1983. LA - Eng MH - Alberta MH - Animal MH - Antelopes/*immunology MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - Artiodactyla/*immunology MH - Cattle MH - Cattle Diseases/microbiology MH - Diarrhea Virus, Bovine Viral/immunology MH - Herpesvirus 1, Bovine/immunology MH - Leptospira interrogans/immunology MH - Parainfluenza Virus 3, Human RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 881109 DP - 1986 Oct IS - 0090-3558 TA - J Wildl Dis PG - 511-4 SB - M CY - UNITED STATES IP - 4 VI - 22 JC - KEM AA - Author EM - 8901 AB - Sera from 210 pronghorns (Antilocapra americana) ranging in southeastern Alberta were tested for antibodies to disease agents present in indigenous cattle. No antibodies to Brucella abortus, Leptospira interrogans serovars pomona, hardjo, or grippotyphosa, or infectious bovine rhinotracheitis virus were found. Antibodies at prevalences of 43.8% and 49.2% were detected to bovine virus diarrhea (BVD) and parainfluenza type 3 (PI-3) viruses, respectively. The much higher prevalence of BVD virus antibodies in cattle than in pronghorns, and the occurrence of clinical bovine PI-3 infection in the study area, suggest that cattle may be a source of infection to the pronghorns. AD - Agriculture Canada, Animal Diseases Research Institute, Lethbridge, Alberta. PMID- 2845155 CU - 96 SO - J Wildl Dis 1986 Oct;22(4):511-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 87044007 AU - Bahaman AR AU - Ibrahim AL TI - Serological and bacteriological study of leptospiral infection in a cattle herd in Malaysia. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*epidemiology/microbiology MH - Leptospira/immunology/isolation & purification MH - Leptospira canicola/immunology/isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Malaysia RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 861218 DP - 1986 Sep 27 IS - 0042-4900 TA - Vet Rec PG - 325-6 SB - M CY - ENGLAND IP - 13 VI - 119 JC - XBS EM - 8702 PMID- 3776042 CU - 91 SO - Vet Rec 1986 Sep 27;119(13):325-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 87043999 AU - Egan J AU - Yearsley D TI - A serological survey of leptospiral infection in horses in the Republic of Ireland. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Horse Diseases/*epidemiology/immunology MH - Horses MH - Ireland MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/immunology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 861212 DP - 1986 Sep 20 IS - 0042-4900 TA - Vet Rec PG - 306 SB - M CY - ENGLAND IP - 12 VI - 119 JC - XBS EM - 8702 PMID- 3776036 CU - 91 SO - Vet Rec 1986 Sep 20;119(12):306 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 87072187 AU - Kmety E AU - Mochmann H TI - What is the correct specific epithet for pathogenic Leptospirae? LA - Eng MH - Human MH - Leptospira/*classification MH - Leptospira interrogans/*classification MH - *Nomenclature PT - JOURNAL ARTICLE DA - 870120 DP - 1986 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 298-303 SB - M CY - GERMANY, WEST IP - 3 VI - 262 JC - Y55 AA - Author EM - 8703 AB - The underlying documentation of the first descriptions of members of the genus Leptospira is carefully revised. Stimson's publication of? Spirochaeta interrogans (1907) is to be inadequate and not suitable to be recognized as the first valid description of a new genus being only a description of a spirochete-like microorganism without any documentation. The naming of the species of pathogenic leptospira interrogans is therefore not in confirmity with the requirements of the International Code of Nomenclature. The first valid description of saprophytic leptospira is given by Wolbach and Binger (1914) and that of pathogenic ones by Inada and Ido (1915). The correct name for the species of pathogenic leptospira is therefore icterohaemorrhagiae and for the saprophytic ones biflexa. PMID- 3788349 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1986 Sep;262(3):298-303 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [42 medline neighbors] UI - 87009183 AU - Thompson JC AU - Manktelow BW TI - Pathogenesis and red blood cell destruction in haemoglobinaemic leptospirosis. LA - Eng MH - Animal MH - Erythrocytes/*pathology/ultrastructure MH - Hamsters MH - Hematocrit MH - Hemoglobins/*analysis MH - Leptospirosis/*blood/etiology/pathology MH - Mesocricetus MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 861114 DP - 1986 Sep IS - 0021-9975 TA - J Comp Pathol PG - 529-40 SB - M CY - ENGLAND IP - 5 VI - 96 JC - HVB AA - Author EM - 8701 AB - Sequential morphological changes were seen in RBCs, spleen and liver from hamsters during the development of haemoglobinaemia following infection with Leptospira interrogans serovar ballum. Spleens from pre- haemoglobinaemic hamsters showed sequestration of RBCs and erythrophagocytosis but to a lesser degree than was seen in the haemoglobinaemic hamsters. Erythrophagocytosis and RBC sequestration were also seen in the liver, particularly in the haemoglobinaemic animals. None of these changes was seen in the RBCs, spleens and livers from moribund and dead hamsters suffering from non-haemoglobinaemic disease resulting from infection with Leptospira interrogans serovar pomona. Intracellular leptospires were readily identifiable within the spleens and livers of hamster infected with both ballum and pomona. It is suggested that leptospiral toxins affect RBC metabolism and eventually RBC morphology. The affected cells are detected and removed by the reticulo-macrophage system, usually before intravascular haemolysis can take place. If the toxins affect a certain enzyme or biochemical pathway, there are sufficient normal metabolic differences in RBCs between animals of different species and, in the same species of animal, between the same and different aged animals, to explain the differing susceptibilities of the RBCs to leptospiral toxins. PMID- 3760265 CU - 90 SO - J Comp Pathol 1986 Sep;96(5):529-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 87009182 AU - Thompson JC TI - Morphological changes in red blood cells of calves caused by Leptospira interrogans serovar pomona. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*blood MH - Erythrocytes/*pathology/ultrastructure MH - Female MH - Hemoglobins/analysis MH - Leptospira interrogans MH - Male MH - Microscopy, Electron MH - Weil's Disease/blood/*veterinary PT - JOURNAL ARTICLE DA - 861114 DP - 1986 Sep IS - 0021-9975 TA - J Comp Pathol PG - 517-27 SB - M CY - ENGLAND IP - 5 VI - 96 JC - HVB AA - Author EM - 8701 AB - Haemoglobinaemia is seen in certain hosts infected by certain serovars of Leptospira interrogans, but is absent from other serovar-host associations. Comparisons were made between calves infected with serovar pomona and those receiving a crude "toxin" prepared from the same organism. Red blood cells from "toxin"-injected calves showed discocyte-echinocyte transformation and contained portions of cytoplasm segregated within vacuoles. These animals showed increased sequestration of RBCs within the spleen but no overt haemoglobinaemia. Red blood cells from infected and haemoglobinaemic animals were spherical and pitted. They also showed vacuoles and tracts under the cell membrane in fully haemoglobinized RBCs and dark granular inclusions within the cytoplasm of those which were only partially haemoglobinized. Intracellular leptospires were not seen within the RBCs. Red blood cell sequestration and erythrophagocytosis were very pronounced within the spleen, liver and bone marrow. The changes in the RBCs are not easily explained by the previously proposed theory that RBC destruction is due to a phospholipase-like toxin acting directly upon the RBC membrane. A more appropriate hypothesis is that the RBC lesions are due to the adverse effects of leptospiral "toxin(s)" on the metabolism of the RBC causing the formation of defective portions of cytoplasm. These are then either degraded and expelled, leaving empty vacuoles, or are degraded and left within the cytoplasm as dark granular inclusions. PMID- 3760264 SO - J Comp Pathol 1986 Sep;96(5):517-27 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 87008964 AU - Schmid GP AU - Steere AC AU - Kornblatt AN AU - Kaufmann AF AU - Moss CW AU - Johnson RC AU - Hovind-Hougen K AU - Brenner DJ TI - Newly recognized Leptospira species ("Leptospira inadai" serovar lyme) isolated from human skin. LA - Eng MH - Aged MH - Animal MH - Biopsy MH - Case Report MH - Cebidae MH - Cercopithecus aethiops MH - Guinea Pigs MH - Hamsters MH - Human MH - Leptospira/*classification/isolation & purification/pathogenicity/ultrastructure MH - Lyme Disease/*microbiology MH - Male MH - Microscopy, Electron MH - Skin/*microbiology/pathology MH - Virulence PT - JOURNAL ARTICLE DA - 861117 DP - 1986 Sep IS - 0095-1137 TA - J Clin Microbiol PG - 484-6 SB - M CY - UNITED STATES IP - 3 VI - 24 JC - HSH AA - Author EM - 8701 AB - Leptospira strain 10, which represents a new Leptospira species, was isolated from a skin biopsy of a patient with Lyme disease. Although pathogenic for laboratory animals, the organism was not considered to have a significant role in the patient's illness. PMID- 3760144 CU - 90 SO - J Clin Microbiol 1986 Sep;24(3):484-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 87070834 AU - Skilbeck NW TI - Immunofluorescent staining of leptospires in pepsin treated histologic sections. LA - Eng MH - Animal MH - Antigens, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*diagnosis MH - Fluorescent Antibody Technique MH - Kidney/microbiology MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - *Pepsin A MH - Retrospective Studies MH - Swine MH - Swine Diseases/*diagnosis RN - EC 3.4.23.1 (Pepsin A) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 870120 DP - 1986 Sep IS - 0038-9153 TA - Stain Technol PG - 273-8 SB - M CY - UNITED STATES IP - 5 VI - 61 JC - V06 AA - Author EM - 8703 AB - A standard immunofluorescent method was modified for the staining of leptospires in formalin fixed, paraffin embedded tissues. Routine histologic sections were deparaffinized and treated with pepsin prior to staining. Pepsin treatment greatly enhanced subsequent staining of leptospires in naturally infected bovine and porcine tissues as well as in artificially infected tissues. Leptospires in naturally infected bovine tissues were usually undetectable in untreated sections but clearly visible in stained pepsin-treated sections. Naturally infected porcine kidney usually contained high levels of leptospiral antigen which could be stained without prior pepsin treatment. However, pepsin treatment of porcine tissues greatly increased the amount of leptospiral antigen detectable and made individual leptospires more conspicuous. The staining method could employ a single antiserum for the staining of leptospires from 13 serogroups. Also, leptospires could be stained in tissues stored in formalin for more than 14 months and in 26-year-old paraffin embedded tissues. PMID- 3097881 CU - 91 SO - Stain Technol 1986 Sep;61(5):273-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 87002697 AU - Jarekova J TI - [A proposal for the standardization of antigen density in the leptospira microagglutination test] LA - Slo MH - Agglutination Tests/*methods/standards MH - Antigens, Bacterial/immunology/*standards MH - English Abstract MH - Leptospira/immunology/*isolation & purification MH - Nephelometry and Turbidimetry RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 861120 DP - 1986 Sep IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 307-10 CY - CZECHOSLOVAKIA IP - 5 VI - 35 JC - CSH EM - 8701 PMID- 2944633 CU - 92 TT - Navrh na standardizaciu hustoty antigenu pre mikroaglutinacny test leptospir. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1986 Sep;35(5):307-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 87021733 AU - Fedorov EI AU - Haglov VA AU - Chepiga LP AU - Shvarsalon KN AU - Shumkova MS TI - [Morphology of a natural focus of Pomona leptospirosis in a steppe area] LA - Rus MH - Animal MH - Animals, Wild MH - Carrier State/microbiology/transmission/veterinary MH - Disease Reservoirs/*veterinary MH - Disease Vectors MH - Ecology MH - English Abstract MH - Leptospira/isolation & purification MH - Leptospirosis/microbiology/transmission/*veterinary MH - Seasons MH - Ukraine PT - JOURNAL ARTICLE DA - 861114 DP - 1986 Aug IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 32-5 SB - M CY - USSR IP - 8 JC - Y9O AA - Author EM - 8701 AB - The natural focus of Leptospira pomona infection has been found to include areas of the forest-meadow flood plain where the circulation of leptospires is constantly maintained among small mammals (the nucleus of the focus). A high level of Leptospira carriership (17.7%) among the animals has been registered in the central part of the flood plain and near the terraces, these areas having the most favorable conditions for the development of epizootic leptospirosis. PMID- 3765972 TT - Morfologiia prirodnogo ochaga leptospiroza Pomona stepnoi zony. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1986 Aug;(8):32-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 86321303 AU - Ellis WA AU - Thiermann AB TI - Isolation of leptospires from the genital tracts of Iowa cows. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology/parasitology MH - Female MH - Genitalia, Female/*parasitology MH - Iowa MH - Kidney/parasitology MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 861015 DP - 1986 Aug IS - 0002-9645 TA - Am J Vet Res PG - 1694-6 SB - M CY - UNITED STATES IP - 8 VI - 47 JC - 40C AA - Author EM - 8612 AB - Leptospira interrogans serovar hardjo was recovered from 5 of 11 nonpregnant cows chosen at random from an Iowa slaughterhouse. Isolations were made from the kidney in each instance, the genital tract of 3 cows: uterus from 1 cow, oviduct of another, and oviduct and uterus of a 3rd cow. PMID- 3752677 CU - 88 SO - Am J Vet Res 1986 Aug;47(8):1694-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 86281613 AU - Terpstra WJ AU - Schoone GJ AU - ter Schegget J TI - Detection of leptospiral DNA by nucleic acid hybridisation with 32P- and biotin-labelled probes. LA - Eng MH - Animal MH - Biotin/*diagnostic use MH - DNA, Bacterial/*analysis MH - Hamsters MH - Leptospira/*genetics/isolation & purification MH - Mesocricetus MH - *Nucleic Acid Hybridization MH - Phosphorus Radioisotopes/diagnostic use RN - 0 (DNA, Bacterial) RN - 0 (Phosphorus Radioisotopes) RN - 58-85-5 (Biotin) PT - JOURNAL ARTICLE DA - 860923 DP - 1986 Aug IS - 0022-2615 TA - J Med Microbiol PG - 23-8 SB - M CY - ENGLAND IP - 1 VI - 22 JC - J2N AA - Author EM - 8611 AB - Dot hybridisation with 32P- and biotin-labelled probes prepared from leptospiral DNA was performed to develop a sensitive and specific diagnostic method for early infection with leptospires. The smallest amounts of leptospiral DNA that could be detected with 32P- and biotin- labelled probes was 1.5 pg and 5 pg, respectively, corresponding to about 750 and 2500 leptospires. Dot hybridisation with a 32P-labelled probe detected leptospiral DNA in sera from all of 14 experimentally infected golden hamsters. The smallest amount of leptospiral DNA detected in these experiments corresponded to about 2500 leptospires. In the test conditions described in this study, the sensitivity of dot hybridisation with a biotin-labelled probe was lower. Little cross- hybridisation was observed with unrelated DNAs which indicates that dot hybridisation could be a useful diagnostic method. PMID- 3735387 CU - 92 SO - J Med Microbiol 1986 Aug;22(1):23-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 86279595 AU - Little TW AU - Stevens AE AU - Hathaway SC TI - Serological studies on British leptospiral isolates of the Sejroe serogroup. I. The identification of British isolates of the Sejroe serogroup by the cross agglutinin absorption test. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Cross Reactions MH - Great Britain MH - Human MH - Leptospira/*classification/immunology/isolation & purification MH - Rabbits MH - Serotyping MH - Swine PT - JOURNAL ARTICLE DA - 860925 DP - 1986 Aug IS - 0022-1724 TA - J Hyg (Lond) PG - 123-31 SB - M CY - ENGLAND IP - 1 VI - 97 JC - IEF AA - Author EM - 8611 AB - Using the cross agglutinin absorption test 12 British leptospiral isolates of the Sejroe serogroup were identified to serovar level. Six strains isolated from cattle, two from pigs and one from a human were identified as Leptospira interrogans serovar hardjo. Two isolates from wildlife were identified as Leptospira interrogans serovar saxkoebing. One further strain isolated from wildlife closely resembled serovar saxkoebing, but specific identification was not possible. These are the first reported isolations of serovar saxkoebing in the United Kingdom. The problems associated with the cross agglutinin absorption test, and possible alternative typing procedures are discussed. PMID- 3734440 SO - J Hyg (Lond) 1986 Aug;97(1):123-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 86317574 AU - Hathaway SC AU - Little TW AU - Pritchard DG TI - Problems associated with the serological diagnosis of Leptospira interrogans serovar hardjo infection in bovine populations. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis/epidemiology/microbiology MH - Female MH - Great Britain MH - Leptospirosis/diagnosis/epidemiology/*veterinary MH - Longitudinal Studies MH - Seasons MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 861022 DP - 1986 Jul 26 IS - 0042-4900 TA - Vet Rec PG - 84-6 SB - M CY - ENGLAND IP - 4 VI - 119 JC - XBS AA - Author EM - 8612 AB - Data combining sequential bacteriology and serology from a longitudinal study of a dairy herd were used to demonstrate the limitations of serology as a diagnostic method in cross-sectional sampling of bovine populations. Whole-herd point serological prevalences showed considerable variation over a two-year sampling period (38.8 to 76.2 per cent), and this was mainly due to varying age-specific prevalence. Owing to the rapid decline in titres and the varying persistence of infection, point serological prevalences failed to approximate to cumulative infection rates (either past or present) at different times of the year. A higher estimate of the number of susceptible animals in the herd than is the case results in inaccurate information on true incidence rates and can confuse assessments of the susceptibility of different age groups, especially if only small numbers are sampled. A sampling exercise demonstrated that a 10-cow sample usually provided little useful information other than establishing the presence or absence of hardjo in the herd. Increasing the sample size markedly improved epidemiological information, investigations of clinical disease, assessments of vaccination needs and public health tracebacks. Preferably 10 sera from each of the yearling, first calver, second calver and older age groups should be tested. Serology was an inadequate indicator of infection in individual animals. Group geometric mean titres taken from a mean serological response curve were shown to have limited application in the interpretation of field data, unless infection had occurred in the previous two months. PMID- 3750784 CU - 88 SO - Vet Rec 1986 Jul 26;119(4):84-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 86311425 AU - Jacobs JW AU - Korver H AU - Terpstra WJ TI - [Leptospirosis in a poultry slaughterhouse] LA - Dut MH - Abattoirs MH - Adult MH - Animal MH - Antibodies, Bacterial/analysis MH - Case Report MH - English Abstract MH - Female MH - Human MH - Leptospira interrogans/immunology MH - Male MH - Middle Age MH - Netherlands MH - Occupational Diseases/*etiology MH - Poultry MH - Weil's Disease/*diagnosis/epidemiology/transmission RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 861021 DP - 1986 Jul 26 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 1367-9 CY - NETHERLANDS IP - 30 VI - 130 JC - NUK EM - 8612 PMID- 3748223 CU - 91 TT - Leptospirose in een pluimveeslachterij. EA - A SO - Ned Tijdschr Geneeskd 1986 Jul 26;130(30):1367-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 87098578 AU - Artigou JY AU - Chauvet JP AU - Clergue F AU - Drobinski G AU - Grosgogeat Y TI - [Acute myocarditis disclosing leptospirosis] LA - Fre MH - Acute Disease MH - Adult MH - Case Report MH - Echocardiography MH - Electrocardiography MH - English Abstract MH - Hemodynamics MH - Human MH - Leptospirosis/complications/diagnosis/pathology MH - Male MH - Myocarditis/*diagnosis/etiology/pathology MH - Shock, Cardiogenic/diagnosis/etiology/pathology PT - JOURNAL ARTICLE DA - 870218 DP - 1986 Jul-Sep IS - 0003-3928 TA - Ann Cardiol Angeiol (Paris) PG - 387-9 SB - M CY - FRANCE IP - 7 VI - 35 JC - 502 AA - Author EM - 8704 AB - A 44 year old patient presents with acute myocarditis and cardiogenic shock. The evolution is progressively favorable at the price of a residual involvement of the left ventricular function, evolving to a dilated cardiopathy, within three years. The responsibility of an advanced ictero-hemorrhagic leptospirosis is established. The severity of this myocarditis and the revealing characteristics of the leptospirosis are peculiar to this observation which is discussed in terms of data from the literature. PMID- 3800282 TT - Myocardite aigue revelant une leptospirose. EA - A SO - Ann Cardiol Angeiol (Paris) 1986 Jul-Sep;35(7):387-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 87061603 AU - Hanada K AU - Hasimoto I AU - Katabira Y AU - Yamaguchi T AU - Sagara M TI - [A case of Leptospirosis (pretibial fever)] LA - Jpn MH - Adult MH - Case Report MH - Human MH - Leptospirosis/diagnosis/*pathology MH - Male MH - Skin/*pathology PT - JOURNAL ARTICLE DA - 870107 DP - 1986 Jul IS - 0021-499X TA - Nippon Hifuka Gakkai Zasshi PG - 805-9 CY - JAPAN IP - 8 VI - 96 JC - KJE EM - 8703 PMID- 3784051 SO - Nippon Hifuka Gakkai Zasshi 1986 Jul;96(8):805-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 87021671 AU - Broughton ES AU - Flack LE TI - The susceptibility of a strain of Leptospira interrogans serogroup icterohaemorrhagiae to amoxycillin, erythromycin, lincomycin, tetracycline, oxytetracycline and minocycline. LA - Eng MH - Amoxicillin/*pharmacology MH - Animal MH - Dogs MH - Erythromycin/*pharmacology MH - Leptospira interrogans/*drug effects MH - Lincomycin/*pharmacology MH - Microbial Sensitivity Tests MH - Minocycline/pharmacology MH - Oxytetracycline/pharmacology MH - Tetracycline/pharmacology MH - Tetracyclines/*pharmacology RN - 0 (Tetracyclines) RN - 10118-90-8 (Minocycline) RN - 114-07-8 (Erythromycin) RN - 154-21-2 (Lincomycin) RN - 26787-78-0 (Amoxicillin) RN - 60-54-8 (Tetracycline) RN - 79-57-2 (Oxytetracycline) PT - JOURNAL ARTICLE DA - 861118 DP - 1986 Jul IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 425-31 SB - M CY - GERMANY, WEST IP - 4 VI - 261 JC - Y55 AA - Author EM - 8701 AB - The failure of prophylactic penicillin to prevent a laboratory acquired case of Icterohaemorrhagiae leptospirosis prompted determination of the MIC and MBC of amoxycillin, erythromycin, lincomycin, tetracycline, oxytetracycline and minocycline for the infecting strain. Amoxycillin followed by erythromycin were the most effective, with MBCs of 0.5 mg/l after 7 days exposure and 0.1 mg/l after 21 days exposure respectively. Leptospires grew in the presence of high concentrations of tetracycline hydrochloride and oxytetracycline after prolonged incubation. This effect was less pronounced with minocycline, with MIC's of 0.025, 0.05 and 0.1 mg/l after 7, 14 and 21 days exposure respectively. The MIC of lincomycin was 0.25 mg/l at each time interval. These results support the high dose, long duration antibiotic regimens recommended in the literature. PMID- 3765950 CU - 92 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1986 Jul;261(4):425-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 86317628 AU - Bahaman AR AU - Marshall RB AU - Moriarty KM TI - Experimental trials on the use of radioimmunoassay for the detection of leptospiral antigens in urine. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Bacteriuria/diagnosis/immunology/*veterinary MH - Leptospira interrogans/immunology/*isolation & purification MH - Radioimmunoassay/veterinary MH - Weil's Disease/diagnosis/*veterinary RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 860929 DP - 1986 Jul IS - 0378-1135 TA - Vet Microbiol PG - 161-7 SB - M CY - NETHERLANDS IP - 2 VI - 12 JC - XBW AA - Author EM - 8612 AB - Trials were conducted on the use of the solid phase radioimmunoassay (RIA) to detect leptospires or their antigens in simulated urine samples. The procedure was relatively simple to perform and appeared to be specific in detecting certain numbers of leptospiral organisms or their antigens in experimentally prepared samples. With this technique, it was possible to examine individual or pooled urine samples for the presence of leptospires within half a day. This technique may be of value for the detection of leptospiruric animals if the sensitivity of the technique could be further increased. Suggestions for the improvement of the procedure are discussed. PMID- 3750817 CU - 91 SO - Vet Microbiol 1986 Jul;12(2):161-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 86293915 AU - Ellis WA AU - Thiermann AB TI - Isolation of Leptospira interrogans serovar bratislava from sows in Iowa. LA - Eng MH - Animal MH - Female MH - Iowa MH - Kidney/microbiology MH - Leptospira interrogans/growth & development/*isolation & purification MH - Swine MH - Swine Diseases/*microbiology MH - Uterus/microbiology MH - Weil's Disease/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 860916 DP - 1986 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1458-60 SB - M CY - UNITED STATES IP - 7 VI - 47 JC - 40C AA - Author EM - 8611 AB - Leptospira interrogans serovar bratislava was recovered from 2 of 10 sows examined from an Iowa slaughterhouse. Isolations were made from the kidney and genital tract of each sow. Serovar bratislava is not included in vaccines because it has not been previously isolated in the United States. PMID- 3740615 SO - Am J Vet Res 1986 Jul;47(7):1458-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 86282050 AU - Motie A AU - Myers DM AU - Storrs EE TI - A serologic survey for leptospires in nine-banded armadillos (Dasypus novemcinctus L.) in Florida. LA - Eng MH - Animal MH - Animals, Wild MH - Armadillos/*microbiology MH - Edentata/*microbiology MH - Female MH - Leptospira/*isolation & purification MH - Male MH - Serotyping MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE DA - 860917 DP - 1986 Jul IS - 0090-3558 TA - J Wildl Dis PG - 423-4 SB - M CY - UNITED STATES IP - 3 VI - 22 JC - KEM EM - 8611 PMID- 3735592 CU - 90 SO - J Wildl Dis 1986 Jul;22(3):423-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 86282033 AU - Fournier JS AU - Gordon JC AU - Dorn CR TI - Comparison of antibodies to Leptospira in white-tailed deer (Odocoileus virginianus) and cattle in Ohio. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle/*microbiology MH - Comparative Study MH - Deer/*microbiology MH - Leptospira/*immunology MH - Ohio MH - Species Specificity RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860917 DP - 1986 Jul IS - 0090-3558 TA - J Wildl Dis PG - 335-9 SB - M CY - UNITED STATES IP - 3 VI - 22 JC - KEM AA - Author EM - 8611 AB - A survey was conducted to determine the prevalence of leptospiral antibodies in sera from 248 white-tailed deer (Odocoileus virginianus) in Ohio. The sera were collected at check stations during the hunting season in 1983. The microscopic agglutination microtiter test was used to determine the presence of antibodies to Leptospira interrogans serovars pomona, icterohemorrhagiae, canicola, hardjo, and grippotyphosa. Eighteen of 248 (7.3%) serum samples had antibody titers (greater than or equal to 1:100) to at least one of the five serovars tested, with three of these samples reacting to more than one serovar. Prevalence did not differ significantly between sex or age groups. The serovar antigens reacting most frequently with serum antibodies were grippotyphosa (10 of 22, 45.5%) and pomona (eight of 22, 36.4%). Sera agglutinating with pomona antigen had higher titers (ranging from 1:200 to 1:6,400) than did sera agglutinating with the other serovars. These results were compared to results obtained from cattle tested at the Ohio Department of Agriculture Laboratories during 1983. There was a significant relationship between pomona infections detected in deer and cattle (P less than 0.05), but not with grippotyphosa. PMID- 3735579 CU - 91 SO - J Wildl Dis 1986 Jul;22(3):335-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 86298666 AU - Fu BY TI - [Nursing care of patients with disseminated pneumorrhagic leptospirosis] LA - Chi MH - Adolescence MH - Adult MH - Female MH - Hemorrhage/*nursing MH - Human MH - Leptospirosis/*nursing MH - Lung Diseases/*nursing MH - Male PT - JOURNAL ARTICLE DA - 861008 DP - 1986 Jul IS - 0254-1769 TA - Chung Hua Hu Li Tsa Chih PG - 163-4 SB - N CY - CHINA IP - 4 VI - 21 JC - CZR EM - 8612 PMID- 3638176 CU - 87 SO - Chung Hua Hu Li Tsa Chih 1986 Jul;21(4):163-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 87278472 AU - Mathur KN AU - Khanna VK AU - Purohit AK TI - Macroscopic plate agglutination results of serological examination of camels, cattle and goats for leptospirosis. LA - Eng MH - *Agglutination Tests MH - Animal MH - Camels/*microbiology MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Goats/*microbiology MH - Leptospirosis/diagnosis/*veterinary MH - Species Specificity PT - JOURNAL ARTICLE DA - 870921 DP - 1986 Jul-Sep IS - 0019-557X TA - Indian J Public Health PG - 170-2 CY - INDIA IP - 3 VI - 30 JC - GLN EM - 8711 PMID- 3610302 SO - Indian J Public Health 1986 Jul-Sep;30(3):170-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 87278471 AU - Ratnam S AU - Sundararaj T AU - Subramanian S TI - Role of bandicoots in human leptospirosis in Madras City. An epidemiological approach. LA - Eng MH - Animal MH - *Disease Vectors MH - Female MH - Human MH - India MH - Leptospira/isolation & purification MH - Leptospirosis/*transmission MH - Male MH - Rodentia/*microbiology PT - JOURNAL ARTICLE DA - 870921 DP - 1986 Jul-Sep IS - 0019-557X TA - Indian J Public Health PG - 167-9 CY - INDIA IP - 3 VI - 30 JC - GLN EM - 8711 PMID- 3610301 SO - Indian J Public Health 1986 Jul-Sep;30(3):167-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [23 medline neighbors] UI - 87021685 AU - Seguin B AU - Boucaud-Maitre Y AU - Quenin P AU - Lorgue G TI - [Epidemiologic evaluation of a sample of 91 rats (Rattus norvegicus) captured in the sewers of Lyon] LA - Fre MH - Animal MH - Bacterial Infections/epidemiology/transmission/*veterinary MH - Campylobacter fetus/isolation & purification MH - Campylobacter Infections/epidemiology/transmission MH - Carrier State/epidemiology/*veterinary MH - English Abstract MH - Female MH - France MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/epidemiology/veterinary MH - Male MH - Pasteurella/isolation & purification MH - Pasteurella Infections/epidemiology/veterinary MH - Rats/*microbiology MH - Rodent Diseases/*epidemiology MH - Salmonella typhimurium/immunology/isolation & purification MH - Salmonella Infections, Animal/epidemiology MH - Staphylococcal Infections/epidemiology/veterinary MH - Staphylococcus aureus/isolation & purification MH - Yersinia enterocolitica/isolation & purification MH - Yersinia Infections/epidemiology/veterinary PT - JOURNAL ARTICLE DA - 861118 DP - 1986 Jul IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 539-46 SB - M CY - GERMANY, WEST IP - 4 VI - 261 JC - Y55 AA - Author EM - 8701 AB - 91 rats captured in 1982 in the sewers of Lyon (France) have been examined for the presence of some microorganisms implicated in infections transmissible to man, by direct examination, bacteriological culture or detection of specific antibodies. Bacteriological results have shown a high proportion of carriers of Yersinia enterocolitica and frederiksenii (29%), of Pasteurella pneumotropica (29%), of Staphylococcus aureus (53%), and of Campylobacter jejuni (18%), a low proportion of carriers of Salmonella typhimurium (6%) and Leptospira (7%), and an absence of Listeria. Immunological reactions were often positive with Leptospira (21%), sometimes with Salmonella typhimurium, and always negative with Yersinia and Listeria. This work is a contribution to the knowledge of the health status of sewer rats considered to be an important public health risk as transmitters of anthropozoonoses. PMID- 3532637 CU - 90 TT - Bilan epidemiologique d'un echantillon de 91 rats (Rattus norvegicus) captures dans les egouts de Lyon. EA - A SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1986 Jul;261(4):539-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 87143959 AU - Tan DS AU - Abu Bakar Suleiman AU - Jeyaindran S TI - 16 cases of acute renal failure due to leptospirosis. LA - Eng MH - Adult MH - Human MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications MH - Malaysia MH - Middle Age MH - Peritoneal Dialysis MH - Prognosis PT - JOURNAL ARTICLE DA - 870409 DP - 1986 Jun IS - 0300-5283 TA - Med J Malaysia PG - 152-5 CY - MALAYSIA IP - 2 VI - 41 JC - M2M EM - 8706 PMID- 3821611 SO - Med J Malaysia 1986 Jun;41(2):152-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 87081208 AU - Teodori T AU - Gatti PL AU - Da Porto A AU - Bocci C AU - Amici G TI - [Leptospirosis] LA - Ita MH - Diagnosis, Differential MH - Disease Reservoirs MH - English Abstract MH - Human MH - *Leptospirosis/complications/diagnosis/etiology/therapy PT - JOURNAL ARTICLE DA - 870219 DP - 1986 Jun IS - 0017-0275 TA - G Clin Med PG - 159-64 CY - ITALY IP - 3 VI - 67 JC - FAP EM - 8704 PMID- 3792723 TT - La leptospirosi. EA - A SO - G Clin Med 1986 Jun;67(3):159-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [168 medline neighbors] UI - 87044668 AU - Riedemann S AU - Leal H AU - Zamora J TI - The first isolation of Leptospira interrogans serogroup Ballum serovar castellonis in Chile. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Pregnancy MH - Serotyping PT - JOURNAL ARTICLE DA - 861205 DP - 1986 Jun IS - 0514-7166 TA - Zentralbl Veterinarmed [B] PG - 393-4 CY - GERMANY, WEST IP - 5 VI - 33 JC - Y72 EM - 8702 PMID- 3776382 SO - Zentralbl Veterinarmed [B] 1986 Jun;33(5):393-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 87003829 AU - Li ZH TI - [Ischemic apoplexy in youth: clinical analysis and etiological study of 226 cases] LA - Chi MH - Adolescence MH - Adult MH - Atherosclerosis/complications MH - Cerebral Ischemia/*etiology MH - Cerebrovascular Disorders/*etiology MH - English Abstract MH - Female MH - Human MH - Hypertension/complications MH - Leptospirosis/complications MH - Male MH - Prognosis PT - JOURNAL ARTICLE DA - 861030 DP - 1986 Jun IS - 0412-4057 TA - Chung Hua Shen Ching Ching Shen Ko Tsa Chih PG - 146-8 CY - CHINA IP - 3 VI - 19 JC - D7Y EM - 8701 PMID- 3757628 CU - 90 EA - A SO - Chung Hua Shen Ching Ching Shen Ko Tsa Chih 1986 Jun;19(3):146-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 86318723 AU - Boroznov NI AU - Chernukha IuG AU - Amfiteatrova NF TI - [Effect of the viable cell count on the growth parameters of Leptospira cultures] LA - Rus MH - Cell Division MH - Culture Media MH - English Abstract MH - Leptospira/classification/*growth & development MH - Leptospira interrogans/classification/growth & development MH - Serotyping MH - Time Factors RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 861009 DP - 1986 Jun IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 33-5 SB - M CY - USSR IP - 6 JC - Y9O AA - Author EM - 8612 AB - The influence of the amount of live cells on the growth characteristics of 41 Leptospira pathogenic strains belonging to 4 serogroups at different stages of growth has been studied. The study has revealed that under the conditions of batch cultivation the maximum concentration of pathogenic leptospires in the inoculum decreases the duration of the lag phase and determines the highest specific growth rate characterizing the individual features of leptospires in the serogroups under study. PMID- 3751397 CU - 91 TT - Vliianie kolichestva zhiznesposobnykh kletok na parametry rosta kul'tur leptospir. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1986 Jun;(6):33-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 86298363 AU - Zhang ZF TI - [Role of macrophages and complement in protecting white mice against Leptospira icterohemorrhagiae infection] LA - Chi MH - Animal MH - Complement/*immunology MH - English Abstract MH - Female MH - Macrophages/*immunology MH - Male MH - Mice MH - Mice, Inbred BALB C MH - Mice, Nude MH - Weil's Disease/*immunology RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 861016 DP - 1986 Jun IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 153-6 CY - CHINA IP - 3 VI - 7 JC - CQG EM - 8612 PMID- 3742577 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1986 Jun;7(3):153-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 86290612 AU - Hogerzeil HV AU - Terpstra WJ AU - De Geus A AU - Korver H TI - Leptospirosis in rural Ghana. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Female MH - Ghana MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Occupational Diseases/*epidemiology MH - Risk MH - Rural Health MH - Weil's Disease/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860923 DP - 1986 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 162-6 SB - M CY - NETHERLANDS IP - 2 VI - 38 JC - WGJ AA - Author EM - 8611 AB - In a wet forest area of Ghana a serological survey of antibodies against 24 leptospira strains was carried out; 460 sera were obtained, of which 153 (33%) were positive. Bush farmers and cocoa plantation labourers showed 39% positive reactions and can be identified as high- risk groups. A reactivity rate of 14% was found among students, hospital staff and clerical occupations. No difference was observed between males and females, probably because both sexes are equally exposed. Cross-reactivity to different serovars was common. PMID- 3738982 CU - 91 SO - Trop Geogr Med 1986 Jun;38(2):162-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 86262388 AU - Franken P AU - Hartman EG AU - de Boer W TI - [Leptospira hardjo on a dairy farm] LA - Dut MH - Adult MH - Animal MH - Antibodies, Bacterial/isolation & purification MH - Case Report MH - Cattle/*microbiology MH - *Dairying MH - English Abstract MH - Female MH - Human MH - Leptospira/immunology/*isolation & purification MH - Leptospirosis/*diagnosis/microbiology MH - Male MH - Urine/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860731 DP - 1986 Jun 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 533-6 SB - M CY - NETHERLANDS IP - 11 VI - 111 JC - VRY AA - Author EM - 8610 AB - The results of a bacteriological and serological study of the presence of L. hardjo on a dairy farm in view of a case of milk fever in a farmer are reviewed. In addition, the epidemiology, prevention and possible treatment of the infection on the dairy farm are discussed. PMID- 3726853 CU - 91 TT - Leptospira hardjo op een melkveebedrijf. EA - A SO - Tijdschr Diergeneeskd 1986 Jun 1;111(11):533-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 86254278 AU - Waitkins SA AU - Hookey JV TI - The detection of leptospires by a chemiluminescent immunoassay. LA - Eng MH - Agglutination Tests MH - Animal MH - Immune Sera MH - Immunoassay/methods MH - Leptospira/*isolation & purification MH - Leptospira interrogans/immunology MH - Luminescence MH - Luminol/analogs & derivatives MH - Rabbits/immunology RN - 521-31-3 (Luminol) RN - 66612-29-1 (6-(N-(4-aminobutyl)-N-ethyl)amino-2,3-dihydrophthalazine- 1,4-dione) PT - JOURNAL ARTICLE DA - 860807 DP - 1986 Jun IS - 0022-2615 TA - J Med Microbiol PG - 353-6 SB - M CY - ENGLAND IP - 4 VI - 21 JC - J2N AA - Author EM - 8610 AB - Rabbit serum hyperimmune to Leptospira interrogans var icterohaemorrhagiae serovar icterohaemorrhagiae, reference strain RGA was conjugated to the chemiluminescent label ABEI (6-[N-(4-aminobutyl)- N-ethyl amino]-2,3-dihydrophthalazine-1,4-dione) in the presence of the coupling agent, EDC (1-ethyl-3(3-dimethyl amino-propyl)-carbodiimide HCl). The luminescent conjugate was incubated with homologous and heterologous antigens. The results indicate that chemiluminescence may provide an accurate and rapid method of detecting leptospires in biological fluids. PMID- 3723587 CU - 90 SO - J Med Microbiol 1986 Jun;21(4):353-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 87082624 AU - Anderson BS AU - Minette HP TI - Leptospirosis in Hawaii: shifting trends in exposure, 1907-1984. LA - Eng MH - Adult MH - Agricultural Workers' Diseases/*epidemiology/history/prevention & control MH - Animal MH - Disease Reservoirs MH - Female MH - Hawaii MH - History of Medicine, 20th Cent. MH - Human MH - Leptospirosis/*epidemiology/history/prevention & control/veterinary MH - Male MH - Middle Age MH - Mongoose MH - Rodent Diseases/epidemiology MH - Weil's Disease/*epidemiology/history/prevention & control PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 870127 DP - 1986 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 76-88 SB - M CY - TAIWAN IP - 2 VI - 13 JC - GTK AA - Author EM - 8704 AB - Leptospirosis was first recognized as an occupational disease of sugar plantation workers in Hawaii in 1907. Since then, shifts have been noted in the animal transmission cycles, the occupational groups at risk, and an increasing recognition of cases associated with avocational exposure. Surveys of the small mammal populations indicate rats, mice, and mongooses are the most important vectors in Hawaii. Serologic surveys of workers in high-risk occupations show antibody prevalence rates ranging from 12 to 82 percent. The epidemiology of leptospirosis in Hawaii is described, based on 182 cases reported to the Hawaii Department of Health from 1970-1984. The most common infecting serovar was mankarso in the Icterohaemorrhagiae serogroup; other serovars in the Icterohaemorrhagiae group were also frequently implicated as causing disease. The manifestations of disease noted by physicians in Hawaii are similar to those observed in the continental U.S. Fever, myalgia, and headache were the most common symptoms reported in the majority of cases in Hawaii; jaundice was noted in the records of 24 percent. Recommendations made to interrupt the cycle of transmission and reduce the chances of exposure in occupational settings include the control of rodent populations and vaccination of domestic animals. Personal hygiene among workers is to be encouraged, and the development of prophylactic measures is suggested either by immunization or by chemoprophylaxis. PMID- 3539849 CU - 90 SO - Int J Zoonoses 1986 Jun;13(2):76-88 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 86224551 AU - Oie S AU - Koshiro A AU - Konishi H AU - Yoshii Z TI - In vitro evaluation of combined usage of fosfomycin and 5-fluorouracil for selective isolation of Leptospira species. LA - Eng MH - Bacteriological Techniques MH - Culture Media MH - Evaluation Studies MH - Fluorouracil/*pharmacology MH - Fosfomycin/*pharmacology MH - Leptospira/drug effects/growth & development/*isolation & purification MH - Leptospira interrogans/drug effects/growth & development/*isolation & purification MH - Pseudomonas/drug effects RN - 0 (Culture Media) RN - 23155-02-4 (Fosfomycin) RN - 51-21-8 (Fluorouracil) PT - JOURNAL ARTICLE DA - 860627 DP - 1986 Jun IS - 0095-1137 TA - J Clin Microbiol PG - 1084-7 SB - M CY - UNITED STATES IP - 6 VI - 23 JC - HSH AA - Author EM - 8609 AB - The combined usage of fosfomycin (FOM) and 5-fluorouracil (5-FU) as selective agents for the isolation of leptospires from contaminated materials was investigated. Additive or synergistic antibacterial activity was apparent with the combination compared with each agent used separately. Of 54 bacterial strains tested, 52 were inhibited, while all 5 Leptospira strains tested were unaffected by the combined addition of FOM (400 micrograms/ml) and 5-FU (100 micrograms/ml) to Korthof medium. Furthermore, this combination successfully supported the selective growth of Leptospira interrogans serovar copenhageni in experimentally contaminated specimens. This FOM-5-FU combination is surmised to be useful for the selective isolation of leptospires from contaminated clinical, pathological, or environmental materials. PMID- 3519669 CU - 91 SO - J Clin Microbiol 1986 Jun;23(6):1084-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 87070055 AU - Tan DS AU - Dimitrakakis M AU - Zaini Rahman M AU - Fang R AU - Collett D AU - Ooi BG AU - Gust ID TI - Aetiology of acute hepatitis in Malaysia. LA - Eng MH - Acute Disease MH - Alanine Aminotransferase/blood MH - Aspartate Aminotransferase/blood MH - Cytomegalovirus Infections/etiology MH - Hepatitis/enzymology/*etiology MH - Hepatitis A/etiology MH - Hepatitis B/etiology MH - Hepatitis C/etiology MH - Human MH - Infectious Mononucleosis/etiology MH - Leptospirosis/etiology MH - Malaysia MH - Support, Non-U.S. Gov't RN - EC 2.6.1.1 (Aspartate Aminotransferase) RN - EC 2.6.1.2 (Alanine Aminotransferase) PT - JOURNAL ARTICLE DA - 870106 DP - 1986 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 205-8 SB - M CY - THAILAND IP - 2 VI - 17 JC - UVN AA - Author EM - 8703 AB - Icteric patients with clinical and biochemical evidence of liver disease, admitted into various hospitals in Malaysia, were investigated to determine the cause of their infection. Of these patients, 11.0% (16/145) were found positive for IgM anti-HAV (EIA), 4.1% (6/145) for IgM anti-HBc (EIA), 1.0% (1/102) for IgM anti-CMV (ELISA), 17.2% (16/64) for rising titres of leptospiral agglutinin, and none for heterophile antibody of EBV. Hepatitis NANB accounted for 67.9% of cases. The mean serum transaminases (ALT and AST) values in patients with hepatitis A and B were higher (more than 500IU) than in patients with leptospirosis or non-A, non-B hepatitis, whereas serum bilirubin levels were higher in patients with hepatitis A and leptospirosis than in patients with hepatitis B. PMID- 3024325 CU - 93 SO - Southeast Asian J Trop Med Public Health 1986 Jun;17(2):205-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [96 medline neighbors] UI - 86230262 AU - Looke DF TI - Weil's syndrome in a zoologist. LA - Eng MH - Adult MH - Animal MH - Australia MH - Case Report MH - Human MH - Leptospira interrogans/isolation & purification MH - Male MH - Mice/microbiology MH - *Occupational Diseases MH - Rats/microbiology MH - Weil's Disease/*epidemiology/microbiology/transmission MH - *Zoology PT - JOURNAL ARTICLE DA - 860707 DP - 1986 May 26 IS - 0025-729X TA - Med J Aust PG - 597, 600-1 SB - M SB - X CY - AUSTRALIA IP - 11 VI - 144 JC - M26 AA - Author EM - 8609 AB - Weil's syndrome is an unusual form of leptospirosis in Australia. A case of Weil's syndrome in a zoologist is described and an Australian native animal identified as the probable source of the infection. People who are in close contact with Australian native fauna should take precautions to minimize their exposure to leptospires. PMID- 3713590 CU - 88 SO - Med J Aust 1986 May 26;144(11):597, 600-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 86230253 AU - Hodgen AN AU - Stuckey MS TI - Leptospirosis in Western Australia, 1983-1984. LA - Eng MH - Agglutination Tests MH - Agricultural Workers' Diseases/epidemiology MH - Antibodies, Bacterial/analysis MH - Australia MH - Comparative Study MH - Human MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis/*epidemiology/immunology MH - Meat-Packing Industry MH - Microscopy MH - Occupational Diseases/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860707 DP - 1986 May 26 IS - 0025-729X TA - Med J Aust PG - 567-9 SB - M SB - X CY - AUSTRALIA IP - 11 VI - 144 JC - M26 AA - Author EM - 8609 AB - The diagnosis of leptospirosis is often difficult to make because of vague and mild symptoms. Patients who present with a "flu-like" illness and who have had either direct or indirect contact with infected animals should be investigated by serological examination. In Western Australia during 1983 and 1984, the sera of 937 patients were tested for the presence of leptospiral antibodies. Of these, 131 gave positive results; in 45, these were consistent with recently acquired infection. Apart from one veterinary worker, all the cases that were diagnosed serologically occurred in farmers and meatworkers. Farmers were most often infected with serovar hardjo. Meatworkers demonstrated a high degree of cross-reactivity among serovars pomona, hardjo, and to a lesser extent, icterohaemorrhagiae. However, in cases in which the infecting serovar was identifiable serologically, serovar pomona predominated. PMID- 3713585 CU - 91 SO - Med J Aust 1986 May 26;144(11):567-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 86230252 AU - Skilbeck NW AU - Miller GT TI - A serological survey of leptospirosis in Gippsland dairy farmers. LA - Eng MH - Adult MH - Agricultural Workers' Diseases/*epidemiology MH - Antibodies, Bacterial/analysis MH - Australia MH - Comparative Study MH - *Dairying MH - Female MH - Human MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Occupations MH - Risk MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860707 DP - 1986 May 26 IS - 0025-729X TA - Med J Aust PG - 565-7 SB - M SB - X CY - AUSTRALIA IP - 11 VI - 144 JC - M26 AA - Author EM - 8609 AB - Serological testing for leptospirosis was performed on sera from 1074 persons who were attending the 1983 Gippsland Field Days. The most common serological reactions were against representative serovars from serogroups Hebdomadis (12%), Panama (2%), Tarassovi (2%) and Pomona (1%). The reactions against serogroup Hebdomadis were attributed to exposure to serovar hardjo; the milking of dairy cows was found to be a major risk factor. The high prevalence of seropositive results among clinically normal dairy farmers highlights the need for caution in interpreting the results of laboratory testing for leptospirosis. PMID- 3713584 CU - 91 SO - Med J Aust 1986 May 26;144(11):565-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 86230249 AU - Faine S TI - Leptospirosis--still here [editorial] LA - Eng MH - Agricultural Workers' Diseases/epidemiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Australia MH - Bacterial Vaccines/administration & dosage MH - Cattle MH - Cattle Diseases/prevention & control MH - Female MH - Human MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology/immunology/veterinary MH - Male MH - Meat-Packing Industry MH - Occupational Diseases/epidemiology MH - Pregnancy MH - Zoonoses RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - EDITORIAL DA - 860707 DP - 1986 May 26 IS - 0025-729X TA - Med J Aust PG - 561 SB - M SB - X CY - AUSTRALIA IP - 11 VI - 144 JC - M26 EM - 8609 PMID- 3713581 CU - 91 SO - Med J Aust 1986 May 26;144(11):561 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 86263252 AU - Ellis WA AU - McParland PJ AU - Bryson DG AU - Cassells JA TI - Boars as carriers of leptospires of the Australis serogroup on farms with an abortion problem. LA - Eng MH - Abortion, Veterinary/etiology MH - Animal MH - Carrier State/*veterinary MH - Female MH - Leptospira/classification MH - Leptospirosis/transmission/*veterinary MH - Male MH - Pregnancy MH - Swine/*microbiology MH - Swine Diseases/*transmission PT - JOURNAL ARTICLE DA - 860725 DP - 1986 May 17 IS - 0042-4900 TA - Vet Rec PG - 563 SB - M CY - ENGLAND IP - 20 VI - 118 JC - XBS EM - 8610 PMID- 3727326 SO - Vet Rec 1986 May 17;118(20):563 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 86217055 AU - Waitkins SA TI - Leptospirosis in man, British Isles: 1984. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Great Britain MH - Human MH - Leptospirosis/*epidemiology MH - Middle Age MH - Occupational Diseases/*epidemiology MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 860722 DP - 1986 May 17 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 1324 SB - A SB - M SB - X CY - ENGLAND IP - 6531 VI - 292 JC - B4X EM - 8609 PMID- 3085831 CU - 91 SO - Br Med J (Clin Res Ed) 1986 May 17;292(6531):1324 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 86250286 AU - Quimby HH TI - Cutaneous histiocytosis vs leptospirosis [letter] LA - Eng MH - Animal MH - Diagnosis, Differential MH - Dog Diseases/diagnosis/*microbiology MH - Dogs MH - Leptospirosis/diagnosis/*veterinary MH - Reticuloendotheliosis/diagnosis/*veterinary MH - Skin Diseases/diagnosis/microbiology/*veterinary PT - LETTER DA - 860730 DP - 1986 May 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1142-3 SB - M CY - UNITED STATES IP - 10 VI - 188 JC - HAV EM - 8610 PMID- 3721961 CU - 91 SO - J Am Vet Med Assoc 1986 May 15;188(10):1142-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 86290634 AU - Motie A AU - Myers DM TI - Leptospirosis in sheep and goats in Guyana. LA - Eng MH - Animal MH - Comparative Study MH - *Goats MH - Guyana MH - Leptospirosis/epidemiology/*veterinary MH - Sheep MH - Sheep Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 860917 DP - 1986 May IS - 0049-4747 TA - Trop Anim Health Prod PG - 113-4 SB - M CY - SCOTLAND IP - 2 VI - 18 JC - WG2 EM - 8611 PMID- 3738995 CU - 88 SO - Trop Anim Health Prod 1986 May;18(2):113-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 87148723 AU - Alves VA AU - Yasuda PH AU - Yamashiro EH AU - Santos RT AU - Yamamoto LU AU - de Brito T TI - An immunohistochemic assay to localize leptospires in tissue specimens. LA - Eng MH - Animal MH - Guinea Pigs MH - *Immunoenzyme Techniques MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology PT - JOURNAL ARTICLE DA - 870403 DP - 1986 May-Jun IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 170-3 CY - BRAZIL IP - 3 VI - 28 JC - S9D EM - 8706 PMID- 3547599 CU - 90 SO - Rev Inst Med Trop Sao Paulo 1986 May-Jun;28(3):170-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 86194740 AU - Barbour AG AU - Hayes SF AU - Heiland RA AU - Schrumpf ME AU - Tessier SL TI - A Borrelia-specific monoclonal antibody binds to a flagellar epitope. LA - Eng MH - Antibodies, Bacterial/*immunology MH - Antibodies, Monoclonal/*immunology MH - Antigens, Bacterial/immunology MH - Bacterial Proteins/immunology MH - Borrelia/*immunology/ultrastructure MH - Flagella/immunology MH - Fluorescent Antibody Technique MH - Gold/diagnostic use MH - Microscopy, Electron MH - Molecular Weight MH - Support, U.S. Gov't, P.H.S. RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) RN - 7440-57-5 (Gold) PT - JOURNAL ARTICLE DA - 860528 DP - 1986 May IS - 0019-9567 TA - Infect Immun PG - 549-54 SB - M SB - X CY - UNITED STATES IP - 2 VI - 52 JC - GO7 AA - Author EM - 8608 AB - In immunofluorescence assays monoclonal antibody H9724 recognized eight species of the spirochetal genus Borrelia but not representatives of the genera Treponema, Leptospira, and Spirochaeta. We examined the reactivity of H9724 against subcellular components of Borrelia hermsii, an agent of relapsing fever, and B. burgdorferi, the cause of Lyme disease. H9724 bound to isolated periplasmic flagella of the two borreliae. In Western blots the antibody reacted with the predominant protein in flagellar preparations from B. hermsii and B. burgdorferi; the apparent molecular weights of these flagellins were 39,000 and 41,000, respectively. PMID- 3516878 CU - 91 SO - Infect Immun 1986 May;52(2):549-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 86263216 AU - Sebek J TI - [Relation between the incidence of antibodies against Leptospira interrogans in working dogs and in free-living small mammals] LA - Cze MH - Animal MH - Antibodies, Bacterial/analysis MH - Czechoslovakia MH - Dogs/*microbiology MH - English Abstract MH - Leptospira interrogans/*immunology MH - Rodentia/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860725 DP - 1986 May IS - 0375-8427 TA - Vet Med (Praha) PG - 295-306 SB - M CY - CZECHOSLOVAKIA IP - 5 VI - 31 JC - XBP AA - Author EM - 8610 AB - Three localities were chosen in the borderland of the South Bohemian Region to investigate the problems and relations (if there are any) between the incidence of antibodies to Leptospira interrogans (L. i.) in wild ground small mammals and dogs moving in the same environment. In these regions, service dogs work as border guards every day. Blood samples of dogs at these localities were taken at about three-month intervals (from the June 1982 to the October 1984) to investigate the antibodies to L. i. serovars. Parallelly, wild ground small mammals and wild birds were caught at the same localities to be subject to the same examinations. A close relationship between the incidence of L. i. antibodies in ground small mammals and in service dogs was demonstrated at all three localities. At localities no. 1 and 2, the serovar grippotyphosa was found to be dominant in service dogs, which was also found in small rodents. On the other hand, the serovar icterohaemorrhagiae dominated in service dogs at locality no. 3. When changes in the incidence of L. i. antibodies were studied in service dogs and in wild small mammals, the peak of incidence at localities 1 and 2 was in the other half of the year; this relates to the usual maximum incidence in the natural reservoir of the serovar grippotyphosa, i.e. in rodents. On the contrary, at the third locality the peak of incidence of L. i. antibodies was recorded in the winter 1983-1984.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 3088801 CU - 91 TT - Vztah mezi vyskytem protilatek proti Leptospira interrogans u sluzebnich psu a u volne zijicich drobnych zemnich savcu. EA - A SO - Vet Med (Praha) 1986 May;31(5):295-306 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 86236978 AU - McKeown JD AU - Ellis WA TI - Leptospira hardjo agalactia in sheep. LA - Eng MH - Animal MH - Cattle MH - Female MH - Lactation Disorders/etiology/*veterinary MH - Leptospira/*isolation & purification MH - Leptospirosis/complications/*veterinary MH - Milk/microbiology MH - Pregnancy MH - Sheep MH - Sheep Diseases/blood/*etiology/physiopathology PT - JOURNAL ARTICLE DA - 860715 DP - 1986 Apr 26 IS - 0042-4900 TA - Vet Rec PG - 482 SB - M CY - ENGLAND IP - 17 VI - 118 JC - XBS EM - 8609 PMID- 3716127 SO - Vet Rec 1986 Apr 26;118(17):482 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 86184931 AU - Le Febvre RB AU - Thiermann AB TI - DNA homology studies of leptospires of serogroups Sejroe and Pomona from cattle and swine. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Comparative Study MH - DNA, Bacterial/*genetics/isolation & purification MH - Leptospira interrogans/classification/*genetics MH - Nucleic Acid Hybridization MH - Sequence Homology, Nucleic Acid MH - Serotyping MH - Species Specificity MH - Swine MH - Swine Diseases/*microbiology MH - Weil's Disease/microbiology/*veterinary RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 860516 DP - 1986 Apr IS - 0002-9645 TA - Am J Vet Res PG - 959-63 SB - M CY - UNITED STATES IP - 4 VI - 47 JC - 40C AA - Author EM - 8607 AB - Hybridization studies of chromosomal DNA from leptospiral strains representing Leptospira interrogans, serogroups Sejroe and Pomona from cattle and swine were performed to determine the degree of homology among their DNA sequences. Chromosomal DNA isolated from leptospires of the Sejroe and Pomona serogroups was radiolabeled and used to probe DNA isolated from other strains in these serogroups. Serovars hardjo (hardjoprajitno), hardjo (hardjo-bovis), balcanica (1627 Burgas), pomona (pomona), and kennewicki (LT-1026) were probed to determine the degree of homology among their chromosomes. Serovars pomona and kennewicki were homologous to each other. They also had a high degree of homology with hardjo (hardjoprajitno) and, to a lesser extent, with hardjo (hardjo-bovis) strains. However, hardjoprajitno and hardjo-bovis had little homology to each other. Serovar balcanica had a high degree of homology with hardjo-bovis isolates, but little homology with hardjoprajitno. Although serologically indistinguishable, the reference strain hardjoprajitno was genetically dissimilar to hardjo-bovis strains isolated from North American cattle. PMID- 3963602 CU - 91 SO - Am J Vet Res 1986 Apr;47(4):959-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 87119565 AU - Thompson L AU - Hassi M AU - Haenseler I AU - Awad C TI - [Weil's syndrome caused by Leptospira interrogans serogroup australis serotype bratislava] LA - Spa MH - Case Report MH - English Abstract MH - Human MH - Leptospira/classification MH - Male MH - Middle Age MH - Serodiagnosis MH - Weil's Disease/*diagnosis/microbiology PT - JOURNAL ARTICLE DA - 870323 DP - 1986 Apr IS - 0034-9887 TA - Rev Med Chil PG - 346-8 CY - CHILE IP - 4 VI - 114 JC - SHD EM - 8705 PMID- 3809808 TT - Sindrome de Weil por Leptospira interrogans serogrupo Australis serotipo bratislava. EA - A SO - Rev Med Chil 1986 Apr;114(4):346-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 87099300 AU - Nicolescu M AU - Andreescu N AU - Sosin A TI - Data about human leptospirosis in Romania (1978-1984) obtained in the Cantacuzino Institute. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Leptospira/classification MH - Leptospirosis/*epidemiology/transmission MH - Male MH - Romania MH - Water Microbiology MH - Weil's Disease/*epidemiology/transmission PT - JOURNAL ARTICLE DA - 870128 DP - 1986 Apr-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 109-15 CY - ROMANIA IP - 2 VI - 45 JC - 8EM EM - 8704 PMID- 3800629 CU - 88 SO - Arch Roum Pathol Exp Microbiol 1986 Apr-Jun;45(2):109-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 87010538 AU - Cinco M AU - Banfi E AU - Panfili E TI - Heterogeneity of lipopolysaccharide banding patterns in Leptospira spp. LA - Eng MH - Electrophoresis, Polyacrylamide Gel MH - Leptospira/*analysis/classification MH - Lipopolysaccharides/*analysis MH - Support, Non-U.S. Gov't RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 861031 DP - 1986 Apr IS - 0022-1287 TA - J Gen Microbiol PG - 1135-8 SB - M CY - ENGLAND VI - 132 ( Pt 4) JC - I87 AA - Author EM - 8701 AB - Strains of Leptospira interrogans and Leptospira biflexa, examined by electrophoresis after whole cell lysis and protein digestion, revealed the presence of 2-keto-3-deoxyoctonate and an heterogeneous lipopolysaccharide electrophoretic banding pattern, which was characteristic of the species. PMID- 3760822 CU - 91 SO - J Gen Microbiol 1986 Apr;132 ( Pt 4):1135-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 86255280 AU - Khaimzon BI AU - Maksimenko GN TI - [Protracted course of polymyositis in leptospirosis in a patient with chronic opisthorchiasis] LA - Rus MH - Adult MH - Case Report MH - Chronic Disease MH - Human MH - Kidney Failure, Acute/etiology/pathology MH - Leptospirosis/*complications/pathology MH - Male MH - Myositis/*etiology/pathology MH - Opisthorchiasis/*complications/pathology PT - JOURNAL ARTICLE DA - 860725 DP - 1986 Apr IS - 0023-2149 TA - Klin Med (Mosk) PG - 131-3 CY - USSR IP - 4 VI - 64 JC - KW2 EM - 8610 PMID- 3724008 TT - Dlitel'noe techenie polimiozita pri leptospiroze u bol'nogo khronicheskim opistorkhozom. SO - Klin Med (Mosk) 1986 Apr;64(4):131-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 86255279 AU - Primachenko NB AU - Beliak GM AU - Biriukov IS TI - [Rare complication in leptospirosis] LA - Rus MH - Acute Disease MH - Adult MH - Case Report MH - Human MH - Male MH - Pancreatitis/*etiology/pathology MH - Pericarditis/*etiology/pathology MH - Weil's Disease/*complications/pathology PT - JOURNAL ARTICLE DA - 860725 DP - 1986 Apr IS - 0023-2149 TA - Klin Med (Mosk) PG - 129-31 CY - USSR IP - 4 VI - 64 JC - KW2 EM - 8610 PMID- 3724007 TT - Redkoe oslozhnenie pri leptospiroze. SO - Klin Med (Mosk) 1986 Apr;64(4):129-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 86237337 AU - Lutsik BD AU - Mostiuk AI AU - Titov VM AU - Pastrik NS TI - [Leptospirosis in the western regions of the Ukrainian S.S.R.] LA - Rus MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Ukraine PT - JOURNAL ARTICLE DA - 860715 DP - 1986 Apr IS - 0049-6804 TA - Vrach Delo PG - 99-101 CY - USSR IP - 4 JC - XLS EM - 8609 PMID- 3716356 CU - 88 TT - Leptospiroz v zapadnykh oblastiakh Ukrainskoi SSR. EA - A SO - Vrach Delo 1986 Apr;(4):99-101 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 86237297 AU - Asauliuk IK AU - Lukavyi AD TI - [Clinical features of the course and treatment of leptospirosis] LA - Rus MH - Human MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 860715 DP - 1986 Apr IS - 0049-6804 TA - Vrach Delo PG - 108-10 CY - USSR IP - 4 JC - XLS EM - 8609 PMID- 3716325 TT - Klinicheskie osobennosti techeniia i terapiia bol'nykh leptospirozom. SO - Vrach Delo 1986 Apr;(4):108-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 86237296 AU - Gazhiev VV AU - Bondarev LS AU - Anishchenko GA TI - [Epidemiologic features and clinical characteristics of leptospirosis in miners] LA - Rus MH - Animal MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - *Mining MH - Occupational Diseases/*epidemiology MH - Rats MH - Rodent Diseases/epidemiology MH - Ukraine PT - JOURNAL ARTICLE DA - 860715 DP - 1986 Apr IS - 0049-6804 TA - Vrach Delo PG - 105-8 CY - USSR IP - 4 JC - XLS EM - 8609 PMID- 3716324 CU - 88 TT - Epidemiologicheskie osobennosti i klinicheskaia kharakteristika leptospiroza u shakhterov. EA - A SO - Vrach Delo 1986 Apr;(4):105-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 86237295 AU - Frolov AF AU - Pletnev VM AU - Lenartovich LS AU - Nikolaev VG AU - Butylin VIu TI - [Complex use of methods of sorption detoxication in the treatment of leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Aged MH - English Abstract MH - Female MH - Hemoperfusion MH - Human MH - Leptospirosis/*therapy MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 860715 DP - 1986 Apr IS - 0049-6804 TA - Vrach Delo PG - 102-5 CY - USSR IP - 4 JC - XLS EM - 8609 PMID- 3716323 TT - Kompleksnoe primenenie metodov sorbtsionnoi detoksikatsii v terapii leptospiroza. EA - A SO - Vrach Delo 1986 Apr;(4):102-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [77 medline neighbors] UI - 86215966 AU - Williams WR AU - Davies BH TI - Pseudo-leptospires in broncho-alveolar lavage fluid and blood cell cultures. LA - Eng MH - Blood Platelets/*microbiology/pathology MH - Body Fluids/cytology/*microbiology MH - Bronchi/*microbiology/pathology MH - Cells, Cultured MH - Cilia MH - Diagnosis, Differential MH - Epithelium/pathology MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/diagnosis MH - Male MH - Platelet Aggregation MH - Pulmonary Alveoli/*microbiology/pathology MH - Sarcoidosis/pathology PT - JOURNAL ARTICLE DA - 860627 DP - 1986 Apr IS - 0007-1021 TA - Br J Exp Pathol PG - 167-70 SB - M CY - ENGLAND IP - 2 VI - 67 JC - AWW AA - Author EM - 8609 AB - Two types of microscopic filaments were observed in mucous and fluid obtained by broncho-alveolar lavage (BAL). Filaments in mucous smears were probably cilia from desquamated ciliated epithelial cells. Those in BAL fluid, resembling leptospira, may originate from platelets as similar filaments were produced in vitro by exposing platelets to thrombin. PMID- 3707849 SO - Br J Exp Pathol 1986 Apr;67(2):167-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 86227862 AU - Magnarelli LA AU - Anderson JF AU - Apperson CS AU - Fish D AU - Johnson RC AU - Chappell WA TI - Spirochetes in ticks and antibodies to Borrelia burgdorferi in white- tailed deer from Connecticut, New York State, and North Carolina. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Borrelia/*immunology MH - Connecticut MH - Deer/*microbiology/parasitology MH - Dogs MH - Female MH - Fluorescent Antibody Technique MH - Male MH - New York MH - North Carolina MH - Seasons MH - Ticks/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860722 DP - 1986 Apr IS - 0090-3558 TA - J Wildl Dis PG - 178-88 SB - M CY - UNITED STATES IP - 2 VI - 22 JC - KEM AA - Author EM - 8609 AB - Ticks were screened for spirochetes and serum samples from white-tailed deer (Odocoileus virginianus) were assayed for antibodies to Borrelia burgdorferi during 1983-1984. Using fluorescein isothiocyanate-labeled rabbit antibodies produced to B. burgdorferi, the etiologic agent of Lyme disease, spirochetes were detected in Ixodes dammini (10.5% of 1,193) and Dermacentor albipictus (0.6% of 157) adults from Connecticut, I. dammini nymphs (49.1% of 108) and adults (64.7% of 99) from Armonk, New York, and in I. scapularis (0.4% of 531) and Amblyomma americanum (3.5% of 173) adults from North Carolina. Infected ticks were either seeking hosts or feeding on deer during the summer and fall. Direct fluorescent antibody staining also revealed spirochetes in two larvae of I. scapularis that emerged from eggs deposited by separate females in the laboratory. Using indirect immunofluorescence tests, antibodies to B. burgdorferi were identified in white-tailed deer living in tick-infested areas of all three states. Aside from minor cross-reactivity, there was no serologic evidence of Treponema or Leptospira infections. Ixodes dammini is a primary vector of B. burgdorferi in northeastern United States, but in North Carolina, other ixodid ticks may transmit this spirochete to humans and wildlife. PMID- 3520030 CU - 91 SO - J Wildl Dis 1986 Apr;22(2):178-88 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 87069510 AU - Galli M AU - Invernizzi F AU - Chemotti M AU - Monti G AU - Gasparro MG AU - Caredda F AU - Negri C AU - Moroni M TI - Cryoglobulins and infectious diseases. LA - Eng MH - Acquired Immunodeficiency Syndrome/blood MH - Antigen-Antibody Complex/analysis MH - AIDS-Related Complex/blood MH - Cryoglobulinemia/classification/diagnosis/immunology/physiopathology MH - Cryoglobulins/*analysis/metabolism MH - Hepatitis A/*blood MH - Hepatitis B/*blood MH - Hepatitis B Surface Antigens/immunology MH - Hepatitis C/blood MH - Human MH - Male MH - Precipitation RN - 0 (Antigen-Antibody Complex) RN - 0 (Cryoglobulins) RN - 0 (Hepatitis B Surface Antigens) PT - JOURNAL ARTICLE DA - 870107 DP - 1986 Apr-Jun IS - 0390-5748 TA - Ric Clin Lab PG - 301-13 SB - M CY - ITALY IP - 2 VI - 16 JC - TEA AA - Author EM - 8703 AB - The relationship between infectious diseases due to various pathogenetic factors and cryoglobulin production mechanisms has been investigated. Cryoglobulins have been evidenced in infections caused by very heterogeneous pathogens, i.e. leptospirosis, psittacosis, Mediterranean tick typhus, brucellosis, gram-negative bacterial septicemias, in which they had never been previously reported. In type A hepatitis a high cryoglobulin prevalence (91%) has been confirmed during the acute phase, with a rapid decrease both in prevalence and concentration in the subsequent stages of the disease. Cryoglobulins were all of type III and were mainly represented by IgM; anti-HAV-IgM antibodies have been evidenced in all but one cryoprecipitates. In non- A, non-B hepatitis a lower cryoglobulin prevalence (44.7%) was shown during the acute phase and the same fast decrease has been noted in the subsequent stages. Cryoglobulins were all of type III and in some cases polyclonal IgG was the only Ig class present in cryoprecipitates. The cryoglobulin prevalence in the acute phase of HBsAg-positive hepatitis amounted to 73.4%; all the cryoprecipitates were of type III. No correlation between the presence of cryoglobulins and HBeAg positivity or between cryoglobulins and delta agent infections was found. In all the cases studied the presence of cryoglobulins was related to the persistence of liver damage. Cryoglobulins were not found in HBsAg chronic carriers, while they have been evidenced, by a preliminary study, in 41.6% of HTLV-III antibody-positive subjects complaining of a persistent generalized lymphadenopathy without clinical or laboratory signs of liver impairment. No HTLV-III antibodies were found by ELISA method in the type III cryoprecipitates. PMID- 3097790 CU - 92 SO - Ric Clin Lab 1986 Apr-Jun;16(2):301-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 86209792 AU - Ellis WA AU - Cassells JA AU - Doyle J TI - Genital leptospirosis in bulls. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/microbiology/*transmission MH - Female MH - Genital Diseases, Male/microbiology/transmission/*veterinary MH - Genitalia, Male/microbiology MH - Kidney/microbiology MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/microbiology/transmission/*veterinary MH - Male MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 860602 DP - 1986 Mar 22 IS - 0042-4900 TA - Vet Rec PG - 333 SB - M CY - ENGLAND IP - 12 VI - 118 JC - XBS EM - 8608 PMID- 3705372 SO - Vet Rec 1986 Mar 22;118(12):333 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 86209770 AU - Ellis WA AU - McParland PJ AU - Bryson DG AU - Thiermann AB AU - Montgomery J TI - Isolation of leptospires from the genital tract and kidneys of aborted sows. LA - Eng MH - Abortion, Veterinary/etiology/*microbiology MH - Animal MH - Fallopian Tubes/microbiology MH - Female MH - Genitalia, Female/*microbiology MH - Kidney/*microbiology MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*microbiology MH - Uterus/microbiology PT - JOURNAL ARTICLE DA - 860602 DP - 1986 Mar 15 IS - 0042-4900 TA - Vet Rec PG - 294-5 SB - M CY - ENGLAND IP - 11 VI - 118 JC - XBS AA - Author EM - 8608 AB - Twenty sows were examined as part of an investigation into the relative importance of the genital and urinary tracts as sites of leptospiral persistence in pigs. The sows had previously either aborted leptospire- infected fetuses or aborted on farms where leptospire infection had been demonstrated in other litters. Leptospires belonging to the Australis serogroup were recovered from the upper genital tract of all the sows. In contrast, leptospires were only recovered from 75 per cent of their kidneys. Isolates from 10 of the sows were identified to serovar level: six were serovar muenchen and four were bratislava. Persistence was observed in renal and genital tissues for up to 147 days after abortion. PMID- 3705357 SO - Vet Rec 1986 Mar 15;118(11):294-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 86156470 AU - Edwards CN AU - Nicholson GD AU - Hassell TA AU - Everard CO AU - Callender J TI - Thrombocytopenia in leptospirosis: the absence of evidence for disseminated intravascular coagulation. LA - Eng MH - Adult MH - Alanine Aminotransferase/blood MH - Disseminated Intravascular Coagulation/etiology/*parasitology MH - Female MH - Fibrinogen/metabolism MH - Human MH - Kupffer Cells/metabolism MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Platelet Count MH - Prospective Studies MH - Support, Non-U.S. Gov't MH - Thrombocytopenia/etiology/*parasitology RN - EC 2.6.1.2 (Alanine Aminotransferase) RN - 9001-32-5 (Fibrinogen) PT - JOURNAL ARTICLE DA - 860424 DP - 1986 Mar IS - 0002-9637 TA - Am J Trop Med Hyg PG - 352-4 SB - A SB - M CY - UNITED STATES IP - 2 VI - 35 JC - 3ZQ AA - Author EM - 8606 AB - In a prospective study of human leptospirosis, thrombocytopenia was demonstrated in 54% of 24 cases. The only additional laboratory evidence suggestive of disseminated intravascular coagulation lay in a mild elevation of fibrinogen degradation products, but this occurred with equal frequency in nonthrombocytopenic patients. There is therefore no causal relationship between disseminated intravascular coagulation and the thrombocytopenia of human leptospirosis. PMID- 3953949 SO - Am J Trop Med Hyg 1986 Mar;35(2):352-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 87107547 AU - Ye DN AU - Wang CX AU - Yan RH AU - Zhao SM AU - Dai BM TI - [SPA-ELISA in the detection of leptospiral antibodies in the sera of leptospirosis patients] LA - Chi MH - Antibodies, Bacterial/*analysis MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Leptospira interrogans/*immunology MH - Staphylococcal Protein A MH - Weil's Disease/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870316 DP - 1986 Mar IS - 0257-7712 TA - Hua Hsi I Ko Ta Hsueh Hsueh Pao PG - 17-9 CY - CHINA IP - 1 VI - 17 JC - GEB EM - 8705 PMID- 3804303 CU - 91 EA - A SO - Hua Hsi I Ko Ta Hsueh Hsueh Pao 1986 Mar;17(1):17-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 87030803 AU - Crevatin D AU - Banfi E AU - Crotti D AU - Ruaro E AU - Cinco M TI - Serosurvey on the presence of leptospiral agglutinins in humans in Northern Italy. LA - Eng MH - Agglutination Tests MH - Agglutinins/*analysis MH - Antibodies, Bacterial/*analysis MH - Human MH - Italy MH - Leptospira/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology/immunology MH - Occupational Diseases/epidemiology/immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/epidemiology/immunology RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 861216 DP - 1986 Mar IS - 0392-2990 TA - Eur J Epidemiol PG - 44-7 SB - M CY - ITALY IP - 1 VI - 2 JC - ERE AA - Author EM - 8702 AB - The article reports data concerning a serosurvey carried out in the province of Gorizia as a part of a research project sponsored by the National Research Council (CNR) on the epidemiological status of leptospirosis in Northern Italy. Microagglutination tests have been carried out on sera taken from randomly chosen healthy people and from humans exposed to occupational hazards, at a representing sample size for each category. The results have shown 8.29% agglutinin prevalence in healthy people, serovars bratislava, sejroe and canicola being predominant. Prevalence agglutinin rates were higher in meat workers (11.76%), sweepers (16.66%) and breeders (40%); in the latter category antibodies to Leptospira hardjo have been found out; this is the first reported instance of human contamination by L. hardjo in Italy. PMID- 3770149 CU - 91 SO - Eur J Epidemiol 1986 Mar;2(1):44-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 86168787 AU - Rule PL AU - Alexander AD TI - Gellan gum as a substitute for agar in leptospiral media. LA - Eng MH - Agar MH - Animal MH - Comparative Study MH - *Culture Media MH - Hamsters MH - Kidney/microbiology MH - Leptospira/*growth & development/isolation & purification MH - Leptospira interrogans/*growth & development/immunology/pathogenicity MH - Liver/microbiology MH - Polysaccharides/metabolism MH - *Polysaccharides, Bacterial MH - Polysorbates MH - Septicemia MH - Virulence MH - Weil's Disease/microbiology RN - 0 (Culture Media) RN - 0 (Polysaccharides) RN - 0 (Polysaccharides, Bacterial) RN - 0 (Polysorbates) RN - 71010-52-1 (gellan gum) RN - 9002-18-0 (Agar) PT - JOURNAL ARTICLE DA - 860514 DP - 1986 Mar IS - 0095-1137 TA - J Clin Microbiol PG - 500-4 SB - M CY - UNITED STATES IP - 3 VI - 23 JC - HSH AA - Author EM - 8607 AB - An albumin polysorbate semisolid medium (Ellinghausen McCullough Johnson Harris medium) gelled with gellan gum (Gelrite; Kelco Div., Merck & Co., Inc.) compared favorably with conventional agar media for the cultivation of both pathogenic and saprophytic leptospires. The gellan gum medium supported the growth of all 18 leptospiral strains studied which included an array of serovars with various fastidious growth characteristics. Gellan gum medium was also used advantageously as a long-term maintenance medium; 9- to 12-month-old cultures still contained viable organisms. The colonial growth in gellan gum plating medium of six representative strains was consistent with previously described colonial growth on agar plating media. In addition, gellan gum medium appeared to be an excellent medium for the recovery of leptospires from the blood, liver, and kidneys of hamsters experimentally infected with a virulent Leptospira interrogans serovar bataviae strain. As few as 1 to 10 organisms in the infective tissue could be recovered in semisolid Ellinghausen McCullough Johnson Harris- gellan gum medium. The antigenicity did not appear to be affected by growth in gellan gum medium. The hamster-virulent strain of L. interrogans serovar bataviae isolated from a moribund hamster maintained its virulence after 10 sequential passages in gellan gum medium. Gellan gum medium can be a valuable adjunct to currently used cultural procedures. PMID- 3754265 CU - 92 SO - J Clin Microbiol 1986 Mar;23(3):500-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 86291100 AU - Thompson JC AU - Marshall RB TI - In vitro studies of haemolysis by Leptospira interrogans serovars pomona and ballum. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/blood/microbiology MH - Hamsters MH - *Hemolysis MH - Human MH - In Vitro MH - Leptospira interrogans/*metabolism MH - Plasma/physiology MH - Support, Non-U.S. Gov't MH - Weil's Disease/blood/microbiology/veterinary PT - JOURNAL ARTICLE DA - 860916 DP - 1986 Mar IS - 0378-1135 TA - Vet Microbiol PG - 285-92 SB - M CY - NETHERLANDS IP - 3 VI - 11 JC - XBW AA - Author EM - 8611 AB - Washed and unwashed red blood cells (RBC) from young calves, adult cattle, hamsters and humans were incubated with Leptospira interrogans serovars pomona and ballum. Washed cells suspended in saline were always haemolysed while unwashed cells and those which were washed and resuspended in plasma were never haemolysed, despite the presence of large numbers of organisms within the culture supernatant. Pomona produced greater haemolysis of cattle and human RBC than did ballum, but with hamster RBC ballum produced greater haemolysis than did pomona. A group of 6- to 9-month-old cattle infected with pomona showed no signs of clinical disease and RBC taken from them before infection and during the development of antibodies to pomona were haemolysed by pomona only after the cells were washed. Plasma therefore appears to have a protective function. This in vitro protective function of plasma even extended to plasma from young seronegative calves. PMID- 3739212 SO - Vet Microbiol 1986 Mar;11(3):285-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 86289691 AU - Basaca-Sevilla V AU - Cross JH AU - Pastrana E TI - Leptospirosis in the Philippines. LA - Eng MH - Animal MH - Buffaloes/microbiology MH - Cattle/microbiology MH - Dogs/microbiology MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Philippines MH - Prisoners MH - Rats/microbiology MH - Serodiagnosis MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 860917 DP - 1986 Mar IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 71-4 SB - M CY - THAILAND IP - 1 VI - 17 JC - UVN AA - Author EM - 8611 AB - Leptospirosis was first isolated in the Philippines from one of the human cases of Weil's Disease in 1932 and from then up to 1970 a total of 65 cases were studied sporadically. From 1971 up to 1973 a total of 390 cases were studied out of which 82 (21.02%) were found positive by isolation and serological examination. An outbreak of leptospirosis was followed up from 1976 to 1983 in a penal farm in Sablayan, Mindoro. At the time of the outbreak, 31% of the sera from patients and those with complaints reacted to one or more antigen pools with 40% of these reactors reacting to only one antigen pool. Only one percent of prisoners and residents without complaints reacted to one or more antigen pools, with 80% of these reactors reacting to pool 3 alone. Three and half years later, a first follow-up was done in which 9.07% reacted to one or more pools. Of these, 42% reacted to pool 2 and 82% to pool 3 alone or in combination with other pool. Ninety five percent of those reacting to Pool 2 reacted to L. pyrogenes and 88% of those that reacted to Pool 3 reacted to L. autumnalis. More than three years later after the first follow-up, a second follow up was done. This time 2.29% reacted to one or more pools. Most reacted specifically to L. autumnalis. The residents outside the penal farm were all non-reactive. Sampling from another penal colony and in four agricultural areas revealed no significant reactivity.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 3738610 CU - 88 SO - Southeast Asian J Trop Med Public Health 1986 Mar;17(1):71-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 86291101 AU - Ellis WA AU - O'Brien JJ AU - Neill SD AU - Bryson DG TI - Bovine leptospirosis: experimental serovar hardjo infection. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Fetal Diseases/microbiology/*veterinary MH - Fluorescent Antibody Technique MH - Leptospira interrogans/immunology/isolation & purification MH - Placenta/microbiology MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/*veterinary MH - Weil's Disease/microbiology/transmission/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860916 DP - 1986 Mar IS - 0378-1135 TA - Vet Microbiol PG - 293-9 SB - M CY - NETHERLANDS IP - 3 VI - 11 JC - XBW AA - Author EM - 8611 AB - Almost the full range of clinical signs observed in pregnant cattle naturally infected with Leptospira interrogans serovar hardjo was observed in this experimental study in which 22 heifers were infected by intraplacentome inoculation with serovar hardjo strains. These features included abortion, mummification, stillbirth, premature and term birth of weak calves and full-term birth of live apparently healthy calves. Leptospires were demonstrated in all but three calves by culture and or immunofluorescence. PMID- 3526704 CU - 91 SO - Vet Microbiol 1986 Mar;11(3):293-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 86230358 AU - Kovalevskii IuV AU - Korenberg EI TI - [Natural foci of human diseases near the Baikal and Amur railroad mainline (a review of research)] LA - Rus MH - Animal MH - Arachnid Vectors MH - Bacterial Infections/*epidemiology MH - *Disease Reservoirs MH - Disease Vectors MH - Encephalitis, Tick-Borne/epidemiology MH - Environmental Microbiology MH - Human MH - Leptospirosis/epidemiology MH - Rabies/epidemiology MH - *Railroads MH - Rickettsia Infections/epidemiology MH - Siberia MH - Ticks MH - Tularemia/epidemiology MH - Virus Diseases/*epidemiology MH - Yersinia Infections/epidemiology PT - JOURNAL ARTICLE PT - REVIEW DA - 860707 DP - 1986 Mar-Apr IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 71-5 CY - USSR IP - 2 JC - M72 EM - 8609 RF - 42 PMID- 3520274 CU - 90 TT - Prirodnye ochagi boleznei cheloveka v zone Baikalo-Amurskoi zheleznodorozhnoi magistrali (obzor issledovanii). SO - Med Parazitol (Mosk) 1986 Mar-Apr;(2):71-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 86132878 AU - Long GG TI - Examination of the porcine fetus. LA - Eng MH - Abortion, Veterinary/*pathology MH - Animal MH - Autopsy/*veterinary MH - Bacterial Infections/veterinary MH - Female MH - Fetus/pathology MH - Leptospirosis/veterinary MH - Parvoviridae Infections/veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*pathology PT - JOURNAL ARTICLE DA - 860409 DP - 1986 Mar IS - 0749-0720 TA - Vet Clin North Am Food Anim Pract PG - 147-58 SB - M CY - UNITED STATES IP - 1 VI - 2 JC - CFP AA - Author EM - 8606 AB - The primary purpose of necropsy of the porcine fetus is the collection of tissues to be submitted to the laboratory to assist in identification of the causative agent(s). Proper collection and handling of tissues are critical for optimum identification of infectious agents. Gross examination is an aid in differentiating stillbirth and neonatal death, determining relative time of fetal death, and identifying congenital defects. RO - M:BDS PMID- 3004678 LR - 870624 CU - 93 SO - Vet Clin North Am Food Anim Pract 1986 Mar;2(1):147-58 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 86181483 AU - Broughton ES AU - Scarnell J TI - Vaccination against leptospiral abortion and renal carriage [letter] LA - Eng MH - Abortion, Veterinary/*prevention & control MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - Female MH - Kidney/microbiology MH - Leptospira interrogans/growth & development MH - Pregnancy MH - Vaccination/*veterinary MH - Weil's Disease/prevention & control/*veterinary PT - LETTER DA - 860516 DP - 1986 Feb 15 IS - 0042-4900 TA - Vet Rec PG - 190-1 SB - M CY - ENGLAND IP - 7 VI - 118 JC - XBS EM - 8607 PMID- 3962136 CU - 91 SO - Vet Rec 1986 Feb 15;118(7):190-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 86257035 AU - Pachner AR TI - Spirochetal diseases of the CNS. LA - Eng MH - Central Nervous System Diseases/*complications/diagnosis/etiology/therapy MH - Human MH - Leptospirosis/complications/diagnosis/drug therapy/etiology MH - Lyme Disease/complications/diagnosis/drug therapy/etiology MH - Male MH - Parasitology/trends MH - Prognosis MH - Relapsing Fever/complications/diagnosis/drug therapy/etiology MH - Spirochaetales Infections/*complications/diagnosis/etiology/therapy MH - Syphilis/classification/drug therapy/etiology PT - JOURNAL ARTICLE DA - 860821 DP - 1986 Feb IS - 0733-8619 TA - Neurol Clin PG - 207-22 SB - M CY - UNITED STATES IP - 1 VI - 4 JC - NEU AA - Author EM - 8610 AB - The neurotropism of the spirochete is evident from the above discussions of syphilis, Lyme disease, leptospirosis, and relapsing fever. In all of these diseases, the organism very likely enters the CNS very early in the course of the disease. The fate of the organism then depends on the virulence of the spirochete, the host defenses, and any antibiotic treatment administered. Why Treponema pallidum lays dormant in the CNS and then somehow reactivates is a mystery; the same mystery occurs in Lyme disease. Leptospirosis and relapsing fever seem to be infections much more limited in time, and are not reported to cause these long-term sequelae. The treatment of these last two infections seems to be fairly straightforward. However, the appropriate treatment for the various stages of the disease in both syphilis and Lyme disease in order to prevent long-term sequelae is not universally accepted. At this time, it seems that high-dose intravenous penicillin is the treatment of choice for each of these infections shown to be active in the nervous system. PMID- 3724737 SO - Neurol Clin 1986 Feb;4(1):207-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 86196636 AU - Manca N AU - Verardi R AU - Colombrita D AU - Ravizzola G AU - Savoldi E AU - Turano A TI - Radiometric method for the rapid detection of Leptospira organisms. LA - Eng MH - Human MH - Leptospira interrogans/growth & development/*isolation & purification MH - Radiometry MH - Septicemia/*microbiology MH - Weil's Disease/diagnosis/*microbiology PT - JOURNAL ARTICLE DA - 860530 DP - 1986 Feb IS - 0095-1137 TA - J Clin Microbiol PG - 401-3 SB - M CY - UNITED STATES IP - 2 VI - 23 JC - HSH AA - Author EM - 8608 AB - A rapid and sensitive radiometric method for detection of Leptospira interrogans serovar pomona and Leptospira interrogans serovar copenhageni is described. Stuart's medium and Middlebrook TB (12A) medium supplemented with bovine serum albumin, catalase, and casein hydrolysate and labeled with 14C-fatty acids were used. The radioactivity was measured in a BACTEC 460 (Johnston Laboratories). With this system, Leptospira organisms were detected in human blood in 2 to 5 days, a notably shorter time period than that required for the majority of detection techniques. PMID- 3700624 SO - J Clin Microbiol 1986 Feb;23(2):401-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [168 medline neighbors] UI - 86210728 AU - Isogai E AU - Isogai H AU - Kurebayashi Y AU - Ito N TI - Biological activities of leptospiral lipopolysaccharide. LA - Eng MH - Animal MH - Bone Marrow/pathology MH - Comparative Study MH - Escherichia coli MH - Fever/chemically induced MH - Hemorrhage/chemically induced MH - Immunity, Natural MH - Intestines/pathology MH - Kidney/pathology MH - *Leptospira interrogans/metabolism MH - Lipopolysaccharides/analysis/immunology/isolation & purification/*toxicity MH - Lung/pathology MH - Macrophage Activation MH - Macrophages/physiology MH - Male MH - Mice MH - Necrosis MH - Phagocytosis MH - Rabbits MH - Salmonella Infections, Animal/immunology MH - Spleen/pathology RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 860610 DP - 1986 Feb IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 53-64 SB - M CY - GERMANY, WEST IP - 1 VI - 261 JC - Y55 AA - Author EM - 8608 AB - Lipopolysaccharide extracted with phenol-water from Leptospira interrogans serovar copenhageni strain Shibaura (L-LPS) showed various biological activities. In lethality for mice, L-LPS was active (LD 50, 3.4 mg/mouse) but about 12 times less potent than Escherichia coli LPS (E-LPS) per weight basis. L-LPS had pyrogenicity for rabbits, and the fever curves showed no evidence of the classical biphasic fever produced by E-LPS. In the bone marrow of mice, L-LPS caused hemorrhages and necrosis but less severe than those caused by E-LPS. Histopathologically, fresh hemorrhages were found in the intestine, spleen, lung and the other organs at 24 h after inoculation of L-LPS. Necrosis was also found in these organs and was particularly severe in mice inoculated with more than 2 mgL-LPS. Liver necrosis was found at 7th day after inoculation of L-LPS but not after inoculation of E-LPS. L-LPS had adjuvant activity just like E-LPS. L-LPS enhanced non- specific resistance to Salmonella infection and activated mouse peritoneal macrophages to kill these organisms. L-LPS was positive in limulus test just like E-LPS. These results demonstrated similarities of L-LPS and E-LPS. Some toxic effects of L-LPS were less than those of E-LPS, but some effects of L-LPS were more than those of E-LPS. L-LPS was antigenically active and the specificity was serogroup-associated. L-LPS was composed of carbohydrate (54%), lipid (12%), protein (5%). Arabinose, xylose and rhamnose were major sugars as detected by gas chromatography. 2-keto-deoxyoctanate (KDO) was not detectable. PMID- 3518294 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1986 Feb;261(1):53-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 86186503 AU - Cousins DV AU - Robertson GM TI - Use of enzyme immunoassay in a serological survey of leptospirosis in sheep. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Australia MH - IgG/analysis MH - IgM/analysis MH - Immunoenzyme Techniques MH - Leptospira interrogans/classification/*immunology MH - Male MH - Sheep MH - Sheep Diseases/*epidemiology/immunology MH - Weil's Disease/epidemiology/immunology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860429 DP - 1986 Feb IS - 0005-0423 TA - Aust Vet J PG - 36-9 SB - M CY - AUSTRALIA IP - 2 VI - 63 JC - 9IE AA - Author EM - 8607 AB - A total of 731 serums, all from Merino rams from 20 farms, were tested for antibodies against Leptospira interrogans serovars hardjo, pomona and tarassovi using the microscopic agglutination test (MAT). The enzyme immunoassay (EIA) technique was used to test all serums for IgM and IgG antibodies to serovar hardjo. In the MAT, reactions to serovar hardjo were most common with 236 rams (32.3%) reacting at 1/100 or greater. Only 1.9% of serums reacted against serovar tarassovi and 1.1% against serovar pomona. The percentage of sheep with positive MAT reactions to serovar hardjo ranged from 0 0 to 94.9 between farms. When using EIA, 46 (6.2%) of the serums were positive for IgM antibody and 246 (33.6%) were positive for IgG antibody. Correlation of the EIA for detection of IgG antibody with the MAT was good. The EIA detection of IgG antibody was considered to be a good alternative test to the MAT for epidemiological studies in sheep. PMID- 3516131 CU - 91 SO - Aust Vet J 1986 Feb;63(2):36-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 86143738 AU - Ballard SA AU - Williamson M AU - Adler B AU - Vinh T AU - Faine S TI - Interactions of virulent and avirulent leptospires with primary cultures of renal epithelial cells. LA - Eng MH - Adhesiveness MH - Animal MH - Antibodies, Bacterial MH - Antigen-Antibody Reactions MH - Cells, Cultured MH - Epithelium/microbiology MH - Fluorescent Antibody Technique MH - Kidney Tubules/*microbiology MH - Leptospira/*growth & development/immunology/pathogenicity MH - Mice MH - Microscopy, Electron, Scanning MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860401 DP - 1986 Feb IS - 0022-2615 TA - J Med Microbiol PG - 59-67 SB - M CY - ENGLAND IP - 1 VI - 21 JC - J2N AA - Author EM - 8606 AB - A primary culture system for the cells of mouse renal-tubular epithelium was established and used to observe the adhesion of leptospires. Virulent strains of serovars copenhageni and ballum attached themselves to epithelial cells within 3 h of infection whereas an avirulent variant of serovar copenhageni did not adhere to epithelial cells at all within the experimental period of 24 h. The saprophytic Leptospira biflexa serovar patoc became attached non- specifically to inert glass surfaces as well as to the cells. The adhesion of leptospires to epithelial cells was not inhibited by homologous antibody. PMID- 3512834 CU - 91 SO - J Med Microbiol 1986 Feb;21(1):59-67 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 86210729 AU - Isogai E AU - Kitagawa H AU - Isogai H AU - Kurebayashi Y AU - Ito N TI - Phagocytosis as a defense mechanism against infection with leptospiras. LA - Eng MH - Animal MH - Antibodies, Monoclonal/immunology MH - Immunity, Active MH - Immunization MH - Immunization, Passive MH - Leptospira interrogans/immunology/ultrastructure MH - Lipopolysaccharides/immunology MH - Macrophages/*immunology/ultrastructure MH - Male MH - Mice MH - Mice, Inbred BALB C MH - Microscopy, Electron MH - *Phagocytosis MH - Silicon Dioxide/pharmacology MH - Support, Non-U.S. Gov't MH - Weil's Disease/*immunology/metabolism RN - 0 (Antibodies, Monoclonal) RN - 0 (Lipopolysaccharides) RN - 7631-86-9 (Silicon Dioxide) PT - JOURNAL ARTICLE DA - 860610 DP - 1986 Feb IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 65-74 SB - M CY - GERMANY, WEST IP - 1 VI - 261 JC - Y55 AA - Author EM - 8608 AB - The role of macrophages in host defense was studied in vivo and in vitro. The intravenous administration of silica, an agent reported to selectively inactivate macrophages, increased the sensitivity to leptospiral infection and inhibited bacterial clearance. Active immunization with killed organisms or with leptospiral lipopolysaccharide (L-LPS), and passive immunization with a monoclonal antibody showed powerful protective effects against infection in mice. The effect of immunization decreased in silica-treated mice. These findings were supported by electron microscopic examination and observation of killing by macrophages in vitro. PMID- 3010604 CU - 93 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1986 Feb;261(1):65-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 86153494 AU - Ellis WA AU - McParland PJ AU - Bryson DG AU - Cassells JA TI - Prevalence of Leptospira infection in aborted pigs in Northern Ireland. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Female MH - Kidney/microbiology MH - Leptospira/pathogenicity MH - Leptospirosis/microbiology/*veterinary MH - Lung/microbiology MH - Placenta/microbiology MH - Pregnancy MH - Serotyping MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 860409 DP - 1986 Jan 18 IS - 0042-4900 TA - Vet Rec PG - 63-5 SB - M CY - ENGLAND IP - 3 VI - 118 JC - XBS AA - Author EM - 8606 AB - During an investigation of pig abortions and stillbirths in Northern Ireland, leptospires were isolated from 55 of the 78 litters examined. Strains belonging to four serogroups (Australis, Icterohaemorrhagiae, Hebdomadis and Autumnalis) were recovered but leptospires of the Australis serogroup accounted for 91 per cent of the isolates. Two serovars of the Australis group bratislava and muenchen, were identified. PMID- 3952941 SO - Vet Rec 1986 Jan 18;118(3):63-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 86124599 AU - Ellis WA AU - Songer JG AU - Montgomery J AU - Cassells JA TI - Prevalence of Leptospira interrogans serovar hardjo in the genital and urinary tracts of non-pregnant cattle. LA - Eng MH - Abattoirs MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacteriological Techniques MH - Blood/microbiology MH - Carrier State/microbiology/veterinary MH - Cattle/*microbiology MH - Cattle Diseases/microbiology MH - Comparative Study MH - Culture Media MH - Female MH - Genital Diseases, Female/microbiology/veterinary MH - Genitalia, Female/*microbiology MH - Kidney Diseases/microbiology/veterinary MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/microbiology/veterinary MH - Urinary Tract/*microbiology RN - 0 (Antibodies, Bacterial) RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 860318 DP - 1986 Jan 4 IS - 0042-4900 TA - Vet Rec PG - 11-3 SB - M CY - ENGLAND IP - 1 VI - 118 JC - XBS AA - Author EM - 8605 AB - In a bacteriological investigation of 60 cows and heifers from an abattoir Leptospira interrogans serovar hardjo was isolated from 39 (65 per cent) animals. The genital tract (57 per cent) appeared to be as important a site of hardjo localisation as the urinary tract (62 per cent). This is believed to be the first report of genital hardjo infection in naturally infected cattle. PMID- 3511601 CU - 91 SO - Vet Rec 1986 Jan 4;118(1):11-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 86168322 AU - Nervig RM AU - Sebring RW AU - Scheevel KF TI - The enumeration of Leptospira interrogans serovar pomona by a bioluminescence ATP assay. LA - Eng MH - Adenosine Triphosphate/*analysis MH - Animal MH - Leptospira interrogans/*analysis MH - Luciferase/metabolism MH - Luciferin/metabolism MH - *Luminescence MH - Nephelometry and Turbidimetry RN - EC 1.13.12.- (Luciferase) RN - 0 (Luciferin) RN - 56-65-5 (Adenosine Triphosphate) PT - JOURNAL ARTICLE DA - 860509 DP - 1986 Jan IS - 0092-1157 TA - J Biol Stand PG - 21-4 SB - M CY - ENGLAND IP - 1 VI - 14 JC - HJD AA - Author EM - 8607 AB - A rapid method for enumerating viable Leptospira interrogans serovar pomona cells was investigated using a bacterial adenosine triphosphate (ATP) assay. The ATP was assayed by the luciferin-luciferase bioluminescence reaction. Samples of serovar pomona grown in liquid polysorbate 80-bovine albumin (P80-BA) medium for 1-3 days were analysed for ATP content, culture density (nephelometry), direct cell count and most probable number of viable cells (MPNVC) as determined by the dilution tube technique. A linear relationship was found between ATP content and the number of viable cells over the range of 4 X 10(8) to 8 X 10(9) leptospires/ml. Over this range the correlation coefficient for ATP content versus viable cells (0.96) was similar to the coefficient for culture density versus the number of viable cells. The coefficient for direct counts versus the number of viable cells was smaller. The bioluminescence assay of bacterial ATP is a promising method for enumerating viable leptospires in pure culture. PMID- 3957938 CU - 91 SO - J Biol Stand 1986 Jan;14(1):21-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 87154587 AU - Perdrix C AU - Clement C AU - Druart F TI - [Acute respiratory distress disclosing leptospirosis] LA - Fre MH - Acute Disease MH - Case Report MH - English Abstract MH - Female MH - Follow-Up Studies MH - Hemodynamics MH - Human MH - Leptospirosis/*complications MH - Middle Age MH - Respiratory Distress Syndrome, Adult/*etiology/physiopathology PT - JOURNAL ARTICLE DA - 870409 DP - 1986 IS - 0750-7658 TA - Ann Fr Anesth Reanim PG - 599-600 SB - M CY - FRANCE IP - 6 VI - 5 JC - 4ZT AA - Author EM - 8706 AB - The respiratory manifestations of leptospirosis are usually benign. A case is reported of anicteric leptospirosis with serious pulmonary affection. The clinical symptoms, the radiological manifestations and haemodynamic investigation were suggestive of an acute respiratory distress by non-haemodynamic pulmonary oedema. In accordance with other authors, one would be justified in including this acute respiratory failure as part of the acute respiratory distress syndrome of the adult (ARDS). PMID- 3826792 TT - Detresse respiratoire aigue revelant une leptospirose. EA - A SO - Ann Fr Anesth Reanim 1986;5(6):599-600 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 87119048 AU - Anusz Z TI - [Brucellosis and other zoonoses--1984] LA - Pol MH - Adult MH - Aged MH - Animal MH - Brucellosis/*epidemiology MH - Brucellosis, Bovine/epidemiology MH - Cattle MH - Erysipeloid/epidemiology MH - Female MH - Human MH - Leptospirosis/epidemiology MH - Male MH - Middle Age MH - Poland MH - Toxoplasmosis/epidemiology PT - JOURNAL ARTICLE DA - 870303 DP - 1986 IS - 0033-2100 TA - Przegl Epidemiol PG - 205-11 CY - POLAND IP - 2 VI - 40 JC - Q8T EM - 8705 PMID- 3809537 CU - 88 TT - Bruceloza i inne choroby odzwierzece--1984 rok. SO - Przegl Epidemiol 1986;40(2):205-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 87104077 AU - Bettelheim KA AU - Fogg TR TI - Serological studies on leptospiral antibodies in dairy milkers in three regions of the South Island of New Zealand. LA - Eng MH - Adult MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle/immunology MH - *Dairying MH - Female MH - Human MH - Leptospira interrogans/*immunology MH - Male MH - Middle Age MH - New Zealand RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 870306 DP - 1986 IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 355-64 SB - M CY - ENGLAND IP - 4 VI - 9 JC - DNN AA - Author EM - 8705 AB - The antibody levels of leptospiral antigens among dairy herds were determined and correlated with those of the milkers in three areas of the South Island of New Zealand. The milkers filled out an extensive questionnaire giving age and sex of the milker, as well as details of the herd milked and his/her association with it. The serological results are compared with these data and the value of such seroepidemiological studies examined from the point of view of the advantages of vaccinating cattle to protecting the milker from leptospirosis. Antibodies to L. interrogans serovar hardjo were the ones most frequently encountered among the milkers; however, antibodies to other serovars were also noted. Some animals in most herds had antibodies to serovar hardjo. These studies suggest that vaccinating cattle with serovar hardjo would not necessarily reduce the human incidence of leptospirosis in this population. PMID- 3802763 CU - 91 SO - Comp Immunol Microbiol Infect Dis 1986;9(4):355-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 87043031 AU - Primachenko NB AU - Komnova ZD AU - Beliak GM TI - [Characteristics of disseminated intravascular coagulation in leptospirosis] LA - Rus MH - Adult MH - Disseminated Intravascular Coagulation/*diagnosis/etiology/pathology MH - English Abstract MH - Human MH - Kidney/pathology MH - Liver/pathology MH - Lung/pathology MH - Male MH - Middle Age MH - Myocardium/pathology MH - Weil's Disease/*complications/pathology PT - JOURNAL ARTICLE DA - 861216 DP - 1986 IS - 0038-5077 TA - Sov Med PG - 23-6 CY - USSR IP - 8 JC - UW7 EM - 8702 PMID- 3775509 TT - Kharakteristika disseminirovannogo vnutrisosudistogo svertyvaniia krovi pri leptospiroze. EA - A SO - Sov Med 1986;(8):23-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 86252183 AU - Volina EG AU - Levina LF AU - Soboleva GL TI - Phospholipase activity and virulence of pathogenic leptospirae. LA - Eng MH - Agar MH - Comparative Study MH - Culture Media MH - Leptospira/*enzymology/pathogenicity MH - Phosphatidylcholines MH - Phospholipases/*metabolism MH - Phospholipases A/*metabolism RN - EC 3.1.- (Phospholipases) RN - EC 3.1.1.- (Phospholipases A) RN - 0 (Culture Media) RN - 0 (Phosphatidylcholines) RN - 9002-18-0 (Agar) PT - JOURNAL ARTICLE DA - 860814 DP - 1986 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 163-9 SB - M CY - CZECHOSLOVAKIA IP - 2 VI - 30 JC - IEV AA - Author EM - 8610 AB - Results of investigation of phospholipase activity and virulence of pathogenic leptospirae on a solid nutrient medium using the method of agar layers with 1% of L-lecithin in the medium of the second layer are presented. It has been demonstrated that only one zone of translucent medium is formed around the colonies of pathological leptospirae, which is obviously due to the release of phospholipase A. The examined virulent strains of pathogenic leptospirae were found to exhibit greater phospholipase activity (width of the translucent zones being 5.0 +/- 0.34 mm) than the avirulent strains (width of the zones being 1.5 +/- 0.11 mm). PMID- 3722810 CU - 92 SO - J Hyg Epidemiol Microbiol Immunol 1986;30(2):163-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 86226136 AU - Vinh T AU - Adler B AU - Faine S TI - Glycolipoprotein cytotoxin from Leptospira interrogans serovar copenhageni. LA - Eng MH - Animal MH - Chromatography, High Pressure Liquid MH - Complement Fixation Tests MH - Cytotoxicity Tests, Immunologic MH - Cytotoxins/*analysis/immunology MH - Fatty Acids/analysis MH - Leptospira interrogans/*analysis MH - Lipopolysaccharides/analysis MH - Lipoproteins/analysis MH - Mice MH - Microscopy, Electron MH - Neutralization Tests MH - Support, Non-U.S. Gov't RN - 0 (Cytotoxins) RN - 0 (Fatty Acids) RN - 0 (Lipopolysaccharides) RN - 0 (Lipoproteins) PT - JOURNAL ARTICLE DA - 860724 DP - 1986 Jan IS - 0022-1287 TA - J Gen Microbiol PG - 111-23 SB - M CY - ENGLAND VI - 132 ( Pt 1) JC - I87 AA - Author EM - 8609 AB - Lipopolysaccharide (LPS), glycolipoprotein (GLP) and lipid extract were prepared from Leptospira interrogans serovar copenhageni. GLP, lipid extract or purified fatty acids from lipid extract produced cytotoxic effects seen as cell enzyme leakage followed by cytotoxic death when tested in mouse fibroblast L929 cells in tissue culture. All extracts also agglutinated mouse erythrocytes but purified LPS was not cytotoxic. Neither GLP nor LPS were pyrogenic but both gelled Limulus amoebocyte lysate. Specific anti-GLP IgG neutralized the cytotoxic and haemagglutinating effect of GLP; however, at higher concentrations it enhanced the cytotoxicity of GLP and mediated lysis of the erythrocytes. A high dose of leptospires (i.e. 10(10) organisms) killed weanling mice causing pathological changes similar to those seen in acute leptospirosis. Similar results were obtained with live, dead, pathogenic and saprophytic leptospires. The results suggest that toxicity is involved in leptospiral infection and that lipid components either of whole leptospires or of a leptospiral GLP may contribute to the pathogenesis of acute leptospirosis. PMID- 3711858 CU - 92 SO - J Gen Microbiol 1986 Jan;132 ( Pt 1):111-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 86226135 AU - Vinh T AU - Adler B AU - Faine S TI - Ultrastructure and chemical composition of lipopolysaccharide extracted from Leptospira interrogans serovar copenhageni. LA - Eng MH - Chemistry MH - Chromatography, Gas MH - Fatty Acids/analysis MH - Leptospira interrogans/*analysis MH - Lipopolysaccharides/*analysis MH - Microscopy, Electron MH - Monosaccharides/analysis MH - Support, Non-U.S. Gov't RN - 0 (Fatty Acids) RN - 0 (Lipopolysaccharides) RN - 0 (Monosaccharides) PT - JOURNAL ARTICLE DA - 860724 DP - 1986 Jan IS - 0022-1287 TA - J Gen Microbiol PG - 103-9 SB - M CY - ENGLAND VI - 132 ( Pt 1) JC - I87 AA - Author EM - 8609 AB - Lipopolysaccharide (LPS) from Leptospira interrogans serovar copenhageni was prepared from the aqueous phase of a phenol/water extract. Electron microscopic examination of negatively stained LPS showed a mixture of ribbon-like, round and ring structures. Carbohydrate analysis of the preparations revealed pentoses, hexoses, heptoses, hexosamines, and a 2-keto-3-deoxyonic acid which was chromatographically different from authentic 2-keto-3-deoxyoctonic acid (KDO). The major fatty acids of the LPS were hydroxylauric, palmitic and oleic acids. Although the leptospiral LPS preparations did not contain KDO or hydroxymyristic acid, they were otherwise morphologically and chemically similar to the LPS of other Gram- negative bacteria. PMID- 3711857 CU - 92 SO - J Gen Microbiol 1986 Jan;132 ( Pt 1):103-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [90 medline neighbors] UI - 88069303 AU - Stanchi NO AU - Grisolia CS AU - Martino PE AU - Peluso FO TI - [Presence of antileptospira antibodies in ophidia in Argentina] LA - Spa MH - Animal MH - Antibodies, Bacterial/*analysis MH - Argentina MH - English Abstract MH - Leptospira/*immunology MH - Snakes/*immunology MH - Support, Non-U.S. Gov't MH - Zoonoses RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 871229 DP - 1986 IS - 0325-7541 TA - Rev Argent Microbiol PG - 127-30 SB - M CY - ARGENTINA IP - 3-4 VI - 18 JC - QZ8 AA - Author EM - 8803 AB - Sera obtained from 18 Bothrops alternatus and 2 Phylodrias burmeisteri were analyzed for the presence of antileptospiral antibodies using a microscopic agglutination test. Out of 18 Bothrops sera, 13 (72%) gave positive results. Snake serum reacted with patoc, andamana, wolffi, tarassovi, pomona, pyrogenes and shermani serovars. It can be concluded that Leptospiral antibodies are present in snake sera in Argentina, suggesting that the circulating antibodies may have an important role in the epizoothiology of the disease. AD - Catedra de Microbiologia, Facultad de Ciencias Veterinarias, Universidad Nacional de la Plata, Argentina. PMID- 3685389 CU - 91 TT - Presencia de anticuerpos antileptospiras en ofidios de Argentina. EA - A SO - Rev Argent Microbiol 1986;18(3-4):127-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 88069297 AU - Russo de Bordoy AM TI - [Serologic prevalence of human leptospirosis in 2 different groups in the province of Formosa, Argentina] LA - Spa MH - Adult MH - Antibodies, Bacterial/*analysis MH - Argentina MH - Comparative Study MH - English Abstract MH - Female MH - Human MH - Leptospira/*classification/immunology MH - Leptospirosis/immunology/*microbiology MH - Male RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 871229 DP - 1986 IS - 0325-7541 TA - Rev Argent Microbiol PG - 75-8 SB - M CY - ARGENTINA IP - 2 VI - 18 JC - QZ8 AA - Author EM - 8803 AB - Sera from two different human group from the Province of Formosa were checked for 14 leptospira serovars, using Martin & Petti's microagglutination test with live antigens. In the first group, consisting of 605 males from the whole province, sampled during premilitary medical screening, 20 were found positive (3.3%). The predominant serovars were as follows: L. bratislava (50%), L. pomona (25%), L. butembo and L. icterohemorragica (20%), L. canicola (15%) and last L. wolffii (5%). In the second group, the sera were obtained from the local Central Hospital, and were taken from adults of both sexes, from a limited area of the province. With regard to Group I, there was a high number of positive (32.3%) and a variation in the frequency of serovars, the results being as follows: L. butembo (38.8%), L. pomona (33.3%), L. bratislava (31.4%), L. icterohemorragica (12.9%), L. borincana (3.7%) and finally L. canicola, L. pyrogenes, L. wolffii and L. bataviae (1.8%). AD - Centro de Diagnostico e Investigaciones Veterinarias, Formosa, Argentina. PMID- 3685384 CU - 91 TT - Prevalencia serologica de leptospirosis humana en dos grupos diferentes en la provincia de Formosa, Argentina. EA - A SO - Rev Argent Microbiol 1986;18(2):75-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [22 medline neighbors] UI - 87264671 AU - Wessels G AU - Hesseling PB AU - Cooper RC TI - Q-fever, OX19, OX2 and leptospirosis antibodies in patients with onyalai and in negroid, bushman and white inhabitants of Kavango, Namibia [letter] LA - Eng MH - Antibodies, Bacterial/*analysis MH - *Blacks MH - Human MH - Male MH - Namibia MH - Purpura, Thrombocytopenic/*immunology RN - 0 (Antibodies, Bacterial) PT - LETTER DA - 870731 DP - 1986 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 847-8 SB - M CY - ENGLAND IP - 5 VI - 80 JC - WBU EM - 8710 PMID- 3603625 CU - 91 SO - Trans R Soc Trop Med Hyg 1986;80(5):847-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 87181857 AU - Norris SH TI - Diarrheal illness complicated by acute renal failure. LA - Eng MH - Case Report MH - Diagnosis, Differential MH - Diarrhea/*complications MH - Hemolytic-Uremic Syndrome/*diagnosis/etiology MH - Human MH - Kidney Failure, Acute/*complications MH - Leptospirosis/diagnosis MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 870511 DP - 1986 IS - 0250-8095 TA - Am J Nephrol PG - 470, 489 SB - M CY - SWITZERLAND IP - 6 VI - 6 JC - 3MB EM - 8707 PMID- 3565504 SO - Am J Nephrol 1986;6(6):470, 489 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 90018655 AU - Leal NC AU - Cavalcanti TI AU - de Melo ME AU - Brasil DP AU - Andrade J TI - [Detection of leptospirosis in rats in the city of Recife, Pernambuco, 1983-1985] LA - Por MH - Animal MH - Antibodies, Bacterial/analysis MH - Brazil MH - English Abstract MH - Hemagglutination Tests MH - Leptospira/immunology MH - Leptospirosis/*veterinary MH - Muridae MH - Rats MH - Rodent Diseases/*diagnosis MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 891028 DP - 1986 IS - 0034-7256 TA - Rev Bras Malariol Doencas Trop PG - 45-9 CY - BRAZIL VI - 38 JC - RI9 EM - 9001 PMID- 3267858 CU - 91 NP - X TT - Deteccao de leptospirose em ratos da cidade do Recife, Pernambuco, no periodo de 1983-1985. EA - A SO - Rev Bras Malariol Doencas Trop 1986;38:45-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 90198316 AU - Bey RF AU - Johnson RC TI - Current status of leptospiral vaccines. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - *Bacterial Vaccines MH - Leptospira/*immunology MH - Leptospirosis/prevention & control/*veterinary MH - Vaccination/*veterinary MH - Vaccines, Attenuated MH - Vaccines, Inactivated RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (Vaccines, Attenuated) RN - 0 (Vaccines, Inactivated) PT - JOURNAL ARTICLE PT - REVIEW PT - REVIEW, ACADEMIC DA - 900427 DP - 1986 IS - 0255-3686 TA - Prog Vet Microbiol Immunol PG - 175-97 SB - M CY - SWITZERLAND VI - 2 JC - AOC EM - 9007 AD - Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St. Paul. RF - 128 PMID- 3078649 CU - 92 NP - X SO - Prog Vet Microbiol Immunol 1986;2:175-97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 86144173 AU - Ingebrigtsen DK AU - Ludwig JR AU - McClurkin AW TI - Occurrence of antibodies to the etiologic agents of infectious bovine rhinotracheitis, parainfluenza 3, leptospirosis, and brucellosis in white-tailed deer in Minnesota. LA - Eng MH - Animal MH - Animals, Wild/immunology/microbiology MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - Brucellosis/immunology MH - Deer/*immunology/microbiology MH - Herpesvirus 1, Bovine/immunology MH - Leptospira/immunology MH - Leptospirosis/immunology MH - Parainfluenza Virus 3, Human/immunology MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 860408 DP - 1986 Jan IS - 0090-3558 TA - J Wildl Dis PG - 83-6 SB - M CY - UNITED STATES IP - 1 VI - 22 JC - KEM AA - Author EM - 8606 AB - A serologic survey was conducted on 628 white-tailed deer (Odocoileus virginianus) in 1976 and 1979-1980. Tests for antibodies to the etiologic agents of infectious bovine rhinotrancheitis (IBR), parainfluenza 3 (PI3), leptospirosis, and brucellosis produced positive results of 15%, 20%, 3% and 0%, respectively. Adult deer had significantly higher prevalence of antibodies to IBR virus and PI3 virus than fawns. These data provide a basis for monitoring these disease agents in Minnesota's white-tailed deer. PMID- 3005666 CU - 96 SO - J Wildl Dis 1986 Jan;22(1):83-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 86128510 AU - Thiermann AB AU - Handsaker AL AU - Foley JW AU - White FH AU - Kingscote BF TI - Reclassification of North American leptospiral isolates belonging to serogroups Mini and Sejroe by restriction endonuclease analysis. LA - Eng MH - Comparative Study MH - DNA Restriction Enzymes MH - DNA, Bacterial/*analysis MH - *Genes, Bacterial MH - Leptospira/*classification/genetics MH - *Serotyping RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 860320 DP - 1986 Jan IS - 0002-9645 TA - Am J Vet Res PG - 61-6 SB - M CY - UNITED STATES IP - 1 VI - 47 JC - 40C AA - Author EM - 8605 AB - The genomes of North American strains of leptospires belonging to serogroups Mini and Sejroe were analyzed and compared with those of reference strains by cleavage with restriction endonucleases. The isolates selected for this study, when typed by the serologic method, were identified as serovars szwajizak, hardjo, and balcanica. However, the results of restriction endonuclease analysis (REA) indicated that a different classification existed. The 2 isolates typed as serovar szwajizak seem to be georgia by REA. Isolates belonging to serovars balcanica and hardjo had REA patterns that differed from both reference strains. Differences were not observed in the REA patterns between balcanica and hardjo isolates. All hardjo and balcanica isolates examined are suggested to be classified into a previously described hardjo, REA subtype hardjobovis. Using the enzyme Hha1, these isolates were subdivided into 3 subgroups. When examining the REA pattern of the 17 reference strains in serogroup Sejroe, 3 identical pairs were observed: wolffi and roumanica; sejroe and polonica; and istrica and nyanza. The REA again indicated that it will be a valuable method for the classification of leptospires. PMID- 3004267 CU - 93 SO - Am J Vet Res 1986 Jan;47(1):61-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 86085701 AU - Yelton DB AU - Cohen RA TI - Analysis of cloned DNA from Leptospira biflexa serovar patoc which complements a deletion of the Escherichia coli trpE gene. LA - Eng MH - *Chromosome Deletion MH - *Cloning, Molecular MH - DNA Insertion Elements MH - DNA, Bacterial/*analysis MH - Escherichia coli/*genetics MH - *Genes, Bacterial MH - *Genetic Complementation Test MH - Leptospira/*genetics MH - Mutation MH - Operon MH - Support, Non-U.S. Gov't MH - Tryptophan/*biosynthesis RN - 0 (DNA Insertion Elements) RN - 0 (DNA, Bacterial) RN - 6912-86-3 (Tryptophan) PT - JOURNAL ARTICLE DA - 860220 DP - 1986 Jan IS - 0021-9193 TA - J Bacteriol PG - 41-6 SB - M CY - UNITED STATES IP - 1 VI - 165 JC - HH3 AA - Author EM - 8604 AB - To analyze the cloned region of the chromosome of the spirochete Leptospira biflexa serovar patoc which complemented a defect in the trpE gene of Escherichia coli, we performed a series of experiments involving subcloning, transposon mutagenesis, and maxicells. By subcloning into pBR322 we were able to isolate the Leptospira genes on a 9.7-kilobase pair plasmid (pYC6). Transposon mutagenesis with Tn5 identified a 2.8-kilobase pair region of this plasmid as being necessary to complement a trpE deletion mutation in E. coli. Transformation of plasmid pYC6 into E. coli cells deleted for trpE and the proximal end of trpD showed that the Leptospira DNA complemented both defects. A maxicell analysis of various transposon-induced mutations of the plasmid revealed that three proteins (53.5, 23.6, and 22 kilodaltons) were encoded by the 2.8-kilobase pair region of the Leptospira genome. Two different promoters controlled the production of these three proteins. PMID- 3001031 CU - 93 SO - J Bacteriol 1986 Jan;165(1):41-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 86234404 AU - Popa DP AU - Tacorian D AU - Andreescu N AU - Ciurea L TI - [Ocular manifestations of leptospirosis: methods of diagnosis, surveillance and treatment] LA - Rum MH - Adult MH - Aged MH - English Abstract MH - Female MH - Human MH - Leptospira/classification MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Occupational Diseases/*complications MH - Serotyping MH - Uveitis/diagnosis/*etiology PT - JOURNAL ARTICLE DA - 860714 DP - 1986 Jan-Mar IS - 0377-7863 TA - Rev Chir Oncol Radiol O R L Oftalmol Stomatol Ser Oftalmol PG - 11-6 CY - ROMANIA IP - 1 VI - 30 JC - RMF EM - 8609 PMID- 2940629 CU - 92 TT - Manifestari oculare in leptospiroze; metode de diagnostic, urmarire si tratament. EA - A SO - Rev Chir Oncol Radiol O R L Oftalmol Stomatol Ser Oftalmol 1986 Jan- Mar;30(1):11-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 86309160 AU - Borozdov NI AU - Chernukha IuG AU - Amfiteatrova NF TI - [A method of determining cell viability in Leptospira cultures] LA - Rus MH - Acrylamides/pharmacology MH - Cell Division/drug effects MH - Culture Media MH - English Abstract MH - Leptospira/*cytology/growth & development MH - Methods RN - 0 (Acrylamides) RN - 0 (Culture Media) RN - 79-06-1 (acrylamide) PT - JOURNAL ARTICLE DA - 860929 DP - 1986 IS - 0023-6748 TA - Lab Delo PG - 369-70 CY - USSR IP - 6 JC - KYU EM - 8612 PMID- 2427789 CU - 95 TT - Metod opredeleniia zhiznesposobnykh kletok v kul'turakh mikroorganizmov roda Leptospira. EA - A SO - Lab Delo 1986;(6):369-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 86228958 AU - Volina EG AU - Sarukhanova LE AU - Levina LF TI - [Use of different methods of determining the hemolytic activity of Leptospira on solid nutrient media] LA - Rus MH - Animal MH - Bacteriological Techniques MH - Cattle MH - Comparative Study MH - Culture Media/*pharmacology MH - English Abstract MH - *Hemolysis MH - Leptospira/*pathogenicity MH - Rabbits RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 860709 DP - 1986 IS - 0023-6748 TA - Lab Delo PG - 201-4 CY - USSR IP - 4 JC - KYU EM - 8609 PMID- 2423748 CU - 95 TT - Ispol'zovanie razlichnykh metodov opredeleniia gemoliticheskoi aktivnosti leptospir na plotnykh pitatel'nykh sredakh. EA - A SO - Lab Delo 1986;(4):201-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 86192769 AU - Yasuda PH AU - Hoshino-Shimizu S AU - Yamashiro EH AU - De Brito T TI - Experimental leptospirosis (L. interrogans serovar icterohaemorrhagiae) of the guinea pig: leptospiral antigen, gamma globulin and complement C3 detection in the kidney. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Complement Fixation Tests MH - Complement 3/*analysis MH - Fluorescent Antibody Technique MH - Gamma-Globulins/*analysis MH - Guinea Pigs MH - Kidney/analysis/*immunology MH - Leptospirosis/*immunology/pathology MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (Complement 3) RN - 0 (Gamma-Globulins) PT - JOURNAL ARTICLE DA - 860523 DP - 1986 IS - 0232-1513 TA - Exp Pathol PG - 35-43 SB - M CY - GERMANY, EAST IP - 1 VI - 29 JC - EQR AA - Author EM - 8608 AB - Morphofunctional and immunofluorescent studies were done in guinea pigs experimentally infected with Leptospira interrogans serovar icterohaemorrhagiae to determine the role of leptospiral antigen, gamma- globulin, and complement C3 deposits in the pathogenesis of the renal lesions. A sharp increase in leptospiral antigen deposits was observed in the late phase of the experimental infection. Immunoglobulin and complement C3 were small compared with the heavy leptospiral antigen deposits. Moreover, leptospiral antigen was observed mainly in the interstitium whereas immunoglobulin and complement C3 deposits were seen in glomeruli and small blood vessel walls. In our experimental model bacterial migration and local liberation of factors causing virulence seems more likely to determine the renal damage. PMID- 2422052 CU - 95 SO - Exp Pathol 1986;29(1):35-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 86153482 AU - Marshall RB AU - Winter PJ AU - Thiermann AB AU - Ellis WA TI - Genotypes of Leptospira interrogans serovar hardjo in cattle in the UK. LA - Eng MH - Animal MH - Cattle MH - DNA, Bacterial/genetics MH - Electrophoresis, Polyacrylamide Gel MH - *Genotype MH - Leptospira interrogans/*genetics RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 860328 DP - 1985 Dec 21-28 IS - 0042-4900 TA - Vet Rec PG - 669-70 SB - M CY - ENGLAND IP - 25-26 VI - 117 JC - XBS EM - 8606 PMID- 4095887 CU - 91 SO - Vet Rec 1985 Dec 21-28;117(25-26):669-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 86154514 AU - Fukushima H AU - Nakamura R AU - Iitsuka S AU - Ito Y AU - Saito K TI - Presence of zoonotic pathogens (Yersinia spp., Campylobacter jejuni, Salmonella spp., and Leptospira spp.) simultaneously in dogs and cats. LA - Eng MH - Animal MH - Campylobacter fetus/isolation & purification MH - Campylobacter Infections/*transmission MH - Cats/*microbiology MH - Dogs/*microbiology MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*transmission MH - Salmonella/isolation & purification MH - Salmonella Infections/*transmission MH - Seasons MH - Serotyping MH - Temperature MH - Yersinia/isolation & purification MH - Yersinia Infections/*transmission MH - Zoonoses/*transmission PT - JOURNAL ARTICLE DA - 860328 DP - 1985 Dec IS - 0174-3015 TA - Zentralbl Bakteriol Mikrobiol Hyg [B] PG - 430-40 SB - M CY - GERMANY, WEST IP - 3-5 VI - 181 JC - Y5R AA - Author EM - 8606 AB - The purpose of this study was to determine the presence of zoonotic pathogens simultaneously in animals. The isolation of human pathogenic Yersinia enterocolitica (Ye), Yersinia pseudotuberculosis (Yp), Campylobacter jejuni (Cj), Salmonella spp. (Sal) and Leptospira spp. (Lep) in 318 cats and 252 dogs were performed in Shimane Prefecture, Japan. A total of 13 isolates of Yp (4 strains) and Sal (9 strains) were recovered from intestine and/or mesenteric lymph nodes (MLN) of 13 cats (4.1%) but not Ye, and Cj was not examined. A total of 88 isolates of Ye (15 dogs, 15 strains), Yp (16 dogs, 16 strains), Cj (10 dogs, 13 strains) and Sal (39 dogs, 44 strains) were recovered from intestine and/or MLN of 76 dogs (30.2%). Two species of Ye O3, Cj and Sal were recovered from either intestine or MLN of 4 dogs but not from cats. Lep was not detected in dogs and cats kidney. The 101 isolates from dogs and cats belonged to Ye 3B/O3/II (biotype/serotype/phage type) (2 strains), 4/O3/VIII (10 strains) and 2/O5,27 (3 strains), Yp serotypes 1b, 2b (each 3 strains), 2c (2 strains), 4a (2 strains), 4b (4 strains), 5a (5 strains) and 7 (1 strain), Cj serotypes TCK 9, 13, 26 (each 1 strain), 21 (2 strains) and untypable (8 strains) and 24 serotypes of Sal. Ye O3 and Yp were detected frequently in cold months. There was no definite seasonal variation of Ye O5,27 Cj and Sal in internal origin of dogs and cats. Ye O3, Yp and Cj were counted at 10(2) to 10(7) cells per g of the jejunal-to-rectal contents, but Sal at less than 10(2) cells per g of the intestinal contents. Ye O3, Yp and Sal were recovered from mesenteric lymph nodes, but not Ye O5,27 and Cj. PMID- 4096152 SO - Zentralbl Bakteriol Mikrobiol Hyg [B] 1985 Dec;181(3-5):430-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [86 medline neighbors] UI - 86101446 AU - Gonzalez HE AU - Crowell WA AU - Caudle AB AU - Thompson FN TI - Morphometric studies of the bovine uterus: microscopic lesions and retrospective reproductive history. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*pathology MH - Cervicitis/complications/pathology/veterinary MH - Endometritis/complications/pathology/veterinary MH - Female MH - Fertility MH - Infertility, Female/etiology/*veterinary MH - Leptospirosis/complications/veterinary MH - Uterine Diseases/complications/pathology/*veterinary MH - Uterus/*pathology PT - JOURNAL ARTICLE DA - 860219 DP - 1985 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2588-95 SB - M CY - UNITED STATES IP - 12 VI - 46 JC - 40C AA - Author EM - 8604 AB - A survey of reproductive tracts from nonpregnant cows at an abattoir was conducted. Reproductive tracts from 98 cows were studied microscopically and evaluated with a grading system to determine the severity of pathologic changes. Inflammatory reaction (type and distribution), fibrosis, gland morphology, and appearance were measured, quantified, and scored (1 to 4). Category 1 endometrium (normal) was found in 18 cows, category 2 in 23, category 3 in 34, and category 4 in 23. The category of endometrium was then compared with the retrospective reproductive status, and it was found that reproductive problems had occurred in 6 cows (33.3%) in category 1, in 13 cows (56.5%) in category 2, in 25 cows (73.5%) in category 3, and in 21 cows (91.3%) in category 4. Cervicitis was found in 43 (43.8%) genital tracts; 16 cows (16.3%) had salpingitis. Ovarian lesions were not observed. Serum samples were tested for certain antibodies. Only 1 was seropositive for brucellosis, but 61 of 81 sera had leptospira titers greater than 1:100 and 1:50 (hardjo). The serovar hardjo was the most prevalent. All sera had neutralizing titers against parainfluenza type 3 virus; 74.2% and 56.7% of the sera had neutralizing antibodies against bovine viral diarrhea virus and infectious bovine rhinotracheitis virus, respectively. PMID- 4083598 SO - Am J Vet Res 1985 Dec;46(12):2588-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 86101441 AU - Marcus LC AU - Patterson MM AU - Gilfillan RE AU - Urband PH TI - Antibodies to Borrelia burgdorferi in New England horses: serologic survey. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Borrelia/*immunology MH - Borrelia Infections/immunology/*veterinary MH - Horse Diseases/*immunology MH - Horses MH - New England MH - Support, U.S. Gov't, P.H.S. RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE ID - 2-507-RR05852-03/RR/NCRR DA - 860219 DP - 1985 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2570-1 SB - M CY - UNITED STATES IP - 12 VI - 46 JC - 40C AA - Author EM - 8604 AB - Twelve of 50 randomly selected horses from areas endemic for Borrelia burgdorferi had indirect fluorescent antibody titers of 1:8 to 1:2,048 against B burgdorferi. One of 50 horses from nonendemic areas had a titer of 1:8. This difference in the number of horses seropositive for B burgdorferi (P less than 0.002) and our finding that seropositive horses did not have agglutinating antibodies against potentially cross- reacting Leptospira spp indicated that horses in endemic areas were exposed to B burgdorferi and that the spirochete induced an antibody response in the horses. PMID- 4083595 CU - 96 SO - Am J Vet Res 1985 Dec;46(12):2570-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 86101429 AU - Tripathy DN AU - Hanson LE AU - Bedoya M AU - Mansfield ME TI - Experimental infection of pregnant and lactating goats with Leptospira interrogans serovars hardjo and szwajizak. LA - Eng MH - Animal MH - Female MH - Goats MH - Kidney/microbiology MH - Lactation MH - Leptospira interrogans/classification/isolation & purification MH - Liver/microbiology MH - Mammae/microbiology MH - Pregnancy MH - Pregnancy Complications, Infectious/*etiology/microbiology MH - Species Specificity MH - Support, U.S. Gov't, Non-P.H.S. MH - Weil's Disease/*complications/etiology/microbiology PT - JOURNAL ARTICLE DA - 860219 DP - 1985 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2515-8 SB - M CY - UNITED STATES IP - 12 VI - 46 JC - 40C AA - Author EM - 8604 AB - Pathogenesis of 2 Leptospira serovars, hardjo and szwajizak, was studied in pregnant and lactating goats. Although clinical signs of leptospiral infection were minimal, cultural isolations were made from the mammary gland of 2 goats and the kidney of 1 goat inoculated with serovar hardjo (C846). The isolations were made only on solid bovine albumin polysorbate-80 medium supplemented either with rabbit serum or sodium pyruvate. Cultural isolations of serovar szwajizak were made from kidney, liver, brain, urine, and mammary gland samples of 1 goat and the liver and kidney samples of its kids. These isolations were made in only the solid bovine albumin polysorbate-80 medium which had been supplemented with normal goat serum. PMID- 4083586 SO - Am J Vet Res 1985 Dec;46(12):2515-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 86101428 AU - Tripathy DN AU - Hanson LE AU - Mansfield ME AU - Thilsted JP TI - Experimental infection of lactating goats with Leptospira interrogans serovars pomona and hardjo. LA - Eng MH - Animal MH - Comparative Study MH - Female MH - Goats MH - Lactation MH - Leptospira interrogans/classification MH - Pregnancy MH - Pregnancy Complications, Infectious/*etiology MH - Species Specificity MH - Support, U.S. Gov't, Non-P.H.S. MH - Weil's Disease/diagnosis/etiology/*veterinary PT - JOURNAL ARTICLE DA - 860219 DP - 1985 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2512-4 SB - M CY - UNITED STATES IP - 12 VI - 46 JC - 40C AA - Author EM - 8604 AB - Pathogenesis of Leptospira interrogans serovars pomona and hardjo was evaluated in 14 lactating goats. Although mild clinical signs of leptospiral infection characterized by pyrexia and reduction in milk yield appeared in some animals, a consistent clinical pattern was not observed in the inoculated animals. The pomona serovar was isolated from the kidney of 1 of the 4 goats inoculated with serovar pomona. The hardjo serovar (strain UI 750) was isolated in the rabbit serum- supplemented bovine albumin polysorbate-80 liquid medium only from the mammary gland of 1 of 4 goats at 13 days after inoculation with serovar hardjo. The positive culture was detected after an 8-month incubation period. PMID- 4083585 SO - Am J Vet Res 1985 Dec;46(12):2512-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [96 medline neighbors] UI - 86085284 AU - Dierauf LA AU - Vandenbroek DJ AU - Roletto J AU - Koski M AU - Amaya L AU - Gage LJ TI - An epizootic of leptospirosis in California sea lions. LA - Eng MH - Animal MH - *Animals MH - *Animals, Wild MH - California MH - Disease Outbreaks/*veterinary MH - Female MH - Leptospirosis/diagnosis/drug therapy/*veterinary MH - Male MH - Penicillins/therapeutic use MH - *Pinnipedia MH - *Seals MH - Tetracycline/therapeutic use RN - 0 (Penicillins) RN - 60-54-8 (Tetracycline) PT - JOURNAL ARTICLE DA - 860131 DP - 1985 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1145-8 SB - M CY - UNITED STATES IP - 11 VI - 187 JC - HAV AA - Author EM - 8604 AB - Between May and December 1984, an epizootic of leptospirosis in California sea lions (Zalophus californianus) occurred along the west coast of the United States from Monterey County, Calif, northward to Seattle, Wash. Clinical signs observed were severe depression, excessive thirst, and tucked-up posturing, with associated leukocytosis and increased globulin, BUN, and creatinine values. Effective antibiotic therapy consisted of tetracycline (22 mg/kg of body weight every 8 hours, orally) or potassium penicillin G (44,000 U/kg every 12 hours, orally or IM) for 10 to 14 days. Sixty-six sea lions were treated successfully and released. Necropsies of animals that died indicated marked kidney swelling, darkened reniculi, and poorly differentiated cortices and medullae, thick, black bile in gallbladders, thick, pale yellow pericardial fluid, and friable hemorrhagic mesentery. Primary histologic lesions were tubular nephritis and glomerulonephritis. Darkfield microscopy of kidney macerates and/or urine, and results of the microscopic agglutination test, using Leptospira serovar pomona-killed antigen led to a presumptive diagnosis of leptospirosis. Bacteriologic isolation and identification is ongoing. The epizootic primarily affected juvenile or subadult male California sea lions migrating northward from breeding rookeries of southern California's Channel Islands. PMID- 4077625 CU - 92 SO - J Am Vet Med Assoc 1985 Dec 1;187(11):1145-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [97 medline neighbors] UI - 86085291 AU - Clark RK AU - Jessup DA AU - Kock MD AU - Weaver RA TI - Survey of desert bighorn sheep in California for exposure to selected infectious diseases. LA - Eng MH - Animal MH - *Animals MH - *Animals, Wild MH - California MH - Communicable Diseases/epidemiology/*veterinary MH - Cross-Sectional Studies MH - *Desert Climate MH - Female MH - Male MH - Sheep MH - Sheep Diseases/*epidemiology MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 860131 DP - 1985 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1175-9 SB - M CY - UNITED STATES IP - 11 VI - 187 JC - HAV AA - Author EM - 8604 AB - From February 1983 to June 1985, 188 desert bighorn sheep (Ovis canadensis nelsoni, = 161 and Oc cremnobates, = 27) from 18 herds in 17 mountain ranges and one captive herd were caught, marked, and had blood, fecal, and nasal mucus samples collected. Nasal swab specimens were cultured bacteriologically and virologically specifically for parainfluenza-3 (PI-3) virus. Bacterial flora differed from herd to herd. Pathogenic pneumophilic bacteria (eg, Pasteurella sp) seldom were found. Parainfluenza-3 virus was isolated from 6 bighorn sheep in 3 herds. Fecal specimens were examined for parasite ova and low numbers of lungworm (Protostrongylus sp) larvae were found in feces from 2 herds. Sera were evaluated for antibodies against respiratory syncytial virus, ovine progressive pneumonia, infectious bovine rhinotracheitis, PI-3, bovine viral diarrhea, brucellosis, leptospirosis, contagious ecthyma, bluetongue, and epizootic hemorrhagic disease. Blood clots were cultured virologically for bluetongue and epizootic hemorrhagic disease. Serologic evidence of bluetongue and/or epizootic hemorrhagic disease was found in 9 herds, and bluetongue virus (serotypes 10,11,13 and 17) was isolated from 3 herds. Antibody titers against PI-3 and respiratory syncytial virus were found in 9 and 13 herds, respectively. Evidence of bovine viral diarrhea infection was found in 6 herds, whereas infectious bovine rhinotracheitis was found in only 1 herd. Antibody titers against contagious ecthyma were found in 9 of 18 herds in California, and active lesions were seen occasionally. Evidence of ovine progressive pneumonia, leptospirosis, or brucellosis was not found. PMID- 3878356 CU - 90 SO - J Am Vet Med Assoc 1985 Dec 1;187(11):1175-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 86289941 AU - Bao L AU - Dai BM TI - [Studies on the structural and functional changes in the pulmonary microvessels in pulmonary diffuse hemorrhage in leptospirosis] LA - Chi MH - Animal MH - Capillaries/ultrastructure MH - English Abstract MH - Guinea Pigs MH - Hemorrhage MH - Lung/*blood supply/ultrastructure MH - Lung Diseases/*pathology MH - Male MH - Microcirculation/ultrastructure MH - Microscopy, Electron MH - Support, Non-U.S. Gov't MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 860925 DP - 1985 Dec IS - 0253-4290 TA - Ssu Chuan I Hsueh Yuan Hsueh Pao PG - 285-8 CY - CHINA IP - 4 VI - 16 JC - VBT EM - 8611 PMID- 3837387 EA - A SO - Ssu Chuan I Hsueh Yuan Hsueh Pao 1985 Dec;16(4):285-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 86124140 AU - Myers DM AU - Ruiz A AU - Applewhaite L TI - Leptospiral agglutinins among cattle in the Republic of Guyana. LA - Eng MH - Agglutinins/*analysis MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*immunology MH - Guyana MH - Leptospira/immunology MH - Leptospirosis/immunology/*veterinary RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860228 DP - 1985 Nov IS - 0049-4747 TA - Trop Anim Health Prod PG - 239-43 SB - M CY - SCOTLAND IP - 4 VI - 17 JC - WG2 AA - Author EM - 8605 AB - Cattle sera collected in the Republic of Guyana during 1981 to 1982 were examined for serologic evidence of leptospirosis. Significant leptospiral agglutinins (1:100 or higher) were disclosed in 49.1% of 2,935 apparently normal cattle from 734 farms in the three major cattle- raising regions of the country. Seroreactions principally involved hardjo and wolffi of the Sejroe serogroup, icterohaemorrhagiae, pomona, tarassovi, canicola and grippotyphosa. A high proportion of reactions to one or more of different leptospiral serovars were observed in each of the three regions. These variations were attributed to differences in environmental conditions and farming practices. The findings provided evidence for the first time of the widespread occurrence of leptospirosis in cattle in Guyana caused by multiple leptospiral serovars. PMID- 4089971 CU - 91 SO - Trop Anim Health Prod 1985 Nov;17(4):239-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 86098549 AU - Parma AE AU - Santisteban CG AU - Villalba JS AU - Bowden RA TI - Experimental demonstration of an antigenic relationship between Leptospira and equine cornea. LA - Eng MH - Animal MH - Antigens/*immunology MH - Antigens, Bacterial/immunology MH - Cornea/*immunology MH - Corneal Opacity/etiology/veterinary MH - Cross Reactions MH - Female MH - Horse Diseases/etiology MH - Horses MH - Leptospira interrogans/*immunology MH - Leptospirosis/complications/veterinary MH - Male MH - Support, Non-U.S. Gov't RN - 0 (Antigens) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 860214 DP - 1985 Nov IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 215-24 SB - M CY - NETHERLANDS IP - 2-3 VI - 10 JC - XCB AA - Author EM - 8604 AB - Horses inoculated with either equine cornea or killed Leptospira interrogans serovars pomona, tarassovi, icterohaemorrhagiae, wolffi and hardjo, developed corneal opacity and produced antibodies which made it possible to demonstrate partial antigenic identity between equine cornea and four of those serovars employed. These antibodies were isolated by means of immunoadsorptions, purified by ion-exchange chromatography (DEAE-Sephadex A-50) and run by immuno-electrophoresis in agar gel. Both antibodies, anti-equine cornea and anti-leptospira, showed that they corresponded to the IgGb subclass. They bound themselves to equine cornea in vivo and in vitro as was proved by immunofluorescence. This antigenic relationship may be in part responsible for pathogenesis of corneal opacity in leptospirosis of horses. PMID- 4082476 CU - 91 SO - Vet Immunol Immunopathol 1985 Nov;10(2-3):215-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 86095809 AU - Ellis WA AU - O'Brien JJ AU - Cassells JA AU - Neill SD AU - Hanna J TI - Excretion of Leptospira interrogans serovar hardjo following calving or abortion. LA - Eng MH - Abortion, Veterinary/etiology/microbiology MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Leptospira interrogans/*isolation & purification MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/*veterinary MH - Vagina/*microbiology MH - Weil's Disease/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 860217 DP - 1985 Nov IS - 0034-5288 TA - Res Vet Sci PG - 296-8 SB - M CY - ENGLAND IP - 3 VI - 39 JC - R7D AA - Author EM - 8604 AB - Leptospira interrogans serovar hardjo was demonstrated in the vaginal discharges of 12 experimentally infected heifers for up to eight days after abortion or calving. Organisms were recovered from the oviducts of heifers examined at slaughter eight to 22 days after calving or 32 to 91 days after infection. They were also recovered from the uteri of four heifers eight to 22 days after calving. PMID- 4081333 SO - Res Vet Sci 1985 Nov;39(3):296-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 86027550 AU - Kingscote BF TI - Leptospirosis in two veterinarians. LA - Eng MH - Animal MH - Case Report MH - Diagnosis, Differential MH - Female MH - Human MH - Hydrocortisone/analogs & derivatives/therapeutic use MH - Leptospira interrogans MH - Leptospirosis/*diagnosis/drug therapy MH - Male MH - Occupational Diseases/*diagnosis/drug therapy MH - Penicillin G/therapeutic use MH - Tetracycline/therapeutic use MH - *Veterinary Medicine MH - Zoonoses RN - 2203-97-6 (cortisol succinate) RN - 50-23-7 (Hydrocortisone) RN - 60-54-8 (Tetracycline) RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 851209 DP - 1985 Nov 1 IS - 0008-4409 TA - Can Med Assoc J PG - 879-80 SB - A SB - M SB - X CY - CANADA IP - 9 VI - 133 JC - CKW EM - 8602 PMID- 4052899 SO - Can Med Assoc J 1985 Nov 1;133(9):879-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 86022796 AU - Wiesenthal AM AU - Ressman M AU - Caston SA AU - Todd JK TI - Toxic shock syndrome. I. Clinical exclusion of other syndromes by strict and screening definitions. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Diagnosis, Differential MH - False Positive Reactions MH - Female MH - Human MH - Infant MH - Male MH - Medical Records MH - Middle Age MH - Retrospective Studies MH - Septicemia/diagnosis MH - Shock, Septic/*diagnosis/physiopathology MH - Staphylococcal Infections/diagnosis MH - Staphylococcus aureus/isolation & purification MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 851107 DP - 1985 Nov IS - 0002-9262 TA - Am J Epidemiol PG - 847-56 SB - M SB - X CY - UNITED STATES IP - 5 VI - 122 JC - 3H3 AA - Author EM - 8601 AB - Several clinical definitions of toxic shock syndrome have been proposed and used in extensive epidemiologic and clinical studies. Most of these definitions suggest (but usually do not require) that there be sufficient laboratory studies to exclude other potentially similar syndromes. Simplified definitions which broaden the spectrum of toxic shock syndrome illness have also been proposed but not validated. In this study, clinical findings of consecutive hospitalized patients were compared: nine with toxic shock syndrome (confirmed by a modification of the collaborative strict case definition) and 120 with potentially similar diagnoses (bacteremia with shock, meningococcemia, Staphylococcus aureus bacteremia, scarlet fever, toxic epidermal necrolysis, acute rheumatic fever, leptospirosis, Rocky Mountain spotted fever, rubeola, Kawasaki syndrome, erythema multiforme, and Stevens-Johnson syndrome). None of the 120 controls satisfied the clinical criteria of the modified strict definition of toxic shock syndrome, demonstrating its exclusionary properties even in the absence of additional laboratory data. A "simplified" screening definition was constructed which might be applied early in illness (i.e., at admission) and this definition distinguished all the patients with toxic shock syndrome from all but three (2.5%) of the 117 analyzable patients with other mucocutaneous or potential infectious shock syndromes. Applied prospectively in the state of Colorado passive/active reporting system, the screening definition identified 24 potential toxic shock syndrome cases of which 19 (76%) eventually were confirmed as toxic shock syndrome. Before being adopted and widely used, clinical syndrome definitions should be documented to exclude other potentially overlapping syndromes or should require additional mandatory exclusionary laboratory data. PMID- 4050773 SO - Am J Epidemiol 1985 Nov;122(5):847-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 86118109 AU - Kriuchechnikov VN AU - Korenberg EI AU - Shcherbakov SV AU - Kalinin AA AU - Amridinov KN TI - [Basis for the possible use of the indirect immunofluorescence reaction for the serological diagnosis of tick-borne borreliosis] LA - Rus MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/immunology MH - *Arachnid Vectors MH - Borrelia/immunology MH - Borrelia Infections/*diagnosis MH - Comparative Study MH - Cross Reactions MH - English Abstract MH - Evaluation Studies MH - Fluorescent Antibody Technique MH - Human MH - Leishmania donovani/immunology MH - Leptospira/immunology MH - Serodiagnosis/methods MH - *Ticks RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 860304 DP - 1985 Nov-Dec IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 39-43 CY - USSR IP - 6 JC - M72 EM - 8605 PMID- 3911041 CU - 91 TT - Obosnovanie vozmozhnosti primeneniia nepriamoi reaktsii immunofliuorestsentsii dlia serologicheskoi diagnostiki kleshchevykh borreliozov. EA - A SO - Med Parazitol (Mosk) 1985 Nov-Dec;(6):39-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 86208453 AU - Floch JJ AU - Gras C AU - Lecamus JL TI - [Leptospirosis] LA - Fre MH - Animal MH - Disease Reservoirs MH - Health Education MH - Human MH - *Leptospirosis/prevention & control/transmission MH - Penicillins/therapeutic use MH - Zoonoses RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 860523 DP - 1985 Nov-Dec IS - 0222-9307 TA - Soins Pathol Trop PG - 3-8 SB - N CY - FRANCE IP - 56 JC - UVM EM - 8608 PMID- 3854711 CU - 92 LI - N TT - Les leptospiroses. SO - Soins Pathol Trop 1985 Nov-Dec;(56):3-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 86085610 AU - Heidt GA AU - Harger C AU - Harger H AU - McChesney TC TI - Serological study of selected disease antibodies in Arkansas--furbearer trappers, a high risk group. LA - Eng MH - Antibodies/*analysis MH - Antibodies, Bacterial/*analysis MH - Arkansas MH - Female MH - Human MH - Leptospirosis/*immunology MH - Male MH - Occupational Diseases/*immunology MH - Risk MH - Rocky Mountain Spotted Fever/*immunology MH - Support, Non-U.S. Gov't MH - Toxoplasmosis/*immunology MH - Tularemia/*immunology RN - 0 (Antibodies) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860131 DP - 1985 Nov IS - 0004-1858 TA - J Ark Med Soc PG - 265-9 CY - UNITED STATES IP - 6 VI - 82 JC - HEV EM - 8604 PMID- 2934372 CU - 92 SO - J Ark Med Soc 1985 Nov;82(6):265-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 86095808 AU - Ellis WA AU - Montgomery J AU - Cassells JA TI - Dihydrostreptomycin treatment of bovine carriers of Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Carrier State/drug therapy/*veterinary MH - Cattle MH - Cattle Diseases/*drug therapy/microbiology MH - Dihydrostreptomycin Sulfate/*therapeutic use MH - Female MH - Genital Diseases, Female/drug therapy/veterinary MH - Kidney Diseases/drug therapy/veterinary MH - Weil's Disease/drug therapy/*veterinary RN - 5490-27-7 (Dihydrostreptomycin Sulfate) PT - JOURNAL ARTICLE DA - 860217 DP - 1985 Nov IS - 0034-5288 TA - Res Vet Sci PG - 292-5 SB - M CY - ENGLAND IP - 3 VI - 39 JC - R7D AA - Author EM - 8604 AB - Ten non-pregnant heifers, experimentally infected with Leptospira interrogans serovar hardjo, were each given an intramuscular injection of dihydrostreptomycin at a dose rate of 25 mg kg-1. In five of these animals this treatment was repeated after 14 days. Treatment failed to remove established genital or renal infection in seven of the 10 heifers, although the number of organisms persisting was apparently reduced in these animals. Serovar hardjo infection persisted for at least 83 days in the oviduct and uterus and these tissues may be as important carrier sites for serovar hardjo as bovine kidney tissue. PMID- 2417297 CU - 95 SO - Res Vet Sci 1985 Nov;39(3):292-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [40 medline neighbors] UI - 86014242 AU - Elliot DL AU - Tolle SW AU - Goldberg L AU - Miller JB TI - Pet-associated illness. LA - Eng MH - Animal MH - *Animals, Domestic/microbiology/parasitology MH - Bites and Stings/microbiology MH - Brucellosis/transmission MH - Campylobacter Infections/transmission MH - Cat-Scratch Disease/transmission MH - Cats MH - Cestode Infections/transmission MH - Dermatomycoses/transmission MH - Dirofilariasis/transmission MH - Dog Diseases/transmission MH - Dogs MH - Echinococcosis/transmission MH - Female MH - Human MH - Infant, Newborn MH - Larva Migrans/transmission MH - Larva Migrans, Visceral/transmission MH - Leptospirosis/transmission MH - Plague/transmission MH - Pregnancy MH - Rabbits MH - Rabies/transmission MH - Rickettsiaceae Infections/transmission MH - Salmonella Infections/transmission MH - Toxoplasmosis/transmission MH - Tularemia/transmission MH - *Zoonoses PT - JOURNAL ARTICLE PT - REVIEW DA - 851030 DP - 1985 Oct 17 IS - 0028-4793 TA - N Engl J Med PG - 985-95 SB - A SB - M SB - X CY - UNITED STATES IP - 16 VI - 313 JC - NOW EM - 8601 RF - 164 PMID- 3900726 CU - 90 SO - N Engl J Med 1985 Oct 17;313(16):985-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85300534 AU - Lane RS AU - Burgdorfer W AU - Hayes SF AU - Barbour AG TI - Isolation of a spirochete from the soft tick, Ornithodoros coriaceus: a possible agent of epizootic bovine abortion. LA - Eng MH - Abortion, Veterinary/*etiology/parasitology MH - Animal MH - Cattle MH - Cattle Diseases/*etiology/parasitology MH - Electrophoresis, Polyacrylamide Gel MH - Female MH - Fluorescent Antibody Technique MH - Male MH - Microscopy, Electron MH - Pregnancy MH - Spirochaeta/*isolation & purification MH - Support, U.S. Gov't, P.H.S. MH - Ticks/*microbiology PT - JOURNAL ARTICLE ID - 2-S07-RR07006/RR/NCRR DA - 851022 DP - 1985 Oct 4 IS - 0036-8075 TA - Science PG - 85-7 SB - M SB - X CY - UNITED STATES IP - 4721 VI - 230 JC - UJ7 AA - Author EM - 8512 AB - A Borrelia-like spirochete was detected in all three parasitic stages of Ornithodoros coriaceus, the soft tick implicated in the epizoology of epizootic bovine abortion. After the spirochete had been isolated, its distinctness from other North American tick-borne borreliae as well as from Spirochaeta aurantia, Treponema pallidum, and Leptospira interrogans serovar pomona was established on the basis of its morphology, protein components, and inability to infect mice. The spirochete is passed trans-stadially and via eggs by ticks, and it is also excreted in coxal fluid after ticks have fed and detached. Circumstantial evidence suggests that the spirochete may be causally related to epizootic bovine abortion. RO - M:BDS PMID- 3898367 LR - 860116 CU - 96 SO - Science 1985 Oct 4;230(4721):85-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 86150895 AU - Zavala-Velazquez J AU - Sosa-Leal J AU - Barrera Perez MA AU - Bolio-Cicero A AU - Laviada-Arrigunaga FA TI - [Human leptospirosis in Yucatan. Presentation of 2 new cases and clinical review] LA - Spa MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Animals, Domestic MH - Case Report MH - English Abstract MH - Human MH - Leptospirosis/complications/epidemiology/*pathology MH - Male MH - Mexico MH - Middle Age MH - Weil's Disease/etiology MH - Zoonoses/epidemiology/pathology PT - JOURNAL ARTICLE DA - 860331 DP - 1985 Oct-Dec IS - 0034-8376 TA - Rev Invest Clin PG - 353-7 CY - MEXICO IP - 4 VI - 37 JC - SCH EM - 8606 PMID- 4095400 CU - 88 TT - Leptospirosis humana en Yucatan. Presentacion de dos nuevos casos y revision clinica. EA - A SO - Rev Invest Clin 1985 Oct-Dec;37(4):353-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 86102991 AU - Ketterer PJ AU - Dunster PJ TI - Failure to eliminate Leptospira pomona from pigs by treatment with long acting oxytetracyline. LA - Eng MH - Animal MH - Kidney/microbiology MH - Leptospira/drug effects MH - Leptospirosis/prevention & control/*veterinary MH - Oxytetracycline/*therapeutic use MH - Swine MH - Swine Diseases/microbiology/*prevention & control RN - 79-57-2 (Oxytetracycline) PT - JOURNAL ARTICLE DA - 860213 DP - 1985 Oct IS - 0005-0423 TA - Aust Vet J PG - 348-9 SB - M CY - AUSTRALIA IP - 10 VI - 62 JC - 9IE EM - 8604 PMID- 4084154 SO - Aust Vet J 1985 Oct;62(10):348-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 86102989 AU - Mitchell G AU - Leonard J TI - Leptospira interrogans serovar hardjo infection in a sheep. LA - Eng MH - Animal MH - Case Report MH - Female MH - Kidney/microbiology MH - Leptospira interrogans/isolation & purification MH - Sheep MH - Sheep Diseases/*microbiology MH - Weil's Disease/*veterinary PT - JOURNAL ARTICLE DA - 860213 DP - 1985 Oct IS - 0005-0423 TA - Aust Vet J PG - 346-7 SB - M CY - AUSTRALIA IP - 10 VI - 62 JC - 9IE EM - 8604 PMID- 4084152 SO - Aust Vet J 1985 Oct;62(10):346-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 86090196 AU - Klishevich BA AU - Asauliuk IK AU - Sidorenko SI TI - [Pulmonary syndrome in leptospirosis] LA - Rus MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Human MH - Male MH - Pneumonia/diagnosis/*etiology MH - Weil's Disease/*complications/diagnosis PT - JOURNAL ARTICLE DA - 860205 DP - 1985 Oct IS - 0023-2149 TA - Klin Med (Mosk) PG - 129-32 CY - USSR IP - 10 VI - 63 JC - KW2 EM - 8604 PMID- 4079288 TT - O legochnom sindrome pri leptospiroze. SO - Klin Med (Mosk) 1985 Oct;63(10):129-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 86086273 AU - Milner AR AU - Jackson KB AU - Woodruff K AU - Smart IJ TI - Enzyme-linked immunosorbent assay for determining specific immunoglobulin M in infections caused by Leptospira interrogans serovar hardjo. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Evaluation Studies MH - Human MH - IgM/*analysis MH - Leptospira interrogans/*immunology MH - Weil's Disease/*diagnosis/immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860130 DP - 1985 Oct IS - 0095-1137 TA - J Clin Microbiol PG - 539-42 SB - M CY - UNITED STATES IP - 4 VI - 22 JC - HSH AA - Author EM - 8604 AB - An automated enzyme-linked immunosorbent assay detecting specific immunoglobulin M in infections with Leptospira interrogans serovar hardjo was evaluated on 69 patients. The test was sensitive and simple to perform, requiring a single dilution of test serum, with data expressed as units of antibody activity interpolated from a reference serum pool. PMID- 4077964 CU - 91 SO - J Clin Microbiol 1985 Oct;22(4):539-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 86060801 AU - Waitkins SA AU - Wanyangu S AU - Palmer M TI - The coypu as a rodent reservoir of leptospira infection in Great Britain. LA - Eng MH - Animal MH - Complement Fixation Tests MH - *Disease Reservoirs MH - Female MH - Great Britain MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*transmission MH - Male MH - Rodentia/*microbiology PT - JOURNAL ARTICLE DA - 860106 DP - 1985 Oct IS - 0022-1724 TA - J Hyg (Lond) PG - 409-17 SB - M CY - ENGLAND IP - 2 VI - 95 JC - IEF AA - Author EM - 8603 AB - The coypu (Myocastor coypus Molina) is an aquatic rodent that has become a widespread pest in the south-east of England. Since the natural habitat of this animal is aquatic, the possibility of infection with leptospires was investigated. Twenty-nine coypu were trapped and examined by serological, histological and cultural methods. Of these, there was serological evidence of infection in seven coypus and Leptospira interrogans var. Wolffii was isolated from a further animal. This appears to be the first report of the isolation of leptospira from a coypu in Great Britain. PMID- 4067296 SO - J Hyg (Lond) 1985 Oct;95(2):409-17 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 86041588 AU - Estavoyer JM AU - Ottignon Y AU - Stimmesse B AU - Cardot N AU - Boillot A AU - Couetdic G TI - [Demonstration of lipoprotein anomalies in leptospirosis. Prospective study in 10 patients] LA - Fre MH - Adolescence MH - Adult MH - English Abstract MH - Hospitalization MH - Human MH - Leptospirosis/*blood MH - Lipoproteins/*blood/metabolism MH - Lipoproteins, HDL/blood MH - Lipoproteins, LDL/blood MH - Lipoproteins, VLDL/blood MH - Liver/metabolism MH - Male MH - Middle Age MH - Prospective Studies MH - Time Factors RN - 0 (Lipoproteins) RN - 0 (Lipoproteins, HDL) RN - 0 (Lipoproteins, VLDL) PT - JOURNAL ARTICLE DA - 851218 DP - 1985 Oct IS - 0369-8114 TA - Pathol Biol (Paris) PG - 819-23 SB - M CY - FRANCE IP - 8 VI - 33 JC - OSG AA - Author EM - 8602 AB - Abnormalities of lipid metabolism have never been shown in human leptospirosis. A prospective study of plasma lipids was performed in 10 consecutive patients with leptospirosis. Significant increase of triglycerides with low levels of the high-density lipoproteins and cholesterol fraction was observed in 8 patients. Electrophoresis of lipoproteins showed a fusion of beta and pre-beta lipoproteins and a marked decrease of alpha lipoproteins. The respective role of bacteria, liver and kidney could be suggested to explain these abnormalities of lipoproteins in leptospirosis. PMID- 3903619 CU - 92 TT - Mise en evidence d'anomalies des lipoproteines au cours des leptospiroses. Etude prospective chez dix malades. EA - A SO - Pathol Biol (Paris) 1985 Oct;33(8):819-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 86054904 AU - Halliwell RE AU - Brim TA AU - Hines MT AU - Wolf D AU - White FH TI - Studies on equine recurrent uveitis. II: The role of infection with Leptospira interrogans serovar pomona. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Anti-Idiotypic/analysis/biosynthesis MH - Aqueous Humor/immunology MH - Enzyme-Linked Immunosorbent Assay MH - Eye/immunology MH - *Horse Diseases MH - Horses MH - IgG/immunology MH - IgM/immunology MH - Leptospira interrogans/immunology MH - Recurrence MH - Support, U.S. Gov't, P.H.S. MH - Uveitis/etiology/*veterinary MH - *Weil's Disease RN - 0 (Antibodies, Anti-Idiotypic) PT - JOURNAL ARTICLE ID - 5 R01 EY04018/EY/NEI DA - 851224 DP - 1985 Oct IS - 0271-3683 TA - Curr Eye Res PG - 1033-40 SB - M CY - ENGLAND IP - 10 VI - 4 JC - DUB AA - Author EM - 8603 AB - An enzyme linked immunosorbent assay was developed for the detection of immunoglobulin class specific antibodies to Leptospira interrogans serovar pomona in the serum and aqueous humor of horses. Serum antibody was also assayed by microscopic agglutination tests. Although higher levels of antibody were found in sera from horses with signs of uveitis, the association was not statistically significant. Antibodies to pomona were detected in the aqueous of 12 eyes from the 101 horses sampled at a slaughterhouse, and in most instances, a comparison of the aqueous/serum antibody level with that of the total aqueous/serum IgG level indicated intraocular antibody synthesis. Antibodies were also found in 4 aqueous (or vitreous) samples out of 9 obtained from horses with clinically documented uveitis and the above comparison again indicated intraocular antibody synthesis. The data point to an important role for pomona as an etiology of equine recurrent uveitis but also emphasize that the initiating cause for this disease is often obscure in that association with leptospirosis cannot be shown in many instances. PMID- 3877614 CU - 96 SO - Curr Eye Res 1985 Oct;4(10):1033-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 86086286 AU - Le Febvre RB AU - Foley JW AU - Thiermann AB TI - Rapid and simplified protocol for isolation and characterization of leptospiral chromosomal DNA for taxonomy and diagnosis. LA - Eng MH - Chromosomes, Bacterial MH - DNA Restriction Enzymes MH - DNA, Bacterial/analysis/*isolation & purification MH - Leptospira interrogans/classification/growth & development/*genetics MH - Ultracentrifugation RN - EC 3.1.21 (DNA Restriction Enzymes) RN - EC 3.1.21.- (Deoxyribonuclease EcoRI) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 860130 DP - 1985 Oct IS - 0095-1137 TA - J Clin Microbiol PG - 606-8 SB - M CY - UNITED STATES IP - 4 VI - 22 JC - HSH AA - Author EM - 8604 AB - We have developed a rapid method for the isolation of leptospiral chromosomal DNA which yields DNA of a purity suitable for restriction endonuclease analysis. A small volume (15 to 20 ml) of an exponentially growing culture of leptospires yielded 2 to 4 micrograms of chromosomal DNA. In a 1-day protocol, the DNA was isolated, restricted with endonucleases, and fractionated on an agarose gel. Chromosomal DNA from dinger zones (visible subsurface zones of leptospiral growth) of first semisolid subcultures of field isolates was also isolated and characterized, thus greatly speeding up the diagnostic process. PMID- 3001135 CU - 93 SO - J Clin Microbiol 1985 Oct;22(4):606-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 86045774 AU - Broughton ES AU - Scarnell J TI - Prevention of renal carriage of leptospirosis in dogs by vaccination. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Dog Diseases/immunology/*prevention & control/transmission MH - Dogs MH - *Immunization MH - Kidney/microbiology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/prevention & control/transmission/*veterinary RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 851216 DP - 1985 Sep 21 IS - 0042-4900 TA - Vet Rec PG - 307-11 SB - M CY - ENGLAND IP - 12 VI - 117 JC - XBS AA - Author EM - 8602 AB - Dogs vaccinated with a Leptospira interrogans vaccine containing serogroups Canicola and Icterohaemorrhagiae and prepared from cultures grown in a protein-free medium resisted challenge with heterologous representatives of these serogroups. In contrast, control dogs were pyrexic and leptospires were isolated from the blood for nine days following Canicola challenge and six days after Icterohaemorrhagiae challenge. Leptospires were isolated from the urine of controls throughout the post challenge period and from kidneys at post mortem examination of six out of six and four out of six Canicola and Icterohaemorrhagiae challenged controls, respectively. There have been no reports of hypersensitivity reactions to this vaccine since its introduction in 1980. PMID- 4060538 CU - 91 SO - Vet Rec 1985 Sep 21;117(12):307-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 86135057 AU - Wang RF TI - [A 1:R matched case-control method for the study of cerebroarteritis etiology] LA - Chi MH - Arteritis/*etiology MH - Cerebral Artery Diseases/*etiology MH - English Abstract MH - Epidemiologic Methods MH - Human MH - Leptospirosis/complications PT - JOURNAL ARTICLE DA - 860415 DP - 1985 Sep IS - 0253-9624 TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 285-7 CY - CHINA IP - 5 VI - 19 JC - D74 EM - 8606 PMID- 4092523 EA - A SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1985 Sep;19(5):285-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 86093633 AU - Sandstedt K AU - Engvall A TI - Serum antibodies to Leptospira bratislava in Swedish pigs and horses. LA - Eng MH - Animal MH - Antibodies, Bacterial/*isolation & purification MH - Female MH - Horses/*immunology MH - Leptospira/*immunology MH - Male MH - Support, Non-U.S. Gov't MH - Sweden MH - Swine/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860217 DP - 1985 Sep-Oct IS - 0029-1579 TA - Nord Vet Med PG - 312-3 SB - M CY - DENMARK IP - 5 VI - 37 JC - O4Z AA - Author EM - 8604 AB - Sera from 116 and 89 Swedish pigs and horses respectively were examined for the presence of antibodies to L. bratislava. Antibodies were found in 18.1 and 49.4% respectively of pigs and horses examined. Presence of serum antibodies was not associated with clinical signs of infection. PMID- 4080537 CU - 91 SO - Nord Vet Med 1985 Sep-Oct;37(5):312-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 86076866 AU - Batza HJ AU - Zettl K TI - [Demonstration of Leptospira antibodies in sheep sera using various serological methods] LA - Ger MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Complement Fixation Tests/veterinary MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Germany, West MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/*veterinary MH - Sheep MH - Sheep Diseases/*diagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860116 DP - 1985 Sep 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 307-11 CY - GERMANY, WEST IP - 9 VI - 98 JC - 9Q8 EM - 8603 PMID- 4074321 CU - 91 TT - Nachweis von Leptospiren-Antikorpern in Schafseren mittels verschiedener serologischer Methoden. EA - A SO - Berl Munch Tierarztl Wochenschr 1985 Sep 1;98(9):307-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 86076705 AU - Schandevyl P AU - Deleu D TI - Diseases and parasites of cattle in Vanuatu. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology/therapy MH - Parasitic Diseases/epidemiology/therapy/*veterinary MH - Support, Non-U.S. Gov't MH - Tuberculosis/epidemiology/therapy/veterinary PT - JOURNAL ARTICLE DA - 860108 DP - 1985 Sep IS - 0005-0423 TA - Aust Vet J PG - 297-300 SB - M CY - AUSTRALIA IP - 9 VI - 62 JC - 9IE AA - Author EM - 8603 AB - A study of cattle diseases was carried out in Vanuatu from 1971 to 1981. Tuberculosis was discovered in 4 herds and eradication was completed by 1981. The number of farms with brucellosis reactors increased from 2 in 1976 to 7 in 1978 despite eradication measures. Antibodies to serovars Leptospira icterohaemorrhagiae, australis, sejroe and canicola were demonstrated by the microscopic agglutination test. Antibodies were demonstrated against infectious bovine rhinotracheitis/infectious pustular vulvovaginitis and bovine virus diarrhoea/mucosal disease complexes. Of the 18 parasites identified, Haemaphysalis longicornis, Haemonchus, sp, Oesophagostomum phlebotomum and Neoascaris vitulorum were the most prevalent. As brucelossis is the only serious disease present, Vanuatu is in a favourable situation with regard to cattle diseases. PMID- 4074215 CU - 88 SO - Aust Vet J 1985 Sep;62(9):297-300 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [74 medline neighbors] UI - 85276882 AU - Demers RY AU - Frank R AU - Demers P AU - Clay M TI - Leptospiral exposure in Detroit rodent control workers. LA - Eng MH - Adult MH - Aged MH - Animal MH - Comparative Study MH - Epidemiologic Methods MH - Female MH - Human MH - Leptospira interrogans/*immunology MH - Leptospirosis/*immunology MH - Male MH - Michigan MH - Middle Age MH - Occupational Diseases/*immunology MH - Rats MH - *Rodent Control MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 850917 DP - 1985 Sep IS - 0090-0036 TA - Am J Public Health PG - 1090-1 SB - A SB - M CY - UNITED STATES IP - 9 VI - 75 JC - 3XW AA - Author EM - 8511 AB - Antibody levels to L. icterohemorrhagiae of rodent control workers and two control groups were compared with antibodies against five other leptospiral serotypes carried predominantly by species other than rats. Rodent control workers contact urban rats, 77 per cent of which are carriers of leptospiral organisms. Rodent control workers had higher antibody levels against L. icterohemorrhagiae than control groups (OR 4.37, 99 per cent CI = 3.0, 6.3 and OR 11.08, 99 per cent CI = 5.6, 22). Antibodies against the other five serotypes were almost non- existent in the study group. PMID- 4025662 SO - Am J Public Health 1985 Sep;75(9):1090-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 87093309 AU - Garcia MJ AU - Cornide RI AU - Gonzalez A TI - [Isolation of Leptospira in conventional animals, Mus musculus (albino variety) obtained from a traditional breeding center] LA - Spa MH - Animal MH - Animal Husbandry MH - Animals, Laboratory/*microbiology MH - Cuba MH - English Abstract MH - Female MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Male MH - Mice/*microbiology MH - Rodent Diseases/epidemiology/*microbiology PT - JOURNAL ARTICLE DA - 870128 DP - 1985 Sep-Dec IS - 0375-0760 TA - Rev Cubana Med Trop PG - 341-7 CY - CUBA IP - 3 VI - 37 JC - RPX EM - 8704 RO - M:STD PMID- 3916258 LR - 920817 CU - 90 TT - Aislamiento de leptospira en animales convencionales, Mus musculus (variedad albina) procedentes de un centro de cria tradicional. EA - A SO - Rev Cubana Med Trop 1985 Sep-Dec;37(3):341-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 86289927 AU - Peng HR AU - Dai BM TI - [A study of freeze replica and SEM on the hepatocytic tight junctions and canaliculi in the guinea pig with Leptospirosis icterohaemorrhagiae] LA - Chi MH - Animal MH - Bile Canaliculi/*ultrastructure MH - Bile Ducts, Intrahepatic/*ultrastructure MH - English Abstract MH - Frozen Sections MH - Guinea Pigs MH - Intercellular Junctions/*ultrastructure MH - Jaundice/pathology MH - Liver/*ultrastructure MH - Microscopy, Electron, Scanning MH - Support, Non-U.S. Gov't MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 860917 DP - 1985 Sep IS - 0253-4290 TA - Ssu Chuan I Hsueh Yuan Hsueh Pao PG - 225-9 CY - CHINA IP - 3 VI - 16 JC - VBT EM - 8611 PMID- 3837375 CU - 90 EA - A SO - Ssu Chuan I Hsueh Yuan Hsueh Pao 1985 Sep;16(3):225-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [57 medline neighbors] UI - 86289926 AU - Zhao SM AU - Dai BM AU - Wang YP AU - Tang XJ TI - [A study of the relationship between leptospiral virulence and adherence] LA - Chi MH - Adhesiveness MH - Animal MH - English Abstract MH - Fetus MH - Fibroblasts MH - Human MH - Leptospira/physiology/*pathogenicity MH - Leptospira interrogans/physiology/pathogenicity MH - Lung/cytology MH - Mice MH - Support, Non-U.S. Gov't MH - Virulence PT - JOURNAL ARTICLE DA - 860917 DP - 1985 Sep IS - 0253-4290 TA - Ssu Chuan I Hsueh Yuan Hsueh Pao PG - 221-4 CY - CHINA IP - 3 VI - 16 JC - VBT EM - 8611 PMID- 3837374 EA - A SO - Ssu Chuan I Hsueh Yuan Hsueh Pao 1985 Sep;16(3):221-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 86289917 AU - Wang CX AU - Ye DN AU - Bao L AU - Yan RH AU - Dai BM AU - Lei YD AU - Li L TI - [125I-labelled monoclonal antibody in the detection of leptospiral antigens in tissues of guinea pig] LA - Chi MH - Animal MH - Antibodies, Monoclonal/*diagnostic use MH - Antigens, Bacterial/*analysis MH - English Abstract MH - Guinea Pigs MH - Iodine Radioisotopes/diagnostic use MH - Leptospira interrogans/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Support, Non-U.S. Gov't MH - Tissue Distribution MH - Weil's Disease/immunology RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Iodine Radioisotopes) PT - JOURNAL ARTICLE DA - 860917 DP - 1985 Sep IS - 0253-4290 TA - Ssu Chuan I Hsueh Yuan Hsueh Pao PG - 185-7 CY - CHINA IP - 3 VI - 16 JC - VBT EM - 8611 PMID- 3837369 CU - 92 EA - A SO - Ssu Chuan I Hsueh Yuan Hsueh Pao 1985 Sep;16(3):185-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 86069408 AU - Hathaway SC AU - Marshall RB AU - Little TW AU - Headlam SA AU - Winter PJ TI - Identification by cross-agglutination absorption and restriction endonuclease analysis of leptospires of the Pomona serogroup isolated in the United Kingdom. LA - Eng MH - Agglutination Tests MH - Animal MH - DNA Restriction Enzymes MH - DNA, Bacterial/analysis MH - Great Britain MH - Leptospira/analysis/immunology/*isolation & purification RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 860108 DP - 1985 Sep IS - 0034-5288 TA - Res Vet Sci PG - 151-6 SB - M CY - ENGLAND IP - 2 VI - 39 JC - R7D AA - Author EM - 8603 AB - Five strains of Leptospira interrogans isolated in the United Kingdom and belonging to the Pomona serogroup were subjected to cross- agglutination absorption and bacterial restriction endonuclease DNA analysis (BRENDA) for their identification. British isolates were compared with reference strains representing the known serovars in the Pomona serogroup and also with isolates of the Pomona serogroup obtained from other countries. Three strains isolated from wildlife in England produced equivocal results when the cross-agglutination absorption and BRENDA results were compared. According to the World Health Organisation definition of a serovar the three English strains represented two new serovars, whereas by BRENDA all three had DNA electrophoresis patterns indistinguishable from serovar mozdok. Serovar pomona has not as yet been isolated in Great Britain and the epidemiology of the Pomona serogroup infections that have been detected by serology suggests that a serovar such as mozdok, maintained by wildlife, may be the causal agent. Two strains isolated in Northern Ireland were identified as pomona by the cross-agglutination absorption test. Further studies are needed to investigate the homogeneity of field and reference strains that are designated as pomona using the cross-agglutination absorption test. PMID- 2999928 CU - 93 SO - Res Vet Sci 1985 Sep;39(2):151-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 86069407 AU - Hathaway SC AU - Marshall RB AU - Little TW AU - Headlam SA AU - Winter PJ TI - Differentiation of reference strains of leptospires of the Pomona serogroup by cross-agglutination absorption and restriction endonuclease analysis. LA - Eng MH - Agglutination Tests MH - Animal MH - DNA Restriction Enzymes MH - DNA, Bacterial/*analysis MH - Leptospira/analysis/*classification/immunology MH - Rabbits RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 860108 DP - 1985 Sep IS - 0034-5288 TA - Res Vet Sci PG - 145-50 SB - M CY - ENGLAND IP - 2 VI - 39 JC - R7D AA - Author EM - 8603 AB - The serological classification of all reference strains that have been described as representing separate serovars of Leptospira interrogans within the Pomona serogroup was investigated using cross-agglutination absorption and bacterial restriction endonuclease analysis (BRENDA). Comparative cross-agglutination absorption studies indicated that cornelli CB, monjakov Monjakov and kennewicki LT1026 were homologous with pomona Pomona, and dania K1 and tsaratsova B81/7 were homologous with mozdok 5621. BRENDA confirmed these results, except that pomona Pomona and monjakov Monjakov showed a difference in the high molecular weight region. It is proposed that four serovars be currently recognised within the Pomona serogroup: pomona, mozdok, proechimys and tropica. The relative merits of the use of cross-agglutination absorption and BRENDA with respect to identification of Pomona serogroup isolates are discussed. PMID- 2999927 CU - 93 SO - Res Vet Sci 1985 Sep;39(2):145-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 86020540 AU - Ellis WA AU - O'Brien JJ AU - Bryson DG AU - Mackie DP TI - Bovine leptospirosis: some clinical features of serovar hardjo infection. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis/etiology MH - Female MH - Fetal Diseases/diagnosis/*veterinary MH - Leptospira interrogans/isolation & purification MH - Northern Ireland MH - Pregnancy MH - Seasons MH - Weil's Disease/diagnosis/*veterinary PT - JOURNAL ARTICLE DA - 851028 DP - 1985 Aug 3 IS - 0042-4900 TA - Vet Rec PG - 101-4 SB - M CY - ENGLAND IP - 5 VI - 117 JC - XBS AA - Author EM - 8601 AB - During an investigation of natural in utero infection of cattle by Leptospira interrogans strains, infection (almost entirely caused by serovar hardjo) was diagnosed in 57 per cent of 505 calves (472 aborted fetuses, 20 stillborn calves and 13 perinatal deaths) examined over a six-year period. The prevalence of leptospire-infected fetuses showed a seasonal increase in September, October and December and was significantly higher in fetuses aborted by dairy cows than in fetuses aborted by beef cows. The majority of infected fetuses were aborted from the sixth month of gestation onwards. Cows which aborted infected fetuses had not previously exhibited overt signs of agalactia. There was an association between leptospiral infection and retention of fetal membranes. PMID- 4049693 SO - Vet Rec 1985 Aug 3;117(5):101-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 86050230 AU - Elder JK AU - Pepper PM AU - Hill MW AU - Ward WH TI - The significance of leptospiral titres associated with bovine abortion. LA - Eng MH - Abortion, Veterinary/immunology/*microbiology MH - Animal MH - Antibodies, Bacterial/*immunology MH - Cattle MH - Cattle Diseases/immunology/*microbiology MH - Female MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Pregnancy RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 851220 DP - 1985 Aug IS - 0005-0423 TA - Aust Vet J PG - 258-62 SB - M CY - AUSTRALIA IP - 8 VI - 62 JC - 9IE AA - Author EM - 8602 AB - To investigate relationships between serological titres to 2 serovars, pomona (L. pomona) and hardjo (L. hardjo), of Leptospira interrogans and abortions, log linear and logit models were fitted to herd and individual cow data from cattle serologically negative for brucellosis. Serological titres to both serovars were significantly related to abortions in individual cows, with L. pomona having a stronger relationship than L. hardjo. L. hardjo was not significant when herd data were analysed. Differences between dairy and beef cattle in the serological titres found to both L. pomona and L. hardjo were detected when data sets of all cattle or cattle with no history of abortion were analysed. The beef/dairy differences may be due to different management practices and/or to different geographical distributions of both serovars and populations of beef and dairy cattle. If there are no cattle in a herd with a reciprocal titre of 3000 or greater for L. pomona, it is unlikely that L. pomona is associated with the abortion problem. There was no specific L. hardjo titre which separated high and low probabilities that the serum came from a cow or herd with an abortion history. PMID- 4062737 CU - 91 SO - Aust Vet J 1985 Aug;62(8):258-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 86020593 AU - Cousins DV AU - Robertson GM AU - Hustas L TI - The use of the enzyme-linked immunosorbent assay (ELISA) to detect the IgM and IgG antibody response to Leptospira interrogans serovars hardjo, pomona and tarassovi in cattle. LA - Eng MH - Agglutination Tests MH - Animal MH - Bacteriuria/veterinary MH - Cattle MH - Cattle Diseases/*diagnosis/immunology MH - Cross Reactions MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - IgG/*analysis MH - IgM/*analysis MH - Leptospira interrogans/classification/*immunology MH - Leptospirosis/diagnosis/immunology/*veterinary MH - Male MH - Serotyping MH - Support, Non-U.S. Gov't MH - Time Factors PT - JOURNAL ARTICLE DA - 851118 DP - 1985 Aug IS - 0378-1135 TA - Vet Microbiol PG - 439-50 SB - M CY - NETHERLANDS IP - 5 VI - 10 JC - XBW AA - Author EM - 8601 AB - Leptospira interrogans serovars pomona, hardjo and tarassovi were each used to inoculate 6 cattle. Three-hundred and ninety-nine sera collected from the inoculated animals and from a control group over a 3- month period were tested using the microscopic agglutination test (MAT) and the enzyme-linked immunosorbent assay (ELISA). Leptospiruria was monitored by microscopic examination and culture. The ELISA detected specific IgM antibody against the serovars in all infected cattle 1 week after inoculation. This IgM antibody persisted in most of the animals for 3-5 weeks. Specific IgG antibody appeared at the same time or just after IgM, but persisted for much longer. Levels of antibody detected by the ELISA and the MAT did not correlate with each other, nor with the periods of leptospiruria found in the infected cattle. PMID- 4049731 CU - 90 SO - Vet Microbiol 1985 Aug;10(5):439-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 85277614 AU - Mapp C AU - Hartiala J AU - Frick OL AU - Shields RL AU - Gold WM TI - Airway responsiveness to inhaled antigen, histamine, and methacholine in inbred, ragweed-sensitized dogs. LA - Eng MH - Animal MH - Asthma/immunology/*physiopathology MH - Bronchial Provocation Tests/*methods MH - Disease Models, Animal MH - Dogs MH - Female MH - Histamine/diagnostic use MH - IgE/analysis MH - Immunization MH - Male MH - Methacholine Compounds/diagnostic use MH - Pollen/immunology MH - Radioallergosorbent Test MH - Skin Tests MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. RN - 0 (Methacholine Compounds) RN - 37341-29-0 (IgE) RN - 51-45-6 (Histamine) RN - 55-92-5 (Methacholine Chloride) PT - JOURNAL ARTICLE ID - HL-24136/HL/NHLBI ID - R01-AI-15233/AI/NIAID ID - ES-01684-21/ES/NIEHS DA - 850912 DP - 1985 Aug IS - 0003-0805 TA - Am Rev Respir Dis PG - 292-8 SB - A SB - M CY - UNITED STATES IP - 2 VI - 132 JC - 426 AA - Author EM - 8511 AB - We studied the responses to antigen in animals selected from a colony of inbred dogs sensitized to specific allergens to determine if they had characteristics similar to those of human asthmatics. They were immunized with ragweed and grass pollen extracts (10 micrograms in alum) immediately after routine vaccination with attenuated live virus (distemper and hepatitis) and killed bacteria (Leptospira) at 4, 8, and 12 wk of age. Subsequently, ragweed and grass injections were repeated every 2 months. Immunized dogs made specific IgE-antibodies in serum averaging 3 to 4 times that of control animals (no immunization with pollen or vaccine). They showed positive skin responses to the injection of ragweed pollen extract, whereas control dogs did not respond to ragweed pollen by quantitative skin test or inhalation challenge. In immunized dogs under barbiturate anesthesia, air-flow resistance of the total respiratory system increased from 0.60 +/- 0.07 (mean +/- SEM) before to 12.6 +/- 3.4 cm H2O/lps 5 min after the start of antigen aerosol; respiratory resistance remained increased for 20 min and was associated with 0 hypoxemia and increased arterial plasma histamine. In addition, airway responsiveness to both inhaled histamine and methacholine was greater in immunized dogs than in nonimmunized dogs of comparable age. Airway responses to each agonist were highly reproducible on repeated testing. These results indicate that physiologic responses to antigen by inbred, ragweed-sensitized dogs resemble human asthma closely and that these dogs appear suitable for a variety of experimental studies of asthma with respect to pathogenesis, diagnosis, prevention, and treatment. PMID- 3896078 CU - 96 SO - Am Rev Respir Dis 1985 Aug;132(2):292-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 86020528 AU - Ellis WA AU - McParland PJ AU - Bryson DG AU - McNulty MS TI - Leptospires in pig urogenital tracts and fetuses. LA - Eng MH - *Abortion, Veterinary MH - Animal MH - Female MH - Fetus/*microbiology MH - Leptospira/*isolation & purification MH - Male MH - Placenta/microbiology MH - Pregnancy MH - Swine/*microbiology MH - Urogenital System/*microbiology PT - JOURNAL ARTICLE DA - 851028 DP - 1985 Jul 20 IS - 0042-4900 TA - Vet Rec PG - 66-7 SB - M CY - ENGLAND IP - 3 VI - 117 JC - XBS EM - 8601 PMID- 4049685 SO - Vet Rec 1985 Jul 20;117(3):66-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 86021515 AU - Sakamoto N AU - Yanagawa R AU - Ono E AU - Kida H AU - Mori M AU - Arimitsu Y AU - Akama K AU - Yasuda J AU - Too K TI - Detection of antibodies to leptospiral genus-specific antigen in human and animal sera by indirect hemagglutination test with a partially purified genus-specific protein antigen. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antibody Specificity MH - Antigens, Bacterial/*immunology MH - Bacterial Proteins/*immunology MH - Cattle MH - Cattle Diseases/immunology MH - Dog Diseases/immunology MH - Dogs MH - *Hemagglutination Tests/veterinary MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*immunology/veterinary MH - Swine MH - Swine Diseases/immunology MH - Weil's Disease/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE DA - 851112 DP - 1985 Jul IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 548-56 SB - M CY - GERMANY, WEST IP - 4 VI - 259 JC - Y55 AA - Author EM - 8601 AB - Antibodies against leptospiral genus-specific antigen were detected in the sera from clinically diagnosed human leptospirosis and suspected animal leptospirosis by indirect hemagglutination (IHA) test with a partially purified genus-specific protein antigen (GP-Ag). The reaction was positive in the infected humans and animals irrespective of the leptospiral serovars. No significant correlation was found between IHA titer against GP-Ag and microscopic agglutination (MA) titer. IHA titer did not always develop in parallel with MA titers. Sera obtained from healthy individuals were negative in both IHA and MA tests. PMID- 4050200 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1985 Jul;259(4):548-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 85277428 AU - Ram P AU - Chandra MS TI - Unusual electrocardiographic abnormality in leptospirosis: case reports. LA - Eng MH - Adult MH - Aged MH - Case Report MH - *Electrocardiography MH - Fiji MH - Fluid Therapy MH - Human MH - Leptospirosis/blood/*physiopathology/therapy MH - Male MH - Middle Age MH - Myocarditis/physiopathology MH - Penicillin G/therapeutic use MH - Peritoneal Dialysis MH - Weil's Disease/physiopathology RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 850903 DP - 1985 Jul IS - 0003-3197 TA - Angiology PG - 477-82 SB - M CY - UNITED STATES IP - 7 VI - 36 JC - 4UA AA - Author EM - 8511 AB - Unusual ECG changes of marked ST segment elevation in leads V1 to V3 are reported in four cases of severe icteric leptospirosis for the first time. These changes normalized rapidly with initiation of therapy and recovery in three patients. One patient died within hours of admission. The causes for the changes are not clear. PMID- 4025952 SO - Angiology 1985 Jul;36(7):477-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 85266941 AU - Barsic B AU - Macek P AU - Petricevic I AU - Kosutic Z TI - [Rare clinical manifestations of leptospirosis] LA - Scr MH - Adolescence MH - Adult MH - Child MH - Electrocardiography MH - English Abstract MH - Female MH - Human MH - Male MH - Middle Age MH - Weil's Disease/*diagnosis/physiopathology PT - JOURNAL ARTICLE DA - 850916 DP - 1985 Jul IS - 0024-3477 TA - Lijec Vjesn PG - 286-9 CY - YUGOSLAVIA IP - 7 VI - 107 JC - L6C EM - 8511 PMID- 4021714 TT - Rjede klinicke znacajke u leptospiroza. EA - A SO - Lijec Vjesn 1985 Jul;107(7):286-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 86037771 AU - Chen T TI - [Development and present status of a leptospiral vaccine and the technology of vaccine production in China] LA - Jpn MH - Animal MH - China MH - Clinical Trials MH - Disease Outbreaks MH - Human MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*prevention & control MH - Quality Control MH - Technology, Pharmaceutical MH - *Vaccines/standards RN - 0 (Vaccines) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE DA - 851216 DP - 1985 Jul IS - 0021-4930 TA - Nippon Saikingaku Zasshi PG - 755-62 CY - JAPAN IP - 4 VI - 40 JC - KHZ EM - 8602 PMID- 3903244 CU - 91 SO - Nippon Saikingaku Zasshi 1985 Jul;40(4):755-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 86021561 AU - Dain AA AU - Rozinov MN AU - Gol'tsmaier TA AU - Gershanovich VN AU - Chernukha IuG TI - [Cloning and the expression of the hemolysin gene of Leptospira pomona pomona in Escherichia coli] LA - Rus MH - Cloning, Molecular/*methods MH - DNA, Bacterial/genetics MH - English Abstract MH - Escherichia coli/*genetics MH - *Gene Expression Regulation MH - *Genes, Bacterial MH - Hemolysins/*genetics MH - Leptospira/*genetics MH - Transformation, Bacterial RN - 0 (DNA, Bacterial) RN - 0 (Hemolysins) PT - JOURNAL ARTICLE DA - 851113 DP - 1985 Jul IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 7-10 SB - M CY - USSR IP - 7 JC - Y9O AA - Author EM - 8601 AB - The library of Leptospira pomona genes was obtained on phage vector AL 47.1. From this library a recombinant phage carrying the hemolysin gene was selected. The DNA fragment (7.7 kb) of this phage containing the hemolysin gene was subcloned on plasmid pUC19. E. coli clones with hybrid plasmid pDR7 were shown to be hemolytic, but the secretion of hemolysin by E. coli into the culture medium was not observed. PMID- 3901626 CU - 91 TT - Klonirovanie i ekspressiia gena gemolizina Leptospira pomona pomona v Escherichia coli. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1985 Jul;(7):7-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 86021510 AU - Terpstra WJ AU - Korver H AU - van Leeuwen J AU - Klatser PR AU - Kolk AH TI - The classification of Sejroe group serovars of Leptospira interrogans with monoclonal antibodies. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Monoclonal/biosynthesis/*diagnostic use MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Hybridomas/immunology MH - Immunoenzyme Techniques MH - Leptospira interrogans/*classification MH - Mice MH - Serotyping/methods RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 851112 DP - 1985 Jul IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 498-506 SB - M CY - GERMANY, WEST IP - 4 VI - 259 JC - Y55 AA - Author EM - 8601 AB - Using the hybridoma technique we produced monoclonal antibodies to serovars of Leptospira interrogans. We focussed on serovar hardjo which is an important pathogen for humans and animals, and on other serovars of the Sejroe group. With combinations of monoclonals, characteristic patterns of agglutination were observed according to the specific pattern of antigenic determinants of that serovar. A set of 13 monoclonal antibodies was composed which allowed the classification of almost all serovars of the Sejroe group. PMID- 3901617 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1985 Jul;259(4):498-506 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 86021516 AU - Sakamoto N AU - Ono E AU - Kida H AU - Yanagawa R TI - Production of monoclonal antibodies against leptospiral genus-specific protein antigen and localization of the antigen by immunoelectron microscopy. LA - Eng MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Antibodies, Monoclonal/*biosynthesis MH - Antigens, Bacterial/*immunology/isolation & purification MH - Bacterial Proteins/*immunology MH - Cell Wall/immunology MH - Epitopes MH - Hybridomas MH - Immunoenzyme Techniques MH - Leptospira interrogans/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Microscopy, Electron RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 851112 DP - 1985 Jul IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 557-63 SB - M CY - GERMANY, WEST IP - 4 VI - 259 JC - Y55 AA - Author EM - 8601 AB - Monoclonal antibodies were first produced against a leptospiral genus- specific protein antigen (GP-Ag) isolated from Leptospira interrogans serovar kremastos strain Kyoto. The representative monoclonal antibody (GP-7) did not agglutinate kremastos Kyoto but reacted with Triton X- 100 treated kreamastos Kyoto, andamana, patoc and Urawa in enzyme- linked immunosorbent assay (ELISA), indicating that the monoclonal antibody recognized the genus-specific determinant of GP-Ag. The localization of GP-Ag was investigated by immunoelectron microscopy with the iodinated antibody and peroxidase-labeled antibody. The genus- specific determinant of GP-Ag recognized by GP-7 was located on the subsurface of the leptospiral envelope. PMID- 2413657 CU - 95 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1985 Jul;259(4):557-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 86021511 AU - Sakamoto N AU - Ono E AU - Kida H AU - Yanagawa R TI - Characterization of a partially purified leptospiral genus-specific protein antigen. LA - Eng MH - Agglutination Tests MH - Antibodies, Monoclonal MH - Antigens, Bacterial/*analysis/isolation & purification MH - Bacterial Proteins/analysis/*immunology MH - Complement Fixation Tests MH - Electrophoresis, Polyacrylamide Gel MH - Enzyme-Linked Immunosorbent Assay MH - Epitopes MH - Heat MH - Immunodiffusion MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Periodic Acid/pharmacology MH - Precipitation RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Proteins) RN - 0 (Epitopes) RN - 10450-60-9 (Periodic Acid) RN - 7790-28-5 (metaperiodate) PT - JOURNAL ARTICLE DA - 851112 DP - 1985 Jul IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 507-19 SB - M CY - GERMANY, WEST IP - 4 VI - 259 JC - Y55 AA - Author EM - 8601 AB - A leptospiral genus-specific protein antigen (GP-Ag) was partially purified from Leptospira interrogans serovar kremastos strain Kyoto and canicola strain Hond Utrecht IV, by treating the organisms with Triton X-100 followed by a purification procedure including fractionation with DEAE-cellulose column chromatography and ethanol precipitation. Genus- specificity of the antigens from kremastos Kyoto and canicola was shown by the immunodiffusion (ID) test. Complement fixation (CF) test and enzyme-linked immunosorbent assay (ELISA) using GP-Ag from kremastos Kyoto showed the genus specificity of the GP-Ag. Sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) of the antigens from kremastos Kyoto and canicola showed a major band with Coomassie blue stain. The band of GP-Ag from kremastos Kyoto was also shown by immunoprecipitation using the monoclonal antibody (GP-7) to GP-Ag from kremastos Kyoto. The molecular weight of the genus-specific antigen was estimated to be approximately 62 000. The genus specificity of the antigen was reduced by heating at 100 degrees C or treatment with proteolytic enzymes, but not reduced by treatment with sodium metaperiodate. PMID- 2413655 CU - 95 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1985 Jul;259(4):507-19 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 85277549 AU - Fairbrother JM TI - Antibody response to genus- and serovar-specific leptospiral antigens in Leptospira-infected cows. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Antigens, Bacterial/*immunology MH - Cattle MH - Cattle Diseases/*immunology MH - Enzyme-Linked Immunosorbent Assay MH - Epitopes MH - Female MH - Leptospira interrogans/classification/*immunology MH - Mercaptoethanol/pharmacology MH - Serotyping MH - Weil's Disease/immunology/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) RN - 60-24-2 (Mercaptoethanol) PT - JOURNAL ARTICLE DA - 850911 DP - 1985 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1422-6 SB - M CY - UNITED STATES IP - 7 VI - 46 JC - 40C AA - Author EM - 8511 AB - In cows inoculated with Leptospira interrogans serovar pomona or hardjo, the 2-mercaptoethanol-sensitive microscopic agglutination test (MAT) antibody to the serovar appeared 3 to 8 days after inoculation and peaked at 10 to 20 days, whereas the 2-mercaptoethanol-resistant MAT antibody was predominant at 35 to 80 days. A persistent antibody response, probably associated with serovar-specific leptospiral antigens, was detected in the cows inoculated with serovar pomona, using a sonicated or an alkaline-extracted antigen derived from serovar pomona in the enzyme-linked immunosorbent assay (ELISA). In contrast, a short-lived antibody response to the same antigens was demonstrated in cows inoculated with serovar hardjo, probably more typical of the response to genus-specific leptospiral antigens. Antigens derived from L biflexa serovar patoc only detected the latter type of antibody response in cows inoculated with serovar pomona or hardjo. Correlative studies revealed that the antigens derived from serovar patoc seem to be genus specific and serologically closely related, but not identical. The antigens derived from serovar pomona were genus specific on the basis of the early antibody response to leptospiral inoculation in the cows, but serovar specific based on the subsequent more persistent response to leptospiral inoculation. These antigens were also serologically closely related, but not identical. Examination of sera from cows that aborted and were MAT-positive for serovar pomona or hardjo revealed a more serovar-specific antibody response, indicating that there may have been a less recent leptospiral antigenic stimulus, thus emphasizing the caution with which results of the ELISA and other serologic assays for the detection of bovine leptospirosis must be interpreted. PMID- 2411175 CU - 95 SO - Am J Vet Res 1985 Jul;46(7):1422-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 85227288 AU - Gill N AU - Waitkins SA AU - Calder IM TI - Further update on leptospirosis: continuing risk in fish farmers [letter] LA - Eng MH - Adolescence MH - Adult MH - *Fisheries MH - Human MH - Male MH - Middle Age MH - Occupational Diseases/*epidemiology MH - Risk MH - Weil's Disease/*epidemiology PT - LETTER DA - 850820 DP - 1985 Jun 29 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 1988 SB - A SB - M SB - X CY - ENGLAND IP - 6486 VI - 290 JC - B4X EM - 8510 PMID- 3924335 CU - 91 SO - Br Med J (Clin Res Ed) 1985 Jun 29;290(6486):1988 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 85241196 TI - Zoonoses. LA - Eng MH - Animal MH - Brucellosis/*prevention & control MH - Human MH - Leptospirosis/*prevention & control MH - New Zealand MH - Toxoplasmosis/*prevention & control MH - Zoonoses/*prevention & control PT - JOURNAL ARTICLE DA - 850812 DP - 1985 Jun 26 IS - 0028-8446 TA - N Z Med J PG - 503-4 SB - M CY - NEW ZEALAND IP - 781 VI - 98 JC - OBQ EM - 8510 PMID- 3859777 CU - 88 NI - A SO - N Z Med J 1985 Jun 26;98(781):503-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 86084796 AU - Larsson CE AU - Santa Rosa CA AU - Larsson MH AU - Birgel EH AU - Fernandes WR AU - Paim GV TI - Laboratory and clinical features of experimental feline leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacteriuria/microbiology/veterinary MH - Cat Diseases/immunology/*microbiology MH - Cats MH - Female MH - Leptospira canicola/immunology/*isolation & purification MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - Male MH - Septicemia/microbiology/veterinary MH - Weil's Disease/immunology/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860218 DP - 1985 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 111-9 SB - M CY - TAIWAN IP - 2 VI - 12 JC - GTK AA - Author EM - 8604 AB - In order to assess the clinical, laboratorial and epidemiological aspects of feline leptospirosis, ten female and male adult cats were experimentally inoculated with pathogenic and autochthonous field isolate of Leptospira interrogans. Five of them were inoculated subcutaneously with serovar icterohaemorrhagiae (R-192) and the others five with serovar canicola. No clinical and laboratorial alterations were found in these animals. Antileptospiral agglutinins were detected in 90% of the infected cats, shortly after the 1st week after inoculation. The leptospiral agglutinins were detected for 8 to 12 weeks and the elimination of leptospires through urine was observed only in animals infected with serovar canicola, beginning 2 to 4 weeks after inoculation and lasting for 2 to 8 weeks. Isolations of leptospires from blood and kidneys were unsuccessful. PMID- 4077410 CU - 91 SO - Int J Zoonoses 1985 Jun;12(2):111-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 86070475 AU - Elwell MR AU - Ward GS AU - Hansukjariya P AU - Tingpalapong M TI - Doxycycline prophylaxis for experimental leptospira infection in non- human primates and hamsters. LA - Eng MH - Animal MH - Doxycycline/pharmacology/*therapeutic use MH - Hamsters MH - In Vitro MH - Leptospira interrogans/drug effects/isolation & purification MH - Macaca mulatta MH - Time Factors MH - Weil's Disease/*prevention & control RN - 564-25-0 (Doxycycline) PT - JOURNAL ARTICLE DA - 860114 DP - 1985 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 268-73 SB - M CY - THAILAND IP - 2 VI - 16 JC - UVN AA - Author EM - 8603 AB - Doxycycline was effective as a chemoprophylactic agent for experimental Leptospira infection in non-human primates and hamsters. Monkeys injected intraperitoneally with Leptospira bataviae, and receiving only diluent as treatment developed a leptospiremia during the first week and later leptospires were cultured from the cerebrospinal fluid and urine. Monkeys treated daily with oral doxycycline for 10 days beginning one day before infection had a shortened period of detectable leptospiremia, and organisms were never detected in the cerebrospinal fluid or urine. Even an oral dose of doxycycline 2 hours before infection and on day 7 prevented the later infection of the cerebrospinal fluid and urine. In hamsters, doxycycline treatment prevented deaths from acute Leptospira infection and when hamsters were treated daily for 4 or more days, renal infection was prevented. The results of animal studies, the susceptibility of LC0475 and the five other isolates to doxycycline in vitro, and lack of evidence for antibiotic resistance in culture suggests this antibiotic may be useful as a prophylactic drug for high risk groups and an effective treatment for leptospirosis in Thailand. PMID- 4071199 CU - 90 SO - Southeast Asian J Trop Med Public Health 1985 Jun;16(2):268-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85246128 AU - Stevens AE AU - Headlam SA AU - Pritchard DG AU - Thorns CJ AU - Morris JA TI - Monoclonal antibodies for diagnosis of infection with Leptospira interrogans serovar hardjo by immunofluorescence. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Monoclonal/*diagnostic use MH - Cattle MH - Cattle Diseases/*diagnosis MH - *Fluorescent Antibody Technique MH - Hybridomas/immunology MH - Leptospira interrogans/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Serotyping MH - Weil's Disease/diagnosis/*veterinary RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 850820 DP - 1985 Jun 1 IS - 0042-4900 TA - Vet Rec PG - 593-4 SB - M CY - ENGLAND IP - 22 VI - 116 JC - XBS EM - 8510 PMID- 3892877 CU - 91 SO - Vet Rec 1985 Jun 1;116(22):593-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 86291333 AU - Zhang FZ AU - Wang JJ AU - Meng PY AU - Long PR AU - Hu MZ TI - [Three new serovars in Leptospira interrogans] LA - Chi MH - Agglutination Tests MH - China MH - English Abstract MH - Leptospira interrogans/*classification MH - Nomenclature MH - Serotyping PT - JOURNAL ARTICLE DA - 860917 DP - 1985 Jun IS - 0001-6209 TA - Wei Sheng Wu Hsueh Pao PG - 102-7 CY - CHINA IP - 2 VI - 25 JC - XNA EM - 8611 PMID- 3837543 EA - A SO - Wei Sheng Wu Hsueh Pao 1985 Jun;25(2):102-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 85200717 AU - Waitkins SA TI - From the PHLS. Update on leptospirosis. LA - Eng MH - Animal MH - Cattle MH - Dairying MH - Great Britain MH - Human MH - Leptospirosis/epidemiology/*transmission MH - Male MH - Occupational Diseases MH - Water RN - 7732-18-5 (Water) PT - JOURNAL ARTICLE DA - 850722 DP - 1985 May 18 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 1502-3 SB - A SB - M SB - X CY - ENGLAND IP - 6480 VI - 290 JC - B4X EM - 8509 PMID- 3922549 CU - 91 SO - Br Med J (Clin Res Ed) 1985 May 18;290(6480):1502-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 85287599 AU - Galli M AU - Esposito R AU - Crocchiolo P AU - Chemotti M AU - Gasparro M AU - Dall'Aglio PP TI - Immune complexes in leptospirosis [letter] LA - Eng MH - Antigen-Antibody Complex/*analysis MH - Human MH - Lyme Disease/immunology MH - Weil's Disease/*immunology RN - 0 (Antigen-Antibody Complex) PT - LETTER DA - 851023 DP - 1985 May-Jun IS - 0300-8126 TA - Infection PG - 156 SB - M CY - GERMANY, WEST IP - 3 VI - 13 JC - GO8 EM - 8512 PMID- 4030109 CU - 92 SO - Infection 1985 May-Jun;13(3):156 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 85246657 AU - Falk VS TI - Leptospirosis in Wisconsin: report of a case associated with direct contact with raccoon urine. LA - Eng MH - Adult MH - Animal MH - Case Report MH - Human MH - Leptospirosis/*transmission MH - Male MH - *Raccoons MH - Urine/*microbiology MH - Wisconsin MH - Zoonoses/*transmission PT - JOURNAL ARTICLE DA - 850812 DP - 1985 May IS - 0043-6542 TA - Wis Med J PG - 14-5 CY - UNITED STATES IP - 5 VI - 84 JC - XPJ EM - 8510 PMID- 4013366 SO - Wis Med J 1985 May;84(5):14-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 85207182 AU - Magnarelli LA AU - Anderson JF AU - Kaufmann AF AU - Lieberman LL AU - Whitney GD TI - Borreliosis in dogs from southern Connecticut. LA - Eng MH - Animal MH - Animals, Wild MH - Antibodies, Bacterial/analysis MH - Borrelia/immunology/isolation & purification MH - Borrelia Infections/epidemiology/immunology/*veterinary MH - Connecticut MH - Disease Reservoirs/veterinary MH - Dog Diseases/*epidemiology/immunology/microbiology MH - Dogs MH - Female MH - Leptospira/immunology/isolation & purification MH - Lyme Disease/epidemiology/immunology/veterinary MH - Male MH - Ticks/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850712 DP - 1985 May 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 955-9 SB - M CY - UNITED STATES IP - 9 VI - 186 JC - HAV AA - Author EM - 8509 AB - Blood samples were obtained from dogs in tick-infested regions of southern Connecticut to assess canine exposure to Borrelia burgdorferi, the etiologic agent of Lyme disease in human beings. An indirect fluorescent antibody test detected immunoglobulin (Ig)M antibodies at titers of 1:64 to 1:512 in 22 of 84 serum samples previously shown to be positive with a polyvalent rabbit anti-dog total Ig conjugate. Analyses of paired serum samples from 20 seropositive dogs revealed temporal differences in titers; changes occurred during brief (1 month) or extended (greater than 4 years) sampling periods. Clinical records for 52 seropositive dogs indicated a history of intermittent lameness in 19 of these. Limb/joint disorders typically developed in dogs without IgM antibodies, suggesting manifestation during later phases of illness. A microscopic-agglutination test was used to assess cross reactivity between B burgdorferi and 20 serovars of Leptospira interrogans and biflexa. Analyses of 63 dog serum specimens with antibodies to B burgdorferi and a series of reference rabbit sera revealed minor antigenic relatedness. There was geographic clustering of dogs with antibodies to B burgdorferi in areas of south-central and southeastern Connecticut, where human Lyme disease also occurs. PMID- 3997647 CU - 91 SO - J Am Vet Med Assoc 1985 May 1;186(9):955-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 85181644 AU - Nunes-Edwards PL AU - Thiermann AB AU - Bassford PJ Jr AU - Stamm LV TI - Identification and characterization of the protein antigens of Leptospira interrogans serovar hardjo. LA - Eng MH - Antigens, Bacterial/*analysis/immunology MH - Bacterial Outer Membrane Proteins/analysis/*immunology MH - Cross Reactions MH - Electrophoresis, Polyacrylamide Gel MH - Leptospira interrogans/classification/*immunology/pathogenicity MH - Precipitin Tests MH - Serotyping MH - Species Specificity MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) PT - JOURNAL ARTICLE DA - 850610 DP - 1985 May IS - 0019-9567 TA - Infect Immun PG - 492-7 SB - M SB - X CY - UNITED STATES IP - 2 VI - 48 JC - GO7 AA - Author EM - 8508 AB - We radiolabeled Leptospira proteins with [35S]methionine. Solubilized extracts of radiolabeled L. interrogans serovar hardjo strain hardjoprajitno were analyzed by one-dimensional sodium dodecyl sulfate- polyacrylamide gel electrophoresis and fluorography. We compared the protein profile obtained in this manner to the protein profiles of various [35S]methionine-labeled Leptospira spp. The profiles of the pathogenic L. interrogans strains were very similar but not identical and exhibited no obvious relationship to those of the two nonpathogenic species. We used solubilized, radiolabeled hardjoprajitno extracts and a sensitive radioimmunoprecipitation procedure to identify protein antigens recognized by immunoglobulin G antibodies present in various rabbit anti-hardjo sera. Homologous hyperimmune rabbit serum efficiently precipitated a large subset of proteins, the majority of which were between 30,000 and 66,500 daltons. Radioimmunoprecipitations with sera prepared against each of four recent hardjo isolates cultured from infected cattle produced similar results. Immunoprecipitations done with various radiolabeled Leptospira extracts and anti- hardjoprajitno serum demonstrated that the pathogenic leptospires possessed a number of cross-reactive major and minor protein antigens. By cell fractionation procedures, we found that most of the major protein antigens were present in the outer envelope. These proteins were exposed on the leptospiral cell surface because intact radiolabeled leptospires bound antibodies directed against them. PMID- 3988343 CU - 91 SO - Infect Immun 1985 May;48(2):492-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 85241729 AU - Daiter AB TI - [Natural-focus infections in urbanized landscapes] LA - Rus MH - Animal MH - *Disease Reservoirs MH - Encephalitis, Tick-Borne/etiology MH - English Abstract MH - *Health MH - Hemorrhagic Fever with Renal Syndrome/etiology MH - Human MH - Leptospirosis/etiology MH - Mice MH - Rats MH - Rodent Diseases/transmission MH - Russia MH - *Urban Health MH - Yersinia pseudotuberculosis Infections/etiology MH - Zoonoses/etiology PT - JOURNAL ARTICLE DA - 850816 DP - 1985 May-Jun IS - 0031-1847 TA - Parazitologiia PG - 169-76 SB - M CY - USSR IP - 3 VI - 19 JC - ORB AA - Author EM - 8510 AB - The data on natural-nidal diseases typical for cities, urban agglomerations and culture coenoses are summarized in the paper in the light of academician E. N. Pavlovsky's theory. According to the ecological principle all infections with natural nidality are classified into two large groups. Concrete data from the north-western region show the role of leptospirosis, haemorrhagic fever with renal syndrome, tick--borne encephalitis and pseudotuberculosis in urbanized landscapes. Modern epidemiological tendences of these diseases, associated with functioning of their natural and economic nidi, are stressed. PMID- 2861593 CU - 94 TT - Prirodno-ochagovye infektsii v urbanizirovannykh landshaftakh. EA - A SO - Parazitologiia 1985 May-Jun;19(3):169-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 85214968 TI - [Leptospirosis with fatal outcome (letter)] LA - Hun MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Human MH - Hungary MH - Male MH - United States MH - Weil's Disease/diagnosis/epidemiology/*pathology PT - LETTER DA - 850627 DP - 1985 Apr 21 IS - 0030-6002 TA - Orv Hetil PG - 1001 CY - HUNGARY IP - 16 VI - 126 JC - OL8 EM - 8509 PMID- 4000662 CU - 91 NI - A TT - Adatok a letalis kimenetelu leptospirosishoz. SO - Orv Hetil 1985 Apr 21;126(16):1001 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 85294186 AU - Asauliuk IK AU - Stanislavskii OK AU - Bubnov AN TI - [Hemosorption in the combined treatment of leptospirosis patients in the liver-kidney failure stage] LA - Rus MH - Combined Modality Therapy MH - Hemodialysis MH - *Hemoperfusion/methods MH - Human MH - Kidney Failure, Acute/etiology/*therapy MH - Liver Diseases/etiology/*therapy MH - Weil's Disease/complications/*therapy PT - JOURNAL ARTICLE DA - 850930 DP - 1985 Apr IS - 0023-2149 TA - Klin Med (Mosk) PG - 114-7 CY - USSR IP - 4 VI - 63 JC - KW2 EM - 8512 PMID- 4032992 TT - Gemosorbtsiia v kompleksnom lechenii bol'nykh leptospirozom v stadii pechenochno-pochechnoi nedostatochnosti. SO - Klin Med (Mosk) 1985 Apr;63(4):114-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 85254821 AU - Yang WY TI - [Morbidity of leptospirosis in Meng-lian County in Yunnan Province] LA - Chi MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - China MH - Diagnostic Errors MH - English Abstract MH - Female MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 850823 DP - 1985 Apr IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 78-81 CY - CHINA IP - 2 VI - 6 JC - CQG EM - 8511 PMID- 4016899 CU - 88 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1985 Apr;6(2):78-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 85247127 AU - Vasiurenko ZP AU - Bernasovskaia EP AU - Kondratenko VN TI - [Fatty acid composition of Leptospira lipids as a taxonomic criterion] LA - Rus MH - Chromatography, Thin Layer MH - Comparative Study MH - English Abstract MH - Fatty Acids/*analysis MH - Leptospira/*analysis/classification/pathogenicity MH - Leptospira interrogans/analysis/classification/pathogenicity MH - Lipids/*analysis MH - Phospholipids/analysis RN - 0 (Fatty Acids) RN - 0 (Phospholipids) PT - JOURNAL ARTICLE DA - 850814 DP - 1985 Apr IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 6-11 SB - M CY - USSR IP - 4 JC - Y9O AA - Author EM - 8510 AB - The fatty-acid composition of microbial cells in 17 pathogenic and saprophytic Leptospira strains, comprising 14 serovars and 10 serogroups, has been studied. The strains under investigation have proved to fall into 3 groups differing by this characteristic. The group of saprophytic strains is characterized by a comparatively high level of myristic acid and, consequently, by the ratio of saturated and unsaturated fatty acids with 14 carbon atoms approaching 1:1; besides, it is also characterized by a lower, in comparison with the pathogenic Leptospira strains belonging to the serogroups Icterohaemorrhagiae, Canicola, Ballum has a higher level of unsaturated fatty acids. The second group of pathogenic Leptospira strains including the serogroups Grippotyphosa, Hebdomadis, Pomona, Tarassovi, Pyrogenes, Australia has been found to occupy an intermediate position between the first group of pathogenic Leptospira strains and the group of saprophytic ones. As the difference in the content of myristic acid in pathogenic and saprophytic Leptospira strains is a stable characteristic, it can be used for the differentiation of these strains. The present investigation has revealed that the distribution of the main fatty acids in Leptospira phospholipids is similar to their distribution in Leptospira neutral lipids with the exception of unsaturated fatty acid with 14 carbon atoms, occurring mainly in phospholipids. PMID- 4013576 CU - 92 TT - Zhirnokislotnyi sostav lipidov leptospir kak taksonomicheskii kriterii. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1985 Apr;(4):6-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [211 medline neighbors] UI - 85211144 AU - Davidson WR AU - Crum JM AU - Blue JL AU - Sharp DW AU - Phillips JH TI - Parasites, diseases, and health status of sympatric populations of fallow deer and white-tailed deer in Kentucky. LA - Eng MH - Animal MH - Bacterial Infections/diagnosis/*veterinary MH - *Deer/immunology/parasitology MH - Female MH - Health Status MH - Kentucky MH - Male MH - Mycoses/diagnosis/*veterinary MH - Parasitic Diseases/diagnosis/*veterinary MH - Species Specificity MH - Support, U.S. Gov't, Non-P.H.S. MH - Virus Diseases/diagnosis/*veterinary PT - JOURNAL ARTICLE DA - 850722 DP - 1985 Apr IS - 0090-3558 TA - J Wildl Dis PG - 153-9 SB - M CY - UNITED STATES IP - 2 VI - 21 JC - KEM AA - Author EM - 8509 AB - In August 1983, a study on parasites, diseases, and health status was conducted on sympatric populations of fallow deer (Dama dama) and white- tailed deer (Odocoileus virginianus) from Land Between The Lakes, Lyon and Trigg counties, Kentucky. Five adult deer of each species were studied. White-tailed deer had antibodies to epizootic hemorrhagic disease (EHD) virus and Leptospira interogans serovariety icterohemorrhagiae, and fallow deer had antibodies to bluetongue and EHD viruses. Serologic tests for bovine virus diarrhea virus, infectious bovine rhinotracheitis virus, parainfluenza3 virus, and Brucella spp. were negative. One white-tailed deer had an infectious cutaneous fibroma, and one fallow deer had pulmonary mucormycosis. White-tailed deer harbored 16 species of parasites, all of which are considered typical of the parasite fauna of this host in the southeastern United States. Fallow deer harbored nine species of parasites, including eight species known to occur in white-tailed deer on the area and one species (Spiculopteragia assymmetrica) that is not. All fallow deer had inflammatory lesions in the spinal cord and/or brain that were attributed to prior infection with meningeal worm (Parelaphostrongylus tenuis), indicating that P. tenuis infections are not always fatal for this species. The apparent high rate of exposure of Land Between The Lakes fallow deer to P. tenuis without a resultant high rate of clinical cerebrospinal parelaphostrongylosis is hypothesized to be due to a low prevalence and intensity of P. tenuis, partial innate resistance of fallow deer, and acquired immunity. PMID- 3999248 CU - 90 SO - J Wildl Dis 1985 Apr;21(2):153-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 85254107 AU - Ainsworth AJ AU - Lester TL AU - Capley G TI - Monoclonal antibodies to Leptospira interrogans serovar pomona. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis/*immunology MH - Antibodies, Monoclonal/biosynthesis/*immunology MH - Antibody Specificity MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique MH - Hybridomas/metabolism MH - Leptospira interrogans/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 850904 DP - 1985 Apr IS - 0008-4050 TA - Can J Comp Med PG - 202-4 SB - M CY - CANADA IP - 2 VI - 49 JC - CI0 AA - Author EM - 8511 AB - Three monoclonal antibodies produced against Leptospira interrogans serovar pomona have been studied for their diagnostic usefulness. All three monoclonals reacted strongly in the enzyme-linked immunosorbent assay and indirect fluorescent antibody test with serovar pomona and did not react with serovars grippotyphosa, canicola, icterohaemorrhagiae and hardjo. PMID- 3893661 CU - 91 SO - Can J Comp Med 1985 Apr;49(2):202-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 85220486 AU - Chappel RJ AU - Adler B AU - Ballard SA AU - Faine S AU - Jones RT AU - Millar BD AU - Swainger JA TI - Enzymatic radioimmunoassay for detecting Leptospira interrogans serovar pomona in the urine of experimentally-infected pigs. LA - Eng MH - Animal MH - Immunoenzyme Techniques MH - Leptospira interrogans/*immunology MH - Leptospirosis/diagnosis/urine/*veterinary MH - Radioimmunoassay MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*diagnosis/urine PT - JOURNAL ARTICLE DA - 850725 DP - 1985 Apr IS - 0378-1135 TA - Vet Microbiol PG - 279-86 SB - M CY - NETHERLANDS IP - 3 VI - 10 JC - XBW AA - Author EM - 8509 AB - An enzymatic radioimmunoassay (ERIA) has been developed for detecting Leptospira interrogans serovar pomona in porcine urine. Four grower pigs were experimentally infected with serovar pomona. A total of 39 urine samples was collected, and ERIA was compared with dark ground microscopy (DGM) and culture for demonstrating leptospiruria. Of 20 samples positive by at least one technique, leptospires were detected by ERIA in 14, by culture in 16 and by DGM in 13. ERIA, unlike the other 2 methods, was suitable for use with urine which had been stored frozen for several months. PMID- 3890354 CU - 90 SO - Vet Microbiol 1985 Apr;10(3):279-86 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 86162065 AU - Karsenti G AU - Navarre L AU - Malan P AU - Mercadier B AU - Millet P AU - Esmenjaud E TI - [2 cases of bilateral acute necrotizing retinitis: 1 in icterohemorrhagic leptospirosis, the other caused by probable autoimmune involvement (bilateral acute retinal necrosis)] LA - Fre MH - Acute Disease MH - Antigen-Antibody Complex/analysis MH - *Autoimmune Diseases/immunology MH - Case Report MH - Child MH - Female MH - Human MH - Ischemia/diagnosis MH - Male MH - Middle Age MH - Necrosis MH - Retina/*pathology MH - Retinal Artery/pathology MH - Retinitis/*etiology/therapy MH - *Weil's Disease/diagnosis RN - 0 (Antigen-Antibody Complex) PT - JOURNAL ARTICLE DA - 860425 DP - 1985 Apr IS - 0081-1270 TA - Bull Soc Ophtalmol Fr PG - 501-10 CY - FRANCE IP - 4 VI - 85 JC - C40 EM - 8607 PMID- 3830462 CU - 92 TT - A propos de deux cas de retinite necrosante aigue bilaterale: l'un au cours d'une leptospirose icterohemorragique l'autre par atteinte auto- immune probable ("bilateral acute retinal necrosis"). SO - Bull Soc Ophtalmol Fr 1985 Apr;85(4):501-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85183040 AU - Thiermann AB AU - Handsaker AL AU - Moseley SL AU - Kingscote B TI - New method for classification of leptospiral isolates belonging to serogroup pomona by restriction endonuclease analysis: serovar kennewicki. LA - Eng MH - DNA Restriction Enzymes/pharmacology MH - DNA, Bacterial/*analysis MH - Leptospira/analysis/*classification RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 850617 DP - 1985 Apr IS - 0095-1137 TA - J Clin Microbiol PG - 585-7 SB - M CY - UNITED STATES IP - 4 VI - 21 JC - HSH AA - Author EM - 8508 AB - The genomes of leptospiral field isolates belonging to serogroup Pomona were analyzed and compared with those of type strains by cleavage with restriction endonucleases. This new classification method shows differences among these organisms not indicated by the conventional serological typing method. No differences were observed among isolates from the United States, Canada, and New Zealand. Although all isolates selected for this study had been serologically typed as belonging to serovar pomona, the restriction endonuclease analysis indicates that they belong to serovar kennewicki. kennewicki, a serovar of North American origin, has recently been eliminated from the official serovar list because it was found to be indistinguishable from serovar pomona by the serological method. PMID- 2985648 CU - 93 SO - J Clin Microbiol 1985 Apr;21(4):585-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 87248308 AU - Sternfeld M AU - Eliraz A AU - Nissim F TI - [Weil's disease with hemorrhagic pneumonitis due to Leptospira grippotyphosa] LA - Heb MH - Adult MH - Case Report MH - English Abstract MH - Hemorrhage/*etiology/therapy MH - Human MH - Male MH - Pneumonia/*etiology/therapy MH - Weil's Disease/*complications/therapy PT - JOURNAL ARTICLE DA - 870811 DP - 1985 Mar 15 IS - 0017-7768 TA - Harefuah PG - 292-4 CY - ISRAEL IP - 6 VI - 108 JC - FZF EM - 8710 PMID- 3843402 EA - A SO - Harefuah 1985 Mar 15;108(6):292-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 86032765 AU - Girio RJ AU - Yanaguita RM AU - Mathias LA TI - Comparative study of four saprophytic leptospira strains as screening antigens in the serodiagnosis of leptospirosis in water buffaloes (Bubalus bubalis). LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/*immunology MH - Brazil MH - Buffaloes/*immunology MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/immunology/*veterinary MH - Serotyping RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 851125 DP - 1985 Mar IS - 0377-0168 TA - Int J Zoonoses PG - 61-6 SB - M CY - TAIWAN IP - 1 VI - 12 JC - GTK AA - Author EM - 8602 AB - The profitability of four saprophytic leptospira strains (Buenos Aires, Patoc 1, Rufino and Sao Paulo) as polyvalent antigen in the serodiagnosis of leptospirosis in water buffaloes was studied by the microscopic agglutination test. From 104 examined sera tested against 16 pathogenic leptospira serotypes, 52 were positives and 52 were negatives. The results led to the conclusion that from four studied strains, Buenos Aires strain showed the best results when utilized in screening tests for the serodiagnosis of leptospirosis in water buffaloes. The other three strains showed a good specificity but their sensibilities were poor and therefore should not be recommended for diagnosing water buffalo leptospirosis. PMID- 4055269 CU - 91 SO - Int J Zoonoses 1985 Mar;12(1):61-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85263505 AU - Cacciapuoti B AU - Pinto A AU - Silva I TI - Antigenic population changes of Leptospira biflexa strains grown under the selective pressure of factorial antibodies. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*immunology MH - Antigens, Bacterial/*immunology MH - Antigens, Surface/*immunology MH - Immune Sera MH - Leptospira/classification/genetics/*immunology MH - Serotyping MH - *Variation (Genetics) RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Antigens, Surface) PT - JOURNAL ARTICLE DA - 850829 DP - 1985 Mar IS - 0022-1287 TA - J Gen Microbiol PG - 521-6 SB - M CY - ENGLAND VI - 131 ( Pt 3) JC - I87 AA - Author EM - 8511 AB - Serovars jequitaia and tororo of Leptospira biflexa were cultured in the presence of homologous factor serum containing factorial antibodies (FcAbs) to their major antigens. After 39 serial passages they were then re-tested to determine whether their major antigens had remained unchanged. It was found that each parent strain had been replaced by an antigenic variant. The disappearance of each parent strain and its replacement by an antigenic variant was attributed to the selective conditions imposed by FcAbs. The antigenic variants behaved like true mutants. They lacked the major serovar antigens of the parent strains and had acquired some major antigens similar to those of two different serovars, one of which belonged to the same serogroup as the parent strain and the other to a different serogroup. A comparison of the major antigens of the parent strains with those of their antigenic variants indicated that factorial antibodies may be used selectively to obtain antigenic variants with a predefined pattern of major antigens. PMID- 4020340 CU - 91 SO - J Gen Microbiol 1985 Mar;131 ( Pt 3):521-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 85245188 AU - Bao L AU - Dai BM TI - [Electron microscopy of the freeze-fracture study of pulmonary microvessels of guinea pigs in pulmonary diffuse haemorrhage due to leptospirosis] LA - Chi MH - Animal MH - Capillaries/ultrastructure MH - English Abstract MH - Freeze Fracturing MH - Guinea Pigs MH - Hemorrhage/etiology/pathology MH - Lung/*blood supply MH - Lung Diseases/etiology/pathology MH - Microscopy, Electron MH - Weil's Disease/complications/*pathology PT - JOURNAL ARTICLE DA - 850729 DP - 1985 Mar IS - 0253-4290 TA - Ssu Chuan I Hsueh Yuan Hsueh Pao PG - 37-40 CY - CHINA IP - 1 VI - 16 JC - VBT EM - 8510 PMID- 4012588 EA - A SO - Ssu Chuan I Hsueh Yuan Hsueh Pao 1985 Mar;16(1):37-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 85245187 AU - Hu QL AU - Yin QZ AU - Wu SR AU - Dai BM AU - Lei YD TI - [Relationship between the number of leptospires in blood, livers and lungs of guinea pigs and the pulmonary diffuse hemorrhage of leptospirosis] LA - Chi MH - Animal MH - Blood/microbiology MH - English Abstract MH - Guinea Pigs MH - Hemorrhage/etiology/*microbiology MH - Leptospira interrogans/*isolation & purification MH - Liver/microbiology MH - Lung/microbiology MH - Lung Diseases/etiology/*microbiology MH - Weil's Disease/complications/*microbiology PT - JOURNAL ARTICLE DA - 850729 DP - 1985 Mar IS - 0253-4290 TA - Ssu Chuan I Hsueh Yuan Hsueh Pao PG - 33-6 CY - CHINA IP - 1 VI - 16 JC - VBT EM - 8510 PMID- 4012587 EA - A SO - Ssu Chuan I Hsueh Yuan Hsueh Pao 1985 Mar;16(1):33-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 85245182 AU - Wang CX AU - Ye DN AU - Wu SR AU - Yin QZ AU - Dai BM TI - [Selection of hybridomas producing monoclonal antibodies against Leptospira icterohemorrhagiae serovar Lai strain 017] LA - Chi MH - Animal MH - Antibodies, Monoclonal/*biosynthesis MH - English Abstract MH - Female MH - Hybridomas/*immunology MH - IgG/analysis MH - IgM/analysis MH - Leptospira interrogans/*immunology MH - Mice MH - Mice, Inbred BALB C RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 850729 DP - 1985 Mar IS - 0253-4290 TA - Ssu Chuan I Hsueh Yuan Hsueh Pao PG - 11-4 CY - CHINA IP - 1 VI - 16 JC - VBT EM - 8510 PMID- 4012584 CU - 91 EA - A SO - Ssu Chuan I Hsueh Yuan Hsueh Pao 1985 Mar;16(1):11-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 85241417 AU - Te Brugge LA AU - Louw HN TI - Addition of rabbit serum to EMJH medium improves isolation of Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Blood MH - Culture Media MH - Leptospira interrogans/growth & development/*isolation & purification MH - Rabbits MH - Serum Albumin, Bovine RN - 0 (Culture Media) RN - 0 (Serum Albumin, Bovine) PT - JOURNAL ARTICLE DA - 850822 DP - 1985 Mar IS - 0030-2465 TA - Onderstepoort J Vet Res PG - 53-4 SB - M CY - SOUTH AFRICA IP - 1 VI - 52 JC - OI6 AA - Author EM - 8510 AB - The addition of 2% pooled rabbit serum to semi-solid commercial EMJH medium with EMJH enrichment and 0,5 mg of 5-fluorouracil per ml was found to enhance the growth rate and success of isolation of Leptospira interrogans serovar hardjo from bovine urine. Cultures made on media without serum had to be kept for more than 130 days before being discarded as negative. PMID- 4011158 CU - 91 SO - Onderstepoort J Vet Res 1985 Mar;52(1):53-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85241416 AU - Te Brugge LA AU - Dreyer T TI - Leptospira interrogans serovar hardjo associated with bovine abortion in South Africa. LA - Eng MH - Abortion, Septic/microbiology/veterinary MH - Abortion, Veterinary/*microbiology MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Pregnancy MH - South Africa PT - JOURNAL ARTICLE DA - 850822 DP - 1985 Mar IS - 0030-2465 TA - Onderstepoort J Vet Res PG - 51-2 SB - M CY - SOUTH AFRICA IP - 1 VI - 52 JC - OI6 AA - Author EM - 8510 AB - Leptospira interrogans serovar hardjo was isolated from urine from dairy cattle in the Onderstepoort area. This was the first successful isolation of this serovar as sole agent causing an abortion storm in the Republic of South Africa. Abortions occurred as early as at 4 months' gestation. PMID- 4011157 SO - Onderstepoort J Vet Res 1985 Mar;52(1):51-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [68 medline neighbors] UI - 85139910 AU - Roth RM AU - Gleckman RA TI - Human infections derived from dogs. LA - Eng MH - Animal MH - Bacterial Infections/transmission MH - Bites and Stings/complications/therapy MH - Brucellosis/transmission MH - Campylobacter Infections/transmission MH - Dirofilariasis/transmission MH - Dog Diseases/microbiology/*transmission MH - Dogs MH - Echinococcosis/transmission MH - Human MH - Leptospirosis/transmission MH - Rabies/prevention & control/transmission MH - Rocky Mountain Spotted Fever/transmission MH - Tetanus/prevention & control/transmission MH - Toxocariasis/transmission MH - Zoonoses/diagnosis/prevention & control/*transmission PT - JOURNAL ARTICLE DA - 850418 DP - 1985 Mar IS - 0032-5481 TA - Postgrad Med PG - 169-73, 176-8, 180 SB - A SB - M CY - UNITED STATES IP - 4 VI - 77 JC - PFK AA - Author EM - 8506 AB - Infected dogs, including those that appear healthy, have been implicated in the genesis of certain infectious disorders in humans. Failure to appreciate the epidemiologic features of these infections can result in delayed diagnosis and therapy, with occasional fatal results. Efforts directed toward patient education, frequent veterinarian examinations of household pets, and thorough hand washing after animal contact will reduce the incidence of dog-related infections in humans. PMID- 3975185 CU - 90 SO - Postgrad Med 1985 Mar;77(4):169-73, 176-8, 180 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 86001830 AU - Mailloux M AU - Dufresne Y TI - [The immunologic diagnosis of leptospirosis: comparison of the ELISA technic with the agglutination-lysis reaction] LA - Fre MH - *Agglutination Tests MH - Antigens, Bacterial/analysis MH - Comparative Study MH - English Abstract MH - *Enzyme-Linked Immunosorbent Assay MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 851028 DP - 1985 Mar IS - 0001-4079 TA - Bull Acad Natl Med PG - 363-7 CY - FRANCE IP - 3 VI - 169 JC - B8G EM - 8601 PMID- 3899306 CU - 91 TT - Le diagnostic immunologique des leptospiroses: comparaison de la technique ELISA a la reaction d'agglutination-lyse. EA - A SO - Bull Acad Natl Med 1985 Mar;169(3):363-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 85172414 AU - Pappas MG AU - Ballou WR AU - Gray MR AU - Takafuji ET AU - Miller RN AU - Hockmeyer WT TI - Rapid serodiagnosis of leptospirosis using the IgM-specific Dot-ELISA: comparison with the microscopic agglutination test. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/immunology MH - Comparative Study MH - *Enzyme-Linked Immunosorbent Assay MH - Human MH - IgG/analysis MH - IgM/analysis MH - *Immunoenzyme Techniques MH - Leptospira/immunology MH - Leptospira interrogans/immunology MH - Time Factors MH - Weil's Disease/*diagnosis/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 850501 DP - 1985 Mar IS - 0002-9637 TA - Am J Trop Med Hyg PG - 346-54 SB - A SB - M CY - UNITED STATES IP - 2 VI - 34 JC - 3ZQ AA - Author EM - 8507 AB - The dot enzyme-linked immunosorbent assay (Dot-ELISA) was compared to the microscopic agglutination test (MA test) for the diagnosis of human leptospirosis. Of 177 sera from 68 soldiers who trained in the Republic of Panama, 102 sera were positive in the MA test and 93 of these sera were positive in the IgM-specific Dot-ELISA. Incidence of infection was 50 of 68 patients with the MA test and 48 of 68 in the IgM Dot-ELISA. Five MA test-positive sera were reactive only in the IgG-specific Dot- ELISA, suggesting previous exposure. All 21 infecting serovars of Leptospira interrogans, as determined by positive reactions in the MA test or culture of blood and urine specimens, were reactive in the Dot- ELISA. Of 75 sera negative in the MA test, 61 were nonreactive in the Dot-ELISA. However, 9 of these 14 Dot-ELISA-positive/MA test-negative sera were acute samples from patients whose later sera were MA test- positive. Positive reactions in the IgM Dot-ELISA occurred in 2 of 30 control, 4 of 10 Lyme disease, 1 of 11 relapsing fever, and 1 of 8 yaws sera; 10 syphilis patient sera were nonreactive. The IgM-specific Dot- ELISA appears to be sensitive and specific for the serodiagnosis of acute leptospirosis. In addition, this rapid test is inexpensive, simple to perform, utilizes minute volumes of killed leptospiral antigen and is easily adaptable to field use. PMID- 3885773 CU - 91 SO - Am J Trop Med Hyg 1985 Mar;34(2):346-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 85142958 AU - Snoep JJ TI - [Mastitis--Leptospira hardjo--milker's fever] LA - Dut MH - Animal MH - Case Report MH - Cattle MH - Human MH - *Leptospirosis/transmission/veterinary MH - Male MH - Mastitis, Bovine/*etiology/transmission MH - Poxviridae Infections/*etiology PT - JOURNAL ARTICLE DA - 850408 DP - 1985 Feb 15 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 150-1 SB - M CY - NETHERLANDS IP - 4 VI - 110 JC - VRY EM - 8506 PMID- 2983454 CU - 96 TT - Mastitis--Leptospira hardjo--melkerskoorts. SO - Tijdschr Diergeneeskd 1985 Feb 15;110(4):150-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 85123587 AU - Waitkins S TI - Leptospirosis? [letter] LA - Eng MH - Animal MH - Guinea Pigs MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis PT - LETTER DA - 850328 DP - 1985 Feb 9 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 468 SB - A SB - M SB - X CY - ENGLAND IP - 6466 VI - 290 JC - B4X EM - 8506 PMID- 3918636 CU - 91 SO - Br Med J (Clin Res Ed) 1985 Feb 9;290(6466):468 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 85198739 AU - McColl KA AU - Whittington RJ TI - Leptospiral titres in wild platypuses (Ornithorhynchus anatinus) in New South Wales. LA - Eng MH - Animal MH - Australia MH - Leptospira/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Monotremata/*microbiology MH - Platypus/*microbiology PT - JOURNAL ARTICLE DA - 850619 DP - 1985 Feb IS - 0005-0423 TA - Aust Vet J PG - 66-7 SB - M CY - AUSTRALIA IP - 2 VI - 62 JC - 9IE EM - 8508 PMID- 3994609 CU - 90 SO - Aust Vet J 1985 Feb;62(2):66-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 85197068 AU - Thiermann AB AU - Handsaker AL TI - Experimental infection of calves with Leptospira interrogans serovar hardjo: conjunctival versus intravenous route of exposure. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/immunology/*transmission MH - Comparative Study MH - Conjunctiva/*microbiology MH - Enzyme-Linked Immunosorbent Assay MH - Injections, Intravenous/veterinary MH - Kidney/microbiology MH - Leptospira interrogans/immunology/isolation & purification MH - Urine/microbiology MH - Weil's Disease/immunology/transmission/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850612 DP - 1985 Feb IS - 0002-9645 TA - Am J Vet Res PG - 329-31 SB - M CY - UNITED STATES IP - 2 VI - 46 JC - 40C AA - Author EM - 8508 AB - Eight-month-old calves, housed under maximum isolation, were exposed to pathogenic Leptospira interrogans serovar hardjo by the conjunctival route or IV. One calf served as an unexposed control. Infection was monitored serologically (microscopic agglutination test and enzyme- linked immunosorbent assay; ELISA) and by leptospiral culture isolation from periodic urine samples and from the kidneys, epididymides, and aqueous humor collected at slaughter. Microscopic agglutination test titers of greater than or equal to 1:40 were detected among all IV exposed calves at postinoculation day (PID) 7 and among conjunctival exposed calves at PID 14. By ELISA, all IV exposed calves were positive by PID 3, whereas conjunctival exposed calves were positive at PID 14. The ELISA was more sensitive for the detection of antibodies against leptospires in cattle. Leptospires were isolated from the urine of 4 calves and from the kidney of 3 calves exposed by the conjunctival route, but not from IV exposed calves. The results indicated that the conjunctival route of exposure was a more natural and successful route for experimental infection of cattle with serovar hardjo. PMID- 3994099 CU - 91 SO - Am J Vet Res 1985 Feb;46(2):329-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [91 medline neighbors] UI - 85194925 AU - Grossklaus D TI - [Infection prevention in animal husbandry. A contribution to the improvement of the sanitary consumer protection] LA - Ger MH - Animal MH - *Animal Husbandry MH - Animals, Domestic MH - *Communicable Disease Control MH - English Abstract MH - Food Contamination/*prevention & control MH - *Food Microbiology MH - Germany, West MH - Legislation MH - Legislation, Veterinary MH - *Public Health MH - Salmonella Infections, Animal/prevention & control MH - Zoonoses/*prevention & control PT - JOURNAL ARTICLE DA - 850620 DP - 1985 Feb IS - 0174-3015 TA - Zentralbl Bakteriol Mikrobiol Hyg [B] PG - 225-40 SB - M CY - GERMANY, WEST IP - 2-3 VI - 180 JC - Y5R AA - Author EM - 8508 AB - The scientific and organizational development of an effective prophylaxis against infections in animal husbandry results from the fact that many zoonoses, like salmonellosis, campylobacteriosis, toxoplasmosis, leptospirosis, listeriosis, rickettsiosis (Q-Fever) and cysticercosis as well as certain important virus infections with regard to meat hygiene cannot be detected during official ante- and postmortem inspection. The cause of these infections is clinically inapparent and leaves no pathologic-anatomical lesions. Partly responsible for these latent infections is mass production with its specific forms of husbandry, particularly in poultry and pigs. The development of these animal production methods as well as the spread of the aforementioned zoonoses in man and animal is being discussed in this paper. The information on zoonoses is based on cases reported in accordance with the Federal Communicable Diseases Act and/or the regulations on notifiable animal diseases. The potential harmfulness to the consumer's health, especially in view of his food habits, is discussed in the light of the increase of foodborne infections and intoxications caused by Salmonella. Up until now, several regulations exist to keep causative agents of zoonoses away from animal farms. In view of the successful eradication of tuberculosis in cattle and brucellosis, it is recommended on a longterm basis, to eliminate those zoonoses from animal farms, which are of special importance from the meat-hygienic point of view. On a medium-term basis, examination of farm animals should be introduced voluntarily prior to the official ante- and postmortem inspection. It is of vital importance to establish the necessary diagnostic and practical conditions for the herd-tests. A recommendation worked out by the European Community for the examination of broiler-farms is welcomed as an example of prophylactic measures suitable for the improvement of consumer protection. PMID- 3993255 TT - Infektionsprophylaxe in der Nutztierhaltung Ein Beitrag zur Verbesserung des gesundheitlichen Verbraucherschutzes. EA - A SO - Zentralbl Bakteriol Mikrobiol Hyg [B] 1985 Feb;180(2-3):225-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85194284 AU - Ivakhnenko AG AU - Fomenko VS AU - Foka IN AU - Dorofeeva TN TI - [Clinical forms, diagnosis and treatment of leptospirosis] LA - Rus MH - Adult MH - Case Report MH - Combined Modality Therapy MH - Human MH - Leptospirosis/classification/*diagnosis/therapy MH - Male PT - JOURNAL ARTICLE DA - 850605 DP - 1985 Feb IS - 0026-9050 TA - Voen Med Zh PG - 39-41 CY - USSR IP - 2 JC - XGS EM - 8508 PMID- 3992943 TT - Klinicheskie formy, diagnostika i lechenie leptospiroza. SO - Voen Med Zh 1985 Feb;(2):39-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 85159530 AU - Terpstra WJ AU - Ligthart GS AU - Schoone GJ TI - ELISA for the detection of specific IgM and IgG in human leptospirosis. LA - Eng MH - Agglutination Tests MH - Antigens, Bacterial MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - IgG/*analysis MH - IgM/*analysis MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology MH - Time Factors MH - Weil's Disease/*immunology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 850426 DP - 1985 Feb IS - 0022-1287 TA - J Gen Microbiol PG - 377-85 SB - M CY - ENGLAND VI - 131 ( Pt 2) JC - I87 AA - Author EM - 8507 AB - ELISA was used to detect specific IgM and IgG in sera from humans with current or past leptospirosis. A serological pattern of a high IgM titre (greater than or equal to 1280), or moderately increased IgM (160- 640) in conjunction with a low IgG titre (less than or equal to 20), with serovar copenhageni antigen was characteristic for approximately two-thirds of the sera from serovar icterohaemorrhagiae patients obtained in the first two months of the disease. The antigen was the supernatant of a heated and centrifuged culture of leptospires. Antigens were prepared from serovars copenhageni, grippotyphosa, hardjo and patoc. Sera from patients with icterohaemorrhagiae, grippotyphosa and hardjo infections showed cross-reactivity when different antigens were used. In past infections the IgG titres were clearly higher with the homologous antigen. ELISA for IgM and IgG allows the rapid diagnosis of acute leptospirosis. PMID- 3981131 CU - 91 SO - J Gen Microbiol 1985 Feb;131 ( Pt 2):377-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 85132594 AU - Gill ON AU - Coghlan JD AU - Calder IM TI - The risk of leptospirosis in United Kingdom fish farm workers. Results from a 1981 serological survey. LA - Eng MH - Adult MH - Antibodies, Bacterial/analysis MH - *Fisheries MH - Great Britain MH - Human MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology/etiology MH - Occupational Diseases/*epidemiology MH - Risk MH - Time Factors RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850402 DP - 1985 Feb IS - 0022-1724 TA - J Hyg (Lond) PG - 81-6 SB - M CY - ENGLAND IP - 1 VI - 94 JC - IEF AA - Author EM - 8506 AB - Less than one per cent of serum samples taken from 257 fish farmers in 1981 had agglutinating antibodies to strains of Leptospira interrogans of serogroup Icterohaemorrhagiae at a titre of 30 or greater. Compared with the results from other serological surveys, this agglutinating antibody prevalence suggests that fish farming does not have a high occupational risk for leptospirosis. Between 1961 and 1981 the incidence in fish farmers was about 33 per 100000 person years at risk. During the same period the incidence in the general adult male population was 0.137 per 100000 person years at risk, so that fish farming had a moderately increased risk of Icterohaemorrhagiae serogroup infection (relative risk = 243). No one particular risk factor within fish farming could be reliably identified and therefore recommendations to reduce the risk can only be general. PMID- 3973382 CU - 91 SO - J Hyg (Lond) 1985 Feb;94(1):81-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85131664 AU - Fairbrother JM TI - Effects of products of autolysis of tissue and urine on the viability, morphology, and antigenicity of Leptospira interrogans serovar pomona. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - *Autolysis MH - Cattle MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification MH - Rabbits MH - Support, Non-U.S. Gov't MH - Urine/*microbiology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 850329 DP - 1985 Feb IS - 0095-1137 TA - J Clin Microbiol PG - 189-94 SB - M CY - UNITED STATES IP - 2 VI - 21 JC - HSH AA - Author EM - 8506 AB - The effect of the products of autolysis on Leptospira interrogans serovar pomona was investigated in bovine kidney tissues and urine inoculated with this organism. No viable leptospires were found at 24 h or subsequently after inoculation of kidney tissues or urine. Leptospires and their soluble antigens were rapidly destroyed in tissues stored at 20 degrees C and could not be detected by the fluorescent-antibody test and the enzyme-linked immunosorbent assay. On the other hand, leptospires were detectable by dark-field microscopy and fluorescent-antibody test 38 days after addition to urine. The rate of destruction proceeded less rapidly in tissues stored at 4 degrees C. Under the conditions of this study, soluble leptospiral antigen levels decreased less rapidly than did the number of detectable leptospires. Similarly, breakdown of leptospires, demonstrated by dark-field microscopy and fluorescent-antibody test, progressed during the first 5 days after inoculation of urine, when levels of soluble leptospiral antigen remained constant. Although the number of intact leptospires was markedly reduced after freezing of tissues at -20 degrees C, soluble leptospiral antigen levels remained unaltered. Neither intact leptospires nor their soluble antigens were detected after preservation of tissues in Formalin. However, formolization of urine delayed the destruction of leptospires and increased the levels of soluble leptospiral antigen during at least the first 5 days after inoculation. These results indicate that assays such as the enzyme-linked immunosorbent assay should be useful for the detection of soluble leptospiral antigens in urine and in autolyzing tissues such as those taken from a bovine fetus aborted as a result of leptospiral infection. PMID- 3882747 CU - 91 SO - J Clin Microbiol 1985 Feb;21(2):189-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 85195012 AU - Chernukha IuG AU - Evdokimova OA AU - Anan'ina IuV AU - Chekhovich AV TI - [Differences in the susceptibility of field mice from the Altai Territory and Moscow Province to Leptospira of serovar mozdok and serogroup Pomona] LA - Rus MH - Aging MH - Animal MH - Antibodies, Bacterial/analysis MH - Carrier State/microbiology MH - Comparative Study MH - Disease Reservoirs MH - Disease Susceptibility MH - English Abstract MH - Female MH - Leptospira/classification/immunology/*pathogenicity MH - Leptospirosis/microbiology MH - Male MH - Muridae/*microbiology MH - Pregnancy MH - Russia MH - Serotyping MH - Sex Characteristics MH - Siberia RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850619 DP - 1985 Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 45-9 SB - M CY - USSR IP - 2 JC - Y9O AA - Author EM - 8508 AB - Adult striped field mice (Apodemus agrarius) caught in the Altai region proved to be insusceptible to experimental infection when inoculated with Leptospira of serovar mozdok, serogroup Pomona. In pregnant females, though infected with this organism, no leptospiruria was observed. At the same time nonpubescent animals became Leptospira carriers, females becoming carriers 4.5 times more frequently than males. The formation of antibodies to Leptospira in the test rodents was poorly pronounced and did not depend on their sex, age, physiological state and the presence of renal leptospirosis. But all adult striped field mice belonging to the population of the Moscow region became Leptospira carriers in such experiments. PMID- 3158138 CU - 92 TT - Razlichiia v vospriimchivosti polevykh myshei Altaiskogo kraia i Moskovskoi oblasti k leptospiram serovara mozdok serogruppy Pomona. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1985 Feb;(2):45-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85194923 AU - Mayr A TI - [Vaccination of animals and human health] LA - Ger MH - Animal MH - Animals, Domestic MH - Dog Diseases/prevention & control MH - Dogs MH - English Abstract MH - *Health MH - Human MH - Influenza A Virus/genetics MH - Orthomyxoviridae Infections/prevention & control/veterinary MH - Rabies/epidemiology/prevention & control/veterinary MH - Reoviridae Infections/prevention & control/veterinary MH - Salmonella Infections/prevention & control MH - Salmonella Infections, Animal/prevention & control MH - Vaccination/adverse effects/*veterinary MH - Variation (Genetics) MH - Zoonoses/*prevention & control PT - JOURNAL ARTICLE DA - 850620 DP - 1985 Feb IS - 0174-3015 TA - Zentralbl Bakteriol Mikrobiol Hyg [B] PG - 175-89 SB - M CY - GERMANY, WEST IP - 2-3 VI - 180 JC - Y5R AA - Author EM - 8508 AB - Prophylactic immunization of animals against obligat and nonobligat pathogenic zoonoses benefit human health in many ways both directly and indirectly. Typical examples of a direct protective effect are the vaccinations of dogs, cats and foxes against rabies as well as the vaccinations against respiratory diseases in cows, horses, dogs and cats to which the most varied species of pathogens of noncompulsory zoonoses contribute. A considerable contribution to the protection of human health is made by the vaccination against salmonellosis and leptospirosis, against vesicular stomatitis, American equine encephalitis and against other zoonoses spread by arthropods, against ecthyma and stomatitis papulosa as well as against brucellosis, anthrax, Q-fever, Newcastle disease and foot-and-mouth disease. The indirect effects of prophylactic vaccination of animals on human health are very complex and still need investigation. An example of this are the vaccinations of animals against human and animal influenza A viruses which can inhibit hybridisation and recombination between human and animal influenza viruses in an ecological system. Occasionally prophylactic vaccinations of animals can do harm to human health. This is invariably a rare incidence in immuno-suppressed persons caused by live vaccines i.e. prophylactic vaccination against Newcastle disease in fowl or against orthopox in animals by the use of the common vaccinia strains, after compulsory vaccination for humans had been cancelled. Prophylactic vaccinations of animals must be constantly followed up and their action on human health must be checked. In the case of positive results prophylactic vaccinations must be carried out selectively and in a wide range. PMID- 2986381 CU - 96 TT - Schutzimpfung beim Tier und Gesundheit des Menschen. EA - A SO - Zentralbl Bakteriol Mikrobiol Hyg [B] 1985 Feb;180(2-3):175-89 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 85140101 AU - Duval G AU - Michault A AU - Corbin JC AU - Arvin-Berod C AU - Carre P AU - Genin R TI - [Acute respiratory distress syndrome disclosing icterohemorrhagic leptospirosis. 2 cases (letter)] LA - Fre MH - Adult MH - Case Report MH - Human MH - Male MH - Respiratory Distress Syndrome, Adult/*etiology MH - Weil's Disease/*complications PT - LETTER DA - 850322 DP - 1985 Jan 26 IS - 0755-4982 TA - Presse Med PG - 167 SB - M SB - X CY - FRANCE IP - 3 VI - 14 JC - PMT EM - 8506 PMID- 3156353 CU - 92 TT - Syndrome de derresse respiratoire aigue revelateur d'une leptospirose icterohemorragique. 2 observations. SO - Presse Med 1985 Jan 26;14(3):167 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 85169686 AU - Meszaros J AU - Stipkovits L AU - Antal T AU - Szabo I AU - Veszely P TI - Eradication of some infectious pig diseases by perinatal tiamulin treatment and early weaning. LA - Eng MH - Administration, Oral MH - Animal MH - Antibiotics/administration & dosage/*therapeutic use MH - Diterpenes/administration & dosage/therapeutic use MH - Female MH - Mycoplasma Infections/prevention & control/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/prevention & control/*veterinary MH - Swine MH - Swine Diseases/mortality/*prevention & control MH - Time Factors MH - Treponemal Infections/prevention & control/*veterinary MH - *Weaning RN - 0 (Antibiotics) RN - 0 (Diterpenes) RN - 55297-95-5 (tiamulin) PT - JOURNAL ARTICLE DA - 850426 DP - 1985 Jan 5 IS - 0042-4900 TA - Vet Rec PG - 8-12 SB - M CY - ENGLAND IP - 1 VI - 116 JC - XBS AA - Author EM - 8507 AB - From 10 days before the expected date of farrowing onwards, 97 sows infected by Mycoplasma hyopneumoniae and Treponema hyodysenteriae were given tiamulin daily at a dosage of 20 mg/kg bodyweight via the feed. Three days before farrowing the sows were washed with a disinfectant and transferred to an isolated farrowing house. The sucking piglets remained with their dams for five days, during which time the sows continued to receive the tiamulin-containing feed. The sucking piglets also received tiamulin daily at a dosage of 30 mg/kg bodyweight. At six days old the weaker piglets of the litter were returned to the original herd, together with their dams. A total of 574 piglets of about 1.5 kg bodyweight each were transferred to an isolated and previously disinfected pig farm and reared there. A total of 13.8 per cent of these pigs died by 50 days old. On the isolated farm, 10.9 per cent of the 829 second generation piglets born to the 101 first generation sows, died up to the age of 50 days. On the isolated farm about 2000 pigs were subjected to repeated clinical, pathological and laboratory examinations for M hyopneumoniae, T hyodysenteriae, Aujeszky's disease virus and Leptospira species during the three year period of study. No evidence of infection with any of these agents was found in the 2000 pigs of the isolation herd, although the original sow herd had been latently infected by these pathogens. No maternally derived antibodies against these pathogens were detectable in sera of three-day-old sucking piglets of the second and third generations. PMID- 3984171 CU - 92 SO - Vet Rec 1985 Jan 5;116(1):8-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 86106494 AU - Soulayrol L AU - Raoult D AU - Harle JR AU - Mailloux M AU - Gallais H AU - Casanova P TI - [Meningitis and meningoencephalitis caused by Leptospira. Apropos of 5 cases seen in Marseille during 1984] LA - Fre MH - Adult MH - Africa MH - Aged MH - Case Report MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - France MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Meningitis/diagnosis/epidemiology/*etiology MH - Meningoencephalitis/diagnosis/epidemiology/*etiology MH - Singapore PT - JOURNAL ARTICLE DA - 860326 DP - 1985 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 563-73 SB - M CY - FRANCE IP - 5 VI - 78 JC - C4G AA - Author EM - 8605 AB - The authors report 5 cases of leptospirosis with neurological symptoms. One case of polyradiculoneuritis, one case of meningoencephalitis, two of meningitis and a case a meningeal syndrome were observed. Three of these cases were contracted near Marseille, one in Singapour and one in Comores. The diagnosis was done by serology and the evolution was good. PMID- 4085096 CU - 88 TT - Meningites et meningoencephalites a Leptospira. A propos de cinq cas observes a Marseille au cours de l'annee 1984. EA - A SO - Bull Soc Pathol Exot Filiales 1985;78(5):563-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 86079824 AU - Raoult D AU - Mailloux M AU - De Chanville F AU - Chaudet H TI - [Seroepidemiologic study on leptospirosis in the Camargue region] LA - Fre MH - Adolescence MH - Adult MH - Aged MH - Child MH - English Abstract MH - Female MH - France MH - Human MH - Leptospira canicola MH - Leptospira interrogans MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 860217 DP - 1985 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 439-45 SB - M CY - FRANCE IP - 4 VI - 78 JC - C4G AA - Author EM - 8604 AB - The damp environment and density of animal population in Camargue are good arguments for the study of leptospirosis. A serological and epidemiological survey on 642 blood samples revealed 36 (5.6%) with significant antibody titers. Icterohaemorrhagiae is followed by Canicola, Grippotyphosa, Australis and Ballum... The most endemic area is not Camargue but the area situated at the northeast (Basse-Durance). Women are twice more affected than men. These two results are not consistent with our initial hypothesis. It is always advisable to seek the etiology of fevers of unknown origin. PMID- 4075464 CU - 88 TT - Etude sero-epidemiologique sur la leptospirose en region camarguaise. EA - A SO - Bull Soc Pathol Exot Filiales 1985;78(4):439-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 86060363 AU - Chee HD AU - Ossenkoppele GJ AU - Bronsveld W AU - Thijs LG TI - Adult respiratory distress syndrome in leptospira icterohaemorrhagiae infection. LA - Eng MH - Case Report MH - Human MH - Male MH - Middle Age MH - Respiratory Distress Syndrome, Adult/diagnosis/*etiology MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 851230 DP - 1985 IS - 0342-4642 TA - Intensive Care Med PG - 254-6 SB - M CY - UNITED STATES IP - 5 VI - 11 JC - H2J AA - Author EM - 8603 AB - A 55-year-old man was admitted to our Intensive Care Unit with symptoms and signs of Weil's disease. Respiratory failure developed. Radiological and haemodynamic features were consistent with the adult respiratory distress syndrome. The patient recovered after mechanical ventilation with positive end-expiratory pressure. This case confirms that the adult respiratory distress syndrome may occur in leptospirosis. PMID- 4067061 SO - Intensive Care Med 1985;11(5):254-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 86047924 AU - Montoliu J AU - Coca A AU - Martinez-Orozco F AU - Darnell A AU - Subias R AU - Revert L TI - Acute renal failure complicating viral hepatitis in the absence of severe hepatic insufficiency. LA - Eng MH - Adult MH - Aged MH - Creatinine/blood MH - Female MH - Hepatitis, Viral, Human/*complications/physiopathology MH - Human MH - Kidney Failure, Acute/*etiology/physiopathology MH - Liver/physiopathology MH - Male MH - Middle Age MH - Sodium/urine RN - 60-27-5 (Creatinine) RN - 7440-23-5 (Sodium) PT - JOURNAL ARTICLE DA - 851209 DP - 1985 IS - 0250-8095 TA - Am J Nephrol PG - 372-4 SB - M CY - SWITZERLAND IP - 5 VI - 5 JC - 3MB AA - Author EM - 8602 AB - Four patients (2 were HBsAg positive) with acute icteric viral hepatitis (VH) developed acute renal failure (ARF) in the course of their illness and in the absence of other complications. Their peak serum creatinine values (4.7-10, mean 7 mg/dl) were reached either before or simultaneously with their maximum serum aminotransferase values (1,390-2730, mean 2,032 mU/ml). Apart from VH no other factors responsible for precipitating ARF could be identified. In the HBsAg- negative patients, serological investigations for infectious mononucleosis, cytomegalovirus infection, and leptospirosis were negative. In 2 patients liver biopsy showed changes consistent with VH. Proteinuria was absent in all cases, making glomerulonephritis unlikely. The urinary sodium excretion was uniformly high (57-104, mean 78 mmol/l in random samples). Two patients required short courses of dialysis. All cases recovered completely with return of serum creatinine to normal values after a mean duration of 25 days. After a normal serum creatinine level had been achieved, 1 case was lost to follow-up, and the other 3 cases maintain normal renal and liver function tests 9 months (mean) after the initial episode. Otherwise uncomplicated VH is a potential cause of ARF, even in the absence of severe hepatic insufficiency. The mechanism of ARF in VH is unknown, but vasoconstriction phenomena induced by endotoxemia might contribute. PMID- 4061505 SO - Am J Nephrol 1985;5(5):372-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 86017758 AU - Anusz Z TI - [Brucellosis and other zoonoses--1983] LA - Pol MH - Adolescence MH - Adult MH - Animal MH - Anthrax/epidemiology MH - Brucellosis/*epidemiology MH - Brucellosis, Bovine/epidemiology MH - Cattle MH - English Abstract MH - Female MH - Human MH - Leptospirosis/epidemiology MH - Listeria Infections/epidemiology MH - Male MH - Middle Age MH - Poland MH - Toxoplasmosis/epidemiology MH - Tularemia/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 851104 DP - 1985 IS - 0033-2100 TA - Przegl Epidemiol PG - 157-65 CY - POLAND IP - 1 VI - 39 JC - Q8T EM - 8601 PMID- 4048495 CU - 88 TT - Bruceloza i inne choroby odzwierzece--1983 rok. EA - A SO - Przegl Epidemiol 1985;39(1):157-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85214121 AU - Hanvanich M AU - Moollaor P AU - Suwangool P AU - Sitprija V TI - Hemolytic uremic syndrome in leptospirosis bataviae. LA - Eng MH - Case Report MH - Creatinine/blood MH - Hemolytic-Uremic Syndrome/*complications/physiopathology MH - Human MH - Kidney/physiopathology MH - Leptospirosis/*complications/physiopathology MH - Male MH - Middle Age RN - 60-27-5 (Creatinine) PT - JOURNAL ARTICLE DA - 850724 DP - 1985 IS - 0028-2766 TA - Nephron PG - 230-1 SB - M CY - SWITZERLAND IP - 2 VI - 40 JC - NW8 AA - Author EM - 8509 AB - Hemolytic uremic syndrome was observed in a 46-year-old man who had leptospirosis. Renal failure was severe with a prolonged clinical course. Despite clinical recovery there was residual renal damage indicated by mildly elevated serum creatinine. This is the first report of hemolytic uremic syndrome in leptospirosis. PMID- 4000352 SO - Nephron 1985;40(2):230-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 85193528 AU - Everard CO AU - Hayes RJ AU - Fraser-Chanpong GM TI - A serosurvey for leptospirosis in Trinidad among urban and rural dwellers and persons occupationally at risk. LA - Eng MH - Adult MH - Age Factors MH - Antibodies, Bacterial/analysis MH - Behavior MH - Environment MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Occupations MH - Rural Population MH - Sex Factors MH - Support, Non-U.S. Gov't MH - Trinidad and Tobago MH - Urban Population RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850620 DP - 1985 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 96-105 SB - M CY - ENGLAND IP - 1 VI - 79 JC - WBU AA - Author EM - 8508 AB - A survey for leptospiral antibodies was made of 1,375 persons in northern Trinidad between mid-1977 and mid-1978. The subjects were employees in seven occupational categories thought to entail a high risk of exposure to leptospires, and members of the general population of three rural and two urban communities. They were questioned inter alia about their leisure and occupational activities, household water supply and effluent, and contact with animals. Leptospiral infection was found to be widespread in the general population but not primarily associated with employment. Among the occupational groups the highest prevalence of antibodies was found in sugar-cane workers (45% infected), while among the communities prevalence was highest in the rural village of Cacandee (37%) and lowest in Woodbrook (Port-of-Spain) (5%). Keeping cattle, hunting and walking barefoot in the countryside were significantly associated with leptospiral serology. Over-all, serogroups Icterohaemorrhagiae and Autumnalis each accounted for about 25% of the seropositives in the general population. Among the occupational groups Autumnalis was the most commonly found (36%). It accounted for 42% of the seropositive sugar-cane workers and 57% of the seropositive rice farmers. PMID- 3992647 CU - 91 SO - Trans R Soc Trop Med Hyg 1985;79(1):96-105 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [83 medline neighbors] UI - 85193241 AU - Matthes S TI - [Vaccination of rabbits and fur animals] LA - Ger MH - Animal MH - Bacterial Infections/prevention & control/veterinary MH - *Carnivora MH - *Chinchilla MH - English Abstract MH - *Foxes MH - *Mink MH - *Rabbits MH - Vaccination/*veterinary MH - Virus Diseases/prevention & control/veterinary PT - JOURNAL ARTICLE DA - 850603 DP - 1985 IS - 0303-6286 TA - Tierarztl Prax PG - 107-12 SB - M CY - GERMANY, WEST IP - 1 VI - 13 JC - VS4 AA - Author EM - 8508 AB - Short survey of vaccination programmes for rabbits and fur animals and of vaccines, available in Western Germany. Rabbits: myxomatosis, pasteurella infection, dysenteria; mustelides (mink, polecat a.o.): distemper, virus enteritis, botulism, pseudomonas infection; fox: leptospirosis, distemper, fox encephalitis; ocelot: panleukopenia; chinchilla: pseudomonas infection, coli infection, yersinia infection. PMID- 3992574 TT - Schutzimpfungen bei Kaninchen und Pelztieren. EA - A SO - Tierarztl Prax 1985;13(1):107-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 86234620 AU - Carre P AU - Arvin-Berod C AU - Duval G AU - Michault A TI - [Predominant pulmonary manifestations in leptospirosis icterohemorrhagica] LA - Fre MH - Adolescence MH - Adult MH - Bronchopneumonia/etiology MH - Bronchoscopy MH - Carbon Dioxide/blood MH - English Abstract MH - Hemoptysis/etiology MH - Human MH - Lung/pathology/radiography MH - Male MH - Respiratory Distress Syndrome, Adult/etiology MH - Respiratory Tract Diseases/blood/*etiology/radiography MH - Weil's Disease/blood/*complications RN - 124-38-9 (Carbon Dioxide) PT - JOURNAL ARTICLE DA - 860627 DP - 1985 TA - Rev Mal Respir PG - 343-9 SB - M CY - FRANCE IP - 6 VI - 2 JC - RZ9 AA - Author EM - 8609 AB - 14 cases of leptospirosis ictero-haemorrhagica observed on Reunion island with predominant or isolated pulmonary symptoms are described. Hospitalisation was motivated in every case by haemoptysis, at times profuse, which occurred in patients with fever and myalgia. The chest radiographs revealed an alveolar and/or a bilateral alveolar pattern of variable severity. In spite of the importance of chest radiography port raying an extensive and serious pneumonia in one case out of every two, the outcome was favourable with a mean time lag of one week. In three cases, an adult respiratory distress syndrome (ARDS) was seen requiring assisted ventilation and one death occurred. The diagnosis of leptospirosis may be considered, even in countries of low endemicity, in a case pneumonia with extensive haemoptysis or an adult respiratory distress syndrome whose cause is not established by the usual tests. PMID- 3939042 CU - 91 TT - Manifestations pulmonaires predominantes au cours des leptospiroses ictero-hemorragiques. EA - A SO - Rev Mal Respir 1985;2(6):343-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 86260980 AU - Atienzar Cabrera E AU - Espino Llerena R AU - Lopez Acosta C AU - Sed Fernandez O AU - Alonso Bravo L TI - [A leptospirosis outbreak in the provinces of Camaguey and Las Tunas: serologic diagnosis, clinical characteristics and isolation of the microorganism] LA - Spa MH - Cuba MH - Disease Outbreaks/*epidemiology MH - English Abstract MH - Human MH - Leptospirosis/diagnosis/*epidemiology/etiology PT - JOURNAL ARTICLE DA - 860806 DP - 1985 Jan-Apr IS - 0375-0760 TA - Rev Cubana Med Trop PG - 105-12 CY - CUBA IP - 1 VI - 37 JC - RPX EM - 8610 RO - M:STD PMID- 3915375 LR - 920817 CU - 90 TT - Brote de leptospirosis en las provincias de Camaguey y Las Tunas: diagnostico serologico, caracteristicas clinicas y aislamiento del microorganismo. EA - A SO - Rev Cubana Med Trop 1985 Jan-Apr;37(1):105-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 86178782 AU - Mailloux M AU - Raoult D AU - Chaudet H TI - [Surveillance of icterohemorrhagic leptospirosis in France (1974-1983)] LA - Fre MH - English Abstract MH - France MH - Human MH - Immunologic Techniques MH - Seasons MH - Weil's Disease/diagnosis/*epidemiology PT - JOURNAL ARTICLE DA - 860522 DP - 1985 IS - 0398-7620 TA - Rev Epidemiol Sante Publique PG - 425-31 SB - M CY - FRANCE IP - 6 VI - 33 JC - RST AA - Author EM - 8607 AB - In France, between 1974 and 1983, 1 194 diagnoses of L. icterohaemorrhagiae leptospirosis were confirmed serologically at Pasteur Institute (Paris), WHO Reference Center. The number of cases diagnosed each year rose from 74 in 1974 to 277 in 1983. The annual incidence in 1983 was 0.55 per 100 000. The temporal distribution shows that 25% of cases were in August and 63% between July and October. Two areas have a greater incidence: the South West and the East. The departments near the sea of the South East, the North and the West have the lowest incidence. PMID- 3914013 CU - 90 TT - Surveillance de la leptospirose du groupe icterohaemorrhagiae en France (1974-1983). EA - A SO - Rev Epidemiol Sante Publique 1985;33(6):425-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [70 medline neighbors] UI - 86071024 AU - Tareeva IE AU - Lazovskis IR TI - [Tubulointerstitial nephropathies] LA - Rus MH - Adolescence MH - Bacterial Infections/complications MH - Case Report MH - Drug Therapy/adverse effects MH - Endocarditis, Bacterial/complications MH - English Abstract MH - Human MH - Hyperglycemia/complications MH - Hypokalemia/complications MH - Leptospirosis/complications MH - Lupus Erythematosus, Systemic/complications MH - Male MH - Nephritis, Interstitial/chemically induced/*etiology/immunology MH - Virus Diseases/complications PT - JOURNAL ARTICLE PT - REVIEW DA - 851226 DP - 1985 IS - 0040-3660 TA - Ter Arkh PG - 20-5 SB - M CY - USSR IP - 6 VI - 57 JC - VLU AA - Author EM - 8603 AB - The term tubulointerstitial nephropathy (TIN) means a renal disease, during which the tubules and interstice form a substrate of the primary injury or a substrate whose involvement is dominating in the disease clinical picture. The incidence of TIN is fairly high, with different etiology and pathogenesis. Drug, virus, bacterial and immune patterns are among the most common types of acute TIN. It is shown that the incidence of chronic drug TIN ranges from 0.2% among urban population to 0.6% among rural population. The incidence and gravity of renal injuries in hyperuricemia depend on the blood uric acid content. Study of the incidence and character of TIN in hypercalcemia in patients with sarcoidosis, hyperparathyrosis and multiple myeloma demonstrates the character of tubulointerstitial lesions to depend on the structure of paraprotein. In systemic lupus erythematosus, tubulointerstitial lesions are detected in 50% of cases. Such a comprehensive treatment of TIN opens up new vistas in the prophylaxis and therapy of this illness. RF - 28 PMID- 3906989 CU - 90 TT - Tubulointerstitsial'nye nefropatii. EA - A SO - Ter Arkh 1985;57(6):20-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 85183907 AU - Kiktenko VS TI - Influence of the mechanism of transmission of the infective agent on the aetiological structure of leptospiral foci. LA - Eng MH - Animal MH - Animals, Domestic MH - Animals, Wild MH - Antigens, Bacterial/classification MH - Comparative Study MH - *Disease Reservoirs/veterinary MH - Genitalia/microbiology MH - Human MH - Leptospira/classification/immunology/pathogenicity MH - Leptospirosis/etiology/*transmission/veterinary MH - Serotyping MH - Species Specificity RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE PT - REVIEW DA - 850529 DP - 1985 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 77-82 SB - M CY - CZECHOSLOVAKIA IP - 1 VI - 29 JC - IEV AA - Author EM - 8508 AB - It has been demonstrated that the differences observed in the aetiological structure of the individual foci of leptospirosis can be explained not only by the affinity of leptospiral serogroups to certain animal species, but also by different mechanisms of transmission of the causative agent of leptospiral infection which can be transferred both by sexual and alimentary routes (in water). It has been demonstrated that mostly one serotype of leptospires predominates in natural foci of leptospirosis, but several in anthropurgic ones. In the author's opinion, leptospiral infection in natural foci is mainly spread by the sexual route through the background species of animals--carriers of leptospirosis, and by the alimentary route in the anthropurgic foci. It is presumed that leptospires of the serogroups Javanica, Australis, Icterohaemorrhagiae, transmitted by the shrew-mice, hedgehogs and rats by the sexual route, are by their origin "ancient" serogroups of leptospires while the serogroups of leptospires isolated from domestic animals, showing predominantly the alimentary route of transmission of infection in the focus, are representatives of the "younger" forms of the evolutional development of leptospires. RF - 37 PMID- 3886786 CU - 91 SO - J Hyg Epidemiol Microbiol Immunol 1985;29(1):77-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 85177211 AU - Mailloux M TI - [Identification of the first human Leptospira strain in the island of La Reunion] LA - Fre MH - Adult MH - Case Report MH - English Abstract MH - Human MH - Immunologic Techniques MH - Indian Ocean Islands MH - Leptospira interrogans/*isolation & purification MH - Male MH - Weil's Disease/diagnosis/immunology/*microbiology PT - JOURNAL ARTICLE DA - 850617 DP - 1985 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 28-30 SB - M CY - FRANCE IP - 1 VI - 78 JC - C4G AA - Author EM - 8508 AB - The first Leptospira strain of the island of La Reunion isolated from a patient hospitalized at Saint-Pierre, is identified L. Icterohaemorrhagiae icterohaemorrhagiae. The importance and severity of leptospiroses in the island of La Reunion are to be emphasized. PMID- 3886179 CU - 90 TT - Identification de la premiere souche de leptospires d'origine humaine a l'ile de la Reunion. EA - A SO - Bull Soc Pathol Exot Filiales 1985;78(1):28-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85170731 AU - Verovenko OV TI - [A landmark in science (on the 90th anniversary of the birth of V. I. Terskikh)] LA - Rus MH - History of Medicine, 19th Cent. MH - History of Medicine, 20th Cent. MH - Human MH - Leptospirosis/history MH - Portraits MH - Russia (Pre-1917) MH - USSR PT - HISTORICAL ARTICLE PT - BIOGRAPHY PT - JOURNAL ARTICLE DA - 850509 DP - 1985 Jan IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 102-4 SB - M CY - USSR IP - 1 JC - Y9O EM - 8507 PMID- 3885638 CU - 96 PS - Terskikh VI TT - Sled v nauke (k 90-letiiu so dnia rozhdeniia V. I. Terskikh). SO - Zh Mikrobiol Epidemiol Immunobiol 1985 Jan;(1):102-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85056324 AU - Lukehart SA AU - Tam MR AU - Hom J AU - Baker-Zander SA AU - Holmes KK AU - Nowinski RC TI - Characterization of monoclonal antibodies to Treponema pallidum. LA - Eng MH - Animal MH - *Antibodies, Monoclonal MH - Antigens, Bacterial/*analysis MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Fluorescent Antibody Technique MH - Male MH - Mice MH - Mice, Inbred BALB C MH - Rabbits MH - Species Specificity MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Testis/immunology/microbiology MH - Treponema/immunology MH - Treponema pallidum/*immunology/isolation & purification RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE ID - AI 12192/AI/NIAID DA - 850122 DP - 1985 Jan IS - 0022-1767 TA - J Immunol PG - 585-92 SB - A SB - M SB - X CY - UNITED STATES IP - 1 VI - 134 JC - IFB AA - Author EM - 8503 AB - Thirteen hybrid cell lines which produce mouse monoclonal antibodies to Treponema pallidum, the causative agent of syphilis, have been established. All of the monoclonal antibodies react with T. pallidum, Nichols strain, in ELISA and in immunofluorescence assays, but do not react with normal rabbit testicular tissue in the ELISA. Two of these antibodies were demonstrated to react with the nonpathogenic treponemes T. phagedenis, biotype Reiter, T. refringens (Noguchi strain), T. vincentii, and T. denticola (strains 11 and W), as well as with Borrelia recurrentis, Leptospira interrogans, serogroup Canicola, and the swine pathogen T. hyodysenteriae. The remaining 11 antibodies react with four recently isolated strains of T. pallidum, but with none of the related nonpathogens nor with Borrelia or Leptospira. Thus, our results to date indicate that these monoclonal antibodies may identify antigenic determinants that are specific either for T. pallidum alone or for those treponemes which are pathogenic for humans. The molecular specificities of six of the 13 antibodies were determined by Western blotting. We anticipate potential usefulness of these antibodies in the investigation of the antigenic structure of T. pallidum, the taxonomic study of the pathogenic and nonpathogenic treponemes, and in the diagnosis of syphilis. PMID- 3880576 CU - 96 SO - J Immunol 1985 Jan;134(1):585-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [77 medline neighbors] UI - 88069281 AU - Giraudo JA AU - Dauria PG AU - de la Cruz JP AU - Bagnat E TI - [Anti-leptospira and anti-brucella agglutinins in hares (Lepus europaeus) from Rio Cuarto Department, Province of Cordoba] LA - Spa MH - Agglutinins/*analysis MH - Animal MH - Argentina MH - Brucella/*immunology MH - Disease Vectors MH - English Abstract MH - Lagomorpha/*immunology MH - Leptospira/*immunology MH - Mammals/*immunology RN - 0 (Agglutinins) PT - JOURNAL ARTICLE DA - 880112 DP - 1985 IS - 0325-7541 TA - Rev Argent Microbiol PG - 221-3 SB - M CY - ARGENTINA IP - 4 VI - 17 JC - QZ8 AA - Author EM - 8803 AB - Seventy-seven anti-brucella and 42 anti-leptospira agglutinin serum levels of hares in Rio Cuarto district of Cordoba Province were studied. For brucella, only one sample showed incomplete reaction at a 1:25 dilution. The isolation of brucella from liver, spleen and gastro- hepatic lymph node in this animal was negative. In the 42 serum samples examined for L. pomona, L. wolffi, L. ballum, L. hardjo, L. pyrogenes and L. grippotiphosa, 6 reacted at a dilution of 1:100 with L. ballum serovar and 1 reacted up to 1:200 dilution with L. wolffi serovar. These results indicate that the hare does not play any important role as reservoir of pathogenic brucella in this area. Meanwhile, it could act as potential reservoir for pathogenic leptospira. AD - Departamento de Patologia Animal, Facultad de Agronomia y Veterinaria, Universidad Nacional de Rio Cuarto, Argentina. PMID- 3870659 CU - 91 NP - X TT - Aglutininas anti-leptospira y anti-brucella en liebres (Lepus europaeus) del departamento de Rio Cuarto, provincia de Cordoba. EA - A SO - Rev Argent Microbiol 1985;17(4):221-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 86213480 AU - Mailloux M TI - [Course on leptospirosis] LA - Fre MH - Animal MH - Antibiotics/therapeutic use MH - Bacterial Vaccines/administration & dosage MH - Dogs MH - Guinea Pigs MH - Hamsters MH - Human MH - Leptospira/growth & development/isolation & purification MH - *Leptospirosis/microbiology/therapy MH - Rabbits RN - 0 (Antibiotics) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 860606 DP - 1985 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 363-75 CY - ITALY IP - 3 VI - 21 JC - 5BP EM - 8608 PMID- 3834810 CU - 91 TT - Cours sur les leptospiroses. SO - Ann Ist Super Sanita 1985;21(3):363-75 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 86180937 AU - Everard CO AU - Fraser-Chanpong GM AU - James AC AU - Butcher LV TI - Serological studies on leptospirosis in livestock and chickens from Grenada and Trinidad. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/immunology MH - Chickens MH - Goats MH - Horse Diseases/immunology MH - Horses MH - Leptospirosis/immunology/*veterinary MH - Poultry Diseases/immunology MH - Sheep MH - Sheep Diseases/immunology MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/immunology MH - Trinidad and Tobago MH - West Indies RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 860507 DP - 1985 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 859-64 SB - M CY - ENGLAND IP - 6 VI - 79 JC - WBU AA - Author EM - 8607 AB - Sera from 1,206 livestock animals and chickens on Grenada and Trinidad were tested for leptospiral antibodies by the microscopic agglutination test. 376 of the sera were positive (25% of those tested on Grenada and 44% on Trinidad). The positive sera were obtained from 25% of 324 cattle, 35% of 130 pigs, 35% of 146 sheep, 25% of 44 goats and 11% of 175 chickens on Grenada; and 92% of 26 cattle, 53% of 122 pigs, 76% of 87 horses and donkeys and 11% of 144 chickens on Trinidad. Eight sera from ducks and geese on Trinidad were tested and found to be negative. The serogroups most commonly found to react with the sera of the Grenadian animals were Autumnalis, Icterohaemorrhagiae, Hebdomadis and the related serogroups Sejroe and Mini, and Pyrogenes; in the Trinidadian animals they were Icterohaemorrhagiae, Autumnalis, Hebdomadis and its related serogroups, and Panama. Strains of serogroup Pomona do not appear to have become established as livestock pathogens on the islands. PMID- 3832496 CU - 91 SO - Trans R Soc Trop Med Hyg 1985;79(6):859-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 86174411 AU - Kobayashi Y AU - Tamai T AU - Sada E TI - Serological analysis of serogroup icterohaemorrhagiae using monoclonal antibodies. LA - Eng MH - Antibodies, Monoclonal/*immunology MH - Antigens, Bacterial/immunology MH - Human MH - Leptospira interrogans/*classification/immunology MH - Weil's Disease/microbiology RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 860522 DP - 1985 IS - 0385-5600 TA - Microbiol Immunol PG - 1229-35 SB - M CY - JAPAN IP - 12 VI - 29 JC - MX7 AA - Author EM - 8607 AB - Eighteen serovars (19 strains) of serogroup Icterohaemorrhagiae were serologically analyzed using 18 monoclonal antibodies against serovar copenhageni Shiromizu, M20 and serovar icterohaemorrhagiae RGA strains. The reaction patterns of the serovars against these monoclonal antibodies were different. According to these results, we divided the serovars, except for serovar tonkini, into the following three subgroups: Subgroup 1 reacted to many monoclonal antibodies including serovars icterohaemorrhagiae, copenhageni, hualien, monymusk, mankarso, and budapest. Subgroup 2 fell between subgroups 1 and 3 including serovars dakota, naam, bogvere, birkini, smithi, ndambari, gem, ndahambukuje and mwogolo. Subgroup 3 reacted to only a few monoclonal antibodies: serovars weaveri and sarmin. Serovar tonkini did not react to any of the monoclonal antibodies used. There is a possibility that serovar tonkini does not belong to serogroup Icterohaemorrhagiae. Further studies on the serological reactions of each strain revealed that it was impossible to distinguish the RGA strain from the serovar hualien LT11-31 strain, indicating that they may be identical. It was also observed that serovar copenhageni and monymusk seemed to be closely related. Serovars birkini and smithi, and serovars ndambari and gem were alike in their serological reactivities. Among the 18 monoclonal antibodies, RGAMA-1 was a unique antibody which reacted only to serovar icterohaemorrhagiae and serovar hualien, indicating that it must be the serovar icterohaemorrhagiae specific antibody. On the other hand, SHIRMA-2, 5, 6 reacted to all the serovars except for serovars weaveri, sarmin, and tonkini. These antibodies exhibited a broad reaction spectrum. PMID- 3831722 CU - 91 SO - Microbiol Immunol 1985;29(12):1229-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85112102 AU - Szalka A AU - Telegdy L AU - Khoor A TI - [Malignant leptospirosis with fatal outcome] LA - Hun MH - Adult MH - Antibodies, Bacterial/immunology/isolation & purification MH - Case Report MH - English Abstract MH - Human MH - Kidney Glomerulus/immunology/pathology MH - Leptospira/immunology MH - Leptospirosis/immunology/*pathology MH - Male MH - Muscles/immunology/pathology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850228 DP - 1984 Dec 30 IS - 0030-6002 TA - Orv Hetil PG - 3243-5 CY - HUNGARY IP - 53 VI - 125 JC - OL8 EM - 8505 PMID- 6522046 CU - 91 TT - Halalos kimenetelu malignus leptospirosis. EA - A SO - Orv Hetil 1984 Dec 30;125(53):3243-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 85116895 AU - Hathaway SC AU - Todd JN AU - Headlam SA AU - Jeffrey M TI - Possible role of leptospires of the Pomona serogroup in sporadic bovine abortion in the south west of England. LA - Eng MH - Abortion, Veterinary/epidemiology/*microbiology MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology/*microbiology MH - Disease Outbreaks/*veterinary MH - England MH - Europe MH - Female MH - Leptospira/*classification/isolation & purification MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/*veterinary MH - Weil's Disease/epidemiology/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 850311 DP - 1984 Dec 15 IS - 0042-4900 TA - Vet Rec PG - 623-6 SB - M CY - ENGLAND IP - 24 VI - 115 JC - XBS AA - Author EM - 8505 AB - An investigation of a small outbreak of abortion in mixed-age cows in a dairy herd in Somerset produced circumstantial evidence that a leptospire belonging to the Pomona serogroup was the causative agent. Although the initial epidemic involved more than 30 per cent of the herd, agglutination titres did not persist in the majority of animals and bacteriological monitoring produced no evidence that this leptospire could establish endemic infection in dairy cattle. An isolate recovered from the kidney of a cow which aborted was found to be similar to mozdok, a serovar maintained by free-living species in continental Europe, and it is probable that free-living species also maintain the Pomona serogroup organisms that have been isolated in England. Clinical disease caused by infection of domestic stock with Pomona serogroup organisms other than pomona has not been recognised in other countries but this may be because of the presence of endemic infection with pomona, a serovar that causes a very similar clinical and serological response. PMID- 6523702 CU - 88 SO - Vet Rec 1984 Dec 15;115(24):623-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85073497 AU - Forwell MA AU - Redding PJ AU - Brodie MJ AU - Gentleman DD TI - Leptospirosis complicated by fatal intracerebral haemorrhage. LA - Eng MH - Adult MH - Brain/pathology MH - Case Report MH - Cerebral Hemorrhage/*etiology/pathology MH - Human MH - Male MH - Weil's Disease/*complications/pathology PT - JOURNAL ARTICLE DA - 850125 DP - 1984 Dec 8 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 1583 SB - A SB - M SB - X CY - ENGLAND IP - 6458 VI - 289 JC - B4X EM - 8504 PMID- 6439329 CU - 91 SO - Br Med J (Clin Res Ed) 1984 Dec 8;289(6458):1583 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85206714 AU - Shimizu MM TI - Environmental and biological determinants for the prevalence of leptospirosis among wild small mammal hosts, island of Hawaii. LA - Eng MH - Animal MH - Carnivora/*microbiology MH - Female MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Mice MH - Mongoose/*microbiology MH - Muridae/*microbiology MH - Rats PT - JOURNAL ARTICLE DA - 850724 DP - 1984 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 173-88 SB - M CY - TAIWAN IP - 2 VI - 11 JC - GTK AA - Author EM - 8509 AB - From October 1969 to January 31, 1973, an island-wide small mammal survey was conducted by the Hawaii State Department of Health in Hilo, Hawaii. A total of 2,982 rodents and mongooses from East and West Hawaii were cage-trapped and were examined by serological and cultural methods for evidence of leptospirosis. Of the 2,957 animals tested, 899 (30.4%) were culturally or serologically positive and 2058 (69.6%) were negative for evidence of leptospiral infection. Three leptospiral serotypes were isolated (L. icterohaemorrhagiae, L. ballum, and L. sejroe). The incidence among animal species was compared with earlier studies on this island. PMID- 6534904 CU - 90 SO - Int J Zoonoses 1984 Dec;11(2):173-88 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85206712 AU - Larsson CE AU - Santa Rosa CA AU - Hagiwara MK AU - Paim GV AU - Guerra JL TI - Prevalence of feline leptospirosis: serologic survey and attempts of isolation and demonstration of the agent. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Carrier State/veterinary MH - Cat Diseases/epidemiology/*microbiology MH - Cats MH - Female MH - Hemagglutination Tests MH - Leptospirosis/epidemiology/*veterinary MH - Male RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850724 DP - 1984 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 161-9 SB - M CY - TAIWAN IP - 2 VI - 11 JC - GTK AA - Author EM - 8509 AB - The occurrence of leptospiral infection in cats was determined through the detection of specific antibodies based on the results of microscopic agglutination test and the attempts of isolation and histological demonstration of leptospires from the kidneys of these animals. Of 172 serum samples examined by microscopic agglutination test, 22 (12.8%) were positive with titers greater than or equal to 100. The most frequent serovar was pomona. In relation to the sex, significant differences were not seen; however the age distribution showed that feline leptospirosis is more frequent in adult cats. The attempts for isolation and demonstration of L. interrogans from renal parenchyma by culture or Warthin Starry technics were unsuccessful. PMID- 6534902 CU - 91 SO - Int J Zoonoses 1984 Dec;11(2):161-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85170720 AU - Hartman EG TI - Epidemiological aspects of canine leptospirosis in the Netherlands. LA - Eng MH - Age Factors MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Specificity MH - Dog Diseases/*epidemiology/immunology MH - Dogs MH - Female MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Male MH - Netherlands MH - Seasons MH - Sex Factors MH - Zoonoses RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850510 DP - 1984 Dec IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 350-9 SB - M CY - GERMANY, WEST IP - 2-3 VI - 258 JC - Y55 AA - Author EM - 8507 AB - The epidemiology of canine leptospirosis has been examined in a limited study in the Netherlands from 1969 through 1982. Leptospira interrogans serotype icterohaemorrhagiae and canicola were found to be the only serotypes causing clinical leptospirosis. However, positive agglutination titres to the serotypes grippotyphosa, bratislava, poi and ballum have also been detected. The incidence of infection caused by serotype icterohaemorrhagiae was highest during summer and autumn. Infections with serotype canicola were more evenly distributed over the year with only a slight increase during summer and autumn. Infections caused by serotype canicola were significantly more prevalent in male dogs, whereas infections with serotype icterohaemorrhagiae were found both in males and females in almost equal numbers. The incidence of infections with serotype icterohaemorrhagiae was highest in immature dogs. Infections with serotype canicola were detected in young as well as older animals. In contrast to the situation in the past, infections with serotype icterohaemorrhagiae are now more common than those caused by serotype canicola, which have become rare. The highest incidence of infection was found in the western part of the country. The majority of infections was demonstrated in guard-dogs and sporting-dogs. Dogs proved to be of minor importance as a source of human infection in the Netherlands. PMID- 6532025 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Dec;258(2-3):350-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 85170711 AU - Tsuchimoto M AU - Niikura M AU - Ono E AU - Kida H AU - Yanagawa R TI - Leptospiral attachment to cultured cells. LA - Eng MH - Adhesiveness MH - Animal MH - Cattle MH - Dogs MH - Immunoglobulins, Fab/immunology MH - Kidney MH - Leptospira/*physiology/pathogenicity MH - Leptospira canicola/physiology/pathogenicity MH - Leptospira interrogans/physiology/pathogenicity MH - Species Specificity MH - Tissue Culture MH - Virulence RN - 0 (Immunoglobulins, Fab) PT - JOURNAL ARTICLE DA - 850510 DP - 1984 Dec IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 268-74 SB - M CY - GERMANY, WEST IP - 2-3 VI - 258 JC - Y55 AA - Author EM - 8507 AB - Each virulent strain of copenhageni, canicola and pomona of Leptospira interrogans attached effectively to MDCK cells and primary dog kidney cells, while the avirulent or less virulent line of the same strain and avirulent strains belonging to the same serovars and the avirulent reference strains of other serovars did not. Inhibition of the attachment of the virulent copenhageni to MDCK cells was found in the presence of the homologous immunoglobulin G Fab fragment. Strains of L. biflexa attached to the animal cells, but they differed from those of virulent L. interrogans in their capability to attach to glass. PMID- 6532022 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Dec;258(2-3):268-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 85079668 AU - Hodgin C AU - Schillhorn van Veen TW AU - Fayer R AU - Richter N TI - Leptospirosis and coccidial infection in a guanaco. LA - Eng MH - Animal MH - Animals, Zoo/microbiology/parasitology MH - Artiodactyla/*parasitology MH - Camelids, New World/*parasitology MH - Case Report MH - Coccidia/growth & development MH - Coccidiosis/complications/parasitology/*veterinary MH - Enteritis/veterinary MH - Female MH - Intestinal Diseases, Parasitic/veterinary MH - Jejunal Diseases/veterinary MH - Leptospira/ultrastructure MH - Leptospirosis/complications/microbiology/*veterinary MH - Nephritis, Interstitial/veterinary PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1442-4 SB - M CY - UNITED STATES IP - 11 VI - 185 JC - HAV EM - 8504 PMID- 6511616 CU - 90 SO - J Am Vet Med Assoc 1984 Dec 1;185(11):1442-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85056483 AU - Estavoyer JM AU - Stimmesse B AU - Ottignon Y AU - Cardot N AU - Boillot A AU - Dupont MJ TI - Serum lipids in patients with leptospirosis [letter] LA - Eng MH - Human MH - Leptospirosis/*blood MH - Lipids/*blood MH - Lipoproteins/blood RN - 0 (Lipoproteins) PT - LETTER DA - 850102 DP - 1984 Dec IS - 0022-1899 TA - J Infect Dis PG - 963-4 SB - A SB - M CY - UNITED STATES IP - 6 VI - 150 JC - IH3 EM - 8503 PMID- 6501936 CU - 91 SO - J Infect Dis 1984 Dec;150(6):963-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [7 medline neighbors] UI - 85054619 AU - Charon NW AU - Daughtry GR AU - McCuskey RS AU - Franz GN TI - Microcinematographic analysis of tethered Leptospira illini. LA - Eng MH - Cell Movement MH - Computers MH - Leptospira/*physiology MH - Motion Pictures MH - Rotation MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE ID - DEO4645 DA - 850118 DP - 1984 Dec IS - 0021-9193 TA - J Bacteriol PG - 1067-73 SB - M CY - UNITED STATES IP - 3 VI - 160 JC - HH3 AA - Author EM - 8503 AB - A model of Leptospira motility was recently proposed. One element of the model states that in translating cells the anterior spiral-shaped end gyrates counterclockwise and the posterior hook-shaped end gyrates clockwise. We tested these predictions by analyzing cells tethered to a glass surface. Leptospira illini was incubated with antibody-coated latex beads (Ab-beads). These beads adhered to the cells, and subsequently some cells became attached to either the slide or the cover glass via the Ab-beads. As previously reported, these cells rapidly moved back and forth across the surface of the beads. In addition, a general trend was observed: cells tethered to the cover glass rotated clockwise around the Ab-bead; cells tethered to the slide rotated counterclockwise around the Ab-bead. A computer-aided microcinematographic analysis of tethered cells indicated that the direction of rotation of cells around the Ab-bead was a function of both the surface of attachment and the shape of the cell ends. The results can best be explained by assuming that the gyrating ends interact with the glass surface to cause rotation around the Ab-beads. The analysis obtained indicates that the hook- and spiral-shaped ends rotate in the directions predicted by the model. In addition, the tethered cell assay permitted detection of rapid, coordinated reversals of the cell ends, e.g., cells rapidly switched from a hook-spiral configuration to a spiral-hook configuration. These results suggest the existance of a mechanism which coordinates the shape of the cell ends of L. illini. PMID- 6501226 SO - J Bacteriol 1984 Dec;160(3):1067-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85053504 AU - Wang B AU - Sullivan JA AU - Sullivan GW AU - Mandell GL TI - Role of specific antibody in interaction of leptospires with human monocytes and monocyte-derived macrophages. LA - Eng MH - Antibodies, Bacterial/immunology MH - Blood Bactericidal Activity MH - Human MH - Leptospira/*immunology MH - Macrophages/*immunology MH - Microscopy, Electron MH - Monocytes/*immunology MH - Neutrophils/immunology MH - Phagocytosis MH - Support, U.S. Gov't, P.H.S. RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE ID - AI09504/AI/NIAID DA - 841231 DP - 1984 Dec IS - 0019-9567 TA - Infect Immun PG - 809-13 SB - M SB - X CY - UNITED STATES IP - 3 VI - 46 JC - GO7 AA - Author EM - 8503 AB - It has previously been shown that human neutrophils ingest and kill nonpathogenic Leptospira biflexa in the absence of serum but that pathogenic Leptospira interrogans is not ingested by neutrophils even in the presence of normal serum. We extended this study by examining the interactions of human monocytes and monocyte-derived macrophages with pathogenic L. interrogans (serovar icterohaemorrhagiae) and evaluating the opsonizing effect of serotype-specific immune serum on the phagocytosis of pathogenic leptospires by monocytes and neutrophils. Leptospires were incubated with monocytes in pellets at 37 degrees C in 5% CO2. No ingestion or killing of pathogenic leptospires occurred when 10% normal serum was used. However, when the pathogenic leptospires were pretreated with serotype-specific immune serum, monocytes or neutrophils in pellets ingested 96% of the organisms and killed 94% of those ingested. Microscopic observations of the interaction confirmed that phagocytosis of the opsonized pathogenic leptospires by monocytes, monocyte-derived macrophages, and neutrophils had occurred. The opsonizing effect of specific antibody may play an important role in the mechanism of host defense against leptospirosis. PMID- 6500713 CU - 96 SO - Infect Immun 1984 Dec;46(3):809-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 85116855 AU - Treml F AU - Hejlicek K AU - Soukup M TI - [Incidence of antibodies against leptospira in the blood of breeding sows] LA - Cze MH - Animal MH - Antibodies, Bacterial/*analysis MH - Breeding MH - English Abstract MH - Female MH - Leptospira/*immunology MH - Swine/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850307 DP - 1984 Dec IS - 0375-8427 TA - Vet Med (Praha) PG - 713-8 SB - M CY - CZECHOSLOVAKIA IP - 12 VI - 29 JC - XBP AA - Author EM - 8505 AB - Within a year, 4438 blood sera of sows coming from 25 farms of the Strakonice district were subjected to serological examination by the reaction of microagglutination lysis (RMAL) with 12 strains of Leptospira. The reaction was positive in 3.22% of all the blood sera. Separate significant titres were demonstrated in the reaction with the Leptospira organisms of four serological groups, including Grippotyphosa, Icterohaemorrhagiae, Hebdomadis and Australis. The reactions with the Leptospira of the Canicola serological group were observed only individually as coagglutination with a simultaneous occurrence of antibodies to Leptospira of the Grippotyphosa serological group. The highest number of reactions 119 (75.8%) was demonstrated in titre 400. PMID- 6441335 CU - 91 TT - Vyskyt protilatek proti leptospiram v krevnim seru chovnych prasnic. EA - A SO - Vet Med (Praha) 1984 Dec;29(12):713-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85194960 TI - [Diagnosis of leptospirosis] LA - Ger MH - Agglutination Tests/methods MH - Bacteriological Techniques MH - Body Fluids/microbiology MH - Complement Fixation Tests/methods MH - Human MH - Leptospira/isolation & purification/pathogenicity MH - Leptospirosis/*diagnosis MH - Serodiagnosis/methods PT - JOURNAL ARTICLE DA - 850613 DP - 1984 Dec IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 480-91 SB - M CY - GERMANY, WEST IP - 4 VI - 258 JC - Y55 EM - 8508 PMID- 6398569 CU - 90 NI - A TT - Diagnostik bei Leptospirosen. SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Dec;258(4):480-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 85105434 AU - Fairbrother JM TI - Serological interrelationship of Leptospira serovar and genus-specific antigens by enzyme-linked immunosorbent assay. LA - Eng MH - Animal MH - Antigens, Bacterial/*immunology MH - Enzyme-Linked Immunosorbent Assay MH - Epitopes MH - Immunization MH - Leptospira/*immunology MH - Male MH - Rabbits MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 850306 DP - 1984 Dec IS - 0095-1137 TA - J Clin Microbiol PG - 1089-93 SB - M CY - UNITED STATES IP - 6 VI - 20 JC - HSH AA - Author EM - 8505 AB - The serological interrelationship of a sonicated antigen (POM-S) and an alkali-extracted "fraction 4" antigen (POM-F4) from Leptospira interrogans serovar pomona, and an ethanol-precipitated (PAT-E) and a formolized, sonicated antigen (PAT-F) from Leptospira biflexa serovar patoc were investigated. The serological responses of rabbits immunized with these antigens were examined by the enzyme-linked immunosorbent assay (ELISA), the microscopic agglutination test, and the 2- mercaptoethanol microscopic agglutination test. Antisera from these rabbits absorbed by the homologous or heterologous antigens were examined by the ELISA. The PAT-E and PAT-F antigens were genus specific and were serologically closely related but not identical. Similarly, the POM-F4 and POM-S antigens showed some serological relatedness. By the use of absorbed antisera, the serovar pomona-derived antigens were shown to be serologically related to the PAT-F but not to the PAT-E antigen in the ELISA. It is suggested that the use of several such antigens in the ELISA may reveal differences in the kinetics of the antibody response in animals infected by different leptospiral serovars. PMID- 6084016 CU - 95 SO - J Clin Microbiol 1984 Dec;20(6):1089-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85035998 AU - Adler B AU - Ballard S AU - Faine S TI - EIA test for leptospirosis [letter] LA - Eng MH - Human MH - *Immunoenzyme Techniques MH - Leptospirosis/*diagnosis MH - Support, Non-U.S. Gov't PT - LETTER DA - 841210 DP - 1984 Nov 10 IS - 0025-729X TA - Med J Aust PG - 685-6 SB - M SB - X CY - AUSTRALIA IP - 10 VI - 141 JC - M26 EM - 8502 PMID- 6387415 CU - 91 SO - Med J Aust 1984 Nov 10;141(10):685-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 85116612 AU - Griffiths IB AU - Gallego MI AU - De Leon LS TI - Levels of some reproductive diseases in the dairy cattle of Colombia. LA - Eng MH - Abortion, Veterinary/epidemiology MH - Animal MH - Brucellosis, Bovine/*epidemiology MH - Campylobacter fetus MH - Campylobacter Infections/epidemiology/*veterinary MH - Cattle MH - Cattle Diseases/*epidemiology MH - Colombia MH - Comparative Study MH - Dairying MH - Female MH - Male MH - Pregnancy MH - Support, Non-U.S. Gov't MH - Trichomonas Infections/epidemiology/*veterinary MH - Weil's Disease/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 850308 DP - 1984 Nov IS - 0049-4747 TA - Trop Anim Health Prod PG - 219-23 SB - M CY - SCOTLAND IP - 4 VI - 16 JC - WG2 AA - Author EM - 8505 AB - Of 4,144 serum samples collected from cows on 113 farms from eight areas of Colombia 3.3% had positive and 8.8% inconclusive titres to Brucella abortus, 21.7, 6.3, 1.6, 0.6 and 0.7% of cows had positive titres to Leptospira serovars hardjo, pomona, canicola, icterohaemorrhagiae and grippotyphosa respectively. Questionnaires completed on 110 farms revealed that 6, 2.5 and 4.6% of cows had had metritis, aborted or retained their placentas respectively in the previous 12 months. Trichomonas foetus and Campylobacter fetus were isolated from 13.7% and 15% of the bulls sampled on 103 farms. Six and two bulls had inconclusive and positive titres to Brucella abortus. Eight and 23 bulls had positive titres to pomona and hardjo. The results were discussed and remedies for control suggested. PMID- 6523582 CU - 88 SO - Trop Anim Health Prod 1984 Nov;16(4):219-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85254803 AU - Liang CX TI - [Serological response to leptospiral vaccine injected using different schedules] LA - Chi MH - Antibodies, Bacterial/*analysis MH - Bacterial Vaccines/*immunology MH - English Abstract MH - Human MH - *Immunization Schedule MH - Leptospira/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 850919 DP - 1984 Oct IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 287-90 CY - CHINA IP - 5 VI - 5 JC - CQG EM - 8511 PMID- 6536375 CU - 91 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1984 Oct;5(5):287-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 85117790 AU - Anan'ina IuV AU - Chernukha IuG TI - [Sensitivity of different morphological variants of Leptospira to the leptospirocidal activity of normal animal sera] LA - Rus MH - Animal MH - *Blood Bactericidal Activity MH - Cattle MH - Comparative Study MH - English Abstract MH - Leptospira/classification/cytology/*drug effects MH - Male MH - Microbial Sensitivity Tests MH - Serotyping MH - Sheep PT - JOURNAL ARTICLE DA - 850227 DP - 1984 Oct IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 72-3 SB - M CY - USSR IP - 10 JC - Y9O AA - Author EM - 8505 AB - The leptospirocidal activity of normal animal sera with respect to 23 Leptospira strains was experimentally studied in vitro. 91.3% of the strains under study proved to be sensitive to the lytic action of cattle serum and 86.9%, to sheep serum. The uncinate variants of the pathogenic strains showed resistance to the action of the above sera, and their nonuncinate analogs were subject to agglutination with subsequent lysis, similarly to saprophytes. PMID- 6524167 TT - Chuvstvitel'nost' razlichnykh morfologicheskikh variantov Leptospira k leptospirotsidnoi aktivnosti normal'nykh syvorotok zhivotnykh. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1984 Oct;(10):72-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [78 medline neighbors] UI - 85117741 AU - Mazzonelli J AU - Dorta de Mazzonelli G AU - Mailloux M TI - Evaluation of the leptospiral protein-free medium. LA - Eng MH - Comparative Study MH - *Culture Media MH - Leptospira interrogans/*growth & development/immunology MH - Polysorbates RN - 0 (Culture Media) RN - 0 (Polysorbates) PT - JOURNAL ARTICLE DA - 850308 DP - 1984 Oct IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 27-31 SB - M CY - GERMANY, WEST IP - 1 VI - 258 JC - Y55 AA - Author EM - 8505 AB - Bey and Johnson's leptospiral protein-free medium is evaluated and some modifications to it are introduced. Different serovars have shown good growth in this medium, but generally it is necessary to adapt it before obtaining success. When adapted, the serovars, subcultured serially, have a long term survival, with a good bacterial density. Some serovars, such as tarassovi and grippotyphosa exhibited irregular results. PMID- 6524154 CU - 92 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Oct;258(1):27-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85089930 AU - Jacques MC TI - [Icterohemorrhagic leptospirosis] LA - Fre MH - Case Report MH - Human MH - Kidney/pathology MH - Liver/pathology MH - Male MH - Middle Age MH - Weil's Disease/*diagnosis/pathology PT - JOURNAL ARTICLE DA - 850125 DP - 1984 Oct IS - 0035-3655 TA - Rev Med Suisse Romande PG - 841-5 CY - SWITZERLAND IP - 10 VI - 104 JC - SR5 EM - 8504 PMID- 6515231 TT - Leptospirose ictero-hemorragique. SO - Rev Med Suisse Romande 1984 Oct;104(10):841-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 85067344 AU - Hartman EG AU - van Houten M AU - Frik JF AU - van der Donk JA TI - Humoral immune response of dogs after vaccination against leptospirosis measured by an IgM- and IgG-specific ELISA. LA - Eng MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Comparative Study MH - Dog Diseases/prevention & control MH - Dogs MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - IgG/biosynthesis MH - IgM/biosynthesis MH - Leptospira interrogans/*immunology MH - Leptospirosis/*prevention & control/veterinary MH - Male MH - Vaccination RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850124 DP - 1984 Oct IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 245-54 SB - M CY - NETHERLANDS IP - 3-4 VI - 7 JC - XCB AA - Author EM - 8503 AB - An IgM- and IgG-specific ELISA was used to measure the antibody response stimulated in dogs by vaccination with a leptospiral bacterin containing chemically inactivated Leptospira interrogans serotype icterohaemorrhagiae and serotype canicola leptospires. All dogs produced anti-leptospiral IgM and IgG. The IgM production was of the primary response type after each vaccination (primary vaccination, booster vaccination and annual revaccination). A substantial anti- leptospiral IgG response could be demonstrated only after the first booster vaccination and the annual revaccination. Annual revaccination resulted in a higher and much longer persisting IgG response than did the first booster vaccination. A revision of the vaccination scheme is suggested. PMID- 6506449 CU - 91 SO - Vet Immunol Immunopathol 1984 Oct;7(3-4):245-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85061099 AU - Thiermann AB TI - Isolation of leptospires in diagnosis of leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/diagnosis/*microbiology MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Leptospira/immunology/*isolation & purification MH - Leptospirosis/diagnosis/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 841226 DP - 1984 Oct IS - 0362-8140 TA - Mod Vet Pract PG - 758-9 SB - M CY - UNITED STATES IP - 10 VI - 65 JC - NGO AA - Author EM - 8503 AB - Though the microscopic agglutination test is commonly used as an aid to diagnosis of leptospirosis, it lacks sensitivity, cannot differentiate vaccinal titers from those of infection, and cannot identify shedders. The ELISA is sensitive but also cannot differentiate titers of vaccination and infection. Leptospire isolation is essential for a final diagnosis. Tissue or fluid samples should be aseptically collected, if possible, and quickly shipped to the diagnostic laboratory in transport medium or on ice, but should not be frozen. Samples to be collected may include urine, milk, kidney, aqueous humor, and fallopian tube or uterine mucosa. PMID- 6504012 CU - 91 SO - Mod Vet Pract 1984 Oct;65(10):758-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85124837 AU - Nie DK AU - Wu SH AU - Shi MH AU - Lu ML AU - Jiang SX AU - Zhu GF AU - Wang HQ AU - Liu YM TI - [Studies on endotoxin of Leptospira: I. Extraction of lipopolysaccharides from Leptospira interrogans serovar Lai and analysis of their chemical and biological properties] LA - Chi MH - Animal MH - Comparative Study MH - English Abstract MH - Leptospira interrogans/*analysis MH - Lipopolysaccharides/*isolation & purification MH - Mice MH - Rabbits MH - Serotyping RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 850425 DP - 1984 Oct IS - 1000-503X TA - Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao PG - 321-5 CY - CHINA IP - 5 VI - 6 JC - CZS EM - 8506 PMID- 6241080 CU - 92 EA - A SO - Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao 1984 Oct;6(5):321-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85030976 AU - Marshall RB AU - Winter PJ AU - Yanagawa R TI - Restriction endonuclease DNA analysis of Leptospira interrogans serovars icterohaemorrhagiae and hebdomadis. LA - Eng MH - DNA Restriction Enzymes/*pharmacology MH - DNA, Bacterial/*analysis MH - Electrophoresis, Polyacrylamide Gel MH - Leptospira interrogans/*analysis/immunology MH - Molecular Weight MH - Mutation RN - EC 3.1.21 (DNA Restriction Enzymes) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 841206 DP - 1984 Oct IS - 0095-1137 TA - J Clin Microbiol PG - 808-10 SB - M CY - UNITED STATES IP - 4 VI - 20 JC - HSH AA - Author EM - 8502 AB - Antigenic variants of Leptospira interrogans serovars copenhageni and hebdomadis were examined by bacterial restriction endonuclease DNA analysis with EcoRI, XhoI, SalI, BstEII, and HindIII as the digesting enzymes. The antigenic variants were stable cloned strains which had been cultivated in media containing homologous immune serum. One of the strains examined has been reported elsewhere (R. Yanagawa and J. Takashima, Infect. Immun. 10:1439-1442) as having an antigenic makeup which more closely resembles serovar kremastos than the serovar hebdomadis parent. The closely antigenically related but naturally occurring serovars icterhaemorrhagiae strain RGA and copenhageni strain M20 were examined in parallel. No differences could be shown between the hebdomadis parent and any of its mutants. Serovars copenhageni and icterohaemorrhagiae produced patterns which differed in the high- molecular-weight bands only. The Shibaura parent strain did not differ from copenhageni M20, but the Shibaura M1 strain differed from the other mutants and from icterohaemorrhagiae RGA in its high-molecular- weight bands. PMID- 6092434 CU - 93 SO - J Clin Microbiol 1984 Oct;20(4):808-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85092516 AU - Markov IS AU - Tat'ianko NV AU - Vovk AD AU - Lenartovich LS AU - Vinogradova GN TI - [Phenomenon of transient HBs antigenemia in leptospirosis patients] LA - Rus MH - Adult MH - Case Report MH - Counterimmunoelectrophoresis MH - English Abstract MH - Epitopes/analysis MH - False Positive Reactions MH - Female MH - Hepatitis B Surface Antigens/*analysis MH - Human MH - Leptospirosis/diagnosis/*immunology MH - Male RN - 0 (Epitopes) RN - 0 (Hepatitis B Surface Antigens) PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Oct IS - 0049-6804 TA - Vrach Delo PG - 116-9 CY - USSR IP - 10 JC - XLS EM - 8504 PMID- 6083665 CU - 95 TT - Fenomen transitornoi HBs-antigenemii u bol'nykh leptospirozom. EA - A SO - Vrach Delo 1984 Oct;(10):116-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 85041878 AU - Hathaway SC AU - Little TW AU - Jones TW AU - Stevens H AU - Butland RW TI - Infection by leptospires of the Pomona serogroup in cattle and pigs in south west England. LA - Eng MH - Animal MH - Case Report MH - Cattle MH - Cattle Diseases/epidemiology/*microbiology MH - Disease Outbreaks/epidemiology/*veterinary MH - England MH - Female MH - Leptospira interrogans/*classification/isolation & purification MH - Pregnancy MH - Pregnancy Complications, Infectious/epidemiology/microbiology/veterinary MH - Retrospective Studies MH - Serotyping MH - Swine MH - Swine Diseases/epidemiology/*microbiology MH - Weil's Disease/epidemiology/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 841205 DP - 1984 Sep 8 IS - 0042-4900 TA - Vet Rec PG - 246-8 SB - M CY - ENGLAND IP - 10 VI - 115 JC - XBS AA - Author EM - 8502 AB - Leptospires belonging to the Pomona serogroup were isolated from calves involved in two outbreaks of acute haemolytic disease which were characterised by jaundice, haemoglobinuria and high death rates. Retrospective case studies in which serological evidence of Pomona serogroup infection was found are also presented. Serovar pomona is the leptospire of the Pomona serogroup most commonly incriminated in clinical disease in domestic species, but the organisms isolated in this study were antigenically different to pomona and may represent a new serovar. The limited information available on the epidemiology of sporadic infection with leptospires of the Pomona serogroup in domestic species in the south west of England supports the contention that a serovar other than pomona is involved. PMID- 6495570 CU - 88 SO - Vet Rec 1984 Sep 8;115(10):246-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 85068209 AU - Faine S AU - Adler B AU - Christopher W AU - Valentine R TI - Fatal congenital human leptospirosis. LA - Eng MH - Adult MH - Australia MH - Case Report MH - Female MH - Fetal Death/*etiology MH - Human MH - Leptospira interrogans/classification/*isolation & purification MH - Placenta/*microbiology MH - Pregnancy MH - Pregnancy Complications, Infectious/*diagnosis MH - Serotyping MH - Weil's Disease/complications/*diagnosis PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 548 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 EM - 8503 PMID- 6542285 CU - 85 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):548 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 85096653 AU - Ellis TM AU - Hustas L AU - Robertson GM AU - Mayberry C TI - Kidney disease of sheep, associated with infection by leptospires of the Sejroe serogroup. LA - Eng MH - Animal MH - Creatinine/blood MH - Kidney/pathology MH - Kidney Diseases/blood/microbiology/pathology/urine/*veterinary MH - Leptospirosis/blood/pathology/urine/*veterinary MH - Male MH - Sheep MH - Sheep Diseases/blood/*microbiology/pathology/urine MH - Zinc/poisoning RN - 60-27-5 (Creatinine) RN - 7440-66-6 (Zinc) PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Sep IS - 0005-0423 TA - Aust Vet J PG - 304-6 SB - M CY - AUSTRALIA IP - 9 VI - 61 JC - 9IE EM - 8504 PMID- 6517789 SO - Aust Vet J 1984 Sep;61(9):304-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 85068208 AU - Kemenes F TI - Leptospiral abortions of sows: new data. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Disease Susceptibility MH - Female MH - Fetal Diseases/etiology/veterinary MH - Gestational Age MH - Leptospira interrogans/*pathogenicity MH - Pregnancy MH - Species Specificity MH - Swine MH - Swine Diseases/*etiology MH - Weil's Disease/etiology/*veterinary PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 544-7 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 AA - Author EM - 8503 AB - In an immunization experiment, 460 sows at 7-60 days of gestation were inoculated with a rodent-adapted live strain of Leptospira interrogans serovar tarassovi at a large swine farm previously affected by this serovar. The inoculum consisted of a haemoculture prepared from the 52nd guinea-pig passage and the dose was 2 X 10(7) leptospires per sow. Over the period from the 48th to the 73rd day after inoculation 54 out of 283 sows having been inoculated at 32-60 days of gestation, aborted or delivered weak piglets. At the same time, 177 sows inoculated at days 7-32 of gestation farrowed normal litters. Altogether 18 underdeveloped piglets 2-5 weeks old derived from naturally infected litters were killed, but leptospires were not demonstrated or cultivated from their swollen and pale kidneys. It seems that L. interrogans serovar tarassovi is able to cause foetal damage in susceptible sows at one-two months of pregnancy and that previous adaptation of this serovar to rodents does not reduce its pathogenicity for porcine foetuses. PMID- 6506928 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):544-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85068207 AU - Mailloux M TI - Leptospirosis in New Caledonia (Melanesia). LA - Eng MH - Age Factors MH - Human MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/transmission MH - New Caledonia MH - Occupations MH - Seasons MH - Weil's Disease/diagnosis/epidemiology PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 540-1 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 EM - 8503 PMID- 6506927 CU - 88 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):540-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85068206 AU - Mailloux M AU - Mazzonelli JG AU - Raoult R TI - Leptospiroses in 1982 in France and French overseas departments. LA - Eng MH - France MH - French Guiana MH - Human MH - Indian Ocean Islands MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology/etiology/transmission MH - Species Specificity PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 535-8 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 EM - 8503 PMID- 6506926 CU - 88 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):535-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85068205 AU - Nicolescu M AU - Andreescu N TI - May human leptospirosis develop as a chronic infection? LA - Eng MH - Adult MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - Case Report MH - Chronic Disease MH - Complement Fixation Tests MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis MH - Male MH - Middle Age MH - Occupations MH - Romania RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 531-4 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 AA - Author EM - 8503 AB - In connection with some rather uncommon cases, the authors asked themselves whether leptospirosis may also develop as a chronic infection. To answer this question, we took into consideration four of the most representative investigated cases encountered during the last 22 years. In conclusion, it appears that in some circumstances, human leptospirosis could present itself as a chronic disease. PMID- 6506925 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):531-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85068202 AU - Mailloux M AU - Mazzonelli JG AU - Dufresne Y TI - Application of an immuno-enzyme technique to titration of antibodies in leptospirosis: ELISA (enzyme-linked immunosorbent assay). LA - Eng MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial/immunology MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Human MH - IgM/analysis MH - Leptospira/*immunology MH - Leptospirosis/diagnosis MH - Male RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 511-3 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 EM - 8503 PMID- 6506924 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):511-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85068201 AU - Hartman EG TI - An IgM- and IgG-specific enzyme-linked immunosorbent assay (ELISA) to detect anti-leptospiral immunoglobulins in dogs. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Dog Diseases/diagnosis MH - Dogs/*immunology MH - Enzyme-Linked Immunosorbent Assay MH - IgG/*analysis MH - IgM/*analysis MH - Immunization, Secondary/veterinary MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/veterinary MH - Vaccination/veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 508-10 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 EM - 8503 PMID- 6506923 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):508-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85068200 AU - Banfi E AU - Cinco M AU - Delia S AU - Castagnari L AU - Vullo V AU - Mastroianni CM AU - Contini C TI - New trends in the rapid serodiagnosis of leptospirosis. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/standards MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Immunoassay MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/epidemiology MH - Mass Screening MH - Serodiagnosis/*trends RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 503-7 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 AA - Author EM - 8503 AB - TR/Patoc slide test, ELISA and TIA (Thin-Layer Immunoassay) were evaluated for their use in a rapid serodiagnosis of human leptospirosis. The results obtained indicated that the TR/Patoc slide test is very sensitive and able to detect within a few minutes early antibodies against whichever serovar of leptospires, like the antigens of the Galton test. The value of the ELISA test in detecting antibodies at a low level is confirmed. The TIA assay, employed here for the first time for the diagnosis of leptospirosis, though sensitive seemed too long to perform and consequently it is not a test of choice for a rapid screening of sera. PMID- 6506922 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):503-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 85068199 AU - Weber A AU - Weber G AU - Krauss H TI - Evaluation of the slide agglutination test for detection of leptospiral antibodies in serum samples of slaughter pigs. LA - Eng MH - Abattoirs MH - Agglutination Tests/methods/*veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Germany, West MH - Leptospira interrogans/*immunology MH - Swine/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 498-500 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 AA - Author EM - 8503 AB - Serum samples of 259 randomly selected slaughter pigs were studied comparatively in the microscopic agglutination test (MAT) and the slide agglutination test (SAT) for the presence of leptospiral antibodies. 12 of 13 serum samples with MAT titres of 1:400+ + and higher were positive in the SAT. 27 of 46 sera with MAT titres in the borderline range (1:100+ + to 1:400+) showed a positive reaction in the SAT. 31 of 200 serum samples with MAT titres of 1:100+ and less reacted also positively in the SAT. Statistical evaluation of the results showed that the SAT is accurate if results are positive but less so if the results are negative (sensitivity 92.3%, specificity 76.4%). PMID- 6506921 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):498-500 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 85068198 AU - Schonberg A AU - Staak C AU - Kampe U TI - Use of formaldehyde-PBS for serum dilution in the microscopic agglutination test (MAT) for leptospirosis. LA - Eng MH - Agglutination Tests/*methods/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Formaldehyde MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/veterinary MH - Rabbits RN - 0 (Antibodies, Bacterial) RN - 50-00-0 (Formaldehyde) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 493-7 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 AA - Author EM - 8503 AB - Altogether, 431 sera (381 positive and 50 negative sera) were tested against different Leptospira serovars in the microscopic agglutination test (CMAT) using PBS with and without formaldehyde for comparative purposes. For the preparation of serum dilutions with formaldehyde-PBS, formaldehyde was added to PBS at a final concentration of 0.4%. When retested after storage, 234 from the 381 formerly positive sera gave positive, 68 doubtful and 79 negative results in the MAT. Out of the 234 sera with positive reaction in MAT, 212 (90.6%) showed positive reactions in the MAT with formaldehyde as well, 19 (8.1%) doubtful reactions and 3 (1.3%) became negative. All sera with negative reaction in the routine MAT were found to be negative in the MAT with formaldehyde as well. PMID- 6506920 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):493-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 84278652 AU - Berendsen HH AU - Rommes JH AU - Hylkema BS AU - Meinesz AF AU - Sluiter HJ TI - Adult respiratory failure with leptospirosis [letter] LA - Eng MH - Case Report MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Respiratory Distress Syndrome, Adult/*etiology PT - LETTER DA - 840912 DP - 1984 Sep IS - 0003-4819 TA - Ann Intern Med PG - 402 SB - A SB - M SB - X CY - UNITED STATES IP - 3 VI - 101 JC - 5A6 EM - 8411 PMID- 6465715 CU - 91 SO - Ann Intern Med 1984 Sep;101(3):402 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85067279 AU - Treml F AU - Sebek Z AU - Hejlicek K TI - [Territorial dissemination of antibodies against leptospirae at individual farms throughout a district, detected on the basis of serological testing of slaughter cattle and pigs] LA - Cze MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle/*immunology MH - Czechoslovakia MH - English Abstract MH - Leptospira/*immunology MH - Swine/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850104 DP - 1984 Sep IS - 0375-8427 TA - Vet Med (Praha) PG - 531-7 SB - M CY - CZECHOSLOVAKIA IP - 9 VI - 29 JC - XBP AA - Author EM - 8503 AB - The serological reaction of microagglutination-lysis (RMAL) was performed to examine 4995 head of slaughter cattle and 8211 slaughter pigs for the presence of antibodies to leptospirae. The animals came from 33 farms of the Strakonice district. Antibodies to leptospirae were found in slaughter cattle from 25 (75.75%) farms and in slaughter pigs from 24 (72.72%) farms. As suggested by the examination, the antibodies to leptospirae occur in animals throughout the territory of the district, irrespective of the nature of the landscape. The occurrence of the above-mentioned antibodies on farms occurred within the range from 0.52% to 8.33% in slaughter cattle and from 0.32% to 8.10% in slaughter pigs; only rarely did it exceed 9.0%. The most frequent reactions were those with the leptospirae of the L. grippotyphosa serovar. PMID- 6438868 CU - 91 TT - Plosne rozsireni protilatek proti leptospiram v jednotlivych zemedelskych zavodech okresu, zjistovane na zaklade serologickeho vysetreni jatecneho skotu a prasat. EA - A SO - Vet Med (Praha) 1984 Sep;29(9):531-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 90014343 AU - Matsiuk VM AU - Nazarova OG TI - [Leptospira hemosensitins obtained using a ballistic disintegration method] LA - Rus MH - Antigens, Bacterial/*isolation & purification MH - Chromatography, Gel MH - English Abstract MH - Hemagglutination Tests MH - Leptospira/*immunology MH - Spectrophotometry, Ultraviolet RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 891107 DP - 1984 Sep-Oct IS - 0201-8462 TA - Mikrobiol Zh PG - 80-5 CY - USSR IP - 5 VI - 46 JC - MY8 EM - 9001 PMID- 6400808 CU - 91 NP - X TT - Gemosensitiny leptospir, poluchennye s pomoshch'iu metoda ballisticheskoi dezintegratsii. EA - A SO - Mikrobiol Zh 1984 Sep-Oct;46(5):80-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 85078619 AU - Wilske B AU - Schierz G AU - Preac-Mursic V AU - Weber K AU - Pfister HW AU - Einhaupl K TI - Serological diagnosis of erythema migrans disease and related disorders. LA - Eng MH - Acrodermatitis/diagnosis/immunology MH - Adult MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Cross Reactions MH - Erythema/*diagnosis/immunology MH - Fluorescent Antibody Technique MH - Human MH - IgG/analysis MH - IgM/analysis MH - Leptospira/immunology MH - Lymphoma, Non-Hodgkin's/diagnosis/immunology MH - Meningitis/diagnosis/immunology MH - Polyradiculitis/diagnosis/immunology MH - Skin Neoplasms/diagnosis/immunology MH - Spirochaetales/*immunology MH - Spirochaetales Infections/*diagnosis/immunology MH - Treponema/immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850205 DP - 1984 Sep-Oct IS - 0300-8126 TA - Infection PG - 331-7 SB - M CY - GERMANY, WEST IP - 5 VI - 12 JC - GO8 AA - Author EM - 8504 AB - An indirect immunofluorescence technique for the determination of antibodies against ixodid tick spirochetes is described. Differences in the reactivity between Ixodes ricinus spirochete and Ixodes dammini spirochete antigens were not observed. Cross-reacting antibodies against Treponema pallidum and Treponema phagedenis can be eliminated by quantitative absorption with T. phagedenis. Cross-reactions with leptospira were not observed by immunofluorescence. In the IgM test, false negative reactions caused by high-titered specific IgG antibodies or false positive reactions caused by rheumatoid factor occur. This can be avoided by testing the IgM fraction (19S-IgM-test) or using sera previously treated with anti-IgG serum. Significantly elevated antibody titers against ixodid tick spirochetes were observed in 45% of 44 cases with erythema migrans disease, in 72% of 29 cases of lymphocytic meningoradiculitis, in all of nine patients with acrodermatitis chronica atrophicans and in all of four investigated patients with lymphocytoma (lymphadenosis benigna cutis). PMID- 6392104 CU - 91 SO - Infection 1984 Sep-Oct;12(5):331-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 85068204 AU - Hein B AU - Freudenstein H TI - Immunohistochemical investigations of leptospira-infected golden hamsters in potency tests. LA - Eng MH - Animal MH - Antigens, Bacterial/analysis MH - Bacterial Vaccines/*immunology MH - Comparative Study MH - Hamsters MH - Immunoenzyme Techniques MH - Kidney/immunology/microbiology MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/microbiology/*prevention & control MH - Liver/immunology/microbiology MH - Mesocricetus MH - Septicemia/microbiology MH - Spleen/immunology/microbiology RN - 0 (Antigens, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 521-5 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 AA - Author EM - 8503 AB - Golden hamsters taken from routine potency testing of leptospirosis vaccines were investigated for leptospirae after a challenge infection. Kidneys, livers, and spleens were examined immunohistochemically by the unlabelled antibody enzyme (PAP) method, and samples of these organs were additionally cultured for the evidence of living leptospirae. In non-vaccinated animals the recultivation method indicated leptospirae during the bacteraemic phase, beginning immediately after infection. Both methods resulted in positive reactions after organ manifestations. Intravascular evidence of leptospirae in the kidneys could be seen first on day 3 after infection. On day 7, there was intracellular and intratubular evidence as well, combined with tubulo-interstitial alterations. In vaccinated animals the bacteraemia after infection was reduced. Organ manifestations were seen rarely; there were less severe or no pathohistological alterations. PMID- 6391038 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):521-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85068196 AU - Gsell O TI - The history of leptospirosis: 100 years. LA - Eng MH - Animal MH - Antigens, Bacterial/analysis MH - Disease Outbreaks MH - History of Medicine, 19th Cent. MH - History of Medicine, 20th Cent. MH - Human MH - Leptospira/classification/immunology/pathogenicity MH - Leptospirosis/*history/microbiology/veterinary MH - Species Specificity RN - 0 (Antigens, Bacterial) PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE PT - REVIEW DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 473-8 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 EM - 8503 RF - 16 PMID- 6391037 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):473-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 85068203 AU - Bazovska S AU - Kmety E AU - Rak J TI - Differentiation of pathogenic and saprophytic leptospira strains. LA - Eng MH - Animal MH - Azaguanine MH - Comparative Study MH - Culture Media MH - Erythrocytes/immunology MH - Hemolysis MH - Leptospira/*classification/growth & development/pathogenicity MH - Protein Hydrolysates MH - Rats/immunology MH - Sheep/immunology MH - Temperature RN - 0 (Culture Media) RN - 0 (Protein Hydrolysates) RN - 134-58-7 (Azaguanine) RN - 65072-00-6 (casein hydrolysate) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 517-20 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 AA - Author EM - 8503 AB - Comparative studies of 249 pathogenic and 80 saprophytic leptospira strains, including 2 strains of the illini type, using the 8-azaguanine test, growth at 13 degrees C and growth on trypticase soy broth revealed their good differentiating potency if the recommended conditions were carefully observed. The same results were obtained by a simple hemolytic test using sheep and rat blood cells, having the advantage of providing results within 24 h. This test is suggested to replace the 8-azaguanine and the growth test at 13 degrees C. In these investigations, the first European strain of the illini type was recognized. PMID- 6239469 CU - 95 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):517-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 85068197 AU - Palmer M AU - Waitkins SA AU - Zochowski W TI - Survival of leptospires in commercial blood culture systems. LA - Eng MH - Blood/*microbiology MH - Blood Specimen Collection/methods MH - Culture Media MH - Human MH - Leptospira interrogans/*isolation & purification MH - Polyanetholesulfonate MH - Species Specificity MH - Time Factors RN - 0 (Culture Media) RN - 55963-78-5 (Polyanetholesulfonate) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 Sep IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 480-7 SB - M CY - GERMANY, WEST IP - 4 VI - 257 JC - Y55 AA - Author EM - 8503 AB - Laboratory diagnosis of leptospirosis depends on the serological findings and, if possible, the isolation of the organisms. During the period 1981-1982 there were 40 blood cultures submitted from serologically positive patients and a successful isolation rate of only 12% was attained. Correct media, method of collection of suspect blood and laboratory technique all contribute to the successful isolation of the organism. Because of the low isolation rate an investigation was undertaken of various blood culturing systems used in Great Britain. Results obtained showed that certain blood culture media were able to maintain the organism better and therefore increase the isolation rates of leptospira. Factors affecting the isolation rate are presented. PMID- 6095561 CU - 93 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Sep;257(4):480-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 84281587 TI - Leptospirosis in cattle and man [letter] LA - Eng MH - *Dairying MH - Human MH - Male MH - Meningitis/etiology MH - Occupational Diseases/*etiology MH - Weil's Disease/*transmission PT - LETTER DA - 840926 DP - 1984 Aug 11 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 380-1 SB - A SB - M SB - X CY - ENGLAND IP - 6441 VI - 289 JC - B4X EM - 8412 PMID- 6432107 CU - 91 NI - A SO - Br Med J (Clin Res Ed) 1984 Aug 11;289(6441):380-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85192011 AU - Riedemann S AU - Kother L AU - Zamora J TI - [Human leptospirosis due to the copenhageni serotype] LA - Spa MH - Adult MH - Antibodies, Bacterial/analysis MH - English Abstract MH - Human MH - *Leptospira/immunology MH - Leptospirosis/*diagnosis MH - Male MH - Serotyping RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850612 DP - 1984 Aug IS - 0034-9887 TA - Rev Med Chil PG - 809-11 CY - CHILE IP - 8 VI - 112 JC - SHD EM - 8508 PMID- 6533721 CU - 91 TT - Leptospirosis humana por serotipo Copenhageni. EA - A SO - Rev Med Chil 1984 Aug;112(8):809-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85192010 AU - Thompson L AU - Chesta J AU - Yenes A AU - Gonzalez P TI - [Weil's syndrome due to Leptospira interrogans of the ballum serotype] LA - Spa MH - Adult MH - Case Report MH - English Abstract MH - Female MH - Human MH - *Leptospira interrogans/isolation & purification MH - Male MH - Serotyping MH - Weil's Disease/diagnosis/*microbiology PT - JOURNAL ARTICLE DA - 850612 DP - 1984 Aug IS - 0034-9887 TA - Rev Med Chil PG - 806-8 CY - CHILE IP - 8 VI - 112 JC - SHD EM - 8508 PMID- 6533720 TT - Sindrome de Weil por Leptospira interrogans serogrupo ballum. EA - A SO - Rev Med Chil 1984 Aug;112(8):806-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 85074423 AU - Bao XH TI - [The effect of leptospiral outer envelope vaccine. IV. A study among a small population] LA - Chi MH - Adolescence MH - Adult MH - Antibodies, Bacterial/analysis MH - Bacterial Outer Membrane Proteins/*immunology MH - Bacterial Vaccines/*immunology MH - English Abstract MH - Human MH - Immunization MH - Leptospira/*immunology MH - Middle Age RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Outer Membrane Proteins) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 850219 DP - 1984 Aug IS - 0254-6450 TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 212-5 CY - CHINA IP - 4 VI - 5 JC - CQG EM - 8504 PMID- 6509528 CU - 91 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1984 Aug;5(4):212-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 85030823 AU - Hyde FW AU - Johnson RC TI - Genetic relationship of lyme disease spirochetes to Borrelia, Treponema, and Leptospira spp. LA - Eng MH - Animal MH - Base Composition MH - Borrelia/classification/*genetics MH - Cerebrospinal Fluid/microbiology MH - Comparative Study MH - Cytosine/analysis MH - *DNA, Bacterial/analysis MH - Guanine/analysis MH - Human MH - Leptospira/classification/*genetics MH - Lyme Disease/*microbiology MH - Nucleic Acid Hybridization MH - Plasmids MH - Spirochaetaceae/classification/*genetics MH - Ticks/microbiology MH - Treponema/classification/*genetics RN - 0 (DNA, Bacterial) RN - 0 (Plasmids) RN - 71-30-7 (Cytosine) RN - 73-40-5 (Guanine) PT - JOURNAL ARTICLE DA - 841213 DP - 1984 Aug IS - 0095-1137 TA - J Clin Microbiol PG - 151-4 SB - M CY - UNITED STATES IP - 2 VI - 20 JC - HSH AA - Author EM - 8502 AB - Genetic studies were performed on the following spirochetes: three Lyme disease spirochetes isolated from Ixodes ticks and from human spinal fluid; three species of North American borreliae; four species of Treponema; and two species of Leptospira. The mol% G+C values for Lyme disease spirochetes were 27.3 to 30.5%, similar to values of 28.0 to 30.5% for Borrelia species but different from the values of Leptospira or Treponema species which ranged from 35.3 to 53%. Lyme disease spirochetes represent a new species of Borrelia, with DNA homologies of 31 to 59% with the three North American strains of Borrelia studied. These studies also showed that Lyme disease spirochetes from three sources constituted a single species, with DNA homologies ranging from 76 to 100%. A high degree of relatedness was also seen between the three North American borreliae, with homology varying from 77 to 95%, indicating that these spirochetes represent a single species. Lyme disease spirochetes and Borrelia species exhibited almost no homology with Leptospira and Treponema species (0 to 2%). Plasmids were detected in the three Lyme disease spirochetes and in the three North American borreliae. PMID- 6490811 CU - 92 SO - J Clin Microbiol 1984 Aug;20(2):151-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85019021 AU - Riedemann S AU - Zamora J AU - Dumont C TI - [Experimental leptospiral vaccines. Serological findings in rabbits] LA - Spa MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Bacterial Vaccines/*immunology MH - Comparative Study MH - English Abstract MH - Hemagglutination Tests MH - Leptospira/*immunology MH - Rabbits RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 841114 DP - 1984 Aug IS - 0721-1856 TA - Zentralbl Veterinarmed [B] PG - 487-92 CY - GERMANY, WEST IP - 7 VI - 31 JC - Y72 EM - 8501 PMID- 6485648 CU - 91 TT - Bacterina experimental antileptospira. Respuesta serologica en conejos. EA - A SO - Zentralbl Veterinarmed [B] 1984 Aug;31(7):487-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 85018217 AU - Hartman EG AU - van Houten M AU - van der Donk JA AU - Frik JF TI - Determination of specific anti-leptospiral immunoglobulins M and G in sera of experimentally infected dogs by solid-phase enzyme-linked immunosorbent assay. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Dog Diseases/*immunology MH - Dogs MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - IgG/analysis MH - IgM/analysis MH - Leptospira canicola/*immunology MH - Leptospirosis/immunology/*veterinary MH - Male MH - Time Factors RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 841120 DP - 1984 Aug IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 43-51 SB - M CY - NETHERLANDS IP - 1 VI - 7 JC - XCB AA - Author EM - 8501 AB - The development and evaluation of an enzyme-linked immunosorbent assay (ELISA) to detect specific anti-leptospiral IgM and IgG in sera of dogs experimentally infected with Leptospira interrogans serotype canicola are reported. In all dogs specific anti-leptospiral IgM was detected from the second half of the first week after infection, the maximum being attained during the second week. Subsequently the IgM titre gradually decreased. Specific anti-leptospiral IgG was detected later and increased gradually to reach almost the same level as the IgM titre after two to three months. During the initial stage of the infection, when the microscopic agglutination titre was still negative or very low, a high IgM titre was accompanied by a negative or very low IgG titre in every case. After the initial stage a substantial IgG titre was also detectable. It is suggested that the test is suitable for serodiagnostic purposes, particularly for the diagnosis of a current infection in an individual. PMID- 6485247 CU - 91 SO - Vet Immunol Immunopathol 1984 Aug;7(1):43-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 85018216 AU - Hartman EG AU - van Houten M AU - van der Donk JA AU - Frik JF TI - Serodiagnosis of canine leptospirosis by solid-phase enzyme-linked immunosorbent assay. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/immunology MH - Comparative Study MH - Cross Reactions MH - Dog Diseases/*diagnosis MH - Dogs MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Leptospira canicola/immunology MH - Leptospirosis/diagnosis/*veterinary MH - Male RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 841120 DP - 1984 Aug IS - 0165-2427 TA - Vet Immunol Immunopathol PG - 33-42 SB - M CY - NETHERLANDS IP - 1 VI - 7 JC - XCB AA - Author EM - 8501 AB - An enzyme-linked immunosorbent assay (ELISA) to detect antibodies to Leptospira interrogans serotype canicola in dogs was developed and evaluated. Comparison of the ELISA with the microscopic agglutination test (MAT) showed that, during the first two weeks after an experimental infection with serotype canicola, the ELISA detected antibody at higher dilutions than the MAT. After the second week post- infection both tests detected antibody at almost equal titres (r = 0.89). The outer envelope (OE) antigen of serotypes icterohaemorrhagiae, copenhageni and canicola was fairly serotype- specific, whereas the pellet (P) antigen showed more cross-reactivity. Both OE and P antigen of Leptospira biflexa strain Patoc I could be used as cross-reacting antigen in the ELISA. Compared to the MAT, the ELISA has some technical advantages. It is suggested that the ELISA would be useful as a screening test. PMID- 6485246 CU - 91 SO - Vet Immunol Immunopathol 1984 Aug;7(1):33-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85006225 AU - Colgan M AU - Eivers B Jr AU - Egan J TI - An unrecognised zoonosis?: Leptospirosis hardjo in man in the Republic of Ireland. LA - Eng MH - Adult MH - Animal MH - *Animal Husbandry MH - Case Report MH - Cattle MH - Cattle Diseases/*transmission MH - Human MH - Ireland MH - Leptospirosis/*diagnosis/transmission/veterinary MH - Male MH - Occupational Diseases/*diagnosis MH - Zoonoses/*transmission PT - JOURNAL ARTICLE DA - 841101 DP - 1984 Aug IS - 0021-129X TA - Ir Med J PG - 238-40 CY - IRELAND IP - 8 VI - 77 JC - GXD EM - 8501 PMID- 6480324 SO - Ir Med J 1984 Aug;77(8):238-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 84279578 AU - Dreyer RF AU - Hopen G AU - Gass JD AU - Smith JL TI - Leber's idiopathic stellate neuroretinitis. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Macula Lutea MH - Male MH - Middle Age MH - Optic Neuritis/*diagnosis MH - Papilledema/diagnosis MH - Retinitis/*diagnosis MH - Retrospective Studies MH - Support, Non-U.S. Gov't MH - Syndrome PT - JOURNAL ARTICLE DA - 840829 DP - 1984 Aug IS - 0003-9950 TA - Arch Ophthalmol PG - 1140-5 SB - A SB - M CY - UNITED STATES IP - 8 VI - 102 JC - 830 AA - Author EM - 8411 AB - Twenty-nine eyes of 27 patients demonstrated the typical features of neuroretinitis with a mascular star. Historical and fluorescein angiographic features of this condition implicate a bloodborne infectious agent. It is likely that multiple agents can produce this condition, including the agent of cat-scratch fever and leptospirosis. A small subgroup may exist in whom this condition resembles anterior ischemic optic neuropathy and has a less favorable clinical course than is usual. There is evidence that this condition is not related to demyelinating disease. It is emphasized that this condition is not a maculopathy since vascular leakage in the optic nerve causes the star. Therefore, we suggest that this condition be renamed Leber's idiopathic stellate neuroretinitis. PMID- 6466174 CU - 90 SO - Arch Ophthalmol 1984 Aug;102(8):1140-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [48 medline neighbors] UI - 85002662 AU - Baxter DN AU - Leck I TI - The deleterious effects of dogs on human health: 2. Canine zoonoses. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Bites and Stings/complications MH - Campylobacter Infections/transmission MH - Cats MH - Cestode Infections/transmission MH - Child MH - Child, Preschool MH - Disease Reservoirs MH - Dog Diseases/*transmission MH - Dogs MH - Enteritis/transmission MH - Great Britain MH - Human MH - Infant MH - Leptospirosis/transmission MH - Mite Infestations/transmission MH - Pasteurella Infections/transmission MH - Salmonella Infections/transmission MH - Tinea/transmission MH - Toxocariasis/transmission MH - Wound Infection/etiology MH - Yersinia Infections/transmission MH - Zoonoses PT - JOURNAL ARTICLE PT - REVIEW DA - 841121 DP - 1984 Aug IS - 0142-2456 TA - Community Med PG - 185-97 CY - ENGLAND IP - 3 VI - 6 JC - DNI EM - 8501 RF - 73 PMID- 6383701 CU - 90 SO - Community Med 1984 Aug;6(3):185-97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 84267774 AU - Vinh T AU - Faine S AU - Adler B TI - Adhesion of leptospires to mouse fibroblasts (L929) and its enhancement by specific antibody. LA - Eng MH - Adhesiveness MH - Animal MH - Antibodies, Bacterial/*immunology MH - L Cells/microbiology/pathology/ultrastructure MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Mice MH - Microscopy/methods MH - Microscopy, Electron MH - Microscopy, Electron, Scanning MH - Microscopy, Phase-Contrast MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840907 DP - 1984 Aug IS - 0022-2615 TA - J Med Microbiol PG - 73-85 SB - M CY - ENGLAND IP - 1 VI - 18 JC - J2N AA - Author EM - 8411 AB - The adhesion of leptospires (Leptospira interrogans serovar. copenhageni L45) to mouse L-cells was studied by microscopic observations. Within 3 h of infection of monolayers many leptospires adhered to 95-100% of the cells, and intracellular leptospires were demonstrated by electron microscopy. No specific site of attachment on the cells or the leptospires was observed. Avirulent or dead leptospires adhered poorly but attachment of the saprophytic leptospire L. biflexa serovar. patoc occurred on cell and glass surfaces. After adhesion, microvilli on the cell surfaces disappeared within 6 h of infection and cell damage was observed after 12 h. The adhesion was greatly enhanced by the presence of specific antiserum at a subagglutinating concentration. No direct penetration by leptospires of the host cells was observed with transmission and scanning electron microscopy. It appears that (1) adhesion of leptospires to L-cells precedes cell damage, and (2) leptospires may enter cells either through damaged membranes, or by a phagocytosis-like mechanism. PMID- 6379182 CU - 91 SO - J Med Microbiol 1984 Aug;18(1):73-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [31 medline neighbors] UI - 85203639 AU - Gove S AU - Slutkin G TI - Infectious diseases of travelers and immigrants. LA - Eng MH - Bacterial Infections/*diagnosis/therapy/transmission MH - Biliary Tract Diseases/etiology MH - Dengue/*diagnosis/drug therapy/transmission MH - Diagnosis, Differential MH - Diarrhea/microbiology/therapy MH - Dysentery/microbiology/therapy MH - Emergencies MH - Fever/etiology MH - Gastrointestinal Diseases/etiology MH - Gastrointestinal Hemorrhage/etiology MH - Human MH - Liver Diseases/etiology MH - Lung Diseases/etiology MH - Malaria/*diagnosis/drug therapy/transmission MH - Peritonitis/etiology MH - Rickettsia Infections/*diagnosis/transmission MH - Spirochaetales Infections/diagnosis MH - Time Factors MH - *Transients and Migrants MH - Typhoid/diagnosis/drug therapy PT - JOURNAL ARTICLE DA - 850626 DP - 1984 Aug IS - 0733-8627 TA - Emerg Med Clin North Am PG - 587-622 SB - M CY - UNITED STATES IP - 3 VI - 2 JC - EGD AA - Author EM - 8509 AB - Many tropical and other unusual infections can occur in travelers or among foreign-born persons who have emigrated to the United States. The approach to the differential diagnosis includes considering the patient's geographic history, dates of travel, and clinical presentation, along with the geographic distribution and possible incubation periods of suspected pathogens. Important considerations include malaria, typhoid fever, rickettsial disease, dengue, brucellosis, tuberculosis, and leptospirosis. Traveler's diarrhea and dysentery are also common. PMID- 6335988 CU - 90 SO - Emerg Med Clin North Am 1984 Aug;2(3):587-622 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85072599 AU - Cinco M TI - [Activity in the field of leptospirosis at the University of Trieste] LA - Ita MH - English Abstract MH - Human MH - Italy MH - Leptospira/*classification MH - Leptospirosis/*diagnosis MH - Research MH - Serodiagnosis MH - Serotyping MH - *Universities PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Jul 31 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 267-8 SB - M CY - ITALY IP - 3 VI - 63 JC - AKG AA - Author EM - 8504 AB - The activity of Leptospira Laboratory in our Institute is briefly explained. The laboratory acts as International Reference for Leptospira typing, for microbiological diagnosis of leptospirosis and for basic research on pathogenesis and new trends in the serodiagnosis. PMID- 6508951 TT - Attivita svolta nel campo delle leptospire presso l'Istituto di Microbiologia dell'Universita di Trieste. EA - A SO - Boll Ist Sieroter Milan 1984 Jul 31;63(3):267-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 85072598 AU - Bianchi L TI - [The Pavia Center for the study and diagnosis of leptospirosis] LA - Ita MH - Animal MH - Animal Diseases/epidemiology MH - Diagnosis, Differential MH - Disease Reservoirs MH - English Abstract MH - Human MH - Italy MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis/epidemiology/veterinary MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Jul 31 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 262-6 SB - M CY - ITALY IP - 3 VI - 63 JC - AKG AA - Author EM - 8504 AB - According to his deep experience in this field, the Author greatly appreciates the program agreed during this congress. He thinks that Leptospirosis is a still widely diffused zoonosis, for which accurate diagnostic work-up is requested, coupled to an adequate epidemiologic study. Among his own contributions to this argument, the A. remarks the studies on the experimental infection of the guineapig with L. icterohaemorrhagiae, providing evidence that jaundice and lethal course of the illness are due to the Leptospira and not, as it was currently supposed, to an overcoming Staphylococcal septicemia. Furthermore the A. observed a striking epidemic by L. pomona affecting 90 out of 120 rice-workers in the neighbourhood of Pavia. This Leptospira, previously unreported in Europe, was found to be carried by Norvegian rats captured in that country. These data were in contrast with the more frequent incidence, in this work environment, of L. bataviae, carried by Micromis minutus sorcinus. Following the amount of observations and researches in this field "Center for study and diagnosis of Leptospirosis" was founded in 1954, and is still working in Pavia. The necessity of isolation of the infective agent, in addition to the simple serologic study, was claimed by the observation of five cases of meningitis in young pigherds, in which L. canicola (instead of the more common L. pomona) was demonstrated and ielded from the CSF of a patient. In the field of veterinary medicine, the A. demonstrated the L. australis A as responsible of some cases of miscarriages in openair breeded cattle. In those cases the hedgehog (Erinaceus europeus) was the natural carrier.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 6508950 CU - 88 TT - Il Centro di Pavia per lo studio e la diagnosi delle leptospirosi. EA - A SO - Boll Ist Sieroter Milan 1984 Jul 31;63(3):262-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85072597 AU - Gelosa L AU - Manera A TI - [Diagnostic research on leptospirosis in the Milanese territory] LA - Ita MH - Antibodies, Bacterial/analysis MH - English Abstract MH - Human MH - Italy MH - Leptospira/classification/isolation & purification MH - Leptospirosis/*diagnosis/epidemiology/microbiology MH - Serotyping MH - Water Microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Jul 31 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 254-61 SB - M CY - ITALY IP - 3 VI - 63 JC - AKG AA - Author EM - 8504 AB - 168 serum specimens have been tested for Leptospirosis in the years from 1980 to 1983. The identification procedure was a macroscopic plate agglutination screening test with formalin fied antigens and a confirmatory microscopic agglutination-lysis test of live antigens of actively growing cultures of different pathogenic serotypes propagated in a fluid medium. 34 serum specimens (23.8%) relevant to 18 cases were positive. L. icterohaemorrhagiae was positive in 12 cases (63.1%), L. pomona in 2 cases (10.5%), L. canicola in 1 case (5.3%), 1 case was positive for both L. grippotyphosa and L. bataviae and 1 case was positive for L. poi and L. sejroe. During the summer-fall of 1981 40 specimens of surface water from 4 pre-alpin lakes of the Provincia of Como were tested for Leptospiras with the cultural and biological examinations, following the detection of several leptospirosis cases on the relevant area. All water specimens gave negative results. PMID- 6508949 CU - 91 TT - Indagini diagnostiche sulle leptospirosi nel territorio Milanese. EA - A SO - Boll Ist Sieroter Milan 1984 Jul 31;63(3):254-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85072596 AU - Stella D AU - Bonomi U AU - Fraizzoli G AU - Tonolli E TI - [Diagnosis and surveillance of leptospirosis in the Venetia Region] LA - Ita MH - English Abstract MH - Human MH - Italy MH - Leptospira/classification/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/microbiology MH - Population Surveillance MH - Serotyping PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Jul 31 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 249-53 SB - M CY - ITALY IP - 3 VI - 63 JC - AKG AA - Author EM - 8504 AB - The Microbiological Laboratory of Verona Hospital is the leptospirosis reference Centre since 1980. It uses routinely the lysis/agglutination test with leptospires strains in order to confirm the clinical diagnosis and to define the typing of strains. Although this Centre is not yet officially recognized, it is in fact, at the service of the Veneto region and greater part of the Trentino Alto Adige. It examines 600 samples a year (about 3000 determinations) from these two regions, therefore it can construct a biregional epidemiology although the data is neither referred to superior Committees nor, perhaps, utilized in the requesting territory. The aspects of this service to be improved are the incompleteness of data with samples and their not perfect condition on arrival for testing. The most interesting point is that the epidemiology in the Veneto region has not changed since 1980: the prevailing leptospira is the icterohaemorrhagiae and then the canicola and pomona. PMID- 6508948 CU - 88 TT - Diagnostica e sorveglianza delle leptospirosi nella Regione Veneto. EA - A SO - Boll Ist Sieroter Milan 1984 Jul 31;63(3):249-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 85072595 AU - Castelletto M AU - Rigoli E TI - [Identification of proposed laboratories for leptospirosis surveillance at the regional and multiregional levels] LA - Ita MH - English Abstract MH - Human MH - Italy MH - Laboratories/*supply & distribution MH - Leptospira/classification MH - Leptospirosis/diagnosis/*epidemiology/microbiology MH - Medical Records MH - *Population Surveillance MH - Registries MH - Serotyping PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Jul 31 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 243-8 SB - M CY - ITALY IP - 3 VI - 63 JC - AKG AA - Author EM - 8504 AB - A geographic emplacement of reference Centres for the epidemiological control is proposed here according to recommendation by the Istituto Superiore di Sanita and the instructions of the WHO. While the ordinary laboratories make serodiagnosis for clinical use only, the reference Centres must carry out the epidemiological control by typing of leptospires strains in order to establish the prevalence of the serotypes in the different territories. For these more complex epidemiological techniques, closer relations between the Centres and the Istituto Superiore di Sanita are necessary. The national map proposed, object of discussion at the meeting, refers to reference Centres (location and person) that have made themselves available for this duty. PMID- 6508947 CU - 88 TT - Individuazione dei laboratori preposti alla sorveglianza delle leptospirosi a livello regionale e pluriregionale. EA - A SO - Boll Ist Sieroter Milan 1984 Jul 31;63(3):243-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85072594 AU - Cacciapuoti B TI - [The diagnosis of leptospirosis in the hospital microbiology laboratory] LA - Ita MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - English Abstract MH - Human MH - Laboratories MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*diagnosis/immunology/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Jul 31 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 237-43 SB - M CY - ITALY IP - 3 VI - 63 JC - AKG AA - Author EM - 8504 AB - Confirmatory diagnosis of clinical leptospirosis may be achieved by each hospital laboratory performing all-purpose bacteriological methods. Direct microscopic examination of blood may frequently demonstrate circulating leptospiras in the first few days of pyrexia. Leptospiras may be tentatively cultured from blood in the same initial period of illness, in fluid semisynthetic commercial media according to the original Ellinghausen medium. Sero-conversion for leptospira antibodies is constantly observed on two serum samples taken in the first few days of illness and ten days thereafter respectively, in each case of current leptospirosis. PMID- 6508946 CU - 91 TT - La diagnosi di leptospirosi nel laboratorio microbiologico ospedaliero. EA - A SO - Boll Ist Sieroter Milan 1984 Jul 31;63(3):237-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 85072593 AU - Mailloux M AU - Mazzonelli J AU - Dorta de Mazzonelli GT AU - Dufresne Y TI - [Biological diagnosis of the leptospiroses: technics and interpretations] LA - Ita MH - Antibodies, Bacterial/analysis MH - English Abstract MH - Human MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*diagnosis/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Jul 31 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 233-6 SB - M CY - ITALY IP - 3 VI - 63 JC - AKG AA - Author EM - 8504 AB - According to the chronological data of Physio-Pathology of leptospiroses, diagnosis is: Direct: isolation of the germ in the beginning of the acute phase of the disease: blood culture, culture of cerebrospinal fluid, animal inoculation. Identification is the work of a specialized laboratory. Indirect: demonstration of antibodies. Immunological tests are divided into two groups: Screening tests, available for all laboratories: they give an indication of Leptospirosis. They are carried out during the acute phase: slide macroscopic agglutination test, hemagglutination test, complement fixation test. Confirmatory tests, performed only by specialized laboratories. Interpretation is dependent on the case history of the patient. PMID- 6508945 CU - 91 TT - Diagnostic biologique des leptospiroses: techniques et interpretation. EA - A SO - Boll Ist Sieroter Milan 1984 Jul 31;63(3):233-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 85072592 AU - Rigoli E TI - [Introduction to the Round Table on Leptospirosis] LA - Ita MH - Animal MH - English Abstract MH - Human MH - *Leptospirosis PT - JOURNAL ARTICLE DA - 850221 DP - 1984 Jul 31 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 231-2 SB - M CY - ITALY IP - 3 VI - 63 JC - AKG AA - Author EM - 8504 AB - The renewed interest in leptospirosis derives from the expansion of this infection which, broken out from its historical strictly professional role, now interests wider categories of the population, represented by frequenters of zones with water or swamp for sport or week-ends. A greater knowledge therefore is needed on the diffusion of leptospirosis and its epidemiology which is notoriously non-homogeneous and variable. The necessity for the meeting arose from this new reality, not sufficiently known, of this infection, and from the necessity to cover the national territory with reference centres coordinated by the Istituto Superiore di Sanita and in the more general epidemiological picture promoted by the WHO. PMID- 6508944 TT - Introduzione alla tavola rotonda sulla leptospirosi. EA - A SO - Boll Ist Sieroter Milan 1984 Jul 31;63(3):231-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84245709 AU - Shaunak S AU - Brettle RP AU - Inglis JM AU - Holmes L TI - More on leptospirosis [letter] LA - Eng MH - Adult MH - Animal MH - Case Report MH - Cats MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Human MH - Leptospirosis/*transmission/veterinary MH - Male MH - *Zoonoses PT - LETTER DA - 840813 DP - 1984 Jul 26 IS - 0028-4793 TA - N Engl J Med PG - 261-2 SB - A SB - M SB - X CY - UNITED STATES IP - 4 VI - 311 JC - NOW EM - 8410 PMID- 6738629 CU - 91 SO - N Engl J Med 1984 Jul 26;311(4):261-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84219648 AU - Krick WK TI - Prophylaxis against leptospirosis with doxycycline [letter] LA - Eng MH - Doxycycline/*therapeutic use MH - Human MH - Leptospirosis/*prevention & control RN - 564-25-0 (Doxycycline) PT - LETTER DA - 840720 DP - 1984 Jul 5 IS - 0028-4793 TA - N Engl J Med PG - 54 SB - A SB - M SB - X CY - UNITED STATES IP - 1 VI - 311 JC - NOW EM - 8409 PMID- 6727968 CU - 91 SO - N Engl J Med 1984 Jul 5;311(1):54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 85092783 AU - Schmid GP AU - Steigerwalt AG AU - Johnson S AU - Barbour AG AU - Steere AC AU - Robinson IM AU - Brenner DJ TI - DNA characterization of Lyme disease spirochetes. LA - Eng MH - Borrelia/classification MH - Cytosine/metabolism MH - DNA, Bacterial/*metabolism MH - Guanine/metabolism MH - Human MH - Leptospira/classification MH - Lyme Disease/*microbiology MH - Species Specificity MH - Spirochaetales/*classification MH - Treponema/classification RN - 0 (DNA, Bacterial) RN - 71-30-7 (Cytosine) RN - 73-40-5 (Guanine) PT - JOURNAL ARTICLE DA - 850215 DP - 1984 Jul-Aug IS - 0044-0086 TA - Yale J Biol Med PG - 539-42 SB - M CY - UNITED STATES IP - 4 VI - 57 JC - XR7 AA - Author EM - 8504 AB - Lyme disease spirochetes (LDS) have phenotypic characteristics of both treponemes and borreliae. To ascertain whether one or more species of LDS exist, as well as their taxonomic status, we determined the DNA base (G + C) content for three strains of LDS, the DNA relatedness of ten strains isolated in the United States or Europe, and the DNA relatedness of LDS to other spirochetes. The G + C content of the three LDS strains was 28.1-29.0 mol%, most similar to those of Borellia hermsii (30.6 mol %) and Treponema hyodysenteriae (25.6 mol %) among the other spirochetes tested. DNA hybridization studies of nine LDS strains to a reference strain isolated from human blood revealed divergence (unpaired bases) within related nucleotide sequences of only 0.0-1.0 percent, indicating the strains were one species. Similarly, relatedness values of seven strains to the reference strain were high: 58-98 percent (mean, 71 percent) in 50 degrees C reactions and 50-93 percent (mean, 69 percent) in 65 degrees C reactions. Labeled DNA from B. hermsii was 30-40 percent related to three Lyme disease spirochete strains in 50 degrees C reactions and 8-10 percent related in 65 degrees C reactions. In contrast, DNA from the reference LDS strain showed relatedness of only 1 percent to DNAs of two leptospires and only 16 percent to DNA from T. hyodysenteriae. We conclude that LDS are a single species, genetically unlike treponemes or leptospires, which belong in the genus Borrelia. PMID- 6516455 CU - 91 SO - Yale J Biol Med 1984 Jul-Aug;57(4):539-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 85087494 AU - McGrath H AU - Adler B AU - Vinh T AU - Faine S TI - Phagocytosis of virulent and avirulent leptospires by guinea-pig and human polymorphonuclear leukocytes in vitro. LA - Eng MH - Animal MH - Complement/immunology MH - Guinea Pigs MH - Human MH - Immune Sera/immunology MH - In Vitro MH - *Leptospira/pathogenicity MH - Luminescence MH - Microscopy, Electron MH - Neutrophils/*immunology/ultrastructure MH - *Phagocytosis MH - Support, Non-U.S. Gov't MH - Virulence RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 850205 DP - 1984 Jul IS - 0031-3025 TA - Pathology PG - 243-9 SB - M CY - AUSTRALIA IP - 3 VI - 16 JC - OTA AA - Author EM - 8504 AB - Chemiluminescence (CL) and electron microscopy were used to study the phagocytosis of both virulent and avirulent strains of Leptospira interrogans serovar copenhageni by guinea-pig and human polymorphonuclear leukocytes (PMN). A significant CL response was observed when guinea-pig PMN were incubated with virulent leptospires in the presence but not in the absence of specific immune serum. This response was markedly enhanced by the addition of guinea-pig complement. Phagocytosis was confirmed by the observation of intracellular leptospires in guinea-pig PMN by electron microscopy. The phagocytosis of avirulent leptospires by guinea-pig PMN and of both virulent and avirulent leptospires by human PMN required the presence of both specific immune serum and complement. Thus the ability of leptospires to resist phagocytosis by PMN in the absence of immune serum does not appear to be a major determinant of virulence. PMID- 6514391 SO - Pathology 1984 Jul;16(3):243-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [87 medline neighbors] UI - 84301946 AU - Lev MI AU - Tatarnikov VM AU - Shishko VP AU - Trop IE AU - Kleshnev MV TI - [Clinico-epidemiological aspects of leptospiral jaundice in Khabarovsk Territory] LA - Rus MH - Animal MH - Animals, Domestic MH - Antibodies, Bacterial/analysis MH - Human MH - Leptospira interrogans/immunology MH - Siberia MH - Weil's Disease/*diagnosis/epidemiology/veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 841022 DP - 1984 Jul IS - 0026-9050 TA - Voen Med Zh PG - 36-7 CY - USSR IP - 7 JC - XGS EM - 8412 PMID- 6474890 CU - 91 TT - Kliniko-epidemiologicheskie aspekty zheltushnogo leptospira v Khabarovskom krae. SO - Voen Med Zh 1984 Jul;(7):36-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 85092782 AU - Johnson RC AU - Hyde FW AU - Rumpel CM TI - Taxonomy of the Lyme disease spirochetes. LA - Eng MH - *Bacteriological Techniques MH - Culture Media MH - DNA, Bacterial/metabolism MH - Energy Metabolism MH - Human MH - Lyme Disease/*microbiology MH - Microscopy, Electron, Scanning MH - Species Specificity MH - Spirochaetales/*classification/metabolism/ultrastructure MH - Support, U.S. Gov't, P.H.S. RN - 0 (Culture Media) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE ID - AI 18153/AI/NIAID DA - 850215 DP - 1984 Jul-Aug IS - 0044-0086 TA - Yale J Biol Med PG - 529-37 SB - M CY - UNITED STATES IP - 4 VI - 57 JC - XR7 AA - Author EM - 8504 AB - Morphology, physiology, and DNA nucleotide composition of Lyme disease spirochetes, Borrelia, Treponema, and Leptospira were compared. Morphologically, Lyme disease spirochetes resemble Borrelia. They lack cytoplasmic tubules present in Treponema, and have more than one periplasmic flagellum per cell end and lack the tight coiling which are characteristic of Leptospira. Lyme disease spirochetes are also similar to Borrelia in being microaerophilic, catalase-negative bacteria. They utilize carbohydrates such as glucose as their major carbon and energy sources and produce lactic acid. Long-chain fatty acids are not degraded but are incorporated unaltered into cellular lipids. The diamino amino acid present in the peptidoglycan is ornithine. The mole % guanine plus cytosine values for Lyme disease spirochete DNA were 27.3-30.5 percent. These values are similar to the 28.0-30.5 percent for the Borrelia but differed from the values of 35.3-53 percent for Treponema and Leptospira. DNA reannealing studies demonstrated that Lyme disease spirochetes represent a new species of Borrelia, exhibiting a 31-59 percent DNA homology with the three species of North American borreliae. In addition, these studies showed that the three Lyme disease spirochetes comprise a single species with DNA homologies ranging from 76-100 percent. The three North American borreliae also constitute a single species, displaying DNA homologies of 75-95 percent. Lyme disease spirochetes and Borrelia exhibited little or no DNA homology (0-2 percent) with the Treponema or Leptospira. Plasmids were present in the three Lyme disease spirochetes and the three North American borreliae. PMID- 6393605 CU - 96 SO - Yale J Biol Med 1984 Jul-Aug;57(4):529-37 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84233100 TI - Leptospirosis in man, British Isles, 1983. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Child MH - Disease Outbreaks/veterinary MH - Female MH - Great Britain MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Male MH - Middle Age MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 840803 DP - 1984 Jun 30 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 1984-5 SB - A SB - M SB - X CY - ENGLAND IP - 6435 VI - 288 JC - B4X EM - 8410 PMID- 6428631 CU - 91 NI - A SO - Br Med J (Clin Res Ed) 1984 Jun 30;288(6435):1984-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84233099 AU - Hart RJ AU - Gallagher J AU - Waitkins S TI - An outbreak of leptospirosis in cattle and man. LA - Eng MH - Adult MH - Agricultural Workers' Diseases/*epidemiology MH - Animal MH - Case Report MH - Cattle MH - Cattle Diseases/*epidemiology MH - Disease Outbreaks/*veterinary MH - England MH - Female MH - Human MH - Leptospirosis/*epidemiology/transmission/veterinary MH - Male PT - JOURNAL ARTICLE DA - 840803 DP - 1984 Jun 30 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 1983-4 SB - A SB - M SB - X CY - ENGLAND IP - 6435 VI - 288 JC - B4X EM - 8410 PMID- 6428630 CU - 91 SO - Br Med J (Clin Res Ed) 1984 Jun 30;288(6435):1983-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84223917 AU - Alexander AD TI - Leptospirosis in laboratory mice [letter] LA - Eng MH - Animal MH - Animals, Laboratory/*microbiology MH - Dogs MH - Human MH - Leptospira MH - Leptospirosis/*microbiology/transmission MH - Mice MH - Mice, Inbred ICR MH - Primates MH - Rats PT - LETTER DA - 840702 DP - 1984 Jun 15 IS - 0036-8075 TA - Science PG - 1158 SB - M SB - X CY - UNITED STATES IP - 4654 VI - 224 JC - UJ7 EM - 8409 PMID- 6729449 CU - 91 SO - Science 1984 Jun 15;224(4654):1158 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 84261119 AU - Weihe WH TI - [A case of acute leptospirosis of a dog and a man in an experimental animal unit] LA - Ger MH - Animal MH - Animals, Laboratory MH - Antibodies, Bacterial/analysis MH - Dog Diseases/*diagnosis MH - Dogs MH - English Abstract MH - Human MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis/transmission/*veterinary MH - Male MH - Quarantine RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840919 DP - 1984 Jun 8 IS - 0341-6593 TA - DTW Dtsch Tierarztl Wochenschr PG - 227-30 CY - GERMANY, WEST IP - 6 VI - 91 JC - ECT EM - 8411 PMID- 6378582 CU - 91 TT - Ein Fall von akuter Leptospirose von Hund und Mensch in einer Versuchstierhaltung. EA - A SO - DTW Dtsch Tierarztl Wochenschr 1984 Jun 8;91(6):227-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84245936 AU - Terpstra WJ AU - Bercovich Z TI - [Milkers' fever, the leptospirosis of cattlemen] LA - Dut MH - Adult MH - Aged MH - Animal MH - Case Report MH - Cattle MH - Cattle Diseases/transmission MH - *Dairying MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology/transmission/veterinary MH - Male MH - Middle Age MH - Netherlands MH - Occupational Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 840815 DP - 1984 Jun 2 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 1040-4 CY - NETHERLANDS IP - 22 VI - 128 JC - NUK EM - 8410 PMID- 6738729 CU - 88 TT - Melkerskoorts, de leptospirose van veehouders. EA - A SO - Ned Tijdschr Geneeskd 1984 Jun 2;128(22):1040-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 84245484 AU - Snider EL TI - Dairy herd health management. LA - Eng MH - *Anestrus/drug effects MH - Animal MH - Antibiotics/therapeutic use MH - Bacterial Infections/drug therapy/prevention & control/veterinary MH - Cattle MH - Cattle Diseases/*therapy MH - *Dairying MH - Endometritis/drug therapy/veterinary MH - *Estrus/drug effects MH - Female MH - Mastitis, Bovine/*prevention & control MH - Pregnancy MH - Puerperal Disorders/therapy/*veterinary MH - Vaccination/*veterinary RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 840822 DP - 1984 Jun IS - 0362-8140 TA - Mod Vet Pract PG - 467-9 SB - M CY - UNITED STATES IP - 6 VI - 65 JC - NGO AA - Author EM - 8410 AB - Estrual cows are more likely to be recognized if penned with other open cows. Cycling cows fresh less than 100 days, without signs of heat or a follicle but with good uterine tone and signs of ovarian activity, are closely observed for heat 15-20 days after examination. Those fresh at least 150 days are given prostaglandin. Lugol's iodine solution is infused into the uterus of cows without signs of ovarian activity but with normal uterine tone. Cows with retained fetal membranes are given an intrauterine infusion of oxytetracycline with the membranes being removed only if it will not damage the uterus. Oxytetracycline or chlorhexidine solution is infused into the uterus of cows with a purulent vulvar discharge 2 or more weeks postpartum. Prostaglandins may benefit cows not showing signs of heat by 21 days postpartum. Procaine penicillin G solution is infused if the uterus is abnormal at 60 days postpartum. Heifers are vaccinated against brucellosis, blackleg, leptospirosis, IBR-PI3 and BVD at 4-11 months of age, with an optional Vibrio vaccination if a bull is used in the herd. Cows are given IBR-PI3, BVD and Leptospira vaccines a few days post-partum, with a Leptospira booster at pregnancy examination. Cows with Streptococcus mastitis in late lactation may best be treated by drying off. Control of coliform mastitis necessitates a clean barn and milking parlor environment. Staphylococcus mastitis may require segregation of affected cows and installation of a low-line milker to prevent spread. PMID- 6738523 CU - 91 SO - Mod Vet Pract 1984 Jun;65(6):467-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84239268 AU - Hanson LE TI - Treatment of human leptospirosis [letter] LA - Eng MH - Animal MH - Doxycycline/*therapeutic use MH - Human MH - Leptospirosis/*drug therapy RN - 564-25-0 (Doxycycline) PT - LETTER DA - 840807 DP - 1984 Jun 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1318 SB - M CY - UNITED STATES IP - 11 VI - 184 JC - HAV EM - 8410 PMID- 6735851 CU - 91 SO - J Am Vet Med Assoc 1984 Jun 1;184(11):1318 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85008684 AU - Ono E AU - Naiki M AU - Yanagawa R TI - Isolation of an antigenic oligosaccharide fraction from Leptospira interrogans serovar canicola with a monoclonal antibody. LA - Eng MH - *Antibodies, Monoclonal MH - Antigens, Bacterial/*analysis MH - Chromatography, Gel MH - Chromatography, High Pressure Liquid MH - Chromatography, Thin Layer MH - Enzyme-Linked Immunosorbent Assay MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Oligosaccharides/*analysis MH - Phosphatidylethanolamines/metabolism MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Oligosaccharides) RN - 0 (Phosphatidylethanolamines) PT - JOURNAL ARTICLE DA - 841101 DP - 1984 Jun IS - 0022-1287 TA - J Gen Microbiol PG - 1429-35 SB - M CY - ENGLAND VI - 130 ( Pt 6) JC - I87 AA - Author EM - 8501 AB - An oligosaccharide fraction containing the antigenic determinant of lipopolysaccharide antigen (TM antigen) from Leptospira interrogans serovar canicola, recognized by a monoclonal antibody (CT3) which agglutinates serovars canicola and broomi, was isolated by formic acid and successive sulphuric acid hydrolyses. Separation of the antigenic compounds was done by Bio-Gel P-2 and Sephadex G-25 gel filtration, and high-performance liquid chromatography with two different columns. The fraction finally obtained was a mixture of two oligosaccharides, both of which migrated as a single spot having a slightly higher mobility than an authentic tetrasaccharide (stachyose) on thin layer chromatography. The fraction contained rhamnose, arabinose and two major and two minor unknown sugars which were shown to be N- or O- acetylated and/or O-methylated sugars by nuclear magnetic resonance. The fraction inhibited the binding of CT3 antibody with TM antigen in enzyme-linked immunosorbent assay and microscopic agglutination of serovar canicola with the antibody. The inhibitory activity was destroyed by periodate oxidation or mild alkaline treatment, but was resistant to sodium borohydride reduction. PMID- 6481337 CU - 92 SO - J Gen Microbiol 1984 Jun;130 ( Pt 6):1429-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 84289863 AU - Jones CJ AU - Sulzer KR AU - Everard CO AU - Vaughn AW AU - Innis VA TI - Bim, a new serovar of Leptospira interrogans isolated from a dog in Barbados. LA - Eng MH - Animal MH - Barbados MH - Dogs/*microbiology MH - Human MH - Kidney/*microbiology MH - Leptospira interrogans/classification/*isolation & purification MH - Nomenclature MH - Serotyping MH - Support, Non-U.S. Gov't MH - Weil's Disease/microbiology PT - JOURNAL ARTICLE DA - 840926 DP - 1984 Jun IS - 0095-1137 TA - J Clin Microbiol PG - 946 SB - M CY - UNITED STATES IP - 6 VI - 19 JC - HSH AA - Author EM - 8412 AB - A new serovar of Leptospira interrogans was isolated from a dog in Barbados. The proposed name of the new serovar is bim, and the designated type strain is 1051. The serogroup of the new serovar is the Autumnalis serogroup. The new serovar was subsequently isolated from six patients with leptospirosis in Barbados. PMID- 6470107 SO - J Clin Microbiol 1984 Jun;19(6):946 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 84289862 AU - Liceras de Hidalgo JL AU - Sulzer KR TI - Six new leptospiral serovars isolated from wild animals in Peru. LA - Eng MH - Animal MH - Animals, Wild/microbiology MH - Guinea Pigs MH - Leptospira interrogans/classification/*isolation & purification/pathogenicity MH - Nomenclature MH - Opossums/*microbiology MH - Peru MH - Serotyping MH - Virulence PT - JOURNAL ARTICLE DA - 840926 DP - 1984 Jun IS - 0095-1137 TA - J Clin Microbiol PG - 944-5 SB - M CY - UNITED STATES IP - 6 VI - 19 JC - HSH AA - Author EM - 8412 AB - Six new serovars of Leptospira interrogans were isolated from opossums (Didelphis marsupialis and Philander opossum) trapped in the Peruvian jungle. The proposed names, type strain designation, and serogroup of the serovars, respectively, were: huallaga, strain M-7, Djasiman serogroup; luis, strain M-6, Tarassovi serogroup; machiguenga, strain MMD-3, Icterohaemorrhagiae serogroup; rioja, strain MR-12, Bataviae serogroup; rupa rupa, strain M-3, Sejroe serogroup; and tingomaria, strain M-13, Cynopteri serogroup. PMID- 6470106 CU - 90 SO - J Clin Microbiol 1984 Jun;19(6):944-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 84268888 AU - Shuvalova EP AU - Rakhmanova AG AU - Antonova TV TI - [Characteristics of the pathogenesis of the hemorrhagic syndrome in viral hepatitis and the icteric form of leptospirosis] LA - Rus MH - Epistaxis/etiology MH - Eye Diseases/etiology MH - Hemorrhage/*etiology MH - Hepatitis, Viral, Human/*blood MH - Human MH - Purpura/etiology MH - Sclera MH - Syndrome MH - Thrombocytopenia/*complications MH - Weil's Disease/*blood PT - JOURNAL ARTICLE DA - 840904 DP - 1984 May IS - 0023-2149 TA - Klin Med (Mosk) PG - 93-6 CY - USSR IP - 5 VI - 62 JC - KW2 EM - 8411 PMID- 6748589 CU - 90 TT - Osobennosti patogeneza gemorragicheskogo sindroma pri virusnom gepatite i zheltushnoi forme leptospiroza. SO - Klin Med (Mosk) 1984 May;62(5):93-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [70 medline neighbors] UI - 84255924 AU - Kefford B AU - Marshall KC TI - Adhesion of Leptospira at a solid-liquid interface: a model. LA - Eng MH - Comparative Study MH - Leptospira/*physiology MH - *Models, Biological MH - Movement MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 840808 DP - 1984 May IS - 0302-8933 TA - Arch Microbiol PG - 84-8 SB - M CY - GERMANY, WEST IP - 1 VI - 138 JC - 7YN AA - Author EM - 8410 AB - Two strains of the saprophytic Leptospira biflexa serovar patoc display reversible and irreversible adhesion at a solid-liquid interface. Both forms of adhesion are enhanced in the presence of 20 microM carbonyl cyanide meta-chlorophenyl hydrazone (CCCP), an uncoupler which inhibits motility of the bacteria. Microscopic observations also indicated that motility may have a role in adhesion as only actively motile organisms were seen to detach from the substratum. A dynamic model is proposed for adhesion of these organisms at a solid-liquid interface. It is suggested that the level of reversible adhesion is determined by the comparative rates of attachment (ON phase) and detachment (OFF phase). As reversible adhesion is mediated by weak forces of attraction, bacterial motility or gentle washing could promote the OFF phase. When motility is inhibited, the OFF phase is reduced and the ON phase continues (as motility is not required for the ON phase) causing the level of reversible adhesion to increase. Since reversible adhesion is a prerequisite for irreversible adhesion, then increased reversible adhesion leads directly to increased irreversible adhesion. Reversible adhesion appears to be mediated by the weak attractive forces of the "secondary minimum" whereas the mechanism facilitating irreversible adhesion of leptospires is not known. PMID- 6742958 SO - Arch Microbiol 1984 May;138(1):84-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 84184714 AU - Wang B AU - Sullivan J AU - Sullivan GW AU - Mandell GL TI - Interaction of leptospires with human polymorphonuclear neutrophils. LA - Eng MH - Human MH - Leptospira/growth & development/*physiology/ultrastructure MH - Leptospira interrogans/*physiology MH - Microscopy, Electron MH - Microscopy, Electron, Scanning MH - Neutrophils/*physiology/ultrastructure MH - Phagocytosis MH - Support, U.S. Gov't, P.H.S. MH - Time Factors PT - JOURNAL ARTICLE ID - AIO9504 DA - 840613 DP - 1984 May IS - 0019-9567 TA - Infect Immun PG - 459-64 SB - M SB - X CY - UNITED STATES IP - 2 VI - 44 JC - GO7 AA - Author EM - 8408 AB - The role of the polymorphonuclear neutrophils (PMN) in defense against leptospires has not been adequately studied, in part, because of difficulty in quantitating pathogenic leptospires. By using pour plates to quantitate nonpathogenic leptospires and the most-probable-number procedure to quantitate the pathogenic leptospires, we examined the interactions of nonpathogenic Leptospira biflexa and pathogenic Leptospira interrogans serovar icterohemorrhagiae with human neutrophils. Phase-contrast, scanning electron, and transmission electron microscopic observations were made. Leptospires were incubated with PMN at 37 degrees C and tumbled together. There was no ingestion or killing of nonpathogenic leptospires (with no serum) or of pathogenic organisms (with 10% normal serum). However, when leptospires were incubated with PMN (without serum) in a pellet and then resuspended, 91 +/- 6% of nonpathogenic leptospires were removed from the supernatant, and 93 +/- 4% of these organisms were killed. The pathogenic leptospires became cell associated in a pellet, but were not killed by PMN even in the presence of 10% normal serum. Observations of morphological interactions indicated that PMN phagocytized the nonpathogenic leptospires in the absence of serum and that the pathogenic leptospires attached to but were not ingested by neutrophils in the presence of 10% normal serum. PMN do not seem to be an efficient defense factor for pathogenic leptospires in nonimmune hosts. The virulence of leptospires appears to be related to their ability to resist killing by serum and to resist ingestion and killing by neutrophils. PMID- 6715045 CU - 90 SO - Infect Immun 1984 May;44(2):459-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84176881 AU - McClain JB AU - Ballou WR AU - Harrison SM AU - Steinweg DL TI - Doxycycline therapy for leptospirosis. LA - Eng MH - Double-Blind Method MH - Doxycycline/*therapeutic use MH - Drug Evaluation MH - Human MH - Leptospirosis/*drug therapy MH - Military Medicine MH - Random Allocation RN - 564-25-0 (Doxycycline) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - RANDOMIZED CONTROLLED TRIAL DA - 840511 DP - 1984 May IS - 0003-4819 TA - Ann Intern Med PG - 696-8 SB - A SB - M SB - X CY - UNITED STATES IP - 5 VI - 100 JC - 5A6 AA - Author EM - 8407 AB - To study antibiotic efficacy, 29 patients with leptospirosis were treated in a randomized, double-blinded fashion with doxycycline, 100 mg orally twice a day, or placebo. Therapy was given for 7 days in a hospital, and patients were followed for 3 weeks afterwards. Duration of illness before therapy and severity of illness were the same in both groups. Doxycycline reduced the duration of illness by 2 days and favorably affected fever, malaise, headache, and myalgias. Treatment prevented leptospiruria and had no adverse effects. Doxycycline is effective in therapy for patients with leptospirosis. RO - M:RCT PMID- 6712032 CU - 95 SO - Ann Intern Med 1984 May;100(5):696-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84300515 AU - Zavala Velazquez J AU - Pinzon Cantarell J AU - Flores Castillo M AU - Damian Centeno AG TI - [Leptospirosis in the Yucatan. Serological study in humans and animals] LA - Spa MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/epidemiology MH - Child MH - English Abstract MH - Human MH - Leptospira/immunology MH - Leptospirosis/blood/*epidemiology/veterinary MH - Mexico MH - Middle Age MH - Swine MH - Swine Diseases/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 841022 DP - 1984 May-Jun IS - 0036-3634 TA - Salud Publica Mex PG - 254-9 CY - MEXICO IP - 3 VI - 26 JC - UY1 EM - 8412 PMID- 6474260 CU - 91 TT - La leptospirosis en Yucatan. Estudio serologico en humanos y animales. EA - A SO - Salud Publica Mex 1984 May-Jun;26(3):254-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85098787 AU - Mailloux M AU - Mazzonelli J AU - Dorta de Mazzonelli G AU - Dufresne Y TI - [The biological diagnosis of leptospirosis today] LA - Fre MH - Antibodies, Bacterial/isolation & purification MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - *Immunologic Techniques MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 850320 DP - 1984 May-Jun IS - 0001-4079 TA - Bull Acad Natl Med PG - 621-5 CY - FRANCE IP - 5-6 VI - 168 JC - B8G EM - 8505 PMID- 6394116 CU - 91 TT - Le diagnostic biologique des leptospiroses aujourd'hui. EA - A SO - Bull Acad Natl Med 1984 May-Jun;168(5-6):621-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [44 medline neighbors] UI - 84276524 AU - Mochmann H AU - Kmety E TI - [A type strain or a neotype strain of Leptospira] LA - Ger MH - Bacteriology/history MH - English Abstract MH - Germany MH - History of Medicine, 20th Cent. MH - Human MH - Japan MH - Leptospira interrogans/*classification MH - Weil's Disease/etiology/history PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE PT - REVIEW DA - 840918 DP - 1984 May IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 73-82 SB - M CY - GERMANY, WEST IP - 1 VI - 257 JC - Y55 AA - Author EM - 8411 AB - A deep review of the scientific literature concerning the history of the two oldest icterohaemorrhagiae strains is given in order to promote a decision about the legitimate neotype strain on the genus Leptospira. The strain RGA was found to meet completely the requirements for a Neotype culture given by the International Code of Nomenclature of Bacteria. Its origin from a patient with Weil's disease through guinea pig passages in 1915 is well documented and its culture is unequivocally described by Ungermann in 1916. The strain was maintained in pure culture. Since more than 60 years the strain is used for comparative investigations in classification studies in all laboratories performing such tests. At contrary the history of strain Ictero I is very incomplete. The strain was claimed by Yamamoto to be one of the strain isolated by Inada and Ido in 1915 originally designated as Yamasaki. However, the statement the maintenance of these strains because of loss of virulence was discontinued, is repeatedly mentioned in some old publications of the authors. Moreover it is reported that the strain Ictero I because of contamination with a fungus was recultivated after a passage through a splenectomized mouse, i.e. the strain was not maintained in a pure culture. Beside this it is hardly understandable why has the strain not been submitted to other laboratories before 1965. The strain Ictero I was found to contain an additional thermolabile antigen not present in RGA. At present it is impossible to decide whether this property was already present in the original culture or developed only later, eventually after its mouse passage. Summarizing all these facts, it must be stated that the strain Ictero I cannot be considered to meet all the necessary requirements of its recognition as neotype culture of the Genus Leptospira. RF - 33 PMID- 6380158 CU - 90 TT - Zur Frage eines Typstammes beziehungsweise Neotypstammes fur die Leptospiren. EA - A SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 May;257(1):73-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 84237566 AU - Yelton DB AU - Charon NW TI - Cloning of a gene required for tryptophan biosynthesis from Leptospira biflexa serovar patoc into Escherichia coli. LA - Eng MH - Chromosome Mapping MH - *Cloning, Molecular MH - Drug Resistance, Microbial MH - DNA, Recombinant MH - Escherichia coli/*genetics/metabolism MH - *Genes, Bacterial MH - Leptospira/*genetics MH - Nucleic Acid Hybridization MH - Plasmids MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Transformation, Bacterial MH - Tryptophan/*biosynthesis/genetics RN - 0 (DNA, Recombinant) RN - 0 (Plasmids) RN - 6912-86-3 (Tryptophan) PT - JOURNAL ARTICLE ID - DEO4645 ID - 5 SO7-RRO5433-18 DA - 840803 DP - 1984 May IS - 0378-1119 TA - Gene PG - 147-52 SB - M CY - NETHERLANDS IP - 2 VI - 28 JC - FOP AA - Author EM - 8410 AB - A clone bank, consisting of approx. 8100 colonies, has been created for the spirochete Leptospira biflexa serovar patoc in Escherichia coli using pBR322 as the vector. One of these clones contains the genetic information needed to complement a defect in the trpE gene of E. coli. The information resides on a 20.5-kb plasmid designated pYC1, which carries a 16-kb insert consisting of three HindIII fragments. It does not complement defects in other genes needed for the biosynthesis of tryptophan in E. coli. PMID- 6376283 CU - 92 SO - Gene 1984 May;28(2):147-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84214325 AU - Craft JE AU - Grodzicki RL AU - Steere AC TI - Antibody response in Lyme disease: evaluation of diagnostic tests. LA - Eng MH - Antibodies, Bacterial/*analysis MH - Arthritis, Infectious/diagnosis/*immunology MH - Comparative Study MH - Cross Reactions MH - Enzyme-Linked Immunosorbent Assay MH - Fluorescent Antibody Technique MH - Human MH - IgG/*analysis MH - IgM/*analysis MH - Leptospirosis/immunology MH - Relapsing Fever/immunology MH - Spirochaetales/*immunology MH - Spirochaetales Infections/*immunology MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Syphilis/immunology MH - Ticks/microbiology MH - Time Factors RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE ID - AM-20358/AM/NIADDK ID - AM-07107/AM/NIADDK ID - AM-5639/AM/NIADDK ID - + DA - 840718 DP - 1984 May IS - 0022-1899 TA - J Infect Dis PG - 789-95 SB - A SB - M CY - UNITED STATES IP - 5 VI - 149 JC - IH3 AA - Author EM - 8409 AB - The antibody response to the Ixodes dammini spirochete was determined in 41 serial serum samples from 12 patients with Lyme disease. By enzyme-linked immunosorbent assay (ELISA), 11 of the 12 patients had higher titers of specific IgM antibody (greater than 1:200) during early disease than did 40 control subjects. Specific IgM antibody titers, which correlated with total amounts of IgM antibody (P less than .001), sometimes remained elevated throughout the illness. During neuritis, nine of 10 patients had higher specific IgG antibody titers (greater than 1:200) than did controls, and when arthritis was present, all had such titers, which remained elevated after months of remission. In the ELISA, antibody responses determined by single or serial dilutions were similar, but the ELISA was more sensitive and specific than was immunofluorescence. Adsorption of sera with Borrelia hermsii generally resulted in a fourfold decrease in titers of cross-reactive antibodies, but the titers of sera from patients with Lyme disease were also reduced. Currently, the ELISA, without adsorption, is the best diagnostic test for Lyme disease. PMID- 6373966 CU - 96 SO - J Infect Dis 1984 May;149(5):789-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 84225683 AU - Hathaway SC AU - Wilesmith JW AU - Little TW TI - Some population parameters of Leptospira interrogans serovar hardjo infection in sheep. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/epidemiology MH - England MH - Female MH - Leptospira interrogans/immunology MH - Pregnancy MH - Sheep/immunology MH - Sheep Diseases/*epidemiology MH - Wales MH - Weil's Disease/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840625 DP - 1984 Apr 28 IS - 0042-4900 TA - Vet Rec PG - 428-9 SB - M CY - ENGLAND IP - 17 VI - 114 JC - XBS EM - 8409 PMID- 6730262 CU - 91 SO - Vet Rec 1984 Apr 28;114(17):428-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [194 medline neighbors] UI - 84252469 AU - Prokopcakova G AU - Pospisil R TI - [Results of serological surveys for leptospirosis in animals and people in the environs of 2 water reservoirs in eastern Slovakia] LA - Rus MH - Animal MH - Carrier State/*diagnosis/epidemiology/veterinary MH - Cattle MH - Cattle Diseases/diagnosis/epidemiology MH - Czechoslovakia MH - Disease Reservoirs/veterinary MH - Disease Vectors MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis/epidemiology/veterinary MH - Rodentia/immunology MH - Serodiagnosis MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 840801 DP - 1984 Apr IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 56-8 SB - M CY - USSR IP - 4 JC - Y9O AA - Author EM - 8410 AB - The authors present the results of serological surveys for leptospirosis in rodents, cattle and humans, carried out in the vicinity of two large water reservoirs in Eastern Slovakia. Of the total number of 243 rodents covered by the surveys, 8.2% yielded positive reactions with leptospiral antigens. In most cases the sera reacted with L. grippotyphosa and L. sejroe . Of 168 samples of cattle serum, 13 serum samples, i.e. 7.7.%, yielded positive reactions, also with L. sejroe and L. grippotyphosa. In the group of serum samples obtained from humans, 28 out of 876 samples studied in the surveys, i. e. 3.1%, were positive. Among humans 6 serotypes were established; of these, L. sejroe occurred most frequently among humans, and also among domestic animals and rodents, then followed L. bratislava and L. grippotyphosa. The positive results obtained in humans, cattle and rodents with the prevalence of the same serotypes indicate the existence of close contacts of humans with animals, as well as the possibility of acquiring water-borne infection in recreation zones. PMID- 6741358 CU - 88 TT - Rezul'taty serologicheskikh obsledovanii na leptospiroz zhivotnykh i liudei v okrestnostiakh dvukh vodokhranilishch v Vostochnoi Slovakii. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1984 Apr;(4):56-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84252432 AU - Ballard SA AU - Adler B AU - Millar BD AU - Chappel RJ AU - Jones RT AU - Faine S TI - The immunoglobulin response of swine following experimental infection with Leptospira interrogans serovar pomona. LA - Eng MH - Animal MH - *Antibody Formation MH - Enzyme-Linked Immunosorbent Assay MH - IgG/metabolism MH - IgM/metabolism MH - Immunoglobulins/*metabolism MH - Leptospira interrogans/immunology MH - Serotyping MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*immunology MH - Weil's Disease/immunology/*veterinary PT - JOURNAL ARTICLE DA - 840822 DP - 1984 Apr IS - 0040-3603 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 510-7 SB - M CY - GERMANY, WEST IP - 4 VI - 256 JC - Y55 AA - Author EM - 8410 AB - The antibody response of pigs following experimental infection with Leptospira interrogans serovar pomona was examined using enzyme immunoassay (EIA) and the microscopic agglutination test (MAT). Leptospires elicited the production of both IgM and IgG classes of antibody, with IgG levels persisting for much longer than IgM. A comparison of MAT and EIA indicated that the detection of specific IgM by EIA was potentially useful in distinguishing between past and recent infection in pigs. Agglutinins were also detected in the urine of infected animals but these antibodies could not be detected by EIA. PMID- 6741345 CU - 90 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1984 Apr;256(4):510-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 84251906 AU - Bogachik LI AU - Vasil'eva NA AU - Sokol AN AU - Bogachik NA AU - Ishchuk IS TI - [Clinico-epidemiological analysis of leptospirosis in various regions] LA - Rus MH - Adult MH - Case Report MH - Child MH - Diagnostic Errors MH - Drug Therapy, Combination MH - English Abstract MH - Female MH - Human MH - Leptospirosis/diagnosis/drug therapy/*epidemiology MH - Male MH - Ukraine PT - JOURNAL ARTICLE DA - 840802 DP - 1984 Apr IS - 0049-6804 TA - Vrach Delo PG - 114-6 CY - USSR IP - 4 JC - XLS EM - 8410 PMID- 6741041 CU - 88 TT - Kliniko-epidemiologicheskii analiz leptospiroza v nekotorykh regionakh. EA - A SO - Vrach Delo 1984 Apr;(4):114-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 84243049 AU - Bourque M AU - Higgins R TI - Serologic studies on brucellosis, leptospirosis and tularemia in moose (Alces alces) in Quebec. LA - Eng MH - Animal MH - Animals, Wild/immunology MH - Antibodies, Bacterial/analysis MH - Brucella abortus/immunology MH - Brucellosis/epidemiology/*veterinary MH - Deer/*immunology MH - Female MH - Francisella tularensis/immunology MH - Leptospira interrogans/immunology MH - Male MH - Quebec MH - Tularemia/epidemiology/*veterinary MH - Weil's Disease/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840813 DP - 1984 Apr IS - 0090-3558 TA - J Wildl Dis PG - 95-9 SB - M CY - UNITED STATES IP - 2 VI - 20 JC - KEM AA - Author EM - 8410 AB - Blood samples were obtained from 208 moose in La Verendrye and Matane Reserves and in Laurentides Park, Quebec, Canada. Sera were tested for antibodies to Brucella abortus, Leptospira interrogans serovar ballum, canicola, grippotyphosa, hardjo, icterohaemorrhagiae and pomona, and Francisella tularensis. Fifteen sera contained evidence of prior exposure to F. tularensis. Only one animal was a seroreactor to L. interrogans serovar grippotyphosa and none of them had antibodies to B. abortus. PMID- 6429355 CU - 91 SO - J Wildl Dis 1984 Apr;20(2):95-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 84205107 AU - Malkin K TI - Enhancement of Leptospira hardjo agglutination titers in sheep and goat serum by heat inactivation. LA - Eng MH - Agglutination Tests/*veterinary MH - Animal MH - Antibodies, Bacterial/analysis MH - Complement/immunology MH - Edetic Acid/pharmacology MH - False Negative Reactions MH - Goats/*immunology MH - *Heat MH - Leptospira/*immunology MH - Sheep/*immunology RN - 0 (Antibodies, Bacterial) RN - 60-00-4 (Edetic Acid) RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 840723 DP - 1984 Apr IS - 0008-4050 TA - Can J Comp Med PG - 208-10 SB - M CY - CANADA IP - 2 VI - 48 JC - CI0 AA - Author EM - 8409 AB - Heat inactivation of sheep serum samples resulted in the detection of an additional 9% reactors to Leptospira hardjo that were negative on the initial test of fresh samples. Treatment with EDTA gave results generally similar to heat inactivation suggesting that complement was responsible for the inhibition of agglutination. Tests on heat inactivated serum from experimentally infected sheep and goats revealed enhanced titers or reactions which were not detected in fresh serum. PMID- 6426764 CU - 91 SO - Can J Comp Med 1984 Apr;48(2):208-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84211993 AU - Thiermann AB TI - Leptospirosis: current developments and trends. LA - Eng MH - Abortion, Veterinary/etiology MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis/etiology/transmission MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Kidney/microbiology MH - Leptospira/immunology MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/complications/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/diagnosis MH - Vaccination MH - Weil's Disease/transmission/veterinary PT - JOURNAL ARTICLE DA - 840719 DP - 1984 Mar 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 722-5 SB - M CY - UNITED STATES IP - 6 VI - 184 JC - HAV EM - 8409 PMID- 6725107 CU - 90 SO - J Am Vet Med Assoc 1984 Mar 15;184(6):722-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84141469 AU - Faine S AU - Valentine R TI - Leptospirosis hardjo in pregnancy [letter] LA - Eng MH - Adult MH - Female MH - Fetal Diseases/diagnosis MH - Human MH - Leptospirosis/*transmission MH - Pregnancy MH - Pregnancy Complications, Infectious/*transmission PT - LETTER DA - 840326 DP - 1984 Mar 3 IS - 0025-729X TA - Med J Aust PG - 311-2 SB - M SB - X CY - AUSTRALIA IP - 5 VI - 140 JC - M26 EM - 8406 PMID- 6700482 CU - 91 SO - Med J Aust 1984 Mar 3;140(5):311-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [194 medline neighbors] UI - 84266317 AU - Kobayashi Y AU - Oyama T AU - Ninomiya T TI - [Chemotherapy of leptospirosis--effects of tobramycin, dibekacin and amikacin on the Leptospira] LA - Jpn MH - Amikacin/*pharmacology/therapeutic use MH - Dibekacin/*pharmacology/therapeutic use MH - Drug Resistance, Microbial MH - English Abstract MH - Human MH - Kanamycin/*analogs & derivatives MH - Leptospira/*drug effects MH - Leptospirosis/*drug therapy MH - Tobramycin/*pharmacology/therapeutic use RN - 32986-56-4 (Tobramycin) RN - 34493-98-6 (Dibekacin) RN - 37517-28-5 (Amikacin) RN - 59-01-8 (Kanamycin) PT - JOURNAL ARTICLE DA - 840914 DP - 1984 Mar IS - 0387-5911 TA - Kansenshogaku Zasshi PG - 197-202 CY - JAPAN IP - 3 VI - 58 JC - IJR EM - 8411 RO - M:BDS PMID- 6431032 LR - 841219 CU - 91 EA - A SO - Kansenshogaku Zasshi 1984 Mar;58(3):197-202 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 84176341 AU - Brown GW AU - Shirai A AU - Jegathesan M AU - Burke DS AU - Twartz JC AU - Saunders JP AU - Huxsoll DL TI - Febrile illness in Malaysia--an analysis of 1,629 hospitalized patients. LA - Eng MH - Adolescence MH - Adult MH - Bacterial Infections/*diagnosis MH - Child MH - Female MH - Fever/*etiology MH - Fever of Unknown Origin/etiology MH - Human MH - Leptospirosis/diagnosis MH - Malaria/*diagnosis MH - Malaysia MH - Male MH - Middle Age MH - Paratyphoid Fever/diagnosis MH - Scrub Typhus/diagnosis MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Togaviridae Infections/diagnosis MH - Typhoid/diagnosis MH - Virus Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 840510 DP - 1984 Mar IS - 0002-9637 TA - Am J Trop Med Hyg PG - 311-5 SB - A SB - M CY - UNITED STATES IP - 2 VI - 33 JC - 3ZQ AA - Author EM - 8407 AB - We studied 1,629 febrile patients from a rural area of Malaysia, and made a laboratory diagnosis in 1,025 (62.9%) cases. Scrub typhus was the most frequent diagnosis (19.3% of all illnesses) followed by typhoid and paratyphoid (7.4%); flavivirus infection (7.0%); leptospirosis (6.8%); and malaria (6.2%). The hospital mortality was very low (0.5% of all febrile patients). The high prevalence of scrub typhus in oil palm laborers (46.8% of all febrile illnesses in that group) was confirmed. In rural Malaysia, therapy with chloramphenicol or a tetracycline would be appropriate for undiagnosed patients in whom malaria has been excluded. Failure to respond to tetracycline within 48 hours would usually suggest a diagnosis of typhoid, and indicate the need for a change in therapy. PMID- 6324601 CU - 93 SO - Am J Trop Med Hyg 1984 Mar;33(2):311-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 84146816 AU - Douvier JJ AU - Ledain L AU - Besse P TI - [Leptospirosis with isolated cardiac manifestations] LA - Fre MH - Adult MH - Case Report MH - Creatine Kinase/blood MH - English Abstract MH - Human MH - Leptospirosis/*enzymology MH - Male MH - Myocarditis/enzymology/*microbiology MH - Pericarditis/enzymology/*microbiology RN - EC 2.7.3.2 (Creatine Kinase) PT - JOURNAL ARTICLE DA - 840413 DP - 1984 Mar 1 IS - 0037-1777 TA - Sem Hop PG - 701-2 SB - M CY - FRANCE IP - 10 VI - 60 JC - ULD AA - Author EM - 8406 AB - A case of leptospirosis with isolated myocardial involvement is reported. Diagnostic problems set by this uncommon clinical picture are considered. The cause of the increase in CPK and MBCPK concentrations, reflecting myolysis, is discussed. PMID- 6322319 CU - 93 TT - Leptospirose a manifestation cardiaque isolee. EA - A SO - Sem Hop 1984 Mar 1;60(10):701-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 84226742 AU - Savchenko IL AU - Vasil'chenko AA AU - Krolevetskaia NM AU - Blagodatnyi VN AU - Serebriakova TL TI - [Zoonotic infections in persons working in plants producing meat and bone meal] LA - Rus MH - Absenteeism MH - Adult MH - Animal MH - Antibodies, Bacterial/analysis MH - Dermatitis, Occupational/epidemiology MH - English Abstract MH - Human MH - *Meat-Packing Industry MH - Middle Age MH - Occupational Diseases/*epidemiology MH - Ukraine MH - Zoonoses/*epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840709 DP - 1984 Mar IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 71-3 SB - M CY - USSR IP - 3 JC - Y9O AA - Author EM - 8409 AB - The present study has revealed that persons working at offal and bone processing plants show no specific pathology, peculiar to such plants, in the state of their health and severe mass diseases among these persons are absent. Nevertheless, rather frequent occurrence of erysipeloid should be noted. The survey of workers employed at different stages of the production process has revealed the presence of ornithosis, listeriosis and leptospirosis infections. No clinically manifest cases of these diseases have been detected. The infection of individual workers occurs in the process of production as the result of contacts with infected raw materials of animal origin. For preventing the possible spread of infection great attention should be paid to sanitary, hygienic and epidemiological measures. PMID- 6233831 CU - 92 TT - K voprosu o zoonoznykh infektsiiakh u lits, rabotaiushchikh na zavodakh po proizvodstvu miaso-kostnoi muki. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1984 Mar;(3):71-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84226739 AU - Karaseva EV AU - Chernukha IuG AU - Strikhanova EV TI - [Natural focus of leptospirosis in the rice paddies of Krasmodar Territory and the means for its eradication] LA - Rus MH - Animal MH - Comparative Study MH - Disease Outbreaks/epidemiology MH - *Disease Reservoirs MH - English Abstract MH - Leptospirosis/*epidemiology/prevention & control MH - Microtinae MH - Muridae MH - Pest Control/methods MH - *Rice MH - Rodent Diseases/epidemiology MH - Russia PT - JOURNAL ARTICLE DA - 840709 DP - 1984 Mar IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 58-62 SB - M CY - USSR IP - 3 JC - Y9O AA - Author EM - 8409 AB - OFFthe rice fields of the Krasnodar Territory the intensive epizootic of leptospirosis icterohemorrhagica can be observed in the population of Norway rats (995 animals have been examined and 102 cultures obtained) the whole year round. The highest intensity of the epizootic process is known to fall on the end of summer and the beginning of autumn (45-50% of Leptospira carriers). The natural focus of leptospirosis on the rice-growing complex is epidemiologically dangerous. The epizootic process can be suppressed by reducing the population of rats by means of poisoned baits. The alternate use of different poisons ( rotindan , brodifacum ) given in the form of paraffined briquettes has proved to be most expedient. PMID- 6233830 CU - 92 TT - Prirodnyi ochag leptospiroza na risovykh poliakh Krasnodarskogo kraia i puti ego ozdorovleniia. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1984 Mar;(3):58-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84219047 AU - Ivanova LM TI - [Current epidemiology of natural focus infections in the RSFSR] LA - Rus MH - Communicable Diseases/*epidemiology MH - *Disease Reservoirs MH - Encephalitis, Tick-Borne/epidemiology MH - English Abstract MH - Hemorrhagic Fever with Renal Syndrome/epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Rural Population MH - Russia MH - Tularemia/epidemiology MH - Urban Population PT - JOURNAL ARTICLE DA - 840719 DP - 1984 Mar-Apr IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 17-21 CY - USSR IP - 2 JC - M72 EM - 8409 PMID- 6145090 CU - 94 TT - Sovremennaia epidemiologiia prirodno-ochagovykh infektsii v RSFSR. EA - A SO - Med Parazitol (Mosk) 1984 Mar-Apr;(2):17-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84181449 AU - Fanelli V TI - [Therapy of ictero-hemorrhagic leptospirosis] LA - Ita MH - Antibiotics/*therapeutic use MH - Human MH - Weil's Disease/*drug therapy RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 840607 DP - 1984 Feb 29 IS - 0009-9074 TA - Clin Ter PG - 345-9 CY - ITALY IP - 4 VI - 108 JC - DKN EM - 8408 PMID- 6232073 CU - 92 TT - Terapia della leptospirosi ittero-emorragica. SO - Clin Ter 1984 Feb 29;108(4):345-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84117404 AU - Sanford JP TI - Leptospirosis--time for a booster [editorial] LA - Eng MH - Adult MH - Human MH - Leptospirosis/*diagnosis/prevention & control PT - EDITORIAL DA - 840306 DP - 1984 Feb 23 IS - 0028-4793 TA - N Engl J Med PG - 524-5 SB - A SB - M SB - X CY - UNITED STATES IP - 8 VI - 310 JC - NOW EM - 8405 PMID- 6694697 CU - 91 SO - N Engl J Med 1984 Feb 23;310(8):524-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 84117398 AU - Takafuji ET AU - Kirkpatrick JW AU - Miller RN AU - Karwacki JJ AU - Kelley PW AU - Gray MR AU - McNeill KM AU - Timboe HL AU - Kane RE AU - Sanchez JL TI - An efficacy trial of doxycycline chemoprophylaxis against leptospirosis. LA - Eng MH - Clinical Trials MH - Double-Blind Method MH - Doxycycline/administration & dosage/*therapeutic use MH - Human MH - Leptospirosis/*prevention & control MH - Male MH - Military Medicine MH - Panama Canal Zone RN - 564-25-0 (Doxycycline) PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - RANDOMIZED CONTROLLED TRIAL DA - 840306 DP - 1984 Feb 23 IS - 0028-4793 TA - N Engl J Med PG - 497-500 SB - A SB - M SB - X CY - UNITED STATES IP - 8 VI - 310 JC - NOW AA - Author EM - 8405 AB - Because leptospirosis has been an important cause of morbidity in U.S. soldiers training in the Republic of Panama, we conducted a randomized, double-blind, placebo-controlled field trial during the fall of 1982 to determine whether doxycycline was an effective chemoprophylactic agent against this infection. Doxycycline (200 mg) or placebo was administered orally on a weekly basis and at the completion of training to 940 volunteers from two U.S. Army units deployed in Panama for approximately three weeks of jungle training. Twenty cases of leptospirosis occurred in the placebo group (an attack rate of 4.2 per cent), as compared with only one case in the doxycycline group (attack rate, 0.2 per cent, P less than 0.001), yielding an efficacy of 95.0 per cent. This study demonstrated the value of doxycycline as a prophylactic drug against leptospirosis. RO - M:RCT PMID- 6363930 CU - 95 SO - N Engl J Med 1984 Feb 23;310(8):497-500 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84105678 AU - Winter RJ AU - Richardson A AU - Lehner MJ AU - Hoffbrand BI TI - Lung abscess and reactive arthritis: rare complications of leptospirosis. LA - Eng MH - Arthritis/*etiology MH - Case Report MH - Human MH - Leptospirosis/*complications/radiography MH - Lung Abscess/*etiology/radiography MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 840323 DP - 1984 Feb 11 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 448-9 SB - A SB - M SB - X CY - ENGLAND IP - 6415 VI - 288 JC - B4X EM - 8405 PMID- 6419962 CU - 91 SO - Br Med J (Clin Res Ed) 1984 Feb 11;288(6415):448-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 84143081 AU - Blackmore DK AU - Schollum LM AU - Moriarty KM TI - The magnitude and duration of titres of leptospiral agglutinins in human sera. LA - Eng MH - Agglutination Tests MH - Agglutinins/*analysis MH - Food Inspection MH - Human MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/*immunology MH - Meat MH - Occupational Diseases/immunology MH - Support, Non-U.S. Gov't MH - Time Factors RN - 0 (Agglutinins) PT - JOURNAL ARTICLE DA - 840411 DP - 1984 Feb 8 IS - 0028-8446 TA - N Z Med J PG - 83-6 SB - M CY - NEW ZEALAND IP - 749 VI - 97 JC - OBQ AA - Author EM - 8406 AB - Sixty-nine meat inspectors with titres of leptospiral agglutinins ranging from 1:768 to 1:24, were re-bled and reexamined periodically over a period of 53 months. Some individuals maintained titres of 1:384 and 1:192 for at least 30 months and others with initial titres of 1:48 and 1:24 maintained such titres for 53 months. Only six, of 63 initially seronegative (less than 1:24) meat inspectors, seroconverted during the period of study. The magnitudes of titres at a single sampling from each of 162 people, with previous histories of medically confirmed leptospirosis, were analysed in relation to time elapsed since initial diagnosis. Some individuals had titres of 1:192 seven years after infection, while others had lower titres after more than 20 years. Conversely, 12% of the population was seronegative two years after infection. These results indicate that it is not possible, from the results of a leptospiral agglutination test, to estimate retrospectively the time at which infection may have occurred. In a small proportion of individuals recently affected by leptospirosis, it will not be possible to demonstrate a change in agglutinating titre. PMID- 6583569 CU - 91 SO - N Z Med J 1984 Feb 8;97(749):83-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 84231079 AU - Hancock GA AU - Wilks CR AU - Kotiw M AU - Allen JD TI - The long term efficacy of a hardjo-pomona vaccine in preventing leptospiruria in cattle exposed to natural challenge with Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacterial Vaccines/immunology/*therapeutic use MH - Bacteriuria/immunology/prevention & control/*veterinary MH - Cattle MH - Cattle Diseases/immunology/*prevention & control MH - Female MH - Leptospira interrogans/*immunology/isolation & purification MH - Vaccination/veterinary MH - Weil's Disease/immunology/prevention & control/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 840709 DP - 1984 Feb IS - 0005-0423 TA - Aust Vet J PG - 54-6 SB - M CY - AUSTRALIA IP - 2 VI - 61 JC - 9IE AA - Author EM - 8409 AB - The long term efficacy of a commercially prepared bivalent vaccine against Leptospira interrogans serovar hardjo and L. interrogans serovar pomona was evaluated in a group of 82 dairy heifers exposed to natural challenge with L. interrogans serovar hardjo for up to 55 weeks after calfhood vaccination. Nineteen heifers were vaccinated twice with a one-month interval, at calfhood (9 to 10 months). A further 18 heifers received a similar calfhood vaccination regimen plus a third injection at adulthood (22 to 23 months), while 19 heifers were vaccinated twice at adulthood only and finally 22 heifers were used as unvaccinated controls. At 55 weeks after calfhood vaccination and prior to adulthood vaccination, only 2.7% of the vaccinated heifers were found to have leptospiruria compared with 58.5% of the unvaccinated heifers (p less than 0.0001). Microscopic agglutination (MA) titres at the same time in the unvaccinated heifers ranged from 32 to 4096 while those vaccinated at calfhood ranged from 32 to 64. Adult vaccination of infected animals did not significantly reduce leptospiruria . Prior to adulthood vaccination, 9 of 19 heifers had leptospiruria , in comparison to 4 of 15 after adulthood vaccination. At the same sampling periods 15 of 22 controls had leptospiruria in comparison to 4 of 9 subsequently tested. PMID- 6732669 CU - 91 SO - Aust Vet J 1984 Feb;61(2):54-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 84161114 AU - Lindenbaum I AU - Eylan E AU - Shenberg E TI - Leptospirosis in Israel: a report of 14 cases caused by icterohaemorrhagiae serogroup (1968-82). LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Disease Outbreaks/*epidemiology MH - Epidemiologic Methods MH - Female MH - Hemagglutination Tests MH - Human MH - Israel MH - Leptospira/isolation & purification MH - Male MH - Middle Age MH - Rats MH - Weil's Disease/blood/*epidemiology/transmission PT - JOURNAL ARTICLE DA - 840516 DP - 1984 Feb IS - 0021-2180 TA - Isr J Med Sci PG - 123-9 SB - M SB - X CY - ISRAEL IP - 2 VI - 20 JC - GY0 AA - Author EM - 8407 AB - Fourteen cases of leptospirosis due to the Leptospira interrogans serogroup Icterohaemorrhagiae (Weil's disease) were serologically confirmed in the last 15 years. In two cases, Icterohaemorrhagiae was also isolated from the patients' blood. Both positive cultures were obtained in Korthof's medium by indirect passage through brain-heart infusion medium. One of the isolates was identified as serovar budapest, which has never been reported in Israel. In most of the cases, paradoxical cross-reactions with serovars of the Autumnalis, Hebdomadis and Canicola serogroups were observed in the early stages of the illness. In all cases, we suspected that the source of the infection was serovars of the Icterohaemorrhagiae serogroup shed in the urine of Rattus norvegicus rats. Thirteen of the affected persons were working and living in the Tel Aviv area, all in places not known to be Icterohaemorrhagiae endemic before 1968. One patient was working and living in the Hadera region. All patients were jaundiced, and one died. The illness was usually accompanied by pronounced and long-lasting elevation of blood bilirubin and urea levels. PMID- 6706536 CU - 88 SO - Isr J Med Sci 1984 Feb;20(2):123-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 84155735 AU - Prokopcakova H AU - Cislakova L TI - [Study of selected zoonoses in eastern Slovakia in recent times] LA - Slo MH - Czechoslovakia MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Occupational Diseases/*epidemiology MH - Ornithosis/*epidemiology MH - Tularemia/*epidemiology PT - JOURNAL ARTICLE DA - 840523 DP - 1984 Feb IS - 0006-9248 TA - Bratisl Lek Listy PG - 201-8 CY - CZECHOSLOVAKIA IP - 2 VI - 81 JC - B5N EM - 8407 PMID- 6704762 CU - 88 TT - Sledovanie vybranych zoonoz na uzemi Vychodoslovenskeho kraja za posledne obdobie. EA - A SO - Bratisl Lek Listy 1984 Feb;81(2):201-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84152391 AU - Barkay S AU - Garzozi H TI - Leptospirosis and uveitis. LA - Eng MH - Adolescence MH - Agricultural Workers' Diseases/diagnosis/*etiology MH - Case Report MH - Follow-Up Studies MH - Human MH - Israel MH - Leptospirosis/*complications/diagnosis MH - Male MH - Middle Age MH - Time Factors MH - Uveitis, Anterior/*etiology PT - JOURNAL ARTICLE DA - 840424 DP - 1984 Feb IS - 0003-4886 TA - Ann Ophthalmol PG - 164-8 SB - M CY - UNITED STATES IP - 2 VI - 16 JC - 5PA AA - Author EM - 8406 AB - In 1976 we presented seven patients with anterior uveitis due to leptospirosis with positive serological tests. During the years 1975 to 1977 we had the opportunity to observe a further 16 cases. In most of these cases the serological tests were positive for more than one leptospira serotype--in one case even five. In all the follow-up cases during a period of two to seven months, there was complete recovery. We suggest that leptospirosis is a possibility which should not be overlooked in the diagnosis of anterior uveitis, especially bilateral, in young males working in field irrigation and dairy workers in known endemic areas. PMID- 6538392 CU - 90 SO - Ann Ophthalmol 1984 Feb;16(2):164-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 84245214 AU - Kobayashi Y AU - Tamai T AU - Oyama T AU - Hasegawa H AU - Sada E AU - Kusaba T AU - Hamaji M TI - Characterization of monoclonal antibodies against etiological agents of Weil's disease. LA - Eng MH - Agglutination MH - Animal MH - Antibodies, Monoclonal/*immunology MH - Hybridomas/immunology MH - Leptospira interrogans/classification/*immunology MH - Mice MH - Species Specificity MH - Weil's Disease/*microbiology RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 840801 DP - 1984 IS - 0385-5600 TA - Microbiol Immunol PG - 359-70 SB - M CY - JAPAN IP - 3 VI - 28 JC - MX7 AA - Author EM - 8410 AB - Monoclonal antibodies against etiological agents of Weil's disease were produced by cell fusion technology. Twenty hybridomas were produced through the fusion of P3X63Ag8 .653 cells with spleen cells from BALB/c mice immunized against Leptospira interrogans serovar icterohaemorrhagiae RGA strain and serovar copenhageni Shiromizu and M20 strains. Reactivities of the antibodies produced by the hybridomas were determined by the microscopic agglutination test. Among the five hybridoma antibodies to the RGA strain, two reacted specifically to serovar icterohaemorrhagiae, two reacted to serovar icterohaemorrhagiae at a high titer and serovar copenhageni at a low titer, and one reacted to serovars icterohaemorrhagiae, copenhageni, pyrogens, and canicola. Of the ten hybridoma antibodies to the Shiromizu strain, one reacted specifically to serovar copenhageni, seven reacted to both serovars copenhageni and icterohaemorrhagiae at almost the same titer, and two exhibited intermediate properties. Of the five hybridoma antibodies to the M20 strain, three reacted to both serovars copenhageni and icterohaemorrhagiae at almost the same titer, one reacted to serovar copenhageni at a low titer and serovar icterohaemorrhagiae at a high titer, and one reacted to serovars copenhageni, icterohaemorrhagiae, and pyrogens. The results revealed that each serovar has its own antigen(s) and their common antigens. In addition, 20 strains of leptospires were recently isolated and tested with three monoclonal antibodies characterized by different reactivities. Twenty strains were clearly identified by their antibodies, i.e., 16 strains were identified as serovar icterohaemorrhagiae and three strains were identified as serovar copenhageni. The remaining strain, which was not agglutinated by three antibodies, was identified as serovar autumnalis by an agglutination test with immune rabbit sera. PMID- 6738384 CU - 91 SO - Microbiol Immunol 1984;28(3):359-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [80 medline neighbors] UI - 84245208 AU - Kojima T AU - Yanagihara Y AU - Mifuchi I TI - Characterization of inhibitor to leptospiral hemolysin present in bovine serum. LA - Eng MH - Animal MH - Blood/*metabolism MH - Cattle MH - Comparative Study MH - Erythrocyte Membrane/metabolism MH - Hemolysins/*metabolism MH - Hemolysis/drug effects MH - Leptospira/*metabolism MH - Phospholipase C/metabolism MH - Phospholipids/pharmacology RN - EC 3.1.4.3 (Phospholipase C) RN - 0 (Hemolysins) RN - 0 (Phospholipids) PT - JOURNAL ARTICLE DA - 840801 DP - 1984 IS - 0385-5600 TA - Microbiol Immunol PG - 291-302 SB - M CY - JAPAN IP - 3 VI - 28 JC - MX7 AA - Author EM - 8410 AB - Hemolysis by leptospiral hemolysin was strongly inhibited by bovine serum. The inhibitory activity was observed in the chloroform-methanol- soluble fraction of bovine serum. The inhibitor was eluted in a complex lipid fraction and was separated into two fractions (Fr. I and II) by silicic acid column chromatography. Fractions I and II inhibited approximately 75% and 95%, respectively, of hemolysis by leptospiral hemolysin. Fraction I was identified as phosphatidylethanolamine (PdE) by silica gel thin-layer chromatography (TLC). Two kinds of phospholipids (PLs) were detected in Fr. II by TLC. One was resistant to alkaline treatment and was identified as sphingomyelin (Spm), and the other was sensitive to such treatment and was identified as phosphatidylcholine (PdC). PLs, such as Spm, PdC, phosphatidylglycerol, PdE, phosphatidylserine and cardiolipin, inhibited hemolysis by leptospiral hemolysin, but phosphatidylinositol did not show any inhibitory activity. PLs lacking the amino group in the polar backbone of the molecules were more effective. From experiments using erythrocytes of various kinds of animals, it was revealed that the hemolytic sensitivity of mammalian erythrocytes to leptospiral hemolysin depended on the Spm content in the erythrocyte membrane. On the other hand, phospholipase C (PLase C) activity with Spm and PdC as substrates was detected in the culture supernatant of Leptospira. Therefore, leptospiral hemolysin was presumed to be PLase C, perhaps sphingomyelinase. The inhibitors of leptospiral hemolysin present in bovine serum were identified as PLs. PLs in bovine serum were suggested to function as inhibitors of the interaction between leptospiral hemolysin and the surface of the erythrocyte membrane. PMID- 6738381 CU - 91 SO - Microbiol Immunol 1984;28(3):291-302 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 84245088 AU - Rougier Y AU - Mailloux M AU - Bourget D AU - Davy R TI - [Immunologic survey on leptospirosis in the Marquesas Islands] LA - Fre MH - Adolescence MH - Adult MH - Antibodies, Bacterial/analysis MH - English Abstract MH - Health Surveys MH - Human MH - Leptospirosis/*epidemiology/immunology MH - Middle Age MH - Polynesia MH - Weil's Disease/epidemiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840808 DP - 1984 Jan-Mar IS - 0025-682X TA - Med Trop (Mars) PG - 23-5 SB - M CY - FRANCE IP - 1 VI - 44 JC - MHQ AA - Author EM - 8410 AB - Marquesas Islands, within the French Polynesian territory, are situated in the south hemisphere, near the Equator. They are volcanic islands, with a humid and hot climate, and high hygrometry . These islands are relatively isolated. Our sera were collected at the occasion of a blood test campaign: in Taiohae , 104 people, and Atuona , 149 people; they were between 17 and 57 years old. The results show that 45 people have antibodies against L. biflexa Patoc (17,8%). Among them, 24 have antibodies against icterohaemorrhagiae (9,5%). This is the evidence of the presence of leptospires in these islands. PMID- 6738334 CU - 91 TT - Enquete immunologique sur les leptospiroses aux Iles Marquises. EA - A SO - Med Trop (Mars) 1984 Jan-Mar;44(1):23-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 84218938 AU - Yanagihara Y AU - Kobayashi S AU - Mifuchi I TI - Sugar synthesis in Leptospira. I. Presence of glucosephosphate isomerase. LA - Eng MH - Citric Acid Cycle MH - Fructosephosphates/*metabolism MH - Gluconates/pharmacology MH - Glucosephosphate Isomerase/antagonists & inhibitors/*metabolism MH - Glucosephosphates/*metabolism MH - Hydrogen-Ion Concentration MH - Kinetics MH - Leptospira/*enzymology/metabolism MH - Temperature RN - EC 5.3.1.9 (Glucosephosphate Isomerase) RN - 0 (Fructosephosphates) RN - 0 (Gluconates) RN - 0 (Glucosephosphates) RN - 56-73-5 (Glucose-6-Phosphate) RN - 6814-87-5 (fructose-6-phosphate) RN - 921-62-0 (6-phosphogluconate) PT - JOURNAL ARTICLE DA - 840711 DP - 1984 IS - 0385-5600 TA - Microbiol Immunol PG - 189-96 SB - M CY - JAPAN IP - 2 VI - 28 JC - MX7 AA - Author EM - 8409 AB - The presence of glucosephosphate isomerase, one of the key enzymes in carbohydrate metabolism, was confirmed for the first time in the cell- free extract of Leptospira biflexa. The glucosephosphate isomerase of L. biflexa was heat-labile and its optimum pH was about 8.5. The enzyme showed an optimal temperature of about 45 C but was more stable at 30 C. Km value of the enzyme was 5.6 X 10(-3)M. The activity of the enzyme was inhibited by the inhibitor, 6-phosphogluconate. From this study, the presence of a metabolic pathway, the phosphogluconate pathway, other than non-oxidative pentose phosphate pathway presented by Baseman and Cox was suggested. PMID- 6727717 CU - 96 SO - Microbiol Immunol 1984;28(2):189-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 84173305 AU - Lins ZC AU - Lopes ML TI - Isolation of Leptospira from wild forest animals in Amazonian Brazil. LA - Eng MH - Animal MH - Animals/*microbiology MH - Animals, Wild/*microbiology MH - Brazil MH - Disease Reservoirs MH - Leptospira/*isolation & purification MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 840504 DP - 1984 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 124-6 SB - M CY - ENGLAND IP - 1 VI - 78 JC - WBU AA - Author EM - 8407 AB - The role of wild, forest animals as reservoirs of Leptospira was investigated in Para State, north Brazil. 696 animals were examined by culture of kidney tissue; isolates of serovar ballum were made from the rodent Proechimys sp. and the opossum Didelphis marsupialis; leptospires of the serogroups hebdomadis, grippotyphosa and cynopteri were isolated from the armadillo Dasypus novemcinctus, and as yet untyped leptospires were isolated from Proechimys and the procyonid carnivore Nasua nasua. Antibodies to serovars bataviae, butembo, canicola, castellonis, celledoni, grippotyphosa, panama, icterohaemorrhagiae and wolffi were demonstrated among 222 other animals examined by serological methods. PMID- 6710564 CU - 90 SO - Trans R Soc Trop Med Hyg 1984;78(1):124-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 84157795 AU - Jerrett IV AU - McOrist S AU - Waddington J AU - Browning JW AU - Malecki JC AU - McCausland IP TI - Diagnostic studies of the fetus, placenta and maternal blood from 265 bovine abortions. LA - Eng MH - Abortion, Septic/diagnosis/veterinary MH - Abortion, Veterinary/*diagnosis/etiology MH - Animal MH - Bovine Virus Diarrhea-Mucosal Disease/diagnosis MH - Campylobacter fetus MH - Campylobacter Infections/diagnosis/veterinary MH - Cattle MH - Cattle Diseases/*diagnosis/etiology MH - Female MH - Fetus/microbiology MH - Mycoses/diagnosis/veterinary MH - Placenta/microbiology MH - Placenta Diseases/diagnosis/veterinary MH - Pregnancy MH - Salmonella Infections, Animal/diagnosis PT - JOURNAL ARTICLE DA - 840524 DP - 1984 Jan IS - 0010-8901 TA - Cornell Vet PG - 8-20 SB - M CY - UNITED STATES IP - 1 VI - 74 JC - DRI AA - Author EM - 8407 AB - During 1981, the fetus, placenta and maternal serum were received from each of 265 bovine abortions. These specimens were examined using histopathological, histochemical, bacteriological, mycological, endocrinological, immunological, serological and virological techniques. The cause of abortion was identified in 98 (37%) cases. Of these diagnosed abortions 27 (28%) were due to infection with fungi, 17 (17%) to Salmonella spp, 11 (11%) to Campylobacter fetus and 10 (10%) to Corynebacterium pyogenes infection. Of the remaining 33 (34%) diagnosed abortions 8 were due to Leptospira sp, 5 due to protozoan (probably Sarcocystis) encephalitis and 20 due to miscellaneous bacterial infections (including Brucella abortus) and fetal deformities. Bovine virus diarrhoea virus was isolated in 5 (2%) abortions, however the significance of the isolations was not known. Infectious bovine rhinotracheitis virus and chlamydia were not identified as causal agents in any abortion. In 18 (7%) abortions no definite etiologic agent was identified despite pathological findings suggestive of infection. Fetal heart blood serology and immunoglobulin values were not reliable indicators of infectious abortion. Of the remaining 149 (56%) abortions, 17% had high maternal serum cortisol levels and twin fetuses occurred in 9%. PMID- 6705541 CU - 90 SO - Cornell Vet 1984 Jan;74(1):8-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 84149421 AU - Soboleva GL AU - Malakhov IuA AU - Belousov VI AU - Shmarikova TV TI - [Effect storage temperature on the biological properties of Leptospira] LA - Rus MH - Agglutination Tests MH - Animal MH - English Abstract MH - Hamsters MH - Leptospira/*pathogenicity MH - Lethal Dose 50 MH - Mesocricetus MH - *Preservation, Biological MH - *Temperature MH - Time Factors MH - Virulence PT - JOURNAL ARTICLE DA - 840412 DP - 1984 Jan IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 38-42 SB - M CY - USSR IP - 1 JC - Y9O AA - Author EM - 8406 AB - No essential changes occurred in the morphology, viability and agglutinability of 212 Leptospira strains belonging to 20 serological groups during 2-year storage in ampoules at temperatures of -60 to -70 degrees C, and 18 to 24 degrees C. After storage lasting 3 and 4 years viability was retained, respectively, by 95.75 and 78.5% of the strains stored at a temperature of -60 to -70 degrees C and by 90.9 and 70% of the strains stored at room temperature. During 4 years of storage at room temperature the agglutinability of the strains decreased 2-8 times. Most of the strains retained their virulence unchanged for 2 years at a temperature of -60 to -70 degrees C. PMID- 6702359 CU - 90 TT - Vliianie temperatury khraneniia na biologicheskie svoistva leptospir. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1984 Jan;(1):38-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 84143315 AU - Gong YH TI - Leptospiral cerebral arteritis: report of 4 autopsy cases. LA - Eng MH - Arteritis/*pathology MH - Cerebral Arteries/pathology MH - Cerebral Artery Diseases/*pathology MH - Child MH - Child, Preschool MH - Human MH - Leptospirosis/*pathology PT - JOURNAL ARTICLE DA - 840402 DP - 1984 IS - 0253-3316 TA - Acta Acad Med Wuhan PG - 44-9 CY - CHINA IP - 1 VI - 4 JC - ODF EM - 8406 PMID- 6700927 SO - Acta Acad Med Wuhan 1984;4(1):44-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 84132609 AU - Grigor'ev VE TI - [Leptospirosis] LA - Rus MH - Animal MH - Disease Vectors MH - Human MH - Leptospirosis/epidemiology/*transmission MH - USSR PT - JOURNAL ARTICLE DA - 840425 DP - 1984 Jan IS - 0014-9772 TA - Feldsher Akush PG - 12-4 SB - N CY - USSR IP - 1 VI - 49 JC - EVA EM - 8406 PMID- 6559703 CU - 88 LI - N TT - Leptospirozy. SO - Feldsher Akush 1984 Jan;49(1):12-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85163224 AU - Madle-Samardzija N AU - Mikic B AU - Zecevic M TI - [2 case reports of hepatorenal syndrome caused by Leptospira icterohaemorrhagiae] LA - Scr MH - Adult MH - Case Report MH - Human MH - Kidney Failure, Acute/*etiology MH - Male MH - Middle Age MH - Syndrome MH - Weil's Disease/*complications/genetics PT - JOURNAL ARTICLE DA - 850513 DP - 1984 IS - 0025-8105 TA - Med Pregl PG - 419-21 CY - YUGOSLAVIA IP - 9-10 VI - 37 JC - M8U EM - 8507 PMID- 6530988 CU - 90 TT - Povodom dva slucaja hepatorenalnog sindroma uzrokovanog leptospirom ikterohemoragije. SO - Med Pregl 1984;37(9-10):419-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [214 medline neighbors] UI - 85066759 AU - Everard CO AU - Edwards CN AU - Webb GB AU - White HS AU - Nicholson GD TI - The prevalence of severe leptospirosis among humans on Barbados. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agglutination Tests MH - Barbados MH - Child MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology/microbiology/mortality MH - Male MH - Middle Age MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 841226 DP - 1984 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 596-603 SB - M CY - ENGLAND IP - 5 VI - 78 JC - WBU AA - Author EM - 8503 AB - Leptospirosis was confirmed by the Leptospira Laboratory in 138 hospital patients on Barbados between early November 1979 and the end of 1982 (annual average 43.6 cases). These were the great majority of severe cases occurring on the island during that time. The crude incidence rate ranged between 15 and 23 per 100,000 population per year (average 17.6). 26 of the patients died (15 males, 11 females), giving an over-all case fatality rate of 18.8%, and an average of 8.2 deaths per year. 68% of all cases were in males. The highest percentages of cases were in males aged 20 to 24 and females aged 55 to 59, but the incidence of the disease in both sexes increased with age up to 60 years. Previous figures recorded on the island by the Ministry of Health for 1975-79 were considerably lower, with a mean of 23.6 cases per year and a crude annual incidence of 9.5 per 100,000. 15 of the patients died (13 males, 2 females), giving an over-all case fatality rate of 12.7% and an average of 3 deaths per year. 74% of all cases were in males. The highest percentages of cases were in the 20 to 29 and 50 to 59 year age groups for males and females, respectively, i.e., similar to those in the present series. In both sexes the incidence of leptospirosis increased with age up to 60 years.(ABSTRACT TRUNCATED AT 250 WORDS) PMID- 6506150 CU - 88 SO - Trans R Soc Trop Med Hyg 1984;78(5):596-603 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 85064652 AU - Anusz Z TI - [Brucellosis and other zoonoses 1982. Human brucellosis] LA - Pol MH - Abattoirs MH - Animal MH - Brucellosis/*epidemiology MH - Brucellosis, Bovine/epidemiology MH - Cattle MH - Comparative Study MH - Erysipeloid/epidemiology MH - Female MH - Human MH - Leptospirosis/epidemiology MH - Male MH - Occupational Diseases/epidemiology MH - Poland MH - Seasons MH - Toxoplasmosis/epidemiology MH - Veterinary Medicine MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 850118 DP - 1984 IS - 0033-2100 TA - Przegl Epidemiol PG - 205-11 CY - POLAND IP - 2 VI - 38 JC - Q8T EM - 8503 PMID- 6505239 CU - 88 TT - Bruceloza i inne choroby odzwierzece--1982 rok. Bruceloza ludzi. SO - Przegl Epidemiol 1984;38(2):205-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [92 medline neighbors] UI - 85060573 AU - Kojima T AU - Yanagihara Y AU - Mifuchi I TI - Detoxification of tween for the cultivation of Leptospira. LA - Eng MH - Comparative Study MH - *Culture Media MH - Leptospira canicola/*growth & development MH - Polysorbates/*isolation & purification/toxicity RN - 0 (Culture Media) RN - 0 (Polysorbates) PT - JOURNAL ARTICLE DA - 850114 DP - 1984 IS - 0385-5600 TA - Microbiol Immunol PG - 949-54 SB - M CY - JAPAN IP - 8 VI - 28 JC - MX7 EM - 8503 PMID- 6503745 CU - 92 SO - Microbiol Immunol 1984;28(8):949-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 85035894 AU - Yanagihara Y AU - Taniyama T AU - Misaki H AU - Suzuki Y AU - Matsumoto M AU - Mifuchi I TI - Phospholipases of Leptospira. I. Presence of phospholipase A1 and lysophospholipase in Leptospira biflexa. LA - Eng MH - Comparative Study MH - Heat MH - Hydrogen-Ion Concentration MH - Leptospira/*enzymology MH - Lysophospholipase/metabolism MH - Phosphatidylethanolamines MH - Phospholipases/*metabolism MH - Phospholipases A/metabolism RN - EC 3.1.- (Phospholipases) RN - EC 3.1.1.- (Phospholipases A) RN - EC 3.1.1.5 (Lysophospholipase) RN - 0 (Phosphatidylethanolamines) PT - JOURNAL ARTICLE DA - 841218 DP - 1984 IS - 0385-5600 TA - Microbiol Immunol PG - 747-56 SB - M CY - JAPAN IP - 7 VI - 28 JC - MX7 AA - Author EM - 8502 AB - The hydrolysis of phosphatidylethanolamine, phosphatidylcholine, lysophosphatidylcholine, and trioleoylglycerol by Leptospira biflexa strain Urawa was studied in vitro. Phospholipase A1 was identified by the formation of 32P- and 14C-labeled lysoderivatives from 32P- phosphatidylcholine, 32P-phosphatidylethanolamine, or 1-acyl-2-[1- 14C]oleoyl-sn-glycero-3-phosphorylcholine. Phospholipase A1 activity was independent of lipase in the microorganism since 14C-labeled trioleoylglycerol was scarcely attacked under the same conditions in which the phospholipids were hydrolyzed. Lysophospholipase activity was also demonstrated using 32P- and non-labeled lysophosphatidylcholine. The activity of phospholipase A1 was found in a broad range of pH but no optimal pH was determined. The pH optimum of lysophospholipase was 8.0. Both enzymes were labile to heat. Phospholipase C activity, however, could not be detected because no radioactive di- and monoacylglycerol was found in the experiment with 1-acyl-2-[1-14C]- oleoyl-sn-glycero-3-phosphorylcholine as the substrate. It was inferred that phosphatidylethanolamine, which was the major component of phospholipids in leptospirae, was hydrolyzed serially by phospholipase A (A1 and/or A2?) and lysophospholipase to glycerophosphorylethanolamine via 2-acyl-type-lyso-derivative as one metabolic pathway of the substrate. PMID- 6493072 CU - 92 SO - Microbiol Immunol 1984;28(7):747-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 85017803 AU - Ratnam S AU - Sundararaj T AU - Subramanian S AU - Madanagopalan N AU - Jayanthi V TI - Humoral and cell-mediated immune responses to leptospires in different human cases. LA - Eng MH - Antibody Formation MH - Cell Migration Inhibition MH - Human MH - Immunity, Cellular MH - Leptospirosis/*immunology MH - Leukocytes/immunology PT - JOURNAL ARTICLE DA - 841121 DP - 1984 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 539-42 SB - M CY - ENGLAND IP - 4 VI - 78 JC - WBU AA - Author EM - 8501 AB - Humoral and cell-mediated immune responses (CMI) to leptospirosis were studied in different groups of human patients. These included clinically suspected cases of leptospirosis, patients with jaundice (HBsAg negative), cases of pyrexia of unknown origin (PUC) (Widal and blood culture negative for typhoid) and healthy blood donors. Humoral immune response was evaluated with nine live strains representing different serogroups of leptospires and CMI with lysates of four strains. The study showed that the CMI appeared earlier than the humoral response which might be useful in the early detection of the disease. As in the humoral immune response, cross reactions to different leptospires were also seen in CMI response. PMID- 6485058 SO - Trans R Soc Trop Med Hyg 1984;78(4):539-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 84294938 AU - Yanagihara Y AU - Kamisango K AU - Yasuda S AU - Kobayashi S AU - Mifuchi I AU - Azuma I AU - Yamamura Y AU - Johnson RC TI - Chemical compositions of cell walls and polysaccharide fractions of spirochetes. LA - Eng MH - Carbohydrates/analysis MH - Cell Wall/*analysis MH - Comparative Study MH - Peptidoglycan/analysis MH - Polysaccharides, Bacterial/*analysis MH - Species Specificity MH - Spirochaetaceae/*analysis MH - Support, Non-U.S. Gov't RN - 0 (Polysaccharides, Bacterial) PT - JOURNAL ARTICLE DA - 840928 DP - 1984 IS - 0385-5600 TA - Microbiol Immunol PG - 535-44 SB - M CY - JAPAN IP - 5 VI - 28 JC - MX7 AA - Author EM - 8412 AB - Cellular polysaccharide fractions of various representative members of genera of the family Spirochaetaceae were obtained by the ammonium hydroxide extraction method. The sugar composition of the polysaccharide preparations was complex and many kinds of sugars such as rhamnose, fucose, ribose, xylose, mannose, galactose, and glucose were detected in all of the spirochetes tested. Of particular interest was the presence of 4-O-methylmannose as a constituent polysaccharide in members of the genus Leptospira. This sugar was not detected in the polysaccharides of Spirochaeta, Borrelia, and Treponema. The chemical compositions of cell wall fractions were also examined. 4-O- Methylmannose was detected in the cell wall polysaccharides of the genus Leptospira but not in cell walls prepared from the Spirochaeta, Borrelia, and Treponema. The diaminopimelic acid present in cell wall peptidoglycans of the genus Leptospira was meso-diaminopimelic acid (A2pm). The molar ratios of alanine, glutamic acid, A2pm, glycine, muramic acid, and glucosamine in leptospiral cell walls were found to be approximately 2:1:1:1:1:1. In contrast to the Leptospira, the peptidoglycans of genera Spirochaeta, Borrelia, and Treponema contained ornithine (Orn) but not A2pm. Since 4-O-methylmannose and A2pm were found in the cell wall fractions of genus Leptospira but not in Spirochaeta, Borrelia, or Treponema, it was suggested that the chemical compositions of the cell wall might become an important criterion for the chemotaxonomy of Spirochaetales. PMID- 6472134 CU - 91 SO - Microbiol Immunol 1984;28(5):535-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 84294937 AU - Yanagihara Y AU - Kobayashi S AU - Mifuchi I TI - Sugar synthesis in Leptospira. II. Presence of glyoxylate cycle enzymes. LA - Eng MH - Carbohydrates/*biosynthesis MH - Comparative Study MH - Glyoxylates/metabolism MH - Hydrogen-Ion Concentration MH - Isocitrate Lyase/*metabolism MH - Ketoacid-Lyases/*metabolism MH - Leptospira/*metabolism MH - Malate Synthase/*metabolism RN - EC 4.1.3. (Ketoacid-Lyases) RN - EC 4.1.3.1 (Isocitrate Lyase) RN - EC 4.1.3.2 (Malate Synthase) RN - 0 (Glyoxylates) PT - JOURNAL ARTICLE DA - 840928 DP - 1984 IS - 0385-5600 TA - Microbiol Immunol PG - 529-34 SB - M CY - JAPAN IP - 5 VI - 28 JC - MX7 AA - Author EM - 8412 AB - The presence and some properties of the key enzymes of the glyoxylate cycle, isocitrate lyase (threo-Ds-isocitrate glyoxylate-lyase, EC 4.1.3.1) and malate synthase (L-malate glyoxylate-lyase (CoA- acetylating) EC 4.1.3.2), were investigated in Leptospira biflexa. Isocitrate lyase activity was found for the first time in the organism. The enzyme was induced by ethanol but not by acetate. The optimum pH was 6.8. The activity was inhibited by phosphoenolpyruvate, a specific inhibitor of isocitrate lyase. The optimum pH of malate synthase of L. biflexa was about 8.5. The Km value for glyoxylate was 3.0 X 10(-3) M and the activity was inhibited by glycolate, the inhibitor. The results strongly suggested the presence of a glyoxylate cycle in Leptospira. The possibility that the glyoxylate cycle plays an essential role in the synthesis of sugars, amino acids and other cellular components as an anaplerotic pathway of the tricarboxylic acid cycle in Leptospira was discussed. PMID- 6472133 CU - 92 SO - Microbiol Immunol 1984;28(5):529-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 84275471 AU - Jeandel P AU - Raoult D AU - Rougier Y AU - Auger C AU - Mailloux M TI - Late positive blood cultures in leptospiroses (report of four cases). LA - Eng MH - Aged MH - Blood/microbiology MH - Case Report MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*microbiology MH - Male MH - Middle Age MH - Time Factors PT - JOURNAL ARTICLE DA - 840918 DP - 1984 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 143-5 SB - M CY - ENGLAND IP - 2 VI - 78 JC - WBU AA - Author EM - 8411 AB - Leptospirosis in Tahiti was studied during 1981. 42 cases were detected by positive blood cultures grown in Stuart's medium. The present paper describes the isolation of leptospira from the blood of four cases 30 days after the date of onset. PMID- 6464102 CU - 90 SO - Trans R Soc Trop Med Hyg 1984;78(2):143-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 85244210 AU - Corridori S AU - Fornasari PM AU - Trespi G TI - [Plasma exchange in infectious pathology] LA - Ita MH - Hepatitis B/*etiology MH - Hepatitis C/*etiology MH - Hepatitis, Viral, Human/*etiology/therapy MH - Human MH - Leptospirosis/therapy MH - Plasma Exchange/*adverse effects MH - Shock, Septic/therapy PT - JOURNAL ARTICLE DA - 850801 DP - 1984 IS - 0035-6204 TA - Riv Emoter Immunoematol PG - 124-9 CY - ITALY IP - 2 VI - 31 JC - TJ5 EM - 8510 PMID- 6443035 CU - 91 TT - Il plasmia exchange nellapatologia infettiva. SO - Riv Emoter Immunoematol 1984;31(2):124-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 84248890 AU - Juszczyk J AU - Lewkowicz H AU - Adamek J AU - Furmaniuk J AU - Klemczak K AU - Szkaradkiewicz A AU - Kiczka W TI - [Occurrence of Listeria , Bedsonia, Leptospira and Brucella antibodies in workers on animal husbandry farms in Wielkopolska] LA - Pol MH - Adult MH - Animal MH - *Animal Husbandry MH - Antibodies, Bacterial/*isolation & purification MH - Brucella abortus/*immunology MH - Cattle MH - Chlamydia/*immunology MH - English Abstract MH - Female MH - Human MH - Leptospira/*immunology MH - Listeria monocytogenes/*immunology MH - Male MH - Middle Age MH - *Occupational Medicine MH - Poland MH - Sheep MH - Swine RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840807 DP - 1984 IS - 0033-2100 TA - Przegl Epidemiol PG - 11-8 CY - POLAND IP - 1 VI - 38 JC - Q8T EM - 8410 PMID- 6429736 CU - 91 TT - Wystepowanie przeciwcial listeriozowych, bedsoniazowych, leptospirozowych i brucelozowych u pracownikow wielkopolskich gospodarstw hodowli zarodowej. EA - A SO - Przegl Epidemiol 1984;38(1):11-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 90173419 AU - Seric K AU - Cengic F AU - Zvizdic S TI - [Distribution of leptospirosis infection in patients clinically suspect for leptospirosis] LA - Scr MH - Agglutination Tests MH - Antigens, Bacterial/*analysis MH - English Abstract MH - Human MH - Incidence MH - Leptospira/classification MH - Leptospirosis/*diagnosis/epidemiology MH - Serotyping MH - Yugoslavia/epidemiology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 900411 DP - 1984 IS - 0025-8083 TA - Med Arh PG - 147-51 CY - YUGOSLAVIA IP - 4 VI - 38 JC - LNY EM - 9006 PMID- 6400961 CU - 91 NP - X TT - Prilog ispitivanju rasirenosti leptospiroznih infekcija kod bolesnika sa klinickom sumnjom na leptospirozu. EA - A SO - Med Arh 1984;38(4):147-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 85060726 AU - Mazzonelli J AU - Dorta de Mazzonelli GT AU - Mailloux M TI - Determination of the heat labile point of leptospiral antigens. LA - Eng MH - Agglutination Tests MH - *Antigens, Bacterial MH - Comparative Study MH - Heat MH - Immunosorbent Techniques MH - Leptospira/*immunology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 850118 DP - 1984 IS - 0300-8584 TA - Med Microbiol Immunol (Berl) PG - 141-3 SB - M CY - GERMANY, WEST IP - 3 VI - 173 JC - M58 AA - Author EM - 8503 AB - Pyrogenes Salinem antigen, prepared at different temperatures, is used to adsorb heterologous anti-Chiffon and anti-Pomona sera, and the lability point of the antigen is determined by the macroagglutination test. Results show that the effect of this thermolabile antigen starts to be destroyed after 10 min at 60 degrees C with anti-Pomona serum and at 65 degrees C with anti-Chiffon serum. The method of measurement is not sensitive enough and the lability point would probably be lower than that obtained in these tests. The authors consider a more accurate method to be the combined use of the adsorption and microagglutination tests, with comparative titration of an heterologous antiserum. PMID- 6390111 CU - 91 SO - Med Microbiol Immunol (Berl) 1984;173(3):141-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 85045421 AU - Harrison AP Jr TI - The acidophilic thiobacilli and other acidophilic bacteria that share their habitat. LA - Eng MH - Bacteria/*physiology MH - Culture Media MH - Hydrogen-Ion Concentration MH - Iron/metabolism MH - Leptospira/metabolism MH - Species Specificity MH - Sulfur/metabolism MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Thiobacillus/*physiology MH - Thiobacillus thiooxidans/metabolism RN - 0 (Culture Media) RN - 7439-89-6 (Iron) RN - 7704-34-9 (Sulfur) PT - JOURNAL ARTICLE PT - REVIEW DA - 841219 DP - 1984 IS - 0066-4227 TA - Annu Rev Microbiol PG - 265-92 SB - M CY - UNITED STATES VI - 38 JC - 6DV EM - 8502 RF - 95 PMID- 6388492 CU - 91 SO - Annu Rev Microbiol 1984;38:265-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 85045417 AU - Harwood CS AU - Canale-Parola E TI - Ecology of spirochetes. LA - Eng MH - Aerobiosis MH - Anaerobiosis MH - Animal MH - Antigens, Bacterial/analysis MH - Bacteriophages/physiology MH - Cell Movement MH - Chemotaxis MH - *Ecology MH - Human MH - Leptospira/physiology MH - Mouth/microbiology MH - Plasmids MH - Species Specificity MH - Spirochaeta/physiology MH - Spirochaetales/classification/isolation & purification/*physiology/pathogenicity MH - Spirochaetales Infections/microbiology MH - Support, U.S. Gov't, P.H.S. RN - 0 (Antigens, Bacterial) RN - 0 (Plasmids) PT - JOURNAL ARTICLE PT - REVIEW ID - AI-17737/AI/NIAID DA - 841219 DP - 1984 IS - 0066-4227 TA - Annu Rev Microbiol PG - 161-92 SB - M CY - UNITED STATES VI - 38 JC - 6DV EM - 8502 RF - 209 PMID- 6388490 CU - 96 SO - Annu Rev Microbiol 1984;38:161-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 85089246 AU - Winearls CG AU - Chan L AU - Coghlan JD AU - Ledingham JG AU - Oliver DO TI - Acute renal failure due to leptospirosis: clinical features and outcome in six cases. LA - Eng MH - Adult MH - Aged MH - Atrial Fibrillation/complications MH - Bilirubin/blood MH - Female MH - Gastrointestinal Hemorrhage/complications MH - Hemodialysis MH - Human MH - Kidney Failure, Acute/*etiology/therapy MH - Leptospirosis/blood/*complications MH - Leukocyte Count MH - Male MH - Middle Age MH - Platelet Count MH - Thrombocytopenia/complications RN - 635-65-4 (Bilirubin) PT - JOURNAL ARTICLE DA - 850125 DP - 1984 Autumn IS - 0033-5622 TA - Q J Med PG - 487-95 SB - M CY - ENGLAND IP - 212 VI - 53 JC - QKZ AA - Author EM - 8504 AB - Six cases of severe leptospiral infection with renal failure are described. Five of the six patients had acute oliguric renal failure requiring dialysis. Renal function recovered over three weeks and by two months all patients had plasma creatinine levels less than 200 mumol/litre. The initial diagnosis of leptospirosis depended on clinical and epidemiological features because serological confirmation was not possible during the first week of the illness. All the patients had either high risk occupations or a history of exposure to external sources of infection. All had fever, myalgia, jaundice and muscle tenderness. Although bilirubin levels were high (greater than 350 mumol/litre in five) the elevations of aspartate transaminase and alkaline phosphatase levels, and prolongations of prothrombin times were relatively slight. Thrombocytopenia occurred in five of the six cases. Leptospira complement fixation tests were weakly positive or negative on admission in five cases but rose to significant levels subsequently. Penicillin treatment resulted in Jarisch-Herxheimer reactions in three cases. The important complications were: upper gastro-intestinal haemorrhage (five cases), thrombocytopenia less than 30 000 platelets/mm3 (four cases), atrial fibrillation (three cases), drowsiness with asterixis (four cases). All six patients were seriously ill and required intensive supportive therapy. All survived. PMID- 6334867 CU - 89 SO - Q J Med 1984 Autumn;53(212):487-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84130280 AU - Prokopcakova H TI - [Study of the ecology of Leptospira in old natural foci in eastern Slovakia] LA - Slo MH - Animal MH - Cattle/*microbiology MH - Czechoslovakia MH - *Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira/*isolation & purification MH - Rodentia/*microbiology PT - JOURNAL ARTICLE DA - 840409 DP - 1984 Jan IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 9-15 CY - CZECHOSLOVAKIA IP - 1 VI - 33 JC - CSH EM - 8406 PMID- 6230168 CU - 92 TT - Sledovanie ekologie leptospir v starych prirodnych ohniskach Vychodoslovenskeho kraja. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1984 Jan;33(1):9-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 85059218 AU - Pupkevich-Diamant IaS AU - Nisnevich EB TI - [Activity of dehydrogenases and their isoenzymes in the blood of patients with leptospirosis and viral hepatitis] LA - Rus MH - Alcohol Oxidoreductases/*blood MH - English Abstract MH - Hepatitis B/*enzymology MH - Human MH - Isoenzymes/*blood MH - Leptospirosis/*enzymology MH - Weil's Disease/enzymology RN - EC 1.1 (Alcohol Oxidoreductases) RN - 0 (Isoenzymes) PT - JOURNAL ARTICLE DA - 850122 DP - 1984 IS - 0023-6748 TA - Lab Delo PG - 589-93 CY - USSR IP - 10 JC - KYU EM - 8503 PMID- 6209451 CU - 95 TT - Aktivnost' degidrogenaz i ikh izofermentov v krovi bol'nykh leptospirozom i virusnym gepatitom. EA - A SO - Lab Delo 1984;(10):589-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84260874 AU - Cai Z TI - [Cerebral arteritis due to leptospirosis] LA - Chi MH - Adolescence MH - Adult MH - Arteritis/diagnosis/*etiology MH - Cerebrovascular Disorders/diagnosis/*etiology MH - Child MH - Child, Preschool MH - Diagnosis, Differential MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*complications MH - Male PT - JOURNAL ARTICLE DA - 840907 DP - 1983 Dec IS - 0412-4057 TA - Chung Hua Shen Ching Ching Shen Ko Tsa Chih PG - 356-8 CY - CHINA IP - 6 VI - 16 JC - D7Y EM - 8411 PMID- 6678215 EA - A SO - Chung Hua Shen Ching Ching Shen Ko Tsa Chih 1983 Dec;16(6):356-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84172410 AU - Bunnag T AU - Potha U AU - Thirachandra S AU - Impand P TI - Leptospirosis in man and rodents in North and Northeast Thailand. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Antibodies/analysis MH - Child MH - Child, Preschool MH - Disease Reservoirs MH - Female MH - Human MH - Infant MH - Leptospirosis/*epidemiology/immunology/veterinary MH - Male MH - Middle Age MH - Retrospective Studies MH - Rodent Diseases/*epidemiology MH - Rural Population MH - Thailand RN - 0 (Antibodies) PT - JOURNAL ARTICLE DA - 840522 DP - 1983 Dec IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 481-7 SB - M CY - THAILAND IP - 4 VI - 14 JC - UVN AA - Author EM - 8407 AB - A seroepidemiological study of leptospirosis in man and rodents in the North and Northeast Thailand revealed that 0.27% of the rural people from three different ecologic areas were positive. The positivity rate has dropped dramatically when compared to a previous survey (28%). Of 1,135 wild rodents studied, 42 of 365 (11.5%) B. indica and 50 of 676 (7.4%) R. rattus were serologically positive. Others were negative. Only two of 157 R. rattus had positive cultures in which L. javanica and L. autumnalis were isolated. The study shows that wild rats are naturally implicated in human disease as a common reservoir and that the yearly rat eradication campaigns attributed as one of the effective factors in a major reduction of disease to a level of non significant public health hazard. PMID- 6673123 CU - 91 SO - Southeast Asian J Trop Med Public Health 1983 Dec;14(4):481-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84156828 AU - Rioche M AU - Mailloux M TI - [Current status of leptospirosis in Morocco (1979-1981)] LA - Fre MH - Agglutination Tests MH - Animal MH - Disease Vectors MH - English Abstract MH - Human MH - Leptospira/classification MH - *Leptospirosis/epidemiology/immunology/parasitology/*transmission MH - Morocco MH - Rats/parasitology MH - Serotyping PT - JOURNAL ARTICLE DA - 840507 DP - 1983 Dec IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 750-4 SB - M CY - FRANCE IP - 5 Pt 2 VI - 76 JC - C4G AA - Author EM - 8407 AB - Leptospiroses in Morocco have been studied from 1979 to 1981. In man, L. icterohaemorrhagiae is the most frequently diagnosed serotype. The highest incidence of positive diagnoses is found in Fes-Meknes area. Leptospirosis is a severe disease: 1 out of 3 patients is hospitalized in Intensive Care Unit. Rat is an essential carrier of germs in Casablanca. PMID- 6671269 CU - 88 TT - Etat actuel de la leptospirose au Maroc (1979-1981). EA - A SO - Bull Soc Pathol Exot Filiales 1983 Dec;76(5 Pt 2):750-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84156827 AU - Mollaret HH AU - Mailloux M AU - Debarbat F TI - [Leptospirosis on the Island of Reunion. III. Epidemiologic study] LA - Fre MH - Animal MH - Disease Vectors MH - Dog Diseases/parasitology MH - Dogs/parasitology MH - English Abstract MH - Human MH - Indian Ocean Islands MH - Leptospira/classification MH - Leptospirosis/*epidemiology/parasitology/transmission MH - Rodent Diseases/parasitology MH - Serotyping MH - Water Microbiology PT - JOURNAL ARTICLE DA - 840507 DP - 1983 Dec IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 744-9 SB - M CY - FRANCE IP - 5 Pt 2 VI - 76 JC - C4G AA - Author EM - 8407 AB - In the island of Reunion, rodents and wild dogs can be carriers of leptospires. Aquatic environmental plays an important part. Human contamination is associated with water and sugar cane. Animals are infected by numerous serogroups. PMID- 6671268 CU - 88 TT - Leptospiroses a la Reunion. III. Etude epidemiologique. EA - A SO - Bull Soc Pathol Exot Filiales 1983 Dec;76(5 Pt 2):744-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84156826 AU - Debarbat F AU - Mollaret HH AU - Mailloux M TI - [Leptospirosis on the Island of Reunion. II. Animal leptospiroses] LA - Fre MH - Animal MH - Cattle/parasitology MH - Cattle Diseases/parasitology MH - Diagnosis, Differential MH - English Abstract MH - Geography MH - Horse Diseases/parasitology MH - Horses/parasitology MH - Indian Ocean Islands MH - Leptospirosis/classification/diagnosis/parasitology/*veterinary MH - Rain MH - Serotyping PT - JOURNAL ARTICLE DA - 840507 DP - 1983 Dec IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 736-43 SB - M CY - FRANCE IP - 5 Pt 2 VI - 76 JC - C4G AA - Author EM - 8407 AB - Bovine leptospirosis is a typical form in the island of Reunion. It appears during the second part of the rain season. The clinical picture of equine leptospirosis is acute hepatonephritis. About 10 serogroups are found in bovines, with greater frequency for Sejroe and Hebdomadis. In horses, the prevailing serogroups are Autumnalis, Ballum, Icterohaemorrhagiae, Australis, Grippotyphosa. PMID- 6671267 CU - 90 TT - Leptospiroses a la Reunion. II. Leptospiroses animales. EA - A SO - Bull Soc Pathol Exot Filiales 1983 Dec;76(5 Pt 2):736-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 84156825 AU - Mailloux M AU - Debarbat F AU - Mollaret HH TI - [Leptospirosis on the Island of Reunion. I. Human leptospiroses] LA - Fre MH - Adult MH - Age Factors MH - English Abstract MH - Female MH - Geography MH - Human MH - Indian Ocean Islands MH - Leptospirosis/diagnosis/*epidemiology/immunology MH - Male MH - Occupations MH - Rain MH - Rural Population MH - Serotyping MH - Sex Factors MH - Urban Population MH - Weil's Disease/diagnosis/epidemiology/immunology PT - JOURNAL ARTICLE DA - 840507 DP - 1983 Dec IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 729-35 SB - M CY - FRANCE IP - 5 Pt 2 VI - 76 JC - C4G AA - Author EM - 8407 AB - Human leptospiroses in the island of Reunion have a common point: they are severe diseases. Approximately 50 to 60 cases are biologically diagnosed every year. The number of cases is correlated with rainfall. The predominating serogroup is Icterohaemorrhagiae, followed by Canicola, Grippotyphosa and Australis. PMID- 6671266 CU - 90 TT - Leptospiroses a la Reunion. I. Leptospiroses humaines. EA - A SO - Bull Soc Pathol Exot Filiales 1983 Dec;76(5 Pt 2):729-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 84148623 AU - Zeigermakher GA AU - Chernokozinskii AA TI - [Clinical and epidemiological characteristics of leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Female MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Ukraine MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 840425 DP - 1983 Dec IS - 0049-6804 TA - Vrach Delo PG - 100-3 CY - USSR IP - 12 JC - XLS EM - 8406 PMID- 6670225 CU - 88 TT - O kliniko-epidemiologicheskoi kharakteristike leptospiroza. SO - Vrach Delo 1983 Dec;(12):100-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84103138 AU - Oie S AU - Hironaga K AU - Koshiro A AU - Konishi H AU - Yoshii Z TI - In vitro susceptibilities of five Leptospira strains to 16 antimicrobial agents. LA - Eng MH - Antibiotics/*pharmacology MH - Leptospira/*drug effects MH - Microbial Sensitivity Tests RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 840224 DP - 1983 Dec IS - 0066-4804 TA - Antimicrob Agents Chemother PG - 905-8 SB - M CY - UNITED STATES IP - 6 VI - 24 JC - 6HK AA - Author EM - 8404 AB - The in vitro activities of 16 antibiotics against five serovar strains of the genus Leptospira were determined. Five of the antibiotics (ampicillin, cefmetazole, moxalactam, ceftizoxime, and cefotaxime) exhibited a lower minimal inhibitory concentration than did penicillin G. In tests for minimal bactericidal concentration, ceftizoxime and cefotaxime were found to be more effective than penicillin G, streptomycin, tetracycline, ampicillin, and cefmetazole. PMID- 6660857 CU - 91 SO - Antimicrob Agents Chemother 1983 Dec;24(6):905-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 84102563 AU - Bey RF AU - Johnson RC TI - Leptospiral vaccines: immunogenicity of protein-free medium cultivated whole cell bacterins in swine. LA - Eng MH - Adjuvants, Immunologic MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Bacterial Vaccines/*immunology MH - Culture Media MH - Female MH - Leptospira/growth & development/*immunology MH - Leptospirosis/prevention & control/veterinary MH - Male MH - Support, U.S. Gov't, P.H.S. MH - Swine/*immunology MH - Swine Diseases/prevention & control MH - Vaccination/veterinary RN - 0 (Adjuvants, Immunologic) RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (Culture Media) PT - JOURNAL ARTICLE ID - AI-06589/AI/NIAID DA - 840214 DP - 1983 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2299-301 SB - M CY - UNITED STATES IP - 12 VI - 44 JC - 40C AA - Author EM - 8404 AB - Swine serologically negative for anti-Leptospira antibodies were given 2 doses of a pentavalent vaccine (3 weeks between doses) prepared from Leptospira serovars canicola, icterohaemorrhagiae, hardjo, pomona, and grip-potyphosa (0.2 mg/serovar/dose). Leptospires used for vaccinal production were cultivated in a protein-free medium or in a bovine albumin-containing medium. All vaccinated swine had demonstrable antibody titers within 1 week of the initial vaccination. Peak microscopic agglutination titers were between 256 and 1,024 after the 2nd vaccinal dose was given. After challenge exposure with serovar canicola, control swine had titers of at least 13,653 and the vaccinated swine had titers of 3,403 to 8,192, depending on the vaccine. Leptospiremia and kidney infections were not detected in any canicola Moulton immunized swine, but did appear in control swine. The Al(OH)3 adjuvant had no obvious influence of any of the vaccinal titers. PMID- 6660619 CU - 96 SO - Am J Vet Res 1983 Dec;44(12):2299-301 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 84102552 AU - Thiermann AB TI - Bovine leptospirosis: bacteriologic versus serologic diagnosis of cows at slaughter. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*diagnosis MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Kidney/microbiology MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/diagnosis/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840214 DP - 1983 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2244-5 SB - M CY - UNITED STATES IP - 12 VI - 44 JC - 40C AA - Author EM - 8404 AB - Blood for serologic examination and kidneys for bacteriologic cultural examination were collected from 204 cows slaughtered in an Iowa packing plant during August to October 1981. By the microscopic agglutination test on the 200 serum samples which were collected, 29 (14.5%) were positive--22 samples (10.8%) had agglutinin titers to hardjo, 4 (2%) to pomona, and 5 (2.5%) to other serovars. With the enzyme-linked immunosorbent assay, 79 samples (39.5%) were positive--53 (26.5%) to hardjo and 36 (18%) to pomona. Leptospires were isolated from 13 (6.4%) of the kidneys (n = 204) examined. Characterization indicated that 7 isolates were hardjo; 3, grippotyphosa; and 2, pomona (1 isolate was lost during first subculture). Three of the hardjo isolates and 1 of the grippotyphosa isolates were obtained from cows that were seronegative by the microscopic agglutination test. PMID- 6660611 CU - 91 SO - Am J Vet Res 1983 Dec;44(12):2244-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 84063481 AU - Demers RY AU - Thiermann A AU - Demers P AU - Frank R TI - Exposure to Leptospira icterohaemorrhagiae in inner-city and suburban children: a serologic comparison. LA - Eng MH - Antibodies, Bacterial/*analysis MH - Child, Preschool MH - Comparative Study MH - Human MH - Infant MH - Leptospira interrogans/*immunology MH - Michigan MH - Suburban Population MH - Urban Population MH - Weil's Disease/*immunology/transmission RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840127 DP - 1983 Dec IS - 0094-3509 TA - J Fam Pract PG - 1007-11 SB - A SB - M CY - UNITED STATES IP - 6 VI - 17 JC - I4L AA - Author EM - 8403 AB - This study explores the exposure of urban children to the spirochete Leptospira icterohaemorrhagiae. This organism is carried by 90 percent of the rats in Detroit. It is felt that these rats are a potential vehicle for childhood exposure to this organism. Strain-specific tests were performed comparing antibody levels in sera of inner-city (exposed) and suburban (unexposed) children. Study and control groups, numbering 124 and 113, respectively, showed significant serologic differences, with urban children having higher antibody titers. The findings are indicative of differential exposure rates and suggest that actual cases of leptospirosis may be present, yet undiagnosed. PMID- 6644249 CU - 91 SO - J Fam Pract 1983 Dec;17(6):1007-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 84211418 AU - Minette HP TI - Leptospirosis in poikilothermic vertebrates. A review. LA - Eng MH - Amphibia/*microbiology MH - Animal MH - Disease Reservoirs MH - Fish Diseases/microbiology MH - Fishes/microbiology MH - Leptospira/classification/isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Mice MH - Reptiles/*microbiology MH - Serotyping PT - JOURNAL ARTICLE PT - REVIEW DA - 840625 DP - 1983 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 111-21 SB - M CY - TAIWAN IP - 2 VI - 10 JC - GTK AA - Author EM - 8409 AB - Autochthanous leptospirosis does occur in the poikilothermic vertebrates, as evidenced by positive serological reactions and by the isolation of pathogenic leptospiral serovars. These findings in aquatic members of this group are of special importance in view of the increased worldwide interest in aquaculture farming. Since 1975, 24 of the 101 (23.7%) reported human cases of leptospirosis in Hawaii have been associated with aquaculture industries (taro farms, prawn farms and watercress farms). Antibody synthesis and persistence in these animals is variable, and seems to depend to some extent on environmental temperatures. Some members of the group apparently lack the capacity for immunological memory, experience a considerable delay (lag-phase) in antibody formation, demonstrate the "paradoxical reaction" found in other animals, and can maintain living pathogenic leptospirae in their organs in the absence of detectable antibody utilizing our present serologic methods. For these reasons, serological studies as the sole source of evidence for leptospiral infection cannot be recommended. The immunologic mechanism of lower vertebrates is not known, some studies suggesting that there may be more than one antibody system active in these animals, especially the turtles, and further investigation at the cellular and subcellular levels is indicated. The growth temperatures and nutritional requirements of leptospirae isolated from other than warm-blooded animals is also poorly understood. Some knowledge has been contributed by various investigators in recent years, but much more work needs to be done in studying the nutritional and metabolic requirements of leptospirae isolated from all sources, including the various fauna resident in and around the fresh water streams and ponds. RF - 74 PMID- 6373645 CU - 90 SO - Int J Zoonoses 1983 Dec;10(2):111-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84127774 AU - Ellis TM AU - Robertson GM AU - Hustas L AU - Kirby M TI - Detection of leptospires in tissue using an immunoperoxidase staining procedure. LA - Eng MH - Animal MH - *Immunoenzyme Techniques MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Sheep/microbiology MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 840228 DP - 1983 Dec IS - 0005-0423 TA - Aust Vet J PG - 364-7 SB - M CY - AUSTRALIA IP - 12 VI - 60 JC - 9IE AA - Author EM - 8405 AB - An immunoperoxidase technique for the localisation of leptospires in sections of formalin fixed paraffin embedded kidney tissue is described. The procedure utilises a two-layered antibody sandwich with rabbit anti-leptospiral immunoglobin. Using antiserum to specific leptospiral serovars the presence and distribution of specific serovar in the tissue could be determined. The technique was also used to detect leptospires of given serovars in smears made from infected tissues and fluids. There was good correlation between culture results and results of the immunoperoxidase staining method on kidneys infected with leptospires. The diagnostic possibilities of the technique on formalin fixed tissue specimens are discussed. PMID- 6365066 CU - 90 SO - Aust Vet J 1983 Dec;60(12):364-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 84061351 AU - Clark RK AU - Jessup DA AU - Hird DW AU - Ruppanner R AU - Meyer ME TI - Serologic survey of California wild hogs for antibodies against selected zoonotic disease agents. LA - Eng MH - Animal MH - Animals/*immunology MH - Animals, Wild/*immunology MH - Antibodies/*analysis MH - Bacterial Infections/immunology/veterinary MH - Brucella/immunology MH - California MH - Comparative Study MH - Coxiella/immunology MH - Female MH - Herpesvirus 1, Suid/immunology MH - Leptospira interrogans/immunology MH - Male MH - Mycobacterium avium/immunology MH - Pseudorabies/immunology MH - Swine/immunology MH - Swine Diseases/*immunology MH - Toxoplasma/immunology MH - Toxoplasmosis, Animal/immunology MH - Tuberculosis/immunology/veterinary MH - Yersinia pestis/immunology RN - 0 (Antibodies) PT - JOURNAL ARTICLE DA - 840127 DP - 1983 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1248-51 SB - M CY - UNITED STATES IP - 11 VI - 183 JC - HAV AA - Author EM - 8403 AB - Blood samples were collected from trapped or hunter-killed wild hogs (Sus scrofa) in 4 areas of California. Sera were tested for antibodies against 7 zoonotic disease agents. Antibodies against Brucella sp were detected in 21 (15%) of 136 samples. Antibodies against Coxiella burnetii were found in 50% of the collected samples (67 of 135 tested). Of the 135 wild hogs screened for pseudorabies virus, 4 (3%) were seropositive. Leptospira interrogans antibodies were discovered in 118 (87%) of the 136 samples tested. Of the 130 samples screened for antibodies against Mycobacterium avium complex, 111 (85%) were seropositive. Antibodies against Toxoplasma gondii were detected in 17 (13%) of 135 wild hogs. Antibodies against Yersinia pestis were found in 9 (15%) of 59 sera tested. PMID- 6315659 CU - 93 SO - J Am Vet Med Assoc 1983 Dec 1;183(11):1248-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 84165704 AU - Tsuchimoto M AU - Kida H AU - Yanagawa R AU - Inui S TI - Leptospira interrogans serovar hardjo infection in cows of Hokkaido, Japan--serological evidence. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*diagnosis MH - Epitopes MH - Female MH - Japan MH - Leptospira interrogans/*immunology MH - Weil's Disease/diagnosis/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 840523 DP - 1983 Dec IS - 0021-5295 TA - Nippon Juigaku Zasshi PG - 811-4 CY - JAPAN IP - 6 VI - 45 JC - KRJ EM - 8407 PMID- 6200638 CU - 95 SO - Nippon Juigaku Zasshi 1983 Dec;45(6):811-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84054095 TI - Leptospirosis in man, British Isles, 1982. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agricultural Workers' Diseases/epidemiology MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Outbreaks/epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - Female MH - Great Britain MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Male MH - Middle Age MH - Zoonoses/etiology PT - JOURNAL ARTICLE DA - 840107 DP - 1983 Nov 5 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 1365-6 SB - A SB - M SB - X CY - ENGLAND IP - 6402 VI - 287 JC - B4X EM - 8403 PMID- 6416416 CU - 91 NI - A SO - Br Med J (Clin Res Ed) 1983 Nov 5;287(6402):1365-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 84207273 AU - Yang XZ TI - [Distribution of serotypes of Leptospira in the southeast region of Guizhou Province] LA - Chi MH - Animal MH - China MH - Disease Vectors MH - English Abstract MH - Human MH - Leptospira/*isolation & purification MH - Muridae/microbiology MH - Serotyping MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 840710 DP - 1983 Nov IS - 0253-9624 TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 349-51 CY - CHINA IP - 6 VI - 17 JC - D74 EM - 8409 PMID- 6675985 EA - A SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1983 Nov;17(6):349-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 84077494 AU - Raoult D AU - Jeandel P AU - Mailloux M AU - Rougier Y TI - Thrombocytopenia and renal failure in leptospirosis. LA - Eng MH - Human MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications MH - Polynesia MH - Retrospective Studies MH - Thrombocytopenia/*etiology PT - JOURNAL ARTICLE DA - 840126 DP - 1983 Nov IS - 0002-9637 TA - Am J Trop Med Hyg PG - 1464 SB - A SB - M CY - UNITED STATES IP - 6 VI - 32 JC - 3ZQ AA - Author EM - 8403 AB - In a retrospective study of 60 cases of leptospirosis, the association of thrombocytopenia and acute renal failure as previously reported was confirmed. However, increased mortality, in our experience, was not associated with either thrombocytopenia or acute renal failure. PMID- 6650748 CU - 84 SO - Am J Trop Med Hyg 1983 Nov;32(6):1464 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 84062228 AU - Jennings BR AU - Mincer H AU - Turner J AU - Baselski V AU - Kelly RT TI - Use of avidin-biotinylated horseradish peroxidase complex for visualization of spirochetes. LA - Eng MH - *Avidin MH - *Bacteriological Techniques MH - Horseradish Peroxidase MH - *Ovalbumin/analogs & derivatives MH - *Spirochaetales MH - Support, Non-U.S. Gov't RN - EC 1.11.1.- (Horseradish Peroxidase) RN - 1405-69-2 (Avidin) RN - 9006-59-1 (Ovalbumin) PT - JOURNAL ARTICLE DA - 840107 DP - 1983 Nov IS - 0095-1137 TA - J Clin Microbiol PG - 1250-1 SB - M CY - UNITED STATES IP - 5 VI - 18 JC - HSH AA - Author EM - 8403 AB - The use of avidin-biotinylated peroxidase as a simple technique for light microscopic visualization of spirochetes is described. The three major genera of spirochetes--Treponema, Borrelia, and Leptospira--were stained with the avidin complex. PMID- 6358252 CU - 90 SO - J Clin Microbiol 1983 Nov;18(5):1250-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 84096740 AU - Morales Sandino M AU - Lopez Cortes L AU - Garces Mera M AU - Sanchez Roman J TI - [Leptospirosis in our environment. Study of 17 cases] LA - Spa MH - English Abstract MH - Female MH - Human MH - Leptospirosis/complications/diagnosis/*epidemiology MH - Male MH - Spain PT - JOURNAL ARTICLE DA - 840224 DP - 1983 Oct 31 IS - 0014-2565 TA - Rev Clin Esp PG - 125-9 CY - SPAIN IP - 2 VI - 171 JC - RNL EM - 8404 PMID- 6658091 CU - 88 TT - Leptospirosis en nuestro medio. Estudio de 17 casos. EA - A SO - Rev Clin Esp 1983 Oct 31;171(2):125-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84031973 AU - Thiermann AB TI - Leptospirosis immunization [letter] LA - Eng MH - Animal MH - Bacterial Vaccines/standards MH - Cat Diseases/*prevention & control MH - Cats MH - Dog Diseases/*prevention & control MH - Dogs MH - Leptospira/immunology MH - Leptospirosis/*prevention & control MH - Vaccination/*veterinary RN - 0 (Bacterial Vaccines) PT - LETTER DA - 831220 DP - 1983 Oct 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 838-9 SB - M CY - UNITED STATES IP - 8 VI - 183 JC - HAV EM - 8402 PMID- 6629995 CU - 91 SO - J Am Vet Med Assoc 1983 Oct 15;183(8):838-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84279393 AU - Nicolescu M AU - Andreescu N TI - Attempts for determining the infecting serogroup by means of agglutinin absorption from the leptospirosis patients' sera. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Human MH - Leptospira/*classification/immunology MH - Leptospira canicola/classification MH - Leptospira interrogans/classification MH - Leptospirosis/*microbiology MH - Serotyping MH - Weil's Disease/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840917 DP - 1983 Oct-Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 249-54 CY - ROMANIA IP - 4 VI - 42 JC - 8EM EM - 8411 PMID- 6678568 CU - 91 SO - Arch Roum Pathol Exp Microbiol 1983 Oct-Dec;42(4):249-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84057654 AU - Ellis WA AU - O'Brien JJ AU - Cassells JA AU - Montgomery J TI - Leptospiral infection in horses in Northern Ireland: serological and microbiological findings. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/immunology MH - Female MH - Horse Diseases/immunology/*microbiology MH - Horses MH - Kidney/microbiology MH - Leptospira/classification/immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - Northern Ireland MH - Serotyping RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 840127 DP - 1983 Oct IS - 0425-1644 TA - Equine Vet J PG - 317-20 SB - M CY - ENGLAND IP - 4 VI - 15 JC - EJ9 AA - Author EM - 8403 AB - Thirteen strains of pathogenic leptospires were isolated from 12 of 91 horses; seven strains belonged to the Australis serogroup (serotype bratislava) with three, two and one strains belonging to the Icterohaemorrhagiae, Hebdomadis (serotype hardjo) and Autumnalis serogroups respectively. Using leptospires isolated from horses and others representing the known parasitic Leptospira serogroups, a sample of 650 mares' sera was tested for agglutinating antibodies. Antibodies were found in 89.1 per cent of sera. The predominant reaction was to serotype bratislava, strain S/1334/79, isolated in this study, antibodies to which were detected in 81.8 per cent of sera. It is suggested that serotype bratislava may be adapted to, and maintained by, the horse population in Northern Ireland. PMID- 6641678 CU - 91 SO - Equine Vet J 1983 Oct;15(4):317-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 84050480 AU - Songer JG AU - Chilelli CJ AU - Reed RE AU - Trautman RJ TI - Leptospirosis in rodents from an arid environment. LA - Eng MH - Animal MH - Animals, Domestic MH - Antigens, Bacterial/analysis MH - Arizona MH - *Climate MH - Housing, Animal MH - Kidney/microbiology MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Rodent Diseases/*epidemiology/microbiology MH - Rodentia MH - Species Specificity MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 831220 DP - 1983 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1973-6 SB - M CY - UNITED STATES IP - 10 VI - 44 JC - 40C AA - Author EM - 8402 AB - Rodents (n = 358) were trapped from 6 locations in Arizona, including 2 dairies, 2 swine raising operations, and 2 areas where domestic animal access was limited. Isolates of Leptospira interrogans serovar ballum were obtained from 3 house mice (Mus musculus) trapped in dairies. Leptospira were seen in silver-stained kidney sections of 10.4% of the rodents. The usefulness of serologic data in detecting leptospiral infection in these rodents was uncertain because so few animals yielded isolates that valid comparisons of culture positives to serologic positives were not possible. Titers greater than or equal to 1:160 were obtained to serovars autumnalis, ballum, bratislava, canicola, grippotyphosa, hardjo, icterohaemorrhagiae, and pomona. Nearly 60% of the rodents had microscopic lesions in kidneys, including 20 of 34 (59%) of those in which leptospira were seen. PMID- 6638656 CU - 91 SO - Am J Vet Res 1983 Oct;44(10):1973-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84137155 AU - Kobayashi Y AU - Tamai T AU - Oyama T AU - Hasegawa H AU - Shiroguchi T AU - Sada E AU - Kusaba T AU - Hamaji M TI - [Identification of Leptospira responsible for Weil's disease by monoclonal antibody] LA - Jpn MH - Animal MH - Antibodies, Monoclonal/*analysis MH - English Abstract MH - Human MH - Leptospira/*classification/immunology MH - Leptospira interrogans/classification/immunology MH - Mice MH - Weil's Disease/immunology/*microbiology RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 840425 DP - 1983 Oct IS - 0387-5911 TA - Kansenshogaku Zasshi PG - 846-52 CY - JAPAN IP - 10 VI - 57 JC - IJR EM - 8406 PMID- 6421947 CU - 91 EA - A SO - Kansenshogaku Zasshi 1983 Oct;57(10):846-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [97 medline neighbors] UI - 84100286 AU - Golubev MV AU - Litvin VIu TI - [Mechanism of the maintenance of the infective capacity of soil in a natural focus of leptospirosis] LA - Rus MH - Animal MH - Carrier State/microbiology/urine MH - *Disease Reservoirs MH - Disease Vectors MH - English Abstract MH - Leptospirosis/*transmission/urine MH - Microtinae/microbiology MH - *Soil Microbiology MH - Time Factors PT - JOURNAL ARTICLE DA - 840214 DP - 1983 Oct IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 43-6 SB - M CY - USSR IP - 10 JC - Y9O AA - Author EM - 8404 AB - The radioisotope modeling of the processes of the release of leptospires into the soil and the daily measurements of the radiation doses revealed that leptospires were regularly added by individual carriers, as well as by a group of carriers, into common infected spots on the territory of the infection focus. The frequency with which leptospires were added by a carrier into different infected spots varied: during 7 days leptospires were added 7 times and more into 16% of the spots, up to 5 times into 49% of the spots; into 35% of the spots no leptospires were added. The microscopic and bacteriological methods of investigation demonstrated that the regular release of leptospires into the infected spots resulted in maintaining the concentration of leptospires at such spots and their infective capacity. The number and distribution of these spots determined the stability of the epizootic potential of the territory. PMID- 6362291 CU - 90 TT - O mekhanizme podderzhaniia zarazhaiushchei sposobnosti pochvy v prirodnom ochage leptospiroza. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Oct;(10):43-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84057655 AU - Ellis WA AU - Bryson DG AU - O'Brien JJ AU - Neill SD TI - Leptospiral infection in aborted equine foetuses. LA - Eng MH - *Abortion, Veterinary MH - Animal MH - Antibodies, Bacterial/analysis MH - Female MH - Fetal Diseases/diagnosis/*veterinary MH - Fluorescent Antibody Technique MH - Horse Diseases/*diagnosis MH - Horses MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - Pregnancy RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840127 DP - 1983 Oct IS - 0425-1644 TA - Equine Vet J PG - 321-4 SB - M CY - ENGLAND IP - 4 VI - 15 JC - EJ9 AA - Author EM - 8403 AB - During an investigation of equine abortion, leptospiral infection was demonstrated in nine out of 22 foetuses examined by immunofluorescence and culture. Strains belonging to four serogroups (Australis, Pomona, Hebdomadis and Icterohaemorrhagiae) were isolated. The age of leptospira infected foetuses ranged from six months to term. PMID- 6357776 CU - 91 SO - Equine Vet J 1983 Oct;15(4):321-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [49 medline neighbors] UI - 84065051 AU - Zarnke RL TI - Serologic survey for selected microbial pathogens in Alaskan wildlife. LA - Eng MH - Alaska MH - Animal MH - Animals/*immunology MH - Animals, Wild/*immunology MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/analysis MH - Artiodactyla/immunology MH - Bears/immunology MH - Brucella/*immunology MH - Coxiella/*immunology MH - Deer/immunology MH - Leptospira/*immunology MH - Reindeer/immunology MH - Sheep/immunology MH - Species Specificity MH - Support, U.S. Gov't, Non-P.H.S. MH - Viruses/*immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 840127 DP - 1983 Oct IS - 0090-3558 TA - J Wildl Dis PG - 324-9 SB - M CY - UNITED STATES IP - 4 VI - 19 JC - KEM AA - Author EM - 8403 AB - Antibodies to Brucella spp. were detected in sera of seven of 67 (10%) caribou (Rangifer tarandus), one of 39 (3%) moose (Alces alces), and six of 122 (5%) grizzly bears (Ursus arctos). Antibodies to Leptospira spp. were found in sera of one of 61 (2%) caribou, one of 37 (3%) moose, six of 122 (5%) grizzly bears, and one of 28 (4%) black bears (Ursus americanus). Antibodies to contagious ecthyma virus were detected in sera of seven of 17 (41%) Dall sheep (Ovis dalli) and five of 53 (10%) caribou. Antibodies to epizootic hemorrhagic disease virus were found in sera of eight of 17 (47%) Dall sheep and two of 39 (6%) moose. Infectious bovine rhinotracheitis virus antibodies were detected in sera of six of 67 (9%) caribou. Bovine viral diarrhea virus antibodies were found in sera of two of 67 (3%) caribou. Parainfluenza 3 virus antibodies were detected in sera of 14 of 21 (67%) bison (Bison bison). Antibodies to Q fever rickettsia were found in sera of 12 of 15 (80%) Dall sheep. No evidence of prior exposure to bluetongue virus was found in Dall sheep, caribou, moose, or bison sera. PMID- 6139490 CU - 94 SO - J Wildl Dis 1983 Oct;19(4):324-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 83298552 AU - Avery TL TI - Leptospirosis and mental illness [letter] LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*complications MH - Male MH - Mental Disorders/*complications PT - LETTER DA - 831021 DP - 1983 Sep 14 IS - 0028-8446 TA - N Z Med J PG - 701 SB - M CY - NEW ZEALAND IP - 739 VI - 96 JC - OBQ EM - 8312 PMID- 6577345 CU - 91 SO - N Z Med J 1983 Sep 14;96(739):701 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [86 medline neighbors] UI - 84046554 AU - Hathaway SC AU - Little TW AU - Headlam SA AU - Stevens AE TI - Infection of free-living carnivores with leptospires of the Australis serogroup. LA - Eng MH - Animal MH - Carnivora/*microbiology MH - Foxes/microbiology MH - Leptospira/classification MH - Leptospirosis/microbiology/*veterinary MH - Mink/microbiology MH - Serotyping/*veterinary PT - JOURNAL ARTICLE DA - 831217 DP - 1983 Sep 10 IS - 0042-4900 TA - Vet Rec PG - 233-5 SB - M CY - ENGLAND IP - 11 VI - 113 JC - XBS AA - Author EM - 8402 AB - Leptospires belonging to the Australis serogroup were isolated from badgers (Meles meles), mink (Lutreola lutreola) and a fox (Vulpes vulpes). Most isolates were identified by cross-agglutination absorption as serovar muenchen but one isolate from a fox from Surrey and one isolate from a badger from Northern Ireland were identified as serovar bratislava. Maintenance of serovar muenchen by a wide range of free-living species is an ecological condition unique to Great Britain. PMID- 6636479 SO - Vet Rec 1983 Sep 10;113(11):233-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84207251 TI - [Isolation of a new serotype of Leptospira from Bombina orientalis (Boulenger)] LA - Chi MH - Animal MH - Anura/*microbiology MH - English Abstract MH - Guinea Pigs MH - Leptospira/classification/*isolation & purification/pathogenicity MH - Serotyping PT - JOURNAL ARTICLE DA - 840709 DP - 1983 Sep IS - 0253-9624 TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 283-4 CY - CHINA IP - 5 VI - 17 JC - D74 EM - 8409 PMID- 6675967 NI - A EA - A SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1983 Sep;17(5):283-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 84075888 AU - Ellis WA AU - Hovind-Hougen K AU - Moller S AU - Birch-Andresen A TI - Morphological changes upon subculturing of freshly isolated strains of Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Hamsters MH - Leptospira interrogans/growth & development/*ultrastructure MH - Microscopy, Electron MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 840107 DP - 1983 Sep TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 323-35 SB - M CY - GERMANY, WEST IP - 2-3 VI - 255 JC - Y5N AA - Author EM - 8403 AB - The morphology of freshly isolated strains of Leptospira interrogans serovar hardjo was studied by electron microscopy and was compared to that of established laboratory strains of the same serovar and to some other serovars within the Hebdomadis serogroup. Changes in the morphology of freshly isolated strains of serovar hardjo were observed when the isolates were subcultured in the laboratory. Cells of strains subcultured more than 20 times were longer and had longer wavelengths, and electron lucent inclusions were observed less frequently than in cells of strains subcultured less than 10 times. Upon hamster passage, cells subcultured 40 and 50 times became more similar to cells of low passage number than to those of the inoculate. The results are discussed and the importance of environmental factors for the growth of leptospires is emphasized. PMID- 6649981 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1983 Sep;255(2-3):323-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84060792 AU - Collins BJ AU - Nelson JK TI - Hyperosmolar non-ketotic diabetic coma precipitated by leptospira hebdomadis infection. LA - Eng MH - Animal MH - Case Report MH - Cattle MH - Diabetes Mellitus, Non-Insulin-Dependent/*complications MH - Diabetic Coma/*etiology MH - Human MH - Leptospirosis/*complications/diagnosis/drug therapy MH - Male MH - Middle Age MH - Northern Ireland MH - Penicillin G/therapeutic use MH - Support, Non-U.S. Gov't RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 840107 DP - 1983 Sep IS - 0021-1265 TA - Ir J Med Sci PG - 360-1 CY - IRELAND IP - 9 VI - 152 JC - GXB EM - 8403 PMID- 6642964 SO - Ir J Med Sci 1983 Sep;152(9):360-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 84025506 AU - Hathaway SC AU - Little TW AU - Wrathall AE TI - Experimental infection of pregnant gilts with leptospires isolated from British wildlife. II. Clinical, bacteriological and pathological aspects of infection. LA - Eng MH - Abortion, Veterinary/pathology MH - Animal MH - Animals, Wild MH - Female MH - Kidney Diseases/pathology/veterinary MH - Leptospirosis/diagnosis/pathology/*veterinary MH - Male MH - Pregnancy MH - Pregnancy Complications, Infectious/*veterinary MH - Serodiagnosis MH - Swine MH - Swine Diseases/*diagnosis/pathology PT - JOURNAL ARTICLE DA - 831220 DP - 1983 Sep-Oct IS - 0007-1935 TA - Br Vet J PG - 404-14 CY - ENGLAND IP - 5 VI - 139 JC - B5C EM - 8402 PMID- 6626930 CU - 90 SO - Br Vet J 1983 Sep-Oct;139(5):404-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 84025505 AU - Hathaway SC AU - Little TW AU - Wrathall AE TI - Experimental infection of pregnant gilts with leptospires isolated from British wildlife. I. Serological response to infection. LA - Eng MH - Animal MH - Animals, Wild MH - Cross Reactions MH - Female MH - Leptospirosis/immunology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/immunology/*veterinary MH - Serodiagnosis MH - Swine MH - Swine Diseases/*immunology PT - JOURNAL ARTICLE DA - 831220 DP - 1983 Sep-Oct IS - 0007-1935 TA - Br Vet J PG - 393-403 CY - ENGLAND IP - 5 VI - 139 JC - B5C EM - 8402 PMID- 6626929 CU - 90 SO - Br Vet J 1983 Sep-Oct;139(5):393-403 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 84022046 AU - Songer JG AU - Chilelli CJ AU - Marshall MM AU - Noon TH AU - Meyer R TI - Serologic survey for leptospirosis in Arizona beef cattle in 1981. LA - Eng MH - Animal MH - Arizona MH - Cattle MH - Cattle Diseases/*epidemiology/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 831123 DP - 1983 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1763-4 SB - M CY - UNITED STATES IP - 9 VI - 44 JC - 40C AA - Author EM - 8401 AB - Sera from 1,215 beef cattle in Arizona were evaluated by leptospiral microscopic agglutination test in 1981. Over 25% had agglutinins to greater than or equal to 1 of 5 serovars of Leptospira interrogans used as antigens (canicola, grippotyphosa, hardjo, icterohaemorrhagiae, and pomona) at a titer of greater than or equal to 1:100, and 8.2% had titers of greater than or equal to 1:400 to greater than or equal to 1 serovars. The most common serovar to which reactions were detected was hardjo; agglutinins were detected at titers of greater than or equal to 1:100 in 14.3% and of greater than or equal to 1:400 in 5.5%. Cross reactions were rare at serum dilutions greater than or equal to 1:100 (2%) and extremely rare at greater than or equal to 1:400 (0.7%). Because vaccination with leptospiral bacterins is seldom practiced in Arizona beef cattle, a titer of greater than or equal to 1:100 may be useful in estimating incidence and prevalence of the disease and as an aid to diagnosis of leptospirosis. PMID- 6625331 CU - 88 SO - Am J Vet Res 1983 Sep;44(9):1763-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 84075887 AU - Adler B AU - Faine S TI - Species- and genus-specific antigens in Leptospira, revealed by monoclonal antibodies and enzyme immunoassay. LA - Eng MH - Antibodies, Monoclonal MH - Antigens, Bacterial/*classification/immunology MH - Immunoenzyme Techniques MH - Leptospira/classification/*immunology MH - Leptospira interrogans/classification/*immunology MH - Serotyping MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 840107 DP - 1983 Sep TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 317-22 SB - M CY - GERMANY, WEST IP - 2-3 VI - 255 JC - Y5N AA - Author EM - 8403 AB - Mouse antisera to Leptospira interrogans serovar pomona or L. biflexa serovar patoc agglutinated homologous leptospires but not leptospires of serovars from any heterologous serogroup tested. When tested by enzyme immunoassay (EIA), pomona and patoc antisera reacted with all serovars tested from L. interrogans, L. biflexa or L. illini species. A non-agglutinating hybridoma-derived monoclonal antibody reacted by EIA only with serovars of the pathogenic L. interrogans species but not with L. biflexa nor L. illini. The results demonstrated the presence of both genus and species specific non-agglutinating leptospiral antigens which could be detected only by EIA. PMID- 6359778 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1983 Sep;255(2-3):317-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 84019178 AU - Giles N AU - Hathaway SC AU - Stevens AE TI - Isolation of Leptospira interrogans serovar hardjo from a viable premature calf. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Animals, Newborn MH - Antibodies, Bacterial/analysis MH - Cattle/*microbiology MH - Cattle Diseases/*etiology MH - Female MH - Great Britain MH - Kidney/microbiology MH - Lactation Disorders/etiology/*veterinary MH - Leptospira interrogans/immunology/*isolation & purification MH - Pregnancy MH - Urine/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 831123 DP - 1983 Aug 20 IS - 0042-4900 TA - Vet Rec PG - 174-6 SB - M CY - ENGLAND IP - 8 VI - 113 JC - XBS AA - Author EM - 8401 AB - A severe outbreak of agalactia in a dairy herd of 80 cows was followed by six premature calvings and an abortion. Serological and bacteriological studies identified Leptospira hardjo as the probable cause. A leptospire isolated from the kidney of a premature calf killed seven weeks post partum was identified as hardjo and it is probable that this infection was acquired in utero. The maintenance of such an infection for a considerable period after birth has not been previously described and may play a role in the transmission of hardjo to susceptible in-contact animals. PMID- 6623882 CU - 91 SO - Vet Rec 1983 Aug 20;113(8):174-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 84019167 AU - Hathaway SC AU - Ellis WA AU - Little TW AU - Stevens AE AU - Ferguson HW TI - Leptospira interrogans serovar hardjo in pigs: a new host-parasite relationship in the United Kingdom. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Female MH - Great Britain MH - Leptospira interrogans/classification/*isolation & purification MH - Pregnancy MH - Serotyping MH - Swine/*microbiology MH - Swine Diseases/*microbiology MH - Weil's Disease/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 831123 DP - 1983 Aug 13 IS - 0042-4900 TA - Vet Rec PG - 153-4 SB - M CY - ENGLAND IP - 7 VI - 113 JC - XBS AA - Author EM - 8401 AB - The first isolations of Leptospira interrogans serovar hardjo from pigs are recorded. Evidence that hardjo may be a sporadic cause of porcine reproductive disease is presented. PMID- 6623873 SO - Vet Rec 1983 Aug 13;113(7):153-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 83275588 AU - Terpstra WJ AU - Schoone GJ TI - Analysis of Leptospira antigens by crossed immunoelectrophoresis. LA - Eng MH - Animal MH - Antigen-Antibody Reactions MH - Antigens, Bacterial/*analysis MH - Heat MH - Hemagglutination Tests MH - Human MH - Immune Sera/pharmacology MH - Immunoelectrophoresis, Two-Dimensional MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis/*immunology MH - Rabbits MH - Species Specificity RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 830920 DP - 1983 Aug IS - 0300-9675 TA - Scand J Immunol PG - 113-21 SB - M SB - X CY - ENGLAND IP - 2 VI - 18 JC - UCW AA - Author EM - 8311 AB - Serovars icterohaemorrhagiae, canicola, and arboreae of pathogenic Leptospira interrogans and serovar patoc of saprophytic L. biflexa were examined by crossed immunoelectrophoresis. A close antigenic relationship was found between the interrogans serovars, particularly between icterohaemorrhagiae and canicola. To a much lesser extent cross- reactions were found between interrogans serovars and patoc. Comparison of three different antigenic preparations of icterohaemorrhagiae by tandem crossed immunoelectrophoresis and by absorption experiments with the patoc reference system showed the presence of several common broadly reactive antigens. Antigen 1 of the reference system, a genus- specific heat-stable protein antigen, was found in all antigenic preparations. It is a diagnostically important antigen. PMID- 6879113 CU - 91 SO - Scand J Immunol 1983 Aug;18(2):113-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84047911 AU - Siniak KM AU - Kas'ianenko AM AU - Kas'ianenko TI TI - [Prerequisites for the ecological prognosis of tularemia and leptospirosis foci in human activities in the national economy] LA - Rus MH - *Agriculture MH - Animal MH - *Disease Reservoirs MH - Disease Vectors MH - Ecology MH - Human MH - Leptospirosis/economics/*epidemiology MH - Prognosis MH - Rodentia MH - Tularemia/economics/*epidemiology MH - Ukraine PT - JOURNAL ARTICLE DA - 831217 DP - 1983 Aug IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 62-6 SB - M CY - USSR IP - 8 JC - Y9O EM - 8402 PMID- 6637270 CU - 88 TT - Predposylki dlia ekologicheskogo prognozirovaniia ochagov tuliaremii i leptospiroza v sviazi s narodnokhoziaistvennoi deiatel'-nost'iu cheloveka. SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Aug;(8):62-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 84047900 AU - Levina LF AU - Volina EG AU - Soboleva GL AU - Arutiunova GA TI - [Comparative study of the phospholipase activity of pathogenic and saprophytic Leptospira cultured on a serum-lecithin agar] LA - Rus MH - Agar/metabolism MH - Animal MH - Comparative Study MH - Culture Media/*metabolism MH - English Abstract MH - Hamsters MH - Leptospira interrogans/*enzymology/pathogenicity MH - Mesocricetus MH - Phosphatidylcholines/metabolism MH - Phospholipases/*metabolism MH - Virulence RN - EC 3.1.- (Phospholipases) RN - 0 (Culture Media) RN - 0 (Phosphatidylcholines) RN - 9002-18-0 (Agar) PT - JOURNAL ARTICLE DA - 831217 DP - 1983 Aug IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 27-31 SB - M CY - USSR IP - 8 JC - Y9O AA - Author EM - 8402 AB - The phospholipase activity of leptospires cultivated on serum-lecithin agar has been studied. Two zones of changes in the medium have been found to appear around the colonies of saprophytic Leptospira strains: transparent (5.25 +/- 2.09 mm wide) and turbid (6.90 +/- +/- 1.46 mm wide), which is linked with the production of phospholipases A and C. Only a single clear zone is formed around the colonies of pathogenic strains due to the production of phospholipase A. At the same time virulent Leptospira strains show greater phospholipase activity (the zones are 6.0 +/- 1.2 mm wide) than avirulent strains (the zones are 1.6 +/- +/- 0.04 mm wide). PMID- 6637268 CU - 92 TT - Sravnitel'noe izuchenie fosfolipazmoi aktivnosti patogennykh i saprofitnykh leptospir pri kul'tivirovanii na syvorotochno-letsitinovom agare. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Aug;(8):27-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 83245697 AU - Avery TL TI - Leptospirosis and mental illness [letter] LA - Eng MH - Adult MH - Case Report MH - Child MH - Child Abuse MH - Cognition Disorders/*etiology MH - Confusion/*etiology MH - Female MH - Human MH - Leptospirosis/*complications PT - LETTER DA - 830826 DP - 1983 Jul 27 IS - 0028-8446 TA - N Z Med J PG - 589 SB - M CY - NEW ZEALAND IP - 736 VI - 96 JC - OBQ EM - 8310 PMID- 6575309 CU - 91 SO - N Z Med J 1983 Jul 27;96(736):589 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [55 medline neighbors] UI - 83303698 AU - Monaghan ML AU - Hannan J TI - Abattoir survey of bovine kidney disease. LA - Eng MH - *Abattoirs/standards MH - Age Factors MH - Amyloidosis/epidemiology/veterinary MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Comparative Study MH - Cross-Sectional Studies MH - Female MH - Hemorrhage/epidemiology/veterinary MH - Ireland MH - Kidney Diseases/epidemiology/*veterinary MH - Leptospirosis/epidemiology/veterinary MH - Lipofuscin MH - Male MH - Pigmentation Disorders/epidemiology/veterinary MH - Sex Factors RN - 0 (Lipofuscin) PT - JOURNAL ARTICLE DA - 831028 DP - 1983 Jul 16 IS - 0042-4900 TA - Vet Rec PG - 55-7 SB - M CY - ENGLAND IP - 3 VI - 113 JC - XBS AA - Author EM - 8312 AB - A survey of the prevalence and type of renal disease was carried out at a Dublin abattoir in 1979-80. Of 4166 cattle surveyed, 173 (4.2 per cent) had kidneys rejected for gross abnormalities. The rejection rate was 7.7, 1.7, 2.2 and 28 per cent for cows, bullocks, heifers and bulls, respectively. The most common reason for rejection was focal interstitial nephritis (60.1 per cent of rejected kidneys). Other lesions included cysts (26.0 per cent), pigmentation (6.4 per cent), pyelonephritis (3.5 per cent), amyloidosis (2.9 per cent), glomerulonephritis (0.6 per cent), renal atrophy (0.6 per cent) and agonal haemorrhage. PMID- 6604362 CU - 92 SO - Vet Rec 1983 Jul 16;113(3):55-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 83286611 AU - Ellinghausen HC Jr TI - Growth, cultural characteristics, and antibacterial sensitivity of Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Antibiotics/pharmacology MH - Cattle MH - Culture Media MH - Drug Resistance, Microbial MH - Hamsters MH - Leptospira interrogans/drug effects/*growth & development MH - Polysorbates/pharmacology MH - Rabbits MH - Serum Albumin, Bovine MH - Thiamine/pharmacology MH - Vitamin B 12/pharmacology RN - 0 (Antibiotics) RN - 0 (Culture Media) RN - 0 (Polysorbates) RN - 0 (Serum Albumin, Bovine) RN - 59-43-8 (Thiamine) RN - 68-19-9 (Vitamin B 12) PT - JOURNAL ARTICLE DA - 831021 DP - 1983 Jul IS - 0010-8901 TA - Cornell Vet PG - 225-39 SB - M CY - UNITED STATES IP - 3 VI - 73 JC - DRI AA - Author EM - 8312 AB - Nutrient requirements of Leptospira interrogans serovar hardjo were investigated using a 1% bovine serum albumin (BSA) medium, supplemented separately with polysorbates (Tweens) 80, 60, 40, 20, NH4Cl, and vitamins thiamine and cyanocobalamin (vitamin B12). L. hardjo was tested in vitro against 30 antibacterial compounds incorporated into semisolid medium (0.2% agar) at 3 compound concentrations. Growth was superior in polysorbate 80 (oleic acid rich) and polysorbate 40 (palmitic rich) media. A linear growth response to vitamin B12 could be shown. Hamster isolates all required thiamine and vitamin B12 for growth. The antibacterial compounds could be classed as: 100% bacteriocidal, bacteriocidal at the 2 highest concentrations, bacteriocidal at only 1 concentration, and completely noninhibitory. The tetracyclines were strongly bacteriocidal. The comparative growth rates of hamster isolates were much reduced when compared to the type strain hardjoprajitno. These studies were performed acknowledging that the polysorbates were mixtures of fatty acids. Nephelometry was used as an accepted method to monitor the synthesis of leptospiral cell mass. PMID- 6884034 CU - 92 SO - Cornell Vet 1983 Jul;73(3):225-39 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 83265334 AU - Marshall V TI - Efficacy of Leptospira vaccine [letter] LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Dog Diseases/*prevention & control MH - Dogs MH - Leptospira/*immunology MH - Leptospirosis/prevention & control/*veterinary MH - Vaccination/*veterinary RN - 0 (Bacterial Vaccines) PT - LETTER DA - 830923 DP - 1983 Jul 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 12, 34 SB - M CY - UNITED STATES IP - 1 VI - 183 JC - HAV EM - 8311 PMID- 6874516 CU - 91 SO - J Am Vet Med Assoc 1983 Jul 1;183(1):12, 34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 85097197 AU - Thek J AU - Braun BJ AU - Skiendzielewski JJ TI - The spectrum of toxic shock syndrome. LA - Eng MH - Adolescence MH - Adult MH - Case Report MH - *Emergencies MH - Epidermal Necrolysis, Toxic/diagnosis MH - Female MH - Human MH - Leptospirosis/diagnosis MH - Mucocutaneous Lymph Node Syndrome/diagnosis MH - Rocky Mountain Spotted Fever/diagnosis MH - Scarlet Fever/diagnosis MH - Shock, Septic/*diagnosis MH - Staphylococcal Infections/diagnosis MH - Stevens-Johnson Syndrome/diagnosis PT - JOURNAL ARTICLE DA - 850315 DP - 1983 Jul IS - 0735-6757 TA - Am J Emerg Med PG - 30-4 SB - M CY - UNITED STATES IP - 1 VI - 1 JC - AA2 AA - Author EM - 8505 AB - The toxic shock syndrome (TSS) is a newly-recognized entity caused by a Staphylococcal exotoxin and associated with the use of tampons for menstrual protection. Two cases are presented which demonstrate the spectrum of severity of the disease. The common nature of its early symptoms necessitates a high index of suspicion to preclude a progression to the later stages of the disease, thereby reducing morbidity and mortality. PMID- 6680606 SO - Am J Emerg Med 1983 Jul;1(1):30-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 84198705 AU - Schonberg A TI - Growth of 10 Leptospira interrogans serovars using polyvinylpyrrolidone(PVP)-treated Tween in protein-free medium. LA - Eng MH - *Culture Media MH - Leptospira interrogans/*growth & development MH - Molecular Weight MH - Polysorbates MH - *Povidone MH - Species Specificity RN - 0 (Culture Media) RN - 0 (Polysorbates) RN - 9003-39-8 (Povidone) PT - JOURNAL ARTICLE DA - 840606 DP - 1983 Jul IS - 0174-3031 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 540-4 SB - M CY - GERMANY, WEST IP - 4 VI - 254 JC - Y5N AA - Author EM - 8408 AB - Polyvinylpyrrolidone (PVP)-treated Tween was used to prepare a protein- free medium for cultivation of leptospires. 6 out of 25 media were selected for culturing 10 serovars of leptospires. The best results were achieved in a medium containing Tween treated with PVP 25000. In several subcultures 8 out of 10 serovars reached a concentration of 10(8) leptospires/ml or more, when cultured in tubes without aeration.l Only in the case of 2 serovars (Leptospira interrogans serovars grippotyphosa and tarassovi) growth was not satisfactory. The results have shown that it is possible to detoxify Tween with the aid of polyvinylpyrrolidone. In the meantime the 40th subculture of 8 strains has been prepared. PMID- 6675354 CU - 92 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1983 Jul;254(4):540-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 84065023 AU - Everard CO AU - Fraser-Chanpong GM AU - Bhagwandin LJ AU - Race MW AU - James AC TI - Leptospires in wildlife from Trinidad and Grenada. LA - Eng MH - Agglutinins/analysis MH - Animal MH - *Animals MH - *Animals, Wild MH - Antibodies, Bacterial/analysis MH - Disease Reservoirs/*veterinary MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Species Specificity MH - Support, Non-U.S. Gov't MH - Trinidad and Tobago MH - West Indies RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840107 DP - 1983 Jul IS - 0090-3558 TA - J Wildl Dis PG - 192-9 SB - M CY - UNITED STATES IP - 3 VI - 19 JC - KEM AA - Author EM - 8403 AB - Serum samples from 894 wild animals (representing 31 species) from Trinidad and Grenada were examined by the microscopic agglutination test for leptospiral antibodies; 198 were positive. These included 39 bats, 88 mongooses, six opossums, 10 peridomestic rodents, 15 forest rodents, 10 lizards, and 30 toads. Thirteen pathogenic serogroups were involved. Thirty-nine Leptospira isolates were reported from mongooses, opossums, rodents and toads. PMID- 6644917 CU - 91 SO - J Wildl Dis 1983 Jul;19(3):192-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84057011 AU - Li YJ TI - [Observations on the effect of common methods of cooking and freezing on the kidney contaminated by Leptospira] LA - Chi MH - Animal MH - *Cookery MH - English Abstract MH - *Food Microbiology MH - Freezing MH - *Heat MH - Kidney/*microbiology MH - Leptospira/*isolation & purification MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 840127 DP - 1983 Jul TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 214-5 CY - CHINA IP - 4 VI - 17 JC - D74 EM - 8403 PMID- 6641414 EA - A SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1983 Jul;17(4):214-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84052294 AU - Peet RL AU - Mercy A AU - Hustas L AU - Speed C TI - The significance of Leptospira isolated from the kidneys of slaughtered pigs. LA - Eng MH - Abattoirs MH - Animal MH - Australia MH - Kidney/*microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 831220 DP - 1983 Jul IS - 0005-0423 TA - Aust Vet J PG - 226-7 SB - M CY - AUSTRALIA IP - 7 VI - 60 JC - 9IE EM - 8402 PMID- 6639525 SO - Aust Vet J 1983 Jul;60(7):226-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 84052280 AU - Slee KJ AU - McOrist S AU - Skilbeck NW TI - Bovine abortion associated with Leptospira interrogans serovar hardjo infection. LA - Eng MH - Abortion, Veterinary/*etiology/parasitology MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/diagnosis/*etiology/parasitology MH - Female MH - Leptospira interrogans/immunology MH - Pregnancy MH - Weil's Disease/diagnosis/parasitology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 831220 DP - 1983 Jul IS - 0005-0423 TA - Aust Vet J PG - 204-6 SB - M CY - AUSTRALIA IP - 7 VI - 60 JC - 9IE AA - Author EM - 8402 AB - During 1981, 265 bovine abortions were investigated by serological and histological methods for evidence of leptospiral infection. Leptospires were demonstrated in the tissues of 10 foetuses by a Levaditi silver impregnation technique. Serological testing of maternal sera indicated that Leptospira interrogans serovar hardjo was associated with 5 of the abortions while the remaining 5 were due to L. interrogans serovar pomona infection. In cases of abortion associated with L. interrogans serovar hardjo leptospires were readily demonstrated in foetal liver, kidney, intestine and heart. They were demonstrated less often in lung and placenta and could not be found in foetal brain. Autolysis did not appear to interfere with the demonstration of leptospires by silver impregnation. No lesions attributable to leptospiral infection were seen in placentas but mild interstitial nephritis was found in some of the foetuses. Fourteen other cows had serological evidence of recent leptospiral infection but leptospires were not detected in foetal tissues. Histological examination of silver impregnated foetal tissues in combination with the microscopic agglutination test was shown to be an effective method for diagnosing abortion associated with L. interrogans serovar hardjo in cattle. PMID- 6639516 CU - 91 SO - Aust Vet J 1983 Jul;60(7):204-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [82 medline neighbors] UI - 84017026 AU - Hathaway SC AU - Little TW AU - Stevens AE AU - Ellis WA AU - Morgan J TI - Serovar identification of leptospires of the Australis serogroup isolated from free-living and domestic species in the United Kingdom. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Animals/*microbiology MH - Animals, Domestic/*microbiology MH - Animals, Wild/*microbiology MH - Great Britain MH - Leptospira/*classification MH - Serotyping/veterinary PT - JOURNAL ARTICLE DA - 831123 DP - 1983 Jul IS - 0034-5288 TA - Res Vet Sci PG - 64-8 SB - M CY - ENGLAND IP - 1 VI - 35 JC - R7D AA - Author EM - 8401 AB - Eighteen isolates from the Australis serogroup from free-living and domestic animals were identified using the cross agglutination absorption test. Serovar muenchen was found only in England and Wales in wood mice, short tailed and bank voles, a grey squirrel and a pig. Serovar bratislava was found in hedgehogs in England, Wales and Northern Ireland and also in a brown rat from Northern Ireland. Serovar bratislava was isolated from sheep in both England and Northern Ireland and from horses in Northern Ireland. The distribution of these serovars in relation to possible maintenance hosts is discussed. PMID- 6622847 CU - 90 SO - Res Vet Sci 1983 Jul;35(1):64-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84069436 AU - Adler B AU - Faine S TI - A pomona serogroup-specific, agglutinating antigen in Leptospira, identified by monoclonal antibodies. LA - Eng MH - Animal MH - Antibodies, Monoclonal/*immunology MH - Antibody Specificity MH - Antigens, Bacterial/*analysis MH - Hemagglutination MH - Human MH - Immunodiffusion MH - Leptospira/*immunology MH - Lipopolysaccharides/immunology MH - Mice MH - Phagocytosis MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Monoclonal) RN - 0 (Antigens, Bacterial) RN - 0 (Lipopolysaccharides) PT - JOURNAL ARTICLE DA - 840107 DP - 1983 Jul IS - 0031-3025 TA - Pathology PG - 247-50 SB - M CY - AUSTRALIA IP - 3 VI - 15 JC - OTA AA - Author EM - 8403 AB - Monoclonal antibodies were produced by hybridoma cell lines derived by fusion of mouse NS-1 myeloma cells with splenocytes from mice immunized with Leptospira interrogans serovar pomona. One hybridoma (A3) produced an IgG2a antibody which agglutinated all leptospires of the Pomona serogroup but not leptospires representative of serovars of any other serogroup. The antibody precipitated in immunodiffusions with either alkali- or phenol-extracted lipopolysaccharide and also with the TM antigen of Yanagawa et al., indicating a common determinant on both antigens. A3 antibody opsonized viable leptospires for phagocytosis by mouse macrophages in vitro. PMID- 6417619 CU - 91 SO - Pathology 1983 Jul;15(3):247-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 84198704 AU - Terpstra WJ AU - Jabboury-Postema J AU - Korver H TI - Immunoperoxidase staining of leptospires in blood and urine. LA - Eng MH - Animal MH - Blood/*microbiology MH - Cattle MH - Hamsters MH - Human MH - *Immunoenzyme Techniques MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/diagnosis MH - Urine/*microbiology PT - JOURNAL ARTICLE DA - 840606 DP - 1983 Jul IS - 0174-3031 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 534-9 SB - M CY - GERMANY, WEST IP - 4 VI - 254 JC - Y5N AA - Author EM - 8408 AB - Immunoperoxidase staining of leptospires is a relatively simple method giving satisfactory results. Leptospires can be identified by the specificity of the serological reaction and by their characteristic morphology. The method could contribute to a rapid diagnosis by the direct demonstration of leptospires in clinical specimens. PMID- 6372331 CU - 90 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1983 Jul;254(4):534-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84019961 AU - Golubev MV AU - Litvin VIu TI - [Leptospira population ecology. II. An attempt to assess the number in the soil and the epizootic potential of infected spots] LA - Rus MH - Animal MH - Animals, Wild MH - Carrier State/epidemiology/microbiology MH - *Disease Reservoirs MH - Ecology MH - English Abstract MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/*microbiology MH - Russia MH - *Soil Microbiology MH - Time Factors PT - JOURNAL ARTICLE DA - 831123 DP - 1983 Jul IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 106-9 SB - M CY - USSR IP - 7 JC - Y9O AA - Author EM - 8401 AB - Leptospires released with a carrier's urine were found to inhabit the upper layer of the soil 1 cm deep at a radius of 1-2 cm from the place of their penetration into the soil. A sharp drop in the number of leptospires in the "infected spot" was shown to occur; in 6-12 hours their concentration became no different from that in the intact soil. Most of such spots retained their infective capacity for 6 hours (up to 2 days), though the presence of leptospires at low concentration was registered for 10 days (the term of observation). The infective capacity was probably maintained by the regular addition of leptospires with carriers' urine. PMID- 6226165 CU - 92 TT - K populiatsionnoi ekologii leptospir. Soobshchenie II. Opyt otsenki chislennosti v pochve i epizooticheskogo potentsiala zarazhennykh tochek. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Jul;(7):106-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84002327 AU - Klimes A AU - Cerny J AU - Kadlec V TI - [A focus of leptospirosis in a deep mine] LA - Cze MH - Animal MH - Case Report MH - *Coal Mining MH - *Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*diagnosis MH - Male MH - Mice/*microbiology MH - Middle Age MH - Occupational Diseases/*diagnosis MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 831123 DP - 1983 Jul IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 218-23 CY - CZECHOSLOVAKIA IP - 4 VI - 32 JC - CSH EM - 8401 PMID- 6225537 CU - 92 TT - Ohnisko leptospirozy v hlubinnem dole. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1983 Jul;32(4):218-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83273382 AU - Raoult D AU - Jeandel P AU - Rougier Y AU - Auger C AU - Mailloux M TI - [Late positive blood culture in leptospirosis (letter)] LA - Fre MH - Aged MH - Blood/microbiology MH - Case Report MH - Female MH - Human MH - Leptospirosis/*microbiology MH - Male MH - Middle Age MH - Time Factors PT - LETTER DA - 830920 DP - 1983 Jun 25 IS - 0755-4982 TA - Presse Med PG - 1726-7 SB - M SB - X CY - FRANCE IP - 27 VI - 12 JC - PMT EM - 8311 PMID- 6224170 CU - 92 TT - Hemocultures tardivement positives dans les leptospiroses. SO - Presse Med 1983 Jun 25;12(27):1726-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 83254169 AU - Waltman WD 2d AU - Dawe DL TI - Enzyme-linked immunosorbent assay for the detection of antileptospiral antibodies in swine sera. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Enzyme-Linked Immunosorbent Assay MH - Leptospira/immunology MH - Leptospirosis/immunology/*veterinary MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830817 DP - 1983 Jun IS - 0002-9645 TA - Am J Vet Res PG - 1120-2 SB - M CY - UNITED STATES IP - 6 VI - 44 JC - 40C AA - Author EM - 8310 AB - A genus-specific enzyme-linked immunosorbent assay (ELISA) was applied to the detection of antileptospiral antibodies in swine sera. Results of the ELISA directly correlated with the results of the microscopic agglutination test. The ELISA had a sensitivity of 100%, specificity of 86.4%, and predictive accuracy of 91.3%. Because the ELISA is a simple and extremely accurate test, it lends itself as a diagnostic screening test for large numbers of samples. PMID- 6870018 CU - 91 SO - Am J Vet Res 1983 Jun;44(6):1120-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83214801 AU - Deodhar L AU - Krishnan K AU - Chaphekar AG TI - Leptospirosis with bacteriologic diagnosis. LA - Eng MH - Adolescence MH - Animal MH - Case Report MH - Guinea Pigs MH - Human MH - Leptospira MH - Leptospirosis/*diagnosis/microbiology MH - Male MH - Rats PT - JOURNAL ARTICLE DA - 830729 DP - 1983 Jun IS - 0022-1899 TA - J Infect Dis PG - 1107 SB - A SB - M CY - UNITED STATES IP - 6 VI - 147 JC - IH3 EM - 8309 PMID- 6854070 SO - J Infect Dis 1983 Jun;147(6):1107 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84036059 AU - Herr S AU - Winnen GM TI - The first isolation of Leptospira interrogans serovar pomona from cattle in Botswana. LA - Eng MH - Abortion, Veterinary/etiology/*microbiology MH - Animal MH - Botswana MH - Cattle MH - Female MH - Leptospira interrogans/*isolation & purification MH - Pregnancy MH - Serotyping MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 831217 DP - 1983 Jun IS - 0301-0732 TA - J S Afr Vet Assoc PG - 83-4 SB - M CY - SOUTH AFRICA IP - 2 VI - 54 JC - JZH AA - Author EM - 8402 AB - Serological evidence for the occurrence of L. pomona associated with abortions in cattle was supported by the successful isolation of the organism from the urine of a cow. Leptospirosis should be considered as a possible cause of abortion even in relatively dry regions. PMID- 6631909 SO - J S Afr Vet Assoc 1983 Jun;54(2):83-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84026419 AU - Li ZG TI - [Preliminary report on isolation of pathogenic Leptospira in Ningxia Hui autonomous region] LA - Chi MH - Animal MH - English Abstract MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 831220 DP - 1983 Jun TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 146-7 CY - CHINA IP - 3 VI - 4 JC - CQG EM - 8402 PMID- 6627359 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1983 Jun;4(3):146-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 84010593 AU - Johnston JH AU - Lloyd J AU - McDonald J AU - Waitkins S TI - Leptospirosis--an occupational disease of soldiers. LA - Eng MH - Adult MH - Case Report MH - Germany, West MH - Great Britain MH - Human MH - Leptospirosis/*etiology MH - Male MH - *Military Medicine MH - Occupational Diseases/*etiology MH - Weil's Disease/*etiology PT - JOURNAL ARTICLE DA - 831123 DP - 1983 Jun IS - 0035-8665 TA - J R Army Med Corps PG - 111-4 SB - M CY - ENGLAND IP - 2 VI - 129 JC - JV6 AA - Author EM - 8401 AB - Two cases of leptospirosis are described in soldiers who fell into a river together. One developed Weil's disease due to icterohaemorrhagiae serogroup and the other "Mud-Fever" due to grippotyphosa serogroup. The organisms were initially cultured in standard blood culture media. There were six cases of leptospirosis in BAOR in the 10 years to 1980 giving an incidence 10 times greater than in the civil population of UK and West Germany. Leptospirosis is an occupational disease of soldiers in BAOR and the health risks of fresh water immersion should be publicised. PMID- 6620235 SO - J R Army Med Corps 1983 Jun;129(2):111-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [97 medline neighbors] UI - 83304596 AU - Golubev MV AU - Litvin VIu TI - [Population ecology of leptospires. 1. An experience with evaluation of leptospira count in a carrier and the intensity of elimination in the urine] LA - Rus MH - Animal MH - *Bacteriuria MH - Carrier State/*microbiology MH - Diuresis MH - Ecology MH - English Abstract MH - Leptospira/*isolation & purification MH - Rodentia/*microbiology/urine PT - JOURNAL ARTICLE DA - 831008 DP - 1983 Jun IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 60-3 SB - M CY - USSR IP - 6 JC - Y9O AA - Author EM - 8312 AB - The number of L. hebdomadis and L. grippotyphosa in the body of tundra voles (Microtus oeconomicus) has been shown to be approximately 500-800 million; about 100 million of them are daily eliminated from the body of a vole with urine. About 70% of the total volume and separate portions of urine contain leptospires, a single portion of urine containing about 2 million microbial cells. These data have proved to be the same for both L. hebdomadis and L. grippotyphosa. PMID- 6613420 TT - K populiatsionnoi ekologii leptospir. Soobshchenie 1. Opyt otsenki chislennosti leptospir v organizme nositelia i intensivnosti vyvedeniia s mochoi. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Jun;(6):60-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 83304587 AU - Anan'ina IuV AU - Chernukha IuG TI - [Bactericidal activity of normal sera from various animal species against pathogenic and saprophytic leptospires] LA - Rus MH - Animal MH - *Blood Bactericidal Activity MH - Cattle MH - Chickens MH - Comparative Study MH - English Abstract MH - Immunity, Natural MH - Leptospira/classification/*immunology/pathogenicity MH - Rabbits MH - Serotyping MH - Sheep MH - Species Specificity PT - JOURNAL ARTICLE DA - 831008 DP - 1983 Jun IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 33-7 SB - M CY - USSR IP - 6 JC - Y9O AA - Author EM - 8312 AB - The leptospirocidal activity of 5 animal species against L. interrogans, L. biflexa and L. kazachstanica I and II, belonging to different serogroups and serovars, was studied. Cattle and sheep sera had no lytic effect on 36.9-40.1% of pathogenic Leptospira strains, but other pathogenic strains, as well as saprophytes, were lyzed by these sera. L. pomona and L. grippotyphosa exhibited high resistance to cattle serum, the latter being also resistant to sheep serum. PMID- 6613419 TT - Bacteritsidnaia aktivnost' normal'nykh syvorotok zhivotnykh nekotorykh vidov v otnoshenii patogennykh i saprofitnykh leptospir. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Jun;(6):33-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 83304583 AU - Chernukha IuG AU - Anan'ina IuV TI - [Etiological structure of icterohemorrhagic leptospirosis in gray rats (Rattus norvegicus)] LA - Rus MH - Animal MH - English Abstract MH - Leptospira interrogans/*classification MH - Rats/*microbiology MH - Rodent Diseases/*microbiology MH - Russia MH - Serotyping MH - Weil's Disease/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 831008 DP - 1983 Jun IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 24-6 SB - M CY - USSR IP - 6 JC - Y9O AA - Author EM - 8312 AB - In 93 Leptospira strains isolated from Norwegian rats serovar determination was made. As a result, leptospires circulating among Norwegian rats were found to belong mainly to serovar copenhageni, group Icterohaemorrhagiae, while leptospires of serovar icterohaemorrhagiae, even if occurring, were found only in the animals inhabiting pigsties. Leptospirosis epizooty among rats, caused by L. icterohaemorrhagiae, took its course independently of leptospirosis epizooty among mice, caused by L. hebdomadis, and simultaneously with it. PMID- 6225275 CU - 92 TT - Etiologicheskaia struktura leptospiroza Icterohaemorrhagiae serykh krys (Rattus norvegicus). EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Jun;(6):24-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [84 medline neighbors] UI - 83304588 AU - Stoianova NA AU - Popova EM AU - Iachmenev NI AU - Sil'ianova VI AU - Semenovich VN TI - [Antigenic structure of leptospires of the Canicola serogroup isolated in the north-western regions of the RSFSR] LA - Rus MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial/*immunology MH - Cross Reactions MH - Dogs MH - English Abstract MH - Epitopes/*analysis MH - Human MH - Leptospira canicola/classification/*immunology MH - Rabbits MH - Rodentia MH - Russia MH - Serotyping MH - Swine RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 831008 DP - 1983 Jun IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 37-41 SB - M CY - USSR IP - 6 JC - Y9O AA - Author EM - 8312 AB - The comparative study of 16 Leptospira cultures, serogroup Canicola, isolated from humans and animals in different years in the North-West of the RSFSR and 2 reference strains of the Canicola serovar, Hond Utrecht IV and Kashirsky, was carried out in the agglutinin cross- adsorption tests. The absence of the antigenic homogeneity of the cultures under test was established: 9 of them proved to be identical to strain Kashirsky and 7, to strain Hond Utrecht IV. PMID- 6193662 CU - 95 TT - Kharakteristika antigennoi struktury leptospir serogruppy Canicola, vydelennykh na severo-zapade RSFSR. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Jun;(6):37-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 83191776 AU - Swart KS AU - Wilks CR AU - Jackson KB AU - Hayman JA TI - Human leptospirosis in Victoria. LA - Eng MH - Adolescence MH - Adult MH - Australia MH - Child MH - Child, Preschool MH - *Dairying MH - Female MH - Human MH - Leptospirosis/*diagnosis/epidemiology MH - Male MH - Middle Age MH - Occupational Diseases/*diagnosis MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 830617 DP - 1983 May 14 IS - 0025-729X TA - Med J Aust PG - 460-3 SB - M SB - X CY - AUSTRALIA IP - 10 VI - 1 JC - M26 AA - Author EM - 8308 AB - Between May, 1979, and May, 1981, leptospirosis was diagnosed, on the basis of serological and culture findings, in specimens from 208 of 2516 patients with symptoms which suggested leptospirosis or other zoonoses. The most common serological reactions were with serovars hardjo (69%), pomona (29%) and tarassovi (2%). There was a clear association between infection and occupation in 101 farmers, 44 meat workers and 11 meat inspectors. It would seem prudent to consider leptospirosis in the differential diagnosis of pyrexia in patients who have occupational contact with animals, and to institute appropriate serological and culture examinations. PMID- 6843428 CU - 88 SO - Med J Aust 1983 May 14;1(10):460-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83191767 AU - Faine S TI - Is leptospirosis a "rare" disease? [editorial] LA - Eng MH - *Dairying MH - Human MH - Leptospirosis/*diagnosis MH - *Meat-Packing Industry MH - Occupational Diseases/*diagnosis PT - EDITORIAL DA - 830617 DP - 1983 May 14 IS - 0025-729X TA - Med J Aust PG - 445-6 SB - M SB - X CY - AUSTRALIA IP - 10 VI - 1 JC - M26 EM - 8308 PMID- 6843419 CU - 91 SO - Med J Aust 1983 May 14;1(10):445-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 84271317 AU - Calonghi G AU - Cadeo GP AU - Nadalini A TI - [Therapy and prevention of leptospirosis] LA - Ita MH - English Abstract MH - Fever/etiology MH - Human MH - Hyperbilirubinemia/diagnosis MH - Leptospirosis/*drug therapy/prevention & control MH - Leukocyte Count MH - Meningitis/therapy MH - Penicillins/*therapeutic use MH - Peritoneal Dialysis MH - Self Administration MH - Sulfonamides/therapeutic use MH - Tetracyclines/therapeutic use MH - Uremia/diagnosis MH - Weil's Disease/therapy RN - 0 (Penicillins) RN - 0 (Sulfonamides) RN - 0 (Tetracyclines) PT - JOURNAL ARTICLE DA - 840918 DP - 1983 May 12 IS - 0026-4806 TA - Minerva Med PG - 1191-8 SB - M SB - X CY - ITALY IP - 20 VI - 74 JC - N6M AA - Author EM - 8411 AB - After a brief description of the experimental and clinical data on antibiotic treatment of leptospirosis, personal experience of 47 patients is reported. The administration of antibiotics to these patients with Weil's disease, lymphocytic meningitis or grippe-like syndrome began well after the onset of the infection and appeared to have little therapeutic effect. The symptomatic therapy of leptospirosis, especially in the form of Weil's disease with serious renal insufficiency is then referred to and the early use of peritoneal dialysis is recommended. General specific and immunizing (vaccination) prophylaxis procedures are then described. PMID- 6678400 CU - 92 TT - Terapia e profilassi della leptospirosi. EA - A SO - Minerva Med 1983 May 12;74(20):1191-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84271316 AU - Fiori GP AU - Tafuri A AU - Iberti M TI - [Possibilities and current technics of dialysis in leptospirosis with severe renal damage] LA - Ita MH - Adult MH - Case Report MH - English Abstract MH - Female MH - Human MH - Jaundice/etiology MH - Kidney Failure, Acute/*etiology/therapy MH - Leptospirosis/complications/*therapy MH - Male MH - Middle Age MH - *Peritoneal Dialysis PT - JOURNAL ARTICLE DA - 840918 DP - 1983 May 12 IS - 0026-4806 TA - Minerva Med PG - 1187-90 SB - M SB - X CY - ITALY IP - 20 VI - 74 JC - N6M AA - Author EM - 8411 AB - Three patients with severe liver and renal failure admitted to the Infectious Diseases Department of the Alessandria for suspected leptospirosis in the second half of 1979 are presented. In one case, the agent responsible was Leptospira icterohaemorrhagiae AB Wjnberg strain, in another Gram-negative sepsis, and in the third acute pancreatitis associated with serious Escherichia coli infection. An account is given of the peritoneal dialysis technique that led to successful resolution of the serious liver and renal failure. PMID- 6678399 TT - Possibilita e tecniche attuali di dialisi nella leptospirosi con grave danno renale. EA - A SO - Minerva Med 1983 May 12;74(20):1187-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 84271315 AU - Suter F AU - Minoli L AU - Parisi A AU - Filice C AU - Maserati R AU - Farina CF TI - [Current clinical aspects of leptospirosis] LA - Ita MH - Adolescence MH - Adult MH - Ampicillin/therapeutic use MH - Child MH - English Abstract MH - Fever/etiology MH - Hepatitis/*etiology MH - Human MH - Leptospira/classification MH - Leptospirosis/*complications/therapy MH - Meningitis/etiology MH - Middle Age MH - Nephritis/*etiology MH - Penicillins/therapeutic use MH - Peritoneal Dialysis RN - 0 (Penicillins) RN - 69-53-4 (Ampicillin) PT - JOURNAL ARTICLE DA - 840918 DP - 1983 May 12 IS - 0026-4806 TA - Minerva Med PG - 1179-86 SB - M SB - X CY - ITALY IP - 20 VI - 74 JC - N6M AA - Author EM - 8411 AB - Leptospirosis is still endemic in the Po valley. It has an extremely protean clinical picture. In a series of 79 cases diagnosed at Pavia in the period 1970-79 hepatonephritic forms were the most common (29.1%), followed by febrile or pseudo-influenza forms (25.3%), hepatitis (20.2%), nephritis (17.8%), and meningitis (7.6%). Febrile hepatonephritis was always accompanied by the most severe pictures. Timely antibiotic management with penicillin or ampicillin, and above all the early use of peritoneal dialysis (carried in 10 subjects) enable a final cure to be obtained even in these cases. The only death in that series did not appear to be ascribable to the disease itself. PMID- 6678398 CU - 92 TT - Aspetti clinici attuali delle leptospirosi. EA - A SO - Minerva Med 1983 May 12;74(20):1179-86 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 83254135 AU - Thiermann AB AU - Garrett LA TI - Enzyme-linked immunosorbent assay for the detection of antibodies to Leptospira interrogans serovars hardjo and pomona in cattle. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*diagnosis MH - Comparative Study MH - Cross Reactions MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - Leptospira interrogans/*immunology MH - Pregnancy MH - Vaccination/veterinary MH - Weil's Disease/diagnosis/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830811 DP - 1983 May IS - 0002-9645 TA - Am J Vet Res PG - 884-7 SB - M CY - UNITED STATES IP - 5 VI - 44 JC - 40C AA - Author EM - 8310 AB - An enzyme-linked immunosorbent assay (ELISA), which used the phenol phase of a hot phenol-water extraction as antigen, and the microscopic agglutination test were compared for the detection of antibodies to Leptospira interrogans serovars hardjo and pomona in cattle. Among serum samples from vaccinated cattle, the ELISA (using antiglobulin) was positive to 64% with hardjo antigen and to 78% with pomona antigen, whereas the microscopic agglutination test was positive to only 18% with hardjo and 23% with pomona. There were no ELISA reactions observed among known negative-control samples. The ELISA, using antiglobulin conjugate, was overall a more sensitive technique for the detection of leptospiral antibodies in cattle. PMID- 6869998 CU - 91 SO - Am J Vet Res 1983 May;44(5):884-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [45 medline neighbors] UI - 84026883 AU - Voelckel J TI - [Diseases arising from contact with animals in an urban tropical milieu] LA - Fre MH - Africa MH - Animal MH - Dogs MH - Human MH - Insect Control MH - Laos MH - Leptospirosis/transmission MH - Mosquito Control MH - Polynesia MH - Rabies/transmission MH - Rats MH - Rodent Control MH - South America MH - *Tropical Climate MH - *Urbanization MH - Zoonoses/prevention & control/*transmission PT - JOURNAL ARTICLE DA - 831220 DP - 1983 May-Jun IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 293-9 SB - M CY - FRANCE IP - 3 VI - 76 JC - C4G EM - 8402 PMID- 6627547 TT - Maladies de contact animal en milieu urbain tropical. SO - Bull Soc Pathol Exot Filiales 1983 May-Jun;76(3):293-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84009271 AU - Tamai T TI - [Characterization of monoclonal antibodies against Leptospira causing Weil's disease] LA - Jpn MH - Animal MH - Antibodies, Monoclonal/*immunology MH - Cell Fusion MH - English Abstract MH - Human MH - Leptospira/classification/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Serotyping MH - Weil's Disease/*microbiology RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 831123 DP - 1983 May IS - 0387-5911 TA - Kansenshogaku Zasshi PG - 394-404 CY - JAPAN IP - 5 VI - 57 JC - IJR EM - 8401 PMID- 6413616 CU - 91 EA - A SO - Kansenshogaku Zasshi 1983 May;57(5):394-404 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [78 medline neighbors] UI - 83186039 AU - Westfall HN AU - Charon NW AU - Peterson DE TI - Multiple pathways for isoleucine biosynthesis in the spirochete Leptospira. LA - Eng MH - Comparative Study MH - Isoleucine/*biosynthesis MH - Leptospira/classification/genetics/*metabolism MH - Leptospira interrogans/*metabolism MH - Leucine/pharmacology MH - Pyruvates/metabolism MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Threonine/metabolism RN - 0 (Pyruvates) RN - 127-17-3 (Pyruvic Acid) RN - 7004-09-3 (Isoleucine) RN - 7005-03-0 (Leucine) RN - 72-19-5 (Threonine) PT - JOURNAL ARTICLE ID - DE 04645/DE/NIDR ID - 5 S07-RR05433/RR/NCRR DA - 830617 DP - 1983 May IS - 0021-9193 TA - J Bacteriol PG - 846-53 SB - M CY - UNITED STATES IP - 2 VI - 154 JC - HH3 AA - Author EM - 8308 AB - Spirochetes of the genus Leptospira have previously been shown to use an unusual pathway to synthesize isoleucine. For reasons of convenience, we assume that only one unusual pathway is found in the genus, and we refer to it as the pyruvate pathway. We determined the distribution of this pyruvate pathway in representatives of the seven Leptospira DNA hybridization groups. Our method included labeling the representative strains with radioactive carbon dioxide and other radioactive precursors, fractionating the cells, and determining the specific activities (counts detected per nanomole) of the amino acids found in the protein fractions. On the basis of isoleucine biosynthesis, we found that the genus can be classified as follows: class I primarily, if not exclusively, uses the well-known threonine pathway; class II uses mostly the pyruvate pathway, with a minor amount of isoleucine being synthesized via the threonine pathway; and class III uses the pyruvate pathway exclusively. No relationship appears to exist between the degree of DNA hybridization and the classes of isoleucine biosynthesis. Although the precise intermediates on the pyruvate pathway are unknown, the origin of the carbon skeleton of isoleucine synthesized by this pathway is consistent with a borrowing of the leucine biosynthetic enzymes. However, we found that the pyruvate pathway is not controlled by leucine and that the two isoleucine pathways are independently regulated. Finding major and highly evolved multiple biosynthetic pathways of a specific amino acid within one genus is unique, and, conceivably, represents phylogenetic diversity within Leptospira. PMID- 6404889 CU - 96 SO - J Bacteriol 1983 May;154(2):846-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 84195342 AU - Macedo SL AU - Cornide RI AU - Caceres I TI - [Endemic strains of pathogenic Leptospirae isolated in Latin America and the Caribbean] LA - Spa MH - Animal MH - Animals/*microbiology MH - Animals, Domestic/*microbiology MH - Animals, Wild/*microbiology MH - Disease Reservoirs MH - English Abstract MH - Human MH - Latin America MH - Leptospira/*isolation & purification MH - Leptospirosis/*microbiology/veterinary MH - Support, Non-U.S. Gov't MH - West Indies PT - JOURNAL ARTICLE DA - 840619 DP - 1983 May-Aug IS - 0375-0760 TA - Rev Cubana Med Trop PG - 186-92 CY - CUBA IP - 2 VI - 35 JC - RPX EM - 8408 PMID- 6371944 CU - 90 TT - Cepas endemicas de leptospiras patogenas aisladas en America Latina y el Caribe. EA - A SO - Rev Cubana Med Trop 1983 May-Aug;35(2):186-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 83250596 AU - Woods SB AU - Maley AD AU - Frerichs GN AU - Bailey J TI - Isolation of a hamster lethal strain of Leptospira interrogans serotype hardjo. LA - Eng MH - Animal MH - Bacterial Vaccines MH - Brain/microbiology MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Hamsters/*microbiology MH - Kidney/microbiology MH - Kidney Diseases/microbiology/*veterinary MH - Leptospira interrogans/immunology/*isolation & purification/pathogenicity MH - Mesocricetus/*microbiology MH - Rodent Diseases/*microbiology MH - Vaccination/veterinary MH - Weil's Disease/microbiology/*veterinary RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 830811 DP - 1983 Apr 30 IS - 0042-4900 TA - Vet Rec PG - 437-8 SB - M CY - ENGLAND IP - 18 VI - 112 JC - XBS EM - 8310 PMID- 6868308 CU - 91 SO - Vet Rec 1983 Apr 30;112(18):437-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [43 medline neighbors] UI - 83294839 AU - Foreyt WJ AU - Smith TC AU - Evermann JF AU - Heimer WE TI - Hematologic, serum chemistry and serologic values of Dall's sheep (Ovis dalli dalli) in Alaska. LA - Eng MH - Alaska MH - Animal MH - Animals, Wild MH - Antibodies/analysis MH - Blood Cell Count/veterinary MH - Blood Chemical Analysis/veterinary MH - Female MH - Male MH - Sheep/*blood/genetics/immunology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies) PT - JOURNAL ARTICLE DA - 831021 DP - 1983 Apr IS - 0090-3558 TA - J Wildl Dis PG - 136-9 SB - M CY - UNITED STATES IP - 2 VI - 19 JC - KEM AA - Author EM - 8312 AB - In June 1979, 73 Dall's sheep were captured near Tok, Alaska to determine selected hematologic and serum metabolite parameters and to determine the presence of antibodies to selected pathogens. Hematology and serum metabolite values were compared with values for domestic sheep and bighorn sheep (Ovis canadensis). Antibodies were detected against Brucella sp. (4%), Campylobacter feti (30%), contagious ecthyma virus (23%) and bovine parainfluenza type 3 virus (1%). Antibodies were not detected against Anaplasma sp., Leptospira sp., bovine virus diarrhea virus, bluetongue virus, infectious bovine rhinotracheitis virus, ovine progressive pneumonia, and Toxoplasma sp. PMID- 6887435 CU - 91 SO - J Wildl Dis 1983 Apr;19(2):136-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83264886 AU - English J AU - Molloy W AU - Murnaghan D AU - Whelton M TI - Leptospirosis in South West Ireland. LA - Eng MH - Adult MH - Aged MH - Agricultural Workers' Diseases/*diagnosis MH - Human MH - Ireland MH - Leptospirosis/*diagnosis/physiopathology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 830909 DP - 1983 Apr IS - 0021-1265 TA - Ir J Med Sci PG - 145-8 CY - IRELAND IP - 4 VI - 152 JC - GXB EM - 8311 PMID- 6874281 SO - Ir J Med Sci 1983 Apr;152(4):145-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83264296 AU - Ratnam S AU - Sundararaj T AU - Thyagarajan SP AU - Rao RS AU - Madanagopalan N AU - Subramanian S TI - Serological evidence of leptospirosis in jaundice and pyrexia of unknown origin. LA - Eng MH - Adolescence MH - Adult MH - Antibodies, Bacterial/*analysis MH - Child MH - Child, Preschool MH - Female MH - Fever of Unknown Origin/*etiology/immunology MH - Human MH - Infant MH - Jaundice/*etiology/immunology MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/immunology MH - Male MH - Middle Age MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830920 DP - 1983 Apr IS - 0019-5340 TA - Indian J Med Res PG - 427-30 CY - INDIA VI - 77 JC - GJF EM - 8311 PMID- 6874030 CU - 91 SO - Indian J Med Res 1983 Apr;77:427-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 83244192 AU - Awad-Masalmeh A AU - Willinger H TI - Evaluation of usefulness of 2-mercapto-ethanol treatment in serodiagnosis of swine leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Heterophile/immunology MH - Leptospirosis/*diagnosis MH - Mercaptoethanol/*diagnostic use MH - Species Specificity MH - Swine MH - Swine Diseases/*diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Heterophile) RN - 60-24-2 (Mercaptoethanol) PT - JOURNAL ARTICLE DA - 830811 DP - 1983 Apr IS - 0391-5352 TA - Microbiologica PG - 133-43 SB - M CY - ITALY IP - 2 VI - 6 JC - MXR AA - Author EM - 8310 AB - Serum samples of piglets infected artificially or naturally, respectively, with Leptospira pomona were treated with 2-mercapto- ethanol (ME) and tested in the microscopic agglutination test in comparison with untreated sera. Serum-treatment with ME showed two beneficial effects, one being the total elimination of heterotypic reactions, the other the reduction or elimination, respectively, of early antibodies, presumably belonging to the IgM class. Accordingly, two practical implications can be derived from our results. The ratio of ME-sensitive and ME-resistant antibody titers allows the recognition of early leptospira infections. The total suppression by ME of heterotypic agglutination eliminates the danger of determining the wrong leptospira type as causative agent, a crucial problem encountered not infrequently with agglutination testing of untreated sera. Recognition of early cases of swine leptospirosis by ME-treatment of sera is particularly useful, as the complement fixative reaction, successfully used in other species for the same purpose, is inappropriate in swine sera owing to their autolytic properties. Furthermore by elimination of all heterotypic reactions the ME-method gives better chances for the determination of the causative agent and hence for correct interpretation of serological results. ME-treatment is considered as a useful help in serodiagnosis of field samples, in which determination of duration of infection is essential or in which heterotypic agglutination is obscuring the etiological leptospira type. PMID- 6688116 CU - 91 SO - Microbiologica 1983 Apr;6(2):133-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 84198673 AU - Cinco M AU - Banfi E TI - Activation of complement by leptospires and its bactericidal activity. LA - Eng MH - Animal MH - Complement/*immunology MH - *Complement Activation MH - Complement 4/deficiency MH - Guinea Pigs MH - Leptospira/*immunology/pathogenicity MH - Leptospira interrogans/*immunology/pathogenicity MH - Species Specificity RN - 0 (Complement 4) RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 840607 DP - 1983 Apr IS - 0174-3031 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 261-5 SB - M CY - GERMANY, WEST IP - 2 VI - 254 JC - Y5N AA - Author EM - 8408 AB - Bactericidal activity of complement was found to be effective on saprophytic Leptospira biflexa strains and not on Leptospira interrogans strains, by means of viable counting; the killing effect on saprophytic strains was probably due to a direct activation of the complement system via the alternative pathway. On the contrary the pathogenic strains seemed to activate the complement at a lower extent and were, in any case, resistant to the lytic action of the activated complement. PMID- 6675348 CU - 92 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1983 Apr;254(2):261-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84046165 AU - Jayanthi V AU - Ratnam S AU - Madanagopalan N AU - Ramachandran MS AU - Subramanian S TI - Clinical profile of leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Diagnosis, Differential MH - Female MH - Hepatitis, Viral, Human/diagnosis MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - Meningitis/diagnosis MH - Middle Age PT - JOURNAL ARTICLE DA - 831217 DP - 1983 Apr-Jun IS - 0250-636X TA - Trop Gastroenterol PG - 100-3 CY - INDIA IP - 2 VI - 4 JC - WGI EM - 8402 PMID- 6636293 SO - Trop Gastroenterol 1983 Apr-Jun;4(2):100-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83187683 AU - Song G AU - Hang CS AU - Qui XZ AU - Ni DS AU - Liao HX AU - Gao GZ AU - Du YL AU - Xu JK AU - Wu YS AU - Zhao JN AU - Kong BX AU - Wang ZS AU - Zhang ZQ AU - Shen HK AU - Zhou N TI - Etiologic studies of epidemic hemorrhagic fever (hemorrhagic fever with renal syndrome). LA - Eng MH - Animal MH - Antibodies, Viral/analysis MH - Antigens, Viral/analysis MH - China MH - Disease Reservoirs MH - Hantavirus/immunology MH - Hemorrhagic Fever with Renal Syndrome/epidemiology/*immunology/transmission MH - Human MH - Lung/microbiology MH - Muridae/microbiology MH - Rats/microbiology RN - 0 (Antibodies, Viral) RN - 0 (Antigens, Viral) PT - JOURNAL ARTICLE DA - 830617 DP - 1983 Apr IS - 0022-1899 TA - J Infect Dis PG - 654-9 SB - A SB - M CY - UNITED STATES IP - 4 VI - 147 JC - IH3 AA - Author EM - 8308 AB - Two strains of epidemic hemorrhagic fever (EHF) virus were isolated from the lung tissues of Apodemus agrarius mice that were captured in an area where EHF is endemic. The strains were isolated by passages in A. agrarius mice from a nonendemic area. Identification of the isolates by usual procedures was confirmed by repeated blind tests with coded sera. Contamination with certain known viruses such as reovirus, adenovirus (types 3 and 7), and other pathogens, such as murine typhus rickettsiae and Leptospira, which may be naturally present in wild rodents, appeared to have been ruled out. The antigen slides made from these isolates are in use in the specific diagnosis and seroepidemiologic studies of EHF. The first successful application is the serodiagnosis of a mild type of hemorrhagic fever that occurs with characteristic epidemiologic features in certain provinces of China. PMID- 6132949 CU - 94 SO - J Infect Dis 1983 Apr;147(4):654-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 83199120 AU - Ellis WA AU - Bryson DG AU - Neill SD AU - McParland PJ AU - Malone FE TI - Possible involvement of leptospires in abortion, stillbirths and neonatal deaths in sheep. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Female MH - Fetal Death/etiology/*veterinary MH - Leptospira/classification/immunology MH - Leptospirosis/complications/diagnosis/*veterinary MH - Pregnancy MH - Serotyping/veterinary MH - Sheep MH - Sheep Diseases/*etiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830617 DP - 1983 Mar 26 IS - 0042-4900 TA - Vet Rec PG - 291-3 SB - M CY - ENGLAND IP - 13 VI - 112 JC - XBS AA - Author EM - 8308 AB - Using culture, immunofluorescence and fetal serology, leptospiral infection was demonstrated in aborted, stillborn and weak lambs from nine out of 42 flocks investigated during the 1980 and 1981 lambing seasons. Three serogroups of leptospira, namely the Hebdomadis, Australis and Pomona serogroups, were implicated. PMID- 6845608 CU - 91 SO - Vet Rec 1983 Mar 26;112(13):291-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 83253993 AU - Krivulis DB AU - Groshev AN AU - Burushkina TN AU - Aleinikov VG AU - Tsimermane GI TI - [Hemosorptive treatment of the terminal stage of hepatorenal insufficiency caused by leptospirosis] LA - Rus MH - English Abstract MH - *Hemoperfusion MH - Human MH - Kidney Failure, Acute/*therapy MH - Liver Diseases/*therapy MH - Weil's Disease/*therapy PT - JOURNAL ARTICLE DA - 830811 DP - 1983 Mar-Apr IS - 0201-7563 TA - Anesteziol Reanimatol PG - 35-9 CY - USSR IP - 2 JC - 4ST EM - 8310 PMID- 6869905 TT - Lechenie gemosorbtsiei terminal'noi stadii pechenochno-pochechnoi nedostatochnosti, vyzvannoi leptospirozom. EA - A SO - Anesteziol Reanimatol 1983 Mar-Apr;(2):35-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83251058 AU - Agba MI AU - King SD AU - Urquhart AE TI - Serological study of the distribution of Leptospira interrogans (serotype jules) and five other leptospires in Jamaica. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/microbiology MH - Goats/microbiology MH - Jamaica MH - Leptospira/*isolation & purification MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/*veterinary MH - Swine MH - Swine Diseases/microbiology MH - Weil's Disease/*veterinary PT - JOURNAL ARTICLE DA - 830811 DP - 1983 Mar IS - 0043-3144 TA - West Indian Med J PG - 32-7 CY - JAMAICA IP - 1 VI - 32 JC - XN4 EM - 8310 PMID- 6868569 SO - West Indian Med J 1983 Mar;32(1):32-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83243988 AU - Guelain J AU - Le Gonidec G AU - Bouchard E AU - Peghini M TI - [Leptospiroses in New Caledonia] LA - Fre MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Child MH - Child, Preschool MH - Climate MH - Economics MH - English Abstract MH - Ethnic Groups MH - Female MH - Geography MH - Human MH - Infant MH - Infant, Newborn MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - New Caledonia MH - Sex Factors MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 830826 DP - 1983 Mar-Apr IS - 0025-682X TA - Med Trop (Mars) PG - 137-43 SB - M CY - FRANCE IP - 2 VI - 43 JC - MHQ EM - 8310 PMID- 6865708 CU - 88 TT - Les leptospiroses en Nouvelle-Caledonie. EA - A SO - Med Trop (Mars) 1983 Mar-Apr;43(2):137-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83179761 AU - Andreani E AU - Tolari F AU - Farina R TI - Experimental infection in sheep with Leptospira interrogans serotype hardjo. LA - Eng MH - Abortion, Veterinary/etiology MH - Animal MH - Cattle MH - Cattle Diseases/microbiology MH - Female MH - Leptospira interrogans/isolation & purification/*pathogenicity MH - Male MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/veterinary MH - Septicemia/veterinary MH - Sheep MH - Sheep Diseases/*microbiology MH - Support, Non-U.S. Gov't MH - Weil's Disease/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 830617 DP - 1983 Mar-Apr IS - 0007-1935 TA - Br Vet J PG - 165-70 CY - ENGLAND IP - 2 VI - 139 JC - B5C EM - 8308 PMID- 6839124 SO - Br Vet J 1983 Mar-Apr;139(2):165-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83162874 AU - Harris LF AU - Frierson WB TI - Leptospirosis. LA - Eng MH - Adult MH - Case Report MH - Doxycycline/*analogs & derivatives/therapeutic use MH - Human MH - Leptospirosis/*diagnosis/drug therapy MH - Male MH - Middle Age MH - Penicillin G/therapeutic use MH - Serodiagnosis RN - 24390-14-5 (doxycycline hyclate) RN - 564-25-0 (Doxycycline) RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 830527 DP - 1983 Mar IS - 0025-7044 TA - J Med Assoc State Ala PG - 16-9 CY - UNITED STATES IP - 9 VI - 52 JC - IZJ EM - 8307 PMID- 6833904 SO - J Med Assoc State Ala 1983 Mar;52(9):16-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84017166 AU - Camargo MC AU - Figueiredo GM AU - Veneziani P AU - Oki S TI - [Leptospirosis] LA - Por MH - Hemagglutination Tests MH - Human MH - Leptospira/growth & development MH - *Leptospirosis MH - Penicillins/therapeutic use MH - Rodent Control MH - Weil's Disease RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 831123 DP - 1983 Mar-Apr IS - 0035-0362 TA - Rev Paul Med PG - 74-6 CY - BRAZIL IP - 2 VI - 101 JC - SZ5 EM - 8401 PMID- 6622897 CU - 92 TT - Leptospirose. SO - Rev Paul Med 1983 Mar-Apr;101(2):74-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 83303349 AU - Bezjak V AU - Thorburn H TI - Survey of rats (Rattus norvegicus) in Kuwait for the presence of Leptospira. LA - Eng MH - Animal MH - Kidney Cortex/microbiology MH - Kuwait MH - Leptospira interrogans/*isolation & purification MH - Rats/*microbiology PT - JOURNAL ARTICLE DA - 831008 DP - 1983 Mar IS - 0041-3232 TA - Trop Geogr Med PG - 33-6 SB - M CY - NETHERLANDS IP - 1 VI - 35 JC - WGJ AA - Author EM - 8312 AB - A survey of brown rats (Rattus norvegicus) was made in Kuwait in 1979 for the presence of Leptospira organisms. Kidney tissue from 49 rats, trapped mostly from various Kuwait City districts, were cultured on E.M.J.H. and Stuart media. Eight leptospira strains were isolated; all strains were identical and belonged to Leptospira interrogans Canicola serogroup; they were later identified as a new serovar kuwait. The frequency of L. interrogans group Canicola carriers among the local rats in Kuwait was 16.3%, which is higher than reported so far. A summary of published data on the isolation of Leptospira other than L. interrogans serogroup Icterohaemorrhagiae from rats, particularly the brown rat, is presented with emphasis on the Middle East. PMID- 6612771 SO - Trop Geogr Med 1983 Mar;35(1):33-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 84198653 AU - Hathaway SC AU - Little TW AU - Stevens AE TI - Identification of a reservoir of leptospira interrogans serovar muenchen in voles (Microtus agrestis and Clethrionomys glareolus) in England. LA - Eng MH - Agglutination Tests/methods MH - Animal MH - Disease Reservoirs/*veterinary MH - England MH - Leptospira interrogans/*classification/isolation & purification MH - Microtinae/*microbiology MH - Serotyping PT - JOURNAL ARTICLE DA - 840605 DP - 1983 Mar IS - 0174-3031 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 123-8 SB - M CY - GERMANY, WEST IP - 1 VI - 254 JC - Y5N AA - Author EM - 8408 AB - Infection with leptospires of the Australis serogroup is widespread in voles in Southern England and the serovar identification of five randomly-selected isolates was determined by cross agglutination absorption. Two isolates from short-tailed voles (Microtus agrestis) and three isolates from bank voles (Clethrionomys glareolus) were all identified as serovar muenchen. The only previous isolation of this serovar is that from a human in Germany. PMID- 6372316 CU - 90 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1983 Mar;254(1):123-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 83176507 AU - Frick OL AU - Brooks DL TI - Immunoglobulin E antibodies to pollens augmented in dogs by virus vaccines. LA - Eng MH - Adenoviruses, Canine/*immunology MH - Animal MH - Distemper Virus, Canine/*immunology MH - Dog Diseases/genetics/*immunology MH - Dogs MH - Hypersensitivity, Immediate/genetics/immunology/*veterinary MH - IgE/*biosynthesis MH - Intradermal Tests MH - Passive Cutaneous Anaphylaxis MH - Pollen/*immunology MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. MH - Vaccination/veterinary MH - Vaccines, Attenuated/immunology MH - Viral Vaccines/*immunology RN - 0 (Vaccines, Attenuated) RN - 0 (Viral Vaccines) RN - 37341-29-0 (IgE) PT - JOURNAL ARTICLE ID - R01-AI-15233/AI/NIAID DA - 830527 DP - 1983 Mar IS - 0002-9645 TA - Am J Vet Res PG - 440-5 SB - M CY - UNITED STATES IP - 3 VI - 44 JC - 40C AA - Author EM - 8307 AB - An inbred "atopic dog colony" was established to study the effect of viruses on immunoregulation of immunoglobulin (Ig) E antibodies. Dogs were selected for high skin reactivity to grass and weed pollens. Their offspring were inoculated with pollen extracts in alum immediately after routine vaccinations (attenuated live-virus vaccines for canine distemper and infectious canine hepatitis, and a killed bacterin for Leptospira). Heat labile antipollen IgE antibodies were measured by passive cutaneous anaphylaxis. Pups vaccinated for canine distemper before being given pollen extracts had many more IgE antibodies than did their control littermates who were not vaccinated until after the last pollen extract injection. This may be a natural example of the "allergic break-through phenomenon." PMID- 6301317 CU - 96 SO - Am J Vet Res 1983 Mar;44(3):440-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83180500 AU - Rak J TI - [Problems of standardizing the density of antigens for the Leptospira microagglutination test] LA - Slo MH - *Agglutination Tests MH - Antigens, Bacterial/*standards MH - English Abstract MH - Leptospira/*immunology MH - Nephelometry and Turbidimetry RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 830623 DP - 1983 Mar IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 63-7 CY - CZECHOSLOVAKIA IP - 2 VI - 32 JC - CSH EM - 8308 RO - M:BDS PMID- 6220821 LR - 850925 CU - 92 TT - K otazke standardizacie hustoty antigenov pre mikroaglutinacny test leptospir. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1983 Mar;32(2):63-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83172432 AU - Bercovich Z AU - Spek CW AU - Comvalius-Adriaan I TI - [The occurrence of antibodies to various Leptospira serotypes in swine in The Netherlands in the period 1975-1980] LA - Dut MH - Abortion, Veterinary/etiology MH - Animal MH - Antibodies, Bacterial/*isolation & purification MH - English Abstract MH - Female MH - Leptospira/*immunology MH - Leptospirosis/veterinary MH - Male MH - Pregnancy MH - Swine/*immunology MH - Swine Diseases/etiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830527 DP - 1983 Feb 15 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 133-8 SB - M CY - NETHERLANDS IP - 4 VI - 108 JC - VRY AA - Author EM - 8307 AB - A total number of 18.675 sera of pigs were examined for the presence of antibodies to various serotypes of Leptospira in the Netherlands during the period from 1975 to 1980. The study showed an average of 21 per cent of positive serological findings. The distribution of these findings amongst the various serotypes of Leptospira was as follows: L. bratislava 39%; L tarassovi 22%; L. ballum 15% and L. icterohaemorrhagiae 12%. The combined other serotypes scored approximately 12%. The percentage of serologically positive animals having a history of abortion was approximately 23%. 23% up to 1978. In 1979, it fell to 11%, and it increased again to 32% in 1980. The common serotypes of Leptospira in sows which aborted were L. bratislava, L. tarassovi, L. ballum and L. icterohaemorrhagiae. L. pomona, L. australis, L. canicola and L. hardjo were rare but were identified in a few cases. It is recommended that measures should be adopted to prevent the introduction of these serotypes. PMID- 6836549 CU - 91 TT - Het voorkomen van antilichamen tegen enkele Leptospira serotypen bij het varken in Nederland in de periode 1975-1980. EA - A SO - Tijdschr Diergeneeskd 1983 Feb 15;108(4):133-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83285279 AU - Zhang RZ TI - [Method of detection of incomplete antibody against Leptospira and its application] LA - Chi MH - Antibodies, Bacterial/*analysis MH - Coombs' Test MH - English Abstract MH - Hemagglutination Tests MH - Human MH - Leptospira/*immunology MH - Leptospirosis/diagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 831008 DP - 1983 Feb TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 15-7 CY - CHINA IP - 1 VI - 4 JC - CQG EM - 8312 PMID- 6883470 CU - 91 EA - A SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1983 Feb;4(1):15-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83190365 AU - Ugriumov BL AU - Pletnev VM AU - Vovk AD AU - Tat'ianko NV AU - Gorodetskii MM TI - [Clinical variants of leptospirosis] LA - Rus MH - Acute Disease MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Female MH - Human MH - Leptospirosis/classification/*diagnosis/physiopathology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 830610 DP - 1983 Feb IS - 0023-2149 TA - Klin Med (Mosk) PG - 89-93 CY - USSR IP - 2 VI - 61 JC - KW2 EM - 8308 PMID- 6843062 TT - Klinicheskie varianty leptospiroza. SO - Klin Med (Mosk) 1983 Feb;61(2):89-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83188120 AU - Neill SD AU - Reid LR AU - Ellis WA TI - Aminopeptidase activity of Leptospira strains. LA - Eng MH - Aminopeptidases/*metabolism MH - Leptospira/classification/*enzymology MH - Leptospira interrogans/enzymology MH - Naphthalenes/metabolism MH - Substrate Specificity RN - EC 3.4.11. (Aminopeptidases) RN - 0 (Naphthalenes) PT - JOURNAL ARTICLE DA - 830610 DP - 1983 Feb IS - 0022-1287 TA - J Gen Microbiol PG - 395-400 SB - M CY - ENGLAND VI - 129 (Pt 2) JC - I87 AA - Author EM - 8308 AB - A total of 15 cultures of Leptospira were examined for aminopeptidase activity using 22 aminoacyl-beta-naphthylamde substrates. Activity was demonstrated in each of the cultures. Extracts from serovars of Leptospira interrogans preferentially hydrolysed the same range of substrates. The level of hydrolysis of the preferred substrates for the seven strains of L. interrogans was distinctively higher than that demonstrated for the six Leptospira biflexa strains. Extracts from cultures of Leptospira illini and Leptospira parva sp. nov. exhibited profiles different to those demonstrated for the other 13 leptospiral cultures examined. RO - M:RMK PMID- 6842179 LR - 900720 CU - 91 SO - J Gen Microbiol 1983 Feb;129 (Pt 2):395-400 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83301359 AU - Cabrera Pupo L AU - Cornide Gonzalez RI AU - Romero Reyno J AU - Poutou Sanchez E TI - [Leptospirosis: serological report on the transient Haitian population in Cuba] LA - Spa MH - Agricultural Workers' Diseases/*epidemiology MH - Cuba MH - English Abstract MH - Haiti/ethnology MH - Human MH - Leptospirosis/*epidemiology MH - Serodiagnosis MH - *Transients and Migrants PT - JOURNAL ARTICLE DA - 831008 DP - 1983 Feb-Apr IS - 0375-0760 TA - Rev Cubana Med Trop PG - 112-8 CY - CUBA IP - 1 VI - 35 JC - RPX EM - 8312 PMID- 6351186 CU - 90 TT - Leptospirosis: informe serologico sobre la poblacion haitiana de transito en Cuba. EA - A SO - Rev Cubana Med Trop 1983 Feb-Apr;35(1):112-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83174376 AU - Soboleva GL TI - [Preparation and use of solid culture medium for Leptospira isolation] LA - Rus MH - *Culture Media MH - English Abstract MH - Leptospira/growth & development/*isolation & purification/pathogenicity MH - Microbiological Techniques MH - Serotyping MH - Virulence RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 830527 DP - 1983 Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 80-4 SB - M CY - USSR IP - 2 JC - Y9O AA - Author EM - 8307 AB - Recommendations on the preparation and use of a solid culture medium are given; age changes in the colonies of leptospires belonging to different serovars and serogroups have been studied in their dynamics; the absence of relationship between the form of the colonies, the serovar and serogroup of the cultures, their virulence, as well as the region, time and source of their isolation has been established, which makes it impossible to use these parameters for the differentiation of Leptospira strains belonging to different serovars on solid culture media. PMID- 6340396 CU - 91 TT - Prigotovlenie i primenenie plotnoi pitatel'noi sredy dlia raboty s leptospirami. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Feb;(2):80-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83174357 AU - Semenovich VN AU - Polotskii IuE TI - [Pathogenic properties of Leptospira in relation to the pathology of leptospirosis] LA - Rus MH - Animal MH - Hamsters MH - Human MH - Kidney/pathology MH - Leptospira interrogans/*pathogenicity MH - Leptospirosis/*microbiology/pathology MH - Liver/pathology MH - Virulence MH - Weil's Disease/microbiology/pathology PT - JOURNAL ARTICLE PT - REVIEW DA - 830527 DP - 1983 Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 13-7 SB - M CY - USSR IP - 2 JC - Y9O EM - 8307 RF - 48 PMID- 6340387 CU - 90 TT - Patogennye svoistva leptospir v sviazi s patologiei leptospiroza. SO - Zh Mikrobiol Epidemiol Immunobiol 1983 Feb;(2):13-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 83135299 AU - Stringfellow DA AU - Brown RR AU - Hanson LE AU - Schnurrenberger PR AU - Johnson J TI - Can antibody responses in cattle vaccinated with a multivalent leptospiral bacterin interfere with serologic diagnosis of disease? LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibody Formation MH - Bacterial Vaccines/analysis/*immunology MH - Cattle MH - Cattle Diseases/*diagnosis/immunology/prevention & control MH - Leptospira/immunology MH - Leptospirosis/immunology/*veterinary MH - Male MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Vaccination/*veterinary RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 830407 DP - 1983 Jan 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 165-7 SB - M CY - UNITED STATES IP - 2 VI - 182 JC - HAV AA - Author EM - 8306 AB - A commercially available leptospiral bacterin containing 5 serovars (canicola, grippotyphosa, hardjo, icterohemorrhagiae, pomona) was used per label directions to vaccinate 45 steers and bulls. In animals in which the prevaccination sera were negative for microscopic agglutinating antibody, the increase and decrease of titers were similar among all serovars. A serologic response was stimulated by a single dose and enhanced by the 2nd dose. Most titers peaked at 2 weeks and then fell rapidly by 15 weeks after the 2nd dose. Thirty-four animals with prevaccinal titers to serovar hardjo responded with high microscopic agglutinating titers for a sustained period. Of these cattle, 31 still had titers between 200 and 400 by 29 weeks after the 2nd dose. These results were interpreted as representing an anamnestic response initiated by the bacterin to a sensitization that had followed natural exposure. PMID- 6826435 CU - 91 SO - J Am Vet Med Assoc 1983 Jan 15;182(2):165-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 83282183 AU - Polotskii IuE AU - Semenovich VN AU - Komarova DV AU - Stoianova NA AU - Udalova GV TI - [Clinico-morphological characteristics of leptospirosis] LA - Rus MH - English Abstract MH - Human MH - Kidney/microbiology MH - Leptospira/*classification MH - Leptospirosis/*diagnosis/pathology MH - Liver/*microbiology/pathology MH - Male MH - Serodiagnosis MH - Serotyping MH - Spleen/microbiology PT - JOURNAL ARTICLE DA - 830923 DP - 1983 IS - 0004-1955 TA - Arkh Patol PG - 48-54 SB - M CY - USSR IP - 5 VI - 45 JC - 8OE AA - Author EM - 8311 AB - Observations in 5 patients dying with leptospirosis (at 6-30 days after the onset) caused by leptospira of the Hebdomadis serogroup are described. Bright jaundice developed due to severe serous liver centrilobular edema with pronounced dissociation of the liver cell bands, cholestasis, and cloudy swelling of hepatocytes. Albuminuria, oliguria, and uraemia were caused by acute tubular and interstitial nephritis. Hemorrhagic diathesis with small bleedings in the skin, mucous and serous membranes was associated with the impairment of permeability of microcirculatory vessels. Focal necroses of skeletal muscles, myocardiodystrophy, and focal myocarditis, serous leptomeningitis were also seen. Few leptospirae could be detected extracellularly (often attached to the outer host cell membranes) by Warthin-Starry's method of silver impregnation of paraffin sections and by indirect immunofluorescence, much more rarely could they be demonstrated by Levaditi's method of silver impregnation of pieces of the viscera. Most leptospirae were present in the liver in the case of death on the 6th day when no antibodies were yet present in the blood. Since the 9th day when the antibodies did appear, leptospirae gradually disappeared from the liver and were found in the kidneys. It is suggested that some leptospiral cytotoxic products play a role in the pathogenesis of leptospirosis. PMID- 6882242 TT - Kliniko-morfologicheskaia kharakteristika leptospiroza. EA - A SO - Arkh Patol 1983;45(5):48-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [69 medline neighbors] UI - 83277492 AU - Kolev V AU - Venev S AU - Markarian M AU - Dabev I TI - [Intrauterine bacterial and mycotic infections in cows] LA - Bul MH - Abortion, Veterinary/microbiology MH - Amniotic Fluid/microbiology MH - Animal MH - Bacterial Infections/microbiology/*veterinary MH - Cattle MH - Cattle Diseases/*microbiology MH - Comparative Study MH - Endometritis/microbiology/veterinary MH - English Abstract MH - Feces/microbiology MH - Female MH - Mycoses/microbiology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/*veterinary MH - Uterine Diseases/microbiology/*veterinary MH - Uterus/microbiology MH - Vagina/microbiology PT - JOURNAL ARTICLE DA - 830920 DP - 1983 IS - 0506-8215 TA - Vet Med Nauki PG - 33-40 SB - M CY - BULGARIA IP - 2 VI - 20 JC - XCE AA - Author EM - 8311 AB - Bacteriologic, mycologic, and serologic investigations of cows and calves and three experiments with rabbits were carried out to shed light on the bacteriology and mycology of the intrauterine infections in cows. The following organisms were isolated from the investigated cows that exhibited disturbances in their reproduction, and had abortions, or gave birth to calves that were affected with diseases or died: Escherichia coli (17.84%), association of bacteria (7.64%); Vibrio genitalis (3.86%); Streptococcus sp. (2.78%); moulds (2.54%); Staphylococcus aureus (2.20%); Proteus sp. (1.62%); Staphylococcus epidermidis (1.39%); Pseudomonas aeruginosa (1.39%); Pasteurella multocida (0.11%). The serologic investigation of a total of 231 blood samples from cows that miscarried, gave birth to dead calves, or failed to conceive revealed that in 15.58 per cent there was vibriosis, and in 6.06 per cent--leptospirosis. Demonstrated was the etiologic link between cows with reproductive disturbances and diseased calves with regard to vibriosis and leptospirosis. The tests with rabbits were indicative of bacterial carriers (with special reference to the genitalia) up to the 60th day following infection. There were abortions, sterility, and death cases and the birth of unviable bunnies in the case of reproduced coital infections with Escherichia coli and Pseudomonas aeruginosa. PMID- 6880018 TT - Prouchvaniia vurkhu bakterialnite i mikotichnite intrauterinni infektsii pri kravi. EA - A SO - Vet Med Nauki 1983;20(2):33-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83271752 AU - Kucharska-Demczuk K TI - [Fluorescence method of evaluation of the lysosomes of the lymphoid cells of the cerebrospinal fluid in meningitis and meningism] LA - Pol MH - Adolescence MH - Adult MH - Aged MH - Cerebrospinal Fluid/*cytology MH - Comparative Study MH - English Abstract MH - Female MH - Herpes Zoster/cerebrospinal fluid MH - Human MH - Lymphocytes/*ultrastructure MH - Lysosomes/*ultrastructure MH - Male MH - Meningism/*cerebrospinal fluid MH - Meningitis/*cerebrospinal fluid MH - Meningitis, Meningococcal/cerebrospinal fluid MH - Meningitis, Pneumococcal/cerebrospinal fluid MH - Meningitis, Viral/cerebrospinal fluid MH - Microscopy, Fluorescence MH - Middle Age MH - Mumps/cerebrospinal fluid PT - JOURNAL ARTICLE DA - 830923 DP - 1983 Jan-Feb IS - 0028-3843 TA - Neurol Neurochir Pol PG - 25-31 SB - M CY - POLAND IP - 1 VI - 17 JC - NYF AA - Author EM - 8311 AB - The fluorescence method of Blume et al. was found to be useful for identification and morphological evaluation of lysosomes in cerebrospinal fluid cells. The investigations were carried out in 49 patients with viral and bacterial meningitis or meningismus. It was demonstrated that the CSF cells in most patients with purulent meningitis contained no fluorescent granules in an early stage of the disease before introduction of antibacterial therapy. These granules were found in CSF cells in cases of leptospirosis, viral meningitis and meningismus of various aetiology in acute stage of the disease and even in convalescence, and in purulent meningitis in convalescence. In bacterial meningitis large lysosomal granules were observed, and in viral meningitis these granules were small. The method visualizes easily bacteria (meningococci and pneumococci) in the cerebrospinal fluid. PMID- 6877497 TT - Fluorescencyjna ocena lizosomow komorek limfoidalnych plynu mozgowo- rdzeniowego w zapaleniach i podraznieniach opon mozgowo-rdzeniowych. EA - A SO - Neurol Neurochir Pol 1983 Jan-Feb;17(1):25-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83250920 AU - Tarasov VI AU - Gaidai AM AU - Panarin IuD TI - [Diagnosis of sporadic leptospirosis in adults] LA - Rus MH - Adult MH - Case Report MH - Human MH - Leptospira/classification MH - Leptospirosis/*diagnosis/transmission MH - Male MH - Serodiagnosis MH - Serotyping PT - JOURNAL ARTICLE DA - 830817 DP - 1983 Jan IS - 0049-6804 TA - Vrach Delo PG - 116-8 CY - USSR IP - 1 JC - XLS EM - 8310 PMID- 6868489 TT - O rasponznavanii sporadicheskogo leptospiroza u vzroslykh. SO - Vrach Delo 1983 Jan;(1):116-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 83229444 AU - Chan HL TI - Bacterial infections of the skin. II: cutaneous clues to systemic infections. LA - Eng MH - Bacterial Infections/*complications MH - Clostridium Infections/complications MH - Endocarditis, Bacterial/complications MH - Erythema Nodosum/etiology MH - Gonorrhea/complications MH - Human MH - Leptospirosis/complications MH - Meningococcal Infections/complications MH - Pseudomonas Infections/complications MH - Septicemia/complications MH - Skin Diseases/*etiology MH - Typhoid/complications PT - JOURNAL ARTICLE DA - 830708 DP - 1983 Jan IS - 0304-4602 TA - Ann Acad Med Singapore PG - 98-102 SB - M CY - SINGAPORE IP - 1 VI - 12 JC - 53F AA - Author EM - 8309 AB - Systemic bacterial infections often produce skin signs which are of help in the elucidation and evaluation of these diseases. This paper reviews some of such cutaneous clues, their occurrence, recognition and value. The following conditions are discussed: bacterial endocarditis, pseudomonas septicaemia, disseminated gonococcal infection, meningococcemia, clostridia infections, leptospirosis and typhoid fever. Bacterial causes of erythema nodosum are also considered. PMID- 6859803 SO - Ann Acad Med Singapore 1983 Jan;12(1):98-102 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 83170867 AU - Hathaway SC AU - Blackmore DK AU - Marshall RB TI - Leptospirosis and the maintenance host: a laboratory mouse model. LA - Eng MH - Age Factors MH - Animal MH - Comparative Study MH - *Disease Models, Animal MH - *Disease Reservoirs MH - Female MH - Host-Parasite Relations MH - Leptospira/pathogenicity MH - Leptospirosis/parasitology/transmission/*veterinary MH - Male MH - Mice/*parasitology MH - Rodent Diseases/parasitology/*transmission MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 830505 DP - 1983 Jan IS - 0034-5288 TA - Res Vet Sci PG - 82-9 SB - M CY - ENGLAND IP - 1 VI - 34 JC - R7D AA - Author EM - 8307 AB - A laboratory mouse model was used to investigate the criteria that have been suggested as differentiating between a maintenance host and an accidental host for a particular leptospiral serovar. The comparative studies were conducted with serovars ballum, pomona, balcanica and hardjo. The relative pathological response, ratio of serological to bacteriological prevalence, level of serological response, age- susceptibility to infection and demonstration of artificial intraspecies transmission were found to be inadequate criteria with which to differentiate maintenance and accidental hosts for a particular serovar. The demonstration of natural intraspecies transmission was considered to be the definitive criterion for differentiating such hosts. In the light of the results obtained from the laboratory mouse model and the results obtained from field studies, a maintenance host may be defined as an animal which is capable of acting as a natural source of leptospiral infection for its own species. A maintenance population may be defined as a population of a species of animal which acts as a continuous reservoir of a serovar in a specific ecosystem. PMID- 6836184 SO - Res Vet Sci 1983 Jan;34(1):82-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 83154921 AU - Miragliotta G AU - Fumarola D TI - In vitro effect of Leptospira icterohaemorrhagiae on human mononuclear leukocytes procoagulant activity: comparison of virulent with nonvirulent strain. LA - Eng MH - *Blood Coagulation MH - Cells, Cultured MH - Comparative Study MH - Human MH - Leptospira interrogans/*pathogenicity MH - Monocytes/*microbiology/physiology MH - Virulence PT - JOURNAL ARTICLE DA - 830527 DP - 1983 Jan IS - 0008-4050 TA - Can J Comp Med PG - 70-2 SB - M CY - CANADA IP - 1 VI - 47 JC - CI0 AA - Author EM - 8307 AB - The in vitro effect of a virulent and a nonvirulent strain of Leptospira interrogans serotype icterohaemorrhagiae on human peripheral mononuclear cells was investigated. After addition of bacteria to citrated whole blood the production of mononuclear cell procoagulant activity (tissue factor) was observed. Indeed mononuclear cells isolated from whole blood bacteria mixtures after prolonged incubation shortened the recalcification time of normal plasma. The virulent strain induced a significantly higher procoagulant activity than nonvirulent and this effect was dependent on the number of bacteria. The production of tissue factor, a potent trigger of blood coagulation, by Leptospira icterohaemorrhagiae could help to understand the mechanism(s) responsible for the activation of intravascular coagulation associated with leptospirosis. PMID- 6831307 SO - Can J Comp Med 1983 Jan;47(1):70-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83124879 AU - Badiola J AU - Thiermann AB AU - Cheville NF TI - Pathologic features of leptospirosis in hamsters caused by Leptospira interrogans serovars hardjo and szwajizak. LA - Eng MH - Animal MH - *Hamsters MH - Kidney/microbiology/pathology/ultrastructure MH - Leptospira interrogans/classification/isolation & purification MH - Mesocricetus MH - Microscopy, Electron MH - Rodent Diseases/microbiology/*pathology MH - Serotyping MH - Weil's Disease/microbiology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 830324 DP - 1983 Jan IS - 0002-9645 TA - Am J Vet Res PG - 91-9 SB - M CY - UNITED STATES IP - 1 VI - 44 JC - 40C EM - 8305 PMID- 6824231 CU - 90 SO - Am J Vet Res 1983 Jan;44(1):91-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83224889 AU - Ratnam S AU - Sundararaj T AU - Subramanian S TI - Serological evidence of leptospirosis in a human population following an outbreak of the disease in cattle. LA - Eng MH - Adolescence MH - Animal MH - Antibodies, Bacterial MH - Cattle MH - Cattle Diseases/epidemiology MH - Child MH - Child, Preschool MH - Disease Outbreaks/veterinary MH - Female MH - Human MH - India MH - Leptospira/immunology MH - Leptospirosis/epidemiology/*transmission/veterinary MH - Male RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830708 DP - 1983 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 94-8 SB - M CY - ENGLAND IP - 1 VI - 77 JC - WBU AA - Author EM - 8309 AB - A serological study of leptospirosis in a human population, mainly children of a village near Madras City in Tamilnadu State, India, was undertaken following an outbreak of the disease in cattle as evidenced by clinical symptoms and serology. 27 (68%) of the 40 animal sera tested were positive for leptospiral antibodies. Though cross reactions were present, higher titres and a greater number of positive reactions were seen against autumnalis antigen. 35 (47%) of the 75 human sera gave positive antibody titres and, of these, 22 showed the presence of antibodies to autumnalis antigen. PMID- 6679368 CU - 91 SO - Trans R Soc Trop Med Hyg 1983;77(1):94-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 84153359 AU - Frolov AF AU - Barshtein IuA AU - Anisimova IuN TI - [Pathomorphology of toxico-infectious shock in influenza and leptospirosis] LA - Rus MH - Animal MH - Brain/blood supply MH - Coronary Vessels/pathology MH - English Abstract MH - Female MH - Human MH - Influenza/*complications MH - Kidney/blood supply MH - Liver/blood supply MH - Lung/blood supply MH - Male MH - Mice MH - Mice, Inbred CBA MH - Microcirculation/*pathology MH - Shock/etiology/*pathology MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 840406 DP - 1983 IS - 0004-1955 TA - Arkh Patol PG - 44-51 SB - M CY - USSR IP - 12 VI - 45 JC - 8OE AA - Author EM - 8406 AB - Examinations of the section material of fatal cases due to leptospirosis and influenza, as well as examinations of organs in experimental toxic influenza by light and electron microscopy with determinations of the infectious and immune complexes showed leptospira and influenza virus to be capable of causing toxico-infectious shock (TIS) with typical changes in the microcirculatory bed and organ parenchyma. TIS should be considered to be a special form of the course of an infectious process in which different organs may be "shock organs" depending on the tropic properties of the causative agent: in leptospirosis - the kidneys and liver, in influenza - the lungs and brain. PMID- 6670945 TT - Patomorfologiia toksiko-infektsionnogo shoka pri grippe i leptospiroze. EA - A SO - Arkh Patol 1983;45(12):44-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84147845 AU - Zhogolev KD AU - Stoianova NA TI - [Prospects of using the immunoadhesive hemagglutination reaction for leptospirosis diagnosis] LA - Rus MH - Agglutination Tests MH - Antigens, Bacterial/analysis MH - Comparative Study MH - Cross Reactions MH - English Abstract MH - Hemagglutination Tests/methods MH - Human MH - Immune Adherence Reaction/methods MH - Leptospira/immunology MH - Leptospirosis/*diagnosis RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 840406 DP - 1983 IS - 0202-1447 TA - Tr Inst Pastera PG - 119-23 CY - USSR VI - 60 JC - VZG EM - 8406 PMID- 6670105 CU - 91 TT - Perspektivy ispol'zovaniia reaktsii immunoadgezivnoi gemaggliutinatsii dlia diagnostiki leptospiroza. EA - A SO - Tr Inst Pastera 1983;60:119-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [70 medline neighbors] UI - 84109718 AU - Sebek Z AU - Vlcek M AU - Sterba J TI - Small mammals as reservoirs and transmitters of leptospires in livestock-breeding farms and their surroundings. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Disease Reservoirs/*veterinary MH - Leptospirosis/transmission/*veterinary MH - Mammals/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 840227 DP - 1983 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 363-71 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 30 JC - F2T AA - Author EM - 8405 AB - From 1976 to 1978, we examined 1723 wild small mammals, representing 15 species, from three animal production farms and their surroundings in the Trebon basin, south Bohemia, in order to detect antibodies against leptospirosis. Antibodies were found against the serovars grippotyphosa, sorex-jalna, sejroe and/or istrica. The serological positivity was higher in wet grassland stands and fields bordering fishponds. The dominant serovar was grippotyphosa against which antibodies were detected in 8 species of exoanthropic and synanthropic mammals. Owing to the wide ecological valence of the main natural reservoir of L. grippotyphosa--Microtus arvalis, this serovar was present even within the confines of the farms. M. arvalis, together with Apodemus sylvaticus, entering the farm buildings in the cold winter months, can introduce the serovar to the stables housing the farm animals. PMID- 6662412 CU - 91 SO - Folia Parasitol (Praha) 1983;30(4):363-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84097810 AU - Ugriumov BL AU - Frolov AF AU - Bernasovskaia EP TI - [Current problems with leptospirosis] LA - Rus MH - Adult MH - Female MH - Human MH - Leptospirosis/*prevention & control MH - Male MH - Middle Age MH - Seasons MH - Ukraine PT - JOURNAL ARTICLE DA - 840224 DP - 1983 IS - 0038-5077 TA - Sov Med PG - 108-11 CY - USSR IP - 10 JC - UW7 EM - 8404 PMID- 6658533 TT - Aktual'nye voprosy leptospiroza. SO - Sov Med 1983;(10):108-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 84067526 AU - Yanagihara Y AU - Kamisango K AU - Takeda K AU - Mifuchi I AU - Azuma I TI - Identification of 4-O-methylmannose in cell wall polysaccharide of Leptospira. LA - Eng MH - Cell Wall/analysis MH - Chemistry MH - Chromatography, Gas MH - Leptospira/*analysis/ultrastructure MH - Methylglycosides/*analysis MH - Methylmannosides/*analysis MH - Polysaccharides, Bacterial/*analysis MH - Spectrum Analysis, Mass RN - 0 (Methylglycosides) RN - 0 (Methylmannosides) RN - 0 (Polysaccharides, Bacterial) PT - JOURNAL ARTICLE DA - 840107 DP - 1983 IS - 0385-5600 TA - Microbiol Immunol PG - 711-5 SB - M CY - JAPAN IP - 8 VI - 27 JC - MX7 EM - 8403 PMID- 6645985 CU - 92 SO - Microbiol Immunol 1983;27(8):711-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84046105 AU - Ratnam S AU - Subramanian S AU - Madanagopalan N AU - Sundararaj T AU - Jayanthi V TI - Isolation of leptospires and demonstration of antibodies in human leptospirosis in Madras, India. LA - Eng MH - Antibodies, Bacterial/analysis MH - Blood/microbiology MH - Female MH - Human MH - India MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*diagnosis/immunology/microbiology MH - Male MH - Urine/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 831217 DP - 1983 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 455-8 SB - M CY - ENGLAND IP - 4 VI - 77 JC - WBU AA - Author EM - 8402 AB - Among 25 clinically suspected cases of leptospirosis, organisms could be isolated from blood and urine of only 10 cases but demonstrated in 15 cases. Antibody titres at a low level were observed to one or more leptospiral antigens in all 25 cases. Nine of the repeated samples from 12 cases showed a four-fold rise in titre. The highest antibody titres were seen against autumnalis. The predominant clinical picture was of fever, myalgia, conjunctival suffusion and jaundice with renal involvement. PMID- 6636272 CU - 91 SO - Trans R Soc Trop Med Hyg 1983;77(4):455-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [80 medline neighbors] UI - 84040818 AU - Gutman I AU - Walsh JB AU - Knapp AB TI - Cotton-wool spots as a sign in leptospirosis (Weil's disease). LA - Eng MH - Adult MH - Case Report MH - Conjunctival Diseases/diagnosis/etiology MH - Diagnosis, Differential MH - Hemorrhage/diagnosis/etiology MH - Human MH - Leptospira interrogans/isolation & purification MH - Male MH - Retinal Diseases/diagnosis/*etiology MH - Uveitis/diagnosis/etiology MH - Weil's Disease/complications/*diagnosis PT - JOURNAL ARTICLE DA - 831220 DP - 1983 IS - 0030-3755 TA - Ophthalmologica PG - 133-6 SB - M CY - SWITZERLAND IP - 3 VI - 187 JC - OIG AA - Author EM - 8402 AB - A 44-year-old black male presented with fever, myalgia and weakness. He had elevated blood urea nitrogen, creatine phosphokinase and serum glutamic-oxaloacetic transaminase. During the first 6 days of this undiagnosed illness azotemia increased, a pericardial friction rub occurred, and hematuria was present. On the 7th day bilateral subconjunctival hemorrhages, anterior uveitis, and peripapillary cotton- wool spots were noted. This combination of findings suggested leptospirosis, which was subsequently confirmed by specific antibody titers. Therapeutic response was achieved with high-dose systemic steroids. PMID- 6634059 SO - Ophthalmologica 1983;187(3):133-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 84030245 AU - Sebek Z AU - Treml F AU - Valova M TI - Experimental infection with the virulent, Central-European, murine Leptospira pomona strain in the pig. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Europe, Eastern MH - Leptospira/immunology/*pathogenicity MH - Leptospirosis/immunology/*microbiology MH - Muridae/*microbiology MH - Swine MH - Swine Diseases/immunology/*microbiology MH - Time Factors MH - Virulence RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 831220 DP - 1983 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 269-75 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 30 JC - F2T AA - Author EM - 8402 AB - The virulent, murine Leptospira pomona strain isolated from Apodemus agrarius was used in an experimental infection of six pigs aged 4--5 months. The clinical course of the infection was inapparent, both the blood picture and the uptake of food were normal. All infected pigs produced antibodies against L. pomona at titres from 1:3 200 to 1:50 000. The reisolation of leptospires from the blood of the infected pigs was successful in one case only, and that on day two p.i. Throughout the course of our experiment, no microscopic evidence was obtained of the presence of leptospires in the blood of the infected animals. Of the six guinea pigs injected repeatedly with the urine of the infected pigs, antibodies against L. pomona were detected in two of these at titres 1:3 200 and 1:6 400. However, no direct proof was obtained of leptospires in their kidneys. Leptospires were isolated from the kidneys of two of the infected pigs, at days 10 and 21 p.i. respectively. As suggested by our results, the Central European, murine Leptospira pomona strain should be regarded as an independent biovar incapable of causing a long-term leptospiruria and, hence, apparently unable to result in an epizooty in intensive pig husbandry. According to experimental evidence, Mus musculus can be a potential reservoir of the murine L. pomona biovar in Central Europe. PMID- 6629206 CU - 91 SO - Folia Parasitol (Praha) 1983;30(3):269-75 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83301218 AU - Anusz Z TI - [Brucellosis and other zoonoses - 1981. Human brucellosis] LA - Pol MH - Adult MH - Aged MH - Animal MH - Brucellosis/*epidemiology/transmission/veterinary MH - Cattle MH - Cattle Diseases/transmission MH - Comparative Study MH - Erysipeloid/epidemiology MH - Female MH - Human MH - Leptospirosis/epidemiology MH - Male MH - Middle Age MH - Occupational Diseases/epidemiology MH - Poland MH - Seasons MH - Sex Factors MH - Toxoplasmosis/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 831021 DP - 1983 IS - 0033-2100 TA - Przegl Epidemiol PG - 157-68 CY - POLAND IP - 1 VI - 37 JC - Q8T EM - 8312 PMID- 6611975 CU - 88 TT - Bruceloza i inne choroby odzwierzece - 1981 rok. Bruceloza ludzi. SO - Przegl Epidemiol 1983;37(1):157-68 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 84013017 AU - Vainrub B TI - Bacterial infections of the liver and biliary tract: laboratory studies to determine etiology. LA - Eng MH - Bacterial Infections/*diagnosis MH - Biliary Tract Diseases/*etiology MH - Brucellosis/diagnosis MH - Gonorrhea/diagnosis MH - Human MH - Legionnaires' Disease/diagnosis MH - Leptospirosis/diagnosis MH - Liver Abscess/diagnosis MH - Liver Diseases/*etiology MH - Paratyphoid Fever/diagnosis MH - Q Fever/diagnosis MH - Rocky Mountain Spotted Fever/diagnosis MH - Syphilis/diagnosis MH - Tuberculosis, Hepatic/diagnosis MH - Tularemia/diagnosis MH - Typhoid/diagnosis PT - JOURNAL ARTICLE PT - REVIEW DA - 831123 DP - 1983 TA - Lab Res Methods Biol Med PG - 119-28 SB - M CY - UNITED STATES VI - 7 JC - L2V EM - 8401 RF - 27 PMID- 6413797 CU - 91 SO - Lab Res Methods Biol Med 1983;7:119-28 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 90135397 AU - Nadazdin M AU - Seric K AU - Lucic N TI - [Electron microscopy study of Leptospira previously treated with antibodies in a microscopy agglutination test] LA - Scr MH - Agglutination Tests MH - Antibodies, Bacterial/*pharmacology MH - English Abstract MH - Leptospira/immunology/*ultrastructure RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 900315 DP - 1983 IS - 0025-8083 TA - Med Arh PG - 119-23 CY - YUGOSLAVIA IP - 3 VI - 37 JC - LNY EM - 9005 PMID- 6400845 CU - 91 NP - X TT - Elektronskomikroskopsko ispitivanje leptospira prethodno tretiranih antitjelima u testu mikroskopske aglutinacije. EA - A SO - Med Arh 1983;37(3):119-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [35 medline neighbors] UI - 83169233 AU - Goscienski PJ TI - Zoonoses. LA - Eng MH - Animal MH - Campylobacter Infections MH - Cat-Scratch Disease MH - Cestode Infections MH - Child MH - Chlamydia Infections MH - Cryptococcosis MH - Dermatomycoses MH - Dirofilariasis MH - Histoplasmosis MH - Human MH - Leptospirosis MH - Lymphocytic Choriomeningitis MH - Pasteurella Infections MH - Plague MH - Q Fever MH - Rabies MH - Salmonella Infections MH - Streptococcal Infections MH - Toxocariasis MH - Toxoplasmosis MH - Tuberculosis/transmission MH - Tularemia MH - Yersinia enterocolitica MH - Yersinia Infections MH - *Zoonoses/diagnosis/prevention & control/therapy/transmission PT - JOURNAL ARTICLE PT - REVIEW DA - 830505 DP - 1983 Jan-Feb IS - 0277-9730 TA - Pediatr Infect Dis PG - 69-81 SB - M CY - UNITED STATES IP - 1 VI - 2 JC - PA4 AA - Author EM - 8307 AB - Animal-transmitted diseases are remarkable not because they occur frequently but because they are almost always unsuspected and unrecognized. The physician who attends an ill veterinarian or zookeeper will immediately suspect an exotic disease. The pediatrician who attends the child who recently received a puppy for his birthday will not. Our public attitude toward animals as carriers of disease is utterly thoughtless. If a human were to urinate and defecate in the street or park he would be incarcerated without delay. Yet we tolerate and even encourage the same activity in dogs, which are known to carry scores of diseases to humans. Animals as pets are here to stay. Children are their frequent companions. It would serve all those who deal with the medical problems of children to know as much as possible about the diseases carried by animals, for their consequences are quite significant. RF - 112 PMID- 6340080 CU - 90 SO - Pediatr Infect Dis 1983 Jan-Feb;2(1):69-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83130410 AU - Biancifiori F AU - Cardaras P TI - Enzyme-linked immunoassay in the diagnosis of leptospirosis in domestic animals using peroxidase-conjugated protein-A. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Dog Diseases/*diagnosis MH - Dogs MH - Enzyme-Linked Immunosorbent Assay MH - Immunization MH - Isoenzymes MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/immunology/*veterinary MH - Peroxidases MH - Rabbits MH - Staphylococcal Protein A MH - Swine MH - Swine Diseases/*diagnosis RN - EC 1.11.1. (Peroxidases) RN - EC 1.11.1.7 (Peroxidase) RN - 0 (Antibodies, Bacterial) RN - 0 (Isoenzymes) PT - JOURNAL ARTICLE DA - 830415 DP - 1983 IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 57-65 SB - M CY - ENGLAND IP - 1 VI - 6 JC - DNN AA - Author EM - 8306 AB - The ELISA test for detection of antibodies to Leptospirosis in domestic animals was performed using Staphylococcal protein-A coupled to peroxidase in place of antisera to IgG. Genus- and type-specific antigens were extracted with SDS technique from four pathogenic serotypes and two non-pathogenic ones, and they were identified with the aid of ELISA using specific rabbit antisera. Micro-agglutination (MA) and ELISA were compared using a total of 48 positive swine sera and a 100% agreement was obtained, since with sera from 16 dogs clinically suspected of Leptospirosis the ELISA resulted highly more sensitive and precocious than MA in detecting specific antibodies. PMID- 6297847 CU - 93 SO - Comp Immunol Microbiol Infect Dis 1983;6(1):57-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84147857 AU - Tokarevich KN AU - Daiter AB TI - [Zooanthroponotic infections in the Northwest (I. Leptospirosis, Q rickettsiosis, pseudotuberculosis and tularemia)] LA - Rus MH - Animal MH - Animals, Wild MH - Disease Reservoirs MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Q Fever/*epidemiology MH - Research MH - Russia MH - Tularemia/*epidemiology MH - Yersinia pseudotuberculosis Infections/*epidemiology MH - Yersinia Infections/*epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 840406 DP - 1983 IS - 0202-1447 TA - Tr Inst Pastera PG - 4-14 CY - USSR VI - 60 JC - VZG EM - 8406 PMID- 6230772 CU - 92 TT - Zooantroponoznye infektsii na Severo-Zapade (ocherk I. Leptospiroz, Ku- rikketsioz, psevdotuberkulez, tuliaremiia). EA - A SO - Tr Inst Pastera 1983;60:4-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84147844 AU - Selezneva DA AU - Sosnitskii VI AU - Neverova NV AU - Snegirev VI AU - Ponomareva NA TI - [Leptospirosis in Arkhangelsk] LA - Rus MH - Animal MH - Animals, Domestic/microbiology MH - Disease Vectors MH - Dogs MH - English Abstract MH - Human MH - Leptospira/classification MH - Leptospirosis/*epidemiology/microbiology/transmission MH - Muridae/microbiology MH - Russia MH - Serotyping PT - JOURNAL ARTICLE DA - 840406 DP - 1983 IS - 0202-1447 TA - Tr Inst Pastera PG - 117-9 CY - USSR VI - 60 JC - VZG EM - 8406 PMID- 6230764 CU - 92 TT - Leptospiroz v Arkhangel'ske. EA - A SO - Tr Inst Pastera 1983;60:117-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84147843 AU - Skritskii VS AU - Kuznetsov GG TI - [Leptospirosis in Vologda Province] LA - Rus MH - Adolescence MH - Adult MH - Age Factors MH - Animal MH - Child MH - Disease Reservoirs MH - English Abstract MH - Female MH - Geography MH - Human MH - Leptospirosis/*epidemiology/etiology/transmission MH - Male MH - Middle Age MH - Rural Population MH - Russia MH - Sex Factors MH - Socioeconomic Factors MH - Zoonoses/transmission PT - JOURNAL ARTICLE DA - 840406 DP - 1983 IS - 0202-1447 TA - Tr Inst Pastera PG - 111-7 CY - USSR VI - 60 JC - VZG EM - 8406 PMID- 6230763 CU - 92 TT - Leptospiroz v Vologodskoi oblasti. EA - A SO - Tr Inst Pastera 1983;60:111-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 84147842 AU - Stoianova NA AU - Popova EM AU - Semenovich VN AU - Sergeiko LM AU - Udalova GV TI - [Leptospira infection in Leningrad] LA - Rus MH - Adult MH - English Abstract MH - Female MH - Human MH - Leptospirosis/diagnosis/*epidemiology/etiology MH - Male MH - Middle Age MH - Russia MH - Serodiagnosis MH - *Urban Population MH - Weil's Disease/diagnosis/epidemiology/etiology PT - JOURNAL ARTICLE DA - 840406 DP - 1983 IS - 0202-1447 TA - Tr Inst Pastera PG - 105-11 CY - USSR VI - 60 JC - VZG EM - 8406 PMID- 6230762 CU - 92 TT - Leptospiroznaia infektsiia v Leningrade. EA - A SO - Tr Inst Pastera 1983;60:105-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84189767 AU - Shubich MG AU - Primachenko NB AU - Lebedev VV TI - [Neutrophil alkaline phosphatase in the differential diagnosis of leptospirosis] LA - Rus MH - Alkaline Phosphatase/*blood MH - Diagnosis, Differential MH - Hepatitis, Viral, Human/enzymology MH - Human MH - Influenza/enzymology MH - Leptospirosis/*enzymology MH - Neutrophils/*enzymology RN - EC 3.1.3.1 (Alkaline Phosphatase) PT - JOURNAL ARTICLE DA - 840612 DP - 1983 IS - 0023-6748 TA - Lab Delo PG - 54-5 CY - USSR IP - 12 JC - KYU EM - 8408 PMID- 6201670 CU - 95 TT - Shchelochnaia fosfataza neitrofilov v differentsial'noi diagnostike leptospiroza. SO - Lab Delo 1983;(12):54-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 84157692 AU - Mazzonelli J AU - Dorta de Mazzonelli GT AU - Mailloux M TI - About the presence of a thermolabile (TL) antigenic fraction in Leptospira interrogans. LA - Eng MH - *Antigens, Bacterial/immunology MH - Epitopes MH - Heat MH - Leptospira interrogans/*immunology MH - Neutralization Tests RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 840510 DP - 1983 IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 339-43 SB - M CY - ENGLAND IP - 4 VI - 6 JC - DNN AA - Author EM - 8407 AB - Antisera prepared with living serovars of Leptospira interrogans have a fraction anti-TL able to neutralize TL antigen of Leptospira strains. After neutralization, any leptospiral serovar is able to adsorb heterologous antisera prepared with living strains. PMID- 6200266 CU - 95 SO - Comp Immunol Microbiol Infect Dis 1983;6(4):339-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84147853 AU - Boruta VV AU - Usova VS AU - Tkachenko VI AU - Miasnikov IuA AU - Tkachenko EA TI - [Hemorrhagic fever with renal syndrome and leptospirosis in the territory of Vladimir Province (preliminary report)] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/diagnosis MH - Diagnosis, Differential MH - Disease Reservoirs/veterinary MH - English Abstract MH - Hemorrhagic Fever with Renal Syndrome/*diagnosis/veterinary MH - Human MH - Leptospirosis/*diagnosis/veterinary MH - Rodent Diseases/diagnosis MH - Rodentia MH - Russia MH - Swine MH - Swine Diseases/diagnosis PT - JOURNAL ARTICLE DA - 840406 DP - 1983 IS - 0202-1447 TA - Tr Inst Pastera PG - 28-30 CY - USSR VI - 60 JC - VZG EM - 8406 PMID- 6142548 CU - 94 TT - Gemorragicheskaia likhoradka s pochechnym sindromom i leptospiroz na territorii Vladimirskoi oblasti (predvaritel'noe soobshchenie). EA - A SO - Tr Inst Pastera 1983;60:28-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 83142821 AU - Fuzi M TI - [In vitro bacteriostatic effect of current antibiotics on pathogenic Leptospirae] LA - Hun MH - Antibiotics/administration & dosage/*pharmacology MH - Culture Media MH - Dose-Response Relationship, Drug MH - Leptospira/*drug effects/pathogenicity MH - Microbial Sensitivity Tests RN - 0 (Antibiotics) RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 830407 DP - 1982 Dec 19 IS - 0030-6002 TA - Orv Hetil PG - 3131-2 CY - HUNGARY IP - 51 VI - 123 JC - OL8 EM - 8306 PMID- 7162803 CU - 91 TT - Ujabb antibiotikumok in vitro bakteriosztatikus hatasa pathogen leptospirakra. SO - Orv Hetil 1982 Dec 19;123(51):3131-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83135279 AU - Hanson LE TI - Leptospirosis in domestic animals: the public health perspective. LA - Eng MH - Animal MH - *Animals, Domestic MH - Animals, Wild MH - Disease Reservoirs/veterinary MH - Human MH - Leptospirosis/diagnosis/epidemiology/prevention & control/transmission/*veterinary MH - *Public Health MH - Risk MH - Species Specificity MH - United States MH - *Zoonoses PT - JOURNAL ARTICLE PT - REVIEW DA - 830407 DP - 1982 Dec 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1505-9 SB - M CY - UNITED STATES IP - 12 VI - 181 JC - HAV EM - 8306 RF - 44 PMID- 6761326 CU - 90 SO - J Am Vet Med Assoc 1982 Dec 15;181(12):1505-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 83061519 AU - Wolfe MS AU - Calisher CH AU - McGuire K TI - Spondweni virus infection in a foreign resident of Upper Volta. LA - Eng MH - Adult MH - Antibodies, Viral/analysis MH - Burkina Faso MH - Case Report MH - Culicidae/microbiology MH - Diagnosis, Differential MH - Flavivirus/immunology MH - Human MH - Insect Bites and Stings/microbiology MH - Male MH - Togaviridae Infections/*diagnosis/transmission MH - United States/ethnology RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 830119 DP - 1982 Dec 11 IS - 0140-6736 TA - Lancet PG - 1306-8 SB - A SB - M CY - ENGLAND IP - 8311 VI - 2 JC - L0S AA - Author EM - 8303 AB - Spondweni virus is a mosquito-borne flavivirus previously reported to cause human disease in Southern and West Africa. A serologically confirmed case of Spondweni virus infection in a U.S. citizen residing in Upper Volta is reported. Symptoms included fever, chills, headache, myalgia, nausea, and rash. A greyish mucoid lining was present on the posterior pharynx. The differential diagnosis included rickettsial infection, leptospirosis, typhoid fever, and numerous viral illnesses including Lassa fever. Evidence of Spondweni virus infection was also found in two other U.S. citizens residing in Gabon and Cameroon. Spondweni virus might be a cause of acute febrile illness throughout West Africa, and its presence should be considered in the differential diagnosis of febrile illness and in antibody surveys in that region. PMID- 6128599 CU - 94 SO - Lancet 1982 Dec 11;2(8311):1306-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [42 medline neighbors] UI - 83082345 AU - Ruppanner R AU - Jessup DA AU - Ohishi I AU - Behymer DE AU - Franti CE TI - Serologic survey for certain zoonotic diseases in black bears in California. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacterial Infections/epidemiology/*veterinary MH - *Carnivora/microbiology/parasitology MH - Parasitic Diseases/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830225 DP - 1982 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1288-91 SB - M CY - UNITED STATES IP - 11 VI - 181 JC - HAV AA - Author EM - 8304 AB - Black bears (Ursus americanus) from 3 geographic areas of California were tested for antibodies against agents of 6 zoonotic diseases: toxoplasmosis (indirect hemagglutination), Q fever (microagglutination), trichinosis (latex particle agglutination), botulism (passive hemagglutination), leptospirosis (plate agglutination), and plague (enzyme-linked immunosorbent assay). Of 149 sera tested, 40 (27%) were positive for Toxoplasma gondii antibodies and 25 (17%) had antibodies against Coxiella burnetii. Of 141 bears tested for Trichinella spiralis, 18 (13%) were seropositive, and 19 (15%) of 125 tested had antibodies against the plague organism, Yersinia pestis. Only 2% (2 of 123 tested) had antibodies against Clostridium botulinum. Sera from 129 bears were tested against 4 pools of Leptospira interrogans representing 12 serovars, and 16% of the sera reacted with the pool containing the serovars australis, hyos, and mini georgia. PMID- 7174445 CU - 91 SO - J Am Vet Med Assoc 1982 Dec 1;181(11):1288-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83185070 AU - Edelweiss EL AU - Mailloux M TI - Immunoglobulins in experimental leptospirosis in rabbits, and their relations with the results of the agglutination test. LA - Eng MH - Agglutination Tests/veterinary MH - Agglutinins/*analysis MH - Animal MH - Antibodies, Bacterial/analysis MH - Comparative Study MH - IgG/*analysis MH - IgM/*analysis MH - Leptospira interrogans/immunology MH - Rabbits/*immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/diagnosis/immunology/*veterinary RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830617 DP - 1982 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 79-86 SB - M CY - TAIWAN IP - 2 VI - 9 JC - GTK EM - 8308 PMID- 7169309 CU - 91 SO - Int J Zoonoses 1982 Dec;9(2):79-86 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83185068 AU - Jones CJ AU - Taylor KD AU - Myers DM AU - Turner LH AU - Everard CO TI - Pathogenic Leptospira isolates from the Caribbean Island of Barbados. LA - Eng MH - Animal MH - Barbados MH - Cattle MH - Dogs/microbiology MH - Human MH - Leptospira/*isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/microbiology/veterinary MH - Mice/microbiology MH - Mongoose/microbiology MH - Muridae/microbiology MH - Rats/microbiology MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 830617 DP - 1982 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 138-46 SB - M CY - TAIWAN IP - 2 VI - 9 JC - GTK EM - 8308 PMID- 7169308 CU - 90 SO - Int J Zoonoses 1982 Dec;9(2):138-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 83173542 AU - Adler B AU - Cousins DV AU - Faine S AU - Robertson GM TI - Bovine IgM and IgG response to Leptospira interrogans serovar hardjo as measured by enzyme immunoassay. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/diagnosis/*immunology MH - Enzyme-Linked Immunosorbent Assay MH - Female MH - IgG/*immunology MH - IgM/*immunology MH - Leptospira interrogans/*immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/diagnosis/immunology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830505 DP - 1982 Dec IS - 0378-1135 TA - Vet Microbiol PG - 577-85 SB - M CY - NETHERLANDS IP - 6 VI - 7 JC - XBW AA - Author EM - 8307 AB - The enzyme-linked immunosorbent assay (ELISA) was used to detect specific IgG and IgG antibodies in the sera of cattle infected or immunized with Leptospira interrogans serovar hardjo. IgM appeared first but was quickly followed by IgG which persisted longer than IgM. The levels of antibody detectable by ELISA and by the microscopic agglutination test (MAT) did not correlate, suggesting that the two techniques measured different antigen--antibody systems. The transient nature of the IgM response as measured by ELISA indicates potential usefulness as a serodiagnostic test for detecting current leptospiral infections. PMID- 7168135 CU - 91 SO - Vet Microbiol 1982 Dec;7(6):577-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 83173540 AU - Aycardi E AU - Rivera B AU - Torres B AU - De Bohorquez V TI - Experimental infection with a Leptospira hardjo strain isolated from cattle of the eastern plains of Colombia. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/immunology/*microbiology MH - Colombia MH - Female MH - Leptospira interrogans/immunology/isolation & purification/pathogenicity MH - Pregnancy MH - Pregnancy Complications, Infectious/immunology/microbiology/*veterinary MH - Species Specificity MH - Weil's Disease/immunology/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830505 DP - 1982 Dec IS - 0378-1135 TA - Vet Microbiol PG - 545-50 SB - M CY - NETHERLANDS IP - 6 VI - 7 JC - XBW AA - Author EM - 8307 AB - The infectivity and pathogenicity of a strain of Leptospira hardjo isolated from the eastern plains of Colombia were evaluated. Ten pregnant heifers were artifically inoculated and monitored during 10 months. During the trial, isolation of leptospires was attempted and antibodies were detected by the microscopic agglutination test. Leptospires were recovered from the urine of six of the inoculated animals up to 6 months after infection. Eight of ten calves born from the inoculated heifers were born weak, and one of them died 12 h after parturition. Three of the weak calves had generalized jaundice of the internal surfaces. Half of the cows developed metritis and had a retained placenta. Serological reactions were seen against serotypes other than L. hardjo. A chronic infection was apparently established in the inoculated heifers with leptospiruria resulting in reinfection of the animals and a secondary rise in antibody levels. PMID- 7168134 CU - 91 SO - Vet Microbiol 1982 Dec;7(6):545-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83148563 AU - Riedemann S AU - Zamora J TI - [Leptospirosis in small rodents in rural areas of Valdivia] LA - Spa MH - Animal MH - Chile MH - Female MH - Leptospirosis/blood/epidemiology/*veterinary MH - Male MH - Muridae/*blood MH - Rodent Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 830407 DP - 1982 Dec IS - 0514-7166 TA - Zentralbl Veterinarmed [B] PG - 764-8 CY - GERMANY, WEST IP - 10 VI - 29 JC - Y72 EM - 8306 PMID- 7164670 CU - 88 TT - Leptospirosis en pequenos roedores en el area rural de Valdivia. SO - Zentralbl Veterinarmed [B] 1982 Dec;29(10):764-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83147984 AU - Sharapova OK AU - Savchenko BI AU - Zubko VI AU - Tkachuk VV TI - [Clinico-epidemiologic characteristics of leptospirosis in the Odessa region] LA - Rus MH - Adolescence MH - Adult MH - Case Report MH - Diagnostic Errors MH - Female MH - Human MH - Leptospirosis/*diagnosis/epidemiology MH - Male MH - Ukraine PT - JOURNAL ARTICLE DA - 830407 DP - 1982 Dec IS - 0049-6804 TA - Vrach Delo PG - 95-7 CY - USSR IP - 12 JC - XLS EM - 8306 PMID- 7164397 CU - 88 TT - Kliniko-epidemiologicheskaia kharakteristika leptospiroza v Odesskoi oblasti. SO - Vrach Delo 1982 Dec;(12):95-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 83122091 AU - Lettau LA TI - Urban leptospirosis in Milwaukee. LA - Eng MH - Adult MH - Animal MH - Case Report MH - Disease Reservoirs MH - Human MH - Male MH - Rats/microbiology MH - Weil's Disease/*transmission MH - Wisconsin PT - JOURNAL ARTICLE DA - 830311 DP - 1982 Dec IS - 0043-6542 TA - Wis Med J PG - 23-4 CY - UNITED STATES IP - 12 VI - 81 JC - XPJ EM - 8305 PMID- 7157829 SO - Wis Med J 1982 Dec;81(12):23-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [54 medline neighbors] UI - 83082312 AU - Schoneweis DA AU - Henry SC TI - Theory and practice of immunoprophylaxis in swine. LA - Eng MH - Animal MH - Animals, Newborn MH - Bordetella Infections/immunology/prevention & control/veterinary MH - Brucellosis/immunology/prevention & control/veterinary MH - Clostridium Infections/immunology/prevention & control/veterinary MH - Dysentery/immunology/prevention & control/veterinary MH - Escherichia coli Infections/immunology/prevention & control/veterinary MH - Female MH - Gastroenteritis, Transmissible, of Swine/immunology/prevention & control MH - Haemophilus Infections/immunology/prevention & control/veterinary MH - Leptospirosis/immunology/prevention & control/veterinary MH - Parvoviridae MH - Pasteurella Infections/immunology/prevention & control/veterinary MH - Rotavirus Infections/immunology/prevention & control/veterinary MH - Salmonella Infections/immunology/prevention & control MH - Salmonella Infections, Animal MH - Swine MH - Swine Diseases/immunology/*prevention & control MH - Swine Erysipelas/immunology/prevention & control MH - Vaccination/*veterinary MH - Virus Diseases/immunology/prevention & control/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 830214 DP - 1982 Nov 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1154-7 SB - M CY - UNITED STATES IP - 10 VI - 181 JC - HAV EM - 8304 RF - 32 PMID- 6757217 CU - 90 SO - J Am Vet Med Assoc 1982 Nov 15;181(10):1154-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 83063452 AU - Biglino A AU - Caramello P AU - Pischedda P TI - [Protracted intrahepatic cholestasis with thrombocytosis in leptospirosis] LA - Ita MH - Adult MH - Case Report MH - Cholestasis, Intrahepatic/*etiology MH - English Abstract MH - Hepatomegaly/etiology MH - Human MH - Hydrocortisone/therapeutic use MH - Hypertension, Portal/etiology MH - Leptospirosis/*complications/drug therapy/pathology MH - Liver/pathology MH - Male MH - Penicillin G/therapeutic use MH - Splenomegaly/etiology MH - Thrombocytosis/*etiology RN - 50-23-7 (Hydrocortisone) RN - 61-33-6 (Penicillin G) PT - JOURNAL ARTICLE DA - 830107 DP - 1982 Nov 10 IS - 0026-4806 TA - Minerva Med PG - 3053-8 SB - M CY - ITALY IP - 43 VI - 73 JC - N6M EM - 8303 PMID- 7145181 TT - Colostasi intraepatica prolungata, con iperpiastrinemia, in corso di infezione da Leptospire. EA - A SO - Minerva Med 1982 Nov 10;73(43):3053-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83233922 AU - Wu CB TI - [Transient ischemic attacks in adolescence and childhood caused by cerebral leptospirotic arteritis--report of 8 cases] LA - Chi MH - Adolescence MH - Cerebral Arteries/pathology MH - Cerebral Artery Diseases/*complications MH - Cerebral Ischemia, Transient/diagnosis/*etiology MH - Child MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*complications MH - Male PT - JOURNAL ARTICLE DA - 830811 DP - 1982 Nov IS - 0412-4057 TA - Chung Hua Shen Ching Ching Shen Ko Tsa Chih PG - 225-7 CY - CHINA IP - 4 VI - 15 JC - D7Y EM - 8310 PMID- 7183433 EA - A SO - Chung Hua Shen Ching Ching Shen Ko Tsa Chih 1982 Nov;15(4):225-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 83085718 AU - Christopher WL AU - Adler B AU - Faine S TI - Immunogenicity of leptospiral vaccines grown in protein-free medium. LA - Eng MH - Agglutinins/analysis MH - Animal MH - Bacterial Vaccines/*immunology MH - Culture Media MH - Formaldehyde MH - Guinea Pigs MH - Leptospira/*immunology MH - Rabbits MH - Skin Tests MH - Support, Non-U.S. Gov't RN - 0 (Agglutinins) RN - 0 (Bacterial Vaccines) RN - 0 (Culture Media) RN - 50-00-0 (Formaldehyde) PT - JOURNAL ARTICLE DA - 830214 DP - 1982 Nov IS - 0022-2615 TA - J Med Microbiol PG - 493-501 SB - M CY - ENGLAND IP - 4 VI - 15 JC - J2N AA - Author EM - 8304 AB - Leptospira interrogans serovars pomona and hardjo were adapted to grow in a chemically-defined, protein-free (PF) medium. Formolised monovalent vaccines of serovars pomona and hardjo and a bivalent mixture of the two were prepared from PF cultures. Live PF cultures and the vaccine preparations retained their agglutinating antigens and their immunogenicity when tested in rabbits and guinea-pigs. The vaccines were not pyrogenic and dermal reactions were slight. PMID- 7175917 CU - 91 SO - J Med Microbiol 1982 Nov;15(4):493-501 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83155927 AU - Joseph-Louisia J AU - Mailloux M AU - Daguet GL TI - [Leptospiroses in New Caledonia. Reports of 32 cases diagnosed between 1973 and 1980] LA - Fre MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Child MH - English Abstract MH - Ethnic Groups MH - Female MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - New Caledonia MH - Sex Factors PT - JOURNAL ARTICLE DA - 830527 DP - 1982 Nov IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 461-5 SB - M CY - FRANCE IP - 5 VI - 75 JC - C4G AA - Author EM - 8307 AB - This first study about human leptospiroses in New Caledonia reports 32 cases diagnosed between 1973 and 1980. They are typical forms with hepatonephritis in 90 % of cases. Serogroup Icterohaemorrhagiae is predominating (75 %), followed by Canicola and Australis. The disease is spread throughout the whole territory with two foci in the suburbs of the main town where there are irrigated market gardens. Contamination is indirect by contact with water infected by rodents. PMID- 7165895 CU - 88 TT - Leptospiroses en Nouvelle-Caledonie. Bilan des case diagnostiques de 1973 a 1980. EA - A SO - Bull Soc Pathol Exot Filiales 1982 Nov;75(5):461-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83108060 AU - O'Neill PG AU - Christie M AU - Cahill J AU - Duffy B TI - Leptospirosis and renal failure--clinical experience over a one year period. LA - Eng MH - Adult MH - Aged MH - Human MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 830311 DP - 1982 Nov IS - 0021-1265 TA - Ir J Med Sci PG - 339-42 CY - IRELAND IP - 11 VI - 151 JC - GXB EM - 8305 PMID- 7152868 SO - Ir J Med Sci 1982 Nov;151(11):339-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 83072301 AU - Kahn JB TI - A case of Weil's disease requiring steroid therapy for thrombocytopenia and bleeding. LA - Eng MH - Adrenal Cortex Hormones/*therapeutic use MH - Adult MH - Animal MH - Case Report MH - Hemorrhage/complications/*drug therapy MH - Human MH - Male MH - Platelet Count MH - Thrombocytopenia/complications/*drug therapy MH - Weil's Disease/complications/diagnosis/*drug therapy RN - 0 (Adrenal Cortex Hormones) PT - JOURNAL ARTICLE DA - 830119 DP - 1982 Nov IS - 0002-9637 TA - Am J Trop Med Hyg PG - 1213-5 SB - A SB - M CY - UNITED STATES IP - 6 VI - 31 JC - 3ZQ AA - Author EM - 8303 AB - A young New Hampshire man was recently treated for severe Weil's disease caused by serologically diagnosed Leptospira icterohemorrhagiae. In addition to severe renal failure and hepatic disease, his case featured marked thrombocytopenia with multiple evidences of bleeding. A course of steroid therapy was associated with improved platelet counts and amelioration of his hemorrhagic diathesis. PMID- 7149105 CU - 91 SO - Am J Trop Med Hyg 1982 Nov;31(6):1213-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 83056473 AU - Bass EP AU - Gill MA AU - Beckenhauer WH TI - Development of a modified live, canine origin parvovirus vaccine. LA - Eng MH - Animal MH - Antibodies, Viral/analysis MH - Comparative Study MH - Dog Diseases/prevention & control MH - Dogs/*immunology MH - Parvoviridae/*immunology MH - Viral Vaccines/adverse effects/*immunology MH - Virulence MH - Virus Diseases/prevention & control/veterinary RN - 0 (Antibodies, Viral) RN - 0 (Viral Vaccines) PT - JOURNAL ARTICLE DA - 830119 DP - 1982 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 909-13 SB - M CY - UNITED STATES IP - 9 VI - 181 JC - HAV AA - Author EM - 8303 AB - A modified live, canine origin parvovirus vaccine was tested for safety, efficacy, and clinical performance. The vaccine protected dogs from challenge of immunity with canine parvovirus (CPV) that caused clinical illness in all nonvaccinated dogs. Vaccinates all developed CPV serum neutralization antibody titers, with a mean value of 1,664. Challenge virus was not isolated from vaccinates, but feces from nonvaccinated dogs were CPV-positive for up to 4 days following challenge. In a pathogenicity test, dogs inoculated orally with 10 times the label dose remained clinically normal. In a reversion-to- virulence test, the vaccine strain remained nonpathogenic through 6 passages in seronegative test dogs. An immunologic interference test demonstrated that test dogs developed antibodies for all antigens in a combined canine distemper virus-adenovirus 2-parainfluenza virus- parvovirus vaccine and a Leptospira interrogans serovars canicola and icterohaemorrhagiae bacterin. A total of 1,796 doses of the multivalent preparation was administered in a field study, with veterinary practitioners reporting 36 local and 5 generalized reactions. PMID- 7141990 CU - 92 SO - J Am Vet Med Assoc 1982 Nov 1;181(9):909-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 83098602 AU - Moorhouse PD AU - Hugh-Jones ME AU - Barta O AU - Swann AI TI - Leptospiral and brucellar titers in frozen bovine sera after 20 years of storage. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Blood Preservation/*veterinary MH - Brucella abortus/*immunology MH - Cattle/*immunology MH - Female MH - Freezing MH - Immune Sera/immunology MH - Leptospira interrogans/*immunology MH - Male MH - Time Factors RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830214 DP - 1982 Nov IS - 0002-9645 TA - Am J Vet Res PG - 2031-4 SB - M CY - UNITED STATES IP - 11 VI - 43 JC - 40C AA - Author EM - 8304 AB - Generally good agreement was obtained between the rankings of sera titers when originally tested (T1), and those of the same sera 20 years later (T2). At the later time, the majority of samples (88%) were in, or within 1 dilution factor of their classification at T1. Test results for Brucella abortus and Leptospira interrogans var pomona antibodies demonstrated that original titers, in the upper-lower limits of 20 to 50, had decreased over a wide range (20% to 90%), and the later tests show that the greater the original titer, the greater the proportional decrease. Thus, titers of 20,000 at T1 had decreased by 49% to 99% and those of 200,000, by 95% to 99.8%. Variations in T2 test results were noted between some samples which had given identical results at T1. A decrease in titer over time has been demonstrated. An estimate of the expected half-lives of sera of differing initial Leptospira antibody titers is that for each unit increase in log10 of the initial titer, the half-life is reduced by about 50%. The heterogeneity of the immune response is postulated as the reason for this variation. PMID- 6817674 CU - 91 SO - Am J Vet Res 1982 Nov;43(11):2031-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83148498 AU - Ueno K AU - Yanagawa R AU - Yepez-Plascencio W TI - Antigenic variants of leptospiras detected in peritoneal cavity in early stage of infection in immunized guinea pigs. LA - Eng MH - Animal MH - Antigens, Bacterial/*immunology MH - Ascitic Fluid/*microbiology MH - Epitopes MH - Female MH - Guinea Pigs MH - Immunization MH - Leptospira interrogans/genetics/*immunology MH - Precipitin Tests MH - Support, Non-U.S. Gov't MH - Time Factors MH - *Variation (Genetics) RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 830421 DP - 1982 Nov TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 247-52 SB - M CY - GERMANY, WEST IP - 2 VI - 253 JC - Y5N AA - Author EM - 8306 AB - Antigenic variants were detected firstly 7 h following intraperitoneal challenge with Leptospira interrogans serovar copenhageni Shibaura in the peritoneal cavity of guinea pigs which had been previously immunized with the homologous strain. The variants appeared at a rate of 63% of the leptospiras which survived in the peritoneal cavity, and the survivors' rate was 0.00005% of the inoculated organisms. The antigenicity of these variants reversed to that of the parent after 3-5 passages in liquid normal serum medium. PMID- 6187138 CU - 95 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1982 Nov;253(2):247-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 83275137 AU - Nicolcioiu M AU - Romosan I AU - Manescu N AU - Golea O AU - Georgescu L AU - Zosin C TI - [Acute renal insufficiency due to leptospirosis] LA - Rum MH - Adolescence MH - Adult MH - Aged MH - English Abstract MH - Female MH - Gastrointestinal Hemorrhage/etiology MH - Hemodialysis MH - Human MH - Kidney/pathology MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications/pathology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 830920 DP - 1982 Nov-Dec IS - 1220-0905 TA - Rev Med Interna Neurol Psihiatr Neurochir Dermatovenerol Med Intern PG - 545-52 CY - ROMANIA IP - 6 VI - 34 JC - SLG EM - 8311 PMID- 6136080 CU - 94 TT - Insuficienta renala acuta prin leptospiroza. EA - A SO - Rev Med Interna Neurol Psihiatr Neurochir Dermatovenerol Med Intern 1982 Nov-Dec;34(6):545-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83092352 AU - Chahud Isee A AU - Pichilingue Prieto O AU - Zegarra Ames C AU - Diaz Calderon A AU - Luna Alva T AU - Liceras de Hidalgo J TI - [Icteric leptospirosis. Clinico-pathologic study] LA - Spa MH - Adolescence MH - Adult MH - English Abstract MH - Human MH - Leptospira interrogans MH - Liver/*pathology MH - Middle Age MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 830225 DP - 1982 Oct 31 IS - 0014-2565 TA - Rev Clin Esp PG - 85-8 CY - SPAIN IP - 2 VI - 167 JC - RNL EM - 8304 PMID- 7178600 TT - Leptospirosis icterica. Estudio clinico-patologico. EA - A SO - Rev Clin Esp 1982 Oct 31;167(2):85-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83100172 AU - Kirkman DB AU - Campbell RS AU - Miller RI TI - Observations on equine leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Australia MH - Horse Diseases/immunology/*microbiology MH - Horses MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Support, Non-U.S. Gov't MH - Tropical Climate RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830225 DP - 1982 Oct IS - 0005-0423 TA - Aust Vet J PG - 124 SB - M CY - AUSTRALIA IP - 4 VI - 59 JC - 9IE EM - 8304 PMID- 7181781 CU - 91 SO - Aust Vet J 1982 Oct;59(4):124 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 83096006 AU - Ezhov GI AU - Artiushin SK AU - Lysenko AM TI - [Nucleotide composition and homology of the DNA of parasitic Leptospira] LA - Rus MH - Cross Reactions MH - DNA, Bacterial/*genetics/immunology MH - English Abstract MH - Leptospira/*genetics/immunology MH - Leptospira canicola/genetics/immunology MH - Nucleic Acid Hybridization MH - Nucleotides/*analysis/genetics RN - 0 (DNA, Bacterial) RN - 0 (Nucleotides) PT - JOURNAL ARTICLE DA - 830214 DP - 1982 Oct IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 47-8 SB - M CY - USSR IP - 10 JC - Y9O AA - Author EM - 8304 AB - The study of DNA in parasitic leptospirae of different serovariants by the method of molecular hybridization has revealed two groups differing in their homology level. The homology of nucleic acids has been found to correlate with serological properties. The serovariants ensuring cross immunity are characterized by the high level of homology of their DNA. PMID- 7180252 CU - 91 TT - Nukleotidnyi sostav i gomologiia DNK parazitarnykh leptospir. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1982 Oct;(10):47-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 83095608 AU - Thieler H AU - Schmidt U AU - Jung N AU - Anger G AU - Budde E AU - Giertler R AU - Kummritz H TI - [Leptospiroses with acute renal failure--report on 6 dialyzed patients] LA - Ger MH - Adult MH - Case Report MH - Diagnosis, Differential MH - English Abstract MH - *Hemodialysis MH - Human MH - Kidney Failure, Acute/diagnosis/*therapy MH - Leptospirosis/diagnosis/*therapy MH - Male MH - Middle Age MH - Weil's Disease/therapy PT - JOURNAL ARTICLE DA - 830214 DP - 1982 Oct 1 IS - 0044-2542 TA - Z Gesamte Inn Med PG - 644-9 SB - M CY - GERMANY, EAST IP - 19 VI - 37 JC - XUY AA - Author EM - 8304 AB - From 1968 to 1981 6 patients with severe leptospiroses were treated: one with leptospirosis icterohaemorrhagiae (Weil's disease), two with leptospirosis copenhageni and three with leptospirosis grippotyphosa. The diagnosis must at first clinically be made from exposition anamnesis and symptoms. In three patients the agglutination lysis reaction had a negative result still between the 10th and 19th day after the beginning of the disease. In all 6 cases a hypercatabolic acute renal failure with azothaemia of high degree was present. The polyuric phase developed 10 to 18 days after the beginning of the disease, the serum creatinine values normalized 20 to 35 days after the beginning of the disease. The parenteral nutrition and the dialysis therapy were particular points in the complex therapy of the patients. 4 patients were haemodialysed - 3 of them after primary peritoneal dialysis - 2 patients were only peritoneally dialysed. On account of the hypercatabolism and the intestinal paralysis the haemodialysis is to be preferred, as a rule, to the peritoneal dialysis. Also in the haemodialysis of patients with leptospirosis modern developments should be taken into consideration: bicarbonate-containing dialytic solution and in haemorrhagic diathesis the heparin-free dialysis. All 6 own patients survived. When connecting these data with other reports from Central and South Europe the lethality of dialysed cases with leptospirosis is about 42% (25 of the 59 patients died). In 4 of 5 of our patients with leptospirosis a clear hyperamylasaemia was present, apparently the expression of the involvement of the pancreas. PMID- 7180062 TT - Leptospirosen mit akutem Nierenversagen--Bericht uber 6 dialysierte Patienten. EA - A SO - Z Gesamte Inn Med 1982 Oct 1;37(19):644-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83148574 AU - Riedemann S AU - Zamora J TI - [Epidemiologic aspects of human leptospirosis in rural areas] LA - Spa MH - Chile MH - English Abstract MH - Female MH - Human MH - Leptospirosis/blood/*epidemiology MH - Male MH - Rural Population MH - Serotyping MH - Sex Factors PT - JOURNAL ARTICLE DA - 830407 DP - 1982 Oct IS - 0514-7166 TA - Zentralbl Veterinarmed [B] PG - 702-7 CY - GERMANY, WEST IP - 9 VI - 29 JC - Y72 EM - 8306 PMID- 7164675 CU - 88 TT - Aspectos epidemiologicos de leptospirosis humana en el medio rural. EA - A SO - Zentralbl Veterinarmed [B] 1982 Oct;29(9):702-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 83032822 AU - Davila de Arriaga AJ AU - Rocha AS AU - Yasuda PH AU - De Brito T TI - Morpho-functional patterns of kidney injury in the experimental leptospirosis of the guinea-pig (L. icterohaemorrhagiae). LA - Eng MH - Animal MH - Guinea Pigs MH - Kidney/physiopathology/*ultrastructure MH - Kidney Diseases/*etiology/*pathology/physiopathology MH - Kidney Function Tests MH - Kidney Glomerulus/ultrastructure MH - Kidney Tubules, Proximal/ultrastructure MH - Microscopy, Electron MH - Support, Non-U.S. Gov't MH - Weil's Disease/complications/*pathology/physiopathology PT - JOURNAL ARTICLE DA - 821216 DP - 1982 Oct IS - 0022-3417 TA - J Pathol PG - 145-61 SB - M CY - ENGLAND IP - 2 VI - 138 JC - JLB AA - Author EM - 8302 AB - Thirty-seven guinea-pigs experimentally infected with a virulent strain of L. icterohaemorrhagiae, were submitted to a renal function study as evaluated through the maximal urinary concentration (MUC) test, blood urea nitrogen (BUN) and afterwards had their kidneys examined by light and electron microscopy. Vascular changes were also studied after the administration of colloidal carbon as a marker. Through the MUC test and BUN determination, two groups of tubulo-interstitial lesions can be visualised, one in animals without renal sufficiency, manifested chiefly by cell edema with RE dilation and another, in animals with renal insufficiency, characterised not only by marked cell edema and mitochondrial changes, but also by proximal tubule regenerative aspects without overt tubular necrosis. Interstitial edema and focal nephritis was prominent in both groups, a finding which minimises their role in the pathogenesis of renal failure in experimental leptospirosis. Vascular injury, affecting the vessels of the renal microcirculation chiefly at the cortico-medular junction, was observed in both groups. Its severity and extension ran parallel to the intensity of the tubular injury. This suggests a simultaneous action of a noxious agent liberated by the leptospires over both structures, tubular damage being accentuated by the local circulatory changes. PMID- 7131130 SO - J Pathol 1982 Oct;138(2):145-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83148575 AU - Riedemann S AU - Korts C AU - Zamora J TI - [Procedures for decontamination of Leptospira cultures] LA - Spa MH - Antibiotics/pharmacology MH - *Bacteriological Techniques MH - Decontamination MH - English Abstract MH - Filtration MH - Leptospira/drug effects/*growth & development RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 830407 DP - 1982 Oct IS - 0514-7166 TA - Zentralbl Veterinarmed [B] PG - 708-14 CY - GERMANY, WEST IP - 9 VI - 29 JC - Y72 EM - 8306 PMID- 6762020 CU - 91 TT - Procedimientos de decontaminacion de cultivos de leptospira. EA - A SO - Zentralbl Veterinarmed [B] 1982 Oct;29(9):708-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 83116509 AU - Tu V AU - Adler B AU - Faine S TI - The role of macrophages in the protection of mice against leptospirosis: in vitro and in vivo studies. LA - Eng MH - Animal MH - Comparative Study MH - Cyclophosphamide/pharmacology MH - Immunity, Natural MH - Immunosuppression MH - In Vitro MH - Leptospira interrogans/drug effects MH - Leptospirosis/*immunology MH - Macrophages/drug effects/*physiology MH - Mice MH - Mice, Inbred BALB C MH - Mycobacterium bovis/drug effects MH - Peritoneum/cytology MH - Phagocytosis/drug effects MH - Support, Non-U.S. Gov't RN - 50-18-0 (Cyclophosphamide) PT - JOURNAL ARTICLE DA - 830311 DP - 1982 Oct IS - 0031-3025 TA - Pathology PG - 463-8 SB - M CY - AUSTRALIA IP - 4 VI - 14 JC - OTA AA - Author EM - 8305 AB - Balb/c mice are naturally resistant to infection with Leptospira interrogans serovar copenhageni, but leptospires were not phagocytosed by mouse peritoneal macrophages in vitro without added specific antibody. Similar results were obtained irrespective of whether leptospires were viable or killed, virulent or avirulent, or whether macrophages were obtained from normal mice, immunized mice or mice previously infected with BCG. Suppression or stimulation of macrophage function in vivo did not affect the outcome of infection of immunosuppressed mice with leptospires; specific antibody was essential for protection from infection. PMID- 6760092 CU - 90 SO - Pathology 1982 Oct;14(4):463-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83037817 AU - Blackmore DK AU - Schollum LM TI - Risks of contracting leptospirosis on the dairy farm. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Comparative Study MH - *Dairying MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - New Zealand MH - Occupational Diseases/*epidemiology MH - Risk MH - Sex Factors MH - Sheep MH - Support, Non-U.S. Gov't MH - Swine MH - Time Factors PT - JOURNAL ARTICLE DA - 821218 DP - 1982 Sep 22 IS - 0028-8446 TA - N Z Med J PG - 649-52 SB - M CY - NEW ZEALAND IP - 716 VI - 95 JC - OBQ AA - Author EM - 8302 AB - The sera of 460 people associated with farming were examined for evidence of leptospiral agglutinins. Of these, 308 were dairy farm workers, 62 percent of whom were from the Waikato. Forty-four percent of dairy farm workers, 8 percent of sheep and beef farmers and 25 percent of pig farmers ware seropositive. Of the 137 seropositive dairy farm workers, 65 percent had titres to serovar hardjo and 53 percent to pomona. There were no significant differences between the serological prevalences of workers in different geographical regions. Analysis of factors significantly associated with seropositive workers included; being male, a previous history of medically confirmed leptospirosis in the worker, a clinical history of leptospirosis in the cattle, the size of the milking herd, the type of milking shed, and vaccination of the herd against leptospirosis. These findings indicate that the incidence of leptospirosis in dairy farm workers can only be effectively controlled by reducing the prevalence of infection in dairy cattle. PMID- 6957789 CU - 90 SO - N Z Med J 1982 Sep 22;95(716):649-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 83095955 AU - Ueno K AU - Yanagawa R AU - Kida H TI - Presence of Vi antigen in a virulent strain of leptospira interrogans serovar pomona and relation of Vi antigens of leptospiras to resistance to leptospiricidal activity mediated by antiserum plus complement. LA - Eng MH - Antigens, Bacterial/*immunology MH - Azaguanine/pharmacology MH - Complement/immunology MH - Immune Sera/immunology MH - Leptospira interrogans/*immunology/pathogenicity RN - 0 (Antigens, Bacterial) RN - 134-58-7 (Azaguanine) RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 830214 DP - 1982 Sep TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 557-65 SB - M CY - GERMANY, WEST IP - 4 VI - 252 JC - Y5N AA - Author EM - 8304 AB - Vi antigen was found in a virulent strain of Leptospira interrogans serovar pomona. The presence of Vi antigen was shown by the agglutinin- absorption and precipitin-absorption tests. Each strain of pomona and copenhageni which possessed Vi antigen and was resistant to the leptospiricidal activity mediated by the antiserum plus complement lost Vi antigen and became susceptible to the leptospiricidal activity when cultured in the presence of 8-azaguanine. The strains thus treated with 8-azaguanine recovered the resistance and Vi antigen when cultured in medium without 8-azaguanine. PMID- 7180239 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1982 Sep;252(4):557-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83171005 AU - Amato Neto V AU - de Avila CA AU - Kawarabayashi M TI - [Leptospira meningitis: cases reported in the city of Sao Paulo, during an epidemic outbreak of meningococcal disease] LA - Por MH - Adolescence MH - Adult MH - Brazil MH - Cerebrospinal Fluid/microbiology MH - Child MH - Child, Preschool MH - *Disease Outbreaks MH - English Abstract MH - Female MH - Hemagglutination Tests MH - Human MH - Leptospira/isolation & purification MH - *Leptospirosis/diagnosis MH - Male MH - Meningitis/*microbiology MH - Meningitis, Aseptic/*microbiology PT - JOURNAL ARTICLE DA - 830527 DP - 1982 Sep-Oct IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 322-5 CY - BRAZIL IP - 5 VI - 24 JC - S9D EM - 8307 RO - M:CNR PMID- 7167710 LR - 930720 CU - 90 TT - Meningite por Leptospira: casuistica derivada, na cidade de Sao Paulo, de surto epidemico de doenca meningococica. EA - A SO - Rev Inst Med Trop Sao Paulo 1982 Sep-Oct;24(5):322-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 83126329 AU - Slatter DH AU - Hawkins CD TI - Prevalence of leptospiral titres in normal horses. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Australia MH - Climate MH - Horses/*immunology MH - Leptospira interrogans/classification/*immunology MH - Serotyping/veterinary MH - Tropical Climate RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830311 DP - 1982 Sep IS - 0005-0423 TA - Aust Vet J PG - 84-6 SB - M CY - AUSTRALIA IP - 3 VI - 59 JC - 9IE AA - Author EM - 8305 AB - Serum samples were collected from 479 clinically normal horses from 11 different locations in Queensland. Using a microscopic agglutination test, 157 serums (33%) reacted to one or more serovars of Leptospira interrogans at a minimum serum dilution of 1/30. The prevalences of reactors among all horses to the serovars tested were pomona 30.5% icterohaemorrhagiae 23.9%, tarassovi 18.8%, hardjo 12.2%, canicola 8.6%, grippotyphosa 3.6%, and australis 2%. There was a significantly higher prevalence of reactors in tropical areas than in sub-tropical areas, but no difference in prevalence between coastal and non-coastal areas. PMID- 7159313 CU - 91 SO - Aust Vet J 1982 Sep;59(3):84-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83051685 AU - Pecchini F AU - Borghi M AU - Bodini U AU - Copercini B AU - Grutta d'Auria C AU - Romanini GL AU - Romano C TI - Acute renal failure from leptospirosis: new trends of treatment [letter] LA - Eng MH - Hemodialysis MH - Human MH - Kidney Failure, Acute/*therapy MH - Leptospirosis/*complications MH - Middle Age PT - LETTER DA - 830107 DP - 1982 Sep IS - 0301-0430 TA - Clin Nephrol PG - 164 SB - M CY - GERMANY, WEST IP - 3 VI - 18 JC - DEY EM - 8303 PMID- 7140030 CU - 91 SO - Clin Nephrol 1982 Sep;18(3):164 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83051068 AU - Kral L AU - Dite P AU - Vitek J TI - [Acute pancreatitis in leptospirosis] LA - Cze MH - Acute Disease MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*complications/diagnosis MH - Male MH - Pancreatitis/*complications/diagnosis PT - JOURNAL ARTICLE DA - 830119 DP - 1982 Sep IS - 0009-0565 TA - Cesk Gastroenterol Vyz PG - 333-8 CY - CZECHOSLOVAKIA IP - 6 VI - 36 JC - CTK EM - 8303 PMID- 7139740 TT - Akutni pankreatitis u leptospirozy. SO - Cesk Gastroenterol Vyz 1982 Sep;36(6):333-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83064925 AU - Robertson MH TI - Leptospirosis. LA - Eng MH - Antibiotics/therapeutic use MH - Gastrointestinal Hemorrhage/etiology/therapy MH - Human MH - Hygiene MH - Kidney Failure, Acute/etiology/therapy MH - Leptospirosis/complications/*diagnosis/therapy MH - Occupational Diseases/prevention & control RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 830119 DP - 1982 Sep IS - 0032-6518 TA - Practitioner PG - 1552-7 CY - ENGLAND IP - 1371 VI - 226 JC - PHQ EM - 8303 PMID- 6983063 CU - 91 SO - Practitioner 1982 Sep;226(1371):1552-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83077372 AU - Jeandel P AU - Raoult D AU - Bauduceau B AU - Rougier Y AU - Mailloux M AU - Auger C TI - [Epidemiological aspects and diagnosis of 60 cases of leptospiroses in French Polynesia] LA - Fre MH - Adult MH - Antibodies, Bacterial/analysis MH - Blood/microbiology MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Leptospira/immunology/isolation & purification MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*diagnosis/epidemiology/transmission MH - Male MH - Polynesia RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830225 DP - 1982 Aug-Oct IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 367-74 SB - M CY - FRANCE IP - 4 VI - 75 JC - C4G AA - Author EM - 8304 AB - 60 cases of leptospiroses were diagnosed in Polynesia by blood culture and immunological test. Fever and pains are prevailing signs. Among 3 patients, presence of leptospires is revealed on the 43th, 54th and 90th days. The following serogroups are found: Icterohaemorrhagiae 69.7%, Canicola 13%, Pomona 4%, Australis 2%. 85% of the patients come from Tahiti and 15% from "Sousle-Vent" Islands and Tuamotou. Walking bare foot on wet ground in areas where numerous rodents are found is a source of contamination. The procedure of blood cultures plays a prominent part. PMID- 7172357 CU - 91 TT - Aspects epidemiologiques et diagnostiques de 60 cas de leptospiroses observes en Polynesie Francaise. EA - A SO - Bull Soc Pathol Exot Filiales 1982 Aug-Oct;75(4):367-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 83074338 AU - Whyte PB AU - Ratcliff RM AU - Cargill C AU - Dobson KJ TI - Protection of pregnant swine by vaccination against Leptospira infection. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Bacterial Vaccines/*administration & dosage MH - Comparative Study MH - Female MH - Leptospira interrogans/*immunology MH - Pregnancy MH - Pregnancy Complications, Infectious/prevention & control/*veterinary MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/veterinary MH - Weil's Disease/prevention & control/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 830119 DP - 1982 Aug IS - 0005-0423 TA - Aust Vet J PG - 41-5 SB - M CY - AUSTRALIA IP - 2 VI - 59 JC - 9IE AA - Author EM - 8303 AB - The protection conferred on pregnant gilts by 2 commercially available leptospira interrogans serovars pomona and tarassovi bacterins was evaluated. Gilts vaccinated either 3, 6 or 12 months prior to natural challenge with L. interrogans serovar pomona had significantly lower abortion rates (2% vs 69%) and foetal mortality rates (14% vs 57%) than unvaccinated controls. One vaccine was significantly superior to the other and contained approximately twice the number of L. interrogans serovar pomona organisms per vaccine dose. Neither vaccine protected against renal colonisation but vaccination reduced urinary excretion of leptospires. Both vaccines reduced agglutinating antibody response to infection, as measured by the microscopic agglutination (MA) test. This may prevent the detection of a carrier animal by serology. Foetal pigs did not develop specific MA titres. Cultural methods were not reliable in making a diagnosis of foetal infection. Histopathology of foetal liver and kidneys helped in making a diagnosis of foetal infection. PMID- 7150130 CU - 91 SO - Aust Vet J 1982 Aug;59(2):41-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 83048045 AU - Lai KN AU - Aarons I AU - Woodroffe AJ AU - Clarkson AR TI - Renal lesions in leptospirosis. LA - Eng MH - Adult MH - Antigen-Antibody Complex/immunology MH - Human MH - Immunoglobulins/immunology MH - Kidney/*pathology MH - Kidney Diseases/etiology/immunology/*pathology MH - Kidney Glomerulus/immunology MH - Leptospirosis/immunology/*pathology MH - Male MH - Middle Age MH - Nephritis, Interstitial/etiology/immunology/pathology RN - 0 (Antigen-Antibody Complex) PT - JOURNAL ARTICLE DA - 821218 DP - 1982 Aug IS - 0004-8291 TA - Aust N Z J Med PG - 276-9 SB - M CY - AUSTRALIA IP - 4 VI - 12 JC - 9H9 AA - Author EM - 8302 AB - Renal function studies and kidney biopsies were performed in four patients presenting with renal insufficiency and acute Leptospira pomona infection. The renal lesion in all patients revealed acute interstitial nephritis. There was no evidence of immunologically mediated disease in three patients who were biopsied seven, eight and eight days respectively following the onset of symptoms. The fourth, in whom there was no evidence of prior renal disease, and whose biopsy was performed 16 days after symptoms began, showed glomerular Clq, and C3 immunofluorescence and mesangial, subepithelial and intramembranous dense deposits by electron microscopy. In addition, circulating immune complexes were demonstrated in this patient. These findings suggest that in this instance at least, the renal lesions of Leptospira pomona infections can be immunologically mediated. Because this may well be a transient phase, the timing of investigations could be crucial to its detection. PMID- 6958239 CU - 92 SO - Aust N Z J Med 1982 Aug;12(4):276-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 83010181 AU - Robinson AJ AU - Ramadass P AU - Lee A AU - Marshall RB TI - Differentiation of subtypes within Leptospira interrogans serovars Hardjo, Balcanica and Tarassovi, by bacterial restriction-endonuclease DNA analysis (BRENDA). LA - Eng MH - Base Sequence MH - DNA Restriction Enzymes MH - DNA, Bacterial/*analysis MH - Leptospira interrogans/analysis/*classification MH - Serotyping RN - EC 3.1.21 (DNA Restriction Enzymes) RN - EC 3.1.21.- (Deoxyribonuclease BamHI) RN - EC 3.1.21.- (Deoxyribonuclease EcoRI) RN - EC 3.1.21.- (Deoxyribonuclease HindIII) RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 821202 DP - 1982 Aug IS - 0022-2615 TA - J Med Microbiol PG - 331-8 SB - M CY - ENGLAND IP - 3 VI - 15 JC - J2N AA - Author EM - 8301 AB - Various strains of Leptospira interrogans were compared by bacterial restriction-endonuclease DNA analysis (BRENDA). Field strains of serovar hardjo isolated from domestic animals in New Zealand, Australia and Northern Ireland were indistinguishable from one another but differed strikingly from the hardjo reference strain Hardjoprajitno. Similarly, field isolates of balcanica and tarassovi differed from their serovar reference strains, probably owing to a difference in epidemiological niche. Subdivision of these serovars into distinct subtypes as defined by BRENDA is therefore useful and justified. In contrast, analysis of serovars pomona, ballum and copenhageni shows that field and reference strains were identical, or differed only by a single band. It is suggested that BRENDA will overcome many of the problems associated with serological methods of identifying serovars and allow more precise definition of epidemiological relationships between strains and their hosts. PMID- 6288951 CU - 93 SO - J Med Microbiol 1982 Aug;15(3):331-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83017799 AU - Hathaway SC AU - Little TW AU - Stevens AE TI - Isolation of Leptospira interrogans serovar muenchen from a sow with a history of abortion. LA - Eng MH - Abortion, Veterinary/*etiology MH - Agglutination Tests/veterinary MH - Animal MH - Female MH - Kidney/microbiology MH - Leptospira interrogans/classification/*isolation & purification MH - Pregnancy MH - Serotyping MH - Swine MH - Swine Diseases/*etiology MH - Weil's Disease/etiology/*veterinary PT - JOURNAL ARTICLE DA - 821202 DP - 1982 Jul 31 IS - 0042-4900 TA - Vet Rec PG - 100-2 SB - M CY - ENGLAND IP - 5 VI - 111 JC - XBS AA - Author EM - 8301 AB - The isolation of Leptospira interrogans serovar muenchen from a sow which aborted in the first third of pregnancy is described. Isolation was achieved only in media containing a rabbit serum additive and identification was determined by cross-agglutination absorption. A high degree of cross-reactivity was found with reference antisera of the Australis serogroup. Serovar muenchen has not previously been reported in animals and may be responsible for a proportion of the titres to antigens of the Australis serogroup that have recently been reported in pigs in England. PMID- 7123827 SO - Vet Rec 1982 Jul 31;111(5):100-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 82273277 AU - Blackmore DK AU - Schollum L TI - The occupational hazards of leptospirosis in the meat industry. LA - Eng MH - Animal MH - Cattle MH - Female MH - Human MH - Leptospirosis/*epidemiology/etiology MH - Male MH - *Meat-Packing Industry MH - New Zealand MH - Occupational Diseases/*epidemiology/etiology MH - Risk MH - Support, Non-U.S. Gov't MH - Swine PT - JOURNAL ARTICLE DA - 821029 DP - 1982 Jul 28 IS - 0028-8446 TA - N Z Med J PG - 494-7 SB - M CY - NEW ZEALAND IP - 712 VI - 95 JC - OBQ AA - Author EM - 8212 AB - The sera from 1215 meat inspectors and 1248 meat workers were examined for the presence of agglutinating titres of 1:24 or greater to the serovars of Leptospira interrogans known to be endemic in New Zealand. Although 10 percent of meat inspectors and 6.2 percent of meat workers were seropositive, only 9.5 percent of meat inspectors and 4.1 percent of meat workers had titres compatible with occupational exposure to domestic stock. The subgroup of meat workers with the highest prevalence of agglutinins (10.4 percent) were those working on the slaughter floor, and the inspection and processing of pigs were shown to be the most important risk factors. More than 50 percent of those with a history of medically confirmed leptospirosis in the past ten years still had detectable titres. Although the results of this survey demonstrate that leptospirosis is a definite occupational hazard in the meat industry, the risk is threefold less than for dairy farm workers and pig farmers. PMID- 6955684 CU - 90 SO - N Z Med J 1982 Jul 28;95(712):494-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83017794 AU - Hathaway SC AU - Little TW AU - Stevens AE TI - Isolation of Leptospira interrogans serovar hardjo from aborted bovine fetuses in England. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Fetus/*microbiology MH - Leptospira interrogans/*isolation & purification MH - Pregnancy MH - Weil's Disease/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 821202 DP - 1982 Jul 17 IS - 0042-4900 TA - Vet Rec PG - 58 SB - M CY - ENGLAND IP - 3 VI - 111 JC - XBS EM - 8301 PMID- 7123824 SO - Vet Rec 1982 Jul 17;111(3):58 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83095551 AU - Fischer J AU - Markus R AU - Baumgarten R AU - Fengler JD AU - Bartke D TI - [Leptospirosis--a case report] LA - Ger MH - Abattoirs MH - Adolescence MH - Case Report MH - Diagnosis, Differential MH - Germany, East MH - Human MH - Male MH - Occupational Diseases/*diagnosis MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 830214 DP - 1982 Jul 15 IS - 0044-2178 TA - Z Arztl Fortbild (Jena) PG - 641-4 SB - M CY - GERMANY, EAST IP - 14 VI - 76 JC - XS6 EM - 8304 PMID- 7180032 TT - Die Leptospirose--ein Fallbericht. SO - Z Arztl Fortbild (Jena) 1982 Jul 15;76(14):641-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83090691 AU - Peter G TI - Leptospirosis: a zoonosis of protean manifestations. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Child MH - Diagnosis, Differential MH - Dogs/microbiology MH - Female MH - Human MH - Leptospirosis/diagnosis/drug therapy/*epidemiology MH - Male MH - Penicillins/therapeutic use MH - Prognosis MH - Risk MH - Tetracycline/therapeutic use MH - United States MH - Zoonoses/*epidemiology RN - 0 (Penicillins) RN - 60-54-8 (Tetracycline) PT - JOURNAL ARTICLE DA - 830214 DP - 1982 Jul-Aug IS - 0277-9730 TA - Pediatr Infect Dis PG - 282-8 SB - M CY - UNITED STATES IP - 4 VI - 1 JC - PA4 EM - 8304 PMID- 7177918 CU - 92 SO - Pediatr Infect Dis 1982 Jul-Aug;1(4):282-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83074330 AU - Swart KS AU - Calvert K AU - Meney C TI - The prevalence of antibodies to serovars of Leptospira interrogans in horses. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Australia MH - Horse Diseases/epidemiology MH - Horses/*immunology MH - Leptospira interrogans/classification/*immunology MH - Serotyping MH - Weil's Disease/epidemiology/veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830119 DP - 1982 Jul IS - 0005-0423 TA - Aust Vet J PG - 25-7 SB - M CY - AUSTRALIA IP - 1 VI - 59 JC - 9IE EM - 8303 PMID- 7150126 CU - 91 SO - Aust Vet J 1982 Jul;59(1):25-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83066573 AU - Perraro F AU - Moro A AU - Aldorati M AU - Paniek M AU - Lestuzzi A AU - Marino B TI - [Leptospirosis: epidemiological and clinico-therapeutic observations] LA - Ita MH - Adult MH - Aged MH - Drug Therapy, Combination MH - English Abstract MH - Female MH - Hemodialysis MH - Human MH - Italy MH - Leptospirosis/diagnosis/*epidemiology/therapy MH - Male MH - Middle Age MH - Penicillins/administration & dosage MH - Peritoneal Dialysis MH - Weil's Disease/diagnosis/epidemiology/therapy RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 830119 DP - 1982 Jul IS - 0034-1193 TA - Recenti Prog Med PG - 18-32 CY - ITALY IP - 1 VI - 73 JC - R1T EM - 8303 PMID- 7146602 CU - 92 TT - Leptospirosi: osservazioni epidemiologiche e clinico-terapeutiche. EA - A SO - Recenti Prog Med 1982 Jul;73(1):18-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83043891 AU - Ono E AU - Naiki M AU - Yanagawa R TI - Production and characterization of monoclonal antibodies to lipopolysaccharide antigen of Leptospira interrogans serovar kremastos and canicola. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*classification/immunology MH - Antibodies, Monoclonal/*classification/immunology MH - Hybridomas MH - IgG/metabolism MH - IgM/metabolism MH - Leptospira interrogans/classification/*immunology MH - Mice MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Monoclonal) PT - JOURNAL ARTICLE DA - 821221 DP - 1982 Jul TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 414-24 SB - M CY - GERMANY, WEST IP - 3 VI - 252 JC - Y5N AA - Author EM - 8302 AB - Monoclonal antibodies to Leptospira interrogans were provided by cell fusions between a myeloma cell line, P3/X63-Ag8.653, and spleen cells of BALB/c mice immunized with two different leptospiral lipopolysaccharide antigens. One antigen was prepared from Leptospira interrogans serovar kremastos strain Kyoto and the other from serovar canicola strain Hond Utrecht IV. Eighteen hybridoma cell lines secreting monoclonal antibodies to the former organisms and five hybridoma cell lines secreting monoclonal antibodies to the latter organisms were established during 6 month cultivation. On the basis of their microscopic agglutination reactivities, 18 anti-kremastos Kyoto monoclonal antibodies were classified into 10 distinct groups, and 5 anti-canicola monoclonal antibodies into 3 distinct groups. PMID- 7136356 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1982 Jul;252(3):414-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83043890 AU - Adler B AU - Chappel RJ AU - Faine S TI - The sensitivities of different immunoassays for detecting leptospiral antigen. LA - Eng MH - Agglutination Tests MH - Antigens, Bacterial/*analysis MH - Comparative Study MH - Counterimmunoelectrophoresis MH - Enzyme-Linked Immunosorbent Assay MH - Leptospira interrogans/*immunology MH - Radioimmunoassay MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 821221 DP - 1982 Jul TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 405-13 SB - M CY - GERMANY, WEST IP - 3 VI - 252 JC - Y5N AA - Author EM - 8302 AB - The detection of leptospiral antigen in biological fluids is important for the diagnosis of leptospirosis in animals and man. However the sensitivity of dark field microscopy, the usual detection method, is often inadequate. A comparison was made between the sensitivities of several immunological techniques for detecting Leptospira interrogans serovar hardjo. By staphylococcal coagglutination 10(8) leptospires per ml could be detected and by countercurrent immunoelectrophoresis 10(7) per ml. The best sensitivity obtained by enzyme-linked immunosorbent assay was 10(5) leptospires per ml, and by radioimmunoassay 10(4) to 10(5) per ml. Radioimmunoassay offers the prospect of improved diagnosis of leptospirosis through the detection of leptospiral antigen. PMID- 7136355 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1982 Jul;252(3):405-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 82254822 AU - White FH AU - Sulzer KR AU - Engel RW TI - Isolations of Leptospira interrogans serovars hardjo, balcanica, and pomona from cattle at slaughter. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle/immunology/*microbiology MH - Female MH - Florida MH - Kidney/*microbiology MH - Leptospira interrogans/immunology/*isolation & purification MH - Male RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820910 DP - 1982 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1172-3 SB - M CY - UNITED STATES IP - 7 VI - 43 JC - 40C AA - Author EM - 8211 AB - Kidneys were cultured for leptospires and blood was collected for leptospiral serologic examination from 306 cattle slaughtered in Florida during June, July, and August 1980. Leptospires were found in 82(36%) of 226 otherwise bacterial-free cultures. Forty-five isolates were identified as Leptospira interrogans serovar hardjo, 3 as serovar balcanica, and 3 as serovar pomona. Leptospiral antibodies were found in 218 (71%) of the cattle. Serum titers to hardjo were found in 162 cattle (53%) and to pomona in 28 (9%). Low titers to tarassovi were found in 14 cattle (4.5%). PMID- 7103197 CU - 91 SO - Am J Vet Res 1982 Jul;43(7):1172-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 82254300 AU - Edwards CN AU - Nicholson GD AU - Everard CO TI - Thrombocytopenia in leptospirosis. LA - Eng MH - Adult MH - Female MH - Human MH - Kidney Failure, Acute/etiology MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Platelet Count MH - Retrospective Studies MH - Thrombocytopenia/*etiology PT - JOURNAL ARTICLE DA - 820917 DP - 1982 Jul IS - 0002-9637 TA - Am J Trop Med Hyg PG - 827-9 SB - A SB - M CY - UNITED STATES IP - 4 VI - 31 JC - 3ZQ AA - Author EM - 8211 AB - In a retrospective study undertaken to document the frequency of thrombocytopenia in cases of leptospirosis, 18 of 32 patients (56.3%) had a platelet count of 100 x 10(3)/mm3 or less. Renal failure occurred in 72.2% of thrombocytopenic patients and in 21.4% of patients with normal platelet counts. The association of thrombocytopenia and renal failure was significant (P less than 0.02). The common occurrence of thrombocytopenia and its association with acute renal failure in patients with leptospirosis has not previously been reported. PMID- 7102918 CU - 84 SO - Am J Trop Med Hyg 1982 Jul;31(4):827-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83081862 AU - Edelweiss EL AU - Mailloux M TI - The curve of immunoglobulins in human leptospirosis. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/biosynthesis MH - Human MH - IgA/metabolism MH - IgG/metabolism MH - IgM/metabolism MH - Immunoglobulins/*metabolism MH - Leptospira/immunology MH - Leptospirosis/*immunology MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830214 DP - 1982 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 51-6 SB - M CY - TAIWAN IP - 1 VI - 9 JC - GTK EM - 8304 PMID- 7174234 CU - 91 SO - Int J Zoonoses 1982 Jun;9(1):51-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83081861 AU - Farrington NP AU - Sulzer KR TI - Canine leptospirosis in Puerto Rico. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antigens, Bacterial/analysis MH - Dog Diseases/*microbiology MH - Dogs MH - Female MH - Leptospira/classification MH - Leptospirosis/microbiology/*veterinary MH - Male MH - Puerto Rico MH - Serotyping/veterinary MH - Zoonoses RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 830214 DP - 1982 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 45-50 SB - M CY - TAIWAN IP - 1 VI - 9 JC - GTK AA - Author EM - 8304 AB - Among 116 stray dogs in Puerto Rico surveyed for leptospiral agglutinins, 73 (62.9%) has significant titers to one or more leptospiral serotypes. The most common serogroup identified serologically was icterohaemorrhagiae accounting for 53 (72.6%) of the infections. Although the infection rates were comparable for male and female dogs the older were found to be more frequently infected. The significance of the canine in the epidemiology of leptospirosis in Puerto Rico is probably of paramount importance due to the extensive direct and indirect contact dogs have with rats and the human population. PMID- 7174233 CU - 91 SO - Int J Zoonoses 1982 Jun;9(1):45-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83043197 AU - Segree W AU - Fitz-Henly M AU - Rawlins J AU - Bowen-Wright C TI - Leptospirosis: a review of the Jamaican experience compared with other Caribbean territories. LA - Eng MH - Adult MH - Animal MH - Cattle MH - Child MH - Child, Preschool MH - Comparative Study MH - Dogs MH - Female MH - Human MH - Jamaica MH - Leptospirosis/*epidemiology/transmission MH - Male MH - Mice MH - Rats MH - West Indies PT - JOURNAL ARTICLE DA - 821216 DP - 1982 Jun IS - 0043-3144 TA - West Indian Med J PG - 54-60 CY - JAMAICA IP - 2 VI - 31 JC - XN4 EM - 8302 PMID- 7135931 CU - 88 SO - West Indian Med J 1982 Jun;31(2):54-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 83018002 AU - Jezyna C AU - Holowaty A AU - Korczynska A TI - [Effect of penicillin on the behavior of the agglutination reaction in the treatment of field fever] LA - Pol MH - Adolescence MH - Adult MH - Aged MH - Agglutinins/*analysis MH - Child MH - English Abstract MH - Female MH - Fever/drug therapy MH - Human MH - Leptospirosis/*drug therapy MH - Male MH - Middle Age MH - Penicillins/*pharmacology/therapeutic use RN - 0 (Agglutinins) RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 821203 DP - 1982 Jun 1 IS - 0043-5147 TA - Wiad Lek PG - 405-10 CY - POLAND IP - 6 VI - 35 JC - XOA EM - 8301 PMID- 7123929 CU - 92 TT - Wplyw penicyliny na zachowanie sie odczynu aglutynacyjnego w przebiegu leczenia goraczki blotnej. EA - A SO - Wiad Lek 1982 Jun 1;35(6):405-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 82264718 AU - Lindenbaum I TI - Leptospirosis in Israel: epidemiological features and laboratory findings in 13 human cases due to Leptospira ballum. LA - Eng MH - Adult MH - Aged MH - Agglutination MH - Antibodies, Bacterial/analysis MH - Female MH - Human MH - IgG/analysis MH - IgM/analysis MH - Israel MH - Leptospirosis/diagnosis/*epidemiology/immunology MH - Male MH - Middle Age RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 821012 DP - 1982 Jun IS - 0021-2180 TA - Isr J Med Sci PG - 659-65 SB - M CY - ISRAEL IP - 6 VI - 18 JC - GY0 AA - Author EM - 8212 AB - Thirteen sporadic cases of human leptospirosis due to Leptospira ballum were laboratory confirmed during a period of 11 yr. In four cases the diagnosis was proved retrospectively. All but three were residents of the Sharon plain region, living 10 to 15 km apart. All were engaged in some form of agriculture, especially in irrigated fields or groves, or in chicken farming. It was suspected that wet soil contaminated with the urine of rodents, carriers of L. ballum, was the main source of infection. Two types of immunological response were observed: 1) high microscopic agglutination (MA) titers with L. ballum serovar only (nine cases); and 2) considerable coagglutination titers with heterologous serovars as well (four cases). The serological follow-up of these cases for several years revealed that in some, a relatively high MA titer (1:200 to 1:400) against L. ballum serovars persisted for 4 to 9 yr. Sera from 10 patients were tested for IgM and IgG anti-bodies by the MA test. In eight cases the IgM responded to a higher titer and persisted for many years, regardless of whether or not any IgG agglutinins were detected. The importance of blood cultures is emphasized and the possibility of misinterpretation of MA results is discussed. PMID- 7107200 CU - 91 SO - Isr J Med Sci 1982 Jun;18(6):659-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [63 medline neighbors] UI - 82229087 AU - Tatlock H TI - The causative organism in Fort Bragg fever [letter] LA - Eng MH - Human MH - Legionella MH - Leptospira MH - Leptospirosis/*microbiology PT - LETTER DA - 820807 DP - 1982 Jun IS - 0003-4819 TA - Ann Intern Med PG - 789-90 SB - A SB - M CY - UNITED STATES IP - 6 Pt 1 VI - 96 JC - 5A6 EM - 8210 PMID- 7091947 CU - 91 SO - Ann Intern Med 1982 Jun;96(6 Pt 1):789-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 82254787 AU - Barnes MA AU - Wright RE AU - Bodine AB AU - Alberty CF TI - Frequency of bluetongue and bovine parvovirus infection in cattle in South Carolina dairy herds. LA - Eng MH - Abortion, Septic/epidemiology/immunology/veterinary MH - Abortion, Veterinary/epidemiology/immunology MH - Animal MH - Bluetongue/*epidemiology MH - Bluetongue Virus/immunology MH - Cattle MH - Cattle Diseases/*epidemiology/immunology MH - Ceratopogonidae MH - Female MH - Infertility, Female/epidemiology/etiology/veterinary MH - Insect Vectors MH - Leptospirosis/veterinary MH - Parvoviridae/immunology MH - Pregnancy MH - Reproduction MH - Sheep MH - South Carolina MH - Support, U.S. Gov't, Non-P.H.S. MH - Virus Diseases/complications/epidemiology/immunology/*veterinary PT - JOURNAL ARTICLE DA - 820910 DP - 1982 Jun IS - 0002-9645 TA - Am J Vet Res PG - 1078-80 SB - M CY - UNITED STATES IP - 6 VI - 43 JC - 40C AA - Author EM - 8211 AB - A survey of South Carolina diary cattle in 12 commercial herds was conducted, using serologic testing to determine the frequency and impact on reproduction of bluetongue (BT) and bovine parvovirus (BFV) infections. Results of the study of serum antibodies titers and dairy cattle health records indicated that the majority of the cattle surveyed was adequately protected against the major reproductive tract diseases through vaccination programs. The frequency of reproductive dysfunction was common in vaccinated herds, however. Six of the 12 herds in the survey had cattle which were BT serotest reactors, although total numbers of these reactor cattle were relatively small. Further, reproductive performance of reactor cows indicated that BT was of little consequence and was not associated with reproductive problems. All herds contained BPV serotest reactors and the latter comprised 59.7% of the total number of cows surveyed. The BPV seroreactor cows were commonly associated with the group of reproductive problem cows which experienced higher rates of embryonic mortality and more services per conception than did nonreactor cattle. The results of the survey emphasize the need for continued investigation and efforts to control BT, and especially BPV infection, in dairy cattle. RO - M:CNR PMID- 6285770 LR - 931119 CU - 93 SO - Am J Vet Res 1982 Jun;43(6):1078-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 83034520 AU - Kawaoka Y AU - Naiki M AU - Yanagawa R TI - Isolation of the antigen-active components from leptospiral serovar- specific lipopolysaccharide antigen by mild acid hydrolysis. LA - Eng MH - Antigens, Bacterial/analysis/*isolation & purification MH - Chemistry MH - Comparative Study MH - Epitopes/analysis/*isolation & purification MH - Formates MH - Hydrolysis MH - Leptospira interrogans/*immunology MH - Lipopolysaccharides/analysis/*isolation & purification MH - Molecular Weight MH - Sulfuric Acids MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) RN - 0 (Formates) RN - 0 (Lipopolysaccharides) RN - 0 (Sulfuric Acids) RN - 64-18-6 (formic acid) PT - JOURNAL ARTICLE DA - 821218 DP - 1982 Jun IS - 0021-5295 TA - Nippon Juigaku Zasshi PG - 473-8 CY - JAPAN IP - 3 VI - 44 JC - KRJ EM - 8302 PMID- 6182330 CU - 95 SO - Nippon Juigaku Zasshi 1982 Jun;44(3):473-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82220657 AU - Bosio G AU - Bramato C AU - Salassa B AU - Andreoni G TI - [Epidemiologic and clinical studies of 6 cases of leptospirosis from the province of Turin] LA - Ita MH - Adult MH - Ampicillin/therapeutic use MH - English Abstract MH - Human MH - Italy MH - Leptospirosis/drug therapy/*epidemiology MH - Male MH - Middle Age MH - Penicillin G/therapeutic use RN - 61-33-6 (Penicillin G) RN - 69-53-4 (Ampicillin) PT - JOURNAL ARTICLE DA - 820807 DP - 1982 May 26 IS - 0026-4806 TA - Minerva Med PG - 1563-6 SB - M CY - ITALY IP - 22 VI - 73 JC - N6M AA - Author EM - 8210 AB - Six cases of leptospirosis from the outer suburbs of province of Turin are presented. Some epidemiological aspects are considered, and reference is made to the need for early diagnosis, along with prompt antibiotic management to ensure successful resolution. Mention is also made of the need for careful control of renal function, since its impairment is the most serious complication associated with leptospirosis. PMID- 7088384 CU - 88 TT - Osservazioni epidemiologiche e cliniche su 6 casi di leptospirosi provenienti dalla provincia torinese. EA - A SO - Minerva Med 1982 May 26;73(22):1563-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 82246172 AU - Schollum LM AU - Blackmore DK TI - Leptospirosis of pig farmers: the results of a serological survey. LA - Eng MH - Animal MH - *Animal Husbandry MH - Health Surveys MH - Human MH - Leptospirosis/diagnosis/*epidemiology/transmission/veterinary MH - New Zealand MH - Occupational Diseases/diagnosis/*epidemiology MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/transmission PT - JOURNAL ARTICLE DA - 820910 DP - 1982 May 12 IS - 0028-8446 TA - N Z Med J PG - 299-301 SB - M CY - NEW ZEALAND IP - 707 VI - 95 JC - OBQ AA - Author EM - 8211 AB - Serum samples were examined from 70 people working or resident on 41 pig farms within a 50 km radius of Palmerston North. Of the 65 people with occupational pig contact, 20 (31 percent) had microscopic agglutination titres of 1:24 or greater to one or more serovars of Leptospira interrogans, the majority of which were to pomona, the pid adapted serovar. There were significant positive associations between those people with a titre and those with a history of previous diagnosis of leptospirosis by a medical practitioner and the number of breeding sows and fattening pigs on the property. Pig farmers are at similar risk to contracting leptospirosis as dairy farmers, but the major serovars involved are different, and the total population at risk is less. Further evidence is provided that titres to leptospiral agglutinins can persist in humans for longer than ten years. RO - M:CNR PMID- 6954386 LR - 850820 CU - 88 SO - N Z Med J 1982 May 12;95(707):299-301 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 82228930 AU - Bey RF AU - Johnson RC TI - Immunogenicity and humoral and cell-mediated immune responses to leptospiral whole cell, outer envelope, and protoplasmic cylinder vaccines in hamsters and dogs. LA - Eng MH - Animal MH - *Antibody Formation MH - Bacterial Vaccines/*immunology MH - Comparative Study MH - Cross Reactions MH - Dog Diseases/*immunology/prevention & control MH - Dogs MH - Hamsters MH - IgG/analysis MH - IgM/analysis MH - Immunity, Cellular MH - Leptospira canicola/immunology MH - Leptospira interrogans/growth & development/*immunology MH - Leptospirosis/immunology/prevention & control/*veterinary MH - Lymphocyte Transformation MH - Male MH - Mesocricetus MH - Rodent Diseases/*immunology/prevention & control MH - Support, U.S. Gov't, P.H.S. RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE ID - AI-06589/AI/NIAID DA - 820814 DP - 1982 May IS - 0002-9645 TA - Am J Vet Res PG - 835-40 SB - M CY - UNITED STATES IP - 5 VI - 43 JC - 40C AA - Author EM - 8210 AB - The immunogenicity of 2 leptospiral cell structural components, the outer envelope (OE) and protoplasmic cylinder (PC), as well as the leptospire whole cell (WC), was compared in hamsters and dogs. The 50% protective dose for hamsters against death (PD50D) and kidney infection (PD50k) was evaluated for Leptospira interrogans serovars canicola, icterohaemorrhagiae, pomona, and grippotyphosa. All 3 immunogens had similar PD50D values. However, the PD50K values for OE and WC vaccines ranged from 0.05 to 0.80 micrograms (dry weight), whereas the PC vaccines ranged from 7.0 to 14.0 micrograms. Cellular and humoral responses of dogs to serovar canicola WC, OE, and PC vaccines were monitored for 21 weeks. Little difference was observed among the canine humoral responses to the different preparations. Protoplasmic cylinder vaccines sensitized the greater population of lymphoid cells followed by OE and WC. Cross-reactivity was greater in the blastogenic response of lymphoid cell populations than in the humoral response. PMID- 7201285 CU - 96 SO - Am J Vet Res 1982 May;43(5):835-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 83059603 AU - Adler B AU - Faine S TI - Evidence that leptospiral lipopolysaccharide is not an important protective antigen. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Cyclophosphamide/pharmacology MH - Leptospira interrogans/*immunology MH - Lipopolysaccharides/*immunology MH - Mice MH - Mice, Inbred BALB C/immunology MH - Mice, Inbred CBA/immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Lipopolysaccharides) RN - 50-18-0 (Cyclophosphamide) PT - JOURNAL ARTICLE DA - 830107 DP - 1982 May IS - 0022-2615 TA - J Med Microbiol PG - 259-62 SB - M CY - ENGLAND IP - 2 VI - 15 JC - J2N AA - Author EM - 8303 AB - CBA/N mice, which could not produce antibodies against lipopolysaccharide (LPS) from either Escherichia coli or Leptospira interrogans serovar pomona, produced levels of agglutinating antibodies against leptospires similar to those produced by immunologically normal CBA mice. CBA/N mice were thus resistant to acute leptospiral infection and CBA/N immune serum passively protected immunosuppressed mice from infection. The results suggest that antibodies against LPS are not important in protection against experimental leptospiral infection in mice. PMID- 7143431 CU - 91 SO - J Med Microbiol 1982 May;15(2):259-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 83026664 AU - Pan ZA TI - [Animal reservoir of leptospirosis in Hainan Island] LA - Chi MH - Animal MH - Cattle MH - China MH - *Disease Reservoirs MH - Dogs MH - English Abstract MH - Female MH - Leptospira/*isolation & purification MH - Male MH - Muridae/microbiology MH - Rats MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 821216 DP - 1982 May TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 160-2 CY - CHINA IP - 3 VI - 16 JC - D74 EM - 8302 PMID- 7128325 EA - A SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1982 May;16(3):160-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 83018469 TI - [Detection of bacteria and fungi in blood samples. German Society for Hygiene and Microbiology. Commission for guidelines for microbiological diagnosis] LA - Ger MH - Bacteria/growth & development MH - Blood/*microbiology MH - Brucella/growth & development MH - Culture Media MH - Fungi/*growth & development MH - Human MH - L Forms/growth & development MH - Leptospira/growth & development MH - Microbial Sensitivity Tests MH - Mycoplasma/growth & development MH - Mycoses/*diagnosis MH - Septicemia/*diagnosis MH - Ureaplasma/growth & development MH - Yeasts/growth & development RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 821202 DP - 1982 May TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 1-8 SB - M CY - GERMANY, WEST IP - 1 VI - 252 JC - Y5N EM - 8301 PMID- 7124156 CU - 91 NI - A TT - Nachweis von Bakterien und Pilzen aus Blutproben. Deutsche Gesellschaft fur Hygiene und Mikrobiologie. Kommission zur Erarbeitung von Richtlinien fur Mikrobiologische Diagnostik. SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1982 May;252(1):1-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 82249173 AU - Hathaway SC AU - Little TW AU - Stevens AE TI - Failure to demonstrate the maintenance of leptospires by house mice (Mus musculus) in the south east of England. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Comparative Study MH - England MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification MH - Mice/immunology/*microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820924 DP - 1982 May IS - 0034-5288 TA - Res Vet Sci PG - 387-8 SB - M CY - ENGLAND IP - 3 VI - 32 JC - R7D AA - Author EM - 8211 AB - A total of 272 house mice (Mus musculus) were trapped in farm buildings at four widely separated locations of south east England and examined for serological and bacteriological evidence of leptospiral infection. Only two low titres to autumnalis antigen (1:20 and 1:40) were recorded and all mice were bacteriologically negative. The absence of leptospiral infection in the house mouse in south east England is an interesting ecological finding, as this species is a maintenance host for ballum in many countries and also a common carrier of several other serovars. The source of ballum infections in domestic stock in England remains unknown. PMID- 7100658 CU - 91 SO - Res Vet Sci 1982 May;32(3):387-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82239747 AU - Arimitsu Y AU - Kobayashi S AU - Akama K AU - Matuhasi T TI - Development of a simple serological method for diagnosing leptospirosis: a microcapsule agglutination test. LA - Eng MH - Agglutination Tests/*methods MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial MH - Complement Fixation Tests MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis MH - Plastics MH - Support, Non-U.S. Gov't MH - Weil's Disease/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Plastics) PT - JOURNAL ARTICLE DA - 820910 DP - 1982 May IS - 0095-1137 TA - J Clin Microbiol PG - 835-41 SB - M CY - UNITED STATES IP - 5 VI - 15 JC - HSH AA - Author EM - 8211 AB - A passive microcapsule agglutination test for the diagnosis of leptospirosis was developed by utilizing chemically stable microcapsules instead of sheep erythrocytes. In the test, sonically disrupted antigens of leptospira were sensitized to microcapsules treated with glutaraldehyde. Compared with the microscopic agglutination test, the passive microcapsule agglutination test showed a relatively genus-specific tendency and a 4- to 32-fold-higher sensitivity. The sensitized microcapsule antigens were stable for at least 1 year. The microcapsules coupled with mixed antigens can be used as a serodiagnostic screening test for diseases caused by various types of leptospira. The test, which is very simple and reproducible and requiring no specific training, can be employed easily as a routine test in diagnostic laboratories. PMID- 7096558 CU - 92 SO - J Clin Microbiol 1982 May;15(5):835-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 82228946 AU - Navarro CE AU - Kociba GJ TI - Hemostatic changes in dogs with experimental Leptospira interrogans serovar icterohaemorrhagiae infection. LA - Eng MH - Animal MH - Dog Diseases/*blood MH - Dogs MH - *Hemostasis MH - Leptospira interrogans MH - Leptospirosis/blood/*veterinary MH - Platelet Count MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 820814 DP - 1982 May IS - 0002-9645 TA - Am J Vet Res PG - 904-6 SB - M CY - UNITED STATES IP - 5 VI - 43 JC - 40C EM - 8210 PMID- 7091860 SO - Am J Vet Res 1982 May;43(5):904-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 82228929 AU - Bey RF AU - Johnson RC TI - Leptospiral vaccines in dogs: immunogenicity of whole cell and outer envelope vaccines prepared in protein-free medium. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - *Antibody Formation MH - Bacterial Vaccines/*immunology MH - Culture Media MH - Dog Diseases/microbiology/*prevention & control MH - Dogs MH - Kidney/microbiology MH - Leptospira interrogans/growth & development/*immunology/isolation & purification MH - Leptospirosis/microbiology/prevention & control/*veterinary MH - Support, U.S. Gov't, P.H.S. RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (Culture Media) PT - JOURNAL ARTICLE ID - AI-06589/AI/NIAID DA - 820814 DP - 1982 May IS - 0002-9645 TA - Am J Vet Res PG - 831-4 SB - M CY - UNITED STATES IP - 5 VI - 43 JC - 40C AA - Author EM - 8210 AB - The immunogenicity of leptospires cultivated in modified bovine albumin- polysorbate 80 medium and those cultivated in protein-free medium were quantitatively evaluated in the dog. Vaccine preparations, whole cell or outer envelope, prevented leptospiremia; however, kidney culture data revealed that 1 of 4 dogs vaccinated with 0.1 to 1 mg of whole cell prepared from leptospires cultivated in the modified bovine albumin-polysorbate 80 medium was positive for Leptospira, whereas dogs vaccinated with whole cells prepared in protein-free medium were not. Dogs vaccinated with greater than or equal to 0.5 mg of outer envelope were refractory to infection after challenge exposure. PMID- 7091847 CU - 96 SO - Am J Vet Res 1982 May;43(5):831-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 82228918 AU - Thiermann AB TI - Experimental leptospiral infections in pregnant cattle with organisms of the Hebdomadis serogroup. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*diagnosis/pathology MH - Comparative Study MH - Female MH - Kidney/pathology MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/diagnosis/pathology/*veterinary MH - Milk/microbiology MH - Pregnancy MH - Pregnancy Complications, Infectious/diagnosis/pathology/*veterinary MH - Urine/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820814 DP - 1982 May IS - 0002-9645 TA - Am J Vet Res PG - 780-4 SB - M CY - UNITED STATES IP - 5 VI - 43 JC - 40C AA - Author EM - 8210 AB - The clinical and pathologic implications of leptospirosis caused by organisms of the Hebdomadis serogroup were tested on 8 pregnant cows. The animals were inoculated after their 5th month of pregnancy, 2 with serovar szwajizak and 6 with serovar hardjo. During the acute phase of the infection, the cows had mild signs of clinical illness; however, mastitis was observed in all cows that calved. One cow aborted, and 2 delivered premature and weak calves. By bacteriologic cultural examination, a short leptospiremic phase was observed. Leptospires were isolated from milk of 5 cows during early phases of mastitis; these isolations were obtained only when using solid media. Leptospiruria was determined by culture and direct examination. Only hardjo-inoculated cows had detectable urinary shedding which was observed to extend past 450 days in 1 cow. Leptospires were isolated from tissues of all cows and from 2 calves at necropsy. Interstitial nephritis was observed in all cows necropsied. Histologically, leptospires were demonstrated in silver-stained sections of kidney, liver, and lung of most calves. Leptospires were also observed in sections of kidney of all cows necropsied and in the cotyledons, placenta, and liver of some. Agglutinating titers were detected in the serum of cows as early as 4 days after inoculation and reached maximum titer (81,920) after 20 days. Significant serum titers persisted for the duration of the experiment only in hardjo-inoculated cows. At birth, all calves had no detectable agglutinins, but seroconverted within 24 hours; the serum titers were similar to those found in the dam's milk. PMID- 7091839 CU - 91 SO - Am J Vet Res 1982 May;43(5):780-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [57 medline neighbors] UI - 83095519 AU - Gear JH TI - The hemorrhagic fevers of Southern Africa with special reference to studies in the South African Institute for Medical Research. LA - Eng MH - Adult MH - Africa, Southern MH - Animal MH - Bacterial Infections/*epidemiology MH - Case Report MH - Female MH - Hemorrhage/*etiology MH - Hemorrhagic Fevers, Viral/*epidemiology MH - Herpes Simplex/diagnosis MH - Human MH - Leptospirosis/diagnosis MH - Malaria/diagnosis MH - Male MH - Marburg Virus Disease/diagnosis MH - Meningococcal Infections/epidemiology MH - Plague/epidemiology MH - Pneumonia, Lobar/epidemiology MH - Relapsing Fever/epidemiology MH - Rickettsia Infections/epidemiology MH - Rubella/diagnosis MH - Septicemia/complications MH - Trypanosomiasis, African/diagnosis MH - Yellow Fever/epidemiology PT - JOURNAL ARTICLE DA - 830225 DP - 1982 May-Aug IS - 0044-0086 TA - Yale J Biol Med PG - 207-12 SB - M CY - UNITED STATES IP - 3-4 VI - 55 JC - XR7 AA - Author EM - 8304 AB - In this review of studies on the hemorrhagic fevers of Southern Africa carried out in the South African Institute for Medical Research, attention has been called to occurrence of meningococcal septicemia in recruits to the mining industry and South African Army, to cases of staphylococcal and streptococcal septicemia with hemorrhagic manifestations, and to the occurrence of plague which, in its septicemic form, may cause a hemorrhagic state. "Onyalai," a bleeding disease in tropical Africa, often fatal, was related to profound thrombocytopenia possibly following administration of toxic witch doctor medicine. Spirochetal diseases, and rickettsial diseases in their severe forms, are often manifested with hemorrhagic complications. Of enterovirus infections, Coxsackie B viruses occasionally caused severe hepatitis associated with bleeding, especially in newborn babies. Cases of hemorrhagic fever presenting in February-March, 1975 are described. The first outbreak was due to Marburg virus disease and the second, which included seven fatal cases, was caused by Rift Valley fever virus. In recent cases of hemorrhagic fever a variety of infective organisms have been incriminated including bacterial infections, rickettsial diseases, and virus diseases, including Herpesvirus hominis; in one patient, the hemorrhagic state was related to rubella. A boy who died in a hemorrhagic state was found to have Congo fever; another patient who died of severe bleeding from the lungs was infected with Leptospira canicola, and two patients who developed a hemorrhagic state after a safari trip in Northern Botswana were infected with Trypanosoma rhodesiense. An illness manifested by high fever and melena developed in a young man after a visit to Zimbabwe; the patient was found to have both malaria and Marburg virus disease. PMID- 6897472 CU - 88 SO - Yale J Biol Med 1982 May-Aug;55(3-4):207-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 83012405 AU - Arsen'eva LP TI - [Natural-focus zoonoses in Afghanistan (a review of the literature)] LA - Rus MH - Afghanistan MH - Animal MH - *Disease Reservoirs MH - English Abstract MH - Human MH - Leishmaniasis/epidemiology MH - Leishmaniasis, Visceral/epidemiology MH - Leptospirosis/epidemiology MH - Plague/epidemiology MH - Rickettsia Infections/epidemiology MH - Spirochaetales Infections/epidemiology MH - Tularemia/epidemiology MH - Virus Diseases/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE PT - REVIEW DA - 821202 DP - 1982 May-Jun IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 54-9 CY - USSR IP - 3 VI - 51 JC - M72 EM - 8301 RF - 40 PMID- 6750342 CU - 90 TT - Prirodno-ochagovye zoonozy v Afganistane (obzor literatury). EA - A SO - Med Parazitol (Mosk) 1982 May-Jun;51(3):54-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 83285211 AU - Shang DQ TI - [A brief account on the study at an international course on zoonoses at Moscow, 1981] LA - Chi MH - Animal MH - Brucellosis/epidemiology/prevention & control MH - Human MH - Leptospirosis/epidemiology/prevention & control MH - Rabies/epidemiology/prevention & control MH - Rabies Vaccine/therapeutic use MH - *Zoonoses RN - 0 (Rabies Vaccine) PT - JOURNAL ARTICLE DA - 831008 DP - 1982 Apr TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 124-8 CY - CHINA IP - 2 VI - 3 JC - CQG EM - 8312 PMID- 7185445 CU - 91 SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1982 Apr;3(2):124-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83073862 AU - Nicolescu M AU - Andreescu N TI - A new preparation of Patoc antigen for the serological diagnosis by the CFT of human leptospirosis. LA - Eng MH - Agglutination Tests MH - *Antigens MH - *Complement Fixation Tests MH - Human MH - Leptospirosis/*diagnosis RN - 0 (Antigens) PT - JOURNAL ARTICLE DA - 830107 DP - 1982 Apr-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 137-9 CY - ROMANIA IP - 2 VI - 41 JC - 8EM EM - 8303 PMID- 7149959 CU - 91 SO - Arch Roum Pathol Exp Microbiol 1982 Apr-Jun;41(2):137-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 83073861 AU - Nicolescu M AU - Andreescu N TI - Human Icterohaemorrhagiae leptospirosis after bathing in rivers (1977- 1981). LA - Eng MH - Bathing Beaches MH - Human MH - Leptospira interrogans/*isolation & purification MH - Romania MH - *Water Microbiology MH - Weil's Disease/epidemiology/*etiology PT - JOURNAL ARTICLE DA - 830107 DP - 1982 Apr-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 133-6 CY - ROMANIA IP - 2 VI - 41 JC - 8EM EM - 8303 PMID- 7149958 CU - 88 SO - Arch Roum Pathol Exp Microbiol 1982 Apr-Jun;41(2):133-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 83022069 AU - Whyte PB AU - Ratcliff RM TI - The possible role of the common field mouse (Mus musculus) in the epidemiology of leptospirosis in pigs [letter] LA - Eng MH - Animal MH - Leptospira interrogans/*pathogenicity MH - Mice/*microbiology MH - Rodent Diseases/*transmission MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*transmission MH - Weil's Disease/transmission/*veterinary PT - LETTER DA - 821202 DP - 1982 Apr IS - 0005-0423 TA - Aust Vet J PG - 169 SB - M CY - AUSTRALIA IP - 4 VI - 58 JC - 9IE EM - 8301 PMID- 7126066 CU - 91 SO - Aust Vet J 1982 Apr;58(4):169 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83009000 AU - Banfi E AU - Cinco M AU - Bellini M AU - Soranzo MR TI - The role of antibodies and serum complement in the interaction between macrophages and leptospires. LA - Eng MH - Animal MH - Antibodies, Bacterial/*immunology MH - Bacteriolysis MH - Complement/*immunology MH - Guinea Pigs MH - IgG/*immunology MH - Leptospira/*immunology/ultrastructure MH - Macrophages/*immunology MH - Microscopy, Electron MH - Opsonins MH - Phagocytosis MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Opsonins) RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 821202 DP - 1982 Apr IS - 0022-1287 TA - J Gen Microbiol PG - 813-6 SB - M CY - ENGLAND VI - 128 (Pt 4) JC - I87 AA - Author EM - 8301 AB - Guinea-pig macrophages exerted bactericidal activity against both a virulent and a saprophytic strain of leptospira in the presence of the homologous IgG. Serum complement alone rendered the saprophytic strain susceptible to phagocytosis by the same macrophages. PMID- 7119745 CU - 92 SO - J Gen Microbiol 1982 Apr;128 (Pt 4):813-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 82201922 AU - Stoianova NA AU - Popova EM AU - Sergeiko LM AU - Potachev AF TI - [Nature of the antibodies in persons inoculated with a leptospirosis vaccine] LA - Rus MH - Adult MH - Antibodies, Bacterial/*analysis/classification MH - Antibody Specificity MH - Bacterial Vaccines/*administration & dosage MH - English Abstract MH - Human MH - IgG/analysis MH - IgM/analysis MH - Immunization, Secondary MH - Leptospira/*immunology MH - Time Factors RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 820719 DP - 1982 Apr IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 93-5 SB - M CY - USSR IP - 4 JC - Y9O AA - Author EM - 8209 AB - The results obtained in the study of the intensity and character of immunity in persons immunized with commercial leptospirosis vaccine are presented. These results indicate that antibody formation occurs only in 12.5% of the vaccinees; antibodies are not formed to all Leptospira strains contained in the vaccine, and in 6 months all antibodies completely disappear. In persons immunized with a single vaccine dose the agglutinating activity of blood sera was linked only with IgM. In persons subjected to multiple immunizations for a number of years IgG could also be detected. Cases of leptospirosis among vaccinees have been registered. PMID- 7080768 CU - 91 TT - Priroda antitel u liudei, privitykh leptospiroznoi vaktsinoi. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1982 Apr;(4):93-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 83285206 AU - Wen RZ TI - [Detection of blood leptospirae by indirect fluorescent antibody staining technic] LA - Chi MH - Antibodies, Bacterial/immunology MH - *Fluorescent Antibody Technique MH - Human MH - Leptospira/immunology/*isolation & purification MH - Staining RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 831008 DP - 1982 Apr TA - Chung Hua Liu Hsing Ping Hsueh Tsa Chih PG - 106-8 CY - CHINA IP - 2 VI - 3 JC - CQG EM - 8312 PMID- 6192928 CU - 95 SO - Chung Hua Liu Hsing Ping Hsueh Tsa Chih 1982 Apr;3(2):106-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 82174235 AU - Guivarch G AU - Le Gall JR AU - Regnier B AU - Jardin F TI - [Shock during leptospirosis icterohaemorrhagica. Four cases (author's transl)] LA - Fre MH - Adult MH - Aged MH - Case Report MH - English Abstract MH - Heart Ventricle/physiopathology MH - Hemodynamics MH - Human MH - Male MH - Middle Age MH - Myocarditis/complications MH - Oxygen/blood MH - Pulmonary Wedge Pressure MH - Shock/*etiology/physiopathology MH - Shock, Cardiogenic/etiology MH - Shock, Septic/etiology MH - Vascular Resistance MH - Weil's Disease/*complications RN - 7782-44-7 (Oxygen) PT - JOURNAL ARTICLE DA - 820614 DP - 1982 Mar 6 IS - 0301-1518 TA - Nouv Presse Med PG - 837-9 SB - M CY - FRANCE IP - 11 VI - 11 JC - O5Q AA - Author EM - 8208 AB - Four patients with leptospirosis icterohaemorrhagica (LH) were admitted to an intensive care unit in a state of shock. Haemodynamic studies showed that the shock was due to three different mechanisms which were often associated or successive in the same patient: (1) septic shock with fall of systemic vascular resistance (SVR) and no widening of arteriovenous oxygen difference (AVDO2); (2) cardiogenic shock, probably due in part to specific myocarditis, with reduced left ventricular work and normal or high pulmonary wedge pressure; and (3) hypovolaemic shock with the increased SVR and widened AVDO2. These data suggest that haemodynamic studies are required in patients with LIH associated with shock in order to determine its mechanism and provide guidelines for its treatment. PMID- 7070975 TT - Etats de choc au cours des leptospiroses ictero-hemorragiques. Quatre observations. EA - A SO - Nouv Presse Med 1982 Mar 6;11(11):837-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 82188441 AU - Melish ME AU - Hicks RV AU - Reddy V TI - Kawasaki syndrome: an update. LA - Eng MH - Adult MH - Aspirin/administration & dosage MH - Child MH - Child, Preschool MH - Coronary Vessels/radiography MH - Diagnosis, Differential MH - Follow-Up Studies MH - Hawaii MH - Heart Aneurysm/etiology MH - Heart Diseases/etiology MH - Human MH - Japan/ethnology MH - Leptospirosis/diagnosis MH - *Lymphatic Diseases/complications/diagnosis MH - Male MH - Measles/diagnosis MH - *Mucocutaneous Lymph Node Syndrome/complications/diagnosis MH - Prognosis RN - 50-78-2 (Aspirin) PT - JOURNAL ARTICLE DA - 820719 DP - 1982 Mar IS - 8755-4542 TA - Hosp Pract (Hosp Ed) PG - 99-106 CY - UNITED STATES IP - 3 VI - 17 JC - HPH EM - 8209 RO - M:CNR PMID- 7200458 LR - 910724 CU - 90 SO - Hosp Pract (Hosp Ed) 1982 Mar;17(3):99-106 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 83013914 AU - Herr S AU - Riley AE AU - Neser JA AU - Roux D AU - De Lange JF TI - Leptospira interrogans serovar pomona associated with abortion in cattle: isolation methods and laboratory animal histopathology. LA - Eng MH - Abortion, Veterinary/blood/*etiology/urine MH - Animal MH - Cattle MH - Female MH - Guinea Pigs MH - Hamsters MH - Kidney/pathology MH - Leptospira interrogans/*isolation & purification/pathogenicity MH - Liver/pathology MH - Male MH - Methods MH - Pregnancy MH - Weil's Disease/complications/immunology/*veterinary PT - JOURNAL ARTICLE DA - 821202 DP - 1982 Mar IS - 0030-2465 TA - Onderstepoort J Vet Res PG - 57-62 SB - M CY - SOUTH AFRICA IP - 1 VI - 49 JC - OI6 AA - Author EM - 8301 AB - Leptospira interrogans serovar pomona was successfully isolated from cattle urine in the western Transvaal after an abortion storm had occurred. Direct inoculation of EMJH medium proved the most successful method. The selective agent, 5-fluorouracil, was most effective in controlling contamination when used at the 0,4 mg/ml level. The strain isolated was pathogenic in hamsters, but specific lesions and the leptospirae were seen only where overwhelming infection occurred. PMID- 7122066 CU - 90 SO - Onderstepoort J Vet Res 1982 Mar;49(1):57-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 82283725 AU - Allen JD AU - Meney CL AU - Wilks CR TI - Evaluation of a hardjo-pomona vaccine to prevent leptospiruria in cattle exposed to a natural challenge with Leptospira interrogans serovar hardjo. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacterial Vaccines/*immunology MH - Bacteriuria/prevention & control/*veterinary MH - Cattle MH - Cattle Diseases/*prevention & control MH - Female MH - Leptospira interrogans/*immunology MH - Leptospirosis/prevention & control/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 821012 DP - 1982 Mar IS - 0005-0423 TA - Aust Vet J PG - 93-6 SB - M CY - AUSTRALIA IP - 3 VI - 58 JC - 9IE AA - Author EM - 8212 AB - The efficacy of a vaccine against Leptospira interrogans serovar pomona and Leptospira interrogans serovar hardjo was evaluated in a group of dairy heifers that were serologically negative at the time of vaccination and later subjected to natural challenge with L. interogans serovar hardjo. Thirty-nine heifers were vaccinated twice, at a one- month interval, with a commercially prepared bivalent vaccine, while 43 unvaccinated heifers were used as controls. After vaccination, microscopic agglutination (MA) titres of serums to L. interrogans serovar hardjo ranged from 32 to 512, and those to L. interrogans serovar pomona ranged from 32 to 2048. Titres resulting from vaccination were short-lived and after the first vaccination the serums of 95% of vaccinated heifers did not react in the MA test by 24 weeks. The first indication of infection in the heifers was noted at week 6, and by week 16, elevated MA titres (greater than or equal to 128) to L. interrogans serovar hardjo had occurred in 62% of unvaccinated heifers and had increased to 85% by week 24. At week 18, 18% of the vaccinated heifers and 56% of the unvaccinated heifers had leptospiruria (p less than 0.01); after 22 weeks, 13% of the vaccinated heifers and 58% of the unvaccinated heifers showed evidence of leptospiruria (p less than 0.01). PMID- 7115235 CU - 91 SO - Aust Vet J 1982 Mar;58(3):93-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 82157176 AU - Shenberg E AU - Gerichter CB AU - Lindenbaum I TI - Leptospirosis in man, Israel, 1970-1979. LA - Eng MH - Agricultural Workers' Diseases/*epidemiology/transmission MH - Animal MH - Cattle MH - Dogs MH - Human MH - Israel MH - Leptospira/*classification MH - Leptospirosis/*epidemiology/transmission MH - Rats MH - Seasons MH - Serotyping MH - Swine MH - Zoonoses PT - JOURNAL ARTICLE DA - 820521 DP - 1982 Mar IS - 0002-9262 TA - Am J Epidemiol PG - 352-8 SB - M CY - UNITED STATES IP - 3 VI - 115 JC - 3H3 AA - Author EM - 8207 AB - In 1970-1979, the incidence of human leptospirosis in Israel was 0.7 per 100,000 population. The majority of the cases (62%) occurred in northeastern Israel (Upper Galilee). Prior to 1973 the main infecting serotypes were grippotyphosa (41%) and Hebdomadis szwajizak (31%). Following the first outbreak of Hebdomadis hardjo infection in 1973, a change occurred in the epidemiologic pattern of human leptospirosis, with hardjo becoming the most common serotype (59%). Hardjo infection outbreaks were sporadic and localized to dairy farms. The peak of incidence was during the summer months, June-September. All the patients with hardjo were dairy workers. The illness was relatively mild and mostly unicteric. Cattle seemed to be the principal source of hardjo infection for man. PMID- 7064970 CU - 88 SO - Am J Epidemiol 1982 Mar;115(3):352-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 82154163 AU - Cheng MK TI - A review of cerebrovascular surgery in the People's Republic of China. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Arteriovenous Malformations/surgery MH - Arteritis/complications MH - Cerebral Aneurysm/surgery MH - Cerebral Hemorrhage/complications/mortality/surgery MH - Cerebral Ischemia/surgery MH - Cerebral Ischemia, Transient/surgery MH - Cerebrovascular Disorders/mortality/*surgery MH - Child MH - Child, Preschool MH - China MH - Female MH - Human MH - Hypertension/complications MH - Infant MH - Leptospirosis/complications MH - Male MH - Middle Age MH - Moyamoya Disease/etiology/surgery MH - Syndrome PT - JOURNAL ARTICLE DA - 820527 DP - 1982 Mar-Apr IS - 0039-2499 TA - Stroke PG - 249-55 SB - M CY - UNITED STATES IP - 2 VI - 13 JC - V2J AA - Author EM - 8207 AB - Cerebrovascular disease (CBVD) is very common in the People's Republic of China (PRC). In 8 of 12 large cities in the PRC, CBVD ranked first in frequency as a cause of death. The ratio fo aneurysms to arteriovenous malformations (AVMs) was 0.84-2:1, much lower than in the United States (6.5:1). Hypertensive intracerebral hemorrhage (HIH) is the commonest cause of mortality in patients with CBVD; patients with ischemic stroke have been submitted to the extracranial-intracranial (EC-IC) arterial anastomosis since 1976. Moyamoya syndrome is not uncommon in the PRC; leptospiral arteritis was one of the major causes in the series that have been reported. PMID- 7064197 CU - 90 SO - Stroke 1982 Mar-Apr;13(2):249-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82261146 AU - Ouyang YM TI - [Outbreak of leptospirosis due to migration of field rodents (author's transl)] LA - Chi MH - Animal MH - China MH - Disease Outbreaks/*epidemiology MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology/etiology MH - Microtinae/*microbiology MH - Water Microbiology PT - JOURNAL ARTICLE DA - 821029 DP - 1982 Mar TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 96-7 CY - CHINA IP - 2 VI - 16 JC - D74 EM - 8212 PMID- 7049623 CU - 90 EA - A SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1982 Mar;16(2):96-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 82201873 AU - Litvin VIu AU - Golubev MV TI - [Analysis of the forrmation and dynamics of the "outside the body" portion of a population of the causative agent in a natural focus of leptospirosis] LA - Rus MH - Animal MH - Bacteriuria/microbiology MH - Comparative Study MH - *Disease Reservoirs MH - English Abstract MH - Leptospira/*isolation & purification MH - Leptospirosis/*microbiology MH - Microtinae/microbiology MH - Soil Microbiology MH - Time Factors MH - USSR PT - JOURNAL ARTICLE DA - 820708 DP - 1982 Mar IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 32-5 SB - M CY - USSR IP - 3 JC - Y9O AA - Author EM - 8209 AB - Field experiments with the use of radioisotope models have shown that urine containing leptospirae is regularly excreted in the same "infected spots" of the territory under study. For this reason, it is an increase in the frequency of Leptospira excretion in each "infected spot", rather than an increase in the number of such spots, which occurs in the course of the epizootic. To detect the "infected spots" on the experimental ground with the use of radioisotope models, the registration of such spots for 5-7 days is sufficient. The excretion of urine by animals in the "infected spots" has been shown to decrease the acidity of the soil, thus creating conditions favorable for the survival of leptospirae in the soil. PMID- 7043974 CU - 90 TT - K analizu formirovaniia i dinamiki "vneorganizmennoi" chasti populiatsii vozbuditelia v prirodnom ochage leptospiroza. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1982 Mar;(3):32-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 82200503 AU - Diallo AA AU - Dennis SM TI - Bacteriological survey of leptospirosis in Zaria, Nigeria. LA - Eng MH - Animal MH - Cattle/immunology/microbiology MH - Cattle Diseases/microbiology/transmission MH - *Disease Reservoirs MH - Disease Vectors MH - Gerbillinae/microbiology MH - Hedgehogs/microbiology MH - Kidney/microbiology MH - Leptospira interrogans/immunology/*isolation & purification MH - Leptospirosis/immunology/microbiology/*transmission MH - Mice/microbiology MH - Microtinae/microbiology MH - Muridae/microbiology MH - Nigeria MH - Rodent Diseases/microbiology/transmission MH - Rodentia/*microbiology MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 820708 DP - 1982 Mar IS - 0041-3232 TA - Trop Geogr Med PG - 29-34 SB - M CY - NETHERLANDS IP - 1 VI - 34 JC - WGJ AA - Author EM - 8209 AB - A total of 252 rodents were trapped in the environs of Ahmadu Bello University, Zaria, over a two-year period, of which 221 were brown field rats (Arvicanthus niloticus). Only these were found positive (4.5%). Titers were detected against Leptospira interrogans, serovars australis, icterohaemorrhagiae, tarassovi and hardjo. All positive sera except one reacted against a single serovar. Eight isolates were obtained from field rats: five were serovar australis, one ballum and two unidentified. Five isolates were recovered from 74 bovine kidneys examined: one was serovar pyrogenes and four unidentified. One unidentified isolate failed to react with any of the 16 screening leptospira antisera and another was tentatively considered to be serovar ballum. Two isolates, one ballum and one unidentified, were recovered from the Kubani stream waters. No leptospira was isolated from piggery sewage effluents collected at Kano and Kaduna. It is suggested that serovar ballum be included in any screening battery for leptospirosis in man and animals in Nigeria. PMID- 7043824 CU - 90 SO - Trop Geogr Med 1982 Mar;34(1):29-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [81 medline neighbors] UI - 82177621 AU - Ellis WA AU - Neill SD AU - O'Brien JJ AU - Cassells JA AU - Hanna J TI - Bovine leptospirosis: microbiological and serological findings in normal fetuses removed from the uteri after slaughter. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Cattle MH - Cattle Diseases/*epidemiology/microbiology MH - Fallopian Tubes/microbiology MH - Female MH - Fetus/*microbiology MH - Gestational Age MH - Leptospira interrogans/immunology MH - Pregnancy MH - Pregnancy Complications, Infectious/epidemiology/microbiology/*veterinary MH - Weil's Disease/epidemiology/microbiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820621 DP - 1982 Feb 27 IS - 0042-4900 TA - Vet Rec PG - 192-4 SB - M CY - ENGLAND IP - 9 VI - 110 JC - XBS AA - Author EM - 8208 AB - Leptospires were demonstrated by a combination of the direct fluorescent antibody technique and culture in six (4.6 per cent) of 130 fetuses from apparently normal uteri collected at an abattoir. Fetal ages ranged from the fifth to the seventh months. In addition, leptospires were isolated from the oviducts of two uteri whose fetuses were not infected. All the strains isolated were similar antigenically to serovar hardjo. Leptospiral antibodies were not detected in any of the fetuses. PMID- 7072119 CU - 91 SO - Vet Rec 1982 Feb 27;110(9):192-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82177618 AU - Ellis WA AU - O'Brien JJ AU - Neill SD AU - Hanna J TI - Bovine leptospirosis: serological findings in aborting cows. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*diagnosis MH - Complement Fixation Tests/veterinary MH - Female MH - Fetus/immunology MH - Leptospirosis/diagnosis/*veterinary MH - Pregnancy RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820624 DP - 1982 Feb 20 IS - 0042-4900 TA - Vet Rec PG - 178-80 SB - M CY - ENGLAND IP - 8 VI - 110 JC - XBS AA - Author EM - 8208 AB - The antibody titres of 149 cows aborting leptospire infected fetuses and 156 cows aborting fetuses not apparently infected with leptospires were determined by the microscopic agglutination (MA) test. There were differences in the distribution patterns of MA titres between the two groups of cows but these differences would only be of very limited value in the diagnosis of leptospiral abortion. Although 81.2 per cent of aborting cows which had a titre of 1:1000 or greater had leptospire infected fetuses, they represented 46.3 per cent of cows aborting leptospire infected fetuses. Among cows which aborted infected fetuses, 22.8 per cent had no detectable antibodies. The complement fixation and plate agglutination tests were of less value than the MA test. PMID- 7072116 CU - 91 SO - Vet Rec 1982 Feb 20;110(8):178-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 82141927 AU - Cole JR Jr AU - Sangster LT AU - Sulzer CR AU - Pursell AR AU - Ellinghausen HC TI - Infections with Encephalitozoon cuniculi and Leptospira interrogans, serovars grippotyphosa and ballum, in a kennel of foxhounds. LA - Eng MH - Animal MH - Case Report MH - Dog Diseases/*microbiology/pathology MH - Dogs MH - Encephalitozoon cuniculi MH - Leptospira interrogans/isolation & purification MH - Protozoan Infections/microbiology/pathology/*veterinary MH - Weil's Disease/microbiology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 820512 DP - 1982 Feb 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 435-7 SB - M CY - UNITED STATES IP - 4 VI - 180 JC - HAV AA - Author EM - 8207 AB - Leptospira interrogans serovars grippotyphosa and ballum were isolated from kidney and urine of an American Foxhound pup. The pup was from a litter of 12, all of which were unthrifty. Titers for serovar grippotyphosa in pups from the litter ranged from 200 to 6,400 and 23 of 36 adult dogs in the kennel had titers to that serovar. None of the sera was tested for antibodies to serovar ballum. Leptospires were not isolated from or observed in 2 littermates and 1 penmate, but gram- positive organisms morphologically compatible with Encephalitozoon cuniculi were detected in their brains and kidneys. PMID- 6800994 CU - 91 SO - J Am Vet Med Assoc 1982 Feb 15;180(4):435-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82154662 AU - Ellis WA AU - O'Brien JJ AU - Neill SD AU - Ferguson HW AU - Hanna J TI - Bovine leptospirosis: microbiological and serological findings in aborted fetuses. LA - Eng MH - Abortion, Veterinary/*diagnosis/microbiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*diagnosis/microbiology MH - Female MH - Fetal Diseases/diagnosis/microbiology/*veterinary MH - Fluorescent Antibody Technique/veterinary MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/microbiology/*veterinary MH - Pregnancy MH - Rabbits MH - Serodiagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820521 DP - 1982 Feb 13 IS - 0042-4900 TA - Vet Rec PG - 147-50 SB - M CY - ENGLAND IP - 7 VI - 110 JC - XBS AA - Author EM - 8207 AB - Leptospiral infection was diagnosed in 41.6 per cent of 245 randomly selected aborted bovine fetuses and 68.9 per cent of 103 aborted fetuses from farms with abortion problems. Diagnosis was based on combined leptospiral isolates from fetal kidney and eye, and fetal serology and immunofluorescence. Fifty-six of the 58 strains of leptospira isolated belonged to the Hebdomadis serogroup and were similar to serovar hardjo while one of the remaining two strains belonged to the Icterohaemorrhagiae serogroup and the other to the Canicola serogroup. These findings indicate that serovar hardjo infection is a major factor in the aetiology of bovine abortion and that it is possible to isolate this organism from fetal kidney by the careful application of dilution culture technique. PMID- 7039082 CU - 91 SO - Vet Rec 1982 Feb 13;110(7):147-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [98 medline neighbors] UI - 82154664 AU - English AW TI - Serological survey of wild fallow deer (Dama dama) in New South Wales, Australia. LA - Eng MH - Animal MH - Animals/*immunology MH - Animals, Wild/*immunology MH - Antibodies, Bacterial/*immunology MH - Antibodies, Viral/*immunology MH - Australia MH - Brucella abortus/immunology MH - Deer/*immunology MH - Female MH - Leptospira/immunology MH - Male MH - Viruses/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 820521 DP - 1982 Feb 13 IS - 0042-4900 TA - Vet Rec PG - 153-4 SB - M CY - ENGLAND IP - 7 VI - 110 JC - XBS EM - 8207 PMID- 6801845 CU - 91 SO - Vet Rec 1982 Feb 13;110(7):153-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [72 medline neighbors] UI - 82221958 AU - Gibson PJ AU - Ahmed SA AU - Coghlan JD TI - Leptospiral infection due to serotype castellonis of the ballum serogroup. A case report. LA - Eng MH - Adult MH - Animal MH - Case Report MH - Female MH - Gerbillinae MH - Hamsters MH - Human MH - Leptospirosis/*microbiology/transmission MH - Occupational Diseases/*microbiology MH - Rodent Diseases/transmission PT - JOURNAL ARTICLE DA - 820814 DP - 1982 Feb IS - 0032-6518 TA - Practitioner PG - 337-41 CY - ENGLAND IP - 1364 VI - 226 JC - PHQ EM - 8210 PMID- 7088832 SO - Practitioner 1982 Feb;226(1364):337-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 82199108 AU - Hadjoudj H AU - El Allaf D AU - Siquet J AU - Despas JM AU - Marcelle R AU - Van Cauwenberge H TI - [Leptospirosis] LA - Fre MH - Adult MH - Antibodies, Bacterial/analysis MH - Case Report MH - Human MH - Leptospirosis/*diagnosis/drug therapy MH - Male MH - Penicillins/therapeutic use MH - Weil's Disease/diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 820719 DP - 1982 Feb 1 IS - 0035-3663 TA - Rev Med Liege PG - 77-81 CY - BELGIUM IP - 3 VI - 37 JC - SM9 EM - 8209 PMID- 7079647 CU - 92 TT - La leptospirose. SO - Rev Med Liege 1982 Feb 1;37(3):77-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 82166749 AU - Lindenbaum I AU - Eylan E TI - Leptospirosis in Rattus norvegicus and Rattus rattus in Israel. LA - Eng MH - Agglutination Tests MH - Animal MH - Female MH - Israel MH - Kidney/microbiology MH - Leptospira/classification MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Male MH - Muridae/*microbiology MH - Rats/*microbiology MH - Rodent Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 820624 DP - 1982 Feb IS - 0021-2180 TA - Isr J Med Sci PG - 271-5 SB - M CY - ISRAEL IP - 2 VI - 18 JC - GY0 AA - Author EM - 8208 AB - Leptospires were isolated from 21.2% of Rattus norvegicus (the brown rat) and 9.9% of Rattus rattus trapped in a survey of urban and rural areas in Israel. Microagglutination antibodies were found in sera of 9.4 and 8.1% of these rats, respectively. The 191 strains isolated belonged to six serogroups: Leptospira icterohaemorrhagiae (169), L. bataviae (3), L. semeranga (1), L andamana (1) and L. ballum (1) from R. norvegicus and L. ballum (13) and L. hebdomadis (3) from R. rattus. No significant differences were found between the infection rate of mature male and female brown rats, but all six strains isolated from young animals were obtained from male rats. Two factors influence the rat of Leptospira infection among urban brown rats: the age of the animals and the area in which they are trapped. Adult brown rats trapped in a newly infected area showed a considerably higher level of contamination (61.8%) than those trapped in areas where the infection had persisted for many years (22.8%). Young rats showed a low degree of contamination in both the old foci (5.7%) and the new foci (2.2%). New and highly infected areas were found during this survey in Tel Aviv (Carmel market) and its neighboring cities of Holon, Ramat Gan and Givatayim. PMID- 7068359 CU - 88 SO - Isr J Med Sci 1982 Feb;18(2):271-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 82162010 AU - Polak S AU - Brozman M AU - Jakubovsky J AU - Bakoss P TI - [Morphological study of kidneys of mice with experimental leptospirosis (author's transl)] LA - Slo MH - Animal MH - English Abstract MH - Kidney/parasitology/*ultrastructure MH - Leptospira/ultrastructure MH - Leptospirosis/*pathology/parasitology MH - Mice PT - JOURNAL ARTICLE DA - 820614 DP - 1982 Feb IS - 0006-9248 TA - Bratisl Lek Listy PG - 146-58 CY - CZECHOSLOVAKIA IP - 2 VI - 77 JC - B5N EM - 8208 PMID- 7066713 TT - Morfologicke studium obliciek mysi s experimentalnou leptospirozou. EA - A SO - Bratisl Lek Listy 1982 Feb;77(2):146-58 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82155088 AU - Fedorov EI AU - Trubetskaia IA AU - Naglov VA AU - Kachanova MK TI - [Group leptospirosis infection in stock breeders] LA - Rus MH - Agricultural Workers' Diseases/*epidemiology/transmission MH - Animal MH - Disease Reservoirs MH - Disease Vectors MH - Human MH - Leptospirosis/*epidemiology/transmission MH - Ukraine PT - JOURNAL ARTICLE DA - 820527 DP - 1982 Feb IS - 0049-6804 TA - Vrach Delo PG - 114-6 CY - USSR IP - 2 JC - XLS EM - 8207 PMID- 7064439 CU - 88 TT - Gruppovoe zabolevanie zhivotnovodov leptospirozom. SO - Vrach Delo 1982 Feb;(2):114-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 82122019 AU - Patamasucon P AU - Schaad UB AU - Nelson JD TI - Melioidosis. LA - Eng MH - Animal MH - Antibiotics/therapeutic use MH - Bacteriological Techniques MH - Cardiovascular Diseases/etiology MH - Case Report MH - Central Nervous System Diseases/etiology MH - Child, Preschool MH - Diagnosis, Differential MH - Female MH - Human MH - Leptospirosis/diagnosis MH - Malaria/diagnosis MH - Melioidosis/complications/*diagnosis/drug therapy/microbiology MH - Pseudomonas/isolation & purification MH - Septicemia/diagnosis MH - Tuberculosis, Pulmonary/diagnosis MH - Typhoid/diagnosis RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 820422 DP - 1982 Feb IS - 0022-3476 TA - J Pediatr PG - 175-82 SB - A SB - M CY - UNITED STATES IP - 2 VI - 100 JC - JLZ EM - 8206 PMID- 7035636 CU - 91 SO - J Pediatr 1982 Feb;100(2):175-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 84019137 AU - Hathaway SC AU - Little TW AU - Stevens AE TI - Serological survey of leptospiral antibodies in sheep from England and Wales. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - England MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Sheep MH - Sheep Diseases/*immunology MH - Wales RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 831123 DP - 1982 Jan 30 IS - 0042-4900 TA - Vet Rec PG - 99-101 SB - M CY - ENGLAND IP - 5 VI - 110 JC - XBS AA - Author EM - 8401 AB - A total of 3722 sera was obtained from 188 flocks widely distributed throughout England and Wales; three sera were randomly selected from each flock and tested in the microscopic agglutination test for leptospiral antibodies. Infection with leptospires of the Hebdomadis serogroup was found to the widespread and it is probable that the infecting serovar is hardjo. The prevalence of hardjo titres in the random survey was 6.4 per cent and within-herd prevalences ranged up to 94.4 per cent. Titres to autumnalis antigen were found in 7.3 per cent of sera and evidence is presented that suggests a proportion of these titres are cross-reactions with agglutinins stimulated by infection with leptospires from other serogroups. Titres to bratislava antigen (Australis serogroup) were found in 3.4 per cent of sera. Within-herd prevalences of autumnalis and bratislava titres did not range above 16.7 per cent and 26.3 per cent respectively. PMID- 7186697 CU - 91 SO - Vet Rec 1982 Jan 30;110(5):99-101 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82149311 AU - Cursons RT AU - Pyke PA AU - Penniket J TI - The serological diagnosis of leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Formation MH - Brucellosis/diagnosis MH - Comparative Study MH - Diagnosis, Differential MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - IgG/analysis/immunology MH - IgM/analysis/immunology MH - Influenza/diagnosis MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/blood/*diagnosis/immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820521 DP - 1982 Jan 27 IS - 0028-8446 TA - N Z Med J PG - 36-7 SB - M CY - NEW ZEALAND IP - 700 VI - 95 JC - OBQ EM - 8207 PMID- 6950318 CU - 91 SO - N Z Med J 1982 Jan 27;95(700):36-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 82141898 AU - Krakowka S AU - Olsen RG AU - Axthelm MK AU - Rice J AU - Winters K TI - Canine parvovirus infection potentiates canine distemper encephalitis attributable to modified live-virus vaccine. LA - Eng MH - Animal MH - Distemper Virus, Canine/immunology MH - Dog Diseases/*etiology/pathology/prevention & control MH - Dogs MH - Encephalitis/etiology/pathology/*veterinary MH - Parvoviridae MH - Support, U.S. Gov't, P.H.S. MH - Viral Vaccines/adverse effects MH - Virus Diseases/complications/pathology/prevention & control/*veterinary RN - 0 (Viral Vaccines) PT - JOURNAL ARTICLE ID - 2 RO1-A-10922 DA - 820521 DP - 1982 Jan 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 137-9 SB - M CY - UNITED STATES IP - 2 VI - 180 JC - HAV AA - Author EM - 8207 AB - Twelve gnotobiotic dogs from 2 litters were allotted to 3 groups. Group A dogs received a modified-live polyvalent (canine distemper, adenovirus type 2, and parainfluenza virus and Leptospira -canicola- icterohemorrhagiae bacterin) vaccine 3 days prior to oral inoculation with canine parvovirus (CPV). Group B dogs received CPV alone. Group C dogs received 1 dose of vaccine only. In none of the 9 CPV-inoculated dogs did clinical signs of CPV infection develop, although high serum antibody titers for CPV developed in all of them. However, in 2 of the 5 CPV-inoculated vaccinates, canine distemper virus encephalomyelitis subsequently developed. The results suggested that CPV exerts an immunomodulating effect on canine immune responses and may be responsible for vaccination failures in dogs. PMID- 7061309 CU - 92 SO - J Am Vet Med Assoc 1982 Jan 15;180(2):137-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 82147285 AU - San Segundo D AU - Landinez R AU - Bustamante J AU - de Alvaro F AU - Perez Diaz V AU - Suliman N AU - Briso Montiano JM AU - Palencia A TI - [Leptospirosis caused by L. grippotyphosa accompanied by acute renal failure (author's transl)] LA - Spa MH - Adult MH - Case Report MH - Human MH - Jaundice/*etiology MH - Kidney Failure, Acute/*etiology MH - Leptospira/isolation & purification MH - Leptospirosis/*complications/microbiology MH - Male PT - JOURNAL ARTICLE DA - 820512 DP - 1982 Jan 10 IS - 0025-7753 TA - Med Clin (Barc) PG - 28-31 CY - SPAIN IP - 1 VI - 78 JC - LTQ EM - 8207 PMID- 7062800 TT - Leptospirosis gripotifosa y fracaso renal agudo. SO - Med Clin (Barc) 1982 Jan 10;78(1):28-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 84058829 AU - Miragliotta G AU - Barone G AU - Ricci G AU - Dimonte D AU - Marcuccio C AU - Fumarola D TI - In vitro effect of Leptospira icterohaemorrhagiae on human mononuclear leukocytes: comparison of virulent with non virulent strain. LA - Eng MH - Blood Coagulation Factors/biosynthesis MH - Human MH - Leptospira interrogans/*pathogenicity MH - Monocytes/*microbiology MH - Support, Non-U.S. Gov't RN - 0 (Blood Coagulation Factors) PT - JOURNAL ARTICLE DA - 840107 DP - 1982 Jan-Jun IS - 0390-5462 TA - G Batteriol Virol Immunol PG - 3-8 SB - M CY - ITALY IP - 1-6 VI - 75 JC - FAF AA - Author EM - 8403 AB - The in vitro effect of a virulent and a non virulent strain of Leptospira interrogans serotype icterohaemorrhagiae on human peripheral mononuclear cells was investigated. After addition of bacteria to citrated whole blood the production of mononuclear cell procoagulant activity (tissue factor) was observed. Indeed mononuclear cells isolated from whole blood-bacteria mixtures after prolonged incubation shortened the recalcification time of normal plasma. The virulent strain induced a significantly higher procoagulant activity than non virulent and this effect was dependent on the number of bacteria. The production of tissue factor, a potent trigger of blood clotting, by Leptospira icterohaemorrhagiae could help to understand the mechanism(s) responsible for the activation of intravascular coagulation sometimes associated with leptospirosis. PMID- 7187349 CU - 91 SO - G Batteriol Virol Immunol 1982 Jan-Jun;75(1-6):3-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 84017084 AU - Sulzer K AU - Pope V AU - Rogers F TI - New leptospiral serotypes (serovars) from the Western Hemisphere isolated during 1964 through 1970. LA - Eng MH - Animal MH - Animals/*microbiology MH - Animals, Wild/*microbiology MH - Central America MH - Human MH - Jamaica MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/microbiology MH - Mammals/microbiology MH - Serotyping PT - JOURNAL ARTICLE DA - 831123 DP - 1982 Jan-Mar IS - 0034-9771 TA - Rev Latinoam Microbiol PG - 15-7 CY - MEXICO IP - 1 VI - 24 JC - SEP EM - 8401 PMID- 7186673 CU - 90 SO - Rev Latinoam Microbiol 1982 Jan-Mar;24(1):15-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83251572 TI - Guidelines for the control of leptospirosis. LA - Eng MH - Adult MH - Agriculture MH - Animal MH - Animals, Domestic/microbiology MH - Cats MH - Cattle MH - Dogs MH - Female MH - Horses/microbiology MH - Human MH - Leptospira/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/diagnosis/microbiology/*prevention & control/transmission/veterinary MH - Male MH - Mice MH - Rats MH - Rodent Control MH - Sheep/microbiology MH - Swine/microbiology MH - Weil's Disease/prevention & control PT - JOURNAL ARTICLE DA - 830811 DP - 1982 IS - 0303-7878 TA - WHO Offset Publ PG - 1-171 SB - M CY - SWITZERLAND IP - 67 JC - YA4 EM - 8310 PMID- 7184280 NI - A SO - WHO Offset Publ 1982;(67):1-171 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 83161573 AU - Yamagishi A TI - [Ultrastructural study on the cellular injury in various organs induced by experimental leptospirosis] LA - Jpn MH - Animal MH - English Abstract MH - Female MH - Guinea Pigs MH - Kidney/*ultrastructure MH - Liver/*ultrastructure MH - Lung/*ultrastructure MH - Male MH - Microscopy, Electron MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 830527 DP - 1982 IS - 0048-0444 TA - Nippon Ika Daigaku Zasshi PG - 824-32 CY - JAPAN IP - 6 VI - 49 JC - HRD EM - 8307 PMID- 7166590 EA - A SO - Nippon Ika Daigaku Zasshi 1982;49(6):824-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82283230 AU - Nicolescu M AU - Pop A AU - Andreescu N AU - Marinca F TI - The macroscopic agglutination reaction with Leptospira biflexa antigens used as a screening test for the human leptospirosis. LA - Eng MH - *Agglutination Tests MH - Antigens/analysis MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis RN - 0 (Antigens) PT - JOURNAL ARTICLE DA - 821012 DP - 1982 Jan-Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 5-10 CY - ROMANIA IP - 1 VI - 41 JC - 8EM EM - 8212 PMID- 7115056 CU - 91 SO - Arch Roum Pathol Exp Microbiol 1982 Jan-Mar;41(1):5-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82283224 AU - Nicolescu M AU - Andreescu N AU - Lupan E AU - Pop A TI - The serological diagnosis of leptospirosis in domestic animals by the macroscopic agglutination test with Patoc antigen. LA - Eng MH - *Agglutination Tests MH - Animal MH - Animals, Domestic MH - Cattle MH - Dogs MH - Horses MH - Leptospirosis/diagnosis/*veterinary MH - Sheep MH - Swine PT - JOURNAL ARTICLE DA - 821012 DP - 1982 Jan-Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 11-3 CY - ROMANIA IP - 1 VI - 41 JC - 8EM EM - 8212 PMID- 7115055 SO - Arch Roum Pathol Exp Microbiol 1982 Jan-Mar;41(1):11-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82227124 AU - Cinco M AU - Banfi E AU - Soranzo MR TI - Leptospires macrophage interactions. LA - Eng MH - Blood Bactericidal Activity MH - Human MH - Leptospira/*immunology MH - Macrophages/microbiology/*physiology MH - Phagocytosis PT - JOURNAL ARTICLE DA - 820814 DP - 1982 IS - 0065-2598 TA - Adv Exp Med Biol PG - 167-74 SB - M CY - UNITED STATES VI - 141 JC - 2LU EM - 8210 PMID- 7090911 SO - Adv Exp Med Biol 1982;141:167-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [59 medline neighbors] UI - 82213331 AU - McIntosh N AU - Madhavan T TI - Zoonoses at Henry Ford Hospital: clinical, epidemiologic, and therapeutic aspects. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Brucellosis/diagnosis MH - Case Report MH - Cats MH - Colorado Tick Fever/diagnosis MH - Dogs MH - Female MH - Human MH - Leptospirosis/diagnosis MH - Male MH - Michigan MH - Middle Age MH - Ornithosis/diagnosis MH - Pasteurella Infections/diagnosis MH - Penicillins/therapeutic use MH - Pregnancy MH - Pyrimethamine/therapeutic use MH - Relapsing Fever/diagnosis MH - Tetracycline/therapeutic use MH - Toxoplasmosis/diagnosis MH - Zoonoses/*diagnosis/drug therapy/epidemiology RN - 0 (Penicillins) RN - 58-14-0 (Pyrimethamine) RN - 60-54-8 (Tetracycline) PT - JOURNAL ARTICLE DA - 820807 DP - 1982 IS - 0018-0416 TA - Henry Ford Hosp Med J PG - 7-10 CY - UNITED STATES IP - 1 VI - 30 JC - G63 EM - 8210 PMID- 7085343 CU - 92 SO - Henry Ford Hosp Med J 1982;30(1):7-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 82213330 AU - Madhavan T TI - Zoonoses in modern medical practice. LA - Eng MH - Adult MH - Animal MH - Brucellosis/epidemiology MH - Carrier State/*epidemiology MH - Cats MH - Colorado Tick Fever/epidemiology MH - Dogs MH - Female MH - Human MH - Infant, Newborn MH - Leptospirosis/epidemiology MH - Michigan MH - Pregnancy MH - Rats MH - Toxoplasmosis/epidemiology MH - United States MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 820807 DP - 1982 IS - 0018-0416 TA - Henry Ford Hosp Med J PG - 4-6 CY - UNITED STATES IP - 1 VI - 30 JC - G63 EM - 8210 PMID- 7085342 CU - 90 SO - Henry Ford Hosp Med J 1982;30(1):4-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 82130882 AU - Viazitskii PO AU - Kozlov GK AU - Shinkariuk SS TI - [Clinical x-ray changes in the lungs in leptospirosis] LA - Rus MH - Adult MH - Case Report MH - Human MH - Jaundice/radiography MH - Leptospirosis/*radiography MH - Lung/*radiography MH - Male MH - Time Factors PT - JOURNAL ARTICLE DA - 820422 DP - 1982 Jan IS - 0300-9114 TA - Voen Med Zh PG - 60-2 CY - USSR IP - 1 JC - XGS EM - 8206 PMID- 7058656 CU - 90 TT - Kliniko-rentgenologicheskie izmeneniia v legkikh pri leptospiroze. SO - Voen Med Zh 1982 Jan;(1):60-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [96 medline neighbors] UI - 82263066 AU - Borcic B AU - Kovacic H AU - Sebek Z AU - Aleraj B AU - Tvrtkovic N TI - Small terrestrial mammals as reservoirs of leptospires in the Sava Valley (Croatia). LA - Eng MH - Animal MH - Disease Reservoirs/*veterinary MH - Leptospira/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Mammals MH - Microtinae/microbiology MH - Muridae/microbiology MH - Rodent Diseases/*epidemiology MH - Yugoslavia PT - JOURNAL ARTICLE DA - 821021 DP - 1982 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 177-82 SB - M CY - CZECHOSLOVAKIA IP - 2 VI - 29 JC - F2T AA - Author EM - 8212 AB - Small mammals trapped in seven sites along the river Sava in Croatia were examined for leptospiral infection by renoculture and serological methods. Of the 1749 animals caught 702 were examined by renoculture method and 626 were tested by microagglutination-lysis. The dominant animals species caught were Microtus arvalis (672 animals) and Apodemus agrarius (552 animals). Of the 115 strains of leptospires isolated the dominant serotypes were L. grippotyphosa (40) and L. pomona (35). Five strains of L. sejroe, 9 strains of L. australis, 1 strain of L. bataviae and 25 undetermined strains were isolated, the infection rate ranging from 3 to 32%. Serologic evidence of infection was demonstrated in 91 animals, the prevalence ranging from 0 to 43% of animals depending on the trapping site. Specific agglutinins most frequently encountered were those against L. pomona (50) and L. grippotyphosa (26), though agglutinins against L. jalna (5), L. bataviae (4), L. bratislava (3) etc., were also found. A high degree if association between L. grippotyphosa and the common vole as well as between L. pomona and the field mouse was found indicating that as far as these two types of leptospires are concerned the Sava valley may be considered as their vast natural focus. It was also concluded that wild small mammals in this region of Croatia may be a source of leptospiral infection for the local population as well as for outdoor-reared domestic animals (swine, bovine). PMID- 7049871 CU - 90 SO - Folia Parasitol (Praha) 1982;29(2):177-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [93 medline neighbors] UI - 82175765 AU - Tatlock H TI - Clarification of the cause of Fort Bragg fever (pretibial fever) - January 1982. LA - Eng MH - Animal MH - Cattle MH - Child MH - Diagnosis, Differential MH - Fever/etiology/history MH - Human MH - Leg Dermatoses/history MH - Legionnaires' Disease/history MH - Leptospirosis/*history MH - Military Medicine/*history MH - North Carolina MH - Virus Diseases/etiology/*history PT - BIOGRAPHY PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 820621 DP - 1982 Jan-Feb IS - 0162-0886 TA - Rev Infect Dis PG - 157-8 SB - M CY - UNITED STATES IP - 1 VI - 4 JC - SXN EM - 8208 PMID- 7041223 CU - 96 PS - Tatlock H SO - Rev Infect Dis 1982 Jan-Feb;4(1):157-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [42 medline neighbors] UI - 82119661 AU - Altamura RF TI - Children, pets, and disease. LA - Eng MH - Animal MH - Animal Diseases/prevention & control/therapy/*transmission MH - *Animals, Domestic MH - Brucellosis/veterinary MH - Cats MH - Cattle MH - Child MH - Cryptococcosis/veterinary MH - Dirofilariasis/veterinary MH - Dogs MH - Echinococcosis/veterinary MH - Histoplasmosis/veterinary MH - Horses MH - Human MH - Larva Migrans/veterinary MH - Larva Migrans, Visceral/veterinary MH - Leptospirosis/veterinary MH - Oxyuriasis/veterinary MH - Pigeons MH - Risk MH - Salmonella Infections, Animal/transmission MH - Swine MH - Tinea/veterinary MH - *Zoonoses PT - JOURNAL ARTICLE PT - REVIEW DA - 820422 DP - 1982 Jan IS - 0098-6151 TA - J Am Osteopath Assoc PG - 334-40 CY - UNITED STATES IP - 5 VI - 81 JC - G90 EM - 8206 RF - 11 PMID- 7035416 CU - 90 SO - J Am Osteopath Assoc 1982 Jan;81(5):334-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 82251171 AU - Cacciapuoti B AU - Nuti M AU - Pinto A AU - Sabrie AM TI - Human leptospirosis in Somalia: a serological survey. LA - Eng MH - Adolescence MH - Adult MH - Antibodies, Bacterial/analysis MH - Cross-Sectional Studies MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Residence Characteristics MH - Somalia RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820910 DP - 1982 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 178-82 SB - M CY - ENGLAND IP - 2 VI - 76 JC - WBU AA - Author EM - 8211 AB - Sera from Somalis of both sexes between the ages of 16 and 60 were examined for leptospiral agglutinins. 37% of 105 apparently healthy individuals living in the arid Mogadishu area were positive, as were 64% of 107 schistosomiasis patients living in two villages on the Shabeele River (50.5% over-all). Pools of sera from similar subjects, as well as leprosy patients living on the Juba River and patients in Mogadishu hospitals with suspected viral hepatitis showed a similar prevalence rate of 56%. These figures are higher than prevelance rates for leptospiral antibodies generally found in other parts of the world, and in part may be related to the nomadic, cattle-driving existence common in Somalia. The titres of 11.2% of the positive sera examined singly indicated recent infection. Approximately twice as many subjects from the river villages as from the Mogadishu area were positive for more than one serovar, and a greater number of serovars were recorded from the villages. Antibodies to bratislava serovar, not previously recorded in Africa, were found in 57% of positive subjects, showing the highest prevalence rate among the investigated serovars. Co-antibodies to saprophytic Leptospira biflexa serovars were found in many of the sera. PMID- 6980503 CU - 91 SO - Trans R Soc Trop Med Hyg 1982;76(2):178-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 83224833 AU - Everard CO AU - Fraser-Chanpong GM AU - Hayes R AU - Bhagwandin LJ AU - Butcher LV TI - A survey of leptospirosis in febrile patients mainly from hospitals and clinics in Trinidad. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Animal MH - Animals, Domestic MH - Case Report MH - Female MH - Fever/etiology/*microbiology MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*blood/immunology MH - Male MH - Middle Age MH - Sex Factors MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 830708 DP - 1982 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 487-92 SB - M CY - ENGLAND IP - 4 VI - 76 JC - WBU AA - Author EM - 8309 AB - Acute and convalescent sera were obtained from 202 febrile patients, most of whom were admitted to or attended hospitals or clinics in northern Trinidad during the 12 months from mid-February 1977 to mid- February 1978. Laboratory tests confirmed that 10 of the patients were suffering from current leptospirosis while another 54 had serological evidence of previous leptospiral infections. Antibodies to strains of the Icterohaemorrhagiae serogroup were most commonly found, followed by those to the Hebdomadis and Autumnalis serogroups. Isolates were obtained from the blood of two and the urine of three of the 10 current cases. Four of these strains were identified as belonging to copenhageni serovar of the Icterohaemorrhagiae serogroup and one to serovar brasiliensis of the Bataviae serogroup. Seven of the patients suffering from leptospirosis were males, all rural dwellers, and all except one under 20 years of age. Two of the three female patients were over 60 years old and were urban dwellers. It was not possible to identify the sources of infection with certainty, although dogs may have been responsible for three of the Icterohaemorrhagiae and one of the Canicola infections. Of the 192 patients who were not currently infected, serological evidence of previous infection was obtained in 31 (40%) males and 23 (21%) females and was most common among farmers and rural workers. PMID- 6926766 SO - Trans R Soc Trop Med Hyg 1982;76(4):487-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83078048 AU - Ram P AU - Mataika JU AU - Metcalfe RV AU - Bettelheim KA TI - Antibody levels to Brucella abortus, Toxoplasma gondii, and Leptospira serogroups, in sera collected from healthy people in Fiji. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Antibodies/*analysis MH - Antibodies, Bacterial/*analysis MH - Brucella abortus/*immunology MH - Female MH - Fiji MH - Human MH - Leptospira/*immunology MH - Male MH - Middle Age MH - Toxoplasma/*immunology RN - 0 (Antibodies) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830214 DP - 1982 IS - 0147-9571 TA - Comp Immunol Microbiol Infect Dis PG - 397-403 SB - M CY - ENGLAND IP - 4 VI - 5 JC - DNN EM - 8304 PMID- 6816504 CU - 91 SO - Comp Immunol Microbiol Infect Dis 1982;5(4):397-403 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83036231 AU - Yanagihara Y AU - Kojima T AU - Mifuchi I TI - Hemolytic activity of Leptospira interrogans serovar canicola cultured in protein-free medium. LA - Eng MH - Animal MH - Culture Media MH - Edetic Acid/pharmacology MH - Erythrocytes/ultrastructure MH - Heat MH - Hemolysins/antagonists & inhibitors/biosynthesis/*pharmacology MH - Hydrogen-Ion Concentration MH - Leptospira interrogans/*growth & development MH - Rabbits MH - Sheep RN - 0 (Culture Media) RN - 0 (Hemolysins) RN - 60-00-4 (Edetic Acid) PT - JOURNAL ARTICLE DA - 821221 DP - 1982 TA - Microbiol Immunol PG - 547-56 SB - M CY - JAPAN IP - 7 VI - 26 JC - MX7 AA - Author EM - 8302 AB - Hemolytic activity of the culture supernatant of Leptospira interrogans serovar canicola strain Moulton grown in protein-free medium was demonstrated. The activity began to appear in the late logarithmic phase of growth of the organism and reached a plateau after 2 weeks of cultivation. It was inactivated by the addition of dipotassium ethylenediaminetetraacetate, but was effectively restored by Mg2+. Hemolysis by the culture supernatant was stimulated by "hot-cold" incubation. Sleep erythrocytes treated with the culture supernatant of the organism were transformed into spherocytes, in which invagination was observed. A hemolysis inhibitor in rabbit serum was found to be in the chloroform-methanol soluble fraction of the serum. The hemolysin of Leptospira may be phospholipase C. PMID- 6813653 CU - 91 SO - Microbiol Immunol 1982;26(7):547-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 83069183 AU - Wilson JH AU - Hermann-Dekkers WM TI - Experiments with a homologous, inactivated canine parvovirus vaccine in vaccination programmers for dogs. LA - Eng MH - Adenoviruses, Canine/immunology MH - Animal MH - Antibodies, Viral/biosynthesis MH - Dog Diseases/*prevention & control MH - Dogs MH - Hemagglutination Inhibition Tests/veterinary MH - Immunization, Secondary/veterinary MH - Leptospira/immunology MH - Parvoviridae/*immunology MH - Safety MH - Vaccination/veterinary MH - Viral Vaccines/*immunology MH - Virus Diseases/prevention & control/*veterinary RN - 0 (Antibodies, Viral) RN - 0 (Viral Vaccines) PT - JOURNAL ARTICLE DA - 830119 DP - 1982 IS - 0165-2176 TA - Vet Q PG - 108-16 SB - M CY - NETHERLANDS IP - 3 VI - 4 JC - XBT AA - Author EM - 8303 AB - The significance of canine parvovirus (CPV) infections as a permanent threat susceptible dogs, in particular pups, made the authors develop three liquid homologous inactivated adjuvant CPV vaccines that were compatible with existing canine vaccines and could be incorporated in current vaccination programmes. On vaccine (Kavak Parvo) contained only the CPV component, the second product (Kavak i-LP) also contained two inactivated leptospiral antigens, and the third vaccine (Kavak i-HLP) contained in addition an inactivated canine hepatitis virus. This paper reports on the studies conducted to test the safety and efficacy of the three products. They were used as such and as diluents for freeze dried vaccines containing live attenuated measles, distemper, and hepatitis viruses. The study was performed in a breeding kennel where all dogs were free from CPV antibodies and the nonvaccinated sentinels remained so for the course of the study. All vaccines proved to be safe in dogs of all ages, including pregnant bitches. The efficacy of the CPV component was studied both by monitoring antibody titres for more than a year and by challenge exposure of some dogs to virulent CPV. The results obtained from these studies prove that the CPV component used in the three vaccines can be incorporated as indicated in the recommended canine vaccination programmes. The observations that the inactivated CPV and hepatitis components do induce an active immunity in pups that are still protected by low levels of maternally derived antibodies against these viruses, make those vaccines very suitable in breeding kennels. Additional studies on a comparative basis are being continued in edemically CPV infected breeding kennels to quantify the significance of these observations in these special conditions. PMID- 6293155 CU - 93 SO - Vet Q 1982;4(3):108-16 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83075563 AU - Artiushin SK AU - Kiktenko VS AU - Ezhov GI AU - Lysenko AM TI - [Nucleotide composition, genome size and homologies in the DNA of Leptospira of the Armenica serogroup] LA - Rus MH - Armenia MH - Chemistry, Physical MH - DNA, Bacterial/*analysis MH - *Genes, Bacterial MH - Leptospira/classification/*genetics MH - Nucleotides/*analysis MH - Sewage MH - Water Microbiology RN - 0 (DNA, Bacterial) RN - 0 (Nucleotides) PT - JOURNAL ARTICLE DA - 830225 DP - 1982 IS - 0470-4606 TA - Biol Nauki PG - 19-21 SB - M CY - USSR IP - 10 JC - A3B EM - 8304 PMID- 6216921 CU - 92 TT - Nukleotidnyi sostav, razmer genoma i gomologii v DNK leptospir serogruppy Armenica. SO - Biol Nauki 1982;(10):19-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82243526 AU - Peklo GN TI - [Use of rubber stoppers for test tubes containing culture media growing Leptospira] LA - Rus MH - Bacteriological Techniques/*instrumentation MH - Comparative Study MH - Culture Media MH - Leptospira/*growth & development MH - Rubber RN - 0 (Culture Media) RN - 9006-04-6 (Rubber) PT - JOURNAL ARTICLE DA - 820924 DP - 1982 IS - 0023-6748 TA - Lab Delo PG - 313 CY - USSR IP - 5 JC - KYU EM - 8211 PMID- 6178898 CU - 95 TT - Ispol'zovanie rezinovykh probok dlia probirok s pitatel'noi sredoi pri vyrashchivanii leptospir. SO - Lab Delo 1982;(5):313 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 82146909 AU - Volina EG AU - Sarukhanova LE AU - Sheliastina NN TI - [Change in the dynamics of Leptospira colony formation on media containing tween-80] LA - Rus MH - Cell Division/drug effects MH - Comparative Study MH - Culture Media/metabolism/*pharmacology MH - English Abstract MH - Fatty Acids/metabolism MH - Leptospira/*growth & development/metabolism MH - Polysorbates/*pharmacology RN - 0 (Culture Media) RN - 0 (Fatty Acids) RN - 0 (Polysorbates) PT - JOURNAL ARTICLE DA - 820512 DP - 1982 IS - 0023-6748 TA - Lab Delo PG - 52-4 CY - USSR IP - 1 JC - KYU EM - 8207 PMID- 6174794 CU - 95 TT - Izuchenie dinamiki formirovaniia kolonii leptospir na sredakh, soderzhashchikh tvin-80. EA - A SO - Lab Delo 1982;(1):52-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82146908 AU - Kiktenko VS AU - Volina EG AU - Sarukhanova LE TI - [Leptospira culture on solid nutrient media using the agar layer method] LA - Rus MH - Agar MH - Anaerobiosis MH - Bacteriological Techniques MH - Culture Media/*pharmacology MH - Leptospira/*growth & development MH - Time Factors RN - 0 (Culture Media) RN - 9002-18-0 (Agar) PT - JOURNAL ARTICLE DA - 820512 DP - 1982 IS - 0023-6748 TA - Lab Delo PG - 50-2 ] CY - USSR IP - 1 JC - KYU EM - 8207 PMID- 6174793 CU - 95 TT - Kul'tivirovanie leptospir na plotnykh pitatel'nykh sredakh metodom agarovykh sloev. SO - Lab Delo 1982;(1):50-2 ] ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 82200489 AU - Dikken H AU - Timmer VE AU - Njenga R TI - Three new leptospiral serovars from Kenya. LA - Eng MH - Agglutination Tests MH - Animal MH - Kenya MH - Leptospira/*classification/isolation & purification MH - Rodentia/microbiology MH - Serotyping PT - JOURNAL ARTICLE DA - 820708 DP - 1981 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 343-6 SB - M CY - NETHERLANDS IP - 4 VI - 33 JC - WGJ AA - Author EM - 8209 AB - Three new serovars isolated from rodents in Kenya are described. The strains were investigated by the 'classical' comparative cross- agglutinin absorption test method. In the Tarassovi serogroup the new serovar kanana with reference strain Kwale is proposed and in the Autumnalis group the new serovar lambwe with reference strain Lambwe. The new serovar kenya with reference strain Njenga seems to have a position in between the Ballum and Ranarum serogroup. PMID- 7342381 SO - Trop Geogr Med 1981 Dec;33(4):343-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 82200488 AU - Dikken H AU - Adinarayanan N AU - Timmer VE TI - A new leptospiral serovar from India in the Javanica serogroup. LA - Eng MH - Agglutination Tests MH - Animal MH - India MH - Leptospira/*classification/isolation & purification MH - Male MH - Muridae/microbiology MH - Serotyping PT - JOURNAL ARTICLE DA - 820708 DP - 1981 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 339-41 SB - M CY - NETHERLANDS IP - 4 VI - 33 JC - WGJ AA - Author EM - 8209 AB - A new serovar in the Javanica serogroup is described after parallel investigation by the 'classical' comparative cross-agglutinin absorption test method and by a method derived from factor analysis. The strain was isolated from a bandicoot (Bandicota bengalensis) trapped in Mannuthy, Trichur, India. The serovar name menoni with reference strain Kerala, is proposed. PMID- 7342380 SO - Trop Geogr Med 1981 Dec;33(4):339-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 82180246 AU - Thiermann AB TI - Use of solid medium for isolation of leptospires of the Hebdomadis serogroup from bovine milk and urine. LA - Eng MH - Animal MH - Cattle/*microbiology MH - Comparative Study MH - *Culture Media MH - Female MH - Fluorouracil MH - Hamsters MH - Leptospira interrogans/growth & development/*isolation & purification MH - Mesocricetus/microbiology MH - Milk/*microbiology MH - Polysorbates MH - Urine/*microbiology RN - 0 (Culture Media) RN - 0 (Polysorbates) RN - 51-21-8 (Fluorouracil) PT - JOURNAL ARTICLE DA - 820621 DP - 1981 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2143-5 SB - M CY - UNITED STATES IP - 12 VI - 42 JC - 40C AA - Author EM - 8208 AB - Leptospira interrogans serovars hardjo and szwajizak were isolated from the milk of experimentally infected cows only when using bovine albumin polysorbate-80 solid medium. Semisolid media, with and without the addition of 5-fluorouracil, and hamster inoculations were also used in the isolation attempts. These cultural isolation methods were also compared using cows' urine. Semisolid medium with 5-fluorouracil proved to be the most successful. However, the other methods were satisfactory, with solid medium having the lowest percentage of cultural isolations. PMID- 7340582 CU - 92 SO - Am J Vet Res 1981 Dec;42(12):2143-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 82119743 AU - Collins MT AU - Gallegos TA AU - Reif JS AU - Adrian WT TI - Seroepidemiology of Leptospira interrogans serovar hardjo in Colorado antelope and cattle. LA - Eng MH - Animal MH - *Antelopes/microbiology MH - *Artiodactyla/microbiology MH - Cattle/microbiology MH - Cattle Diseases/*epidemiology MH - Colorado MH - Leptospira interrogans/isolation & purification MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. MH - Weil's Disease/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 820412 DP - 1981 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1136-9 SB - M CY - UNITED STATES IP - 11 VI - 179 JC - HAV AA - Author EM - 8206 AB - A seroepidemiologic study was conducted to determine the prevalence of Leptospira interrogans serovar hardjo infection in Colorado cattle and antelope. Sera were tested by the microscopic agglutination test, using a standard battery of 12 antigens as well as 4 additional serovars of the Hebdomadis serogroup: hardjo, szwajizak, sejroe, and balcanica. Sera from 1,856 cattle and 544 antelope were tested. In both populations, the predominant serovar detected was hardjo; hardjo titers greater than or equal to 1:400 were found in 3.2% of the cattle and 3.6% of antelope. A positive correlation was found to exist between serologic evidence of infection in cattle and the presence of antelope. In counties with presumably infected antelope, 5.6% of cattle sera reacted to hardjo; in counties with uninfected antelope, 2.6% of cattle tested were seropositive for hardjo; where no antelope existed, titers of greater than or equal to 1:400 were not detected. PMID- 7327994 CU - 90 SO - J Am Vet Med Assoc 1981 Dec 1;179(11):1136-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 82076562 AU - Hathaway SC AU - Blackmore DK TI - Ecological aspects of the epidemiology of infection with leptospires of the Ballum serogroup in the black rat (Rattus rattus) and the brown rat (Rattus norvegicus) in New Zealand. LA - Eng MH - Animal MH - Leptospirosis/epidemiology/*veterinary MH - Muridae/*microbiology MH - New Zealand MH - Rats/*microbiology MH - Rodent Diseases/*epidemiology MH - Serodiagnosis MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 820225 DP - 1981 Dec IS - 0022-1724 TA - J Hyg (Lond) PG - 427-36 SB - M CY - ENGLAND IP - 3 VI - 87 JC - IEF AA - Author EM - 8204 AB - Epidemiological aspects of infection with leptospires of the Ballum serogroup in black rats (Rattus rattus) and brown rats (Rattus norvegicus) are described. Rats inhabiting a variety of habitats were investigated and isolates identifed as belonging to the Ballum serogroup were obtained from 21 of 61 black rats (34%) and 63 of 243 brown rats (26%). The high level of endemic ballum serogroup infection in these species reported here has not been described in other countries. A statistical relationship was shown between the prevalence of infection in brown rat populations and population density but this was not evident for black rats. Epidemiological data indicates that the black rat is a maintenance host for leptospires of the Ballum serogroup in New Zealand. The brown rat does not appear to be an efficient maintenance host for these leptospires, however endemic infection can be maintained in high-density populations inhabiting synanthropic foci. An hypothesis of 'competitive exclusion' (preferential maintenance of a particular serovar by a host species) is introduced with regard to leptospiral infection in brown rats. It is concluded that the establishment and maintenance of an endemic focus of leptospirosis is dependant on: introduction of a particular serovar; a suitable host; and a suitable host habitat. Within a maintenance population direct transmission appears to be more important than indirect transmission via the environment. PMID- 7310125 CU - 88 SO - J Hyg (Lond) 1981 Dec;87(3):427-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 82178457 AU - Plascencio WY AU - Yanagawa R AU - Ueno K TI - Correlation of virulence, susceptibility to leptospiricidal activity test mediated by antiserum plus complement and colonial morphology of five lines of a strain of Leptospira interrogans serovar copenhageni. LA - Eng MH - Animal MH - *Blood Bactericidal Activity MH - Comparative Study MH - Complement MH - Culture Media MH - Guinea Pigs MH - Hamsters MH - Immune Sera MH - Leptospira interrogans/cytology/immunology/*pathogenicity MH - Support, Non-U.S. Gov't RN - 0 (Culture Media) RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 820614 DP - 1981 Dec TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 230-6 SB - M CY - GERMANY, WEST IP - 2 VI - 251 JC - Y5N AA - Author EM - 8208 AB - Correlation of virulence, susceptibility to leptospiricidal activity test mediated by antiserum plus complement (LAT) and colonial morphology was investigated using five lines of Leptospira interrogans serovar copenhageni Shibaura. Line No. 2, a moderately virulent strain, passaged in guinea pigs for 24 successive times caused occasional death of guinea pigs. Leptospiras recovered from deceased animals were characterized by decreased susceptibility to LAT and predominance of hazy colonies upon culture. Leptospiras recovered from surviving guinea pigs were of increased susceptibility to LAT and grew predominantly in non-hazy colonies. Virulent line No. 1 subjected to passage through liquid medium for 20 successive times resulted in a slight decrease in virulence and slight increase in susceptibility to LAT, but the predominance of hazy colonies upon culture was invariable. The other three lines, Nos. 3, 4 and 5 which have been maintained for more than 10 years by passage through different media respectively, were avirulent, susceptible to LAT and produced only non-hazy colonies. PMID- 7200304 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1981 Dec;251(2):230-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82079569 AU - Landini S AU - Coli U AU - Lucatello S AU - Bazzato G TI - Plasma exchange in severe leptospirosis [letter] LA - Eng MH - Human MH - Leptospirosis/*therapy MH - *Plasma Exchange PT - LETTER DA - 820212 DP - 1981 Nov 14 IS - 0140-6736 TA - Lancet PG - 1119-20 SB - A SB - M CY - ENGLAND IP - 8255 VI - 2 JC - L0S EM - 8204 PMID- 6118571 CU - 94 SO - Lancet 1981 Nov 14;2(8255):1119-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 82079558 AU - Lessa I AU - Cortes E TI - Cerebrovascular accident as a complication of leptospirosis [letter] LA - Eng MH - Cerebral Hemorrhage/*etiology MH - Human MH - Weil's Disease/*complications PT - LETTER DA - 820212 DP - 1981 Nov 14 IS - 0140-6736 TA - Lancet PG - 1113 SB - A SB - M CY - ENGLAND IP - 8255 VI - 2 JC - L0S EM - 8204 PMID- 6118561 CU - 94 SO - Lancet 1981 Nov 14;2(8255):1113 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 82080473 AU - Penschuck C AU - Denich D AU - Lutje HC TI - [Simultaneous bilateral rupture of the quadriceps (author's transl)] LA - Ger MH - Aged MH - Case Report MH - Diagnosis, Differential MH - English Abstract MH - Human MH - Knee Injuries/radiography/*surgery MH - Male MH - Rupture MH - Tendon Injuries/radiography/*surgery PT - JOURNAL ARTICLE DA - 820222 DP - 1981 Nov 13 IS - 0341-3098 TA - MMW Munch Med Wochenschr PG - 1750-2 CY - GERMANY, WEST IP - 46 VI - 123 JC - NMM AA - Author EM - 8204 AB - Simultaneous bilateral rupture of the quadriceps has several causative pathogenetic factors. On the one hand there is diabetes with macro- and microangiopathy, on the other hand acute and chronic inflammatory processes such as spotted fever and leptospirosis, dysentery and hepatitis are worth mentioning. It is also interesting that the history contains statements on an Osgood-Schlatter disease in the left knee and a suspected meniscus lesion during the war years. The daily bending of the knee by this relatively old patient must be seen as a chronic lesion of over-strain. PMID- 6796843 CU - 91 TT - Simultanter beidseitiger Riss der Quadrizepssehne. EA - A SO - MMW Munch Med Wochenschr 1981 Nov 13;123(46):1750-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 82069583 AU - Lee RE AU - Terry SI AU - Walker TM AU - Urquhart AE TI - The chest radiograph in leptospirosis in Jamaica. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Female MH - Human MH - Leptospirosis/*radiography MH - Lung/*radiography MH - Male MH - Middle Age MH - Pleural Effusion/radiography MH - Prognosis MH - Weil's Disease/radiography PT - JOURNAL ARTICLE DA - 820212 DP - 1981 Nov IS - 0007-1285 TA - Br J Radiol PG - 939-43 SB - A SB - M CY - ENGLAND IP - 647 VI - 54 JC - B28 AA - Author EM - 8204 AB - A consecutive series of 44 patients with proven leptospirosis was studied to document the radiographic pulmonary abnormalities, assess their prevalence, correlate them with the clinical signs and symptoms and determine their prognostic significance. Abnormalities were found in ten patients (23%), this prevalence being less than previously noted. The abnormalities shown were non-segmental opacification (consolidation-eight cases), basal linear opacities (collapse-five cases) and pleural effusions (four cases). The first radiographic demonstration of a large pleural effusion in leptospirosis is recorded. Non-jaundiced patients had a higher prevalence (43%) of these abnormalities than jaundiced (13%). No other correlation with clinical signs or symptoms was found. The presence of these abnormalities had no prognostic significance. It is concluded that the presence of radiographic pulmonary abnormality in in-patients with leptospirosis is common. These abnormalities are non-specific and can mimic other diseases leading to diagnostic difficulty. Such abnormalities may be extensive in the absence of clinical signs and symptoms. PMID- 7306765 SO - Br J Radiol 1981 Nov;54(647):939-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [168 medline neighbors] UI - 82198976 AU - Little TW AU - Parker BN AU - Stevens AE AU - Hathaway SC AU - Markson LM TI - Inapparent infection of sheep in Britain by leptospires of the Australis serogroup. LA - Eng MH - Animal MH - England MH - Female MH - Kidney/microbiology MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/*veterinary MH - Serotyping/veterinary MH - Sheep MH - Sheep Diseases/*microbiology MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 820708 DP - 1981 Nov IS - 0034-5288 TA - Res Vet Sci PG - 386-7 SB - M CY - ENGLAND IP - 3 VI - 31 JC - R7D EM - 8209 PMID- 7200631 CU - 85 SO - Res Vet Sci 1981 Nov;31(3):386-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82205833 AU - Swan RA AU - Williams ES AU - Taylor EG TI - Clinical and serological observations on horses with suspected leptospirosis [letter] LA - Eng MH - Animal MH - Endophthalmitis/diagnosis/*veterinary MH - Female MH - Horse Diseases/*diagnosis MH - Horses MH - Leptospirosis/diagnosis/*veterinary MH - Male PT - LETTER DA - 820719 DP - 1981 Nov IS - 0005-0423 TA - Aust Vet J PG - 528-9 SB - M CY - AUSTRALIA IP - 11 VI - 57 JC - 9IE EM - 8209 PMID- 6979332 CU - 91 SO - Aust Vet J 1981 Nov;57(11):528-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 82082609 AU - Charon NW AU - Lawrence CW AU - O'Brien S TI - Movement of antibody-coated latex beads attached to the spirochete Leptospira interrogans. LA - Eng MH - Antibodies MH - Cell Movement MH - *Latex MH - Leptospira interrogans/*physiology MH - Microspheres MH - Mutation MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, P.H.S. RN - 0 (Antibodies) RN - 0 (Latex) PT - JOURNAL ARTICLE ID - DE 04645/DE/NIDR DA - 820212 DP - 1981 Nov IS - 0027-8424 TA - Proc Natl Acad Sci U S A PG - 7166-70 SB - M CY - UNITED STATES IP - 11 VI - 78 JC - PV3 AA - Author EM - 8204 AB - Antibody-coated latex beads (Ab-beads) were attached to Leptospira interrogans serovars illini 3055 and icterohaemorrhagiae SC1157. The movement of the Ab-beads relative to the motion of the cells was observed by direct darkfield microscopy or was recorded on videotape. When the Ab-beads were attached to the front end of motile cells, the Ab-beads were displaced towards the back end of the cells. When the cells reversed direction, the Ab-beads also reversed direction. A number of hypotheses were proposed and tested to account for this Ab- bead displacement. The one best supported by the evidence states that the Ab-beads are attached to antigens of the outer membrane sheath. These antigens are dragged laterally through the sheath due to the forward motion of the cells and the retarding forces of the medium acting on the beads. The results obtained provide information on the nature of the outer membrane sheath of L. interrogans, the basis for certain movements of spirochetes, and insight on how spirochetes attach to eukaryotic cells and tissues. In addition, the results indicate that antigens can move laterally through membranes as rapidly as 11 micrometers/sec. PMID- 6947280 CU - 96 SO - Proc Natl Acad Sci U S A 1981 Nov;78(11):7166-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82075381 AU - Mavromichalis J AU - Skidmore S AU - Tsilikouna-Athanassiadou P AU - Sklavounou-Tsourouktsoglou S AU - Manios S TI - Virological and serological study in children hospitalized for acute hepatitis (detection of HBsAg, HAAg, anti-HAV and specific IgM-anti- HAV). LA - Eng MH - Adolescence MH - Antibodies, Viral/*analysis MH - Antigens, Viral/*analysis MH - Child MH - Child, Preschool MH - Greece MH - Hepatitis A/*diagnosis/immunology MH - Hepatitis B/*diagnosis/immunology MH - Hepatitis B Antibodies/analysis MH - Hepatitis B Surface Antigens/*analysis MH - Hepatitis C/diagnosis/immunology MH - Human MH - IgM/*analysis RN - 0 (Antibodies, Viral) RN - 0 (Antigens, Viral) RN - 0 (Hepatitis B Antibodies) RN - 0 (Hepatitis B Surface Antigens) PT - JOURNAL ARTICLE DA - 820222 DP - 1981 Nov IS - 0018-022X TA - Helv Paediatr Acta PG - 429-35 SB - M CY - SWITZERLAND IP - 5 VI - 36 JC - G59 AA - Author EM - 8204 AB - Serological methods were used to detect different markers of hepatitis A and B infection in a series of 36 children aged 3.5-13 years with acute viral hepatitis, hospitalized from August 1978 to October 1978. Hepatitis A was verified serologically in 30 patients (83.3%) with the demonstration of specific IgM-anti-HAV. Hepatitis B infection was serologically confirmed in only 2 patients (5.5%). After exclusion of hepatitis A and B as well as of hepatitis due to cytomegalovirus, leptospira and Epstein-Barr virus, 3 patients (8.3) were classified to have post-transfusion non-A non-B hepatitis, and 1 patient (2.5%) showed a sporadic non-A non-B hepatitis. The finding of HBsAg in 5 of 30 patients with hepatitis A suggests that the presence of HBsAg during the acute icteric phase of viral hepatitis is not sufficient for a diagnosis of HB. The presence of HAAg in one of 30 patients with HA confirms previous studies that faecal shedding of HAV stops with the appearance of jaundice. Finally, the above results establish the value of the new radioimmunoassay technique for detection of specific IgM- anti-HAV, which appears to be the best diagnostic test for hepatitis A. PMID- 6796547 CU - 91 SO - Helv Paediatr Acta 1981 Nov;36(5):429-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82109599 AU - Drankin DI AU - Godlevskaia MV AU - Abramson LA AU - Agafonova TK AU - Babushkina MS TI - [Human and animal leptospirosis in irrigated lands] LA - Rus MH - *Agriculture MH - Animal MH - Disease Reservoirs MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Rodentia MH - Russia MH - *Water MH - Weil's Disease/epidemiology/veterinary RN - 7732-18-5 (Water) PT - JOURNAL ARTICLE DA - 820322 DP - 1981 Nov IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 105-8 SB - M CY - USSR IP - 11 JC - Y9O AA - Author EM - 8205 AB - To study the influence of amelioration on the spread of leptospirosis, the survey of humans, agricultural animals and rodent was made on the territory where the irrigation system was under construction and during 2 years after the beginning of irrigation. This survey failed to establish the occurrence of significant changes in the number of rodents and their species composition, as well as in the number of agricultural animals showing the positive reaction to leptospirosis. No cases of leptospirosis were registered, and during the first years after the beginning of irrigation antibodies in low titers were detected only in 4 out of 536 subjects. The results obtained in this survey suggest that during the first years of artificial irrigation the conditions for a wider spread of leptospirosis do not appear, but the final solution of this problem can be made on the basis of observations lasting for many years. RO - M:MYA PMID- 6459692 LR - 830224 CU - 92 TT - Leptospiroz liudei i zhivotnykh na oroshaemykh zemliakh. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1981 Nov;(11):105-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 82093338 AU - Rak J TI - [Problem of nephelometric assessment of Leptospira concentrations in cultures (author's transl)] LA - Cze MH - English Abstract MH - Leptospira/*cytology/growth & development MH - *Nephelometry and Turbidimetry PT - JOURNAL ARTICLE DA - 820322 DP - 1981 Nov IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 315-20 CY - CZECHOSLOVAKIA IP - 6 VI - 30 JC - CSH EM - 8205 PMID- 6459162 CU - 92 TT - Problemy nefelometrickeho urcovania koncentracie leptospir v kulture. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1981 Nov;30(6):315-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 82057638 AU - Murphy AM AU - Hunt JG TI - Retrospective diagnosis of Q fever ina country abattoir by the use of specific IgM globulin estimations. LA - Eng MH - *Abattoirs MH - Brucellosis/diagnosis MH - Female MH - Human MH - IgM/*analysis MH - Leptospirosis/diagnosis MH - Male MH - Occupational Diseases/*diagnosis MH - Q Fever/*diagnosis MH - Retrospective Studies MH - Rural Health PT - JOURNAL ARTICLE DA - 820128 DP - 1981 Oct 3 IS - 0025-729X TA - Med J Aust PG - 326-7 SB - M CY - AUSTRALIA IP - 7 VI - 2 JC - M26 AA - Author EM - 8203 AB - Twenty-two cases of pyrexial illness which occurred amongst workers in a country abattoir were investigated retrospectively for Q fever, brucellosis, and leptospirosis. In 18, the illness was shown to be Q fever. No diagnoses were established for the other four. The demonstration of circulating Q-fever-specific IgM globulin was instrumental in establishing the diagnosis in many of the cases. PMID- 7300773 SO - Med J Aust 1981 Oct 3;2(7):326-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [85 medline neighbors] UI - 82208118 AU - Schowalter DB AU - Chalmers GA AU - Johnson GR AU - Gunson JR AU - Wynnyk WP TI - A serological survey of Leptospira interrogans serotype pomona in Alberta and Saskatchewan striped skunks and possible transmission between cattle and skunks. LA - Eng MH - Alberta MH - Animal MH - Antibodies, Bacterial/*analysis MH - Carnivora/*immunology MH - Cattle MH - Cattle Diseases/*transmission MH - Leptospira interrogans/*immunology MH - Saskatchewan MH - Skunks/*immunology MH - Support, Non-U.S. Gov't MH - Weil's Disease/transmission/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820826 DP - 1981 Oct IS - 0008-5286 TA - Can Vet J PG - 321-3 CY - CANADA IP - 10 VI - 22 JC - CLS EM - 8210 PMID- 7343072 CU - 91 SO - Can Vet J 1981 Oct;22(10):321-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 82170682 AU - Ferguson DV AU - Heidt GA TI - Survey for rabies, leptospirosis, toxoplasmosis and tularemia in striped skunks (Mephitis mephitis) from three public use areas in northwestern Arkansas. LA - Eng MH - Animal MH - Arkansas MH - *Carnivora MH - Comparative Study MH - Leptospirosis/epidemiology/*veterinary MH - Rabies/epidemiology/*veterinary MH - *Skunks MH - Toxoplasmosis, Animal/*epidemiology MH - Tularemia/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 820624 DP - 1981 Oct IS - 0090-3558 TA - J Wildl Dis PG - 515-9 SB - M CY - UNITED STATES IP - 4 VI - 17 JC - KEM AA - Author EM - 8208 AB - During a skunk eradication program in late August, 1979, 53 striped skunks (Mephitis mephitis) were removed from three public use areas on Beaver Lake, Benton and Carroll counties in northwestern Arkansas. None of the 53 animals were positive for rabies (fluorescent antibody technique) and only one of 45 (2.2%) was positive for rabies antibodies. Twenty-one of 45 animals (46.6%) tested were positive for leptospirosis; 10 of 45 (22.2%) were positive for toxoplasmosis; and none were positive for tularemia. High populations of striped skunks in public use areas could be a potentially important reservoir for several diseases affecting both humans and other animals. PMID- 7338974 CU - 90 SO - J Wildl Dis 1981 Oct;17(4):515-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 82170678 AU - Hathaway SC AU - Blackmore DK AU - Marshall RB TI - Leptospirosis in free-living species in New Zealand. LA - Eng MH - Animal MH - *Animals MH - *Animals, Wild MH - Bird Diseases/epidemiology MH - Birds MH - Comparative Study MH - Leptospirosis/epidemiology/*veterinary MH - Muridae MH - New Zealand MH - Opossums MH - Rats MH - Rodent Diseases/epidemiology MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 820624 DP - 1981 Oct IS - 0090-3558 TA - J Wildl Dis PG - 489-96 SB - M CY - UNITED STATES IP - 4 VI - 17 JC - KEM AA - Author EM - 8208 AB - A total of 1296 free-living mammals and birds of 12 species was examined for serologic and bacteriologic evidence of leptospiral infection. Endemic infection with serovar ballum was found in several introduced species of mammals. Endemic ballum infection is not recognized in the same species in Great Britain, their country of origin. Possums (Trichosurus vulpecula) were found to have a high prevalence of infection with balcanica, a serovar that has been isolated from possums in Australia and from cattle, pigs and humans in Eastern Europe. Free-living lagomorphs and deer were both serologically and bacteriologically negative. Waterfowl were bacteriologically negative, and only one serological titre was found. PMID- 7338970 CU - 90 SO - J Wildl Dis 1981 Oct;17(4):489-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82131530 AU - Volina EG AU - Bychenko BD AU - Bocharova NG TI - [Use of the enzyme-labeled antibody technic to diagnose leptospirosis] LA - Rus MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial/*immunology MH - Comparative Study MH - English Abstract MH - Enzyme-Linked Immunosorbent Assay MH - Leptospira/*immunology MH - Leptospirosis/blood/*diagnosis MH - Rabbits RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 820420 DP - 1981 Oct IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 45-8 SB - M CY - USSR IP - 10 JC - Y9O EM - 8206 PMID- 7331608 CU - 91 TT - Primenenie reaktsii enzimmechennykh antitel dlia diagnostiki leptospiroza. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1981 Oct;(10):45-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82076194 AU - Cursons RT AU - Pyke PA TI - Diffusion in gel-enzyme-linked immunosorbent assay-a new serological test for leptospirosis. LA - Eng MH - Agglutination Tests MH - Comparative Study MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - Immune Sera MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 820222 DP - 1981 Oct IS - 0021-9746 TA - J Clin Pathol PG - 1128-31 SB - A SB - M CY - ENGLAND IP - 10 VI - 34 JC - HT3 EM - 8204 PMID- 7309893 CU - 90 SO - J Clin Pathol 1981 Oct;34(10):1128-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82063703 AU - Chernokozinskii AA TI - [Epidemiology and epizootiology of leptospirosis due to circulation of various serological variants of Leptospira] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/transmission MH - *Disease Reservoirs MH - Human MH - Leptospira/*pathogenicity MH - Leptospirosis/*epidemiology/transmission/veterinary MH - Rural Health MH - Ukraine PT - JOURNAL ARTICLE DA - 820128 DP - 1981 Oct IS - 0049-6804 TA - Vrach Delo PG - 118-9 CY - USSR IP - 10 JC - XLS EM - 8203 PMID- 7303566 CU - 88 TT - K epidemiologii i epizootologii leptospirozov v sviazi s tsirkuliatsiei razlichnykh serologicheskikh variantov Leptospir. SO - Vrach Delo 1981 Oct;(10):118-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 82043344 AU - Trowbridge AA AU - Green JB 3d AU - Bonnett JD AU - Shohet SB AU - Ponnappa BD AU - McCombs WB 3d TI - Hemolytic anemia associated with leptospirosis. Morphologic and lipid studies. LA - Eng MH - Anemia, Hemolytic/*etiology MH - Case Report MH - Erythrocyte Membrane/analysis MH - Erythrocytes/pathology/ultrastructure MH - Human MH - Leptospira/metabolism MH - Leptospirosis/*complications MH - Male MH - Membrane Lipids/analysis MH - Microscopy, Electron MH - Middle Age MH - Phosphatidylethanolamines/analysis MH - Phospholipases/*biosynthesis MH - Sphingomyelins/analysis RN - EC 3.1.- (Phospholipases) RN - 0 (Membrane Lipids) RN - 0 (Phosphatidylethanolamines) RN - 0 (Sphingomyelins) PT - JOURNAL ARTICLE DA - 811221 DP - 1981 Oct IS - 0002-9173 TA - Am J Clin Pathol PG - 493-8 SB - A SB - M CY - UNITED STATES IP - 4 VI - 76 JC - 3FK AA - Author EM - 8202 AB - A case of fulminant hemolytic anemia associated with a leptospiral infection is presented with morphologic and erythrocyte lipid studies. Both the frequency and pathogenesis of anemia in human leptospirosis is poorly understood. The anemia frequently observed in Weil's syndrome has been ascribed on clinical impression to blood loss, renal failure, and/or an ill-defined hemolytic process. However, hemolytic anemia associated with leptospirosis in animals is well documented and is due to hemolysins with phospholipase activity. Our patient's erythrocyte morphologic abnormalities on bright light and electron microscopy included particles of cells and cells with a thorny or spiculated surface suggesting that the hemolytic process was due to membrane injury. Measurement of the erythrocyte membrane lipids showed reductions in sphingomyelin and phosphatidylethanolamine suggesting that the observed hemolysis and morphologic changes resulted from phospholipases produced by the infecting leptospirae. PMID- 7293971 CU - 92 SO - Am J Clin Pathol 1981 Oct;76(4):493-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [16 medline neighbors] UI - 82052781 AU - Harvey RW AU - Price TH TI - Observations on infections associated with South Wales natural waters. LA - Eng MH - Animal MH - Anthrax/*transmission MH - Human MH - Leptospirosis/*transmission MH - Paratyphoid Fever/transmission MH - Salmonella Infections/*transmission MH - Skin Diseases, Parasitic/transmission MH - Trematode Infections/*transmission MH - Typhoid/transmission MH - Wales MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 820109 DP - 1981 Oct IS - 0021-8847 TA - J Appl Bacteriol PG - 369-74 SB - M CY - ENGLAND IP - 2 VI - 51 JC - HDJ EM - 8203 PMID- 6795173 CU - 91 SO - J Appl Bacteriol 1981 Oct;51(2):369-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [68 medline neighbors] UI - 82012467 AU - Robertson MH AU - Clarke IR AU - Coghlan JD AU - Gill ON TI - Leptospirosis in trout farmers. LA - Eng MH - Animal MH - Animal Feed MH - Case Report MH - *Disease Outbreaks MH - Disease Vectors MH - *Fisheries MH - Food Contamination MH - Human MH - Male MH - Middle Age MH - Occupational Diseases/*diagnosis MH - Rats/parasitology MH - *Salmonidae MH - *Trout MH - Weil's Disease/*transmission/veterinary PT - JOURNAL ARTICLE DA - 811122 DP - 1981 Sep 19 IS - 0140-6736 TA - Lancet PG - 626-7 SB - A SB - M CY - ENGLAND IP - 8247 VI - 2 JC - L0S AA - Author EM - 8201 AB - A worker on a trout farm died from serologically confirmed leptospirosis. Four other workers at the trout farm had recently had an influenza-like illness; one had had jaundice. The man with jaundice had high leptospiral antibody titres, and two others had titres of 1/30. The remaining serum sample was negative. Family members and neighbours not associated with the farm had no detectable leptospiral antibodies. There was evidence of rat infestation around the ponds and in a shed used for storing trout food. Pond water or trout food contaminated with rat urine is believed to have been responsible for the outbreak. Another case occurred in a fish farmer elsewhere and it is thought he was infected through wading in rat polluted water with defective rubber boots. A survey to determine the incidence of leptospirosis in fish farm workers is under way. RO - M:FES PMID- 6116098 LR - 820409 CU - 94 SO - Lancet 1981 Sep 19;2(8247):626-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 82185943 TI - [Studies on the relationship between Leptospira infection and cerebrovascular diseases in adolescents (author's transl)] LA - Chi MH - Adolescence MH - Adult MH - Antibodies, Bacterial/analysis MH - Cerebrovascular Disorders/*etiology/immunology MH - Child MH - Human MH - Leptospirosis/*complications RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820719 DP - 1981 Sep TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 313-4 CY - CHINA IP - 5 VI - 15 JC - D74 EM - 8209 PMID- 7341116 CU - 91 NI - A SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1981 Sep;15(5):313-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82107080 AU - Hathaway SC AU - Little TW AU - Stevens AE TI - Serological and bacteriological survey of leptospiral infection in pigs in southern England. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Comparative Study MH - England MH - Kidney/microbiology MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - Swine MH - Swine Diseases/*immunology/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820326 DP - 1981 Sep IS - 0034-5288 TA - Res Vet Sci PG - 169-73 SB - M CY - ENGLAND IP - 2 VI - 31 JC - R7D AA - Author EM - 8205 AB - A total of 597 pigs were examined for serological and bacteriological evidence of leptospiral infection. The sample comprised 189 porkers, 205 baconers and 203 sows. Sera were tested against 17 antigens from 16 serogroups and the overall prevalence of titres was 15.7 per cent. The lowest prevalence of titres was found in porkers (10.0 per cent). The highest prevalence of titres to an individual antigen was recorded with bratislava, a member of the Australis serogroup, with 12.2 per cent of pigs positive. Copenhageni titres were present in 1.8 per cent of the sera and sporadic titres were recorded to various other antigens. Leptospires were isolated from five pigs. Four isolates were identified as belonging to the Icterohaemorrhagiae serogroup and one to the Hebdomadis serogroup. The serological to bacteriological ratio for the Icterohaemorrhagiae serogroup was 11:4. The virtual absence of titres to pomona and tarassovi, the two serovars most commonly maintained by porcine populations in other countries, confirms the results of earlier serological surveys. PMID- 7323462 CU - 91 SO - Res Vet Sci 1981 Sep;31(2):169-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82064468 AU - Soboleva GL AU - Malakhov IuA TI - [Antagonistic properties of Leptospira interrogans] LA - Rus MH - *Antibiosis MH - Leptospira interrogans/*growth & development PT - JOURNAL ARTICLE DA - 820120 DP - 1981 Sep IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 53-6 SB - M CY - USSR IP - 9 JC - Y9O EM - 8203 PMID- 7306364 TT - Antagonisticheskie svoistva Leptospira interrogans. SO - Zh Mikrobiol Epidemiol Immunobiol 1981 Sep;(9):53-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 82018824 AU - Sterling CR AU - Thiermann AB TI - Urban rats as chronic carriers of leptospirosis: an ultrastructural investigation. LA - Eng MH - Animal MH - Carrier State MH - Female MH - Kidney Tubules/pathology MH - Leptospirosis/pathology/transmission/*veterinary MH - Male MH - Rats MH - Rodent Diseases/*pathology/transmission MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE ID - RR-05384/RR/NCRR DA - 811124 DP - 1981 Sep IS - 0300-9858 TA - Vet Pathol PG - 628-37 SB - M CY - SWITZERLAND IP - 5 VI - 18 JC - XBQ AA - Author EM - 8201 AB - Kidneys of six wild-trapped, adult Norway rats with high agglutinating titers to Leptospira icterohaemmorhagiae were examined ultrastructurally. Although many leptospires were seen in the lumen of proximal kidney tubules, few changes in epithelial cells of this region were found. The predominant lesion in chronic rat leptospirosis was diffuse interstitial nephritis. Principal kidney lesions were proximal tubule cell basement membrane thickening with or without the presence of granular particles, and an interstitial response that varied from mixed hypercellular to chiefly plasmacytic. The association of leptospires with membrane-bound protein droplets of the proximal kidney tubules may be important in the maintenance of the chronic carrier state in rat leptospirosis. PMID- 7281461 CU - 96 SO - Vet Pathol 1981 Sep;18(5):628-37 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [55 medline neighbors] UI - 82064401 AU - Hovind-Hougen K AU - Ellis WA AU - Birch-Andersen A TI - Leptospira parva sp.npv.: some morphological and biological characters. LA - Eng MH - Base Composition MH - Cell Membrane/ultrastructure MH - DNA, Bacterial/analysis MH - Flagella/ultrastructure MH - Leptospira/classification/physiology/*ultrastructure MH - Organoids/ultrastructure MH - Support, Non-U.S. Gov't MH - Temperature RN - 0 (DNA, Bacterial) PT - JOURNAL ARTICLE DA - 820109 DP - 1981 Sep TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 343-54 SB - M CY - GERMANY, WEST IP - 3 VI - 250 JC - Y5N AA - Author EM - 8203 AB - Two lines of a spirochete were isolated as contaminants in a culture of a leptospire and from a bottle of uninoculated medium. Studies on morphological and biological characters led to the conclusion that these lines represent a new species of the genes Leptospira, Leptospira parva sp. nov. The morphology of the cells was rather similar to that of previously examined leptospires, but the cells were shorter and had a shorter wavelength (more tightly wound). Furthermore, the surface layer of cells of L. parva formed numerous small blebs with no apparent substructure when detached during preparation for negative staining, while the surface layer of previously studied leptospires formed cross- striated tubules under similar conditions. L. parva shows biological characteristics of both parasitic and saprophytic leptospires. The deoxyribonucleic acid base composition of cells of this organism differed from that found in leptospires, as well as from that found in cells of Leptonema illini. PMID- 7197860 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1981 Sep;250(3):343-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82208121 AU - Higgins R TI - A minireview of the pathogenesis of acute leptospirosis. LA - Eng MH - Acute Disease MH - Animal MH - Disseminated Intravascular Coagulation/etiology MH - Enterotoxins/toxicity MH - Guinea Pigs MH - Hemorrhagic Diathesis/etiology MH - Human MH - Leptospirosis/*etiology MH - Thrombocytopenia/etiology RN - 0 (Enterotoxins) PT - JOURNAL ARTICLE PT - REVIEW DA - 820826 DP - 1981 Sep IS - 0008-5286 TA - Can Vet J PG - 277-8 CY - CANADA IP - 9 VI - 22 JC - CLS EM - 8210 RF - 20 PMID- 7044515 CU - 92 SO - Can Vet J 1981 Sep;22(9):277-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 82185938 AU - Yang XZ TI - [Preliminary observations on the preservation of Leptospira in sealed ampoules (author's transl)] LA - Chi MH - *Bacteriological Techniques MH - Leptospira/*growth & development MH - Temperature PT - JOURNAL ARTICLE DA - 820719 DP - 1981 Sep TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 299-300 CY - CHINA IP - 5 VI - 15 JC - D74 EM - 8209 PMID- 7042243 CU - 90 SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1981 Sep;15(5):299-300 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 82112929 AU - Adler B AU - Faine S AU - Gordon LM TI - The enzyme-linked immunosorbent assay (ELISA) as a serological test for detecting antibodies against Leptospira interrogans serovar hardjo in sheep. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - *Enzyme-Linked Immunosorbent Assay MH - *Immunoenzyme Techniques MH - Leptospira interrogans/*immunology MH - Leptospirosis/diagnosis/*veterinary MH - Sheep MH - Sheep Diseases/*diagnosis MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820313 DP - 1981 Sep IS - 0005-0423 TA - Aust Vet J PG - 414-7 SB - M CY - AUSTRALIA IP - 9 VI - 57 JC - 9IE AA - Author EM - 8205 AB - The enzyme-liked immunosorbent assay (ELISA) was compared with the standard microscopic agglutination test (MAT) as a method for detecting antibodies against Leptospira interrogans serovar hardjo in sheep. Peak antibody levels detected by the 2 tests occurred at different times following experimental infection of sheep. In serums from flocks of sheep with naturally acquired infection there was a 95% correlation between MAT and ELISA with respect to the presence or absence of antibody to serovar hardjo, although the levels of correlation of the titres of the 2 tests was low. The 2 tests appeared to measure different antigen-antibody systems. The ELISA would be a useful test for screening large numbers of serums for antibodies to L. interrogans serovar hardjo. PMID- 7034708 CU - 91 SO - Aust Vet J 1981 Sep;57(9):414-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 82173674 AU - Hathaway SC TI - Experimental infection of the possum (Trichosurus vulpecula) with Leptospira interrogans serovar balcanica. II. A comparison of laboratory techniques for the detection of leptospiraemia and leptospiruria. LA - Eng MH - Animal MH - Blood/microbiology MH - Comparative Study MH - Hamsters MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/blood/microbiology/urine/*veterinary MH - Opossums/*microbiology MH - Support, Non-U.S. Gov't MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 820621 DP - 1981 Sep IS - 0048-0169 TA - N Z Vet J PG - 147-50 CY - NEW ZEALAND IP - 9 VI - 29 JC - OBZ EM - 8208 PMID- 6951120 CU - 88 SO - N Z Vet J 1981 Sep;29(9):147-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 81257656 AU - Zaltzman M AU - Kallenbach JM AU - Goss GD AU - Lewis M AU - Zwi S AU - Gear JH TI - Adult respiratory distress syndrome in Leptospira canicola infection. LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospira canicola MH - Leptospirosis/*complications MH - Male MH - Respiratory Distress Syndrome, Adult/*etiology PT - JOURNAL ARTICLE DA - 811025 DP - 1981 Aug 22 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 519-20 SB - M CY - ENGLAND IP - 6290 VI - 283 JC - B4X AA - Author EM - 8112 AB - A man was admitted to the Johannesburg Hospital with a history of fever, diarrhoea, and dry cough for four days. He began to produce bloodstained sputum and was found to have severe arterial hypoxaemia. Radiography showed widespread opacification over both lung fields, and the clinical and haemodynamic features were consistent with the adult respiratory distress syndrome. Serology for Leptospira canicola was positive. Despite antibiotics, supportive therapy, and ventilation the patient died. Necropsy excluded cardiac disease. This case shows that leptospirosis may cause the adult respiratory distress syndrome. PMID- 6790049 CU - 91 SO - Br Med J (Clin Res Ed) 1981 Aug 22;283(6290):519-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 82026351 AU - Catania S AU - Cirelli A AU - Traditi F AU - Vittucci P AU - Mancini R AU - Chircu LV TI - [Epidemiological, clinical and therapeutic considerations of 5 cases of leptospirosis hospitalized in the decade 1970-1979] LA - Ita MH - Adolescence MH - Adult MH - Age Factors MH - Case Report MH - Female MH - Human MH - Italy MH - Leptospirosis/diagnosis/drug therapy/*epidemiology MH - Male MH - Middle Age MH - Occupations MH - Sex Factors PT - JOURNAL ARTICLE DA - 811221 DP - 1981 Aug 15 IS - 0009-9074 TA - Clin Ter PG - 269-77 CY - ITALY IP - 3 VI - 98 JC - DKN EM - 8202 PMID- 7285538 CU - 88 TT - Considerazioni epidemiologiche, cliniche e terapeutiche su 5 casi di leptospirosi ricoverati nel decennio 1970-1979. SO - Clin Ter 1981 Aug 15;98(3):269-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 81278025 AU - Schonberg A TI - Studies on the effect of antibiotic substances on leptospires and their cultivation from material with a high bacterial count. LA - Eng MH - Antibiotics/*pharmacology MH - Chloramphenicol/pharmacology MH - Comparative Study MH - Leptospira/*drug effects MH - Leptospira canicola/*drug effects MH - Leptospira interrogans/*drug effects MH - Microbial Sensitivity Tests MH - Nalidixic Acid/pharmacology MH - Neomycin/pharmacology MH - Streptomycin/pharmacology MH - Vancomycin/pharmacology RN - 0 (Antibiotics) RN - 1404-04-2 (Neomycin) RN - 1404-90-6 (Vancomycin) RN - 389-08-2 (Nalidixic Acid) RN - 56-75-7 (Chloramphenicol) RN - 57-92-1 (Streptomycin) PT - JOURNAL ARTICLE DA - 811025 DP - 1981 Aug IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 400-6 SB - M CY - GERMANY, WEST IP - 3 VI - 249 JC - Y5P AA - Author EM - 8112 AB - Leptospira species are difficult to isolate from sperm specimens because rapid growth of the contaminant flora will kill the pathogen. The resistance of 5 Leptospira strains to 5 different antibiotics was examined with a view to an inhibition of such contaminant growth. Neomycin (10, 20, 30 mg/l), vancomycin (5, 8, 10 mg/l), nalidixic acid (50, 75, 100 mg/l), streptomycin (5, 8, 10 mg/l) and chloramphenicol (5, 10, 20 mg/l) were added separately to Korthof's culture medium containing rabbit serum. The comparative growth rates of the leptospires were evaluated. Against the control medium, all 5 antibiotics were found to have an adverse influence on the multiplication phase. In conformity with literature data, vancomycin (10 mg/l) and nalidixic acid (50 mg/l) were found to have the lowest effect. In the cases of streptomycin and chloramphenicol, there was a high reduction of the leptospiral count and even a complete lack of multiplication. A combination of vancomycin (10 mg2l) and nalidixic acid (50 mg/l) was used for the recovery of leptospires from porcine sperm. To inhibit a growth of Ps. aeruginosa, 5000 U/l polymyxin B were added. The strongly inhibitory action of polymyxin B on leptospiral growth could be eliminated by subculturing in a medium free from inhibitory substances after 2 days. PMID- 7269858 CU - 91 SO - Zentralbl Bakteriol [A] 1981 Aug;249(3):400-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 82006445 AU - Austin FE AU - Barbieri JT AU - Corin RE AU - Grigas KE AU - Cox CD TI - Distribution of superoxide dismutase, catalase, and peroxidase activities among Treponema pallidum and other spirochetes. LA - Eng MH - Borrelia/enzymology MH - Catalase/metabolism MH - Comparative Study MH - Electrophoresis, Polyacrylamide Gel MH - Leptospira/enzymology MH - Peroxidases/*metabolism MH - Spirochaeta/enzymology MH - Spirochaetales/*enzymology MH - Superoxide Dismutase/*metabolism MH - Support, U.S. Gov't, P.H.S. MH - Treponema pallidum/*enzymology RN - EC 1.11.1. (Peroxidases) RN - EC 1.11.1.6 (Catalase) RN - EC 1.15.1.1 (Superoxide Dismutase) PT - JOURNAL ARTICLE ID - AI-10982/AI/NIAID DA - 811118 DP - 1981 Aug IS - 0019-9567 TA - Infect Immun PG - 372-9 SB - M CY - UNITED STATES IP - 2 VI - 33 JC - GO7 AA - Author EM - 8201 AB - Representative members of Spirochaetales were surveyed for their content of superoxide dismutase (SOD), catalase, and peroxidase activities. Only Leptospira exhibited peroxidase activity. Obligately anaerobic cultivable Treponema and Spirochaeta possessed no SOD or peroxidative capabilities. Upon polyacrylamide gel electrophoresis, Spirochaeta aurantia, Borrelia hermsi, and five Leptospira biflexa serovars showed SOD activity associated with one electrophoretic band which was inhibited by H2O2, suggesting that they were iron-containing dismutases. These spirochetes could be distinguished by differences in relative mobilities of their SODs. SOD activity, but not catalase activity, was induced aerobically in S. aurantia. All Leptospira interrogans serovars and two L. biflexa serovars lacked significant SOD activity. These SOD-deficient strains of Leptospira, with one exception, possessed high levels of catalase activity. The Nichols strain of virulent Treponema pallidum possessed SOD and catalase activities, but lacked peroxidase activity. The SOD in T. pallidum exhibited two electrophoretic bands containing copper and zinc, and its relative mobility was identical to that of purified rabbit SOD. Immunization of sheep with purified rabbit SOD resulted in antiserum which inhibited both rabbit SOD and T. pallidum SOD assayed by spectrophotometric analysis or activity staining following polyacrylamide gel electrophoresis. In agarose gel diffusion, precipitin lines of identity were observed between purified rabbit SOD and cell extracts of T. pallidum. These data indicated that the SOD activity detected in T. pallidum was host derived. PMID- 7024127 CU - 96 SO - Infect Immun 1981 Aug;33(2):372-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 82096443 AU - Gregoretti S TI - [Leptospirosis-associated acute anemic crisis in a patient with HbS- thalassemia (author's transl)] LA - Ita MH - Adolescence MH - Anemia, Aplastic/*etiology MH - Anemia, Hemolytic/*etiology MH - Case Report MH - English Abstract MH - *Hemoglobin, Sickle MH - Hemoglobinuria/*complications MH - Human MH - Leptospirosis/*complications MH - Male MH - Thalassemia/*complications RN - 0 (Hemoglobin, Sickle) PT - JOURNAL ARTICLE DA - 820313 DP - 1981 Aug IS - 0017-6567 TA - Haematologica PG - 493-7 CY - ITALY IP - 4 VI - 66 JC - FYB EM - 8205 PMID- 6797883 CU - 92 TT - Crisi di anemizzazione acuta associata a leptospirosi in un paziente con malattia da HbS-talassemia. EA - A SO - Haematologica 1981 Aug;66(4):493-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 81280079 AU - Navarro CE AU - Kociba GJ AU - Kowalski JJ TI - Serum biochemical changes in dogs with experimental Leptospira interrogans serovar icterohaemorrhagiae infection. LA - Eng MH - Alanine Aminotransferase/blood MH - Alkaline Phosphatase/blood MH - Animal MH - Aspartate Aminotransferase/blood MH - Bilirubin/blood MH - Blood Urea Nitrogen MH - Chlorides/blood MH - Creatinine/blood MH - Dog Diseases/*blood MH - Dogs MH - Female MH - Leptospira interrogans MH - Male MH - Phosphorus/blood MH - Support, Non-U.S. Gov't MH - Weil's Disease/blood/*veterinary RN - EC 2.6.1.1 (Aspartate Aminotransferase) RN - EC 2.6.1.2 (Alanine Aminotransferase) RN - EC 3.1.3.1 (Alkaline Phosphatase) RN - 0 (Chlorides) RN - 60-27-5 (Creatinine) RN - 635-65-4 (Bilirubin) RN - 7723-14-0 (Phosphorus) PT - JOURNAL ARTICLE DA - 811025 DP - 1981 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1125-9 SB - M CY - UNITED STATES IP - 7 VI - 42 JC - 40C AA - Author EM - 8112 AB - Inoculation of 2 groups of dogs with 1 X 10(9) and 4 X 10(9) Leptospira interrogans serovar icterohaemorrhagiae produced disease varying from transient fever to uremia and death. Clinical signs of disease in the severely affected dogs were fever, dehydration, depression, and icterus. Laboratory changes in serum of infected dogs included increased urea nitrogen, creatinine, phosphorus, alkaline phosphatase, total bilirubin, aspartate aminotransferase, and alanine aminotransferase. Chloride concentration decreased in the serum of dogs with severe disease. The icterus in the infected dogs did not appear to be related to hemolytic anemia. PMID- 7271027 CU - 91 SO - Am J Vet Res 1981 Jul;42(7):1125-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81277130 AU - Tarasov VI TI - [Diagnosis and treatment of leptospirosis] LA - Rus MH - Adult MH - Antibiotics/administration & dosage MH - Diagnostic Errors MH - Diet Therapy MH - Human MH - Infusions, Parenteral MH - Leptospirosis/*diagnosis/therapy MH - Male MH - Middle Age RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 811029 DP - 1981 Jul IS - 0026-9050 TA - Voen Med Zh PG - 42-3 CY - USSR IP - 7 JC - XGS EM - 8112 RO - M:CNR PMID- 7269382 LR - 880801 CU - 91 TT - Diagnostika i lechenie leptospiroza. SO - Voen Med Zh 1981 Jul;(7):42-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 82020125 AU - Malakhov IuA AU - Soboleva GL TI - [Relation between colony shape and the antigenic, immunogenic and virulent properties of L. interrogans] LA - Rus MH - Animal MH - Clone Cells MH - English Abstract MH - Hamsters MH - Human MH - Leptospira interrogans/*growth & development/immunology/pathogenicity MH - Mesocricetus MH - Virulence PT - JOURNAL ARTICLE DA - 811124 DP - 1981 Jul IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 84-9 SB - M CY - USSR IP - 7 JC - Y9O AA - Author EM - 8201 AB - Altogether 89 Leptospira strains isolated from humans and various animal species in different regions of the USSR, as well as in other countries, and belonging to 42 serovars and 10 serological groups were studied. The growth time and yield of the cultures on 12 solid culture media were established; these criteria were used to determine the optimum solid culture medium. The dynamic study of the changes in the colonies, connected with their age, and the parameters of the colonies, typical of L. interrogans, were determined. The cloning of Leptospira was carried out, and the biological properties of the clones thus obtained, as well as those of the original culture, were compared. In this study the form of the colonies was found to depend on the antigenic, immunogenic and virulent activity of Leptospira. PMID- 7197105 CU - 90 TT - Vzaimosviaz' formy koloniis antigennymi, immunogennymi i virulentnymi svoistvami L. interrogans. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1981 Jul;(7):84-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82104718 AU - Hathaway SC TI - Leptospirosis in New Zealand: an ecological view. LA - Eng MH - Animal MH - *Animals MH - *Animals, Domestic MH - *Animals, Wild MH - Human MH - Leptospirosis/epidemiology/prevention & control/*veterinary MH - New Zealand PT - JOURNAL ARTICLE PT - REVIEW DA - 820326 DP - 1981 Jul IS - 0048-0169 TA - N Z Vet J PG - 109-12 CY - NEW ZEALAND IP - 7 VI - 29 JC - OBZ EM - 8205 RF - 54 PMID- 7033850 CU - 90 SO - N Z Vet J 1981 Jul;29(7):109-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82104721 AU - Hathaway SC TI - Experimental infection of the possum (Trichosurus vulpecula) with Leptospira interrogans serovar balcanica. I. Characteristics of infection. LA - Eng MH - Animal MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Opossums/*microbiology MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 820326 DP - 1981 Jul IS - 0048-0169 TA - N Z Vet J PG - 121-5 CY - NEW ZEALAND IP - 7 VI - 29 JC - OBZ EM - 8205 PMID- 6948232 CU - 88 SO - N Z Vet J 1981 Jul;29(7):121-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [90 medline neighbors] UI - 82104720 AU - Hathaway SC AU - Blackmore DK TI - Failure to demonstrate the maintenance of leptospires by free-living carnivores. LA - Eng MH - Animal MH - Animals/*microbiology MH - Animals, Wild/*microbiology MH - Carnivora/*microbiology MH - Cats/microbiology MH - Ferrets/microbiology MH - Leptospira/*isolation & purification MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 820326 DP - 1981 Jul IS - 0048-0169 TA - N Z Vet J PG - 115-6 CY - NEW ZEALAND IP - 7 VI - 29 JC - OBZ EM - 8205 PMID- 6948231 CU - 90 SO - N Z Vet J 1981 Jul;29(7):115-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 82018812 AU - Dvorakova L TI - [Bovine leptospirosis in the South Bohemian Region] LA - Cze MH - Abortion, Veterinary/immunology MH - Animal MH - Antibodies/analysis MH - Cattle MH - Cattle Diseases/*epidemiology MH - Czechoslovakia MH - English Abstract MH - Female MH - Leptospira/immunology MH - Leptospirosis/epidemiology/*veterinary MH - Pregnancy RN - 0 (Antibodies) PT - JOURNAL ARTICLE DA - 811124 DP - 1981 Jul IS - 0375-8427 TA - Vet Med (Praha) PG - 411-8 SB - M CY - CZECHOSLOVAKIA IP - 7 VI - 26 JC - XBP AA - Author EM - 8201 AB - In the years 1976 to 1979, 10 345 blood samples of clinically healthy cattle and aborting cows were examined; 11% of the samples contained positive antibody titers to L. grippotyphosa (7% in non-aborting cows, 3.2% in non-aborting heifers, 12% in aborting cows, 8% in aborting heifers). The samplings were repeated within the range of three weeks to three months: the antibody titer increased in 11.8% of samples, 10.9% of samples were unchanged and in 77.2% of samples the titers dropped. Out of 9918 blood samples taken after abortion, the titer 1 :800 for L. grippotyphosa occurred 269 times, titer 1 :1600 192 times, 1 :3200 61 times, 1 :6400 22 times, 1 :12800 10 times, 1 : 25 600 occurred twice. Most of the positive titers were recorded in March - 16%, in September, October and November it was about 14% and in the other months the value was still lower. In stables with a greater per cent of the positive titers of antibodies to L. grippotyphosa, mastitis of obscure etiology occurred, along with abortions at the end and beginning of gravidity. During incidental slaughters in slaughter- houses nephritis from parenchymatous to interstitial form was observed in seven cows with the titers higher than 1 :1600; the nephritis was accompanied by granular adipose dystrophies and numerous infarcts in kidneys, the bacteriological picture was negative. RO - M:FES PMID- 6792767 LR - 820527 CU - 91 TT - Leptospirozy skotu v Jihoceskem kraji. EA - A SO - Vet Med (Praha) 1981 Jul;26(7):411-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82023546 AU - Liceras de Hidalgo J TI - [Leptospirosis in Tingo Maria, Huanuco Department, Peru. II. Study in wild animals] LA - Spa MH - Animal MH - Animals/*microbiology MH - Animals, Wild/*microbiology MH - English Abstract MH - Leptospirosis/epidemiology/*veterinary MH - Peru PT - JOURNAL ARTICLE DA - 811215 DP - 1981 Jul IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 47-55 CY - UNITED STATES IP - 1 VI - 91 JC - AGG EM - 8202 PMID- 6456737 CU - 92 TT - Leptospirosis en tingo Maria, Departamento de Huanuco, Peru. II. Estudio en animales silvestres. EA - A SO - Bol Oficina Sanit Panam 1981 Jul;91(1):47-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82063443 AU - Ellis WA AU - O'Brien JJ AU - Cassells J TI - Role of cattle in the maintenance of Leptospira interrogans serotype hardjo infection in Northern Ireland. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Carrier State MH - Cattle MH - Cattle Diseases/diagnosis/epidemiology/*transmission MH - Female MH - Kidney/microbiology MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/diagnosis/epidemiology/transmission/*veterinary MH - Male MH - Northern Ireland MH - Rodent Diseases/microbiology/transmission RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820120 DP - 1981 Jun 27 IS - 0042-4900 TA - Vet Rec PG - 555-7 SB - M CY - ENGLAND IP - 26 VI - 108 JC - XBS AA - Author EM - 8203 AB - Kidneys of cattle, mice and badgers were cultured for leptospires in an attempt to evaluate the relative importance of these species in the epidemiology of bovine leptospirosis caused by the Hebdomadis serogroup. Leptospires closely related to serotype hardjo were recovered from 57 (28.5 per cent) of 200 cattle examined but no evidence of infection was found in either badgers or mice, indicating that cattle act as the maintenance host for serotype hardjo. Many cattle were seronegative carriers. PMID- 7303438 CU - 91 SO - Vet Rec 1981 Jun 27;108(26):555-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 81233742 TI - Leptospirosis in man, British Isles, 1979-80. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Female MH - Great Britain MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Occupational Diseases/epidemiology PT - JOURNAL ARTICLE DA - 810915 DP - 1981 Jun 20 IS - 0267-0623 TA - Br Med J (Clin Res Ed) PG - 2066 SB - M CY - ENGLAND IP - 6281 VI - 282 JC - B4X EM - 8111 PMID- 6788204 CU - 91 NI - A SO - Br Med J (Clin Res Ed) 1981 Jun 20;282(6281):2066 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82121671 AU - Cinco M AU - Banfi E AU - Soranzo MR TI - Studies on the interaction between macrophages and leptospires. LA - Eng MH - Animal MH - Guinea Pigs MH - Leptospira/*immunology/ultrastructure MH - Leptospira interrogans/immunology MH - Macrophages/*immunology/ultrastructure MH - Microscopy, Electron MH - Phagocytosis MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 820412 DP - 1981 Jun IS - 0022-1287 TA - J Gen Microbiol PG - 409-13 SB - M CY - ENGLAND IP - Pt 2 VI - 124 JC - I87 AA - Author EM - 8206 AB - Guinea-pig macrophages exerted no bactericidal activity against either a virulent or a saprophytic strain of leptospira during a 120 min period of contact at 37 degrees C. However, the same macrophages exhibited weak phagocytic powers towards these two strains of leptospira over a similar period of time. PMID- 7328405 SO - J Gen Microbiol 1981 Jun;124(Pt 2):409-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 82006941 AU - Walker JF AU - Walsh J AU - Cronin CJ AU - Donohoe J AU - Carmody M AU - O'Dwyer WF TI - Acute renal failure in leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Female MH - Human MH - Kidney Failure, Acute/diagnosis/*etiology/therapy MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Pregnancy MH - Prognosis PT - JOURNAL ARTICLE DA - 811122 DP - 1981 Jun IS - 0021-1265 TA - Ir J Med Sci PG - 187-9 CY - IRELAND IP - 6 VI - 150 JC - GXB EM - 8201 PMID- 7275565 SO - Ir J Med Sci 1981 Jun;150(6):187-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 81259552 AU - Pashkow FJ AU - Calisher CH AU - Reller LB AU - Sulzer CR TI - Leptospirosis in a traveler from Honduras. LA - Eng MH - Adult MH - Case Report MH - Female MH - Honduras MH - Human MH - Serodiagnosis MH - *Travel MH - United States MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 811025 DP - 1981 Jun IS - 0035-760X TA - Colo Med PG - 210-2 CY - UNITED STATES IP - 6 VI - 78 JC - DI5 EM - 8112 PMID- 7261560 SO - Colo Med 1981 Jun;78(6):210-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82081170 AU - Schollum LM AU - Blackmore DK TI - The serological and cultural prevalence of leptospirosis in a sample of feral goats. LA - Eng MH - Animal MH - Animals, Wild MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Goats/*immunology/microbiology MH - Kidney/microbiology MH - Leptospira/*immunology/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - New Zealand MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820225 DP - 1981 Jun IS - 0048-0169 TA - N Z Vet J PG - 104-6 CY - NEW ZEALAND IP - 6 VI - 29 JC - OBZ EM - 8204 PMID- 6947159 CU - 91 SO - N Z Vet J 1981 Jun;29(6):104-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82041345 AU - Hathaway SC AU - Little TW AU - Finch SM AU - Stevens AE TI - Leptospiral infection in horses in England: a serological study. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - England MH - Horse Diseases/diagnosis/*epidemiology MH - Horses/*immunology MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/epidemiology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 811221 DP - 1981 May 2 IS - 0042-4900 TA - Vet Rec PG - 396-8 SB - M CY - ENGLAND IP - 18 VI - 108 JC - XBS EM - 8202 PMID- 7292908 CU - 91 SO - Vet Rec 1981 May 2;108(18):396-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 82072013 AU - Lin JR TI - [Pathogenic leptospiras isolated from various surface waters (author's transl)] LA - Chi MH - China MH - Leptospira/*isolation & purification MH - Seasons MH - Soil Microbiology MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 820222 DP - 1981 May TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 171-2 CY - CHINA IP - 3 VI - 15 JC - D74 EM - 8204 RO - M:MYA PMID- 7307831 LR - 820923 SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1981 May;15(3):171-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 82045669 AU - Cargill CF AU - Davos DE TI - Renal leptospirosis in vaccinated pigs. LA - Eng MH - Animal MH - Comparative Study MH - Kidney/pathology MH - Kidney Diseases/pathology/prevention & control/*veterinary MH - Leptospirosis/pathology/prevention & control/*veterinary MH - Male MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/pathology/*prevention & control MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 811215 DP - 1981 May IS - 0005-0423 TA - Aust Vet J PG - 236-8 SB - M CY - AUSTRALIA IP - 5 VI - 57 JC - 9IE EM - 8202 PMID- 7295241 SO - Aust Vet J 1981 May;57(5):236-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 81231191 AU - Skinhoj P AU - Hollinger FB AU - Hovind-Hougen K AU - Lous P TI - Infectious liver diseases in three groups of Copenhagen workers: correlation of hepatitis A infection to sewage exposure. LA - Eng MH - Adult MH - Aged MH - Denmark MH - Hepatitis A/*etiology/immunology MH - Hepatitis B/*etiology/immunology MH - Hepatitis B Surface Antigens/analysis MH - Human MH - Leptospirosis/immunology MH - Male MH - Middle Age MH - Occupational Diseases/*etiology MH - Radioimmunoassay MH - *Sewage MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Hepatitis B Surface Antigens) PT - JOURNAL ARTICLE DA - 810827 DP - 1981 May-Jun IS - 0003-9896 TA - Arch Environ Health PG - 139-43 SB - A SB - M CY - UNITED STATES IP - 3 VI - 36 JC - 6YO AA - Author EM - 8110 AB - Three groups of Copenhagen municipality male employees-77 sewer workers, 81 gardeners, and 79 clerks-matched for age and duration of employment, were studied for clinical and serological evidence of infection with viral hepatitis types A and B and pathogenic leptospires. "Antibody against hepatitis A virus" (anti-HAV) was found significantly more often among sewer workers (80.5%), than among gardeners (60.5%) or clerks (48.1%). The anti-HAV prevalence rates correlated with age rather than duration of employment. Of all the 11 cases of jaundice reported, only 3 cases (sewer workers) occurred while employed for the city. One case of the 11 resulted from leptospirosis. Anti-HAV was detected in the other 10 subjects and was assumed to be of etiological importance. Hepatitis B serological markers were similar in each group. It is concluded that exposure to metropolitan sewage provides a limited risk of enteric infections, such as hepatitis A, while the hepatitis B virus apparently is not successfully transmitted by this route. PMID- 7247461 CU - 91 SO - Arch Environ Health 1981 May-Jun;36(3):139-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81201939 AU - Edwards S AU - Nicholls MJ AU - Vallenjos F AU - Ibata G TI - Leptospirosis in cattle in Bolivia. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Bolivia MH - Cattle MH - Cattle Diseases/*diagnosis MH - Leptospira/classification MH - Leptospirosis/diagnosis/*veterinary MH - Serotyping MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 810723 DP - 1981 May IS - 0049-4747 TA - Trop Anim Health Prod PG - 117-8 SB - M CY - SCOTLAND IP - 2 VI - 13 JC - WG2 EM - 8109 PMID- 7233559 SO - Trop Anim Health Prod 1981 May;13(2):117-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81200085 AU - White FH AU - Sutherland GE AU - Raynor LE AU - Cottrell CR AU - Sulzer KR TI - Leptospira interrogans serovars hardjo and pomona: causes of infections in dairy cows and humans in Florida. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*etiology MH - Child MH - Dairying MH - Female MH - Florida MH - Human MH - Male MH - Occupational Diseases/etiology MH - Weil's Disease/*etiology/veterinary PT - JOURNAL ARTICLE DA - 810720 DP - 1981 May-Jun IS - 0033-3549 TA - Public Health Rep PG - 250-4 SB - A SB - M CY - UNITED STATES IP - 3 VI - 96 JC - QJA EM - 8109 PMID- 7232685 SO - Public Health Rep 1981 May-Jun;96(3):250-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 82006817 AU - Tatlock H TI - Rickettsia-like bacteria. LA - Eng MH - Bacteria/isolation & purification MH - Bacterial Infections/diagnosis MH - Bacteriology/*history MH - Communicable Diseases/diagnosis MH - History of Medicine, 20th Cent. MH - Human MH - Legionella/*isolation & purification MH - Leptospira/isolation & purification MH - Rickettsia/isolation & purification MH - United States PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 811118 DP - 1981 May-Jun IS - 0195-9417 TA - Infect Control PG - 254-5 SB - M SB - N CY - UNITED STATES IP - 3 VI - 2 JC - GTM EM - 8201 RO - M:MYA PMID- 7024165 LR - 820526 CU - 90 SO - Infect Control 1981 May-Jun;2(3):254-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82023537 AU - Liceras de Hidalgo J AU - Hidalgo R AU - Flores M TI - [Leptospirosis in Tingo Maria, Department of Huanuco, Peru. I. Study on man and domestic animals] LA - Spa MH - Abattoirs MH - Adult MH - Aged MH - Animal MH - Cat Diseases/epidemiology MH - Cats MH - Cattle MH - Cattle Diseases/epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - English Abstract MH - Goats MH - Guinea Pigs MH - Human MH - Leptospirosis/*epidemiology/*veterinary MH - Middle Age MH - Peru MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 811221 DP - 1981 May IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 430-8 CY - UNITED STATES IP - 5 VI - 90 JC - AGG EM - 8202 PMID- 6456728 CU - 92 TT - Leptospirosis en Tingo Maria, Departmentto de Huanuco, Peru. I. Estudio en el hombre y animales domesticos. EA - A SO - Bol Oficina Sanit Panam 1981 May;90(5):430-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 81258065 AU - Higgins R AU - Hoquet F AU - Marsolais G AU - Montpetit C AU - Elazhary Y AU - Morin M AU - Bois JM AU - Ethier R TI - [Diagnosis of septic abortion in dairy cows] LA - Fre MH - Abortion, Septic/diagnosis/etiology/*veterinary MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis/etiology MH - English Abstract MH - Female MH - Pregnancy MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 811025 DP - 1981 Apr IS - 0008-4050 TA - Can J Comp Med PG - 159-66 SB - M CY - CANADA IP - 2 VI - 45 JC - CI0 AA - Author EM - 8112 AB - During a two year period, March 1977 to April 1979, a total of 92 bovine abortions were studied. The cause of abortion was determined in 34.8% of the cases examined. Opportunistic bacteria, the most commonly diagnosed cause of abortion, accounted for 31.2% of the cases. Leptospirosis was associated with 28.1% of the abortions, infectious bovine rhinotracheitis and fungi in respectively 15.7%, bovine viral diarrhea in 6.2%. A congenital abnormality accounted for one case (3.1%). In 23 cases (25%), there was no definitive diagnosis, in spite of evidence of experience with pathogen or suggestive findings of pathology, but insufficient evidence to warrant diagnosis. No findings were recorded in 35.8% of the (possibly noninfectious) cases and in only four cases (4.4%), specimens were unsatisfactory for examination. PMID- 7260730 TT - Diagnostic des avortements infectieux chez les bovins laitiers. EA - A SO - Can J Comp Med 1981 Apr;45(2):159-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [9 medline neighbors] UI - 81218569 AU - Milner AR AU - Wilks CR AU - Spratt DM AU - Presidente PJ TI - The prevalence of anti-leptospiral agglutinins in sera of wildlife in southeastern Australia. LA - Eng MH - Agglutination Tests/veterinary MH - Agglutinins/*analysis MH - Animal MH - Animals/*immunology MH - Animals, Wild/*immunology MH - Antibodies, Bacterial/*analysis MH - Australia MH - Leptospira/*immunology MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810810 DP - 1981 Apr IS - 0090-3558 TA - J Wildl Dis PG - 197-202 SB - M CY - UNITED STATES IP - 2 VI - 17 JC - KEM AA - Author EM - 8110 AB - Anti-leptospiral agglutinins were found in the serum from 18 (7 species) of 419 (25 species) animals sampled from various areas of southeastern Australia. Positive serologic reactions were observed in 5 of 25 (20%) brush-tailed possum (Trichosurus vulpecula), 1 of 26 (3.8%) tammar wallaby (Macropus eugenii), 2 of 12 (16.7%) swamp wallaby (Wallabia bicolor), 1 of 3 (33.3%) koala (Phascolarctos cinereus), 3 of 41 (7.3%) common wombat (Vombatus ursinus), 2 of 100 (2%) bush rat (Rattus fuscipes) and 4 of 12 (25%) rusa deer (Cervus timorensis). The majority (55.5%) of serologic reactions were to serovar hardjo. No serologic reactions were observed in samples from echidna (Tachyglossus aculeatus), brown antechinus (Antechinus stuartii), swainson's antechinus (Antechinus swaisonsii), long-nosed bandicoot (Perameles nasuta), brown bandicoot(Isoodon obesulus), common ringtail (Pseudocheirus peregrinus), greater glider (Schoinobates volans), eastern grey kangaroo (Macropus giganteus), red-necked wallaby (Macropus rufogriseus), rabbit (Oryctolagus cuniculus), water rat (Hydromys chrysogaster), black rat (Rattus rattus), eastern swamp rat (Rattus lutreolus), broad-toothed rat (Mastacomys fuscus), fox (Vulpes vulpes), sambar deer (Cervus unicolor), hog deer (Axis porcinus) and fallow deer (Dama dama). PMID- 7241704 CU - 91 SO - J Wildl Dis 1981 Apr;17(2):197-202 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [94 medline neighbors] UI - 81207918 AU - Williams CS AU - Siddique IH AU - Sapp WJ TI - Studies on the kidneys of pregnant hamsters infected with Leptospira canicola. LA - Eng MH - Animal MH - Female MH - Hamsters MH - Kidney/microbiology/*ultrastructure MH - Leptospira canicola MH - Leptospirosis/microbiology/*pathology MH - Microscopy, Electron MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology/*pathology MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 810820 DP - 1981 Apr IS - 0007-1021 TA - Br J Exp Pathol PG - 165-71 SB - M CY - ENGLAND IP - 2 VI - 62 JC - AWW AA - Author EM - 8110 AB - An electron microscopic study on the histopathological changes in the kidneys of pregnant hamsters resulting from infection with Leptospira canicola was undertaken. The experiment revealed damage to the glomeruli as well as the tubules. The severity of these lesions increased with the progress of the disease and examination of kidney sections showed leptospires in the tissue. It is suggested that the stress of pregnancy has some influence on the severity of the lesions seen in this disease. PMID- 7236498 SO - Br J Exp Pathol 1981 Apr;62(2):165-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 81163561 AU - Schmitz JA AU - Coles BM AU - Shires GM TI - Fatal hemolytic disease in sheep attributed to Leptospira interrogans serotype hardjo infection. LA - Eng MH - Animal MH - Animals, Newborn MH - Antibodies, Bacterial/analysis MH - Erythroblastosis, Fetal/immunology/pathology/*veterinary MH - Female MH - Leptospirosis/immunology/pathology/*veterinary MH - Pregnancy MH - Sheep MH - Sheep Diseases/*immunology/pathology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810625 DP - 1981 Apr IS - 0010-8901 TA - Cornell Vet PG - 175-82 SB - M CY - UNITED STATES IP - 2 VI - 71 JC - DRI AA - Author EM - 8108 AB - An outbreak of acute hemolytic disease in a large flock of sheep resulted in a mortality of approximately 5% in lambs. A diagnosis of Leptospira interrogans serotype hardjo infection was established on the basis of the presence of leptospires in the urine of one lamb, serologic findings in a guinea pig inoculated with this urine, L. hardjo titers in lambs, and pathologic findings. Prominent necropsy findings included severe icterus, thin watery blood, dark red to black kidneys and severe hemoglobinuria. PMID- 7194169 CU - 91 SO - Cornell Vet 1981 Apr;71(2):175-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81246091 AU - Mackintosh CG AU - Marshall RB TI - Cross-protection between hardjo and balcanica [letter] LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Hamsters MH - Leptospirosis/prevention & control/*veterinary MH - Rodent Diseases/*prevention & control RN - 0 (Bacterial Vaccines) PT - LETTER DA - 810925 DP - 1981 Apr IS - 0048-0169 TA - N Z Vet J PG - 64 CY - NEW ZEALAND IP - 4 VI - 29 JC - OBZ EM - 8111 PMID- 6942346 CU - 91 SO - N Z Vet J 1981 Apr;29(4):64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81246275 AU - Fuzi M AU - Csukas Z TI - [Antibiotic sensitivity of pathogenic Leptospirae] LA - Hun MH - Antibiotics/*pharmacology MH - Leptospira/*drug effects/pathogenicity MH - Microbial Sensitivity Tests RN - 0 (Antibiotics) PT - JOURNAL ARTICLE DA - 810915 DP - 1981 Mar 22 IS - 0030-6002 TA - Orv Hetil PG - 691-3 CY - HUNGARY IP - 12 VI - 122 JC - OL8 EM - 8111 PMID- 7254802 CU - 91 TT - Pathogen leptospirak antibiotikum erzekenysege. SO - Orv Hetil 1981 Mar 22;122(12):691-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 81250929 AU - Hathaway SC AU - Little TW TI - Prevalence and clinical significance of leptospiral antibodies in pigs in England. LA - Eng MH - Abortion, Veterinary/immunology MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial/analysis MH - Comparative Study MH - England MH - Female MH - Leptospira/*immunology MH - Male MH - Pregnancy MH - Swine/*immunology MH - Swine Diseases/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 810915 DP - 1981 Mar 14 IS - 0042-4900 TA - Vet Rec PG - 224-8 SB - M CY - ENGLAND IP - 11 VI - 108 JC - XBS AA - Author EM - 8111 AB - The results of leptospiral serology conducted on porcine sera at the Central Veterinary Laboratory, Weybridge from 1971 to 1978 were collated and analysed. Sera were available from diagnostic submissions (1622) and from pigs intended fro export (5031). A random sample of 792 sera from 34 herds was also examined. The overall prevalence of infection was low. Copenhageni titres were present in 7.9 per cent of diagnostic submissions and a statistical association with jaundice was shown in piglets and adults. The introduction of Australis serogroup antigens in 1978 revealed the serological prevalences to lora and bratislava to be in excess of 20 per cent. However the causative serotype has yet to be identified. Leptospiral infection was not a significant cause of abortion in pigs. The pattern of leptospiral infection in pigs in England is considerably different from that occurring in other countries and it is considered that free-living maintenance host populations constitute the primary sources of infection. PMID- 7257119 CU - 91 SO - Vet Rec 1981 Mar 14;108(11):224-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 81091744 AU - Farkas PS AU - Knapp AB AU - Lieberman H AU - Guttman I AU - Mayan S AU - Bloom AA TI - Markedly elevated creatinine phosphokinase, cotton wool spots, and pericarditis in a patient with leptospirosis. LA - Eng MH - Adult MH - Case Report MH - Creatine Kinase/blood MH - Hepatitis/etiology MH - Human MH - Male MH - Myositis/etiology MH - Pericarditis/etiology MH - Support, U.S. Gov't, P.H.S. MH - Vision Disorders/etiology MH - Weil's Disease/*diagnosis RN - EC 2.7.3.2 (Creatine Kinase) PT - JOURNAL ARTICLE ID - AM 07218/AM/NIADDK DA - 810324 DP - 1981 Mar IS - 0016-5085 TA - Gastroenterology PG - 587-9 SB - A SB - M CY - UNITED STATES IP - 3 VI - 80 JC - FH3 AA - Author EM - 8105 AB - We are reporting a patient with acute leptospirosis whose creatinine phosphokinase was markedly elevated secondary to an associated myositis. In patients presenting with acute hepatitis, an elevated creatinine phosphokinase should suggest the diagnosis of leptospirosis. Our patient's course of illness was made unusual by the appearance of cotton wool spots, previously unreported in leptospirosis as well as by pericarditis in the absence of uremia. This illustrates our ever widening recognition of the clinical manifestations of leptospirosis. PMID- 7450450 CU - 96 SO - Gastroenterology 1981 Mar;80(3):587-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 82029685 AU - Deas W TI - Non-brucella abortion in cattle. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Bovine Virus Diarrhea-Mucosal Disease/complications MH - Cattle MH - Cattle Diseases/*etiology MH - Corynebacterium Infections/complications/veterinary MH - Female MH - Infectious Bovine Rhinotracheitis/complications MH - Leptospirosis/complications/veterinary MH - Mycoses/complications/veterinary MH - Pregnancy MH - Salmonella Infections, Animal/complications PT - JOURNAL ARTICLE DA - 811221 DP - 1981 Mar TA - In Pract PG - 14-9 SB - M CY - ENGLAND IP - 2 VI - 3 JC - GPF EM - 8202 PMID- 7287192 CU - 90 SO - In Pract 1981 Mar;3(2):14-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82010380 AU - Wilson D AU - Wetson R TI - Leptospirosis-a diagnostic problem and an industrial hazard. LA - Eng MH - Adult MH - Agricultural Workers' Diseases/*transmission MH - Case Report MH - Human MH - Leptospirosis/diagnosis/*transmission MH - Male MH - Weil's Disease/diagnosis/transmission PT - JOURNAL ARTICLE DA - 811118 DP - 1981 Mar IS - 0035-8797 TA - J R Coll Gen Pract PG - 165-7 CY - ENGLAND IP - 224 VI - 31 JC - JV9 EM - 8201 PMID- 7277295 SO - J R Coll Gen Pract 1981 Mar;31(224):165-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 81277985 AU - Torres J AU - Ueno K AU - Yanagawa R TI - Specificity of leptospiricidal activity test mediated by antiserum and complement. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/immunology MH - *Blood Bactericidal Activity MH - Complement MH - Cross Reactions MH - *Immunologic Techniques MH - Leptospira/classification/*immunology MH - Leptospira interrogans/classification/*immunology MH - Serotyping MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 811025 DP - 1981 Mar IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 124-32 SB - M CY - GERMANY, WEST IP - 1 VI - 249 JC - Y5P AA - Author EM - 8112 AB - A leptospiricidal activity test mediated by immune serum plus guinea pig complement using 11 serovars of leptospiras belonging to 3 serogroups, Icterohaemorrhagiae, Pomona and Mini, indicated that the reaction was generally serogroup-specific. The immune serum from which the homologous or heterologous agglutinin was absorbed was then examined with the result that the anti-L. icterohaemorrhagiae and anti- L. sarmin antisera which absorbed with L. icterohaemorrhagiae and L. sarmin respectively did not agglutinate, but instead destroyed their homologous leptospiras in conjunction with complement. Many of the antisera which absorbed with the heterologous serovars did not agglutinate, but instead destroyed their respective heterologous strain. These findings indicate that the leptospiricidal activity test is more sensitive and more cross reactive than agglutination. PMID- 7023117 CU - 91 SO - Zentralbl Bakteriol [A] 1981 Mar;249(1):124-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 81248479 AU - Spencer AJ AU - Wright NG TI - Chronic interstitial nephritis in the dog: an immunofluorescence and elution study. LA - Eng MH - Animal MH - Antibodies, Bacterial/isolation & purification MH - Chronic Disease MH - Comparative Study MH - Dog Diseases/*immunology MH - Dogs MH - Fluorescent Antibody Technique MH - Kidney Cortex/*analysis MH - Leptospira interrogans/immunology MH - Nephritis, Interstitial/immunology/*veterinary MH - Proteins/*isolation & purification MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810925 DP - 1981 Mar IS - 0034-5288 TA - Res Vet Sci PG - 226-32 SB - M CY - ENGLAND IP - 2 VI - 30 JC - R7D EM - 8111 PMID- 7020015 CU - 91 SO - Res Vet Sci 1981 Mar;30(2):226-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 81246082 AU - Flint SH AU - Liardet DM TI - Leptospira interrogans serovar hardjo vaccination against Leptospira interrogans serovar balcanica infection [letter] LA - Eng MH - Animal MH - Bacterial Vaccines/*immunology MH - Cross Reactions MH - Hamsters MH - Leptospira interrogans/*immunology MH - Weil's Disease/prevention & control/*veterinary RN - 0 (Bacterial Vaccines) PT - LETTER DA - 810925 DP - 1981 Mar IS - 0048-0169 TA - N Z Vet J PG - 38 CY - NEW ZEALAND IP - 3 VI - 29 JC - OBZ EM - 8111 PMID- 6942338 CU - 91 SO - N Z Vet J 1981 Mar;29(3):38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 81277986 AU - Shimono E AU - Yanagawa R TI - Unstable antigenic variation of leptospiras. LA - Eng MH - Agglutination Tests MH - Antigens, Bacterial/*immunology MH - Epitopes MH - Leptospira interrogans/genetics/*immunology MH - Mutation MH - *Variation (Genetics) RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 811025 DP - 1981 Mar IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 133-41 SB - M CY - GERMANY, WEST IP - 1 VI - 249 JC - Y5P AA - Author EM - 8112 AB - The antigenic variants which were found in leptospiras, Leptospira interrogans serovar copenhageni Shibaura grown in a liquid medium containing a homologous antiserum were found to be unstable. The unstable variants showed decreased agglutinability against the homologous antiserum. The decreased agglutinability of the unstable variants reverted to the parent's level of agglutinability after 1 or 2 passages through the normal serum medium. The unstable variants differed antigenically from the parent in the agglutinin-absorption test; however, the agglutinin-absorption test was found to be inadequate for showing the antigenic difference between the parent and the unstable variants because their difference was diminished when the agglutinin-absorbed antigen was increased. The application of Laurell rocket immunoelectrophoresis (LRI) to the SDS-extracted antigens revealed the distinct difference between the parent and the unstable variants. Other findings presented herein indicated the difference between the antigens of the parent and the unstable variants to be one of quantity. The magnitude of the quantitative difference between the antigens could be modified by the medium containing various concentrations of the homologous antiserum. The clones of the unstable variant showed antigenic characteristics which were similar to the original unstable variant. PMID- 6168141 CU - 95 SO - Zentralbl Bakteriol [A] 1981 Mar;249(1):133-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81212591 AU - Banfi E AU - Cinco M AU - Dri P TI - Catalase activity among leptospires. LA - Eng MH - Animal MH - Catalase/*metabolism MH - Comparative Study MH - Leptospira/*enzymology MH - Species Specificity MH - Water Microbiology RN - EC 1.11.1.6 (Catalase) PT - JOURNAL ARTICLE DA - 810810 DP - 1981 Feb 15 IS - 0014-4754 TA - Experientia PG - 147-8 SB - M CY - SWITZERLAND IP - 2 VI - 37 JC - EQZ EM - 8110 PMID- 7238738 SO - Experientia 1981 Feb 15;37(2):147-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82071890 TI - [Observation of clinical therapeutic effect of ethyl 4(5)- imidazolecarboxylate in 474 cases of leptospirosis (author's transl)] LA - Chi MH - Adolescence MH - Adult MH - Aged MH - Antibiotics/*therapeutic use MH - Child MH - Child, Preschool MH - Female MH - Human MH - Imidazoles/adverse effects/*therapeutic use MH - Leptospirosis/*drug therapy MH - Male MH - Middle Age RN - 0 (Antibiotics) RN - 0 (Imidazoles) RN - 23785-21-9 (C 751) PT - JOURNAL ARTICLE DA - 820212 DP - 1981 Feb IS - 0578-1426 TA - Chung Hua Nei Ko Tsa Chih PG - 99-101 CY - CHINA IP - 2 VI - 20 JC - D7V EM - 8204 PMID- 7307727 CU - 96 NI - A SO - Chung Hua Nei Ko Tsa Chih 1981 Feb;20(2):99-101 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82071889 AU - Zhong SC TI - [A discussion of the early clinical diagnosis of leptospirosis--a clinical analysis of 570 cases (author's transl)] LA - Chi MH - Adolescence MH - Adult MH - Child MH - Diagnostic Errors MH - Female MH - Human MH - Leptospirosis/*diagnosis/drug therapy MH - Male MH - Middle Age MH - Penicillins/therapeutic use RN - 0 (Penicillins) PT - JOURNAL ARTICLE DA - 820212 DP - 1981 Feb IS - 0578-1426 TA - Chung Hua Nei Ko Tsa Chih PG - 95-8 CY - CHINA IP - 2 VI - 20 JC - D7V EM - 8204 PMID- 7307726 CU - 96 SO - Chung Hua Nei Ko Tsa Chih 1981 Feb;20(2):95-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 81179753 AU - Hovind-Hougen K AU - Hoybe G TI - Urinary excretion of an unidentified treponeme in a case of leptospirosis. LA - Eng MH - Adolescence MH - Case Report MH - Human MH - Leptospira/classification/isolation & purification/ultrastructure MH - Leptospirosis/*microbiology MH - Male MH - Microscopy, Electron MH - Treponema/classification/*isolation & purification/ultrastructure MH - Urine/*microbiology PT - JOURNAL ARTICLE DA - 810625 DP - 1981 Feb IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 532-40 SB - M CY - GERMANY, WEST IP - 4 VI - 248 JC - Y5P AA - Author EM - 8108 AB - Two kinds of spirochetes were observed by dark-field microscopy in the urine of a leptospirosis patient on day 26 after the onset of the disease. The spirochetes were identified as treponemes and leptospires. A classification of the treponemes on basis of their morphology was attempted by means of electron microscopy with no conclusive result. Cultivation of the spirochetes was unsuccessful. Sera obtained prior to, during and after the excretion of spirochetes were tested for antibodies in routine serology tests for leptospirosis and syphilis. The diagnosis leptospirosis was confirmed by a rise and subsequent fall in antibody titres. The sera were nonreactive in syphilis serology tests, but showed a weak fluorescence in a fluorescent treponemal antibody absorption (FTA-ABS) test when Treponema calligyrum was used as antigen. It could not be determined whether this reaction was due to antibodies raised in response to antigens of the excreted treponemes. RO - M:FES PMID- 7223134 LR - 810730 SO - Zentralbl Bakteriol [A] 1981 Feb;248(4):532-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 82071878 AU - Kao XS TI - [Clinical observation of treatment of 281 cases of leptospirosis with methimidol hydrochloride (author's transl)] LA - Chi MH - Adolescence MH - Adult MH - Anti-Infective Agents/*therapeutic use MH - Child MH - Female MH - Human MH - Imidazoles/adverse effects/*therapeutic use MH - Leptospirosis/*drug therapy MH - Male MH - Middle Age MH - Penicillins/therapeutic use RN - 0 (Anti-Infective Agents) RN - 0 (Imidazoles) RN - 0 (Penicillins) RN - 1615-15-2 (methimidol) PT - JOURNAL ARTICLE DA - 820212 DP - 1981 Feb IS - 0578-1426 TA - Chung Hua Nei Ko Tsa Chih PG - 102-5 CY - CHINA IP - 2 VI - 20 JC - D7V EM - 8204 RO - M:DLJ PMID- 7053113 LR - 840806 CU - 96 SO - Chung Hua Nei Ko Tsa Chih 1981 Feb;20(2):102-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 81179755 AU - Ueno K AU - Yanagawa R TI - Antigenic variants of leptospiras selected by antiserum-complement mediated-killing. LA - Eng MH - Animal MH - Antigens, Bacterial/*genetics/immunology MH - Complement/immunology MH - Guinea Pigs/immunology MH - Hamsters MH - Immune Sera MH - *Immunologic Techniques MH - Leptospira/*genetics/immunology/pathogenicity MH - Male MH - Rabbits/immunology MH - Species Specificity MH - *Variation (Genetics) MH - Virulence RN - 0 (Antigens, Bacterial) RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 810625 DP - 1981 Feb IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 548-57 SB - M CY - GERMANY, WEST IP - 4 VI - 248 JC - Y5P AA - Author EM - 8108 AB - The presence of antigenic variants of leptospiras was confirmed by the leptospiricidal reaction mediated by the antiserum plus complement. More than 99% of the organisms of virulent L. copenhageni Shibaura were destroyed microscopically after treatment with the anti-L. copenhageni Shibaura antiserum (1: 2000) plus guinea pig complement (1: 20). The leptospiras which survived treatment with the antiserum plus complement produced colonies on the solid serum medium at a rate of 0.09%. Eighty- seven percent of the survivors were found to be antigenic variants. The antigenicity of these variants reversed to that of the parent after 3-- 5 passages in the liquid normal serum medium. RO - M:FES PMID- 7013365 LR - 810730 CU - 91 SO - Zentralbl Bakteriol [A] 1981 Feb;248(4):548-57 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 81118157 AU - Jones PW AU - Rennison LM AU - Matthews PR AU - Collins P AU - Brown A TI - The occurrence and significance to animal health of Leptospira, Mycobacterium, Escherichia coli, Brucella abortus and Bacillus anthracis in sewage and sewage sludges. LA - Eng MH - Animal MH - Animal Diseases/prevention & control MH - Animals, Domestic MH - Bacillus anthracis/*isolation & purification MH - Bacteriological Techniques MH - Brucella abortus/*isolation & purification MH - Escherichia coli/*isolation & purification MH - Leptospira/*isolation & purification MH - Mycobacterium/*isolation & purification MH - Sewage/*analysis MH - Support, Non-U.S. Gov't MH - Water Microbiology PT - JOURNAL ARTICLE DA - 810413 DP - 1981 Feb IS - 0022-1724 TA - J Hyg (Lond) PG - 129-37 SB - M CY - ENGLAND IP - 1 VI - 86 JC - IEF AA - Author EM - 8106 AB - Samples of sewage, sewage sludge and sewage effluent from one or more of four sewage treatment plants were examined for the presence of Leptospira, Mycobacterium, Escherichia coli, Brucella abortus and Bacillus anthracis. Brucella abortus and Bacillus anthracis were not isolated. Eleven strains of E. coli potentially enteropathogenic for calves or piglets, eight pathogenic strains of Mycobacterium and one patho;genic Leptospira strain were isolated from 101, 189 and 189 samples respectively. Sewage sludge is no;t considered to play a major part in the epidemiology of disease caused by these organisms. PMID- 6780619 CU - 91 SO - J Hyg (Lond) 1981 Feb;86(1):129-37 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81160356 AU - Liceras de Hidalgo J AU - Mejia E TI - [Leptospirosis in Iquitos, Department of Loreto, Peru] LA - Spa MH - Adult MH - Animal MH - Cattle MH - Disease Reservoirs MH - Guinea Pigs MH - Human MH - Kidney MH - Leptospira/immunology MH - Leptospirosis/immunology/*microbiology MH - Peru MH - Rats MH - Swine MH - Tissue Culture PT - JOURNAL ARTICLE DA - 810623 DP - 1981 Feb IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 152-9 CY - UNITED STATES IP - 2 VI - 90 JC - AGG EM - 8108 PMID- 6452147 CU - 92 TT - Leptospirosis en iquitos, departamento de Loreto, Peru. SO - Bol Oficina Sanit Panam 1981 Feb;90(2):152-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 81119778 AU - Marshall RB AU - Wilton BE AU - Robinson AJ TI - Identification of Leptospira serovars by restriction-endonuclease analysis. LA - Eng MH - DNA Restriction Enzymes/*analysis MH - Leptospira/*classification/enzymology RN - EC 3.1.21 (DNA Restriction Enzymes) PT - JOURNAL ARTICLE DA - 810424 DP - 1981 Feb IS - 0022-2615 TA - J Med Microbiol PG - 163-6 SB - M CY - ENGLAND IP - 1 VI - 14 JC - J2N AA - Author EM - 8106 AB - Strains of Leptospira interrogans were examined by restriction- endonuclease analysis. Serovars hardjo and balcanica gave patterns that differed from each other, and from those of other members of the Hebdomadis serogroup and members of other serogroups. The method should be useful for the identification of leptospires and might throw light on problems of their classification. PMID- 6257907 CU - 93 SO - J Med Microbiol 1981 Feb;14(1):163-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81152061 AU - Ortega Suarez R AU - Banos Gallardo M AU - Alonso Alvarez M AU - Marin Iranzo R AU - Alvarez Grande J AU - Faedo Presa I AU - Rodrigo Saez L AU - Prendes Pelaez P AU - Alvarez Fernandez M AU - Fuentes Martin E TI - [Liver and kidney disorders in icterohemorrhagic leptospirosis. Apropos of 6 cases] LA - Spa MH - Adult MH - Aged MH - Disease Outbreaks MH - English Abstract MH - Human MH - Kidney/pathology MH - Kidney Failure, Acute/*etiology MH - Liver/pathology MH - Liver Diseases/*etiology MH - Male MH - Middle Age MH - Nephritis, Interstitial/etiology MH - Spain MH - Weil's Disease/*complications/epidemiology PT - JOURNAL ARTICLE DA - 810528 DP - 1981 Jan 31 IS - 0014-2565 TA - Rev Clin Esp PG - 103-8 CY - SPAIN IP - 2 VI - 160 JC - RNL EM - 8107 PMID- 7209057 CU - 88 TT - Afectacion renal y hepatica de la leptospirosis icterohemorragica. A proposito de seis casos. EA - A SO - Rev Clin Esp 1981 Jan 31;160(2):103-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 81103481 AU - Maze SS AU - Kirsch RE TI - Leptospirosis experience at Groote Schuur Hospital, 1969-1979. LA - Eng MH - Adult MH - Agglutination Tests MH - Case Report MH - Diagnosis, Differential MH - Female MH - Human MH - Leptospira canicola/classification MH - Leptospira interrogans/classification MH - Leptospirosis/*diagnosis/microbiology MH - Male MH - Middle Age MH - Serotyping MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE DA - 810327 DP - 1981 Jan 10 IS - 0038-2469 TA - S Afr Med J PG - 33-6 SB - M CY - SOUTH AFRICA IP - 2 VI - 59 JC - U4R AA - Author EM - 8105 AB - The diagnosis of leptospirosis requires a high index of suspicion and a knowledge of the wide variety of syndromes with which these patients present. The clinical and laboratory features of 14 patients with leptospirosis seen at Groote Schuur Hospital, Cape Town, between 1969 and 1979 are described. PMID- 7455830 SO - S Afr Med J 1981 Jan 10;59(2):33-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81117679 AU - Wood J AU - Johnson RC AU - Palin K TI - Surface colonies of Leptospira interrogans. LA - Eng MH - Antigens, Bacterial/analysis MH - Culture Media MH - Leptospira/cytology MH - Leptospira interrogans/*growth & development/pathogenicity MH - Movement RN - 0 (Antigens, Bacterial) RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 810413 DP - 1981 Jan IS - 0095-1137 TA - J Clin Microbiol PG - 102-5 SB - M CY - UNITED STATES IP - 1 VI - 13 JC - HSH AA - Author EM - 8106 AB - Observations of colonial growth of Leptospira interrogans serovar pomona, BJ, on soft-agar (1% agar) plates revealed the presence of both surface and subsurface colonies. The organisms from both types of colonies appeared to be similar in motility, morphology, antigenic composition, and pathogenicity. Passage in vivo tended to produce a higher incidence of surface colonies, whereas passage in vitro tended to produce a higher incidence of subsurface colonies, suggesting the importance of environmental factors in determining the type of colony produced. PMID- 7462407 CU - 91 SO - J Clin Microbiol 1981 Jan;13(1):102-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [77 medline neighbors] UI - 82225407 AU - Belchev L AU - Khristov T AU - Chifudov D TI - [Metrifonate-induced congenital tremor in piglets] LA - Bul MH - Animal MH - Cerebellum/pathology MH - English Abstract MH - Female MH - Pregnancy MH - *Prenatal Exposure Delayed Effects MH - Swine MH - Swine Diseases/*chemically induced/congenital MH - Tremor/chemically induced/congenital/*veterinary MH - Trichlorfon/*adverse effects RN - 52-68-6 (Trichlorfon) PT - JOURNAL ARTICLE DA - 820807 DP - 1981 IS - 0506-8215 TA - Vet Med Nauki PG - 77-82 SB - M CY - BULGARIA IP - 7 VI - 18 JC - XCE AA - Author EM - 8210 AB - Congenital tremor was experimentally induced in pigs. Eight sows of the Comborough breed that had farrowed for the first time were used, having a good body condition and a liveweight of 115 to 120 kg. Other 96 sows of the same breed and body weight were used as controls. The test animals were given metrifonate orally in the prescribed therapeutic and prophylactic doses (50 mg/kg) four times during pregnancy. Both test and control sows were fed a standard mixture No 16 during pregnancy, and were vaccinated against swine fever, leptospirosis, Aujeszky's disease, and erysipelas. Congenital tremor was manifested in 42 out of 78 offsprings. The following conclusions were drawn: 1. The induced congenital tremor was manifested morphologically by varying hypoplasia of the cerebellum. 2. The use of organic phospohrous compounds for therapeutic and prophylactic purposes should be reduced during pregnancy. 3. The induced congenital tremor in pigs clinically and morphologically similar to the spontaneous congenital tremor in these animals described previously by the same authors. PMID- 7344282 TT - Eksperimentalno vuzproizvezhdane na kongenitalen tremor pri praseta s metrofonat. EA - A SO - Vet Med Nauki 1981;18(7):77-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 82214577 AU - Cox PJ AU - Twigg GI TI - Observations on kidney damage in hamsters following a non- icterohaemorrhagic form of disease resulting from infection by Leptospira interrogans serotype icterohaemorrhagiae. LA - Eng MH - Animal MH - Antigens, Bacterial/analysis MH - Female MH - Hamsters MH - Kidney/*pathology MH - Leptospira interrogans/immunology MH - Male MH - Support, Non-U.S. Gov't MH - Weil's Disease/immunology/*pathology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 820826 DP - 1981 Jan IS - 0021-9975 TA - J Comp Pathol PG - 153-7 SB - M CY - ENGLAND IP - 1 VI - 91 JC - HVB EM - 8210 PMID- 7343572 CU - 91 SO - J Comp Pathol 1981 Jan;91(1):153-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [56 medline neighbors] UI - 82173293 AU - Oravec C AU - Kmety E TI - Experimental biotherapy by leptospiral infection. IX. Quantitative titration of the tumoricidal effect of leptospiral exoproducts by means of 51Cr-labeled target cells of mouse ascites tumors. LA - Eng MH - Animal MH - Chromium Radioisotopes/*diagnostic use MH - *Leptospira MH - Lymphoma/*therapy MH - Mice MH - Mice, Inbred DBA MH - Neoplasms, Experimental/therapy RN - 0 (Chromium Radioisotopes) PT - JOURNAL ARTICLE DA - 820624 DP - 1981 IS - 0028-2685 TA - Neoplasma PG - 705-8 SB - M CY - CZECHOSLOVAKIA IP - 6 VI - 28 JC - NVO EM - 8208 PMID- 7339498 CU - 92 SO - Neoplasma 1981;28(6):705-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82108695 AU - Brown GW AU - Madasamy M AU - Bernthal P AU - Groves MG TI - Leptospirosis in Nepal. LA - Eng MH - Adult MH - Antibodies, Bacterial/analysis MH - Case Report MH - Human MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Nepal MH - Support, Non-U.S. Gov't MH - Support, U.S. Gov't, Non-P.H.S. RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820313 DP - 1981 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 572-3 SB - M CY - ENGLAND IP - 4 VI - 75 JC - WBU AA - Author EM - 8205 AB - We present here a case report of a suspected leptospiral infection in a Nepali soldier, and the results of a serological survey of 188 residents of Eastern Nepal that indicate the infection may be common there. This is the first report of leptospirosis in Nepal although it is known to affect man and animals in most of the temperate and tropical regions of the world, and apparently occurs widely in India (Das Gupta, 1938; Khanna & Iyer, 1971). PMID- 7324133 CU - 91 SO - Trans R Soc Trop Med Hyg 1981;75(4):572-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 82080188 AU - Tsuji M AU - Kawaoka Y AU - Naiki M AU - Yanagawa R TI - Isolation of antigenically active components from leptospiral serovar- specific lipopolysaccharide antigen by alkaline treatment. LA - Eng MH - Bacterial Proteins/analysis MH - Carbohydrates/analysis/immunology MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Lipids/analysis MH - Lipopolysaccharides/analysis/*immunology MH - Sodium Hydroxide MH - Support, Non-U.S. Gov't RN - 0 (Bacterial Proteins) RN - 0 (Lipopolysaccharides) RN - 1310-73-2 (Sodium Hydroxide) PT - JOURNAL ARTICLE DA - 820212 DP - 1981 TA - Microbiol Immunol PG - 949-57 SB - M CY - JAPAN IP - 9 VI - 25 JC - MX7 AA - Author EM - 8204 AB - The serovar-specific main antigen (TM antigen) of Leptospira interrogans serovar canicola, which as lipopolysaccharide properties, was treated with 0.1 N sodium hydroxide. This treatment degraded the antigen into two major antigenic components, one of high and one of low molecular weight. The component with the lower molecular weight (approximately 4,000 daltons) consisted mainly of carbohydrates, having lost almost all of the fatty acid and protein components of the original antigen. Although the substance lacked immunoprecipitable activity, it continued to show serovar-specific inhibitory potency in a radioimmunoassay system as well as in a microscopic immunoagglutination reaction of the organisms. The antigenic activity of the compound was also reduced by periodate oxidation as was that of the TM antigen. A component with the same chemical and physicochemical properties was also produced by alkaline treatment from a different serotype TM antigen (serovar kremastos Kyoto), but it showed no antigenic activity. PMID- 7311890 CU - 91 SO - Microbiol Immunol 1981;25(9):949-57 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 82034952 AU - Falisevac J AU - Schonwald S AU - Barsic BU AU - Makek N TI - [Epidemiological and clinical observations of leptospiroses over a 33- year period (author's transl)] LA - Scr MH - Adolescence MH - Adult MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Infant MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Yugoslavia PT - JOURNAL ARTICLE DA - 811215 DP - 1981 Jan IS - 0024-3477 TA - Lijec Vjesn PG - 1-4 CY - YUGOSLAVIA IP - 1 VI - 103 JC - L6C EM - 8202 PMID- 7289727 CU - 88 TT - Epidemioloska i klinicka zapazanja o leptospirozama tijekom 33 godine. EA - A SO - Lijec Vjesn 1981 Jan;103(1):1-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 81242566 AU - Thiermann AB TI - The Norway rat as a selective chronic carrier of Leptospira icterohaemorrhagiae. LA - Eng MH - Animal MH - Carrier State/microbiology/*veterinary MH - Leptospira/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Rats/*microbiology MH - Rodent Diseases/*microbiology PT - JOURNAL ARTICLE DA - 810922 DP - 1981 Jan IS - 0090-3558 TA - J Wildl Dis PG - 39-43 SB - M CY - UNITED STATES IP - 1 VI - 17 JC - KEM AA - Author EM - 8111 AB - Laboratory raised wild Norway rat males (Rattus norvegicus) were injected with leptospires of two serovars: icterohaemorrhagiae and grippotyphosa. The development of a carrier state was monitored serologically, culturally and histologically. Rats infected with icterohaemorrhagiae developed rapidly into a chronic carrier state and shed leptospires in the urine for the duration of the experiment (220 days). At the time of necropsy, histopathologic studies showed evidence of leptospiral infections in the lumen of proximal convoluted tubules of some kidneys. Rats infected with grippotyphosa shed organisms for 40 days after inoculation; thereafter, they apparently cleared the infection. No organisms were detected histologically nor by culture at the end of the experiment (220 days). There appears to be a specific host-parasite relationship in the Norway rat towards becoming chronic carriers when infected with serotype icterohaemorrhagiae but not with grippotyphosa. PMID- 7253100 SO - J Wildl Dis 1981 Jan;17(1):39-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81242565 AU - Drewek J Jr AU - Noon TH AU - Trautman RJ AU - Bicknell EJ TI - Serologic evidence of leptospirosis in a southern Arizona coyote population. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Arizona MH - Carnivora/*immunology MH - Case Report MH - Kidney/pathology MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/pathology/*veterinary MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810922 DP - 1981 Jan IS - 0090-3558 TA - J Wildl Dis PG - 33-7 SB - M CY - UNITED STATES IP - 1 VI - 17 JC - KEM EM - 8111 PMID- 7253099 CU - 91 SO - J Wildl Dis 1981 Jan;17(1):33-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 81240734 AU - Kiktenko VS AU - Volina EG AU - Sarukhanova LE TI - To the problem of culture-morphological peculiarities of leptospiral colonies on solid nutrient media. LA - Eng MH - Comparative Study MH - Culture Media MH - Leptospira/*cytology/growth & development/pathogenicity MH - Time Factors RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 810915 DP - 1981 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 144-9 SB - M CY - CZECHOSLOVAKIA IP - 2 VI - 25 JC - IEV EM - 8111 PMID- 7252143 CU - 91 SO - J Hyg Epidemiol Microbiol Immunol 1981;25(2):144-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 81183235 AU - Pannwitz S AU - Riechert D AU - Wolter F AU - Franze F TI - [Control of veterinary communicable diseases in swine and fattening cattle stocks by serological testing of slaughtered animal blood samples] LA - Ger MH - Abattoirs MH - Animal MH - Brucellosis/prevention & control/veterinary MH - Brucellosis, Bovine/prevention & control MH - Cattle MH - Cattle Diseases/*prevention & control MH - Communicable Disease Control MH - English Abstract MH - Leptospirosis/prevention & control/veterinary MH - Serodiagnosis/methods/*veterinary MH - Specimen Handling/methods MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 810625 DP - 1981 IS - 0003-9055 TA - Arch Exp Veterinarmed PG - 19-30 SB - M CY - GERMANY, EAST IP - 1 VI - 35 JC - 70I AA - Author EM - 8108 AB - Economy of prophylactic haemoserological control of pig stocks in a district as well as of a sow breeding unit and of cattle stocks on two industrialised fattening farms has been enhanced by including blood samples from routine slaughtering. Preliminary organisational experience is reported in this paper. The samples collected samples collected from normally slaughtered selected sows may contribute to an improvement of veterinary production control. PMID- 7224789 CU - 84 TT - Seuchenkontrolle in Schweine- und Mastrinderbestanden durch serologische Untersuchung von Schlachttierblutproben. EA - A SO - Arch Exp Veterinarmed 1981;35(1):19-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81174336 AU - Faine S TI - Leptospirosis--here, now [editorial] LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Australia MH - Bacterial Vaccines/therapeutic use MH - Cattle MH - Disease Vectors MH - Human MH - Leptospira/classification MH - *Leptospirosis MH - Penicillins/therapeutic use MH - Serodiagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) RN - 0 (Penicillins) PT - EDITORIAL DA - 810613 DP - 1981 Jan IS - 0031-3025 TA - Pathology PG - 1-5 SB - M CY - AUSTRALIA IP - 1 VI - 13 JC - OTA EM - 8108 PMID- 7220092 CU - 92 SO - Pathology 1981 Jan;13(1):1-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 82087014 AU - Cinco M AU - Banfi E AU - Mailloux M TI - Isolation and classification of fifteen strains of saprophytic leptospires isolated from surface water in France and other countries. LA - Eng MH - France MH - Fresh Water MH - Leptospira/classification/*isolation & purification/pathogenicity MH - Micropore Filters MH - Serotyping MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 820212 DP - 1981 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 538-42 SB - M CY - GERMANY, WEST IP - 4 VI - 249 JC - Y5N EM - 8204 PMID- 7198353 CU - 90 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1981;249(4):538-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81198234 AU - Blackmore DK AU - Marshall RB AU - MacKintosh CM TI - Alternative strategies for the control of leptospirosis in dairy herds. LA - Eng MH - Animal MH - Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Leptospirosis/prevention & control/*veterinary MH - Vaccination/*veterinary RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 810709 DP - 1981 Jan-Feb IS - 0048-0169 TA - N Z Vet J PG - 19-20 CY - NEW ZEALAND IP - 1-2 VI - 29 JC - OBZ EM - 8109 PMID- 6940048 CU - 91 SO - N Z Vet J 1981 Jan-Feb;29(1-2):19-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 81198233 AU - Mackintosh CG AU - Marshall RB AU - Thompson JC TI - Experimental infection of sheep and cattle with Leptospira interrogans serovar balcanica. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology/pathology MH - Female MH - Kidney/microbiology MH - Leptospira interrogans/pathogenicity MH - Sheep MH - Sheep Diseases/*microbiology/pathology MH - Weil's Disease/microbiology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 810709 DP - 1981 Jan-Feb IS - 0048-0169 TA - N Z Vet J PG - 15-9 CY - NEW ZEALAND IP - 1-2 VI - 29 JC - OBZ EM - 8109 PMID- 6940047 CU - 88 SO - N Z Vet J 1981 Jan-Feb;29(1-2):15-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82087015 AU - Metcalfe RV AU - Bettelheim KA AU - Densham EB AU - Pearce J AU - Sillars H AU - Thorn C TI - Studies on antibody levels to Brucella abortus, Toxoplasma gondii and Leptospira serogroups in sera collected in five locations of the North Island of New Zealand. LA - Eng MH - Adult MH - Antibodies/*analysis MH - Antibodies, Bacterial/*analysis MH - Brucella abortus/*immunology MH - Female MH - Human MH - Leptospira/*immunology MH - Male MH - Middle Age MH - New Zealand MH - Rural Population MH - Toxoplasma/*immunology MH - Urban Population RN - 0 (Antibodies) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 820212 DP - 1981 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 543-56 SB - M CY - GERMANY, WEST IP - 4 VI - 249 JC - Y5N EM - 8204 PMID- 6797151 CU - 91 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1981;249(4):543-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [5 medline neighbors] UI - 81242561 AU - Wells EA AU - D'Alessandro A AU - Morales GA AU - Angel D TI - Mammalian wildlife diseases as hazards to man and livestock in an area of the Llanos Orientales of Colombia. LA - Eng MH - Animal MH - Animal Diseases/*epidemiology MH - *Animals MH - Animals, Domestic MH - *Animals, Wild MH - Arbovirus Infections/epidemiology/veterinary MH - Chagas Disease/epidemiology/veterinary MH - Colombia MH - Helminthiasis/epidemiology/veterinary MH - Human MH - Zoonoses PT - JOURNAL ARTICLE DA - 810922 DP - 1981 Jan IS - 0090-3558 TA - J Wildl Dis PG - 153-62 SB - M CY - UNITED STATES IP - 1 VI - 17 JC - KEM AA - Author EM - 8111 AB - Development of the LLanos Orientales of Colombia, and access to underdeveloped areas in the Llanos, may create disease hazards to man and domestic animals or introduce exotic pathogens, creating reservoirs of infection for domestic animals and acting as limiting factors on the native wild species. A survey of wild animals common to the Llanos revealed a number of parasites indigenous to the area. A total total of 59 mammalian species, representing eight orders were examined. Haematozoa were represented by Trypanosoma cruzi, T. evansi and T. rangeli. Eight species of ticks were found: Amblyomma cajennense, A. auricularium, A. rotundatum, A. maculatum, A. longirostre, A. pacae, Ixodes luciae and Boophilus microplus. Four species of fleas were found: Rhopalopsyllus lugubris lugubris, R. australis tupinus, R. cacicus saevus and Polygenis klagesi samuelis. A species of Echinococcus was commonly found in Cuniculus paca. Serologic titers and/or isolations of pathogenic viral and bacterial agents generally indicated that the wildlife population had not been exposed to the diseases common to the domestic population. A low prevalence of titers to Venezuelan equine encephalomyelitis was found in Cebus apella and Proechimys sp. Neutralizing antibodies to Group B viruses were found in Proechimys sp., Coendor sp. and Nectomys squamipes. Antibodies to Group C viruses were found in Proechimys sp. Serologic titers to Leptospira sejroe and L. tarassovi were found in Proechimys sp. and Didelphis marsupialis. L. tarassovi was isolated from Proechimys sp. Titers to Brucella were not found in 1964 animals. The significance of these findings are discussed. RO - M:BDS PMID- 6788961 LR - 870410 CU - 91 SO - J Wildl Dis 1981 Jan;17(1):153-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81240739 AU - Tagi-Zade TA AU - Alekperov FP AU - Agayev IA TI - Natural foci of leptospirosis on the territory of the north-eastern part of the east mountain range of Azerbaijan and their characteristic. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Azerbaijan MH - Ecology MH - Insectivora/*microbiology MH - Leptospira/classification/immunology MH - Leptospirosis/epidemiology/*veterinary MH - Rodent Diseases/*epidemiology MH - Rodentia/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810915 DP - 1981 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 175-80 SB - M CY - CZECHOSLOVAKIA IP - 2 VI - 25 JC - IEV AA - Author EM - 8111 AB - Numerous natural foci of leptospirosis infection in which Ap. sylvaticus and M. musculus play the role of the main source, were found on the territory of the north-eastern part of Azerbaijan's east mountain range. The leading place in the aetiological structure of leptospirosis of small mammals is occupied by leptospirae of the serological group Hebdomadis. As a rule, the animals -- Leptospira- carriers -- populate damp biotopes where stable natural foci of disease are formed. Two types of natural foci were established on the given territory, i. e., the marshy-bush type and the mountain-stream type. The foci are characterized by several hosts and several serotypes of Leptospira. PMID- 6454722 CU - 92 SO - J Hyg Epidemiol Microbiol Immunol 1981;25(2):175-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 81242562 AU - Amundson TE AU - Yuill TM TI - Prevalence of selected pathogenic microbial agents in the red fox (Vulpes fulva) and gray fox (Urocyon cinereoargenteus) of southwestern Wisconsin. LA - Eng MH - Adenoviruses, Canine/immunology MH - Animal MH - Antibodies/*analysis MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/analysis MH - Comparative Study MH - Distemper Virus, Canine/immunology MH - Foxes/*immunology MH - Leptospira/immunology MH - Leptospira interrogans/immunology MH - Wisconsin RN - 0 (Antibodies) RN - 0 (Antibodies, Bacterial) RN - 0 (Antibodies, Viral) PT - JOURNAL ARTICLE DA - 810922 DP - 1981 Jan IS - 0090-3558 TA - J Wildl Dis PG - 17-22 SB - M CY - UNITED STATES IP - 1 VI - 17 JC - KEM AA - Author EM - 8111 AB - Free-ranging red foxes (Vulpes fulva) and gray foxes (Urocyon cinereoargenteus) were trapped in southwestern Wisconsin. Fox sera were tested to determine the prevalence of antibody for five different Leptospira interrogans serovars, canine distemper virus (CDV), infectious canine hepatitis virus (ICHV), and Franciscella tularensis infections. Grippotyphosa was the most prevalent leptospiral serovar antibody observed. Twenty-five of 53 (47%) red foxes and 11 of 36 (31%) gray foxes had specific antibodies to grippotyphosa. Juvenile foxes had geometric mean antibody titers to grippotyphosa significantly higher (P less than 0.05) than those of the adults of both species. CDV antibody was detected in sera of red foxes only. Six of 57 (11%) red foxes had CDV antibody. ICHV antibody was detected in 2 of 57 (3%) red foxes and 3 of 32 (9%) gray foxes. Antibody to F. tularensis was not detected in any fox sera. PMID- 6265659 CU - 93 SO - J Wildl Dis 1981 Jan;17(1):17-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 82087023 AU - Torres J AU - Yanagawa R AU - Ono E TI - Inhibition of Leptospiricidal reaction by the type-specific main antigen of Leptospira. LA - Eng MH - Animal MH - Antibodies, Bacterial/*immunology MH - Antigen-Antibody Reactions MH - Antigens, Bacterial/*immunology MH - Complement/immunology MH - Epitopes MH - Guinea Pigs/immunology MH - Leptospira interrogans/*immunology MH - Rabbits MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) RN - 9007-36-7 (Complement) PT - JOURNAL ARTICLE DA - 820212 DP - 1981 TA - Zentralbl Bakteriol Mikrobiol Hyg [A] PG - 147-52 SB - M CY - GERMANY, WEST IP - 1-2 VI - 250 JC - Y5N AA - Author EM - 8204 AB - The serovar-specificity of the leptospiricidal activity test mediated by antiserum and complement was demonstrated by the fact that the leptospiricidal activity of the antiserum against the serovar-specific main (TM) antigen of copenhageni shibaura and the antiserum against the whole cells of the same strain were inhibited by the homologous but not the heterologous TM antigens. The inoculation of TM antigen produced in a rabbit the antibodies which react in the leptospiricidal activity test. These results may also show that the substance which participates in the leptospiricidal activity test may be the TM antigen. PMID- 6171950 CU - 95 SO - Zentralbl Bakteriol Mikrobiol Hyg [A] 1981;250(1-2):147-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81195650 AU - Stoianova NA AU - Khazenson SL TI - [Determination of the antibody class in Leptospira infection] LA - Rus MH - Antibodies, Bacterial/analysis/*classification MH - Convalescence MH - English Abstract MH - Human MH - IgG/analysis MH - IgM/analysis MH - Immunoglobulins, Fc/immunology MH - Immunologic Techniques MH - Leptospira/*immunology MH - Leptospirosis/*immunology MH - Staphylococcal Protein A/immunology RN - 0 (Antibodies, Bacterial) RN - 0 (Immunoglobulins, Fc) PT - JOURNAL ARTICLE DA - 810709 DP - 1981 IS - 0023-6748 TA - Lab Delo PG - 174-6 CY - USSR IP - 3 JC - KYU EM - 8109 PMID- 6164838 CU - 95 TT - Opredelenie klassa antitel pri leptospiroznoi infektsii. EA - A SO - Lab Delo 1981;(3):174-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 81274521 AU - Yasuda PH AU - Santa Rosa CA AU - Yanaguita RM TI - [Seasonal variation in the prevalence of leptospirosis in stray dogs in Sao Paulo, Brazil] LA - Por MH - Agglutination Tests MH - Animal MH - Brazil MH - Dog Diseases/*epidemiology MH - Dogs MH - English Abstract MH - Leptospirosis/*veterinary MH - *Seasons PT - JOURNAL ARTICLE DA - 811025 DP - 1980 Dec IS - 0034-8910 TA - Rev Saude Publica PG - 589-96 CY - BRAZIL IP - 4 VI - 14 JC - T5X EM - 8112 PMID- 7268298 CU - 88 TT - Variacao sazonal na prevalencia de leptospirose em caes de rua da cidade de Sao Paulo, Brasil. EA - A SO - Rev Saude Publica 1980 Dec;14(4):589-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [68 medline neighbors] UI - 81267925 AU - Otani S AU - Akama K TI - Analyses for neutralizing activities of immunoglobulin fractions in anti-leptospiral horse antiserum. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Chromatography, Gel MH - Comparative Study MH - Electrophoresis MH - Guinea Pigs MH - Horses/immunology MH - Immune Sera/*analysis MH - Immunoglobulins/*analysis MH - Leptospira interrogans/*immunology MH - Male MH - Neutralization Tests RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 811025 DP - 1980 Dec IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 295-301 SB - M CY - JAPAN IP - 6 VI - 33 JC - KLZ AA - Author EM - 8112 AB - The 7S and 19S fraction isolated from hyperimmunized antileptospiral horse sera by Sephadex G-200 gel filtration and gamma- and T-globulin fractions from the antisera by starch block electrophoresis were studied for neutralizing (leptospiricidal) activities against infection with Leptospira. The activity was determined by the intracutaneous method with virulent Shibaura Strain of Leptospira interrogans serovar copenhageni. No significant difference in regression coefficient was observed between the neutralization line with the 19S globulin fraction and that with the 7S globulin fraction, whereas a significant difference in the regression coefficient was observed when the gamma- and T-globulin fractions were compared; the regression coefficient with T-globulin was consistently larger than that with gamma-globulin. PMID- 7265554 CU - 91 SO - Jpn J Med Sci Biol 1980 Dec;33(6):295-301 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81252174 AU - Zhang ZX AU - Dong RW AU - Shu GX AU - Ling ZJ AU - Sheng XY AU - Wang LH TI - [The synthesis of "methimidol" and its derivatives--a new antileptospirosis drug (author's transl)] LA - Chi MH - Animal MH - Anti-Infective Agents/*chemical synthesis/therapeutic use MH - English Abstract MH - Female MH - Hamsters MH - Imidazoles/*chemical synthesis MH - Leptospirosis/drug therapy MH - Male RN - 0 (Anti-Infective Agents) RN - 0 (Imidazoles) RN - 1615-15-2 (methimidol) PT - JOURNAL ARTICLE DA - 810925 DP - 1980 Dec TA - Yao Hsueh Hsueh Pao PG - 719-24 CY - CHINA IP - 12 VI - 15 JC - 1PU EM - 8111 RO - M:DLJ PMID- 7257797 LR - 840806 CU - 91 EA - A SO - Yao Hsueh Hsueh Pao 1980 Dec;15(12):719-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 81238947 AU - Everard CO AU - Sulzer CR AU - Bhagwandin LJ AU - Fraser-Chanpong GM AU - James AC TI - Pathogenic leptospira isolates from the Caribbean Islands of Trinidad, Grenada and St. Vincent. LA - Eng MH - Animal MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/transmission MH - Serotyping MH - Trinidad and Tobago MH - West Indies PT - JOURNAL ARTICLE DA - 810922 DP - 1980 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 90-100 SB - M CY - TAIWAN IP - 2 VI - 7 JC - GTK AA - Author EM - 8111 AB - All known isolates of Leptospira interrogans obtained in Trinidad, Grenada and St. Vincent up to the end of 1979 are listed. There were 80 from Trinidad, 20 from Grenada and 2 from St. Vincent, representing at least 20 serotypes from 11 or more serogroups. Six of the serotypes were first reported from Trinidad. The leptospires were isolated from man, domestic animals and wildlife species. PMID- 7251267 SO - Int J Zoonoses 1980 Dec;7(2):90-100 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81238944 AU - Hyakutake S AU - Biasi PD AU - Belluomini HE AU - Santa Rosa CA TI - Leptospiroses in Brazilian snakes. LA - Eng MH - Animal MH - Brazil MH - Female MH - Leptospirosis/diagnosis/*veterinary MH - Male MH - Serodiagnosis MH - Snakes/*microbiology PT - JOURNAL ARTICLE DA - 810922 DP - 1980 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 73-7 SB - M CY - TAIWAN IP - 2 VI - 7 JC - GTK EM - 8111 PMID- 7251265 SO - Int J Zoonoses 1980 Dec;7(2):73-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 81238941 AU - Santa Rosa CA AU - Sulzer CR AU - de Castro AF AU - Yanaguita RM AU - Giorgi W TI - Two new leptospiral serovars in the Hebdomadis group isolated from cattle in Brazil. LA - Eng MH - Animal MH - Brazil MH - Cattle/*microbiology MH - Leptospira/classification/immunology/*isolation & purification PT - JOURNAL ARTICLE DA - 810922 DP - 1980 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 158-63 SB - M CY - TAIWAN IP - 2 VI - 7 JC - GTK AA - Author EM - 8111 AB - Two leptospiral serovars belonging to the Hebdomadis Serogroup are described. These strains are represented by two isolations from apparently healthy zebu cattle. It is proposed that the serovars be designated guaicurus strain Bov. G and goiano strain Bov. 131. PMID- 7251262 SO - Int J Zoonoses 1980 Dec;7(2):158-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 81238940 AU - Hagiwara MK AU - Santa Rosa CA AU - Pinto AA TI - Comparative study between microscopic agglutination and complement fixation tests in experimental canine leptospirosis. LA - Eng MH - *Agglutination Tests MH - Animal MH - Antibody Formation MH - Comparative Study MH - *Complement Fixation Tests MH - Dogs MH - Leptospirosis/*immunology PT - JOURNAL ARTICLE DA - 810922 DP - 1980 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 150-7 SB - M CY - TAIWAN IP - 2 VI - 7 JC - GTK AA - Author EM - 8111 AB - In order to evaluate the antibody response to pathologic leptospira from both serovars icterohaemorrhagiae and canicola, dogs were experimentally inoculated with these leptospiras. Each of the serovar were inoculated in 15 dogs and the antibody response in the acute phase of infected was followed by microscopic agglutination and complement fixation tests. Complement fixing antibodies were detected in both groups at the 4th day post infection and agglutinins appeared in circulation at the 7th day post infection when homologous antigens were used. On the 63rd day post infection with serovar canicola and on 56th day post infection with serovar icterohaemorrhagiae, complement fixing antibodies could no longer be detected but, in both experimental groups, specific agglutinins were presented in significant titers. PMID- 7251261 SO - Int J Zoonoses 1980 Dec;7(2):150-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81238937 AU - Yasuda PH AU - Santa Rosa CA AU - Myers DM AU - Yanaguita RM TI - The isolation of leptospires from stray dogs in the city of Sao Paulo, Brazil. LA - Eng MH - Animal MH - Brazil MH - *Disease Reservoirs MH - Dogs/*microbiology MH - Female MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology MH - Male MH - Seasons PT - JOURNAL ARTICLE DA - 810922 DP - 1980 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 131-4 SB - M CY - TAIWAN IP - 2 VI - 7 JC - GTK AA - Author EM - 8111 AB - The search of leptospires was conducted in kidneys of 1,415 stray dogs in the city of Sao Paulo--Brazil. From them 35 isolations were got, serovar canicola was the most frequent (32 samples) followed by copenhageni (2 samples) and pomona (1 sample). For the first time serovar pomona was isolated from dog in Latin America. Also, monthly and seasonal variations are discussed in relation to the prevalence of leptospirosis. PMID- 7251258 CU - 88 SO - Int J Zoonoses 1980 Dec;7(2):131-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 82036551 AU - Mackintosh CG AU - Marshall RB AU - Blackmore DK TI - Leptospira interrogans serovar balcanica in cattle [letter] LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*immunology MH - Leptospira interrogans/*immunology/isolation & purification MH - Leptospirosis/immunology/*veterinary RN - 0 (Antibodies, Bacterial) PT - LETTER DA - 811216 DP - 1980 Dec IS - 0048-0169 TA - N Z Vet J PG - 268 CY - NEW ZEALAND IP - 12 VI - 28 JC - OBZ EM - 8202 PMID- 6945519 CU - 91 SO - N Z Vet J 1980 Dec;28(12):268 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82036548 AU - Flint SH AU - Liardet DM TI - A trivalent leptospiral vaccine with emphasis on a Leptospira interrogans serovar hardjo component to prevent leptospiruria. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/immunology/*prevention & control/urine MH - Hamsters MH - Leptospira interrogans/*immunology/metabolism MH - Leptospirosis/prevention & control/urine/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 811216 DP - 1980 Dec IS - 0048-0169 TA - N Z Vet J PG - 263-6 CY - NEW ZEALAND IP - 12 VI - 28 JC - OBZ EM - 8202 PMID- 6945516 CU - 91 SO - N Z Vet J 1980 Dec;28(12):263-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 82036546 AU - Mackintosh CG AU - Schollum LM AU - Harris RE AU - Blackmore DK AU - Willis AF AU - Cook NR AU - Stoke JC TI - Epidemiology of leptospirosis in dairy farm workers in the Manawatu. Part I: A cross-sectional serological survey and associated occupational factors. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/transmission MH - Dairying MH - Female MH - Human MH - Leptospirosis/*epidemiology/immunology/transmission/veterinary MH - Male MH - New Zealand MH - Occupational Diseases/epidemiology/immunology MH - Risk MH - Swine MH - Swine Diseases/transmission RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 811216 DP - 1980 Dec IS - 0048-0169 TA - N Z Vet J PG - 245-50 CY - NEW ZEALAND IP - 12 VI - 28 JC - OBZ EM - 8202 PMID- 6945514 CU - 91 SO - N Z Vet J 1980 Dec;28(12):245-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 81163438 AU - Parrinello AE AU - Balestriero C TI - [Case of digestive hemorrhage due to leptospirosis (Weil's disease) treated with cimetidine] LA - Ita MH - Case Report MH - Cimetidine/*therapeutic use MH - English Abstract MH - Gastrointestinal Hemorrhage/*drug therapy/etiology MH - Guanidines/*therapeutic use MH - Human MH - Male MH - Middle Age MH - Weil's Disease/*drug therapy RN - 0 (Guanidines) RN - 51481-61-9 (Cimetidine) PT - JOURNAL ARTICLE DA - 810613 DP - 1980 Nov 30 IS - 0009-9074 TA - Clin Ter PG - 459-62 CY - ITALY IP - 4 VI - 95 JC - DKN EM - 8108 PMID- 6971207 CU - 91 TT - Considerazioni su un caso di emorragia digestiva alta da leptospirosi (m. di Weil) trattata con cimetidina. EA - A SO - Clin Ter 1980 Nov 30;95(4):459-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81128203 AU - Ugriumov BL AU - Vovk AD AU - Tat'ianko NV AU - Iurkovskaia NB AU - Kudriavtseva NG TI - [Analysis of diagnostic errors in leptospirosis] LA - Rus MH - Adult MH - Animal MH - Bites and Stings MH - Case Report MH - Diagnosis, Differential MH - Diagnostic Errors MH - English Abstract MH - Hepatitis, Viral, Human/*diagnosis MH - Human MH - Leptospirosis/*diagnosis/transmission MH - Male MH - Rodentia PT - JOURNAL ARTICLE DA - 810424 DP - 1980 Nov IS - 0049-6804 TA - Vrach Delo PG - 112-6 CY - USSR IP - 11 JC - XLS EM - 8106 PMID- 7467248 TT - Analiz diagnosticheskikh oshibok pri leptospiroze. EA - A SO - Vrach Delo 1980 Nov;(11):112-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81122610 AU - Diesch SL TI - Leptospirosis: vaccination and titer evaluation. LA - Eng MH - Animal MH - Animals, Domestic/*immunology MH - Antibodies, Bacterial/*analysis MH - Cattle/immunology MH - Comparative Study MH - Horses/immunology MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Sheep/immunology MH - Swine/immunology MH - Vaccination/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810424 DP - 1980 Nov IS - 0362-8140 TA - Mod Vet Pract PG - 905-8 SB - M CY - UNITED STATES IP - 11 VI - 61 JC - NGO EM - 8106 PMID- 7464764 CU - 91 SO - Mod Vet Pract 1980 Nov;61(11):905-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81093787 AU - Douglass EM AU - Plue RE TI - Hemolytic anemia suggestive of leptospirosis in the black rhinoceros. LA - Eng MH - Anemia, Hemolytic/etiology/pathology/*veterinary MH - Animal MH - *Animals, Zoo MH - Case Report MH - Female MH - Leptospirosis/complications/pathology/*veterinary MH - Male MH - *Perissodactyla PT - JOURNAL ARTICLE DA - 810317 DP - 1980 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 921-3 SB - M CY - UNITED STATES IP - 9 VI - 177 JC - HAV EM - 8105 PMID- 7451343 SO - J Am Vet Med Assoc 1980 Nov 1;177(9):921-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [93 medline neighbors] UI - 81086803 AU - Crawford SM AU - Miles DW TI - Leptospira hebdomadis associated with an outbreak of illness in workers on a farm in North Yorkshire. LA - Eng MH - Adult MH - Agricultural Workers' Diseases/complications/*epidemiology MH - Case Report MH - Disease Outbreaks/*epidemiology MH - England MH - Human MH - Leptospirosis/complications/*epidemiology MH - Male MH - Meningitis/etiology PT - JOURNAL ARTICLE DA - 810317 DP - 1980 Nov IS - 0007-1072 TA - Br J Ind Med PG - 397-8 SB - M CY - ENGLAND IP - 4 VI - 37 JC - AXS AA - Author EM - 8105 AB - Four cases of illness attributed to Leptospira hebdomadis occurred on a cattle farm in North Yorkshire. The clinical features were a febrile illness that resembled influenza; in one case there was a lymphocytic meningitis. This infection is probably more common than is recognised at present, and prevention of further cases may be possible if diagnosed promptly. PMID- 7448136 CU - 88 SO - Br J Ind Med 1980 Nov;37(4):397-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 81078925 AU - Tenenbaum MJ AU - Markowitz SM TI - Rocky Mountain spotted fever: diagnostic dilemma of the atypical presentation. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Case Report MH - Child MH - Complement Fixation Tests MH - Diagnosis, Differential MH - Gastroenteritis/diagnosis MH - Hepatitis, Viral, Human/diagnosis MH - Human MH - Leptospirosis/diagnosis MH - Male MH - Rocky Mountain Spotted Fever/complications/*diagnosis PT - JOURNAL ARTICLE DA - 810224 DP - 1980 Nov IS - 0038-4348 TA - South Med J PG - 1527-9 SB - A SB - M CY - UNITED STATES IP - 11 VI - 73 JC - UVH AA - Author EM - 8104 AB - Two patients with Rocky Mountain spotted fever presented with atypical manifestations which led to a delay in diagnosis and treatment. Such clinical manifestations occurring in endemic areas during warm months should not eliminate consideration of the proper diagnosis. If RMSF cannot be ruled out, therapeutic regimens should include appropriate antimicrobial coverage. PMID- 7444527 SO - South Med J 1980 Nov;73(11):1527-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [94 medline neighbors] UI - 81232162 AU - de Fredrick DF AU - Reece RL TI - Diseases of cattle in the Solomon Islands. LA - Eng MH - Animal MH - Brucellosis, Bovine/epidemiology MH - Cattle MH - Cattle Diseases/*epidemiology MH - Keratoconjunctivitis/epidemiology/veterinary MH - Leptospirosis/epidemiology/veterinary MH - Melanesia MH - Nematode Infections/epidemiology/veterinary MH - Support, Non-U.S. Gov't MH - Trematode Infections/epidemiology/veterinary MH - Tuberculosis, Bovine/epidemiology PT - JOURNAL ARTICLE DA - 810810 DP - 1980 Nov IS - 0005-0423 TA - Aust Vet J PG - 522-5 SB - M CY - AUSTRALIA IP - 11 VI - 56 JC - 9IE AA - Author EM - 8110 AB - Between 1967 and 1977 a study was made of diseases of cattle in the Solomon Islands. Tuberculosis was found in only 3 herds and was eradicated by 1975. Brucellosis serology revealed very few reactors and by 1977 the herds involved were considered free of the disease. Significant serological reactions were found to Leptospira interrogans serovars pomona, hardjo, autumnalis and jez-bratislava. There was evidence that infectious bovine rhinotracheitis and mucosal disease were present. Seventeen parasites were identified of which Haematobia irritans exigua, Haemonchus placei, Oesophagostomum radiatum and Ceylonocotyle streptocoelium were widely distributed. Nutritional stress occurred under some forms of husbandry but environmental stress was minimal. The Solomon Islands are therefore in a most favourable situation with regard to diseases of cattle. PMID- 7247885 CU - 88 SO - Aust Vet J 1980 Nov;56(11):522-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81211471 AU - Wang DQ TI - [Isolation of pathogenic leptospirae from frog urine and kidneys (author's transl)] LA - Chi MH - Animal MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Ranidae/*microbiology MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 810820 DP - 1980 Nov TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 221-2 CY - CHINA IP - 4 VI - 14 JC - D74 EM - 8110 PMID- 7238187 SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1980 Nov;14(4):221-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [41 medline neighbors] UI - 81179722 AU - Cinco M AU - Banfi E AU - Furlani A AU - Scarcia V TI - Cytotoxic activity of supernatant extracts of virulent and saprophytic leptospires. LA - Eng MH - Animal MH - Bacterial Toxins/*pharmacology MH - Cells, Cultured MH - Cytotoxins/*pharmacology MH - Fibroblasts/cytology/drug effects MH - Guinea Pigs MH - Heat MH - *Leptospira/pathogenicity MH - *Leptospira interrogans/pathogenicity MH - Mice MH - Species Specificity MH - Trypsin/pharmacology MH - Virulence RN - EC 3.4.21.4 (Trypsin) RN - 0 (Bacterial Toxins) RN - 0 (Cytotoxins) PT - JOURNAL ARTICLE DA - 810613 DP - 1980 Nov IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 260-7 SB - M CY - GERMANY, WEST IP - 2 VI - 248 JC - Y5P AA - Author EM - 8108 AB - Extracts from supernatants, obtained from culture of virulent strain PB- 3 and saprophytic strain Isola Sacra 1, were assayed for cytotoxicity. A cytotoxic factor produced by the pathogenic strain was found to affect specifically the tested cells, at determined concentrations; on the other side a not clear and scarce cytotoxicity was shown for the extract from the saprophytic strain Isola Sacra 1. Cytotoxic factor produced by strain PB-3 was heat resistant and trypsin sensitive, suggesting to be a thermostable protein. An inhibitory doses it induced a typical, cytopathic effect on the treated cells. PMID- 7223124 CU - 92 SO - Zentralbl Bakteriol [A] 1980 Nov;248(2):260-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [49 medline neighbors] UI - 81093759 AU - Medway W TI - Some bacterial and mycotic diseases of marine mammals. LA - Eng MH - Actinomycetales Infections/veterinary MH - Animal MH - Bacterial Infections/*veterinary MH - Blastomycosis/veterinary MH - Candidiasis/veterinary MH - *Cetacea MH - Clostridium Infections/veterinary MH - Dolphins MH - Erysipelothrix Infections/diagnosis MH - Histoplasmosis/veterinary MH - Leptospirosis/veterinary MH - Mycoses/*veterinary MH - *Pinnipedia MH - Pseudomonas Infections/veterinary MH - Seals MH - Sporotrichosis/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 810317 DP - 1980 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 831-4 SB - M CY - UNITED STATES IP - 9 VI - 177 JC - HAV EM - 8105 RF - 44 PMID- 7005206 CU - 90 SO - J Am Vet Med Assoc 1980 Nov 1;177(9):831-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81123563 AU - Ris DR AU - Hamel KL TI - The preliminary differentiation with factor sera of Leptospira interrogans serovars hardjo and balcanica. LA - Eng MH - Animal MH - Cattle/*immunology MH - Leptospira/*immunology MH - Leptospira interrogans/*immunology MH - Opossums/*immunology MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 810421 DP - 1980 Nov IS - 0048-0169 TA - N Z Vet J PG - 243-4 CY - NEW ZEALAND IP - 11 VI - 28 JC - OBZ EM - 8106 PMID- 6936674 CU - 88 SO - N Z Vet J 1980 Nov;28(11):243-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 81049587 AU - Fathalla NC AU - Coghlan JD TI - Detection of leptospiral antibodies in animal sera by means of fractionated antigenic extracts. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial MH - Cattle MH - Dogs MH - Epitopes MH - Fractionation MH - Leptospira/classification/*immunology MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Rabbits RN - 0 (Antibodies, Bacterial) RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 810129 DP - 1980 Nov IS - 0022-2615 TA - J Med Microbiol PG - 513-26 SB - M CY - ENGLAND IP - 4 VI - 13 JC - J2N AA - Author EM - 8103 AB - Sodium dodecyl sulphate extracts of the reference strains Mus 127, Castellon 3 and Arborea of the Ballum agglutinogenic serogroup of Leptospira interrogans (the species of pathogenic leptospira), of strain Patoc 1 of the saprophytic species of L. biflexa, and of strain 3055 of illini serotype, the sole representative of L. illini, were each fractionated by ultracentrifugation in a sucrose density gradient into 10 fractions. The fractions were tested by complement fixation and immunodiffusion against the sera of animals during the process of immunisation and during the course of naturally occurring infections. The fractions could be divided into three main pools of serological activity: pool I (fractions 1, 2 and 3), pool II (fractions 4, 5 and 6), pool III (fractions 7, 8 and 9). Pool I was species/genus specific; fraction 1 tended to be species specific while fraction 2 reacted with antisera to all strains whether pathogenic or saprophytic. Pool II was serogroup specific and reacted only with antisera to members of the same serogroup. Pool III was serotype (serovar) specific and revealed the identity of the infecting strain at an early stage of infection. PMID- 6159474 CU - 95 SO - J Med Microbiol 1980 Nov;13(4):513-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [79 medline neighbors] UI - 81125430 AU - Mailloux M TI - [Leptospirosis and environment (author's transl)] LA - Fre MH - English Abstract MH - Environment MH - Human MH - Leptospirosis/*etiology/transmission MH - Occupational Diseases/*etiology PT - JOURNAL ARTICLE DA - 810421 DP - 1980 Oct 30 IS - 0398-7620 TA - Rev Epidemiol Sante Publique PG - 323-9 SB - M CY - FRANCE IP - 3 VI - 28 JC - RST AA - Author EM - 8106 AB - Occupational groups are divided into two groups: 1. Direct contact with animals (14 per cent): veterinary work, hunting, slaughtering, butchers and pork-butchers' work. 2. Contact with natural environment. Transmission is indirect, through water, aquatic environment: stall- keepers, drivers dealing with dumping grounds, scavengers, persons working underground, in cellars, sewers, and particularly agricultural workers, market-gardeners, cattle raisers; bathers and anglers who have direct contact with water. This mode of transmission: rural areas, agriculture, is recorded in 38 per cent of the cases. Contamination through water represents 27 per cent. Leptospiral diseases occur in 4/5 of the cases when Man is in contact with Nature. In most cases, 86 per cent, Leptospirosis is an environmental disease caused by wet ground, aquatic environment. PMID- 7465927 TT - Leptospiroses et environnement. EA - A SO - Rev Epidemiol Sante Publique 1980 Oct 30;28(3):323-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81132478 AU - Morgan AG AU - Cawich F TI - Ascending polyneuropathy in leptospirosis--a case study. LA - Eng MH - Aged MH - Case Report MH - Female MH - Human MH - Leptospirosis/*complications/immunology MH - Quadriplegia/*etiology/immunology PT - JOURNAL ARTICLE DA - 810413 DP - 1980 Oct IS - 0003-4983 TA - Ann Trop Med Parasitol PG - 567-8 SB - M CY - ENGLAND IP - 5 VI - 74 JC - 68E EM - 8106 PMID- 7469571 SO - Ann Trop Med Parasitol 1980 Oct;74(5):567-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81064235 AU - Higgins R AU - Desilets A AU - Rene-Roberge E TI - Serological survey of leptospiral antibodies in swine in Quebec. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/*veterinary MH - Support, Non-U.S. Gov't MH - Swine MH - Swine Diseases/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810226 DP - 1980 Oct IS - 0008-5286 TA - Can Vet J PG - 278-9 CY - CANADA IP - 10 VI - 21 JC - CLS EM - 8104 PMID- 7438003 CU - 91 SO - Can Vet J 1980 Oct;21(10):278-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81038601 AU - Short RC TI - Leptospirosis. LA - Eng MH - Agricultural Workers' Diseases/diagnosis MH - Animal MH - Animal Husbandry MH - Australia MH - Cattle MH - Diagnosis, Differential MH - Dogs MH - Horses/microbiology MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis/epidemiology/microbiology MH - Mice MH - Opossums/microbiology MH - Rats MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 801218 DP - 1980 Oct IS - 0300-8495 TA - Aust Fam Physician PG - 685-6 SB - M CY - AUSTRALIA IP - 10 VI - 9 JC - 9EC AA - Author EM - 8102 AB - Leptospirosis is not one specfic disease, as may be thought, but a series of separate diseases, each with distinct clinical features. Although uncommon, it is not a rare disease, and it can occur in pet owners, those in the livestock industry, and agricultural workers. PMID- 7425958 CU - 88 SO - Aust Fam Physician 1980 Oct;9(10):685-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [94 medline neighbors] UI - 82055938 AU - Otani S AU - Arimitsu Y AU - Akama K TI - Antibody activities of immunoglobulins in anti-leptospiral horse sera. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/*analysis MH - Complement Fixation Tests MH - Female MH - Fractionation MH - Guinea Pigs MH - Horses/immunology MH - Immunoglobulins/*immunology MH - Leptospira/*immunology MH - Leptospirosis/prevention & control MH - Support, Non-U.S. Gov't RN - 0 (Antibodies) PT - JOURNAL ARTICLE DA - 820107 DP - 1980 Oct IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 239-47 SB - M CY - JAPAN IP - 5 VI - 33 JC - KLZ AA - Author EM - 8203 AB - Antileptospiral sera from hyperimmunized horses were fractionated by gel filtration on Sephadex G-200 or by starch block electrophoresis. The fractions were examined quantitatively for leptospiricidal, agglutinating and complement fixing activities. The leptospiricidal activity was higher in the 78 globulin fraction than in the 19S globulin fraction, while the agglutinating activity was shared by both the fractions being higher in the 19S fraction. Complement fixing activity was found evenly in both the fractions. Leptospiricidal and complement fixing activities were higher in gamma-globulin than in T- globulin, while the agglutinating activity was comparable in the two globulin fractions. That is, the agglutinating activity may not always behave along with the leptospiricidal activity. The results were discussed in connection with the therapeutic antiserum product for human use. PMID- 7300036 CU - 91 SO - Jpn J Med Sci Biol 1980 Oct;33(5):239-47 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 81183783 AU - Holroyd RG TI - Leptospira interrogans serovar hardjo vaccination of pregnant beef cows and subsequent growth rate of progeny. LA - Eng MH - Animal MH - Cattle/*growth & development/immunology/physiology MH - Comparative Study MH - Female MH - Leptospira/*immunology MH - Male MH - Pregnancy MH - *Pregnancy, Animal MH - Support, Non-U.S. Gov't MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 810623 DP - 1980 Oct IS - 0005-0423 TA - Aust Vet J PG - 481-3 SB - M CY - AUSTRALIA IP - 10 VI - 56 JC - 9IE AA - Author EM - 8108 AB - Five experiments with Leptospira interrogans serovar hardjo vaccine were carried out over a 6-year period in pregnant Brahman-cross and Sahiwal-cross cows in the dry tropics on northern Queensland. The numbers ranged from 127 breeders aged 2 to 5 years in 1972 to 344 breeders aged 2 to 9 years in 1977. Half of the cows were vaccinated twice in mid-pregnancy except for 1977, when they were vaccinated once. In 1975-1977 inclusive, half of the heifers were given an additional dose of vaccine at commencement of mating. Vaccination caused a significant (P less than 0.01) reduction of prenatal loss but not of perinatal or postnatal losses. Growth rates of calves from vaccinated and unvaccinated dams were similar. PMID- 7225005 SO - Aust Vet J 1980 Oct;56(10):481-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 81182152 AU - Thiermann AB TI - Canine leptospirosis in Detroit. LA - Eng MH - Administration, Oral MH - Animal MH - Bacteriuria MH - Bicarbonates/administration & dosage MH - Dog Diseases/*epidemiology MH - Dogs MH - Hamsters MH - Hydrogen-Ion Concentration MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Michigan RN - 0 (Bicarbonates) PT - JOURNAL ARTICLE DA - 810623 DP - 1980 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1659-61 SB - M CY - UNITED STATES IP - 10 VI - 41 JC - 40C AA - Author EM - 8108 AB - Among 433 stray dogs in Detroit, Michigan, surveyed for leptospiral agglutinins, 164 (37.8%) had significant titers to 1 or more leptospiral serotypes; from 123 suburban stray dogs tested, 23 (18.7%) had significant titers. The use of 2-mercaptoethanol on positive serum samples was helpful in identifying acute from chronic phase titers. Cross-reaction patterns also were clarified by the use of 2- mercaptoethanol. Cultural isolation of leptospires from dog urine was unsuccessful unless the urine had a pH from 6.6 to 8.0. Oral administration of sodium bicarbonate to alkalinize dog's urine resulted in the isolation of leptospires from dogs usually voiding acidic urine. Leptospira icterohaemorrhagiae was the most common serotype in this dog population by serologic techniques and was the only one isolated in culture. PMID- 7224293 CU - 91 SO - Am J Vet Res 1980 Oct;41(10):1659-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 81182151 AU - Thiermann AB TI - Effect of cyclophosphamide treatment on clinical and serologic response of rats to infection with Leptospira interrogans serovar icterohaemorrhagiae. LA - Eng MH - Animal MH - Bacteriuria MH - Brain/microbiology MH - Cyclophosphamide/*pharmacology MH - Hamsters MH - Immunosuppression MH - Kidney/microbiology MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/etiology/*immunology MH - Male MH - Rats MH - Septicemia MH - Weil's Disease/immunology RN - 50-18-0 (Cyclophosphamide) PT - JOURNAL ARTICLE DA - 810623 DP - 1980 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1655-8 SB - M CY - UNITED STATES IP - 10 VI - 41 JC - 40C AA - Author EM - 8108 AB - Young albino rats were immunosuppressed with cyclophosphamide and exposed to virulent and low-virulence Leptospira interrogans serovar icterohaemorrhagiae 820K. In rats exposed to virulent and low virulence leptospires, microscopic agglutinating antibody responses occurred later, and longer leptospiremic phase and more massive tissue invasion by the organisms were observed in immunosuppressed rats than in immunocompetent controls. Clinical and pathologic signs of illness were more severe in the immunosuppressed animals than in immunocompetent controls. When exposed to low-virulence leptospires, immunosuppressed rats became infected and developed signs of illness and 2 of 16 died. Immunocompetent rats rapidly developed a humoral response and did not develop any signs of illness, and with 1 exception, organisms were not recovered from any tissues. PMID- 7224292 SO - Am J Vet Res 1980 Oct;41(10):1655-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 81124018 AU - Adler B AU - Faine S AU - Muller HK AU - Green DE TI - Maturation of humoral immune response determines the susceptibility of guinea-pigs to leptospirosis. LA - Eng MH - *Aging MH - Animal MH - Antibody Formation MH - B-Lymphocytes/cytology MH - Body Weight MH - Female MH - Guinea Pigs MH - *Immunity, Cellular MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology MH - Lymph Nodes/cytology MH - Male MH - Phagocytosis MH - Spleen/cytology MH - Support, Non-U.S. Gov't MH - T-Lymphocytes/cytology PT - JOURNAL ARTICLE DA - 810413 DP - 1980 Oct IS - 0031-3025 TA - Pathology PG - 529-38 SB - M CY - AUSTRALIA IP - 4 VI - 12 JC - OTA AA - Author EM - 8106 AB - Baby guinea-pigs were susceptible to infection with Leptospira interrogans serovar pomona, but rapidly became resistant as they matured. Increased resistance with increasing weight of guinea-pigs was correlated with the development of ability to produce agglutinating antibodies to leptospires and with maturation of B-cell dependent (but not T-cell dependent) areas in lymphoid organs. These observations can explain the basis of species-resistance of adult guinea-pigs to infection with serovar pomona. PMID- 6970358 CU - 89 SO - Pathology 1980 Oct;12(4):529-38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81053630 AU - Estavoyer JM AU - Marquelet D AU - Baufle GH AU - Becque O AU - Michel-Briand Y AU - Pageaut G TI - [Severe leptospirosis with cardiac localization (letter)] LA - Fre MH - Case Report MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Myocardial Diseases/*etiology PT - LETTER DA - 810116 DP - 1980 Sep 27 IS - 0301-1518 TA - Nouv Presse Med PG - 2579 SB - M CY - FRANCE IP - 35 VI - 9 JC - O5Q EM - 8103 PMID- 7433045 CU - 91 TT - Leptospirose grave avec localisation cardique. SO - Nouv Presse Med 1980 Sep 27;9(35):2579 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81154827 AU - Higgins RJ AU - Harbourne JF AU - Little TW AU - Stevens AE TI - Mastitis and abortion in dairy cattle associated with Leptospira of the serotype hardjo. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Cattle MH - Cattle Diseases/*etiology/microbiology MH - Female MH - Leptospira/isolation & purification MH - Leptospirosis/complications/microbiology/*veterinary MH - Mastitis, Bovine/*etiology/microbiology MH - Milk/microbiology MH - Pregnancy PT - JOURNAL ARTICLE DA - 810513 DP - 1980 Sep 27 IS - 0042-4900 TA - Vet Rec PG - 307-10 SB - M CY - ENGLAND IP - 13 VI - 107 JC - XBS AA - Author EM - 8107 AB - Following a sudden drop in milk yield in a large dairy herd, leptospiral mastitis due to serotype hardjo was diagnosed serologically and by isolation of the organism from the milk and urine of affected cows. Two milkers subsequently became ill and developed titres to the Hebdomadis serogroup. During the same period the neighbouring herd experienced poor milking performance and a series of abortions and serological evidence suggested recent hardjo infection. The common source of infection appeared to be infected down calving heifers. PMID- 7210429 SO - Vet Rec 1980 Sep 27;107(13):307-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 81081201 AU - Toppich E AU - Kruger W TI - [Zooanthroponoses as occupational diseases] LA - Ger MH - Animal MH - Brucellosis/epidemiology MH - Dermatomycoses/epidemiology MH - Germany, East MH - Human MH - Insurance, Health MH - Leptospirosis/epidemiology MH - Occupational Diseases/*epidemiology MH - Ornithosis/epidemiology MH - Registries MH - Tuberculosis/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 810226 DP - 1980 Sep 1 IS - 0044-2178 TA - Z Arztl Fortbild (Jena) PG - 820-4 SB - M CY - GERMANY, EAST IP - 17 VI - 74 JC - XS6 EM - 8104 PMID- 7445569 CU - 88 TT - Zooanthroponosen als Berufskrankheiten. SO - Z Arztl Fortbild (Jena) 1980 Sep 1;74(17):820-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81064246 AU - Kingscote B TI - Isolation of a hamster-lethal strain of Leptospira hardjo [letter] LA - Eng MH - Animal MH - Hamsters MH - Leptospira/*isolation & purification/pathogenicity MH - Rodent Diseases/microbiology PT - LETTER DA - 810224 DP - 1980 Sep IS - 0008-5286 TA - Can Vet J PG - 266 CY - CANADA IP - 9 VI - 21 JC - CLS EM - 8104 PMID- 7438010 CU - 91 SO - Can Vet J 1980 Sep;21(9):266 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81047403 AU - Frerichs GN AU - Maley AD TI - Pseudoleptospires in blood culture [letter] LA - Eng MH - Animal MH - Blood/*microbiology MH - Chickens MH - Guinea Pigs MH - Hamsters MH - Human MH - *Leptospira MH - Leptospirosis/diagnosis MH - Mice MH - Microscopy PT - LETTER DA - 810116 DP - 1980 Sep IS - 0021-9746 TA - J Clin Pathol PG - 905-6 SB - A SB - M CY - ENGLAND IP - 9 VI - 33 JC - HT3 EM - 8103 PMID- 7430409 CU - 91 SO - J Clin Pathol 1980 Sep;33(9):905-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 81154432 AU - Manev C AU - Yaneva V AU - Yanakieva M AU - Uzunov G TI - A natural focus of infection with leptospires of the serovar lora in Bulgaria. LA - Eng MH - Animal MH - Bulgaria MH - Disease Reservoirs MH - Insectivora/*microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Mice MH - Rats MH - Rodent Diseases/*microbiology MH - Rodentia PT - JOURNAL ARTICLE DA - 810513 DP - 1980 Sep IS - 0041-3232 TA - Trop Geogr Med PG - 256-8 SB - M CY - NETHERLANDS IP - 3 VI - 32 JC - WGJ AA - Author EM - 8107 AB - A natural focus of infection with leptospira serovar lora (Australis serogroup) was discovered in the Tundga River Valley, South Bulgaria. 1 672 micromammals belonging to seven species were investigated. Serologically and bacteriologically a high incidence of infection was established. PMID- 7210161 SO - Trop Geogr Med 1980 Sep;32(3):256-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81152423 AU - Santa-Rosa CA AU - Lacaz C da S AU - Machado P de A AU - Yanaguita RM AU - Castrillon AL AU - Ferraroni JJ AU - Fonseca OJ TI - [Leptospirosis in Amazonas State. Serological survey] LA - Por MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Agglutination Tests MH - Brazil MH - English Abstract MH - Female MH - Human MH - Leptospirosis/epidemiology/*microbiology MH - Male MH - Middle Age MH - *Serotyping MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 810513 DP - 1980 Sep-Oct IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 265-8 CY - BRAZIL IP - 5 VI - 22 JC - S9D EM - 8107 PMID- 7209278 CU - 88 TT - Leptospirose no Estado do Amazonas: inquerito sorologico. EA - A SO - Rev Inst Med Trop Sao Paulo 1980 Sep-Oct;22(5):265-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 81099714 AU - Mackintosh CG AU - Marshall RB AU - Broughton ES TI - The use of a hardjo-pomona vaccine to prevent leptospiruria in cattle exposed to natural challenge with Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - Cattle/*immunology MH - Female MH - Leptospirosis/*immunology/prevention & control MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 810324 DP - 1980 Sep IS - 0048-0169 TA - N Z Vet J PG - 174-7 CY - NEW ZEALAND IP - 9 VI - 28 JC - OBZ EM - 8105 PMID- 6935554 CU - 88 SO - N Z Vet J 1980 Sep;28(9):174-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 81043407 AU - Liu XM AU - Ruan XZ AU - Cai Z AU - Yu BR AU - He SP AU - Gong YH TI - Moyamoya disease caused by leptospiral cerebral arteritis. LA - Eng MH - Adolescence MH - Adult MH - Arterial Occlusive Diseases/*etiology MH - Arteritis/*complications MH - Cerebral Angiography MH - Cerebral Artery Diseases/*complications MH - Child MH - Child, Preschool MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Moyamoya Disease/*etiology/pathology PT - JOURNAL ARTICLE DA - 810126 DP - 1980 Sep IS - 0366-6999 TA - Chin Med J (Engl) PG - 599-604 CY - CHINA IP - 9 VI - 93 JC - D3B EM - 8103 PMID- 6775894 CU - 91 SO - Chin Med J (Engl) 1980 Sep;93(9):599-604 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [72 medline neighbors] UI - 81084299 AU - Sapp WJ AU - Siddique IH AU - Williams CS AU - Graham T TI - Histopathologic evaluation of livers of pregnant hamsters infected with Leptospira canicola. LA - Eng MH - Animal MH - Female MH - *Hamsters MH - Leptospirosis/pathology/*veterinary MH - Liver/*ultrastructure MH - Microscopy, Electron MH - Pregnancy MH - Pregnancy Complications, Infectious/pathology/*veterinary MH - Rodent Diseases/*pathology MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 810219 DP - 1980 Aug IS - 0002-9645 TA - Am J Vet Res PG - 1288-92 SB - M CY - UNITED STATES IP - 8 VI - 41 JC - 40C AA - Author EM - 8104 AB - Pregnant hamsters were inoculated with Leptospira canicola by an intraperitoneal route. Grossly, the livers were enlarged and pale yellow. On light microscopic examination, disruption of the hepatic cords, as well as granulation of hepatocyte cytoplasm, was evident. On electron microscopic examination, the livers had evidence of severe cellular degradation as early as post-inoculation hour (PIH) 24. At PIH 96, pathologic changes were more pronounced. The rough endoplasmic reticulum was swollen and there was membrane disruption. These changes were not observed in the livers of control animals. In addition, livers of the fetuses at PIH 72 exhibited severe degenerative changes. PMID- 7447125 SO - Am J Vet Res 1980 Aug;41(8):1288-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 81035642 AU - Shimono E AU - Yanagawa R AU - Barranca GT TI - Isolation of revertants from antigenic variants of leptospiras. LA - Eng MH - Animal MH - *Antigens, Bacterial/genetics MH - Culture Media MH - Immune Sera MH - Leptospira interrogans/growth & development/genetics/*immunology MH - Mice MH - Phenotype MH - Precipitin Tests MH - Rabbits/immunology MH - *Variation (Genetics) RN - 0 (Antigens, Bacterial) RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 801218 DP - 1980 Aug IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 392-9 SB - M CY - GERMANY, WEST IP - 3 VI - 247 JC - Y5P AA - Author EM - 8102 AB - The revertants were isolated from the antigenic variants of Leptospira interrogans serovar copenhageni Shibaura by plating the variants on the solid medium containing the homologous immune serum, and by noting the growth of small colonies. The revertants which produced the small colonies were antigenically identical with the parents. The variants which retained their antigenicity for 2 to 3 years produced only a small number of revertants. On the other hand, the variants which phenotypically changed to the parent during the same period of maintenance produced many revertants. The revertant-clones and the variant-clones showed a similar generation time. No revertant was isolated from the variants of hebdomadis Hebdomadis. PMID- 7424250 CU - 91 SO - Zentralbl Bakteriol [A] 1980 Aug;247(3):392-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81010455 AU - Seidman CE AU - Murphy PA TI - Leptospirosis. LA - Eng MH - Acute Disease MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Hepatitis, Alcoholic/diagnosis MH - Hepatitis, Viral, Human/diagnosis MH - Human MH - Leptospirosis/*diagnosis/microbiology MH - Male PT - JOURNAL ARTICLE DA - 801124 DP - 1980 Aug IS - 0021-7263 TA - Johns Hopkins Med J PG - 65-9 SB - M CY - UNITED STATES IP - 2 VI - 147 JC - KS9 EM - 8101 PMID- 7412068 SO - Johns Hopkins Med J 1980 Aug;147(2):65-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 81009512 AU - Hathaway SC AU - Marshall RB TI - Haemolysis as a means of distinguishing between Leptospira interrogans serovars balcanica and hardjo. LA - Eng MH - Animal MH - Cattle MH - *Hemolysis MH - Human MH - Leptospira interrogans/*classification MH - Opossums MH - Serotyping MH - Sheep PT - JOURNAL ARTICLE DA - 801120 DP - 1980 Aug IS - 0022-2615 TA - J Med Microbiol PG - 477-81 SB - M CY - ENGLAND IP - 3 VI - 13 JC - J2N AA - Author EM - 8101 AB - Leptospira interrogans serovar balcanica was haemolytic for washed human, cattle, sheep and possum red blood cells (RBC); serovar hardjo was non-haemolytic. A test for haemolysis may prove useful in the preliminary differentiation of balcanica and hardjo isolates. Balcanica was non-haemolytic for unwashed RBC from human and bovine donors whose serum contained Hebdomadis serogroup antibody. Haemolytic activity tended to disappear with repeated subculture of balcanica. PMID- 7411589 SO - J Med Microbiol 1980 Aug;13(3):477-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 81192227 AU - Brooks JB AU - Edman DC AU - Alley CC AU - Craven RB AU - Girgis NI TI - Frequency-pulsed electron capture gas-liquid chromatography and the tryptophan color test for rapid diagnosis of tuberculous and other forms of lymphocytic meningitis. LA - Eng MH - Cerebrospinal Fluid/analysis MH - Chromatography, Gas/*methods MH - Human MH - *Indicators and Reagents MH - Meningitis/*diagnosis MH - Support, U.S. Gov't, Non-P.H.S. MH - Tryptophan/analysis MH - Tuberculosis, Meningeal/*diagnosis RN - 0 (Indicators and Reagents) RN - 6912-86-3 (Tryptophan) PT - JOURNAL ARTICLE DA - 810709 DP - 1980 Aug IS - 0095-1137 TA - J Clin Microbiol PG - 208-15 SB - M CY - UNITED STATES IP - 2 VI - 12 JC - HSH AA - Author EM - 8109 AB - A total of 260 samples of cerebrospinal fluid received from Egypt, the United States, Canada, and South America were examined by frequency- pulsed electron capture gas-liquid chromatography (FPEC-GLC) for tuberculous and other forms of lymphocytic meningitis. Thirty-four of the specimens were culture positive for M. tuberculosis, and four cerebrospinal fluid specimens of herpes meningitis were established by immunological techniques. The compound, 3-(2'-ketohexyl)-indoline, was found in about 60% of the Egyptian tuberculous specimens and none of the culture-positive American specimens. the carboxylic and hydroxy acid FPEC-GLC profiles were used effectively in conjunction with other clinical data to make the diagnosis even in the absence of 3-(2'- ketohexyl)indoline. Herpes meningitis and mixed infections of Myeobacterium tuberculosis-herpes, M. tuberculosis-leptospira, and M. tuberculosis-Haemophilus influenzae produced profiles different from each other and from pure culture cases. The color test for tuberculous meningitis was evaluated, and free tryptophan was eliminated as the source of color reaction. Indications are that 3-(2'- ketohexyl)indoline, in most cases, is not responsible for the positive color reaction. Differences in the clinical and FPEC-GLC data obtained from samples from different geographical regions are discussed. PMID- 7229007 CU - 91 SO - J Clin Microbiol 1980 Aug;12(2):208-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 81171009 AU - Arimitsu Y AU - Mori M AU - Akama K TI - Cross antigenicities of Leptospira interrogans serovar copenhageni Shibaura strain for preparing biological products in Japan. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial/immunology MH - Cross Reactions MH - Guinea Pigs MH - Immune Sera/*immunology MH - Japan MH - Leptospira interrogans/*immunology MH - Rabbits RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 810623 DP - 1980 Aug IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 223-9 SB - M CY - JAPAN IP - 4 VI - 33 JC - KLZ AA - Author EM - 8108 AB - Cross protective antigenicities of Leptospira were studied with 16 antisera to 13 serovars of Leptospira interrogans and a virulent strains "Shibaura (V)", which is now considered to belong to serovar copenhageni, for challenge. The antisera of the rabbits highly immunized with various serovar live antigens were examined for leptospiricidal activity; cross immunity was recognized only in the same serogroup, Icterohaemorrhagiae. Serovar icterohaemorrhagiae lacks a prt of the antigenic components of copenhageni, but the antiserum to the former showed potent leptospiricidal activity to Shibaura (V). Anti- copenhageni immune serum absorbed with the icterohaemorrhagiae antigen did not show any protective activity to Shibaura (V). PMID- 7218577 CU - 91 SO - Jpn J Med Sci Biol 1980 Aug;33(4):223-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 81035643 AU - Terpstra WJ AU - Ligthart GS AU - Schoone GJ TI - Serodiagnosis of human leptospirosis by enzyme-linked-immunosorrbent- assay (ELISA). LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - Comparative Study MH - *Enzyme-Linked Immunosorbent Assay MH - Human MH - *Immunoenzyme Techniques MH - Leptospirosis/*diagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 801218 DP - 1980 Aug IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 400-5 SB - M CY - GERMANY, WEST IP - 3 VI - 247 JC - Y5P AA - Author EM - 8102 AB - An enzyme-linked-immunosorbent-assay (ELISA) is described for the serodiagnosis of leptospirosis. Using an antigen prepared from a heated culture of a single leptospira strain (Wijnberg) the ELISA is a genusspecific test. The microscopic agglutination test (MAT) served as a reference. ELISA and MAT results agreed in 95% of the sera from 96 leptospirosis patients. One false positive was found in 217 controls. The ELISA is sensitive, specific and relatively easy to perform. PMID- 6999805 CU - 91 SO - Zentralbl Bakteriol [A] 1980 Aug;247(3):400-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 81149648 AU - Bahaman AR AU - Marshall RB AU - Blackmore DK AU - Hathaway SW TI - Isolation of Leptospira interrogans serovar hardjo from sheep in New Zealand [letter] LA - Eng MH - Animal MH - Leptospira interrogans/*isolation & purification MH - New Zealand MH - Sheep/microbiology MH - Sheep Diseases/*microbiology MH - Weil's Disease/microbiology/*veterinary PT - LETTER DA - 810528 DP - 1980 Aug IS - 0048-0169 TA - N Z Vet J PG - 1980 CY - NEW ZEALAND IP - 8 VI - 28 JC - OBZ EM - 8107 PMID- 6937814 CU - 91 SO - N Z Vet J 1980 Aug;28(8):1980 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 81149647 AU - Mackintosh CG AU - Marshall RB TI - Serological titres resulting from leptospiral vaccine [letter] LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Bacterial Vaccines/*immunology MH - Cattle/*immunology MH - Leptospira interrogans/*immunology MH - Vaccination/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - LETTER DA - 810528 DP - 1980 Aug IS - 0048-0169 TA - N Z Vet J PG - 172 CY - NEW ZEALAND IP - 8 VI - 28 JC - OBZ EM - 8107 PMID- 6937813 CU - 91 SO - N Z Vet J 1980 Aug;28(8):172 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81143636 AU - Ishimaru M TI - [Studies of application of indirect fluorescent antibody technique for serodiagnosis of leptospirosis. 2. Experimental studies on sera from patients and stray dogs (author's transl)] LA - Jpn MH - Animal MH - Antibodies, Bacterial/analysis MH - Dog Diseases/*diagnosis MH - Dogs MH - English Abstract MH - Evaluation Studies MH - Fluorescent Antibody Technique/*methods MH - Human MH - Leptospirosis/*diagnosis/veterinary MH - Serodiagnosis/methods RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810521 DP - 1980 Aug IS - 0387-5911 TA - Kansenshogaku Zasshi PG - 374-82 CY - JAPAN IP - 8 VI - 54 JC - IJR EM - 8107 PMID- 6782176 CU - 91 EA - A SO - Kansenshogaku Zasshi 1980 Aug;54(8):374-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81143635 AU - Ishimaru M TI - [Studies of application of indirect fluorescent antibody technique for serodiagnosis of leptospirosis. 1. Basal experiments with immune rabbit sera (author's transl)] LA - Jpn MH - Animal MH - Antibodies, Bacterial/analysis MH - English Abstract MH - Female MH - Fluorescent Antibody Technique/*methods MH - Guinea Pigs MH - Immune Sera MH - Leptospirosis/*diagnosis MH - Mice MH - Rabbits/immunology MH - Serodiagnosis/methods RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810521 DP - 1980 Aug IS - 0387-5911 TA - Kansenshogaku Zasshi PG - 365-73 CY - JAPAN IP - 8 VI - 54 JC - IJR EM - 8107 PMID- 6782175 CU - 91 EA - A SO - Kansenshogaku Zasshi 1980 Aug;54(8):365-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 81137436 AU - Xu ZX TI - [Roentgenographic manifestations of diffuse pulmonary hemorrhage in leptospirosis (report of 50 cases) (author's transl)] LA - Chi MH - Adolescence MH - Adult MH - Animal MH - Case Report MH - Female MH - Guinea Pigs MH - Hemorrhage/*radiography MH - Human MH - Leptospirosis/pathology/*radiography MH - Lung/pathology MH - Lung Diseases/*radiography PT - JOURNAL ARTICLE DA - 810526 DP - 1980 Aug IS - 0529-5661 TA - Chung Hua Fang She Hsueh Tsa Chih PG - 188-90 CY - CHINA IP - 3 VI - 14 JC - D7D EM - 8107 RO - M:MYA PMID- 6451405 LR - 821014 CU - 92 SO - Chung Hua Fang She Hsueh Tsa Chih 1980 Aug;14(3):188-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81062248 AU - Gordon LM TI - Isolation of Leptospira interrogans serovar Hardjo from sheep [letter] LA - Eng MH - Animal MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Male MH - Sheep MH - Sheep Diseases/*microbiology PT - LETTER DA - 810126 DP - 1980 Jul IS - 0005-0423 TA - Aust Vet J PG - 348-9 SB - M CY - AUSTRALIA IP - 7 VI - 56 JC - 9IE EM - 8103 PMID- 7436944 CU - 91 SO - Aust Vet J 1980 Jul;56(7):348-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 81062242 AU - Milner AR AU - Wilks CR AU - Calvert K TI - The prevalence of antibodies to members of Leptospira interrogans in cattle. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Australia MH - Cattle MH - Cattle Diseases/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/*veterinary MH - Species Specificity MH - Support, Non-U.S. Gov't RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810126 DP - 1980 Jul IS - 0005-0423 TA - Aust Vet J PG - 327-30 SB - M CY - AUSTRALIA IP - 7 VI - 56 JC - 9IE AA - Author EM - 8103 AB - A total of 1,355 random samples taken from bovine serums submitted for brucellosis testing in Victoria were submitted to the microscopic agglutination test for the presence of antibody to 12 serovars of Leptospira interrogans. The most common reaction obtained was to serovar hardjo, although the percentage of reactors varied from 24.8% in the metropolitan area to 56.3% in north-eastern Victoria (mean 40.6%). A total of 86.3% of farms from which 3 or more samples were taken had at least one reactor to serovar hardjo. The prevalence of antibody to other serovars was tarassovi (7.8% of reactors), ballum (3.7%), pomona (2.4%), autumnalis (1.8%) and bataviae (1.2%). Reactions to other serovars were observed in serums of less than 1% of cattle tested; serums from 50.8% of cattle did not react to any antigen. PMID- 7436939 CU - 91 SO - Aust Vet J 1980 Jul;56(7):327-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 81060535 AU - Tripathy DN AU - Hanson LE AU - Jones FC 3d TI - Growth of hebdomadis group of leptospires in solid medium. LA - Eng MH - Comparative Study MH - Culture Media MH - Leptospira/cytology/*growth & development MH - Support, Non-U.S. Gov't RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 810116 DP - 1980 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1153-4 SB - M CY - UNITED STATES IP - 7 VI - 41 JC - 40C AA - Author EM - 8103 AB - Leptospira hardjo, szwajizak, and sejroe produced colonial growth in bovine albumin polysorbate 80 (BAP80) solid medium which had been supplemented either with sodium pyruvate (100 micrograms/ml) or with 5% rabbit serum. Leptospira hardjo produced two morphologic types of colonies in both supplemented media. Growth did not occur with any of the three serovars in the unsupplemented BAP80 medium. These results indicate that addition of either rabbit serum or sodium pyruvate would aid in promoting growth of some fastidious leptospires. PMID- 7436114 CU - 91 SO - Am J Vet Res 1980 Jul;41(7):1153-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81052007 AU - Morter RL TI - Serology in cattle vaccinated with leptospirosis bacterins. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - *Bacterial Vaccines MH - Cattle/*immunology MH - Leptospira/*immunology MH - Vaccination/*veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 810126 DP - 1980 Jul IS - 0362-8140 TA - Mod Vet Pract PG - 611, 614 SB - M CY - UNITED STATES IP - 7 VI - 61 JC - NGO EM - 8103 PMID- 7432343 CU - 91 SO - Mod Vet Pract 1980 Jul;61(7):611, 614 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 81041800 AU - Higgins R AU - Descoteaux JP AU - Degre R TI - Pathogenesis of experimental Leptospira interrogans serotype icterohaemorrhagiae infection in the guinea pigs: possible role of endotoxin of intestinal bacteria in the development of lesions. LA - Eng MH - Animal MH - Comparative Study MH - Endotoxins/analysis/*toxicity MH - Germ-Free Life MH - Guinea Pigs MH - Leptospira interrogans/isolation & purification/*pathogenicity MH - Leptospirosis/*etiology/microbiology/pathology MH - Limulus Test RN - 0 (Endotoxins) PT - JOURNAL ARTICLE DA - 810129 DP - 1980 Jul IS - 0008-4050 TA - Can J Comp Med PG - 304-8 SB - M CY - CANADA IP - 3 VI - 44 JC - CI0 AA - Author EM - 8103 AB - Germ-free guinea pigs were infected with a virulent strain of Leptospira interrogans serotype icterohaemorrhagiae to evaluate the possible role of endotoxin of intestinal bacteria in the development of hemorrhages and hepatic and renal failure. Clinical manifestations, necropsy findings and histological lesions were similar to those seen in control animals. In the second part of the experiment, endotoxin was not detected by the Limulus test in the blood of ten guinea pigs during the five day course of leptospirosis. PMID- 7427777 CU - 91 SO - Can J Comp Med 1980 Jul;44(3):304-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 81026664 AU - Rubin SJ AU - Perlman S AU - Ellinghausen HC Jr TI - Isolation of Leptospira biflexa from commercially prepared deionized water labeled "sterile for tissue culture". LA - Eng MH - Adult MH - Aged MH - *Culture Media MH - Diagnostic Errors MH - Human MH - Leptospira/*isolation & purification MH - Leptospira interrogans/classification MH - Leptospirosis/diagnosis MH - Male MH - Middle Age MH - Urine/microbiology MH - *Water Microbiology MH - Water Pollution RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 801216 DP - 1980 Jul IS - 0095-1137 TA - J Clin Microbiol PG - 121-3 SB - M CY - UNITED STATES IP - 1 VI - 12 JC - HSH AA - Author EM - 8102 AB - Leptospira biflexa were isolated from urine cultures of two patients with clinical and laboratory findings compatible with leptospirosis. Neither patient had detectable leptospiral agglutinins. The source of the L. biflexa was water labeled " "sterile for tissue culture" purchased from M. A. Bioproducts, formerly Microbological Associates. M. A. Bioproducts water is sterilized by filtration through a 0.22-mum- pore size membrane filter. Leptospiral contamination can occur in products sterilized by filtration. Heat sterilization of water eliminates this possibility. PMID- 7419696 CU - 91 SO - J Clin Microbiol 1980 Jul;12(1):121-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [27 medline neighbors] UI - 81009843 AU - Binninger CE AU - Beecham JJ AU - Thomas LA AU - Winward LD TI - A serologic survey for selected infectious diseases of black bears in Idaho. LA - Eng MH - Animal MH - Antibodies/*blood MH - Bacterial Infections/blood/*veterinary MH - *Bears MH - *Carnivora MH - Idaho RN - 0 (Antibodies) PT - JOURNAL ARTICLE DA - 801125 DP - 1980 Jul IS - 0090-3558 TA - J Wildl Dis PG - 423-30 SB - M CY - UNITED STATES IP - 3 VI - 16 JC - KEM AA - Author EM - 8101 AB - Two hundred sixty-five black bears (Ursus americanus) from northcentral Idaho were examined serologically over a five-year period for antibodies against selected infectious disease agents. The number of positive serum samples number of sera tested and percent positive for each infectious agent is: tularemia, 65/340 (19); brucellosis, 18/332 (5); toxoplasmosis, 23/303 (8); leptospirosis, 2/196 (1); trichinosis, 16/122 (13); Q-fever, 13/210 (6); St. Louis encephalitis, 3/340 (1); western equine encephalitis, 4/334 (1); Rocky Mountain Spotted Fever, 6/282 (2). Black bears may serve as an indicator for infection in other wildlife, domestic animals and humans in the area.. PMID- 7411749 CU - 91 SO - J Wildl Dis 1980 Jul;16(3):423-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81009826 AU - Redetzke KA AU - McCann MJ TI - Isolation of Leptospira from desert rodents of west Texas. LA - Eng MH - Animal MH - Blood Chemical Analysis MH - Leptospira/analysis/*isolation & purification MH - Leptospirosis/*veterinary MH - *Rodentia MH - Texas MH - Urine/analysis PT - JOURNAL ARTICLE DA - 801125 DP - 1980 Jul IS - 0090-3558 TA - J Wildl Dis PG - 333-7 SB - M CY - UNITED STATES IP - 3 VI - 16 JC - KEM AA - Author EM - 8101 AB - Urine, blood and tissue samples from 369 rodents of 13 species were cultured for Leptospira. Four serogroups, including ballum, isterohaemorrhagiae, pomona, and grippotyphosa, were isolated from 70 rodents (19%) of 9 species. PMID- 7411737 SO - J Wildl Dis 1980 Jul;16(3):333-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 81231612 AU - Nicolescu M TI - Serovar determination of Romanian L. icterohaemorrhagiae strains. LA - Eng MH - Animal MH - Human MH - Leptospira interrogans/classification/*isolation & purification MH - Leptospirosis/*diagnosis MH - Rats MH - Romania MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 810820 DP - 1980 Jul-Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 213-9 CY - ROMANIA IP - 3 VI - 39 JC - 8EM EM - 8110 PMID- 7247665 SO - Arch Roum Pathol Exp Microbiol 1980 Jul-Sep;39(3):213-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 80255001 AU - Cucinell SA TI - Early diagnosis and treatment of leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Erythromycin/*therapeutic use MH - Human MH - Leptospirosis/*diagnosis/drug therapy MH - Male MH - Middle Age MH - Panama MH - Support, U.S. Gov't, Non-P.H.S. RN - 114-07-8 (Erythromycin) PT - JOURNAL ARTICLE DA - 801024 DP - 1980 Jul IS - 0026-4075 TA - Mil Med PG - 495-7 CY - UNITED STATES IP - 7 VI - 145 JC - N1A EM - 8012 PMID- 6772994 CU - 91 SO - Mil Med 1980 Jul;145(7):495-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81026682 AU - Adler B AU - Faine S AU - Yanagawa R TI - Comparative studies on two antigens (F4 and TM) extracted from leptospires. LA - Eng MH - Absorption MH - Animal MH - Antigens, Bacterial/*analysis MH - Comparative Study MH - Cross Reactions MH - Epitopes MH - Hemagglutination Inhibition Tests MH - Hemagglutination Tests MH - Immune Sera MH - Immunodiffusion MH - Leptospira interrogans/*immunology MH - Rabbits/immunology MH - Support, Non-U.S. Gov't RN - 0 (Antigens, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 801216 DP - 1980 Jul IS - 0095-1137 TA - J Clin Microbiol PG - 7-9 SB - M CY - UNITED STATES IP - 1 VI - 12 JC - HSH AA - Author EM - 8102 AB - F4 and TM antigens extracted from Leptospira interrogans serovars pomona, icterohaemorrhagiae, and copenhageni were compared by immunodiffusion, by hemagglutination inhibition, and by selective absorption of antisera. These data, together with previous information on the serological specificities of the two antigen preparations, suggest that F4 and TM are different antigens. PMID- 6158524 CU - 95 SO - J Clin Microbiol 1980 Jul;12(1):7-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 80254212 AU - Buckley B TI - Q fever epidemic in Victorian general practice. LA - Eng MH - *Abattoirs MH - Adolescence MH - Adult MH - Animal MH - Antibodies, Bacterial/analysis MH - Australia MH - Case Report MH - Complement Fixation Tests MH - Disease Outbreaks/*epidemiology MH - Goats/microbiology MH - Human MH - Male MH - Middle Age MH - Occupational Diseases/diagnosis/*epidemiology/transmission MH - Q Fever/diagnosis/*epidemiology/transmission RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 801027 DP - 1980 Jun 14 IS - 0025-729X TA - Med J Aust PG - 593-5 SB - M CY - AUSTRALIA IP - 12 VI - 1 JC - M26 AA - Author EM - 8012 AB - In 1979, 110 people associated with a local rural abattoir presented with an acute febrile illness thought to be Q fever. Of these, 70 were shown by serotesting to have had Q fever, and one was shown to have had leptospirosis alone. Four individuals had mixed infections of Q fever with another zoonotic infection, two with leptospirosis, and two with brucellosis. Only 44% of suspected cases of Q fever were shown to have complement-fixing antibodies to Q fever four weeks after the infection, but 74% had anti-bodies 12 weeks after infection. This epidemic of Q fever occurred soon after the abattoir began to slaughter feral goats for the first time; there is reason to believe that the epidemic may have been related to the introduction of this practice. PMID- 7402155 CU - 91 SO - Med J Aust 1980 Jun 14;1(12):593-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 80254211 AU - McKelvie P TI - Q fever in a Queensland meatworks. LA - Eng MH - *Abattoirs MH - Adolescence MH - Adult MH - Animal MH - Antibodies, Bacterial/analysis MH - Australia MH - Cattle/microbiology MH - Disease Outbreaks MH - Employment MH - Human MH - Middle Age MH - Occupational Diseases/*epidemiology/transmission MH - Q Fever/*epidemiology/transmission MH - Retrospective Studies MH - Sheep/microbiology MH - Swine/microbiology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 801027 DP - 1980 Jun 14 IS - 0025-729X TA - Med J Aust PG - 590-3 SB - M CY - AUSTRALIA IP - 12 VI - 1 JC - M26 AA - Author EM - 8012 AB - An epidemiological study of Q fever infection in a Brisbane meatworks was undertaken. A retrospective 10-year study (1968 to 1977) revealed an average annual incidence of 1% for the nine years excluding 1969, while an outbreak with a 7.9% incidence occurred in 1969. No seasonal distribution was found. Results indicated that cattle form the major source of Coxiella burneti (infectious agent of Q fever) in the meatworks and that the highest risk of infection exists on the cattle slaughter floor. The 1969 outbreak showed a departure from the average pattern of infection in that the highest incidences were recorded in small stock (sheep and swine) workers and non-meat handlers rather than in cattle slaughtermen. This suggested the importance of sheep and/or swine forming a source of the infection. Investigations into the factors contributing to the 1969 outbreak in this meatworks failed to reveal an; conclusive data. Inhalation of infectious dust and aerosols proved to be the major channel of transmission of infection rather than direct inoculation. A serological survey of 139 employees revealed 15.8% prevalence of complement-fixing antibodies to C. burneti, 0% to brucellosis, 0.7% to leptospirosis, and 0.7% to Toxoplasma gondii. Of those with positive titres for Q fever, nine of the 22 subjects did not recall any clinical illness. PMID- 7402154 CU - 91 SO - Med J Aust 1980 Jun 14;1(12):590-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81116520 AU - Thiermann AB AU - Frank RR TI - Human leptospirosis in Detroit and the role of rats as chronic carriers. LA - Eng MH - Animal MH - Case Report MH - *Disease Vectors MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/*etiology/veterinary MH - Male MH - Michigan MH - Middle Age MH - Occupational Diseases/diagnosis MH - Rats/*microbiology MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 810424 DP - 1980 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 62-72 SB - M CY - TAIWAN IP - 1 VI - 7 JC - GTK AA - Author EM - 8106 AB - Human leptospirosis was diagnosed in three patients from Detroit General Hospital. Epidemiological studies of these cases revealed heavy rat infestations in the residences of two of the patients. Leptospires serotype icterohaemorrhagiae were isolated from the rats and one of the patients. Cultural isolation was attempted from numerous blood and urine samples from each patient. Media containing different selective contaminant inhibitor substances was also utilized. Only two samples were culturally positive. It appears that very few viable cells are shed by human patients intermittently. Clinical reports and leptospirosis diagnosis are reported for each of the cases. The agglutinin-absortion test proved to be helpful in elucidating the true etiologic agent in the absence of cultural isolation. A serological survey for leptospirosis was conducted among swine slaughterhouse workers in Detroit. Significant titres to Leptospira pomona were observed. PMID- 7461920 SO - Int J Zoonoses 1980 Jun;7(1):62-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81116516 AU - Urquhart AE AU - Lee MG AU - King SD AU - Terry SI TI - Human leptospirosis infective serogroups and serotypes in Jamaica. LA - Eng MH - Female MH - Human MH - Jamaica MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/epidemiology/*microbiology MH - Male MH - Serodiagnosis MH - Serotyping MH - Time Factors PT - JOURNAL ARTICLE DA - 810424 DP - 1980 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 44-8 SB - M CY - TAIWAN IP - 1 VI - 7 JC - GTK AA - Author EM - 8106 AB - Of a total of 5,021 samples of sera tested in Jamaica between 1960- 1978, 651 (12.9%) were positive in significant to microscopic agglutination for leptospirosis. There were 50 (5.9%) positive isolates of 845 cultures. Six serogroups and 13 serotypes of pathogenic leptospiral strains were identified. The serogroup icterohaemorrhagiae serovar icterohaemorrhagiae accounted for 57% of infections and the serogroup hebdomadis, serovar jules accounting for 31% of cases. Human leptospirosis is grossly under-reported in Jamaica and only systematic surveys and surveillance can define the true incidence of the public health problem of this disease. PMID- 7461917 CU - 90 SO - Int J Zoonoses 1980 Jun;7(1):44-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 81116515 AU - Santa Rosa CA AU - Sulzer CR AU - Yanaguita RM AU - Da Silva AS TI - Leptospirosis in wildlife in Brazil: isolation of serovars canicola, pyrogenes and grippotyphosa. LA - Eng MH - Animal MH - Animals, Wild MH - Brazil MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Rats/*microbiology MH - Rodent Diseases/*microbiology MH - Serotyping MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 810424 DP - 1980 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 40-3 SB - M CY - TAIWAN IP - 1 VI - 7 JC - GTK AA - Author EM - 8106 AB - The isolation of serovar canicola from the Norway rat (Rattus norvegicus), shows that it is a reservoir of canicola and is therefore significant from an epidemiological point of view. The isolation of pyrogenes and grippotyphosa from a water rat, Nectomys squamipes is also described. PMID- 7461916 CU - 90 SO - Int J Zoonoses 1980 Jun;7(1):40-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [94 medline neighbors] UI - 81058414 AU - Schonberg A AU - Caldas EM AU - Sampaio MB AU - Costa E AU - Plank SJ TI - Leptospirin - an intradermic test for the diagnosis of leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals, Domestic MH - Antibodies, Bacterial/analysis MH - Bacterial Proteins/*diagnostic use MH - Brazil MH - Comparative Study MH - Human MH - *Intradermal Tests MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/veterinary MH - *Skin Tests RN - 0 (leptospirin) RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Proteins) PT - JOURNAL ARTICLE DA - 810116 DP - 1980 Jun IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 114-23 SB - M CY - GERMANY, WEST IP - 1 VI - 247 JC - Y5P AA - Author EM - 8103 AB - IN the State of Bahia (Brazil) the leptospirin produced in Germany for experimental use by the Institute for Veterinary Medicine, Federal Health Office, Berlin, was administered to humans and animals in order to diagnose leptospirosis in collaboration with this Institute. The results were compared with the microscopic agglutination reaction. The total number of test persons or animals was 268; this group included 81 human patients. 60 heads of cattle, 50 goats, 40 pigs, 25 horses, and 12 dogs. All were tested serologically and simultaneously the intracutaneous test was carried out. This test was positive when the erythema formed had a diameter of more than 9 mm. The evaluation took place 8 to 10 h and 24 h after the injection of leptospirin. 1. 52 humans reacted serologically; out of this group 44 were positive in the leptospirin test. The allergy test was also negative in the 29 serologically negative patients. 2. Out of the 21 heads of cattle with a positive agglutination test 7 reacted to leptospirin whereas 39 animals which did not react serologically were also negative in the skin test. 3. Although 10 goats out of 50 reacted serologically, all were negative in the intracutaneous test. 4. 9 out of 40 pigs reacted serologically; however, 8 reacted only to apathogenic leptospires (L.patoc, L.rufino, L.andamana). Out of these 9 animals 4 were positive in the intracutaneous test; among them the pig which reacted serologically to L.autumnalis. Out of 31 serologically negative pigs 2 were allergologically positive. 5. Out of 21 serologically positive horses 15 exhibited an erythema which was considered positive in the skin test. 4 serologically negative animals also were negative in the intracutaneous test. 6. Out of 6 serologically positive dogs, 4 reacted to leptospirin. 6 that had reacted serologically were all negative in the intracutaneous test. A comparison of the serological and allergological findings judged by the serological standard showed that out of all cases tested, 0.7% had at the same time a serologically negative and allergologically positive reaction and 16.8% had a serologically positive and allergologically negative reaction. In some cases, the administration of leptospirin caused the formation of antibodies which could only be detected in low dilutions and usually disappeared after 6-8 weeks. In humans, pigs, and horses the leptospirin also showed positive reactions which serologically could be attributed only to biflexa leptospires. Serotypes not contained in the leptospirin were accounted for to a varying degree in the individual animal species. These reactions and the results of other studies carried out in pig stocks have been the basis for studies performed at the Institute for Veterinary Medicine. These studies are expected to contribute to an improvement of the sensitivity of the leptospirin. PMID- 7434992 CU - 91 SO - Zentralbl Bakteriol [A] 1980 Jun;247(1):114-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 81010513 AU - Sitprija V AU - Pipatanagul V AU - Mertowidjojo K AU - Boonpucknavig V AU - Boonpucknavig S TI - Pathogenesis of renal disease in leptospirosis: Clinical and experimental studies. LA - Eng MH - Adult MH - Animal MH - Antigens, Bacterial MH - Disease Models, Animal MH - Female MH - Hamsters MH - Human MH - Kidney Diseases/*etiology/immunology/pathology MH - Leptospira interrogans MH - Leptospirosis/*complications/immunology/pathology MH - Male RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 801125 DP - 1980 Jun IS - 0085-2538 TA - Kidney Int PG - 827-36 SB - M CY - GERMANY, WEST IP - 6 VI - 17 JC - KVB EM - 8101 PMID- 7412114 CU - 91 SO - Kidney Int 1980 Jun;17(6):827-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [87 medline neighbors] UI - 80209680 AU - Amstutz HE TI - Cancer eye and infertility. LA - Eng MH - Animal MH - Bacterial Vaccines MH - Carcinoma, Squamous Cell/pathology/prevention & control/*veterinary MH - Cattle MH - Cattle Diseases/*etiology/pathology/prevention & control MH - Eye Neoplasms/prevention & control MH - Eyelid Neoplasms/pathology/*veterinary MH - Female MH - Infertility/etiology/veterinary MH - Leptospira/immunology MH - Male RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 800825 DP - 1980 Jun IS - 0362-8140 TA - Mod Vet Pract PG - 521-2 SB - M CY - UNITED STATES IP - 6 VI - 61 JC - NGO EM - 8010 PMID- 7189818 CU - 91 SO - Mod Vet Pract 1980 Jun;61(6):521-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81058417 AU - Staak C AU - Schonberg A TI - [A contribution to the technique of immunofluorescence in leptospirosis (author's transl)] LA - Ger MH - Animal MH - Antigens, Bacterial/*analysis MH - Cross Reactions MH - English Abstract MH - *Fluorescent Antibody Technique MH - Immune Sera MH - Leptospira/*immunology MH - Leptospirosis/*veterinary MH - Rabbits/immunology MH - Species Specificity MH - Swine MH - Swine Diseases/*diagnosis RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 810116 DP - 1980 Jun IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 138-41 SB - M CY - GERMANY, WEST IP - 1 VI - 247 JC - Y5P AA - Author EM - 8103 AB - Mono- and polyvalent FITC-conjugates were prepared for detection of leptospires in artifically infected material. The organisms were concentrated by centrifugation and fixed onto glass slides after they had been mixed with serum or egg albumin. By this method, leptospires were detected down to a concentration of 10(2)-10(4) organisms/ml. PMID- 7001804 CU - 91 TT - Ein Beitrag zur Durchfuhrung der Fluoreszenzserologie bei Leptospirose. EA - A SO - Zentralbl Bakteriol [A] 1980 Jun;247(1):138-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 81058415 AU - Frohlich W TI - [Demonstration of Leptospirae antibodies in the sera of immunized rabbits by the indirect immunofluorescence test (author's transl)] LA - Ger MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cross Reactions MH - English Abstract MH - *Fluorescent Antibody Technique MH - Immunization MH - Immunodiffusion MH - Leptospira/*immunology MH - Rabbits MH - Species Specificity RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810116 DP - 1980 Jun IS - 0172-5599 TA - Zentralbl Bakteriol [A] PG - 124-31 SB - M CY - GERMANY, WEST IP - 1 VI - 247 JC - Y5P AA - Author EM - 8103 AB - Antibodies of Leptospirae were demonstrated in the sera of immunized rabbits by the indirect immunofluorescence test, only after a suitable dilution of the "anti-rabbit-gamma-globulin fluorescin conjugated" was carried out in a cross reference titration ("chessboard method"). A distinct crossreaction was observed when anti-icterohaemorrhagiae - and anti-bratislava-immunsera reacted with several serotypes out of the "interrogans complex". But only a weak crossreaction was found when both sera reacted with the serotyp patoc from the "biflexa complex". The evaluation of the indirect immunofluorescence test was complicated by a streaky background of fluorescence. The agargeldiffusion tests (Ouchterolony) exhibited four, three and two precipitation bands according to the conbination of antigens and immunsera. PMID- 6776709 CU - 91 TT - Nachweis von Leptospiren-Antikorpern in Seren immunisierter Kaninchen mit Hilfe des indirekten Immunfluoreszenztestes. EA - A SO - Zentralbl Bakteriol [A] 1980 Jun;247(1):124-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 80222104 AU - Shophet R AU - Marshall RB TI - An experimentally induced predator chain transmission of Leptospira ballum from mice to cats. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cat Diseases/immunology/*transmission MH - Cats MH - Gastric Juice/metabolism MH - Leptospirosis/immunology/transmission/*veterinary MH - Mice MH - Predatory Behavior MH - Rodent Diseases/*transmission RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 800923 DP - 1980 May-Jun IS - 0007-1935 TA - Br Vet J PG - 265-70 CY - ENGLAND IP - 3 VI - 136 JC - B5C EM - 8011 PMID- 7388590 CU - 91 SO - Br Vet J 1980 May-Jun;136(3):265-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 80215834 TI - Leptospirosis [clinical conference] LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospirosis/diagnosis/epidemiology/*pathology MH - Male MH - United States PT - JOURNAL ARTICLE DA - 800828 DP - 1980 May IS - 0093-0415 TA - West J Med PG - 440-50 CY - UNITED STATES IP - 5 VI - 132 JC - XN5 EM - 8010 PMID- 7385854 CU - 88 NI - A SO - West J Med 1980 May;132(5):440-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [212 medline neighbors] UI - 80204765 AU - Adler B AU - Murphy AM AU - Locarnini SA AU - Faine S TI - Detection of specific anti-leptospiral immunoglobulins M and G in human serum by solid-phase enzyme-linked immunosorbent assay. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Cross Reactions MH - Enzyme-Linked Immunosorbent Assay MH - Human MH - IgG/*analysis MH - IgM/*analysis MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/*immunology MH - Spectrophotometry RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 800815 DP - 1980 May IS - 0095-1137 TA - J Clin Microbiol PG - 452-7 SB - M CY - UNITED STATES IP - 5 VI - 11 JC - HSH AA - Author EM - 8010 AB - The enzyme-linked immunosorbent assay (ELISA) was used to detect leptospire-specific immunoglobulin M (IgM) and IgG in the sera of patients infected with leptospiral serovars hardjo, pomona, or copenhageni. All patients produced specific IgM and IgG detectable by ELISA. In contrast, only a few patients produced IgG agglutinins whereas all produced IgM agglutinins. The specificity and sensitivity of the test suggest that the ELISA anti-IgM technique is a suitable method for detecting leptospiral antibodies in human sera for diagnostic and epidemiological purposes. PMID- 7381009 CU - 91 SO - J Clin Microbiol 1980 May;11(5):452-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 80170540 AU - Cheville NF AU - Huhn R AU - Cutlip RC TI - Ultrastructure of renal lesions in pigs with acute leptospirosis caused by Leptospira pomona. LA - Eng MH - Anemia/complications/veterinary MH - Animal MH - Female MH - Kidney/cytology/*ultrastructure MH - Kidney Diseases/pathology/*veterinary MH - Kidney Glomerulus/ultrastructure MH - Kidney Tubules/ultrastructure MH - Leptospirosis/complications/pathology/*veterinary MH - Lymph Nodes/pathology MH - Swine MH - Swine Diseases/*pathology PT - JOURNAL ARTICLE DA - 800625 DP - 1980 May IS - 0300-9858 TA - Vet Pathol PG - 338-51 SB - M CY - SWITZERLAND IP - 3 VI - 17 JC - XBQ AA - Author EM - 8008 AB - Twelve 4-day old, pathogen-free pigs were inoculated intraperitoneally with virulent L. pomona. Two pigs each were killed 1, 2, 3, 5, 7, and 14 days after inoculation and their kidneys examined by light and electron microscopy. Three to 5 days after inoculation there was hyperemia, edema and swelling of tubular epithelium; leptospires were detected intravascularly, in interstitium and embedded within basement membranes. At day 7, leptospires were at basal surfaces of proximal tubules and in phagosomes in tubular epithelium. Perivascular aggregates of monocytes and macrophages were prominent. At day 14, intersitial cells were chiefly plasmacytes and lymphocytes. Leptospires were only on tubular epithelial cell surface microvilli. In another experiment, all pigs receiving low-virulent strains had leptospires in the renal interstitium at 7 days after inoculation but had none at 14 days. All low-virulent strains produced degenerative changes and lymphocyte-plasmacytic infiltration. These studies indicate that non of the low-virulent isolates were acceptable for use in vaccines. Fialure of leptospires to remain attached to microvilli of proximal tubules in late stages of acute infection may be related to differences in virulence of various isolates. PMID- 7368526 SO - Vet Pathol 1980 May;17(3):338-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 81186530 AU - Mailloux A TI - [Human leptospiroses in the overseas departments and territories: 10 years' immunological diagnosis (1970-1979)] LA - Fre MH - English Abstract MH - French Guiana MH - Human MH - Indian Ocean Islands MH - Leptospira MH - Leptospirosis/diagnosis/*epidemiology/microbiology MH - Martinique MH - New Caledonia MH - Polynesia MH - Species Specificity MH - West Indies PT - JOURNAL ARTICLE DA - 810709 DP - 1980 May-Jun IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 229-38 SB - M CY - FRANCE IP - 3 VI - 73 JC - C4G AA - Author EM - 8109 AB - In French overseas Departments and Territories, Leptospiroses exist. In the Caribbean zone, human Leptospiroses are frequently found; in Martinique island, and some cases are recorded in French Guyana. In the Indian Ocean, "La Reunion" island, approximately 40 cases are diagnosed every year (mortality rate: 17%). In Polynesian areas, 3 serovars are found. Biological diagnosis is easier now with screening tests. Sera are to be sent to the National Leptospirosis Centre, Paris, for confirmatory test. In fact, the high incidence of Icterohaemorrhagiae serogroup does not seem to reflect the real situation, but represents the severe cases diagnosed in hospitalized patients. Minor cases remain often unnoticed. A survey of human and animal Leptospiroses would give another classification of serogroups frequency. It is important to know that 80% of Leptospiroses occur without jaundice. RO - M:CNR PMID- 7226358 LR - 820802 CU - 88 TT - Les leptospiroses humaines dans les D. O. M.-T. O. M. 10 annees de bilans immunologiques (1970-1979). EA - A SO - Bull Soc Pathol Exot Filiales 1980 May-Jun;73(3):229-38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [83 medline neighbors] UI - 80165811 AU - Pasternak JF AU - De Vivo DC AU - Prensky AL TI - Steroid-responsive encephalomyelitis in childhood. LA - Eng MH - Adrenal Cortex Hormones/*therapeutic use MH - Case Report MH - Child MH - Child, Preschool MH - Dexamethasone/therapeutic use MH - Dose-Response Relationship, Drug MH - Encephalomyelitis/diagnosis/*drug therapy MH - Female MH - Human MH - Male MH - Prednisone/therapeutic use MH - Virus Diseases/*drug therapy RN - 0 (Adrenal Cortex Hormones) RN - 50-02-2 (Dexamethasone) RN - 53-03-2 (Prednisone) PT - JOURNAL ARTICLE DA - 800627 DP - 1980 May IS - 0028-3878 TA - Neurology PG - 481-6 SB - A SB - M CY - UNITED STATES IP - 5 VI - 30 JC - NZ0 AA - Author EM - 8008 AB - The syndrome of parainfectious encephalomyelitis evolves from an antecedent infection. Several etiologic agents have been associated with this complication, although the pathogenesis in each instance may prove to be more uniform. Considerable evidence suggests that the syndrome is mediated immunologically. The seven cases reported here were clinically similar, although the infectious etiologies were diverse. Leptospirosis antedated the neurologic syndrome in two cases, and a "viral" illness preceded the other five cases. The evolution of the syndrome was slowly progressive in each case, and six patients had prominent involvement of rhombencephalic structures. The progressive course was reversed rapidly with eventual full recovery in each instance after initiation of corticosteroid therapy. Our experience with these cases coupled with a review of the literature suggests that corticosteroid therapy should be considered in the subacute or chronic cases of parainfectious encephalomyelitis. PMID- 7189253 CU - 91 SO - Neurology 1980 May;30(5):481-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 80265159 AU - Schonberg A AU - Kampe U AU - Rohloff D TI - [Methods for the detection of leptospires in sperm samples of boar] LA - Ger MH - Animal MH - Bacteriological Techniques MH - English Abstract MH - Leptospira/*isolation & purification MH - Male MH - Spermatozoa/*microbiology MH - Swine/*microbiology PT - JOURNAL ARTICLE DA - 801024 DP - 1980 May 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 166-71 CY - GERMANY, WEST IP - 9 VI - 93 JC - 9Q8 EM - 8012 PMID- 6996670 CU - 90 TT - Der Einsatz von Hemmstoffen beim kulturellen Nachweis der Leptospiren im Schweinesperma. EA - A SO - Berl Munch Tierarztl Wochenschr 1980 May 1;93(9):166-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 81053000 AU - Mackintosh CG AU - Blackmore DK AU - Marshall RB TI - Isolation of Leptospira interrogans serovars tarassovi and pomona from dogs. LA - Eng MH - Animal MH - Dog Diseases/*microbiology MH - Dogs MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Support, Non-U.S. Gov't PT - JOURNAL ARTICLE DA - 810116 DP - 1980 May IS - 0048-0169 TA - N Z Vet J PG - 100 CY - NEW ZEALAND IP - 5 VI - 28 JC - OBZ EM - 8103 PMID- 6933370 CU - 88 SO - N Z Vet J 1980 May;28(5):100 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 80222980 AU - Bakoss P AU - Kmety E TI - [Importance of absorption tests in the serotype diagnosis of leptospirosis in humans (author's transl)] LA - Slo MH - Antigens, Bacterial/*analysis MH - English Abstract MH - *Hemadsorption MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Serotyping/*methods MH - Weil's Disease/diagnosis RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 800928 DP - 1980 May IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 165-70 CY - CZECHOSLOVAKIA IP - 3 VI - 29 JC - CSH EM - 8011 PMID- 6446414 CU - 92 TT - K vyznamu vysycovacich testov v serotypovej diagnostike leptospirovych ochoreni u l'udi. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1980 May;29(3):165-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81001416 AU - Higgins R AU - Cayouette P AU - Hoquet F AU - De LaSalle F TI - Serological studies on leptospirosis in domestic animals in Quebec. LA - Eng MH - Animal MH - Animals, Domestic/*immunology MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/*veterinary MH - Quebec RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 801125 DP - 1980 Apr IS - 0008-4050 TA - Can J Comp Med PG - 229-31 SB - M CY - CANADA IP - 2 VI - 44 JC - CI0 AA - Author EM - 8101 AB - During a period of 30 months, from January 1977 to June 1979, Leptospira agglutinins were detected in 355 (6%) of 5841 bovine sera, 52 (10.1%) of 511 porcine sera, one (5%) of 20 equine sera and one (12.5%) of eight canine sera. Bovine, porcine and equine sera reacted predominantly with L. pomona. Reactors to L. hardjo/sejroe, L. icterohaemorrhagiae and L. grippotyphosa were also detected in cattle. One porcine serum reacted with L. grippotyphosa and one canine serum with L. icterohaemorrhagiae. Al the sera originated from suspected cases of leptospirosis. PMID- 7407694 CU - 91 SO - Can J Comp Med 1980 Apr;44(2):229-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 80207647 AU - Fukui H AU - Shinjo EM AU - Yanagawa R TI - Isolation of antigenic variants of leptospiras from puppies and pigs experimentally infected with Leptospira interrogans serovars canicola and pomona. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Dog Diseases/immunology/microbiology MH - Dogs/*microbiology MH - Leptospira canicola/genetics/*immunology/isolation & purification MH - Leptospira interrogans/genetics/*immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/veterinary MH - Serotyping MH - Swine/*microbiology MH - Swine Diseases/immunology/microbiology MH - Variation (Genetics) RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 800825 DP - 1980 Apr IS - 0021-5295 TA - Nippon Juigaku Zasshi PG - 177-86 CY - JAPAN IP - 2 VI - 42 JC - KRJ EM - 8010 PMID- 7382236 CU - 91 SO - Nippon Juigaku Zasshi 1980 Apr;42(2):177-86 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 80138481 AU - Cinco M AU - Coghlan JD AU - Matthews PR TI - Isolation and classification of sixteen strains of saprophytic leptospires. LA - Eng MH - England MH - Italy MH - Leptospira/*classification/isolation & purification MH - Serotyping MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 800514 DP - 1980 Apr IS - 0022-1724 TA - J Hyg (Lond) PG - 173-9 SB - M CY - ENGLAND IP - 2 VI - 84 JC - IEF AA - Author EM - 8007 AB - Sixteen strains of leptospires were isolated from surface water (14 in England and 2 in Italy) and were classified. They were all saprophytic, and nine of them belonged to known serovars: the others were found to represent new serovars within already known serogroups. PMID- 7358961 SO - J Hyg (Lond) 1980 Apr;84(2):173-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 82039077 AU - Aycardi ER AU - Torres B AU - Guzman VH AU - Cortes M TI - Leptospirosis in Colombia. Isolation of Leptospira hardjo from beef cattle grazing tropical savannas. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Colombia MH - Female MH - Gerbillinae MH - Hamsters MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Serotyping PT - JOURNAL ARTICLE DA - 811215 DP - 1980 Apr-Jun IS - 0034-9771 TA - Rev Latinoam Microbiol PG - 73-7 CY - MEXICO IP - 2 VI - 22 JC - SEP EM - 8202 PMID- 7291771 SO - Rev Latinoam Microbiol 1980 Apr-Jun;22(2):73-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 80263644 AU - Haggard DL AU - Stowe HD AU - Conner GH AU - Johnson DW TI - Immunologic effects of experimental iodine toxicosis in young cattle. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Formation/drug effects MH - Candida albicans/immunology MH - Cattle/*immunology MH - Cattle Diseases/chemically induced/immunology MH - Comparative Study MH - Female MH - Iodine/pharmacology/*toxicity MH - Leptospira/immunology MH - Leukocytes/immunology MH - Lymphocyte Transformation/drug effects MH - Phagocytosis MH - Phytohemagglutinins/immunology MH - Skin Tests RN - 0 (Antibodies, Bacterial) RN - 7553-56-2 (Iodine) PT - JOURNAL ARTICLE DA - 801027 DP - 1980 Apr IS - 0002-9645 TA - Am J Vet Res PG - 539-43 SB - M CY - UNITED STATES IP - 4 VI - 41 JC - 40C AA - Author EM - 8012 AB - A study was designed to evaluate effects of 4 dosage levels (0, 50, 250, or 1,250 mg) of daily iodine supplementation on cell-mediated and humoral immune mechanisms in 40 calves, 10 per group, for a 6-month period. Immune and inflammatory responses were measured by titers to brucella, leptospira, and infectious bovine rhinotracheitis virus vaccinations, by stimulation of lymphoctye mitoses with poke-weed, phytohemagglutinin (PHA), and conconavalin A mitogens, by intradermal PHA responses, by in vitro phagocytosis of Candida albicans by WBC, and by total WBC counts. Calves given 1,250 mg of iodine daily had significant (P = less than 0.05) decreases in persistence of antibody titers to brucella and leptospira organisms, in lymphocyte mitotic activity, in PHA injection induration, in phagocytosis by WBC, and in WBC counts. Calves fed iodine at 50 or 250 mg daily tended to have decreased leptospiral titers, lymphocyte mitoses, PHA injection induration, and in vitro phagocytosis by WBC compared with responses of controls. Seemingly, large amounts of dietary iodine interfere with titer maintenance to some antigens, with lymphocyte DNA synthesis, and with phagocytic activity of WBC. PMID- 6996540 CU - 91 SO - Am J Vet Res 1980 Apr;41(4):539-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 81039562 AU - Marshall RB AU - BAskerville A AU - Hambleton P AU - Adams GD TI - Benign leptospirosis: the pathology of experimental infection of monkeys with Leptospira interrogans serovars balcanica and tarassovi. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Brain/pathology MH - Cercopithecus MH - Female MH - Haplorhini MH - Kidney/pathology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/*pathology MH - Male MH - Meningoencephalitis/etiology/pathology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810116 DP - 1980 Apr IS - 0007-1021 TA - Br J Exp Pathol PG - 124-31 SB - M CY - ENGLAND IP - 2 VI - 61 JC - AWW AA - Author EM - 8103 AB - Grivet monkeys experimentally infected with Leptospira interrogans serovars balcanica and tarassovi showed no clinical disease, but severe meningoencephalitis was demonstrated histologically in animals killed 26 and 33 days after infection. The meningeal and perivascular reactions were exclusively lymphocytic. Mild focal lesions of degeneration and cellular infiltration were also present in the kidneys and femoral musculature. PMID- 6775660 CU - 91 SO - Br J Exp Pathol 1980 Apr;61(2):124-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 80178166 TI - Ethyl 4(5)-imidazolecarboxylate (code no. c-751) as an orally effective chemotherapeutic agent against leptospirosis. LA - Eng MH - Administration, Oral MH - Animal MH - Antibiotics/pharmacology/*therapeutic use MH - Dogs MH - Drug Resistance, Microbial MH - Female MH - Hamsters MH - Human MH - Imidazoles/pharmacology/*therapeutic use MH - Leptospira interrogans/drug effects MH - Leptospirosis/*drug therapy MH - Male MH - Mice RN - 0 (Antibiotics) RN - 0 (Imidazoles) RN - 23785-21-9 (C 751) PT - JOURNAL ARTICLE DA - 800712 DP - 1980 Apr IS - 0366-6999 TA - Chin Med J (Engl) PG - 217-26 CY - CHINA IP - 4 VI - 93 JC - D3B EM - 8009 PMID- 6768521 CU - 91 NI - A SO - Chin Med J (Engl) 1980 Apr;93(4):217-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 81014828 AU - Guedes e Silva JB AU - Paiva LM AU - Pereira da Silva JJ AU - de Souza Netto BA TI - Pathological involvement of human gastrocnemius muscle in leptospirosis (a study in 63 patients). LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Female MH - Hemagglutination Tests MH - Human MH - Hyalin MH - Leptospirosis/*pathology MH - Male MH - Middle Age MH - Muscles/*pathology MH - Necrosis PT - JOURNAL ARTICLE DA - 801120 DP - 1980 Apr IS - 0034-7310 TA - Rev Bras Pesqui Med Biol PG - 9-13 SB - M CY - BRAZIL IP - 1-3 VI - 13 JC - RK9 AA - Author EM - 8101 AB - The authors discuss the microscopic changes in gastrocnemius muscle in Leptospirosis in 63 patients. The hyaline necrosis frequently associated to a hemorrhagic infiltrate represented the most important feature in the lesional picture of the disease. Other findings were swelling, loss of cross striations, vacuolation and regenerative changes of muscle fibres. This last one was represented by multinucleated sarcoblasts and the presence of thin and strongly basophilic new-formed fibres. Interstitial hemorrhage was frequently seen and an inflammatory afflux was only rarely observed. This histological picture was considered as characteristic and highly significant for the diagnosis of Leptospirosis. PMID- 6158073 CU - 95 SO - Rev Bras Pesqui Med Biol 1980 Apr;13(1-3):9-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 80148937 AU - Little TW AU - Richards MS AU - Hussaini SN AU - Jones TD TI - The significance of leptospiral antibodies in calving and aborting cattle in south west England. LA - Eng MH - Abortion, Veterinary/*immunology MH - Age Factors MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*immunology MH - Complement Fixation Tests MH - Female MH - Fetal Death/immunology/veterinary MH - Leptospira/immunology MH - Leptospirosis/immunology/*veterinary MH - Pregnancy MH - Seasons PT - JOURNAL ARTICLE DA - 800523 DP - 1980 Mar 8 IS - 0042-4900 TA - Vet Rec PG - 221-4 SB - M CY - ENGLAND IP - 10 VI - 106 JC - XBS AA - Author EM - 8007 AB - A total of 2994 sera, from approximately equal numbers of aborting and normal calving cows, were examined for leptospiral antibodies using a complement fixation test. An analysis of the results indicated that approximately 10% of abortions were associated with leptospiral antibodies. PMID- 7361387 SO - Vet Rec 1980 Mar 8;106(10):221-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 80192812 AU - Rurangirwa FR AU - Tabel H AU - Losos GJ AU - Tizard IR TI - Immunosuppression in bovine trypanosomiasis. The establishment of "memory" in cattle infected with T. congolense and the effect of post infection serum on in vitro (3H)-thymidine uptake by lymphocytes and on leucocyte migration. LA - Eng MH - Animal MH - Antibody Formation MH - Blood MH - Cattle MH - Cell Migration Inhibition MH - *Immune Tolerance MH - Immunization MH - *Immunologic Memory MH - Leptospira/immunology MH - Leukocytes/*immunology MH - *Lymphocyte Transformation MH - Male MH - Thymidine/metabolism MH - Trypanosomiasis, Bovine/*immunology RN - 50-89-5 (Thymidine) PT - JOURNAL ARTICLE DA - 800726 DP - 1980 Mar IS - 0303-4208 TA - Tropenmed Parasitol PG - 105-10 SB - M CY - GERMANY, WEST IP - 1 VI - 31 JC - WGM AA - Author EM - 8009 AB - Cattle infected with Trypanosoma congolense were intravenously immunized with Leptospira biflexa 15 days after trypanosomal infection. The primary immune response to L. biflexa was considerably reduced as compared to uninfected controls. The infected cattle mounted a secondary response when they were cured of trypanosomes by treatment with Berenil 25 days after infection and re-immunized 8 days later. The mean secondary response in these previously infected animals was lower tha, but not significantly different from that of the uninfected control animals. Serum collected 15, 20 and 25 days after infection was inhibitory to the migration of both autologous and isologous (control) peripheral blood leucocytes. The migration inhibitory activity was abolished by heating the serum at 56 degrees C for 30 minutes implying the involvement of a heat labile serum component(s). The same serum did not modify the mitogenic effect of PHA on autologous peripheral lymphocytes. PMID- 7376244 SO - Tropenmed Parasitol 1980 Mar;31(1):105-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 81018005 AU - Baryshev PM TI - [Analysis of the antigeno-immunologic activity of heated leptospirosis vaccine in vaccinees and in an experimental study] LA - Rus MH - Adolescence MH - Adult MH - Age Factors MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacterial Vaccines/administration & dosage/*immunology MH - Child MH - English Abstract MH - Human MH - IgG/analysis MH - IgM/analysis MH - Immunologic Memory MH - Leptospira canicola MH - Leptospirosis/*prevention & control MH - Microtinae MH - Middle Age MH - Rabbits MH - Time Factors MH - *Vaccination MH - Weil's Disease/prevention & control RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 801120 DP - 1980 Mar IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 52-7 SB - M CY - USSR IP - 3 JC - Y9O AA - Author EM - 8101 AB - The comparative analysis of the immunological effectiveness of heat- killed polyvalent leptospirosis vaccine has shown the low immunological effectiveness of the whole preparation (17.8%) and its components with the exception of the antigen of the Grippotyphosa serogroup. Antibodies could be detected in the vaccinees for not more than 10 months, and they showed the properties of 19S-macroglobulin antibodies. In experiments on rabbits newly isolated Leptospira strains from human patients and wild rodents, homologous to the vaccinal strains, were found to considerably surpass the latter in their immunogenic properties; this was particularly manifest in strain "Tundra vole No. 180". The use of newly isolated Leptospira strains as vaccinal antigens is recommended. A modified heat-killed polyvalent leptospirosis vaccine should have less antigens, and the antigenic and immunogenic properties of the remaining antigens must be equivalent to those of the vaccinal antigen of Leptospira belonging to the Grippotyphosa serogroup. PMID- 6998213 CU - 91 TT - Analiz antigenno-immunologicheskoi aktivnosti gretoi leptospiroznoi vaktsiny u privitykh i v eksperimente. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1980 Mar;(3):52-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 80210764 AU - Carter ME AU - Cordes DO TI - Leptospirosis and other infections of Battus rattus and Rattus norvegicus. LA - Eng MH - Animal MH - Bacteria/isolation & purification MH - Dermatophytes/isolation & purification MH - Female MH - Leptospira/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Male MH - Parasites/isolation & purification MH - Rats MH - Rodent Diseases/*microbiology PT - JOURNAL ARTICLE DA - 800828 DP - 1980 Mar IS - 0048-0169 TA - N Z Vet J PG - 45-50 CY - NEW ZEALAND IP - 3 VI - 28 JC - OBZ EM - 8010 PMID- 6930057 CU - 88 SO - N Z Vet J 1980 Mar;28(3):45-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 80229420 AU - Palit A AU - Harrison PM TI - Serological and chemical interrelationship of antigens from Leptospira interrogans serovar canicola. LA - Eng MH - Antigens, Bacterial/analysis/*immunology MH - Carbohydrates/analysis MH - Complement Fixation Tests MH - Hemagglutination Tests MH - Immunodiffusion MH - Leptospira interrogans/analysis/*immunology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 800926 DP - 1980 Mar IS - 0022-1287 TA - J Gen Microbiol PG - 141-6 SB - M CY - ENGLAND IP - 1 VI - 117 JC - I87 AA - Author EM - 8011 AB - Antigens of the outer envelope from Leptospira interrogans serovar canicola (Hond Utrecht IV) were extracted by 50% (v/v) ethanol or by sodium dodecyl sulphate and serological analysis suggested that they were identical. The "fraction 4" extracted by alkali was found to contain glycoproteins of high (retentate) and low (filtrate) molecular weight; the latter behaved like a hapten in serology and in animal immunization experiments. Antibodies were raised in rabbits against this hapten by conjugating it to bovine albumin fraction V. The antiserum was found to react with both the low molecular weight and high molecular weight glycoproteins. This anti-hapten serum contained little or no whole-cell-agglutinating antibodies. The fraction 4 retentate behaved like a complete antigen in serological and immunization studies. Fraction 4 retentate and the outer envelope preparations were serologically related but they were not identical. Chemical studies revealed similarities between the carbohydrate component of the outer envelope obtained by ethanol extraction and fraction 4. The outer envelope extracted by ethanol, fraction 4 and its low and high molecular weight glycoproteins contained arabinose, rhamnose, fucose, xylose, mannose, galactose, glucose, glucosamine and glucuronic acid. Three unidentified peaks were observed in gas-liquid chromatographic analysis of the O-trimethylsilyl derivatives of methyl glycosides of all these samples and one of these peaks co-eluted with the O-trimethylsilyl derivative of 3-O-methylmannose. PMID- 6771366 CU - 91 SO - J Gen Microbiol 1980 Mar;117(1):141-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 80148975 AU - Thomas S TI - Leptospirosis apparently due to Leptospira bratislava in a dog. LA - Eng MH - Animal MH - Case Report MH - Dog Diseases/*microbiology MH - Dogs MH - Female MH - Leptospira/isolation & purification MH - Leptospirosis/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 800514 DP - 1980 Feb 23 IS - 0042-4900 TA - Vet Rec PG - 178-9 SB - M CY - ENGLAND IP - 8 VI - 106 JC - XBS EM - 8007 RO - M:MYA PMID- 7361415 LR - 810731 SO - Vet Rec 1980 Feb 23;106(8):178-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81080810 AU - Pearson JK AU - Mackie DP AU - Ellis WA TI - Milk drop syndrome resulting from Leptospira hardjo [letter] LA - Eng MH - Animal MH - Case Report MH - Cattle/physiology MH - Cattle Diseases/*etiology MH - Female MH - *Lactation MH - Leptospirosis/etiology/*veterinary MH - Pregnancy PT - LETTER DA - 810219 DP - 1980 Feb 9 IS - 0042-4900 TA - Vet Rec PG - 135-6 SB - M CY - ENGLAND IP - 6 VI - 106 JC - XBS EM - 8104 PMID- 7445334 CU - 91 SO - Vet Rec 1980 Feb 9;106(6):135-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 81062184 AU - Milner AR AU - Wilks CR AU - Morgan IR AU - Rosen NE TI - Leptospira serogroup Hebdomadis infection as an Australian zoonosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Australia MH - Cattle MH - Cattle Diseases/diagnosis/*etiology MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/diagnosis/etiology/*veterinary MH - Male MH - Support, Non-U.S. Gov't MH - *Zoonoses/diagnosis RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810126 DP - 1980 Feb IS - 0005-0423 TA - Aust Vet J PG - 70-3 SB - M CY - AUSTRALIA IP - 2 VI - 56 JC - 9IE AA - Author EM - 8103 AB - Two cases of leptospirosis due to infection with a member of the Hebdomadis serogroup are described in farm workers on a Victorian dairy farm. The source of infection appeared to be the milking herd which had elevated serum antibody titres against a member of the Hebdomadis serogroup. Agglutinin-absorption testing of one patient's serum indicated that the infecting serovar was hardjo. A survey of 1,144 cattle entering abattoirs throughout the State indicated that 44.3% of these animals showed serological evidence of past or present infection with leptospira of the Hebdomadis serogroup and the potential risk for people with occupational contact with cattle is emphasised. The importance of considering leptospirosis in the differential diagnosis of all patients with influenza-like symptoms or pyrexia of unknown origin and having occupational contact with animals, especially cattle, is discussed. PMID- 7436893 CU - 91 SO - Aust Vet J 1980 Feb;56(2):70-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 81001454 AU - Corin RE AU - Cox CD TI - Characterization of leptospiral catalase and peroxidase. LA - Eng MH - Catalase/antagonists & inhibitors/*isolation & purification MH - Comparative Study MH - Electrophoresis, Polyacrylamide Gel MH - Hydrogen-Ion Concentration MH - Leptospira/*enzymology MH - Leptospira interrogans/enzymology MH - Peroxidases/antagonists & inhibitors/*isolation & purification MH - Support, U.S. Gov't, P.H.S. RN - EC 1.11.1. (Peroxidases) RN - EC 1.11.1.6 (Catalase) PT - JOURNAL ARTICLE ID - A1-10982 DA - 801124 DP - 1980 Feb IS - 0008-4166 TA - Can J Microbiol PG - 121-9 SB - M CY - CANADA IP - 2 VI - 26 JC - CJ3 AA - Author EM - 8101 AB - Peroxidase from Leptospira biflexa strain B-16 ad catalase from Leptospira interrogans canicola Hond Utrecht were characterized and compared and both appeared to be heme enzymes as judged by their inhibition profiles and rapid inactivation during catalysis. Neither enzyme exhibited monovalent or divalent cation requirements. Dialysis of cell-free extracts resulted in loss of peroxidase activity but catalase was unaffected by this procedure. Peroxidase had a Km for H2O2 of 12.5 microM while catalase had a Km of 70 mM for H2O2. Catalase and peroxidase were physically separated by sedimentation in linear sucrose gradients. The specific activities of each enzyme seemed to be a function of the state of growth at which the cells were harvested and both enzymes were found associated with membranes, peroxidase by hydrophobic and catalase by ionic interactions. Speculative deductions are presented concerning the phylogenetic interrelationships of both enzymes as well as their significance in the biology and pathogenicity of leptospires. PMID- 7407701 SO - Can J Microbiol 1980 Feb;26(2):121-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 80253653 AU - Petricevic I AU - Tomljenovic V TI - [Miliary pulmonary manifestations in leptospirosis--report of a case (author's transl)] LA - Scr MH - Adolescence MH - Case Report MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis MH - Lung Diseases/*diagnosis/etiology MH - Male PT - JOURNAL ARTICLE DA - 801027 DP - 1980 Feb IS - 0024-3477 TA - Lijec Vjesn PG - 135-6 CY - YUGOSLAVIA IP - 3 VI - 102 JC - L6C EM - 8012 PMID- 7401889 TT - Milijarne plucne promjene u toku leptospiroze--prikaz bolesnika. EA - A SO - Lijec Vjesn 1980 Feb;102(3):135-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81187978 TI - [Investigation of natural infective foci of leptospirosis (author's transl)] LA - Chi MH - Animal MH - China MH - *Disease Reservoirs MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/*transmission MH - Rats/microbiology MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 810709 DP - 1980 Feb TA - Chung Hua Yu Fang I Hsueh Tsa Chih PG - 10-3 CY - CHINA IP - 1 VI - 14 JC - D74 EM - 8109 RO - M:MYA PMID- 7227076 LR - 820923 CU - 88 NI - A SO - Chung Hua Yu Fang I Hsueh Tsa Chih 1980 Feb;14(1):10-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 80095396 AU - Adler B AU - Faine S TI - Immunogenicity of boiled compared with formalized leptospiral vaccines in rabbits, hamsters and humans. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - *Antibody Formation MH - Bacterial Vaccines/administration & dosage/*immunology MH - Comparative Study MH - Cross Reactions MH - Formaldehyde/*pharmacology MH - Guinea Pigs MH - Hamsters MH - *Heat MH - Hemagglutination Tests MH - Human MH - Injections, Intradermal MH - Leptospira interrogans/drug effects/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 800327 DP - 1980 Feb IS - 0022-1724 TA - J Hyg (Lond) PG - 1-10 SB - M CY - ENGLAND IP - 1 VI - 84 JC - IEF AA - Author EM - 8005 AB - Leptospires (Leptospira interrogans serovar pomona) grown in chemically defined medium were immunogenic when given intradermally in humans if the leptospires were killed with formalin but not if they were boiled. Boiled leptospires were immunogenic for rabbits and hamsters and protected hamsters from challenge infection. On the other hand, boiled leptospires of the biflexa complex, serovar patoc, did retain some immunogenicity in humans, but the antisera did not protect hamsters against challenge with serovar pomona. PMID- 7188698 CU - 85 SO - J Hyg (Lond) 1980 Feb;84(1):1-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 80198085 AU - Hambleton P AU - Baskerville A AU - Marshall RB AU - Harris-Smith PW AU - Adams GD TI - Metabolic sequelae of experimental leptospirosis in grivet monkeys. LA - Eng MH - Alanine Aminotransferase/blood MH - Animal MH - Aspartate Aminotransferase/blood MH - Blood Proteins/metabolism MH - Cercopithecus MH - Creatine Kinase/blood MH - Haplorhini MH - Hydroxybutyrate Dehydrogenase/blood MH - Iron/blood MH - Lactate Dehydrogenase/blood MH - Leptospira interrogans MH - Weil's Disease/*blood/enzymology MH - Zinc/blood RN - EC 1.1.1.27 (Lactate Dehydrogenase) RN - EC 1.1.1.30 (Hydroxybutyrate Dehydrogenase) RN - EC 2.6.1.1 (Aspartate Aminotransferase) RN - EC 2.6.1.2 (Alanine Aminotransferase) RN - EC 2.7.3.2 (Creatine Kinase) RN - 0 (Blood Proteins) RN - 7439-89-6 (Iron) RN - 7440-66-6 (Zinc) PT - JOURNAL ARTICLE DA - 800828 DP - 1980 Feb IS - 0007-1021 TA - Br J Exp Pathol PG - 16-21 SB - M CY - ENGLAND IP - 1 VI - 61 JC - AWW AA - Author EM - 8010 AB - Leptospira interrogans serovars balcanica and tarassovi both induced mild subclinical infections in grivet monkeys. The activities in serum of lactate dehydrogenase, alpha-hydroxybutyrate dehydrogenase, aspartate aminotransferase, alanine aminotransferase and creatine phosphokinase and the level of alpha 1-antichymotrypsin increased in a few days after infection. Concomitant decreases in serum iron levels were observed in some cases. These changes occurred in the absence of any observable clinical signs though there were histopathological lesions in some organs. No haematological changes or alterations in other sreum components were detected. PMID- 6769455 CU - 91 SO - Br J Exp Pathol 1980 Feb;61(1):16-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 80115184 AU - Davidson JN AU - Hirsh DC TI - Leptospirosis in lambs. LA - Eng MH - Animal MH - Case Report MH - Female MH - Leptospirosis/microbiology/*veterinary MH - Sheep MH - Sheep Diseases/*microbiology PT - JOURNAL ARTICLE DA - 800425 DP - 1980 Jan 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 124-5 SB - M CY - UNITED STATES IP - 2 VI - 176 JC - HAV AA - Author EM - 8006 AB - Two major episodes of acute hemolytic disease in lambs were associated with high mortality. Clinical signs were severe depression, dyspnea, and tachycardia. Gross postmortem findings included hemoglobinuria and icterus. Histologic examination revealed tubular necrosis and periacinar hepatocellular necrosis. Leptospira interrogans serotype pomona was proposed as the causative agent because high serum antibody titers for this bacterium were found in lambs and ewes in the affected flocks. PMID- 7353986 SO - J Am Vet Med Assoc 1980 Jan 15;176(2):124-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 80100118 AU - Thompson A TI - The first New Zealand isolation of Leptospira interrogans serovar australis [letter] LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/*microbiology MH - Male MH - New Zealand MH - *Serotyping PT - LETTER DA - 800327 DP - 1980 Jan 9 IS - 0028-8446 TA - N Z Med J PG - 28 SB - M CY - NEW ZEALAND IP - 651 VI - 91 JC - OBQ EM - 8005 PMID- 6928064 CU - 91 SO - N Z Med J 1980 Jan 9;91(651):28 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 81129423 AU - Hartman EG AU - Broekhuizen S TI - Antibodies to Leptospira in European hares (Lepus europaeus Pallas) in the Netherlands. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Female MH - Leptospira interrogans/classification/*immunology MH - Male MH - Netherlands MH - Rabbits/*immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810421 DP - 1980 IS - 0514-7166 TA - Zentralbl Veterinarmed [B] PG - 640-9 CY - GERMANY, WEST IP - 8 VI - 27 JC - Y72 EM - 8106 PMID- 7468005 CU - 91 SO - Zentralbl Veterinarmed [B] 1980;27(8):640-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81108913 AU - Regolisti M AU - Bautz C TI - [Observations on cases of leptospirosis in the Val d'Arda (Piacenza) district] LA - Ita MH - Adolescence MH - Adult MH - Child MH - English Abstract MH - Female MH - Human MH - Italy MH - Leptospirosis/*epidemiology/physiopathology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 810317 DP - 1980 Jan-Mar IS - 0004-0312 TA - Arch Sci Med (Torino) PG - 145-7 SB - M CY - ITALY IP - 1 VI - 137 JC - 8FU AA - Author EM - 8105 AB - 23 cases of leptospirosis hospitalized in the Medical Division of the Fiorenzuola d'Arda Hospital, over a period of 12,5 years, have been examined from the clinical and statistical point of view. PMID- 7458648 CU - 88 TT - Considerazioni su una casistica di leptospirosi osservata nel comprensorio della Val d'Arda (Piacenza)] EA - A SO - Arch Sci Med (Torino) 1980 Jan-Mar;137(1):145-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 81081736 AU - Aycardi ER AU - Myers DM AU - Torres B TI - A new leptospiral serovar in the Tarassovi serogroup from Colombia. LA - Eng MH - Agglutination Tests MH - Animal MH - Colombia MH - Cross Reactions MH - Kidney/microbiology MH - Leptospira/*classification/immunology/isolation & purification MH - Opossums/microbiology PT - JOURNAL ARTICLE DA - 810226 DP - 1980 IS - 0514-7166 TA - Zentralbl Veterinarmed [B] PG - 425-8 CY - GERMANY, WEST IP - 5 VI - 27 JC - Y72 EM - 8104 PMID- 7445835 CU - 84 SO - Zentralbl Veterinarmed [B] 1980;27(5):425-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 81066116 AU - Liu SM TI - [Moyamoya disease caused by leptospiral arteritis (author's transl)] LA - Chi MH - Adolescence MH - Adult MH - Arterial Occlusive Diseases/*etiology MH - Arteritis/*complications MH - Cerebral Angiography MH - Child MH - Child, Preschool MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Moyamoya Disease/*etiology/radiography PT - JOURNAL ARTICLE DA - 810219 DP - 1980 IS - 0412-4057 TA - Chung Hua Shen Ching Ching Shen Ko Tsa Chih PG - 140-2 CY - CHINA IP - 3 VI - 13 JC - D7Y EM - 8104 PMID- 7438901 CU - 90 SO - Chung Hua Shen Ching Ching Shen Ko Tsa Chih 1980;13(3):140-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 80192381 AU - Baryshev PM AU - Shkrob OS AU - Tsoi DM AU - Dreizina AM AU - Tur'ianov MKh TI - [Case of leptospirosis difficult for diagnosis in epidemiologic and clinical practice] LA - Rus MH - Case Report MH - English Abstract MH - Female MH - Human MH - Leptospira interrogans MH - Leptospirosis/*diagnosis/pathology MH - Middle Age MH - Weil's Disease/diagnosis/pathology PT - JOURNAL ARTICLE DA - 800712 DP - 1980 IS - 0040-3660 TA - Ter Arkh PG - 119-21 CY - USSR IP - 2 VI - 52 JC - VLU EM - 8009 PMID- 7376088 TT - O sluchae leptospiroza, trudnom dlia raspoznavaniia v epidemiologicheskoi i klinicheskoi praktike. EA - A SO - Ter Arkh 1980;52(2):119-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 83066181 AU - Myers DM TI - Leptospiral antibodies in stray dogs of Moreno, Province of Buenos Aires, Argentina. LA - Eng MH - Agglutination Tests MH - Agglutinins/analysis MH - Animal MH - Antibodies, Bacterial/*analysis MH - Argentina MH - Dog Diseases/*microbiology MH - Dogs MH - Leptospira/*immunology MH - Leptospirosis/*veterinary RN - 0 (Agglutinins) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 830127 DP - 1980 Jan-Apr IS - 0325-7541 TA - Rev Argent Microbiol PG - 18-22 SB - M CY - ARGENTINA IP - 1 VI - 12 JC - QZ8 AA - Author EM - 8303 AB - A serologic survey for leptospirosis in stray dogs from Moreno, Province of Buenos Aires, was carried out. Sera from 143 randomly collected animals were examined by the microscopic agglutination test. A total of 73 (51.0%) of the dogs have had contact with leptospirae. The predominant leptospiral agglutinnins were to serovar canicola (37.0%) and to a lesser degree against the serovar antigens pyrogenes (4.8%) and autumnalis (2.0%). Although a high percentage of seropositive reactions occurred against the serovar antigens ballum, pyrogenes and icterohaemorrhagiae, all the reactions against ballum and icterohaemorrhagiae, and the majority of the reactions to pyrogenes represented the natural coagglutinins frequently associated with serovar canicola. The detection of antibodies to the Autumnalis group in dogs of Argentina could be new and suggest the emergence of canine infections caused by a serovar of this serogroup which should be sought out and identified. PMID- 7348314 CU - 91 SO - Rev Argent Microbiol 1980 Jan-Apr;12(1):18-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81254447 AU - Trap D AU - Gaumont R TI - [Serological diagnosis of leptospirosis. Comparison of results obtained by macroscopic agglutination in slide test and agglutination-lysis test (author's transl)] LA - Fre MH - Agglutination Tests/*veterinary MH - Animal MH - *Animals, Domestic MH - Antibodies, Bacterial/analysis MH - Comparative Study MH - English Abstract MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis/immunology RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 810922 DP - 1980 IS - 0003-4193 TA - Ann Rech Vet PG - 241-44 SB - M CY - FRANCE IP - 3 VI - 11 JC - 5ZT EM - 8111 PMID- 7259028 CU - 91 TT - Diagnostic serologique de la leptospirose. Comparaison des resultats obtenus par une epreuve d'agglutination sur lame avec ceux de l'agglutination-lyse. EA - A SO - Ann Rech Vet 1980;11(3):241-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 82082634 AU - Ellinghausen HC Jr TI - A review of selected references dealing with Leptospira interrogans serovar (serotype) Hardjo. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - *Leptospira interrogans/classification/isolation & purification MH - Leptospirosis/diagnosis/veterinary MH - Serotyping/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 820212 DP - 1980 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 240-64 CY - UNITED STATES VI - 84 JC - PY5 EM - 8204 RF - 60 PMID- 7031674 CU - 90 SO - Proc Annu Meet U S Anim Health Assoc 1980;84:240-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [98 medline neighbors] UI - 81007051 AU - Frerichs GN AU - Chandler MD TI - Estimation of residual free formaldehyde in biological products. LA - Eng MH - Bacterial Vaccines/*analysis MH - Clostridium/immunology MH - Comparative Study MH - Escherichia coli/immunology MH - Formaldehyde/*analysis MH - Leptospira/immunology MH - Methods MH - Quality Control MH - Vaccines, Attenuated/*analysis RN - 0 (Bacterial Vaccines) RN - 0 (Vaccines, Attenuated) RN - 50-00-0 (Formaldehyde) PT - JOURNAL ARTICLE DA - 801124 DP - 1980 IS - 0092-1157 TA - J Biol Stand PG - 139-44 SB - M CY - ENGLAND IP - 2 VI - 8 JC - HJD EM - 8101 PMID- 6997315 CU - 92 SO - J Biol Stand 1980;8(2):139-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 81080760 AU - Murdoch D TI - Leptospiral uveitis. LA - Eng MH - Adult MH - Agglutination Tests MH - Animal MH - Case Report MH - Cattle MH - Cattle Diseases/microbiology MH - Female MH - Human MH - Leptospirosis/*complications/diagnosis MH - Male MH - Middle Age MH - Uveitis/diagnosis/*microbiology PT - JOURNAL ARTICLE DA - 810224 DP - 1980 IS - 0300-8983 TA - Trans Ophthalmol Soc N Z PG - 73-5 CY - NEW ZEALAND VI - 32 JC - W9O EM - 8104 PMID- 6934653 CU - 88 SO - Trans Ophthalmol Soc N Z 1980;32:73-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 81056175 AU - Lehmans J AU - Henocq E AU - Bazin JC AU - Laurent J AU - Lagrue G TI - [Anaerobic oro-pharyngeal flora and immunopathology (author's transl)] LA - Fre MH - Bacillus/immunology MH - Bacterial Infections/immunology/therapy MH - English Abstract MH - Human MH - Hypersensitivity, Delayed MH - Hypersensitivity, Immediate MH - Injections, Intradermal MH - Kidney Diseases/microbiology MH - Leptospira/immunology MH - Micrococcus/immunology MH - Oropharynx/*microbiology MH - Pharyngitis/etiology MH - Spirochaeta/immunology MH - Treponema/immunology PT - JOURNAL ARTICLE DA - 810116 DP - 1980 IS - 0035-1768 TA - Rev Stomatol Chir Maxillofac PG - 253-8 SB - M SB - D CY - FRANCE IP - 4 VI - 81 JC - T8M EM - 8103 PMID- 6933683 CU - 88 TT - Flore anaerobie oro-pharyngee et immunopathologie. EA - A SO - Rev Stomatol Chir Maxillofac 1980;81(4):253-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 80154515 AU - Przytulski T AU - Porzeczkowska D TI - Studies on genetic resistance to leptospirosis in pigs. LA - Eng MH - Animal MH - Female MH - *Genetic Markers MH - *Immunity, Natural MH - Leptospirosis/genetics/prevention & control/*veterinary MH - Male MH - Swine MH - Swine Diseases/genetics/*prevention & control RN - 0 (Genetic Markers) PT - JOURNAL ARTICLE DA - 800616 DP - 1980 Jan-Feb IS - 0007-1935 TA - Br Vet J PG - 25-32 CY - ENGLAND IP - 1 VI - 136 JC - B5C EM - 8008 PMID- 6928794 CU - 92 SO - Br Vet J 1980 Jan-Feb;136(1):25-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 83093979 AU - Zettl K TI - [Veterinary tasks and preventive measures in sheep breeding. Infectious and invasive diseases of various degrees of importance] LA - Ger MH - Actinomycosis/veterinary MH - Animal MH - Bacterial Infections/*veterinary MH - Clostridium Infections/veterinary MH - Corynebacterium Infections/veterinary MH - Leptospirosis/veterinary MH - Parasitic Diseases/*veterinary MH - Paratuberculosis MH - Sarcocystosis/veterinary MH - Sheep MH - *Sheep Diseases/diagnosis/prevention & control MH - Toxoplasmosis, Animal PT - JOURNAL ARTICLE DA - 830214 DP - 1980 IS - 0303-6286 TA - Tierarztl Prax PG - 147-61 SB - M CY - GERMANY, WEST IP - 2 VI - 8 JC - VS4 EM - 8304 PMID- 6817461 CU - 91 TT - Tierarztliche Aufgaben und Massnahmen in der Schafhaltung. 3. Infektions- und Invasionskrankheiten von unterschiedlicher Bedeutung (a). SO - Tierarztl Prax 1980;8(2):147-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 81029196 AU - Stoianova NA AU - Popova EM TI - [Use of mercamine for differentiating IgM and IgG antibodies in Leptospira infection] LA - Rus MH - Agglutination Tests/methods MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/diagnosis MH - Cysteamine/*diagnostic use MH - English Abstract MH - Human MH - IgG/*analysis MH - IgM/*analysis MH - Leptospirosis/*diagnosis MH - Rabbits RN - 0 (Antibodies, Bacterial) RN - 60-23-1 (Cysteamine) PT - JOURNAL ARTICLE DA - 801218 DP - 1980 IS - 0023-6748 TA - Lab Delo PG - 626-8 CY - USSR IP - 10 JC - KYU EM - 8102 PMID- 6158616 CU - 95 TT - Primenenie merkamina dlia differentsiatsii IgM- i IgG-antitel pri leptospiroznoi infektsii. EA - A SO - Lab Delo 1980;(10):626-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 81010718 AU - Labanovskaia ZhL AU - Silonova GI AU - Selitser IS TI - [Changes in blood serum lipid metabolic indices in acute hepatitis] LA - Rus MH - Acute Disease MH - Comparative Study MH - English Abstract MH - Enterovirus Infections/blood MH - Hepatitis/*blood MH - Hepatitis, Alcoholic/blood MH - Hepatitis, Toxic/blood MH - Hepatitis, Viral, Human/blood MH - Human MH - Jaundice/blood MH - Leptospirosis/blood MH - Lipids/*blood PT - JOURNAL ARTICLE DA - 801120 DP - 1980 IS - 0023-6748 TA - Lab Delo PG - 522-6 CY - USSR IP - 9 JC - KYU EM - 8101 PMID- 6157917 CU - 95 TT - Izmeneniia pokazatelei lipidnogo obmena syvorotki krovi pri ostrykh gepatitakh. EA - A SO - Lab Delo 1980;(9):522-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 81010683 AU - Sarukhanova LE AU - Volina EG AU - Kiktenko VS AU - Ezhov GI TI - [Leptospira cultivation on serum-free liquid nutrient media] LA - Rus MH - Animal MH - Comparative Study MH - Culture Media/*metabolism MH - English Abstract MH - Leptospira/*growth & development/metabolism MH - Serum Albumin/metabolism MH - Sheep/blood RN - 0 (Culture Media) RN - 0 (Serum Albumin) PT - JOURNAL ARTICLE DA - 801120 DP - 1980 IS - 0023-6748 TA - Lab Delo PG - 439-41 CY - USSR IP - 7 JC - KYU EM - 8101 PMID- 6157882 CU - 95 TT - Kul'tivirovanie leptosir na zhidkikh bessyvorotochnykh pitatel'nykh sredakh. EA - A SO - Lab Delo 1980;(7):439-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 80192234 AU - Dion WM AU - Dukes TW TI - Bovine mycotic abortion caused by Acremonium kiliense Grutz. LA - Eng MH - Abomasum/microbiology MH - Abortion, Veterinary/*etiology MH - Acremonium/isolation & purification/pathogenicity MH - Animal MH - Case Report MH - Cattle MH - Cattle Diseases/*etiology MH - Female MH - Hyphomycetes/isolation & purification/pathogenicity MH - Mice MH - Mycoses/etiology/*veterinary MH - Placenta/microbiology MH - Pregnancy MH - Pregnancy Complications, Infectious/etiology/*veterinary PT - JOURNAL ARTICLE DA - 800712 DP - 1979 Dec IS - 0036-2174 TA - Sabouraudia PG - 355-61 SB - M CY - SCOTLAND IP - 4 VI - 17 JC - U5U AA - Author EM - 8009 AB - Acremonium kiliense was cultured from the placenta and abomasal contents of an aborted bovine foetus; attempts to isolate viruses and bacteria were unsuccessful although the serum of the dam contained antibodies to Leptospira pomona. The fungus was nonpathogenic for mice but was able to survive in murine tissues for at least 13 weeks. The possibility of this case being a foetal infection as a result of insemination with contaminated semen is discussed. PMID- 575677 CU - 85 SO - Sabouraudia 1979 Dec;17(4):355-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 80177097 AU - Wiles WA TI - Leptospirosis (Weil's disease) in Zimbabwe Rhodesia--a proven case. LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospirosis/blood/*epidemiology/pathology MH - Male MH - Zimbabwe PT - JOURNAL ARTICLE DA - 800712 DP - 1979 Dec IS - 0008-9176 TA - Cent Afr J Med PG - 261-2 CY - ZIMBABWE IP - 12 VI - 25 JC - CQO EM - 8009 PMID- 544030 CU - 88 SO - Cent Afr J Med 1979 Dec;25(12):261-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 80161283 AU - Martone WJ AU - Kaufmann AF TI - Leptospirosis in humans in the United States, 1974-1978 [news] LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - United States PT - NEWS DA - 800625 DP - 1979 Dec IS - 0022-1899 TA - J Infect Dis PG - 1020-2 SB - A SB - M CY - UNITED STATES IP - 6 VI - 140 JC - IH3 EM - 8008 PMID- 541520 CU - 91 SO - J Infect Dis 1979 Dec;140(6):1020-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 80158846 AU - Singh SP TI - Electron-microscopic studies of the effect of distilled water as washing fluid on Leptospira. LA - Eng MH - Leptospira/*ultrastructure MH - Microscopy, Electron MH - *Water RN - 7732-18-5 (Water) PT - JOURNAL ARTICLE DA - 800625 DP - 1979 Dec IS - 0019-6479 TA - Indian Vet J PG - 991-2 CY - INDIA IP - 12 VI - 56 JC - GM9 EM - 8008 PMID- 541115 LI - P SO - Indian Vet J 1979 Dec;56(12):991-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 80153128 AU - Adler B AU - Bragger JM TI - Lethal infections caused by Leptospira interrogans serovar hardjo in immunosuppressed hamsters [letter] LA - Eng MH - Animal MH - Antibody Formation/drug effects MH - Cyclophosphamide/*adverse effects MH - Hamsters MH - Immunosuppression/adverse effects/*veterinary MH - Leptospira interrogans/immunology MH - Leptospirosis/etiology/immunology/*veterinary MH - Mice MH - Rodent Diseases/*etiology/immunology RN - 50-18-0 (Cyclophosphamide) PT - LETTER DA - 800523 DP - 1979 Dec IS - 0005-0423 TA - Aust Vet J PG - 600-1 SB - M CY - AUSTRALIA IP - 12 VI - 55 JC - 9IE EM - 8007 PMID- 539944 CU - 91 SO - Aust Vet J 1979 Dec;55(12):600-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 80137954 AU - Rahman M AU - Macis FR TI - Pseudo-leptospires in blood culture. LA - Eng MH - Blood/*microbiology MH - Culture Media MH - Diagnostic Errors MH - Female MH - Human MH - Jaundice/microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis MH - Male PT - JOURNAL ARTICLE DA - 800523 DP - 1979 Dec IS - 0021-9746 TA - J Clin Pathol PG - 1226-7 SB - A SB - M CY - ENGLAND IP - 12 VI - 32 JC - HT3 AA - Author EM - 8007 AB - Spiral filaments seen in the blood cultures of two patients with fever and jaundice were initially thought to be leptospires; these were later proved to be artefacts. An investigation was carried out to exclude the possibility of laboratory contamination of the culture media and to find out how these objects were produced. The significance of the findings is discussed in relation to the possibility of a mistaken diagnosis in routine laboratories which have a limited experience of leptospires. PMID- 536458 SO - J Clin Pathol 1979 Dec;32(12):1226-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 80136536 AU - Caldas EM AU - Sampaio MB TI - Leptospirosis in the city of Salvador, Bahia, Brazil: a case-control seroepidemiologic study. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Agglutinins/analysis MH - Animal MH - Antibodies, Bacterial/analysis MH - Brazil MH - Carrier State MH - Dog Diseases/transmission MH - Dogs MH - Female MH - Human MH - Leptospirosis/*etiology/immunology/transmission/veterinary MH - Male MH - Occupational Diseases/etiology/veterinary MH - Rats MH - Seasons MH - Sex Factors PT - JOURNAL ARTICLE DA - 800530 DP - 1979 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 85-96 SB - M CY - TAIWAN IP - 2 VI - 6 JC - GTK AA - Author EM - 8007 AB - From January 1 to December 31 of 1975, all patients admitted to Salvador's Infectious Disease Hospital were serologically tested for leptospirosis if their clinical and laboratory findings were compatible with this diagnosis. Of the 888 patients tested, 133 were positive. Among patients with an initial clinical impression of leptospirosis, the diagnosis was confirmed serologically in 36% and for the 133 leptospirosis patients, only 67 (50.4%) were initially suspected. Epidemiological aspects investigated covered: age, sex, place of residence and occupation for all cases and for fatal cases; distribution of cases by month of occurrence and by rainfall in that month; distribution of serotypes by month; and probable source of infection with emphasis of the occurrence and type of contact with dogs. For each case residing in Salvador, a control of the same age and sex was interviewed in the immediate neighborhood. Sewage, rats, water, dogs, mud and garbage were identified as the most likely source of infection in that order. Marked seasonal fluctuations were apparent with peak incidence during the months of maximum precipitation. In two- thirds of cases reporting contact with a dog, tests on the animal revealed the same serotype. The most frequent serotypes were: icterohemorrhagiae, autumnalis, castellonis, grippotyphosa, hebdomadis and bataviae. RO - M:MYA PMID- 536125 LR - 810731 SO - Int J Zoonoses 1979 Dec;6(2):85-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 80114539 AU - Rurangirwa FR AU - Tabel H AU - Losos GJ AU - Tizard IR TI - Suppression of antibody response to Leptospira biflexa and Brucella abortus and recovery from immunosuppression after Berenil treatment. LA - Eng MH - Amidines/*therapeutic use MH - Animal MH - Antibodies, Bacterial/analysis MH - *Antibody Formation MH - Brucella abortus/*immunology MH - Cattle MH - Diminazene/*therapeutic use MH - Immunization MH - Leptospira/*immunology MH - Male MH - Trypanocidal Agents/*therapeutic use MH - Trypanosomiasis, Bovine/*immunology RN - 536-71-0 (Diminazene) PT - JOURNAL ARTICLE DA - 800423 DP - 1979 Dec IS - 0019-9567 TA - Infect Immun PG - 822-6 SB - M CY - UNITED STATES IP - 3 VI - 26 JC - GO7 AA - Author EM - 8006 AB - Zebu cattle infected with either Trypanosoma congolense EATRO 1800 or Trypanosoma vivax EATRO 1721 had suppressed humoral immune responses to Leptospira biflexa injected intravenously and to attenuated Brucella abortus injected subcutaneously. T. congolense infections were more suppressive than T. vivax infections. In cattle infected with T. vivax, the suppression of immune responses to both bacterial immunogens was abrogated when the animals were treated with Berenil at the time of antigen administration. In cattle infected with T. congolense, simultaneous Berenil treatment at the time of vaccination abolished the suppression of immune response to L. biflexa, and lessened but did not abrogate the suppression of immune response to B. abortus. PMID- 118933 CU - 91 SO - Infect Immun 1979 Dec;26(3):822-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 80097803 AU - Shimono E AU - Sugiyama K AU - Yanagawa R TI - Specificity of serovar-specific main antigens of leptospiras shown by the inhibition of leptospiral microscopic agglutination. LA - Eng MH - Agglutination MH - Agglutination Tests MH - Antigens, Bacterial/*immunology MH - *Epitopes MH - Leptospira interrogans/*immunology PT - JOURNAL ARTICLE DA - 800324 DP - 1979 Dec IS - 0021-5295 TA - Nippon Juigaku Zasshi PG - 623-8 CY - JAPAN IP - 6 VI - 41 JC - KRJ EM - 8005 PMID- 93155 CU - 95 SO - Nippon Juigaku Zasshi 1979 Dec;41(6):623-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 80238452 AU - Metcalfe RV AU - Bettelheim KA AU - Berry ME AU - Hobbs KM AU - Thompson AL AU - Cole SP TI - Studies on antibody levels to Brucella abortus, Toxoplasma gondii and Leptospira serogroups in sera collected by the National Serum Bank during 1974-1976. LA - Eng MH - Adult MH - Agglutination Tests MH - Antibodies/*analysis MH - Antibodies, Bacterial/*analysis MH - Blood Banks MH - Brucella abortus/*immunology MH - Complement Fixation Tests MH - Female MH - Fluorescent Antibody Technique MH - Human MH - Leptospira/*immunology MH - Male MH - Middle Age MH - New Zealand MH - Toxoplasma/*immunology MH - Urban Population RN - 0 (Antibodies) RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 800928 DP - 1979 Dec IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 520-6 SB - M CY - GERMANY, WEST IP - 4 VI - 245 JC - Y52 AA - Author EM - 8011 AB - The New Zealand National Serum Bank is a collection of human sera consisting predominantly of specimens taken from healthy New Zealand blood donors. The studies presented here were designed to assess the antibody levels in two urban centres to Brucella abortus, Toxoplasma gondii and several Leptospiral serogroups including all those found in New Zealand. In none of the sera could complement fixing leptospiral antibodies be detected. There was evidence of low level immunity to both Toxoplasma gondii and Brucella abortus. PMID- 44946 CU - 94 SO - Zentralbl Bakteriol [Orig A] 1979 Dec;245(4):520-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 80100096 AU - Blackmore DK AU - Bell L AU - Schollum L TI - Leptospirosis in meat inspectors: preliminary results of a serological survey. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - *Food Inspection MH - Human MH - Leptospira/*immunology MH - Leptospirosis/epidemiology MH - *Meat MH - New Zealand MH - Occupational Diseases/epidemiology MH - *Occupations MH - Swine PT - JOURNAL ARTICLE DA - 800324 DP - 1979 Nov 28 IS - 0028-8446 TA - N Z Med J PG - 415-8 SB - M CY - NEW ZEALAND IP - 648 VI - 90 JC - OBQ AA - Author EM - 8005 AB - A serological survey of leptospirosis among more than 1000 meat inspectors, from meat works throughout New Zealand, revealed a serological prevalence at a minimum serum dilution of 1:24, of 10.2 percent. Eighty-five percent of serological reactions were to serovars pomona and tarassovi. A highly significant correlation was demonstrated between the serological prevalence of these serovars and the inspection of pigs. Evidence is provided to substantiate the use of titres as low as 1:24 as an indication of previous leptospiral infection. Forty-two inspectors reported medical evidence of previous clinical infection with leptospirosis. Analysis of those who still exhibited a serological response and their individual case histories, indicated that detectable titres of leptospirosis can exist for up to 10 years. PMID- 293569 CU - 88 SO - N Z Med J 1979 Nov 28;90(648):415-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 80119204 AU - Garcia Garcia M AU - Darnell Tey A AU - Bergada Barado E AU - Revert Torrellas L TI - [Icterohemorrhagic leptospirosis with acute renal failure (author's transl)] LA - Spa MH - Adult MH - Agglutination Tests MH - Case Report MH - English Abstract MH - Human MH - Kidney Failure, Acute/*etiology/immunology MH - Male MH - Middle Age MH - Weil's Disease/*complications/immunology PT - JOURNAL ARTICLE DA - 800425 DP - 1979 Nov 25 IS - 0025-7753 TA - Med Clin (Barc) PG - 362-6 SB - M CY - SPAIN IP - 9 VI - 73 JC - LTQ AA - Author EM - 8006 AB - Icterohemorrhagic leptospirosis is a zoonosis which is relatively frequent in rural agricultural or cattle areas. In the severe forms of the disease renal affection is frequent, but the incidence of acute renal insufficiency is far lesser. Three cases of acute renal insufficiency in adult male patients secondary to an infection by Leptospira icterohaemorrhagiae are presented. Two of the patients resided in urban areas and only one of which presented professional risk. The clinical polymorphysm of the illness is confirmed, having observed not only the absence of fever but also that of jaundice. The former history of chronic alcoholism, present in two cases, determined diagnostic difficulties with acute alcoholic hepatitis. The serologic diagnosis is often positive only at the end of the second week, and the need to carry out a series of seroaglutinations is to be insisted upon. The types of renal impairment in leptospirosis are reviewed and the presence of acute renal insufficiency is stressed, including those patients with less severe forms of the disease, and especially those without Weil's syndrome. All of the patients had to be treated with dialysis, although two of them had a conserved diuresis after an initial brief period of oliguria. PMID- 529871 TT - Leptospirosis icterohemorragica con insuficiencia renal aguda. EA - A SO - Med Clin (Barc) 1979 Nov 25;73(9):362-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 80168437 AU - Orr HS AU - Little TW TI - Isolation of Leptospira of the serotype hardjo from bovine kidneys. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle/immunology/*microbiology MH - Culture Media MH - Guinea Pigs MH - Hamsters MH - Kidney/*microbiology MH - Leptospira/growth & development/immunology/*isolation & purification MH - Mice RN - 0 (Antibodies, Bacterial) RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 800627 DP - 1979 Nov IS - 0034-5288 TA - Res Vet Sci PG - 343-6 SB - M CY - ENGLAND IP - 3 VI - 27 JC - R7D AA - Author EM - 8008 AB - Thirteen strains of Leptospira serotype hardjo were cultured from 200 bovine kidneys collected from an abattoir. All strains grew on primary isolation in EMJH medium 0.1 per cent Noble agar but most failed to grow in a variety of media containing neomycin or 5-fluorouracil as selective agents. Two of the cattle from which hardjo were isolated were seronegative by the microscopic agglutination test against hardjo, two had titres of 1/100, five of 1/400, three of 1/1600 and one of 1/6400. PMID- 542724 CU - 91 SO - Res Vet Sci 1979 Nov;27(3):343-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 80094173 AU - Riemann HP AU - Ruppanner R AU - Willeberg P AU - Franti CE AU - Elliott WH AU - Fisher RA AU - Brunetti OA AU - Aho JH Jr AU - Howarth JA AU - Behymer DE TI - Serologic profile of exotic deer at Point Reyes National Seashore. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/analysis MH - Bacterial Infections/immunology/veterinary MH - California MH - Cattle/immunology MH - Cattle Diseases/immunology MH - Deer/*immunology MH - Virus Diseases/immunology/veterinary PT - JOURNAL ARTICLE DA - 800327 DP - 1979 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 911-3 SB - M CY - UNITED STATES IP - 9 VI - 175 JC - HAV AA - Author EM - 8005 AB - Serotests were conducted on axis (Axis axis) and fallow (Dama dama) deer at Point Reyes National Seashore to determine their status with respect to nine diseases enzootic to the native black-tailed deer (Odocoileus hemionus columbianus) or to resident dairy cattle. In the exotic deer, the proportion of animals that were seropositive included: anaplasmosis, 35%; bluetongue, 48%; brucellosis, 0%; bovine viral diarrhea, 2%; infectious bovine rhinotracheitis, 3%; leptospirosis, 7%; parainfluenza-3, 49%; toxoplasmosis, 8%; and Q fever, 51%. The prevalence of antibodies among a small sample of the black-tailed deer included anaplasmosis, 100%; toxoplasmosis, 29%; and Q fever, 57%. The antibody prevalences in a sample of dairy cattle in the area included anaplasmosis, 19%; toxoplasmosis, 8%; and Q fever, 100%. PMID- 521370 SO - J Am Vet Med Assoc 1979 Nov 1;175(9):911-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 80094171 AU - Marler RJ AU - Cook JE AU - Kerr AI AU - Kruckenberg SM TI - Serologic survey for leptospirosis in coyotes in northcentral Kansas. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Carnivora/*immunology MH - Kansas MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 800327 DP - 1979 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 906-8 SB - M CY - UNITED STATES IP - 9 VI - 175 JC - HAV AA - Author EM - 8005 AB - During 1975 to 1977, serum samples were collected from 101 adult coyotes (Canis latrans) captured in northcentral Kansas. Ten samples were seropositive by microagglutination testing and six of those samples were seropositive for multiple serovars. Titers for Leptospira interrogans serovars grippotyphosa, pyrogenes, djasiman, butembo, and pomona were demonstrated. PMID- 521368 SO - J Am Vet Med Assoc 1979 Nov 1;175(9):906-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 80121408 AU - Edwards JD AU - Daines D TI - A leptospirosis outbreak in a piggery. LA - Eng MH - Abortion, Veterinary/etiology MH - Animal MH - Antibodies/therapeutic use MH - Antibodies, Bacterial/analysis MH - Case Report MH - Disease Outbreaks/veterinary MH - Female MH - Leptospirosis/complications/drug therapy/immunology/*veterinary MH - Male MH - Pregnancy MH - Swine MH - Swine Diseases/*drug therapy/immunology PT - JOURNAL ARTICLE DA - 800423 DP - 1979 Nov IS - 0048-0169 TA - N Z Vet J PG - 247-8 CY - NEW ZEALAND IP - 11 VI - 27 JC - OBZ EM - 8006 RO - M:MYA PMID- 294532 LR - 810814 CU - 88 SO - N Z Vet J 1979 Nov;27(11):247-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 80121407 AU - Shophet R TI - A serological survey of leptospirosis in cats. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cat Diseases/*epidemiology/immunology MH - Cats MH - Female MH - Leptospira/immunology/pathogenicity MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Male MH - New Zealand MH - Serology PT - JOURNAL ARTICLE DA - 800423 DP - 1979 Nov IS - 0048-0169 TA - N Z Vet J PG - 236, 245-6 CY - NEW ZEALAND IP - 11 VI - 27 JC - OBZ EM - 8006 PMID- 294531 CU - 88 SO - N Z Vet J 1979 Nov;27(11):236, 245-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 81057437 AU - Weaver AD TI - Extramural study experience and practical experience of final year veterinary students of nine European schools. LA - Eng MH - Curriculum MH - *Education, Veterinary MH - Europe MH - Students PT - JOURNAL ARTICLE DA - 810126 DP - 1979 Oct 13 IS - 0042-4900 TA - Vet Rec PG - 351-03 SB - M CY - ENGLAND IP - 15 VI - 105 JC - XBS AA - Author EM - 8103 AB - Arrangements for extramural education including "seeing practice" experience in nine European veterinary schools (Bristol, Glasgow, Liverpool, Helsinki, Stockholm, Hannover, Ghent, Toulouse and Vienna) are described. Considerable differences existed between three UK schools, and between them and the Continental schools, where arrangements were usually voluntary. The amount of extramural experience in different types of work was quantified by student questionnaires. An average of 12 weeks' experience in farm practice was gained by 83 per cent of the 339 students, six weeks' small animal work by 48 per cent, four weeks in an abattoir by 43 per cent and other periods in specialised practices, laboratories and veterinary faculties. Practice abroad was experienced by 10 per cent. The total experience of different medical and surgical conditions varied considerably between schools as a result of disease eradication (eg, swine fever in UK), non-occurrence (canine leptospirosis in Sweden and Finland) or the availability of surgical or reproductive material, as well as on other factors. PMID- 552728 SO - Vet Rec 1979 Oct 13;105(15):351-03 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 80111098 AU - Kosina F AU - Haasova L AU - Truksova D TI - [Problems of leptospirosis (author's transl)] LA - Cze MH - Adult MH - Case Report MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 800426 DP - 1979 Oct 12 IS - 0008-7335 TA - Cas Lek Cesk PG - 1226-9 CY - CZECHOSLOVAKIA IP - 40-41 VI - 118 JC - CPY EM - 8006 PMID- 526998 TT - Problemy leptospiroz. EA - A SO - Cas Lek Cesk 1979 Oct 12;118(40-41):1226-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 80066351 AU - Coghlan JD TI - Leptospirosis in man, British Isles, 1978. LA - Eng MH - Adult MH - Animal MH - Cattle MH - Cattle Diseases/microbiology MH - Disease Outbreaks/epidemiology MH - Great Britain MH - Human MH - Leptospira/classification/isolation & purification MH - Leptospirosis/*epidemiology/microbiology/veterinary MH - Male PT - JOURNAL ARTICLE DA - 800215 DP - 1979 Oct 6 IS - 0007-1447 TA - Br Med J PG - 872 SB - A SB - M CY - ENGLAND IP - 6194 VI - 2 JC - B4W EM - 8004 PMID- 509148 CU - 88 SO - Br Med J 1979 Oct 6;2(6194):872 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 80219901 AU - Durfee PT AU - Presidente PJ TI - Experimental infection of calves and sheep with Leptospira interrogans serovar balcanica. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals, Suckling MH - Antibodies, Bacterial/biosynthesis MH - Antibody Specificity MH - Cattle MH - *Cattle Diseases MH - Colostrum/immunology MH - Female MH - Leptospira interrogans/immunology/isolation & purification MH - Pregnancy MH - Sheep MH - *Sheep Diseases MH - Urine/microbiology MH - Weil's Disease/immunology/*veterinary RN - 0 (Antibodies, Bacterial) PT - JOURNAL ARTICLE DA - 800815 DP - 1979 Oct IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 447-53 SB - M CY - AUSTRALIA IP - 5 VI - 57 JC - 9FW AA - Author EM - 8010 AB - Two of four calves inoculated with Leptospira interrogans serovar balcanica developed low microscopic agglutinating (MA) titres to serovar hardjo. A third calf had an MA titre of 1:1024 by day 19 post- inoculation (PI). Transient leptospiruria was recorded in one calf on days 12 and 13 PI. An in-contact calf did not seroconvert. None of the calves had fever or other clinical signs of disease. Four ewes inoculated with balcanica developed MA titres to hardjo by day 13 PI, and a transient leptospiruria between days 14 and 25 PI. None of the ewes showed any evidence of clinical disease and three of them delivered healthy lambs 22 to 64 days PI. One ewe had mild lesions of focal interstitial nephritis. PMID- 548016 CU - 91 SO - Aust J Exp Biol Med Sci 1979 Oct;57(5):447-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 80116082 AU - Stamm LV AU - Charon NW TI - Plate assay for detection of Leptospira interrogans serovar pomona hemolysin. LA - Eng MH - Hemolysins/*analysis MH - Leptospira interrogans/*metabolism MH - Methods MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE DA - 800423 DP - 1979 Oct IS - 0095-1137 TA - J Clin Microbiol PG - 590-2 SB - M CY - UNITED STATES IP - 4 VI - 10 JC - HSH EM - 8006 PMID- 528687 CU - 90 SO - J Clin Microbiol 1979 Oct;10(4):590-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 80107502 AU - Inzana TJ AU - Dawe DL TI - Experimentally induced Leptospira interrogans serovar autumnalis infections in young swine. LA - Eng MH - Administration, Intranasal MH - Animal MH - Comparative Study MH - Conjunctiva MH - Injections MH - Kidney/microbiology MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/etiology/microbiology/*veterinary MH - Swine MH - Swine Diseases/*etiology/microbiology PT - JOURNAL ARTICLE DA - 800327 DP - 1979 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1355-8 SB - M CY - UNITED STATES IP - 10 VI - 40 JC - 40C AA - Author EM - 8005 AB - Leptospira interrogans serovar autumnalis strain 621 was proven to be infective for swine by intranasal and ocular inoculation and by contact exposure. The course of the disease was that of a chronic asymptomatic infection. Throughout the experiment, leptospires were observed in all tissues examined by darkfield microscopy of 10% tissue suspensions and examination by indirect fluorescent antibody technique of frozen tissue sections. Infected pigs had increasing antibody titers, as determined by the microscopic agglutination test. The organism spread from intranasally inoculated pigs to contact controls. PMID- 525853 SO - Am J Vet Res 1979 Oct;40(10):1355-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 80144012 AU - Mackintosh CG AU - Thompson JC TI - A rapid method for the detection of leptospiraemia [letter] LA - Eng MH - Animal MH - Centrifugation/methods MH - Leptospira/*cytology/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Microbiological Techniques MH - Microscopy/*methods PT - LETTER DA - 800514 DP - 1979 Oct IS - 0048-0169 TA - N Z Vet J PG - 224-5 CY - NEW ZEALAND IP - 10 VI - 27 JC - OBZ EM - 8007 PMID- 395467 CU - 91 SO - N Z Vet J 1979 Oct;27(10):224-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 80078635 AU - Ris DR AU - Hamel KL TI - The isolation of leptospires from an air-conditioning plant [letter] LA - Eng MH - *Air Conditioning MH - Human MH - Leptospira/*isolation & purification MH - New Zealand MH - *Water Microbiology PT - LETTER DA - 800215 DP - 1979 Sep 12 IS - 0028-8446 TA - N Z Med J PG - 212 SB - M CY - NEW ZEALAND IP - 643 VI - 90 JC - OBQ EM - 8004 PMID- 292862 CU - 91 SO - N Z Med J 1979 Sep 12;90(643):212 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 80104153 AU - Dikken H AU - Kmety E AU - de Geus A AU - Timmer VE TI - A new leptospiral serovar in The pyrogenes serogroup. LA - Eng MH - Adolescence MH - Agglutination Tests MH - Cross Reactions MH - Human MH - Kenya MH - Leptospira/*immunology MH - Leptospirosis/microbiology MH - Male MH - Serotyping PT - JOURNAL ARTICLE DA - 800324 DP - 1979 Sep IS - 0041-3232 TA - Trop Geogr Med PG - 405-8 SB - M CY - NETHERLANDS IP - 3 VI - 31 JC - WGJ AA - Author EM - 8005 AB - A new leptospiral serovar in the Pyrogenes serogroup is described. Parallel investigations by the 'classical' cross-agglutinin absorption test method and the 'factor analysis' method determined the serological properties of the new serovar. The serovar name kwale with reference strain Julu is proposed. PMID- 524450 SO - Trop Geogr Med 1979 Sep;31(3):405-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 80052288 AU - Kanazawa Y TI - [A case of Leptospira hebdomadis infection treated with piperacillin (author's transl)] LA - Jpn MH - Adult MH - Case Report MH - English Abstract MH - Human MH - Leptospirosis/diagnosis/*drug therapy MH - Male MH - Penicillins/*therapeutic use MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 800119 DP - 1979 Sep IS - 0021-4906 TA - Jpn J Antibiot PG - 966-70 SB - M CY - JAPAN IP - 9 VI - 32 JC - KHV AA - Author EM - 8003 AB - A 35-year-old male went fishing at the Agano River side in the suburbs of Toyosaka City, in August 1977. He was admitted to the hospital then with the chief complaints of high fever and severe headache on the 5th day of illness. Following the intravenous drip infusion of 12 g piperacillin for 6 1/2 days, he became afebrile within 2 days and recovered rapidly. Bacteriological examination disclosed none of significant data. Serum agglutinin reaction for leptospirosis, however, was positive in a titer up to 1:2,560 to L. hebdomadis, except for L. icterohemorrhagiae, L. autumnalis, L. australis and L. canicola. PMID- 501924 EA - A SO - Jpn J Antibiot 1979 Sep;32(9):966-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 79252979 AU - Smith TF AU - Wold AD AU - Fairbanks VF AU - Washington JA 2d AU - Wilkowske CJ TI - Pseudospirochetes, a cause of erroneous diagnoses of leptospirosis. LA - Eng MH - Adult MH - Case Report MH - Culture Media MH - Erythrocytes MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 791026 DP - 1979 Sep IS - 0002-9173 TA - Am J Clin Pathol PG - 459-63 SB - A SB - M CY - UNITED STATES IP - 3 VI - 72 JC - 3FK AA - Author EM - 7912 AB - Motile filaments of varying lengths and thicknesses were observed by darkfield microscopy in a blood culture of a specimen from a patient who had fever of unknown origin. Similar structures were also seen in cultures inoculated with donor blood from healthy controls. Since the movement and configuration of the structures were not characteristic for spirochetes, the morphologic features were further examined by electron microscopy. The filaments observed were identical in appearance to pseudospirochetes described more than 50 years ago. The authors' observations indicate that they are derived from erythrocytes. Because of possible confusion of these pseudospirochetes with living organisms, the diagnosis of leptospirosis by darkfield microscopy should be confirmed by cultural or serologic tests. PMID- 474526 SO - Am J Clin Pathol 1979 Sep;72(3):459-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 80078725 AU - Hathaway SC AU - Marshall RB TI - Experimental infection of sheep with Leptospira interrogans: serovars hardjo and balcanica [letter] LA - Eng MH - Animal MH - Leptospira interrogans/isolation & purification MH - Sheep MH - Sheep Diseases/*microbiology MH - Weil's Disease/microbiology/*veterinary PT - LETTER DA - 800226 DP - 1979 Sep IS - 0048-0169 TA - N Z Vet J PG - 197 CY - NEW ZEALAND IP - 9 VI - 27 JC - OBZ EM - 8004 PMID- 292934 CU - 91 SO - N Z Vet J 1979 Sep;27(9):197 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 80078724 AU - Marshall RB AU - Broughton ES AU - Hathaway SC TI - Protection of sheep by vaccination against artificial challenge with Leptospira interrogans serovar hardjo. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Female MH - Leptospira interrogans/immunology MH - Sheep MH - Sheep Diseases/*prevention & control MH - Vaccination MH - Weil's Disease/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 800226 DP - 1979 Sep IS - 0048-0169 TA - N Z Vet J PG - 195 CY - NEW ZEALAND IP - 9 VI - 27 JC - OBZ EM - 8004 PMID- 292933 CU - 88 SO - N Z Vet J 1979 Sep;27(9):195 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 82070510 AU - Wang SQ AU - Zhang RZ AU - Li ZH AU - Liu YM AU - Tan MW AU - Zhang JS AU - Yang BJ TI - [Study on avirulent Leptospira pomona live vaccine in swine (author's transl)] LA - Chi MH - Animal MH - Bacterial Vaccines/*standards MH - English Abstract MH - Hamsters MH - Leptospira/*immunology/pathogenicity MH - Swine MH - Vaccination MH - Virulence RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 820222 DP - 1979 Sep TA - Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao PG - 87-92 CY - CHINA IP - 1 VI - 1 JC - CZS EM - 8204 PMID- 262819 CU - 91 EA - A SO - Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao 1979 Sep;1(1):87-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 80171588 AU - Antoniadis A AU - Papapanagiotou J TI - Serological evidence of human leptospirosis in northern Greece. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Complement Fixation Tests MH - Diagnosis, Differential MH - Epitopes MH - Human MH - Leptospira/*immunology MH - Occupations MH - Weil's Disease/*diagnosis RN - 0 (Antibodies, Bacterial) RN - 0 (Epitopes) PT - JOURNAL ARTICLE DA - 800625 DP - 1979 Sep IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 546-51 SB - M CY - GERMANY, WEST IP - 4 VI - 244 JC - Y52 AA - Author EM - 8008 AB - a) 1069 human blood samples were tested for the presence of C. F. antibodies to leptospirae. 98 of these sera were from patients suffering from Weil's syndrome. 13 out of 98 patients were found to be suffering from leptospirosis; one of these died. 460 sera were from patients with febrile (acute) illness of unknown origin and 511 sera from patients with respiratory disease (especially "influenza like disease"). None of these patients was found to be suffering from leptospirosis. b) 191 human sera from healthy people at risk to leptospiral infection were examined by microscopic agglutination test (MAT). A high percentage (14.1%) was found to have antibodies against one or two leptospiral serogroups. The results obtained suggest that the incidence of leptospiral infections in humans in Northern Greece is higher than previously reported and the predominant serogroups were found to be Icterohaemorrhagiae followed by Autumnalis and Canicola. PMID- 94493 CU - 95 SO - Zentralbl Bakteriol [Orig A] 1979 Sep;244(4):546-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 80083041 AU - Brittin EE TI - A different treatment recommended for leptospirosis in the dog [letter] LA - Eng MH - Animal MH - Chlorpheniramine/therapeutic use MH - Dexamethasone/therapeutic use MH - Dihydrostreptomycin Sulfate/therapeutic use MH - Dog Diseases/*drug therapy MH - Dogs MH - Drug Combinations MH - Leptospirosis/drug therapy/*veterinary MH - Penicillin G, Procaine/therapeutic use PT - LETTER DA - 800226 DP - 1979 Sep IS - 0042-4889 TA - Vet Med Small Anim Clin PG - 1204 CY - UNITED STATES IP - 9 VI - 74 JC - XBO EM - 8004 PMID- 92847 CU - 95 SO - Vet Med Small Anim Clin 1979 Sep;74(9):1204 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 80027577 AU - Kawaoka Y AU - Naiki M AU - Yanagawa R TI - Radioimmunoassay system using a serovar-specific lipopolysaccharide antigen of Leptospira. LA - Eng MH - Antibodies, Bacterial MH - Antigens, Bacterial/*analysis MH - Epitopes MH - Immune Sera MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Lipopolysaccharides/*immunology MH - Radioimmunoassay PT - JOURNAL ARTICLE DA - 791227 DP - 1979 Sep IS - 0095-1137 TA - J Clin Microbiol PG - 313-6 SB - M CY - UNITED STATES IP - 3 VI - 10 JC - HSH AA - Author EM - 8002 AB - The serovar-specific main (TM) antigen of Leptospira interrogans serovar kremastos strain Kyoto was labeled with sodium boro[3H]hydride after 1 h of oxidation with periodate. When 50 ng of the labeled compound was employed, 50% of the compound was bound to the antibodies contained in 7.5 x 10(-2) nl of anti-kremastos Kyoto serum. Under this condition, only 9 ng of the homologous TM antigen was required for 50% inhibition of serovar kremastos Kyoto 3H-TM antigen-anti-kremastos Kyoto serum binding, whereas 5,000 times as much TM antigen of serovar hebdomadis, which belongs to the same Hebdomadis serogroup as serovar kremastos, was required for the same inhibition. The TM antigens from serovars pomona, icterohaemorrhagiae, and copenhageni, which belong to different serogroups, showed no inhibition in an amount of up to 3 x 10(3), 2 x 10(5), and 2 x 10(5) ng, respectively. In the inhibition study using the serovar hebdomadis TM antigen, inhibition values slightly fluctuated due to the antigen's insolubility. When the TM antigens were solubilized with 0.1% sodium taurodeoxycholate, the fluctuation in inhibition values was minimized, and the cross- reactivity of the serovar hebdomadis TM antigen with anti-kremastos Kyoto serum was diminished, while the inhibitory activity of the serovar kremastos Kyoto TM antigen was enhanced. PMID- 90682 CU - 95 SO - J Clin Microbiol 1979 Sep;10(3):313-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 80012370 AU - Szalka A AU - Binder L TI - [Leptospira icterohaemorrhagiae infections] LA - Hun MH - Adult MH - Animal MH - Bites and Stings MH - Case Report MH - Disease Vectors MH - Female MH - Human MH - Hungary MH - Laboratory Infection/*transmission MH - Leptospira interrogans/isolation & purification MH - Male MH - Rats/*microbiology MH - Rodent Control MH - Weil's Disease/prevention & control/*transmission MH - Zoonoses PT - JOURNAL ARTICLE DA - 791121 DP - 1979 Aug 5 IS - 0030-6002 TA - Orv Hetil PG - 1869-72 CY - HUNGARY IP - 31 VI - 120 JC - OL8 EM - 8001 RO - M:MYA PMID- 481886 LR - 810729 TT - Leptospira icterohaemorrhagiae fertozesek. SO - Orv Hetil 1979 Aug 5;120(31):1869-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 80107623 AU - Nervig RM AU - Garrett LA TI - Use of furosemide to obtain bovine urine samples for leptospiral isolation. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*urine MH - Diuretics MH - Female MH - *Furosemide/pharmacology MH - Leptospira/*isolation & purification MH - Leptospirosis/urine/*veterinary PT - JOURNAL ARTICLE DA - 800327 DP - 1979 Aug IS - 0002-9645 TA - Am J Vet Res PG - 1197-1200 SB - M CY - UNITED STATES IP - 8 VI - 40 JC - 40C AA - Author EM - 8005 AB - The use of the diuretic furosemide made it possible to obtain samples of urine from cattle for leptospiral isolations. The drug was injected IV at a dose level of 0.8 mg/kg for heifers and 0.5 mg/kg for calves. The average time to first voiding in heifers was 19 minutes. The average time from the first to the second voiding was 17 minutes. The average time to the first voiding in four calves was 12 minutes; the average time from the first to the second voiding was 10 minutes. A decrease in urinary osmolarity provoked by furosemide created a more favorable condition for the survival of leptospires. Leptospires were isolated in 24 (72.7%) of 33 weekly cultural attempts with the aid of furosemide in three experimentally infected adult cattle. Serovar hardjo was isolated in 16 (57.1%) of 28 weekly cultural attempts with aid of the diuretic in four experimentally infected calves. The recovery frequency was 28.5% from the first voiding and 50% from the second. Leptospires were not isolated from urine obtained from the calves by manual stimulation. Untoward side effects that might have been attributable to furosemide were not observed. Furosemide appears to be well suited to obtain urine samples from cattle for leptospiral isolation. PMID- 525924 SO - Am J Vet Res 1979 Aug;40(8):1197-1200 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 80107606 AU - Marler RJ AU - Cook JE AU - Kerr AI TI - Experimentally induced leptospirosis in coyotes (Canis latrans). LA - Eng MH - Animal MH - *Carnivora MH - Female MH - Leptospira/pathogenicity MH - Leptospirosis/immunology/transmission/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 800327 DP - 1979 Aug IS - 0002-9645 TA - Am J Vet Res PG - 1115-19 SB - M CY - UNITED STATES IP - 8 VI - 40 JC - 40C AA - Author EM - 8005 AB - Infection of coyotes (Canis latrans) with Leptospira interrogans serovars pomona, canicola, and copenhageni was accomplished by percutaneous inoculation. Bacteriologic, serologic, histopathologic, and fluorescent antibody techniques were used to investigate the infections. Leptospiremia was established with pomona. Leptospiruria was demonstrated with the three serovars. Serovar canicola was recovered from one coyote 134 days after it was inoculated. PMID- 525917 SO - Am J Vet Res 1979 Aug;40(8):1115-19 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 80096344 AU - De Brito T AU - Bohm GM AU - Yasuda PH TI - Vascular damage in acute experimental leptospirosis of the guinea-pig. LA - Eng MH - Acute Disease MH - Animal MH - Capillaries/*ultrastructure MH - Diaphragm/blood supply MH - Endothelium/ultrastructure MH - Female MH - Guinea Pigs MH - Hemorrhagic Diathesis/etiology/pathology MH - Kidney/blood supply MH - Lung/blood supply MH - Microscopy, Electron MH - Weil's Disease/complications/*pathology PT - JOURNAL ARTICLE DA - 800317 DP - 1979 Aug IS - 0022-3417 TA - J Pathol PG - 177-82 SB - M CY - ENGLAND IP - 4 VI - 128 JC - JLB AA - Author EM - 8005 AB - The pathogenesis of the haemorrhagic diathesis in experimental leptospirosis of the guinea-pig was investigated in the lung, diaphragm and kidney. The vascular damage was found to be focal and mainly capillary. Swollen endothelium with dilated endoplasmic reticulum, enlarged mitochondriae and open junctions seemed to be the initial lesions and endothelial necrosis the final picture in all tissues. The lung capillaries showed endothelial and epithelial blebs and desquamation with many myelin figures. Capillary thrombosis was observed in the pulmonary microcirculation, probably acting as an aggravating factor and being partly responsible for the particularly impressive lung haemorrhages. The peritubular renal capillaries as well as open junctions and gaps due to necrosis also had enlarged fenestrae which were permeable to colloidal carbon particles. The paucity of micro-organisms in the vicinity of the lesions is in accordance with the toxic genesis postulated for the vascular damage in leptospirosis. It is suggested that the vascular lesions induced by leptospirosis begin with increased permeability prior to endothelial necrosis. PMID- 521862 SO - J Pathol 1979 Aug;128(4):177-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [211 medline neighbors] UI - 80015934 AU - Kariuk SE AU - Zadorozhnaia EA AU - Fedorov EI AU - Trubetskaia IA TI - [Clinical and epidemiological characteristics of leptospirosis] LA - Rus MH - English Abstract MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Ukraine PT - JOURNAL ARTICLE DA - 791128 DP - 1979 Aug IS - 0049-6804 TA - Vrach Delo PG - 116-9 CY - USSR IP - 8 JC - XLS EM - 8001 PMID- 483741 CU - 88 TT - Kliniko-epidemiologicheskaia kharakteristika bol'nykh leptospirozom. EA - A SO - Vrach Delo 1979 Aug;(8):116-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 80055165 AU - Ris DR AU - Hamel KL TI - Leptospira interrogans serovar pomona vaccines with different adjuvants in cattle. LA - Eng MH - *Adjuvants, Immunologic MH - Aluminum Hydroxide/administration & dosage MH - Animal MH - Cattle/*immunology MH - Cattle Diseases/immunology/prevention & control MH - Clinical Trials MH - Comparative Study MH - Freund's Adjuvant/administration & dosage MH - Leptospira interrogans/*immunology MH - Suspensions MH - Vaccination/veterinary MH - Weil's Disease/immunology/prevention & control/*veterinary PT - CLINICAL TRIAL PT - JOURNAL ARTICLE DA - 800119 DP - 1979 Aug IS - 0048-0169 TA - N Z Vet J PG - 169-71 CY - NEW ZEALAND IP - 8 VI - 27 JC - OBZ EM - 8003 PMID- 388262 CU - 90 SO - N Z Vet J 1979 Aug;27(8):169-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 80038343 AU - Litvin VIu AU - Alekseeva IP TI - [Susceptibility and sensitivity of the Siberian lemming and Middendorff's vole to leptospirae of the grippotyphosa serogroup] LA - Rus MH - Animal MH - Antibodies, Bacterial/analysis MH - English Abstract MH - Female MH - Leptospira/*pathogenicity MH - Leptospirosis/immunology/microbiology MH - Male MH - Microtinae/*microbiology MH - Rodentia/*microbiology MH - Siberia MH - Time Factors MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 791220 DP - 1979 Aug IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 90-4 SB - M CY - USSR IP - 8 JC - Y9O AA - Author EM - 8002 AB - Siberian lemmings and Middendorf's voles were found to be susceptible to infection caused by Leptospira of the Grippotyphosa serogroup after the intraperitoneal injection of Leptospira culture, the application of the culture or infected urine to the skin, as well as after Leptospira- carrying animals were placed together with the animals to be infected. The infectious sensitivity of these animals to Leptospira was not high: leptospiruria was observed for 1-3 weeks; in some of the voles leptospiruria was slightly pronounced, whereas other voles had a great number of Leptospira in urine. Antibodies appeared in the blood on day 5 after infection, and their titers increased till days 61-63. In no case could Leptospira be isolated from the kidneys of the animals killed on days 61-83 of the experiment. PMID- 386660 CU - 90 TT - O vospriimchivosti i chuvstvitel'nosti sibirskogo lemminga i polevki Middendorfa k leptospiram serogruppy grippotyphosa. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1979 Aug;(8):90-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 84012634 AU - Saunders JP TI - Clinical features and management of leptospirosis in Malaysia. LA - Eng MH - Doxycycline/therapeutic use MH - Human MH - Leptospirosis/*diagnosis/drug therapy RN - 564-25-0 (Doxycycline) PT - JOURNAL ARTICLE DA - 831123 DP - 1979 Aug IS - 0126-8635 TA - Malays J Pathol PG - 7-9 CY - MALAYSIA VI - 2 JC - LFW EM - 8401 PMID- 263425 SO - Malays J Pathol 1979 Aug;2:7-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 84012625 AU - Joseph PG TI - Leptospirosis in animals in West Malaysia. LA - Eng MH - Animal MH - Animals, Domestic MH - Animals, Laboratory MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 831123 DP - 1979 Aug IS - 0126-8635 TA - Malays J Pathol PG - 15-21 CY - MALAYSIA VI - 2 JC - LFW EM - 8401 PMID- 263418 CU - 88 SO - Malays J Pathol 1979 Aug;2:15-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 84012624 AU - Supramaniam V TI - Leptospirosis in the Malaysian army. LA - Eng MH - Human MH - Leptospirosis/*epidemiology/prevention & control MH - Malaysia MH - *Military Medicine PT - JOURNAL ARTICLE DA - 831123 DP - 1979 Aug IS - 0126-8635 TA - Malays J Pathol PG - 11-4 CY - MALAYSIA VI - 2 JC - LFW EM - 8401 PMID- 263417 CU - 88 SO - Malays J Pathol 1979 Aug;2:11-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 84012623 AU - Tan DS TI - Leptospirosis in West Malaysia--epidemiology and laboratory diagnosis. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Child, Preschool MH - Ethnic Groups MH - Female MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Malaysia MH - Male MH - Middle Age MH - Occupations PT - JOURNAL ARTICLE DA - 831123 DP - 1979 Aug IS - 0126-8635 TA - Malays J Pathol PG - 1-6 CY - MALAYSIA VI - 2 JC - LFW EM - 8401 PMID- 263416 CU - 88 SO - Malays J Pathol 1979 Aug;2:1-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 80020600 AU - Myers DM TI - [Evaluation of the outer envelope antigens of leptospira in complement fixation and hemagglutination tests for leptospirosis] LA - Spa MH - Animal MH - Antigens, Bacterial/*analysis MH - Complement Fixation Tests MH - English Abstract MH - Hemagglutination Tests MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*immunology MH - Rabbits MH - Rats PT - JOURNAL ARTICLE DA - 791227 DP - 1979 Aug IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 141-51 CY - UNITED STATES IP - 2 VI - 87 JC - AGG EM - 8002 PMID- 158370 CU - 92 TT - Evaluacion de antigenos de la envoltura externa de Leptospira en las pruebas de fijacion de complemento y de hemaglutinacion para la leptospirosis. EA - A SO - Bol Oficina Sanit Panam 1979 Aug;87(2):141-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 80083438 AU - Rzhevskii ER AU - Kaplinskii MB AU - Sverdlov AK AU - Dvornik VF AU - Filimonov VB TI - [Natural foci infections in the Urals] LA - Rus MH - Adult MH - Animal MH - Communicable Diseases/*epidemiology MH - *Disease Reservoirs MH - Disease Vectors MH - Encephalitis, Tick-Borne/epidemiology MH - Erysipeloid/epidemiology MH - Hemorrhagic Fever with Renal Syndrome/epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Q Fever/epidemiology MH - Rodentia MH - USSR PT - JOURNAL ARTICLE PT - REVIEW DA - 800215 DP - 1979 Aug IS - 0300-9114 TA - Voen Med Zh PG - 42-4 CY - USSR IP - 8 JC - XGS EM - 8004 RF - 17 PMID- 42216 CU - 94 TT - Prirodno-ochagovye infektsii na Urale. SO - Voen Med Zh 1979 Aug;(8):42-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 80141018 AU - Shirakawa M AU - Yamaguchi T AU - Fukamachi S AU - Sugata S TI - [On the leptospirosis occurred in a worker under construction of World Ocean Exposition in Okinawa Prefecture (author's transl)] LA - Jpn MH - Adult MH - Case Report MH - English Abstract MH - Human MH - Japan MH - Leptospirosis/*epidemiology MH - Male MH - Occupational Diseases/*epidemiology MH - Water Pollution PT - JOURNAL ARTICLE DA - 800514 DP - 1979 Jul TA - Sangyo Igaku PG - 366-9 SB - M CY - JAPAN IP - 4 VI - 21 JC - KK9 AA - Author EM - 8007 AB - A male worker, 29 years old, was engaged in construction work of World Ocean Exposition in Okinawa Perfecture, and was diagnosed as suffering from leptospirosis in September 1973. The leptospirosis was an acute infection caused by Leptospira hebdomadis. The parasite seemed to be transmitted to him by ingestion of food and drink contaminated with the urine and excreta of the reservoir animals in the unsanitary workshop and living environment in Okinawa district. This leptospirosis was determined as an occupational disease. PMID- 537222 CU - 88 EA - A SO - Sangyo Igaku 1979 Jul;21(4):366-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 80140902 AU - Awano H TI - [Indirect agglutination test of Leptospira using charcoal sensitized with antigen (author's transl)] LA - Jpn MH - Agglutination Tests/*methods MH - Antigens, Bacterial/*immunology MH - *Charcoal MH - Leptospira/*immunology RN - 16291-96-6 (Charcoal) PT - JOURNAL ARTICLE DA - 800523 DP - 1979 Jul IS - 0021-4930 TA - Nippon Saikingaku Zasshi PG - 693-5 CY - JAPAN IP - 4 VI - 34 JC - KHZ EM - 8007 PMID- 537163 SO - Nippon Saikingaku Zasshi 1979 Jul;34(4):693-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 80063230 AU - Jenkins EM AU - Harrington R Jr AU - Gbadamosi SG AU - Braye ET TI - Survey of leptospiral agglutinins in the sera of swine of southeastern Alabama. LA - Eng MH - Agglutinins/*analysis MH - Alabama MH - Animal MH - Comparative Study MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Support, U.S. Gov't, Non-P.H.S. MH - Swine/*immunology PT - JOURNAL ARTICLE DA - 800119 DP - 1979 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1019-21 SB - M CY - UNITED STATES IP - 7 VI - 40 JC - 40C AA - Author EM - 8003 AB - The occurrence of leptospirosis in swine of southeastern Alabama was determined. A total of 627 sera were tested, using the microscopic agglutination method, with live antigens of 12 serovars. Of the sera tested, 121 (19.3%) had a titer of 1:100 or greater to the serovars employed. The percentage distribution of sera with titers of greater than or equal to 1:100 among serovars most commonly reported was as follows: Leptospira interrogans serovars pomona, 3.8%; icterohaemorrhagiae, 3.3%; canicola, 1.6%; hardjo, 0.7%; and grippotyphosa, 0.16%. Of the less commonly recognized leptospiral serovars, the percentages reacting were as follows: ballum, 4.9%; autumnalis, 3.2%; pyrogenes, 1.1%; and bataviae, 0.4%. None of the sera reacted with antigen of serovars australis, tarassovi, or wolffi. PMID- 507487 SO - Am J Vet Res 1979 Jul;40(7):1019-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 80061452 AU - Terpstra WJ AU - Schoone GJ AU - Ligthart GS TI - Counterimmunoelectrophoresis in the diagnosis of human leptospirosis. LA - Eng MH - Agglutination Tests MH - Antigens, Bacterial MH - Counterimmunoelectrophoresis MH - Human MH - Leptospirosis/*diagnosis/immunology PT - JOURNAL ARTICLE DA - 800128 DP - 1979 Jul IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 285-90 SB - M CY - GERMANY, WEST IP - 2-3 VI - 244 JC - Y52 AA - Author EM - 8003 AB - Counterimmunoelectrophoresis (CIE) was applied on sera from patients with leptospirosis caused by leptospires from different serogroups and on sera from a control group. The CIE using an antigen prepared from a single leptospira strain agreed with the microscopic agglutination test using a battery of different antigens in 91% of the leptospirosis sera. CIE was sensitive and specific, comparatively easy to perform, used little amounts of serum and antigen, gave rapid results and allowed the examination of large numbers of specimens at a time. PMID- 506550 CU - 90 SO - Zentralbl Bakteriol [Orig A] 1979 Jul;244(2-3):285-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 90055770 AU - Stavri D AU - Moldoveanu G TI - Cross-reacting antigens among leptospires. LA - Eng MH - Antigens, Bacterial/*analysis MH - Cross Reactions MH - Leptospira/*immunology RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 891206 DP - 1979 Jul-Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 289-94 CY - ROMANIA IP - 3-4 VI - 38 JC - 8EM EM - 9002 PMID- 401010 CU - 91 NP - X SO - Arch Roum Pathol Exp Microbiol 1979 Jul-Dec;38(3-4):289-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 80049380 AU - Leman AD AU - Hurtgen JP AU - Hilley HD TI - Influence of intrauterine events on postnatal survival in the pig. LA - Eng MH - Abnormalities/veterinary MH - Animal MH - Animals, Newborn/*physiology MH - Birth Order MH - Birth Weight MH - Female MH - Fetal Death/epidemiology/veterinary MH - Fetus/*physiology MH - Hog Cholera/congenital MH - Leptospirosis/congenital/veterinary MH - Litter Size MH - Maternal-Fetal Exchange MH - Ovulation MH - Pregnancy MH - Swine/*physiology MH - Swine Diseases/congenital/epidemiology MH - Tremor/congenital/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 800128 DP - 1979 Jul IS - 0021-8812 TA - J Anim Sci PG - 221-4 SB - M CY - UNITED STATES IP - 1 VI - 49 JC - HC7 EM - 8003 RF - 25 PMID- 387692 CU - 90 SO - J Anim Sci 1979 Jul;49(1):221-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 80052175 AU - Hampy B AU - Pence DB AU - Simpson CD TI - Serological studies on sympatric Barbary sheep and mule deer from Palo Duro Canyon, Texas. LA - Eng MH - Anaplasmosis/epidemiology/immunology MH - Animal MH - Antibodies/*analysis MH - Bluetongue/epidemiology/immunology MH - Bovine Virus Diarrhea-Mucosal Disease/epidemiology/immunology MH - Brucellosis/epidemiology/immunology/veterinary MH - Cattle MH - Coccidioidomycosis/epidemiology/immunology/veterinary MH - Deer/*immunology MH - Infectious Bovine Rhinotracheitis/epidemiology/immunology MH - Leptospirosis/epidemiology/immunology/veterinary MH - Sheep/*immunology MH - Texas MH - Vesicular Stomatitis-Indiana Virus/immunology PT - JOURNAL ARTICLE DA - 800128 DP - 1979 Jul IS - 0090-3558 TA - J Wildl Dis PG - 443-6 SB - M CY - UNITED STATES IP - 3 VI - 15 JC - KEM AA - Author EM - 8003 AB - Sera were collected from 12 Barbary sheet (Ammotragus lervia) and 11 mule deer (Odocoileus hemionus) occupying sympatric ranges in Palo Duro Canyon, Texas. These were tested for leptospirosis, brucellosis, bovine virus diarrhea, anaplasmosis, vesicular stomatitis, bluetongue (BT), epizootic hemorrhagic disease (EHD), infectious bovine rhinotracheitis (IBR), and coccidioidomycosis. Serologic reactors were found to IBR in 3 Barbery sheep, BT in 6 Barbary sheep and 6 mule deer and EHD in 3 Barbary sheep and 4 mule deer. Possible ramifications of evidence for these diseases in wild herbivore populations in this area are discussed. PMID- 228088 CU - 93 SO - J Wildl Dis 1979 Jul;15(3):443-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 80000039 AU - Mazzonelli J AU - Jelambi F AU - Alvarez E AU - de la Canal H AU - Nava BO TI - [Prospective studies of porcine leptospirosis in organized farms of Venezuela] LA - Spa MH - Animal MH - English Abstract MH - Leptospirosis/*epidemiology/veterinary MH - Swine MH - Swine Diseases/*epidemiology MH - Venezuela PT - JOURNAL ARTICLE DA - 791121 DP - 1979 Jul IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 60-71 CY - UNITED STATES IP - 1 VI - 87 JC - AGG EM - 8001 RO - M:MYA PMID- 157763 LR - 810731 CU - 92 TT - Estudio prospectivo de la leptospirosis porcina en granjas organizadas de Venezuela. EA - A SO - Bol Oficina Sanit Panam 1979 Jul;87(1):60-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 80061453 AU - Adler B AU - Faine S TI - Serological cross-reactions of leptospiral lipopolysaccharide (F4) antigen. LA - Eng MH - *Antigens, Bacterial MH - Cross Reactions MH - Epitopes MH - Hemagglutination Tests MH - Leptospira/*immunology MH - Lipopolysaccharides MH - Pronase PT - JOURNAL ARTICLE DA - 800128 DP - 1979 Jul IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 291-301 SB - M CY - GERMANY, WEST IP - 2-3 VI - 244 JC - Y52 AA - Author EM - 8003 AB - The serological specificity of leptospiral lipopolysaccharide (F4) antigen was examined by the technique of passive haemagglutination. F4 extracted from leptospiral serovars representative of several different serogroups showed wide cross reaction between serovars, including numerous one-way (non-reciprocal) reactions. The pattern of cross reaction was different to that of the standard leptospiral classification scheme. PMID- 92115 CU - 95 SO - Zentralbl Bakteriol [Orig A] 1979 Jul;244(2-3):291-301 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 80060417 TI - Industrial injuries to cover leptospirosis [news] LA - Eng MH - Animal MH - Great Britain MH - Human MH - Leptospirosis/*economics MH - Occupational Diseases/*economics MH - *Workers' Compensation PT - NEWS DA - 800124 DP - 1979 Jun 16 IS - 0042-4900 TA - Vet Rec PG - 538 SB - M CY - ENGLAND IP - 24 VI - 104 JC - XBS EM - 8003 RO - M:LBR PMID- 159536 LR - 800506 CU - 92 NI - A SO - Vet Rec 1979 Jun 16;104(24):538 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 80129951 AU - Durfee PT AU - Presidente PJ TI - Experimental infections of brush-tailed possums, common wombats and water rats with Leptospira interrogans serovars balcanica and hardjo. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Kidney/pathology MH - Leptospira interrogans/immunology/*pathogenicity MH - Leptospirosis/immunology/microbiology/pathology/*veterinary MH - *Marsupialia MH - *Opossums MH - Rodent Diseases/*microbiology MH - Rodentia PT - JOURNAL ARTICLE DA - 800425 DP - 1979 Jun IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 231-40 SB - M CY - AUSTRALIA IP - 3 VI - 57 JC - 9FW AA - Author EM - 8006 AB - Of 12 brush-tailed possums (Trichosurus vulpecula) inoculated with Leptospira interrogans serovar balcanica 11 developed migroagglutination (MA) antibody to jardjo antigen by 14 days postincubation (PI). Leptospiruria was observed in 2 possums 117 to 145 days PI. Of 6 possums inoculated with serovar hardjo 4 developed low short-lived titres by day 18 PI. Two of 3 wombats (Vombatus ursinus) inoculated with balcanica had high MA titres (greater than or equal to 1:128) by day 16 PI and leptospiruria occurred by day 16. One wombat inoculated with hardjo developed a low MA titre. Low transitory MA titres to hardjo were found in 1 of 3 water rats (Hydromys chrysogaster) after inoculation with balcanica and 1 of 2 given hardjo. Histopathological examination of kidneys revealed mild to moderately severe focal interstitial nephritis in 4 of 8 possums, in 2 wombats and in 2 water rats following experimental infection with balcanica. Similar lesions were observed in 2 of 4 possums, 1 wombat and 2 water rats following experimental infection with hardjo. PMID- 533478 SO - Aust J Exp Biol Med Sci 1979 Jun;57(3):231-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 80071300 AU - Carlos RS AU - Medina CS AU - Dumag PU AU - Topacio TM Jr TI - Serological incidence of leptospirosis and leptospiral serotypes among livestock farms. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Comparative Study MH - Horse Diseases/*diagnosis MH - Horses MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis/*veterinary MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 800226 DP - 1979 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 61-5 SB - M CY - TAIWAN IP - 1 VI - 6 JC - GTK EM - 8004 PMID- 511443 SO - Int J Zoonoses 1979 Jun;6(1):61-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 80071297 AU - Everard CO AU - Cazabon EP AU - Dreesen DW AU - Sulzer CR TI - Leptospirosis in dogs and cats on the Island of Trinidad: West Indies. LA - Eng MH - Agglutination Tests MH - Animal MH - Cat Diseases/diagnosis/*epidemiology MH - Cats MH - Dog Diseases/diagnosis/*epidemiology MH - Dogs MH - Leptospirosis/diagnosis/epidemiology/*veterinary MH - Trinidad and Tobago PT - JOURNAL ARTICLE DA - 800226 DP - 1979 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 33-40 SB - M CY - TAIWAN IP - 1 VI - 6 JC - GTK AA - Author EM - 8004 AB - Confirming previous observations on dog populations in other parts of the world, notably Japan, the Philippine Islands, and some countries in South America, we found that a high percentage of dogs in Trinidad are infected with organisms from many serogroups of Leptospira. Serogroups Canicola and Icterohaemorrhagiae were most commonly found. Ten isolates obtained from 50 kidneys from stray dogs (20% infectivity rate) were typed as portland-vere (six) and canicola (two) of the Canicola serogroup, copenhageni of the Icterohaemorrhagiae serogroup (one), and georgia in the Hebdomadis serogroup (one). To the best of our knowledge, this is the first record of a serotype in the Hebdomadis serogroup being isolated from a dog. A cat isolation was identified as canicola. Serological results showed that 55% or more of stray dogs had been exposed as opposed to only 12.5% of the cats examined. Serogroups Canicola, Icterohaemorrhagiae and Hebdomadis are found most frequently in dogs, cats, mongooses, and man in Trinidad. PMID- 511442 CU - 88 SO - Int J Zoonoses 1979 Jun;6(1):33-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 80061428 AU - Schonberg A TI - Antibodies against Leptospira biflexa serotypes patoc and sao paulo in pigs: possible occurrence and importance for the intracutaneous test for leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Diagnosis, Differential MH - Intradermal Tests MH - Leptospira/classification/*immunology MH - Leptospirosis/diagnosis/*veterinary MH - Serotyping MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 800119 DP - 1979 Jun IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 45-9 SB - M CY - GERMANY, WEST IP - 1 VI - 244 JC - Y52 AA - Author EM - 8003 AB - Leptospirin for the diagnosis of leptospirosis by an intracutaneous test contains antigenic material from 5 pathogenic Leptospira serotypes (10). During experiments with rabbits and pigs, leptospirin was injected into 6 pigs which had been infected artificially with apathogenic Leptospira biflexa serotypes patoc and sao paulo. Three out of the 6 pigs showed a positive leptospirin reaction (11). This interfering reaction in animals having been infected with apathogenic L. biflexa was the reason to investigate the occurrence of biflexa antibodies in pigs from different areas in Germany by the microscopic agglutination. None of the 854 pigs showed biflexa antibodies producing a 50% agglutination at a serum dilution of 1:100. If at all, pigs may become infected naturally by L. biflexa; this apparently seems to be a rare incident. An impairment of the diagnostic value of leptospirin by L. biflexa antibodies can be excluded. PMID- 506540 CU - 90 SO - Zentralbl Bakteriol [Orig A] 1979 Jun;244(1):45-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 80059894 AU - van Heukelem HA AU - de Geus A AU - Thijs LG TI - Leptospirosis acquired in Surinam. LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Netherlands/ethnology MH - Suriname MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 800128 DP - 1979 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 301-4 SB - M CY - NETHERLANDS IP - 2 VI - 31 JC - WGJ AA - Author EM - 8003 AB - A case of leptospirosis seen in the Netherlands but acquired in Surinam is described. Marked jaundice, disturbance of renal function, a first degree atrioventricular block and pancreatic irritation were observed. PMID- 505561 CU - 88 SO - Trop Geogr Med 1979 Jun;31(2):301-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 80059889 AU - Myers DM AU - Varela-Diaz VM TI - The occurrence of leptospiral antibodies in rural inhabitants of Argentina. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agglutinins/analysis MH - Antibodies, Bacterial/*analysis MH - Argentina MH - Child MH - Child, Preschool MH - Female MH - Human MH - Leptospira/*immunology MH - Male MH - Middle Age MH - Rural Population PT - JOURNAL ARTICLE DA - 800128 DP - 1979 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 269-74 SB - M CY - NETHERLANDS IP - 2 VI - 31 JC - WGJ AA - Author EM - 8003 AB - Sera collected during surveys of presumably healthy rural inhabitants of the Provinces of Corrientes and Neuquen, Argentina, were examined for serological evidence of leptospirosis. Significant antibody levels (1:100 or greater) were found in 8.7 per cent of 1,029 sera from residents of Corrientes Province. The most frequent reactions occurred against the serotypes australis, hebdomadis group, pomona, and icterohaemorrhagiae. The predominance of antibodies to the Australis group in the country is new and suggests the emergence of leptospirosis in an unrecognized animal reservoir host. Out of 706 sera collected from rural school students and sera from 71 adults in the Province of Neuquen, only 4 (0.5%) showed leptospiral agglutinin in the microscopic agglutination test and these were only at a 1:100 serum dilution. The higher percentage of reactors in the Corrientes population appears to reflect a more favorable environment and a greater risk of infection. PMID- 505558 SO - Trop Geogr Med 1979 Jun;31(2):269-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 80059888 AU - Dikken H AU - Kmety E AU - De Geus A AU - Timmer VE TI - A new leptospiral serovar in the Australis serogroup. LA - Eng MH - Adult MH - Human MH - Leptospira/*classification MH - Male MH - Nomenclature MH - Serotyping PT - JOURNAL ARTICLE DA - 800128 DP - 1979 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 263-8 SB - M CY - NETHERLANDS IP - 2 VI - 31 JC - WGJ AA - Author EM - 8003 AB - A new serovar in the Australis serogroup is described after parallel investigations by the "classical" comparative cross-agglutinin absorption test method and by a method derived from factor analysis. The serovar name ramisi with reference strain Musa is proposed. PMID- 505557 SO - Trop Geogr Med 1979 Jun;31(2):263-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 79253933 AU - Bishop L AU - Strandberg JD AU - Adams RJ AU - Brownstein DG AU - Patterson R TI - Chronic active hepatitis in dogs associated with leptospires. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - *Dog Diseases/etiology/pathology MH - Dogs MH - Female MH - Hepatitis, Animal/*etiology/pathology MH - Kidney/pathology MH - Leptospira interrogans/immunology MH - Leptospirosis/complications/pathology/*veterinary MH - Liver/pathology MH - Male MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE DA - 791017 DP - 1979 Jun IS - 0002-9645 TA - Am J Vet Res PG - 839-44 SB - M CY - UNITED STATES IP - 6 VI - 40 JC - 40C AA - Author EM - 7912 AB - Chronic active hepatitis was diagnosed in five American Foxhounds from one kennel. Spirochetes were demonstrated in the liver in four of the dogs. A rising titer to Leptospira interrogans serovar grippotyphosa was found in the fifth dog, although spirochetes were not demonstrated in tissues. A serologic survey at the kennel revealed evidence of exposure of 6 of 13 dogs to grippotyphosa. This is the first report of an association between chronic active hepatitis leptospiral infection in any species. PMID- 475136 SO - Am J Vet Res 1979 Jun;40(6):839-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 79231403 AU - Bugl G AU - von Benten C TI - [Serological study of Leptospira antibodies in mares after abortion] LA - Ger MH - Abortion, Veterinary/*diagnosis MH - Animal MH - Antibodies, Bacterial/*analysis MH - English Abstract MH - Female MH - Horse Diseases/*diagnosis MH - Horses MH - Leptospira/*immunology MH - Leptospirosis/veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 790925 DP - 1979 Jun 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 209-11 CY - GERMANY, WEST IP - 11 VI - 92 JC - 9Q8 EM - 7911 PMID- 464998 CU - 84 TT - Serologische Untersuchung auf Leptospiren-Antikorper bei Stuten nach Abort. EA - A SO - Berl Munch Tierarztl Wochenschr 1979 Jun 1;92(11):209-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 80016505 AU - Petrov EM AU - Chernukha YG TI - Leptospires colonial variations. LA - Eng MH - Antigens, Bacterial MH - Bacteriological Techniques MH - Leptospira/*immunology MH - Variation (Genetics) MH - Virulence PT - JOURNAL ARTICLE DA - 791128 DP - 1979 Jun IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 511-21 SB - M CY - GERMANY, WEST IP - 4 VI - 243 JC - Y52 AA - Author EM - 8001 AB - Six of 12 relatively freshly isolated and museum strains representing serovars mozdok, monjakov, kazakhstanica I and patoc were heterogeneous in colonia morphology. Recloned colonial variants of one and the same heterogeneous population did not exhibit any differences in antigenic properties in cross reactions of microagglutination and absorption of agglutinins. Along with it among the clones with various colonial types of the two relatively freshly isolated strains of serovar mozdok distinctions in virulence (LD50) for hamsters were marked. Moreover for the clones one of them differences in the level of renal infection (ID50) and in morphology of the cells (hooked and straight) were found. In a solid Tween-80 albumin medium in populations of two colonial variants (serovars monjakov and kazakhstanica I) colonial mutants appeared without any changes in antigenic properties, virulence and cell morphology with frequency of 10-9-10-8 per one bacterium per one generation. PMID- 384719 CU - 90 SO - Zentralbl Bakteriol [Orig A] 1979 Jun;243(4):511-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 79228003 AU - Litvin VIu AU - Karaseva EV AU - Karulin BE TI - [Leptospira distribution in the soil of a natural focus of the infection (an attempt at the radioisotopic labelling of infected voles)] LA - Rus MH - Animal MH - Cobalt Radioisotopes MH - Comparative Study MH - *Disease Reservoirs MH - English Abstract MH - Female MH - Isotope Labeling/methods MH - Leptospira/*pathogenicity MH - Leptospirosis/*microbiology MH - Male MH - Microtinae/*microbiology MH - Phosphorus Radioisotopes MH - Rodent Diseases/*microbiology MH - Rodentia/*microbiology MH - *Soil Microbiology MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 790925 DP - 1979 Jun IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 74-9 SB - M CY - USSR IP - 6 JC - Y9O AA - Author EM - 7911 AB - The mass radioisotope (32P) labelling of all tundra voles excreting Zeptospira, infected urine was carried out over the area of 1 ha, and the results of the experiment analyzed by the method of planar coherent graphs, showed the irregular (spotted) distribution of "infected spots", i. e. soil patches contaminated by Zeptospira. The borders of individual small foci of infection did not coincide with the outlines of soil and vegetational divisions of the area. The spatial structure of the "extraorganismic" part of the Zeptospira population was originally formed by the carriers and thus determined by their mobility, their manner of using the territory. Later this structure was changed by selective elimination under the influence of living conditions for Zeptospira in the soil. The "infected spots", subjected to such selection, seem to be capable of constantly sustaining Zeptospira; the presence of these organisms is also due to the fact that they are regularly added into the soil with urine excreted by the carriers visiting the same spots of their territory. PMID- 380242 CU - 90 TT - Raspredelenie leptospir v pochve prirodnogo ochaga infektsii (opyt radioizotopnogo mecheniia zarazhennykh polevok). EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1979 Jun;(6):74-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 80078709 AU - Hodges RT AU - Thomson J AU - Townsend KG TI - Leptospirosis in pigs: the effectiveness of streptomycin in stopping leptospiruria. LA - Eng MH - Animal MH - Bacteriuria/*veterinary MH - Leptospira MH - Leptospirosis/drug therapy/*veterinary MH - Streptomycin/*therapeutic use MH - Swine MH - Swine Diseases/*drug therapy PT - JOURNAL ARTICLE DA - 800226 DP - 1979 Jun IS - 0048-0169 TA - N Z Vet J PG - 124-6 CY - NEW ZEALAND IP - 6 VI - 27 JC - OBZ EM - 8004 PMID- 292922 CU - 88 SO - N Z Vet J 1979 Jun;27(6):124-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 80078708 AU - Ho HF AU - Blackmore DK TI - Effect of chilling and freezing on survival of Leptospira interrogans serovar pomona in naturally infected pig kidneys. LA - Eng MH - Animal MH - *Freezing MH - Kidney/microbiology MH - Kidney Diseases/therapy/*veterinary MH - Leptospira interrogans/*growth & development MH - Leptospirosis/therapy/*veterinary MH - Swine MH - Swine Diseases/*therapy PT - JOURNAL ARTICLE DA - 800226 DP - 1979 Jun IS - 0048-0169 TA - N Z Vet J PG - 121-3 CY - NEW ZEALAND IP - 6 VI - 27 JC - OBZ EM - 8004 PMID- 292921 CU - 88 SO - N Z Vet J 1979 Jun;27(6):121-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 80078705 AU - Marshall RB AU - Broughton ES AU - Hellstrom JS TI - Protection of cattle against natural challenge with Leptospira interrogans serovar hardjo using a hardjo-pomona vaccine. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/immunology/*prevention & control MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 800226 DP - 1979 Jun IS - 0048-0169 TA - N Z Vet J PG - 114-6 CY - NEW ZEALAND IP - 6 VI - 27 JC - OBZ EM - 8004 PMID- 292918 CU - 88 SO - N Z Vet J 1979 Jun;27(6):114-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 79244077 AU - Wilks CR AU - Milner AR TI - Leptospirosis [letter] LA - Eng MH - Agricultural Workers' Diseases/*diagnosis/transmission MH - Animal MH - Cattle MH - Cattle Diseases/transmission MH - *Dairying MH - Human MH - Leptospirosis/*diagnosis/transmission/veterinary PT - LETTER DA - 791024 DP - 1979 May 5 IS - 0025-729X TA - Med J Aust PG - 396, 398 SB - M CY - AUSTRALIA IP - 9 VI - 1 JC - M26 EM - 7912 PMID- 470763 CU - 91 SO - Med J Aust 1979 May 5;1(9):396, 398 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 80011019 AU - Nazarova OG AU - Matsiuk VM TI - [Use of species specific leptospira antigens to prepare leptospiral erythrocyte diagnosticums] LA - Rus MH - Animal MH - *Antigens, Bacterial MH - English Abstract MH - Hemagglutination Tests MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Sheep/immunology MH - Species Specificity PT - JOURNAL ARTICLE DA - 791129 DP - 1979 May-Jun IS - 0201-8462 TA - Mikrobiol Zh PG - 273-8 CY - USSR IP - 3 VI - 41 JC - MY8 EM - 8001 PMID- 573364 CU - 85 TT - Primenenie rodospetsificheskikh antigenov leptospir dlia izgotovleniia leptospiroznykh eritrotsitarnykh diagnostikumov. EA - A SO - Mikrobiol Zh 1979 May-Jun;41(3):273-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 80022516 AU - Carpio MM AU - Iversen JO TI - A serological survey of Leptospira interrogans serotype pomona in Saskatchewan horses. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Horse Diseases/immunology MH - Horses/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/veterinary MH - Saskatchewan MH - Serotyping PT - JOURNAL ARTICLE DA - 791218 DP - 1979 May IS - 0008-5286 TA - Can Vet J PG - 127-30 CY - CANADA IP - 5 VI - 20 JC - CLS EM - 8002 PMID- 487358 SO - Can Vet J 1979 May;20(5):127-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 79205684 AU - Kiktenko VS AU - Volina EG AU - Sarukhanova LE TI - [Dynamics of Leptospira colony formation on solid nutrient media] LA - Rus MH - Culture Media MH - English Abstract MH - Leptospira/cytology/*growth & development MH - Serotyping MH - Species Specificity MH - Time Factors PT - JOURNAL ARTICLE DA - 790829 DP - 1979 May IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 87-90 SB - M CY - USSR IP - 5 JC - Y9O AA - Author EM - 7910 AB - The formation of Leptospira colonies on solid culture media varying in composition were studied. In all species of Leptospira 3 main periods of colony development were revealed, each of them having its characteristic morphological changes connected with the growth of the colony deeply into agar. PMID- 452782 CU - 90 TT - O dinamike formirovaniia kolomii leptospir na plotnykh pitatel'nykh sredakh. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1979 May;(5):87-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 79223084 AU - Taber LH AU - Feigin RD TI - Spirochetal infections. LA - Eng MH - Adolescence MH - Animal MH - Antibiotics/therapeutic use MH - Child MH - Diagnosis, Differential MH - Female MH - Human MH - Infant, Newborn MH - Leptospirosis/complications/diagnosis/transmission MH - Penicillin G/therapeutic use MH - Penicillins/therapeutic use MH - Pregnancy MH - Rat-Bite Fever/diagnosis/drug therapy MH - Relapsing Fever/diagnosis/drug therapy/transmission MH - *Spirochaetales Infections MH - Syphilis/drug therapy/etiology MH - Syphilis, Congenital/diagnosis/drug therapy/etiology MH - Treponemal Infections/diagnosis/drug therapy/prevention & control MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE PT - REVIEW DA - 790925 DP - 1979 May IS - 0031-3955 TA - Pediatr Clin North Am PG - 377-413 SB - A SB - M CY - UNITED STATES IP - 2 VI - 26 JC - OUM EM - 7911 RF - 56 PMID- 379781 CU - 90 SO - Pediatr Clin North Am 1979 May;26(2):377-413 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 79221108 AU - Kulik IL TI - [Basic types of functioning of parasitic systems in natural foci infections] LA - Rus MH - Animal MH - Arachnid Vectors/parasitology MH - *Disease Reservoirs MH - Disease Vectors/classification MH - English Abstract MH - Fleas/parasitology MH - Human MH - Insect Vectors/parasitology MH - Leishmaniasis/parasitology/transmission MH - Leptospirosis/parasitology/transmission MH - Parasitic Diseases/classification/*parasitology MH - Rabies/parasitology/transmission MH - Tularemia/parasitology/transmission MH - Zoonoses/parasitology/transmission PT - JOURNAL ARTICLE PT - REVIEW DA - 790927 DP - 1979 May-Jun IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 3-9 CY - USSR IP - 3 VI - 48 JC - M72 EM - 7911 RF - 55 PMID- 379566 CU - 90 TT - Osnovnye tipy funktsionirovaniia parazitarnykh sistem prirodno- ochagovykh infektsii. EA - A SO - Med Parazitol (Mosk) 1979 May-Jun;48(3):3-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 79205673 AU - Korenberg EI AU - Kovalevskii IuV AU - Kuzikov IV AU - Pchelkina AA AU - Busoedova NM TI - [Basic results of a survey of natural foci of human diseases in the Amur-Bureya portion of the Baikal-Amur mainline] LA - Rus MH - Animal MH - Animals, Wild/microbiology MH - Arachnid Vectors/microbiology MH - *Disease Reservoirs/veterinary MH - Disease Vectors MH - *Health Surveys MH - Human MH - Leptospirosis/epidemiology MH - *Railroads MH - Rickettsia Infections/epidemiology MH - Siberia MH - Swine MH - Swine Diseases/epidemiology MH - Ticks/microbiology MH - Tularemia/epidemiology MH - Yersinia pseudotuberculosis Infections/epidemiology MH - Yersinia Infections/epidemiology PT - JOURNAL ARTICLE DA - 790829 DP - 1979 May IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 34-8 SB - M CY - USSR IP - 5 JC - Y9O EM - 7910 PMID- 377865 CU - 90 TT - Osnovnye itogi razvdki prirodnykh ochagov boleznei cheloveka v Amur- Bureinskoi chasti BAM. SO - Zh Mikrobiol Epidemiol Immunobiol 1979 May;(5):34-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 80078692 AU - Hodges RT AU - Carter ME AU - Almand KB AU - Weddell W AU - Holland JT AU - Lewis SF AU - Lake DE TI - An evaluation of the semi-automated complement fixation test and the microscopic agglutination test for the serological diagnosis of bovine leptospirosis. LA - Eng MH - *Agglutination Tests/methods MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis/immunology MH - *Complement Fixation Tests/methods MH - Leptospirosis/diagnosis/*veterinary PT - JOURNAL ARTICLE DA - 800215 DP - 1979 May IS - 0048-0169 TA - N Z Vet J PG - 101-2 CY - NEW ZEALAND IP - 5 VI - 27 JC - OBZ EM - 8004 PMID- 292905 CU - 88 SO - N Z Vet J 1979 May;27(5):101-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 80019964 AU - Durfee PT AU - Presidente PJ TI - A sero-epidemiological study of Leptospira interrogans serovar Balcanica in four brush-tailed possum populations in Victoria, Australia. LA - Eng MH - Age Factors MH - Agglutination Tests MH - Animal MH - Animal Diseases/immunology MH - Animals/*immunology MH - Animals, Wild/*immunology MH - Antibodies/*analysis MH - Female MH - Leptospira/*immunology MH - Leptospirosis/veterinary MH - Male MH - Opossums/*immunology MH - Sex Factors PT - JOURNAL ARTICLE DA - 791129 DP - 1979 Apr IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 191-201 SB - M CY - AUSTRALIA IP - 2 VI - 57 JC - 9FW AA - Author EM - 8001 AB - The microscopic agglutination (MA) test was utilised to study the prevalence of antibodies to Leptospira interrogans serovar hardjo in 4 populations of brush-tailed possums (Trichosurus vulpecula). The overall antibody prevalence varied from 14% to 66%; however, the age distribution of MA test titres was remarkably similar in all 4 populations. Antibody prevalence was similar in both males and females and demonstrable antibodies were limited to sexually mature animals. The greater prevalence of high titres (greater than or equal to 1:128) in the 18- to 24-month age group suggested that primary infections were acquired at this age. The findings suggested that infection was maintained in possum populations by direct transmission, probably associated with breeding. Focal interstitial nephritis was observed in kidneys of possums greater than 18 months of age and was associated with MA titres to hardjo (P less than 0.001). Serovar balcanica was isolated from possum kidneys from 2 of these populations, suggesting that balcanica infections were responsible for most of the hardjo titres. However, agglutinin-absorption tests indicated that some possums may be infected with a leptospire more closely related to hardjo than to balcanica. PMID- 485985 CU - 90 SO - Aust J Exp Biol Med Sci 1979 Apr;57(2):191-201 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 80019963 AU - Durfee PT AU - Presidente PJ TI - A serological survey of Australian wildlife for antibodies to Leptospires of the Hebdomadis serogroup. LA - Eng MH - Animal MH - Animals/*immunology MH - Animals, Wild/*immunology/parasitology MH - Antibodies/*analysis MH - Australia MH - Kangaroos/immunology MH - Leptospira/*immunology MH - Marsupialia/immunology MH - Opossums/immunology PT - JOURNAL ARTICLE DA - 791129 DP - 1979 Apr IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 177-89 SB - M CY - AUSTRALIA IP - 2 VI - 57 JC - 9FW AA - Author EM - 8001 AB - A serological survey for antibodies to Leptospira interrograns serovar hardjo was conducted on 574 serum samples from 10 native and 4 introduced wildlife species in south-eastern Australia. The microscopic agglutination (MA) test was used, and titres to hardjo antigen were detected in 33.5% of 352 brushtailed possums (Trichosurus vulpecula) sampled in several areas of Victoria. Prevalence of reactors ranged from 14 to 66% in 4 populations examined intensively. Serovar balcanica was isolated from possums with hardjo antibodies from two different areas. Of 20 wombats Vombatus ursinus) examined in Victoria, antibodies to hardjo were found in sera from 4 and titres to Pyrogenes and Pomona serogroups were detected in another. Hardjo antibodies were demonstrated in sera from 13 of 19 rusa deer (Cervus timorensis). Negative MA test results to hardjo antigens were recorded in 55 mountain possums (T. caninus), 63 macropods (Macropus spp.), 17 water rats (Hydrmys chrysogaster), 39 fallow deer (Dama dama), 2 hog deer (Axis porcinus) and 2 water buffalo (Bubalus bubalus). No MA antibodies to any of 16 leptospiral serogroups were detected in 17 water rats tested. Kidneys were examined from 330 of these animals and focal interstitial nephritis suggestive of leptospirosis was found in kidneys of 63 of 169 T. vulpecula, 3 of 55 T. caninus, 12 of 18 V. ursinus, 6 of 22 Macropus spp., 9 of 16 H. chrysogaster, 5 of 11 C. timorensis and 3 of 39 D. dama. A statistical association between focal interstitial nephritis and MA antibodies to hardjo was found in T. vulpecula. PMID- 485984 CU - 90 SO - Aust J Exp Biol Med Sci 1979 Apr;57(2):177-89 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 80009515 AU - Fleming WJ AU - Nusbaum SR AU - Caslick JW TI - Serologic evidence of leptospirosis in woodchucks (Marmota monax) in central New York State. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Leptospira/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis/immunology/*veterinary MH - *Marmota MH - New York MH - *Rodentia PT - JOURNAL ARTICLE DA - 791121 DP - 1979 Apr IS - 0090-3558 TA - J Wildl Dis PG - 245-51 SB - M CY - UNITED STATES IP - 2 VI - 15 JC - KEM AA - Author EM - 8001 AB - Serum samples from 153 woodchucks (Marmota monax) from Tompkins County, New York, obtained in 1976 and 1977, were examined by plate agglutination tests for antibodies against five Leptospira antigens. Fourteen sera showed significant titers against either L. hardjo, L. icterohemorrhagiae and/or L. pomona. Reactions against L. hardjo were the most frequent. Woodchucks collected from two dairy farms with histories of bovine leptospirosis did not have a greater prevalence of antibodies than woodchucks collected from other locations. Each of two woodchucks experimentally-inoculated with L. hardjo developed titers to L. hardjo. Maximum titers occurred approximately 30 days post- inoculation. L. hardjo was not observed in urine specimens of these animals. PMID- 480515 CU - 90 SO - J Wildl Dis 1979 Apr;15(2):245-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 81280962 AU - Nicolescu M AU - Lola C TI - The serological diagnosis of domestic animals' leptospirosis by complement fixation test with antigens prepared in two different ways. LA - Eng MH - Animal MH - *Animals, Domestic MH - Antigens, Bacterial/*isolation & purification MH - Comparative Study MH - *Complement Fixation Tests MH - Leptospira/immunology MH - Leptospirosis/diagnosis/*veterinary RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 811028 DP - 1979 Apr-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 133-9 CY - ROMANIA IP - 2 VI - 38 JC - 8EM EM - 8112 PMID- 262508 CU - 91 SO - Arch Roum Pathol Exp Microbiol 1979 Apr-Jun;38(2):133-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 79204850 AU - Garett AL AU - Williamson CH TI - Leptospirosis in a dog. LA - Eng MH - Animal MH - Case Report MH - Dog Diseases/*diagnosis/therapy MH - Dogs MH - Female MH - Leptospirosis/diagnosis/therapy/*veterinary PT - JOURNAL ARTICLE DA - 790816 DP - 1979 Apr IS - 0042-4889 TA - Vet Med Small Anim Clin PG - 497-502 CY - UNITED STATES IP - 4 VI - 74 JC - XBO EM - 7910 PMID- 256372 CU - 87 SO - Vet Med Small Anim Clin 1979 Apr;74(4):497-502 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 80022722 AU - Sebek Z AU - Hodkova Z AU - Palicka P AU - Zitek K AU - Valova M TI - [First demonstration of natural foci of Leptospira pomona in the Czech Socialist Republic (author's transl)] LA - Cze MH - Animal MH - Antibodies, Bacterial/*analysis MH - Czechoslovakia MH - English Abstract MH - Leptospira/immunology/*isolation & purification MH - Mammals/immunology/*microbiology PT - JOURNAL ARTICLE DA - 791220 DP - 1979 Apr IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 155-62 CY - CZECHOSLOVAKIA IP - 3 VI - 28 JC - CSH EM - 8002 PMID- 158439 CU - 92 TT - Prvy dukaz prirodnich ohnisek Leptospira pomona v CSR. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1979 Apr;28(3):155-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [26 medline neighbors] UI - 79135059 AU - Berg HC AU - Turner L TI - Movement of microorganisms in viscous environments. LA - Eng MH - Escherichia coli/*physiology MH - Ficoll MH - Leptospira/*physiology MH - Methylcellulose MH - Movement MH - Structure-Activity Relationship MH - Support, U.S. Gov't, Non-P.H.S. MH - Viscosity PT - JOURNAL ARTICLE DA - 790516 DP - 1979 Mar 22 IS - 0028-0836 TA - Nature PG - 349-51 SB - M CY - ENGLAND IP - 5702 VI - 278 JC - NSC EM - 7907 PMID- 370610 CU - 90 SO - Nature 1979 Mar 22;278(5702):349-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 79248824 AU - Chabrolle JP AU - Derrida S AU - Mailloux M AU - Rossier A TI - [Leptospirosis in children: a not infrequent disease (author's transl)] LA - Fre MH - Adolescence MH - Antibodies, Bacterial/isolation & purification MH - Case Report MH - Child MH - English Abstract MH - Female MH - Human MH - Jaundice/etiology MH - Kidney Diseases/etiology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/complications/*epidemiology/transmission MH - Male MH - Meningitis/etiology MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 791017 DP - 1979 Mar 18-25 IS - 0037-1777 TA - Sem Hop PG - 601-7 SB - M CY - FRANCE IP - 1112 VI - 55 JC - ULD AA - Author EM - 7912 AB - A total of 14 cases of leptospirosis in children aged from 5 to 15 years, hospitalized in the Paris region, are reported. The polymorphe character of the disease is pointed out. The necessity for respecting a rigorous chronological order when requesting complementary examinations, which could confirm the diagnosis, is stressed. Domestic animals, team-mates, and while swimming at week-ends or during holidays, are potential sources or means of infection in the young. This justifies searching for leptospirosis in cases of unexplained fever, a pseudo-influenza syndrome, a meningitis which is mainly of the lymphocytic type, or more rarely, in cases of jaundice. Leptospirosis should be a disease well-known by the pediatrician. PMID- 224477 CU - 93 TT - La leptospirose de l'enfant, maladie non exceptionnelle. EA - A SO - Sem Hop 1979 Mar 18-25;55(1112):601-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 79183306 AU - But'ianov DD AU - Maksimovich VV TI - [Colostral immunity following simultaneous vaccination of dams against Aujesszky's disease and leptospirosis] LA - Rus MH - Animal MH - Colostrum/*immunology MH - Female MH - Leptospirosis/*veterinary MH - Pseudorabies/*prevention & control MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 790728 DP - 1979 Mar IS - 0042-4846 TA - Veterinariia PG - 36-8 CY - USSR IP - 3 JC - XCC EM - 7909 PMID- 442503 TT - Kolostral'nyi immunitet pri odnovremennoi vaktsinatsii matok protiv bolezni Aueski i leptospiroza. SO - Veterinariia 1979 Mar;(3):36-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 79172936 AU - Carleton O AU - Charon NW AU - Allender P AU - O'Brien S TI - Helix handedness of Leptospira interrogans as determined by scanning electron microscopy. LA - Eng MH - Comparative Study MH - Culture Media MH - Leptospira interrogans/*cytology/genetics MH - Microscopy, Electron, Scanning MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE DA - 790725 DP - 1979 Mar IS - 0021-9193 TA - J Bacteriol PG - 1413-6 SB - M CY - UNITED STATES IP - 3 VI - 137 JC - HH3 AA - Author EM - 7909 AB - Representative serovars and strains of the seven genetic groups of Leptospira interrogans, and two previously studied serovars, were all found to form exclusively right-handed helices as determined by scanning electron microscopy. No change in handedness occurred in cells grown in a minimal medium (Tween-80 albumin) compared to cells grown in a rich medium (rabbit serum). The right-handedness of the organisms was related to the evolution, cell wall structure, and the mechanism of motility of L. interrogans. PMID- 438122 SO - J Bacteriol 1979 Mar;137(3):1413-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 79172935 AU - Bromley DB AU - Charon NW TI - Axial filament involvement in the motility of Leptospira interrogans. LA - Eng MH - Cell Wall/physiology/ultrastructure MH - Leptospira/physiology MH - Leptospira interrogans/*ultrastructure MH - Movement MH - Mutation MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE DA - 790725 DP - 1979 Mar IS - 0021-9193 TA - J Bacteriol PG - 1406-12 SB - M CY - UNITED STATES IP - 3 VI - 137 JC - HH3 AA - Author EM - 7909 AB - Motility mutants of Leptospira interrogans serovar illini were isolated and analyzed by dark-field and electron microscopy. Mutants were obtained by screening for small colonies after nitrosoguanidine treatment. One class of mutants did not have hook- or spiral-shaped ends. In addition, the axial filaments from these mutants were not coiled. An analysis of revertants of two of the mutants in this class indicated that the mutations were pleiotropic with respect to motility, hook- and spiral-shaped ends, and axial filament coiling. We conclude that the axial filaments and the hook- and spiral-shaped ends are involved in L. interrogans motility. PMID- 438121 SO - J Bacteriol 1979 Mar;137(3):1406-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 79134668 AU - Pfaller M AU - Wray RC Jr TI - Leptospirosis and limb gangrene. Case report. LA - Eng MH - Arm/pathology MH - Case Report MH - Child, Preschool MH - Female MH - Gangrene/*complications MH - Human MH - Leg/pathology MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 790524 DP - 1979 Mar IS - 0026-6620 TA - Mo Med PG - 157-9 CY - UNITED STATES IP - 3 VI - 76 JC - NEW EM - 7907 PMID- 423880 SO - Mo Med 1979 Mar;76(3):157-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 79200370 AU - Murphy TJ TI - Leptospiral nephritis in a dog? LA - Eng MH - Animal MH - Case Report MH - Dog Diseases/*diagnosis MH - Dogs MH - Leptospirosis/diagnosis/*veterinary MH - Male MH - Nephritis/diagnosis/*veterinary PT - JOURNAL ARTICLE DA - 790829 DP - 1979 Mar IS - 0048-0169 TA - N Z Vet J PG - 32 CY - NEW ZEALAND IP - 3 VI - 27 JC - OBZ EM - 7910 PMID- 286959 CU - 88 SO - N Z Vet J 1979 Mar;27(3):32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 79223613 AU - Kennedy ND AU - Pusey CD AU - Rainford DJ AU - Higginson A TI - Leptospirosis and acute renal failure--clinical experiences and a review of the literature. LA - Eng MH - Adult MH - Case Report MH - Hemodialysis MH - Human MH - Kidney Failure, Acute/*etiology/therapy MH - Leptospirosis/*complications/diagnosis MH - Male MH - Middle Age MH - Parenteral Nutrition PT - JOURNAL ARTICLE DA - 790917 DP - 1979 Mar IS - 0032-5473 TA - Postgrad Med J PG - 176-9 CY - ENGLAND IP - 641 VI - 55 JC - PFX AA - Author EM - 7911 AB - About 50 cases of leptospirosis are diagnosed each year in the United Kingdom, with an overall mortality of 5%. Renal failure, in association with jaundice, is commonly held responsible for this figure. Over a period of 18 years, 6 cases of leptospirosis complicated by renal failure were treated at the Royal Air Force Renal Unit; there were 4 survivors. The 2 deaths occurred before the unit policy of daily haemodialysis and total parenteral nutrition, and were both from haemorrhagic complications. The authors believe that patients with leptospirosis and progressive renal impairment should be managed in renal units experienced in the management of the hypercatabolic patient, and that this should improve their prognosis. PMID- 111233 CU - 91 SO - Postgrad Med J 1979 Mar;55(641):176-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 79157254 AU - Olson JG AU - Irving GS AU - Bourgeois AL AU - Hodge FA AU - Van Peenen PF TI - Seroepidemiological evidence of infectious diseases in United States Marine Corps personnel, Okinawa, Japan, 1975--1976. LA - Eng MH - Adolescence MH - Adult MH - Female MH - Human MH - Japan MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - *Military Medicine MH - Scrub Typhus/*epidemiology/immunology MH - United States/ethnology PT - JOURNAL ARTICLE DA - 790626 DP - 1979 Mar IS - 0026-4075 TA - Mil Med PG - 175-6 CY - UNITED STATES IP - 3 VI - 144 JC - N1A EM - 7908 PMID- 107484 CU - 91 SO - Mil Med 1979 Mar;144(3):175-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 79119935 AU - Krauss N TI - [Neurological manifestations in leptospirosis] LA - Ger MH - Human MH - Leptospirosis/complications/*diagnosis MH - *Neurologic Manifestations MH - Parkinson Disease/etiology PT - JOURNAL ARTICLE DA - 790428 DP - 1979 Feb 28 IS - 0341-9835 TA - ZFA (Stuttgart) PG - 373-6 CY - GERMANY, WEST IP - 6 VI - 55 JC - XZ5 EM - 7906 PMID- 419827 TT - Neurologische Erscheinungen bei Leptospirose. SO - ZFA (Stuttgart) 1979 Feb 28;55(6):373-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [210 medline neighbors] UI - 79116010 AU - Beer K TI - [Leptospirosis] LA - Ger MH - Animal MH - Human MH - Leptospirosis/diagnosis/drug therapy/*transmission PT - JOURNAL ARTICLE DA - 790425 DP - 1979 Feb 20 IS - 0369-8394 TA - Schweiz Rundsch Med Prax PG - 260-1 CY - SWITZERLAND IP - 8 VI - 68 JC - SRM EM - 7906 PMID- 419080 CU - 84 TT - Leptospirosen. SO - Schweiz Rundsch Med Prax 1979 Feb 20;68(8):260-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 79120726 AU - Masedo Agirre S AU - Chernukha IuG TI - [Classification of Leptospira isolated in Peru] LA - Rus MH - Animal MH - Animals, Domestic/microbiology MH - Animals, Wild/microbiology MH - Antigens, Bacterial/analysis MH - Cross Reactions MH - English Abstract MH - Human MH - Leptospira/*classification/immunology/isolation & purification MH - Peru MH - Serotyping PT - JOURNAL ARTICLE DA - 790428 DP - 1979 Feb IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 77-81 SB - M CY - USSR IP - 2 JC - Y9O AA - Author EM - 7906 AB - Antigenic properties of 23 leptospira cultures isolated in Peru were studied by immunological absorption. Two new individual leptospira serovars were classified as huanuco with a reference strain M-4, representing a new Huanuco serological group, and san-martini with a reference strain CT-63 belonging to the Hebdomadis serological group. Besides for the first time in the American part of the world serovar budapest belonging to Icterohaemorrhagiae serological group was recorded; also the first finding of serovar pyrogenes of the pyrogenes serological group was certified. PMID- 419911 CU - 90 TT - K klassifikatsii leptospir, vydelennykh v Peru. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1979 Feb;(2):77-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 81062714 AU - Cinco Del Fabbro M AU - Dougan R AU - Jelincic A AU - Piacentini I TI - Evaluation of the use of "thermoresistant" antigen Patoc 1, in the diagnosis of human and animal leptospirosis. Preliminary report. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antigens, Bacterial MH - Cattle MH - Complement Fixation Tests MH - *Heat MH - Horses MH - Human MH - IgM MH - Leptospirosis/*diagnosis MH - Mercaptoethanol/pharmacology MH - Swine MH - Time Factors RN - 0 (Antigens, Bacterial) RN - 60-24-2 (Mercaptoethanol) PT - JOURNAL ARTICLE DA - 810226 DP - 1979 Jan 31 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 707-12 SB - M CY - ITALY IP - 6 VI - 57 JC - AKG AA - Author EM - 8104 AB - The macroagglutination test, according Mailloux, was investigated for its feasibility in the rapid diagnosis of human and animal leptospirosis. Suspected sera examinated by Mailloux test, were also examinated by Complement Fixation and Microagglutination; the results suggest that: Mailloux macroagglutination is the serological test of choice, for screening of animal and human sera, mostly if it is not needed to know the infecting serovar. PMID- 552823 CU - 91 SO - Boll Ist Sieroter Milan 1979 Jan 31;57(6):707-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 79104803 AU - Przytulski T AU - Porzeczkowska D TI - Polymorphism of blood serum amylase and transferrin and leptospirosis in Large White Polish pigs. LA - Eng MH - Amylases/*blood MH - Animal MH - Leptospirosis/enzymology/*veterinary MH - Polymorphism (Genetics) MH - Swine MH - Swine Diseases/*enzymology MH - Transferrin/*analysis PT - JOURNAL ARTICLE DA - 790425 DP - 1979 Jan-Feb IS - 0007-1935 TA - Br Vet J PG - 103-7 CY - ENGLAND IP - 1 VI - 135 JC - B5C EM - 7906 PMID- 761056 SO - Br Vet J 1979 Jan-Feb;135(1):103-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 80150179 AU - Gao XS AU - Xiong CS AU - Wu BA TI - [The leptospirocidal action of "Methimidol" and its metabolic process in vivo (author's transl)] LA - Chi MH - Animal MH - Dogs MH - English Abstract MH - Guinea Pigs MH - Leptospira/drug effects MH - Leptospirosis/*drug therapy MH - Mice MH - Microbial Sensitivity Tests MH - Rabbits PT - JOURNAL ARTICLE DA - 800530 DP - 1979 TA - Yao Hsueh Hsueh Pao PG - 577-86 CY - CHINA IP - 10 VI - 14 JC - 1PU EM - 8007 PMID- 539423 EA - A SO - Yao Hsueh Hsueh Pao 1979;14(10):577-86 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 80124999 AU - Everard CO AU - Fraser-Chanpong GM TI - Serological evidence of leptospirosis in Caribbean schoolchildren. LA - Eng MH - Adolescence MH - Antibodies, Bacterial/analysis MH - Bermuda MH - Child MH - Child, Preschool MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology MH - Male MH - West Indies PT - JOURNAL ARTICLE DA - 800417 DP - 1979 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 591-3 SB - M CY - ENGLAND IP - 5 VI - 73 JC - WBU EM - 8006 PMID- 531914 CU - 88 SO - Trans R Soc Trop Med Hyg 1979;73(5):591-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 80027433 AU - Morris JA AU - Orr HS TI - Immunity induced in hamsters vaccinated with a ribosome extract of Leptospira interrogans serogroup Icterohaemorrhagiae. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial MH - Bacterial Infections/*immunology MH - Hamsters MH - *Immunity MH - Leptospira interrogans/*immunology/ultrastructure MH - Nephritis/*immunology MH - Ribosomes/immunology MH - Vaccination PT - JOURNAL ARTICLE DA - 791220 DP - 1979 Jan IS - 0092-1157 TA - J Biol Stand PG - 81-7 SB - M CY - ENGLAND IP - 1 VI - 7 JC - HJD EM - 8002 PMID- 489623 SO - J Biol Stand 1979 Jan;7(1):81-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 79250149 AU - Everard CO AU - Fraser-Chanpong GM AU - Bhagwandin LJ AU - Ali S TI - Leptospirosis in patients from Grenada, West Indies. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Antibodies/analysis MH - Child MH - Child, Preschool MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Serotyping MH - West Indies PT - JOURNAL ARTICLE DA - 791026 DP - 1979 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 303-5 SB - M CY - ENGLAND IP - 3 VI - 73 JC - WBU AA - Author EM - 7912 AB - Evidence of leptospirosis in humans from Grenada, W.I., is reported here for the first time. Of 139 hospital patients with pyrexia of undetermined origin, 94 were jaundiced, and 16 (17%) of these were positive for hepatitis B antigen (HBsAg) and not examined further. 20 of the remaining 123 (16%) febrile patients were positive for leptospiral antibodies; 11 of them were current or recent cases. 25 of 182 (14%) afebrile out-patients showed evidence of previous exposure to leptospiral organisms. The most frequently encountered serogroups in the 45 seropositive in- and out-patients were Icterohaemorrhagiae (38%), Panama (24%) and Canicola (11%). PMID- 473326 CU - 88 SO - Trans R Soc Trop Med Hyg 1979;73(3):303-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 79250115 AU - Damude DF AU - Jones CJ AU - White HS AU - Myers DM TI - The problem of human leptospirosis in Barbados. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agglutination Tests MH - Agglutinins/analysis MH - Barbados MH - Child MH - Child, Preschool MH - Female MH - Human MH - Infant MH - Leptospira/immunology MH - Leptospirosis/diagnosis/*epidemiology/mortality MH - Male MH - Middle Age MH - Occupational Diseases/epidemiology MH - Rain MH - Retrospective Studies PT - JOURNAL ARTICLE DA - 791017 DP - 1979 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 169-77 SB - M CY - ENGLAND IP - 2 VI - 73 JC - WBU AA - Author EM - 7912 AB - The results of a retrospective study of human leptospirosis cases occurring in Barbados during the period 19-68-74, and of serological findings among high risk occupational groups, fever cases and health centre patients monitored for the disease during 1975-77, indicate that infection by serotype fort-bragg of the Autumnalis group is widespread in this Caribbean island. The occupational groups most affected are sanitation workers and sugar-cane workers. Results of serological tests conducted at the principle hospital are comparable with the results obtained by the microscopic agglutination reference test procedure conducted at the Pan American Zoonosis Centre (CEPANZO). PMID- 473305 CU - 90 SO - Trans R Soc Trop Med Hyg 1979;73(2):169-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 79249712 AU - Chaperon KM AU - Davis RB AU - Miller NG TI - Effect of a plasma cytotoxic factor in leptospirosis on platelets in vivo. LA - Eng MH - Animal MH - Blood Cell Count MH - *Blood Platelets MH - Blood Proteins MH - Cytotoxins/*blood MH - Dogs MH - Fibrinogen MH - Hamsters MH - Leptospirosis/*etiology MH - Platelet Aggregation MH - Spleen/ultrastructure MH - Time Factors PT - JOURNAL ARTICLE DA - 791026 DP - 1979 IS - 0049-3848 TA - Thromb Res PG - 975-80 SB - M CY - UNITED STATES IP - 6 VI - 14 JC - VRN EM - 7912 PMID- 473132 CU - 90 SO - Thromb Res 1979;14(6):975-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 79186522 AU - de Montis G AU - Chabrolle JP TI - [Adeno-cutaneo-mucous syndrome (letter)] LA - Fre MH - Child MH - Diagnosis, Differential MH - *Exocrine Glands MH - Human MH - Leptospirosis/diagnosis MH - *Mucous Membrane MH - Skin Diseases/*diagnosis MH - Syndrome PT - LETTER DA - 790725 DP - 1979 Jan IS - 0003-9764 TA - Arch Fr Pediatr PG - 82-3 SB - M CY - FRANCE IP - 1 VI - 36 JC - 71Q EM - 7909 PMID- 444006 CU - 91 TT - Le syndrome adeno-cutaneo-muqueux. SO - Arch Fr Pediatr 1979 Jan;36(1):82-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 79165578 AU - Gordon LM TI - Leptospira interrogans serovar hardjo infection of cattle. LA - Eng MH - Agglutination Tests MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/*epidemiology/immunology MH - Complement Fixation Tests MH - Mastitis, Bovine/epidemiology/immunology MH - Vaccination/veterinary MH - Weil's Disease/epidemiology/immunology/*veterinary PT - JOURNAL ARTICLE DA - 790626 DP - 1979 Jan IS - 0005-0423 TA - Aust Vet J PG - 1-5 SB - M CY - AUSTRALIA IP - 1 VI - 55 JC - 9IE AA - Author EM - 7908 AB - A survey of normal cattle in the Southern Victorian statistical divisions revealed that microscopic agglutination titres to L. hardjo occur at high frequency and are distributed throughout the cattle population. These titres are difficult to interpret as they may represent recent or old exposure, with or without disease. L. hardjo infection of dairy cattle was studied in 4 herds using the microscopic agglutination and complement-fixation tests. Statistical comparisons of individual titres obtained indicated that the sensitivity of the complement-fixation test was satisfactory for diagnostic purposes, but the test was unable to differentiate between current or past infections. PMID- 435201 CU - 88 SO - Aust Vet J 1979 Jan;55(1):1-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 79140490 AU - Nazarova OG TI - [Use of erythrocytic diagnosticum for the passive hemagglutination test in the diagnosis of leptospirosis] LA - Rus MH - Agglutinins/*isolation & purification MH - English Abstract MH - Erythrocytes/*immunology MH - Hemagglutination Tests/*methods MH - Human MH - Leptospirosis/*diagnosis/immunology PT - JOURNAL ARTICLE DA - 790524 DP - 1979 Jan IS - 0049-6804 TA - Vrach Delo PG - 104-6 CY - USSR IP - 1 JC - XLS EM - 7907 RO - M:MYA PMID- 425452 LR - 820729 TT - Primenenie eritrotsitarnogo diagnostikuma v RPGA dlia vyiavleniia leptospirozov. EA - A SO - Vrach Delo 1979 Jan;(1):104-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 79119290 AU - Akhmedov MM AU - Amaev KG AU - Salikhov IuS AU - Makhmudov MP TI - [Epizootiology of leptospirosis in animals] LA - Rus MH - Animal MH - Antibodies, Bacterial/analysis MH - Buffaloes MH - Cattle MH - Dagestan MH - Dogs MH - Horses MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Sheep MH - Swine PT - JOURNAL ARTICLE DA - 790425 DP - 1979 Jan IS - 0042-4846 TA - Veterinariia PG - 42-3 CY - USSR IP - 1 JC - XCC EM - 7906 PMID- 419667 CU - 88 TT - Epizootologiia leptospiroza zhivotnykh. SO - Veterinariia 1979 Jan;(1):42-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 80168006 AU - Bluszcz G AU - Ciszek Z TI - [Leptospirosis according to the data of the infectious disease department of the municipal hospital in Raciborz in the years 1966-1977] LA - Pol MH - Adolescence MH - Adult MH - Aged MH - Child MH - English Abstract MH - Female MH - History of Medicine, 20th Cent. MH - Hospital Records MH - Hospital Units MH - Hospitals, Municipal MH - Human MH - Leptospirosis/*epidemiology/history MH - Male MH - Middle Age MH - Poland MH - Urban Health MH - Weil's Disease/epidemiology PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 800616 DP - 1979 IS - 0033-2100 TA - Przegl Epidemiol PG - 515-8 CY - POLAND IP - 4 VI - 33 JC - Q8T EM - 8008 PMID- 396582 CU - 90 TT - Leptospirozt w materiale chorych oddzialu zakaznego w Raciborzu w latach 1966-1977. EA - A SO - Przegl Epidemiol 1979;33(4):515-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 79119291 AU - Bolotskii IA TI - [Methods of diagnosing leptospirosis in animals] LA - Rus MH - Animal MH - Comparative Study MH - Female MH - Hamsters MH - Immunologic Techniques MH - Leptospirosis/diagnosis/*veterinary MH - Mesocricetus MH - Serodiagnosis/veterinary MH - Swine MH - Swine Diseases/diagnosis PT - JOURNAL ARTICLE DA - 790425 DP - 1979 Jan IS - 0042-4846 TA - Veterinariia PG - 44-6 CY - USSR IP - 1 JC - XCC EM - 7906 PMID- 369106 CU - 90 TT - Metody diagnostiki leptospiroza zhivotnykh. SO - Veterinariia 1979 Jan;(1):44-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 81101195 AU - Cole JR Jr AU - Ellinghausen HC AU - Rubin HL TI - Laboratory diagnosis of leptospirosis of domestic animals. LA - Eng MH - Agglutination Tests/*veterinary MH - Animal MH - Antigens, Bacterial MH - Leptospira/immunology MH - Leptospirosis/diagnosis/*veterinary RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 810324 DP - 1979 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 189-95 CY - UNITED STATES IP - 83 JC - PY5 EM - 8105 PMID- 298915 CU - 91 SO - Proc Annu Meet U S Anim Health Assoc 1979;(83):189-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 81101194 AU - Tripathy DN AU - Hanson LE AU - Mansfield ME TI - Evaluation of serologic reactions in cattle following vaccination with multivalent leptospiral commercial bacterins and comparison of the microscopic agglutination (MA) antibody response by various laboratories. LA - Eng MH - Agglutination Tests/*veterinary MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Bacterial Vaccines/*immunology MH - Cattle/*immunology MH - Comparative Study MH - Evaluation Studies MH - Leptospira/*immunology MH - Support, Non-U.S. Gov't MH - Vaccination/veterinary RN - 0 (Antibodies, Bacterial) RN - 0 (Bacterial Vaccines) PT - JOURNAL ARTICLE DA - 810324 DP - 1979 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 180-8 CY - UNITED STATES IP - 83 JC - PY5 EM - 8105 PMID- 298914 CU - 91 SO - Proc Annu Meet U S Anim Health Assoc 1979;(83):180-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 81101193 AU - Ellinghausen HC Jr TI - Laboratory practices involving the leptospiral microscopic agglutination microtiter test. LA - Eng MH - Agglutination Tests/*veterinary MH - Animal MH - Antigens, Bacterial MH - Cattle MH - Female MH - Leptospira/immunology MH - Leptospirosis/diagnosis/*veterinary MH - Rabbits RN - 0 (Antigens, Bacterial) PT - JOURNAL ARTICLE DA - 810324 DP - 1979 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 163-79 CY - UNITED STATES IP - 83 JC - PY5 EM - 8105 PMID- 298913 CU - 91 SO - Proc Annu Meet U S Anim Health Assoc 1979;(83):163-79 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 82039421 AU - Pumarola Busquets A AU - Fernandez Nafria A AU - Esteban Velazquez E TI - [Leptospirosis in porcine livestock. Second serological survey in outbreaks of infectious abortion] LA - Spa MH - Abortion, Septic/*veterinary MH - Abortion, Veterinary/epidemiology/etiology MH - Animal MH - Disease Outbreaks/veterinary MH - English Abstract MH - Female MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Pregnancy MH - Spain MH - Swine MH - Swine Diseases/epidemiology/*immunology PT - JOURNAL ARTICLE DA - 811215 DP - 1979 Jan-Feb IS - 0034-8899 TA - Rev Sanid Hig Publica (Madr) PG - 51-5 CY - SPAIN IP - 1-2 VI - 53 JC - T41 EM - 8202 PMID- 263643 CU - 88 TT - Estudios sobre la leptospirosis del ganado porcino. Segunda encuesta serologica en explotaciones con aborto infeccioso. EA - A SO - Rev Sanid Hig Publica (Madr) 1979 Jan-Feb;53(1-2):51-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 81188157 AU - Zhu SP TI - [Analysis of 137 cases of leptospiral uveitis (author's transl)] LA - Chi MH - Adolescence MH - Adult MH - Child MH - China MH - Female MH - Human MH - Leptospirosis/*drug therapy/epidemiology MH - Male MH - Medicine, Chinese Traditional MH - Middle Age MH - Uveitis/*drug therapy/epidemiology PT - JOURNAL ARTICLE DA - 810709 DP - 1979 IS - 0412-4081 TA - Chung Hua Yen Ko Tsa Chih PG - 247-9 CY - CHINA IP - 4 VI - 15 JC - D9K EM - 8109 PMID- 122201 CU - 91 SO - Chung Hua Yen Ko Tsa Chih 1979;15(4):247-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 79250114 AU - Damude DF AU - Jones CJ AU - Myers DM TI - A study of leptospirosis among animals in Barbados W.I. LA - Eng MH - Agglutination Tests MH - Agglutinins/analysis MH - Animal MH - *Animals, Domestic MH - Animals, Wild MH - Barbados MH - Cattle MH - Cattle Diseases/epidemiology MH - Dogs MH - Haplorhini MH - Leptospira/immunology MH - Leptospirosis/epidemiology/*veterinary MH - Mice MH - Rats PT - JOURNAL ARTICLE DA - 791017 DP - 1979 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 161-8 SB - M CY - ENGLAND IP - 2 VI - 73 JC - WBU AA - Author EM - 7912 AB - Microscopic agglutination tests performed during 1971 and 1972 on Barbadian livestock showed positive serological reactions for leptospirosis as follows: cattle 51%, pigs 13%, sheep 18%, horses 64% and goats 19%. The serogroup Autumnalis predominated in all but horses in which the reactions to the Pyrogenes group appeared slightly higher. After the isolation of a strain of Leptospira serotype fort-bragg (Barbadian strain No. 119) of the Autumnalis serogroup in 1973, and its subsequent inclusion in our test battery of leptospiral antigens, high percentages of cattle, dogs, mongooses and man showed sero-positive reactions against the strain. Attention is called to the wide dissemination of the fort-bragg serotype on the island and to the role of rodents and the mongoose in its spread. 74 clinically affected Barbadian cattle from three herds were studied during 1975-76; 60 (81%) were serologically positive and nine different serogroups were represented. Predominant sero-positive reactions to Hebdomadis, Autumnalis, Ballum and Pyrogenes antigens were recorded. The highest titres were against Autumnalis, Hebdomadis and Pomona. Hebdomadis and Pomona serogroup antibodies may be due to many importations of cattle with those infections into Barbados. PMID- 112729 CU - 91 SO - Trans R Soc Trop Med Hyg 1979;73(2):161-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 80216423 AU - Yanagawa R AU - Shimono E AU - Shinjo EM TI - Isolation of antigenic variants from leptospiras grown in vitro and from heart blood of guinea pigs inoculated with a clonized strain of Leptospira. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis/genetics MH - Blood/*microbiology MH - Culture Media MH - Guinea Pigs MH - Immunodiffusion MH - Leptospira interrogans/growth & development/genetics/*immunology/isolation & purification MH - Precipitin Tests MH - Variation (Genetics) RN - 0 (Antigens, Bacterial) RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 800825 DP - 1979 IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 345-55 SB - M CY - GERMANY, WEST IP - 3 VI - 245 JC - Y52 AA - Author EM - 8010 AB - A clonized culture of Leptospira interrogans serovar copenhageni strain Shibaura (Cl-Shibaura) was inoculated into guinea pigs. The heart blood of the guinea pigs, obtained at the febrile stage and inoculated onto the solid serum medium containing the homologous immune serum, produced large and small colonies. The serological examinations revealed that the large colonies were found mainly to be the antigenic variants, while the small colonies were mostly the parent. The antigenic variants accounted for 16.4% of all the colonies from the blood of the guinea pigs infected with Cl-Shibaura, and for 1.2% of all the colonies from the blood of the guniea pigs infected with Cl-Shibaura, and for 1.2% of all the ll colonies. The serological examinations revealed that the large colonies were found mainly to be the antigenic variants, while the small colonies were mostly the parent. The antigenic variants accounted for 16.4% of all the colonies from the blood of the guniea pigs infected with Cl-Shibaura, and for 1.2% of all the colonies from the culture of Cl-Shibaura in the normal serum medium. Antigenic variants were also isolated in vitro from the culture of 2 other serovars. The fact that the frequency of the antigenic variants of leptospiras was higher in vivo than in vitro is discussed. PMID- 44789 CU - 94 SO - Zentralbl Bakteriol [Orig A] 1979;245(3):345-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 79160358 AU - Dikken H AU - Kmety E AU - de Geus A AU - Adinarayanan N AU - Timmer VE TI - Two new leptospira serovars belonging to the Hebdomadis serogroup. LA - Eng MH - Agglutination Tests MH - Cross Reactions MH - Human MH - Leptospira/*immunology MH - Leptospirosis/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 790629 DP - 1978 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 537-42 SB - M CY - NETHERLANDS IP - 4 VI - 30 JC - WGJ AA - Author EM - 7908 AB - Two new serovars in the leptospira Hebdomadis serogroup are described following parallel investigations by the "classical" comparative cross- agglutinin absorption test method and by a method derived from factor analysis. The serovar names nyanza with reference strain Kibos and dikkeni with reference strain Mannuthi are proposed. PMID- 749290 SO - Trop Geogr Med 1978 Dec;30(4):537-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 79129793 AU - Caldas EM AU - Sampaio MB AU - Costa E AU - Tishcenko LM TI - Patoc 1 and Rufino strains of Leptospira biflexa, as screening antigens in the diagnosis of leptospirosis. LA - Eng MH - Animal MH - *Antigens, Bacterial MH - Hemagglutination Tests MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 790516 DP - 1978 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 91-6 SB - M CY - TAIWAN IP - 2 VI - 5 JC - GTK AA - Author EM - 7907 AB - Patoc 1 and Rufino from L. complexo bifexa strains employed as screening antigen in the serologic diagnosis of liptospirosis in human and in six different animal species in comparison with a battery of 1.9 L complexo interrogans antigens, Patoc strain showed a 98.8% accordance in the sera agglutination tests, in humans; in animal it showed a low percentage of accordance in the sera agglutination tests in humans and in animals. PMID- 744706 SO - Int J Zoonoses 1978 Dec;5(2):91-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 79087870 AU - Corin RE AU - Boggs E AU - Cox CD TI - Enzymatic degradation of H2O2 by Leptospira. LA - Eng MH - Catalase/*metabolism MH - Comparative Study MH - Hydrogen Peroxide/metabolism MH - Leptospira/*enzymology MH - Leptospira interrogans/*enzymology MH - Peroxidases/*metabolism MH - Species Specificity MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE DA - 790328 DP - 1978 Dec IS - 0019-9567 TA - Infect Immun PG - 672-5 SB - M CY - UNITED STATES IP - 3 VI - 22 JC - GO7 AA - Author EM - 7905 AB - The enzymes responsible for reducing H2O2 were surveyed in 49 strains of Leptospira by using semiquantitative assays for catalase and peroxidase. The survey revealed a differential distribution of catalase and peroxidase activities between the two leptospiral complexes. The pathogenic Leptospira interrogans strains gave strong catalase and weak or negative peroxidase reactions. Conversely, the nonpathogenic Leptospira biflexa strains gave strong peroxidase and negative or weak catalase reactions. An intermediate group of four L. biflexa strains, which were isolated from mammals, fell into the high peroxidase, low or negative catalase group. One water isolate, H-23, gave strong reactions for both enzymes and was examined for virulence and in vitro growth parameters. Results indicate metabolic differences between pathogens and water forms in their abilities to reduce H2O2. PMID- 730380 SO - Infect Immun 1978 Dec;22(3):672-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 81112284 AU - Sivayoham S AU - Arumanayagam P TI - Health trends in sri lanka. LA - Eng MH - Communicable Diseases/epidemiology MH - *Health MH - Health Manpower MH - *Health Status MH - Human MH - Leptospirosis/epidemiology MH - Malaria/epidemiology MH - Poliomyelitis/epidemiology MH - Sri Lanka PT - JOURNAL ARTICLE DA - 810424 DP - 1978 Dec IS - 0009-0875 TA - Ceylon Med J PG - 139-48 CY - SRI LANKA IP - 4 VI - 23 JC - CY9 EM - 8106 PMID- 554738 CU - 90 SO - Ceylon Med J 1978 Dec;23(4):139-48 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 79248560 AU - Pumarola A AU - Gimeno de Sande A TI - [Leptospirosis in porcine live stock. 1st national serologic survey of pigs from apparently healthy stock and of their keepers] LA - Spa MH - Animal MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology/transmission/veterinary MH - Occupational Diseases/*epidemiology MH - Spain MH - Swine MH - Swine Diseases/*epidemiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 791026 DP - 1978 Nov-Dec IS - 0034-8899 TA - Rev Sanid Hig Publica (Madr) PG - 1425-33 CY - SPAIN IP - 11-12 VI - 52 JC - T41 EM - 7912 PMID- 754260 CU - 88 TT - Estudios sobre la leptospirosis del ganado porcino. Primera encuesta serologica nacional en cerdos procedentes de explotaciones aparentemente sanas y en el personal que los cuida. EA - A SO - Rev Sanid Hig Publica (Madr) 1978 Nov-Dec;52(11-12):1425-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 79109188 AU - Smith AW AU - Vedros NA AU - Akers TG AU - Gilmartin WG TI - Hazards of disease transfer from marine mammals to land mammals: review and recent findings. LA - Eng MH - Animal MH - Caliciviridae/isolation & purification MH - Dolphins/*microbiology MH - Leptospira/isolation & purification MH - Pinnipedia/*microbiology MH - Seals/microbiology MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 790425 DP - 1978 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1131-3 SB - M CY - UNITED STATES IP - 9 VI - 173 JC - HAV AA - Author EM - 7906 AB - In a 5-year study (1972-1977) of microbial agents isolated from both clinically normal and diseased marine mammals, it was shown that certain disease agents are widespread in a diversity of ocean populations and that some are also transmissible to a number of terrestrial mammal species. Leptospira interrogans serovar pomona has been isolated repeatedly from 2 species of pinnipeds (Zalophus californianus califonianus and Callorhinus ursinus). Some of the more important bacterial pathogens for land mammals that were isolated from wild marine mammals are Pseudomonas mallei, Clostridium chauvoei, C novyi, Neisseria mucosa var heidelbergensis, Klebsiella pneumoniae, Salmonella spp, and Pasteurella multocida. Numerous serotypes of viruses classified as caliciviruses were isolated from a variety of marine mammals. Some of these are known to infect several land mammal species including swine horses, and primates. For this reason., precautions should be taken to ensure that disease agents shed by captive marine mammals are not transmitted to susceptible terrestrial mammals, including animal handlers and other human beings. PMID- 738931 CU - 90 SO - J Am Vet Med Assoc 1978 Nov 1;173(9):1131-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 79090098 AU - Petrino MG AU - Doetsch RN TI - 'Viscotaxis', a new behavioural response of Leptospira interrogans (biflexa) strain B16. LA - Eng MH - Culture Media MH - Leptospira/*physiology MH - Movement MH - Viscosity PT - JOURNAL ARTICLE DA - 790313 DP - 1978 Nov IS - 0022-1287 TA - J Gen Microbiol PG - 113-7 SB - M CY - ENGLAND IP - 1 VI - 109 JC - I87 AA - Author EM - 7905 AB - When in a non-viscous environment and confronted with a viscous one, Leptospira interrogans (biflexa) strain B16 preferentially selected the latter. We have designated this positive response to a viscosity gradient as 'viscotaxis'. Using an originally designed experimental chamber, a pool of leptospires were faced with capillary tubes containing either polyvinylpyrrolidone (PVP) or N-2- hydroxyethylpiperazine-N'-2-ethanesulphonic acid (HEPES). Leptospires suspended in HEPES responded positively to 2% (w/v) PVP in capillaries, and migrated into them in large numbers in 1 h. No response was observed when the chamber and capillary tubes contained solutions of the same viscosity. As the viscosity of PVP was increased, a proportionally larger number of leptospires migrated into it. This newly observed aspect of leptospiral behaviour may have ecological significance. PMID- 731206 SO - J Gen Microbiol 1978 Nov;109(1):113-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 79070184 AU - Adler B AU - Faine S TI - Serological and protective-antibody responses of rabbits to leptospiral antigens. LA - Eng MH - Animal MH - Antibodies, Bacterial/*biosynthesis/immunology MH - Antigens, Bacterial/administration & dosage/*immunology MH - Female MH - Hamsters MH - IgG/biosynthesis MH - IgM/biosynthesis MH - Immunization MH - Injections, Intramuscular MH - Injections, Intravenous MH - Leptospira interrogans/*immunology MH - Leptospirosis/prevention & control MH - Male MH - Rabbits PT - JOURNAL ARTICLE DA - 790221 DP - 1978 Nov IS - 0022-2615 TA - J Med Microbiol PG - 401-9 SB - M CY - ENGLAND IP - 4 VI - 11 JC - J2N AA - Author EM - 7904 AB - The rabbit antibody response to leptospiral F4 antigen extracted from serovar pomona depended on the method of immunisation. Intravenous injection of whole leptospires stimulated F4 antibodies that were confined to the IgM class, but leptospires injected intramuscularly with adjuvant stimulated F4 antibodies in both the IgM and the IgM and the IgG classes. Both methods of immunisation stimulated agglutinins in both the IgM and IgG classes. F4 antigen in soluble form was immunogenci when injected intradermally with adjuvant, but not when given alone. The F4 antibodies were distinct from the agglutinins in that they did not protect hamsters from acute infection with homologous leptospires, nor did they kill leptospires in vitro although they reacted with leptospires. The hamster-protective capacity of rabbit sera depended on the level of agglutinin. PMID- 722782 SO - J Med Microbiol 1978 Nov;11(4):401-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 79070183 AU - Adler B AU - Faine S TI - The antibodies involved in the human immune response to leptospiral infection. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*biosynthesis/immunology MH - Hamsters MH - Hemagglutination Tests MH - Human MH - IgG/biosynthesis/immunology MH - IgM/immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/*immunology/prevention & control PT - JOURNAL ARTICLE DA - 790221 DP - 1978 Nov IS - 0022-2615 TA - J Med Microbiol PG - 387-400 SB - M CY - ENGLAND IP - 4 VI - 11 JC - J2N AA - Author EM - 7904 AB - Antibody responses were studied in human patients from whom leptospiral serovars--mainly pomona or hardjo--had been isolated and identified. The antibody to the polysaccharide F4 antigen belonged exclusively to the IgM class, even as late as 10 months after infection. Human sera cross-reacted widely with F4 antigen from heterologous serovars. The antibodies involved in leptospiral agglutination were mainly IgM, but some patients also produced IgG agglutinins. The titres of IgM agglutinins were higher than those of IgG agglutinins and persisted for many months, regardless of the presence or absence of IgG agglutinins. Both types of immunoglobulin from patients with serovar pomona infection protected hamsters against lethal infections with homologous leptospires. The hamster-protective capacity of human sera correlated well with agglutinin titres. Sera from patients infected with serovars other than pomona protected hamsters against challenge with pomona only if they contained agglutinins to that organism. PMID- 722781 SO - J Med Microbiol 1978 Nov;11(4):387-400 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 79050031 AU - Ohtaki C AU - Tomiyama T AU - Suzuki M AU - Hayakawa H AU - Kaga M TI - Leptospiral antibody and MLNS [letter] LA - Eng MH - *Antibodies, Bacterial MH - Child, Preschool MH - Diagnosis, Differential MH - Female MH - Human MH - Infant MH - Leptospira/*immunology MH - Leptospirosis/diagnosis MH - Male MH - Mucocutaneous Lymph Node Syndrome/diagnosis PT - LETTER DA - 790115 DP - 1978 Nov IS - 0022-3476 TA - J Pediatr PG - 896 SB - A SB - M CY - UNITED STATES IP - 5 VI - 93 JC - JLZ EM - 7903 PMID- 712509 CU - 91 SO - J Pediatr 1978 Nov;93(5):896 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 79183169 AU - Kramer TT TI - Immunity to bacterial infections. LA - Eng MH - Animal MH - Antibody Formation MH - Bacterial Infections/immunology/*veterinary MH - Bronchitis/veterinary MH - Brucellosis/veterinary MH - Cat Diseases/*immunology MH - Cats MH - Complement Pathway, Alternative MH - Dog Diseases/*immunology MH - Dogs MH - Enterotoxins/toxicity MH - Escherichia coli Infections/veterinary MH - Exotoxins/toxicity MH - Leptospirosis/veterinary MH - Macrophages/immunology MH - Salmonella Infections, Animal/immunology MH - T-Lymphocytes/*immunology MH - Tracheitis/veterinary MH - Tuberculosis/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 790725 DP - 1978 Nov IS - 0091-0279 TA - Vet Clin North Am PG - 683-95 SB - M CY - UNITED STATES IP - 4 VI - 8 JC - XBG EM - 7909 RF - 15 PMID- 375557 CU - 90 SO - Vet Clin North Am 1978 Nov;8(4):683-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 79156485 TI - Infertility in gilts and sows. LA - Eng MH - Animal MH - Eperythrozoonosis/complications/veterinary MH - Female MH - Infertility, Female/etiology/*veterinary MH - Influenza A Virus, Porcine MH - Leptospirosis/complications/veterinary MH - Orthomyxoviridae Infections/complications/veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*etiology MH - Vibrio Infections/complications/veterinary PT - JOURNAL ARTICLE DA - 790611 DP - 1978 Nov IS - 0362-8140 TA - Mod Vet Pract PG - 863-5 SB - M CY - UNITED STATES IP - 11 VI - 59 JC - NGO EM - 7908 PMID- 219327 CU - 96 NI - A SO - Mod Vet Pract 1978 Nov;59(11):863-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 79099929 AU - Sugiyama K AU - Yanagawa R TI - Inhibition of leptospiral agglutination by the nondialyzable delipidized serovar-specific main antigens of leptospiras. LA - Eng MH - *Agglutination MH - Antigens, Bacterial MH - Epitopes MH - Leptospira/*immunology MH - Lipids/analysis PT - JOURNAL ARTICLE DA - 790324 DP - 1978 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 261-4 SB - M CY - GERMANY, WEST IP - 2 VI - 242 JC - Y52 AA - Author EM - 7905 AB - Microscopic agglutination of leptospiras was inhibited by the homologous nondialyzable delipidized serovar-specific main (NDTM) antigens of leptospiras. The agglutination was not inhibited by the heterologous NDTM antigens. The results may indicate that the substance participating in the microscopic agglutination of leptospiras with antiserum is the NDTM antigens. PMID- 83754 CU - 95 SO - Zentralbl Bakteriol [Orig A] 1978 Nov;242(2):261-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 79099914 AU - Cinco M AU - Dougan R AU - Panfili E TI - The immunoglobulins response in rabbit to single antigenic factors of leptospira. Investigations with two serovars from saprophytic leptospira. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Antigens, Bacterial/*immunology MH - Epitopes MH - IgG/*biosynthesis MH - IgM/*biosynthesis MH - Leptospira/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 790324 DP - 1978 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 85-92 SB - M CY - GERMANY, WEST IP - 1 VI - 242 JC - Y52 AA - Author EM - 7905 AB - The agglutinating antibodies formed after immunization of rabbits with viable leptospira consist of 19S and 7S immunoglobulins. IgM and IgG are formed already earlier in the course of immunization. after a lapse of one month more IgG is found than IgM. The specificity of agglutination with the main antigenic factors is due mainly to IgG. PMID- 83752 CU - 95 SO - Zentralbl Bakteriol [Orig A] 1978 Nov;242(1):85-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 79088884 AU - Myers DM AU - Coltorti EA TI - Broadly reacting precipitating and agglutinating antigen of leptospirae. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis/immunology/isolation & purification MH - Cross Reactions MH - Epitopes MH - Hamsters MH - Immunodiffusion MH - Immunoelectrophoresis MH - Leptospira/*immunology/pathogenicity MH - Leptospirosis/immunology MH - Species Specificity PT - JOURNAL ARTICLE DA - 790313 DP - 1978 Nov IS - 0095-1137 TA - J Clin Microbiol PG - 580-90 SB - M CY - UNITED STATES IP - 5 VI - 8 JC - HSH AA - Author EM - 7905 AB - A saprophytic Leptospira biflexa strain of equine origin was found which cross-reacts with immune rabbit antisera to 14 pathogenic Leptospira interrogans serotypes. Sera from goats experimentally inoculated with the saprophyte showed multiple low-level cross- agglutination reactions against a battery of live L. interrogans serotypes. Sonically treated and saline-extracted suspensions of the L. biflexa strain and serotypes canicola, icterohaemorrhagiae, and pomona yielded a common precipitating protein antigen that was detected by immunodiffusion and immunoelectrophoresis with all of the antileptospiral sera examined. In cross-absorption and gel diffusion tests, the precipitinogen from each of the strains was shown to be identical. Formaldehyde treatments and heating at 100 degree C suggest that the cellular location of the common antigen is either somatic or subsurface, and Sephadex G-200 gel filtration enabled the isolation of the active fraction of the L. biflexa antigen. Monoprecipitin sera against the common antigen of L. biflexa were produced by immunizing rabbits with specific precipitates in agar. In gel diffusion and immunoelectrophoresis tests the antisera with each of the soluble antigens developed a single precipitin formation, and the antisera agglutinated formolized and heated whole-cell suspensions of serotypes canicola, icterohaemorrhagiae, and pomona at low dilutions. The soluble L. biflexa antigen was evaluated as an immunogen and in passive immunity tests for protection against death and kidney infection in hamsters. No cross-protection occurred when the hamsters were challenged with virulent leptospires. In contrast, the animals vaccinated or administered hamster immune serum before challenge died earlier than the control animals. PMID- 83327 CU - 95 SO - J Clin Microbiol 1978 Nov;8(5):580-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 79115880 AU - Cumming WJ AU - Thrush DC AU - Kenward DH TI - Bilateral neuralgic amyotrophy complicating Weil's disease. LA - Eng MH - Cervico-Brachial Neuralgia/*etiology MH - Human MH - Male MH - Middle Age MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 790428 DP - 1978 Oct IS - 0032-5473 TA - Postgrad Med J PG - 680-1 CY - ENGLAND IP - 636 VI - 54 JC - PFX AA - Author EM - 7906 AB - The case of a patient with leptospirosis (treated with trimethoprim) with late neurological complications manifesting as a bilateral plexus syndrome is described. The probable reasons for the continued weakness, in this patient, of the muscles supplied by the anterior interosseus nerve, despite improvement in the proximal muscles, are briefly discussed. PMID- 740594 SO - Postgrad Med J 1978 Oct;54(636):680-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 79056262 AU - Zeigermakher GA TI - [Leptospirosis caused by an association of different serotypes of Leptospira] LA - Rus MH - Acute Disease MH - Case Report MH - Human MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology MH - Male MH - Middle Age MH - Serotyping PT - JOURNAL ARTICLE DA - 790124 DP - 1978 Oct IS - 0038-5077 TA - Sov Med PG - 143-5 CY - USSR IP - 10 JC - UW7 EM - 7903 PMID- 715527 TT - O leptospiroze, vyzvannom assotsiatsiei leptospir razlichnykh serotipov. SO - Sov Med 1978 Oct;(10):143-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 79056253 AU - Barats SM AU - Levin IuL AU - Matkovskii BV TI - [Hyperbaric oxygenation in the treatment of icterohemorrhagic leptospirosis] LA - Rus MH - Adult MH - Atmosphere Exposure Chambers MH - Case Report MH - Drug Therapy, Combination MH - English Abstract MH - Human MH - *Hyperbaric Oxygenation MH - Kidney Failure, Acute/therapy MH - Male MH - Weil's Disease/*therapy PT - JOURNAL ARTICLE DA - 790124 DP - 1978 Oct IS - 0038-5077 TA - Sov Med PG - 125-8 CY - USSR IP - 10 JC - UW7 EM - 7903 PMID- 715519 TT - Giperbaricheskaia oksigenatsiia v lechenii ikterogemorragicheskogo leptospiroza. EA - A SO - Sov Med 1978 Oct;(10):125-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 79115154 AU - Ris DR AU - Hamel KL TI - The detection of Leptospirae in cattle urine. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Urine/*microbiology PT - JOURNAL ARTICLE DA - 790425 DP - 1978 Oct IS - 0048-0169 TA - N Z Vet J PG - 246, 255-6 CY - NEW ZEALAND IP - 10 VI - 26 JC - OBZ EM - 7906 PMID- 283338 CU - 88 SO - N Z Vet J 1978 Oct;26(10):246, 255-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 79044666 AU - Kahrs RF AU - Holmes DN AU - Poppensiek GC TI - Diseases transmitted from pets to man: an evolving concern for veterinarians. LA - Eng MH - Animal MH - *Animals, Domestic MH - Bites and Stings/epidemiology MH - Brucellosis/transmission/veterinary MH - Cat-Scratch Disease/transmission MH - Cats MH - Child MH - Dog Diseases/transmission MH - Dogs MH - Human MH - Larva Migrans, Visceral/transmission MH - Leptospirosis/transmission/veterinary MH - Leukemia Virus, Feline MH - Rabies/transmission/veterinary MH - Salmonella Infections, Animal/transmission MH - Scabies/transmission MH - Toxoplasmosis/transmission MH - Toxoplasmosis, Animal/transmission MH - United States MH - Veterinary Medicine MH - Zoonoses/*transmission PT - JOURNAL ARTICLE PT - REVIEW DA - 790124 DP - 1978 Oct IS - 0010-8901 TA - Cornell Vet PG - 442-59 SB - M CY - UNITED STATES IP - 4 VI - 68 JC - DRI AA - Author EM - 7903 AB - Pets are not a major source of human infections but they can transmit certain diseases to man. This transmission usually is complex, requiring close contact with pets or their excretions and frequently involves a breach of sound hygienic practice. In some instances, pathogens of animal origin are acquired inadvertently because infectivity can persist after evidence of gross contamination has gone. Veterinarians participate in controlling zoonotic diseases by encouraging rabies vaccination and hygienic treatment of pet feces and urine, by supporting community efforts toward responsible pet ownership and by advising on precautions for handling sick animals. It is recommended that veterinarians discourage the keeping of wild or exotic animals as pets and excess fondling of pets (particularly by children and pregnant women). Clients and kennel workers should be advised to use caution with animals that have aborted. RF - 65 PMID- 213237 CU - 93 SO - Cornell Vet 1978 Oct;68(4):442-59 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 79053718 AU - Marshall RB AU - Scrimgeour G TI - Schizophreniform psychosis associated with leptospirosis [letter] LA - Eng MH - Case Report MH - Human MH - Leptospirosis/*complications MH - Male MH - Schizophrenia/*etiology PT - LETTER DA - 790126 DP - 1978 Sep 13 IS - 0028-8446 TA - N Z Med J PG - 212-3 SB - M CY - NEW ZEALAND IP - 619 VI - 88 JC - OBQ EM - 7903 PMID- 280804 CU - 91 SO - N Z Med J 1978 Sep 13;88(619):212-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 79057447 AU - Ellis WA AU - Logan EF AU - O'Brien JJ AU - Neill SD AU - Ferguson HW AU - Hanna J TI - Antibodies to Leptospira in the sera of aborted bovine fetuses. LA - Eng MH - Abortion, Veterinary/*immunology MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle/immunology MH - Cattle Diseases/*immunology MH - Female MH - Fetus/*immunology MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 790126 DP - 1978 Sep 9 IS - 0042-4900 TA - Vet Rec PG - 237-9 SB - M CY - ENGLAND IP - 11 VI - 103 JC - XBS AA - Author EM - 7903 AB - Antibodies to Leptospira serotypes were detected in sera from 15 (6.9 per cent) of 218 aborted fetuses, but were not detected in the sera from 196 non-aborted fetuses. Fourteen (6.4 per cent) sera from the aborted fetuses had antibodies to strains belonging to the Hebdomadis serogroup and 1 (0.5 per cent) had antibodies to a strain belonging to the Icterohaemorrhagiae serogroup. These antibodies were predominantly immunoglobulin M whereas in the dams, antibodies belonged to both immunoglobulin M and G classes. PMID- 716168 SO - Vet Rec 1978 Sep 9;103(11):237-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 79092696 AU - Eknoyan G AU - Dillman RO TI - Renal complications of infectious diseases. LA - Eng MH - Antigen-Antibody Complex MH - Bacterial Infections/*complications MH - Cerebrospinal Fluid Shunts/adverse effects MH - Chickenpox/complications MH - Coxsackievirus Infections/complications MH - Endocarditis, Bacterial/complications MH - Glomerulonephritis/etiology MH - Hepatitis, Viral, Human/complications MH - Human MH - Infectious Mononucleosis/complications MH - Influenza/complications MH - Kidney Diseases/*etiology MH - Kidney Failure, Acute/etiology MH - Leprosy/complications MH - Leptospirosis/complications MH - Malaria/complications MH - Mumps/complications MH - Nephritis/etiology MH - Nephrotic Syndrome/etiology MH - Pneumococcal Infections/complications MH - Syphilis/complications MH - Syphilis, Congenital/complications MH - Tuberculosis, Renal MH - Virus Diseases/*complications PT - JOURNAL ARTICLE PT - REVIEW DA - 790313 DP - 1978 Sep IS - 0025-7125 TA - Med Clin North Am PG - 979-1003 SB - A SB - M CY - UNITED STATES IP - 5 VI - 62 JC - LU6 EM - 7905 RF - 229 PMID- 366299 CU - 90 SO - Med Clin North Am 1978 Sep;62(5):979-1003 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 79043716 AU - Kmety E AU - Bakoss P TI - [On the selection of antigens for microagglutination reaction in leptospiroses (author's transl)] LA - Slo MH - Agglutination Tests/*methods MH - Antigens, Bacterial/*immunology MH - English Abstract MH - Human MH - Leptospirosis/diagnosis/*immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 790126 DP - 1978 Sep IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 247-52 CY - CZECHOSLOVAKIA IP - 5 VI - 27 JC - CSH EM - 7903 PMID- 152156 CU - 92 TT - Kotazke vol'by antigenov do mikroaglutinacnej reakcie pri leptospirozach. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1978 Sep;27(5):247-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [209 medline neighbors] UI - 79037330 AU - Witczuk J TI - [Sporadic cases of leptospirosis] LA - Pol MH - Adult MH - Case Report MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology/transmission MH - Male MH - Middle Age MH - Poland MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 781227 DP - 1978 Aug 15 IS - 0043-5147 TA - Wiad Lek PG - 1169-72 CY - POLAND IP - 16 VI - 31 JC - XOA EM - 7902 PMID- 706372 CU - 88 TT - Sporadyczne przypadki leptospiroz. EA - A SO - Wiad Lek 1978 Aug 15;31(16):1169-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 78224738 AU - Munnich D AU - Bakondi M TI - [Severe leptospirosis treated successfully with amoxicillin and glycocorticoid] LA - Hun MH - Adult MH - Amoxicillin/*therapeutic use MH - Ampicillin/*analogs & derivatives MH - Case Report MH - Cholestasis/drug therapy MH - Drug Therapy, Combination MH - Human MH - Hyperbilirubinemia/drug therapy MH - Leptospirosis/*drug therapy MH - Male MH - Prednisolone/*therapeutic use PT - JOURNAL ARTICLE DA - 780929 DP - 1978 Aug 6 IS - 0030-6002 TA - Orv Hetil PG - 1967-8 CY - HUNGARY IP - 32 VI - 119 JC - OL8 EM - 7811 PMID- 673415 CU - 90 TT - Amoxycillinnel es glycocorticoiddal sikeresen kezelt sulyos leptospirosis. SO - Orv Hetil 1978 Aug 6;119(32):1967-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 79120752 AU - Baryshev PM AU - Kokovin IL TI - [1st isolation of serovar Sorex--Jalna leptospirae from humans] LA - Rus MH - Adolescence MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/analysis MH - Case Report MH - Cross Reactions MH - English Abstract MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*microbiology MH - Male MH - Septicemia/*microbiology PT - JOURNAL ARTICLE DA - 790425 DP - 1978 Aug IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 42-5 SB - M CY - USSR IP - 8 JC - Y9O AA - Author EM - 7906 AB - Leptospira strain "Patient No. 84", identical to the international standard of sorexjalna serovar, of Javanica serogroup was for the first time isolated on the 5th day of the disease from a patient suffering from leptospirosis in seeding his blood in Vervoort-Wolf's fluid medium. Antibodies heterologous against the strain isolated were also determined in the patient's blood on the 5th day. Their titre was 1 : 200(++), and they proved to react with leptospira of Cynopteri and Pomons serogroup. PMID- 742279 TT - O pervom vydelenii ot cheloveka leptospir serovara Sorex--Jalna. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1978 Aug;(8):42-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 79092973 AU - Borcic B AU - Kovacic H AU - Tvrtkovic N AU - Sebek Z AU - Aleraj B TI - [Myomorphous mammals as leptospirae reservoirs in the lowlands of SR Croatia (author's transl)] LA - Scr MH - Animal MH - Disease Reservoirs MH - *Disease Vectors MH - English Abstract MH - Leptospira/*isolation & purification MH - Rodentia/*microbiology MH - Yugoslavia PT - JOURNAL ARTICLE DA - 790313 DP - 1978 Aug IS - 0024-3477 TA - Lijec Vjesn PG - 465-70 CY - YUGOSLAVIA IP - 8 VI - 100 JC - L6C EM - 7905 PMID- 732504 TT - Misoliki sisavci kao rezervoari leptospira u nizinskim podrucjima SR Hrvatske. EA - A SO - Lijec Vjesn 1978 Aug;100(8):465-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 79030667 AU - Pupkevich-Diamant IaS AU - Rychnev VE TI - [Clinical aspects of sporadic cases of icterohemorrhagic leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Child MH - English Abstract MH - Female MH - Human MH - Jaundice/etiology MH - Kidney Diseases/etiology MH - Liver Diseases/etiology MH - Male MH - Weil's Disease/complications/*diagnosis PT - JOURNAL ARTICLE DA - 781229 DP - 1978 Aug IS - 0023-2149 TA - Klin Med (Mosk) PG - 101-10 CY - USSR IP - 8 VI - 56 JC - KW2 EM - 7902 PMID- 703198 TT - O klinike sporadicheskikh sluchaev ikterogemorragicheskogo leprospiroza. EA - A SO - Klin Med (Mosk) 1978 Aug;56(8):101-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 78244589 AU - Lewis J TI - The routine application of a microtechnique for the demonstration of leptospiral antibodies. LA - Eng MH - Agglutination Tests/methods MH - Antibodies, Bacterial/*analysis MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 781027 DP - 1978 Aug IS - 0022-2615 TA - J Med Microbiol PG - 355-8 SB - M CY - ENGLAND IP - 3 VI - 11 JC - J2N AA - Author EM - 7812 AB - The microtechnique of Galton et al. (1965) for the routine screening of blood samples for leptospiral antibodies was used to examine more than 8000 serum samples from animals that had aborted and from herds in which leptospiral antibodies had previously been demonstrated. The method gave consistently accurate results. In respect of ease and speed of performance, it was superior to the microscopic agglutination test and it required only minute volumes of serum and antigen suspension. Its most important advantage was that the agglutination reaction could be read directly on the plate, and the removal of samples for microscopical examination was therefore unnecessary. PMID- 682180 SO - J Med Microbiol 1978 Aug;11(3):355-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 78244588 AU - Ris DR AU - Hamel KL TI - Use of hamster antisera in the preliminary differentiation of Leptospira interrogans servars hardjo and balcanica. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial MH - Hamsters MH - Immune Sera MH - Leptospira interrogans/*classification/genetics/immunology MH - Serotyping MH - Variation (Genetics) PT - JOURNAL ARTICLE DA - 781027 DP - 1978 Aug IS - 0022-2615 TA - J Med Microbiol PG - 351-3 SB - M CY - ENGLAND IP - 3 VI - 11 JC - J2N AA - Author EM - 7812 AB - Preliminary differentiation of Leptospira interrogans serovars hardjo and balcanica can be made with antisera that are collected from hamsters after experimental infection with serovar hardjo and selected for high homologous and low or nil heterologous titres, as measured by the microscopic agglutination test. Rabbit antisera against serovars hardjo and balcanica, cattle antisera against hardjo and sheep antisera against the serogroup Hebdomadis each agglutinated hardjo and balcanica to a similar titre. PMID- 567250 CU - 85 SO - J Med Microbiol 1978 Aug;11(3):351-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 78251894 AU - Corrigall W TI - Naturally occurring leptospirosis (Leptospiraballum) in a red deer (Cervus elaphus). LA - Eng MH - Animal MH - *Deer MH - Leptospirosis/pathology/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 781018 DP - 1978 Jul 22 IS - 0042-4900 TA - Vet Rec PG - 75-6 SB - M CY - ENGLAND IP - 4 VI - 103 JC - XBS EM - 7812 PMID- 685108 SO - Vet Rec 1978 Jul 22;103(4):75-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 79013945 AU - Sefer M TI - [Antibiograms of Leptospira on solid media in Petri dishes] LA - Rum MH - Antibiotics/*pharmacology MH - English Abstract MH - Leptospira/*drug effects MH - Microbial Sensitivity Tests PT - JOURNAL ARTICLE DA - 781202 DP - 1978 Jul-Sep IS - 0376-4494 TA - Rev Ig [Bacteriol] PG - 177-81 SB - M CY - ROMANIA IP - 3 VI - 23 JC - S7C AA - Author EM - 7901 AB - The sensitivity of fowl leptospirae to antibiotics was tested by diffusiometry on solid media in Petri dishes. The method includes two stages: 1) visible leptospirae cultures are obtained by central seeding and incubation during 3--5 days at 28 or 37 degrees C; 2) antibiotic tablets are disposed at 2 cm from the visible edge of the multiplication zone of the leptospirae. The edge is marked with a pencil at the moment in which the antibiotics are applied. Incubation is continued at the same temperatures. The results are read after five days taking as reference the position of the marginal multiplication line. The sensitivity of leptospirae to antibiotics is expressed by arrested multiplication and resistance by advance of the marginal multiplication line up to or even beyond the antibiotic tablets. Fowl leptospirae are sensitive to penicillin, tetracyclin, chloramphenicol, streptomycin, novobiocin, polymixin, pristinamycin, neomycin, erythromycin, and resistant to mycostatin, septrin, rifampicin, optoquine, sulphatiazol. PMID- 694333 TT - Antibiograma leptospirelor pe medii solide in placi Petri. EA - A SO - Rev Ig [Bacteriol] 1978 Jul-Sep;23(3):177-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 79007668 AU - Hathaway SC AU - Blackmore DK AU - Marshall RB TI - The serologic and cultural prevalence of Leptospira interrogans serovar balcanica in possums (Trichosurus vulpecula) in New Zealand. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Female MH - Kidney/microbiology MH - Leptospira interrogans/*immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - Male MH - New Zealand MH - Opossums/*immunology PT - JOURNAL ARTICLE DA - 781202 DP - 1978 Jul IS - 0090-3558 TA - J Wildl Dis PG - 345-50 SB - M CY - UNITED STATES IP - 3 VI - 14 JC - KEM AA - Author EM - 7901 AB - In a serologic and cultural survey of 127 brush-tailed possums (Trichosurus vulpecula) occupying pasture land in New Zealand, leptospires of the Hebdomadis serogroup were obtained from 48 (38%) of the animals sampled. Eight isolates were identified by cross-absorption agglutin ation studies as being Leptospira interrogans serovar balcanica. There was a marked age difference in prevalence with 41 positive cultures from 64 mature adults (64%) and no recoveries being made from juveniles. Isolation of leptospires was aided by the use of a new technique involving the homogenation of whole kidneys in gamma sterilized plastic bags in a "Coleworth Stomacher". The use of this apparatus allowed the processing of whole kidneys and the technique was efficient in both the recovery of leptospires and the prevention of contamination. In view of the fact that serovar balcanica has been recorded previously only in East Europe in man, cattle and pigs, the high prevalence of infection in a wild animal population in New Zealand is an interesting development in the world distribution of this serovar. PMID- 691129 SO - J Wildl Dis 1978 Jul;14(3):345-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 78251941 AU - Kirpichev AF TI - [Cases of mixed infection in swine] LA - Rus MH - Abortion, Therapeutic/veterinary MH - Abortion, Veterinary/etiology MH - Animal MH - Female MH - Leptospirosis/veterinary MH - Pregnancy MH - Pseudorabies/diagnosis MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 781018 DP - 1978 Jul IS - 0042-4846 TA - Veterinariia PG - 53-4 CY - USSR IP - 7 JC - XCC EM - 7812 PMID- 685142 TT - Sluchai smeshannoi infektsii u svinei. SO - Veterinariia 1978 Jul;(7):53-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 78233516 AU - Bey RF AU - Johnson RC TI - Humoral immune responses of cattle vaccinated with leptospiral pentavalent outer envelope and whole culture vaccines. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - *Antibody Formation MH - *Bacterial Vaccines MH - Cattle/*immunology MH - Comparative Study MH - Female MH - IgG/analysis MH - IgM/analysis MH - Leptospira/growth & development/*immunology MH - Leptospira canicola/growth & development/immunology MH - Leptospira interrogans/growth & development/immunology MH - Support, U.S. Gov't, P.H.S. MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 780929 DP - 1978 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1109-14 SB - M CY - UNITED STATES IP - 7 VI - 39 JC - 40C AA - Author EM - 7811 AB - The humoral immune response of cattle vaccinated with leptospiral pentavalent outer envelope and whole culture vaccines was monitored with the microscopic agglutination (MA) test and the leptospiricidal activity (LA) test for a 2.5-year period. The serovars present in the vaccines were canicola, icterohaemorrhagiae, grippotyphosa, pomona, and hardjo. The LA test had greater sensitivity than the MA test for detecting antibodies to the hardjo, canicola, and icterohaemorrhagiae components of the pentavalent vaccine and was approximately equal in sensitivity to the MA test for detecting antibodies to the grippotyphosa and pomona components of the leptospiral vaccine. Both IgM and IgG were produced in similar amounts in the immunized cattle, and both classes were reactive in the MA and the LA tests. The IgM class of antibodies was more reactive in the MA test, whereas the IgG class of antibodies was more reactive in the LA test. Using the MA test as the criterion of evaluating, the immunogenic potency of the individual vaccine components was found to be canicola more than icterohaemorrhagiae more than grippotyphosa more than pomona more than hardjo. A direct correlation between protective antibodies, as determined by the hamster passive protection test, and antibodies reactive in the MA and the LA tests was observed. RO - M:MYA PMID- 677529 LR - 810811 SO - Am J Vet Res 1978 Jul;39(7):1109-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 79017563 AU - Busygin FF AU - Shaiman MS AU - Chulovskii IK TI - [Regional epidemiologic characteristics of combined foci of tick-borne encephalitis, endemic rickettsioses and leptospirosis in Western Siberia] LA - Rus MH - Animal MH - Arachnid Vectors MH - Cattle MH - Cattle Diseases/epidemiology MH - Encephalitis, Tick-Borne/*epidemiology/veterinary MH - English Abstract MH - Geography MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Q Fever/epidemiology/veterinary MH - Reindeer MH - Rickettsia Infections/*epidemiology/veterinary MH - Siberia MH - Ticks PT - JOURNAL ARTICLE DA - 781122 DP - 1978 Jul IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 48-51 SB - M CY - USSR IP - 7 JC - Y9O AA - Author EM - 7901 AB - The authors carried out complex study of combined foci of infections with natural foci in Western Siberia and their reflection in human pathology. The results of serological examination of 5917 persons and of 1743 of farm animals in respect to tick-borne encephalitis, Asian tick-borne rickettsiosis, Q-rickettsiosis, and leptospiroses are analysed. Affection of the population with all the four infections in all the landscape zones under study was shown; the intensity of this affection with different infections differed. Combined natural foci of the mentioned infections were found to be widespread; epidemiological significance of such combination was unequal in different ladscapes, this depending on the ladscape characteristics of the natural foci of infections under study and of different ways of transmission of their causative agents. PMID- 581250 CU - 88 TT - Landshaftno-epidemiologicheskaia kharakteristika sochetannykh ochagov kleshchevogo entsefalita, endemicheskikh rikketsiozov i leptospirozov v Zapadnoi Sibiri. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1978 Jul;(7):48-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 79017569 AU - Baryshev PM AU - Chernukha IuG AU - Shishkina ZS AU - Kokovin IL TI - [Formation of group and intergroup antibodies in humans with leptospirosis infections] LA - Rus MH - *Antibody Formation MH - Circadian Rhythm MH - English Abstract MH - Human MH - IgG/biosynthesis MH - IgM/biosynthesis MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology MH - Serotyping MH - Species Specificity MH - Time Factors PT - JOURNAL ARTICLE DA - 781122 DP - 1978 Jul IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 74-81 SB - M CY - USSR IP - 7 JC - Y9O AA - Author EM - 7901 AB - The authors studied regularities attending the biosynthesis of group (homologous) and intergroup (heterologous) antibodies in man during the whole cycle of leptospirosis infection, and for three months after it. Leptospira of the serological groups Pomona, Grippotyphosa, Icterohaemorrhagiae, Hebdomadis, the most prominent in the morbidity structure at present, served as etiological causative agents of the disease. Biosynthesis of both homologous and heterologous antibodies had its specific features for each serological group of the disease, and was characterized by the quadripol dynamics of 19S-macro and 7S- microglobulin antibodies production in leptospiroses of serological groups Pomona and Gryppotyphosa, whereas in leptospiroses of serological groups Icterohaemorrhagiae and Hebdomadis a graphically dipolic synthesis dynamics of 19S-macroglobulin antibodies alone was noted. PMID- 567919 CU - 90 TT - Obrazovanie gruppovykh i mezhgruppovykh antitel pri leptospiroznoi infektsii u cheloveka. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1978 Jul;(7):74-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 79001342 AU - Hussain B AU - Gbadamosi SG AU - Siddique IH TI - Serological studies on leptospirosis in cattle in east central Alabama. LA - Eng MH - Alabama MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*immunology MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 781129 DP - 1978 Jul IS - 0008-4050 TA - Can J Comp Med PG - 373-5 SB - M CY - CANADA IP - 3 VI - 42 JC - CI0 AA - Author EM - 7901 AB - Serological surveys of leptospiral antibodies in cattle were carried out in Macon and the surrounding counties of East Central Alabama. A total of 286 bovine serum samples were screened for the presence of antibodies against live antigens from twelve pathogenic leptospiral serotypes using a microscopic agglutination test. The most frequently encountered serotypes were Leptospira hardjo (47%), Leptospira wolffi (34%), Leptospira canicola (12%), Leptospira pomona (10%) and Leptospira ballum (10%). Leptospira autumnalis, Leptospira grippotyphosa, Leptospira icterohemorrhagiae, Leptospira pyrogenes and Leptospira tarassovi were observed in less than 5% of the samples. PMID- 567520 CU - 85 SO - Can J Comp Med 1978 Jul;42(3):373-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 80152699 AU - Nicolescu M TI - Recent studies on Leptospira and leptospirosis in the Cantacuzino Institute (1968--1977). LA - Eng MH - Age Factors MH - Animal MH - Bacteriological Techniques MH - Complement Fixation Tests MH - Diagnosis, Laboratory MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/complications/diagnosis/*epidemiology MH - Occupations MH - Romania MH - Seasons PT - JOURNAL ARTICLE DA - 800530 DP - 1978 Jul-Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 207-16 CY - ROMANIA IP - 3-4 VI - 37 JC - 8EM EM - 8007 PMID- 395925 CU - 90 SO - Arch Roum Pathol Exp Microbiol 1978 Jul-Dec;37(3-4):207-16 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 79091127 AU - Coetzer JA AU - Schutte AP TI - [Infectious causes of perinatal mortalities in ruminants (author's transl)] LA - Afr MH - Abortion, Veterinary/*etiology MH - Animal MH - Aspergillus fumigatus MH - Babesiosis/pathology MH - Bluetongue MH - Bovine Virus Diarrhea-Mucosal Disease MH - Brucellosis MH - Campylobacter fetus MH - Campylobacter Infections/veterinary MH - Cattle MH - Cattle Diseases/*mortality MH - Chlamydia Infections/veterinary MH - Communicable Diseases/*veterinary MH - English Abstract MH - Female MH - Fetus/immunology MH - Immunoglobulins/analysis MH - Infectious Bovine Rhinotracheitis/pathology MH - Leptospirosis/veterinary MH - Listeria Infections/veterinary MH - Parainfluenza Virus 3, Human MH - Paramyxoviridae Infections/veterinary MH - Pregnancy MH - Q Fever/veterinary MH - Rift Valley Fever/pathology MH - Salmonella Infections, Animal MH - Sheep MH - Sheep Diseases/*mortality MH - Toxoplasmosis, Animal MH - Trichomonas Infections/veterinary MH - Virus Diseases/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 790324 DP - 1978 Jul IS - 0301-0732 TA - J S Afr Vet Assoc PG - 89-98 SB - M CY - SOUTH AFRICA IP - 2 VI - 49 JC - JZH AA - Author EM - 7905 AB - The advantages and disadvantages of the different diagnostic techniques e.g. pathological and microbiological studies, immunoglobulin and specific antibody determinations and fluorescent antibody studies in relation to these mortalities are discussed. The most important pathological lesions in the placentas and foetuses are described. RF - 86 PMID- 215769 CU - 96 TT - Besmetlike oorsake van perinatale vrektes by herkouers. EA - A SO - J S Afr Vet Assoc 1978 Jul;49(2):89-98 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 79031389 AU - Petricivic I AU - Benic V AU - Lehpamer B TI - [Transient (benign) monoclonal gammapathies in the course of infectious diseases (author's transl)] LA - Scr MH - Aged MH - Case Report MH - Child, Preschool MH - Cytomegalovirus Infections/complications MH - English Abstract MH - Hepatitis, Viral, Human/complications MH - Human MH - Hypergammaglobulinemia/*complications MH - *IgG MH - *IgM MH - Leptospirosis/complications MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 781229 DP - 1978 Jul IS - 0024-3477 TA - Lijec Vjesn PG - 433-6 CY - YUGOSLAVIA IP - 7 VI - 100 JC - L6C EM - 7902 PMID- 212656 CU - 93 TT - Prolazne (benigne) monoklonalne gamapatije u toku infekcioznih bolesti. EA - A SO - Lijec Vjesn 1978 Jul;100(7):433-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 79034768 AU - Hellstrom JS AU - Marshall RB TI - Survival of Leptospira interrogans serovar pomona in an acidic soil under simulated New Zealand field conditions. LA - Eng MH - Animal MH - Culture Media MH - Hamsters MH - Hydrogen-Ion Concentration MH - Leptospira interrogans/growth & development/*isolation & purification MH - New Zealand MH - *Soil Microbiology PT - JOURNAL ARTICLE DA - 781220 DP - 1978 Jul IS - 0034-5288 TA - Res Vet Sci PG - 29-33 SB - M CY - ENGLAND IP - 1 VI - 25 JC - R7D AA - Author EM - 7902 AB - Leptospira interrogans serovar pomona was found to survive for at least 42 days in a typical New Zealand soil under simulated winter field conditions. The soil was markedly acidic with a pH of 5.5 and survival times were not reduced even when its water content was only 23%. The values of both these parameters are considerably less than previously recorded for the survival of leptospires in soil. Two methods were used to recover leptospires from the soil microflora. One was the culture of a membrane filtrate in EMJH media with or without contaminant- suppressing additives and the other was the direct inoculation of soil- washings into hamsters. Both techniques proved to equally sensitive. It was estimated that following the addition of 5 X 10(8) leptospires to the soil samples less than 2 X 10(4) were present after six weeks. PMID- 30123 CU - 94 SO - Res Vet Sci 1978 Jul;25(1):29-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 79077970 AU - Wolff JW TI - The possible pathogenicity of water leptospires (L. biflexa) 1920-1930. LA - Eng MH - Animal MH - English Abstract MH - Guinea Pigs MH - History of Medicine, 20th Cent. MH - Human MH - Leptospira/classification/*pathogenicity MH - Microbiology/*history MH - Netherlands MH - Rats MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 790212 DP - 1978 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 175-82 SB - M CY - NETHERLANDS IP - 2 VI - 30 JC - WGJ EM - 7904 RO - M:JJK RO - M:MYA PMID- 726030 LR - 820806 EA - A SO - Trop Geogr Med 1978 Jun;30(2):175-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 79031354 AU - Beus A AU - Hirtzler R AU - Beus I TI - [A fatal case of leptospiral myocarditis (author's transl)] LA - Scr MH - Adult MH - Case Report MH - English Abstract MH - Human MH - *Leptospirosis/pathology MH - Male MH - Myocarditis/*etiology/pathology MH - Myocardium/pathology PT - JOURNAL ARTICLE DA - 781220 DP - 1978 Jun IS - 0024-3477 TA - Lijec Vjesn PG - 349-52 CY - YUGOSLAVIA IP - 6 VI - 100 JC - L6C EM - 7902 PMID- 703488 TT - Leptospirozni miokarditis sa smrtnim ishodom. EA - A SO - Lijec Vjesn 1978 Jun;100(6):349-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 79016536 AU - Green AE AU - Sulzer CR AU - Evarard CO AU - Jones WL TI - Four new leptospira serotypes from Trinidad. LA - Eng MH - Adolescence MH - Agglutination Tests MH - Animal MH - Case Report MH - Human MH - Leptospira/classification/*isolation & purification MH - Male MH - Mongoose MH - Rats MH - Serotyping MH - Trinidad and Tobago PT - JOURNAL ARTICLE DA - 781118 DP - 1978 Jun IS - 0043-3144 TA - West Indian Med J PG - 117-26 CY - JAMAICA IP - 2 VI - 27 JC - XN4 EM - 7901 PMID- 695552 CU - 90 SO - West Indian Med J 1978 Jun;27(2):117-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 79011627 AU - Chabudzinska S AU - Kacprzak-Bergman I TI - [Diagnostic difficulties in multiorgan form of Mycoplasma infection] LA - Pol MH - Brain Abscess/diagnosis MH - Case Report MH - Child, Preschool MH - Diagnosis, Differential MH - Female MH - Human MH - Leptospirosis/diagnosis MH - Male MH - Mycoplasma Infections/*diagnosis PT - JOURNAL ARTICLE DA - 781129 DP - 1978 Jun IS - 0031-3939 TA - Pediatr Pol PG - 769-71 CY - POLAND IP - 6 VI - 53 JC - OW2 EM - 7901 PMID- 693133 TT - Trudnosci diagnostyczne w wielonarzadowej postaci mykoplazmozy. SO - Pediatr Pol 1978 Jun;53(6):769-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 78256598 AU - Elder JK AU - Ward WH TI - The prevalence and distribution of leptospiral titres in cattle and pigs in Queensland. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Australia MH - Cattle/*immunology MH - Cattle Diseases/epidemiology MH - Female MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/veterinary MH - Rain MH - Swine/*immunology MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 781027 DP - 1978 Jun IS - 0005-0423 TA - Aust Vet J PG - 297-300 SB - M CY - AUSTRALIA IP - 6 VI - 54 JC - 9IE AA - Author EM - 7812 AB - Serological test results for leptospiral species on serums from cattle and pigs performed by the diagnostic laboratories of the Queensland Department of Primary Industries from July 1973 to June 1976 were used to determine the prevalence and geographical distribution of 3 leptospiral serotypes in Queensland. There was a higher prevalence of antibodies to L. hardjo than to L. pomona in cattle, whereas in pigs the prevalence of antibodies to L. pomona was much higher than that for L. tarassovi or L. hardjo. Feral pigs had a particularly high prevalence of L. pomona antibodies. There is a different geographical distribution of antibodies to L. pomona and L. hardjo. L. hardjo antibodies appear to be fairly uniformly distributed but there is a higher prevalence of L. pomona antibodies in low rainfall areas. This relationship was shown to be significantly correlated. PMID- 687297 CU - 90 SO - Aust Vet J 1978 Jun;54(6):297-300 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 78220128 AU - Bell MJ AU - Ternberg JL AU - Feigin RD TI - Surgical complications of leptospirosis in children. LA - Eng MH - Acute Disease MH - Biliary Tract Diseases/*etiology/surgery MH - Case Report MH - Child MH - Child, Preschool MH - Cholecystitis/etiology/surgery MH - Female MH - Gangrene/*etiology/surgery MH - Human MH - Leptospirosis/*complications/diagnosis MH - Male MH - Pancreatitis/*etiology PT - JOURNAL ARTICLE DA - 780929 DP - 1978 Jun IS - 0022-3468 TA - J Pediatr Surg PG - 325-30 SB - M CY - UNITED STATES IP - 3 VI - 13 JC - JMJ EM - 7811 PMID- 671199 SO - J Pediatr Surg 1978 Jun;13(3):325-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 78208372 AU - Anderson DC AU - Folland DS AU - Fox MD AU - Patton CM AU - Kaufmann AF TI - Leptospirosis: a common-source outbreak due to leptospires of the grippotyphosa serogroup. LA - Eng MH - Adolescence MH - Child MH - Disease Outbreaks/*epidemiology MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology/microbiology MH - Male MH - Swimming MH - Tennessee MH - Water Pollutants/isolation & purification MH - Water Pollution PT - JOURNAL ARTICLE DA - 780828 DP - 1978 Jun IS - 0002-9262 TA - Am J Epidemiol PG - 538-44 SB - M CY - UNITED STATES IP - 6 VI - 107 JC - 3H3 AA - Author EM - 7810 AB - In the period August 1-10, 1975, seven cases of leptospirosis occurred in residents of Stewart County, Tennessee. Based on serologic evidence, the infection was caused by leptospires of the Grippotyphosa serogroup. Epidemiologic study showed that the patients apparently acquired their infection while swimming in Cub Creek, a small local stream. Stagnation of the stream resulting from subnormal rainfall may have contributed to the timing of the outbreak. The source of leptospiral contamination for the stream could not be determined. PMID- 665667 CU - 88 SO - Am J Epidemiol 1978 Jun;107(6):538-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 79047472 AU - Schnurrenberger PR AU - Hanson LE AU - Martin RJ TI - Infections with Erysipelothrix, Leptospira, and Chlamydia in Illinois veterinarians. LA - Eng MH - Animal MH - Brucellosis/epidemiology MH - Comparative Study MH - Erysipelothrix Infections/*epidemiology MH - Female MH - Human MH - Illinois MH - Leptospirosis/*epidemiology MH - Male MH - Occupational Diseases/*epidemiology MH - Ornithosis/*epidemiology MH - *Veterinary Medicine PT - JOURNAL ARTICLE DA - 790115 DP - 1978 Jun IS - 0377-0168 TA - Int J Zoonoses PG - 55-61 SB - M CY - TAIWAN IP - 1 VI - 5 JC - GTK EM - 7903 PMID- 568604 CU - 88 SO - Int J Zoonoses 1978 Jun;5(1):55-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 79023164 AU - Bazovska S TI - [Sphingomyelinase activity of Leptospira cultures (author's transl)] LA - Slo MH - English Abstract MH - Hemolysis MH - Leptospira/*enzymology MH - Phospholipases/metabolism MH - Phosphoric Diester Hydrolases/*metabolism MH - Sphingomyelin Phosphodiesterase/*metabolism PT - JOURNAL ARTICLE DA - 781227 DP - 1978 Jun IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 137-43 CY - CZECHOSLOVAKIA IP - 3 VI - 27 JC - CSH EM - 7902 PMID- 212210 CU - 93 TT - Sfingomyelinazova aktivita leptospirovych kultur. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1978 Jun;27(3):137-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 78177306 AU - Terpstra WJ TI - [Van Weil's disease and other leptospiroses] LA - Dut MH - Human MH - Leptospirosis/*epidemiology MH - Netherlands MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 780724 DP - 1978 May 27 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 776 CY - NETHERLANDS IP - 21 VI - 122 JC - NUK EM - 7809 PMID- 652094 CU - 88 TT - Ziekte van Weil en andere leptospirosen. SO - Ned Tijdschr Geneeskd 1978 May 27;122(21):776 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 79080955 AU - Bey RF AU - Johnson RC TI - Humoral immune response of dogs vaccinated with leptospiral pentavalent outer envelope and whole culture vaccines. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antibody Formation MH - *Bacterial Vaccines MH - Dogs/*immunology MH - IgG/analysis MH - IgM/analysis MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Support, U.S. Gov't, P.H.S. MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 790221 DP - 1978 May IS - 0002-9645 TA - Am J Vet Res PG - 831-6 SB - M CY - UNITED STATES IP - 5 VI - 39 JC - 40C AA - Author EM - 7904 AB - The humoral immune response of dogs vaccinated with leptospiral pentavalent outer envelope and whole culture vaccines was monitored with the microscopic agglutination (MA) test and leptospiricidal activity (LA) test for a 2-year period. The leptospiral serovars in the vaccines was canicola, icterohaemorrhagiae, grippotyphosa, pomona, and hardjo. The LA test was markedly more sensitive than the MA test for detecting anti-Leptospira antibodies and was least noticeable with anti- pomona antibodies. Both Igm and IgG were produced in similar amounts in the vaccinated dogs, and both classes of immunoglobulins were reactive in the MA and LA tests. The IgM class of antibodies was slightly more reactive in the MA test, whereas IgG antibodies were somewhat more reactive in the LA test. A direct correlation between protective antibodies, as determined by the hamster passive-protection test, and antibodies reactive in the MA and LA tests was observed. PMID- 727583 SO - Am J Vet Res 1978 May;39(5):831-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 78249894 AU - Caldas EM AU - Costa E AU - Sampaio MB TI - [Leptospirosis in Salvador (Brazil). Clinical and laboratory aspects] LA - Por MH - Brazil MH - Diagnosis, Differential MH - English Abstract MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*diagnosis/epidemiology MH - Weil's Disease/*diagnosis/epidemiology PT - JOURNAL ARTICLE DA - 781018 DP - 1978 May-Jun IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 164-76 CY - BRAZIL IP - 3 VI - 20 JC - S9D EM - 7812 PMID- 684326 CU - 88 TT - Leptospirose na cidade do Salvador (Brasil). Alguns aspectos clinicos e laboratoriais. EA - A SO - Rev Inst Med Trop Sao Paulo 1978 May-Jun;20(3):164-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 78205195 AU - Morales GA AU - Guzman VH AU - Beltran LE TI - Leptospirosis in Colombia: isolation of Leptospira spp. from the kidneys of brown rats (Rattus norvegicus) trapped on infected piggeries. LA - Eng MH - Animal MH - Colombia MH - Kidney/*microbiology MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/transmission/*veterinary MH - Rats/*microbiology MH - Swine MH - Swine Diseases/*transmission PT - JOURNAL ARTICLE DA - 780901 DP - 1978 May IS - 0049-4747 TA - Trop Anim Health Prod PG - 121-3 SB - M CY - SCOTLAND IP - 2 VI - 10 JC - WG2 AA - Author EM - 7810 AB - Leptospira interrogans serotypes pomona and icterohaemorrhagiae were isolated from the kidneys of Rattus norvegicus trapped on pomona infected piggeries. The isolation of pomona from one of 111 cultured kidneys, although of interest, strongly suggests that this rat does not play an important part in the epidemiology of infection by this serotype. Kidney tubular degeneration, focal mononuclear infiltrations and fibroplasia are morphological traces which remain after an attack of leptospirosis. The high percentage (48.6) of these lesions found in the rat kidneys examined does not seem to be related to serotype pomona but to icterohaemorrhagiae. The importance of this last serotype in swine in the Cauca Valley has yet to be assessed. PMID- 664013 SO - Trop Anim Health Prod 1978 May;10(2):121-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 78228768 AU - Chernukha IuG AU - Baryshev PM TI - [Leptospirosis (epidemiology, immunity, immunodiagnosis and control and preventive measures)] LA - Rus MH - Agglutination Tests MH - Antibodies, Bacterial/isolation & purification MH - Human MH - *Leptospirosis/diagnosis/microbiology/prevention & control MH - Rural Health MH - USSR PT - JOURNAL ARTICLE PT - REVIEW DA - 780929 DP - 1978 May IS - 0038-5077 TA - Sov Med PG - 83-8 CY - USSR IP - 5 JC - UW7 EM - 7811 RF - 97 PMID- 354020 CU - 90 TT - Leptospiroz (epidemiologiia, immunitet, immunodiagnostika, mery bor'by i profilaktiki). SO - Sov Med 1978 May;(5):83-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 78207256 AU - Abushev FA TI - [Study data on ornithosis infection in the Azerbaijan SSR] LA - Rus MH - Animal MH - Azerbaijan MH - Bird Diseases/immunology MH - Birds/immunology MH - Disease Reservoirs MH - Disease Vectors MH - English Abstract MH - Human MH - Ornithosis/*epidemiology/immunology MH - Poultry/immunology MH - Poultry Diseases/immunology PT - JOURNAL ARTICLE DA - 780814 DP - 1978 May IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 83-6 SB - M CY - USSR IP - 5 JC - Y9O AA - Author EM - 7810 AB - Data are presented on the study of epizootology and epidemiology of ornithosis. There were revealed natural foci of ornithosis in the Kyzyl- Agach preserve, at the Sary-Su lakes and at the Glinyany island; these foci were dihostal and polyhostal, as well as conjointed (ornithosis, arboviruses, Q-fever, Asian tick-borne typhus, leptospirosis). Anthropurgic foci were found in 12 populated localities, semi-wild dove serving as the main component. Fowl was found to be infected in 12 poultry-farms; occupational ornithosis was present among the bird- rearers. Immunological structure of the population in respect to ornithosis was studied. Patients with various diagnoses showed positive serological reactions retrospectively; there were 155 cases of ornithosis among them. PMID- 149489 CU - 92 TT - Materialy izucheniia ornitoznoi infektsii v Azerbaidzhanskoi SSR. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1978 May;(5):83-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78207230 AU - Baryshev PM AU - Shishkina ZS AU - Chernukha IuG AU - Kokovin IL AU - Malkina LA TI - [Comparative study of the immunoglobulin content in persons from leptospirosis foci in different geographical zones of the RSFSR] LA - Rus MH - Adolescence MH - Adult MH - Child MH - Child, Preschool MH - Comparative Study MH - *Disease Reservoirs MH - English Abstract MH - Human MH - IgA/*analysis MH - IgG/*analysis MH - IgM/*analysis MH - Infant MH - Infant, Newborn MH - Leptospirosis/*immunology MH - Middle Age MH - Russia MH - Weil's Disease/*immunology PT - JOURNAL ARTICLE DA - 780814 DP - 1978 May IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 122-7 SB - M CY - USSR IP - 5 JC - Y9O AA - Author EM - 7810 AB - The authors carried out a comparative study of the content of serum immunoglobulins in persons from the leptospirosis foci of various geographical zones of the RSFSR: European part--the Centre (Moscow and Ryazan regions), the South (Checheno-Ingush ASSR and Krasnodar Territory), and Western Siberia (Altai territory), Leptospira of serological group Pomona, Grippotyphosa, and Hbedomadis served as the causative agents of the diseases. It appeared that the annual course of the climatic factors acted equally (inhibitory action) on the immuno- globulin metabolism in the residents of temperate and southern zones of the RSFSR at the warm period of the year (May-September), and in the Western Siberia- in winter. However, irrespective of the time of the year, the level of immunoglobulins G and A was greater in the residents of Western Siberia than in the native population of the European part. There proved to be no correlation between the levels of leptospirosis seropositivity in the foci of infection under study and the serum immunoglobulins in local residents of various geographical zones. PMID- 149486 CU - 92 TT - Sranvitel'noe izuchenie soderzhaniia immunoglobulinov u liudei iz ochagov leptospiroza razlichnykh geograficheskikh zon RSFSR. EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1978 May;(5):122-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 78227441 AU - Vilaseca J AU - Ruiz J AU - Ballester M AU - Villalonga C AU - Pedreira JD AU - Richart C AU - Bacardi R TI - [Clinical considerations on Weil's disease] LA - Spa MH - Adult MH - Case Report MH - Diagnosis, Differential MH - English Abstract MH - Human MH - Leptospira/*isolation & purification MH - Male MH - Middle Age MH - Weil's Disease/*microbiology PT - JOURNAL ARTICLE DA - 780925 DP - 1978 Apr 15 IS - 0014-2565 TA - Rev Clin Esp PG - 63-6 CY - SPAIN IP - 1 VI - 149 JC - RNL EM - 7811 PMID- 674755 TT - Consideraciones clinicas sobre la enfermedad de Weil. EA - A SO - Rev Clin Esp 1978 Apr 15;149(1):63-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 78209245 AU - Kayser A AU - Adrian M TI - [Spirochetes: coiling direction] LA - Fre MH - English Abstract MH - *Leptospira MH - Microscopy, Electron MH - *Treponema PT - JOURNAL ARTICLE DA - 780828 DP - 1978 Apr IS - 0300-5410 TA - Ann Microbiol (Paris) PG - 351-60 SB - M CY - FRANCE IP - 3 VI - 129 JC - 5JY AA - Author EM - 7810 AB - On electron micrographs of spirochetes, the axial fibers are alternatively visible and hidden, i.e. above then under the cytoplasmic cylinder. From this observation the sense of coiling can be inferred. Leptospires are right-handed structures. So are other spirochetes, but it is less conspicuous. The opposite, however, appears on most published photographs and on schematic drawings. The explanation would be that the preparation introduced into the electron microscope was not facing the photographic plate, but turned to the electron beam. Also the picture must not be turned over, neither in the photographic laboratory nor when used as a slide. PMID- 666219 TT - Les spirochetes: sens de l'enroulement. EA - A SO - Ann Microbiol (Paris) 1978 Apr;129(3):351-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 78209240 AU - Bisso GM AU - Silva I AU - Merli F TI - Gas-liquid-chromatography of trimethylsilyl derivatives from whole cell methanolysates of Leptospira : preliminary evaluation of its applicability to the taxonomy of the genus. LA - Eng MH - *Chromatography, Gas MH - English Abstract MH - Leptospira/analysis/*classification MH - Trimethylsilyl Compounds/analysis PT - JOURNAL ARTICLE DA - 780828 DP - 1978 Apr IS - 0300-5410 TA - Ann Microbiol (Paris) PG - 295-311 SB - M CY - FRANCE IP - 3 VI - 129 JC - 5JY AA - Author EM - 7810 AB - Gas-liquid-chromatography of trimethylsilyl derivatives from whole cell methanolysates was investigated as a supplmentary means for taxonomical classification within the genus Leptospira. Reproducibility of this technique was assessed through the peak height variations occurring in chromatograms of strain Patoc 1, serotype patoc, when samples either from the same or different batches of culture were used. From each chromatogram seven peaks were selected. Their heights were measured and calculated as percent values of the seven peaks total height. The values of relative standard deviation reported show that the reproducibility of this technique lies within the usual limits of biological methods. Four out of seven different serotypes analyzed gave elution patterns dissimilar enough to allow a clear distinction among them by the simple visual examination. Differentiation of the other three had to be done comparing the relative heights of the seven selected peaks. One not yet classified new strain was submitted to this technique; results seemed to confirm available serological information about it. Data reported encourage further research in order to evaluate the potential of GLC as an useful aid in the taxonomy of genus Leptospira. RO - M:JJK RO - M:MYA PMID- 666215 LR - 820805 CU - 90 EA - A SO - Ann Microbiol (Paris) 1978 Apr;129(3):295-311 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 78207109 AU - Yanagawa R AU - Adachi Y TI - Studies of antigenic variants of leptospira isolated from experimentally infected mice. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Kidney/immunology MH - Leptospira/classification/*immunology/isolation & purification MH - Mice PT - JOURNAL ARTICLE DA - 780901 DP - 1978 Apr IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 437-55 SB - M CY - GERMANY, WEST IP - 3 VI - 240 JC - Y52 AA - Author EM - 7810 AB - Antigenic variants were isolated from mice inoculated with a virulent strain of Leptospira interrogans serotype copenhageni by cultivating the kidney cortex in the liquid or the solidified serum media containing the immune serum against the parent strain. The variants, which were isolated from the mice from 7 to 113 days after infection, were found to be antigenically different from the parent by the agglutinin-absorption test, precipitin-absorption test in gel and guinea pig protection test. The variants were antigenically stable and different from the 18 serotypes of the Icterohaemorrhagiae serogroup. The significance of antigenic variants of leptospira which appear in vivo is discussed. PMID- 664984 SO - Zentralbl Bakteriol [Orig A] 1978 Apr;240(3):437-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 78207100 AU - Cinco M AU - Ivanov I TI - Characterization of a new strain of leptospira isolated from surface water in India. LA - Eng MH - Clone Cells MH - India MH - Leptospira/classification/immunology/*isolation & purification MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 780901 DP - 1978 Apr IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 356-8 SB - M CY - GERMANY, WEST IP - 3 VI - 240 JC - Y52 AA - Author EM - 7810 AB - A new strain of Leptospira, isolated from surface water in India, is studied and classified. It shows, in the biological tests, a behaviour like that of saprophytic leptospirae; further serovar it represents a new serovar which we named poona. PMID- 664981 SO - Zentralbl Bakteriol [Orig A] 1978 Apr;240(3):356-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 78174130 AU - Cirone SM AU - Riemann HP AU - Ruppanner R AU - Behymer DE AU - Franti CE TI - Evaluation of the hemagglutination test for epidemiologic studies of leptospiral antibodies in wild mammals. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals/*immunology MH - Animals, Wild/*immunology MH - Antibodies, Bacterial/*analysis MH - Carnivora/immunology MH - Comparative Study MH - Deer/immunology MH - *Hemagglutination Tests MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Rodentia/immunology PT - JOURNAL ARTICLE DA - 780724 DP - 1978 Apr IS - 0090-3558 TA - J Wildl Dis PG - 193-202 SB - M CY - UNITED STATES IP - 2 VI - 14 JC - KEM AA - Author EM - 7809 AB - Sera from 153 wild animals of 18 species were tested for antibodies against 12 serovars of Leptospira by the microscopic agglutination (MA) test. Seventy-five percent of the animals tested were seropositive against one or more of the 12 serovars used. The most commonly found serovars were pomona, autumnalis, pyrogenes, icterohaemorrhagiae, australis, and canicola. Of 62 carnivores representing 7 species, 55 (89%) were seropositive, as were 46 (60%) of 77 rodents from 9 species. Leptospira of the serovar copenhageni serogroup icterohaemorrhagiae were recovered from kidney tissues of a Norway rat (Rattus norvegicus). Of 443 wildlife sera tested by the indirect hemagglutination (IHA) test using cells sensitized with L. illini antigen, 47 (11%), mainly carnivores and deer, gave a heterophile reaction. Of the remaining 396 sera, 164 (41%) were seropositive for leptospirosis by the IHA test. To compare the IHA test with the MA test, 143 serum samples were tested by both methods. There was 84% concordance between the two tests. PMID- 650784 CU - 90 SO - J Wildl Dis 1978 Apr;14(2):193-202 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 78165603 AU - Sasse D AU - Reuter G TI - [Survival ability of Leptospira pomona in kidney and muscle tissue of slaughtered pigs in freezing temperatures] LA - Ger MH - Animal MH - English Abstract MH - *Food Microbiology MH - *Food Preservation MH - *Frozen Foods MH - Kidney/microbiology MH - *Leptospira MH - *Meat MH - Muscles/microbiology MH - *Swine MH - Temperature PT - JOURNAL ARTICLE DA - 780617 DP - 1978 Apr 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 130-6 CY - GERMANY, WEST IP - 7 VI - 91 JC - 9Q8 EM - 7808 PMID- 646773 CU - 90 TT - Prufung der Uberlebensfahigkeit von Leptospira pomona in Nieren- und Muskelgewebe von Schlachtschweinen bei Gefriertemperaturen. EA - A SO - Berl Munch Tierarztl Wochenschr 1978 Apr 1;91(7):130-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 78191376 AU - Budak AP TI - [Epidemiology and prevention of leptospirosis] LA - Rus MH - Human MH - Leptospirosis/*epidemiology/prevention & control MH - USSR PT - JOURNAL ARTICLE DA - 780828 DP - 1978 Apr IS - 0014-9772 TA - Feldsher Akush PG - 7-10 SB - N CY - USSR IP - 4 VI - 43 JC - EVA EM - 7810 PMID- 248038 CU - 88 LI - N TT - Epidemiologiia i profilaktika leptospirozov. SO - Feldsher Akush 1978 Apr;43(4):7-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78205495 AU - Kadlec V TI - [Observation on the antigenic affinity of Leptospira and Brucella in the serological examination of cattle] LA - Cze MH - *Agglutination Tests MH - Animal MH - Brucella abortus/*immunology MH - Cattle MH - *Cross Reactions MH - English Abstract MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 780828 DP - 1978 Apr IS - 0375-8427 TA - Vet Med (Praha) PG - 213-8 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 23 JC - XBP AA - Author EM - 7810 AB - 36,9% bovine serums which showed a non-specific reaction in examination for brucellosis had titre greater than or equal to 1:400 leptospirosis agglutinins. 15.1% of the serums showed a positive reaction (greater than 1:800), mostly those against L. sejroe and L. grippotyphosa. The cross reactions, found in individual cases within up to 39 days since the first reaction to brucellosis in cattle may signalize early Leptospira infections. PMID- 96568 CU - 91 TT - Pozorovani antigenni pribuznosti leptospir a brucel pri serologickem vysetrovani skotu. EA - A SO - Vet Med (Praha) 1978 Apr;23(4):213-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78134649 AU - Bergeson PS AU - Serlin SP AU - Corman LI TI - Mucocutaneous lymph-node syndrome with positive Weil-Felix reaction but negative Leptospira studies [letter] LA - Eng MH - Agglutination Tests/methods MH - Antigens, Bacterial/isolation & purification MH - Diagnosis, Differential MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis MH - Lymphatic Diseases/*diagnosis MH - Mucocutaneous Lymph Node Syndrome/*diagnosis MH - Proteus/immunology PT - LETTER DA - 780517 DP - 1978 Apr 1 IS - 0140-6736 TA - Lancet PG - 720-1 SB - A SB - M CY - ENGLAND IP - 8066 VI - 1 JC - L0S EM - 7807 PMID- 76261 CU - 95 SO - Lancet 1978 Apr 1;1(8066):720-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 78160948 AU - Johnston WG AU - Orr JP AU - Wright CL TI - Leptospirosis in cattle in south west Scotland [letter] LA - Eng MH - Animal MH - Cattle MH - *Cattle Diseases MH - Human MH - Leptospirosis/*veterinary MH - Scotland PT - LETTER DA - 780628 DP - 1978 Mar 25 IS - 0042-4900 TA - Vet Rec PG - 267 SB - M CY - ENGLAND IP - 12 VI - 102 JC - XBS EM - 7808 PMID- 644829 CU - 91 SO - Vet Rec 1978 Mar 25;102(12):267 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 78143390 AU - Henry RA AU - Johnson RC TI - Distribution of the genus Leptospira in soil and water. LA - Eng MH - Amphibia/microbiology MH - Animal MH - Fishes/microbiology MH - Fresh Water MH - Hamsters MH - Leptospira/*isolation & purification MH - Mesocricetus MH - Seasons MH - *Soil Microbiology MH - Support, U.S. Gov't, P.H.S. MH - Turtles/microbiology MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 780524 DP - 1978 Mar IS - 0099-2240 TA - Appl Environ Microbiol PG - 492-9 SB - M CY - UNITED STATES IP - 3 VI - 35 JC - 6K6 AA - Author EM - 7807 AB - The distribution of the aerobic spirochetes Leptospira in surface waters, soil, and aquatic animals was investigated. Isolates from water and soil exhibited physiological characteristics common to members of the "biflexa complex," none were capable of infecting experimental animals, and leptospires could not be isolated from the eight genera of aquatic animals examined. The isolation frequencies from surface waters were: stream, 100%; lake, 65%; spring, 28%; bog lake, 5%; and marsh, 0%. With the exception of the stream, more isolations were obtained from the soil adjacent to the water than from the water. Leptospires were most frequently associated with soils of high moisture and organic matter content. PMID- 637546 CU - 90 SO - Appl Environ Microbiol 1978 Mar;35(3):492-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 78142881 AU - Nervig RM AU - Cheville NF AU - Baetz AL TI - Experimental infection of calves with Leptospira interrogans serotype szwajizak. LA - Eng MH - Animal MH - Cattle MH - *Cattle Diseases/blood/microbiology MH - Female MH - Kidney/microbiology MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/blood/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 780524 DP - 1978 Mar IS - 0002-9645 TA - Am J Vet Res PG - 523-5 SB - M CY - UNITED STATES IP - 3 VI - 39 JC - 40C AA - Author EM - 7807 AB - This is a report on the experimental infection of cattle with Leptospira interrogans serotype szwajizak. The principal clinical features in three 4-week-old Holstein-Friesian heifers intravenously inoculated were fever, listlessness, anorexia, weakness, and diarrhea. Szwajizak was isolated from the blood for the first 5 to 8 days after inoculation. Leptospires were recovered from kidneys, but not from liver, spleen, brain, or urine. Two of the 3 calves produced homologous agglutinins, with maximum serum titers of 1:80 and 1:160. The sera of the 2 calves that developed szwajizak agglutinins showed cross reactivity with wolffi and hardjo antigens. There were not significant differences of plasma and urine constituents between the inoculated calves and the control calf. Endocardial hemorrhages and large soft black-red spleen were present in the 2 calves given the greatest numbers of leptospires. Histopathologically, kidney of all infected calves had multiple small foci of lymphoid cells, chiefly pasmacytes, which were present in periglomerular and interstitial areas. PMID- 637400 SO - Am J Vet Res 1978 Mar;39(3):523-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 78142865 AU - Keenan KP AU - Alexander AD AU - Mongomery CA Jr TI - Pathogenesis of experimental Leptospira interrogans, serovar bataviae, infection in the dog: microbiological, clinical, hematologic, and biochemical studies. LA - Eng MH - Animal MH - *Dog Diseases/blood/microbiology MH - Dogs MH - Female MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/blood/microbiology/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 780524 DP - 1978 Mar IS - 0002-9645 TA - Am J Vet Res PG - 449-54 SB - M CY - UNITED STATES IP - 3 VI - 39 JC - 40C EM - 7807 PMID- 637394 SO - Am J Vet Res 1978 Mar;39(3):449-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 79035563 AU - Watten RH AU - van Peenen PF AU - Joseph SW AU - Louhenapessy A AU - Cross JH TI - Biomedical survey in the Moluccas, Indonesia. LA - Eng MH - Adolescence MH - Adult MH - Antibodies/*analysis MH - Blood/*parasitology MH - Child MH - Encephalitis Virus, Japanese/immunology MH - Entamoeba histolytica/immunology MH - Female MH - Human MH - Indonesia MH - Intestines/*parasitology MH - Leptospira/immunology MH - Male MH - Orthomyxoviridae/immunology MH - Pseudomonas/immunology MH - Support, U.S. Gov't, Non-P.H.S. MH - Toxoplasma/immunology PT - JOURNAL ARTICLE DA - 781220 DP - 1978 Mar IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 20-4 SB - M CY - THAILAND IP - 1 VI - 9 JC - UVN EM - 7902 PMID- 212835 CU - 93 SO - Southeast Asian J Trop Med Public Health 1978 Mar;9(1):20-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 78207197 AU - Tagi-Zade TA AU - Agaev IA AU - Alekperov FP AU - Ibragimov AI AU - Mikaelian BA TI - [Outbreak of leptospirosis among the inhabitants of the village of Avaran in the Kusarsk region of the Azerbaijan SSR] LA - Rus MH - Animal MH - Azerbaijan MH - Disease Outbreaks MH - Human MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 780828 DP - 1978 Mar IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 142-3 SB - M CY - USSR IP - 3 JC - Y9O EM - 7810 PMID- 149483 CU - 92 TT - Vspyshka leptospiroza sredi liudei seleniia Avaran Kusarskogo raiona Azergaidzhanskoi SSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1978 Mar;(3):142-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 78109194 AU - Kirkbride CA AU - McAdaragh JP TI - Infectious agents associated with fetal and early neonatal death and abortion in swine. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - *Animals, Newborn MH - Enterovirus/isolation & purification MH - Female MH - Leptospira/isolation & purification MH - Pregnancy MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 780417 DP - 1978 Feb 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 480-3 SB - M CY - UNITED STATES IP - 4 VI - 172 JC - HAV AA - Author EM - 7806 AB - Laboratory examination of specimens from 824 porcine abortions over a 6- year period produced 320 (38.8%) diagnoses. Viruses were involved in 22% and bacteria in 16.5% of all cases. Enterovirus was the virus isolated most often (10.9%), followed by parvovirus (4.9%), reovirus (4.4%), pseudorabies virus (1%), and adenovirus (0.8%). Leptospirosis was the bacterial infection most commonly diagnosed (9.8%), with numerous miscellaneous bacterial and fungal infections making up the remainder (7.0%) of the infectious causes. PMID- 203567 CU - 93 SO - J Am Vet Med Assoc 1978 Feb 15;172(4):480-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 78129110 AU - Bey RF AU - Johnson RC TI - Protein-free and low-protein media for the cultivation of Leptospira. LA - Eng MH - Antigens, Bacterial MH - Comparative Study MH - *Culture Media MH - Leptospira/*growth & development/immunology/pathogenicity MH - Polysorbates MH - Serum Albumin, Bovine MH - Species Specificity MH - Support, U.S. Gov't, P.H.S. MH - Virulence PT - JOURNAL ARTICLE DA - 780517 DP - 1978 Feb IS - 0019-9567 TA - Infect Immun PG - 562-9 SB - M CY - UNITED STATES IP - 2 VI - 19 JC - GO7 AA - Author EM - 7807 AB - A protein-free medium composed of charcoal-detoxified Tweens (polysorbates), vitamins B12 and B1, inorganic salts, and organic buffer is described that supports the growth and subculture of pathogenic and saprophytic Leptospira. Growth was initiated from small inocula, and cell densities of 10(9) organisms per ml were attained. Antigenicity and immunogenicity of Leptospira cultivated in this medium were similar to those of cells cultivated in serum-containing media. The protein-free medium was converted to a low-protein medium by the addition of 0.1% bovine serum albumin. PMID- 631889 CU - 90 SO - Infect Immun 1978 Feb;19(2):562-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 78122989 AU - Ramphal R AU - Kluge R AU - Cohen V AU - Feldman R TI - Rocky Mountain spotted fever and jaundice. Two consecutive cases acquired in Florida and a review of the literature on this complication. LA - Eng MH - Case Report MH - Child MH - Diagnosis, Differential MH - Florida MH - Hepatitis, Viral, Human/diagnosis MH - Human MH - Jaundice/diagnosis/epidemiology/*etiology MH - Leptospirosis/diagnosis MH - Liver/pathology MH - Liver Function Tests MH - Male MH - Middle Age MH - Rocky Mountain Spotted Fever/*complications/diagnosis/epidemiology PT - JOURNAL ARTICLE DA - 780417 DP - 1978 Feb IS - 0003-9926 TA - Arch Intern Med PG - 260-63 SB - A SB - M CY - UNITED STATES IP - 2 VI - 138 JC - 7FS AA - Author EM - 7806 AB - Rocky mountain spotted fever is increasing in Florida, a state that has had few cases in the past. The typical clinical illness has been well described, but jaundice has been rarely reported. In two patients with illnesses resembling leptospirosis, jaundice appeared on the sixth and ninth day of illness, and peak bilirubin levels were between 7 and 9 mg/100 ml. Liver biopsy specimen from one patient showed a nonspecific hepatitis. Hemolysis and renal dysfunction may have contributed to the production of jaundice in these patients. Fourteen instances of jaundice were reported in 43 autopsied cases as of 1941, but since that time only rare mention of jaundice has been made. PMID- 626553 CU - 88 SO - Arch Intern Med 1978 Feb;138(2):260-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 80219130 AU - Wach T AU - Hencner Z TI - [Investigations into the activity of some leptospiral enzymes (author's transl)] LA - Pol MH - Alanine MH - Alanine Aminotransferase/*metabolism MH - Amino Acids/metabolism MH - Asparaginase/*metabolism MH - Comparative Study MH - Culture Media MH - English Abstract MH - Leptospira/*enzymology MH - Leptospira canicola/*enzymology RN - EC 2.6.1.2 (Alanine Aminotransferase) RN - EC 3.5.1.1 (Asparaginase) RN - 0 (Amino Acids) RN - 0 (Culture Media) RN - 6898-94-8 (Alanine) PT - JOURNAL ARTICLE DA - 800825 DP - 1978 IS - 0066-2240 TA - Ann Univ Mariae Curie Sklodowska [Med] PG - 125-35 CY - POLAND VI - 33 JC - 69M EM - 8010 PMID- 757922 CU - 92 TT - Badania nad aktywnoscia niektorych enzymow u leptospir. EA - A SO - Ann Univ Mariae Curie Sklodowska [Med] 1978;33:125-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 80219128 AU - Wach T AU - Hencner Z TI - [Free aminoacids in a liquid Korthof's medium during the culturing of various serotypes of Leptospirae (author's transl)] LA - Pol MH - Amino Acids/*metabolism MH - Comparative Study MH - *Culture Media MH - English Abstract MH - Leptospira/*growth & development/metabolism MH - Leptospira canicola/growth & development/metabolism MH - Leptospira interrogans/growth & development/metabolism MH - Species Specificity RN - 0 (Amino Acids) RN - 0 (Culture Media) PT - JOURNAL ARTICLE DA - 800825 DP - 1978 IS - 0066-2240 TA - Ann Univ Mariae Curie Sklodowska [Med] PG - 103-16 CY - POLAND VI - 33 JC - 69M EM - 8010 PMID- 757921 CU - 92 TT - Wolne aminokwasy w plynnym podlozu Korthofa w czasie hodowli roznych serotypow leptospir. EA - A SO - Ann Univ Mariae Curie Sklodowska [Med] 1978;33:103-16 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 79143885 AU - Lhuillier M TI - [Leptospiroses in Madagascar. (Bacteriological and serological study)] LA - Fre MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Human MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/immunology/*microbiology MH - Madagascar MH - Rodentia/microbiology MH - Species Specificity MH - Zoonoses PT - JOURNAL ARTICLE DA - 790516 DP - 1978 IS - 0020-2495 TA - Arch Inst Pasteur Madagascar PG - 429-39 SB - M CY - UNITED STATES IP - 1 VI - 46 JC - 7CZ EM - 7907 PMID- 747442 TT - Contribution a l'etude des leptospiroses a Madagascar. (Etude bacteriologique et serologique). SO - Arch Inst Pasteur Madagascar 1978;46(1):429-39 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 79120362 AU - Frohlich J TI - [Course studies in leptospirosis] LA - Ger MH - Human MH - Leptospirosis/*diagnosis MH - Seasons PT - JOURNAL ARTICLE DA - 790425 DP - 1978 IS - 0070-4067 TA - Verh Dtsch Ges Inn Med PG - 928-31 CY - GERMANY, WEST IP - 84 JC - X7W EM - 7906 PMID- 742150 TT - Verlaufsbeobachtungen bei Leptospirosen. SO - Verh Dtsch Ges Inn Med 1978;(84):928-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 79114629 AU - Oravec C AU - Kmety E TI - Antilymphoid activity of leptospiral exoproducts. LA - Eng MH - Animal MH - Cytotoxins/*toxicity MH - Guinea Pigs MH - Hamsters MH - Leptospira/*pathogenicity MH - Leptospirosis/*complications MH - Leukocyte Count MH - Lymphopenia/blood/*etiology MH - Mesocricetus PT - JOURNAL ARTICLE DA - 790428 DP - 1978 IS - 0028-2685 TA - Neoplasma PG - 565-8 SB - M CY - CZECHOSLOVAKIA IP - 5 VI - 25 JC - NVO AA - Author EM - 7906 AB - Intraperitoneal application of supernatant fluid of L. patoc caused a pronounced and transient fall in peripheral lymphocyte count of Syrian hamsters. Pathogenic and possible cancerologic aspects of this findings are discussed. PMID- 740056 CU - 90 SO - Neoplasma 1978;25(5):565-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 79055611 AU - Patorska-Mach E AU - Mierzejewska I AU - Kornas B TI - [Leptospirosis in the Chelm province] LA - Pol MH - Adult MH - Aged MH - English Abstract MH - Female MH - Human MH - Leptospirosis/complications/*epidemiology MH - Male MH - Middle Age MH - Poland MH - Rural Health PT - JOURNAL ARTICLE DA - 790126 DP - 1978 IS - 0033-2100 TA - Przegl Epidemiol PG - 323-9 CY - POLAND IP - 3 VI - 32 JC - Q8T EM - 7903 PMID- 715229 CU - 88 TT - Kretkowice z terenu wojewodztwa chelmskiego. EA - A SO - Przegl Epidemiol 1978;32(3):323-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 79040519 AU - Barsoum IS AU - Botros BA AU - Morcos MB TI - Equine leptospirosis with some clinical observations. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Egypt MH - Horse Diseases/*immunology/pathology MH - Horses MH - Leptospira/immunology MH - Leptospirosis/immunology/pathology/*veterinary MH - Perissodactyla PT - JOURNAL ARTICLE DA - 781227 DP - 1978 IS - 0003-4193 TA - Ann Rech Vet PG - 115-8 SB - M CY - FRANCE IP - 1 VI - 9 JC - 5ZT AA - Author EM - 7902 AB - In a serologic survey on equine leptospirosis in Egypt, the following incidences of leptospiral serosensitivity were found: 1. Hospitalised horses 65/113 (57.5 %). 2. Hospitalised donkeys 90/125 (72.0 %). 3. Apparently healthy horses 21/72 (29.1 %). Sera of these animals were mostly reacting to serotypes butembo, pomona, icterohemorragiae, and grippotyphosa. Equine in Egypt are close animals to humans and may constitute a potential source of leptospiral infection. From the clinical point of view, it is very possible that ocular, hoof lesions and icterus in equines would be expected with leptospiral titres. PMID- 707959 SO - Ann Rech Vet 1978;9(1):115-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 79022071 AU - Zeigler JA AU - Kubica KM AU - Jones RH TI - Immunization against leptospirosis: continued vaccine trials in hamsters using strains isolated from Barbados. LA - Eng MH - Animal MH - Barbados MH - Female MH - Hamsters MH - *Immunization MH - Leptospira interrogans/*immunology/isolation & purification MH - Leptospirosis/*immunology MH - Serotyping MH - Support, U.S. Gov't, Non-P.H.S. MH - Vaccines, Attenuated/*immunology PT - JOURNAL ARTICLE DA - 781220 DP - 1978 TA - Bull Pan Am Health Organ PG - 130-3 CY - UNITED STATES IP - 2 VI - 12 JC - BSB AA - Author EM - 7902 AB - Heated whole-cell suspensions of L. interrogans serotype copenhageni strains isolated from the field in Barbados have proved to be protective immunogens against experimental leptospirosis. PMID- 698450 SO - Bull Pan Am Health Organ 1978;12(2):130-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 79017740 AU - Lamy V TI - [A case of acute renal insufficiency caused by icterohemorrhagic leptospirosis] LA - Fre MH - Adult MH - Case Report MH - English Abstract MH - Hemodialysis MH - Human MH - Kidney Failure, Acute/*etiology/therapy MH - Leptospira interrogans MH - Male MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 781122 DP - 1978 IS - 0001-5512 TA - Acta Clin Belg PG - 55-61 CY - BELGIUM IP - 1 VI - 33 JC - 0KW EM - 7901 PMID- 696162 TT - A propos d'un cas d'insuffisance renale aigue due a une leptospirose icterohemorragique. EA - A SO - Acta Clin Belg 1978;33(1):55-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 79013319 AU - Kucharska-Demczuk K AU - Trzaska B TI - [Cerebrospinal fluid cytology in meningitis caused by Leptospira] LA - Pol MH - Adolescence MH - Adult MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Meningitis/*cerebrospinal fluid/etiology MH - Middle Age PT - JOURNAL ARTICLE DA - 781129 DP - 1978 IS - 0033-2100 TA - Przegl Epidemiol PG - 195-202 CY - POLAND IP - 2 VI - 32 JC - Q8T EM - 7901 PMID- 693962 TT - Obraz cytologiczny plynu mozgowo-rdzeniowego w leptospirowym zapaleniu opon. EA - A SO - Przegl Epidemiol 1978;32(2):195-202 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 79013318 AU - Pawlicka-Kurek H TI - [Leptospirosis in the Katowice region in the years 1968-1976] LA - Pol MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Poland MH - Seasons MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 781129 DP - 1978 IS - 0033-2100 TA - Przegl Epidemiol PG - 189-93 CY - POLAND IP - 2 VI - 32 JC - Q8T EM - 7901 PMID- 693961 CU - 88 TT - Leptospirozy w woj. katowickim w latach 1968--1976. EA - A SO - Przegl Epidemiol 1978;32(2):189-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 78149422 AU - Sebek Z AU - Blazek K AU - Valova M AU - Amin A TI - Further results of serological examination of domestic animals for leptospirosis in Afghanistan. LA - Eng MH - Afghanistan MH - Animal MH - Animals, Domestic/*immunology MH - Antibodies, Bacterial/*analysis MH - Buffaloes/immunology MH - Camels/immunology MH - Cattle/immunology MH - Goats/immunology MH - Leptospira/*immunology MH - Sheep/immunology PT - JOURNAL ARTICLE DA - 780628 DP - 1978 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 17-22 CY - CZECHOSLOVAKIA IP - 1 VI - 25 JC - F2T AA - Author EM - 7808 AB - The authors examined serologically 329 specimens of domestic animals from 8 provinces of Afghanistan for the incidence of leptospirosis. They detected in 15.8% of the animals examined antibodies against Leptospira in titres of 1 : 800 and higher: in 6.4% with serotypes of the serogroup Hebdomadis, 5.5%--Tarassovi, 2.7%--Grippotyphosa, 2.4%-- Pomona, 2.1% Javanica, 1.5%--Icterohaemorrhagiae, 0.6% each--Canicola, Ballum, Bataviae, 0.3%--Pyrogenes. Positivity was highest in the buffalo--55.0%, camel--10 of the 18 animals examined, and cattle-- 25.5%. It was considerably lower in sheep--2.3% and goat--3.2%; also positive was one of the 6 zebus examined. PMID- 640518 SO - Folia Parasitol (Praha) 1978;25(1):17-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78139530 AU - Sulzer AJ AU - Sulzer KR AU - Cantella RA AU - Colichon H AU - Latorre CR AU - Welch M TI - Study of coinciding foci of malaria and leptospirosis in the Peruvian Amazon area. LA - Eng MH - Antibodies/analysis MH - *Disease Reservoirs MH - Human MH - Leptospirosis/*epidemiology/immunology MH - Malaria/*epidemiology/immunology MH - Peru PT - JOURNAL ARTICLE DA - 780508 DP - 1978 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 76-83 SB - M CY - ENGLAND IP - 1 VI - 72 JC - WBU AA - Author EM - 7807 AB - A hyperendemic malaria focus, found in 1973 in a secluded valley in South-eastern Peru, was restudied in 1975. Tests for antibodies to Plasmodium and Leptospira were performed on blood serum and blood slides collected at three locations on the Rio Ene and confluent streams and at two locations in the neighbouring highlands. The hyperendemic focus of P. vivax-P. malariae found at Mission Cutivirini in 1973 was confirmed in this study. Another hyperendemic focus of predominantly P. vivax was found at the village of Saoreni. Lesser amounts of malaria were found at other locations. Serology indicated past or present contact with Leptospira of from 50 to 75% of individuals at all locations. The two hyperendemic malaria foci therefore were embedded in a much larger hyperendemic focus of leptospirosis. The value of the indirect immunofluorescence test for malarial antibodies as a sero-epidemiological tool was emphasized by this study. PMID- 635982 CU - 88 SO - Trans R Soc Trop Med Hyg 1978;72(1):76-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 78125343 AU - Higgins R AU - Cayouette P TI - Serological diagnosis of leptospirosis in the Province of Quebec. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Leptospirosis/diagnosis/*veterinary MH - Quebec MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 780520 DP - 1978 Jan IS - 0008-5286 TA - Can Vet J PG - 13-6 CY - CANADA IP - 1 VI - 19 JC - CLS EM - 7807 PMID- 630523 SO - Can Vet J 1978 Jan;19(1):13-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 78110526 AU - Pochanugool C AU - Sitprija V TI - Hyperbilirubinemic renal failure in tropical disease: Treatment with exchange transfusion. LA - Eng MH - Adult MH - Case Report MH - *Exchange Transfusion, Whole Blood MH - Human MH - Hyperbilirubinemia/etiology/*therapy MH - Kidney Failure, Acute/etiology/*therapy MH - Leptospirosis/complications MH - Malaria/complications MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 780426 DP - 1978 Jan IS - 0025-7036 TA - J Med Assoc Thai PG - 75-7 CY - THAILAND VI - 61 Suppl 1 JC - IZR EM - 7806 PMID- 627809 SO - J Med Assoc Thai 1978 Jan;61 Suppl 1:75-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 78121595 AU - Anderson DC AU - Geistfeld JG AU - Maetz HM AU - Patton CM AU - Kaufmann AF TI - Leptospirosis in zoo workers associated with bears. LA - Eng MH - Adult MH - Animal MH - Animals, Zoo/*microbiology MH - Bears/*microbiology MH - Carnivora/*microbiology MH - Case Report MH - Human MH - Male MH - Occupational Diseases/*transmission MH - Weil's Disease/*transmission/veterinary PT - JOURNAL ARTICLE DA - 780417 DP - 1978 Jan IS - 0002-9637 TA - Am J Trop Med Hyg PG - 210-1 SB - A SB - M CY - UNITED STATES IP - 1 Pt 1 VI - 27 JC - 3ZQ AA - Author EM - 7806 AB - Leptospirosis due to Leptospira interrogans serovar icterohaemorrhagiae was diagnosed in two zoo animal keepers. The implicated source of infection was bear cubs that had microscopic agglutination antibody titers to leptospires of the Icterohaemorrhagiae serogroup. PMID- 626276 CU - 90 SO - Am J Trop Med Hyg 1978 Jan;27(1 Pt 1):210-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 78115699 AU - Borirakchanyavat V AU - Vongsthongsri M AU - Sitprija V TI - Furosemide and acute renal failure. LA - Eng MH - Adult MH - Comparative Study MH - Creatinine/metabolism MH - Diuresis/drug effects MH - Female MH - Furosemide/*therapeutic use MH - Human MH - Kidney Failure, Acute/*drug therapy/etiology MH - Leptospirosis/complications MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 780417 DP - 1978 Jan IS - 0032-5473 TA - Postgrad Med J PG - 30-2 CY - ENGLAND IP - 627 VI - 54 JC - PFX AA - Author EM - 7806 AB - High dose of intravenous furosemide (2 g/24 hr) was given to six patients with acute renal failure due to leptospirosis. The results, based on urine flow, changes in serum creatinine and creatinine clearance, were compared with a control group of eight patients with the same disease and comparable degree of renal failure. Excellent diuresis was observed following furosemide therapy but renal function and the clinical course of the disease were unaltered. The duration of renal failure was the same in both groups. PMID- 625455 SO - Postgrad Med J 1978 Jan;54(627):30-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 79102518 AU - Parnas J TI - Leptospirosis: ecology, epidemiology and prophylactic measures. LA - Eng MH - Africa MH - Animal MH - Asia MH - Australia MH - Disease Vectors MH - Ecology MH - Europe MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/prevention & control MH - North America MH - South America PT - JOURNAL ARTICLE DA - 790328 DP - 1978 Jan-Feb IS - 0003-472X TA - Ann Sclavo PG - 71-105 CY - ITALY IP - 1 VI - 20 JC - 65C EM - 7905 PMID- 570020 CU - 88 SO - Ann Sclavo 1978 Jan-Feb;20(1):71-105 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 78227784 AU - Straton A AU - Straton C AU - Bercovici C AU - Beldiman N AU - Stefanescu E AU - Anton N AU - Tudor G AU - Vrabie S AU - Gavris L TI - [Study of the natural reservoir of Leptospira in the Danube Delta. III. Region of the Sfintu Gheorghe branch] LA - Rum MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - *Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira MH - Leptospirosis/*epidemiology MH - Rats MH - Rodent Diseases/epidemiology MH - Romania MH - Swine MH - Swine Diseases/epidemiology MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 780930 DP - 1978 Jan-Mar IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 69-72 CY - ROMANIA IP - 1 VI - 82 JC - SHP EM - 7811 PMID- 566949 CU - 88 TT - Studiul rezervorului natural de leptospire din Delta Dunarii. Nota iii. Zona bratului Sfintu Gheorghe. EA - A SO - Rev Med Chir Soc Med Nat Iasi 1978 Jan-Mar;82(1):69-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 78150405 AU - Sullivan JF AU - Songer JR AU - Estrem IE TI - Laboratory-acquired infections at the National Animal Disease Center 1960--1976. LA - Eng MH - Animal MH - Animal Diseases/*transmission MH - Bacterial Infections/epidemiology/transmission MH - Human MH - Laboratory Infection/*epidemiology/etiology MH - Research MH - United States PT - JOURNAL ARTICLE DA - 780612 DP - 1978 Jan IS - 0017-9035 TA - Health Lab Sci PG - 58-64 SB - M CY - UNITED STATES IP - 1 VI - 15 JC - G2C AA - Author EM - 7808 AB - Experience with exposure to, or infection with pathogenic agents at the National Animal Disease Center is summarized. A total of 60 laboratory- associated exposures to infectious disease agents were reported. Forty- nine exposures resulted from known accidents, but the other 11 were identified only after the development of clinical or serological manifestations of infection. Eighteen cases of laboratory-acquired infections were reviewed. Brucellosis, the most frequently reported laboratory-acquired infection, accounted for one-half of the cases summarized. Three cases of leptospirosis, two cases of Newcastle disease, two cases of ringworm, and a single infection with Mycobacterium bovis and with Salmonella arizonae were also encountered. The most frequently reported causes of exposure were: auto-inoculation or spray exposure associated with the use of the hypodermic syringe, cuts or lacerations, direct contact with infected animals, and mouth pipetting. Although the infecting event could not be identified in 11 infections, presumptive evidence suggests aerogenic transmission as a probable route of exposure in a number of such cases. PMID- 565343 CU - 88 SO - Health Lab Sci 1978 Jan;15(1):58-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 78063545 AU - Nervig RM AU - Ellinghausen HC Jr TI - Viability of Leptospira interrogans serotype grippotyphosa in swine urine and blood. LA - Eng MH - Animal MH - Anticoagulants/pharmacology MH - Bacteriological Techniques MH - Blood Bactericidal Activity MH - Edetic Acid/pharmacology MH - Filtration MH - Leptospira interrogans/*growth & development MH - Serum Albumin, Bovine MH - Swine/blood/*microbiology/urine MH - Urine/microbiology MH - Virulence PT - JOURNAL ARTICLE DA - 780218 DP - 1978 Jan IS - 0010-8901 TA - Cornell Vet PG - 70-7 SB - M CY - UNITED STATES IP - 1 VI - 68 JC - DRI AA - Author EM - 7804 AB - Normal swine urine, devoid of its microbial flora, diminished the viability and virulence of Leptospira interrogans serotype grippotyphosa. Bovine serum albumin diluent effectively offset the urine's deleterious effects. Membrane filtration (0.45 micrometer) rendered urine free of bacteria, but permitted passage of limited numbers of leptospires. Most of the commonly used anticoagulants did not alter viability of grippotyphosa in whole blood. However, EDTA significantly reduced the number of viable cells. PMID- 412643 CU - 91 SO - Cornell Vet 1978 Jan;68(1):70-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 79040595 AU - Canale-Parola E TI - Motility and chemotaxis of spirochetes. LA - Eng MH - Bacterial Proteins/analysis MH - Borrelia/physiology MH - *Chemotaxis MH - DNA, Bacterial/analysis MH - Leptospira/physiology MH - Models, Biological MH - Movement MH - Organoids/ultrastructure MH - Spirochaeta/physiology MH - Spirochaetaceae/analysis/cytology/*physiology MH - Support, U.S. Gov't, P.H.S. MH - Treponema/physiology MH - Viscosity PT - JOURNAL ARTICLE PT - REVIEW DA - 781227 DP - 1978 IS - 0066-4227 TA - Annu Rev Microbiol PG - 69-99 SB - M CY - UNITED STATES VI - 32 JC - 6DV EM - 7902 RF - 128 PMID- 360979 CU - 90 SO - Annu Rev Microbiol 1978;32:69-99 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 79201907 AU - Schmitz JA AU - Coles BM AU - Burdett R AU - Reynolds GE TI - A study on the causes of abortion/stillbirth/perinatal lamb loss in Oregon. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - *Animals, Newborn MH - Female MH - Fetal Death/etiology/*veterinary MH - Leptospirosis/veterinary MH - Oregon MH - Pregnancy MH - Sheep MH - Sheep Diseases/*etiology PT - JOURNAL ARTICLE DA - 790816 DP - 1978 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 414-6 CY - UNITED STATES IP - 82 JC - PY5 EM - 7910 PMID- 287109 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1978;(82):414-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 79201883 AU - Brown AL TI - Standardization of leptospiral testing. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antibodies, Bacterial MH - Antigens, Bacterial MH - Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*immunology MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 790816 DP - 1978 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 191-204 CY - UNITED STATES IP - 82 JC - PY5 EM - 7910 PMID- 287089 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1978;(82):191-204 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 78126292 AU - Schultz RD TI - Current canine vaccination programs: results of a questionnaire. LA - Eng MH - Animal MH - Bordetella Infections/veterinary MH - Brucellosis/veterinary MH - Distemper/prevention & control MH - Dog Diseases/*prevention & control MH - Dogs MH - Hepatitis, Infectious Canine/prevention & control MH - Leptospirosis/veterinary MH - Paramyxoviridae Infections/veterinary MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 780517 DP - 1978 Jan IS - 0010-8901 TA - Cornell Vet PG - 62-9 SB - M CY - UNITED STATES VI - 68 Suppl 7 JC - DRI EM - 7807 PMID- 204454 CU - 96 SO - Cornell Vet 1978 Jan;68 Suppl 7:62-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 85006622 AU - Pickett BW AU - Berndtson WE AU - Sullivan JJ TI - Influence of seminal additives and packaging systems on fertility of frozen bovine spermatozoa. LA - Eng MH - alpha-Amylase/pharmacology MH - beta-Amylase/pharmacology MH - Animal MH - Antibiotics/pharmacology MH - Carbohydrates/pharmacology MH - Cattle MH - *Fertility/drug effects MH - Freezing MH - Gases/pharmacology MH - Glucuronidase/pharmacology MH - Insemination, Artificial/veterinary MH - Male MH - Semen Preservation/methods/*veterinary MH - Sperm Motility MH - Spermatozoa/drug effects/*physiology MH - Temperature RN - EC 3.2.1.1 (alpha-Amylase) RN - EC 3.2.1.2 (beta-Amylase) RN - EC 3.2.1.31 (Glucuronidase) RN - 0 (Antibiotics) RN - 0 (Gases) PT - JOURNAL ARTICLE PT - REVIEW DA - 841109 DP - 1978 IS - 0021-8812 TA - J Anim Sci PG - 12-47 SB - M CY - UNITED STATES VI - 47 Suppl 2 JC - HC7 AA - Author EM - 8501 AB - The following recommendations and conclusions are based upon results of fertility and laboratory studies, and general trends from field investigations. Fertility results due to the addition of enzymes have been variable and contradictory. Flushing of ampules with dry, gaseous nitrogen prior to filling has become a routine practice in processing semen to be frozen. For control of Vibrio fetus and Leptospira pomona, 2,000 micrograms of streptomycin and 1,000 u polymyxin B sulfate should be added per milliliter of raw semen immediately after collection. The extender for initial dilution should contain the same concentration of antibiotics used for raw semen plus 500 u penicillin. The glycerol portion of the extender should contain 500 u penicillin per milliliter. The effect of addition of sugars on fertility has been highly variable. The primary beneficial effect is probably due to their cryoprotective properties. A myriad of concoctions have been added to bovine semen and the results have been highly variable with respect to both motility and fertility. Results of subsequent experiments have rarely proven that addition of exotic compounds or mixtures has been of value. Higher mean fertility was obtained with semen in straws in 14 of 21 comparisons with ampules. The differences in favor of straws ranged from 1.1 to 18.9; while the range in favor of ampules was .1 to 4.4 percentage points. Fertility obtained with pellets has ranged from minus 12.8 to plus 11.9 percentage points in nonreturn rate (NR), compared to the corresponding NR with semen in ampules. Fertility of semen in ampules was higher in five of eight studies. Fertility of pelleted semen has ranged from minus 9.5 to plus 6.0 percentage points compared with straws. Fertility was higher for semen in pellets in only one of five investigations. Pellets should not be used until the potential for pathogenic contamination and exchange of spermatozoa among pellets is eliminated. There is a potential for higher fertility with semen in straws as compared to other packaging systems, but the issue of liquid nitrogen (LN) entry and possible contamination of semen should be further investigated. In general, fertility obtained with semen frozen in the .25 ml straw has been equal to or higher than semen in larger packages. However, they cannot be unequivocally recommended due to other considerations. From laboratory studies, it appears that greater spermatozoan survival is obtained when semen frozen in straws is thawed in water at 35 C or above.(ABSTRACT TRUNCATED AT 400 WORDS) RF - 179 PMID- 162535 CU - 92 NP - X SO - J Anim Sci 1978;47 Suppl 2:12-47 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 79192653 AU - Vasilevska M TI - Acrylamide electrophoresis of water-soluble proteins from leptospiras. LA - Eng MH - Electrophoresis, Disc MH - Leptospira/classification/*metabolism MH - Proteins/*metabolism MH - Solubility PT - JOURNAL ARTICLE DA - 790816 DP - 1978 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 38-41 CY - BULGARIA IP - 4 VI - 20 JC - F19 EM - 7910 PMID- 109376 CU - 91 SO - Folia Med (Plovdiv) 1978;20(4):38-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 79093300 AU - Adachi Y AU - Yanagawa R TI - Nature of antigenic determinant of serovar-specific antigen of Leptospira interrogans serovar hebdomadis. LA - Eng MH - Amino Acids/analysis MH - Amino Sugars/analysis MH - Antigens, Bacterial/*analysis/genetics MH - Bacterial Proteins/analysis MH - Carbohydrates/analysis MH - Complement Fixation Tests MH - Epitopes MH - Leptospira interrogans/genetics/*immunology MH - Lipids/analysis MH - Variation (Genetics) PT - JOURNAL ARTICLE DA - 790324 DP - 1978 TA - Microbiol Immunol PG - 523-33 SB - M CY - JAPAN IP - 9 VI - 22 JC - MX7 AA - Author EM - 7905 AB - The nondialyzable delipidized serovar-specific main antigen (NDTM antigen) of Leptospira interrogans serovar hebdomadis strain Hebdomadis (a variant which can grow in a synthetic medium) showed a strong inhibition of the complement fixation between the serovar-specific main (TM) antigen of this strain and the homologous antiserum. The inhibitory effect of the NDTM antigen was completely lost by treating the antigen with proteolytic enzymes, and the fractions of TM antigen containing amino sugar, neutral sugars, and lipids did not show any inhibition of complement fixation, indicating that the antigenic determinant of this strain is related to proteins. NDTM antigen contained more hydrophilic amino acids than hydrophobic amino acids, whereas TM antigen contained more hydrophobic amino acids than hydrophilic amino acids. The amino acid compositions of NDTM antigens of hebdomadis strain Hebdomadis (variant) and kremastos strain Kyoto, which belonged to the same serogroup, were considerably similar. Difference was found in the amounts of methionine, arginine, lysine and glutamine acid. PMID- 83525 CU - 95 SO - Microbiol Immunol 1978;22(9):523-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 79051569 AU - Volina EG AU - Sarukhanova LE TI - [Cultivation of Leptospira on the color agar medium] LA - Rus MH - Agar MH - *Culture Media MH - English Abstract MH - Leptospira/*growth & development MH - Phenolsulfonphthalein PT - JOURNAL ARTICLE DA - 790115 DP - 1978 IS - 0023-6748 TA - Lab Delo PG - 633-5 CY - USSR IP - 10 JC - KYU EM - 7903 PMID- 81922 CU - 95 TT - Kul'tivirovanie leptospir na tsvetnoi agarovoi srede. EA - A SO - Lab Delo 1978;(10):633-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 80219129 AU - Wach T AU - Hencner Z TI - [Total nitrogen, alpha-amine nitrogen and pH in the cultural filtrates of various leptospiral serotypes being cultured in a liquid Korthof's medium (author's transl)] LA - Pol MH - Comparative Study MH - *Culture Media MH - English Abstract MH - Hydrogen-Ion Concentration MH - Leptospira/growth & development/*metabolism MH - Leptospira canicola/growth & development/metabolism MH - Leptospira interrogans/growth & development/metabolism MH - Nitrogen/analysis/*metabolism MH - Species Specificity RN - 0 (Culture Media) RN - 7727-37-9 (Nitrogen) PT - JOURNAL ARTICLE DA - 800825 DP - 1978 IS - 0066-2240 TA - Ann Univ Mariae Curie Sklodowska [Med] PG - 117-23 CY - POLAND VI - 33 JC - 69M EM - 8010 PMID- 44830 CU - 94 TT - Azot calkowity, azot alpha-aminowy, pH w przesaczach hodowli roznych serotypow leptospir na plynnym podlozu Korthofa. EA - A SO - Ann Univ Mariae Curie Sklodowska [Med] 1978;33:117-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 78099534 AU - de Brito T AU - Trench Vieira W AU - D'Agostino Dias M TI - Jaundice in typhoid hepatitis: a light and electron microscopy study based on liver biopsies. LA - Eng MH - Adolescence MH - Adult MH - Biopsy/methods MH - Child, Preschool MH - Female MH - Hepatitis/complications/*pathology MH - Human MH - Jaundice/etiology/*pathology MH - Male MH - Middle Age MH - Typhoid/complications/*pathology PT - JOURNAL ARTICLE DA - 780310 DP - 1977 Dec IS - 0300-970X TA - Acta Hepatogastroenterol (Stuttg) PG - 426-33 SB - M CY - GERMANY, WEST IP - 6 VI - 24 JC - 0TG AA - Author EM - 7805 AB - Light and electron microscopy study of fourteen liver biopsies in typhoid fever disclosed a mild hepatitis in which there is marked reticulo-endothelial hyperplasia, with many lymphoid cells in the hepatic sinusoids. The hepatic cell lesion was non specific, manifested by reticulum endoplasmic dilatation, mitochondrial alteration and biliary canaliculus injury. Such findings were particularly evident in the jaundiced patients.Jaundice was, in our series, a more frequent complication of acute typhoid fever than commonly reported. Usually it is of short duration and the serum bilirubin was not markedly elevated. However, there were instances when the jaundice was so accentuated as to lead the clinician to a first diagnosis of virus hepatitis or leptospirosis. The pathogenesis of the intrahepatic cholestasis in typhoid fever is still obscure, but apparently it is, as has been described in other infectious diseases, due to an injury of the bile secretory apparatus brought out by the bacillary endotoxin. PMID- 602618 SO - Acta Hepatogastroenterol (Stuttg) 1977 Dec;24(6):426-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 78097621 AU - Glazebrook JS AU - Campbell RS AU - Hutchinson GW TI - The pathology of feral rodents in North Queensland. II. Studies on zoonotic infections. LA - Eng MH - Animal MH - Australia MH - Disease Reservoirs MH - Helminthiasis/veterinary MH - Human MH - Leptospirosis/veterinary MH - Mice MH - Rats MH - Rodent Diseases/*epidemiology/parasitology MH - Rodentia MH - Toxoplasmosis, Animal/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 780310 DP - 1977 Dec IS - 0303-4208 TA - Tropenmed Parasitol PG - 545-51 SB - M CY - GERMANY, WEST IP - 4 VI - 28 JC - WGM EM - 7805 PMID- 601858 CU - 88 SO - Tropenmed Parasitol 1977 Dec;28(4):545-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 78086554 AU - Caldas EM AU - Doria JD AU - Martins MA TI - Immunological inquiry for the epidemiology of leptospirosis in Canis familiaris in Salvador, Bahia, Brazil. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Brazil MH - Dog Diseases/*epidemiology/immunology MH - Dogs MH - Female MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Male MH - Serotyping MH - Weil's Disease/epidemiology/immunology/veterinary PT - JOURNAL ARTICLE DA - 780329 DP - 1977 Dec IS - 0377-0168 TA - Int J Zoonoses PG - 103-10 SB - M CY - TAIWAN IP - 2 VI - 4 JC - GTK AA - Author EM - 7805 AB - A total of 430 dogs were immunologically examined in Salvador, Bahia, Brazil, and 21.6% of them were positive. The animals were selected through an aleatory pattern, according to the division of the City in 18 residential zones a division which had been established by the vaccination campaign against canis hydrophobia. The serotypes icterohemorrhagiae and canicola were the most frequently registered. Between the sexes, the male presented the highest index of positivity, though the difference wasn't statistically significant. The period of age ranging from 12 to 48 months comprised 67.7% of the investigations. Mestizo dogs presented a higher frequency of positivity than any other race and the areas of Nordeste de Amaralina, Liberdade and Quintas showed the greatest percentages of positive dogs. PMID- 598976 CU - 88 SO - Int J Zoonoses 1977 Dec;4(2):103-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 78082032 AU - Carpio M AU - Wobeser G AU - Iversen J TI - Leptospira interrogans serotype pomona in Saskatchewan: isolation from a naturally infected striped skunk. LA - Eng MH - Animal MH - Carnivora/*microbiology MH - Kidney/microbiology MH - Leptospira interrogans/*isolation & purification MH - Saskatchewan MH - Skunks/*microbiology PT - JOURNAL ARTICLE DA - 780329 DP - 1977 Dec IS - 0008-4166 TA - Can J Microbiol PG - 1654-6 SB - M CY - CANADA IP - 12 VI - 23 JC - CJ3 AA - Author EM - 7805 AB - Leptospira interrogans serotype pomona was isolated from the kidneys of a normal striped skunk (Mephitis mephitis hudsonicus) collected near Kindersley, Saskatchewan. Although there were no gross lesions, small foci of chronic interstitial nephritis were observed microscopically. This is the first reported isolation of serotype pomona for the prairie provinces. PMID- 597790 CU - 90 SO - Can J Microbiol 1977 Dec;23(12):1654-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 78133457 AU - Imamura S AU - Matsui H AU - Kasao M AU - Ashizawa Y TI - Use of freeze-dried sensitized erythrocytes in indirect hemagglutination test for serodiagnosis of leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Erythrocytes/*immunology MH - Freeze Drying MH - Human MH - Leptospirosis/*diagnosis MH - Sheep/immunology MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 780508 DP - 1977 Dec IS - 0021-5031 TA - Jpn J Exp Med PG - 441-4 SB - M CY - JAPAN IP - 6 VI - 47 JC - KJR AA - Author EM - 7807 AB - The indirect hemagglutination (HA) test using freeze-dried tanned formalinized sheep erythrocytes sensitized with deoxycholate-extracted leptospiral antigen was investigated for its applicability to serodiagnosis of leptospirosis. The sensitized erythrocytes suspension containing an adequate concentration of glycine was lyophilized and used for the HA test. The lyophilized sensitized cells are rehydrated after at least 10 months storage without any loss of HA titer. The sensitivity of such cell suspension tested on sera from cases of leptospirosis equals that of the suspension before freeze-drying. PMID- 564982 CU - 85 SO - Jpn J Exp Med 1977 Dec;47(6):441-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 78224291 AU - Tyndel PE TI - Probable leptospiral abortion in mares [letter] LA - Eng MH - *Abortion, Veterinary MH - Animal MH - Female MH - *Horse Diseases MH - Horses MH - Leptospirosis/*veterinary MH - Pregnancy PT - LETTER DA - 780915 DP - 1977 Dec IS - 0048-0169 TA - N Z Vet J PG - 401 CY - NEW ZEALAND IP - 12 VI - 25 JC - OBZ EM - 7811 PMID- 276751 CU - 91 SO - N Z Vet J 1977 Dec;25(12):401 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 78095588 AU - Olivares Martin J AU - Gomez Andres A AU - Luna Morales A AU - Palazon Azorin JM AU - Lopez Fernandez P AU - Pascual Megias A AU - Plazas Ruiz J TI - [Icterohaemorrhagic leptoipirosis. Report of 2 cases] LA - Spa MH - Adult MH - Case Report MH - Female MH - Human MH - Leptospira interrogans/isolation & purification MH - Male MH - Pregnancy MH - Pregnancy Complications, Infectious/microbiology MH - *Weil's Disease/microbiology PT - JOURNAL ARTICLE DA - 780310 DP - 1977 Nov 30 IS - 0014-2565 TA - Rev Clin Esp PG - 439-42 CY - SPAIN IP - 4 VI - 147 JC - RNL EM - 7805 PMID- 601306 TT - Leptospirosis icterohemorragica. Presentacion de dos casos. SO - Rev Clin Esp 1977 Nov 30;147(4):439-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 78080530 AU - Cacciapuoti B TI - Leptospiras as causative organisms of meningitis. LA - Eng MH - Adult MH - Age Factors MH - English Abstract MH - Human MH - Italy MH - Leptospirosis/*complications/epidemiology MH - Meningitis/epidemiology/*etiology MH - Middle Age MH - Seasons PT - JOURNAL ARTICLE DA - 780321 DP - 1977 Nov 30 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 422-8 SB - M CY - ITALY IP - 5 VI - 56 JC - AKG AA - Author EM - 7805 AB - Data concerning the incidence of meningeal syndromes during the course of leptospirosis are analyzed, in relation to the Italian epidemiological situation in the years 1973-1976. From this analysis, some characteristic aspects concerning meningitis from leptospiras emerge. Specifically: the remarkable frequency of meningeal syndromes in leptospirosis; the greater incidence of the syndrome among young people; the neurotropism common to all serotypes of leptospira observed in Italy. These data suggest to extend the search for leptospiroses in all forms of the so called aseptic meningitis in order to determine better the actual incidence of leptospiroses in meningeal syndromes. PMID- 597393 CU - 88 EA - A SO - Boll Ist Sieroter Milan 1977 Nov 30;56(5):422-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78025355 AU - Krauss N TI - [Microsymptoms in leptospirosis] LA - Ger MH - Adult MH - Case Report MH - Confusion MH - English Abstract MH - Epistaxis/etiology MH - Fever/etiology MH - Headache/etiology MH - Herpes Labialis/etiology MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*complications MH - Male MH - Muscles MH - Pain/etiology MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 771229 DP - 1977 Nov 17 IS - 0015-8178 TA - Fortschr Med PG - 2637-9 SB - M CY - GERMANY, WEST IP - 43 VI - 95 JC - F62 AA - Author EM - 7802 AB - Leptospirosis is not an exotic disease, still it is seen more frequent in southern countries. Microsymptoms, such as supraorbital headache, muscle pain in the legs, herpes naso-labialis or axillaris (often symmetrical), pharynxenanthema, fugitive rash, epistaxis, confusion, etc., are very important for early diagnosis. An intradermal test for early diagnosis was developed and is described here. PMID- 914223 CU - 90 TT - Mikrosymptome bei Leptospirose. EA - A SO - Fortschr Med 1977 Nov 17;95(43):2637-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 78029344 AU - Andrew ED AU - Marrocco GR TI - Leptospirosis in New England. LA - Eng MH - Adult MH - Animal MH - Antibodies, Bacterial/analysis MH - Blood/microbiology MH - Case Report MH - Dairying MH - Fatigue MH - Gastroenteritis/diagnosis MH - Human MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*epidemiology/transmission MH - Male MH - Meningitis/diagnosis MH - Middle Age MH - New England MH - Zoonoses PT - JOURNAL ARTICLE DA - 771229 DP - 1977 Nov 7 IS - 0098-7484 TA - JAMA PG - 2027-8 SB - A SB - M CY - UNITED STATES IP - 19 VI - 238 JC - KFR AA - Author EM - 7802 AB - Although rarely reported in humans in New England, leptospirosis is enzootic in western and central Massachusetts. Recently there were three cases of Leptospira interrogans, serotype var pomona, in Easthampton, Mass. Our study and others indicate a potential for waterborne epidemics in humans. RO - M:LBR PMID- 578899 LR - 781026 CU - 88 SO - JAMA 1977 Nov 7;238(19):2027-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 78007591 AU - Humphry T AU - Sanders S AU - Stadius M TI - Leptospirosis mimicking MLNS [letter] LA - Eng MH - Case Report MH - Child, Preschool MH - Diagnosis, Differential MH - Female MH - Human MH - Leptospirosis/*diagnosis MH - Lymphatic Diseases/*diagnosis MH - Mucocutaneous Lymph Node Syndrome/*diagnosis PT - LETTER DA - 771130 DP - 1977 Nov IS - 0022-3476 TA - J Pediatr PG - 853-4 SB - A SB - M CY - UNITED STATES IP - 5 VI - 91 JC - JLZ EM - 7801 PMID- 909036 CU - 91 SO - J Pediatr 1977 Nov;91(5):853-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 78237380 AU - Le Bras J AU - Guyer B AU - Sulzer C AU - Mailloux M TI - [Anademic focus of leptospirosis at Fondem (U.R. of Cameroon)] LA - Fre MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Cameroon MH - Child MH - Disease Outbreaks MH - Disease Reservoirs MH - English Abstract MH - Female MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Seasons MH - Sex Factors MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 781027 DP - 1977 Nov-Dec IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 569-83 SB - M CY - FRANCE IP - 6 VI - 70 JC - C4G EM - 7812 PMID- 615682 CU - 88 TT - Le foyer anademique de leptospiroses de Fontem (R. U. du Cameroun). EA - A SO - Bull Soc Pathol Exot Filiales 1977 Nov-Dec;70(6):569-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 78180219 AU - Nery LE AU - de Paula AB AU - Nakatani J AU - dos Santos ML AU - Ratto OR TI - Clinical, radiological and functional pulmonary manifestations in patients with leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Diagnosis, Differential MH - Female MH - Human MH - Kidney Diseases/diagnosis/microbiology MH - Leptospirosis/*diagnosis MH - Lung Diseases/diagnosis/microbiology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 780724 DP - 1977 Nov-Dec IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 366-73 CY - BRAZIL IP - 6 VI - 19 JC - S9D EM - 7809 PMID- 613432 SO - Rev Inst Med Trop Sao Paulo 1977 Nov-Dec;19(6):366-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 78099307 AU - Parnas J TI - Leptospirae: their place in the systematics. LA - Eng MH - Bacteria/cytology/physiology MH - Leptospira/*classification/cytology/physiology MH - Species Specificity PT - JOURNAL ARTICLE DA - 780329 DP - 1977 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 419-23 SB - M CY - GERMANY, WEST IP - 3 VI - 239 JC - Y52 AA - Author EM - 7805 AB - The morphology and electron-microscopic anatomy of Leptospirae, the lack of the presence of leptospiral phages (and probably of bacteriocins), and the absence of phagocytosis as a defence mechanism in leptospirosis, indicate the non-bacteriologie character of this genus. Leptospirae form an evolutionary intermediate bridge between the worlds of bacteria and protozoa. In "Bergey's Manual" they are assigned to the world of bacteria for practical reasons; but it seems to be reasonable to stress more largely the "bacteriological" and "protozoologic" markers of Leptospirae, in the subsequent 9th edition of this Manual. PMID- 602520 SO - Zentralbl Bakteriol [Orig A] 1977 Nov;239(3):419-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 78099303 AU - Cinco M TI - Factor analysis of serogroups botanica and aurisina of Leptospira biflexa. LA - Eng MH - Agglutination Tests MH - Antigens, Bacterial/analysis MH - Factor Analysis, Statistical MH - Leptospira/*classification MH - Serotyping PT - JOURNAL ARTICLE DA - 780329 DP - 1977 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 397-402 SB - M CY - GERMANY, WEST IP - 3 VI - 239 JC - Y52 AA - Author EM - 7805 AB - Factor analysis is performed on serovars of Botanica and Aurisina serogroup of Leptospira biflexa. The results show the arrangement of main factors serovar and serogroup specific, as well as the antigens common with serovars of heterologous serogroups. PMID- 602518 SO - Zentralbl Bakteriol [Orig A] 1977 Nov;239(3):397-402 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 78224274 AU - Ryan TJ AU - Marshall RB AU - Edwards JD AU - Stevenson BJ TI - Isolation of leptospires from the vitreous humor of aborted piglets [letter] LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Female MH - Fetus/microbiology MH - Leptospira/*isolation & purification MH - Pregnancy MH - Swine MH - Swine Diseases/*microbiology MH - Vitreous Body/*microbiology PT - LETTER DA - 780929 DP - 1977 Nov IS - 0048-0169 TA - N Z Vet J PG - 352 CY - NEW ZEALAND IP - 11 VI - 25 JC - OBZ EM - 7811 PMID- 276737 CU - 91 SO - N Z Vet J 1977 Nov;25(11):352 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 78146619 AU - Sramkova L AU - Vanista J AU - Polakova L AU - Cervova H AU - Klanica J TI - [Leptospiroses and their diagnostics (author's transl)] LA - Cze MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Child MH - Child, Preschool MH - Czechoslovakia MH - English Abstract MH - Female MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Sex Factors PT - JOURNAL ARTICLE DA - 780612 DP - 1977 Nov IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 363-9 CY - CZECHOSLOVAKIA IP - 6 VI - 26 JC - CSH EM - 7808 RO - M:LBR PMID- 147752 LR - 790213 CU - 92 TT - Leptospirozy a jejich diagnostika. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1977 Nov;26(6):363-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78099304 AU - Laber G AU - Schutze E TI - [In vitro and in vivo activity of tiamulin against leptospires (author's transl)] LA - Ger MH - Animal MH - Antibiotics/*pharmacology/therapeutic use MH - Comparative Study MH - Dihydrostreptomycin Sulfate/pharmacology MH - Disease Models, Animal MH - Diterpenes MH - Drug Screening MH - English Abstract MH - Female MH - Hamsters MH - Leptospira/*drug effects MH - Leptospirosis/drug therapy MH - Leucomycins/pharmacology MH - Male MH - Mesocricetus MH - Species Specificity MH - Tetracycline/pharmacology/therapeutic use PT - JOURNAL ARTICLE DA - 780329 DP - 1977 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 403-8 SB - M CY - GERMANY, WEST IP - 3 VI - 239 JC - Y52 AA - Author EM - 7805 AB - The minimal growth inhibiting concentration of tiamulin, a derivative of the diterpen antibiotic pleuromutilin, was evaluated in vitro against 11 different serogroups of leptospira interrogans by twofold serial dilution technique, in comparison to tetracyclin, dihydrostreptomycin and tylosin. The range of the MIC values of tiamulin is between 0.07 and 2.5 microgram/ml and thus comparable to the activities of the standard antibiotics tested (see table 1). The chemotherapeutic efficacy (ED50) of the compound was examined in two experimental leptospiral infections of the Syrian hamster, in comparison to tetracyclin. Both compounds were administered orally for 3 days. In the L. canicola infection, the ED50 values were 103.8 mg/kg and 306.3 mg/kg body-weight for tiamulin and tetracyclin, respectively. In the L. grippotyphosa infection, the ED50 values amounted to 35.16 and 277.5 mg/kg bodyweight for tiamulin and tetracyclin, respectively. Based on these values, tiamulin in comparison to tetracyclin showed 3-8 fold higher efficacy in vivo after oral administration. PMID- 74926 CU - 95 TT - Wirksamkeit von Tiamulin gegen Leptospiren in vitro und in vivo. EA - A SO - Zentralbl Bakteriol [Orig A] 1977 Nov;239(3):403-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 78050613 AU - Mochmann H AU - Meutery KP AU - Weihrauch TR AU - Kohler H AU - Gnandiger HP TI - [Fulminant course of a leptospira grippotyphosa infection (letter)] LA - Ger MH - Acute Disease MH - Adult MH - Female MH - Human MH - Leptospirosis/*diagnosis PT - LETTER DA - 780127 DP - 1977 Oct 28 IS - 0025-8458 TA - Med Klin PG - 1832-4 SB - M CY - GERMANY, WEST IP - 43 VI - 72 JC - M4E EM - 7803 PMID- 927288 CU - 91 TT - Foudroyanter Verlauf einer Infektion mit Leptospira grippotyphosa. SO - Med Klin 1977 Oct 28;72(43):1832-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 78057372 AU - Petrov EM AU - Chernukha YG TI - Potential variability of Leptospira serovars belonging to the same group. LA - Eng MH - Agglutination MH - Antigens, Bacterial/isolation & purification MH - Immune Sera MH - Leptospira/classification/*immunology/physiology MH - Mutation PT - JOURNAL ARTICLE DA - 780127 DP - 1977 Oct IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 252-61 SB - M CY - GERMANY, WEST IP - 2 VI - 239 JC - Y52 AA - Author EM - 7803 AB - 3 clone strains of monjakov and pomona serovars were cultured with prolongation in a medium containing homologous immune sera. Separate subcultures were cloned in a solid medium, while isolated clones were typed in microagglutination test with whole and absorbed immune sera and in some cases in an absorption test. The results showed that the mutants of subcultures with the minimal and maximal time of contact with the immune serum turned out to differ greatly from each other in antigenic properties. While antigenic mutants of earlier subcultures were constantly connected with serovars of Pomona serogroup, mutants of subcultures adapted to immune serum were serologically more related to butembo serovar of Cynoptery serogroup. The results obtained showing potential variability of serovars belonging to Pomona serogroup could be significant from the viewpoint of classification and phylogeny of Leptospira. PMID- 930476 SO - Zentralbl Bakteriol [Orig A] 1977 Oct;239(2):252-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 79035715 AU - Jelic S AU - Bojic P AU - Rosic D TI - [Microangiopathic hemolytic anemia with erythroblastosis in a patient with disseminated pancreatic carcinoma and leptospirosis] LA - Scc MH - Anemia, Hemolytic/*complications MH - Carcinoma/*complications MH - Case Report MH - Disseminated Intravascular Coagulation/complications MH - English Abstract MH - *Erythroblasts MH - *Erythrocytes MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Pancreatic Neoplasms/*complications PT - JOURNAL ARTICLE DA - 781220 DP - 1977 Oct IS - 0049-0210 TA - Srp Arh Celok Lek PG - 855-65 CY - YUGOSLAVIA IP - 10 VI - 105 JC - UZG EM - 7902 PMID- 616988 CU - 90 TT - Mikroangiopatska hemoliticka anemija sa eritroblastemijom u bolesnika sa diseminovanim karcinomom pankreasa i leptospirozom. EA - A SO - Srp Arh Celok Lek 1977 Oct;105(10):855-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 78180022 AU - Dimitriu S AU - Gavrila I TI - [Electrocardiographic changes in uncomplicated clinical leptospirosis. Comments on 73 cases] LA - Rum MH - Adolescence MH - Adult MH - Aged MH - Arrhythmia/*etiology MH - Electrocardiography MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Myocarditis/*etiology PT - JOURNAL ARTICLE DA - 780724 DP - 1977 Oct-Dec IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 561-5 CY - ROMANIA IP - 4 VI - 81 JC - SHP EM - 7809 PMID- 613399 TT - Modificari electrocardiografice in leptospiroza clinic necomplicata. Consideratii asupra 73 cazuri. EA - A SO - Rev Med Chir Soc Med Nat Iasi 1977 Oct-Dec;81(4):561-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 78165522 AU - Durfee PT AU - Presidents PJ TI - Isolation of Leptospira interrogans, serotype balcanica from a brush- tailed opossum (Trichosurus vulpecula) [letter] LA - Eng MH - Animal MH - Leptospira interrogans/*isolation & purification MH - Male MH - Opossums/*microbiology PT - LETTER DA - 780628 DP - 1977 Oct IS - 0005-0423 TA - Aust Vet J PG - 508 SB - M CY - AUSTRALIA IP - 10 VI - 53 JC - 9IE EM - 7808 PMID- 612328 CU - 91 SO - Aust Vet J 1977 Oct;53(10):508 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 78077102 AU - Tawfik MS AU - Hamed OM AU - El-Karamani R TI - Leptospirosis in Egyptian rodents. LA - Eng MH - Animal MH - Egypt MH - *Leptospirosis/diagnosis MH - Mice MH - Rats MH - *Rodent Diseases/diagnosis MH - Rodentia PT - JOURNAL ARTICLE DA - 780218 DP - 1977 Oct IS - 0514-7166 TA - Zentralbl Veterinarmed [B] PG - 728-32 CY - GERMANY, WEST IP - 9 VI - 24 JC - Y72 EM - 7804 PMID- 595978 CU - 84 SO - Zentralbl Veterinarmed [B] 1977 Oct;24(9):728-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 78200487 AU - Hodges RT AU - Weddell W TI - Adaptation of a complement fixation test for large scale serological diagnosis of bovine leptospirosis. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - *Complement Fixation Tests MH - Leptospirosis/diagnosis/*veterinary PT - JOURNAL ARTICLE DA - 780814 DP - 1977 Oct IS - 0048-0169 TA - N Z Vet J PG - 261-2 CY - NEW ZEALAND IP - 10 VI - 25 JC - OBZ EM - 7810 PMID- 275685 CU - 88 SO - N Z Vet J 1977 Oct;25(10):261-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78050842 AU - Clark CH TI - Clinical uses of kanamycin, neomycin and streptomycin. LA - Eng MH - Animal MH - Cat Diseases/drug therapy MH - Cats MH - Cattle MH - Cattle Diseases/drug therapy MH - Diarrhea/drug therapy/veterinary MH - Dihydrostreptomycin Sulfate/therapeutic use MH - Dog Diseases/drug therapy MH - Dogs MH - Escherichia coli Infections/drug therapy/veterinary MH - Kanamycin/*therapeutic use MH - Leptospirosis/drug therapy/veterinary MH - Neomycin/*therapeutic use MH - Salmonella Infections, Animal/drug therapy MH - Streptomycin/*therapeutic use MH - Swine MH - Swine Diseases/drug therapy PT - JOURNAL ARTICLE PT - REVIEW DA - 780127 DP - 1977 Oct IS - 0026-8542 TA - Mod Vet Pract PG - 845-50 SB - M CY - UNITED STATES IP - 10 VI - 58 JC - NGO EM - 7803 RF - 36 PMID- 73127 CU - 95 SO - Mod Vet Pract 1977 Oct;58(10):845-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 78056683 AU - Hergt R TI - [Leptospirosis due to bathing] LA - Ger MH - Adolescence MH - Adult MH - Case Report MH - Child MH - English Abstract MH - Female MH - Germany, East MH - Human MH - Leptospirosis/*etiology MH - Male MH - Middle Age MH - *Swimming MH - Water Microbiology PT - JOURNAL ARTICLE DA - 780127 DP - 1977 Sep IS - 0049-8610 TA - Z Gesamte Hyg PG - 668-9 CY - GERMANY, EAST IP - 9 VI - 23 JC - XUO EM - 7803 PMID- 930160 TT - Badeinfektionen durch Leptospiren. EA - A SO - Z Gesamte Hyg 1977 Sep;23(9):668-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 78038473 AU - Verma BB AU - Biberstein EL AU - Meyer ME TI - Serologic survey of leptospiral antibodies in horses in California. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - California MH - Horses/*immunology MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology PT - JOURNAL ARTICLE DA - 771229 DP - 1977 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1443-4 SB - M CY - UNITED STATES IP - 9 VI - 38 JC - 40C AA - Author EM - 7802 AB - A serologic survey was made of the prevalence of common leptospiral infections in horses in California. A total of 465 serums were tested, using the microscopic agglutination method, against 5 leptospiral serotypes: Leptospira pomona, Leptospira icterohaemorrhagiae, Leptospira canicola, Leptospira grippotyphosa, and Leptospira hardjo. Of the serums tested, 127 (27.30%) were positive against 1 or more of the leptospires, with percentage distribution among the reactors as follows: L pomona, 12.47%; L icterohaemorrhagiae, 10.32%; L canicola, 3.22%; L grippotyphosa, 0.86%; and L hardjo, 0.43%. The prevalence of reactors to leptospiral antigens did not differ with the age or sex of the animals. PMID- 921041 SO - Am J Vet Res 1977 Sep;38(9):1443-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78038467 AU - Nervig RM AU - Ellinghausen HC Jr AU - Cardella MA TI - Growth, virulence, and immunogenicity of Leptospira interrogans serotype szwajizak. LA - Eng MH - Animal MH - *Antibody Formation MH - Bacterial Vaccines/administration & dosage MH - Culture Media MH - Guinea Pigs MH - Hamsters MH - Leptospira interrogans/*growth & development/immunology MH - Leptospirosis/etiology/immunology MH - Male MH - Virulence PT - JOURNAL ARTICLE DA - 771229 DP - 1977 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1421-4 SB - M CY - UNITED STATES IP - 9 VI - 38 JC - 40C AA - Author EM - 7802 AB - Leptospira interrogans serotype szwajizak was characterized by (1) its growth in polysorbate 80-bovine albumin medium, (2) its virulence and course of infection in laboratory animals, and (3) its immunogenicity. Growth of this organism was continuous and vigorous at 29 C and 37 C in liquid medium for 10 serial subcultures. Some specific lots of agar were superior to other agars if tested for the ability to support the growth of small inoculums. Individual colonies resulted from growth of small inoculums on solid polysorbate medium. Virulence of the organisms did not appear to be altered by 10 serial subcultures in liquid medium incubated at 29 C. The estimated median lethal dose of szwajizak for hamsters by the intraperitoneal route was 2 cells. Virulence, infectivity, and pathogenicity of szwajizak were shown in the hamster and the guinea pig. Protection results indicate the heat-inactivated szwajizak bacterin was a substantially better immunizing agent than the chemically inactivated bacterin. Serotype hardjo bacterins provided hamsters some protection against death if challenge exposed with szwajizak, but afforded no protection against infection. PMID- 921038 SO - Am J Vet Res 1977 Sep;38(9):1421-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 78017890 AU - Thiermann AB TI - Incidence of leptospirosis in the detroit rat population. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Brain/microbiology MH - Kidney/microbiology MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Michigan MH - Rats/*microbiology MH - Rodent Diseases/*epidemiology/microbiology MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 771125 DP - 1977 Sep IS - 0002-9637 TA - Am J Trop Med Hyg PG - 970-4 SB - A SB - M CY - UNITED STATES IP - 5 Pt 1 VI - 26 JC - 3ZQ AA - Author EM - 7801 AB - The rat population (Rattus norvegicus) in the city of Detroit was surveyed to determine the incidence of leptospirosis. Four methods of survey were used--serological, direct examination of urine, culture of urine, kidney and brain, and histopathological examination. Of 358 sera tested by the microscopic-agglutination test, 277 (77.4%) had significant agglutinins for serotype icterohaemorrhagiae. Significant differences were found between adult and young animals in both incidence and antibody titers, titers of 1:50 or higher being present in 90.3% and 38.8%, respectively, of adult and young rats. Examination of freshly drawn urine by dark field microscopy revealed that 59.6% of the animals were shedding leptospirae. When stained with Steiner's silver stain, 91.9% of the kidney sections were positive for leptospirae, showing this to be the most sensitive test of those used. Leptospirae were isolated from one or more cultures of kidney, urine, or brain from 221 (59.2%) of the 358 rats examined. PMID- 907056 CU - 88 SO - Am J Trop Med Hyg 1977 Sep;26(5 Pt 1):970-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 78203319 AU - Cacchione RA AU - Cascelli ES AU - Saravi MA AU - Martinez ES TI - [Outbreak of leptospirosis in children at Longchamps, province of Buenos Aires, Argentina: laboratory diagnosis] LA - Spa MH - Argentina MH - Child MH - Disease Outbreaks MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology/immunology MH - Male PT - JOURNAL ARTICLE DA - 780828 DP - 1977 Sep-Dec IS - 0325-1713 TA - Rev Asoc Argent Microbiol PG - 126-8 SB - M CY - ARGENTINA IP - 3 VI - 9 JC - RCB EM - 7810 PMID- 614653 CU - 88 TT - "Brote de leptospirosis en ninos, de Longchamps, Pcia. de Buenos Aires, Argentina: diagnostico de laboratorio. EA - A SO - Rev Asoc Argent Microbiol 1977 Sep-Dec;9(3):126-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78113569 AU - Kucheruk VV AU - Olsuf'ev NG AU - Grokhovskaia IM AU - Karukin BE AU - Tarasevich IV AU - Chernukha IuG TI - [Study and prevention of natural-foci diseases in USSR] LA - Rus MH - Encephalitis, Tick-Borne/*prevention & control MH - English Abstract MH - Human MH - Leishmaniasis/*prevention & control MH - Leptospirosis/*prevention & control MH - Rickettsia Infections/*prevention & control MH - Tularemia/*prevention & control MH - USSR PT - JOURNAL ARTICLE DA - 780417 DP - 1977 Sep-Oct IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 537-45 CY - USSR IP - 5 VI - 46 JC - M72 EM - 7806 PMID- 580105 CU - 86 TT - Izuchenie i profilaktika prirodno-ochagovykh boleznei v SSSR. EA - A SO - Med Parazitol (Mosk) 1977 Sep-Oct;46(5):537-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [32 medline neighbors] UI - 77249374 AU - Greenberg EP AU - Canale-Parola E TI - Relationship between cell coiling and motility of spirochetes in viscous environments. LA - Eng MH - Culture Media MH - Escherichia coli/physiology MH - Leptospira/ultrastructure MH - Leptospira interrogans/*physiology MH - Movement MH - Mutation MH - Species Specificity MH - Spirillum/physiology MH - Spirochaeta/*physiology/ultrastructure MH - Support, U.S. Gov't, P.H.S. MH - Viscosity PT - JOURNAL ARTICLE DA - 771020 DP - 1977 Sep IS - 0021-9193 TA - J Bacteriol PG - 960-9 SB - M CY - UNITED STATES IP - 3 VI - 131 JC - HH3 AA - Author EM - 7712 AB - The lowest viscosity that stops translational motility of cells (minimum immobilizing viscosity [MIV] was determined for various spirochetes. The viscous agent used was polyvinylpyrrolidone, The MIV for either Spirochaeta halophila P1 or Spirochaeta aurantia J4T was approximately 1,000 centipoise (cp), and for Leptospira interrogans (biflexa) B16 the MIV was greater than 500 cp. In comparison, the MIV for the flagellated bacteria Escherichia coli and Spirillum serpens was 60 cp. MIV values for two S. halophila mutant strains lacking the characteristic cell coiling (Hel-mutants) were 70 and 120 cp, approximately one-tenth the MIV for the wild-type strain. MIV values for cells of S. aurantia strains with fewer coils than comparably long cells of S. aurantia J4T were 300 to 600 cp. The average velocity of strains of S. aurantia and S. halophila decreased at viscosities higher than 2 to 3 cp. At 2 cp the average velocity of S. halophila P1 was 16 micron/s, whereas the average velocities of Hel-mutant strains were 7 to 9 micron/s. This study indicates that the coiling of spirochetes plays a role in their ability to move through environments of realtively high viscosity. Among the spirochetes we investigated, this ability is greater in the more extensively coiled strains. PMID- 330506 CU - 90 SO - J Bacteriol 1977 Sep;131(3):960-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78146608 AU - Bazovska S TI - [Haemolysis of white rat erythrocytes by pathogenic and saprophytic strains of leptospires (author's transl)] LA - Slo MH - Animal MH - English Abstract MH - *Erythrocytes MH - Hemolysins/*analysis MH - Hemolysis MH - Leptospira/*pathogenicity MH - Phospholipids/blood MH - Rats PT - JOURNAL ARTICLE DA - 780617 DP - 1977 Sep IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 275-83 CY - CZECHOSLOVAKIA IP - 5 VI - 26 JC - CSH EM - 7808 RO - M:LBR PMID- 147743 LR - 790213 CU - 92 TT - Hemolyza potkanich erytrocytov patogennymi a saprofytarnymi kmenmi leptospir. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1977 Sep;26(5):275-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 78200532 AU - Millar KR AU - Hodges RT AU - Sheppard AD AU - Hammington MW TI - Clinical and biochemical changes in sheep inoculated with Leptospira interrogans serotype pomona. LA - Eng MH - Animal MH - Leptospirosis/metabolism/*veterinary MH - Sheep MH - Sheep Diseases/*metabolism PT - JOURNAL ARTICLE DA - 780814 DP - 1977 Aug IS - 0048-0169 TA - N Z Vet J PG - 203-7 CY - NEW ZEALAND IP - 8 VI - 25 JC - OBZ EM - 7810 PMID- 275721 CU - 88 SO - N Z Vet J 1977 Aug;25(8):203-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 77248485 AU - Adachi Y AU - Yanagawa R TI - Inhibition of leptospiral agglutination by the type-specific main antigens of leptospiras. LA - Eng MH - Agglutination Tests MH - *Antigens, Bacterial/analysis MH - Epitopes MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 771014 DP - 1977 Aug IS - 0019-9567 TA - Infect Immun PG - 466-7 SB - M CY - UNITED STATES IP - 2 VI - 17 JC - GO7 AA - Author EM - 7712 AB - Microscopic agglutination of leptospiras was inhibited by the homologous type-specific main antigens. The result may indicate that the substance participating in the agglutination of leptospiras with antiserum is the type-specific main antigen. PMID- 70411 CU - 95 SO - Infect Immun 1977 Aug;17(2):466-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 78093011 AU - Cameron GL TI - The susceptibility of New Zealand isolates of leptospira to three antibiotics. LA - Eng MH - Antibiotics/*pharmacology MH - Leptospira/*drug effects MH - Minocycline/pharmacology MH - New Zealand MH - Penicillin G/pharmacology MH - Penicillin Resistance MH - Tetracycline/pharmacology PT - JOURNAL ARTICLE DA - 780310 DP - 1977 Jul 27 IS - 0028-8446 TA - N Z Med J PG - 93-4 SB - M CY - NEW ZEALAND IP - 592 VI - 86 JC - OBQ AA - Author EM - 7805 AB - The susceptibilities of 14 recent isolates of Leptospira to benzyl penicillin, tetracycline and minocycline, were tested. All strains were highly susceptible to penicillin. The minimum inhibitory concentrations (MIC) of the two tetracyclines were generally low, and no significant difference was found between them. PMID- 271882 CU - 90 SO - N Z Med J 1977 Jul 27;86(592):93-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 78029223 AU - Maghami GH AU - Hooshmand-rad P AU - Farhang-azad A TI - Leptospirosis in small mammals of Iran: II: isolation of Leptospira grippotyphosa from Mus msuculus. LA - Eng MH - Animal MH - Iran MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Mice/*microbiology PT - JOURNAL ARTICLE DA - 771229 DP - 1977 Jul IS - 0090-3558 TA - J Wildl Dis PG - 286-9 SB - M CY - UNITED STATES IP - 3 VI - 13 JC - KEM AA - Author EM - 7802 AB - The serotype of Leptospira grippotyphosa, which is most frequently encountered among sheep, cattle and man in Iran, was isolated from the kidney of a house mouse, Mus musculus, by direct culture and animal inoculation. This is the first time that a rodent reservoir of L. grippotyphosa in Iran has been investigated and reported. PMID- 916143 SO - J Wildl Dis 1977 Jul;13(3):286-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 78001195 AU - Kmety E AU - Bakoss P AU - Manicova E AU - Stupalova S AU - Hrabinsky S AU - Peci J TI - [First observations of Leptospirosis sorex (author's transl)] LA - Slo MH - Acute Disease MH - Adolescence MH - Adult MH - Case Report MH - Czechoslovakia MH - English Abstract MH - Female MH - Human MH - Leptospira MH - Leptospirosis/*epidemiology MH - Male MH - Species Specificity PT - JOURNAL ARTICLE DA - 771125 DP - 1977 Jul IS - 0006-9248 TA - Bratisl Lek Listy PG - 37-41 CY - CZECHOSLOVAKIA IP - 1 VI - 68 JC - B5N EM - 7801 PMID- 902124 CU - 88 TT - Prve pozorovania leptospirozy sorex--jalna na Slovensku. EA - A SO - Bratisl Lek Listy 1977 Jul;68(1):37-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 77239900 AU - Arnold K AU - Kilbridge TM AU - Miller WC Jr AU - Smith TJ AU - Cutting RT TI - Mycoplasma pneumonia: a study on hospitalized American patients with pneumonia in Vietnam. LA - Eng MH - Adult MH - Female MH - Human MH - Male MH - Middle Age MH - Mycoplasma Infections/*complications/diagnosis/drug therapy/radiography MH - Pneumonia/diagnosis/drug therapy/*etiology/radiography MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 770922 DP - 1977 Jul IS - 0002-9637 TA - Am J Trop Med Hyg PG - 743-7 SB - A SB - M CY - UNITED STATES IP - 4 VI - 26 JC - 3ZQ AA - Author EM - 7711 AB - A prospective study on consecutively hospitalized pneumonia patients showed that 41.5% of 58 patients had a fourfold rise in the complement- fixation titer for Mycoplasma pneumoniae. Viral isolation techniques and serologic tests for influenza A1, A2 and B, parainfluenza 1 and 3, respiratory syncytial virus and the adeno virus group yielded only a single positive isolate for influenza A2. Serologic tests for melioidosis, leptospirosis, scrub, murine and epidemic typhus and psittacosis were all negative. The clinical manifestations were not distinctive for the positive M. pneumoniae patients when compared with the patients having a negative M. pneumoniae complement-fixation test. The symptoms and signs and laboratory and radiologic findings were similar to those described in other reports on primary atypical pneumonia. PMID- 889014 SO - Am J Trop Med Hyg 1977 Jul;26(4):743-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 77226908 AU - Adler B AU - Faine S TI - Host immunological mechanisms in the resistance of mice to leptospiral infections. LA - Eng MH - Animal MH - Antibodies, Bacterial MH - BCG Vaccine MH - Cortisone/pharmacology MH - Cyclophosphamide/pharmacology MH - Immunity MH - Immunosuppression MH - Leptospira/immunology MH - Leptospirosis/blood/*immunology MH - Mice MH - Mice, Inbred BALB C MH - Mice, Nude MH - Opsonins MH - Propionibacterium acnes PT - JOURNAL ARTICLE DA - 770929 DP - 1977 Jul IS - 0019-9567 TA - Infect Immun PG - 67-72 SB - M CY - UNITED STATES IP - 1 VI - 17 JC - GO7 AA - Author EM - 7711 AB - Several serovars of Leptospira virulent for hamsters and guinea pigs caused acute lethal leptospirosis in mice immunosuppressed with cyclophosphamide. Neither BCG vaccine nor Corynebacterium parvum suspension influenced the course of leptospiral infection in either immunosuppressed or normal BALB/c mice. Nude athymic mice produced anti- leptospiral antibody and were therefore resistant to infection with leptospires. Nude mice were made susceptible with cyclophosphamide but were immune if they had acquired antibody from previous infection or immunization. The evidence suggests that mechanisms of resistance to primary infection and immunity to reinfection are exclusively humorally mediated in mice. The roles of host and microbial factors in the outcome of infection are discussed. PMID- 885617 CU - 90 SO - Infect Immun 1977 Jul;17(1):67-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 78074500 AU - Bercovici C AU - Straton A AU - Straton C AU - Beldiman N AU - Stefanescu E AU - Anton N AU - Tudor G AU - Vrabie S AU - Catineanu A TI - [Study of the natural reservoir of Leptospira in the Danube Delta. II. Area of the Sulina branch] LA - Rum MH - Animal MH - Antibodies, Bacterial/isolation & purification MH - *Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology MH - Rodentia/*microbiology MH - Romania PT - JOURNAL ARTICLE DA - 780218 DP - 1977 Jul-Sep IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 421-4 CY - ROMANIA IP - 3 VI - 81 JC - SHP EM - 7804 PMID- 563612 CU - 88 TT - Studiul rezervorului natural de leptospire din Delta Dunarii. Nota II. Zona bratului Sulina. EA - A SO - Rev Med Chir Soc Med Nat Iasi 1977 Jul-Sep;81(3):421-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 78255769 AU - Bianchi L TI - [Blood culture in the leptospiroses (author's transl)] LA - Ita MH - *Bacteriological Techniques MH - Blood/*microbiology MH - Comparative Study MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis/microbiology MH - Serodiagnosis/methods PT - JOURNAL ARTICLE DA - 781025 DP - 1977 Jul-Aug IS - 0003-472X TA - Ann Sclavo PG - 886-91 CY - ITALY IP - 4 VI - 19 JC - 65C AA - Author EM - 7812 AB - In the early stage of Leptospirae infection there is always blood stream invasion so blood culture is the best diagnostic test and permit precise etiologic identification. In the paper methods and selective media are suggested and the possibility of mistake so called "pseudo Spirochaetes" for Leptospirae is emphasized. Personal experience about the streght of blood culture in comparison with Martin and Pettit serumdiagnostic tests is reported. RO - M:MYA PMID- 356779 LR - 821220 CU - 90 TT - La emocoltura nelle leptospirosi. EA - A SO - Ann Sclavo 1977 Jul-Aug;19(4):886-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 78001197 AU - Vosta J AU - Hanak P AU - Vychodil J TI - [Effect of population dynamics of small mammals on spread and survival of Leptospira grippotyphosa in foci (author's transl)] LA - Cze MH - Animal MH - Czechoslovakia MH - English Abstract MH - Leptospira/*physiology MH - Mice MH - Microtinae MH - *Population Dynamics MH - Rodentia/*microbiology PT - JOURNAL ARTICLE DA - 771125 DP - 1977 Jul IS - 0006-9248 TA - Bratisl Lek Listy PG - 50-6 CY - CZECHOSLOVAKIA IP - 1 VI - 68 JC - B5N EM - 7801 PMID- 332276 CU - 90 TT - Vliv populacni dynamiky drobnych savcu na sireni a prezivani Leptospira grippotyphosa v ohnisku. EA - A SO - Bratisl Lek Listy 1977 Jul;68(1):50-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 77241956 AU - Myers DM AU - Cuba Caparo A AU - Payan Moreno J TI - [Isolation of the serotype hardjo and other Leptospiraes from armadillos in Argentina] LA - Spa MH - Animal MH - Argentina MH - *Armadillos MH - Disease Reservoirs MH - *Edentata MH - English Abstract MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/*microbiology MH - Rodent Diseases/microbiology MH - Serotyping PT - JOURNAL ARTICLE DA - 771020 DP - 1977 Jul IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 56-65 CY - UNITED STATES IP - 1 VI - 83 JC - AGG EM - 7712 PMID- 142490 CU - 92 TT - Aislamiento del serotipo hardjo y otras leptospiras de armadillos de Argentina. EA - A SO - Bol Oficina Sanit Panam 1977 Jul;83(1):56-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 77237386 AU - Wilson JH AU - Hermann-Dekkers WM AU - Leemans-Dessy S AU - Meijer JW TI - Experiements with an inactivated hepatitis leptospirosis vaccine in vaccination programmes for dogs. LA - Eng MH - Adenoviruses, Canine/*immunology MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/analysis MH - *Bacterial Vaccines MH - Distemper/prevention & control MH - Distemper Virus, Canine/immunology MH - Dog Diseases/*prevention & control MH - Dogs MH - Hepatitis, Infectious Canine/*prevention & control MH - Immunity, Maternally-Acquired MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/prevention & control/*veterinary MH - Measles Vaccine MH - Vaccination/*veterinary MH - *Viral Vaccines PT - JOURNAL ARTICLE DA - 770922 DP - 1977 Jun 25 IS - 0042-4900 TA - Vet Rec PG - 552-4 SB - M CY - ENGLAND IP - 26 VI - 100 JC - XBS AA - Author EM - 7711 AB - A fluid adjuvanted vaccine consisting of inactivated hepatitis virus (iH) and leptospirae antigens (L) was developed. The vaccine (Kavak iHL; Duphar) was tested in several vaccination programmes both alone and in combination with freeze dried measles (M) or distemper (D) vaccines. The results demonstrate that this new vaccine is also effective in pups with maternally derived antibodies, although a second vaccination at 14 weeks of age is recommended to boost the first vaccination. For the booster vaccination either the iHL-vaccine or the liver attenuated hepatitis vaccine (H) can be used. PMID- 196386 CU - 93 SO - Vet Rec 1977 Jun 25;100(26):552-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 77217468 AU - Maclaren AP AU - Wright CL AU - Guthrie M TI - Leptospirosis in cattle in south west Scotland [letter] LA - Eng MH - Animal MH - Cattle MH - *Cattle Diseases MH - Leptospirosis/*veterinary MH - Scotland PT - LETTER DA - 770825 DP - 1977 Jun 18 IS - 0042-4900 TA - Vet Rec PG - 535-6 SB - M CY - ENGLAND IP - 25 VI - 100 JC - XBS EM - 7710 PMID- 878275 CU - 91 SO - Vet Rec 1977 Jun 18;100(25):535-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 78014612 AU - De Geus A AU - Oomen LJ TI - Medical research in Kenya. IV. Tropical medicine and pathology. LA - Eng MH - Adult MH - Aged MH - Brucellosis/epidemiology MH - Female MH - Hepatomegaly/epidemiology MH - Human MH - Infant MH - Infant Mortality MH - Infant, Newborn MH - Kenya MH - Leptospirosis/epidemiology MH - Lumbosacral Region MH - Male MH - *Morbidity MH - Myocarditis/epidemiology/etiology MH - Spinal Diseases/epidemiology MH - Splenomegaly/epidemiology MH - Tropical Medicine MH - Trypanosomiasis/complications/epidemiology PT - JOURNAL ARTICLE DA - 771125 DP - 1977 Jun IS - 0041-3232 TA - Trop Geogr Med PG - S31-5 SB - M CY - NETHERLANDS IP - 2 VI - 29 JC - WGJ EM - 7801 PMID- 906069 CU - 88 SO - Trop Geogr Med 1977 Jun;29(2):S31-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 77262191 AU - Eshov GI TI - [Fatty acid and lipid content of leptospirae] LA - Rus MH - Fatty Acids/analysis MH - Leptospira/*analysis MH - Lipids/*analysis MH - Phospholipids/analysis PT - JOURNAL ARTICLE DA - 771014 DP - 1977 Jun IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 127-9 SB - M CY - USSR IP - 6 JC - Y9O EM - 7712 PMID- 899427 TT - Soderzhanie lipidov i zhirnykh kislot u leptospir. SO - Zh Mikrobiol Epidemiol Immunobiol 1977 Jun;(6):127-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 77251465 AU - Palit A AU - Harrison PM TI - Immunochemistry of extracts from Leptospira interrogans serotype hardjo. LA - Eng MH - Antigens, Bacterial/*analysis MH - Bacterial Proteins/analysis MH - Carbohydrates/analysis MH - Hemagglutination Tests MH - Leptospira interrogans/*immunology/ultrastructure MH - Serotyping PT - JOURNAL ARTICLE DA - 771020 DP - 1977 Jun IS - 0022-1287 TA - J Gen Microbiol PG - 249-56 SB - M CY - ENGLAND IP - 2 VI - 100 JC - I87 AA - Author EM - 7712 AB - Antigens from Leptospira interrogans serotype hardjo grown in modified Korthof's medium were obtained by ethanol and alkaline extraction procedures and their chemical and serological properties were compared. The protein to polysaccharide ratio in the ethanol extract was 1:1-8 and in the alkali extract was 1-7:1. The lipid content of the latter was twice that of the former (8-5%, w/w). There was an inverse relationship of the protein and carbohydrate contents of the two preparations, the total reducing sugar being higher in the ethanol extract whereas protein was higher in the alkali extract. Both preparations contained arabinose, rhamnose, fucose, xylose, mannose, galactose, glucose and galacturonic acid but in different amounts. No muramic acid or 2-keto-3-deoxyoctonate was detected. Both extracts contained erythrocyte sensitizing substances which, in the passive haemagglutination absorption test, appeared to be closely related antigenically but not identical. In the electron microscope, thin sections of the ethanol extract showed trilaminar outer envelope-like material. PMID- 894262 SO - J Gen Microbiol 1977 Jun;100(2):249-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 77227096 AU - Kitaoka M AU - Duong-Hong-Mo AU - Mori M TI - Identification of Leptospira strains isolated from rats in Saigon as Leptospira bataviae or its subserotype. LA - Eng MH - Animal MH - Leptospira/immunology/*isolation & purification MH - Rats/*microbiology MH - Vietnam PT - JOURNAL ARTICLE DA - 770922 DP - 1977 Jun TA - Int J Zoonoses PG - 45-7 SB - M CY - TAIWAN IP - 1 VI - 4 JC - GTK EM - 7711 PMID- 885672 CU - 89 SO - Int J Zoonoses 1977 Jun;4(1):45-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 77227095 AU - Farina R AU - Andreani E AU - Tolari F TI - Leptospirosis in swine--experimental infection with serotype bratislava. LA - Eng MH - Abortion, Veterinary/etiology MH - Animal MH - Female MH - Kidney/pathology MH - Leptospirosis/etiology/pathology/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*etiology/pathology PT - JOURNAL ARTICLE DA - 770922 DP - 1977 Jun TA - Int J Zoonoses PG - 38-44 SB - M CY - TAIWAN IP - 1 VI - 4 JC - GTK EM - 7711 PMID- 885671 CU - 89 SO - Int J Zoonoses 1977 Jun;4(1):38-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 78046883 AU - Kobayashi Y TI - [Leptospirosis and Weil's disease] LA - Jpn MH - Human MH - Leptospirosis/*diagnosis/drug therapy MH - Streptomycin/therapeutic use MH - Weil's Disease/*diagnosis/drug therapy PT - JOURNAL ARTICLE DA - 780127 DP - 1977 Jun IS - 0387-5911 TA - Kansenshogaku Zasshi PG - 261-263 CY - JAPAN IP - 6 VI - 51 JC - IJR EM - 7803 PMID- 411838 CU - 91 SO - Kansenshogaku Zasshi 1977 Jun;51(6):261-263 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 77230643 AU - Craun GF TI - Waterborne outbreaks. LA - Eng MH - Amebiasis/transmission MH - Animal MH - Cholera/transmission MH - Dermatitis/etiology/transmission MH - *Disease Outbreaks MH - Dysentery, Bacillary/transmission MH - Escherichia coli Infections/transmission MH - Gastroenteritis/etiology/transmission MH - Giardiasis/transmission MH - Human MH - Leptospirosis/transmission MH - Meningoencephalitis/etiology/transmission MH - Mycobacterium Infections/transmission MH - Pseudomonas Infections/transmission MH - Salmonella Infections/transmission MH - Schistosomiasis/transmission MH - Shellfish/poisoning MH - Tularemia/transmission MH - Typhoid/transmission MH - Vibrio parahaemolyticus MH - Vibrio Infections/transmission MH - *Water Microbiology MH - Yersinia Infections/transmission PT - JOURNAL ARTICLE PT - REVIEW DA - 770922 DP - 1977 Jun IS - 0043-1303 TA - J Water Pollut Control Fed PG - 1268-79 CY - UNITED STATES IP - 6 VI - 49 JC - KDZ EM - 7711 RF - 74 PMID- 328941 CU - 90 SO - J Water Pollut Control Fed 1977 Jun;49(6):1268-79 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 77227091 AU - Steele JH TI - The zoonoses in the South Pacific and their public health significance. LA - Eng MH - Animal MH - Animal Husbandry MH - Cattle MH - Cattle Diseases/epidemiology MH - Cestode Infections/veterinary MH - Dirofilariasis/veterinary MH - Dog Diseases/epidemiology MH - Dogs MH - Escherichia coli Infections/veterinary MH - Fiji MH - Food Handling MH - Goats MH - Human MH - Leptospirosis/veterinary MH - Mycoses/veterinary MH - *Public Health MH - Screw Worm Infection/veterinary MH - Tuberculosis, Bovine/epidemiology MH - Western Samoa MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 770922 DP - 1977 Jun TA - Int J Zoonoses PG - 1-20 SB - M CY - TAIWAN IP - 1 VI - 4 JC - GTK EM - 7711 PMID- 328423 CU - 90 SO - Int J Zoonoses 1977 Jun;4(1):1-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 77266325 AU - Gordon LM TI - Leptospira interrogans serotype hardjo outbreak in a Victorian dairy herd and associated infection in man. LA - Eng MH - Agglutinins/analysis MH - Animal MH - Case Report MH - Cattle MH - Cattle Diseases/immunology/*microbiology MH - Disease Outbreaks/*veterinary MH - Guinea Pigs MH - Human MH - Leptospira interrogans/immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - Male MH - Milk/microbiology MH - Urine/microbiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 771014 DP - 1977 May IS - 0005-0423 TA - Aust Vet J PG - 227-9 SB - M CY - AUSTRALIA IP - 5 VI - 53 JC - 9IE AA - Author EM - 7712 AB - Leptospirosis associated with probable L. hardjo infection was investigated in a dairy herd in a coastal district of Western Victoria. Thirty-six of 110 cows suffered leptospiruria and mastitis characterised by flaccid udders and abnormal milk. One of two media used enabled the isolation of the organism from infected guinea pigs inoculated with fresh urine. Microscopic agglutination titres to L. hardjo were elevated during the outbreak. There was an associated human infection. PMID- 901323 SO - Aust Vet J 1977 May;53(5):227-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 77262097 AU - Kida H AU - Ishii T AU - Tsunehisa Y AU - Yamamoto S AU - Yanagawa R TI - Comparison of vaccines prepared from leptospires grown in a serum medium and in a chemically defined medium. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Comparative Study MH - Culture Media MH - Genetics, Microbial MH - Guinea Pigs MH - Leptospira/growth & development/*immunology MH - Mutation MH - Rabbits/immunology PT - JOURNAL ARTICLE DA - 771020 DP - 1977 May IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 86-96 SB - M CY - GERMANY, WEST IP - 1 VI - 238 JC - Y52 AA - Author EM - 7712 AB - Two types of leptospiral vaccines consisting of the organisms of four strains (strain Shibaura of Icterohaemorrhagiae serogroup, strain Akiyami A of serotype autumnalis, strain Akiyami B of serotype hebdomadis and strain Akiyami C of serotype australis) were prepared; one type was prepared from these strains grown in KORTHOF'S medium containing normal rabbit serum (the serum medium vaccine), and the other was made from mutants grown in SHENBERG'S chemically defined medium (the chemically defined medium vaccine). The protein nitrogen was lower and electron microscopical impurities were fewer in the chemically defined medium vaccine than in the serum medium vaccine. The rabbit serum was detected by the precipitation test in the serum medium vaccine. The results of the potency test did not differ between the two vaccines. The decrease in body weight of animals one day after intraperitoneal injection was induced equally by both vaccines. These results indicate that the chemically defined medium vaccine is preferable to the serum medium vaccine. PMID- 899375 SO - Zentralbl Bakteriol [Orig A] 1977 May;238(1):86-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 77206693 AU - Shrader WA Jr TI - Leptospirosis in Hawaii. LA - Eng MH - Hawaii MH - Human MH - *Leptospirosis/immunology/transmission PT - JOURNAL ARTICLE DA - 770812 DP - 1977 May IS - 0017-8594 TA - Hawaii Med J PG - 135-8 CY - UNITED STATES IP - 5 VI - 36 JC - G1D EM - 7710 PMID- 873785 SO - Hawaii Med J 1977 May;36(5):135-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77200647 AU - Buckler JM TI - Leptospirosis presenting with erythema nodosum. LA - Eng MH - Bradycardia/etiology MH - Case Report MH - Child MH - Erythema Nodosum/*etiology MH - Human MH - Leptospirosis/complications/*diagnosis MH - Male MH - Meningitis/etiology PT - JOURNAL ARTICLE DA - 770723 DP - 1977 May IS - 0003-9888 TA - Arch Dis Child PG - 418-9 SB - M CY - ENGLAND IP - 5 VI - 52 JC - 6XG AA - Author EM - 7709 AB - An illness due to a leptospiral infection in a boy aged 12 years is described which, in addition to presenting with severe fever, malaise, and aseptic meningitis, showed the rare features of severe bradycardia and erythema nodosum. PMID- 869574 SO - Arch Dis Child 1977 May;52(5):418-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 77206900 AU - Hanson LE TI - Immunology of bacterial diseases, with special reference to leptospirosis. LA - Eng MH - Abortion, Veterinary/etiology MH - Agglutinins/analysis MH - Animal MH - Bacterial Infections/immunology/*veterinary MH - Cattle MH - Cattle Diseases/*immunology MH - Female MH - IgG/analysis MH - IgM/analysis MH - Immunization MH - Infertility, Female/etiology/veterinary MH - Leptospirosis/complications/immunology/physiopathology/*veterinary MH - Male MH - Pregnancy MH - Time Factors MH - Vaccination/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 770812 DP - 1977 May 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 991-4 SB - M CY - UNITED STATES IP - 9 VI - 170 JC - HAV EM - 7710 RF - 46 PMID- 326741 CU - 90 SO - J Am Vet Med Assoc 1977 May 1;170(9):991-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 77192040 TI - Preconditioning feedlot calves. LA - Eng MH - Animal MH - Animal Feed MH - Bovine Virus Diarrhea-Mucosal Disease/prevention & control MH - Cattle MH - Cattle Diseases/*prevention & control MH - Infectious Bovine Rhinotracheitis/prevention & control MH - Leptospirosis/prevention & control/veterinary MH - Pasteurellosis, Pneumonic/prevention & control MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 770718 DP - 1977 May IS - 0026-8542 TA - Mod Vet Pract PG - 471-3 SB - M CY - UNITED STATES IP - 5 VI - 58 JC - NGO EM - 7709 PMID- 325359 CU - 90 NI - A SO - Mod Vet Pract 1977 May;58(5):471-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 78200511 AU - Millar KR AU - Hodges RT AU - Hammington MW TI - The effect of Leptospira interrogans serotype pomona infection on some characteristics of pig urine. LA - Eng MH - Animal MH - Leptospira interrogans MH - Leptospirosis/urine/*veterinary MH - Swine MH - Swine Diseases/*urine PT - JOURNAL ARTICLE DA - 780814 DP - 1977 May IS - 0048-0169 TA - N Z Vet J PG - 115-7 CY - NEW ZEALAND IP - 5 VI - 25 JC - OBZ EM - 7810 PMID- 275705 CU - 88 SO - N Z Vet J 1977 May;25(5):115-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 77192131 AU - Mayr A TI - [Vaccinations of animals and human health (author's transl)] LA - Ger MH - Animal MH - Cats MH - Cattle MH - Communicable Disease Control MH - Communicable Diseases/transmission MH - Dogs MH - English Abstract MH - Human MH - Rabies/prevention & control MH - Rabies Vaccine/adverse effects MH - Reoviridae Infections/prevention & control MH - Salmonella Infections/prevention & control MH - Salmonella Infections, Animal/prevention & control MH - *Vaccination/adverse effects/veterinary MH - Vaccinia/prevention & control PT - JOURNAL ARTICLE DA - 770723 DP - 1977 Apr 22 IS - 0341-3098 TA - MMW Munch Med Wochenschr PG - 551-4 SB - M CY - GERMANY, WEST IP - 16 VI - 119 JC - NMM AA - Author EM - 7709 AB - Vaccination of animals may have both positive and negative effects on human health. The negative consequences largely occur with live vaccines. The protection provided by vaccination to animals is taken advantage of for human health in the most diverse ways, both directly and indirectly. Typical examples are vaccination of dogs and cats against against rabies and inoculation against diseases of cattle, horses and dogs in which reoviruses of serotypes 1, 2 and 3 are involved. An important contribution to the protection of human health is also provided by vaccination with inactivated pathogens against leptospirosis and salmonellosis, against stomatitis vesicularis and American equine encephalitis and in developing countries against brucellosis. PMID- 194146 CU - 93 TT - Schutzimpfung beim Tier und menschliche Gesundheit EA - A SO - MMW Munch Med Wochenschr 1977 Apr 22;119(16):551-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [215 medline neighbors] UI - 77172593 AU - McQuillan WJ TI - Leptospirosis. LA - Eng MH - Human MH - *Leptospirosis PT - JOURNAL ARTICLE DA - 770611 DP - 1977 Apr 14 IS - 0029-6589 TA - Nurs Times PG - 535-6 CY - ENGLAND IP - 15 VI - 73 JC - O9U EM - 7708 PMID- 854448 SO - Nurs Times 1977 Apr 14;73(15):535-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 78013433 AU - Straton C AU - Bercovici C AU - Straton A AU - Beldiman N AU - Stefanescu E AU - Anton N AU - Tudor G AU - Vrabie S AU - Catineanu A TI - [Study of the natural reservoir of Leptospira in the Danube delta. I. Chilia branch region] LA - Rum MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - *Disease Reservoirs MH - English Abstract MH - Leptospirosis/*epidemiology MH - Rats MH - Rodent Diseases/*epidemiology MH - Romania MH - Sheep MH - Swine PT - JOURNAL ARTICLE DA - 771125 DP - 1977 Apr-Jun IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 233-7 CY - ROMANIA IP - 2 VI - 81 JC - SHP EM - 7801 PMID- 905681 CU - 88 TT - Studiul rezervorului natural de leptospire din delta dunarii. Nota i. Zona bratului chilia. EA - A SO - Rev Med Chir Soc Med Nat Iasi 1977 Apr-Jun;81(2):233-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 77258306 AU - Zavala-Velazquez J AU - Herrera-Hoys J AU - Laviada FA TI - [Human leptospirosis in the state of Yucatan (author's transl)] LA - Spa MH - Adolescence MH - Adult MH - Blood Transfusion MH - Case Report MH - English Abstract MH - Human MH - Leptospira/isolation & purification MH - *Leptospirosis/drug therapy/microbiology MH - Male MH - Mexico MH - Penicillins/therapeutic use PT - JOURNAL ARTICLE DA - 771028 DP - 1977 Apr-Jun IS - 0034-8376 TA - Rev Invest Clin PG - 161-4 CY - MEXICO IP - 2 VI - 29 JC - SCH EM - 7712 PMID- 897391 TT - Leptospirosis humana en el estado de Yucatan. EA - A SO - Rev Invest Clin 1977 Apr-Jun;29(2):161-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 77206640 AU - Shenberg E AU - Bitnun S AU - Birnbaum SH TI - Leptospirosis among dairy workers in the valley of Jezreel: first recorded isolation of Leptospira hardjo in Israel. LA - Eng MH - Animal MH - Cattle MH - Cross Reactions MH - *Dairying MH - Diagnosis, Differential MH - Female MH - Hedgehogs MH - Human MH - Israel MH - Leptospira/immunology MH - Leptospirosis/*epidemiology/immunology/transmission MH - Male MH - Occupational Diseases/*epidemiology/immunology/transmission MH - Rats MH - Serotyping MH - Zoonoses PT - JOURNAL ARTICLE DA - 770812 DP - 1977 Apr IS - 0021-2180 TA - Isr J Med Sci PG - 377-84 SB - M CY - ISRAEL IP - 4 VI - 13 JC - GY0 AA - Author EM - 7710 AB - Five cases of leptospirosis among dairy farmers in the Valley of Jezreel are described. The disease was caused by leptospirae of serotype hardjo and available epidemiological evidence suggested infection due to contact with cows. This is the first time that Leptospira hardjo has been isolated and identified in Israel. Infection with L. hardjo should be regarded as a significant occupational risk and this strain should be included in the group of antigens used for screening sera for leptospira antibodies in Israel. PMID- 873758 CU - 88 SO - Isr J Med Sci 1977 Apr;13(4):377-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 77190374 AU - Smith AW AU - Brown RJ AU - Skilling DE AU - Bray HL AU - Keyes MC TI - Naturally-occurring leptospirosis in northern fur seals (Callorhinus ursinus). LA - Eng MH - Animal MH - Kidney/microbiology/pathology MH - Leptospira/isolation & purification MH - Leptospirosis/microbiology/pathology/*veterinary MH - Liver/microbiology/pathology MH - *Pinnipedia MH - *Seals MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 770718 DP - 1977 Apr IS - 0090-3558 TA - J Wildl Dis PG - 144-8 SB - M CY - UNITED STATES IP - 2 VI - 13 JC - KEM AA - Author EM - 7709 AB - A 4-year study of Northern fur seal (Callorhinus ursinus) leptospirosis in the Bering Sea has shown that in newborn pups Leptospira pomona is associated with a multiple hemorrhage syndrome. Adults may develop an interstitial nephritis and shed organisms in the urine. The hed prevalence, based on microscopic slide agglutination tests, ranged between 7.0% and 15.4% for adult females and 3-4 year old bachelor bulls, whereas nursing pups averaging 4 months of age had a prevalence of 2%. These results are used to conclude that leptospirosis is not acquired primarily on the breeding rookeries but rather is more frequently acquired subsequent to the purps leaving the rookeries, presumably through the food chain during their first pelagic cycle. PMID- 864847 CU - 90 SO - J Wildl Dis 1977 Apr;13(2):144-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 77183233 AU - Higgin R AU - Cousineau G TI - The pathogenisis of leptospirosis II. Jaundice in experimental leptospirosis in guinea pigs. LA - Eng MH - Animal MH - Fever/veterinary MH - Gallbladder/pathology MH - *Guinea Pigs MH - Jaundice/blood/pathology/*veterinary MH - Leptospira interrogans MH - Leptospirosis/blood/pathology/*veterinary MH - Liver/pathology MH - Reticuloendothelial System/radiation effects MH - *Rodent Diseases/blood/pathology PT - JOURNAL ARTICLE DA - 770718 DP - 1977 Apr IS - 0008-4050 TA - Can J Comp Med PG - 182-7 SB - M CY - CANADA IP - 2 VI - 41 JC - CI0 AA - Author EM - 7709 AB - Different mechanisms responsible for the appearance of jaundice in leptospirosis caused by Leptospira icterohaemorrhagiae in guinea pigs were discussed. Hepatocellular damage was demonstrated with the presence to a lesser extent of intrahepatic biliary obstruction. A massive destruction of extravascular red blood cells liberated by the hemorrhagic diathesis, appeared to be the main cause in the genesis of jaundice. The latter was inhibited following the neutralization of the reticuloendothelial system of guinea pigs by an irradiation before the infection. PMID- 861836 SO - Can J Comp Med 1977 Apr;41(2):182-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 77183232 AU - Higgins R AU - Cousineau G TI - The pathogenesis of leptospirosis I. Hemorrhages in experimental leptospirosis in guinea pigs. LA - Eng MH - Animal MH - Factor V/analysis MH - Factor VIII/analysis MH - Fibrinogen/analysis MH - *Guinea Pigs MH - Hemorrhage/blood/*veterinary MH - Leptospira interrogans MH - Leptospirosis/blood/pathology/*veterinary MH - Liver/pathology MH - Lung/pathology MH - Male MH - *Rodent Diseases/blood/pathology PT - JOURNAL ARTICLE DA - 770718 DP - 1977 Apr IS - 0008-4050 TA - Can J Comp Med PG - 174-81 SB - M CY - CANADA IP - 2 VI - 41 JC - CI0 AA - Author EM - 7709 AB - In experimental infections of guinea pigs with a virulent strain of Leptospira icterohaemorrhagiae widespread hemorrhages were observed. Thrombocytopenia, prolongation of prothrombin, thrombin, partial thromboplastin and coagulation times, decrease of plasma fibrinogen, factor V, factor VIII and the presence of fibrinogen degradation products were demonstrated. Treatment of infected guinea pigs with heparin prolonged life for two to three days. The histological observations revealed that the main lesion is a severe injury of the vasculature, mainly arteries, arterioles and capillaries. Most of the endothelial cells are affected or destroyed and the muscular fibers of arteries and arterioles are injured. With Martius-Scarlet-Blue, Weigert or Picro-Mallory stains it was demonstrated that the organization seen in the vessels is not all made of fibrin. The conclusion reached was that the hemorrhages observed in experimental leptospirosis in guines pigs are due to disseminated intravascular coagulation. PMID- 861835 SO - Can J Comp Med 1977 Apr;41(2):174-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 77176885 AU - Duka TV AU - Zeigermakher GA AU - Ponomarenko GF AU - Ievleva TN TI - [Sporadic incidence of leptospirosis in Zaporozh'e] LA - Rus MH - Adult MH - Case Report MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - USSR PT - JOURNAL ARTICLE DA - 770630 DP - 1977 Apr IS - 0049-6804 TA - Vrach Delo PG - 138-9 CY - USSR IP - 4 JC - XLS EM - 7708 PMID- 860489 CU - 88 TT - O sporadicheskikh zabolevaniiakh leptospirozami v Zaporozh'e SO - Vrach Delo 1977 Apr;(4):138-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 78234643 AU - Nicolescu M TI - Increase in sensitivity of the Patoc antigen as used in the diagnosis of human leptospirosis by the complement fixation test. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial/*analysis MH - Comparative Study MH - Complement Fixation Tests MH - Human MH - Immune Sera/analysis MH - Leptospira/*immunology MH - Rabbits/immunology MH - Sheep/immunology PT - JOURNAL ARTICLE DA - 780925 DP - 1977 Apr-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 145-50 CY - ROMANIA IP - 2 VI - 36 JC - 8EM EM - 7811 PMID- 615569 SO - Arch Roum Pathol Exp Microbiol 1977 Apr-Jun;36(2):145-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 77120668 AU - Wong ML AU - Kaplan S AU - Dunkle LM AU - Stechenberg BW AU - Feigin RD TI - Leptospirosis: a childhood disease LA - Eng MH - Adolescence MH - Animal MH - Case Report MH - Child MH - Child, Preschool MH - Disease Vectors MH - Dogs MH - Female MH - Human MH - Leptospira/immunology/isolation & purification MH - Leptospira interrogans/immunology/isolation & purification MH - *Leptospirosis/diagnosis/epidemiology MH - Male MH - Missouri MH - *Weil's Disease/diagnosis/epidemiology PT - JOURNAL ARTICLE DA - 770430 DP - 1977 Apr IS - 0022-3476 TA - J Pediatr PG - 532-7 SB - A SB - M CY - UNITED STATES IP - 4 VI - 90 JC - JLZ AA - Author EM - 7706 AB - A diagnosis of leptospirosis was confirmed in nine children who were admitted to St. Louis Children's Hospital during the past 54 months. Epidemiologic, clinical, cultural, and serologic data which were obtained emphasize (1) the high incidence of urban cases; (2) contact with dogs as the most likely source of infection; and (3) that serotypes other than Leptospira icterohaemorrhagiae may produce severe clinical disease. Unusual or previously unreported manifestations of leptospirosis including acalculous cholecystitis, pancreatitis, abdominal causalgia, desquamating skin rashes, and infarction of the extremities which were noted in these children are discussed. PMID- 557083 CU - 88 SO - J Pediatr 1977 Apr;90(4):532-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 78234644 AU - Nicolescu M AU - Moldoveanu G TI - The thermolabile antigen of some reference Leptospira strains from the Pomona serogroup. LA - Eng MH - Animal MH - Antigens, Bacterial/*analysis MH - Heat MH - Immune Sera/*analysis MH - Immunologic Techniques MH - Leptospira/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 780925 DP - 1977 Apr-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 151-5 CY - ROMANIA IP - 2 VI - 36 JC - 8EM EM - 7811 PMID- 354588 CU - 90 SO - Arch Roum Pathol Exp Microbiol 1977 Apr-Jun;36(2):151-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 78234641 AU - Stavri D AU - Moldoveanu G AU - Niculescu D AU - Ionescu MD TI - Antigenic competition between the particulated and soluble fractions of the Leptospira biflexa Patoc I. LA - Eng MH - Animal MH - *Antibody Formation MH - *Antigen-Antibody Reactions MH - Antigens, Bacterial/*analysis MH - Immunologic Techniques MH - Leptospira/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 780925 DP - 1977 Apr-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 125-33 CY - ROMANIA IP - 2 VI - 36 JC - 8EM EM - 7811 PMID- 354586 CU - 90 SO - Arch Roum Pathol Exp Microbiol 1977 Apr-Jun;36(2):125-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 77183364 AU - Miller RB TI - A summary of some of the pathogenetic mechanisms involved in bovine abortion. LA - Eng MH - Abortion, Veterinary/*etiology/genetics MH - Animal MH - Aspergillosis/veterinary MH - Bovine Virus Diarrhea-Mucosal Disease MH - Brucellosis, Bovine MH - Campylobacter fetus MH - Campylobacter Infections/veterinary MH - Cattle MH - Cattle Diseases/*etiology/genetics MH - Chromosome Abnormalities/veterinary MH - Female MH - Fetal Death/veterinary MH - Fetal Diseases/veterinary MH - Leptospirosis/veterinary MH - Listeria Infections/veterinary MH - Male MH - Maternal-Fetal Exchange MH - Pregnancy PT - JOURNAL ARTICLE PT - REVIEW DA - 770718 DP - 1977 Apr IS - 0008-5286 TA - Can Vet J PG - 87-95 CY - CANADA IP - 4 VI - 18 JC - CLS EM - 7709 RF - 86 PMID- 324606 CU - 90 SO - Can Vet J 1977 Apr;18(4):87-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 79013836 AU - Riedemann S AU - Zamora J TI - [Substitution of rabbit serum in the culture medium for Leptospira. Use of bovine amniotic fluid] LA - Spa MH - *Amniotic Fluid MH - Animal MH - Blood MH - Cattle MH - Comparative Study MH - *Culture Media MH - English Abstract MH - Female MH - Leptospira/*growth & development MH - Pregnancy MH - Rabbits/*blood PT - JOURNAL ARTICLE DA - 781129 DP - 1977 Apr-Jun IS - 0034-9771 TA - Rev Latinoam Microbiol PG - 83-6 CY - MEXICO IP - 2 VI - 19 JC - SEP EM - 7901 PMID- 279067 CU - 88 TT - Reemplazo del suero de conejo en medio de cultivo para Leptospira. Empleo de liquido amniotico bovino. EA - A SO - Rev Latinoam Microbiol 1977 Apr-Jun;19(2):83-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 78200507 AU - Brockie RE TI - Leptospiral infections of rodents in the North Island. LA - Eng MH - Animal MH - Leptospirosis/epidemiology/*veterinary MH - Mice MH - New Zealand MH - Rats MH - Rodent Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 780814 DP - 1977 Apr IS - 0048-0169 TA - N Z Vet J PG - 89-90, 95-6 CY - NEW ZEALAND IP - 4 VI - 25 JC - OBZ EM - 7810 PMID- 275701 CU - 88 SO - N Z Vet J 1977 Apr;25(4):89-90, 95-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 78056221 AU - Dragomir AV TI - [Prevention of leptospirosis of swine at a breeding farm] LA - Rus MH - Animal MH - Case Report MH - Female MH - Leptospirosis/*veterinary MH - Moldova MH - Pregnancy MH - Quarantine MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination PT - JOURNAL ARTICLE DA - 780127 DP - 1977 Apr IS - 0042-4846 TA - Veterinariia PG - 58-9 CY - USSR IP - 4 JC - XCC EM - 7803 PMID- 145070 CU - 92 TT - Sluchai leptospiroza svinei na komplekse. SO - Veterinariia 1977 Apr;(4):58-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 77183561 AU - Sramkova L AU - Vanista J AU - Cervova H AU - Polakova L TI - [Serological diagnosis of leptospirosis] LA - Cze MH - Animal MH - Antibodies, Bacterial MH - Antibody Specificity MH - English Abstract MH - Guinea Pigs MH - Human MH - IgM/analysis MH - Leptospirosis/*diagnosis MH - Rabbits MH - Serodiagnosis/methods PT - JOURNAL ARTICLE DA - 770718 DP - 1977 Mar 25 IS - 0008-7335 TA - Cas Lek Cesk PG - 369-73 CY - CZECHOSLOVAKIA IP - 12 VI - 116 JC - CPY EM - 7709 PMID- 861991 TT - K serologicke diagnostice leptospiroz EA - A SO - Cas Lek Cesk 1977 Mar 25;116(12):369-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 77224921 AU - de Geus A AU - Wolff JW AU - Timmer VE TI - Clinical leptospirosis in Kenya (II): A field study in Nyanza Province. LA - Eng MH - Acute Disease MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Kenya MH - Leptospirosis/*epidemiology MH - Male MH - Occupational Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 770922 DP - 1977 Mar IS - 0012-835X TA - East Afr Med J PG - 125-32 CY - KENYA IP - 3 VI - 54 JC - EDG EM - 7711 PMID- 885096 CU - 88 SO - East Afr Med J 1977 Mar;54(3):125-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 77224920 AU - de Geus A AU - Wolff JW AU - Timmer VE TI - Clinical leptospirosis in Kenya (1): a clinical study in Kwale District, Cost Province. LA - Eng MH - Adolescence MH - Adult MH - Human MH - Kenya MH - Leptospirosis/*epidemiology MH - Male MH - Occupational Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 770922 DP - 1977 Mar IS - 0012-835X TA - East Afr Med J PG - 115-24 CY - KENYA IP - 3 VI - 54 JC - EDG EM - 7711 PMID- 885095 CU - 88 SO - East Afr Med J 1977 Mar;54(3):115-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 77201276 AU - Davos D TI - Isolation of leptospira interrogens serotype tarassovi from a pig [letter]. LA - Eng MH - Animal MH - Female MH - Leptospira interrogans/*isolation & purification MH - Swine/*microbiology PT - LETTER DA - 770718 DP - 1977 Mar IS - 0005-0423 TA - Aust Vet J PG - 151-2 SB - M CY - AUSTRALIA IP - 3 VI - 53 JC - 9IE EM - 7709 PMID- 869808 CU - 91 SO - Aust Vet J 1977 Mar;53(3):151-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 77174214 AU - Ellis WA AU - Michna SW TI - Bovine leptospirosis: experimental infection of pregnant heifers with a strain belonging to the Hebdomadis serogroup. LA - Eng MH - Abortion, Veterinary/microbiology MH - Animal MH - Blood/microbiology MH - Cattle MH - Cattle Diseases/immunology/*microbiology MH - Female MH - Fetus/microbiology MH - Fever/veterinary MH - Kidney/microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - Placenta/microbiology MH - Pregnancy MH - Pregnancy Complications/immunology MH - Pregnancy Complications, Infectious/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 770630 DP - 1977 Mar IS - 0034-5288 TA - Res Vet Sci PG - 229-36 SB - M CY - ENGLAND IP - 2 VI - 22 JC - R7D AA - Author EM - 7708 AB - Twenty pregnant heifers were inoculated with a leptospire of the Hebdomadis serogroup. Leptospiraemia was accompanied by pyrexia which lasted from one to five days. Sixteen animals had relapses of fever. One of these aborted and two produced weak calves, one of which was premature. In the heifers, leptospires localised in the placentae, where they were demonstrable for 14-60 days after inoculation, and in the renal tubules for as long as 174 days. They were also demonstrated in liver, kidney and lung from the aborted fetus. Antibodies were detected in susceptible heifers six days after inoculation and maximum titres of up to 1:100,000 developed between 11 and 21 days. A titre of 1:10 was demonstrated in the serum of a premature live calf. These findings indicated that leptospires of the Hebdomadis group were capable of causing abortion in cattle. PMID- 860095 SO - Res Vet Sci 1977 Mar;22(2):229-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 77148656 AU - Ghosh SK AU - Stevenson J TI - Leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Case Report MH - Diagnosis, Differential MH - Human MH - *Leptospirosis/cerebrospinal fluid/diagnosis/therapy MH - Male MH - Middle Age MH - Rats PT - JOURNAL ARTICLE DA - 770525 DP - 1977 Mar IS - 0032-6518 TA - Practitioner PG - 376-81 SB - M CY - ENGLAND IP - 1305 VI - 218 JC - PHQ EM - 7707 PMID- 846927 SO - Practitioner 1977 Mar;218(1305):376-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 77177703 AU - Reichuk EA AU - Soloshenko IZ AU - Chernukha IuG TI - [Cytopathogenic properties of leptospirae in cell cultures of embryonic cow, swine and guinea pig kidney] LA - Rus MH - Animal MH - Cattle MH - *Cells, Cultured MH - Comparative Study MH - Guinea Pigs MH - Kidney/embryology MH - *Leptospira MH - Swine PT - JOURNAL ARTICLE DA - 770622 DP - 1977 Mar IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 144-5 SB - M CY - USSR IP - 3 JC - Y9O EM - 7708 PMID- 558705 CU - 85 TT - Tsitopatogennye svoistva leptospir v kul'turakh kletok pochek embrionov korov, svinei i morskikh svinok SO - Zh Mikrobiol Epidemiol Immunobiol 1977 Mar;(3):144-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 78101887 AU - Ioli A AU - Tredici E AU - Loggini F TI - [Study of the antigenic relationship between Shigella and Leptospira. I. Antigenic relationship between Shigella dysenteriae, type 1 and Leptospira sejroe, Leptospira hardjo and Leptospira sao paulo] LA - Ita MH - Agglutination Tests MH - Animal MH - *Antigen-Antibody Reactions MH - *Antigens, Bacterial/analysis MH - Cross Reactions MH - Leptospira/*immunology MH - Rabbits MH - Shigella dysenteriae/*immunology PT - JOURNAL ARTICLE DA - 780321 DP - 1977 Mar-Apr IS - 0003-472X TA - Ann Sclavo PG - 219-24 CY - ITALY IP - 2 VI - 19 JC - 65C EM - 7805 PMID- 341818 CU - 90 TT - Studio sulla parentela antigene tra Shigelle e Leptospire. I. Parentela antigene tra "Shigella dysenteriae" 1 e "Leptospire sejroe", "hardjo" e "sao paulo". SO - Ann Sclavo 1977 Mar-Apr;19(2):219-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 78200498 AU - Buddle JR AU - Hodges RT TI - Observations on some aspects of the epidemiology of leptospirosis in a herd of pigs. LA - Eng MH - Animal MH - Leptospirosis/epidemiology/veterinary MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 780814 DP - 1977 Mar IS - 0048-0169 TA - N Z Vet J PG - 56, 65-6 CY - NEW ZEALAND IP - 3 VI - 25 JC - OBZ EM - 7810 PMID- 275692 CU - 88 SO - N Z Vet J 1977 Mar;25(3):56, 65-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77203397 AU - Kadlcik K TI - [Immunofluorescent and agglutinating activity on antileptospirosal rabbit sera (author's transl)] LA - Cze MH - *Agglutination MH - Animal MH - Antigens, Bacterial/isolation & purification MH - Chromatography, Gel MH - English Abstract MH - Fluorescent Antibody Technique MH - *Immune Sera MH - Leptospira/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 770812 DP - 1977 Mar IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 110-22 CY - CZECHOSLOVAKIA IP - 2 VI - 26 JC - CSH EM - 7710 RO - M:LBR PMID- 141337 LR - 790213 CU - 92 TT - Imunofluorescencni a aglutinacni aktivita antileptospiroznich kralicich ser. EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1977 Mar;26(2):110-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77099137 AU - van Berge Henegouwen GP AU - Brandt KH AU - Ruben AT AU - van Leusen R TI - Sulphation of bile acids: Liver or kidney [letter]? LA - Eng MH - Bile Acids and Salts/blood/*metabolism MH - Case Report MH - Human MH - Kidney/*metabolism MH - Leptospirosis/metabolism MH - Liver/*metabolism MH - Male MH - Sulfates/*biosynthesis PT - LETTER DA - 770331 DP - 1977 Feb 12 IS - 0140-6736 TA - Lancet PG - 374 SB - A SB - M CY - ENGLAND IP - 8007 VI - 1 JC - L0S EM - 7705 PMID- 64904 CU - 95 SO - Lancet 1977 Feb 12;1(8007):374 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 77127585 AU - Pierce JF AU - Jabbari B AU - Shraberg D TI - Leptospirosis: a neglected cause of nonbacterial meningoencephalitis. LA - Eng MH - Adult MH - Case Report MH - Color MH - Glucose/cerebrospinal fluid MH - Human MH - Intracranial Pressure MH - *Leptospirosis/cerebrospinal fluid MH - Leukocyte Count MH - Male MH - Meningoencephalitis/cerebrospinal fluid/*etiology MH - Middle Age MH - Prognosis PT - JOURNAL ARTICLE DA - 770425 DP - 1977 Feb IS - 0038-4348 TA - South Med J PG - 150-2 SB - A SB - M CY - UNITED STATES IP - 2 VI - 70 JC - UVH AA - Author EM - 7706 AB - Two cases of leptospirosis with different clinical presentations are presented. The importance of recognizing mild, nonicteric and meningoencephalitic forms in order to identify vectors and contaminated areas and prevent further infections is emphasized. Cerebrospinal fluid (CSF) findings in reported cases of leptospirosis are reviewed and possible prognostic implications of CSF xanthrochromia, hypoglycorrhachia, persistent polymorphonuclear leukocytosis, and increased intracranial pressure are discussed. PMID- 841389 SO - South Med J 1977 Feb;70(2):150-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 77130559 AU - Yanagawa R AU - Adachi Y TI - Identification of some Japanese leptospiral strains as serotypes copenhageni and icterohaemorrhagiae by preciptin-absorption test in gel. LA - Eng MH - Agglutination Tests MH - Immunodiffusion MH - Leptospira interrogans/*classification MH - Precipitin Tests MH - Serotyping/methods PT - JOURNAL ARTICLE DA - 770415 DP - 1977 Feb IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 96-103 SB - M CY - GERMANY, WEST IP - 1 VI - 237 JC - Y52 AA - Author EM - 7706 AB - Nine strains of Leptospira belonging to the Icterohaemorrhagiae serogroups isolated in Japan were identified by the precipitin- absorption test in gel. The results of the precipitin-absorption test matched closely with those of the agglutinin-absorption test. Two strains were identified as serotype copenhageni and 7 were serotype icterohaemorrhagiae. Strain Shibaura, which was thought to belong to serotype icterohaemorrhagiae and used in many laboratories in Japan, was corrected as belonging to serotype copenhageni. PMID- 402753 CU - 91 SO - Zentralbl Bakteriol [Orig A] 1977 Feb;237(1):96-103 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 77119073 AU - Smith PC TI - Proposed calfhood immunization program for the commercial dairy herd. LA - Eng MH - Animal MH - Animals, Newborn MH - Bovine Virus Diarrhea-Mucosal Disease/prevention & control MH - Brucellosis, Bovine/prevention & control MH - Cattle MH - Cattle Diseases/*prevention & control MH - Clostridium Infections/prevention & control/veterinary MH - Coronaviridae Infections/prevention & control/veterinary MH - Escherichia coli Infections/prevention & control/veterinary MH - Immunization/*veterinary MH - Infectious Bovine Rhinotracheitis/prevention & control MH - Leptospirosis/prevention & control/veterinary MH - Reoviridae Infections/prevention & control/veterinary MH - Salmonella Infections, Animal/prevention & control PT - JOURNAL ARTICLE PT - REVIEW DA - 770430 DP - 1977 Feb IS - 0022-0302 TA - J Dairy Sci PG - 294-9 SB - M CY - UNITED STATES IP - 2 VI - 60 JC - HWV AA - Author EM - 7706 AB - Immunization programs never will usurp the central role of sound management practices and good nutrition in the disease prevention program of the commercial dairy operation. However, certain immunizations against diseases such as brucellosis, leptospirosis, and clostridial infections should be routine. Other diseases such as infectious bovine rhinotracheitis, bovine virus diarrhea, parainfluenza- 3, colibacillosis, and pasteurellosis should be considered if it can be determined that the herd is infected chronically. The present knowledge of other disease conditions, vaccine effectiveness and safety makes the use of vaccines for other diseases of questionable value. RF - 41 PMID- 190280 CU - 93 SO - J Dairy Sci 1977 Feb;60(2):294-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 78000951 AU - Myers DM AU - Caparo AC AU - Moreno JP TI - Isolation of serotype hardjo and other leptospirae from armadillos in Argentina. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Argentina MH - Armadillos/*microbiology MH - Disease Reservoirs MH - Edentata/*microbiology MH - Kidney/microbiology/pathology MH - Leptospira/immunology/*isolation & purification MH - Nephritis, Interstitial/pathology PT - JOURNAL ARTICLE DA - 771125 DP - 1977 TA - Bull Pan Am Health Organ PG - 131-9 CY - UNITED STATES IP - 2 VI - 11 JC - BSB AA - Author EM - 7801 AB - A serologic, bacteriologic, and histopathologic examination for leptospires was carried out on 89 armadillos (Chaetophractus villosus) from Argentina. Forty-seven per cent of the serum samples yielded positive results when tested by microscopic-agglutination. Predominant agglutination reactions were to the Hebdomadis and Bataviae serogroups. A total of 15 Leptospira isolations (from 16.8 per cent of the animals tested) were obtained from kidney tisse. Nine of the isolates were identified as belonging to the Bataviae group serotypes argentiniensis, paidjan, or bataviae; three other isolates proved to be the Canicola group serotype canicola; two others were Leptospira biflexa strains; and the last isolate was found to be serotype hardjo of the Hebdomadis group. The latter finding represents the first isolation of serotype hardjo from this animal species. Histopathologic examination of kidneys from 11 of the animals yielding pathogenic leptospires permitted a diagnosis of interstitial nephritis. This intersitial nephritis, presenting the characteristic picture of lymphoid infiltration, appeared intense in two animals, moderate in five others, and only slight in the remaining four. These histopathologic findings of chronic nephritis, combined with the high positive serologic and cultural isolation rates, suggest that the armadillo is an important natural reservoir-host for pathogenic leptospirae. PMID- 901969 CU - 90 SO - Bull Pan Am Health Organ 1977;11(2):131-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 77175593 AU - Ramachandran S AU - Perera MV TI - Cardiac and pulmonary involvement in leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Female MH - Human MH - Leptospirosis/mortality/*pathology MH - Lung/*pathology MH - Male MH - Middle Age MH - Myocardium/*pathology PT - JOURNAL ARTICLE DA - 770630 DP - 1977 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 56-9 SB - M CY - ENGLAND IP - 1 VI - 71 JC - WBU AA - Author EM - 7708 AB - The clinico-pathological features of cardiac and pulmonary involvement were studied in seven cases of fatal leptospirosis. Petechial haemorrhages occurred in the heart and pericardium in all cases with blood-stained pericardial effusions in five. Interstitial myocarditis was noted in five patients and probably caused the changing electrocardiographic abnormalities and clinical cardiovascular effects during the illness. Sub-pleural and intrapulmonary haemorrhages occurred in all seven cases with pleural effusions in four. Pulmonary oedema was a striking feature during the early stages of the illness, while in patients surviving the first week of the disease infiltrative and proliferative lesions were common. The latter type of pulmonary changes occurred at a stage when acute renal failure was improving and were not related to the presence and severity of jaundice. The clinico- pathological profile of pulmonary involvement in leptospirosis appears to fall into an adult respiratory distress syndrome and, when present, carries a serious prognosis and would then be a prime factor in mortality. As clinical manifestations of pulmonary involvement appear late during the clinical illness and may be of abrupt onset, auscultatory and radiological surveillance becomes mandatory in severe leptospiral infections. PMID- 871034 SO - Trans R Soc Trop Med Hyg 1977;71(1):56-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 77170542 AU - Khavkin TN AU - Ioffe VA TI - [Intravital pulse photography of microorganisms in a dark field] LA - Rus MH - Leptospira/*cytology MH - Photomicrography/instrumentation/*methods PT - JOURNAL ARTICLE DA - 770630 DP - 1977 Jan-Feb IS - 0026-3656 TA - Mikrobiologiia PG - 179-81 SB - M CY - USSR IP - 1 VI - 46 JC - MZI EM - 7708 PMID- 859461 TT - Prizhiznennoe impul'snoe fotografirovanie mikroorganizmov v temnom pole SO - Mikrobiologiia 1977 Jan-Feb;46(1):179-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 77176291 AU - Matveeva AA AU - Sakharova PU AU - Shabran EK AU - Dragomir AV AU - Nekipelova GA TI - [Etiology of leptospirosis in animals] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/etiology MH - Horse Diseases/etiology MH - Horses MH - Leptospirosis/epidemiology/etiology/*veterinary MH - Mammals MH - Swine MH - Swine Diseases/etiology MH - USSR PT - JOURNAL ARTICLE DA - 770611 DP - 1977 Jan IS - 0042-4846 TA - Veterinariia PG - 61-6 CY - USSR IP - 1 JC - XCC EM - 7708 PMID- 855173 CU - 88 TT - Etiologiia leptospiroza u zhivotnykh SO - Veterinariia 1977 Jan;(1):61-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 77154160 AU - Breitenfeld V AU - Gugic F TI - [Incidence and clinico-biochemical characteristics of liver damage in leptospirosis] LA - Scr MH - Adult MH - Aged MH - Aminotransferases/blood MH - Human MH - Leptospirosis/*complications/enzymology MH - Liver Diseases/enzymology/*etiology MH - Middle Age PT - JOURNAL ARTICLE DA - 770525 DP - 1977 IS - 0001-6047 TA - Acta Med Iugosl PG - 33-42 CY - YUGOSLAVIA IP - 1 VI - 31 JC - 10S EM - 7707 PMID- 848345 TT - Ucestalost i klinicko-biokemijske osebine ostecenja jetre u toku leptospiroze SO - Acta Med Iugosl 1977;31(1):33-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 77153650 AU - Cinco M AU - Stefanelli I TI - Factor analysis of Basovizza serogroup of "Leptospira biflexa". LA - Eng MH - Antigens, Bacterial/analysis MH - Cross Reactions MH - Leptospira interrogans/*classification/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 770520 DP - 1977 IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 337-41 SB - M CY - GERMANY, WEST IP - 2-3 VI - 237 JC - Y52 AA - Author EM - 7707 AB - Factor analysis is performed on serotypes of Basovizza serogroup of "Leptospira biflexa". The results show the arrangement of main factors typical for the members of this serogroup as well as the antigens common with serotypes of the heterologous serogroup. The existence of a main haptene-like factor is also hypothesized. PMID- 848215 SO - Zentralbl Bakteriol [Orig A] 1977;237(2-3):337-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 77113407 AU - Ellis WA AU - O'Brien JJ AU - Neill S AU - Hanna J AU - Bryson DG TI - The isolation of a strain of Leptospira serogroup icterohaemorrhagiae from an aborted bovine foetus. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Fetus/*microbiology MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 770425 DP - 1977 Jan-Feb IS - 0007-1935 TA - Br Vet J PG - 108-9 CY - ENGLAND IP - 1 VI - 133 JC - B5C EM - 7706 PMID- 837199 SO - Br Vet J 1977 Jan-Feb;133(1):108-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 77105262 AU - Newman EC AU - Pool GE TI - Leptospirosis in west Texas. LA - Eng MH - Animal MH - Disease Reservoirs MH - Human MH - Leptospirosis/*epidemiology/transmission MH - Texas MH - Zoonoses PT - JOURNAL ARTICLE DA - 770321 DP - 1977 Jan IS - 0040-4470 TA - Tex Med PG - 75-8 CY - UNITED STATES IP - 1 VI - 73 JC - VNA EM - 7705 PMID- 835099 CU - 88 SO - Tex Med 1977 Jan;73(1):75-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 77085009 AU - Shenberg E AU - Birnbaum S AU - Radrig E AU - Torten M TI - Dynamic changes in the epidemiology of canicola fever in Israel. Natural adaptation of an established serotype to a new reservoir host. LA - Eng MH - Adult MH - Animal MH - Antibodies/analysis MH - Carrier State MH - Case Report MH - Disease Reservoirs MH - Human MH - Israel MH - Leptospira canicola/immunology MH - Leptospirosis/epidemiology/*transmission/veterinary MH - Male MH - Rats/*parasitology MH - Serotyping MH - Swine MH - Swine Diseases/epidemiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 770226 DP - 1977 Jan IS - 0002-9262 TA - Am J Epidemiol PG - 42-8 SB - M CY - UNITED STATES IP - 1 VI - 105 JC - 3H3 AA - Author EM - 7704 AB - Investigation of human leptospirosis caused by the serotype canicola revealed a significant shift in the chain of infection of this disease. The adaptation of an old and well-established serotype to a new and abundant host, the Norway rat, provides a new means for spreading and transferring canicola fever to man and farm animals. The changes in the epidemiology of leptospirosis described should serve as a warning to epidemiologists responsible for suggesting proper prophylactic measures. PMID- 831464 CU - 88 SO - Am J Epidemiol 1977 Jan;105(1):42-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 77082119 AU - Hartman EG TI - [Leptospirosis (author's transl)] LA - Dut MH - Animal MH - Antibodies, Bacterial/analysis MH - Dog Diseases/epidemiology MH - Dogs MH - English Abstract MH - Female MH - Human MH - Kidney/microbiology MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - *Leptospirosis/microbiology/veterinary MH - Male MH - Netherlands MH - Penicillins/therapeutic use MH - Streptomycin/therapeutic use MH - Urine/microbiology MH - Vaccination MH - *Weil's Disease/microbiology/veterinary MH - Zoonoses PT - JOURNAL ARTICLE DA - 770224 DP - 1977 Jan 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 45-52 SB - M CY - NETHERLANDS IP - 1 VI - 102 JC - VRY AA - Author EM - 7704 AB - Leptospirosis is one of the most widely distributed zoonoses. Dogs are the pets in which leptospirosis is most common. The use of diagnostic laboratory procedures is discussed. During the first seven days of the disease, leptospires may be detected in the blood and organs; after the seventh day, they are detectable in the kidney and possibly also in the urine. Examination of the serum for antibodies is possible after the first week of the disease. A clinical diagnosis is often hard to establish. Unlike what used to be the case, infections with L. icterohaemorrhagiae are more common today than those with L. canicola. Infections are more common in male dogs than they are in bitches. In addition to antibiotic therapy, preferably consisting in administration of penicillin and streptomycin, symptomatic treatment is useful. Vaccination should be performed in the spring. Dog are probably of minor importance as a source of human infection in the Netherlands. PMID- 831321 CU - 88 TT - Leptospirose EA - A SO - Tijdschr Diergeneeskd 1977 Jan 1;102(1):45-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 78015257 AU - Kolev V AU - Genchev GA AU - Bogdanov M AU - Venev S AU - Donev A TI - [Studies of the etiology of infectious abortion in cows in Ruse District] LA - Bul MH - Abortion, Veterinary/*etiology/immunology/microbiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Bulgaria MH - Cattle MH - Cattle Diseases/*etiology/immunology/microbiology MH - English Abstract MH - Female MH - Pregnancy PT - JOURNAL ARTICLE DA - 771125 DP - 1977 IS - 0506-8215 TA - Vet Med Nauki PG - 54-60 SB - M CY - BULGARIA IP - 3 VI - 14 JC - XCE AA - Author EM - 7801 AB - A total of 28,159 blood serum samples have been examined for brucellosis, 87--for leptospirosis, 84--for toxoplasmosis, 554--for the presence of rickettsii and neoreckettsii, and 193--for total protein content, albumin, and protein fractions, taken from cows in the course of the years on 40 dairy farms in the district of Rousse. Bacteriologically were examined 349 aborted fetuses, 178 samples of estral secretion, 57 placentae, and 1002 samples of washings and seminal fluid from bulls for vibriosis. Bacteriologic investigations were also carried out on 383 fetuses for salmonellosis, listeriosis, and colibacteriosis, and virologic studies of 398 placentae and parenchymal organs of fetuses. Twenty-eight fetuses were studied parasitologically for toxoplasmosis, and 118 blood smears were examined for hemosporidiosis. It was established that most important in the etiology of the infectious abortions in cows in the district of Rousse were Vibrio organisms. They were found in 36.9 per cent of the studied bovine fetuses and in 24.4 per cent of all materials examined bacteriologically. Only 4 cases were noted of neorickettsii from fetuses and placentae. Serologically, there were 23.6 per cent cases positive for neorickettsiosis, and 12.6 per cent--for Q fever; 56.4 per cent of the investigated sera proved positive for leptospirosis. In 0.8 per cent of the examined fetuses there was Escherichia coli. Abortions in cows were also due to anaplasmosis and francaillelosis; 14.2 per cent of the investigated respective sera were positive for toxoplasmosis. On the days of abortions the amount of total protein was 7.13 mg%, that of albumins--36%, and of globulins--64%. It is considered imperative to elucidate the cause of abortions of infectious nature in cows in connection with the establishing of cattle-breeding complexes. PMID- 562030 CU - 85 TT - Prouchvaniia vurkhu etiologiiata na infektsioznite aborti po kravite v Rusenski okrug. EA - A SO - Vet Med Nauki 1977;14(3):54-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 77130673 AU - Kiktenko VS AU - Shirkovskaia AP AU - Ezhov GI AU - Golub VP TI - [Significance of an increase in the titer of agglutinins in the microagglutination test in leptospirosis] LA - Rus MH - Agglutination Tests MH - Animal MH - Carrier State/diagnosis MH - Cattle MH - Cattle Diseases/diagnosis MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis/veterinary MH - Rodent Diseases/diagnosis MH - Swine MH - Swine Diseases/diagnosis PT - JOURNAL ARTICLE DA - 770415 DP - 1977 IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 70-4 SB - M CY - USSR IP - 1 JC - Y9O AA - Author EM - 7706 AB - The authors considered different views of investigators on the diagnostic antibody titre level in the microagglutination test (MAT) in leptospirosis of man and animals. Some of them took into consideration MAT in low titres (1:10-1:20), and others - in high only (1:400, 1:1000), which gave no possibility to assess the state of leptospirosis morbidity. The authors suggest that the assessment of the level of the titres in single and repeated studies should be approached differentially. In single examination 1:100 and over should be considered as a positive MAT titre for man, 1:200 and over - for cattle, 1:20 and over - for swine, and 1:20 and over for murine rodents. In repeated investigations any level of the titre in case of its dynamics should be taken into consideration. PMID- 557273 CU - 85 TT - K voprosu o znachenii velichiny titra aggliutininov v reaktsii microaggliutinatsii pri leptospiroze EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1977;(1):70-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77126746 AU - Bielaaski A AU - Raeside JI TI - Plasma concentrations of steroid hormones in sows infected experimentally with Leptospira pomona or porcine enterovirus strain T1 in late gestation. LA - Eng MH - Abortion, Veterinary/physiopathology MH - Adrenal Cortex Hormones/*blood MH - Animal MH - Enterovirus Infections/*veterinary MH - Estrone/*blood MH - Female MH - Fetal Death/veterinary MH - Labor MH - Leptospirosis/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/*veterinary MH - Progesterone/*blood MH - Swine MH - Swine Diseases/*blood PT - JOURNAL ARTICLE DA - 770425 DP - 1977 Jan IS - 0034-5288 TA - Res Vet Sci PG - 28-34 SB - M CY - ENGLAND IP - 1 VI - 22 JC - R7D AA - Author EM - 7706 AB - Plasma levels of progesterone, corticosteroids and oestrone were determined during the late stages of pregnancy in four sows experimentally infected with Leptospira pomona and in a group of three sows in which fetuses were inoculated in utero with a strain of porcine enterovirus. Only one of the seven infected sows farrowed at full term. All fetuses were dead and delivery was prolonged in litters infected with the virus. In the sows with leptospirosis almost all piglets were expelled dead or in a weak condition. The amounts of progesterone in plasma were within the normal range and showed a decrease shortly before abortion similar to that observed before parturition in normal animals. The elevation in plasma corticosteroids at normal parturtion was not seen at abortion. An irregular pattern with rising levels of plasma oestrone was found in most sows. Peak levels of oestrone were usually reached close to the time of delivery, but occured earlier in most sows which aborted well before term. In conclusion differences were noted between the endocrine patterns in normal parturition and in abortion caused by infectious agents in sows. PMID- 557224 CU - 85 SO - Res Vet Sci 1977 Jan;22(1):28-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 77113409 AU - Morris JA AU - Gill JE AU - Hussaini SN TI - An examination of the antibodies active in the indirect haemagglutination test for bovine leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*immunology MH - Female MH - Hemagglutination Tests MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 770425 DP - 1977 Jan-Feb IS - 0007-1935 TA - Br Vet J PG - 17-24 CY - ENGLAND IP - 1 VI - 133 JC - B5C EM - 7706 PMID- 556970 CU - 85 SO - Br Vet J 1977 Jan-Feb;133(1):17-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 78079270 AU - Brede HD AU - Heber L AU - Steinbach A TI - Comparative bacteriological survey of imported experimental monkeys. LA - Eng MH - Animal MH - Antibodies/analysis MH - Antibodies, Bacterial/analysis MH - Escherichia coli/isolation & purification MH - Haplorhini/*microbiology/parasitology MH - Leptospira/immunology MH - Nematoda/immunology MH - Quarantine MH - Salmonella typhimurium/isolation & purification MH - Shigella/isolation & purification PT - JOURNAL ARTICLE DA - 780218 DP - 1977 IS - 0066-5665 TA - Arb Paul Ehrlich Inst Georg Speyer Haus Ferdinand Blum Inst Frankf A M PG - 113-7 CY - GERMANY, WEST IP - 71 JC - 6LU EM - 7804 RO - M:CNR PMID- 413486 LR - 900320 CU - 91 SO - Arb Paul Ehrlich Inst Georg Speyer Haus Ferdinand Blum Inst Frankf A M 1977;(71):113-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77245169 AU - Eknoyan G AU - Weinman EJ TI - The kidney and infections. LA - Eng MH - Adult MH - Animal MH - Antibiotics/adverse effects MH - Child MH - Endocarditis, Bacterial/complications MH - Glomerulonephritis/immunology MH - Haplorhini MH - Hepatitis, Viral, Human/complications MH - Human MH - Infection/*complications MH - Kidney/immunology MH - Kidney Diseases/*etiology/immunology MH - Leptospirosis/complications MH - Leukocytes/immunology MH - Malaria/complications MH - Pyelonephritis/immunology MH - Syphilis/complications MH - Tuberculosis, Pulmonary/complications PT - JOURNAL ARTICLE DA - 771014 DP - 1977 TA - Contrib Nephrol PG - 272-89 SB - M CY - SWITZERLAND VI - 7 JC - DQV EM - 7712 PMID- 408098 CU - 91 SO - Contrib Nephrol 1977;7:272-89 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [22 medline neighbors] UI - 77202127 AU - Litvin VIu TI - [Agents of zoonoses and the environment of their habitats. III. Adaptive variability and ecotypes] LA - Rus MH - Adaptation, Physiological MH - Animal MH - DNA/analysis MH - Ecology MH - Erysipelothrix/pathogenicity MH - Francisella tularensis/pathogenicity MH - Genotype MH - Guinea Pigs MH - Human MH - Leptospira/analysis MH - Phenotype MH - Rickettsia prowazekii/pathogenicity MH - Rodentia/microbiology MH - Serotyping MH - Soil Microbiology MH - Variation (Genetics) MH - Virulence MH - Zoonoses/*microbiology PT - JOURNAL ARTICLE DA - 770825 DP - 1977 TA - Biol Nauki PG - 43-9 SB - M CY - USSR IP - 4 JC - A3B EM - 7710 PMID- 405989 CU - 91 TT - Vozbuditeli zonozov i sredy obitaniia. III. Adaptivnaia izmenchivost' i ekotipy. SO - Biol Nauki 1977;(4):43-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 78108012 AU - Karaseva EV AU - Chernukha YuG AU - Sakhartseva TF TI - Results of the investigation of soil for contamination with pathogenic leptospires. LA - Eng MH - Animal MH - Disease Vectors MH - Hamsters MH - Leptospira/*isolation & purification MH - Microtinae MH - *Soil Microbiology PT - JOURNAL ARTICLE DA - 780417 DP - 1977 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 301-4 CY - CZECHOSLOVAKIA IP - 4 VI - 24 JC - F2T AA - Author EM - 7806 AB - In the natural focus of leptospirosis at the lake Nero (Yaroslav region, USSR) 630 samples of soil were investigated for the presence of leptospires. Seven cultures of leptospires were isolated from the soil; five of them were pathogenic (four belonged to the serogroup Grippotyphosa and one to the serogroup Hebdomadis) and two were saprophytic. Among the cultures of pathogenic leptospires isolated from the soil there was observed the same quantitative ratio of serogroups as among cultures obtained from rodents, which suggests that the leptospires circulate from mammals to soil and vice versa. PMID- 342368 CU - 90 SO - Folia Parasitol (Praha) 1977;24(4):301-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 78018594 AU - Johnson RC TI - The spirochetes. LA - Eng MH - Borrelia/physiology/pathogenicity MH - Cell Membrane/ultrastructure MH - Cell Wall/ultrastructure MH - Cytoplasm/ultrastructure MH - Ecology MH - Flagella/ultrastructure MH - Leptospira/physiology MH - Lipids/analysis MH - Spirochaeta/physiology MH - *Spirochaetaceae/isolation & purification/physiology/ultrastructure MH - Treponema/physiology/pathogenicity PT - JOURNAL ARTICLE PT - REVIEW DA - 771130 DP - 1977 IS - 0066-4227 TA - Annu Rev Microbiol PG - 89-106 SB - M CY - UNITED STATES VI - 31 JC - 6DV EM - 7801 RF - 167 PMID- 334048 CU - 90 SO - Annu Rev Microbiol 1977;31:89-106 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77126739 AU - Salt GF AU - Little TW TI - Leptospires isolated from wild mammals caught in the south west of England. LA - Eng MH - Animal MH - Carnivora/microbiology MH - England MH - Hedgehogs/microbiology MH - Leptospira/*isolation & purification MH - Mammals/*microbiology MH - Microtinae/microbiology MH - Rats/microbiology PT - JOURNAL ARTICLE DA - 770425 DP - 1977 Jan IS - 0034-5288 TA - Res Vet Sci PG - 126-7 SB - M CY - ENGLAND IP - 1 VI - 22 JC - R7D AA - Author EM - 7706 AB - Leptospires of the serogroups Australis, Icterohaemorrhagiae, Hebdomadis, Javanica and Pomona were isolated from wildlife caught in the south west of England. PMID- 320639 CU - 90 SO - Res Vet Sci 1977 Jan;22(1):126-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 79180330 AU - Rubin HL TI - Serological incidence of leptospirosis in Florida cattle. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*epidemiology MH - Florida MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 790725 DP - 1977 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 197-200 CY - UNITED STATES IP - 81 JC - PY5 EM - 7909 PMID- 286343 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1977;(81):197-200 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 79180329 AU - Tripathy DN AU - Hanson LE AU - Barten SL AU - Mayer GD AU - Jones FC 3d TI - Variation in response of hamsters to Hebdomadis group of Leptospira. LA - Eng MH - Animal MH - Hamsters MH - Immunosuppression MH - Leptospira/*pathogenicity MH - Leptospirosis/*immunology MH - Species Specificity MH - Virulence PT - JOURNAL ARTICLE DA - 790725 DP - 1977 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 183-95 CY - UNITED STATES IP - 81 JC - PY5 EM - 7909 PMID- 286342 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1977;(81):183-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 79180328 AU - Ellinghausen HC Jr AU - Deyoe BL AU - Nervig RM TI - Leptospirosis in perspective. LA - Eng MH - *Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Cross Reactions MH - Diagnosis, Differential MH - Female MH - Leptospira/immunology MH - Leptospirosis/diagnosis/*veterinary MH - Male MH - Species Specificity PT - JOURNAL ARTICLE DA - 790725 DP - 1977 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 161-82 CY - UNITED STATES IP - 81 JC - PY5 EM - 7909 PMID- 286341 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1977;(81):161-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 78200482 AU - Hodges RT TI - Leptospira interrogans serotype pomona infection in pigs: prevention of leptospiruria by immunisation before exposure to a natural infection. LA - Eng MH - Animal MH - Bacteriuria/prevention & control/*veterinary MH - Immunization/*veterinary MH - Leptospira interrogans/*immunology MH - Leptospirosis/pathology/*veterinary MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 780828 DP - 1977 Jan-Feb IS - 0048-0169 TA - N Z Vet J PG - 33-5 CY - NEW ZEALAND IP - 1-2 VI - 25 JC - OBZ EM - 7810 PMID- 275680 CU - 88 SO - N Z Vet J 1977 Jan-Feb;25(1-2):33-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 78200479 AU - Brockie RE AU - Till DG TI - Leptospira ballum isolated from hedgehogs. LA - Eng MH - Animal MH - Hedgehogs/*microbiology MH - Kidney/microbiology MH - Leptospira/*isolation & purification PT - JOURNAL ARTICLE DA - 780828 DP - 1977 Jan-Feb IS - 0048-0169 TA - N Z Vet J PG - 28-30 CY - NEW ZEALAND IP - 1-2 VI - 25 JC - OBZ EM - 7810 PMID- 275677 CU - 88 SO - N Z Vet J 1977 Jan-Feb;25(1-2):28-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 78200474 AU - Ris DR TI - The serology of calves vaccinated and challenged with Leptospira interrogans serotype pomona. I. Agglutination and complement fixation reactions. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle/*immunology MH - Comparative Study MH - Complement Fixation Tests MH - Female MH - Hemagglutination Tests MH - Leptospira interrogans/*immunology MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 780828 DP - 1977 Jan-Feb IS - 0048-0169 TA - N Z Vet J PG - 10-1 CY - NEW ZEALAND IP - 1-2 VI - 25 JC - OBZ EM - 7810 PMID- 275672 CU - 88 SO - N Z Vet J 1977 Jan-Feb;25(1-2):10-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 77176292 AU - Bobrovskii VI TI - [Prevention and decontamination of farms of swine leptospirosis] LA - Rus MH - Animal MH - Leptospirosis/*prevention & control MH - Methods MH - Russia MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 770611 DP - 1977 Jan IS - 0042-4846 TA - Veterinariia PG - 67-8 CY - USSR IP - 1 JC - XCC EM - 7708 PMID- 140501 CU - 92 TT - Profilaktika i ozdorovlenie khoziaistv ot leptospiroza svinei SO - Veterinariia 1977 Jan;(1):67-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 78240196 AU - Vassilevska M AU - Jankov N AU - Grigorov L TI - A study on the relationship dose-effect in case of gamma-irradiation on leptospira. LA - Eng MH - Dose-Response Relationship, Radiation MH - Gamma Rays MH - Leptospira/*radiation effects PT - JOURNAL ARTICLE DA - 781018 DP - 1977 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 67-72 CY - BULGARIA IP - 1 VI - 19 JC - F19 EM - 7812 PMID- 98416 CU - 91 SO - Folia Med (Plovdiv) 1977;19(1):67-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 78240192 AU - Iankov N AU - Baltova E AU - Vassilevska M TI - Proving the presence of leptospiric antigen in the urine of diseased animals by means of complement fixation test. LA - Eng MH - Animal MH - Antigens, Bacterial/*urine MH - *Complement Fixation Tests MH - Leptospira/*immunology MH - Swine PT - JOURNAL ARTICLE DA - 781018 DP - 1977 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 47-9 CY - BULGARIA IP - 1 VI - 19 JC - F19 EM - 7812 PMID- 98412 CU - 91 SO - Folia Med (Plovdiv) 1977;19(1):47-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 77191003 AU - Kiktenko VS AU - Vlasova NP TI - [Absorption reaction of Leptospira antibodies] LA - Rus MH - Absorption MH - Agglutination Tests/*methods MH - Antibodies, Bacterial/*analysis MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 770723 DP - 1977 IS - 0023-6748 TA - Lab Delo PG - 109-10 CY - USSR IP - 2 JC - KYU EM - 7709 PMID- 68136 CU - 95 TT - Postanovka reaktsii absorptsii leptospiroznykh antitel SO - Lab Delo 1977;(2):109-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 77060714 AU - Ellis WA AU - O'Brien JJ AU - Neill S AU - Hanna J AU - Bryson DG TI - The isolation of a leptospire from an aborted bovine fetus. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Ascitic Fluid/microbiology MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Fetus/*microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 770128 DP - 1976 Dec 4 IS - 0042-4900 TA - Vet Rec PG - 458-9 SB - M CY - ENGLAND IP - 23 VI - 99 JC - XBS EM - 7703 PMID- 997199 CU - 90 SO - Vet Rec 1976 Dec 4;99(23):458-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 77073010 AU - Long HW AU - Walker GS 3d TI - Leptospirosis australis--a case report. LA - Eng MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis MH - Middle Age MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 770216 DP - 1976 Dec IS - 0025-7028 TA - J Med Assoc Ga PG - 449-50 CY - UNITED STATES IP - 12 VI - 65 JC - IZB EM - 7704 PMID- 1033976 CU - 85 SO - J Med Assoc Ga 1976 Dec;65(12):449-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 77174911 AU - Harinasuta C AU - Sornamani S AU - Migasena P AU - Vivatanasesth P AU - Pongpaew P AU - Intarakao C AU - Vudhivai N TI - Socio-economic, health and nutritional status of the villagers in the Nong Wai irrigation area, Khon Kaen, Northeast Thailand. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Child MH - Child, Preschool MH - Deficiency Diseases/epidemiology MH - Female MH - Geography MH - *Health Surveys MH - Human MH - Intestinal Diseases, Parasitic/epidemiology MH - Life Style MH - Male MH - Middle Age MH - *Nutrition Surveys MH - *Socioeconomic Factors MH - Thailand MH - Zoonoses PT - JOURNAL ARTICLE DA - 770630 DP - 1976 Dec IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 601-21 SB - M CY - THAILAND IP - 4 VI - 7 JC - UVN AA - Author EM - 7708 AB - Studies were carried out from June 1974 to May 1975 on the socio- economic status, health and nutritional status of the people in 4 villages, in the irrigation area of the Nong Wai Pioneer Agricultural Project of Khon Kaen Province, Northeast Thailand. The result obtained were compared with those in 2 non-irrigated villages in the same province, in order to identify the health and nutritional problems which might arise during the water resource development in the irrigation area. It was found that in the irrigated villages 90% of the peoples were farmers, while in the non-irrigated villages all were farmers. The socio-economic status of the people in the irrigated villages was much better than those in the non-irrigated ones. The income per family in the former was about three times greater than that in the latter. In the study of the health conditions of the villagers, the vulnerable age group including pre-school children under 7 years of age and school children in the elementary school class 1 and class 2, aged 7-9 years old, served as subjects for investigation. Haematological and physical examinations revealed many children with mild to moderate anaemia, vitamin B2 deficiency and a few cases of hepatomegaly. Anaemic children were found to be more prevalent in the non-irrigated villages than in the irrigated area. The overall parasitic infection rates in children in the irrigated and non- irrigated villages were similar with respect to severity of the infection. Hookworm infection, opisthorchiasis, strongyloidiasis and giardiasis were the leading parasitic infections, while amoebiasis was rare. Ascariasis and trichuriasis were not found. However, the first two helminthic infections had a low grade of intensity. The nutritional status of pre-school children, showed that there were more children with good growth in the irrigated villages than in the non-irrigated one. Serum proteins, albumin and globulin, and urinary urea nitrogen- creatinine ratio revealed normal findings indicating that the children had sufficient protein intake. The results of the urinary hydroxyproline-creatinine index suggested that many of the children in both groups of the villages were at marginal malnutrition status. Surveys on domestic animals including cattle, buffaloes, pigs, and field rats revealed no important zoonotic diseases except leptospirosis in a few rats. Some fish were found to harbour metacercariae of Opisthorchis viverrini, while some snails were positive for cercariae of O. viverrini, Schistosoma spindale, and Echinostoma malayanum. The overall findings indicated that the water resource development by establishing better irrigation, resulted in an improved socio-economic and nutritional status among the villagers, but health conditions and associated parasitic diseases and some nutritional deficiency still existed in the children. However, the findings from this study provide only preliminary data concerning the socio-economic status, health, and nutritional status of the villagers in the irrigation area... PMID- 1030856 CU - 88 SO - Southeast Asian J Trop Med Public Health 1976 Dec;7(4):601-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 77116500 AU - Nowakowski J TI - [Vaccines against leptospirosis] LA - Pol MH - Animal MH - Bacterial Vaccines/*administration & dosage MH - Cattle MH - Cattle Diseases/*prevention & control MH - Leptospirosis/prevention & control/*veterinary MH - Vaccines, Attenuated/administration & dosage PT - JOURNAL ARTICLE DA - 770428 DP - 1976 Dec IS - 0025-8628 TA - Med Weter PG - 707-11 CY - POLAND IP - 12 VI - 32 JC - E56 EM - 7706 PMID- 1017559 LI - R TT - Wspolczesne szczepionki przeciw leptospirozom SO - Med Weter 1976 Dec;32(12):707-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 77107584 AU - Atanasov N AU - Vassilevska M AU - Popov N TI - Electrophoresis of water-insoluble leptospiral proteins and the taxonomy of Leptospira. LA - Eng MH - *Bacterial Proteins MH - Electrophoresis, Polyacrylamide Gel MH - Leptospira/*analysis/classification MH - Molecular Weight MH - Serotyping PT - JOURNAL ARTICLE DA - 770331 DP - 1976 Dec IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 536-42 SB - M CY - GERMANY, WEST IP - 4 VI - 236 JC - Y52 AA - Author EM - 7705 AB - The cellular debris obtained after lysis of Leptospira were solubilized by sodium dodecyl sulfate and studied by polyacrylamide electrophoresis, comparing the molecular weight and relative concentration of the protein bands. The percentage similarity of 30 characteristic bands from 21 Leptospira strains, belonging to the main pathogenic and some saprophytic serogroups, was calculated; A partial matching of the derived dendrogram with the other classifications was observed. PMID- 1015034 SO - Zentralbl Bakteriol [Orig A] 1976 Dec;236(4):536-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 77078192 AU - Wiklik W AU - Skibinska L TI - [Leptospirosis typho-gripposa in 4 children] LA - Pol MH - Adolescence MH - Baths MH - Case Report MH - Child MH - Human MH - Leptospirosis/*epidemiology/etiology MH - Male MH - Poland PT - JOURNAL ARTICLE DA - 770224 DP - 1976 Dec IS - 0031-3939 TA - Pediatr Pol PG - 1471-3 CY - POLAND IP - 12 VI - 51 JC - OW2 EM - 7704 PMID- 1004958 CU - 88 TT - Goraczka blotna (leptospirosis typho-gripposa) u czworga dzieci SO - Pediatr Pol 1976 Dec;51(12):1471-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 77156889 AU - McMenamin RA AU - Davies LM AU - Craswell PW TI - Drug induced interstitial nephritis, hepatitis and exfoliative dermatitis. LA - Eng MH - Acute Disease MH - Adolescence MH - Adult MH - Allopurinol/*adverse effects MH - Case Report MH - Dermatitis, Exfoliative/*chemically induced MH - Drug Therapy, Combination/adverse effects MH - Hepatitis, Toxic/*etiology MH - Human MH - Male MH - Middle Age MH - Nephritis, Interstitial/*chemically induced MH - Phenindione/*adverse effects PT - JOURNAL ARTICLE DA - 770512 DP - 1976 Dec IS - 0004-8291 TA - Aust N Z J Med PG - 583-7 SB - M CY - AUSTRALIA IP - 6 VI - 6 JC - 9H9 AA - Author EM - 7707 AB - Acute interstitial nephritis associated with hepatitis, exfoliative dermatitis, fever and eosinophilia is uncommon. The syndrome has been described previously in association with phenindione administration, leptospirosis and heavy metal poisoning. Four cases are described, two of which were due to phenindione sensitivity. The other two patients had been exposed to a number of toxins including allopurinol, frusemide, chlorothiazide and methyldopa so that the exact aetiological agent is unclear. Interstitial nephritis should be considered as a cause of acute renal failure in patients with other features of drug hypersensitivity. PMID- 139882 CU - 92 SO - Aust N Z J Med 1976 Dec;6(6):583-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 77060701 AU - Ellis WA AU - Michna SW TI - Bovine leptospirosis: demonstration of leptospires of the Hebdomadis serogroup in aborted fetuses and a premature calf. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Animal MH - Brain/microbiology MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Fetus/*microbiology MH - Kidney/microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Liver/microbiology MH - Pregnancy PT - JOURNAL ARTICLE DA - 770129 DP - 1976 Nov 27 IS - 0042-4900 TA - Vet Rec PG - 430-2 SB - M CY - ENGLAND IP - 22 VI - 99 JC - XBS AA - Author EM - 7703 AB - Leptospires were demonstrated in five aborted fetuses and in a premature calf. Evidence is presented to indicate that a member of the Hebdomadis serogroup was the causative agent. PMID- 997189 SO - Vet Rec 1976 Nov 27;99(22):430-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 77082754 AU - Ellis WA AU - Michna SW TI - Bovine leptospirosis: infection by the Hebdomadis serogroup and abortion-A herd study. LA - Eng MH - Abortion, Veterinary/*epidemiology/immunology MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*epidemiology/immunology MH - Female MH - Leptospira/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Pregnancy MH - Seasons PT - JOURNAL ARTICLE DA - 770216 DP - 1976 Nov 20 IS - 0042-4900 TA - Vet Rec PG - 409-12 SB - M CY - ENGLAND IP - 21 VI - 99 JC - XBS AA - Author EM - 7704 AB - A possible relationship is demonstrated between infection of cattle by the Hebdomadis serogroup of Leptospira and abortion of undiagnosed aetiology. This association is based on (1) The occurrence of a much higher incidence of antibodies to serotype sejroe in herds with a history of undiagnosed abortion than in other groups of cattle tested. (2) A relationship between the incidence of cows with antibody titres to sejroe and the incidence of abortion of unknown aetiology in 29 herds during an 18 month model period. PMID- 1006960 CU - 88 SO - Vet Rec 1976 Nov 20;99(21):409-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 77060693 AU - Ellis WA AU - Michno SW TI - Bovine leptospirosis: a serological and clinical study. LA - Eng MH - Abortion, Veterinary/immunology MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*immunology MH - Female MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/*veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 770129 DP - 1976 Nov 13 IS - 0042-4900 TA - Vet Rec PG - 387-91 SB - M CY - ENGLAND IP - 20 VI - 99 JC - XBS AA - Author EM - 7703 AB - Antibodies to serotypes representing one or more of 10 Leptospira serogroups were detected in the sera of 1766 (49-1 per cent) cows and heifers out of a total of 3600 sera tested. Infection by the Hebdomadis serogroup was the predominant infection; antibodies to serotype sejroe were found in 1503 (41-8 per cent) sera. Antibodies to the Icterohaemorrhagiae (7-7 per cent) and Balllm (7-3 per cent) serogroups were the next most common, while antibodies to the Australis, Javanica, Canicola, Panama, Cynopteri, Pyrogenes and Autumnalis serogroups were detected in a small number of animals. Only the Hebdomadis and Icterohaemorrhagiae serogroups were associated with clinical disease. PMID- 997182 SO - Vet Rec 1976 Nov 13;99(20):387-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77060686 AU - Ellis WA AU - O'Brien JJ AU - Pearson JK AU - Collins DS TI - Bovine leptospirosis: infection by the Hebdomadis serogroup and mastitis. LA - Eng MH - Animal MH - Cattle MH - Female MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - Mastitis, Bovine/*etiology/immunology/microbiology PT - JOURNAL ARTICLE DA - 770128 DP - 1976 Nov 6 IS - 0042-4900 TA - Vet Rec PG - 368-70 SB - M CY - ENGLAND IP - 19 VI - 99 JC - XBS AA - Author EM - 7703 AB - An outbreak of mastitis involving approximately 70 out of 140 cows over a two-month period is described. Common mastitis pathogens were not incriminated. Leptospires belonging to the Hebdomadis serogroup were isolated from the milk of three out of five cows and the blood of two of those cows. PMID- 997178 SO - Vet Rec 1976 Nov 6;99(19):368-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 77147553 AU - Blackmore DK AU - Marshall RB AU - Ingram BR TI - An epidemiological investigation of leptospirosis at an artifical breeding centre. LA - Eng MH - Animal MH - Breeding MH - Cattle MH - Cattle Diseases/*epidemiology MH - Disease Reservoirs/*veterinary MH - Female MH - Human MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - New Zealand MH - Rabbits MH - Rats MH - Sheep MH - Sheep Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 770520 DP - 1976 Nov IS - 0048-0169 TA - N Z Vet J PG - 253-62 CY - NEW ZEALAND IP - 11 VI - 24 JC - OBZ EM - 7707 PMID- 1071463 CU - 88 SO - N Z Vet J 1976 Nov;24(11):253-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 77195775 AU - Zavala Velazquez J AU - Caballero Guerrero C AU - Sanchez Vazquez I TI - [Leptospirosis in the state of Chiapas, Mexico (preliminary report)] LA - Spa MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Cats MH - Child MH - Child, Preschool MH - Disease Reservoirs MH - Dogs MH - English Abstract MH - Female MH - Human MH - Infant MH - Infant, Newborn MH - Leptospirosis/*epidemiology/veterinary MH - Male MH - Mexico MH - Middle Age MH - Rats PT - JOURNAL ARTICLE DA - 770718 DP - 1976 Nov-Dec IS - 0036-3634 TA - Salud Publica Mex PG - 989-98 CY - MEXICO IP - 6 VI - 18 JC - UY1 EM - 7709 PMID- 1027144 CU - 88 TT - Leptospirosis en el estado de Chiapas, Mexico (informe preliminar) EA - A SO - Salud Publica Mex 1976 Nov-Dec;18(6):989-98 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77174192 AU - Little TA AU - Salt GF TI - The experimental infection of calves with a British leptospire of the Pomona serogroup. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*etiology MH - Fever/veterinary MH - Great Britain MH - Hemoglobinuria/veterinary MH - Leptospira MH - Leptospirosis/etiology/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 770630 DP - 1976 Nov IS - 0034-5288 TA - Res Vet Sci PG - 363-4 SB - M CY - ENGLAND IP - 3 VI - 21 JC - R7D AA - Author EM - 7708 AB - Two calves were infected with a British leptospire of the Pomona serogroup. Both showed symptoms of anorexia and fever and one had marked haemoglobinurea and leptospiruria. The serum antibody titres rose rapidly in both calves. PMID- 1025640 SO - Res Vet Sci 1976 Nov;21(3):363-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 77107567 AU - Cinco Del Fabbro M AU - Sottocasa GL TI - Studies on the role of sodium in the metabolism of halophilic leptospirae. LA - Eng MH - Leptospira/growth & development/*metabolism MH - Oxygen Consumption MH - Seawater MH - Sodium/*metabolism PT - JOURNAL ARTICLE DA - 770331 DP - 1976 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 354-8 SB - M CY - GERMANY, WEST IP - 2-3 VI - 236 JC - Y52 AA - Author EM - 7705 AB - Data from studies of the metabolic mechanism of the sodium dependence of halophilic leptospirae revealed that the presence of sodium - 1) has no effect on the oxygen uptake when the microorganism is oxidizing endogeneous and exogeneous substrates; 2) is not involved in the multiplication phase; but 3) is of importance for keeping the cell structure intact. PMID- 1015024 SO - Zentralbl Bakteriol [Orig A] 1976 Nov;236(2-3):354-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77107566 AU - Shishkina ZS AU - Baryshev PM AU - Chernukha YG AU - Kokovin IL TI - Formation of antibodies and immunoglobulins of various classes in persons vaccinated with warm antileptospirosis polyvalent vaccine. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Antibodies, Bacterial/*biosynthesis MH - Child MH - Female MH - Human MH - IgG/biosynthesis MH - IgM/biosynthesis MH - Immunoglobulins/*biosynthesis MH - Leptospirosis/*immunology/prevention & control MH - Male MH - Middle Age MH - Vaccination PT - JOURNAL ARTICLE DA - 770331 DP - 1976 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 344-53 SB - M CY - GERMANY, WEST IP - 2-3 VI - 236 JC - Y52 AA - Author EM - 7705 AB - The results of the observations of 2 groups of 372 persons during 10 months showed that a twofold inoculation of corpuscular heated 6-valent antileptospiral vaccine ensures the formation of 19S-antibodies. The ratio 19S/7S antibodies was determined by inactivation of IgM agglutinins with the help of 2-mercaptoethanol. Quantitative content of immunolglobulins (G, A and M) was determined in parallel with the reaction of agglutination by the method of simple radial diffusion. Immunoglobulins of the class M in the serum of vaccinated persons increased as compared with control, whereas the content of IgG did not rise and that of IgA decreased. PMID- 1015023 SO - Zentralbl Bakteriol [Orig A] 1976 Nov;236(2-3):344-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 77107565 AU - Chernukha YG AU - Shishkina ZS AU - Baryshev PM AU - Kokovin IL TI - The dynamics of IgM- and IgG-antibodies in leptospiral infection in man. LA - Eng MH - Agglutination Tests MH - Cross Reactions MH - Human MH - IgG/*analysis/biosynthesis MH - IgM/*analysis/biosynthesis MH - Leptospira/immunology MH - Leptospirosis/*immunology MH - Serotyping MH - Time Factors PT - JOURNAL ARTICLE DA - 770331 DP - 1976 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 336-43 SB - M CY - GERMANY, WEST IP - 2-3 VI - 236 JC - Y52 AA - Author EM - 7705 AB - The dynamics of specific agglutinating antibodies belonging to different classes of immunoglobulins in 1047 blood sera of 669 patients and persons who had recovered from leptospirosis was studied. 19S and 7S antibodies were found in sera of patients with simultaneous presence of Pomona and Grippotyphosa. The character of syntesis of specific leptospiral IgM and IgG antibodies correlated, but the concentration of the IgG was much lower. As a rule, IgM antibodies had a wide range of cross-reactions with leptospires of heterologous serogroups. However, IgG-antibodies in 85% of cases reacted with homologous leptospires only. PMID- 1015022 CU - 90 SO - Zentralbl Bakteriol [Orig A] 1976 Nov;236(2-3):336-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77107564 AU - Kida H AU - Watanabe H AU - Yamamoto S AU - Yanagawa R TI - Immunological and morphological analysis of sodium dodecyl sulfate extract of Leptospira. LA - Eng MH - Antigen-Antibody Reactions MH - Antigens, Bacterial/*analysis MH - Leptospira interrogans/*immunology/ultrastructure MH - Microscopy, Electron MH - Sodium Dodecyl Sulfate MH - Subcellular Fractions/immunology/ultrastructure PT - JOURNAL ARTICLE DA - 770331 DP - 1976 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 328-35 SB - M CY - GERMANY, WEST IP - 2-3 VI - 236 JC - Y52 AA - Author EM - 7705 AB - Sodium dodecyl sulfate (SDS) extract of Leptospira interrogans serotype icterohaemorrhagiae strain Shibaura was fractionated by rate zonal centrifugation in sucrose density gradient, and the fractions were analysed immunologically and morphologically. Two main peaks of antigenic activities were obtained. The first peak showed activities of strong indirect hemagglutination (IHA), weak complement fixation (CF), and low production of agglutinin in mice, and produced 5 precipitin lines in immunodiffusion with homologous strain antiserum. It gave only partial protection to guinea pigs. No recognizable structural components were found electron microscopically in the first peak. The second peak, on the other hand, showed no IHA activity, strong CF activity, high production of agglutinin in mice, and produced no precipitin line in immunodiffusion. It gave complete protection to guinea pigs. Membrane fragments of the enveloping sheath were found electron microscopically in the second peak. The protective activity of SDS extract of leptospira was thus intimately associated with the activityes of agglutinin production and CF, as well as with the membranous structures of the enveloping sheath. PMID- 1015021 SO - Zentralbl Bakteriol [Orig A] 1976 Nov;236(2-3):328-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 77107563 AU - Manev C TI - Serological characteristics of the Leptospira serogroup Pomona. II. Changes in the agglutination and absorption properties of the reference strains after formalin- and heat-inactivation. LA - Eng MH - Absorption MH - Agglutination Tests MH - Antigen-Antibody Reactions MH - *Antigens, Bacterial MH - Drug Stability MH - Formaldehyde MH - Heat MH - Leptospira/classification/*immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 770331 DP - 1976 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 323-7 SB - M CY - GERMANY, WEST IP - 2-3 VI - 236 JC - Y52 AA - Author EM - 7705 AB - After formalin or heat-inactivation for 30 minutes at 56 degrees C, the absorption properties of some Pomona serogroup strains diminish, which indicates that they have thermolabile (Pomona, CZ 299U and LT 796) or formalin-labile (Pomona and 5621) minor antigenic factors. The agglutination properties of the various strains change differently after inactivation though not in parallel with the absorption properties. PMID- 1015020 CU - 90 SO - Zentralbl Bakteriol [Orig A] 1976 Nov;236(2-3):323-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 77107562 AU - Manev C TI - Serological characteristics of the Leptospira serogroup Pomona. I. Factor analysis of the reference strains. LA - Eng MH - Absorption MH - Agglutination Tests MH - Animal MH - Antigen-Antibody Reactions MH - Antigens, Bacterial MH - Drug Stability MH - Heat MH - Leptospira/*classification/immunology MH - Serotyping/methods PT - JOURNAL ARTICLE DA - 770331 DP - 1976 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 316-22 SB - M CY - GERMANY, WEST IP - 2-3 VI - 236 JC - Y52 AA - Author EM - 7705 AB - The factor analysis of the Leptospirae of the Pomona serogroup discloses the presence of 4 main factors in this group on the basis of which 4 serovars, namely pomona, mozdok, tropica and proechimys may be accepted in this group. It is proposed that the Monjakov and the LT 1026 strains be referred to the pomona serovar. One of the established main antigens (P-4) is of the complex nature containing both thermostable and thermolabile compounds. PMID- 1015019 SO - Zentralbl Bakteriol [Orig A] 1976 Nov;236(2-3):316-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 77106619 AU - Sokol AS AU - Vozianova ZhI AU - Kuz'minskii NP AU - Dekhtiarenko OM AU - Shvets ET TI - [Clinical characteristics of icterohemorrhagic leptospirosis] LA - Rus MH - Adult MH - Case Report MH - English Abstract MH - Human MH - Kidney/pathology MH - Lung/pathology MH - Male MH - Middle Age MH - *Weil's Disease/diagnosis/pathology PT - JOURNAL ARTICLE DA - 770321 DP - 1976 Nov IS - 0049-6804 TA - Vrach Delo PG - 146-50 CY - USSR IP - 11 JC - XLS EM - 7705 PMID- 1014547 TT - Klinicheskie osobennosti ikterogemorrahicheskogo leptospirozapiroza EA - A SO - Vrach Delo 1976 Nov;(11):146-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 77084219 AU - Prokopchakova G AU - Pospishil R TI - [Leptospirosis in rodents in the old natural focus of Eastern Slovakia] LA - Rus MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial MH - Czechoslovakia MH - *Disease Reservoirs MH - English Abstract MH - Leptospira/immunology MH - Leptospirosis/immunology/microbiology/*veterinary MH - Rodent Diseases/*immunology/microbiology MH - Rodentia MH - Species Specificity PT - JOURNAL ARTICLE DA - 770226 DP - 1976 Nov IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 47-8 SB - M CY - USSR IP - 11 JC - Y9O AA - Author EM - 7704 AB - A total of 770 rodents (40 rats, 100 hamsters and 630 rodents) were serologicall examined in the old natural foci in some of the Eastern Slovakia regions; there were 10.6% of positive reactions to Leptospirosis in dilutions ranging from 1 : 100 to 1 : 1600. In rats 17 sers (40%) proved to be positive to leptospira, mostly reacting with the L. icterohaemorrhagiae. A positive reaction with the leptospira antigen was found in 13 sera (15%) of hamsters; the sera reacted with the Leptospira grypposa more frequently than with the L. serjoe. In the group of small rodents the greatest number of positive reactions to leptospirosis was obtained in microtus arvalis (10.7%); the sera reacted most frequently with L. grippotyphosa and L. serjoe. As many as 9 serological types were revealed in the group examined. PMID- 1007726 TT - O leptospiroze u gryzunov v starom pripodnom ochage na territorii Vostochnoi Slovakii EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1976 Nov;(11):47-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 77074113 AU - Painter GM AU - Ellinghausen HC Jr TI - Immunising potency of Leptospira interrogans serotype canicola after heat inactivation at different temperatures. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - *Bacterial Vaccines MH - Comparative Study MH - Drug Screening MH - Hamsters MH - *Heat MH - Leptospira interrogans/*immunology/isolation & purification/pathogenicity MH - Leptospirosis/*prevention & control MH - Mesocricetus MH - Urine/microbiology MH - Virulence PT - JOURNAL ARTICLE DA - 770224 DP - 1976 Nov IS - 0022-2615 TA - J Med Microbiol PG - 487-92 SB - M CY - ENGLAND IP - 4 VI - 9 JC - J2N AA - Author EM - 7704 AB - The immunogenicity of Leptospira interrogans serotype canicola suspensions inactivated by various degrees of heat exposure was examined in hamsters. No differences between leptospires killed at 50 degrees C and at 98 degrees C were shown. After exposure to 121 degrees C, suspensions retained their ability to protect against lethal infections but lost their ability to prevent leptospiruria. Tests with vaccines inactivated at or below 98 degrees C showed that the doses required for complete protection varied with the interval between vaccination and challenge. Larger doses were required to prevent the development of leptospiruria than to prevent death. PMID- 1003455 CU - 90 SO - J Med Microbiol 1976 Nov;9(4):487-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 77046513 AU - Hussaini SN TI - A comparative study on the use of whey and serum for microscopic agglutination test for the detection of Leptospira antibodies. LA - Eng MH - *Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle/*immunology MH - Comparative Study MH - Female MH - Leptospira/*immunology MH - Milk/*immunology PT - JOURNAL ARTICLE DA - 770125 DP - 1976 Nov-Dec IS - 0007-1935 TA - Br Vet J PG - 621-6 CY - ENGLAND IP - 6 VI - 132 JC - B5C EM - 7703 PMID- 990893 SO - Br Vet J 1976 Nov-Dec;132(6):621-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 77116489 AU - Gorska I AU - Kopczewski A AU - Krolak M TI - [Level of antibodies against Leptospira in sera of dogs in Gdansk] LA - Pol MH - Animal MH - Antibodies, Bacterial/*analysis MH - Brucella abortus/immunology MH - Brucellosis/*veterinary MH - Dog Diseases/immunology MH - Dogs/*immunology MH - English Abstract MH - Female MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospirosis/*veterinary MH - Male MH - Poland PT - JOURNAL ARTICLE DA - 770428 DP - 1976 Nov IS - 0025-8628 TA - Med Weter PG - 672-5 CY - POLAND IP - 11 VI - 32 JC - E56 EM - 7706 PMID- 828112 CU - 91 LI - R TT - Poziom przeciwcial leptospirowych w surowicy krwi psow w Gdansku EA - A SO - Med Weter 1976 Nov;32(11):672-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76262752 AU - McDiarmid A TI - Some research needs in the zoonoses. pp. 369-78. LA - Eng MH - Animal MH - Bird Diseases/transmission MH - Birds MH - Brucellosis/veterinary MH - Carnivora MH - Cattle MH - Deer MH - Hedgehogs MH - Lagomorpha MH - Leptospirosis/transmission/veterinary MH - Louping Ill/transmission MH - Mycobacterium avium MH - Mycobacterium bovis MH - Mycobacterium Infections/veterinary MH - Research MH - Salmonella Infections, Animal/transmission MH - Sheep MH - Tuberculosis, Bovine/transmission MH - *Zoonoses PT - MONOGRAPH DA - 761029 TA - In: Page LA, ed. Wildlife diseases. New York, Plenum Press, 1976. W3 IN9323 1975w. CY - FRANCE JC - IDM EM - 7612 PMID- 784550 CU - 90 CA - W3 IN9323 1975w SO - In: Page LA, ed. Wildlife diseases. New York, Plenum Press, 1976. W3 IN9323 1975w. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 76262749 AU - Soldati G AU - Pavesi M TI - Research on infectious and parasitic agents in foxes in the Modenese Apennines. pp. 527-8. LA - Eng MH - Animal MH - Dermatomycoses/veterinary MH - *Foxes MH - Helminthiasis/veterinary MH - Italy MH - Leptospirosis/veterinary PT - MONOGRAPH DA - 761029 TA - In: Page LA, ed. Wildlife diseases. New York, Plenum Press, 1976. W3 IN9323 1975w. CY - FRANCE JC - IDM EM - 7612 PMID- 784547 CU - 90 CA - W3 IN9323 1975w SO - In: Page LA, ed. Wildlife diseases. New York, Plenum Press, 1976. W3 IN9323 1975w. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 77023130 AU - Burke BJ AU - Searle JF AU - Mattingly D TI - Leptospirosis presenting with profuse haemoptysis. LA - Eng MH - Adolescence MH - Case Report MH - Chronic Disease MH - Hemoptysis/*complications MH - Human MH - Leptospirosis/*complications MH - Male PT - JOURNAL ARTICLE DA - 770103 DP - 1976 Oct 23 IS - 0007-1447 TA - Br Med J PG - 982 SB - A SB - M CY - ENGLAND IP - 6042 VI - 2 JC - B4W EM - 7702 PMID- 974717 SO - Br Med J 1976 Oct 23;2(6042):982 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 77152609 AU - Rudoi FD TI - [Hepato-renal form of leptospirosis] LA - Rus MH - Adult MH - Case Report MH - Human MH - Kidney Diseases/*complications MH - Leptospirosis/*complications MH - Liver Diseases/*complications MH - Male MH - Occupational Diseases PT - JOURNAL ARTICLE DA - 770512 DP - 1976 Oct IS - 0049-6804 TA - Vrach Delo PG - 145 CY - USSR IP - 10 JC - XLS EM - 7707 PMID- 1022020 TT - Gepato-renal'naia forma leptospiroza SO - Vrach Delo 1976 Oct;(10):145 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 77098397 AU - Belov GF AU - Kunina NA AU - Sakharova EG TI - [Differential diagnosis of acute forms of viral hepatitis and jaundice variants of nonicteric leptospirosis] LA - Rus MH - Adult MH - Case Report MH - Diagnosis, Differential MH - Hepatitis, Viral, Human/complications/*diagnosis MH - Human MH - Jaundice/*diagnosis/etiology MH - Leptospirosis/complications/*diagnosis MH - Male PT - JOURNAL ARTICLE DA - 770331 DP - 1976 Oct IS - 0023-2149 TA - Klin Med (Mosk) PG - 75-8 CY - USSR IP - 10 VI - 54 JC - KW2 EM - 7705 PMID- 1011731 TT - O differentsial'noi diagnostike ostrykh form virusnogo gepatita i zheltushnykh variantov bezzheltushnogo liptospiroza SO - Klin Med (Mosk) 1976 Oct;54(10):75-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 77028773 AU - Azuma I AU - Takeda K AU - Yamamura Y AU - Yanagihara Y AU - Mifuchi I TI - Occurrence of 3-O-methylmannose in the polysaccharide of Leptospira biflexa Urawa. LA - Eng MH - Chromatography, Gas MH - Leptospira/*analysis MH - Methylglycosides/*analysis MH - Methylmannosides/*analysis MH - Polysaccharides, Bacterial/*analysis MH - Spectrum Analysis, Mass PT - JOURNAL ARTICLE DA - 761223 DP - 1976 Oct IS - 0021-9193 TA - J Bacteriol PG - 492-4 SB - M CY - UNITED STATES IP - 1 VI - 128 JC - HH3 EM - 7702 PMID- 977543 CU - 90 SO - J Bacteriol 1976 Oct;128(1):492-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 77030934 AU - Morrison WI AU - Wright NG TI - Canine leptospirosis: an immunopathological study of interstitial nephritis due to Leptospira canicola. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/analysis MH - Dog Diseases/*immunology/pathology MH - Dogs MH - Female MH - Fluorescent Antibody Technique MH - IgG/analysis MH - IgM/analysis MH - Kidney/immunology/pathology MH - *Leptospira canicola MH - Leptospirosis/immunology/pathology/*veterinary MH - Male MH - Nephritis, Interstitial/immunology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 770103 DP - 1976 Oct IS - 0022-3417 TA - J Pathol PG - 83-9 SB - M CY - ENGLAND IP - 2 VI - 120 JC - JLB AA - Author EM - 7702 AB - In an attempt to define the pathogenetic mechanisms involved in acute interstitial nephritis due to Leptospira canicola the kidneys of 14 dogs were subjected to histological immunofluorescence and elution studies. Leptospiral antigen was found in three sites within the kidney; as discrete organisms in the proximal tubules, as granular deposits in the cytoplasm of macrophages and in large extracellular clumps in the interstitium. Deposits of IgG were also detected in the latter site and in plasma cells found in the surrounding cellular infiltrate. Anti-leptospiral antibody, mainly of the IgG class, was detected in renal eluates using both agglutination-lysis and indirect immunofluorescence. From these findings it was considered that the cellular infiltrates found in the kidneys of dogs suffering from acute leptospiral nephritis have two main functions; firstly, the local production of anti-leptospiral antibody and, secondly, phagocytosis. PMID- 789837 CU - 90 SO - J Pathol 1976 Oct;120(2):83-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 77126975 AU - Prodrom I AU - Raileanu I AU - Popa O AU - Radu T AU - Voiculescu G AU - Cretu G TI - [Therapeutic considerations on severe leptospirosis] LA - Rum MH - Adult MH - Aged MH - Case Report MH - Disseminated Intravascular Coagulation/prevention & control MH - English Abstract MH - Furosemide/*therapeutic use MH - Heparin/therapeutic use MH - Human MH - Kidney Failure, Acute/*drug therapy/etiology MH - Leptospirosis/complications/*drug therapy MH - Male PT - JOURNAL ARTICLE DA - 770428 DP - 1976 Oct-Dec IS - 0376-4494 TA - Rev Ig [Bacteriol] PG - 241-5 SB - M CY - ROMANIA IP - 4 VI - 21 JC - S7C AA - Author EM - 7706 AB - The present paper reports on the results obtained by intravenous administration of furosemide which shortened the period of oliguria in the course of acute renal insufficiency in leptospirosis. The criteria of administration of heparin for preventing the intravascular disseminated coagulation syndrome in leptospirosis are discussed. PMID- 138928 CU - 92 TT - Consideratii terapeutice in leptospiroza grava EA - A SO - Rev Ig [Bacteriol] 1976 Oct-Dec;21(4):241-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77084177 AU - Vlasova NP AU - Kiktenko VS TI - [Antigenic structure of saprophytic leptospirae and their classification] LA - Rus MH - Agglutination Tests MH - *Antigens, Bacterial/analysis MH - Armenia MH - Cross Reactions MH - English Abstract MH - Leptospira/*classification/immunology/pathogenicity MH - Water Microbiology PT - JOURNAL ARTICLE DA - 770226 DP - 1976 Oct IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 113-6 SB - M CY - USSR IP - 10 JC - Y9O AA - Author EM - 7704 AB - The authors present the results of study of the serological properties of 46 strains of saprophytic leptospirae of different origin. On the basis of the affinity of the antigenic structure detected in the cross microagglutination reaction (MAR) 38 strains under study were united into 8 serological groups; the rest 8 strains were serologically independent in this reaction. The fact that 9 strains of water leptospirae isolated in the Armenian SSR belonged to one serological group was proved in the cross MAR and the test of aglutinin adsorption. This serological group was new and was named L. armenica. Five individual serological types of saprophytic leptospirae were differentiated in its composition. Comparative study of the serological interrelations between the group of strains isolated in Armenia and the strains of some serological groups and serological types the closest serological connections were noted in the K-1030 (serological group Armenica) and Bovedo (serological group Andamana) strains. It is believed that the existing division of the saprophytic leptospirae into two serological groups (Semaranga and Andamana) required widening and supplement by new serological groups and serological types. PMID- 137641 CU - 92 TT - Ob antigennoi strukture saprofitnykh leptospir i ikh klassifikatsii EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1976 Oct;(10):113-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 76239267 AU - Abdussalam M TI - The problem of leptospirosis in the world. pp. 131-42. LA - Eng MH - Animal MH - Disease Reservoirs/veterinary MH - Human MH - Immunization MH - International Cooperation MH - Leptospira/classification/immunology MH - Leptospirosis/*epidemiology/prevention & control/veterinary MH - Microtinae MH - Rodent Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology MH - Water Microbiology PT - MONOGRAPH DA - 760925 TA - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. CY - UNITED STATES JC - IDM EM - 7611 PMID- 781123 CU - 90 CA - W1 PA443 no.316 1976 SO - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 76239261 AU - Szyfres B TI - Leptospirosis as an animal and public health problem in Latin America and the Caribbean area. pp. 115-30. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Reservoirs MH - Dog Diseases/epidemiology MH - Dogs MH - Female MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Male MH - Panama MH - *Public Health MH - Puerto Rico MH - Sheep MH - Sheep Diseases/epidemiology MH - South America MH - Swine MH - Swine Diseases/epidemiology MH - West Indies MH - Zoonoses/epidemiology PT - MONOGRAPH PT - REVIEW DA - 760925 TA - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. CY - UNITED STATES JC - IDM EM - 7611 RF - 64 PMID- 781117 CU - 90 CA - W1 PA443 no.316 1976 SO - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [194 medline neighbors] UI - 76239258 AU - Blenden DC TI - Epidemiologic aspects of leptospirosis. LA - Eng MH - Animal MH - Animals, Domestic MH - Carrier State/veterinary MH - Disease Reservoirs MH - Female MH - Human MH - Humidity MH - Leptospira/growth & development MH - Leptospirosis/*epidemiology/transmission/veterinary MH - Male MH - Population Density MH - Pregnancy MH - Weather PT - MONOGRAPH DA - 760925 TA - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. PG - 148-55 CY - UNITED STATES JC - IDM EM - 7611 RO - M:BDS PMID- 781114 LR - 840501 CU - 90 CA - SC863D no.316 1976 SO - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. ;:148-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 76239257 AU - Santa Rosa CA TI - Diagnosis of leptospirosis. pp. 143-7. LA - Eng MH - Abortion, Veterinary/diagnosis/immunology MH - Animal MH - Argentina MH - Brazil MH - Cattle MH - Female MH - Guinea Pigs MH - Hamsters MH - Human MH - Leptospirosis/*diagnosis/immunology/veterinary MH - Male MH - Pregnancy MH - Swine MH - Zoonoses/epidemiology PT - MONOGRAPH DA - 760925 TA - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. CY - UNITED STATES JC - IDM EM - 7611 PMID- 781113 CU - 90 CA - W1 PA443 no.316 1976 SO - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 76239255 AU - Stalheim OH TI - Chemotherapy and immunization in the control of leptospirosis in domestic animals. pp. 156-66. LA - Eng MH - Abortion, Veterinary/prevention & control MH - Animal MH - Bacterial Vaccines MH - Cattle MH - Cattle Diseases/prevention & control MH - Central America MH - Dihydrostreptomycin Sulfate/therapeutic use MH - Female MH - Guinea Pigs MH - Haplorhini MH - Immunization/*veterinary MH - Kidney Diseases/prevention & control/veterinary MH - Leptospira/immunology MH - Leptospirosis/drug therapy/prevention & control MH - Male MH - Pregnancy MH - South America MH - Swine MH - Swine Diseases/prevention & control PT - MONOGRAPH PT - REVIEW DA - 760925 TA - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. CY - UNITED STATES JC - IDM EM - 7611 RF - 34 PMID- 59772 CU - 95 CA - W1 PA443 no.316 1976 SO - In: VIII Inter-American Meeting on Foot-and-Mouth Disease an Zoonoses Control. Washington, Pan American Health Organization, 1976. W1 PA443 no.316 1976. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77057941 TI - [Jaundice and kidney failure] LA - Ger MH - Adult MH - Case Report MH - Human MH - Hypotension/etiology MH - Jaundice/*etiology MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications MH - Male PT - JOURNAL ARTICLE DA - 770129 DP - 1976 Sep 21 IS - 0369-8394 TA - Schweiz Rundsch Med Prax PG - 1176-8 CY - SWITZERLAND IP - 38 VI - 65 JC - SRM EM - 7703 PMID- 995873 CU - 84 NI - A TT - Ikterus und Nierenversagen SO - Schweiz Rundsch Med Prax 1976 Sep 21;65(38):1176-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 77101152 AU - Ryan TJ AU - Marshall RB TI - Isolation of a leptospire belonging to serogroup tarassovi [letter]. LA - Eng MH - Animal MH - Cattle MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Swine MH - Swine Diseases/*microbiology PT - LETTER DA - 770331 DP - 1976 SEP IS - 0048-0169 TA - N Z Vet J PG - 212-3 CY - NEW ZEALAND IP - 9 VI - 24 JC - OBZ EM - 7705 PMID- 1070624 CU - 91 SO - N Z Vet J 1976 SEP;24(9):212-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 77174872 AU - Brown GW AU - Lee CK AU - Huxsoll DL AU - Ng TS AU - Lim KJ AU - Wan HS AU - Eeran JD AU - Sannasey G TI - Leptospirosis in Malaysia: a common cause of short-term fever. LA - Eng MH - Fever/*etiology MH - Headache/etiology MH - Human MH - Jaundice/etiology MH - Leptospirosis/*complications/diagnosis MH - Malaysia MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 770630 DP - 1976 Sep IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 380-3 SB - M CY - THAILAND IP - 3 VI - 7 JC - UVN AA - Author EM - 7708 AB - A study of 1,437 unselected febrile patients in rural Malaysia yielded a diagnosis of leptospirosis in 86 (6.0%). The clinical syndrome was mild to moderate in all cases, jaundice was observed in only 2 (2.3%) and no deaths were documented. The diagnosis was not clinically obvious in most cases, and it is apparent that many infections must be going unnoticed at present. PMID- 1030842 SO - Southeast Asian J Trop Med Public Health 1976 Sep;7(3):380-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 77122527 AU - Sibalic S AU - Kurt A AU - Maric D AU - Lupi D AU - Mulic D AU - Jusufovic E TI - [Review of our patients with leptospirosis accompanied by jaundice syndrome] LA - Scr MH - English Abstract MH - Human MH - Jaundice/*etiology MH - Leptospirosis/*complications MH - Seasons MH - Syndrome PT - JOURNAL ARTICLE DA - 770415 DP - 1976 Sep-Oct IS - 0025-8083 TA - Med Arh PG - 323-6 CY - YUGOSLAVIA IP - 5 VI - 30 JC - LNY EM - 7706 PMID- 1018522 CU - 90 TT - Osvrt na nase bolesnike s leptospirozom pracene sindromom ikterusa EA - A SO - Med Arh 1976 Sep-Oct;30(5):323-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 77111716 AU - Watson AD AU - Wannan JS AU - Porges WL AU - Testoni FJ TI - Leptospiral agglutinins in dogs in Sydney. LA - Eng MH - Agglutinins/*analysis MH - Animal MH - Australia MH - Dog Diseases/*epidemiology MH - Dogs MH - Female MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 770315 DP - 1976 Sep IS - 0005-0423 TA - Aust Vet J PG - 425-6 SB - M CY - AUSTRALIA IP - 9 VI - 52 JC - 9IE AA - Author EM - 7705 AB - From June 1971 to June 1972, sera from 600 dogs in Sydney were tested for leptospiral agglutinins by a rapid slide agglutination method. The end-point titre was taken at 50 percent agglutination of the live organisms. Forty-one samples (6.8 percent) had a significant leptospiral titres (100 or greater) and 5 of these reacted to 2 serotypes. Thirty serums (5 percent) contained agglutinins against L. copenhageni, and 6 (1 percent) against L. pomona, while a few samples reacted against hardjo, tarassovi, australis, grippotyphosa or pyrogenes serotypes. No significant titres were found to L. canicola, L. hebdomadis, L. autumnalis or L. bataviae. PMID- 1016169 CU - 88 SO - Aust Vet J 1976 Sep;52(9):425-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 77111710 AU - Amatredjo A AU - Campbell RS AU - Trueman KF TI - A study of nephritis of beef cattle in North Queensland. LA - Eng MH - Agglutinins/analysis MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/epidemiology/*pathology MH - Female MH - Leptospira/immunology MH - Leptospirosis/pathology/*veterinary MH - Male MH - Nephritis/epidemiology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 770315 DP - 1976 Sep IS - 0005-0423 TA - Aust Vet J PG - 398-402 SB - M CY - AUSTRALIA IP - 9 VI - 52 JC - 9IE AA - Author EM - 7705 AB - The incidence of subclinical nephritis in beef cattle slaughtered at a Townsville abattoir during the period 1970-73 was 3.8 percent. A rising incidence coincided with the wet summer of 1973-74 reaching a peak of 8.2 percent thereafter in June 1974. All but 1 of 100 cases macroscopically identified as nephritis and studied histologically proved to be of interstitial type in which lymphocytic infiltration predominated. Follicular lymphoid hyperplasia was also a common feature. The exceptional case showed proliferative glomerulonephritis. Leptospires were isolated from 16 percent of cases cultured, and observed in 8 percent of specimens examined histologically. All of the 8 isolates subjected to serogrouping were L. pomona. Of the animals tested serologically against 2 serotypes 66.2 percent were positive to L. pomona (33.8 percent), L. hardjo (18.9 percent) or both (13.5 percent). The total incidence is significantly higher than in other random surveys carried out in the region. These findings suggest that Leptospira sp. are a major cause of bovine nephritis. Since other pathogens endemic in the area, for example, Babesia and Theileria sp., may be capable of causing nephritis in cattle an accurate assessment of the aetiology of that form of renal disease in north Queensland cannot yet be made. RO - M:LBR PMID- 1016164 LR - 790413 CU - 88 SO - Aust Vet J 1976 Sep;52(9):398-402 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 77040430 AU - Schutz J AU - Kleine HC AU - Lauf H TI - [Septic course of a leptospirosis due to serotype grippotyphosa (swamp fever)] LA - Ger MH - Acute Disease MH - Case Report MH - Electrocardiography MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*complications/diagnosis MH - Male MH - Middle Age MH - Phonocardiography MH - Septicemia/*etiology/microbiology PT - JOURNAL ARTICLE DA - 761230 DP - 1976 Sep 1 IS - 0044-2178 TA - Z Arztl Fortbild (Jena) PG - 939-43 SB - M CY - GERMANY, EAST IP - 18 VI - 70 JC - XS6 EM - 7702 PMID- 983161 CU - 84 TT - Septischer Verlauf einer Leptospirosis vom Serotyp grippotyphosa (Feldfieber) SO - Z Arztl Fortbild (Jena) 1976 Sep 1;70(18):939-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 77006426 AU - Thigpen JE AU - Thierry VL AU - Gupta BN TI - Primary isolation of Mycobacterium avium complex-serotype 6 on blood agar. LA - Eng MH - Agar MH - Animal MH - Blood MH - Female MH - Mycobacterium/*isolation & purification MH - Mycobacterium avium/classification/*isolation & purification MH - Mycobacterium Infections/microbiology/*veterinary MH - *Opossums MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 761203 DP - 1976 Sep IS - 0095-1137 TA - J Clin Microbiol PG - 266-9 SB - M CY - UNITED STATES IP - 3 VI - 4 JC - HSH AA - Author EM - 7701 AB - Mycobacterium avium complex-serotype 6 was isolated in pure culture on blood agar plates from inocula taken from the heart blood, lungs, liver, kidneys, and spleen of a naturally infected captive female opossum (Didelphis marsupialis virginiana). Repeat cultures from stored tissues and transfer of colonies from original blood agar plates revealed that the mycobacterium grew on tryptose, brilliant green, eosin-methylene blue. Sabouraud glucose, and mycobiotic agar plates and in Fletcher leptospira medium. The cultural, biochemical, and serological characteristics of the test isolate were compared with other mycobacteria. This is the first report to describe the primary isolation of a serotype from the M. avium complex from an animal species on blood agar or in Fletcher broth. In addition, this is the second documented report describing the isolation and identification of a mycobacterial species from the American opossum. PMID- 972192 CU - 90 SO - J Clin Microbiol 1976 Sep;4(3):266-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 77005267 AU - Adler B AU - Faine S TI - Susceptibility of mice treated with cyclophosphamide to lethal infection with Leptospira interrogans Serovar pomona. LA - Eng MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Antibody Formation/*drug effects MH - Blood/microbiology MH - Cyclophosphamide/*pharmacology MH - Female MH - Immunity, Active MH - Immunity, Maternally-Acquired MH - Immunization, Passive MH - Leptospira interrogans/growth & development/*immunology MH - Male MH - Mice MH - Mice, Inbred BALB C MH - Spleen/immunology MH - Time Factors MH - Weil's Disease/*immunology/prevention & control PT - JOURNAL ARTICLE DA - 761201 DP - 1976 Sep IS - 0019-9567 TA - Infect Immun PG - 703-8 SB - M CY - UNITED STATES IP - 3 VI - 14 JC - GO7 AA - Author EM - 7701 AB - Mice not normally susceptible to infection with Leptospira interrogans serovar pomona were rendered susceptible to lethal infections by treatment with a single dose of 300 mg of cyclophosphamide (Cy) per kg administered optimally from 4 days before to 1 day after infection. Cy- treated mice with either passively or actively acquired antibody were protected from death. Blood levels of leptospires in infected untreated and in Cy-treated mice remained similar until 2 days after infection, when untreated mice cleared the leptospires. Soon afterwards, opsonizing and agglutinating antibody appeared. Cy-treated mice given spleen cells from other normal or specifically immune mice were protected from infection. An important factor in the natural resistance of mice to leptospiral infection appears to be their capacity to produce circulating antibody within 48 to 72 h. Applications are suggested for this animal model in vaccination and protection studies. PMID- 965093 CU - 90 SO - Infect Immun 1976 Sep;14(3):703-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76266756 AU - Ellner JJ AU - Bennett JE TI - Chronic meningitis. LA - Eng MH - Actinomycosis/diagnosis MH - Adolescence MH - Adult MH - Behcet's Syndrome/diagnosis MH - Blastomycosis/diagnosis MH - Brain Neoplasms/diagnosis MH - Brucellosis/diagnosis MH - Candidiasis/diagnosis MH - Case Report MH - Chronic Disease MH - Coccidioidomycosis/*diagnosis MH - Cryptococcosis/*diagnosis MH - Cysticercosis/diagnosis MH - Epidermal Cyst/diagnosis MH - Female MH - Histoplasmosis/diagnosis MH - Human MH - Leptospirosis/diagnosis MH - Male MH - Meningitis/*diagnosis MH - Middle Age MH - Nocardia Infections/diagnosis MH - Sarcoidosis/diagnosis MH - Toxoplasmosis/diagnosis MH - Tuberculosis, Meningeal/*diagnosis MH - Uveomeningoencephalitic Syndrome/diagnosis PT - JOURNAL ARTICLE DA - 761101 DP - 1976 Sep IS - 0025-7974 TA - Medicine (Baltimore) PG - 341-69 SB - A SB - M CY - UNITED STATES IP - 5 VI - 55 JC - MNY EM - 7612 PMID- 957996 CU - 90 SO - Medicine (Baltimore) 1976 Sep;55(5):341-69 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 78120896 AU - Sankale M AU - Sow AM AU - Ruscher H AU - Sarrat H TI - [Leptospirosis in a Dakar hospital: results of a new survey] LA - Fre MH - Adult MH - Animal MH - Antigens, Bacterial/analysis MH - Case Report MH - English Abstract MH - Female MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Rodentia MH - Senegal MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 780426 DP - 1976 Sep TA - Afr J Med Med Sci PG - 213-20 SB - M CY - ENGLAND IP - 3 VI - 5 JC - 29G AA - Author EM - 7806 AB - The incidence of leptospirosis in West Africa is still almost unknown. Doubtful or positive serological tests were found in approx. 35% of the patients admitted to the hospital, among which leptospirosis could clinically or biologically be suspected. This rather high proportion reflects the frequency of recent or past contacts with leptospira antigen. It is in agreement with the high infestation prevalence observed among several domestic or wild animals, besides small rodents. On the countrary, it should be noted that the leptospirosis-illness, at least in its pure form, with its characteristic hepatic, renal and neurological signs, is seldom seen. Seven typical cases only (among which five at the hosptical Le Dantec) have been diagnosed in Dakar during these last 6 years. Even taking into account that the proportion of atypical, fruste or undiagnosed forms is not negligible, leptospirosis does not appear to be a major medical problem in Senegal. PMID- 829732 CU - 91 TT - La leptospirose en milieu hospitalier a Dakar. Resultats d'une nouvelle enquete. EA - A SO - Afr J Med Med Sci 1976 Sep;5(3):213-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 77047192 AU - Klanica J AU - Sramkova L AU - Cervova H TI - [Immunofluorescent technique in serology of leptospiroses. II. Demonstration of specific IgM antibodies in acute leptospiroses (author's transl)] LA - Cze MH - Adolescence MH - Adult MH - Antibodies, Bacterial/analysis MH - Antibody Formation MH - Child MH - English Abstract MH - Human MH - IgM/*isolation & purification MH - Leptospirosis/*immunology MH - Middle Age PT - JOURNAL ARTICLE DA - 770129 DP - 1976 Sep IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 280-6 CY - CZECHOSLOVAKIA IP - 5 VI - 25 JC - CSH EM - 7703 PMID- 136308 CU - 92 TT - Imunofluorescencni technika v serologii leptospiroz II. Prukaz specifickych IgM protilatek u akutnich leptospiroz EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1976 Sep;25(5):280-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 77047190 AU - Sebek Z AU - Odehnal P TI - [First case of leptospirosis caused by serotype from the serogroup autumnalis in CSR (author's transl)] LA - Cze MH - Adult MH - Antibodies, Bacterial MH - Antibody Formation MH - Case Report MH - Czechoslovakia MH - English Abstract MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*immunology MH - Male MH - Serotyping PT - JOURNAL ARTICLE DA - 770129 DP - 1976 Sep IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 269-73 CY - CZECHOSLOVAKIA IP - 5 VI - 25 JC - CSH EM - 7703 PMID- 136306 CU - 92 TT - Prvy pripad leptospirozy vyvolane serotypem ze serologicke skupiny autumnalis v CSR EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1976 Sep;25(5):269-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 77030577 AU - Kaiser GE AU - Doetsch RN TI - The effects of alkalinity and hypertonicity on the morphology and motility of Leptospira interrogans (biflexa) strain B16. LA - Eng MH - *Culture Media MH - Deuterium/pharmacology MH - Edetic Acid/pharmacology MH - Hydrogen-Ion Concentration MH - Hypertonic Solutions MH - Leptospira interrogans/*cytology MH - Movement MH - Sucrose PT - JOURNAL ARTICLE DA - 761223 DP - 1976 Sep IS - 0022-1287 TA - J Gen Microbiol PG - 25-33 SB - M CY - ENGLAND IP - 1 VI - 96 JC - I87 AA - Author EM - 7702 AB - Effects of alkalinity and hypertonicity on the motile behaviour of Leptospira interrogans (biflexa) B16 were observed, quantified, and compared with effects previously shown by similar factors on the motility of eubacteria. Leptospira interrogans tolerated relatively high concentrations of hydroxide ions. Motility similar to that in controls was observed at pH values up to 9-8; but at pH 10-0 motility declined sharply with time of exposure, and there was structural alteration, visible as a blebbing of the cell envelope. Unlike the behaviour of eubacteria, immobilization of L. interrogans induced by hydroxide ions could not be reversed by lowering the pH. It is suggested that by restricting entry of hydroxide ions, the cell envelope protects its motility apparatus from adverse effects. Leptospira interrogans was completely immobilized in 0-5 M and 1-0 M- sucrose solutions. Unlike the eubacteria, leptospires were incapable of spontaneous reversion to motile forms and resumption of motility was dependent on both concentration and time of exposure to sucrose. Deuterium oxide did not affect movement, suggesting that even though leptospire endoflagella and the exoflagella of eubacteria are analogous, the motile behaviour of L. interrogans is significantly different from that of eubacteria. PMID- 10348 CU - 94 SO - J Gen Microbiol 1976 Sep;96(1):25-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 77055890 AU - Adler B AU - Bragger JM TI - Leptospiral infections in humans [letter]. LA - Eng MH - Australia MH - Human MH - Immunotherapy MH - Leptospirosis/*epidemiology/prevention & control MH - New Zealand PT - LETTER DA - 770125 DP - 1976 Aug 28 IS - 0025-729X TA - Med J Aust PG - 357 SB - M CY - AUSTRALIA IP - 9 VI - 2 JC - M26 EM - 7703 PMID- 995023 CU - 91 SO - Med J Aust 1976 Aug 28;2(9):357 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 77077731 AU - Ryan TJ AU - Marshall RB AU - Blackmore DK TI - Leptospira interrogans serovar tarassovi in New Zealand [letter]. LA - Eng MH - Animal MH - Leptospira interrogans/*isolation & purification MH - Swine MH - Swine Diseases/*microbiology MH - Weil's Disease/microbiology/*veterinary MH - Zoonoses PT - LETTER DA - 770216 DP - 1976 Aug 25 IS - 0028-8446 TA - N Z Med J PG - 171 SB - M CY - NEW ZEALAND IP - 570 VI - 84 JC - OBQ EM - 7704 PMID- 1069932 CU - 91 SO - N Z Med J 1976 Aug 25;84(570):171 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 76215006 AU - Willcox RR TI - The epidemiology of the spirochetoses. A worldwide view. pp. 133-55. LA - Eng MH - Animal MH - Borrelia Infections/epidemiology/veterinary MH - Disease Reservoirs MH - Haplorhini MH - Human MH - Leptospirosis/epidemiology/veterinary MH - Mice MH - Monkey Diseases/epidemiology MH - Pinta/epidemiology MH - Rabbits MH - Rats MH - Relapsing Fever/epidemiology MH - Rodent Diseases/epidemiology MH - Spirochaeta/classification MH - Spirochaetales/classification MH - Spirochaetales Infections/*epidemiology MH - Syphilis/epidemiology MH - Treponemal Infections/epidemiology/veterinary MH - Yaws/epidemiology PT - MONOGRAPH PT - REVIEW DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 RF - 62 PMID- 819515 CU - 91 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 76215010 AU - Stoenner HG TI - Treatment and control of leptospirosis. pp. 375-88. LA - Eng MH - Animal MH - Bacterial Vaccines MH - Cattle MH - Cattle Diseases/drug therapy/prevention & control MH - Dog Diseases/drug therapy/prevention & control MH - Dogs MH - Human MH - Leptospira/immunology MH - Leptospirosis/*drug therapy/prevention & control/veterinary MH - Penicillins/therapeutic use MH - Swine MH - Swine Diseases/prevention & control MH - Tetracyclines/therapeutic use PT - MONOGRAPH PT - REVIEW DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 RF - 41 PMID- 777571 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 76215003 AU - Smith H TI - The determinants of microbial pathogenicity in relation to spirochetal disease. pp. 235-47. LA - Eng MH - Animal MH - Antibodies, Bacterial MH - Antibody Formation MH - Bacteria/pathogenicity MH - Blood Bactericidal Activity MH - Borrelia/pathogenicity MH - Cell Division MH - Guinea Pigs MH - Hamsters MH - Human MH - Immunity, Cellular MH - Leptospira/metabolism/pathogenicity MH - Phagocytosis MH - Rabbits MH - Spirochaetales/growth & development/*pathogenicity MH - Spirochaetales Infections/immunology MH - Toxins/biosynthesis MH - Treponema pallidum/pathogenicity MH - Virulence PT - MONOGRAPH PT - REVIEW DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 RF - 28 PMID- 777566 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 76215002 AU - Murray RG TI - Some perspectives for thinking about spirochaetal structure. pp. 1-5. LA - Eng MH - Borrelia/ultrastructure MH - Cell Nucleus/ultrastructure MH - Cell Wall/ultrastructure MH - Flagella/ultrastructure MH - Leptospira/ultrastructure MH - Spirochaetales/*ultrastructure MH - Treponema/ultrastructure PT - MONOGRAPH DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 PMID- 777565 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 76214996 AU - Hanson LE TI - Pathogenesis of leptospirosis. pp. 295-306. LA - Eng MH - Abortion, Veterinary MH - Anemia, Hemolytic/veterinary MH - Animal MH - Cattle MH - Cattle Diseases MH - Dog Diseases MH - Dogs MH - Female MH - Hemorrhage/veterinary MH - Horse Diseases MH - Horses MH - Human MH - Kidney/microbiology MH - Lactation Disorders/veterinary MH - *Leptospirosis/immunology/microbiology/veterinary MH - Nephritis, Interstitial/veterinary MH - Pregnancy MH - Sheep MH - Sheep Diseases MH - Swine MH - Swine Diseases PT - MONOGRAPH DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 PMID- 777561 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 76214995 AU - Ellinghausen HC Jr TI - Nutrition of leptospires in bovine albumin polysorbate medium. pp. 65- 85. LA - Eng MH - Ammonium Chloride/metabolism MH - Comparative Study MH - Culture Media MH - Human MH - Leptospira/*growth & development MH - Leptospira canicola/growth & development MH - Leptospira interrogans/growth & development MH - Polysorbates MH - Serum Albumin, Bovine/metabolism MH - Thiamine/metabolism MH - Time Factors MH - Vitamin B 12/metabolism PT - MONOGRAPH DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 PMID- 777560 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 76214994 AU - Ritchie AE TI - Morphology of leptospires. pp. 19-37. LA - Eng MH - Cell Membrane/ultrastructure MH - Cell Nucleus/ultrastructure MH - Cytoplasmic Granules/ultrastructure MH - Leptospira/*ultrastructure MH - Leptospira interrogans/ultrastructure PT - MONOGRAPH DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 PMID- 777559 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 76214992 AU - Shotts EB Jr TI - Laboratory diagnosis of leptospirosis. pp. 209-23. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial MH - Blood/microbiology MH - Cerebrospinal Fluid/microbiology MH - Chickens MH - Fluorescent Antibody Technique MH - Gerbillinae MH - Guinea Pigs MH - Hamsters MH - Hemagglutination Tests MH - Human MH - Leptospira/growth & development/immunology/isolation & purification MH - Leptospirosis/*diagnosis/immunology/microbiology MH - Methods MH - Urine/microbiology PT - MONOGRAPH DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 PMID- 777557 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 76214989 AU - Alexander AD TI - Immunity in leptospirosis. pp. 339-49. LA - Eng MH - Animal MH - Antigens, Bacterial MH - Bacterial Vaccines MH - Cross Reactions MH - Human MH - Immunity, Active MH - Immunization MH - Immunization, Passive MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology PT - MONOGRAPH PT - REVIEW DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 RF - 70 PMID- 777556 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 76214987 AU - Kaufmann AF TI - Epidemiologic trends of leptospirosis in the United States, 1965-1974. pp. 177-89. LA - Eng MH - Adult MH - Animal MH - Disease Reservoirs MH - Dog Diseases/transmission MH - Dogs MH - Human MH - Leptospira canicola MH - Leptospira interrogans MH - Leptospirosis/*epidemiology/transmission/veterinary MH - Male MH - Rats MH - Rodent Diseases/transmission MH - Soil Microbiology MH - United States MH - Water Microbiology PT - MONOGRAPH DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 PMID- 777554 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 76214983 AU - Johnson RC TI - Comparative spirochete physiology and cellular composition. pp. 39-48. LA - Eng MH - Amino Acids/biosynthesis MH - Borrelia/metabolism MH - Cell Wall/metabolism MH - Comparative Study MH - Culture Media MH - Endotoxins/biosynthesis MH - Fatty Acids/metabolism MH - Leptospira/metabolism MH - Oxygen Consumption MH - Phospholipids/metabolism MH - Spirochaeta/metabolism MH - Spirochaetales/*metabolism MH - Support, U.S. Gov't, Non-P.H.S. MH - Support, U.S. Gov't, P.H.S. MH - Treponema/metabolism MH - Urea/metabolism PT - MONOGRAPH DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 PMID- 777550 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 76214982 AU - Turner LH TI - Classification of spirochaetes in general and of the genus Leptospira in particular. pp. 95-106. LA - Eng MH - Borrelia/classification MH - Leptospira/*classification/immunology MH - Leptospira canicola/classification/immunology MH - Leptospira interrogans/classification/immunology MH - Spirochaeta/classification MH - Spirochaetales/*classification MH - Treponema/classification PT - MONOGRAPH PT - REVIEW DA - 760823 TA - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. CY - UNITED STATES JC - IDM EM - 7610 RF - 30 PMID- 777549 CU - 90 CA - QW 155 S989 1975b SO - In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b. ;: ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76233264 AU - Derham RL AU - Owens GG AU - Wooldridge MA TI - Leptospirosis as a cause of erythema nodosum. LA - Eng MH - Case Report MH - Child MH - Erythema Nodosum/*etiology MH - Female MH - Human MH - Leptospira canicola/isolation & purification MH - Leptospirosis/*complications/microbiology PT - JOURNAL ARTICLE DA - 761001 DP - 1976 Aug 14 IS - 0007-1447 TA - Br Med J PG - 403-4 SB - A SB - M CY - ENGLAND IP - 6032 VI - 2 JC - B4W EM - 7611 PMID- 947446 SO - Br Med J 1976 Aug 14;2(6032):403-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 77101139 AU - Hodges RT AU - Millar KR AU - Revfeim KJ TI - The effects of Leptospira serotype pomona in sheep of different haemoglobin types. LA - Eng MH - Animal MH - Hematocrit MH - Hemoglobin C/analysis MH - Hemoglobins/*analysis MH - Leptospirosis/blood/*veterinary MH - Male MH - Sheep MH - Sheep Diseases/*blood PT - JOURNAL ARTICLE DA - 770331 DP - 1976 Aug IS - 0048-0169 TA - N Z Vet J PG - 163-6 CY - NEW ZEALAND IP - 8 VI - 24 JC - OBZ EM - 7705 PMID- 1070613 CU - 88 SO - N Z Vet J 1976 Aug;24(8):163-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77197219 AU - Il'inskii EV AU - Rodionov VI TI - [Effect of vaccination on the reproductive function of animals] LA - Rus MH - Agglutinins/isolation & purification MH - Animal MH - Anthrax/prevention & control/veterinary MH - Bacterial Vaccines/*pharmacology MH - Cattle MH - Cattle Diseases/prevention & control MH - Female MH - *Fertilization MH - Foot-and-Mouth Disease/prevention & control MH - Leptospirosis/prevention & control/veterinary MH - Male MH - Pregnancy MH - *Sperm Motility MH - Spermatozoa/immunology MH - Viral Vaccines/*pharmacology PT - JOURNAL ARTICLE DA - 770718 DP - 1976 Aug IS - 0042-4846 TA - Veterinariia PG - 78-9 CY - USSR IP - 8 JC - XCC EM - 7709 PMID- 1027215 TT - Vosproizvoditel'naia funktsiia pri vaktsinatsii zhivotnykh SO - Veterinariia 1976 Aug;(8):78-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 76246809 AU - Hill WK AU - Weenink-Van Loon CD TI - [Review of the incidence of antibodies to various serological groups of the species Leptospira interrogans in a number of farm animals in the Netherlands (author's transl)] LA - Dut MH - Abortion, Septic/veterinary MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/immunology MH - Dog Diseases/immunology MH - Dogs MH - English Abstract MH - Female MH - Horse Diseases/immunology MH - Horses MH - Leptospira interrogans/*immunology MH - Leptospirosis/classification/immunology/*veterinary MH - Netherlands MH - Pregnancy MH - Serotyping MH - Swine MH - Swine Diseases/immunology MH - Weil's Disease/veterinary PT - JOURNAL ARTICLE DA - 761002 DP - 1976 Aug 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 835-48 SB - M CY - NETHERLANDS IP - 15 VI - 101 JC - VRY AA - Author EM - 7611 AB - Report on the results of serological studies on the species Leptospira interrogans in cattle (19,607), swine (6,348), dogs (182) and horses (88) from the Netherlands during the period from 1969 to 1974. Living cultures of the serotypes of pomona, icterohaemorrhagiae, canicola, guidae (Tarassovi serological group), grippotyphosa and sejroe were used as antigen in the micro-agglutination test. The numerical findings showed that antibodies to serotypes of the species Leptospira interrogans were present in 7.67 per cent of the cattle, 22.21 per cent of the pigs, 36.81 per cent of the dogs and 92.05 per cent of the horses studied. Infection with the serotypes of icterohaemorrhagiae and grippotyphosa was most common in cattle and horses, icterohaemorrhagiae and tarassovi were most common in swine and icterohaemorrhagiae and canicola were most common in dogs. The presence of pomona is not a factor in the Netherlands. In view of statistical findings, grippotyphosa infections in cattle may be assumed to result in abortion. PMID- 986091 CU - 85 TT - Een overzicht over het voorkomen van anti-lichamen tegen verschillende serogroepen van het species leptospira interrogans bij enkele huisdiersoorten in nederland EA - A SO - Tijdschr Diergeneeskd 1976 Aug 1;101(15):835-48 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 77041075 AU - Hergt R TI - [Meaning of serotype Patoc (biflexa complex) for the diagnosis of leptospirosis by microscopic agglutination test (author's transl)] LA - Ger MH - Agglutination Tests/methods MH - Diagnostic Errors MH - English Abstract MH - Human MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis MH - Serotyping PT - JOURNAL ARTICLE DA - 761230 DP - 1976 Aug IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 506-11 SB - M CY - GERMANY, WEST IP - 4 VI - 235 JC - Y52 AA - Author EM - 7702 AB - Agglutination with serotype patoc (Patoc 1) was found in 72 of 125 cases of leptospirosis. Patoc-agglutination occured frequently in leptospirosis icterohaemorrhagiae, less frequently in leptospirosis grippotyphosa and rarely in leptospirosis tarassovi. 53 cases of leptospirosis were not diagnosed when using Patoc 1 as single antigen. So we cannot recommend to use serotype patoc as the sole antigen for microscopic agglutination test. We observed 1 case in which the reaction with Patoc 1 happened earlier than the reaction with the pathogen serotypes. For this reason the battery of antigens for carrying out microscopic agglutination test should include serotype patoc, too. PMID- 983536 TT - Die Bedeutung des Serotyps patoc (biflexa complex) fur die Leptospirose- Diagnostik mit der Agglutinations-Lysis-Reaktion EA - A SO - Zentralbl Bakteriol [Orig A] 1976 Aug;235(4):506-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 76276362 AU - David R AU - Barkay S TI - Anterior uveitis and leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Case Report MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/*complications/immunology MH - Male MH - Serotyping MH - Uveitis/*etiology PT - JOURNAL ARTICLE DA - 761029 DP - 1976 Aug IS - 0003-4886 TA - Ann Ophthalmol PG - 958-62 SB - M CY - UNITED STATES IP - 8 VI - 8 JC - 5PA AA - Author EM - 7612 AB - Seven patients with anterior uveitis due to leptospirosis are presented. The diagnosis was based upon serologic tests and exclusion of other etiologic possibilities. Six patients came from a well-known endemic area of leptospirosis during the time of epidemics and one case came from an area which was not known to be endemic at the time. In 5 patients the uveitis was bilateral. The disease was mild in all but 2 patents who needed systemic administration of steroids. The posterior part of the eye was not involved in any of the cases. PMID- 962269 SO - Ann Ophthalmol 1976 Aug;8(8):958-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 77035094 AU - Marshall RB AU - Manktelow BW AU - Ryan TO AU - Hathaway SC TI - Leptospira interrogans serovar balcanica from a possum [letter]. LA - Eng MH - Animal MH - Hamsters MH - Leptospira interrogans/*isolation & purification MH - Marsupialia/*microbiology MH - Meningitis/etiology MH - New Zealand MH - Weil's Disease/complications PT - LETTER DA - 761223 DP - 1976 Jul 28 IS - 0028-8446 TA - N Z Med J PG - 74-5 SB - M CY - NEW ZEALAND IP - 568 VI - 84 JC - OBQ EM - 7702 PMID- 1068389 CU - 91 SO - N Z Med J 1976 Jul 28;84(568):74-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 77047441 AU - Tinelli R AU - Gabay J TI - [Polysaccharide antigen from the leptospira L. biflefa patoc] LA - Fre MH - Antigens, Bacterial/analysis/*isolation & purification MH - Cross Reactions MH - English Abstract MH - Leptospira/*immunology MH - Polysaccharides, Bacterial/*immunology MH - Serotyping MH - Structure-Activity Relationship PT - JOURNAL ARTICLE DA - 770129 DP - 1976 Jul 12 IS - 0567-655X TA - C R Acad Sci Hebd Seances Acad Sci D PG - 215-8 SB - M CY - FRANCE IP - 2 VI - 283 JC - C9C AA - Author EM - 7703 AB - We have extracted from L. biflexa patoc (using sodium desoxycholate) a fraction F containing 65% of polysaccharide, reacting in hemagglutination and ring-test with sera prepared against 8 different serogroups. PMID- 825265 CU - 91 TT - Antigene polosidique extrait du leptospire L. biflexa patoc EA - A SO - C R Acad Sci Hebd Seances Acad Sci D 1976 Jul 12;283(2):215-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 77133626 AU - Nicolescu M AU - Straton A AU - Alamita I TI - Unusual and new Leptospira hebdomadis serotypes isolated from wild small rodents in Romania. LA - Eng MH - Animal MH - Leptospira/*classification MH - Rodentia/*microbiology MH - Romania MH - Serotyping PT - JOURNAL ARTICLE DA - 770425 DP - 1976 Jul IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 203-11 CY - ROMANIA IP - 3 VI - 35 JC - 8EM EM - 7706 PMID- 1021044 SO - Arch Roum Pathol Exp Microbiol 1976 Jul;35(3):203-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 77057877 AU - Chambers RA TI - The early diagnosis and investigation of the meningitides. LA - Eng MH - Acute Disease MH - Bacteria/isolation & purification MH - Candida/isolation & purification MH - Candidiasis/complications MH - Cerebrospinal Fluid/analysis/microbiology MH - Fever MH - Human MH - Leptospira/isolation & purification MH - Meningitis/*diagnosis/etiology/immunology MH - Meningitis, Meningococcal/diagnosis MH - Meningitis, Viral/diagnosis MH - Tuberculosis, Meningeal/diagnosis MH - Vomiting PT - JOURNAL ARTICLE DA - 770129 DP - 1976 Jul IS - 0032-6518 TA - Practitioner PG - 82-90 SB - M CY - ENGLAND IP - 1297 VI - 217 JC - PHQ EM - 7703 PMID- 995829 SO - Practitioner 1976 Jul;217(1297):82-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76265928 AU - Bryson DG AU - Ellis WA TI - Leptospirosis in a British domestic cat. LA - Eng MH - Animal MH - Case Report MH - *Cat Diseases MH - Cats MH - Female MH - Great Britain MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 761029 DP - 1976 Jul IS - 0022-4510 TA - J Small Anim Pract PG - 459-65 CY - ENGLAND IP - 7 VI - 17 JC - K4N EM - 7612 PMID- 957622 SO - J Small Anim Pract 1976 Jul;17(7):459-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 76265129 AU - Ramachandran S AU - Rajapakse CN AU - Perera MV AU - Yoganathan M TI - Patterns of acute renal failure in leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Anuria/etiology MH - Bilirubin/blood MH - Blood Urea Nitrogen MH - Child MH - Child, Preschool MH - Human MH - Hypotension/etiology MH - Jaundice/etiology MH - Kidney/pathology MH - Kidney Failure, Acute/blood/*etiology/pathology MH - Leptospirosis/*complications MH - Middle Age MH - Oliguria/etiology MH - Potassium/blood MH - Sodium/blood PT - JOURNAL ARTICLE DA - 761029 DP - 1976 Jul IS - 0022-5304 TA - J Trop Med Hyg PG - 158-60 SB - M CY - ENGLAND IP - 7 VI - 79 JC - KAV AA - Author EM - 7612 AB - The renal profile was studied in 61 patients having leptospirosis. Leptospira-induced acute renal failure conformed to one of two distinct clinical patterns, either oliguric on non-oliguric renal failure. The prognosis was excellent in the latter variety of renal failure and mortality was confined to patients with oliguric renal failure, where severe glomerular and widespread tubulo-interstitial lesions were invariably present. These patients had unfavourable prognostic features during life, such as prolonged oliguria and anuria, absence of a diruetic phase, persistent elevations in BUN and persistently low urea excretion. The prognostic significance of the age of the patients, hypotension and jaundice in relation to the occurrence and type of acute renal failure have been discussed. Retrospective observations indicate that both a vasculotoxic or haemorrhagic state and oliguric acute renal failure are important causes for mortality in human leptospiral infections. PMID- 957464 CU - 90 SO - J Trop Med Hyg 1976 Jul;79(7):158-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76233627 AU - Kingscote B AU - Tittiger F TI - Serological survey of dogs from Toronto for leptospiral antibodies. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Dogs/*immunology MH - Female MH - Leptospira/*immunology MH - Male MH - Ontario PT - JOURNAL ARTICLE DA - 761002 DP - 1976 Jul IS - 0008-5286 TA - Can Vet J PG - 192-3 CY - CANADA IP - 7 VI - 17 JC - CLS EM - 7611 PMID- 949675 SO - Can Vet J 1976 Jul;17(7):192-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 77014923 AU - Prodrom I AU - Popa O AU - Raileanu I AU - Radu T AU - Voiculescu G AU - Cretu G TI - [Diagnostic value of blood fibrinogen in leptospirosis] LA - Rum MH - English Abstract MH - *Fibrinogen/analysis MH - Human MH - Leptospirosis/blood/*diagnosis PT - JOURNAL ARTICLE DA - 761201 DP - 1976 Jul-Sep IS - 0376-4494 TA - Rev Ig [Bacteriol] PG - 181-4 SB - M CY - ROMANIA IP - 3 VI - 21 JC - S7C AA - Author EM - 7701 AB - A study was carried out on the value of the presumptive diagnosis of fibrinogenemia in the uncharacteristic forms of leptospirosis, during the first eight days of the disease, in 42 cases, as compared to that of erythrocyte sedimentation rate. The results of fibrinogenemia determinations were more suggestive of the diagnosis at the beginning of the disease. PMID- 135335 CU - 92 TT - Valoarea diagnostica a fibrinogenemiei in leptospiroza EA - A SO - Rev Ig [Bacteriol] 1976 Jul-Sep;21(3):181-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77010232 AU - Owen D TI - Some parasites and other organisms of wild rodents in the vicinity of an SPF unit. LA - Eng MH - Animal MH - Antibodies, Bacterial MH - *Germ-Free Life MH - *Housing, Animal MH - Leptospira/immunology MH - Mice/microbiology/*parasitology MH - Mycoplasma/isolation & purification MH - Rats/microbiology/*parasitology MH - *Specific Pathogen-Free Organisms PT - JOURNAL ARTICLE DA - 761121 DP - 1976 Jul IS - 0023-6772 TA - Lab Anim PG - 271-8 SB - M CY - ENGLAND IP - 3 VI - 10 JC - KYQ AA - Author EM - 7701 AB - 80 Rattus norvegicus and 63 Mus musculus caught near the Laboratory Animals Centre, were examined for parasites and other organisms: 32 parasite species were found and 2 species of Mycoplasma. A small number of individuals were tested and found positive serologically for species of Leptospira. PMID- 135126 CU - 92 SO - Lab Anim 1976 Jul;10(3):271-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 77062461 AU - Colding H AU - Johansen KS AU - Bentzon MW TI - Decreased delayed hypersensitivity to tuberculin demonstrated in experimental leptospirosis in guinea pigs. LA - Eng MH - Animal MH - Guinea Pigs MH - *Hypersensitivity, Delayed MH - Leptospirosis/*immunology MH - Male MH - Pilot Projects MH - *Tuberculin Test PT - JOURNAL ARTICLE DA - 770129 DP - 1976 Jun IS - 0304-1328 TA - Acta Pathol Microbiol Scand [C] PG - 255-60 SB - M CY - DENMARK IP - 3 VI - 84 JC - 1O3 AA - Author EM - 7703 AB - Skin reactivity to tuberculin has been studied during the course of experimental leptospirosis in guinea pigs. A depression of the delayed hypersensitivity to tuberculin was demonstrated in the infected animals. The depression was most pronounced when icterus had developed. The depression was not correlated with the amount of infectious units administered or with the demonstration of live leptospirae in the peritoneal cavity. In the infected animals there was no correlation between the initial and the final skin tests which is in contrast to findings in the control group. PMID- 998265 SO - Acta Pathol Microbiol Scand [C] 1976 Jun;84(3):255-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 77028003 AU - Ryu E TI - An international survey of leptospiral agglutinin of dogs by RMAT. LA - Eng MH - Agglutination Tests MH - Animal MH - Comparative Study MH - Dogs MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 761230 DP - 1976 Jun TA - Int J Zoonoses PG - 33-60 SB - M CY - TAIWAN IP - 1 VI - 3 JC - GTK AA - Author EM - 7702 AB - FRom 1970 through 1973, the author used RMAT to examine the canine leptospiral antibodies against 10 serotypes in 12,374 attended dogs, 1,855 stray dogs and 480 house dogs in 24 countries. Among the 10 serotypes, L. icterohaemorrhagiae and L. canicola were the most prevalent. Positive rates were in the following order: Peru 26.3%, Chile 18.4%, Turkey 17.4%, Austria 16.0%, Korea 15.0%, Cina (Taiwan) 11.4%, Japan 9.8%, Brazil 7.7%, United States 5.5%, United Kingdom 4.5%, Italy 3.5%, Germany 2.0%, and Canada 0.4%. Negative results were obtained in Australia, Dominica, Ecuador, Ethiopia, Fiji, Indonesia, Iran, Malta, Philippines, Sweden and Thailand. Positive rates on different continents were: South America 11.1%, Asia 10.1%, Europe 3.4%, North America 2.4%, Oceania and Africa (Ethiopia) 0%. Negative results were obtained against either L. icterohaemorrhagiae or L. canicola in samples from most tropical countries. Lower positive rates were seen during summer in Korea and Japan. Positive reactors were detected against other serotypes, viz., L. grippotyphosa, L. australis A, L. pyrogenes, L. bataviae, L. autumnalis, L. hebdomadis and L. javanica. Sex, physical condition and vaccination status as factors in the presence of antibodies were reviewed. PMID- 977231 CU - 89 SO - Int J Zoonoses 1976 Jun;3(1):33-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77021220 AU - Holroyd RG AU - Smith PC TI - The effect of Leptospira hardjo vaccine in a northern Queensland beef herd. LA - Eng MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/*prevention & control MH - Female MH - Lactation MH - Lactation Disorders/veterinary MH - Leptospirosis/prevention & control/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/prevention & control/*veterinary MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 761121 DP - 1976 Jun IS - 0005-0423 TA - Aust Vet J PG - 258-60 SB - M CY - AUSTRALIA IP - 6 VI - 52 JC - 9IE AA - Author EM - 7701 AB - In a northern Queensland beef herd where there was serological evidence of L. hardjo infection, lactation failure or wastage between pregnancy diagnosis and branding was 11.9% in animals vaccinated with a single dose of a L. hardjo vaccine and 19.4% in unvaccinated controls. This difference was statistically significant (P less than 0.05). Vaccination caused a significant (P less than 0.05) reduction in rate of lactation failure in heifers but not in other classes of cows. PMID- 971143 CU - 90 SO - Aust Vet J 1976 Jun;52(6):258-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76247839 AU - Stepanenko PP AU - Liubashenko SIa AU - Netsepliaev SV AU - Iaichuk VR AU - Seregin IG TI - [Immunobiological reactivity in swine infected with radioactive phosphorus-labeled Leptospira] LA - Rus MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Specificity MH - *Antigen-Antibody Reactions MH - Leptospirosis/*immunology MH - Phosphorus Radioisotopes MH - Swine MH - Swine Diseases/*immunology MH - Time Factors PT - JOURNAL ARTICLE DA - 761001 DP - 1976 Jun IS - 0042-4846 TA - Veterinariia PG - 42-4 CY - USSR IP - 6 JC - XCC EM - 7611 PMID- 948824 CU - 90 TT - Immunobiologicheskaia reaktivnost' u svinei, infitsirovannykh leptospirami, mechennymi radioaktivnym fosforom SO - Veterinariia 1976 Jun;(6):42-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 76240835 AU - Reasoner DJ TI - Microbiology--detection of bacterial pathogens and their occurrence. LA - Eng MH - Amphibia MH - Animal MH - Bacterial Infections/*microbiology MH - Birds MH - Disease Reservoirs MH - Dogs MH - Drug Resistance, Microbial MH - Enterobacteriaceae MH - Human MH - Insects MH - Klebsiella MH - Leptospira MH - Leptospirosis/microbiology MH - Mice MH - Pseudomonas aeruginosa MH - Rats MH - Reptiles MH - Salmonella MH - Vibrio MH - *Water Microbiology PT - JOURNAL ARTICLE PT - REVIEW DA - 761002 DP - 1976 Jun IS - 0043-1303 TA - J Water Pollut Control Fed PG - 1397-410 CY - UNITED STATES IP - 6 VI - 48 JC - KDZ EM - 7611 RF - 127 PMID- 820880 CU - 91 SO - J Water Pollut Control Fed 1976 Jun;48(6):1397-410 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76240834 AU - Craun GF TI - Microbiology--waterborne outbreaks. LA - Eng MH - Amoeba MH - Cholera/microbiology MH - *Disease Outbreaks MH - Dracunculiasis/microbiology MH - Dysentery, Bacillary/microbiology MH - Escherichia coli Infections/microbiology MH - Gastroenteritis/microbiology MH - Giardiasis/microbiology MH - Hepatitis/microbiology MH - Human MH - Leptospirosis/microbiology MH - Meningoencephalitis/microbiology MH - Salmonella Infections/microbiology MH - Schistosomiasis/microbiology MH - Typhoid/microbiology MH - Vibrio Infections/microbiology MH - *Water Microbiology PT - JOURNAL ARTICLE PT - REVIEW DA - 761002 DP - 1976 Jun IS - 0043-1303 TA - J Water Pollut Control Fed PG - 1378-97 CY - UNITED STATES IP - 6 VI - 48 JC - KDZ EM - 7611 RF - 120 PMID- 133251 CU - 92 SO - J Water Pollut Control Fed 1976 Jun;48(6):1378-97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 76237816 AU - Myers DM TI - Serological studies and isolations of serotype hardjo and Leptospira biflexa strains from horses of Argentina. LA - Eng MH - Abattoirs MH - Animal MH - Antibodies, Bacterial/analysis MH - Argentina MH - Blood/microbiology MH - Cross Reactions MH - Epitopes MH - Horse Diseases/immunology/*microbiology MH - Horses/*microbiology MH - Kidney/microbiology MH - Leptospira/*classification/immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - Serotyping PT - JOURNAL ARTICLE DA - 761002 DP - 1976 Jun TA - J Clin Microbiol PG - 548-55 SB - M CY - UNITED STATES IP - 6 VI - 3 JC - HSH AA - Author EM - 7611 AB - Three pathogenic leptosipras and 12 saprophytic Leptospira biflexa strains were isolated from 72 apparently normal horse kidneys collected at an abattoir in Argentina. Cross-agglutination reaction patterns of the pathogens showed that they were antigenically homologous with members of the Hebdomadis group. When one of the strains was compared to Hebdomadis serotypes in reciprocal agglutination-absorption tests, it was found to be serologically homologous to serotype hardjo. This is the first known report of an isolation of this serotype from horses. Serological tests were also carried out on randomly collected abattoir sera from 245 horses to determine the prevalence of equine leptospirosis. Significant antibody titers (1:100 or greater) were found in 74.6% of the sera. Predominant reactions occurred with the antigens pomona, hebdomadis group, pyrogenes, tarassovi, and canicola. Agglutination tests performed with antigen prepared with one of the saprophytic biflexa isolates showed seropositive reactions in 99.1% of the equine sera, with agglutination titers ranging from 1:100 to 1:3,200. Absorption of selected horse sera with the saprophytic strain removed the agglutinins to Leptospira interrogans serotypes. This suggests the possibility that L. biflexa strains may act as an antigenic stimulus and account for some of the persistent multiple cross-reaction patterns of equine sera with pathogenic serotypes. PMID- 59735 CU - 95 SO - J Clin Microbiol 1976 Jun;3(6):548-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76213849 AU - Hanson LE TI - Bovine leptospirosis. LA - Eng MH - Agglutinins MH - Anemia/etiology MH - Animal MH - Cattle MH - *Cattle Diseases/complications/therapy MH - Dihydrostreptomycin Sulfate/therapeutic use MH - Eye Diseases/etiology MH - Female MH - Human MH - Lactation Disorders/etiology MH - Leptospira MH - Leptospirosis/complications/therapy/*veterinary MH - Nephritis/etiology MH - Pregnancy MH - Pregnancy Complications/veterinary MH - Serotyping MH - Species Specificity MH - Vaccination PT - JOURNAL ARTICLE PT - REVIEW DA - 760901 DP - 1976 Jun IS - 0022-0302 TA - J Dairy Sci PG - 1166-70 SB - M CY - UNITED STATES IP - 6 VI - 59 JC - HWV EM - 7610 RF - 51 PMID- 58876 CU - 95 SO - J Dairy Sci 1976 Jun;59(6):1166-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 76268262 AU - Avery TL TI - Letter: Leptospirosis hardjo. LA - Eng MH - Case Report MH - Human MH - Leptospirosis/*complications MH - Male MH - Schizophrenia/*etiology PT - JOURNAL ARTICLE DA - 761020 DP - 1976 May 12 IS - 0028-8446 TA - N Z Med J PG - 336 SB - M CY - NEW ZEALAND IP - 563 VI - 83 JC - OBQ EM - 7612 PMID- 1066560 CU - 88 SO - N Z Med J 1976 May 12;83(563):336 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76217537 AU - Marshall RB TI - The route of entry of leptospires into the kidney tubule. LA - Eng MH - Animal MH - Disease Models, Animal MH - Kidney Tubules, Proximal/*microbiology/pathology MH - Leptospira interrogans/*growth & development MH - Mice MH - Weil's Disease/microbiology/pathology/*transmission PT - JOURNAL ARTICLE DA - 760901 DP - 1976 May IS - 0022-2615 TA - J Med Microbiol PG - 149-52 SB - M CY - ENGLAND IP - 2 VI - 9 JC - J2N AA - Author EM - 7610 AB - To study the migration of Leptospira interrogans serotype pomona through the kidney, conventionally-reared mice aged 2 or 3 weeks were infected intraperitoneally with this organism. Within the first 4 days, the organisms migrated from the capillary lumina to the interstitial tissue and provoked an interstitial oedema. By the 10th day they were seen between the epithelial cells of the proximal convoluted tubules and by the 14th day many were located within tubular lumina. There was no evidence of viable leptospires within the cells of the proximal tubules, though occasionally structures resembling leptospiral fragments inside lysosomes were observed. At no stage during the study were glomerular lesions seen. PMID- 933147 SO - J Med Microbiol 1976 May;9(2):149-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 76173939 AU - Meuter KP AU - Weihrauch TR AU - Kohler H AU - Gnandiger HP TI - [Severe course of an infection with Leptospira grippotyphosa (author's transl)] LA - Ger MH - Adult MH - Case Report MH - Diagnosis, Differential MH - English Abstract MH - Female MH - Fever of Unknown Origin/diagnosis MH - Human MH - Jaundice/diagnosis/*etiology MH - Kidney Failure, Acute/etiology MH - Leptospirosis/complications/*diagnosis/drug therapy MH - Myocarditis/etiology MH - Penicillin G/therapeutic use MH - Prognosis MH - Serodiagnosis MH - Serotyping MH - Tetracyclines/therapeutic use MH - Time Factors PT - JOURNAL ARTICLE DA - 760706 DP - 1976 Apr 9 IS - 0025-8458 TA - Med Klin PG - 631-4 SB - M CY - GERMANY, WEST IP - 15 VI - 71 JC - M4E AA - Author EM - 7608 AB - In a 22 years old female patient severe jaundice, renal failure and myocarditis developed 3 days after the onset of fever and other uncharacteristic symptoms. In dark-field microscopy leptospires were found. Inspite of high-dose penicillin therapy exitus letalis occurred in myocardial and circulatory failure, due to a severe interstitial myocarditis. Leptospira grippotyphosa could be proven serologically as the causative bacterium. It is pointed out, that leptospirosis inspite of their rare occurrence should be included in the differential diagnosis of infections of undetermined origin, especially if jaundice develops. The demonstration of leptospira in blood, cerebro-spinal fluid or urin by means of darkfield microscopy may quickly support the diagnosis. Since the course of severe leptospirosis can be influenced significantly only up to the 4th day after the onset, high-dose penicillin G or tetracycline therapy should be initiated already when the clinical suspicion is present. PMID- 1264008 CU - 90 TT - Foudroyanter Verlauf einer Infektion mit Leptospira grippotyphosa EA - A SO - Med Klin 1976 Apr 9;71(15):631-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 76184284 AU - Hiatt RA AU - Sulzer CR TI - Leptospirosis in a rural barrio of Guaynabo, Puerto Rico. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Puerto Rico MH - Rural Population PT - JOURNAL ARTICLE DA - 760802 DP - 1976 Apr IS - 0004-4849 TA - Bol Asoc Med P R PG - 69-75 CY - PUERTO RICO IP - 4 VI - 68 JC - AB4 EM - 7609 PMID- 1063572 CU - 88 SO - Bol Asoc Med P R 1976 Apr;68(4):69-75 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 77126822 AU - Straton C AU - Straton A AU - Teodorovici G AU - Bercovici C AU - Buzdugan I AU - Beldiman N AU - Vasiliu D AU - Vasiliu A AU - Soana G AU - Soana R TI - [Study of a leptospirosis focus with L. grippotyphosa in a Subcarpathian zone. III. Postepizooto-epidemic evolution of the focus] LA - Rum MH - Animal MH - Animals, Domestic MH - Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/*etiology MH - Romania PT - JOURNAL ARTICLE DA - 770430 DP - 1976 Apr-Jun IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 233-6 CY - ROMANIA IP - 2 VI - 80 JC - SHP EM - 7706 PMID- 1019458 CU - 88 TT - Studiul unui focar de leptospiroza cu L. grippotyphosa intr-o zona subcarpatica. Nota III. Evolutia postepizooto-epidemica focarului EA - A SO - Rev Med Chir Soc Med Nat Iasi 1976 Apr-Jun;80(2):233-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 77066602 AU - Andress CE AU - Greenfield J AU - Macdonald K TI - Some leptospira agglutinins detected in domestic animals in British Columbia. LA - Eng MH - Agglutinins/analysis MH - Animal MH - British Columbia MH - Cattle MH - Dogs MH - Horses MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Swine PT - JOURNAL ARTICLE DA - 770224 DP - 1976 Apr IS - 0008-4050 TA - Can J Comp Med PG - 215-7 SB - M CY - CANADA IP - 2 VI - 40 JC - CI0 AA - Author EM - 7704 AB - During a period of six years 7,555 bovine sera, 421 canine sera, 251 porcine sera and 135 equine sera were tested for agglutinins to Leptospira interrogans serotypes canicola, grippotyphosa, hardjo, icterohemorrhagiae, pomona and sejroe. The bovine sera reacted predominantly with hardjo and/or sejroe at a rate of 15% compared to 3.5% with pomona. Breeding or abortion problems were associated with pomona but not with sejroe/hardjo agglutinins. The canine sera reacted to canicola (9.9%y and icterohemorrhagiae (5.4%), tcted predominantly with canicola (8.9%) and icterohemorrhagiae (8.1%). PMID- 1000389 CU - 88 SO - Can J Comp Med 1976 Apr;40(2):215-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 76272632 AU - Bolotskii IA AU - Kundriukov AI AU - Tereshchenko NI AU - Shiliakin VK TI - [Lysozyme level in swine with leptospirosis] LA - Rus MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Specificity MH - Leptospirosis/immunology/*veterinary MH - Muramidase/*blood MH - Swine MH - Swine Diseases/*immunology MH - Time Factors PT - JOURNAL ARTICLE DA - 761101 DP - 1976 Apr IS - 0042-4846 TA - Veterinariia PG - 55-6 CY - USSR IP - 4 JC - XCC EM - 7612 PMID- 986719 CU - 90 SO - Veterinariia 1976 Apr;(4):55-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76218466 AU - Rigby C TI - Natural infections of guinea-pigs. LA - Eng MH - Animal MH - Bordetella Infections/veterinary MH - Bronchopneumonia/veterinary MH - Coccidiosis/veterinary MH - Cytomegalovirus Infections/veterinary MH - *Guinea Pigs MH - Leptospirosis/veterinary MH - Lymphocytic Choriomeningitis/veterinary MH - Mite Infestations/veterinary MH - Mycoplasma Infections/veterinary MH - Parainfluenza Virus 1, Human MH - Pasteurella Infections/veterinary MH - Pediculosis/veterinary MH - Pneumococcal Infections/veterinary MH - Pneumonia/veterinary MH - Protozoan Infections/veterinary MH - *Rodent Diseases MH - Salmonella Infections, Animal MH - Streptococcal Infections/veterinary MH - Tinea/veterinary PT - JOURNAL ARTICLE DA - 760823 DP - 1976 Apr IS - 0023-6772 TA - Lab Anim PG - 119-42 SB - M CY - ENGLAND IP - 2 VI - 10 JC - KYQ EM - 7610 PMID- 180326 CU - 96 SO - Lab Anim 1976 Apr;10(2):119-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 76221081 AU - Avery TL TI - Letter: Leptospirosis hardjo. LA - Eng MH - Case Report MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Schizophrenia, Disorganized/*etiology PT - JOURNAL ARTICLE DA - 760823 DP - 1976 Mar 24 IS - 0028-8446 TA - N Z Med J PG - 208 SB - M CY - NEW ZEALAND IP - 560 VI - 83 JC - OBQ EM - 7610 PMID- 1064805 CU - 88 SO - N Z Med J 1976 Mar 24;83(560):208 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 76179425 AU - Ellis WA AU - Bryson DG AU - McFerran JB TI - Abortion associated with mixed Leptospira/equid herpesvirus 1 infection. LA - Eng MH - Abortion, Veterinary/*etiology/pathology MH - Animal MH - Female MH - *Herpesviridae MH - Herpesviridae Infections/complications/pathology MH - *Herpesvirus 1, Equid MH - Horse Diseases/*etiology/pathology MH - Horses MH - Leptospirosis/complications/pathology/*veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 760706 DP - 1976 Mar 13 IS - 0042-4900 TA - Vet Rec PG - 218-9 SB - M CY - ENGLAND IP - 11 VI - 98 JC - XBS EM - 7608 PMID- 178087 CU - 93 SO - Vet Rec 1976 Mar 13;98(11):218-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 76190480 AU - Bragger JM AU - Adler B TI - A card test for the serodiagnosis of human leptospirosis. LA - Eng MH - *Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Human MH - Leptospira interrogans/*immunology MH - Leptospirosis/*diagnosis MH - Rabbits PT - JOURNAL ARTICLE DA - 760802 DP - 1976 Mar IS - 0021-9746 TA - J Clin Pathol PG - 198-202 SB - A SB - M CY - ENGLAND IP - 3 VI - 29 JC - HT3 AA - Author EM - 7609 AB - A macroscopic agglutination test for detecting leptospiral antibodies in human sera is described. The test utilizes a stained preparation of non-pathogenic leptospires and is performed on the Brewer diagnostic cards used for bovine brucellosis screening. The agglutination of the stained antigen is more easily observed than the current macroscopic slide test using unstained leptospiral antigens. The non-pathogenic serotype patoc is agglutinated by sera from humans infected with serotypes pomona, hardjo, ballum, and copenhageni with a sensitivity of 94% in comparison with the microscopic agglutination test. PMID- 1270601 SO - J Clin Pathol 1976 Mar;29(3):198-202 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 76196689 AU - Hodges RT AU - Stocker RP AU - Buddle JR TI - Leptospira interrogans serotype pomona infection and leptospiruria in vaccinated pigs. LA - Eng MH - Animal MH - Bacteriuria/prevention & control/*veterinary MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/*veterinary MH - Weil's Disease/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 760802 DP - 1976 Mar IS - 0048-0169 TA - N Z Vet J PG - 37-9 CY - NEW ZEALAND IP - 3 VI - 24 JC - OBZ EM - 7609 PMID- 1063950 CU - 88 SO - N Z Vet J 1976 Mar;24(3):37-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 77114378 AU - Mailloux M AU - Schneider R AU - Gervaise G TI - [Human leptospirosis in Martinique] LA - Fre MH - Adolescence MH - Adult MH - Antibodies, Bacterial/analysis MH - Child MH - Climate MH - Disease Reservoirs MH - English Abstract MH - Environment MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology/immunology/microbiology MH - Male MH - Martinique MH - Seasons MH - Species Specificity PT - JOURNAL ARTICLE DA - 770415 DP - 1976 Mar-Apr IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 144-51 SB - M CY - FRANCE IP - 2 VI - 69 JC - C4G AA - Author EM - 7706 AB - Eco-geographic conditions are good for spread of Leptospiroses in Martinique. Leptospiroses are widespread in all parts of the Island. Many people have animals in inhabitation area. When they are sought, Leptospiroses can be diagnosed. During 3 years, we found many cases confirmed by biological diagnosis (immunological research of antibodies). Icterohaemorrhagiae is the first serogroup encountered and the most frequent. After follow Canicola, Ballum, Cynopteri and Javanica. Actually, Leptospiroses are a disease more frequent than is generally thought in Martinique. But only the severe cases are hospitalized, so diagnosed. Many cases of fever of unknown origin can be Leptospiroses. PMID- 1037091 CU - 88 TT - Leptospiroses humaines en Martinique EA - A SO - Bull Soc Pathol Exot Filiales 1976 Mar-Apr;69(2):144-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76202138 AU - Sixl W AU - Stunzner D AU - Withalm H TI - [Tests for anthropozoonoses in sera of farmers in eastern-Austria. I. Communication (author's transl)] LA - Ger MH - Agricultural Workers' Diseases/*epidemiology/transmission MH - Animal MH - Arbovirus Infections/epidemiology MH - Austria MH - English Abstract MH - Human MH - Leptospirosis/epidemiology MH - Listeria Infections/epidemiology MH - Lymphocytic Choriomeningitis/epidemiology MH - Mycoplasma Infections/epidemiology MH - Rickettsia Infections/epidemiology MH - Tularemia/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 760802 DP - 1976 Mar IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 265-70 SB - M CY - GERMANY, WEST IP - 2 VI - 234 JC - Y52 AA - Author EM - 7609 AB - Because of human disease and the evidence of antibodies in domestic- and wild animal-sera, human sera were tested for various anthropozoonoses in three districts of the so called "Seewinkel" (Eastern-Austria). Positive reactions were found for listeriosis, tularemia, leptospirosis, ornithosis, Q-fever, rickettsiae of the RMSF- group "Stamm B", mycoplasmosis, TBE-(FSME-), Sindbis-, West Nil-VIRUS. These results are indicators for the occurrence of the pathogens and are supported by the positive results already found at serological tests of domestic and wild animals. PMID- 946920 CU - 88 TT - Untersuchungen auf Anthropozoonosen bei Landarbeitern in Ostosterreich. I. Mitteilung EA - A SO - Zentralbl Bakteriol [Orig A] 1976 Mar;234(2):265-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76172563 AU - Ohr C AU - Schmidt M AU - Engelhardt K AU - Straub E TI - [Leptospirosis epidemic (L. grippothyphosa) in the Mainz area, concerning the pediatric age group (author's transl)] LA - Ger MH - Ampicillin/therapeutic use MH - Cephalosporins/therapeutic use MH - Child MH - Child, Preschool MH - Diagnosis, Differential MH - Disease Outbreaks MH - English Abstract MH - Germany, West MH - Human MH - Infant MH - Leptospirosis/*diagnosis/drug therapy/epidemiology MH - Lymphadenitis/diagnosis MH - Meningitis/diagnosis PT - JOURNAL ARTICLE DA - 760706 DP - 1976 Mar IS - 0300-8630 TA - Klin Padiatr PG - 156-60 SB - M CY - GERMANY, WEST IP - 2 VI - 188 JC - KWE AA - Author EM - 7608 AB - 31 children, presenting with rather uncharacteristic symptoms of an infectious disease and being referred to this clinic mostly because of lymphadenitis of the neck (81%) and/or signs of meningitis (45%), were seen within a period of only eight weeks and proved to suffer from Leptospirosis (L. grippotyphosa). The majority of the patients belonged to the age group of one to six years and lived in rural environs. Our observation is considered to relate to a Leptospirosis epidemic and suggests, as opposed to the general acceptance, a much higher incidence of Leptospirosis in this country and, moreover, in children. PMID- 944352 CU - 88 TT - Leptospirose-Epidemie (L. grippotyphosa) bei Kindern im Einzugsgebiet der Universitats-Kinderklinik Mainz EA - A SO - Klin Padiatr 1976 Mar;188(2):156-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 76270172 AU - Higa HH AU - Fujinaka IT TI - Prevalence of rodent and mongoose leptospirosis on the Island of Oahu. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - *Carnivora MH - Hawaii MH - Kidney/microbiology MH - Leptospira/classification/immunology/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Mice MH - *Mongoose MH - Rats MH - Rodent Diseases/*epidemiology MH - Serotyping PT - JOURNAL ARTICLE DA - 761029 DP - 1976 Mar-Apr IS - 0033-3549 TA - Public Health Rep PG - 171-7 SB - A SB - M CY - UNITED STATES IP - 2 VI - 91 JC - QJA AA - Author EM - 7612 AB - Sporadic occurrences of human leptospirosis in recent years throughout the State of Hawaii have resulted in at least one death. Because of the apparent association of rodents and possibly mongooses with human leptospiral infections, a survey for leptospirosis was conducted among rodents as well as mongooses on Oahu. No such work had been recorded since a survey of rodents and mongooses for leptospirosis 31 years ago. In the current work, the prevalence of rodent and mongoose leptospirosis in the districts of Oahu was determined by the kidney- culture method. A serologic study of the rodents and mongooses subjected to kidney culturing was also conducted by use of the microscopic slide agglutination test. There were 1.2 times as many kidney culture results that were positive as serologic results. High prevalence of rodent leptospirosis were found where there was considerable rainfall or fresh surface water such as from streams. The overall leptospirosis prevalence for rodents was 23.4 percent, and for mongooses it was 23.0 percent. The Norway rat (Rattus norvegicus) had the highest infection rate, 33.3 percent, and the predominant (72.2 percent) organism in these infections was Leptospira icterohaemorrhagiae, which causes Weil's disease in man. Observations of rodent leptospirosis recorded 31 years ago were compared with results of the current study. The mongoose (Herpestes auropunctatus) is the preeminent carrier of Leptospira sejroe, a serotype that generally causes a mild form of leptospirosis in man. PMID- 822470 CU - 91 SO - Public Health Rep 1976 Mar-Apr;91(2):171-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 76177491 AU - Hussaini SN AU - Ruby KR TI - Comparative studies on the use of 5-fluorouracil in two different media as a selective agent for isolation of Leptospira. LA - Eng MH - Comparative Study MH - Culture Media MH - Escherichia coli/drug effects/growth & development MH - Fluorouracil/*pharmacology MH - Leptospira/growth & development/*isolation & purification MH - Staphylococcus aureus/drug effects/growth & development PT - JOURNAL ARTICLE DA - 760706 DP - 1976 Mar IS - 0034-5288 TA - Res Vet Sci PG - 148-50 SB - M CY - ENGLAND IP - 2 VI - 20 JC - R7D AA - Author EM - 7608 AB - Incorporation of 5-fluorouracil at concentrations of 100-150 mug/ml in Korthof's medium was found to be effective in inhibiting staphylococci and Escherichia coli without adversely affecting leptospiral growth when cultures were incubated at 30 degrees C or at room temperature (15- 22 degrees C). No growth was detected in cultures incubated at 37 degrees C. it was concluded that Korthof's medium containing 5- fluorouracil at these concentrations forms a useful selective medium for the isolation of leptospires when incubated at appropriate temperatures. PMID- 772772 CU - 90 SO - Res Vet Sci 1976 Mar;20(2):148-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 77164674 AU - McKiernan J AU - O'Brien DJ AU - Dundon S TI - Leptospirosis and acalculous cholecystitis. LA - Eng MH - Case Report MH - Cholecystitis/*complications MH - Human MH - Infant MH - Ireland MH - Leptospira/isolation & purification MH - Leptospirosis/*complications MH - Male PT - JOURNAL ARTICLE DA - 770622 DP - 1976 Feb 14 IS - 0021-129X TA - Ir Med J PG - 71-2 CY - IRELAND IP - 3 VI - 69 JC - GXD EM - 7708 PMID- 1025049 SO - Ir Med J 1976 Feb 14;69(3):71-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 76194509 AU - Vladyka AS AU - Dotsenko AV AU - Mikhalevskaia LA TI - [Treatment with hemodialysis of acute renal insufficiency in leptospirosis] LA - Rus MH - Adult MH - Case Report MH - *Hemodialysis MH - Human MH - Kidney Failure, Acute/etiology/*therapy MH - Leptospirosis/*complications MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 760803 DP - 1976 Feb IS - 0023-2149 TA - Klin Med (Mosk) PG - 131-4 CY - USSR IP - 2 VI - 54 JC - KW2 EM - 7609 PMID- 1271706 TT - Lechenie gemodializom ostroi pochechnoi nedostatochnosti pri leptospiroze SO - Klin Med (Mosk) 1976 Feb;54(2):131-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 76171729 AU - Ellinghausen HC AU - Painter GM TI - Growth, survival, antigenic stability, and virulence of Leptospira interrogans serotype canicola. LA - Eng MH - Animal MH - Antigens, Bacterial/analysis MH - Bacterial Vaccines MH - Culture Media MH - Hamsters MH - *Leptospira interrogans/growth & development/immunology/pathogenicity MH - Virulence PT - JOURNAL ARTICLE DA - 760706 DP - 1976 Feb IS - 0022-2615 TA - J Med Microbiol PG - 29-37 SB - M CY - ENGLAND IP - 1 VI - 9 JC - J2N AA - Author EM - 7608 AB - Leptospira interrogans serotype canicola (strain NADL A-13) grew from inocula as small as two cells in liquid polysorbate 80 medium (P-80 medium, in P-60, P-40 and P-20 media, and in P-80 medium from which polysorbate, NH4C1 or thiamine had been omitted. It grew well initially in vitamin B12-deleted P-80 medium, but only with inocula as large as 26 x 10(4) cells per ml. P-80 medium lacking both polysorbate and NH4Cl supported light growth from small inocula, but the omission of thiamine and vitamin B12 in addition seriously affected the properties of the medium. Where readily detectable growth did not develop in liquid nutrient-deleted medium, viable ortanisms could often be demonstrated indirectly by subculture to semisolid medium, and their occurrence was influenced by the presence of albumin, thiamine, and vitamin B12. Growth on semisolid media was comparable with that in liquid media of similar composition. The absence of polysorbate 80, thiamine, or vitamin B12 prevented the appearance of Dinger's zones of growth from small inocula. Antigenic composition as measured by microscopic agglutination tests with homologous and heterologous antisera was not appreciably affected by repeated subculturing in various complete and incomplete media. Homogenates of infected-hamster-kidney tissue in bovine serum-albumin diluent still contained viable organisms after 60 days' storage at 23-25 degrees C. Organisms derived from this material after 3 and 16 days' storage showed no loss of virulence. Organisms grown in artificial culture showed no loss of virulence after storage in bovine albumin diluent or phosphate buffer for 7 days at 23-25 degrees C. Cultures of the organism survived without loss of virulence for 15 months in 13 semisolid media of differing complexity. Single colonies derived from five different solid media were grown in semisolid forms of the parent media and stored at 23-25 degrees C for 10 months without loss of virulence. PMID- 1263246 SO - J Med Microbiol 1976 Feb;9(1):29-37 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76265511 AU - Kitaoka M AU - Mori M AU - Armitsu Y TI - Identification of Leptospira pyrogenes isolated from a swine in the Philippines in 1967. LA - Eng MH - Animal MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification MH - Serotyping MH - Swine/*microbiology PT - JOURNAL ARTICLE DA - 761020 DP - 1976 Feb IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 49-51 SB - M CY - JAPAN IP - 1 VI - 29 JC - KLZ EM - 7612 PMID- 957527 SO - Jpn J Med Sci Biol 1976 Feb;29(1):49-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 76265510 AU - Kitaoka M AU - Otsuka S TI - Leptospira canicola isolated from Apodemus speciosus speciosus in Kyushu. LA - Eng MH - Animal MH - Leptospira canicola/immunology/*isolation & purification MH - Rodentia/*microbiology MH - Serotyping PT - JOURNAL ARTICLE DA - 761020 DP - 1976 Feb IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 45-7 SB - M CY - JAPAN IP - 1 VI - 29 JC - KLZ EM - 7612 PMID- 957526 SO - Jpn J Med Sci Biol 1976 Feb;29(1):45-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 76130111 AU - Naidoo PM TI - Acute renal failure. Experience with 52 patients treated at Livingstone Hospital. LA - Eng MH - Acute Disease MH - Adult MH - Blood Coagulation Disorders/complications MH - Case Report MH - Female MH - Furosemide/therapeutic use MH - Human MH - Hypotension/complications MH - Infection/complications MH - Jaundice/complications MH - Kidney Failure, Acute/drug therapy/*etiology MH - Leptospirosis/complications MH - Male MH - Pancreatitis/complications MH - Pregnancy MH - Pregnancy Complications MH - Respiratory Insufficiency/complications MH - Typhoid/complications PT - JOURNAL ARTICLE DA - 760419 DP - 1976 Jan 17 IS - 0038-2469 TA - S Afr Med J PG - 78-80 SB - M CY - SOUTH AFRICA IP - 3 VI - 50 JC - U4R AA - Author EM - 7606 AB - Fifty-two cases of acute renal failure at Livingstone Hospital were studied. Twenty-two cases were obstetric, 10 surgical and 20 medical. The aetiological factors are tabulated and the pathophysiology is reported. Clinical features and biochemical abnormalities are presented. Infection was the commonest associated factor, followed by hypotension and volume problems, coagulation disorders, jaundice and hepatic failure, respiratory failure, pancreatitis and typhoid fever. In 7 of the medical cases the aetiology was unknown and was assumed to be toxic. A case history of a patient with leptospirosis, acute renal failure, liver failure and pancreatitis is presented. The mortality in this series was 32%. PMID- 1251280 SO - S Afr Med J 1976 Jan 17;50(3):78-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 76111804 AU - Muller-Peddinghaus R AU - Schaefer B AU - Greiffenhagen U AU - Wirth W AU - Trautwein G TI - [Pathology, clinical aspects and etiology of glomerulonephritis and interstitial nephritis in dogs] LA - Ger MH - Animal MH - Blood Proteins/analysis MH - Complement 3/analysis MH - Creatine/blood MH - *Dog Diseases/complications/etiology/metabolism MH - Dogs MH - English Abstract MH - Glomerulonephritis/immunology/veterinary MH - Hematuria MH - IgG/analysis MH - Immune Complex Diseases MH - Kidney/pathology MH - Leptospirosis/veterinary MH - Nephritis/*veterinary MH - Nephritis, Interstitial/blood/microbiology/veterinary MH - Nephrotic Syndrome/veterinary MH - Proteinuria MH - Pyelonephritis MH - Uremia MH - Vesico-Ureteral Reflux/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 760320 DP - 1976 Jan 15 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 21-4 concl CY - GERMANY, WEST IP - 2 VI - 89 JC - 9Q8 EM - 7605 RF - 61 PMID- 129057 CU - 92 TT - Beitrag zur Pathologie, Klinik und Atiologie der Glomerulonephritis und interstitiellen Nephritis des Hundes EA - A SO - Berl Munch Tierarztl Wochenschr 1976 Jan 15;89(2):21-4 concl ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 76196840 AU - Gyorgy B TI - [Clinical observations on patients with leptospirosis] LA - Hun MH - Human MH - Leptospirosis/*physiopathology PT - JOURNAL ARTICLE DA - 760802 DP - 1976 IS - 0030-6002 TA - Orv Hetil PG - 1089-91 CY - HUNGARY IP - 18 VI - 117 JC - OL8 EM - 7609 PMID- 1272564 TT - Klinikai megfigyelesek leptospirosisban szenvedo betegeken SO - Orv Hetil 1976;117(18):1089-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76178960 AU - Everard CO AU - Green AE AU - Glosser JW TI - Leptospirosis in Trinidad and Grenada, with special reference to the mongoose. LA - Eng MH - Animal MH - Carnivora/*parasitology MH - Complement Fixation Tests MH - *Disease Reservoirs MH - Epidemiologic Methods MH - Human MH - Leptospira/isolation & purification MH - Leptospira canicola/*isolation & purification MH - Leptospirosis/*diagnosis/epidemiology MH - Mongoose/*parasitology MH - Support, U.S. Gov't, P.H.S. MH - Trinidad and Tobago MH - West Indies PT - JOURNAL ARTICLE DA - 760706 DP - 1976 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 57-61 SB - M CY - ENGLAND IP - 1 VI - 70 JC - WBU AA - Author EM - 7608 AB - In Trinidad, six Leptospira isolates were made from 957 febrile patients between 1968 amd 1972. In addition, CF antibodies were detected in 6-6% of febrile patients and human survey sera collected during this period. In 1972 alone, 10-4% (38/363) of sera examined had CF titres consistent with positive exposure to the disease. Grenada does not report leptospirosis, but the disease is common in mongooses in both Trinidad and Grenada. Serogroups Icterohaemorrhagiae, Pomona and Canicola are present in Grenada with 35-2% of mongooses examined being seropositive. Five Canicola strains of Leptospira were isolated from mongooses in Trinidad and serological studies showed that this was the most common serogroup from mongooses on the island. A total of 31 strains recorded from at least seven different serogroups and eight named serotypes have been isolated from humans, rats and mongooses in Trinidad. Human leptospirosis is probably more common in the Caribbean than the medical records indicate. PMID- 1265819 CU - 90 SO - Trans R Soc Trop Med Hyg 1976;70(1):57-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 76147047 AU - Tripathy DN AU - Hanson LE TI - Some observations on chronic leptospiral carrier state in gerbils experimentally infected with Leptospira grippotyphosa. LA - Eng MH - Animal MH - Bacteriuria/veterinary MH - Carrier State/immunology/microbiology/*veterinary MH - *Gerbillinae MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - *Rodent Diseases/immunology/microbiology PT - JOURNAL ARTICLE DA - 760602 DP - 1976 Jan IS - 0090-3558 TA - J Wildl Dis PG - 55-8 SB - M CY - UNITED STATES IP - 1 VI - 12 JC - KEM AA - Author EM - 7607 AB - Leptospiruria with persistent microscopic agglutinating antibody titers were maintained in gerbils that became carriers following experimental infection with Leptospira grippotyphosa, strain F 4397. Leptospires were isolated from kidneys of a gerbil which died 28 months after experimental inoculation. PMID- 1255914 SO - J Wildl Dis 1976 Jan;12(1):55-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 76139068 AU - Smith RE AU - Williams IA AU - Kingsbury ET TI - Serologic evidence of equine leptospirosis in the northeast United States. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Horse Diseases/immunology MH - Horses/*immunology MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/veterinary MH - United States PT - JOURNAL ARTICLE DA - 760602 DP - 1976 Jan IS - 0010-8901 TA - Cornell Vet PG - 105-9 SB - M CY - UNITED STATES IP - 1 VI - 66 JC - DRI AA - Author EM - 7607 AB - Serologic testing for leptospiral antibody was conducted with the macroscopic agglutination test on 1,346 equine serum samples. These were collected from clinically normal horses in 123 purebred herds in the Northeast. Sixty-eight samples (5%) from the population tested reacted at significant levels (1:40 or higher) to one or more of the 5 serotype antigens used. These reactors were from 38 (31%) of the herds tested. Reactions to serotype pomona predominated in 25 (72%) of these 38 herds. Smaller numbers of herds had reactors to canicola, icterohemorrhagiae and grippotyphosa. No significant reactions to serotype hardjo were detected. PMID- 1253604 SO - Cornell Vet 1976 Jan;66(1):105-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 76110033 AU - Killinger AH AU - Taylor PL AU - Huhn RG AU - Hanson LE AU - Mansfield ME TI - Immunity to leptospirosis: renal changes in vaccinated cattle given challenge inoculum. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*immunology/pathology MH - Kidney/*pathology MH - Kidney Diseases/immunology/pathology/*veterinary MH - Leptospirosis/immunology/pathology/*veterinary MH - Support, U.S. Gov't, Non-P.H.S. MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 760311 DP - 1976 Jan IS - 0002-9645 TA - Am J Vet Res PG - 93-4 SB - M CY - UNITED STATES IP - 1 VI - 37 JC - 40C AA - Author EM - 7605 AB - Resistance to renal leptospirosis was demonstrated in cattle vaccinated with Leptospira interrogans serotype pomona bacterin. Fewer vaccinated cattle given challenge inoculum of virulent serotype pomona leptospires 12 months after vaccination had kidneys with gross focal lesions in the cortex than did nonvaccinated controls. Histopathologic changes characteristically associated with renal leptospirosis occurred less frequently and renal tissue damage was less severe in vaccinated cattle than in nonvaccinated controls. The isolation of serotype pomona from only 1 of 29 vaccinated cattle, compared to 7 isolations from 11 nonvaccinated cattle, at 26 days after challenge inoculum was given, indicated that mild renal infection occurred only infrequently in vaccinated cattle. It appeared that challenge inoculation of vaccinated cattle with virulent serotype pomona leptospires stimulated an accelerated secondary immune response in which immunity limited the multiplication of leptospires in the kidney. PMID- 1247204 SO - Am J Vet Res 1976 Jan;37(1):93-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 76110023 AU - Tripathy DN AU - Hanson LE AU - Mansfield ME TI - Evaluation of the immune response of cattle to leptospiral bacterins. LA - Eng MH - Animal MH - *Antibody Formation MH - *Bacterial Vaccines MH - Cattle/*immunology MH - Cattle Diseases/pathology MH - Cell Wall/immunology MH - Female MH - Hamsters MH - Leptospira/*immunology MH - Leptospirosis/pathology/veterinary MH - Nephritis, Interstitial/pathology/veterinary PT - JOURNAL ARTICLE DA - 760311 DP - 1976 Jan IS - 0002-9645 TA - Am J Vet Res PG - 51-5 SB - M CY - UNITED STATES IP - 1 VI - 37 JC - 40C AA - Author EM - 7605 AB - Cattle were vaccinated against leptospirosis with 3 bacterin preparations: (a) trivalent (serotypes grippotyphosa, pomona, and hardjo) whole cell bacterin; (b) bivalent pomona and hardjo whole cell bacterin; and (c) pentavalent (canicola, grippotyphosa, icterohaemorrhagiae, pomona, and hardjo) cell wall bacterin. Microscopic agglutinating antibody responses in cattle given the last- named bacterin were higher than those in cattle vaccinated with the 2 whole cell bacterins (trivalent and bivalent). However, microscopic agglutinating antibody responses occurred in all vaccinated cattle after they were given a challenge inoculation of serotype hardjo. Leptospires were isolated from 2 of 4 challenge controls (i.e., not given any bacterin), but none of the 15 vaccinated cattle given any one of the bacterins and then challenge inoculated with hardjo became culturally positive. It was concluded that the 3 multivalent bacterins were protective against experimental challenge inoculation of hardjo. PMID- 1247197 SO - Am J Vet Res 1976 Jan;37(1):51-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 76106747 AU - Gazhiev VV AU - Bondarev LS TI - [Leptospiral jaundice in miners] LA - Rus MH - Acute Disease MH - Adult MH - Animal MH - Case Report MH - *Coal Mining MH - Disease Vectors MH - Human MH - Jaundice/*physiopathology MH - Leptospirosis/*physiopathology MH - Male MH - Occupational Diseases/*physiopathology MH - Rats MH - Ukraine PT - JOURNAL ARTICLE DA - 760324 DP - 1976 Jan IS - 0049-6804 TA - Vrach Delo PG - 137-9 CY - USSR IP - 1 JC - XLS EM - 7605 PMID- 1246845 TT - Zheltushnyi leptospiroz u shakhterov SO - Vrach Delo 1976 Jan;(1):137-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 79180290 AU - Tripathy DN AU - Hanson LE AU - Nervig RM AU - Cardella MA AU - Mansfield ME TI - Evaluation of the immune response of cattle to single and multiple vaccination with a polyvalent leptospiral bacterin. LA - Eng MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Bacterial Vaccines/administration & dosage/*immunology MH - Cattle MH - Cattle Diseases/*prevention & control MH - Leptospira/*immunology MH - Leptospirosis/prevention & control/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 790716 DP - 1976 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 173-81 CY - UNITED STATES IP - 80 JC - PY5 EM - 7909 PMID- 1078073 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1976;(80):173-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 76196685 AU - Philip NA TI - Leptospirosis: New Zealand's no. 1 dairy occupational disease. LA - Eng MH - Agricultural Workers' Diseases/*microbiology MH - *Dairying MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*microbiology MH - New Zealand PT - JOURNAL ARTICLE DA - 760802 DP - 1976 Jan-Feb IS - 0048-0169 TA - N Z Vet J PG - 6-8 CY - NEW ZEALAND IP - 1-2 VI - 24 JC - OBZ EM - 7609 PMID- 1063946 CU - 88 SO - N Z Vet J 1976 Jan-Feb;24(1-2):6-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 78253831 AU - Kemenes F AU - Suveges T TI - Leptospira-induced repeated abortion in sows. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Female MH - Leptospirosis/complications/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*complications PT - JOURNAL ARTICLE DA - 781018 DP - 1976 IS - 0001-7205 TA - Acta Vet Acad Sci Hung PG - 395-403 CY - HUNGARY IP - 4 VI - 26 JC - 27P EM - 7812 PMID- 1052655 SO - Acta Vet Acad Sci Hung 1976;26(4):395-403 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 77166465 AU - Kitaoka M AU - Hyakutare S AU - Mori M TI - Identification of Leptospira andamana isolated from the spinal fluid of a fatal case of leptospirosis in Sao Paulo, 1963. LA - Eng MH - Adult MH - Agglutination Tests MH - Brazil MH - Case Report MH - Cerebrospinal Fluid/microbiology MH - Human MH - Leptospira/*classification/isolation & purification MH - Leptospira interrogans/classification MH - Leptospirosis/*microbiology/mortality MH - Male PT - JOURNAL ARTICLE DA - 770611 DP - 1976 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 437-42 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 20 JC - IEV AA - Author EM - 7708 AB - The IAL-S. P. strain was isolated from the spinal fluid of a patient male, aged 35, black, a sewer worker with fever, myalgia, jaundice, vomiting and meningitis symptoms with a 5-day incubation period after the lower half of the body had been submerged for 2 hours in sewers when unblocking a drain. Leptospires were isolated by direct inoculation of the spinal fluid taken on the 9th day of the illness into the Fletcher's media and into guinea pigs by the intraperitoneal route. The patient gave a positive agglutination test for L. andamana with cross-reaction with L. sejroe. The strain was identified as L. andamana by the cross-agglutination-lysis test and the cross-absorption test. The IAL-S. P. strain is undoubtedly not saprophytic but parasitic and pathogenic for man and animals, however its biological properties resist to the oligodynamic action of Cu and Hg and the 8-azoguanine action as in the case of the Patoc 1 strain. I could be recommended to reconsider whether the strain belongs to L. interrogans, L. biflexa or to another group because the grounds for L. andamana being saprophytic were denied by this report. PMID- 1035921 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1976;20(4):437-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77095387 AU - Fuchs GH AU - Burger G TI - Nephelometric density adjustment of leptospiral antigen. LA - Eng MH - Agglutination Tests/instrumentation/*standards MH - Antibodies, Bacterial/*analysis MH - Diagnosis, Differential MH - Human MH - Leptospira interrogans/*immunology MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 770315 DP - 1976 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 377-81 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 21 JC - IEV AA - Author EM - 7705 AB - In testing leptospirosis by microagglutination, reproducibility of the results is affected by population age and germ concentration. These undersirable factors can be avoided if antibody identification is made with cultures incubated for 7 to 21 days and adjusted to 50 X 10(6) leptospires per millilitre. Most suitable for the purpose is an analogue mode based on nephelometry and the probability theory. The obtained statistical data furnish calculated and tabulated apparatus values which are used for standardizing with the aid of a newly developed nepheloflask with compression-spring stirrer. PMID- 1034658 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1976;21(3):377-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77052449 AU - Fuchs GH AU - Burger G TI - Nephelometric density adjustment of leptospiral antigen. LA - Eng MH - *Agglutination Tests MH - Antigens, Bacterial/*analysis MH - Leptospira interrogans/*immunology MH - Spectrophotometry/instrumentation PT - JOURNAL ARTICLE DA - 770128 DP - 1976 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 377-81 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 21 JC - IEV AA - Author EM - 7703 AB - In testing leptospirosis by microagglutination, reproducibility of the results is affected by population age and germ concentration. These undesirable factors can be avoided if antibody identification is made with cultures incubated for 7 to 21 days and adjusted to 50 X 10(6) leptospires per mililitre. Most suitable for the purpose is an analogue mode based on nephelometry and the probability theory. The obtained statistical data furnish calculated and tabulated apparatus values which are used for standardizing with the aid of a newly developed nepheloflask with compression-spring stirrer. PMID- 1033229 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1976;21(3):377-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 77176329 AU - Sherkov Sh AU - Khalacheva M AU - Kararizova L TI - [Epizootiology of leptospirosis on industrial swine-breeding complexes] LA - Bul MH - Animal MH - Bulgaria MH - English Abstract MH - Leptospira/isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Swine MH - Swine Diseases/*epidemiology/microbiology PT - JOURNAL ARTICLE DA - 770630 DP - 1976 IS - 0506-8215 TA - Vet Med Nauki PG - 68-74 SB - M CY - BULGARIA IP - 8 VI - 13 JC - XCE AA - Author EM - 7708 AB - Epizoovotiologic studies were carried out at two industrial pigbreeding complexes for 40,000 and 33,000 animals with a record of leptospirosis. The serologic examination of pigs made use of the microagglutination reaction in the investigation of a total of 3,793 blood samples by groups corresponded to the technology of raising introduced at such complexes--sows, growing animals, replacement animals, and pigs for fattening, along with the study of 20,914 blood samples taken from pigs in various regions of the country. The total number of positively reacting pigs accounted for 12.9 per cent. Highest was the percent of positively reacting sows and growing pigs--19.1 and 12.9, while the replacement animals showed 8.31. No positively reacting animals were found among the pigs for fattening. Highest titers were noted among sows--up to 1:12,800 (infectious), and lowest among growing pigs--up to 1:100 (postnatal). State are the substantial economic losses caused by abortions and stillborn piglets--11 and 23 per cent, resp., for the two complexes. The basic Leptospira type for the two complexes and for the country as a whole proved L. pomona. The main source of infection were the carrier pigs that excreted Leptospira organisms, and the infection at the industrial complexes came from the hybrid sows and boars imported from abroad for grading purposes. A biologically justified and economically expedient programme of immunoprophylaxis in the control of Leptospirosis was worked out, providing vaccination of replacement pigs and sows only, treatment taking place after impregnation. PMID- 1030873 CU - 88 TT - Vurkhu epizootologiiata na leptospirozata v promishlenite svinevudni kompleksi EA - A SO - Vet Med Nauki 1976;13(8):68-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77134371 AU - Cacciapuoti B TI - Co-antibodies in human leptospirosis. LA - Eng MH - Agglutinins/isolation & purification MH - Antibodies, Bacterial/*isolation & purification MH - Antibody Formation MH - Antibody Specificity MH - Antigens, Bacterial/isolation & purification MH - Complement Fixation Tests MH - Human MH - Leptospira/classification/immunology MH - Leptospirosis/*immunology PT - JOURNAL ARTICLE DA - 770527 DP - 1976 IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 495-509 SB - M CY - ITALY IP - 6 VI - 55 JC - AKG AA - Author EM - 7707 AB - Investigations concerning the co-antibodies formed in the course of human leptospirosis and the extractive antigens of leptospiras were reviewed. As a whole, the results concerning leptospira antigens point, next to antigens of serotype, to genus-specific and intertype antigens deeply seated in the cells. These cannot be identified by the MAL test, and therefore are not related to the co-agglutinins in human leptospirosis. The associations of co-antibodies in human leptospirotic sera were analyzed, using the MAL and CF tests performed with 20 pathogenic and water serotypes of leptospira. The results showed that in the course of human leptospirosis high titer co-antibodies are formed, both agglutinating and complement fixing, variably associated for one or more serotype antigens not belonging to the infecting strain. The various biological interpretations of the phenomenon were discussed and the hypothesis of antigenic changes of leptospira strains in vivo as well as in vitro was discussed, as a determining factor in the formation co-antibodies in leptospirosis. PMID- 1023889 SO - Boll Ist Sieroter Milan 1976;55(6):495-509 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 77103665 AU - Halat Z AU - Korczynska A AU - Ksinski J TI - [Leptospirosis outbreak in the Wroclaw Province in 1974] LA - Pol MH - Animal MH - Animals, Domestic MH - Disease Outbreaks/*epidemiology MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Male MH - Poland PT - JOURNAL ARTICLE DA - 770331 DP - 1976 IS - 0033-2100 TA - Przegl Epidemiol PG - 491-5 CY - POLAND IP - 4 VI - 30 JC - Q8T EM - 7705 PMID- 1013365 CU - 88 TT - Eidemia leptospiroz w wojewodztwie wroclawskim w roku 1974 EA - A SO - Przegl Epidemiol 1976;30(4):491-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 77092476 AU - Sebek Z AU - Rosicky B TI - Leptospira sorex-jalna antibodies in shrews in Bohemia. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Czechoslovakia MH - Leptospira/*immunology MH - Shrews/*immunology PT - JOURNAL ARTICLE DA - 770315 DP - 1976 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 200 CY - CZECHOSLOVAKIA IP - 3 VI - 23 JC - F2T EM - 7705 PMID- 1010488 SO - Folia Parasitol (Praha) 1976;23(3):200 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 77014671 AU - Velasco-Osorio R TI - [Serological survey on leptospirosis in bovines and swines in the state of Veracruz] LA - Spa MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - English Abstract MH - Leptospirosis/epidemiology/*veterinary MH - Mexico MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 761203 DP - 1976 Jan-Mar IS - 0034-8384 TA - Rev Invest Salud Publica PG - 13-7 CY - MEXICO IP - 1 VI - 36 JC - SCY EM - 7701 PMID- 987608 CU - 88 TT - Estudio serologico sobre leptospirosis en bovinos y porcinos del Estado de Veracruz EA - A SO - Rev Invest Salud Publica 1976 Jan-Mar;36(1):13-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 77007586 AU - Kiktenko VS AU - Balashov NG AU - Rodina VN TI - Leptospirosis infection through insemination of animals. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Female MH - Hamsters MH - *Insemination MH - Insemination, Artificial MH - Leptospira/isolation & purification/pathogenicity MH - Leptospirosis/immunology/*transmission MH - Male MH - Rabbits MH - Semen/immunology/microbiology PT - JOURNAL ARTICLE DA - 761201 DP - 1976 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 207-13 SB - M CY - CZECHOSLOVAKIA IP - 2 VI - 21 JC - IEV AA - Author EM - 7701 AB - The semen of animals in spontaneous and experimental leptospirosis was investigated by bacteriological, immunological and biological methods. It has been found that pathogenic leptospirae (L. pomona, L. hebdomadis) are well preserved in the semen and in media used for its dilution. Leptospirae are eliminated with the semen. The initial strain of the agent was isolated from the semen and secretions of 6 out of 26 experimentally infected rabbits and 4 spontaneously recovered bulls (L. hebdomadis). Specific leptospiral antibodies appear in the semen of infected animals. The dynamics of the titre of these antibodies corresponds to the dynamics of the antibody titre in the blood. It is recommended to use the semen for the agglutination reaction. The application of semen infected with pathogenic leptospirae for artificial insemination causes the animals falling ill with leptospirosis accompanied by abortions, reduced fertility and stillbirths of rabbits. PMID- 987112 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1976;21(2):207-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 77007571 AU - Kiktenko VS AU - Balashov NG AU - Rodina VN TI - Leptospirosis infection through insemination of animals. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Formation MH - Cattle MH - Cattle Diseases/*transmission MH - Female MH - Hamsters MH - Insemination, Artificial/*veterinary MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/transmission/*veterinary MH - Male MH - Rabbits MH - Semen/immunology/microbiology PT - JOURNAL ARTICLE DA - 761203 DP - 1976 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 207-13 SB - M CY - CZECHOSLOVAKIA IP - 2 VI - 20 JC - IEV AA - Author EM - 7701 AB - The semen of animals in spontaneous and experimental leptospirosis was investigated by bacteriological, immunological and biological methods. It has been found that pathogenic leptospirae (L. pomona, L. hebdomadis) are well preserved in the semen and in media used for its dilution. Leptospirae are eliminated with the semen. The initial strain of the agent was isolated from the semen and secretions of 6 out of 26 experimentally infected rabbits and 4 spontaneously recovered bulls (L. hebdomadis). Specific leptospiral antibodies appear in the semen of infected animals. The dynamics of the titre of these antibodies corresponds to the dynamics of the antibody titre in the blood. It is recommended to use the sement for the agglutination reaction. The application of semen infected with pathogenic leptospirae for artificial insemination causes the animals falling ill with leptospirosis accompanied by abortions, reduced fertility and stillbirths of rabbits. PMID- 987101 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1976;20(2):207-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 77041822 AU - Mohn SF AU - Sandvik O TI - Serological investigations of leptospiral deoxyribonucleases. LA - Eng MH - Animal MH - Deoxyribonucleases/*metabolism MH - Dogs MH - Leptospira/classification/*enzymology MH - Serotyping PT - JOURNAL ARTICLE DA - 761223 DP - 1976 IS - 0044-605X TA - Acta Vet Scand PG - 354-8 CY - DENMARK IP - 3 VI - 17 JC - 27V EM - 7702 PMID- 983894 SO - Acta Vet Scand 1976;17(3):354-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 77022583 AU - Zeigler JA AU - Jones RH AU - Kubica K TI - Immunization against leptospirosis: vaccine trials with heat-killed whole cell and outer envelope antigens in hamsters. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Hamsters MH - Heat MH - Leptospira/*immunology MH - Leptospirosis/*prevention & control MH - Vaccination PT - JOURNAL ARTICLE DA - 761223 DP - 1976 TA - Bull Pan Am Health Organ PG - 126-30 CY - UNITED STATES IP - 2 VI - 10 JC - BSB AA - Author EM - 7702 AB - Heat-killed whole cell and outer envelope antigens prepared from homologous virulent and avirulent strains of Leptospira serotypes canicola and pomona were evaluated for protecting hamsters against experimental leptospirosis. The heat-killed bacterins proved at least as effective as the outer envelope antigens, or more so, in providing protection against death and infection, and they are easier and more economical to prepare. PMID- 974302 CU - 89 SO - Bull Pan Am Health Organ 1976;10(2):126-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 77022582 AU - Szyfres B TI - Leptospirosis as an animal and public health problem in Latin America and the Caribbean area. LA - Eng MH - Animal MH - Animals, Domestic MH - Cattle MH - Cattle Diseases/microbiology MH - *Developing Countries MH - Disease Outbreaks MH - Disease Reservoirs MH - Dogs MH - Health Surveys MH - Human MH - Latin America MH - Leptospira/isolation & purification MH - *Leptospirosis/microbiology/veterinary MH - *Public Health MH - Rats MH - Sheep MH - Sheep Diseases/microbiology MH - Swine MH - Swine Diseases/microbiology MH - Weil's Disease MH - West Indies PT - JOURNAL ARTICLE DA - 761223 DP - 1976 TA - Bull Pan Am Health Organ PG - 110-25 CY - UNITED STATES IP - 2 VI - 10 JC - BSB AA - Author EM - 7702 AB - As a major livestock disease, leptospirosis cuts significantly into the world's supply of animal protein through its consequences of abortion and calf mortality, retarded growth, and reduced milk production. Evidently, such losses have severe economic implications as well. The disease's impact has been somewhat diminished in the developed countries thanks to mechanization of rural activities, improved personal and environmental hygiene, and broad application of preventive measures, including the administration of bacterins, in domestic animals. Still, even in these circumstances it remains a serious problem. In the developing countries, in which large percentages of the population live in close contact with animals, the spread of infection is much greater. Moreover, the ecology of tropical and subtropical America--with its abundant rainfall, natural water courses, and high temperatures--is particularly favorable for the transmission of leptospires. In such conditions the human disease is a growing threat as well. The spread of leptospirosis, both in animals and man, is facilitated by the fact that inefection from many of the serotypes can exist without presenting serious clinical manifestations. Hence the importance of laboratory diagnosis. Systematic studies over time of serotype distribution, coupled with wide and improved surveillance, will be a key factor in bringing the disease under control. According to the limited seroepidemiologic data available, 3 to 18 per cent of the general human population, 2 to 32 per cent of those belonging to exposed occupational groups, and 10 to 50 per cent of patients with fever of unknown origin have leptospiral antibody. The most predominant serogroups are Icterohaemorrhagiae, Canicola, Pomona, Hebdomadis, and Bataviae. So far more than 50 serotypes, from 15 serogroups, have been isolated from man and animals in Latin America and the Caribbean area. PMID- 974301 CU - 89 SO - Bull Pan Am Health Organ 1976;10(2):110-25 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 77018279 AU - Kazarian AS TI - [Study of the resistance of rabbits immunized with combined vaccines to Brucella culture] LA - Rus MH - Animal MH - Bacterial Vaccines/*administration & dosage MH - Brucella/*pathogenicity MH - Brucella Vaccine/administration & dosage MH - Brucellosis/immunology MH - Immunity, Active MH - Leptospira/immunology MH - Pasteurella/immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 761203 DP - 1976 IS - 0044-4510 TA - Zh Eksp Klin Med PG - 33-7 CY - USSR IP - 2 VI - 16 JC - Y9J EM - 7701 PMID- 973499 TT - Ispytanie ustoichivosti assotsiirovanno immunizirovannykh krolikov k brutselleznoi kul'ture SO - Zh Eksp Klin Med 1976;16(2):33-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 76273157 AU - Hergt R TI - [The current situation of leptospiroses in the GDR] LA - Ger MH - English Abstract MH - Germany, East MH - Human MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 761029 DP - 1976 Jan IS - 0049-8610 TA - Z Gesamte Hyg PG - 71-3 CY - GERMANY, EAST IP - 1 VI - 22 JC - XUO EM - 7612 PMID- 960814 CU - 88 TT - Zur gegenwartigen Situation der Leptospirosen in der DDR EA - A SO - Z Gesamte Hyg 1976 Jan;22(1):71-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 76256613 AU - Munnich D AU - Lakatos M TI - Treatment of human leptospira infections with semicillin (ampicillin) or with amoxil (amoxycillin). LA - Eng MH - Adolescence MH - Adult MH - Amoxicillin/*therapeutic use MH - Ampicillin/*analogs & derivatives/*therapeutic use MH - Comparative Study MH - Drug Evaluation MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*drug therapy/microbiology MH - Male MH - Middle Age MH - Occupations MH - Serotyping MH - Time Factors PT - JOURNAL ARTICLE DA - 761101 DP - 1976 IS - 0009-3157 TA - Chemotherapy PG - 372-80 SB - M CY - SWITZERLAND IP - 6 VI - 22 JC - D15 AA - Author EM - 7612 AB - Ampicillin (Semicillin) and Amoxycillin (Amoxil) have a strong leptospirocidal effect in vitro and also in vivo. We have tested these drugs on 28 patients suffering from Leptospira infection. The patients generally received per os 3 g Ampicillin (Semicillin) or 2 g Amoxycillin (Amoxil) per day over a period of 6 days. In the groups treated with Ampicillin and Amoxycillin the average durations of fever during the treatment were 1.6 and 1.2 days, respectively. In the first group (Ampicillin) a 'second wave of fever' occurred in one case (5%) and in the second group (Amoxycillin), in 0% (as compared to 22% after treatment with benzylpenicillin). On the basis of our experiences, Ampicillin and Amoxycillin are strongly recommended for the treatment of human Leptospira infections. PMID- 954482 CU - 90 SO - Chemotherapy 1976;22(6):372-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 76236469 AU - Sebek Z AU - Wallner H AU - Sixl W AU - Kaaserer G AU - Valova M TI - Leptospiral antibodies in domestic animals in Tyrol. LA - Eng MH - Animal MH - Animals, Domestic/*immunology MH - Antibodies, Bacterial/*analysis MH - Austria MH - Cats/immunology MH - Cattle/immunology MH - Dogs/immunology MH - Goats/immunology MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - Sheep/immunology MH - Swine/immunology PT - JOURNAL ARTICLE DA - 761002 DP - 1976 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 15-23 CY - CZECHOSLOVAKIA IP - 1 VI - 23 JC - F2T AA - Author EM - 7611 AB - Results are presented of a serological examination of 1,547 domestic animals (cattle, pig, sheep, horse, goat, dog, cat) from 9 Tyrolian districts (Austria), performed in order to disclose the incidence of leptospirosis. Completely significant titres were domonstrated by means of the MAL test in the serotypes icterohaemorrhagiae or copenhageni, sorex-jalna, bratislava, sejroe and saxkoebing. In addition, antibodies were confirmed against L. bataviae, L. pomona, L. tarassovi and L. bulgarica, but the titres were insignificant. Of the animals examined, 7.2% gave positive reactions in titres of 1: 800 and above (for dogs and cats 1: 100 and more); positive reactions were obtained from 8.8% of cattle serum, 6.8% of pig-, 1.1% of sheep-, 3.3% of dog-, 18.2% of cat serum. A positive reaction was obtained with the serum of one out of the 9 horses examined, the sera of the two goats examined were negative. he percentage of positivity in animals from the individual districts ranged from 1.0 to 17.0, and variations were found also in the distribution of serotypes in the individual districts. The results indicate that the percentage of positivity in domestic animals from Tyrol decreases as the altitude of the localities increases. PMID- 950180 SO - Folia Parasitol (Praha) 1976;23(1):15-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 76246867 AU - Obiger G AU - Schonberg A TI - [Intracutaneous leptospirin test on swine within the framework of the examination of slaughtered animals and control of animal epidemics] LA - Ger MH - *Abattoirs MH - Animal MH - Antibody Formation MH - Leptospira/isolation & purification MH - Leptospira canicola/isolation & purification MH - Leptospirosis/immunology/*veterinary MH - Swine MH - Swine Diseases/*diagnosis/immunology PT - JOURNAL ARTICLE DA - 761001 DP - 1976 IS - 0303-6286 TA - Tierarztl Prax PG - 203-6 SB - M CY - GERMANY, WEST IP - 2 VI - 4 JC - VS4 EM - 7611 RO - M:BDS PMID- 948809 LR - 850301 TT - Der intrakutane Leptospirintest am Schwein im Rahmen der Schlachttieruntersuchung und der Tierseuchenbekampfung SO - Tierarztl Prax 1976;4(2):203-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 76251528 AU - Finn MA AU - Jones RH TI - Growth of saprophytic and pathogenic leptospira: evaluation of medium, temperature, inoculum, and cost. LA - Eng MH - Comparative Study MH - *Culture Media MH - Evaluation Studies MH - Leptospira/*growth & development/pathogenicity MH - Oleic Acids MH - Serum Albumin, Bovine MH - Species Specificity MH - Support, U.S. Gov't, Non-P.H.S. MH - Temperature PT - JOURNAL ARTICLE DA - 760925 DP - 1976 Jan TA - Appl Environ Microbiol PG - 134-7 SB - M CY - UNITED STATES IP - 1 VI - 31 JC - 6K6 EM - 7611 PMID- 942202 CU - 89 SO - Appl Environ Microbiol 1976 Jan;31(1):134-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 76223965 AU - Hykutake S AU - de Biasi P AU - Santa Rosa CA AU - Belluomni HE TI - [Epidemiological study on leptospirosis in Brazilian snakes] LA - Por MH - Animal MH - Brazil MH - English Abstract MH - Leptospira/*isolation & purification MH - Leptospirosis/*microbiology MH - Snakes/*microbiology PT - JOURNAL ARTICLE DA - 760901 DP - 1976 Jan-Feb IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 10-6 CY - BRAZIL IP - 1 VI - 18 JC - S9D EM - 7610 PMID- 935733 TT - Contribuicao ao estudo epidemilogico das leptosiroses em serpentes do Brasil EA - A SO - Rev Inst Med Trop Sao Paulo 1976 Jan-Feb;18(1):10-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 79180285 AU - Hanson LE AU - Tripathy DN AU - Mansfield ME TI - Evaluation of sera of leptospiral vaccinated cattle for brucella antibodies. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Bacterial Vaccines/*immunology MH - Brucella abortus/*immunology MH - Cattle MH - Cross Reactions MH - Leptospira/*immunology MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 790716 DP - 1976 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 107-13 CY - UNITED STATES IP - 80 JC - PY5 EM - 7909 PMID- 830040 CU - 91 SO - Proc Annu Meet U S Anim Health Assoc 1976;(80):107-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 76147034 AU - Gilmartin WG AU - Delong RL AU - Smith AW AU - Sweeney JC AU - De Lappe BW AU - Risebrough RW AU - Griner LA AU - Dailey MD AU - Peakall DB TI - Premature parturition in the California sea lion. LA - Eng MH - Abortion, Veterinary/microbiology MH - Adipose Tissue/analysis MH - Age Factors MH - Animal MH - DDE/analysis MH - Female MH - Fetus/microbiology MH - Labor, Premature/*veterinary MH - Leptospira/isolation & purification MH - Leptospirosis/veterinary MH - Liver/analysis MH - Male MH - Nematode Infections/veterinary MH - Nephritis, Interstitial/veterinary MH - Picornaviridae/isolation & purification MH - *Pinnipedia MH - Polychlorinated Biphenyls/analysis MH - Pregnancy MH - Support, U.S. Gov't, Non-P.H.S. MH - Trematode Infections/veterinary MH - Virus Diseases/veterinary PT - JOURNAL ARTICLE DA - 760602 DP - 1976 Jan IS - 0090-3558 TA - J Wildl Dis PG - 104-15 SB - M CY - UNITED STATES IP - 1 VI - 12 JC - KEM AA - Author EM - 7607 AB - Twenty percent of the California sea lion pups born on San Miguel Island die due to premature parturition. Specimens collected from premature-partus animals resulted in recovery of a virus, San Miguel Sea Lion Virus, indistinguishable from Vesicular Exanthema of Swine Virus, and Leptospira pomona from some of the premature cows and pups. The age range of 10 females delivering healthy pups in June was 10-14 years. With one exception, the ages in 10 aborting females was 6-8 years. The p,p'-DDE levels of the premature parturient cows' blubber and liver were 7.6 and 4.8 times greater, respectively, than corresponding tissue concentrations in the full-term animals. Polychlorinated biphenyls residues were 4.4 and 3.8 times greater in aborting animals' blubber and liver than in the same tissues of full- term sea lions. Premature-partus females had tissue imbalances of mercury, selenium, cadmium and bromine. Pathology, parasitology, serum enzyme and hormone results are also presented. These data suggest an interrelationship of disease agents and environmental contaminants as the cause of premature parturition. PMID- 815567 CU - 91 SO - J Wildl Dis 1976 Jan;12(1):104-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 79224768 AU - Ginebra Gonzalez O TI - [Leptospirosis. Serological study of an epidemic outbrake in the province of Camaguey] LA - Spa MH - Agricultural Workers' Diseases/*microbiology MH - Cuba MH - Disease Outbreaks/history MH - English Abstract MH - Female MH - History of Medicine, 20th Cent. MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/history/*microbiology MH - Male PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 790917 DP - 1976 Jan-Apr IS - 0375-0760 TA - Rev Cubana Med Trop PG - 33-8 SB - M CY - CUBA IP - 1 VI - 28 JC - RPX AA - Author EM - 7911 AB - A brief historical review of human leptospirosis up to 1972 in Cuba is made. Serological studies were made among sugar cane workers from the Army of Working Youth (EJT) during an epidemic leptospirosis outbreak at the Camguey province in 1973. Results of those studies are presented. The outbreak was due to several serotypes of Leptospira. Other works of the author as well as several reports obtained from specialized medical literature are compared. PMID- 802792 CU - 90 TT - Leptospirosis. Estudio serologico de un brote epidemico en la provincia de Camaguey. EA - A SO - Rev Cubana Med Trop 1976 Jan-Apr;28(1):33-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 78034828 AU - Popova EM AU - Stoianova NA TI - [Leptospirosis] LA - Rus MH - Animal MH - Disease Reservoirs MH - Human MH - Immunologic Techniques MH - Leptospira/immunology MH - Leptospirosis/epidemiology/*etiology/immunology MH - USSR PT - JOURNAL ARTICLE DA - 771229 DP - 1976 TA - Tr Inst Pastera PG - 13-32 CY - USSR VI - 46 JC - VZG EM - 7802 PMID- 801301 CU - 90 TT - Leptospirozy. SO - Tr Inst Pastera 1976;46:13-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 77095381 AU - Roch P AU - Sramkova L AU - Salak J TI - The agglutinating and immunofluorescent activities of antileptospiral antibodies of human sera and of immunoglobulins M and G. LA - Eng MH - Adult MH - Agglutination Tests MH - Antibodies, Bacterial/*analysis MH - Child MH - Convalescence MH - Fluorescent Antibody Technique MH - Human MH - IgG/*analysis MH - IgM/*analysis MH - Leptospira/*immunology MH - Leptospirosis/*immunology MH - Middle Age MH - Time Factors PT - JOURNAL ARTICLE DA - 770315 DP - 1976 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 341-52 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 21 JC - IEV AA - Author EM - 7705 AB - Microagglutinating and immunofluorescent activities of sera of nine patients with clinically diagnosed leptospirosis were investigated. L. grippotyphosa was found in seven patients, L. sejroe in one and L. icterohaemorrhagiae in one patient. The agglutinating activities of IgM approximated the activities of the whole sera. In five patients the agglutinating activities were found in IgG; in four of them two to three months after the onset of the disease, in one patients a month after its onset. In one patient only the activity of IgG reached the activity of IgM after six months. Immunofluorescent activity was found in IgG in eight patients two to five weeks after the onset of the disease. In seven of these patients the activity of IgG reached or exceeded the activity of IgM three to ten weeks after the onset of the disease. IFAT was found to be poorly specific because of high heterologous titres. In 5 out of 7 patients with L. grippotyphosa, heterologous IFAT titres were reduced or eliminated by carrying out the reaction with isolated IgM and IgG. However, in patients with L. icterohaemorrhagiae and with L. sejroe heterologous IFAT activity persisted in both IgM and IgG. The study points out the possibility of differentiating an early stage of the infection from convalescence. PMID- 796383 CU - 90 SO - J Hyg Epidemiol Microbiol Immunol 1976;21(3):341-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 77052443 AU - Roch P AU - Sramkova L AU - Salak J TI - The agglutinating and immunofluorescent activities of antileptospiral antibodies of human sera and of immunoglobulins M and G. LA - Eng MH - Adult MH - Agglutination MH - Antibodies, Viral/*analysis MH - Child MH - Fluorescent Antibody Technique MH - Human MH - IgG/*analysis MH - IgM/*analysis MH - Leptospira/*immunology MH - Leptospirosis/*immunology MH - Middle Age PT - JOURNAL ARTICLE DA - 770128 DP - 1976 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 341-52 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 21 JC - IEV AA - Author EM - 7703 AB - Microagglutinating and immunofluorescent activities of sera of nine patients with clinically diagnosed leptospirosis were investigated. L. grippotyphosa was found in seven patients, L. sejroe in one and L. icterohaemorrhagiae in one patient. The agglutinating activities of IgM approximated the activities of the whole sera. In five patients the agglutinating activities were found in IgG; in four of them two to three months after the onset of the disease, in one patient a month after its onset. In one patient only the activity of IgG reached the activity of IgM after six months. Immunofluorescent activity was found in IgG in eight patients two to five weeks after the onset of the disease. In seven of these patients the activity of IgG reached or exceeded the activity of IgM three to ten weeks after the onset of the disease. IFAT was found to be poorly specific because of high heterologous titres. In 5 out of 7 patients with L. grippotyphosa, heterologous IFAT titres were reduced or eliminated by carrying out the reaction with isolated IgM and IgG. However, in patients with L. icterohaemorrhagiae and with L. sejroe heterologous IFAT activity persisted in both IgM and IgG. The study points out the possibility of differentiating an early stage of the infection from convalescence. PMID- 792329 CU - 90 SO - J Hyg Epidemiol Microbiol Immunol 1976;21(3):341-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76236470 AU - Sebek Z AU - Kaaserer G AU - Sixl W AU - Wallner H AU - Valova M TI - Leptospiral antibodies in wild living animals from North Tyrol. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Austria MH - Carnivora/immunology MH - Deer/immunology MH - Foxes/immunology MH - Leptospira/*immunology MH - Mammals/*immunology MH - Mice/immunology MH - Microtinae/immunology MH - Rats/immunology MH - Sciuridae/immunology MH - Shrews/immunology PT - JOURNAL ARTICLE DA - 761002 DP - 1976 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 25-31 CY - CZECHOSLOVAKIA IP - 1 VI - 23 JC - F2T AA - Author EM - 7611 AB - The authors examined serologically 623 wild living animals (22 species) from North Tyrol for the incidence of leptospirosis. Positive reactions (MAL) in the titre 1: 100 and more were found in 4.5% of the animals examined; the serotypes concerned were these: icterohaemorrhagiae, sorex-jalna, castellonis or arboreae, grippotyphosa, bratislava, pomona, sejroe, saxkoebing. Positive reactions were obtained with the sera of Sorex araneus, Erinaceus europaeus, Putorius putorius, Vulpes vulpes, Cervus elaphus, Capreolus capreolus, Rupicapra rupicapra, Apodemus sp., Clethrionomys glareolus. The serotypes forming natural foci of leptospirosis in North Tyrol are these: sorex-jalna, grippotyphosa, bratislava, saxkoebing and, apparently, jalna. Synanthropic foci are formed by icterohaemorrhagiae or copenhageni and sejroe. PMID- 780229 CU - 90 SO - Folia Parasitol (Praha) 1976;23(1):25-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 76147041 AU - Hooshmand-Rad P AU - Maghami G TI - Leptospirosis in small mammals of Iran: I. Serologic tests and isolation of Leptospira hebdomadis from Apodemus sylvaticus. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Insectivora/immunology MH - Iran MH - Lagomorpha/immunology MH - Leptospira/*immunology/isolation & purification MH - Leptospirosis/microbiology/veterinary MH - Mammals/*immunology MH - Microtinae/*microbiology MH - Rodent Diseases/microbiology MH - Rodentia/immunology/*microbiology PT - JOURNAL ARTICLE DA - 760602 DP - 1976 Jan IS - 0090-3558 TA - J Wildl Dis PG - 34-8 SB - M CY - UNITED STATES IP - 1 VI - 12 JC - KEM AA - Author EM - 7607 AB - Leptospires of the hebdomadis sero-group and related to sejroe serotype, were isolated from the kidney of a vole (Apodemus sylvaticus) by direct culture as well as by animal inoculation. Sera of the vole from which leptospires were isolated, and serologic specimens from 1372 other small mammals, were negative for leptospiral agglutinins. PMID- 768531 CU - 90 SO - J Wildl Dis 1976 Jan;12(1):34-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 76245868 AU - Nicolescu M AU - Moldoveanu G TI - [Use of culture media with sheep serum for maintenance and isolation of Leptospira strains] LA - Rum MH - Animal MH - *Blood MH - *Culture Media MH - English Abstract MH - *Leptospira MH - Sheep PT - JOURNAL ARTICLE DA - 761002 DP - 1976 Jan-Mar IS - 0376-4494 TA - Rev Ig [Bacteriol] PG - 49-53 SB - M CY - ROMANIA IP - 1 VI - 21 JC - S7C AA - Author EM - 7611 AB - A study was carried out on the effects of a culture medium prepared with sheep serum inactivated at 68 degrees C on Leptospira cultures. Good results were obtained showing that the medium with sheep serum can be used for the cultivation of Leptospira in view of the preparation of antigens for microscopic agglutination and complement fixation. In experiments on the isolation of germs from organocultures and haemocultures the proportion of positive results obtained with sheep serum was smaller than with the media containing rabbit serum. PMID- 133448 CU - 92 TT - Folosirea mediilor de cultura cu ser de oaie pentru intretinerea si izolarea tulpinilor de leptospire EA - A SO - Rev Ig [Bacteriol] 1976 Jan-Mar;21(1):49-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 77032993 AU - Pupkevich-diamant IaS TI - [Certain indicators of enzymograms and their diagnostic value in leptospirosis and viral jaundice] LA - Rus MH - Alkaline Phosphatase/analysis MH - Aminotransferases/analysis MH - Diagnosis, Differential MH - Fructosediphosphate Aldolase/analysis MH - Hepatitis, Viral, Human/*complications MH - Human MH - Jaundice/*enzymology/etiology MH - Leptospirosis/*enzymology PT - JOURNAL ARTICLE DA - 761230 DP - 1976 IS - 0023-6748 TA - Lab Delo PG - 289-93 CY - USSR IP - 5 JC - KYU EM - 7702 PMID- 62088 CU - 95 TT - Nekotorye pokazateli fermentogramm i ikh diagnosticheskoe znachenie pri leptospiroznykh i virusnykh zheltukhakh SO - Lab Delo 1976;(5):289-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 77022303 AU - Gabay J AU - Tinelli R TI - [Study of a specific polyoside and a group antigen extracted from Leptospira biflexa patoc, patoc I strain] LA - Fre MH - Animal MH - Antigens, Bacterial/*analysis/isolation & purification MH - English Abstract MH - Epitopes MH - Glucosamine/analysis MH - Hemagglutination Tests MH - Human MH - Immunodiffusion MH - Leptospira/*immunology MH - Lipids/analysis MH - Monosaccharides/analysis MH - Polysaccharides, Bacterial/analysis MH - Rabbits MH - Species Specificity PT - JOURNAL ARTICLE DA - 770103 DP - 1976 IS - 0300-9084 TA - Biochimie PG - 827-35 SB - M CY - FRANCE IP - 7 VI - 58 JC - A14 AA - Author EM - 7702 AB - We extracted from L. biflexa patoc a fraction F, reacting in hemagglutination and ring tests with sera prepared against more than ten different serogroups. This fraction contains mainly a polysaccharide (65 per cent), the role of which was clearly demonstrated in the precipitation reaction with homologous antisera, through periodic oxidation; it also contains lipids (20 per cent) and proteins (10 per cent). We isolated from this fraction F, by Biogel column chromatography, 2 distinct antigens, one, F2, carrying the patoc- type specificity, the other, F 1B, a group specificity shared by many leptospira. These antigens differ not only immunogically, but also in their chemical composition. The type-specific antigen F2 contains mainly a polysaccharide composed of arabinose and glucosamine (possibly an immunodominant sugar). As for the group-specific fraction F 1B, its composition is more complex since lipids and proteins are also found with the polysaccharide. This antigen could therefore be a lipoglycoprotein. PMID- 61770 CU - 95 TT - Etude d'un polyoside specifique et d'un antigene de groupe extraits de Leptospira biflexa patoc, souche patoc I EA - A SO - Biochimie 1976;58(7):827-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76202447 AU - Hovind-Hougen K TI - Determination by means of electron microscopy of morphological criteria of value for classification of some spirochetes, in particular treponemes. LA - Eng MH - Borrelia/classification/*ultrastructure MH - Cell Wall/ultrastructure MH - Flagella/ultrastructure MH - Inclusion Bodies/ultrastructure MH - Leptospira/classification/*ultrastructure MH - Microscopy, Electron MH - Staining MH - Treponema/classification/*ultrastructure MH - Treponema pallidum/classification/ultrastructure PT - JOURNAL ARTICLE DA - 760802 DP - 1976 TA - Acta Pathol Microbiol Scand Suppl PG - 1-41 SB - M CY - DENMARK IP - 255 JC - 1O4 EM - 7609 PMID- 58539 CU - 95 SO - Acta Pathol Microbiol Scand Suppl 1976;(255):1-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 76196684 AU - Fowler GF TI - Letter: Dark-ground microscopy of stained leptospires. LA - Eng MH - Animal MH - Leptospira/*cytology MH - Microscopy MH - *Staining PT - JOURNAL ARTICLE DA - 760802 DP - 1976 Jan-Feb IS - 0048-0169 TA - N Z Vet J PG - 24 CY - NEW ZEALAND IP - 1-2 VI - 24 JC - OBZ EM - 7609 PMID- 58396 CU - 95 SO - N Z Vet J 1976 Jan-Feb;24(1-2):24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76148181 AU - Kozlovskaia EV AU - Sushkova NK TI - [Method of preservation of blood sera of patients with leptospirosis for the immunofluorescence, microagglutination and lysis tests] LA - Rus MH - Agglutination Tests MH - Blood Preservation/*methods MH - Fluorescent Antibody Technique MH - Hemolysis MH - Human MH - Leptospirosis/*blood/diagnosis PT - JOURNAL ARTICLE DA - 760602 DP - 1976 IS - 0023-6748 TA - Lab Delo PG - 25-6 CY - USSR IP - 1 JC - KYU EM - 7607 PMID- 56483 CU - 95 TT - Metod konservirovaniia syvorotok bol'nykh dlia reaktsii immunofliuorestsentsii mikroaggliutinatsii lizisa SO - Lab Delo 1976;(1):25-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76132934 AU - Vigovskii AI AU - Vinograd IA TI - [Geographic distribution of diseases with natural foci and an epizootologic-epidemiologic study of the western Ukraine] LA - Rus MH - Aedes MH - Animal MH - Arthropod Vectors MH - Brucellosis/epidemiology MH - Brucellosis, Bovine/epidemiology MH - Cattle MH - Communicable Diseases/*epidemiology MH - *Disease Reservoirs MH - *Disease Vectors MH - Encephalitis, Tick-Borne/epidemiology MH - Hemorrhagic Fevers, Viral/epidemiology MH - Human MH - Insect Vectors MH - Leptospirosis/epidemiology MH - Lymphocytic Choriomeningitis/epidemiology MH - Rickettsia Infections/epidemiology MH - Ticks MH - Ukraine PT - JOURNAL ARTICLE DA - 760430 DP - 1975 Dec IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 8-14 SB - M CY - USSR IP - 12 JC - Y9O EM - 7606 PMID- 1243605 CU - 88 TT - Geograficheskoe rasprostranenie prirodnoochagovykh boleznei i epizootologo-epidemiologicheskie issledovaniia na zapade Ukrainy SO - Zh Mikrobiol Epidemiol Immunobiol 1975 Dec;(12):8-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 76179974 AU - King SD AU - Urquhart AE TI - Laboratory investigations on four cases of leptospiral meningitis in Jamaica. LA - Eng MH - Adolescence MH - Case Report MH - Diagnosis, Differential MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - Meningitis/*diagnosis MH - Meningitis, Viral/diagnosis PT - JOURNAL ARTICLE DA - 760706 DP - 1975 Dec IS - 0043-3144 TA - West Indian Med J PG - 196-201 CY - JAMAICA IP - 4 VI - 24 JC - XN4 EM - 7608 PMID- 1224630 SO - West Indian Med J 1975 Dec;24(4):196-201 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 76156857 AU - Cinco M AU - Cociancich L TI - A suitable medium for the cultivation of halophilic leptospirae. LA - Eng MH - *Culture Media MH - Leptospira/*growth & development MH - Polysorbates MH - Seawater PT - JOURNAL ARTICLE DA - 760602 DP - 1975 Dec IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 553-5 SB - M CY - GERMANY, WEST IP - 4 VI - 233 JC - Y52 AA - Author EM - 7607 AB - Cultural studies were carried out on halophilic Leptospirae to find a medium permitting their optimal growth and being easily reproducible. Tween 80 albumin medium enriched with artificial sea water shows these characteristics. PMID- 1221681 LR - 761029 CU - 90 SO - Zentralbl Bakteriol [Orig A] 1975 Dec;233(4):553-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 76131274 AU - Liubashenko SIa AU - Kirianov EA AU - Dragomir AA AU - Matveeva AA AU - Sakharova PU TI - [Etiology and some problems of the epizootology of leptospirosis in animals] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Leptospirosis/epidemiology/*veterinary MH - Swine MH - Swine Diseases/*epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 760406 DP - 1975 Dec IS - 0042-4846 TA - Veterinariia PG - 54-7 CY - USSR IP - 12 JC - XCC EM - 7606 PMID- 1216497 CU - 88 TT - Etiologiia i nekotorye voprosy epizootologii leptospiroza u zhivotnykh SO - Veterinariia 1975 Dec;(12):54-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 76131273 AU - Malakhov IuA AU - Gushchin VN AU - Samokhvalov AP AU - Solov'eva VS AU - Shupliko AN TI - [Dissemination and etiological structure of leptospirosis of swine] LA - Rus MH - Animal MH - Leptospirosis/epidemiology/*veterinary MH - Swine MH - Swine Diseases/*epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 760406 DP - 1975 Dec IS - 0042-4846 TA - Veterinariia PG - 50-3 CY - USSR IP - 12 JC - XCC EM - 7606 PMID- 1216496 CU - 88 TT - Rasprostranenie i etiologicheskaia struktura leptospiroza svinei SO - Veterinariia 1975 Dec;(12):50-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 76130877 AU - Shenberg E AU - Lindenbaum I AU - Dikken H AU - Torten M TI - Isolation of a 'saprophytic' leptospiral serotype andamana from carrier rats in Israel. LA - Eng MH - Animal MH - Israel MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - *Rats MH - Rodent Diseases/*microbiology MH - Serotyping PT - JOURNAL ARTICLE DA - 760419 DP - 1975 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 395-8 SB - M CY - NETHERLANDS IP - 4 VI - 27 JC - WGJ AA - Author EM - 7606 AB - The first isolation of two leptospira strains belonging to the serotype andamana from the kidney of Rattus norvegicus is reported. A strain of this serotype has never before been isolated in the Middle East, nor from any rodent in any other part of the world. Its epidemiologic significance and the classification of this serotype as part of the saprophytic Biflexa species is discussed. PMID- 1216320 SO - Trop Geogr Med 1975 Dec;27(4):395-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 76095468 AU - Carter PL AU - Ryan TJ TI - New microtechnique for the leptospiral microscopic agglutination test. LA - Eng MH - Agglutination Tests/*methods MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial MH - Comparative Study MH - Diagnosis, Differential MH - Evaluation Studies MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 760305 DP - 1975 Dec TA - J Clin Microbiol PG - 474-7 SB - M CY - UNITED STATES IP - 6 VI - 2 JC - HSH AA - Author EM - 7605 AB - A new microtechnique has been developed for the detection of leptospiral antibodies in serum by the microscopic agglutination test. The test was set up in a microtiter transfer plate held in a transfer plate holder, resting on a transfer plate cover. Live leptospiral antigen was added and a second transfer plate cover was placed over the transfer plate during 2 h of incubation at 32 C. After incubation the bottom cover was removed and the complete unit was placed in a specially designed base plate containing microscope slides (50 by 75 mm). The serum/antigen mixture was ejected on to the microscope slides by means of a sharp tap. The agglutination was then read using a 10 X objective, 10 X eyepieces, and a dry, dark field condenser. PMID- 1206106 CU - 89 SO - J Clin Microbiol 1975 Dec;2(6):474-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 76086111 AU - Tripathy DN AU - Smith AR AU - Hanson LE TI - Immunoglobulins in cattle vaccinated with leptospiral bacterins. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Cattle/*immunology MH - IgG/analysis MH - IgM/analysis MH - Immunoglobulins/*analysis MH - Leptospira/growth & development/*immunology MH - Leptospira interrogans/growth & development/immunology MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 760220 DP - 1975 Dec IS - 0002-9645 TA - Am J Vet Res PG - 1735-6 SB - M CY - UNITED STATES IP - 12 VI - 36 JC - 40C AA - Author EM - 7604 AB - The growth-inhibition test was used to detect specific antibodies against Leptospira interrogans serotype hardjo in isolated immunoglobulin (IgG and IgM) fractions of serums from cattle vaccinated with leptospiral bacterins. The growth-inhibiting antibodies were detected mainly in the IgG class. Agglutinated clumps also occurred with the IgM fraction. The serums collected from cattle 4 months after vaccination were negative in the microscopic agglutination test. PMID- 1200444 SO - Am J Vet Res 1975 Dec;36(12):1735-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 76085615 AU - Beck AM TI - The public health implications of urban dogs. LA - Eng MH - Age Factors MH - Animal MH - *Animals, Domestic MH - Bites and Stings/etiology MH - Child MH - Child, Preschool MH - Dog Diseases/transmission MH - *Dogs MH - Ecology MH - Environmental Exposure MH - Group Structure MH - Human MH - Leptospirosis/etiology/veterinary MH - *Public Health MH - Rabies/etiology/veterinary MH - Social Behavior MH - Species Specificity MH - Toxocariasis/etiology/veterinary MH - United States MH - Urban Population MH - *Zoonoses PT - JOURNAL ARTICLE DA - 760209 DP - 1975 Dec IS - 0090-0036 TA - Am J Public Health PG - 1315-8 SB - A SB - M CY - UNITED STATES IP - 12 VI - 65 JC - 3XW EM - 7604 PMID- 1200193 CU - 90 SO - Am J Public Health 1975 Dec;65(12):1315-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76067840 AU - Torten M AU - Johnson RC AU - Kaattari S AU - Leung C AU - Benjamini E TI - Immune plasma-dependent cytotoxicity of immune and non-immune peripheral lymphoid cells for target cells coated with bacterial outer unit membrane. LA - Eng MH - Animal MH - Antigens, Bacterial MH - Cell Membrane/immunology/ultrastructure MH - Chickens/immunology MH - *Cytotoxicity Tests, Immunologic MH - Dogs MH - Erythrocytes/immunology/ultrastructure MH - Hemagglutination MH - Lectins MH - Leptospira interrogans/*immunology MH - Lymphocytes/*immunology/metabolism MH - Thymidine/metabolism PT - JOURNAL ARTICLE DA - 760220 DP - 1975 Dec IS - 0019-2805 TA - Immunology PG - 1093-102 SB - M CY - ENGLAND IP - 6 VI - 29 JC - GH7 AA - Author EM - 7604 AB - The development of a model system for use in the study of lymphoid cell cytotoxicity to bacterial membrane antigens was attempted. In this system 51 Cr-labelled chicken red blood target cells were coated with pieces of the outer unit membrane of leptospirae rather than with soluble antigens. Using the model system to study dog peripheral immune lymphoid cell cytotoxicity to coated target cells we found that both immune and non-immune lymphocytes are antibody dependent for the expression of their cytotoxicity. It was also found that the unit membrane preparation from leptospirae can serve as a good antigenic stimulant to immune dog lymphoid cells as measured by increased [3H]thymidine uptake. PMID- 1193683 SO - Immunology 1975 Dec;29(6):1093-102 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 76199474 AU - Jaroonvesama N AU - Viranuvatti V AU - Charoenlarp K TI - Coagulation studies in leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Blood Cell Count MH - Blood Coagulation Disorders/blood/*etiology MH - Blood Coagulation Factors/analysis MH - Blood Coagulation Tests MH - Blood Platelets MH - Disseminated Intravascular Coagulation/blood/etiology MH - Female MH - Gastrointestinal Hemorrhage/blood/etiology MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Time Factors PT - JOURNAL ARTICLE DA - 760802 DP - 1975 Dec IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 562-6 SB - M CY - THAILAND IP - 4 VI - 6 JC - UVN AA - Author EM - 7609 AB - Coagulation and serum F.D.P. studies in 10 leptospirosis patients (5, L. bataviae, 2, L. autumnalis, 2, L. australis, and 1, L. akiyami A.)showed prolongation of prothrombin time, partial thromboplastin time and thrombin clotting time, slight low platelet count, depletion of factor V and slightly high serum F.D.P. in only four cases. Four cases had bleeding and one case died because of severe haemorrhage but with only slight changes in coagulation factors and slightly high serum F.D.P. These findings suggested that the damage of capillary endothelium was more pronounced than the coagulopathy which may be due to liver cell damage. PMID- 1084021 CU - 90 SO - Southeast Asian J Trop Med Public Health 1975 Dec;6(4):562-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [96 medline neighbors] UI - 76094007 AU - Charon NW AU - Johnson RC AU - Muschel LH TI - Antileptospiral activity in lower-vertebrate sera. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antibody Specificity MH - Anura MH - *Blood Bactericidal Activity MH - Complement/physiology MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Muramidase/blood MH - Rana pipiens MH - Support, U.S. Gov't, P.H.S. MH - Turtles PT - JOURNAL ARTICLE DA - 760330 DP - 1975 Dec IS - 0019-9567 TA - Infect Immun PG - 1386-91 SB - M CY - UNITED STATES IP - 6 VI - 12 JC - GO7 AA - Author EM - 7605 AB - Normal serum from the painted turtle (Chrysemys picta), the snapping turtle (Chelydra serpentina), and the frog (Rana pipiens) were found to possess bactericidal activity towards Leptospira. Leptospires from both the parasitic and biflexa complexes were killed by these sera at high dilutions. This pattern differs from that of mammalian serum, as generally only the biflexa complex leptospires are killed by normal mammalian serum. The activity in C. picta serum was characterized as being complement dependent and not mediated by basic proteins. Because comple-inactivated C. picta serum regained leptospiricidal activity after the addition of fresh rabbit serum, antibody is also likely to participate in the killing activity. Further support that C. picta serum contained leptospiral antibodies was found by the detection of serotype-specific agglutinins. PMID- 1081972 CU - 89 SO - Infect Immun 1975 Dec;12(6):1386-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 76212478 AU - Kitaoka M AU - Fujikura T TI - Isolation of Icterohaemorrhagiae from Microtus monte belli trapped at the Nagaoka area, Niigata Prefecture in Japan. LA - Eng MH - Animal MH - Female MH - Guinea Pigs MH - Japan MH - Kidney/microbiology MH - Leptospira interrogans/*isolation & purification MH - Male MH - Microtinae/*microbiology MH - Rodentia/*microbiology PT - JOURNAL ARTICLE DA - 760901 DP - 1975 Dec TA - Int J Zoonoses PG - 100-4 SB - M CY - TAIWAN IP - 2 VI - 2 JC - GTK AA - Author EM - 7610 AB - Three strains of leptospira were isolated from field rodents on the occasion of scrub typhus survey on the Nagaoka, Kurojo, Kamikawanishi area, Niigata Prefecture in September 1961. Out of 10 Microtus montebelli 3 strains of leptospira by means of heart puncture in febrile stage from guinea pigs. They were identified as icterohaemorrhagiae by cross-agglutination-lysis and a cross absorption tests. It was the first report of icterohaemorrhagiae in Microtus montebelli in Japan. PMID- 776885 CU - 90 SO - Int J Zoonoses 1975 Dec;2(2):100-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 76166925 AU - Kitaoka M AU - Fujikura T TI - Isolation of Icterohaemorrhagiae from Microtus montebelli trapped at the Nagaoka area, Niigata Prefecture in Japan. LA - Eng MH - Animal MH - *Disease Vectors MH - Guinea Pigs MH - Japan MH - Leptospira interrogans/*isolation & purification MH - Microtinae/*parasitology MH - Rodentia/*parasitology PT - JOURNAL ARTICLE DA - 760706 DP - 1975 Dec TA - Int J Zoonoses PG - 100-4 SB - M CY - TAIWAN IP - 2 VI - 2 JC - GTK AA - Author EM - 7608 AB - Three strains of leptospira were isolated from field rodents on the occasion of scrub typhus survey on the Nagaoka, Kurojo, Kamikawanishi area, Niigata Prefecture in September 1961. Out of 10 Microtus montebelli 3 strains of leptospira by means of heart puncture in febrile stage from guinea pigs. They were identified as icterohaemorrhagiae by cross-agglutination-lysis and a cross absorption tests. It was the first report of icterohaemorrhagiae in Microtus montebelli in Japan. PMID- 770360 CU - 90 SO - Int J Zoonoses 1975 Dec;2(2):100-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 76192885 AU - Tsai CC TI - Passive hemagglutination test as a serodiagnostic tool for human leptospirosis. LA - Eng MH - Comparative Study MH - Epitopes MH - Hemagglutination Tests MH - Hemolytic Plaque Technique MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/immunology PT - JOURNAL ARTICLE DA - 760802 DP - 1975 Dec IS - 0371-7682 TA - Taiwan I Hsueh Hui Tsa Chih PG - 762-6 CY - TAIWAN IP - 12 VI - 74 JC - I6V EM - 7609 PMID- 58056 CU - 95 SO - Taiwan I Hsueh Hui Tsa Chih 1975 Dec;74(12):762-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 76076111 AU - Dietz A TI - [Diagnostic problems in a case of icterohemorrhagic leptospirosis] LA - Ita MH - Case Report MH - Diagnosis, Differential MH - Human MH - Jaundice/etiology MH - Male MH - Middle Age MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 760226 DP - 1975 Nov 21 IS - 0026-4806 TA - Minerva Med PG - 4213-4 SB - M CY - ITALY IP - 79 VI - 66 JC - N6M EM - 7604 PMID- 1196511 TT - Problemi diagnostici in un caso di leptospirosi ittero emorragica SO - Minerva Med 1975 Nov 21;66(79):4213-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 76030151 AU - Berger SA AU - Barza M TI - Letter: Rarity of leptospirosis in New England. LA - Eng MH - Adult MH - Human MH - Leptospirosis/*epidemiology/immunology MH - New England PT - JOURNAL ARTICLE DA - 751229 DP - 1975 Nov 20 IS - 0028-4793 TA - N Engl J Med PG - 1106-7 SB - A SB - M CY - UNITED STATES IP - 21 VI - 293 JC - NOW EM - 7602 PMID- 1178034 CU - 88 SO - N Engl J Med 1975 Nov 20;293(21):1106-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 76156963 AU - Kornilova GV AU - Raikhlin MI AU - Iastrebov VK AU - Shaiman MS AU - Egorova LS TI - [New findings concerning the spread of natural foci of infection in the transpolar region of eastern Siberia] LA - Rus MH - Animal MH - Arboviruses/isolation & purification MH - Encephalitis, Tick-Borne/epidemiology MH - English Abstract MH - Leptospirosis/epidemiology MH - Rickettsia Infections/epidemiology MH - Rodent Diseases/*epidemiology MH - Siberia MH - Ticks/microbiology MH - Toxoplasmosis, Animal/epidemiology MH - Tularemia/epidemiology MH - West Nile Fever/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 760602 DP - 1975 Nov IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 96-100 SB - M CY - USSR IP - 11 JC - Y9O AA - Author EM - 7607 AB - New materials are presented on the presence of the foci of anthropozoonozes in the Extreme North. For the first time there was established the existence in the subarctic tundra of the Taimyr peninsula of the arbovirus foci of the tick-borne encephalitis complex. A virus of the tick-borne encephalitis complex was isolated in 1973 from the gamasida ticks Haemogamasus ambulans Thorel. and Hirstionyssus isabellinus Oudms. and the nests of the Siberian lemming Lemmus lemmus L. This pointed to the existence in the Transpolar region of the foci or arboviruses in the nest-hole biocenoses of the lemmings outside the bird colonies. Cultures of tularemia bacilli (which proved the etiology of the epizootic among the lemmings observed in 1973 and also the presence of the lemming natural foci of tularemia and their combination with the arbovirus foci) were isolated from the lemmings at the same territory. The results of serological examination of the local population and of the animals pointed to the circulation in the Transpolar region of the causative agents of leptospirosis, toxoplasmosis, Q-fever and of the Asian tick-borne rickettsiosis. PMID- 1243720 CU - 90 TT - Novye dannye o rasprostranenii prirodnoochagovykh infektsii v Zapoliar'e Vostochnoi Sibiri EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1975 Nov;(11):96-100 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 76132810 AU - Cinco M AU - Tamaro M AU - Cociancich L TI - Taxonomical, cultural and metabolic characteristics of halophilic leptospirae. LA - Eng MH - Animal MH - Bicarbonates MH - Catalase/analysis MH - Coagulase/analysis MH - Copper MH - Fishes/microbiology MH - Leptospira/*classification/growth & development/metabolism MH - Lipase/analysis MH - Polysorbates MH - Seawater MH - Serotyping MH - Sodium/metabolism MH - Sulfates MH - Urease/analysis MH - Water Microbiology PT - JOURNAL ARTICLE DA - 760419 DP - 1975 Nov IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 400-5 SB - M CY - GERMANY, WEST IP - 3 VI - 233 JC - Y52 AA - Author EM - 7606 AB - Four strains of leptospirae were isolated from the sea and studied from a serological and metabolic point of view. These strains did not differ from saprophytic leptospirae except for their Na+ dependence. PMID- 1240711 CU - 90 SO - Zentralbl Bakteriol [Orig A] 1975 Nov;233(3):400-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 76063911 AU - Livermore BP AU - Johnson RC TI - The lipids of four unusual non-pathogenic host-associated spirochetes. LA - Eng MH - Animal MH - Butyrates/metabolism MH - Fatty Acids/analysis MH - Feces/microbiology MH - Glycolipids/analysis MH - Human MH - Lipids/*analysis MH - Mouth/microbiology MH - Phospholipids/analysis MH - Spirochaeta/*analysis/classification/metabolism MH - Support, U.S. Gov't, P.H.S. MH - Swine MH - Valerates/metabolism PT - JOURNAL ARTICLE DA - 760301 DP - 1975 Nov IS - 0008-4166 TA - Can J Microbiol PG - 1877-80 SB - M CY - CANADA IP - 11 VI - 21 JC - CJ3 AA - Author EM - 7604 AB - The lipid compositions of two spirochetes isolated from the human oral cavity and two isolated from pig feces were examined. These isolates were unusual in that they did not require long-chain fatty acids for growth, as do the other host-associated spirochetes, but rather required isobutyric and valeric acids. Therefore, they could be cultured in a medium free of serum or fatty acid - albumin supplements. The major fatty acids synthesized were normal and iso fatty acids with 14 and 16 carbons. No unsaturated fatty acids were detected, nor were chain lengths longer than 16 carbons. The major complex lipids found were monogalactosyl diglyceride, phosphatidyl glycerol, and bis- phosphatidyl glycerol. Nitrogenous phospholipids, present in Treponema and Leptospira, were not synthesized by these novel strains. The data indicate an intermediate position of these isolates between Treponema and free-living Spriochaeta. PMID- 1238163 CU - 85 SO - Can J Microbiol 1975 Nov;21(11):1877-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 76183063 AU - Bolotskii IA TI - [Effect of some antibiotics and chemotherapeutic preparations on Leptospira in vitro] LA - Rus MH - Anti-Infective Agents/*pharmacology MH - Antibiotics/*pharmacology MH - Drug Combinations MH - Drug Screening MH - English Abstract MH - Leptospira/*drug effects MH - Microbial Sensitivity Tests MH - Time Factors PT - JOURNAL ARTICLE DA - 760706 DP - 1975 Nov IS - 0003-5637 TA - Antibiotiki PG - 1011-4 SB - M CY - USSR IP - 11 VI - 20 JC - 6GC AA - Author EM - 7608 AB - It was shown in vitro with the method of successive serial dilutions that polymyxin M, thilan, streptomycin, neomycin, sodium levomycetin succinate, brilliant green, tripaphlavin, azidin, aminoacrichin, and novarsenol had the most pronounced bactericidal effect on Leptospira. Combination of the antibiotics or the chemotherapeutics apart from azidin and tripaphlavin did not increase the bactericidal effect as compared to their use alone. The clinical and collection strains of Leptospira had the same sensitivity to the substances tested. The above drugs should be tested on animals with leptospirosis. PMID- 1225166 CU - 90 TT - Vliianie nekotorykh antibiotikov i khimiopreparatov na leptospir in vitro EA - A SO - Antibiotiki 1975 Nov;20(11):1011-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 76153783 AU - Lyra LG AU - Reboucas G AU - Fontes AF AU - Barbosa M AU - Peixinho A AU - Barbosa E TI - [Australia antigen in acute viral hepatitis and leptospirosis in Salvador, Bahia] LA - Por MH - Adolescence MH - Adult MH - Aged MH - Brazil MH - Child MH - Child, Preschool MH - Comparative Study MH - English Abstract MH - Hepatitis A/epidemiology/*immunology MH - Hepatitis B/epidemiology/immunology MH - *Hepatitis B Antigens/analysis MH - Human MH - Infant MH - Leptospirosis/*epidemiology/immunology MH - Middle Age PT - JOURNAL ARTICLE DA - 760525 DP - 1975 Nov-Dec IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 361-7 CY - BRAZIL IP - 6 VI - 17 JC - S9D EM - 7607 PMID- 1219977 CU - 88 TT - Antigeno Australia em hepatites agudas a virus e leptospiroses em Salvador, Bahia EA - A SO - Rev Inst Med Trop Sao Paulo 1975 Nov-Dec;17(6):361-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 76156928 AU - Gol'denshtein ZA TI - [The epidemiology and clinical picture of icterohemorrhagic leptospirosis in the Krasnodar area] LA - Rus MH - Adolescence MH - Adult MH - Child MH - Human MH - Russia MH - Weil's Disease/*diagnosis/epidemiology PT - JOURNAL ARTICLE DA - 760602 DP - 1975 Nov IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 121-2 SB - M CY - USSR IP - 11 JC - Y9O EM - 7607 PMID- 130766 CU - 92 TT - K epidemiologii i klinike ikterogemorragicheskogo leptospiroza v Krasnodarskom krae SO - Zh Mikrobiol Epidemiol Immunobiol 1975 Nov;(11):121-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 76039738 AU - Liceras de Hidalgo J TI - [Leptospirosis in San Martin, Peru] LA - Spa MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - English Abstract MH - Leptospirosis/epidemiology/*veterinary MH - Peru MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 760117 DP - 1975 Nov IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 410-21 CY - UNITED STATES IP - 5 VI - 79 JC - AGG EM - 7603 PMID- 126691 CU - 92 TT - Leptospirosis en San Martin, Peru EA - A SO - Bol Oficina Sanit Panam 1975 Nov;79(5):410-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 76045979 AU - Smith BP AU - Armstrong JM TI - Fatal hemolytic anemia attributed to leptospirosis in lambs. LA - Eng MH - Anemia, Hemolytic/etiology/pathology/*veterinary MH - Animal MH - Female MH - Kidney/pathology MH - *Leptospira interrogans MH - Leptospirosis/complications/pathology/*veterinary MH - Male MH - Sheep MH - *Sheep Diseases/etiology/pathology PT - JOURNAL ARTICLE DA - 760123 DP - 1975 Oct 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 739-41 SB - M CY - UNITED STATES IP - 8 VI - 167 JC - HAV EM - 7603 PMID- 1184434 SO - J Am Vet Med Assoc 1975 Oct 15;167(8):739-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 76106187 AU - Komardina MP AU - Malakhov IuA AU - Trykanova IuG TI - [Selection of antibiotics for treating animal carriers of Leptospira] LA - Rus MH - Animal MH - Antibiotics/*therapeutic use MH - Carrier State/*drug therapy MH - Drug Screening MH - Hamsters MH - Listeria Infections/*drug therapy PT - JOURNAL ARTICLE DA - 760311 DP - 1975 Oct IS - 0042-4846 TA - Veterinariia PG - 45-7 CY - USSR IP - 10 JC - XCC EM - 7605 PMID- 1209921 TT - Podbor antibiotikov dlia lecheniia zhivotnykh-leptospironositelei SO - Veterinariia 1975 Oct;(10):45-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 76093761 AU - Albert FW AU - Schultz R AU - Christ B TI - [Leptospirosis grippotyphosa with jaundice, acute renal failure and paraproteinemia (author's transl)] LA - Ger MH - Ampicillin/therapeutic use MH - Case Report MH - English Abstract MH - Hemodialysis MH - Hepatomegaly/etiology MH - Human MH - Jaundice/*etiology MH - Kidney/pathology MH - Kidney Failure, Acute/*etiology/therapy MH - Leptospirosis/*complications MH - Liver/pathology MH - Male MH - Middle Age MH - Paraproteinemias/*etiology PT - JOURNAL ARTICLE DA - 760330 DP - 1975 Oct TA - Immun Infekt PG - 225-31 SB - M CY - GERMANY, WEST IP - 5 VI - 3 JC - GH1 EM - 7605 PMID- 1205496 CU - 89 TT - Leptospirosis grippotyphosa mit ikterus, akutem Nierenversagen und Paraproteinamie EA - A SO - Immun Infekt 1975 Oct;3(5):225-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 76064017 AU - Higgins R AU - Cayouette P AU - Cousineau JG TI - [Leptospirosis in dairy cattle: serological survey in the province of Quebec] LA - Fre MH - Animal MH - Cattle MH - Cattle Diseases/*immunology MH - English Abstract MH - Female MH - Leptospirosis/immunology/*veterinary MH - Quebec PT - JOURNAL ARTICLE DA - 760209 DP - 1975 Oct IS - 0008-5286 TA - Can Vet J PG - 304-7 CY - CANADA IP - 10 VI - 16 JC - CLS EM - 7604 PMID- 1192340 TT - La leptospirose chez les bovins laitiers, enquete serologique dans la province de Quebec EA - A SO - Can Vet J 1975 Oct;16(10):304-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76024614 AU - Shotts EB Jr AU - Andrews CL AU - Harvey TW TI - Leptospirosis in selected wild mammals of the Florida panhandle and southwestern Georgia. LA - Eng MH - Animal MH - Carnivora MH - Deer MH - Florida MH - Georgia MH - Leptospirosis/epidemiology/immunology/*veterinary MH - *Mammals MH - Mice MH - Opossums MH - Rats MH - Rodent Diseases/immunology MH - Sciuridae MH - Shrews MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 751229 DP - 1975 Oct 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 587-9 SB - M CY - UNITED STATES IP - 7 VI - 167 JC - HAV AA - Author EM - 7602 AB - A group of 144 wild mammals, including white-tailed deer, cottontail rabbits, fox squirrels, gray squirrels, raccoons, opossums, a bobcat, and various small rodents was examined for cultural or serologic evidence of leptospiral infection. Leptospires were isolated from 1 of 25 rabbits, 1 of 27 fox squirrels, 1 of 26 gray squirrels, 4 of 18 mice and rats, 8 of 21 raccoons, 7 of 17 opossums, and a bobcat. Isolations were not made from 6 deer examined. Serotypes isolated were Leptospira interrogans, serotype grippotyphosa and L interrogans, serotype ballum. New host-serotype relationships were noticed in the following instances: bobcat: grippotyphosa, and gray squirrel: ballum. These studies further confirm the occurrence of grippotyphosa in the fox squirrel. Serologic response in these animals did not necessarily correlate with isolations, although some relationship was noticed in raccoons and opossums. PMID- 1176352 CU - 88 SO - J Am Vet Med Assoc 1975 Oct 1;167(7):587-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76218085 AU - Kitaoka M AU - Mori M AU - Arimitsu Y TI - In vitro and in vivo effects of kasugamycin on Leptospira icterohaemorrhagiae. LA - Eng MH - Animal MH - Antibiotics/*pharmacology MH - Antibiotics, Aminoglycoside/*pharmacology/therapeutic use MH - Guinea Pigs MH - Leptospira interrogans/*drug effects MH - Weil's Disease/*drug therapy PT - JOURNAL ARTICLE DA - 760823 DP - 1975 Oct-Dec IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 285-90 SB - M CY - JAPAN IP - 5-6 VI - 28 JC - KLZ EM - 7610 PMID- 1047116 CU - 87 SO - Jpn J Med Sci Biol 1975 Oct-Dec;28(5-6):285-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 76024617 AU - Bigler WJ AU - Jenkins JH AU - Cumbie PM AU - Hoff GL AU - Prather EC TI - Wildlife and environmental health: raccoons as indicators of zoonoses and pollutants in southeastern United States. LA - Eng MH - Adipose Tissue/analysis MH - Animal MH - Carnivora MH - Cesium Radioisotopes/analysis MH - Deer MH - Encephalitis Virus, Venezuelan Equine/isolation & purification MH - Encephalomyocarditis Virus/isolation & purification MH - *Environmental Health MH - *Environmental Pollutants MH - Florida MH - Georgia MH - Mercury/analysis MH - Pesticide Residues/analysis MH - Rabbits MH - *Raccoons/microbiology MH - Salmonella Infections, Animal/epidemiology MH - Sciuridae MH - South Carolina MH - Strontium Radioisotopes/analysis MH - Water Microbiology MH - *Zoonoses PT - JOURNAL ARTICLE PT - REVIEW DA - 751229 DP - 1975 Oct 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 592-7 SB - M CY - UNITED STATES IP - 7 VI - 167 JC - HAV AA - Author EM - 7602 AB - Inasmuch as terrestrial fauna are an integral part of our natural environment and are directly exposed to disease and pollutants, it follows that certain wild populations could serve to detect subtle alterations within ecosystems. A collection of studies on raccoons is presented to stimulate other researchers to develop the potential of our wildlife resources as monitors of environmental health. Raccoons have been used as serologic sentinels for St Louis encephalitis and Venezuelan equine encephalomyelitis. Studies suggest that the raccoon may be used as an indicator of leptospirosis, tularemia, and some enteric bacteria and viruses. Base line surveys have defined (1) residue levels of organochlorine and organophosphate compounds and (2) body burdens of mercury, cesium-137, and strontium-90. Physiologic responses, parasite burdens, and reproductive processes are also considered as measures that may reflect pertinent information about environmental health. RF - 54 PMID- 170239 CU - 93 SO - J Am Vet Med Assoc 1975 Oct 1;167(7):592-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [25 medline neighbors] UI - 76060756 AU - Breznak JA AU - Canale-Parola E TI - Morphology and physiology of Spirochaeta aurantia strains isolated from aquatic habitats. LA - Eng MH - Aerobiosis MH - Amino Acids/metabolism MH - Anaerobiosis MH - Antibiotics/pharmacology MH - Carbohydrates/metabolism MH - *Chemotaxis MH - Cytosine Nucleotides/analysis MH - Drug Resistance, Microbial MH - DNA, Bacterial/analysis MH - Fermentation MH - Glucose/metabolism MH - Guanine Nucleotides/analysis MH - Microscopy, Electron MH - Nitrogen/metabolism MH - Phylogeny MH - Spirochaeta/*classification/cytology/physiology MH - Vitamins/metabolism MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 760123 DP - 1975 Sep 30 IS - 0302-8933 TA - Arch Microbiol PG - 1-12 SB - M CY - GERMANY, WEST IP - 1 VI - 105 JC - 7YN AA - Author EM - 7603 AB - 1. Seven strains of Spirochaeta aurantia were isolated from pond and swamp water by means of a selective technique which utilized the ability of these organisms to move through bacterial filters and to diffuse through agar media. Although most of the isolations were accomplished when enrichment media low in carbohydrates were used, all seven strains were found to be exclusively saccharolytic. 2. The isolates could be divided into two groups on the basis of cell morphology: a loosely coiled group, and a tightly coiled group with markedly smaller wave length and wave apmlitude. Spirochetes of the latter group possessed a slightly lower GC content in their DNA. The isolates were facultative anaerobes, synthesized carotenoid pigments which conferred an orange color to aerobic colonies, and utilized a variety of carbohydrates--but not amino acids--as energy sources. Exogenous thiamine was required by six isolates tested, riboflavin by four, and biotin by one. The major products of glucose fermentation were acetate, ethanol, CO2 and H2. Growth of the isolates was inhibited by a variety of antibiotics. Determinations of GC contents of DNA showed that strains of S. aurantia are phylogenetically distant from spirochetes classified in the genera Treponema and Leptospira. 3. S. aurantia populations inoculated in the center of agar medium plates migrated in the form of growth rings toward the periphery of the plates. The rate of migration of glucose-utilizing rings was greatest at low glucose concentrations (e.g., 0.02 g/100 ml). It was concluded that migration of cells present in these rings was mainly due to a chemotactic response to glucose which served both as the attractant and the substrate. Chemotaxis of S. aurantia toward glucose may be used as a selective factor in isolating this bacterium from natural environments. 4. The subspecific epithet stricta is proposed to recognize, taxonomically, the tightly coiled strains of S. aurantia. PMID- 1190952 CU - 90 SO - Arch Microbiol 1975 Sep 30;105(1):1-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 76146388 AU - Gear JH TI - Medical aspects of some zoonoses. LA - Eng MH - Animal MH - Chlamydia Infections MH - Disease Reservoirs MH - Leptospirosis MH - *Public Health MH - Rickettsia Infections MH - South Africa MH - Trypanosomiasis, African MH - Virus Diseases MH - *Zoonoses PT - JOURNAL ARTICLE DA - 760518 DP - 1975 Sep TA - J S Afr Vet Assoc PG - 221-5 SB - M CY - SOUTH AFRICA IP - 3 VI - 46 JC - JZH EM - 7607 PMID- 1243682 CU - 89 SO - J S Afr Vet Assoc 1975 Sep;46(3):221-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 77258681 AU - Cortina Greus P AU - Hernandez Galve A TI - [Results of a survey on leptospirosis of rice fields workers] LA - Spa MH - Adolescence MH - Adult MH - Aged MH - Agricultural Workers' Diseases/*epidemiology MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Rice MH - Spain PT - JOURNAL ARTICLE DA - 771028 DP - 1975 Sep IS - 0034-8899 TA - Rev Sanid Hig Publica (Madr) PG - 825-36 CY - SPAIN IP - 9 VI - 49 JC - T41 EM - 7712 PMID- 1236205 CU - 88 TT - Resultados de una encuesta de leptospirosis en trabajadores de arrozales. EA - A SO - Rev Sanid Hig Publica (Madr) 1975 Sep;49(9):825-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76180203 AU - Mampel E AU - Koall W AU - Ganzert G TI - [Acute hemodialysis in internal medicine emergency therapy] LA - Ger MH - Adolescence MH - Adult MH - Amanita MH - Carbon Tetrachloride Poisoning/therapy MH - Case Report MH - Child MH - Diabetic Angiopathies/therapy MH - *Emergencies MH - Female MH - *Hemodialysis MH - Human MH - Kidney Failure, Acute/etiology/therapy MH - Leptospirosis/therapy MH - Liver Diseases/therapy MH - Male MH - Middle Age MH - Mushroom Poisoning/therapy MH - Porphyria/therapy MH - Pregnancy MH - Pregnancy Complications/therapy MH - Septicemia/therapy PT - JOURNAL ARTICLE DA - 760706 DP - 1975 Sep 1 IS - 0044-2542 TA - Z Gesamte Inn Med PG - 175-6 contd SB - M CY - GERMANY, EAST IP - 17 VI - 30 JC - XUY EM - 7608 PMID- 1224728 CU - 90 TT - Akute Hamodialyse in der internistischen notfallstherapie SO - Z Gesamte Inn Med 1975 Sep 1;30(17):175-6 contd ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 76171867 AU - Ramachandran S TI - Electrocardiographic abnormalities in leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Electrocardiography MH - Heart/*physiopathology MH - Human MH - Leptospirosis/*physiopathology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 760706 DP - 1975 Sep IS - 0022-5304 TA - J Trop Med Hyg PG - 210-3 SB - M CY - ENGLAND IP - 9 VI - 78 JC - KAV AA - Author EM - 7608 AB - Electrocardiographic abnormalities occurred in 46 per cent of cases uith leptospirosis. Although the individual changes noted do not appear to be of importance, they indicate that sub-clinical cardiac involvement does occur in a significant proportion of the patients. The abnormalities observed include disorders in cardiac rhythm and changes in the P-QRS-T complexes, probably resulting from direct myocardial involvement or from a changing milieu interior. While serial tracings are indicated in patients with acute renal failure of the oliguric variety, repeated tracings may detect more definitely changing patterns which indicate the presence of cardiac involvement in patients with other presentations of the disease. PMID- 1223330 SO - J Trop Med Hyg 1975 Sep;78(9):210-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 76131511 AU - Bolotskii IA AU - Korshunova LN AU - Shiliakin VK AU - Davydenko RF TI - [Dynamics of antibody formation in swine with leptospirosis] LA - Rus MH - Animal MH - Antibodies, Bacterial/analysis MH - *Antibody Formation MH - Leptospirosis/immunology/*veterinary MH - Swine MH - Swine Diseases/*immunology MH - Time Factors PT - JOURNAL ARTICLE DA - 760427 DP - 1975 Sep IS - 0042-4846 TA - Veterinariia PG - 50-2 CY - USSR IP - 9 JC - XCC EM - 7606 PMID- 1216664 CU - 90 TT - Dinamika obrazovaniia antitel u svinei pri leptospiroze SO - Veterinariia 1975 Sep;(9):50-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 76084166 AU - Takashima I AU - Yanagawa R TI - Immunizing effects of structural components of Leptospira icterohaemorrhagiae. LA - Eng MH - Animal MH - *Antigens, Bacterial MH - Bacterial Proteins/*immunology MH - *Bacterial Vaccines MH - Carrier State/prevention & control MH - Cell Wall/analysis/*immunology MH - Comparative Study MH - Freeze Drying MH - Guinea Pigs MH - Heat MH - Immunization MH - Injections, Intradermal MH - Leptospira interrogans/analysis/*immunology MH - Muramic Acids/analysis MH - Subcellular Fractions MH - Weil's Disease/*prevention & control PT - JOURNAL ARTICLE DA - 760301 DP - 1975 Sep IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 93-8 SB - M CY - GERMANY, WEST IP - 1 VI - 233 JC - Y52 AA - Author EM - 7604 AB - The protective attributes of the structural components of Leptospira icterohaemorrhagiae strain Shibaura were examined. Guinea pigs were immunized with the outer envelope, the cell wall, the type-specific main antigen, and the protein constituent of the outer envelope respectively. Of the 4 preparations, the outer envelope, the cell wall and the type-specific main antigen showed a considerable protective effect in this order. The protein constituent of the outer envelope was less effective. Immunization with 200 mug of the outer envelope protected guinea pigs from lethal infection but no completely from the renal carrier state. The rate of protection from renal leptospirosis by the preparations of leptospiral components and lyophilized whole cells was always inferior to the survivor rate. PMID- 1202875 CU - 90 SO - Zentralbl Bakteriol [Orig A] 1975 Sep;233(1):93-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 76087411 AU - Dobson KJ AU - Davos DE TI - Leptospiral titres in pigs after vaccination. LA - Eng MH - Agglutinins/analysis MH - Animal MH - Antibodies, Bacterial/*analysis MH - Female MH - Immunization, Secondary/veterinary MH - Leptospira/*immunology MH - Leptospirosis/prevention & control/*veterinary MH - Swine MH - Swine Diseases/*prevention & control MH - Time Factors MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 760219 DP - 1975 Sep IS - 0005-0423 TA - Aust Vet J PG - 443-4 SB - M CY - AUSTRALIA IP - 9 VI - 51 JC - 9IE AA - Author EM - 7604 AB - Two groups of 8 pigs were vaccinated and given a booster vaccination 6 weeks later each with a commercial dual L. pomona and L. tarassovi killed vaccine. Serum from bloods collected before and up to 30 weeks after vaccination had agglutinating antibodies only after the 0ooster vaccination and then only with 1 vaccine. Titres persisted less than 8 weeks when tested against L. pomona but up to 16 weeks when tested against L. tarassovi at the 1:300 dilution and up to 20 weeks at the 1:100 dilution. PMID- 1200937 CU - 90 SO - Aust Vet J 1975 Sep;51(9):443-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 76084187 AU - Zamora J AU - Kruze J AU - Riedemann S TI - [Leptospirosis in domestic animals in the south of Chile. Serological study] LA - Spa MH - Animal MH - *Animals, Domestic MH - Artiodactyla MH - Cattle MH - Chile MH - Dogs MH - English Abstract MH - Horses MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 760221 DP - 1975 Sep IS - 0514-7166 TA - Zentralbl Veterinarmed [B] PG - 544-55 CY - GERMANY, WEST IP - 7 VI - 22 JC - Y72 EM - 7604 PMID- 1199531 CU - 88 TT - Leptospirosis de los animales domesticos en el sur de Chile. Estudio serologico EA - A SO - Zentralbl Veterinarmed [B] 1975 Sep;22(7):544-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 76025447 AU - Sulzer CR AU - Glosser JW AU - Rogers F AU - Jones WL AU - Frix M TI - Evaluation of an indirect hemagglutination test for the diagnosis of human leptospirosis. LA - Eng MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - Antibody Specificity MH - Comparative Study MH - Diagnosis, Differential MH - Evaluation Studies MH - Hemagglutination Tests/*methods MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 760102 DP - 1975 Sep TA - J Clin Microbiol PG - 218-21 SB - M CY - UNITED STATES IP - 3 VI - 2 JC - HSH AA - Author EM - 7602 AB - A presumptive hemagglutination test for the serological diagnosis of leptospirosis in humans is described. The antigen was prepared from a soluble alcohol extract of an andamana strain sorbed to human O- negative erythrocytes and preserved by pyruvic aldehyde fixation. In this study, the overall sensitivity of the hemagglutination test was 92% in contrast to 69% for the presumptive slide agglutination test. The specificity was 95% for the hemagglutination test in comparison with 83% for the slide test. PMID- 1176629 CU - 89 SO - J Clin Microbiol 1975 Sep;2(3):218-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 75214682 AU - Johnson WD Jr AU - Silva IC AU - Rocha H TI - Serum creatine phosphokinase in leptospirosis. LA - Eng MH - Acute Disease MH - Alanine Aminotransferase/blood MH - Aspartate Aminotransferase/blood MH - Creatine Kinase/*blood MH - Diagnosis, Differential MH - *Enzyme Tests MH - Hepatitis A/diagnosis MH - Human MH - Leptospirosis/*diagnosis/enzymology MH - Muscles/enzymology MH - Spectrophotometry MH - Time Factors PT - JOURNAL ARTICLE DA - 751021 DP - 1975 Sep 1 IS - 0098-7484 TA - JAMA PG - 981-2 SB - A SB - M CY - UNITED STATES IP - 9 VI - 233 JC - KFR AA - Author EM - 7512 AB - Serum creatine phosphokinase (CPK) and serum glutamic oxaloacetic and pyruvic transaminase (SGOT, SGPT) levels were determined in 61 patients with leptospirosis and 16 with viral hepatitis during the acute phase of illness. The CPK value was elevated in 29 leptospirosis patients and normal in all 16 hepatitis patients. Conversely, mean SGOT and SGPT levels were lower in leptospirosis patients. The CPK determination is a simple test that may provide diagnostic information in a jaundiced patient, particularly when characteristic manifestations of leptospirosis are absent. The pattern of greatly elevated CPK levels with only modest elevations in transaminase values in an acutely jaundiced patient should strongly suggest a diagnosis of leptospirosis. PMID- 1173921 CU - 90 SO - JAMA 1975 Sep 1;233(9):981-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 76025521 AU - Turner LH TI - Proceedings: Leptospirosis. LA - Eng MH - Animal MH - Cattle MH - Dogs MH - *Leptospirosis/complications/diagnosis MH - Mice MH - Rats MH - Swine PT - JOURNAL ARTICLE DA - 751212 DP - 1975 Sep IS - 0021-9746 TA - J Clin Pathol PG - 755 SB - A SB - M CY - ENGLAND IP - 9 VI - 28 JC - HT3 EM - 7602 PMID- 1165304 SO - J Clin Pathol 1975 Sep;28(9):755 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 76017073 AU - Harrington R Jr TI - Leptospiral antibodies in serum from cattle, swine, horses, deer, sheep, and goats: 1973 and 1974. LA - Eng MH - Animal MH - *Antibodies, Bacterial MH - Artiodactyla/*immunology MH - Cattle/immunology MH - Deer/immunology MH - Goats/immunology MH - Horses/*immunology MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Sheep/immunology MH - Swine/immunology PT - JOURNAL ARTICLE DA - 751204 DP - 1975 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1367-70 SB - M CY - UNITED STATES IP - 9 VI - 36 JC - 40C AA - Author EM - 7601 AB - During 2 years (fiscal years 1973 and 1974), microscopic agglutination tests were performed on 12,565 serums from cattle, swine, horses, deer, sheep, and goats for the detection of leptospiral antibodies. The most frequent presumptive infecting serogroups were Hebdomadis, Pomona, Autumnalis, Ballum, Australis, and Canicola. PMID- 1163878 SO - Am J Vet Res 1975 Sep;36(9):1367-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 76017072 AU - Santa Rosa CA AU - Sulzer CR AU - Giorgi W AU - da Silva AS AU - Yanaguita RM AU - Lobao AO TI - Leptospirosis in wildlife in Brazil: isolation of a new serotype in the pyrogenes group. LA - Eng MH - Animal MH - Brazil MH - Cross Reactions MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification MH - Leptospira interrogans/immunology/isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Mice MH - *Opossums MH - Rats MH - Rodent Diseases/*microbiology PT - JOURNAL ARTICLE DA - 751204 DP - 1975 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1363-5 SB - M CY - UNITED STATES IP - 9 VI - 36 JC - 40C AA - Author EM - 7601 AB - A new leptospiral serotype in the serogroup Pyrogenes is described. The strain was isolated from one gray "four-eyed" opossum (Philander opossum). It is proposed that the serotype be designated guaratuba, strain An-7705. The isolations of serotypes ballum from the South American field mouse (Akodon arviculoides), szwajizak and icterohaemorrhagiae from the North American opossum (Didelphis marsupialis), and grippotyphosa from many other wild animal species as well as domesticated animals are also described. PMID- 1163877 SO - Am J Vet Res 1975 Sep;36(9):1363-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 76018298 AU - Lee R AU - Cross JH AU - Irving GS AU - Lane C AU - Watten RH TI - Surveillance of some infectious diseases among aircrew personnel in Southeast Asia. LA - Eng MH - *Aerospace Medicine MH - Antibodies/analysis MH - Asia, Southeastern MH - Aspartate Aminotransferase/blood MH - Blood/microbiology MH - Communicable Diseases/*epidemiology MH - Endolimax/isolation & purification MH - Entamoeba/isolation & purification MH - Escherichia/isolation & purification MH - Feces/microbiology/parasitology MH - Female MH - Giardia/isolation & purification MH - Hookworm Infections/epidemiology MH - Human MH - Male MH - Parasites/isolation & purification MH - Plasmodium vivax/isolation & purification MH - Salmonella typhi/isolation & purification MH - Shigella/isolation & purification MH - Support, U.S. Gov't, Non-P.H.S. MH - United States/ethnology MH - Viruses/isolation & purification PT - JOURNAL ARTICLE DA - 751204 DP - 1975 Sep TA - Aviat Space Environ Med PG - 1152-4 SB - M CY - UNITED STATES IP - 9 VI - 46 JC - 9JA AA - Author EM - 7601 AB - A 2-year analysis of specimens among aircrew personnel in Southeast Asia is reported. Stool specimens were examined for intestinal parasites and enteric bacteria, blood smears for blood parasites, and sera tested for transaminases (SGOT) and antibodies to Entamoeba histolytica, Toxoplasma gondii, Chikungunya and Japanese encephalitis viruses, Rickettsia tsutsugamushi, Leptospira sp. and Pseudomonas pseudomallei. One to four specimens each were obtained from 537 adult males and 20 females. There were 56 subjects with intestinal parasites as follows: Giardia lamblia (3.8%), Endolimax nana (2.6%), Entamoeba histolytica (1.4%), Entamoeba hartmanni (0.9%), Entamoeba coli (0.7%), Trichiuris trichiura (1.7%), Ascaris lumbricoides (1.4%), hookworm (0.9%), and Clonorchis sinensis (1.2%). Two individuals had malaria, Plasmodium vivax (0.6%). Pathogenic enteric bacteria were isolated from seven stool specimens; Shigella groups B and D (0.9%), Salmonella paratyphi (0.3%), and Arizona group (0.9%). Significantly elevated SGOT levels were found in 0.9% and antibodies to Japanese encephalitis virus in 1.5%, to Rickettsia tsutsugamushi in 1.2%, to Pseudomonas pseudomallei in 0.3%, to Entamoeba histolytica in 0.9% and to Toxoplasma gondii in 10.1%. No antibodies were found to Chikungunya virus or Leptospira sp. PMID- 1100040 CU - 90 SO - Aviat Space Environ Med 1975 Sep;46(9):1152-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 76101325 AU - Brockie RE TI - Letter: Isolation of Leptospira hardjo from the opossum (Trichosurus vulpecula). LA - Eng MH - Animal MH - Leptospira/*isolation & purification MH - Leptospirosis/*veterinary MH - New Zealand MH - Opossums/*microbiology PT - JOURNAL ARTICLE DA - 760320 DP - 1975 Sep IS - 0048-0169 TA - N Z Vet J PG - 216 CY - NEW ZEALAND IP - 9 VI - 23 JC - OBZ EM - 7605 PMID- 1060979 CU - 88 SO - N Z Vet J 1975 Sep;23(9):216 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 76101324 AU - de Lisle GW AU - Almand KB AU - Julian AF AU - Wallace J TI - Letter: Leptospirosis in the opossum (Trichosurus vulpecula). LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases MH - Leptospirosis/*veterinary MH - New Zealand MH - *Opossums PT - JOURNAL ARTICLE DA - 760320 DP - 1975 Sep IS - 0048-0169 TA - N Z Vet J PG - 215-6 CY - NEW ZEALAND IP - 9 VI - 23 JC - OBZ EM - 7605 PMID- 1060978 CU - 88 SO - N Z Vet J 1975 Sep;23(9):215-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 76131494 AU - Kozlovskii EV AU - Sushkova NK TI - [Use of immunofluorescence in diagnosing leptospirosis] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/diagnosis MH - Chronic Disease MH - Fluorescent Antibody Technique/*methods MH - Leptospirosis/diagnosis/*veterinary PT - JOURNAL ARTICLE DA - 760427 DP - 1975 Sep IS - 0042-4846 TA - Veterinariia PG - 112-3 CY - USSR IP - 9 JC - XCC EM - 7606 PMID- 766376 CU - 90 TT - Primenenie immunofluorestsentsii pri diagnostike leptospiroza SO - Veterinariia 1975 Sep;(9):112-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 76084300 AU - Ageev AV TI - [Epidemiological characteristics of a natural leptospirosis focus in the basin of Lake Nero, Yaroslavl Province] LA - Rus MH - Acute Disease MH - Adult MH - Animal MH - *Disease Reservoirs/veterinary MH - Human MH - Leptospirosis/*epidemiology/immunology/physiopathology MH - Russia MH - Seasons PT - JOURNAL ARTICLE DA - 760209 DP - 1975 Sep IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 147-8 SB - M CY - USSR IP - 9 VI - 0 JC - Y9O EM - 7604 PMID- 128271 CU - 92 TT - Epidemiologicheskaia kharakteristika prirodnogo ochaga leptospirozav kotlovine ozera Nero Iaroslavskoi oblasti SO - Zh Mikrobiol Epidemiol Immunobiol 1975 Sep;0(9):147-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 76172183 AU - Sitprija V AU - Kashemsant U AU - Arthachinta S AU - Poshyachinda V TI - Pathogenesis of renal failure in tropical diseases. LA - Eng MH - Human MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications MH - Malaria/*complications PT - JOURNAL ARTICLE DA - 760706 DP - 1975 Aug TA - Nippon Jinzo Gakkai Shi PG - 707-9 CY - JAPAN IP - 8 VI - 17 JC - KMK EM - 7608 PMID- 1241408 CU - 89 SO - Nippon Jinzo Gakkai Shi 1975 Aug;17(8):707-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 76032001 AU - Sheridan JP TI - Dogs, cats and other pets. LA - Eng MH - Animal MH - *Animals, Domestic MH - Arachnida MH - Bites and Stings MH - Cat Diseases MH - Cat-Scratch Disease MH - *Cats MH - Dog Diseases MH - *Dogs MH - Echinococcosis MH - Ectoparasitic Infestations MH - Fleas MH - Guinea Pigs MH - Human MH - Larva Migrans MH - Leptospirosis MH - Ornithosis MH - Pasteurella Infections MH - Rabbits MH - Rabies MH - Scabies MH - Tinea MH - Toxocara MH - Toxoplasmosis MH - *Zoonoses/prevention & control PT - JOURNAL ARTICLE DA - 751230 DP - 1975 Aug IS - 0032-6518 TA - Practitioner PG - 172-7 SB - M CY - ENGLAND IP - 1286 VI - 215 JC - PHQ EM - 7602 PMID- 1178618 CU - 90 SO - Practitioner 1975 Aug;215(1286):172-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76034287 AU - Akkermans JP TI - [Fertility problems caused by infectious agents pigs in the Netherlands(author's transl)] LA - Dut MH - Abortion, Veterinary/*etiology MH - Animal MH - Brucellosis/complications/transmission/*veterinary MH - English Abstract MH - Female MH - Fetal Death/etiology/veterinary MH - Hog Cholera/complications MH - Infertility/etiology/*veterinary MH - Leptospirosis/complications/transmission/*veterinary MH - Male MH - Parvoviridae MH - Pregnancy MH - Pseudorabies/complications MH - Swine MH - Swine Diseases/*etiology MH - Swine Vesicular Disease/complications PT - JOURNAL ARTICLE DA - 751212 DP - 1975 Aug 1 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 809-20 SB - M CY - NETHERLANDS IP - 15 VI - 100 JC - VRY AA - Author EM - 7602 AB - The concept of fertility problems is defined in the introduction and their economic importance in pig breeding are pointed out. The infectious causes of the problem are reviewed. Infections with L. tarassovi and with Aujezky's virus regularly lead to practically endemic abortions; Brucella suis and swine-plague infections do so sporadically. The SMEDI syndrom is considered. The clinical symptoms, diagnosis, epizootiology, and the therapeutical and prophylactic measures of these infections are discussed. In the case of brucellosis, attention is paid to the differential diagnosis in the serological examination. The incidence of Yersinia enterocolitica among the Dutch pig population is high. This micro-organism has antigen components in common with brucellae. In Holland the significance of infectious agents as the causes of sterility is not considered to be high. PMID- 1172635 CU - 90 TT - Fertiliteitsstoringen bij het varken in Nederland door infectieuze agentia EA - A SO - Tijdschr Diergeneeskd 1975 Aug 1;100(15):809-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 76076369 AU - Ris DR TI - The failure of genus-specific serological tests to detect leptospirosis in cattle and rabbits. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Complement Fixation Tests MH - Leptospirosis/diagnosis/*veterinary MH - Rabbits MH - Species Specificity PT - JOURNAL ARTICLE DA - 760209 DP - 1975 Aug IS - 0048-0169 TA - N Z Vet J PG - 164-6 CY - NEW ZEALAND IP - 8 VI - 23 JC - OBZ EM - 7604 PMID- 1060000 CU - 88 SO - N Z Vet J 1975 Aug;23(8):164-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 75220377 AU - Little TW AU - Salt GF TI - Isolation of a leptospira of the Pomona serogroup from a field vole. LA - Eng MH - Animal MH - Guinea Pigs MH - Hamsters MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification MH - Microtinae/*microbiology MH - Rodentia/*microbiology PT - JOURNAL ARTICLE DA - 751106 DP - 1975 Jul 19 IS - 0042-4900 TA - Vet Rec PG - 56 SB - M CY - ENGLAND IP - 3 VI - 97 JC - XBS EM - 7512 PMID- 1098271 CU - 90 SO - Vet Rec 1975 Jul 19;97(3):56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 75200475 AU - McDiarmid A TI - Some disorders of wild deer in the United Kingdom. LA - Eng MH - Animal MH - Antlers/growth & development MH - Ataxia/veterinary MH - Brucellosis/veterinary MH - Corynebacterium Infections/veterinary MH - Cysticercosis/veterinary MH - *Deer MH - Dictyocaulus Infections/epidemiology MH - Echinococcosis/veterinary MH - Fascioliasis/veterinary MH - Foot-and-Mouth Disease/epidemiology MH - Great Britain MH - Leptospirosis/veterinary MH - Lung Diseases, Parasitic/veterinary MH - Myiasis/veterinary MH - Neoplasms/veterinary MH - Pediculosis/veterinary MH - Staphylococcal Infections/veterinary MH - Tick Infestations/veterinary MH - Trichostrongylosis/veterinary MH - Tuberculosis/veterinary MH - Wounds and Injuries/veterinary MH - Wounds, Gunshot/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 750929 DP - 1975 Jul 5 IS - 0042-4900 TA - Vet Rec PG - 6-9 SB - M CY - ENGLAND IP - 1 VI - 97 JC - XBS EM - 7511 RF - 19 PMID- 124987 CU - 92 SO - Vet Rec 1975 Jul 5;97(1):6-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 76163608 AU - Tissot D AU - Mailloux M AU - Corroller YL TI - [Serological study on bovine leptospirosis in Guadeloupe (author's transl)] LA - Fre MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Disease Vectors MH - English Abstract MH - Leptospira/isolation & purification MH - Leptospirosis/epidemiology/immunology/*veterinary MH - West Indies PT - JOURNAL ARTICLE DA - 760706 DP - 1975 Jul-Aug IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 420-5 SB - M CY - FRANCE IP - 4 VI - 68 JC - C4G AA - Author EM - 7608 AB - A serological study on bovines in Guadeloupe (French Carraibes) was conducted during 1973-1974. 456 animals were tested. Their sera were examined by microscopic agglutination technique with 20 antigens. Antibodies against the following serogroups: Ballum, Icterohaemorrhagiae, Bataviae, Australis, Pomona and Sejroe, were found. Ballum is the first serogroup by frequency and titers of antibodies. One young animal was ill and Immunological Test revealed a high titer of antibodies against serogroup Sejroe. This work demonstrates the existence of animal leptospiroses in Guadeloupe. PMID- 1243757 CU - 88 TT - Enquete serologique sur les leptospiroses bovines en guadeloupe EA - A SO - Bull Soc Pathol Exot Filiales 1975 Jul-Aug;68(4):420-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 76163601 AU - Aubry P AU - Bordahandy R AU - Ferah T AU - Mailloux M AU - Thomas J TI - [An anademy of ictero-hemorrhagic leptospirosis in a military group in Algeria (author's transl] LA - Fre MH - Adult MH - Algeria MH - Antibodies, Bacterial MH - English Abstract MH - Human MH - Leptospira/isolation & purification MH - Male MH - Military Medicine MH - Weil's Disease/*epidemiology/immunology PT - JOURNAL ARTICLE DA - 760706 DP - 1975 Jul-Aug IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 370-6 SB - M CY - FRANCE IP - 4 VI - 68 JC - C4G AA - Author EM - 7608 AB - Seven cases of L.I.H. are noted simultaneously in a military group in the suburbs of Algier. It is an anademic by contamination at the same point, without interhuman infection. Only two of these cases have clinical symptoms to permit diagnosis of the others by research of specific antibodies (Immunodiagnosis). Anicteric forms are very frequent. This explains probably failure of diagnosis when epidemiological conditions are realized. This unawareness of leptospiroses is unfortunately a general phenomenon in the world. PMID- 1243751 CU - 88 TT - Une anademie de leptospirose ictero-hemorragique dans une collectivite militaire a Alger EA - A SO - Bull Soc Pathol Exot Filiales 1975 Jul-Aug;68(4):370-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76036390 AU - Fuchs GH AU - Burger G TI - [The result-sequence method (sequence analysis) in leptospira research. 3. Communication: The bilateral sequential test (de Boer, Armitage) for testing the difference of mean values of two binomial distributions (author's transl)] LA - Ger MH - Cyclophosphamide/*pharmacology MH - Drug Evaluation MH - English Abstract MH - Leptospira/drug effects/*metabolism MH - Mathematics MH - *Models, Biological MH - Oxygen Consumption/*drug effects PT - JOURNAL ARTICLE DA - 751223 DP - 1975 Jul IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 341-54 SB - M CY - GERMANY, WEST IP - 2-3 VI - 232 JC - Y52 AA - Author EM - 7602 AB - The influence of the liver-activated and non-activated cytostatic drug Cyclophosphamid on the respiration of Leptospira biflexa semaranga Veldrat S 173 was tested in three different concentrations by group- sequential testing of two relative frequencies in a two-sided test- reading. The conditioned probability theta = 0.82 results from thetan = 0.40 and thetaa = 0.75. On account of a practicable sample size, we choose theta' = 0.80 (activated form superior) and theta'' = 0.20 (non- activated form superior). The test-adjusted level of significance is alpha = 0.05 less than beta = 0.10. The expected values for the number of discordant pairs are Etheta' = Etheta'' = 13, Etheta = 1/1 = 14 and Ethetamax = 16. The acceptance inspection performed by control chart and tabulated reference figures results - in comparison with conventional procedures - in savings of discordant pairs of 65 per cent (concentration 10(-4) g/ml) in a decision in favour of activated form, of 65 per cent (concentration 10(-8) g/ml) in an equal efficiency of both states of Cyclophosphamid and of 10 per cent (concentration 10(- 11) g/ml) in a non-significant difference. Taking into consideration all unrestrictedly selected pairs, the duration of the experiment takes only 4.25 months instead of 6.75 if the statistical data analysis is not performed conventionally, but group-sequentially instead. PMID- 1179885 TT - Das Ergebnis-Folge-Verfahren (Sequenzanalyse) in der Leptospirenforschung. 3. Mitteilung: Der zweiseitig sequentielle Test (de Boer, Armitage) zum Prufen der Differenz von Mittelwerten zweier Binomialverteilungen EA - A SO - Zentralbl Bakteriol [Orig A] 1975 Jul;232(2-3):341-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 75207034 AU - Zeigler JA AU - VanEseltine WP TI - Isolation and chemical characterization of outer envelope of Leptospira pomona. LA - Eng MH - Amino Acids/analysis MH - Bacterial Proteins/analysis MH - Carbohydrates/analysis MH - Cell Fractionation MH - Cell Wall/analysis/ultrastructure MH - Centrifugation, Density Gradient MH - Chromatography, Gas MH - Chromatography, Thin Layer MH - Colorimetry MH - Fatty Acids/analysis MH - Hexosamines/analysis MH - Hexoses/analysis MH - Leptospira/*ultrastructure MH - Lipids/analysis MH - Microscopy, Electron MH - Pentoses/analysis MH - Phospholipids/analysis MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE DA - 751106 DP - 1975 Jul IS - 0008-4166 TA - Can J Microbiol PG - 1102-12 SB - M CY - CANADA IP - 7 VI - 21 JC - CJ3 AA - Author EM - 7512 AB - Cells of Leptospira interrogans serotype pomona harvested from a chemically defined medium were resuspended in 0.01 M phosphate buffer of pH 7.3. Electron microscopy showed that 90 min of exposure effectively ruptured the outer envelope, freeing it from the cells as small flakes. Both zonal centrifugation in sucrose gradients and centrifugation in isopycnic KBr and CsCl gradients could be used to separate the outer envelope from the axial filaments and protoplasmic cylinders. The latter method resulting in higher yields of purified envelope with the particular protocols used. Thin sections of isolated outer envelope showed the same trilaminar structure seen in sections of intact cells. The outer layers were 1.5 nm thick and appeared as single layers of electron-dense particles. The central electron- transparent layer was 2.0-2.5 nm thick and appeared structureless. The gross chemical composition of the purified outer envelope was 47% protein, 27% carbohydrate, and 23% lipid. Colorimetric carbohydrate determinations revealed hexose, pentose, and 6-deoxyhexose; hexosamine was identified during amino acid analysis. Muramic acid, heptose, and 2-keto-3-deoxyoctonate were not detected. Thin-layer chromatography revealed only polar lipids, about 98% phosphatidylethanolamine and 2% lysophosphatidylethanolamine. Fatty acids identified by gas-liquid chromatography were octadecanoic, octadecenoic, hexadecanoic, and hexadecenoic. Amino acid analysis revealed 17 amino acids, histidine and glutamic acid being most abundant. The outer envelope was interpreted to be comparable with the outer double-track layer found in the cell covering of gram-negative eubacteria. PMID- 1148944 SO - Can J Microbiol 1975 Jul;21(7):1102-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 75206948 AU - Saari M AU - Miettinen R AU - Alanko H TI - Uveitis: report of a 10-year survey in Northern Finland. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Bacterial Infections/complications MH - Child MH - Child, Preschool MH - Female MH - Finland MH - Human MH - Infant MH - Leptospirosis/complications MH - Leukemia, Lymphocytic/complications MH - Male MH - Middle Age MH - Rheumatic Diseases/complications MH - Sarcoidosis/complications MH - Time Factors MH - Toxoplasmosis, Ocular/complications MH - Tuberculosis, Ocular/complications MH - Uveitis/*epidemiology/etiology MH - Virus Diseases/complications PT - JOURNAL ARTICLE DA - 751108 DP - 1975 Jul IS - 0008-4182 TA - Can J Ophthalmol PG - 356-60 SB - M CY - CANADA IP - 3 VI - 10 JC - CJJ AA - Author EM - 7512 AB - In order to determine the distribution of etiologic and diagnostic categories of uveitis at the Oulu University Eye Hospital, 653 patients with uveitis treated during the years 1964-1974 were reviewed. Of the 653 patients, 321 were men and 332 women; 547 had anterior, 64 posterior and 42 generalzied uveitis; 524 unilateral and 129 bilateral; 570 acute and 83 chronic; and 446 single and 207 recurrent. The etiologic factors were distributed into rheumatoid (7.2%), streptococcal (4.1%), tuberculosis (3.7%), toxoplasmosis (3.3%), varicella-zoster (1.7%), sarcoidosis (1.4%), staphylococcal (1.1%), leptospirosis (0.6%), lymphatic leucemia (0.5%), herpes simplex (0.5%), yersinosis (0.1%) and undetermined cases (75.8%). There were no cases of syphilis. Most of the cases in this series were anterior and acute uveitis occurring mainly in the age group 20-59 years. PMID- 1080070 CU - 90 SO - Can J Ophthalmol 1975 Jul;10(3):356-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76030676 AU - Ris DR TI - Letter: Serological evidence for infection of sheep with Leptospira interrogans serotype hardjo. LA - Eng MH - Animal MH - Leptospira interrogans MH - New Zealand MH - Sheep MH - Sheep Diseases/*epidemiology MH - Weil's Disease/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 751218 DP - 1975 Jul IS - 0048-0169 TA - N Z Vet J PG - 154 CY - NEW ZEALAND IP - 7 VI - 23 JC - OBZ EM - 7602 PMID- 1058382 CU - 88 SO - N Z Vet J 1975 Jul;23(7):154 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 75200363 AU - Hunter R TI - Leptospira hardjo infection in a dairy herd. LA - Eng MH - Animal MH - Cattle MH - *Cattle Diseases MH - Female MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 751010 DP - 1975 Jul IS - 0042-4889 TA - Vet Med Small Anim Clin PG - 794 CY - UNITED STATES IP - 7 VI - 70 JC - XBO EM - 7511 PMID- 1041086 CU - 87 SO - Vet Med Small Anim Clin 1975 Jul;70(7):794 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 76047156 AU - Osada F AU - Kogure M AU - Kobayashi S TI - [Distribution of antibodies to Leptospira among the residence of Tokyo and its suburbs] LA - Jpn MH - Adult MH - Antibodies, Bacterial/*analysis MH - English Abstract MH - Eye Diseases/immunology MH - Female MH - Human MH - Leptospira/*immunology MH - Leptospirosis/immunology MH - Male MH - Tokyo PT - JOURNAL ARTICLE DA - 760126 DP - 1975 Jul IS - 0387-5911 TA - Kansenshogaku Zasshi PG - 288-95 CY - JAPAN IP - 7 VI - 49 JC - IJR EM - 7603 PMID- 810526 CU - 91 EA - A SO - Kansenshogaku Zasshi 1975 Jul;49(7):288-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [84 medline neighbors] UI - 75175241 AU - Kaiser GE AU - Doetsch RN TI - Letter: Enhanced translational motion of Leptospira in viscous environments. LA - Eng MH - Cell Movement MH - Leptospira interrogans/*physiology MH - Viscosity PT - JOURNAL ARTICLE DA - 750822 DP - 1975 Jun 19 IS - 0028-0836 TA - Nature PG - 656-7 SB - M CY - ENGLAND IP - 5510 VI - 255 JC - NSC EM - 7510 PMID- 1134561 SO - Nature 1975 Jun 19;255(5510):656-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 76094167 AU - Mailloux M TI - Leptospiroses equals zoonoses. LA - Eng MH - Animal MH - Carnivora MH - Carrier State/veterinary MH - Cattle MH - Cattle Diseases MH - Disease Reservoirs/veterinary MH - Dog Diseases MH - Dogs MH - Guinea Pigs MH - Hamsters MH - Human MH - Leptospira/cytology MH - *Leptospirosis/epidemiology/transmission/veterinary MH - Mice MH - Rats MH - Rodent Diseases MH - Swine MH - Swine Diseases MH - Water Microbiology MH - *Zoonoses PT - JOURNAL ARTICLE DA - 760324 DP - 1975 Jun TA - Int J Zoonoses PG - 45-54 SB - M CY - TAIWAN IP - 1 VI - 2 JC - GTK EM - 7605 PMID- 1205672 CU - 89 SO - Int J Zoonoses 1975 Jun;2(1):45-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 76094165 AU - Ryu E TI - An investigation of canine antileptospiral antibodies in Japan. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Dogs/*immunology MH - Female MH - Japan MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Male PT - JOURNAL ARTICLE DA - 760324 DP - 1975 Jun TA - Int J Zoonoses PG - 16-34 SB - M CY - TAIWAN IP - 1 VI - 2 JC - GTK AA - Author EM - 7605 AB - From 1970 through 1973, blood samples of 7113 attended dogs and 1615 stray dogs in 50 cities of Japan were examined for leptospiral antibodies by RMAT on filter paper specimens. Results were as follows: 1. Prevalences of antibodies against L. icterohaemorrhagiae and L. canicola in attended dogs in 50 cities ranged from 22.5% to 0% with an average of 9.8%. Those of stray dogs in 8 cities ranged from 52.5% to 0% with an average of 21.7%. 2. 64 and 37 of 7113 attended dog sera reached positively only against either L. icterohaemorrhagiae and L. canicola, respectively. 595 of 7113 attended dog sera reacted positively against both antigens. 3. In 820 attended dog sera tested against 8 leptospiral serotypes, 57 had antibodies against L. icterohaemorrhagiae, 52 against L. canicola, 2 against L. australis A, 10 against L. pyrogenes and 2 against L. grippotyphosa. 4. The prevalence of antibodies was twice as much in male dogs as in females. The prevalence in a healthy group was only half that of a sick group. Attended dogs below 4 years old had a higher antibody prevalence than any other age. The prevalence of antibodies in summer was lower than for any other season. PMID- 1205671 CU - 89 SO - Int J Zoonoses 1975 Jun;2(1):16-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 76094163 AU - Correa MO TI - Human leptospirosis in Brazil. LA - Eng MH - Brazil MH - Human MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology/immunology PT - JOURNAL ARTICLE DA - 760324 DP - 1975 Jun TA - Int J Zoonoses PG - 1-9 SB - M CY - TAIWAN IP - 1 VI - 2 JC - GTK AA - Author EM - 7605 AB - Serological data on the prevalence of human leptospiroses in certain regions of Brazil are presented. Out of 467 diseased and clinically healthy persons, 40 were positive in the Amazonia. The most frequent serotypes were grippotyphosa (27.5%), panama (25%), icterohaemorrhagiae (10%) and woffi (10%). In 1966 and 1970, 279 cases were identified in Recife (northeastern Brazil) during outbreaks subsequent to floods. Among these 92.5% belonged to the icterohaemorrhagiae serotype. From 1947 to 1972, in Sao Paulo City (southeastern Brazil), of 18,233 patients with clinical signs of leptospirosis, 2,237 were positive with 86.5% belonging to icterohaemorrhagiae. In all Brazil, 32 strains of leptospires were isolated, 27 of which belonged to the icterohaemorrhagiae serotype and one strain for each wolffi, canicola, grippotyphosa, andamana and alexi serotypes. PMID- 1205669 CU - 89 SO - Int J Zoonoses 1975 Jun;2(1):1-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76039262 AU - Campbell RS AU - Stallman ND TI - Letter: Importation of etorphine. LA - Eng MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/*microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/*veterinary MH - Male MH - Nephritis, Interstitial/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 751212 DP - 1975 Jun IS - 0005-0423 TA - Aust Vet J PG - 328 SB - M CY - AUSTRALIA IP - 6 VI - 51 JC - 9IE EM - 7602 PMID- 1167143 SO - Aust Vet J 1975 Jun;51(6):328 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 76007854 AU - Reasoner DJ TI - Microbiology-detection of bacterial pathogens and their occurrence. LA - Eng MH - Animal MH - Birds MH - Cattle MH - Drug Resistance, Microbial MH - Enterobacteriaceae Infections/microbiology MH - Gastrointestinal Diseases/microbiology MH - Human MH - Leptospirosis/microbiology MH - *Microbiology MH - Poultry MH - Salmonella Infections/microbiology MH - Sewage MH - Swine MH - Turtles MH - Water Microbiology PT - JOURNAL ARTICLE DA - 751204 DP - 1975 Jun IS - 0043-1303 TA - J Water Pollut Control Fed PG - 1581-7 CY - UNITED STATES IP - 6 VI - 47 JC - KDZ EM - 7601 PMID- 1159932 SO - J Water Pollut Control Fed 1975 Jun;47(6):1581-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 75171073 AU - Geistfeld JG TI - Leptospirosis in the United States, 1971-1973. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Cattle MH - Child MH - Disease Outbreaks MH - Disease Reservoirs MH - Disease Vectors MH - Dogs MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Rodentia MH - Serotyping MH - Swine MH - United States PT - JOURNAL ARTICLE DA - 750829 DP - 1975 Jun IS - 0022-1899 TA - J Infect Dis PG - 743-5 SB - A SB - M CY - UNITED STATES IP - 6 VI - 131 JC - IH3 EM - 7510 PMID- 1133494 CU - 88 SO - J Infect Dis 1975 Jun;131(6):743-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 76007853 AU - Craun GF TI - Microbiology--waterborne outbreaks. LA - Eng MH - Cholera/microbiology MH - *Disease Outbreaks MH - Dracunculiasis/microbiology MH - Dysentery, Bacillary/microbiology MH - Food Poisoning/microbiology MH - Gastroenteritis/microbiology MH - Giardiasis/microbiology MH - Hepatitis/microbiology MH - Leptospirosis/microbiology MH - Meningoencephalitis/microbiology MH - Pseudomonas Infections/microbiology MH - Salmonella Infections/microbiology MH - Schistosomiasis/microbiology MH - Shellfish MH - Typhoid/microbiology MH - *Water Microbiology MH - Water Pollution, Chemical MH - Water Supply PT - JOURNAL ARTICLE PT - REVIEW DA - 751204 DP - 1975 Jun IS - 0043-1303 TA - J Water Pollut Control Fed PG - 1566-81 CY - UNITED STATES IP - 6 VI - 47 JC - KDZ EM - 7601 RF - 89 PMID- 125804 CU - 92 SO - J Water Pollut Control Fed 1975 Jun;47(6):1566-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 75188505 AU - Adachi Y AU - Yanagawa R TI - Possible role of protein(s) as antigenic determinant of the type- specific main antigen of Leptospira kremastos strain Kyoto. LA - Eng MH - *Antigens, Bacterial MH - Bacterial Proteins/immunology MH - Carbohydrates/analysis MH - Chromatography MH - Chromatography, Paper MH - Complement Fixation Tests MH - *Epitopes MH - Immune Sera MH - Leptospira/*immunology MH - Lipids/analysis MH - Pronase MH - Protein Hydrolysates MH - Trypsin PT - JOURNAL ARTICLE DA - 751010 DP - 1975 Jun IS - 0019-9567 TA - Infect Immun PG - 1325-31 SB - M CY - UNITED STATES IP - 6 VI - 11 JC - GO7 EM - 7511 PMID- 49300 CU - 95 SO - Infect Immun 1975 Jun;11(6):1325-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 75194072 AU - Humphery TJ TI - Acute renal failure due to leptospirosis with hyponatraemia. LA - Eng MH - Acute Disease MH - Adult MH - Case Report MH - Human MH - Hyponatremia/*complications MH - Kidney Failure, Acute/*etiology MH - Male MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 750929 DP - 1975 May 17 IS - 0025-729X TA - Med J Aust PG - 621-2 SB - M CY - AUSTRALIA IP - 20 VI - 1 JC - M26 AA - Author EM - 7511 AB - Severe forms of leptospirosis causing acute renal failure are uncommon in Australia. Reported here is one such case, with marked hyponatraemia, which was treated with peritoneal dialysis. Biopsy findings are presented. It is believed that the infection was acquired in suburban periodomestic surroundings. PMID- 1143160 SO - Med J Aust 1975 May 17;1(20):621-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 75194065 TI - Editorial: Leptospirosis. LA - Eng MH - Animal MH - Australia MH - Human MH - Hyponatremia/complications MH - Kidney Diseases/etiology MH - *Leptospirosis/complications/epidemiology MH - Rats PT - JOURNAL ARTICLE DA - 750929 DP - 1975 May 17 IS - 0025-729X TA - Med J Aust PG - 606-7 SB - M CY - AUSTRALIA IP - 20 VI - 1 JC - M26 EM - 7511 PMID- 1143154 CU - 88 NI - A SO - Med J Aust 1975 May 17;1(20):606-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 76107924 AU - Atanasov NA AU - Vasilevskaia MD TI - [Polymorphism of water-soluble and triton-X 100-extractable esterases and proteins from Leptospira] LA - Rus MH - Bacterial Proteins/*analysis/isolation & purification MH - Electrophoresis, Polyacrylamide Gel MH - English Abstract MH - Esterases/*analysis/isolation & purification MH - Leptospira/*analysis/enzymology MH - Molecular Weight MH - Polyethylene Glycols MH - *Polymorphism (Genetics) PT - JOURNAL ARTICLE DA - 760305 DP - 1975 May IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 73-7 SB - M CY - USSR IP - 5 JC - Y9O AA - Author EM - 7605 AB - Electrophoresis in gel from polyacrylamide was used to study the water- soluble intracellular esterases, triton-X 100-extracted and proteins of three saprophytic and three pathogenic strains of leptospirae belonging to different serological types. The results of investigation of a relative mobility of 27 fractions with an esterasic activity and the molecular weight of eight of them showed that their polymorphism was mainly consecuent of structural differences. In examination of proteins extracted from the cell residues with triton-X 100 there was also revealed an intertype polymorphism: by acrylamide electrophoresis with sodium dodecylsulphate they were divided into 3--10 fractions with a molecular weight of from 20000 to 200000. The results of these studies are discussed as a manifestation of biochemical individuality of leptospirae of individual serological types. PMID- 1210911 CU - 90 TT - Polimorfizm vodorastvorimykh i ekstragirovannykh tritonom-X 100 esteraz i proteinov iz leptospir EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1975 May;(5):73-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 75204019 AU - Myers DM TI - Efficacy of combined furazolidone and neomycin in the control of contamination in Leptospira cultures. LA - Eng MH - Drug Combinations MH - Furazolidone/administration & dosage/*pharmacology MH - Leptospira/*drug effects MH - Neomycin/administration & dosage/*pharmacology MH - Time Factors PT - JOURNAL ARTICLE DA - 751011 DP - 1975 May IS - 0066-4804 TA - Antimicrob Agents Chemother PG - 666-71 CY - UNITED STATES IP - 5 VI - 7 JC - 6HK EM - 7511 PMID- 1147596 CU - 90 SO - Antimicrob Agents Chemother 1975 May;7(5):666-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 75163882 AU - Ternberg JL AU - Keating JP TI - Acute acalculous cholecystitis. Complication of other illnesses in childhood. LA - Eng MH - Abdomen MH - Age Factors MH - Burns/complications MH - Child MH - Child, Preschool MH - Cholangiography MH - Cholecystitis/*etiology MH - Diarrhea/complications MH - Female MH - Fever MH - Gallbladder/surgery MH - Human MH - Infant MH - Leptospirosis/complications MH - Male MH - Pain MH - Postoperative Complications/radiography PT - JOURNAL ARTICLE DA - 750720 DP - 1975 May IS - 0004-0010 TA - Arch Surg PG - 543-7 SB - A SB - M CY - UNITED STATES IP - 5 VI - 110 JC - 8IA AA - Author EM - 7509 AB - Seventy-four cases of acalculous cholecystitis in infants and children (seven personal cases and 67 from the literature) were analyzed. In 45 cases the cholecystitis appeared as a complication of another illness. The primary illnesses in our patients were leptospirosis (four cases), diarrhea (two cases), and third-degree burns (one case). All seven children were critically ill. Abdominal pain and an abdominal mass were present in all. Fever was present in six of the seven patients, jaundice in four. Tube cholecystostomies were done in all cases. After recovery from their illness, the five surviving patients had normal bilary tracts when studied by cholangiography via the tube. Acute acalculous cholecystitis in infancey and childhood as a complication of injury or illness should be treated as an undrained abcess. PMID- 1130999 SO - Arch Surg 1975 May;110(5):543-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 75215883 AU - Bisby JA TI - Letter: Brucellosis eradication. LA - Eng MH - Agglutination Tests MH - Brucellosis/*diagnosis MH - Diagnosis, Differential MH - Human MH - Leptospirosis/diagnosis MH - Q Fever/diagnosis PT - JOURNAL ARTICLE DA - 751106 DP - 1975 Apr 26 IS - 0025-729X TA - Med J Aust PG - 545 SB - M CY - AUSTRALIA IP - 17 VI - 1 JC - M26 EM - 7512 PMID- 1152704 SO - Med J Aust 1975 Apr 26;1(17):545 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 75200417 AU - Clegg FG AU - Heath PJ TI - Subclinical L icterohaemorrhagiae infection in dogs associated with a case of human leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Bites and Stings/complications MH - *Dog Diseases/microbiology MH - Dogs MH - Human MH - Kidney/microbiology MH - *Leptospira interrogans/immunology/isolation & purification MH - Leptospirosis/etiology/microbiology/*veterinary MH - Middle Age MH - Rats MH - Rodent Diseases/microbiology PT - JOURNAL ARTICLE DA - 751010 DP - 1975 Apr 26 IS - 0042-4900 TA - Vet Rec PG - 385 SB - M CY - ENGLAND IP - 17 VI - 96 JC - XBS EM - 7511 PMID- 1146150 SO - Vet Rec 1975 Apr 26;96(17):385 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 76034312 AU - Hartman EG AU - Brummelman B AU - Dikken H TI - Leptospirae of serotype lora of the serogroup Australis isolated for the first time from swine in the Netherlands. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Bacteriological Techniques MH - Escherichia coli/isolation & purification MH - Female MH - Guinea Pigs MH - Kidney Cortex/microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Leukorrhea/microbiology MH - Male MH - Netherlands MH - Pregnancy MH - Serotyping MH - Streptococcus/isolation & purification MH - Swine MH - Swine Diseases/*microbiology MH - Urine/microbiology MH - Uterus/microbiology PT - JOURNAL ARTICLE DA - 751228 DP - 1975 Apr 15 IS - 0040-7453 TA - Tijdschr Diergeneeskd PG - 421-5 SB - M CY - NETHERLANDS IP - 8 VI - 100 JC - VRY AA - Author EM - 7602 AB - Leptospirosis in swine, caused by serotype lora (serogroup Australis) was detected both serologically and by culture. The most important symptoms consisted in abortion during the final month of gestation and the birth of dead or not viable piglets. PMID- 1101443 CU - 90 SO - Tijdschr Diergeneeskd 1975 Apr 15;100(8):421-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 75172844 AU - Imamura S AU - Matsui H AU - Ashizawa Y TI - [Further studies on indirect hemagglutination test in leptospirosis] LA - Jpn MH - Animal MH - Hemagglutination Tests/*methods MH - Human MH - Leptospirosis/*diagnosis MH - Sheep/immunology PT - JOURNAL ARTICLE DA - 750820 DP - 1975 Apr IS - 0021-5082 TA - Nippon Eiseigaku Zasshi PG - 220 CY - JAPAN IP - 1 VI - 30 JC - KKN EM - 7510 PMID- 1169548 CU - 85 SO - Nippon Eiseigaku Zasshi 1975 Apr;30(1):220 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 75210944 AU - Cinco M AU - Cociancich L TI - Sensitivity in vitro of leptospira to oxamicetin. LA - Eng MH - Antibiotics/*pharmacology MH - Culture Media MH - Leptospira/*drug effects MH - Microbial Sensitivity Tests PT - JOURNAL ARTICLE DA - 751108 DP - 1975 Apr IS - 0021-8820 TA - J Antibiot (Tokyo) PG - 325-7 SB - M CY - JAPAN IP - 4 VI - 28 JC - HCF AA - Author EM - 7512 AB - Oxamicetin was tested against 12 strains of parasitic leptospira each representing a different serotype and serogroup, and 8 saprophytic strains in liquid media. The results showed general susceptibility of parasitic leptospira being MIC's from 0.1 to 0.5 mug/ml. The MIC's against saprophytic strains were 10 similar to 40 mug/ml. PMID- 1150532 SO - J Antibiot (Tokyo) 1975 Apr;28(4):325-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 75192288 AU - Barrett MW AU - Chalmers GA TI - A serologic survey of pronghorns in Alberta and Saskatchewan, 1970-1972. LA - Eng MH - Alberta MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antibodies, Viral/*analysis MH - Artiodactyla/*immunology MH - Bluetongue Virus/immunology MH - Bovine Virus Diarrhea-Mucosal Disease/microbiology MH - Brucella abortus/immunology MH - Cattle MH - Chlamydia/immunology MH - Encephalitis Virus, Eastern Equine/immunology MH - Encephalitis Virus, Western Equine/immunology MH - Hantavirus/immunology MH - Herpesvirus 1, Bovine/immunology MH - Leptospira/immunology MH - Parainfluenza Virus 3, Human/immunology MH - Reoviridae/immunology MH - RNA Viruses/immunology MH - Saskatchewan PT - JOURNAL ARTICLE DA - 751010 DP - 1975 Apr IS - 0090-3558 TA - J Wildl Dis PG - 157-63 SB - M CY - UNITED STATES IP - 2 VI - 11 JC - KEM AA - Author EM - 7511 AB - To determine the exposure of free-ranging pronghorns (Antilocapra americana Ord) to selected pathogens, serum samples were obtained from 33 live-trapped animals from southwestern Saskatchewan in 1970, and from 26 and 51 animals from southeastern Alberta, in 1971 and 1972, respectively. Antibodies were found to the agents of parainfluenza 3, bovine virus diarrhea, eastern and western encephalomyelitis, infectious bovine rhinotracheitis and the chlamydial group. No serologic reactors were found to the agents of bluetongue, epizootic hemorrhagic disease, brucellosis, or leptospirosis (4 serotypes). PMID- 167203 CU - 96 SO - J Wildl Dis 1975 Apr;11(2):157-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 75198365 AU - Tsai C-C AU - Fresh JW TI - Leptospira canalzonae in man: A case report. LA - Eng MH - Adult MH - Animal MH - Antigens/diagnostic use MH - Blood Chemical Analysis MH - Case Report MH - Diagnosis, Differential MH - Hepatitis A/diagnosis MH - Human MH - Leptospira/drug effects/immunology/*isolation & purification MH - Leptospirosis/*diagnosis/drug therapy/immunology MH - Male MH - Support, U.S. Gov't, Non-P.H.S. MH - Tetracycline/therapeutic use MH - Vietnam MH - Zoonoses PT - JOURNAL ARTICLE DA - 750924 DP - 1975 Mar IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 133-5 SB - M CY - THAILAND IP - 1 VI - 6 JC - UVN EM - 7511 PMID- 1170644 CU - 85 SO - Southeast Asian J Trop Med Public Health 1975 Mar;6(1):133-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 75199518 AU - Mazzonelli J AU - de Mazzonelli GD AU - Mailloux M TI - [Studies on the antigens of leptospires (author's transl)] LA - Fre MH - Absorption MH - Agglutinins MH - Antigen-Antibody Reactions MH - Antigens, Bacterial/*analysis MH - Cross Reactions MH - English Abstract MH - Heat MH - Immune Sera MH - Leptospira/*immunology MH - Leptospira interrogans PT - JOURNAL ARTICLE DA - 750929 DP - 1975 Mar TA - Tropenmed Parasitol PG - 35-42 SB - M CY - GERMANY, WEST IP - 1 VI - 26 JC - WGM AA - Author EM - 7511 AB - The authors show the existence of a TR (thermoresistant) antigen capable to withstand heating at 100 degrees C for 30 minutes. This antigen is present in Patoc I, serogroup Semaranga. It absorbs the corresponding immune serum at rates exceeding 99%, and appears to be the only antigen playing a part in the absorption of agglutinins. The existence of a TR antigen was demonstrated in various pathogenic serotypes. This antigen withstands heating at 80 degrees C for 10 minutes. The TR antigen absorbs antibodies of immune sera of the corresponding strains; and, in cross agglutination reactions, antibodies of the other immune sera of the studied pathogenic leptospires. the TR antigen of serotypes icterohaemorrhagiae Wijnberg, australis Ballico and pyrogenes Salinem are not able to absorb agglutinins of sera anti-Patoc I, whereas TR/Hebdomadis and TR/Pomona absorb as much as 20%. tr/hond Utrecht IV and TR/Patoc I (by absorbing their immune sera in cross agglutination) act as homologous strains with an absorption rate of 99%. The capability of absorption of TR changes according to the composition of culture media. This antigen, heated at 80 degrees C for 10 minutes and obtained pyrogenes Salinem is used for macroscopic diagnosis in slide test procedure by mixing equal proportions of antigen and serum. A positive reaction is indicated by distinct agglutination clumps. PMID- 1145724 CU - 89 TT - Recherches sur les antigenes des leptospires EA - A SO - Tropenmed Parasitol 1975 Mar;26(1):35-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76019329 AU - Koch GG AU - Tolley HD TI - A generalized modified-chi2 analysis of categorical bacteria survival data from a complex dilution experiment. LA - Eng MH - *Bacteriological Techniques MH - Leptospira/*growth & development/physiology MH - Models, Biological MH - Statistics MH - Support, U.S. Gov't, P.H.S. PT - JOURNAL ARTICLE DA - 751211 DP - 1975 Mar IS - 0006-341X TA - Biometrics PG - 59-101 SB - M CY - UNITED STATES IP - 1 VI - 31 JC - A5O AA - Author EM - 7602 AB - A well-known method of estimation for the density of bacteria in a sample solution is the most probable number (MPN) procedure. This paper considers the change in density through time of bacteria populations which are undergoing extinction. The MPN with its estimated variance for a fixed time point is a basic module of these investigations and is treated as a general implicit function of the cell proportions in linear categorical data analysis. These quantities are then used to fit exponential decay models over time by weighted least squares. When such models are supported by the data, comparisons of decay rates between populations under possibly different experimental conditions can be undertaken. This methodology is illustrated with an example pertaining to the survival experience of Leptospira autumnalis. PMID- 1100132 CU - 90 SO - Biometrics 1975 Mar;31(1):59-101 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 75200259 AU - Vlasov AI AU - Lebedev IG AU - Streletskaia RA TI - [Method of examining the vestibular analyzer in certain infectious diseases] LA - Rus MH - Communicable Diseases/*physiopathology MH - Electronystagmography MH - English Abstract MH - Hemorrhagic Fevers, Viral/physiopathology MH - Human MH - Kidney Diseases/physiopathology MH - Leptospirosis/physiopathology MH - Meningoencephalitis/physiopathology MH - Neurologic Manifestations MH - Syndrome MH - Vestibular Function Tests/*methods MH - Vestibule/*physiopathology PT - JOURNAL ARTICLE DA - 750913 DP - 1975 Mar-Apr IS - 0042-4668 TA - Vestn Otorinolaringol PG - 39-42 CY - USSR IP - 2 JC - XAY EM - 7511 PMID- 1079983 CU - 90 TT - O metodike obsledovaniia vestibuliarnogo analizatora pri nekotorykh infektsionnykh zabolevaniiakh EA - A SO - Vestn Otorinolaringol 1975 Mar-Apr;(2):39-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 75186378 AU - Feigin RD AU - Anderson DC TI - Human leptospirosis. LA - Eng MH - Adolescence MH - Animal MH - Animals, Domestic/microbiology MH - Carnivora/microbiology MH - Carrier State MH - Cats MH - Child MH - Disease Reservoirs MH - Dogs MH - Female MH - Guinea Pigs MH - Human MH - Immunization/veterinary MH - *Leptospira canicola/isolation & purification/pathogenicity MH - *Leptospira interrogans/isolation & purification MH - *Leptospirosis/diagnosis/immunology/pathology/prevention & control/transmission/veterinary MH - Mice MH - Rabbits MH - Rats MH - Weil's Disease/complications/pathology PT - JOURNAL ARTICLE PT - REVIEW DA - 750924 DP - 1975 Mar IS - 0590-8191 TA - CRC Crit Rev Clin Lab Sci PG - 413-67 SB - M CY - UNITED STATES IP - 4 VI - 5 JC - DSZ AA - Author EM - 7511 AB - Human leptospirosis is a subject of increasing interest. Although this disease was frequently associated with individuals whose occupation or geographic location placed them in close proximity to wild animals or farm animals, recent cases have been particularly prevalent in young children and adolescents in urban and suburban America. Many of the recent cases have been acquired from household pets, particularly from dogs or hamsters. In particular, healthy dogs who have been immunized with leptospiral organisms, thereby creating a significant risk for their owners. This article will review the pathophysiology, clincal manifestations, laboratory diagnosis, treatment, and prevention of leptospirosis in the modern era, with particular emphasis on a more complete understanding of the epidemiology of this disorder. RF - 240 PMID- 237740 CU - 94 SO - CRC Crit Rev Clin Lab Sci 1975 Mar;5(4):413-67 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 75166509 AU - Plesko I AU - Hruzik J AU - Hlavata Z TI - [Occupational leptospiroses in laboratory workers (author's transl)] LA - Slo MH - Animal MH - Dogs MH - English Abstract MH - Human MH - Laboratories MH - Leptospira canicola/pathogenicity MH - Leptospirosis/*transmission MH - *Occupational Diseases MH - Rats PT - JOURNAL ARTICLE DA - 750905 DP - 1975 Mar IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 77-83 CY - CZECHOSLOVAKIA IP - 2 VI - 24 JC - CSH EM - 7510 PMID- 236837 CU - 94 TT - Profesionalne leptospirozy u laboratornych pracovnikov EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1975 Mar;24(2):77-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 75179136 AU - Myers DM AU - Jelambi F TI - Isolation and identification of leptospira hardjo from cattle in Argentina. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/isolation & purification MH - Antigen-Antibody Reactions MH - Antigens, Bacterial/isolation & purification MH - Argentina MH - Cattle MH - Cattle Diseases/*epidemiology MH - Culture Media MH - Epitopes MH - Leptospira/immunology/*isolation & purification MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Serotyping MH - Support, U.S. Gov't, Non-P.H.S. PT - JOURNAL ARTICLE DA - 750909 DP - 1975 Mar IS - 0041-3232 TA - Trop Geogr Med PG - 63-70 SB - M CY - NETHERLANDS IP - 1 VI - 27 JC - WGJ AA - Author EM - 7510 AB - A serological evaluation was done on the prevalence of bovine leptospirosis in Argentina. In 1,857 serum samples obtained from the major cattle raising areas of the country, 59.1 percent showed leptospiral agglutinins in the microscopic-agglutination test. The most frequent leptospiral antigens showing antibody reactions were the hebdomadis group serotypes, of which 45.8 per cent of the sera reacted to Leptospira hardjo with titres ranging from 1:100 to 1:25,600. Six Leptospira isolations were made from 161 bovine kidneys collected at local abattoirs. Their isolation and subsequent identification as serotype L. hardjo is described. This study reports on L. hardjo in cattle of Argentina for the first time and confirms the need for improved cultural methodology for its isolation. PMID- 49113 CU - 95 SO - Trop Geogr Med 1975 Mar;27(1):63-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 76129827 AU - Frottier J AU - Modai J TI - [Leukocytosis and polynucleosis in infectious disease] LA - Fre MH - Bacterial Infections/*blood MH - Cell Nucleus MH - Endocarditis, Bacterial/complications MH - English Abstract MH - Human MH - Leptospirosis/complications MH - Leukocytosis/*etiology MH - Meningitis, Listeria/complications MH - Meningitis, Meningococcal/complications MH - Neutrophils/*cytology MH - Septicemia/complications MH - Staphylococcal Infections/complications MH - Streptococcal Infections/complications MH - Urinary Tract Infections/complications PT - JOURNAL ARTICLE DA - 760423 DP - 1975 Feb 26 IS - 0037-1777 TA - Sem Hop PG - 659-6 SB - M CY - FRANCE IP - 10 VI - 51 JC - ULD AA - Author EM - 7606 AB - During bacterial infections, the intensity of the polymorphonuclear leukocytosis depends on the bacterium but also on the mechanism and extent of the infection. Polymorphonuclear leukocytosis is greater during pyogenic and anaerobic infections. It is due to deep suppuration, septicemia of thrombophlebitic origin, acute endocarditis, purulent meningitis and pneumonia. The increase in the number of polymorphonuclear cells is, on the other hand, less marked in sub-acute bacterial endocarditis. Apart from bacterial infections, a polymorphonuclear leukocytosis is common in inflammatory disease, such as tissue necrosis and several malignant diseases. It may also be due to drug allergy. PMID- 175454 CU - 93 TT - Leucocytose et polynucleose en pathologie infectieuse EA - A SO - Sem Hop 1975 Feb 26;51(10):659-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 75159543 AU - Bertrand A AU - Janbon F TI - [Meningitis caused by leptospirosis] LA - Fre MH - Human MH - Leptospira/immunology MH - Leptospirosis/*complications MH - Meningitis/cerebrospinal fluid/diagnosis/*etiology MH - Neurologic Manifestations MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE DA - 750808 DP - 1975 Feb 11 IS - 0035-2640 TA - Rev Prat PG - 663-4, 667-70 CY - FRANCE IP - 9 VI - 25 JC - T1D EM - 7509 PMID- 1129568 LI - F TT - La meningite des leptospiroses SO - Rev Prat 1975 Feb 11;25(9):663-4, 667-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 75083005 AU - Binder L AU - Szalka A AU - Kemenes F AU - Szeky A TI - [Human disease caused by Leptospira canicola in Budapest] LA - Hun MH - Adolescence MH - Adult MH - Animal MH - Dog Diseases/microbiology MH - Dogs MH - Human MH - Hungary MH - Leptospira canicola/*isolation & purification MH - Leptospirosis/*etiology/microbiology/veterinary MH - Male MH - Zoonoses PT - JOURNAL ARTICLE DA - 750423 DP - 1975 Feb 9 IS - 0030-6002 TA - Orv Hetil PG - 317-9 CY - HUNGARY IP - 6 VI - 116 JC - OL8 EM - 7505 PMID- 234186 CU - 94 TT - Leptospira canicola okozta emberi megbetegedesek Budapesten SO - Orv Hetil 1975 Feb 9;116(6):317-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 76008446 AU - Akama K AU - Otani S AU - Mori M AU - Arimitsu Y TI - Studies on the potency test of antiserum for Weils disease by the intracutaneous method. LA - Eng MH - Animal MH - Female MH - Guinea Pigs MH - Immune Sera/*standards MH - *Immunization, Passive MH - Injections, Intradermal MH - Injections, Intraperitoneal MH - Leptospira interrogans/immunology MH - Neutralization Tests MH - Weil's Disease/immunology/*therapy PT - JOURNAL ARTICLE DA - 751204 DP - 1975 Feb IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 1-9 SB - M CY - JAPAN IP - 1 VI - 28 JC - KLZ AA - Author EM - 7601 AB - A method for estimating the leptospiricidal activity of therapeutic antiserum for Weil's disease was improved by using the intracutaneous method in guinea pigs. The neutralization curves between the leptospiral suspensions for challenge and the antisera were shown to be linear over a wide range of the dosis of the pathogen. Although the reproducibility of the neutralization experiments was high, a significant divergence was observed among the slopes in various test samples. However, the trouble due to such a discrepancy in the slope may practically be reduced if such an antiserum preparation that has a regression coefficient close to the mean of those of various neutralization lines constructed by many different products is adopted as the reference. A practical method for the potency test was suggested. PMID- 1160195 SO - Jpn J Med Sci Biol 1975 Feb;28(1):1-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 75121938 AU - Thorsteinsson SB AU - Sharp P AU - Musher DM AU - Martin RR TI - Leptospirosis: an underdiagnosed cause of acute febrile illness. LA - Eng MH - Acute Disease MH - Adult MH - Fever/*etiology MH - Human MH - Leptospirosis/*complications/diagnosis MH - Male PT - JOURNAL ARTICLE DA - 750609 DP - 1975 Feb IS - 0038-4348 TA - South Med J PG - 217-9 SB - A SB - M CY - UNITED STATES IP - 2 VI - 68 JC - UVH AA - Author EM - 7507 AB - Two cases of leptospirosis diagnosed at the Texas Medical Center in a two-week period are presented. Most cases of leptospirosis go undiagnosed because the symptoms and signs are nonspecific. Leptospirosis should enter the differential diagnosis when symptoms of influenzal illness, aseptic meningitis, and viral gastroenteritis occur, especially if abnormal hepatic and renal function are shown to be present. Many, but by no means all, patients will give history of exposure to livestock or rodents. Diagnosis is best made by serologic methods; Treatment is usually not required since the disease is self- limited, and even in the more severe form, antibiotics have not been conclusively shown to be of benefit. PMID- 1118754 SO - South Med J 1975 Feb;68(2):217-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76008470 AU - Azuma I AU - Taniyama T AU - Yamamura Y AU - Yanagihara Y AU - Hattori Y TI - Chemical studies on the cell walls of Leptorspira biflexa strain Urawa and Treponema pallidum strain Reiter. LA - Eng MH - Amino Acids/analysis MH - Bacterial Proteins/analysis MH - Carbohydrates/analysis MH - Cell Wall/analysis MH - Leptospira/*analysis MH - Peptidoglycan/*analysis MH - Polysaccharides, Bacterial/*analysis MH - Treponema pallidum/*analysis PT - JOURNAL ARTICLE DA - 751204 DP - 1975 Feb IS - 0021-5139 TA - Jpn J Microbiol PG - 45-51 SB - M CY - JAPAN IP - 1 VI - 19 JC - KMF AA - Author EM - 7601 AB - The preparation and chemical properties of the cell walls of Leptospira biflexa Urawa and Treponema pallidum Reiter are described. Both cell walls are composed mainly of polysaccharides and peptidoglycans. The data of chemical analysis indicate that the cell wall of L. biflexa Urawa contains rhamnose, arabinose, xylose, mannose, galactose, glucose and unidentified sugars as neutral sugars, and alanine, glutamic acid, alpha, epsilon-diaminopimelic acid, glucosamine and muramic acid as major amino acids and amino sugars. As major chemical constituents of the cell wall of T. pallidum Reiter, rhamnose, arabinose, xylose, mannose, galactose, glucose, alanine, glutamic acid, ornithine, glycine, glucosamine and muramic acid have been detected. The chemical properties of protein and polysaccharide fractions prepared from the cells of T. pallidum Reiter were also partially examined. PMID- 1099288 CU - 90 SO - Jpn J Microbiol 1975 Feb;19(1):45-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 75117814 AU - Washington JA 2d TI - Blood cultures: principles and techniques. LA - Eng MH - Anti-Infective Agents/blood MH - Antisepsis MH - Bacteria/immunology MH - *Bacteriological Techniques MH - Blood/*microbiology MH - Blood Bactericidal Activity MH - Blood Specimen Collection MH - Blood Volume MH - Brucella/isolation & purification MH - Culture Media MH - Fungi/isolation & purification MH - Human MH - Infant, Newborn MH - Leptospira/isolation & purification MH - Septicemia/blood MH - Skin/microbiology MH - Time Factors PT - JOURNAL ARTICLE PT - REVIEW DA - 750602 DP - 1975 Feb IS - 0025-6196 TA - Mayo Clin Proc PG - 91-8 SB - M CY - UNITED STATES IP - 2 VI - 50 JC - LLY AA - Author EM - 7507 AB - Detecting the presence of microorganisms in blood is an important function of the clinical microbiology laboratory. With prompt isolation, identification, and antimicrobial susceptibility testing of bacterial isolates, the clinician can modify the selection and dosage of the antimicrobics used initially to treat a suspected septicemia. Principles and techniques for blood collection, culture, examination, and reporting are reviewed. RF - 78 PMID- 1090789 CU - 90 SO - Mayo Clin Proc 1975 Feb;50(2):91-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 75096126 AU - Jones PW AU - Matthews PR TI - Examination of slurry from cattle for pathogenic bacteria. LA - Eng MH - Animal MH - Brucella/*isolation & purification MH - Cattle MH - England MH - Feces/*microbiology MH - Fertilizers/analysis MH - Hamsters MH - Leptospira/*isolation & purification MH - Salmonella/classification/*isolation & purification MH - Salmonella Phages MH - Serotyping MH - Wales PT - JOURNAL ARTICLE DA - 750521 DP - 1975 Feb IS - 0022-1724 TA - J Hyg (Lond) PG - 57-64 SB - M CY - ENGLAND IP - 1 VI - 74 JC - IEF AA - Author EM - 7506 AB - One hundred and eighty-seven samples of slurry from cattle were examined forthe presence of salmonellas, pathogenic leptospires and brucellas. Small numbers of salmonellas, generally less than 1/g., were isolated from 20 samples (11%). These were S. dublin (12), S. typhimurium (4), S. indiana (1), S. bredeney (1), S. cerro (1) and S. unnamed 4, 12:d:-(1). Leptospires were isolated from 56 samples (30%) but none was pathogenic for hamsters. No brucellas were isolated. The results of this survey are discussed in relation to the epidemiology of salmonellosis. PMID- 1054059 CU - 88 SO - J Hyg (Lond) 1975 Feb;74(1):57-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 75192126 AU - Moch RW AU - Ebner EE AU - Barsoum LS AU - Botros BA TI - Leptospirosis in Ethiopia: a serological survey in domestic and wild animals. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals/microbiology MH - Animals, Domestic/*microbiology MH - Antibodies, Bacterial/*analysis MH - Birds MH - Camels MH - Cattle MH - Dogs MH - Ethiopia MH - Goats MH - Haplorhini MH - Horses MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Rats MH - Serotyping MH - Sheep MH - Swine PT - JOURNAL ARTICLE DA - 751011 DP - 1975 Feb IS - 0022-5304 TA - J Trop Med Hyg PG - 38-42 SB - M CY - ENGLAND IP - 2 VI - 78 JC - KAV AA - Author EM - 7511 AB - Seven hundred and fifty-eight serum samples from domestic and wild animals in Ethiopia were tested for leptospiral antibodies by the microscopic agglutination test. The following percentages of seropositivity were obtained: horse (91.3 per cent), cow (70.7 per cent), pig (57.1 per cent), goat (47.3 per cent), sheep (43.4 per cent), camel (15.4 per cent), and dog (8.3 per cent). All 54 samples from birds and wild animals were seronegative. Most of the positive sera exhibited reaction to more than one serotype and antibodies to serotype butembo were predominant in sera of the majority of the examined species. However, grippotyphosa, rather than butembo was the predominant reacting serotype in camels and dogs. It is concluded that leptospirosis is of significant prevalence in domestic animals in Ethiopia and may constitute an occupational health hazard to man. PMID- 806698 CU - 91 SO - J Trop Med Hyg 1975 Feb;78(2):38-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 75096708 AU - Lindenbaum I AU - Eylan E AU - Raanani E TI - Enhancement of growth of Leptospira icterohaemorrhagiae by tissue cell cultures. LA - Eng MH - Animal MH - Cell Count MH - Cell Line MH - Chick Embryo MH - Clone Cells MH - Comparative Study MH - Culture Media MH - Fibroblasts MH - Growth Substances MH - Hamsters MH - Haplorhini MH - Hemoglobins MH - Human MH - Kidney MH - Leptospira interrogans/*growth & development/pathogenicity MH - *Tissue Culture MH - Virulence PT - JOURNAL ARTICLE DA - 750517 DP - 1975 Feb IS - 0022-1287 TA - J Gen Microbiol PG - 358-62 SB - M CY - ENGLAND IP - 2 VI - 86 JC - I87 EM - 7506 PMID- 803551 CU - 91 SO - J Gen Microbiol 1975 Feb;86(2):358-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 77220943 AU - Hagiwara MK AU - Rosa CA TI - [Canine leptospirosis in the state of Sao Paulo (author's transl)] LA - Por MH - Animal MH - Brazil MH - Comparative Study MH - Dog Diseases/*epidemiology MH - Dogs MH - English Abstract MH - Hepatic Encephalopathy/epidemiology/veterinary MH - Kidney Failure, Acute/epidemiology/veterinary MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 770825 DP - 1975 IS - 0020-3653 TA - Arq Inst Biol (Sao Paulo) PG - 111-8 SB - M CY - BRAZIL VI - 42 JC - 8VF AA - Author EM - 7710 AB - In this paper the occurrence of leptospirosis was studied by the search of agglutininis antileptospira, in 10 dogs with symptoms of the disease. Another group of 22 animals with hepatic or renal insufficiency was also studied for the correlation between both insufficiency and leptospirosis. Finally, a third group of 40 dogs, clinically normal, was also included in this study. In 60% of suspected cases the clinical diagnosis was confirmed by the presence of specific agglutinins to serotypes icterohaemorrhagiae, canicola, grippotyphosa and bataviae. Among animals with renal or hepatic insufficiency it was found 36.3% of reagents while in the normal group the rate was only 7.5%. The serotype butembo was detected serologically in dogs for the first time in Brazil. PMID- 1242081 CU - 88 TT - Leptospirose canina em Sao Paulo. EA - A SO - Arq Inst Biol (Sao Paulo) 1975;42:111-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 77109692 AU - De Azevedo JF AU - Rombert P AU - Palmeiro JM TI - [Minor survey on trichinosis and leptospirosis in swine] LA - Por MH - Animal MH - Comparative Study MH - English Abstract MH - Leptospirosis/epidemiology/*veterinary MH - Portugal MH - Rats MH - Swine MH - Swine Diseases/*epidemiology MH - Trichinosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 770321 DP - 1975 Jan-Dec IS - 0303-7762 TA - An Inst Hig Med Trop (Lisb) PG - 377-80 CY - PORTUGAL IP - 1-4 VI - 3 JC - 4DL EM - 7705 PMID- 1241974 CU - 88 TT - Pequeno rastreio sobre a triquinelose e a leptospirose em suinos EA - A SO - An Inst Hig Med Trop (Lisb) 1975 Jan-Dec;3(1-4):377-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 76123247 AU - Kida H AU - Ishii T AU - Watanabe H AU - Tsunehisa Y AU - Yamamoto S TI - [New Leptospira vaccine. I. Preparation of a vaccine using synthetic media] LA - Jpn MH - Animal MH - *Bacterial Vaccines MH - *Culture Media MH - Guinea Pigs MH - Leptospira interrogans/*immunology PT - JOURNAL ARTICLE DA - 760410 DP - 1975 Jan IS - 0021-4930 TA - Nippon Saikingaku Zasshi PG - 151 CY - JAPAN IP - 1 VI - 30 JC - KHZ EM - 7606 PMID- 1240206 CU - 85 SO - Nippon Saikingaku Zasshi 1975 Jan;30(1):151 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 76123246 AU - Takashima I AU - Yamagawa R TI - [Protective effect of somatic components of Leptospira] LA - Jpn MH - Animal MH - Antigens, Bacterial MH - Cell Wall/immunology MH - Guinea Pigs MH - Leptospira interrogans/*immunology MH - Weil's Disease/*immunology PT - JOURNAL ARTICLE DA - 760410 DP - 1975 Jan IS - 0021-4930 TA - Nippon Saikingaku Zasshi PG - 150 CY - JAPAN IP - 1 VI - 30 JC - KHZ EM - 7606 PMID- 1240205 CU - 85 SO - Nippon Saikingaku Zasshi 1975 Jan;30(1):150 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 76025895 AU - Ezhov GI AU - Kiktenko VS AU - Berezov TT TI - Nucleic acid content and nucleotide composition of DNA in leptospirae. LA - Eng MH - Chromatography, Paper MH - Cytosine/analysis MH - DNA, Bacterial/*analysis MH - Guanine/analysis MH - Leptospira/*analysis/classification/pathogenicity MH - Nucleotides/*analysis MH - RNA, Bacterial/*analysis MH - Spectrophotometry PT - JOURNAL ARTICLE DA - 760102 DP - 1975 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 246-53 SB - M CY - CZECHOSLOVAKIA IP - 2 VI - 19 JC - IEV AA - Author EM - 7602 AB - The contents of DNA and RNA were studied in 9 strains of leptospirae and the composition of nitrogen bases of DNA in 20 strains of pathogenic and saprophytic leptospirae. It has been found that leptospirae contain a high per cent ration of nucleic acids. According to the nucleotide composition, the family of Leptospira as a whole belongs to the AT-type. According to overall guanine and cytosine contents, the investigated strains of pathogenic leptospirae fall into 3 groups and differ from the seprophytic strains. With respect to the limited number of the investigated strains, the DNA nucleotide composition of leptospirae can be used as a supplementary biochemical criterion in the classification of leptospirae. PMID- 1236884 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1975;19(2):246-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76230499 AU - Canazi F AU - Crupi D AU - Quartarone F TI - [Research of beta-galactosidase in the leptospira] LA - Ita MH - English Abstract MH - Galactosidases/*metabolism MH - Human MH - Italy MH - Leptospira/classification/*enzymology MH - Leptospirosis/*enzymology MH - Serotyping PT - JOURNAL ARTICLE DA - 760823 DP - 1975 Jan-Feb IS - 0003-472X TA - Ann Sclavo PG - 50-4 CY - ITALY IP - 1 VI - 17 JC - 65C AA - Author EM - 7610 AB - The Authors have investigated on the presence of beta-galactoxidase in the serotypes of Leptospires most frequently employed for the diagnosis of the formes epidemiologic occurrent in Italy. With the two employed methodes it was possible to make evident the enzyme in all the serotypes, but not in L. saxkoebing (Mus 24); L. ballum (Castellon 3), L. doberdo (Percedol 3). PMID- 1230036 TT - Sulla ricerca della beta-galattosidase nelle leptospire EA - A SO - Ann Sclavo 1975 Jan-Feb;17(1):50-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 76202166 AU - Csata S AU - Gallyas F AU - Szendi L AU - Koller O TI - Acute renal failure caused by leptospirosis. LA - Eng MH - Adult MH - Anuria/etiology MH - Case Report MH - Hemodialysis MH - Human MH - Hungary MH - Kidney Failure, Acute/*etiology/physiopathology/therapy MH - Leptospirosis/*complications/physiopathology MH - Male MH - Military Personnel PT - JOURNAL ARTICLE DA - 760802 DP - 1975 IS - 0001-5431 TA - Acta Chir Acad Sci Hung PG - 175-81 SB - M CY - HUNGARY IP - 2 VI - 16 JC - 0GM AA - Author EM - 7609 AB - Three patients with severe leptospirosis leading to anuria and treated with haemodialysis are reported. One patient died. The pathomechanism and the underlying pathological and histological changes of the renal failure are discussed. It is stressed that the clinical diagnosis of leptospirosis is often difficult, as other infectious diseases,first of all infectious hepatitis, frequently present the same symptoms. PMID- 1227224 SO - Acta Chir Acad Sci Hung 1975;16(2):175-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76156909 AU - Kazarian AS TI - [Serological indicators of microagglutination and lysis in rabbits immunized simultaneously against leptospirosis, pasteurellosis ans brucellosis] LA - Rus MH - Agglutinins/isolation & purification MH - Animal MH - Antibody Formation MH - Bacterial Vaccines/*administration & dosage MH - Brucellosis/*prevention & control MH - Hemagglutination Tests MH - Hemolysis MH - Leptospirosis/*prevention & control MH - Pasteurella Infections/*prevention & control MH - Rabbits PT - JOURNAL ARTICLE DA - 760510 DP - 1975 IS - 0044-4510 TA - Zh Eksp Klin Med PG - 37-42 CY - USSR IP - 3 VI - 15 JC - Y9J EM - 7607 PMID- 1220472 TT - Serologicheskie pokazateli po mikroaggliutinatsii i lizisu u krolikov, immunizirovannykh odnovremenno protiv leptospiroza, pasterelleza i brutselleza SO - Zh Eksp Klin Med 1975;15(3):37-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 76131542 AU - Stoichev S AU - Todorova R TI - [Attempts at obtaining a pentavalent vaccine against leptospirosis] LA - Bul MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Formation/drug effects MH - *Bacterial Vaccines/pharmacology MH - English Abstract MH - Immunization MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology MH - Rabbits MH - Time Factors PT - JOURNAL ARTICLE DA - 760427 DP - 1975 IS - 0506-8215 TA - Vet Med Nauki PG - 34-8 SB - M CY - BULGARIA IP - 4 VI - 12 JC - XCE AA - Author EM - 7606 AB - Obtained was a five-valent vaccine (Leptospira pomona, L. canicola, L. grippotyphosa, L. mitis, and L. icterohaemorrhagiae). It was found that storage at 4degreesC does not impair the immunogenicity of the vaccine in the course of one year. Three groups of rabbits were used to test its immunogenicity--group I, injected once, subcutaneously, with 1 cu. cm of the vaccine; group II, injected subcutaneously, twice, at an interval of 7 days, with 1 cu. cm of the vaccine each time; and group III, injected once, muscularly, with 1 cu. cm. The animals were kept under observation for twelve months. It was established that in the case of intramuscular treatment there were highest antibody titers in the blood serum persisting up to the twelfth month. PMID- 1216680 CU - 90 TT - Opiti za poluchavane na petvalentna vaksina protiv leptospiroza EA - A SO - Vet Med Nauki 1975;12(4):34-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 76115374 AU - Myers DM AU - Jones CJ TI - Leptospira fort-bragg isolated from a rat in Barbados. LA - Eng MH - Animal MH - Barbados MH - Cattle MH - Cattle Diseases/etiology MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/etiology/veterinary MH - Rats/*microbiology MH - Serotyping PT - JOURNAL ARTICLE DA - 760415 DP - 1975 TA - Bull Pan Am Health Organ PG - 208-11 CY - UNITED STATES IP - 3 VI - 9 JC - BSB AA - Author EM - 7606 AB - Leptospira fort-bragg was isolated from the kidney tissue of a rat (Rattus rattus) trapped on a plantation in St. Philip Parish, Barbados. This constitutes the first reported isolation of this Autumnalis group serotype outside of the United States and its first known isolation from an animal species. Serologic evidence is presented which indicates that this serotype may be the cause of leptospiral infections in Barbadian cattle. PMID- 1212536 CU - 89 SO - Bull Pan Am Health Organ 1975;9(3):208-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 76111412 AU - Nicolescu M AU - Borsai L AU - Ionescu-Dorohoi T TI - Serotype identification of Romanian leptospira strains belonging to the Pomona serogroup. LA - Eng MH - Leptospira/*classification/isolation & purification MH - Serotyping/methods PT - JOURNAL ARTICLE DA - 760324 DP - 1975 Jan-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 47-54 CY - ROMANIA IP - 1-2 VI - 34 JC - 8EM EM - 7605 PMID- 1212075 SO - Arch Roum Pathol Exp Microbiol 1975 Jan-Jun;34(1-2):47-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 76111411 AU - Nicolescu M AU - Moldoveanu G TI - Serotype determination of reference strains in the Pomona serogroup. Results obtained by using antisera prepared with living and respectively heat-killed leptospira as antigens. LA - Eng MH - Antigens, Bacterial/analysis MH - Cross Reactions MH - Leptospira/*classification/immunology MH - Serotyping/methods PT - JOURNAL ARTICLE DA - 760324 DP - 1975 Jan-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 41-6 CY - ROMANIA IP - 1-2 VI - 34 JC - 8EM EM - 7605 PMID- 1212074 SO - Arch Roum Pathol Exp Microbiol 1975 Jan-Jun;34(1-2):41-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 76105285 AU - Weber A AU - Karuss H TI - [Current zoonoses in veterinary practice. 2. Bacterial infections] LA - Ger MH - Animal MH - Bacterial Infections/*veterinary MH - Brucellosis/epidemiology MH - Brucellosis, Bovine/epidemiology MH - Cattle MH - Germany, West MH - Human MH - Leptospirosis/epidemiology MH - Pasteurella Infections/epidemiology MH - Salmonella Infections/epidemiology MH - Salmonella Infections, Animal/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 760320 DP - 1975 IS - 0303-6286 TA - Tierarztl Prax PG - 271-6 SB - M CY - GERMANY, WEST IP - 3 VI - 3 JC - VS4 EM - 7605 RO - M:BDS PMID- 1209594 LR - 850301 CU - 88 TT - Aktuelle Zoonosen in der tierarztlichen Praxis. 2. Erkrankungen durch Bakterien SO - Tierarztl Prax 1975;3(3):271-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 76103690 AU - Cacchione RA AU - Cascelli ES AU - Martinez ES TI - [Serologic survey on human leptospirosis in Argentina] LA - Spa MH - Adolescence MH - Adult MH - Aged MH - Argentina MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Infant MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Socioeconomic Factors PT - JOURNAL ARTICLE DA - 760324 DP - 1975 Jan-Apr TA - Rev Asoc Argent Microbiol PG - 21-7 SB - M CY - ARGENTINA IP - 1 VI - 7 JC - RCB AA - Author EM - 7605 AB - This paper presents the results obtained with the sera of persons having direct or indirect contact with ethiological agents of leptospirosis. Exposure could have ocurred during the performance of their duties, by contact with contaminated habitats and/or animals. One thousand thirty eight sera from persons living in different regions of Argentina were received at the laboratory and studied by the microscopic agglutination tecnique. Of these, 164 were positive (15.7%) to serveral serotypes. One hundred thirty eight sera of the 857 males studied (16.1%) were positive, and 16 out of 173 female sera (15%) were positive. Males between 31 and 40 years of age had the highest proportion of positives (21.7%); however, among females the group between 21 and 30 years of age had the highest rate (14.2%). Most of the sera reacted to L. brastislava (15%), followed by L. icterohaemorrhagiae (17.7%) and L. butembo (14%), with nine other serotypes at lower rates. PMID- 1208897 CU - 89 TT - Encuesta serologica sobre leptospirosis humana en Argentina EA - A SO - Rev Asoc Argent Microbiol 1975 Jan-Apr;7(1):21-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76084229 AU - Kazarian AS TI - [Preventive properties of blood sera of rabbits immunized with 3 vaccines by separate, complex and combined application] LA - Rus MH - Animal MH - Bacterial Vaccines/*pharmacology MH - *Blood Bactericidal Activity MH - Brucella Vaccine/administration & dosage MH - Brucellosis/immunology MH - Leptospirosis/immunology MH - Pasteurella Infections/immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 760227 DP - 1975 IS - 0044-4510 TA - Zh Eksp Klin Med PG - 32-9 CY - USSR IP - 4 VI - 15 JC - Y9J EM - 7604 PMID- 1199562 TT - Preventivnye svoistva syvorotok krovi krolikov, immunizirovannykh tremia vaktsinami razdel'no, kompleksno i assotsiirovanno SO - Zh Eksp Klin Med 1975;15(4):32-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 76056279 AU - Tuncel E AU - Ogutman R TI - [The incidence of leptospirosis around Erzurum] LA - Tur MH - Adolescence MH - Adult MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Infant MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Turkey PT - JOURNAL ARTICLE DA - 760110 DP - 1975 IS - 0049-4844 TA - Turk Hij Tecr Biyol Derg PG - 101-21 CY - TURKEY IP - 3 VI - 34 JC - WKI EM - 7603 PMID- 1189041 CU - 88 TT - Erzurum ve cevresinde leptospirozis insidansi uzerinde calismalar EA - A SO - Turk Hij Tecr Biyol Derg 1975;34(3):101-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 76037373 AU - Liven E TI - Deoxyribonuclease production by leptospires. LA - Eng MH - Culture Media MH - Deoxyribonucleases/*metabolism MH - Leptospira/*enzymology MH - Leptospira canicola/*enzymology PT - JOURNAL ARTICLE DA - 751228 DP - 1975 IS - 0044-605X TA - Acta Vet Scand PG - 477-9 CY - DENMARK IP - 3 VI - 16 JC - 27V EM - 7602 PMID- 1180199 SO - Acta Vet Scand 1975;16(3):477-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76036347 AU - Mateew D AU - Manew C TI - [The etiology structure of the leptospiroses in Bulgaria (author's transl)] LA - Ger MH - Animal MH - Bulgaria MH - English Abstract MH - Human MH - Leptospira/*classification MH - Leptospira canicola/classification MH - Leptospira interrogans/classification MH - Leptospirosis/*microbiology/veterinary MH - Serotyping PT - JOURNAL ARTICLE DA - 751223 DP - 1975 Jan IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 67-80 SB - M CY - GERMANY, WEST IP - 1 VI - 230 JC - Y52 AA - Author EM - 7602 AB - In the course of many years the authors have studied the etiological structure of the leptospiroses in Bulgaria and have typed a significant number of leptospira strains isolated from humans and animals. The strains have been isolated by the authors themselves for the most part, while some others have been received from other laboratories in the country. The contributions of other authors in this field have been taken into consideration. In identifying these strains use has been made of the methods of the cross agglutination-lysis reaction and the cross absorption according to Schuffner and Bohlander, while in typing the strains from the Icterohaemorrhagiae and Australis serogroups there have been applied also factor sera according to the method of KMETY. The presence of the following serotypes has been established in Bulgaria: L. icterohaemorrhagiae, L. copenhageni, L. sofia, L. canicola, L. bulgarica, L. srebarna, L. lora, L. jalna, L. bratislava, L. pomona, L. mozdok, L. tsaratsovo, L. sejroe, L. balcanica, L. saxkoebing, L. mini, L. batabiae, L. tarassovi. Three of these serotypes, namely, L. sofia (874) L. bulgarica (Nikolaevo) and L. balcanica (1627 Burgas), have been isolated for the first time in Bulgaria, accepted as independent serotypes, and included as such in the International Classification Scheme of the Leptospirae. The serotypes srebarna and tsaratsovo have recently been established by MANEV as independent Bulgarian serotypes, but they have not yet been accepted internationally as such, since no control has been carried out by other reference laboratories. PMID- 1179869 TT - Atiologische Struktur der Leptospirosen in Bulgarien EA - A SO - Zentralbl Bakteriol [Orig A] 1975 Jan;230(1):67-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 75221235 AU - Cinco M AU - Nityananda K TI - Classification of 8 new strains of Leptospira isolated in Ceylon. LA - Eng MH - Agglutination Tests MH - Animal MH - Dogs MH - Human MH - Leptospira/*classification/immunology MH - Rats MH - Serotyping MH - Sri Lanka MH - Swine/microbiology PT - JOURNAL ARTICLE DA - 751107 DP - 1975 IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 365-8 SB - M CY - GERMANY, WEST IP - 1-3 VI - 231 JC - Y52 EM - 7512 PMID- 1154913 SO - Zentralbl Bakteriol [Orig A] 1975;231(1-3):365-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 75221216 AU - Takashima I AU - Yanagawa R TI - Failure of transformation in leptospira with two genetic markers of streptomycin resistance and the ability to grow in a synthetic medium. LA - Eng MH - Culture Media MH - *Drug Resistance, Microbial MH - DNA, Bacterial/metabolism MH - Genetics, Microbial MH - *Leptospira/drug effects/growth & development MH - Leptospira interrogans MH - Mutation MH - Streptomycin/*pharmacology MH - Temperature MH - *Transformation, Genetic PT - JOURNAL ARTICLE DA - 751107 DP - 1975 IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 180-6 SB - M CY - GERMANY, WEST IP - 1-3 VI - 231 JC - Y52 AA - Author EM - 7512 AB - Transformability of Leptospira was investigated with the two genetic markers, streptomycin (SM) resistance and the ability to grow in SHENBERG's synthetic medium. DNA was extracted from the two mutants of L. icterohaemorrhagiae strain Shibaura, which were SM-resistant and able to grow in SHENBERG's medium. Recipients were 5 strains of L. icterohaemorrhagiae and 1 strain of L. copenhageni. Studies taking careful consideration of the growth phase of the recipient cells, transformation medium, and incubation temperature did not produce the appearance of transformant. Transformation of L. kremastos with SM resistance also showed a negative result. PMID- 1154904 SO - Zentralbl Bakteriol [Orig A] 1975;231(1-3):180-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 75221215 AU - Chernukha YG AU - Kokovin IL AU - Ananyina YV AU - Ryabov NI AU - Devyatova AP TI - Dependence of pathogenic properties of leptospires on animal subspecies. LA - Eng MH - Animal MH - Antibody Formation MH - Carrier State MH - Hamsters MH - Leptospira/immunology/*pathogenicity MH - Mice/*microbiology MH - Serotyping MH - Species Specificity PT - JOURNAL ARTICLE DA - 751107 DP - 1975 IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 175-9 SB - M CY - GERMANY, WEST IP - 1-3 VI - 231 JC - Y52 AA - Author EM - 7512 AB - 1. Leptospires of mozdok serotype of the Pomona serogroup possessed specific pathogenic properties for a definite subspecies of Apodemus agrarius. They caused carriership in rodents of a European population, but were unable to cause such a process in Far East mice. However, leptospires of monjakov and pomona types were also unable to provoke leptospiruria in these small mammals. 2. The intensity of the formation of antibody to leptospires in different subspecies of Apodemus agrarius was dependent on the degree of their susceptibility, determined by the presence of renal leptospirosis. Leptospira-carriers among animals reacted by antibody formation 6-40 times more intensive than in those not susceptible to the infection. 3. Leptospires of pomona, monjakov and mozdok serotypes of the Pomona group taxonomically can be designated as separate subspecies, on the basis of differences in biological properties as related to their natural animal reservoirs. PMID- 1154903 SO - Zentralbl Bakteriol [Orig A] 1975;231(1-3):175-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 75180599 AU - Kazarian AS TI - [Allergic indices in relation to brucellosis in rabbits immunized with brucellosis vaccine separately as well as in a complex and in association with leptospirosis and pasteurellosis vaccines] LA - Rus MH - Animal MH - Bacterial Vaccines/*administration & dosage MH - Brucella Vaccine/*administration & dosage MH - Brucellosis/*immunology MH - Chronic Disease MH - Drug Therapy, Combination MH - Fever/immunology MH - *Immunization MH - Leptospirosis/immunology MH - Pasteurella Infections/immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 750829 DP - 1975 IS - 0044-4510 TA - Zh Eksp Klin Med PG - 35-9 CY - USSR IP - 1 VI - 15 JC - Y9J EM - 7510 PMID- 1136622 TT - Allergicheskie pokazateli v otnoshenii brutselleza u krolikov, immunizirovannykh brutselleznoi vaktsinoi razdel'no, a takzhe kompleksno i assotsiirovanno s leptospiroznoi i pasterelleznoi vaktsinami SO - Zh Eksp Klin Med 1975;15(1):35-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75145098 AU - Petrov EM AU - Chernukha IG TI - [Sensitivity of certain strains of pathogenic Leptospira to streptomycin, the nature of resistant variants and the frequency of their occurrence] LA - Rus MH - Animal MH - Cattle MH - Clone Cells/microbiology MH - Culture Media MH - Dose-Response Relationship, Drug MH - *Drug Resistance, Microbial MH - English Abstract MH - Gene Frequency/*drug effects MH - Human MH - Leptospira/*drug effects MH - Microbial Sensitivity Tests MH - Mutation/drug effects MH - Rodentia/microbiology MH - Serotyping MH - Streptomycin/*pharmacology MH - Swine/microbiology MH - Time Factors MH - Variation (Genetics)/*drug effects PT - JOURNAL ARTICLE DA - 750625 DP - 1975 Jan IS - 0003-5637 TA - Antibiotiki PG - 62-6 SB - M CY - USSR IP - 1 VI - 20 JC - 6GC AA - Author EM - 7508 AB - Streptomycin sensitivity of 112 Leptospira strains isolated from domestic and wild animals was studied. Independent of the isolation period and nature the strains proved to be highly sensitive to the antiobiotic (MIC 0.1 to 0.5 gamma/ml). On the example of a clone strain of Leptospira it was shown with a fluctuation test that streptomycin resistance occurred spontaneously. Frequency of the streptomycin resistant mutations was determined for 5 clone strains of L. interrogans. It was 10-9 to 10-7 per a Leptospira. PMID- 1122127 CU - 90 TT - Chuvstvitel'nost' nekotorykh shtammov patogennykh leptospir k streptomitsinu, priroda ustoichivykh k nemu variantov i chastota ikh vozniknoveniia EA - A SO - Antibiotiki 1975 Jan;20(1):62-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 75107331 AU - Huhn RG AU - Hanson LE AU - Killinger AH AU - Cardella MA TI - Immunity to leptospirosis: Leptospira interrogans serotype pomona bacterins in cattle. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibody Formation MH - *Bacterial Vaccines/administration & dosage MH - Cattle MH - Cattle Diseases/*immunology MH - Female MH - Hamsters MH - Immunization, Passive MH - Injections, Subcutaneous MH - Kidney Diseases/immunology/veterinary MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Male MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 750504 DP - 1975 Jan IS - 0002-9645 TA - Am J Vet Res PG - 59-65 SB - M CY - UNITED STATES IP - 1 VI - 36 JC - 40C AA - Author EM - 7506 AB - Immunity to renal leptospirosis was demonstrated in cattle vaccinated with Leptospira interrogans serotype pomona. Vaccinated cattle, challenge inoculated with virulent L interrogans serotype pomona organisms 12 months after vaccination, were resistant to renal infection; similarly inoculated, but nonvaccinated, cattle were susceptible to renal infection. Relationship was demonstrated between immunity induced in vaccinated cattle and that induced in hamsters vaccinated with a dilution of the same bacterin and later inoculated with virulent L interrogans serotype pomona organisms. PMID- 1115419 SO - Am J Vet Res 1975 Jan;36(1):59-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 75104094 AU - Malakhov IuS AU - Solov'eva VS AU - Shupliko AN AU - Gushchin VN AU - Seregin IG TI - [Vaccination of cattle against leptospirosis] LA - Rus MH - Agglutination Tests/veterinary MH - Animal MH - Cattle MH - Cattle Diseases/*immunology MH - Immune Sera/immunology MH - Immunity MH - Leptospirosis/immunology/*veterinary MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 750510 DP - 1975 Jan IS - 0042-4846 TA - Veterinariia PG - 43-5 CY - USSR IP - 1 JC - XCC EM - 7506 PMID- 1114667 TT - Vaktsinatsiia krupnogo rogatogo skota protiv leptospiroza SO - Veterinariia 1975 Jan;(1):43-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [107 medline neighbors] UI - 75079423 AU - Alexander AD AU - Evans LB AU - Baker MF AU - Baker HJ AU - Ellison D AU - Marriapan M TI - Pathogenic leptospiras isolated from Malaysian surface waters. LA - Eng MH - Agglutination Tests MH - Cross Reactions MH - Fresh Water MH - Leptospira/*classification/isolation & purification/pathogenicity MH - Malaysia MH - Serotyping MH - Soil Microbiology MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 750419 DP - 1975 Jan IS - 0003-6919 TA - Appl Microbiol PG - 30-3 SB - M CY - UNITED STATES IP - 1 VI - 29 JC - 6K0 AA - Author EM - 7505 AB - Pathogenic leptospiras (1,424) isolated from natural waters and wet soils in Malaysia comprised 29 different serovars (synonym serotypes). All except two of the serovars had been found previously in Malaysia. The exceptional serovars were werrasingha, an Autumnalis serogroup member originally isolated in Ceylon, and a new serovar designated evansi. Serovar evansi had serological affinities with serovar ranarum which was isolated from the kidney of a frog in Iowa. The large variety of serovars found in jungle areas was consistent with similar previous findings of diverse serovar infections in troops who had operated in Malaysian jungles. PMID- 1110490 LR - 750925 CU - 90 SO - Appl Microbiol 1975 Jan;29(1):30-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 76108820 AU - McDiarmid A TI - Some diseases of free-living wildlife. LA - Eng MH - Animal MH - Animal Diseases/*epidemiology MH - Artiodactyla MH - Ataxia/veterinary MH - Bird Diseases/epidemiology MH - Birds MH - Brucellosis/epidemiology/veterinary MH - Cattle MH - Cattle Diseases/epidemiology MH - Chiroptera MH - Deer MH - Dog Diseases/epidemiology MH - Dogs MH - Foot-and-Mouth Disease/epidemiology MH - Foxes MH - Hedgehogs MH - Lagomorpha MH - Leptospirosis/veterinary MH - Louping Ill/epidemiology MH - Microtinae MH - Newcastle Disease/epidemiology MH - Pasteurella Infections/veterinary MH - Pigeons MH - Rabies/veterinary MH - Reindeer MH - Salmonella Infections, Animal/epidemiology MH - Sheep MH - Skunks MH - Tuberculosis/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 760330 DP - 1975 IS - 0065-3519 TA - Adv Vet Sci Comp Med PG - 97-126 SB - M CY - UNITED STATES VI - 19 JC - 2PR EM - 7605 RF - 138 PMID- 1108621 CU - 90 SO - Adv Vet Sci Comp Med 1975;19:97-126 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 76108819 AU - Galuzo IG TI - Landscape epidemiology (epizootiology). LA - Eng MH - Animal MH - Animal Diseases/*transmission MH - Arthropod Vectors MH - Artiodactyla MH - Bird Diseases/transmission MH - Birds MH - Cattle MH - Cattle Diseases/transmission MH - Disease Vectors MH - Ecology MH - Foot-and-Mouth Disease/transmission MH - Geography MH - Goats MH - Helminthiasis/veterinary MH - Human MH - Insect Vectors MH - Leptospirosis/veterinary MH - Rodentia MH - Seasons MH - Sheep MH - Soil MH - Swine MH - Ticks MH - Toxoplasmosis, Animal/transmission PT - JOURNAL ARTICLE PT - REVIEW DA - 760330 DP - 1975 IS - 0065-3519 TA - Adv Vet Sci Comp Med PG - 73-96 SB - M CY - UNITED STATES VI - 19 JC - 2PR EM - 7605 RF - 58 PMID- 1108620 CU - 90 SO - Adv Vet Sci Comp Med 1975;19:73-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 76067177 AU - Litvin VY TI - Physical simulation in epizootology of non-transmissive zoonoses. LA - Eng MH - Animal MH - Carrier State/veterinary MH - Cobalt Radioisotopes MH - Disease Outbreaks/*veterinary MH - Dyes MH - Feces/microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/veterinary MH - Microtinae MH - *Models, Theoretical MH - Phosphorus Radioisotopes MH - Urine/microbiology MH - *Zoonoses PT - JOURNAL ARTICLE DA - 760209 DP - 1975 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 251-6 CY - CZECHOSLOVAKIA IP - 3 VI - 22 JC - F2T EM - 7604 PMID- 1104417 CU - 90 SO - Folia Parasitol (Praha) 1975;22(3):251-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 76060805 AU - Minzat RM AU - Tomescu V TI - [Detection of pathogenic leptospira in the waste water and sewage sludge of large pig breeding sites] LA - Ger MH - Animal MH - Bacteriological Techniques MH - Breeding MH - English Abstract MH - *Housing, Animal MH - Leptospira/*isolation & purification/pathogenicity MH - Sewage/*analysis MH - Soil Microbiology MH - *Swine MH - Waste Disposal, Fluid MH - Water Microbiology PT - JOURNAL ARTICLE DA - 760126 DP - 1975 IS - 0003-9055 TA - Arch Exp Veterinarmed PG - 557-62 SB - M CY - GERMANY, EAST IP - 4 VI - 29 JC - 70I AA - Author EM - 7603 AB - Sewage effluent and sludge from the purification plant of 8 large piggeries was examined for the presence of pathogenic leptospires. By using the methods of Appelman and Van Thiel it was found that 43.1% of samples of effluent were contaminated with L. pomona and O. tarassovi. Altogether 33 strains of pomona and three mixed cultures of pomona and tarassovi were obtained. The isolated strains were shown to be pathogenic by experimental infection of guinea-pigs, rabbits and pregnant and non-pregnant sows. The average period of survival of pathogenic leptospires in sewage effluent was 24 to 48 hours, with a maximum of 96 hours. Leptospires were killed within 24 hours in decanted sludge, owing to its strong acidity. PMID- 1103773 CU - 90 TT - Uber den Nachweis von pathogenen Leptospiren in den Abwassern und im Klarschlamm von Schweinegrossanlagen EA - A SO - Arch Exp Veterinarmed 1975;29(4):557-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 79180253 AU - Stoenner HG TI - Summary report on the 1975 survey for leptospirosis in the United States. LA - Eng MH - Agglutination Tests MH - Animal MH - *Animals, Domestic MH - Diagnosis, Differential MH - Leptospira/classification MH - Leptospirosis/diagnosis/*veterinary MH - United States PT - JOURNAL ARTICLE DA - 790725 DP - 1975 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 145-9 CY - UNITED STATES IP - 79 JC - PY5 EM - 7909 PMID- 1078045 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1975;(79):145-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 75222227 AU - Wiesmann E AU - Mosimann J AU - Drolshammer I AU - Eckert J AU - Marki H AU - Munzinger J AU - Schurter V AU - Schweizer H TI - [Study of Brazilian agricultural workers. A medico-socio-psychological study] LA - Ger MH - Adolescence MH - Adult MH - Agricultural Workers' Diseases/epidemiology MH - Amebiasis/epidemiology MH - Body Height MH - Body Weight MH - Brazil MH - Brucellosis/epidemiology MH - Chagas Disease/epidemiology MH - Child MH - Child, Preschool MH - Echinococcosis/epidemiology MH - English Abstract MH - Enzymes/blood MH - Female MH - Helminthiasis/epidemiology MH - Human MH - Infant MH - Leptospirosis/epidemiology MH - Male MH - Middle Age MH - Morbidity MH - Ornithosis/epidemiology MH - Parasitic Diseases/blood MH - Protozoan Infections/epidemiology MH - Rickettsia Infections/epidemiology MH - *Rural Health MH - Syphilis/epidemiology MH - Toxoplasmosis/epidemiology MH - Tuberculosis/epidemiology MH - Virus Diseases/epidemiology PT - JOURNAL ARTICLE DA - 751108 DP - 1975 IS - 0001-706X TA - Acta Trop PG - 1-36 SB - M CY - SWITZERLAND IP - 1 VI - 32 JC - 23A AA - Author EM - 7512 AB - The general state of health of native Brazilian agricultural workers - a total of 750 people from 3 different plantations in the States of Parana and Saso Paulo - was examined. The main interest of this study war centred on infectious and parasitic diseases, nutritional conditions as well as social, intellectual factors. Observations: Apart from the high number of cases of helminthiasis, amounting to 80%, the general state of health of the examined subjects was found to be good - indeed better than that of a hypothetical, comparable group of Europeans. Except for the Chagas' disease, by which 5% of the test subjects were afflicted, infectious diseases posed no serious problems. There was no case of malnutrition. The relatively lower intellectual level can not be attributed to any heriditary factor, and could definitely be improved by proper schooling. Corrective measures: Chagas: Since brick houses have replaced the wooden ones for several years, new infections are unlikely. Helminthiasis: In addition to the anthelminthic treatment, sanitary prophylactic measures should be taken. Social-intellectual factors: The following points should be emphasized: elementary schooling on the plantations; teaching at intermediary level; sewing and cooking courses; general hygience. PMID- 239549 CU - 94 TT - Untersuchung von Landarbeitern in Brasilien Eine medizinisch- sozialpsychologische Studie EA - A SO - Acta Trop 1975;32(1):1-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 75107333 AU - Huhn RG AU - Baldwin CD AU - Cardella MA TI - Immunity to leptospirosis: bacterins in dogs and hamsters. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Dog Diseases/*prevention & control MH - Dogs/*immunology MH - Hamsters/*immunology MH - Kidney Diseases/veterinary MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/*veterinary MH - Male MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 750504 DP - 1975 Jan IS - 0002-9645 TA - Am J Vet Res PG - 71-4 SB - M CY - UNITED STATES IP - 1 VI - 36 JC - 40C AA - Author EM - 7506 AB - Resistance to clinical and renal leptospirosis in dogs vaccinated with a bacterin containing Leptospira interrogans serotype canicola and Leptospira interrogans serotype icterohaemorrhagiae was demonstrated. The relationship between resistance induced in vaccinated dogs and that induced in vaccinated hamsters was also demonstrated, using criteria of leptospiremia, renal infection, leptospiruria, and clinical signs of disease in dogs and death in hamsters. PMID- 234704 CU - 94 SO - Am J Vet Res 1975 Jan;36(1):71-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 75107332 AU - Huhn RG AU - Kokjohn JL AU - Cardella MA TI - Immunity to leptospirosis: antiserums in dogs and hamsters. LA - Eng MH - Animal MH - Dog Diseases/pathology/*prevention & control MH - Dogs/*immunology MH - Hamsters/*immunology MH - *Immune Sera MH - *Immunization, Passive MH - Kidney/pathology MH - Kidney Diseases/prevention & control/veterinary MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/prevention & control/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 750504 DP - 1975 Jan IS - 0002-9645 TA - Am J Vet Res PG - 67-70 SB - M CY - UNITED STATES IP - 1 VI - 36 JC - 40C AA - Author EM - 7506 AB - Resistance to clinical and renal leptospirosis in dogs injected with antiserum to Leptospira interrogans serotype canicola and Leptospira interrogans serotype icterohaemorrhagiae was demonstrated. The relationship between resistance induced in serum-injected hamsters was also demonstrated, using criteria of leptospiremia, renal infection, leptospiruria, and clinical signs of disease in dogs and death in hamsters. PMID- 234703 CU - 94 SO - Am J Vet Res 1975 Jan;36(1):67-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 76123245 AU - Adachi Y AU - Yanagawa R TI - [Type-specific antigenic determinants of Leptospira. Possible participation of proteins] LA - Jpn MH - Bacterial Proteins/*immunology MH - *Epitopes MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 760410 DP - 1975 Jan IS - 0021-4930 TA - Nippon Saikingaku Zasshi PG - 149 CY - JAPAN IP - 1 VI - 30 JC - KHZ EM - 7606 PMID- 55506 CU - 95 SO - Nippon Saikingaku Zasshi 1975 Jan;30(1):149 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 79180252 AU - Ellinghausen HC Jr TI - Variable factors influencing the isolation of leptospires involving culture ingredients and testing. LA - Eng MH - Animal MH - *Bacteriological Techniques MH - Culture Media MH - Hydrogen-Ion Concentration MH - Leptospira interrogans/growth & development/*isolation & purification MH - Micropore Filters MH - Serum Albumin, Bovine PT - JOURNAL ARTICLE DA - 790725 DP - 1975 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 126-41 CY - UNITED STATES IP - 79 JC - PY5 EM - 7909 PMID- 35790 CU - 94 SO - Proc Annu Meet U S Anim Health Assoc 1975;(79):126-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 76115133 AU - Severina LO AU - Bashkatova NA TI - [The effect of bile acids and their salts on the lipolytic activity of microorganisms] LA - Rus MH - Alcaligenes/enzymology MH - Animal MH - Bacteria/*enzymology MH - Bile Acids and Salts/*pharmacology MH - Candida/enzymology MH - Catalysis MH - Chemistry MH - Digestion MH - Enzyme Activation MH - Fungi/*enzymology MH - Human MH - Hydrogen-Ion Concentration MH - Intestines/microbiology MH - Leptospira/enzymology MH - Lipase/*metabolism MH - Lipids/metabolism MH - Mucor/enzymology MH - Pancreas/enzymology MH - Pseudomonas/enzymology MH - Rhizopus/enzymology MH - Staphylococcus aureus/enzymology MH - Surface-Active Agents/pharmacology MH - Taurocholic Acid/pharmacology PT - JOURNAL ARTICLE PT - REVIEW DA - 760430 DP - 1975 TA - Biol Nauki PG - 91-9 SB - M CY - USSR IP - 9 JC - A3B EM - 7606 RF - 32 PMID- 2339 CU - 94 TT - Vliianie zhelchnykh kislot i ikh solei na lipoliticheskuiu aktivnost' mikroorganizmov SO - Biol Nauki 1975;(9):91-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 75183202 AU - Arthachinta S AU - Sitprija V AU - Kashemsant U TI - Selective renal angiography in renal failure due to infection. LA - Eng MH - Adult MH - Escherichia coli Infections/*complications MH - Female MH - Human MH - Kidney Failure, Acute/etiology/*radiography MH - Leptospirosis/*complications MH - Malaria/*complications MH - Male MH - Middle Age MH - Renal Artery/*radiography MH - Septicemia/*complications PT - JOURNAL ARTICLE DA - 750822 DP - 1974 Dec IS - 0004-8461 TA - Australas Radiol PG - 446-52 CY - AUSTRALIA IP - 4 VI - 18 JC - 9IU EM - 7510 PMID- 4618473 CU - 90 SO - Australas Radiol 1974 Dec;18(4):446-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 76030636 AU - Hodges RT TI - Bovine leptospirosis: the detection of haemolysin inhibitors in sera from experimentally and naturally infected cattle. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*immunology MH - Hemolysins/*analysis MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 751210 DP - 1974 Dec IS - 0048-0169 TA - N Z Vet J PG - 239-42 CY - NEW ZEALAND IP - 12 VI - 22 JC - OBZ EM - 7602 PMID- 4534015 CU - 88 SO - N Z Vet J 1974 Dec;22(12):239-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 75078014 AU - Morris JA AU - Hussaini SN TI - Characterization of the antibodies detected by the microscopic agglutination test for bovine leptospirosis. LA - Eng MH - *Agglutination Tests/methods MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial MH - Cattle MH - Cattle Diseases/*immunology MH - Centrifugation, Density Gradient MH - Chromatography, Gel MH - Chromatography, Ion Exchange MH - IgG/isolation & purification MH - IgM/isolation & purification MH - Immunoelectrophoresis MH - Leptospirosis/*immunology/*veterinary MH - Rabbits/immunology MH - Weil's Disease/immunology/veterinary PT - JOURNAL ARTICLE DA - 750414 DP - 1974 Dec IS - 0022-1724 TA - J Hyg (Lond) PG - 425-32 SB - M CY - ENGLAND IP - 3 VI - 73 JC - IEF EM - 7505 PMID- 4531451 CU - 88 SO - J Hyg (Lond) 1974 Dec;73(3):425-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 75167458 AU - Tsai CC AU - Fresh JW TI - Serological study of leptospirosis among farmers and farm helpers in central Taiwan. LA - Eng MH - Agglutination Tests MH - Agricultural Workers' Diseases/*blood MH - Female MH - Human MH - Leptospirosis/*blood MH - Male MH - Taiwan PT - JOURNAL ARTICLE DA - 750909 DP - 1974 Dec IS - 0009-4587 TA - Chung Hua Min Kuo Wei Sheng Wu Hsueh Tsa Chih PG - 176-7 SB - M CY - TAIWAN IP - 4 VI - 7 JC - D32 EM - 7510 PMID- 4480434 CU - 86 SO - Chung Hua Min Kuo Wei Sheng Wu Hsueh Tsa Chih 1974 Dec;7(4):176-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 75150096 AU - Leman AD AU - Cropper M AU - Rodeffer HE TI - Infectious swine reproductive diseases. LA - Eng MH - Animal MH - Brucellosis/veterinary MH - Eperythrozoonosis/veterinary MH - Female MH - Hog Cholera MH - Infertility/*veterinary MH - Influenza/veterinary MH - Leptospirosis/veterinary MH - Male MH - Pregnancy MH - Pregnancy Complications, Infectious/*veterinary MH - Pseudorabies/veterinary MH - Swine MH - *Swine Diseases MH - Toxoplasmosis, Animal PT - JOURNAL ARTICLE DA - 750807 DP - 1974 Dec IS - 0093-691X TA - Theriogenology PG - 149-60 CY - UNITED STATES IP - 6 VI - 2 JC - E68 EM - 7509 PMID- 4477541 CU - 90 LI - R SO - Theriogenology 1974 Dec;2(6):149-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 76068196 AU - Ryu E AU - Hasegawa A AU - Saegusa S AU - Ichiki H TI - An investigation of canine leptospiral antibodies in Tokyo and Yokohama. Comparison of Canine Positive rates between rapid microscopic agglutination test and Schuffner-Mochtar test. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Dogs/*immunology MH - Female MH - Japan MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Male MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 760220 DP - 1974 Dec TA - Int J Zoonoses PG - 82-90 SB - M CY - TAIWAN IP - 2 VI - 1 JC - GTK EM - 7604 PMID- 4468963 CU - 89 SO - Int J Zoonoses 1974 Dec;1(2):82-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 76028290 AU - Mori M AU - Arimitsu Y AU - Otani S AU - Akama K TI - Intracutaneous infection with Leptospira icterohaemorrhagiae (Shibaura strain) of the guinea pig. LA - Eng MH - Animal MH - Antibody Formation MH - Body Weight MH - Comparative Study MH - Guinea Pigs MH - Hemorrhage/etiology MH - Injections, Intraperitoneal MH - Injections, Subcutaneous MH - Leptospira interrogans/pathogenicity MH - Rabbits MH - Skin Diseases, Infectious/immunology/*pathology MH - Weil's Disease/immunology/*pathology PT - JOURNAL ARTICLE DA - 751223 DP - 1974 Dec IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 297-308 SB - M CY - JAPAN IP - 6 VI - 27 JC - KLZ AA - Author EM - 7602 AB - Experimental leptospirosis with Leptospira icterohaemorrhagiae Shibaura strain was studied in guinea pigs. When the pathogen was inoculated intracutaneously to the back of the animals, localized haemorrhage was observed at the inoculated site before the appearance of general haemorrhage. The severity of the local lesion increased progressively until the 7th day of inoculation. The minimum infective dose (MID) or the 50% infective dose (ID50) of the leptospiral suspension was determined by the appearance of the macroscopic local haemorrhage 7 days after inoculation. The MID thus determined was almost comparable with the value determined by the development of general symptoms and signs by conventional ip inoculation. The number of the pathogen per ID50 varied between 6 and 35 in five experiments. The local haemorrhage was effectively protected by active or passive immunization. Microscopically, haemorrhage at the inoculated site was found mainly in the dermis, directly beneath the epidermis in particular, and accompanied with leakage of the pathogen. The pathogen was also detected abunduntly in the thickened epidermal layer covering the inoculated area as well as in the epithelial matrix of hair-follicle, probably due to the proliferation of the pathogen at the site. PMID- 4466847 SO - Jpn J Med Sci Biol 1974 Dec;27(6):297-308 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 75129510 AU - Ramachandran S AU - Rajapakse CN AU - Perera MV TI - Changing patterns in leptospirosis in Sri Lanka. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Environmental Exposure MH - Female MH - Human MH - Leptospirosis/*epidemiology/mortality MH - Male MH - Middle Age MH - Occupations MH - Sri Lanka PT - JOURNAL ARTICLE DA - 750702 DP - 1974 Dec IS - 0009-0875 TA - Ceylon Med J PG - 142-9 CY - SRI LANKA IP - 3 VI - 19 JC - CY9 EM - 7508 PMID- 4457242 CU - 88 SO - Ceylon Med J 1974 Dec;19(3):142-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 75141705 AU - Cinco M AU - Crismani P TI - Thermolabile agglutinogens in saprophytic leptospirae. LA - Eng MH - Absorption MH - Agglutinins MH - Animal MH - Antibody Formation MH - Antigens, Bacterial/*analysis MH - Cross Reactions MH - Heat MH - Immune Sera MH - Immunization MH - Leptospira/*immunology MH - Rabbits MH - Serotyping PT - JOURNAL ARTICLE DA - 750620 DP - 1974 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 417-22 SB - M CY - NETHERLANDS IP - 4 VI - 26 JC - WGJ EM - 7508 PMID- 4456701 SO - Trop Geogr Med 1974 Dec;26(4):417-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 75077332 AU - Smith AW AU - Brown RJ AU - Skilling DE AU - DeLong RL TI - Leptospira pomona and reproductive failure in California sea lions. LA - Eng MH - Abortion, Veterinary/*etiology/immunology/microbiology MH - Agglutination Tests MH - Animal MH - California MH - Fatty Liver/veterinary MH - Female MH - Fetal Death/etiology/microbiology/veterinary MH - Fetal Diseases/etiology/microbiology/veterinary MH - Hemorrhage/veterinary MH - Kidney/microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/etiology/immunology/microbiology/*veterinary MH - Liver/microbiology MH - Nephritis, Interstitial/microbiology/veterinary MH - *Pinnipedia MH - Placenta/microbiology MH - Pregnancy PT - JOURNAL ARTICLE DA - 750326 DP - 1974 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 996-8 SB - M CY - UNITED STATES IP - 11 VI - 165 JC - HAV EM - 7505 PMID- 4443311 SO - J Am Vet Med Assoc 1974 Dec 1;165(11):996-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75060269 AU - Livermore BP AU - Johnson RC TI - Lipids of the Spirochaetales: comparison of the lipids of several members of the genera Spirochaeta, Treponema, and Leptospira. LA - Eng MH - Chromatography, Gas MH - Chromatography, Thin Layer MH - Comparative Study MH - Diglycerides/metabolism MH - Fatty Acids/biosynthesis/metabolism MH - Glycolipids/metabolism MH - Leptospira/*metabolism MH - Lipids/*metabolism MH - Oxidation-Reduction MH - Phosphatidylcholines/metabolism MH - Phosphatidylethanolamines/metabolism MH - Phospholipids/metabolism MH - Species Specificity MH - Spectrophotometry MH - Spirochaeta/*metabolism MH - Treponema/*metabolism PT - JOURNAL ARTICLE DA - 750227 DP - 1974 Dec IS - 0021-9193 TA - J Bacteriol PG - 1268-73 SB - M CY - UNITED STATES IP - 3 VI - 120 JC - HH3 EM - 7504 PMID- 4436256 CU - 90 SO - J Bacteriol 1974 Dec;120(3):1268-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [10 medline neighbors] UI - 75091558 AU - Oriel JD AU - Hayward AH TI - Sexually-transmitted diseases in animals. LA - Eng MH - Animal MH - Brucellosis/transmission MH - Cattle MH - Cattle Diseases/*transmission MH - Chlamydia Infections/veterinary MH - Dog Diseases/*transmission MH - Dogs MH - Female MH - Herpesviridae Infections/veterinary MH - Human MH - Leptospirosis/veterinary MH - Male MH - Mycoplasma Infections/veterinary MH - Papilloma/veterinary MH - Penile Neoplasms/veterinary MH - Poxviridae Infections/veterinary MH - Salmonella Infections, Animal/transmission MH - Sexually Transmitted Diseases/*veterinary MH - Sheep MH - Sheep Diseases/*transmission MH - Trichomonas Infections/veterinary MH - Trypanosomiasis/veterinary MH - Vibrio Infections/veterinary PT - JOURNAL ARTICLE DA - 750513 DP - 1974 Dec IS - 0007-134X TA - Br J Vener Dis PG - 412-20 SB - M CY - ENGLAND IP - 6 VI - 50 JC - B40 EM - 7506 PMID- 4374988 CU - 93 SO - Br J Vener Dis 1974 Dec;50(6):412-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75059637 AU - Yanagawa R AU - Takashima I TI - Conversion of serotype in Leptospira from hebdomadis to kremastos. LA - Eng MH - Absorption MH - Agglutination Tests MH - Agglutinins MH - Animal MH - Bacteriological Techniques MH - Immune Sera MH - Immunodiffusion MH - *Leptospira/classification MH - *Mutation MH - Rabbits/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 750220 DP - 1974 Dec IS - 0019-9567 TA - Infect Immun PG - 1439-42 SB - M CY - UNITED STATES IP - 6 VI - 10 JC - GO7 EM - 7504 PMID- 4215766 CU - 91 SO - Infect Immun 1974 Dec;10(6):1439-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [17 medline neighbors] UI - 75040974 AU - Sweeney JC TI - Common diseases of pinnipeds. LA - Eng MH - Alopecia/veterinary MH - Animal MH - Animals, Zoo MH - Ataxia/veterinary MH - Cestode Infections/veterinary MH - Colitis/veterinary MH - Dermatitis/veterinary MH - Dirofilariasis/veterinary MH - Erysipelothrix Infections MH - Female MH - Hepatitis, Animal MH - Hypoglycemia/veterinary MH - Intestinal Diseases, Parasitic/veterinary MH - Labor Complications/veterinary MH - Leptospirosis/veterinary MH - Lung Diseases, Parasitic/veterinary MH - Male MH - Metastrongyloidea MH - Mite Infestations/veterinary MH - Mycoses/veterinary MH - Nematode Infections/veterinary MH - Neoplasms/veterinary MH - Pediculosis/veterinary MH - *Pinnipedia MH - Pregnancy MH - Skin Diseases/veterinary MH - Stomach Ulcer/veterinary MH - Tooth Extraction/veterinary MH - Trematode Infections/veterinary MH - Wounds and Injuries/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 750127 DP - 1974 Nov 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 805-10 SB - M CY - UNITED STATES IP - 9 VI - 165 JC - HAV EM - 7503 RF - 29 PMID- 4609963 CU - 90 SO - J Am Vet Med Assoc 1974 Nov 1;165(9):805-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 75064543 AU - Berger SA AU - Oliver JA AU - Pulini M TI - Urban leptospirosis. LA - Eng MH - Adult MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - New York City MH - Urban Population PT - JOURNAL ARTICLE DA - 750310 DP - 1974 Nov IS - 0028-7628 TA - N Y State J Med PG - 2232-3 CY - UNITED STATES IP - 12 VI - 74 JC - OBA EM - 7504 PMID- 4530914 CU - 88 SO - N Y State J Med 1974 Nov;74(12):2232-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 75161411 AU - Reinschke P TI - [Acute kidney failure in leptospirosis] LA - Ger MH - Adult MH - Female MH - Hemodialysis MH - Human MH - Kidney Failure, Acute/complications/*therapy MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*complications/diagnosis/drug therapy MH - Male MH - Middle Age MH - Nephritis, Interstitial/complications MH - Oxytetracycline/therapeutic use MH - Time Factors PT - JOURNAL ARTICLE DA - 750724 DP - 1974 Nov TA - Z Urol Nephrol PG - 823-7 SB - M CY - GERMANY, EAST IP - 11 VI - 67 JC - Y1W EM - 7509 PMID- 4460595 CU - 90 TT - Die Behandlung der akuten Niereninsuffizienz bei Leptospirosen SO - Z Urol Nephrol 1974 Nov;67(11):823-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 75105353 AU - Ezhov GI AU - Kiktenko VS AU - Berezov TT TI - [Dissociation of Leptospira] LA - Rus MH - Animal MH - *Cell Differentiation MH - Culture Media MH - Leptospira/*cytology MH - Leptospirosis/veterinary MH - Swine MH - Swine Diseases/microbiology MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 750509 DP - 1974 Nov TA - Zh Mikrobiol Epidemiol Immunobiol PG - 139 SB - M CY - USSR IP - 11 JC - Y9O EM - 7506 PMID- 4450857 CU - 89 TT - K voprosu o dissotsiatsii leptospir. SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Nov;(11):139 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 75091574 AU - Shigidi MT TI - Animal leptospirosis in the Sudan. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/isolation & purification MH - Camels MH - Dog Diseases/epidemiology MH - Dogs MH - Goats MH - Leptospira/immunology MH - Leptospirosis/epidemiology/*veterinary MH - Mice MH - Rodentia MH - Sheep MH - Sheep Diseases/epidemiology MH - Sudan PT - JOURNAL ARTICLE DA - 750513 DP - 1974 Nov-Dec IS - 0007-1935 TA - Br Vet J PG - 528-31 CY - ENGLAND IP - 6 VI - 130 JC - B5C EM - 7506 PMID- 4447872 CU - 88 SO - Br Vet J 1974 Nov-Dec;130(6):528-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 75105352 AU - Tagi-Zade TA AU - Alekperov FP AU - Dzhabrailova FB AU - Gadzhiev IA TI - [Pone tortoises (Emys orbicularis) as a possible source of Leptospira infection] LA - Rus MH - Animal MH - Azerbaijan MH - *Disease Reservoirs MH - Leptospira/*isolation & purification MH - Turtles/*microbiology PT - JOURNAL ARTICLE DA - 750509 DP - 1974 Nov TA - Zh Mikrobiol Epidemiol Immunobiol PG - 138 SB - M CY - USSR IP - 11 JC - Y9O EM - 7506 PMID- 4281241 CU - 92 TT - Bolotnye cherepakhi (Emys orbicularis)-vozmozhnyi istochnik leptospiroznoi infektsii. SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Nov;(11):138 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 75100015 AU - Podboronov VM AU - Stepanchenok-Rudnik GI AU - Grokhovskaia IM TI - [Study of the antibacterial effect of organs and tissues of the tick Hyalomma asiaticum (Ixodidae)] LA - Rus MH - Animal MH - *Antibiosis MH - Antibiotics/*isolation & purification MH - Bacillus subtilis MH - Brucella MH - Corynebacterium diphtheriae MH - English Abstract MH - Erysipelothrix MH - Escherichia coli MH - Hemolymph MH - Intestines MH - Leptospira MH - Listeria monocytogenes MH - Pasteurella MH - Salmonella typhimurium MH - Staphylococcus MH - *Ticks PT - JOURNAL ARTICLE DA - 750513 DP - 1974 Nov-Dec IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 715-9 CY - USSR IP - 6 VI - 43 JC - M72 EM - 7506 PMID- 4217426 CU - 91 TT - Izuchenie antibakterial'nogo deistviia organov i tkanei kleshchei Hyalomma asiaticum (Ikhodidae) EA - A SO - Med Parazitol (Mosk) 1974 Nov-Dec;43(6):715-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 75142047 AU - Androsov VA TI - [Effectiveness of a specific gamma-globulin in leptospirosis of swine] LA - Rus MH - Animal MH - Gamma-Globulins/*administration & dosage MH - Leptospirosis/immunology/*veterinary MH - Swine/immunology MH - Swine Diseases/*immunology PT - JOURNAL ARTICLE DA - 750618 DP - 1974 Nov IS - 0042-4846 TA - Veterinariia PG - 70-1 CY - USSR IP - 11 JC - XCC EM - 7508 PMID- 4142151 CU - 95 TT - Effektivnost; spetsificheskogo gamma-globulina pri leptospiroze svinei SO - Veterinariia 1974 Nov;(11):70-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 75097461 AU - Marshall RB TI - Ultrastructural changes in renal tubules of sheep following experimental infection with Leptospira interrogans serotype pomona. LA - Eng MH - Animal MH - Cell Membrane/ultrastructure MH - Cell Nucleus/ultrastructure MH - Female MH - Injections, Intraperitoneal MH - Kidney Tubules/microbiology/*ultrastructure MH - Leptospirosis/pathology/*veterinary MH - Lysosomes/ultrastructure MH - Microscopy, Electron MH - Mitochondria/ultrastructure MH - Necrosis/pathology MH - Serotyping MH - Sheep MH - Sheep Diseases/*pathology MH - Staining PT - JOURNAL ARTICLE DA - 750513 DP - 1974 Nov IS - 0022-2615 TA - J Med Microbiol PG - 505-8 SB - M CY - ENGLAND IP - 4 VI - 7 JC - J2N EM - 7506 PMID- 4141375 CU - 95 SO - J Med Microbiol 1974 Nov;7(4):505-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [11 medline neighbors] UI - 75060044 AU - Sprecher DJ AU - Leman AD AU - Dziuk PD AU - Cropper M AU - DeDecker M TI - Causes and control of swine stillbirths. LA - Eng MH - Animal MH - Anoxia/veterinary MH - Birth Order MH - Carbachol/pharmacology MH - Corticotropin/pharmacology MH - Dexamethasone/pharmacology MH - Dichlorvos/pharmacology MH - Enterovirus Infections/veterinary MH - Female MH - Fetal Death/etiology/prevention & control/*veterinary MH - Hemoglobins/analysis MH - Labor Complications/veterinary MH - Leptospirosis/veterinary MH - Oxytocin/pharmacology MH - Parvoviridae MH - Pregnancy MH - Prostaglandins/pharmacology MH - Rupture MH - Streptococcal Infections/veterinary MH - Stress/veterinary MH - Swine MH - *Swine Diseases/etiology/prevention & control MH - Umbilical Cord MH - Virus Diseases/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 750319 DP - 1974 Oct 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 698-701 SB - M CY - UNITED STATES IP - 8 VI - 165 JC - HAV EM - 7504 RF - 45 PMID- 4373424 CU - 93 SO - J Am Vet Med Assoc 1974 Oct 15;165(8):698-701 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [14 medline neighbors] UI - 75060041 AU - Zemjanis R TI - Vaccination for reproductive efficiency in cattle. LA - Eng MH - Abortion, Veterinary/immunology/prevention & control MH - Animal MH - Bacterial Vaccines MH - Brucella abortus/immunology MH - Brucellosis, Bovine/prevention & control MH - Campylobacter fetus/immunology MH - Cattle/*physiology MH - Cattle Diseases/immunology/prevention & control MH - Chlamydia Infections/prevention & control/veterinary MH - Female MH - Infectious Bovine Rhinotracheitis/prevention & control MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospirosis/immunology/prevention & control/veterinary MH - Paramyxoviridae Infections/prevention & control/veterinary MH - Pregnancy MH - *Reproduction MH - Rickettsial Vaccines MH - Vaccination/*veterinary MH - Vibrio Infections/prevention & control/veterinary MH - Viral Vaccines PT - JOURNAL ARTICLE PT - REVIEW DA - 750319 DP - 1974 Oct 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 689-92 SB - M CY - UNITED STATES IP - 8 VI - 165 JC - HAV EM - 7504 RF - 43 RO - M:NES PMID- 4373423 LR - 940617 CU - 96 SO - J Am Vet Med Assoc 1974 Oct 15;165(8):689-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 75075613 AU - Budak AP TI - [Leptospirosis and measures of prevention] LA - Rus MH - Human MH - Leptospirosis/*prevention & control PT - JOURNAL ARTICLE DA - 750417 DP - 1974 Oct TA - Feldsher Akush PG - 7-10 SB - N CY - USSR IP - 10 VI - 39 JC - EVA EM - 7505 PMID- 4497796 CU - 89 LI - N TT - Leptospirozy i mery ikh profilaktiki. SO - Feldsher Akush 1974 Oct;39(10):7-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 75123479 AU - Malakhov IuA TI - [Leptospirosis--problems and opinions] LA - Rus MH - Animal MH - Disease Reservoirs MH - Leptospira/classification MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 750529 DP - 1974 Oct IS - 0042-4846 TA - Veterinariia PG - 65-8 CY - USSR IP - 10 JC - XCC EM - 7507 PMID- 4454234 TT - Leptospiroz--problemy i suzhdeniia SO - Veterinariia 1974 Oct;(10):65-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 75090048 AU - Dobson KJ TI - Letter: Eradication of leptospirosis in commercial pig herds. LA - Eng MH - Animal MH - Female MH - Leptospirosis/drug therapy/therapy/*veterinary MH - Male MH - Streptomycin/*therapeutic use MH - Swine MH - Swine Diseases/drug therapy/*therapy MH - *Vaccination PT - JOURNAL ARTICLE DA - 750411 DP - 1974 Oct IS - 0005-0423 TA - Aust Vet J PG - 471 SB - M CY - AUSTRALIA IP - 10 VI - 50 JC - 9IE EM - 7505 PMID- 4447531 SO - Aust Vet J 1974 Oct;50(10):471 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 75078278 AU - Sitprija V TI - Interstitial nephritis in infection. LA - Eng MH - Adult MH - Human MH - Kidney Function Tests MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Nephritis, Interstitial/*etiology MH - Scrub Typhus/*complications PT - JOURNAL ARTICLE DA - 750408 DP - 1974 Oct IS - 0025-7036 TA - J Med Assoc Thai PG - 517-20 CY - THAILAND IP - 10 VI - 57 JC - IZR EM - 7505 PMID- 4443663 SO - J Med Assoc Thai 1974 Oct;57(10):517-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 75062144 AU - Glosser JW AU - Sulzer CR AU - Eberhardt M AU - Winkler WG TI - Cultural and serologic evidence of Leptospira interrogans serotype Tarassovi infection in turtles. LA - Eng MH - Agglutination Tests MH - Animal MH - Brain/microbiology MH - Cloaca/microbiology MH - Hamsters MH - Kidney/microbiology MH - Leptospira/immunology/isolation & purification/microbiology MH - Leptospirosis/immunology/*veterinary MH - Male MH - *Turtles MH - Water Microbiology PT - JOURNAL ARTICLE DA - 750318 DP - 1974 Oct IS - 0090-3558 TA - J Wildl Dis PG - 429-35 SB - M CY - UNITED STATES IP - 4 VI - 10 JC - KEM EM - 7504 PMID- 4436929 SO - J Wildl Dis 1974 Oct;10(4):429-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 75062126 AU - Woods FN TI - Leptospira interrogans in the Ballum serogroup from a vole, Microtus oeconomus (Pallas) in Alaska. LA - Eng MH - Agglutination Tests MH - Alaska MH - Animal MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Rodent Diseases/*microbiology MH - Rodentia PT - JOURNAL ARTICLE DA - 750318 DP - 1974 Oct IS - 0090-3558 TA - J Wildl Dis PG - 325-6 SB - M CY - UNITED STATES IP - 4 VI - 10 JC - KEM EM - 7504 PMID- 4436918 SO - J Wildl Dis 1974 Oct;10(4):325-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 75043649 AU - Kitaoka M AU - Ishimaru M TI - Geographical distribution of leptospira-positive field rodents in Japan. LA - Eng MH - Animal MH - Japan MH - Kidney/pathology MH - Leptospirosis/*veterinary MH - Male MH - *Rodentia PT - JOURNAL ARTICLE DA - 750206 DP - 1974 Oct IS - 0021-5112 TA - Jpn J Med Sci Biol PG - 277-84 SB - M CY - JAPAN IP - 5 VI - 27 JC - KLZ EM - 7503 PMID- 4431099 SO - Jpn J Med Sci Biol 1974 Oct;27(5):277-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75040422 AU - Kadis S AU - Pugh WL TI - Urea utilization by Leptospira. LA - Eng MH - Ammonium Chloride/metabolism MH - Culture Media MH - Genotype MH - Hydrogen-Ion Concentration MH - Leptospira/enzymology/growth & development/*metabolism MH - Urea/*metabolism MH - Urease/metabolism PT - JOURNAL ARTICLE DA - 750204 DP - 1974 Oct IS - 0019-9567 TA - Infect Immun PG - 793-801 SB - M CY - UNITED STATES IP - 4 VI - 10 JC - GO7 EM - 7503 PMID- 4426709 SO - Infect Immun 1974 Oct;10(4):793-801 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [5 medline neighbors] UI - 75062134 AU - Sweeney JC AU - Gilmartin WG TI - Survey of diseases in free-living California sea lions. LA - Eng MH - Abscess/veterinary MH - Animal MH - Antibiotics/therapeutic use MH - California MH - Colitis/veterinary MH - Escherichia coli Infections/microbiology MH - Female MH - Kidney/abnormalities MH - Klebsiella Infections/microbiology MH - Leptospirosis/veterinary MH - Levamisole/therapeutic use MH - Lung Diseases, Parasitic/drug therapy/veterinary MH - Male MH - Metastrongyloidea MH - Nematode Infections/drug therapy/veterinary MH - Nephritis/veterinary MH - Nephroblastoma/veterinary MH - Peritonitis/veterinary MH - *Pinnipedia MH - Pneumonia/drug therapy/veterinary MH - Spleen/abnormalities MH - Stomach Diseases/veterinary MH - Stomach Ulcer/veterinary PT - JOURNAL ARTICLE DA - 750318 DP - 1974 Oct IS - 0090-3558 TA - J Wildl Dis PG - 370-6 SB - M CY - UNITED STATES IP - 4 VI - 10 JC - KEM EM - 7504 PMID- 4373587 CU - 93 SO - J Wildl Dis 1974 Oct;10(4):370-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 76080317 AU - Nicolescu M AU - Moldoveanu G TI - [Status of human leptospirosis in Rumania in the period 1967-1971] LA - Rum MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Child MH - Child, Preschool MH - English Abstract MH - Human MH - Infant MH - Leptospirosis/*epidemiology MH - Middle Age MH - Romania MH - Seasons MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 760301 DP - 1974 Oct-Dec IS - 0376-4494 TA - Rev Ig [Bacteriol] PG - 375-82 SB - M CY - ROMANIA IP - 5 VI - 19 JC - S7C EM - 7604 PMID- 4283329 CU - 92 TT - Situatia leptospirozelor umane in Romania in perioada 1967-1971 EA - A SO - Rev Ig [Bacteriol] 1974 Oct-Dec;19(5):375-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75123480 AU - Adamovich VL AU - Goriainov PI TI - [Model of an anthropurgic focus of leptospirosis] LA - Rus MH - Animal MH - Human MH - Leptospirosis/epidemiology/*veterinary MH - *Models, Theoretical MH - Russia MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 750529 DP - 1974 Oct IS - 0042-4846 TA - Veterinariia PG - 68-70 CY - USSR IP - 10 JC - XCC EM - 7507 PMID- 4281566 CU - 92 TT - Model' antropurgicheskogo ochaga leptospiroza SO - Veterinariia 1974 Oct;(10):68-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75123477 AU - Liubashenko SIa AU - Seregin IG AU - Akhmedov MM AU - Bolotskii IA AU - Sidnevets PP TI - [Serological characteristics of Leptospira strains] LA - Rus MH - Animal MH - Cattle MH - Dogs MH - Leptospira/*immunology MH - Leptospirosis/*veterinary MH - Rodentia MH - Russia MH - Serotyping PT - JOURNAL ARTICLE DA - 750529 DP - 1974 Oct IS - 0042-4846 TA - Veterinariia PG - 61-2 CY - USSR IP - 10 JC - XCC EM - 7507 PMID- 4281565 CU - 92 TT - Serologicheskiaia kharakteristika shtammov leptospir SO - Veterinariia 1974 Oct;(10):61-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [16 medline neighbors] UI - 75086747 AU - Archer RK TI - International control of equine infectious diseases. LA - Eng MH - Abortion, Veterinary/prevention & control MH - Adenoviridae Infections/veterinary MH - African Horsesickness/prevention & control MH - Animal MH - Arteritis/veterinary MH - Brucellosis/veterinary MH - Encephalitis Virus, Venezuelan Equine MH - Encephalomyelitis, Equine/veterinary MH - Equine Infectious Anemia/prevention & control MH - Exanthema/veterinary MH - Female MH - Herpesviridae Infections/veterinary MH - Horse Diseases/*prevention & control MH - Horses MH - Influenza/veterinary MH - *International Cooperation MH - Klebsiella Infections/veterinary MH - Leptospirosis/veterinary MH - Male MH - Pregnancy MH - Rabies/veterinary MH - Respiratory Tract Infections/veterinary MH - Rhinovirus MH - Tinea/veterinary MH - Virus Diseases/veterinary PT - JOURNAL ARTICLE DA - 750423 DP - 1974 Sep 21 IS - 0042-4900 TA - Vet Rec PG - 248-51 SB - M CY - ENGLAND IP - 12 VI - 95 JC - XBS EM - 7505 PMID- 4374790 CU - 93 SO - Vet Rec 1974 Sep 21;95(12):248-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 75082798 AU - Hodges RT TI - Some observations on experimental Leptospira serotype Pomona infection in sheep. LA - Eng MH - Animal MH - Leptospirosis/blood/immunology/pathology/*veterinary MH - Male MH - Sheep MH - *Sheep Diseases/blood/immunology/pathology PT - JOURNAL ARTICLE DA - 750417 DP - 1974 Sep IS - 0048-0169 TA - N Z Vet J PG - 151-4 CY - NEW ZEALAND IP - 9 VI - 22 JC - OBZ EM - 7505 PMID- 4531603 CU - 88 SO - N Z Vet J 1974 Sep;22(9):151-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 74306299 AU - Kerr DD AU - Marshall V TI - Protection against the renal carrier state by a canine leptospirosis vaccine. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Carrier State/prevention & control/*veterinary MH - Dog Diseases/*prevention & control MH - Dogs MH - Kidney Diseases/prevention & control/*veterinary MH - Leptospirosis/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 741108 DP - 1974 Sep IS - 0042-4889 TA - Vet Med Small Anim Clin PG - 1157-60 CY - UNITED STATES IP - 9 VI - 69 JC - XBO EM - 7412 RO - O:45 RO - C:00 PMID- 4496608 CU - 87 SO - Vet Med Small Anim Clin 1974 Sep;69(9):1157-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 75113999 AU - Tumilowicz JJ AU - Alexander AD AU - Stafford K TI - On the contamination of cell cultures by Leptospira biflexa. LA - Eng MH - Agglutination Tests MH - Animal MH - *Cell Line MH - Culture Media MH - Fresh Water MH - Hamsters MH - Kidney/microbiology/ultrastructure MH - Leptospira/*isolation & purification/ultrastructure MH - Methods MH - Microscopy, Electron MH - Species Specificity PT - JOURNAL ARTICLE DA - 750527 DP - 1974 Sep-Oct IS - 0073-5655 TA - In Vitro PG - 238-42 SB - M CY - UNITED STATES IP - 3-4 VI - 10 JC - GHD EM - 7507 PMID- 4476725 CU - 90 SO - In Vitro 1974 Sep-Oct;10(3-4):238-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 75140393 AU - Cunha Lima DP AU - Santa Rosa CA TI - [Serologic survey of leptospira in Rio Grande do Norte] LA - Por MH - Adult MH - Brazil MH - English Abstract MH - Female MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*epidemiology/immunology MH - Male PT - JOURNAL ARTICLE DA - 750627 DP - 1974 Sep-Oct IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 259-64 CY - BRAZIL IP - 5 VI - 16 JC - S9D EM - 7508 PMID- 4458026 CU - 88 TT - Inquerito sorlogogico para leptospirose no Rio Grande do Norte EA - A SO - Rev Inst Med Trop Sao Paulo 1974 Sep-Oct;16(5):259-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 75069959 AU - Ezhov GI AU - Berezov TT AU - Kiktenko VS TI - [Nucleic acid content and the nucleotide makeup of the RNA in certain strains of Leptospira] LA - Rus MH - Chromatography, Paper MH - Culture Media MH - DNA, Bacterial/*analysis MH - English Abstract MH - Leptospira/*analysis MH - Leptospira interrogans/analysis MH - Nucleotides/*analysis MH - RNA, Bacterial/*analysis MH - Serotyping MH - Spectrophotometry MH - Spectrophotometry, Ultraviolet MH - Time Factors PT - JOURNAL ARTICLE DA - 750227 DP - 1974 Sep TA - Zh Mikrobiol Epidemiol Immunobiol PG - 70-3 SB - M CY - USSR IP - 9 JC - Y9O EM - 7504 PMID- 4440340 CU - 90 TT - Soderzhanie nukleinovykh kislot i nukleotidnyi sostav RNK u nekotorykh shtammov leptospir EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Sep;(9):70-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [65 medline neighbors] UI - 75069929 AU - Moteiunas LI AU - Kovaleva LI AU - Ezerskene EP TI - [Spontaneous infection of a population of murine rodents by agents pathogenic to man in the Lithuanian SSR] LA - Rus MH - Animal MH - Bacterial Infections/*microbiology MH - Disease Reservoirs MH - English Abstract MH - Erysipelothrix Infections/microbiology MH - Human MH - Leptospirosis/microbiology MH - Listeria Infections/microbiology MH - Lithuania MH - Mice MH - Pasteurella Infections/microbiology MH - Rats MH - Rodent Diseases/*microbiology MH - Rodentia MH - Salmonella Infections, Animal/microbiology PT - JOURNAL ARTICLE DA - 750227 DP - 1974 Sep TA - Zh Mikrobiol Epidemiol Immunobiol PG - 122-3 SB - M CY - USSR IP - 9 JC - Y9O EM - 7504 PMID- 4440332 CU - 89 TT - Spontannaia zarazhenost' populiatsii myshevidnykh gryzunov patogennymi dlia cheloveka vozbuditeliami v Litovskoi SSR EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Sep;(9):122-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 75019175 AU - Brendle JJ AU - Alexander AD TI - Contamination of bacteriological media by Leptospira biflexa. LA - Eng MH - Agglutination Tests MH - Antigens, Bacterial/analysis MH - *Culture Media MH - Human MH - Immune Sera MH - Laboratories MH - Leptospira/immunology/*isolation & purification MH - Micropore Filters MH - Sterilization/methods MH - *Water Microbiology MH - *Water Supply PT - JOURNAL ARTICLE DA - 750110 DP - 1974 Sep IS - 0003-6919 TA - Appl Microbiol PG - 505-6 SB - M CY - UNITED STATES IP - 3 VI - 28 JC - 6K0 EM - 7502 PMID- 4417715 SO - Appl Microbiol 1974 Sep;28(3):505-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 75207576 AU - Mailloux CH AU - Mailloux M AU - Giraudeau P AU - Gilot Y AU - Saint-Andre P TI - [First case of confirmed leptospirosis in Mali] LA - Fre MH - Adolescence MH - Africa MH - Animal MH - Animals, Domestic MH - Antibodies, Viral/analysis MH - Antibody Formation MH - Antibody Specificity MH - Epitopes MH - Human MH - Leptospira interrogans/isolation & purification MH - Male MH - Mali MH - Serodiagnosis MH - Water Microbiology MH - Weil's Disease/*epidemiology/immunology/transmission MH - Zoonoses PT - JOURNAL ARTICLE DA - 751030 DP - 1974 Sep-Oct IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 498-503 SB - M CY - FRANCE IP - 5 VI - 67 JC - C4G EM - 7512 PMID- 4142867 CU - 95 TT - Premier cas de leptospirose confirmee au Mali SO - Bull Soc Pathol Exot Filiales 1974 Sep-Oct;67(5):498-503 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 75069871 AU - Kasai N AU - Yanagawa R TI - Studies on the antigenic determinant group of the type-specific antigen of Leptospira canicola. LA - Eng MH - Amino Acids/analysis MH - Antigens, Bacterial/*analysis MH - Arabinose/analysis MH - Carbohydrates/analysis MH - Chromatography, Paper MH - Complement Fixation Tests MH - *Epitopes MH - Galactose/analysis MH - Glucosamine/analysis MH - Hydrolysis MH - Immunodiffusion MH - Leptospira canicola/*immunology MH - Lipids/analysis MH - Lipopolysaccharides/analysis MH - Periodic Acid/pharmacology MH - Polysaccharides, Bacterial/analysis MH - Proteins/analysis MH - Rhamnose/analysis MH - Species Specificity MH - Uronic Acids/analysis MH - Xylose/analysis PT - JOURNAL ARTICLE DA - 750310 DP - 1974 Sep IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 533-41 SB - M CY - GERMANY, WEST IP - 4 VI - 228 JC - Y52 EM - 7504 RO - M:NES PMID- 4140640 LR - 940617 CU - 95 SO - Zentralbl Bakteriol [Orig A] 1974 Sep;228(4):533-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 75089980 AU - Graves S AU - Faine S TI - subsurface location of non-agglutinating antigens of Leptospira interrogans (serotype Biflexa). LA - Eng MH - Agglutination Tests MH - Alcohol, Ethyl MH - Animal MH - Antibody Specificity MH - Antigens, Bacterial/*analysis MH - Binding Sites, Antibody MH - Cell Membrane/immunology MH - Fluorescent Antibody Technique MH - Goats/immunology MH - Leptospira/*immunology MH - Precipitins/*analysis MH - Rabbits/immunology PT - JOURNAL ARTICLE DA - 750416 DP - 1974 Aug IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 631-7 SB - M CY - AUSTRALIA IP - 4 VI - 52 JC - 9FW EM - 7505 PMID- 4614775 CU - 90 SO - Aust J Exp Biol Med Sci 1974 Aug;52(4):631-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 75062588 AU - Pietruschka G AU - Hergt R TI - [Contribution to leptospirosis uveitis (author's transl)] LA - Ger MH - Adult MH - Agglutination Tests MH - Animal MH - Child MH - Disease Vectors MH - English Abstract MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*complications/drug therapy/immunology MH - Male MH - Middle Age MH - Oxytetracycline/therapeutic use MH - Penicillins/therapeutic use MH - Uveitis/drug therapy/*microbiology PT - JOURNAL ARTICLE DA - 750310 DP - 1974 Aug IS - 0023-2165 TA - Klin Monatsbl Augenheilkd PG - 279-85 SB - M CY - GERMANY, WEST IP - 2 VI - 165 JC - KWA EM - 7504 PMID- 4474566 CU - 85 TT - Beitrag zur Leptospiroseuveitis EA - A SO - Klin Monatsbl Augenheilkd 1974 Aug;165(2):279-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75105400 AU - Batkov IV TI - [Detection of leptospirosis in Turkmenia] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology MH - Turkmenistan PT - JOURNAL ARTICLE DA - 750509 DP - 1974 Aug TA - Zh Mikrobiol Epidemiol Immunobiol PG - 143-4 SB - M CY - USSR IP - 8 JC - Y9O EM - 7506 PMID- 4281245 CU - 92 TT - Vyiavlenie leptospiroza v Turkmenii. SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Aug;(8):143-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 75002072 AU - Silva AR da AU - Quadra AA AU - Quadra JA AU - Cordeiro HA de TI - [Epidemiological aspects of human leptospiroses in greater Rio de Janeiro, Brazil] LA - Spa MH - Adolescence MH - Adult MH - Aged MH - Brazil MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Infant MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 741217 DP - 1974 Aug IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 122-34 CY - UNITED STATES IP - 2 VI - 77 JC - AGG EM - 7501 PMID- 4277818 CU - 92 TT - Aspectos epidemiologicos das leptospiroses humanas no Grande Rio, Brasil EA - A SO - Bol Oficina Sanit Panam 1974 Aug;77(2):122-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 75089981 AU - Chang A AU - Faine S TI - Relative specificities of immunoglobulins reacting with axial filament antigens of Leptospira. LA - Eng MH - Animal MH - *Antibody Specificity MH - Antigen-Antibody Reactions MH - *Antigens, Bacterial MH - Centrifugation, Density Gradient MH - Chromatography, DEAE-Cellulose MH - Cross Reactions MH - Goats/immunology MH - Guinea Pigs/immunology MH - IgG MH - IgM MH - Immunodiffusion MH - Immunoelectrophoresis MH - *Immunoglobulins MH - Leptospira/*immunology MH - Mercaptoethanol MH - Rabbits/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 750416 DP - 1974 Aug IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 639-46 SB - M CY - AUSTRALIA IP - 4 VI - 52 JC - 9FW EM - 7505 PMID- 4217168 CU - 91 SO - Aust J Exp Biol Med Sci 1974 Aug;52(4):639-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 75089979 AU - Graves S AU - Faine S TI - trypsin extractable precipitating antigens of Leptospira interrogans (serotype Biflexa). LA - Eng MH - Adsorption MH - Animal MH - Antibodies, Bacterial/biosynthesis MH - Antibody Specificity MH - *Antigens, Bacterial/analysis/isolation & purification MH - Dialysis MH - Heat MH - Immunodiffusion MH - Immunoglobulins/analysis MH - Leptospira/cytology/*immunology MH - Microscopy, Electron MH - Papain MH - *Precipitins/analysis/isolation & purification MH - Rabbits MH - Time Factors MH - *Trypsin PT - JOURNAL ARTICLE DA - 750416 DP - 1974 Aug IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 615-29 SB - M CY - AUSTRALIA IP - 4 VI - 52 JC - 9FW EM - 7505 PMID- 4217167 CU - 91 SO - Aust J Exp Biol Med Sci 1974 Aug;52(4):615-29 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [78 medline neighbors] UI - 75028809 AU - Young JS AU - Blair JM TI - Perinatal calf losses in a beef herd. LA - Eng MH - Abnormalities/mortality/veterinary MH - Agglutination Tests MH - Animal MH - *Animals, Newborn MH - Antibodies, Bacterial/analysis MH - Bacteria/isolation & purification MH - Brucella abortus/immunology MH - Cattle MH - Cattle Diseases/immunology/microbiology/*mortality MH - Enteritis/mortality/veterinary MH - Female MH - Fetal Death/microbiology/*veterinary MH - Human MH - Labor Complications/mortality/veterinary MH - Leptospira/immunology MH - Maternal Age MH - Pregnancy MH - Time Factors PT - JOURNAL ARTICLE DA - 750106 DP - 1974 Aug IS - 0005-0423 TA - Aust Vet J PG - 338-44 SB - M CY - AUSTRALIA IP - 8 VI - 50 JC - 9IE EM - 7502 PMID- 4214120 CU - 91 SO - Aust Vet J 1974 Aug;50(8):338-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 74303337 AU - Cox PJ AU - Twigg GI TI - Leptospiral motility. LA - Eng MH - *Cell Movement MH - Culture Media MH - Leptospira/*physiology PT - JOURNAL ARTICLE DA - 741025 DP - 1974 Jul 19 IS - 0028-0836 TA - Nature PG - 260-1 SB - M CY - ENGLAND IP - 463 VI - 250 JC - NSC EM - 7412 RO - O:30 RO - C:25 PMID- 4852658 SO - Nature 1974 Jul 19;250(463):260-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 75011897 AU - Johnson RH AU - Allan PJ AU - Dennett DP TI - Letter: Leptospira hardjo with abortions in a group of heifers. LA - Eng MH - Abortion, Veterinary/*immunology MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Cattle Diseases/*immunology MH - Female MH - Leptospira/*immunology MH - Leptospirosis/veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 741219 DP - 1974 Jul IS - 0005-0423 TA - Aust Vet J PG - 325-6 SB - M CY - AUSTRALIA IP - 7 VI - 50 JC - 9IE EM - 7501 PMID- 4472179 CU - 85 SO - Aust Vet J 1974 Jul;50(7):325-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75027159 AU - Michna SW AU - Ellis W AU - Dikken H TI - The isolation of Leptospira hardjo from an aborting cow. LA - Eng MH - Abortion, Veterinary/etiology/*microbiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle/embryology/physiopathology MH - Cattle Diseases/*microbiology MH - Female MH - Immune Sera MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/physiopathology/veterinary MH - Male MH - Pregnancy MH - Rabbits/immunology PT - JOURNAL ARTICLE DA - 750113 DP - 1974 Jul IS - 0034-5288 TA - Res Vet Sci PG - 133-5 SB - M CY - ENGLAND IP - 1 VI - 17 JC - R7D EM - 7502 PMID- 4421529 SO - Res Vet Sci 1974 Jul;17(1):133-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 75012177 AU - Hogg GG TI - Letter: The isolation of Leptospira pomona from a sick foal. LA - Eng MH - Animal MH - Bacteriuria/microbiology/*veterinary MH - Horse Diseases/*microbiology MH - Horses MH - Leptospira/*isolation & purification PT - JOURNAL ARTICLE DA - 741219 DP - 1974 Jul IS - 0005-0423 TA - Aust Vet J PG - 326 SB - M CY - AUSTRALIA IP - 7 VI - 50 JC - 9IE EM - 7501 PMID- 4414429 SO - Aust Vet J 1974 Jul;50(7):326 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 75002070 AU - Schonberger W AU - Engelhardt K TI - [Epidemiologic studies on leptospirosis in childhood] LA - Ger MH - Age Factors MH - Agglutination Tests MH - Child MH - Germany, West MH - Human MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 741216 DP - 1974 Jul IS - 0026-9298 TA - Monatsschr Kinderheilkd PG - 445 SB - M CY - GERMANY, WEST IP - 7 VI - 122 JC - NH0 EM - 7501 PMID- 4409470 CU - 88 TT - Epidemiologische Untersuchungen zur Leptospirose im Kindesalter SO - Monatsschr Kinderheilkd 1974 Jul;122(7):445 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 74274687 AU - Cox CD AU - Barber MK TI - Oxygen uptake by Treponema pallidum. LA - Eng MH - Amobarbital/pharmacology MH - Anaerobiosis MH - Azides/pharmacology MH - Bacteriological Techniques MH - Chlorpromazine/pharmacology MH - Cyanides/pharmacology MH - Cytochrome-c Oxidase/metabolism MH - Dinitrophenols/pharmacology MH - Electron Transport/drug effects MH - Leptospira/metabolism MH - NAD/metabolism MH - Oxidative Phosphorylation/drug effects MH - *Oxygen Consumption MH - Quinolines MH - Rotenone MH - Spirochaeta/metabolism MH - Treponema pallidum/*metabolism PT - JOURNAL ARTICLE DA - 740919 DP - 1974 Jul IS - 0019-9567 TA - Infect Immun PG - 123-7 SB - M CY - UNITED STATES IP - 1 VI - 10 JC - GO7 EM - 7411 RO - O:31 RO - C:00 PMID- 4366918 CU - 93 SO - Infect Immun 1974 Jul;10(1):123-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 75026410 AU - Adachi Y TI - Studies on the determinant group of the type specific antigen of Leptospira kremastos strain Kyoto. LA - Eng MH - *Antigens, Bacterial MH - *Epitopes MH - Japan MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 750115 DP - 1974 Jul IS - 0047-1917 TA - Jpn J Vet Res PG - 97 CY - JAPAN IP - 3 VI - 22 JC - KRG EM - 7502 PMID- 4138521 CU - 95 SO - Jpn J Vet Res 1974 Jul;22(3):97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 74252673 AU - Szalka A AU - Binder L TI - [A rare case of human-to-human infection of leptospirosis] LA - Hun MH - Coitus MH - Female MH - Human MH - Leptospirosis/*etiology MH - Male PT - JOURNAL ARTICLE DA - 740822 DP - 1974 Jun 30 IS - 0030-6002 TA - Orv Hetil PG - 1531-2 CY - HUNGARY IP - 26 VI - 115 JC - OL8 EM - 7410 RO - O:14 RO - C:00 PMID- 4840706 TT - Leptospirosis emberrol emberre terjedo ritka esete SO - Orv Hetil 1974 Jun 30;115(26):1531-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 74309800 AU - Clair RE TI - Twenty-five years of infectious disease. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Diphtheria/epidemiology MH - Disease Outbreaks/epidemiology MH - Encephalitis/epidemiology MH - Female MH - Hepatitis A/epidemiology MH - *Hospitalization MH - Human MH - Infection/*epidemiology MH - Influenza/epidemiology MH - Leptospirosis/epidemiology MH - Male MH - Meningitis/epidemiology MH - New Zealand MH - Pneumonia, Staphylococcal/epidemiology MH - Poliomyelitis/epidemiology MH - Scarlet Fever/epidemiology MH - Tuberculosis/epidemiology MH - Typhoid/epidemiology PT - JOURNAL ARTICLE DA - 741107 DP - 1974 Jun 26 IS - 0028-8446 TA - N Z Med J PG - 1064-6 SB - M CY - NEW ZEALAND IP - 518 VI - 79 JC - OBQ EM - 7412 RO - O:00 RO - C:00 PMID- 4528095 CU - 88 SO - N Z Med J 1974 Jun 26;79(518):1064-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 74260660 AU - Marshall V AU - Kerr DD TI - Early protection of dogs by a leptospira bacterin. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Blood/microbiology MH - Dog Diseases/microbiology/*prevention & control MH - Dogs MH - Kidney/microbiology MH - Leptospira canicola/*immunology/isolation & purification MH - Leptospira interrogans/*immunology/isolation & purification MH - Leptospirosis/microbiology/prevention & control/*veterinary MH - Urine/microbiology MH - Vaccination PT - JOURNAL ARTICLE DA - 740821 DP - 1974 Jun IS - 0026-8542 TA - Mod Vet Pract PG - 430-2 SB - M CY - UNITED STATES IP - 6 VI - 55 JC - NGO EM - 7410 RO - O:45 RO - C:00 PMID- 4857980 CU - 85 SO - Mod Vet Pract 1974 Jun;55(6):430-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 74176103 AU - Felsenfeld O AU - Wolf RH TI - The indirect immunoenzyme test for the detection of antibodies against North American Borreliae. II. Experiments with human sera. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Cross Reactions MH - Human MH - IgG MH - Immune Sera MH - Leptospirosis/immunology MH - Methods MH - *Peroxidases MH - Rabbits/immunology MH - Relapsing Fever/*diagnosis MH - *Serodiagnosis PT - JOURNAL ARTICLE DA - 740730 DP - 1974 Jun IS - 0002-9173 TA - Am J Clin Pathol PG - 844-8 SB - A SB - M CY - UNITED STATES IP - 6 VI - 61 JC - 3FK EM - 7409 PMID- 4857613 CU - 90 SO - Am J Clin Pathol 1974 Jun;61(6):844-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 74310128 AU - Reasoner DJ TI - Water pollution. Microbiology--detection of bacterial pathogens and their occurrence. LA - Eng MH - Animal MH - Birds MH - Cattle MH - Communicable Diseases/*epidemiology MH - Disease Outbreaks MH - Dogs MH - Fishes MH - Food Microbiology MH - Gastrointestinal Diseases/epidemiology MH - Human MH - Hungary MH - Israel MH - Leptospirosis/microbiology MH - Poultry MH - Salmonella Infections/epidemiology/immunology/microbiology MH - Sheep MH - Shigella/isolation & purification MH - Swine MH - Switzerland MH - Turtles MH - United States MH - *Water Microbiology MH - *Water Pollution PT - JOURNAL ARTICLE PT - REVIEW DA - 741118 DP - 1974 Jun IS - 0043-1303 TA - J Water Pollut Control Fed PG - 1395-408 CY - UNITED STATES IP - 6 VI - 46 JC - KDZ EM - 7412 RF - 89 RO - O:46 RO - C:01 PMID- 4605443 CU - 90 SO - J Water Pollut Control Fed 1974 Jun;46(6):1395-408 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 76068192 AU - Topacio TM AU - Gavino LG AU - Famatiga E AU - Suva M TI - Leptospirosis in animals and man in the Philppines. VIII. Serological incidence in native dogs. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Dogs/*immunology MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Philippines PT - JOURNAL ARTICLE DA - 760213 DP - 1974 Jun TA - Int J Zoonoses PG - 32-42 SB - M CY - TAIWAN IP - 1 VI - 1 JC - GTK EM - 7604 RO - M:MSH PMID- 4468962 LR - 800331 CU - 89 SO - Int J Zoonoses 1974 Jun;1(1):32-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 76068191 AU - Ryu E AU - Suh IS TI - The leptospiral agglutinin of Korean dogs and wild rats by employing filter paper and rapid microsocpic agglutination test. LA - Eng MH - Agglutinins/*analysis MH - Animal MH - Dog Diseases/immunology MH - Dogs/*immunology MH - Female MH - Korea MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/veterinary MH - Male MH - Rats/*immunology PT - JOURNAL ARTICLE DA - 760213 DP - 1974 Jun TA - Int J Zoonoses PG - 21-35 SB - M CY - TAIWAN IP - 1 VI - 1 JC - GTK EM - 7604 PMID- 4468961 CU - 89 SO - Int J Zoonoses 1974 Jun;1(1):21-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75142444 AU - Jones CJ TI - Preliminary report on the isolation of twelve leptospira serotypes in Barbados. LA - Eng MH - Animal MH - Animal Diseases/epidemiology MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology/transmission/veterinary MH - Serodiagnosis MH - Serotyping MH - West Indies PT - JOURNAL ARTICLE DA - 750620 DP - 1974 Jun IS - 0043-3144 TA - West Indian Med J PG - 65-8 CY - JAMAICA IP - 2 VI - 23 JC - XN4 EM - 7508 PMID- 4456825 CU - 88 SO - West Indian Med J 1974 Jun;23(2):65-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 75003050 AU - Anan'ina IuV AU - Zaitsev SV TI - [Leptospira virulence depending on the storage time under laboratory conditions] LA - Rus MH - Animal MH - Culture Media MH - Hamsters MH - Leptospira/*pathogenicity MH - Leptospirosis/microbiology MH - Rabbits MH - Rodentia MH - Serotyping MH - Sheep MH - Swine MH - Time Factors MH - *Tissue Preservation MH - *Virulence PT - JOURNAL ARTICLE DA - 741216 DP - 1974 Jun TA - Zh Mikrobiol Epidemiol Immunobiol PG - 132-3 SB - M CY - USSR IP - 6 VI - 51 JC - Y9O EM - 7501 PMID- 4409969 CU - 90 TT - Virulentnost' leptospir v zavisimosti ot srokov khraneniia v laboratornykh usloviiakh SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Jun;51(6):132-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [14 medline neighbors] UI - 75001892 AU - Kanareikina SK TI - [Effect of satellite microorganisms on the growth of Leptospira colonies] LA - Rus MH - Culture Media MH - Leptospira/drug effects/*growth & development MH - NAD/pharmacology MH - Sarcina/growth & development MH - Staphylococcus/growth & development MH - *Symbiosis PT - JOURNAL ARTICLE DA - 741216 DP - 1974 Jun TA - Zh Mikrobiol Epidemiol Immunobiol PG - 131-2 SB - M CY - USSR IP - 6 VI - 51 JC - Y9O EM - 7501 PMID- 4369548 CU - 93 TT - Vliianie mikroorganizmov-satellitov na rost kolonii leptospir SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Jun;51(6):131-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [23 medline neighbors] UI - 74260472 AU - McCoy RH TI - Bacterial diseases of bats: a review. LA - Eng MH - Animal MH - Bacterial Infections/*veterinary MH - Borrelia Infections/veterinary MH - *Chiroptera MH - Dysentery, Bacillary/veterinary MH - Escherichia coli Infections/veterinary MH - Leptospirosis/veterinary MH - Pasteurella Infections/veterinary MH - Pseudomonas Infections/veterinary MH - Salmonella Infections, Animal MH - Tuberculosis/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 740822 DP - 1974 Jun IS - 0023-6764 TA - Lab Anim Sci PG - 530-4 SB - M CY - UNITED STATES IP - 3 VI - 24 JC - KYS EM - 7410 RF - 54 RO - O:45 RO - C:29 PMID- 4365723 CU - 93 SO - Lab Anim Sci 1974 Jun;24(3):530-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 75030163 AU - Chang A AU - Faine S TI - "Incomplete subserotypes" and the cryptic axial filament antigen of Leptospira. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antigens, Bacterial MH - Cross Reactions MH - Immunodiffusion MH - Leptospira/cytology/*immunology MH - Microscopy, Electron MH - Rabbits/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 750106 DP - 1974 Jun IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 569-75 SB - M CY - AUSTRALIA IP - Pt 3 VI - 52 JC - 9FW EM - 7502 PMID- 4214191 CU - 91 SO - Aust J Exp Biol Med Sci 1974 Jun;52(Pt 3):569-75 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 75025578 AU - Palit A AU - Hamilton RC AU - Gulasekharam J TI - Further studies on leptospiral genus-specific antigen: its ultrastructure and immunochemistry. LA - Eng MH - Agglutination Tests MH - Amino Acids/analysis MH - Animal MH - Antigens, Bacterial/*analysis MH - Bacterial Proteins/analysis MH - Galactose/analysis MH - Hemagglutination Tests MH - Immunodiffusion MH - Leptospira/*immunology/ultrastructure MH - Lipids/analysis MH - Lipoproteins/analysis MH - Mannose/analysis MH - Microscopy, Electron MH - Phosphorus/analysis MH - Rabbits/immunology MH - Rhamnose/analysis MH - Sheep/immunology MH - Xylose/analysis PT - JOURNAL ARTICLE DA - 741228 DP - 1974 Jun IS - 0022-1287 TA - J Gen Microbiol PG - 223-36 SB - M CY - ENGLAND IP - 0 VI - 82 Pt. 2 JC - I87 EM - 7502 PMID- 4213929 CU - 91 SO - J Gen Microbiol 1974 Jun;82 Pt. 2(0):223-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 75032769 AU - Chang A AU - Faine S AU - Williams WT TI - Cross-reactivity of the axial filament antigen as a criterion for classification of Leptospira. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antigens, Bacterial MH - *Cross Reactions/drug effects MH - Epitopes MH - IgG MH - IgM MH - Immunodiffusion MH - Leptospira/*classification/immunology MH - Mercaptoethanol/pharmacology MH - Microscopy, Electron MH - Rabbits/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 750106 DP - 1974 Jun IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 549-68 SB - M CY - AUSTRALIA IP - Pt 3 VI - 52 JC - 9FW EM - 7502 PMID- 4138817 CU - 95 SO - Aust J Exp Biol Med Sci 1974 Jun;52(Pt 3):549-68 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 74299923 AU - Christmas BW AU - Bragger JM AU - Till DG TI - Dairy farm fever in New Zealand: isolation of L pomona and L hardjo from a local outbreak. LA - Eng MH - Blood/microbiology MH - Culture Media MH - *Disease Outbreaks MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*microbiology MH - New Zealand MH - Serotyping PT - JOURNAL ARTICLE DA - 741111 DP - 1974 May 8 IS - 0028-8446 TA - N Z Med J PG - 904-6 SB - M CY - NEW ZEALAND IP - 514 VI - 79 JC - OBQ EM - 7412 RO - O:45 RO - C:00 PMID- 4527728 CU - 88 SO - N Z Med J 1974 May 8;79(514):904-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 74299922 AU - Christmas BW AU - Tennent RB AU - Lindsay PG TI - Dairy farm fever in New Zealand: a local outbreak of human leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Agricultural Workers' Diseases/*epidemiology MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - *Dairying MH - Disease Outbreaks/*epidemiology MH - Disease Reservoirs/veterinary MH - Female MH - Housing, Animal MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Male MH - Middle Age MH - New Zealand MH - Time Factors PT - JOURNAL ARTICLE DA - 741111 DP - 1974 May 8 IS - 0028-8446 TA - N Z Med J PG - 901-4 SB - M CY - NEW ZEALAND IP - 514 VI - 79 JC - OBQ EM - 7412 RO - O:45 RO - C:00 PMID- 4527727 CU - 90 SO - N Z Med J 1974 May 8;79(514):901-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 74170158 AU - Glosser JW AU - Johnson RC AU - Sulzer CR AU - Auran NE TI - Immunogenic properties of a leptospiral outer envelope bacterin in hamsters and foxes. LA - Eng MH - Agglutination Tests MH - Animal MH - *Bacterial Vaccines/administration & dosage MH - Brain/microbiology MH - Cross Reactions MH - Culture Media MH - Foxes/*immunology MH - Guinea Pigs MH - Hamsters MH - Injections, Intramuscular MH - Kidney/microbiology MH - Leptospira canicola/growth & development/*immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/prevention & control/*veterinary MH - Liver/microbiology MH - Male MH - Vaccination PT - JOURNAL ARTICLE DA - 740722 DP - 1974 May IS - 0002-9645 TA - Am J Vet Res PG - 681-4 SB - M CY - UNITED STATES IP - 5 VI - 35 JC - 40C EM - 7409 PMID- 4830438 SO - Am J Vet Res 1974 May;35(5):681-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 75011560 AU - Sullivan ND TI - Leptospirosis in animals and man. LA - Eng MH - Abortion, Veterinary/epidemiology MH - Animal MH - Australia MH - Cat Diseases/epidemiology MH - Cats MH - Cattle MH - Cattle Diseases/epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - Female MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - *Leptospirosis/diagnosis/drug therapy/epidemiology/etiology/prevention & control/veterinary MH - Pregnancy MH - Streptomycin/therapeutic use MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 741205 DP - 1974 May IS - 0005-0423 TA - Aust Vet J PG - 216-23 SB - M CY - AUSTRALIA IP - 5 VI - 50 JC - 9IE EM - 7501 PMID- 4414082 CU - 88 SO - Aust Vet J 1974 May;50(5):216-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 75002071 AU - Engelhardt K AU - Schonberger W AU - Schonberger G TI - [Epidemiologic studies on the incidence of leptospirosis in childhood (author's transl)] LA - Ger MH - Adolescence MH - Age Factors MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Germany, West MH - Hemagglutination Tests MH - Human MH - Infant MH - Leptospira/isolation & purification MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/microbiology MH - Lymph Nodes/microbiology MH - Lymphadenitis/microbiology MH - Male MH - Mass Screening MH - Neck MH - Retrospective Studies PT - JOURNAL ARTICLE DA - 741206 DP - 1974 May IS - 0026-9298 TA - Monatsschr Kinderheilkd PG - 179-82 SB - M CY - GERMANY, WEST IP - 5 VI - 122 JC - NH0 EM - 7501 RO - M:NES PMID- 4409471 LR - 940617 CU - 88 TT - Epidemiologische Untersuchungen zur Leptospirose im Kindesalter EA - A SO - Monatsschr Kinderheilkd 1974 May;122(5):179-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [16 medline neighbors] UI - 75027526 AU - McIntyre N AU - Heathcote J TI - The laboratory in the diagnosis and management of viral hepatitis. LA - Eng MH - Acute Disease MH - Alkaline Phosphatase/blood MH - Aminotransferases/blood MH - Bilirubin/blood MH - Blood Coagulation Tests MH - Cholestasis/complications MH - Cytomegalovirus Infections/diagnosis MH - Diagnosis, Differential MH - Enzyme Tests MH - Hepatitis A/*diagnosis MH - Hepatitis B/*diagnosis MH - Hepatitis B Antibodies/analysis MH - Hepatitis B Antigens/isolation & purification MH - Human MH - Immunologic Techniques MH - Infectious Mononucleosis/diagnosis MH - Jaundice/diagnosis/enzymology MH - Leptospirosis/diagnosis MH - Lipids/blood MH - Lipoproteins/blood MH - Liver Function Tests MH - Prothrombin Time MH - Serum Albumin/analysis MH - Serum Globulins/analysis MH - Syphilis/diagnosis MH - Toxoplasmosis/diagnosis PT - JOURNAL ARTICLE PT - REVIEW DA - 750106 DP - 1974 May IS - 0300-5089 TA - Clin Gastroenterol PG - 317-36 CY - ENGLAND IP - 2 VI - 3 JC - DDH EM - 7502 RF - 71 PMID- 4371184 CU - 93 SO - Clin Gastroenterol 1974 May;3(2):317-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 75092175 AU - Sramkova L AU - Vanista J AU - Duniewicz M AU - Cerovova H AU - Lobkowicz F TI - [Differential diagnostics between leptospirosis and tick-born meningoencephalitis (author's transl)] LA - Cze MH - Adolescence MH - Adult MH - Child MH - Diagnosis, Differential MH - Encephalitis, Tick-Borne/*diagnosis MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis MH - Meningoencephalitis/*diagnosis PT - JOURNAL ARTICLE DA - 750506 DP - 1974 May IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 160-4 CY - CZECHOSLOVAKIA IP - 3 VI - 23 JC - CSH EM - 7506 PMID- 4280954 CU - 92 TT - K diferencialni diagnostice mezi leptospirozou a klistovou meningoencefalitidou EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1974 May;23(3):160-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 74176022 AU - Timoney JF AU - Sheahan BJ AU - Timoney PJ TI - Leptospira and infectious canine hepatitis (ICH) virus antibodies and nephritis in Dublin dogs. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/*analysis MH - Antibodies, Viral/*analysis MH - Dog Diseases/epidemiology/*immunology MH - Dogs MH - Hepatitis, Infectious Canine/epidemiology/*immunology MH - Ireland MH - Kidney/pathology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Nephritis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 740730 DP - 1974 Apr 6 IS - 0042-4900 TA - Vet Rec PG - 316-9 SB - M CY - ENGLAND IP - 14 VI - 94 JC - XBS EM - 7409 PMID- 4832072 CU - 88 SO - Vet Rec 1974 Apr 6;94(14):316-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74292542 AU - Malakhov IuA TI - [Diagnosis of leptospirosis in bulls and boars] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/microbiology/*veterinary MH - Serotyping MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 741031 DP - 1974 Apr IS - 0042-4846 TA - Veterinariia PG - 59-61 CY - USSR IP - 4 VI - 50 JC - XCC EM - 7412 RO - O:46 RO - C:26 PMID- 4858935 CU - 85 TT - K diagnostike leptospiroza u bykov i khriakov SO - Veterinariia 1974 Apr;50(4):59-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 74175482 AU - Weidner DR TI - Leptospirosis--a review. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Carrier State/veterinary MH - Child MH - Demography MH - Diagnosis, Differential MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis/drug therapy/epidemiology/etiology/veterinary MH - Male MH - Middle Age MH - Occupational Diseases/etiology MH - Penicillins/therapeutic use MH - Seasons MH - Serodiagnosis MH - Serotyping MH - Tetracycline/therapeutic use MH - United States MH - Water Microbiology MH - Zoonoses PT - JOURNAL ARTICLE PT - REVIEW DA - 740730 DP - 1974 Apr IS - 0011-7781 TA - Del Med J PG - 181-8 CY - UNITED STATES IP - 4 VI - 46 JC - E0B EM - 7409 RF - 49 PMID- 4598744 CU - 90 SO - Del Med J 1974 Apr;46(4):181-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74263259 AU - Imamura S AU - Matsui H AU - Ashizawa Y TI - Indirect hemagglutination test for detection of leptospiral antibodies. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*analysis MH - Comparative Study MH - Cross Reactions MH - Erythrocytes/immunology MH - *Hemagglutination Tests MH - Human MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis/immunology MH - Rabbits/immunology MH - Sheep/immunology MH - Time Factors PT - JOURNAL ARTICLE DA - 740905 DP - 1974 Apr IS - 0021-5031 TA - Jpn J Exp Med PG - 191-7 SB - M CY - JAPAN IP - 2 VI - 44 JC - KJR EM - 7410 RO - O:32 RO - C:29 PMID- 4546074 CU - 90 SO - Jpn J Exp Med 1974 Apr;44(2):191-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 75010618 AU - Summers PM AU - Campbell RS AU - Dennett DP TI - Herd studies on the genital pathology of infertile beef cows. LA - Eng MH - Animal MH - Antibodies, Bacterial MH - Cattle MH - Cattle Diseases/epidemiology/etiology/immunology/microbiology/*pathology MH - Endometritis/epidemiology/veterinary MH - Female MH - Genitalia, Female/*pathology MH - Infertility, Female/etiology/immunology/microbiology/pathology/*veterinary MH - Leptospira/immunology MH - Ovarian Diseases/epidemiology/veterinary MH - Pregnancy MH - Salpingitis/epidemiology/veterinary PT - JOURNAL ARTICLE DA - 741210 DP - 1974 Apr IS - 0005-0423 TA - Aust Vet J PG - 150-4 SB - M CY - AUSTRALIA IP - 4 VI - 50 JC - 9IE EM - 7501 PMID- 4413668 CU - 88 SO - Aust Vet J 1974 Apr;50(4):150-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 75006271 AU - Faine S AU - Adler B AU - Ruta G TI - A mechanism of immunity to leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Antigens, Bacterial MH - Blood Bactericidal Activity MH - Carrier State/immunology MH - Guinea Pigs MH - Hemagglutination Tests MH - Immune Sera MH - Immunity, Active MH - Immunization MH - Immunization, Passive MH - Leptospira interrogans/*immunology MH - Leptospirosis/*immunology/prevention & control MH - Lipopolysaccharides MH - Mice MH - Opsonins MH - Phosphorus Radioisotopes MH - Rabbits PT - JOURNAL ARTICLE DA - 741210 DP - 1974 Apr IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 301-10 SB - M CY - AUSTRALIA IP - 2 VI - 52 JC - 9FW EM - 7501 PMID- 4411656 SO - Aust J Exp Biol Med Sci 1974 Apr;52(2):301-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 76035800 AU - Sauer H AU - Marklein G AU - Schafer E TI - [Evaluation of cross-reactions with hepatitis-B-antigen (Australia- antigen) in the Ausria-testsystem (author's transl)] LA - Ger MH - Antigens, Bacterial MH - Antigens, Viral MH - *Cross Reactions MH - Hepatitis B/diagnosis MH - Hepatitis B Antigens/*analysis MH - Human MH - Leptospira/immunology MH - Mycoplasma/immunology MH - Radioimmunoassay/*standards MH - Rickettsia/immunology PT - JOURNAL ARTICLE DA - 751220 DP - 1974 Apr IS - 0300-872X TA - Z Immunitatsforsch Exp Klin Immunol PG - 414-22 SB - M CY - GERMANY, WEST IP - 5 VI - 146 JC - XW2 EM - 7602 PMID- 4282990 CU - 92 TT - Zur Frage der Kreuzreaktionen mit Hepatitis-B-Antigen (Australia- Antigen) im Ausria-125-Testsystem SO - Z Immunitatsforsch Exp Klin Immunol 1974 Apr;146(5):414-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 75007943 AU - Faine S AU - Adler B AU - Palit A TI - Chemical, serological and biological properties of a serotype-specific polysaccharide antigen in Leptospira. LA - Eng MH - Animal MH - *Antigens, Bacterial/analysis/toxicity MH - Capillary Permeability MH - Chromatography, Gas MH - Chromatography, Paper MH - Cross Reactions MH - Female MH - Hemagglutination Inhibition Tests MH - Hemagglutination Tests MH - Immunodiffusion MH - Leptospira/*immunology MH - Leptospira interrogans/immunology MH - *Lipopolysaccharides/analysis/toxicity MH - Mice MH - Monosaccharides/analysis MH - Rabbits MH - Serotyping MH - Shwartzman Phenomenon MH - Skin/blood supply PT - JOURNAL ARTICLE DA - 741210 DP - 1974 Apr IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 311-9 SB - M CY - AUSTRALIA IP - 2 VI - 52 JC - 9FW EM - 7501 PMID- 4212990 CU - 91 SO - Aust J Exp Biol Med Sci 1974 Apr;52(2):311-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74174158 AU - Ellis WA AU - Michna SW TI - Experimental leptospiral abortion in cattle. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Antibodies, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*etiology MH - Female MH - Kidney/microbiology MH - Leptospirosis/complications/*veterinary MH - Lung/microbiology MH - Placenta/microbiology MH - Pregnancy PT - JOURNAL ARTICLE DA - 740726 DP - 1974 Mar 23 IS - 0042-4900 TA - Vet Rec PG - 255 SB - M CY - ENGLAND IP - 12 VI - 94 JC - XBS EM - 7409 PMID- 4831585 SO - Vet Rec 1974 Mar 23;94(12):255 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 74287822 AU - Stalheim OH TI - Effect of animal-passage and in vitro cultivation in homologous antiserum on leptospiral antigenicity. LA - Eng MH - Animal MH - *Antigens, Bacterial MH - Cattle MH - Comparative Study MH - Culture Media MH - Guinea Pigs MH - Hamsters MH - *Immune Sera MH - In Vitro MH - Leptospira/*immunology MH - Leptospirosis/*immunology/veterinary MH - Serotyping MH - Swine MH - Swine Diseases/immunology PT - JOURNAL ARTICLE DA - 741002 DP - 1974 Mar IS - 0003-9055 TA - Arch Exp Veterinarmed PG - 243-7 SB - M CY - GERMANY, EAST IP - 3 VI - 28 JC - 70I EM - 7411 PMID- 4846590 CU - 84 SO - Arch Exp Veterinarmed 1974 Mar;28(3):243-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 74252551 AU - Tan DS AU - Welch QB TI - Evaluation of Leptospira biflexa antigens for screening human sera by the microscopic agglutination (MA) test in comparison with the sensitized-erythrocyte-lysis (SEL) test. LA - Eng MH - *Agglutination Tests MH - *Antigens, Bacterial MH - Comparative Study MH - Erythrocytes/*immunology MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Malaysia MH - Methods MH - *Serodiagnosis PT - JOURNAL ARTICLE DA - 740822 DP - 1974 Mar IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 12-6 SB - M CY - THAILAND IP - 1 VI - 5 JC - UVN EM - 7410 RO - O:45 RO - C:00 PMID- 4839075 CU - 90 SO - Southeast Asian J Trop Med Public Health 1974 Mar;5(1):12-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 74171892 AU - Michna SW AU - Ellis W TI - The isolation of Leptospira belonging to the serogroup ballum from the kidneys of a brown rat (Rattus norvegicus). LA - Eng MH - Animal MH - Carrier State/microbiology/veterinary MH - Female MH - Kidney/*microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/veterinary MH - *Rats MH - Rodent Diseases/*microbiology MH - Serotyping PT - JOURNAL ARTICLE DA - 740725 DP - 1974 Mar IS - 0034-5288 TA - Res Vet Sci PG - 263-4 SB - M CY - ENGLAND IP - 2 VI - 16 JC - R7D EM - 7409 PMID- 4830988 SO - Res Vet Sci 1974 Mar;16(2):263-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 74151122 AU - Woods GT AU - Mansfield ME TI - Transplacental migration of swine influenza virus in gilts exposed experimentally. LA - Eng MH - Animal MH - Animals, Newborn MH - Female MH - Fetal Death MH - Fetal Diseases/microbiology MH - Influenza/microbiology/veterinary MH - Influenza Vaccine MH - Kidney/microbiology MH - Leptospira MH - Liver/microbiology MH - Lung/microbiology MH - *Maternal-Fetal Exchange MH - *Orthomyxoviridae/isolation & purification MH - Pregnancy MH - *Swine MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 740626 DP - 1974 Mar IS - 0034-5164 TA - Res Commun Chem Pathol Pharmacol PG - 629-32 SB - M CY - UNITED STATES IP - 3 VI - 7 JC - R62 EM - 7408 PMID- 4824834 SO - Res Commun Chem Pathol Pharmacol 1974 Mar;7(3):629-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 74109119 AU - Birnbaum S AU - Torten M AU - Shenberg E TI - Experimental evidence for a cyclic occurrence of leptospirosis in vector mice. LA - Eng MH - Animal MH - Antibodies MH - Carrier State/immunology/*veterinary MH - Disease Vectors MH - Female MH - Immunity, Maternally-Acquired MH - Leptospirosis/immunology/*veterinary MH - Maternal-Fetal Exchange MH - Mice MH - *Periodicity MH - Pregnancy MH - Rodent Diseases/*epidemiology/immunology PT - JOURNAL ARTICLE DA - 740429 DP - 1974 Mar IS - 0002-9262 TA - Am J Epidemiol PG - 225-9 SB - M CY - UNITED STATES IP - 3 VI - 99 JC - 3H3 EM - 7406 PMID- 4814692 CU - 88 SO - Am J Epidemiol 1974 Mar;99(3):225-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [4 medline neighbors] UI - 74252329 AU - Mesina JE AU - Campbell RS AU - Glazebrook JS AU - Copeman DB AU - Johnson RH TI - The pathology of feral rodents in North Queensland. LA - Eng MH - Animal MH - Australia MH - Dysentery, Bacillary/pathology/veterinary MH - Hepatitis A/pathology/veterinary MH - Leptospirosis/pathology/veterinary MH - Liver Diseases, Parasitic/pathology/veterinary MH - Mice MH - Myocarditis/pathology/veterinary MH - Nematode Infections/pathology/veterinary MH - Nephritis, Interstitial/pathology/veterinary MH - Pneumonia/pathology/veterinary MH - Pseudomonas Infections/pathology/veterinary MH - Pulmonary Fibrosis/pathology/veterinary MH - Rats MH - Rodent Diseases/*pathology MH - Rodentia MH - Salmonella typhimurium MH - Salmonella Infections, Animal/pathology MH - Shigella dysenteriae PT - JOURNAL ARTICLE DA - 740823 DP - 1974 Mar TA - Tropenmed Parasitol PG - 116-27 SB - M CY - GERMANY, WEST IP - 1 VI - 25 JC - WGM EM - 7410 RO - O:44 RO - C:22 PMID- 4599296 CU - 90 SO - Tropenmed Parasitol 1974 Mar;25(1):116-27 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 74133710 AU - Glorioso JC AU - Amborski RL AU - Larkin JM AU - Amborski GF AU - Culley DC TI - Laboratory identification of bacterial pathogens of aquatic animals. LA - Eng MH - *Amphibia MH - Animal MH - Anura MH - Bacteria/classification/*isolation & purification MH - Bacteriological Techniques MH - Cell Movement MH - *Fishes MH - Leptospira/isolation & purification MH - Rana catesbeiana MH - *Reptiles MH - Streptomyces/isolation & purification MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 740601 DP - 1974 Mar IS - 0002-9645 TA - Am J Vet Res PG - 447-50 SB - M CY - UNITED STATES IP - 3 VI - 35 JC - 40C EM - 7407 PMID- 4594746 CU - 90 SO - Am J Vet Res 1974 Mar;35(3):447-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 74257698 AU - Hodges RT AU - Ris DR TI - Complement fixing and agglutinating antibody responses and Leptospiruria in calves inoculated with leptospira serotypes pomona, hardjo, copenhageni or ballum. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/*biosynthesis MH - Bacteriuria/immunology/*veterinary MH - Cattle MH - Cattle Diseases/*immunology MH - Complement Fixation Tests MH - Female MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Serotyping MH - Species Specificity PT - JOURNAL ARTICLE DA - 740823 DP - 1974 Mar IS - 0048-0169 TA - N Z Vet J PG - 25-30 CY - NEW ZEALAND IP - 3 VI - 22 JC - OBZ EM - 7410 RO - O:45 RO - C:00 PMID- 4525263 CU - 88 SO - N Z Vet J 1974 Mar;22(3):25-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 74257697 AU - Hodges RT TI - The use of a polyvalent antigen in complement fixation tests for bovine leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - *Antigens, Bacterial MH - Cattle MH - Cattle Diseases/*diagnosis/immunology MH - Complement Fixation Tests MH - Leptospira/*immunology MH - Leptospirosis/diagnosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 740823 DP - 1974 Mar IS - 0048-0169 TA - N Z Vet J PG - 21-4 CY - NEW ZEALAND IP - 3 VI - 22 JC - OBZ EM - 7410 RO - O:45 RO - C:00 PMID- 4525262 CU - 88 SO - N Z Vet J 1974 Mar;22(3):21-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 75063238 AU - Mizon JP AU - Laude M AU - Laurans J AU - Gentit F AU - Lienard J TI - [Leptospira icterohemorrhagiae. Clinical and bacteriologic study. (Apropos of 3 cases)] LA - Fre MH - Adult MH - France MH - Human MH - Leptospira interrogans/*isolation & purification MH - Male MH - Weil's Disease/epidemiology/*microbiology PT - JOURNAL ARTICLE DA - 750310 DP - 1974 Mar IS - 0024-3507 TA - Lille Med PG - 293-301 CY - FRANCE IP - 3 VI - 19 JC - L6W EM - 7504 PMID- 4437280 CU - 88 TT - La leptospirose ictero hemorragique. Etude clinique et bacteriologique (a propos de 3 observations) SO - Lille Med 1974 Mar;19(3):293-301 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [101 medline neighbors] UI - 75170638 AU - Ruban EL TI - [Bacterial lipids] LA - Rus MH - Azotobacteraceae/chemistry MH - Bacillus subtilis/chemistry MH - Bacteria/*chemistry MH - Bacteroides/chemistry MH - Cardiolipins/analysis MH - Cell Membrane/chemistry MH - Clostridium/chemistry MH - Corynebacterium diphtheriae/chemistry MH - Culture Media MH - English Abstract MH - Escherichia coli/chemistry MH - Fatty Acids/analysis MH - Fatty Acids, Unsaturated/analysis MH - Glycolipids/analysis MH - Hydrogen-Ion Concentration MH - L Forms/chemistry MH - Leptospira/chemistry MH - Lipids/*analysis MH - Lipopolysaccharides/analysis MH - Mycobacterium/chemistry MH - Paracoccus denitrificans/chemistry MH - Phospholipids/analysis MH - Polysaccharides, Bacterial/analysis MH - Proteus vulgaris/chemistry MH - Pseudomonas aeruginosa/chemistry MH - Salmonella typhimurium/chemistry MH - Serratia marcescens/chemistry MH - Staphylococcus/chemistry MH - Streptococcus pneumoniae/chemistry MH - Streptococcus pyogenes/chemistry MH - Temperature MH - Vibrio cholerae/*chemistry PT - JOURNAL ARTICLE PT - REVIEW DA - 750820 DP - 1974 Mar-Apr IS - 0002-3329 TA - Izv Akad Nauk SSSR Biol PG - 162-78 CY - RUSSIA IP - 2 JC - H0D EM - 7510 RF - 120 RO - M:MSH RO - M:NES PMID- 4156687 LR - 940616 CU - 94 TT - Bakterial'nye lipidy EA - A SO - Izv Akad Nauk SSSR Biol 1974 Mar-Apr;(2):162-78 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 74091585 AU - Barkin RM AU - Guckian JC AU - Glosser JW TI - Infection by leptospira ballum: a laboratory-associated case. LA - Eng MH - Adult MH - Animal MH - Bites and Stings/complications MH - Disease Vectors MH - Dogs MH - Human MH - Laboratory Infection/*etiology MH - Leptospira/*isolation & purification MH - Leptospirosis/*etiology MH - Male MH - *Mice PT - JOURNAL ARTICLE DA - 740402 DP - 1974 Feb IS - 0038-4348 TA - South Med J PG - 155 passim SB - M CY - UNITED STATES IP - 2 VI - 67 JC - UVH EM - 7405 PMID- 4855805 CU - 85 SO - South Med J 1974 Feb;67(2):155 passim ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 75124854 AU - Abramson LA AU - Malafeeva LS AU - Kartseva TS AU - Drankin DI TI - [Leptosiral infections among dogs in Saratov] LA - Rus MH - Animal MH - Antibodies, Bacterial MH - Dog Diseases/*epidemiology MH - Dogs MH - Leptospira/immunology MH - Leptospira canicola MH - Leptospirosis/epidemiology/*veterinary MH - Weil's Disease/veterinary PT - JOURNAL ARTICLE DA - 750527 DP - 1974 Feb IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 152-3 SB - M CY - RUSSIA IP - 2 JC - Y9O EM - 7507 RO - M:NES PMID- 4454852 LR - 940617 CU - 89 TT - Infitsirovannost' leptospirami sobak v Saratove SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Feb;(2):152-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 75124847 AU - Shliakhov EN AU - Gazhim SP AU - Kovaliu SV TI - [A method of drawing a sectoral-polar diagram] LA - Rus MH - Comparative Study MH - Epidemiologic Methods MH - Human MH - Leptospirosis/epidemiology MH - Mathematics MH - Seasons PT - JOURNAL ARTICLE DA - 750527 DP - 1974 Feb TA - Zh Mikrobiol Epidemiol Immunobiol PG - 144-7 SB - M CY - USSR IP - 2 JC - Y9O EM - 7507 PMID- 4454849 CU - 89 TT - Metodika postroeniia sektorno-poliarnoi diagrammy SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Feb;(2):144-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 74278944 AU - Kiktenko WS AU - Bakulina NA AU - Lewina LF TI - [Ring-shaped structures in Leptospirae (author's transl)] LA - Ger MH - Antibodies MH - Culture Media MH - English Abstract MH - Formaldehyde/pharmacology MH - Heat MH - Leptospira/*cytology/drug effects MH - Microscopy, Electron MH - *Organoids MH - Physical Stimulation MH - Protoplasts MH - Stimulation, Chemical MH - Ultrasonics PT - JOURNAL ARTICLE DA - 741009 DP - 1974 Feb IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 91-6 SB - M CY - GERMANY, WEST IP - 1 VI - 226 JC - Y52 EM - 7411 RO - O:44 RO - C:22 PMID- 4152344 CU - 94 TT - Ringformige Gebilde bei Leptospiren EA - A SO - Zentralbl Bakteriol [Orig A] 1974 Feb;226(1):91-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 74144312 AU - Ackermann HW AU - Cherchel G AU - Valet JP AU - Matte J AU - Moorjani S AU - Higgins R TI - [Characterization of particles found in clinical cases of viral hepatitis: coronavirus-like particles, Australia antigen and Dane particles] LA - Fre MH - Adult MH - Agglutination Tests MH - Animal MH - Centrifugation, Density Gradient MH - Coronaviridae/analysis/*isolation & purification MH - English Abstract MH - Guinea Pigs MH - Hepatitis A/*blood MH - Hepatitis B Antigens/analysis/*isolation & purification MH - Human MH - Immunodiffusion MH - *Inclusion Bodies, Viral MH - Leptospira interrogans MH - Leptospirosis/blood MH - Lipoproteins/analysis MH - Male MH - Microscopy, Electron MH - Nucleic Acids/analysis MH - Nucleoproteins/analysis MH - Phosphoproteins/analysis MH - Staining MH - Viral Proteins/analysis PT - JOURNAL ARTICLE DA - 740614 DP - 1974 Feb IS - 0008-4166 TA - Can J Microbiol PG - 193-203 SB - M CY - CANADA IP - 2 VI - 20 JC - CJ3 EM - 7408 PMID- 4132609 CU - 95 TT - Experiences sur la nature de particules trouvees dans des cas d'hepatite virale: type coronavirus, antigene Australia et particules de Dane. SO - Can J Microbiol 1974 Feb;20(2):193-203 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 74283414 AU - Pinto AA AU - Rosa CA AU - Sadatsune T AU - Fleury GC TI - Comparative study between complement fixation and microscopic agglutination tests for leptospiral diagnosis. LA - Eng MH - *Agglutination Tests MH - Animal MH - Comparative Study MH - *Complement Fixation Tests MH - Dog Diseases/*diagnosis MH - Dogs MH - Evaluation Studies MH - Horse Diseases/*diagnosis MH - Horses MH - Human MH - Leptospirosis/*diagnosis/veterinary MH - Microscopy MH - Perissodactyla PT - JOURNAL ARTICLE DA - 740930 DP - 1974 Jan IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 28-31 CY - BRAZIL IP - 1 VI - 16 JC - S9D EM - 7411 RO - O:23 RO - C:01 PMID- 4858599 CU - 85 SO - Rev Inst Med Trop Sao Paulo 1974 Jan;16(1):28-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 74253679 AU - Sebek Z TI - Results of serologic examination of domestic animals for leptospirosis in the Mongolian People's Republic. LA - Eng MH - Agglutination Tests MH - Animal MH - *Animals, Domestic MH - Camels MH - Cattle MH - Cattle Diseases/immunology MH - Goats MH - Horse Diseases/immunology MH - Horses MH - Leptospirosis/epidemiology/etiology/immunology/*veterinary MH - Mongolia MH - Sheep MH - Sheep Diseases/immunology PT - JOURNAL ARTICLE DA - 740821 DP - 1974 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 21-8 CY - CZECHOSLOVAKIA IP - 1 VI - 21 JC - F2T EM - 7410 RO - O:45 RO - C:29 PMID- 4857752 CU - 88 SO - Folia Parasitol (Praha) 1974;21(1):21-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [73 medline neighbors] UI - 74081529 AU - Smith AW AU - Prato CM AU - Gilmartin WG AU - Brown RJ AU - Keyes MC TI - A preliminary report on potentially pathogenic microbiological agents recently isolated from pinnipeds. LA - Eng MH - Animal MH - Female MH - Guinea Pigs MH - Hamsters MH - Hyphomycetes/isolation & purification MH - Infection/*veterinary MH - Leptospira/isolation & purification/pathogenicity MH - Leptospirosis/microbiology/veterinary MH - Male MH - Mice MH - Mycoplasma/isolation & purification MH - Mycoplasma Infections/microbiology/veterinary MH - Mycoses/microbiology/veterinary MH - Picornaviridae/isolation & purification/pathogenicity MH - *Pinnipedia MH - Swine MH - Vesicular Exanthema of Swine/microbiology MH - Virus Diseases/microbiology/veterinary PT - JOURNAL ARTICLE DA - 740318 DP - 1974 Jan IS - 0090-3558 TA - J Wildl Dis PG - 54-9 SB - M CY - UNITED STATES IP - 1 VI - 10 JC - KEM EM - 7405 PMID- 4855675 CU - 85 SO - J Wildl Dis 1974 Jan;10(1):54-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74288742 AU - Dvornik J AU - Vachtenheim J TI - [Inflammatory joint syndrome as the main clinical manifestation of leptospirosis] LA - Cze MH - Adult MH - English Abstract MH - Human MH - Inflammation MH - Joint Diseases/diagnosis/*etiology MH - *Leptospirosis/diagnosis MH - Male MH - Syndrome PT - JOURNAL ARTICLE DA - 741002 DP - 1974 Jan IS - 0042-773X TA - Vnitr Lek PG - 78-81 CY - CZECHOSLOVAKIA IP - 1 VI - 20 JC - XFY EM - 7411 PMID- 4847021 CU - 90 TT - Zanetlivy kloubni syndrom jako hlavni klinicky projev leptospirozy. SO - Vnitr Lek 1974 Jan;20(1):78-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 74253677 AU - Rosicky B AU - Sebek Z TI - To the evolution of natural foci of L. grippotyphosa in Central Europe. LA - Eng MH - Agglutination Tests MH - Animal MH - Carnivora MH - Czechoslovakia MH - Disease Reservoirs MH - Europe MH - Foxes MH - Insectivora MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Rodent Diseases/epidemiology/immunology MH - Rodentia MH - Sciuridae PT - JOURNAL ARTICLE DA - 740821 DP - 1974 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 11-20 CY - CZECHOSLOVAKIA IP - 1 VI - 21 JC - F2T EM - 7410 RO - O:45 RO - C:29 PMID- 4836171 CU - 88 SO - Folia Parasitol (Praha) 1974;21(1):11-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 74061327 AU - Charon NW AU - Johnson RC AU - Peterson D TI - Amino acid biosynthesis in the spirochete Leptospira: evidence for a novel pathway of isoleucine biosynthesis. LA - Eng MH - Amino Acids/*biosynthesis/metabolism MH - Aspartic Acid/metabolism MH - Bicarbonates/metabolism MH - Carbon Dioxide/metabolism MH - Carbon Radioisotopes MH - Cell Fractionation MH - Culture Media MH - Glutamates/metabolism MH - Glycine/metabolism MH - Isoleucine/*biosynthesis MH - Leptospira/growth & development/*metabolism MH - Palmitic Acids/metabolism MH - Pyruvates/metabolism MH - Serotyping MH - Stereoisomerism MH - Threonine/metabolism MH - Toluene/metabolism PT - JOURNAL ARTICLE DA - 740222 DP - 1974 Jan IS - 0021-9193 TA - J Bacteriol PG - 203-11 SB - M CY - UNITED STATES IP - 1 VI - 117 JC - HH3 EM - 7404 PMID- 4808901 CU - 96 SO - J Bacteriol 1974 Jan;117(1):203-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 75034883 AU - Ioli A AU - Munao F AU - Cananzi F TI - [Results of comparative studies of some tests for characterization of Leptospira (8-azaguanine, egg's red, oxidases and cationic detergent test)] LA - Ita MH - *Azaguanine MH - Bacteriological Techniques/*methods MH - Comparative Study MH - *Detergents MH - Egg Yolk MH - English Abstract MH - Female MH - Leptospira/classification/*isolation & purification MH - Oxidoreductases PT - JOURNAL ARTICLE DA - 750113 DP - 1974 Jan-Feb IS - 0003-472X TA - Ann Sclavo PG - 87-90 CY - ITALY IP - 1 VI - 16 JC - 65C EM - 7502 PMID- 4609309 CU - 90 TT - Risultati di prove comparative tra alcuni tests per la caratterizzazione delle Leptospire (test all'8-azaguanina, al rosso d'uovo, all'ossidasi, al detergente cationico) EA - A SO - Ann Sclavo 1974 Jan-Feb;16(1):87-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [67 medline neighbors] UI - 74302773 AU - Pinheiro FP AU - Bensabath G AU - Andrade AH AU - Lins ZC AU - Fraiha H AU - Tang AT AU - Lainson R AU - Shaw JJ AU - Azevedo MC TI - Infectious diseases along Brazil's trans-amazon highway: surveillance and research. LA - Eng MH - Animal MH - Antibodies, Viral/analysis MH - Arbovirus Infections/*epidemiology/immunology MH - Arboviruses/immunology/isolation & purification MH - Brazil MH - Disease Reservoirs/veterinary MH - Disease Vectors MH - Enterobacteriaceae Infections/*epidemiology/microbiology MH - Hemagglutination Inhibition Tests MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology/microbiology MH - Neutralization Tests MH - Parasitic Diseases/*epidemiology MH - Purpura, Thrombocytopenic/blood/*epidemiology MH - Residence Characteristics MH - Salmonella/isolation & purification MH - Schistosomiasis/epidemiology MH - Shigella dysenteriae/isolation & purification MH - Syndrome PT - JOURNAL ARTICLE DA - 741116 DP - 1974 TA - Bull Pan Am Health Organ PG - 111-22 CY - UNITED STATES IP - 2 VI - 8 JC - BSB EM - 7412 RO - O:45 RO - C:00 PMID- 4604602 CU - 90 SO - Bull Pan Am Health Organ 1974;8(2):111-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 74076708 AU - Ris DR TI - Limitations of the use of 5-fluorouracil as a selective agent for the isolation of leptospirae. LA - Eng MH - Aerobiosis MH - Animal MH - Bacteria/growth & development MH - Bacteriological Techniques MH - Cattle MH - Comparative Study MH - *Culture Media MH - Drug Resistance, Microbial MH - Escherichia/growth & development MH - Fluorouracil/*pharmacology MH - Immune Sera MH - Leptospira/drug effects/growth & development/*isolation & purification MH - Meat MH - Micrococcus/growth & development MH - Peptones MH - Sheep/immunology MH - Staphylococcus/growth & development MH - Temperature MH - Tissue Extracts PT - JOURNAL ARTICLE DA - 740308 DP - 1974 Jan IS - 0003-6919 TA - Appl Microbiol PG - 270-1 SB - M CY - UNITED STATES IP - 1 VI - 27 JC - 6K0 EM - 7404 PMID- 4589135 CU - 90 SO - Appl Microbiol 1974 Jan;27(1):270-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 77102944 AU - Strother HL TI - Host animal efficacy studies using a multivalent leptospira bacterin LA - Eng MH - Animal MH - Bacterial Vaccines/*standards MH - Cattle MH - Cattle Diseases/*prevention & control MH - Leptospira/*immunology MH - Leptospirosis/prevention & control/*veterinary MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 770315 DP - 1974 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 131-5 CY - UNITED STATES IP - 78 JC - PY5 EM - 7705 PMID- 4534750 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1974;(78):131-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 77102942 AU - Glosser JW AU - Sulzer CR AU - Reynolds GC AU - Whitsett DK TI - Isolation of leptospiral serotype szwajizak from dairy cattle in Oregon. LA - Eng MH - Abortion, Veterinary/microbiology MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Oregon MH - Pregnancy PT - JOURNAL ARTICLE DA - 770315 DP - 1974 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 119-25 CY - UNITED STATES IP - 78 JC - PY5 EM - 7705 PMID- 4534749 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1974;(78):119-25 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 75124760 AU - Kiktenko VS AU - Bakulina NA AU - Levina LF TI - [An electron microscopic study of the ultrastructure of leptospirae and their formation of agglutinates] LA - Rus MH - *Agglutination MH - Animal MH - Complement MH - English Abstract MH - Leptospira interrogans/immunology/*ultrastructure MH - Membranes/immunology MH - Microscopy, Electron MH - Rabbits/immunology MH - Time Factors PT - JOURNAL ARTICLE DA - 750527 DP - 1974 Jan TA - Zh Mikrobiol Epidemiol Immunobiol PG - 71-6 SB - M CY - USSR IP - 1 JC - Y9O EM - 7507 PMID- 4476968 CU - 90 TT - Elektronnomikroskopicheskoe issledovanie ul'trastruktury leptospir i formirovaniia ikh aggliutinatov EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1974 Jan;(1):71-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 75086862 AU - Stoianova L AU - Todorova R TI - [Attempt to establish evaluation standards for a bivalent vaccine against leptospirosis of farm animals, using LMAR (leptospirosis micro- agglutination reaction] LA - Bul MH - *Agglutination Tests MH - Animal MH - Bacterial Vaccines/*standards MH - Leptospira/immunology MH - Leptospirosis/immunology/*veterinary MH - Rabbits MH - Rodent Diseases/immunology MH - Sheep MH - Sheep Diseases/immunology MH - Swine MH - Swine Diseases/immunology MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 750423 DP - 1974 TA - Vet Med Nauki PG - 39-45 SB - M CY - BULGARIA IP - 7 VI - 11 JC - XCE EM - 7505 PMID- 4475510 CU - 89 TT - Opiti za ustanoviavane normi za pretsenka na bivalentna vaksina sreshtu leptospiroza po selskostopanskite zhivotni chrez RMAL SO - Vet Med Nauki 1974;11(7):39-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 76251135 AU - Silva I AU - Bocciarelli DS AU - Valente FR AU - Crateri PT TI - Electron microscope identification of mesosomes in some water strains of Leptospira by reduction of tetrazolium chloride to formazans. LA - Eng MH - English Abstract MH - Formazans/biosynthesis MH - Leptospira/metabolism/*ultrastructure MH - Tetrazolium Salts/metabolism PT - JOURNAL ARTICLE DA - 760925 DP - 1974 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 179-82 SB - M CY - ITALY IP - 3-4 VI - 10 JC - 5BP AA - Author EM - 7611 AB - Rounded granules protruding from the external surface of some water Leptospira strains and considered as mesosomes were studied by electron microscope and by means of the intravital reduction of tetrazolium chloride. Satisfactory results were obtained with two of the strains studied. It appears that neither the culture medium nor the age of the culture have any influence on the unusual position of the mesosomes. PMID- 4470987 CU - 90 EA - A SO - Ann Ist Super Sanita 1974;10(3-4):179-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 76017934 AU - Santa Rosa CA AU - Pinto AA TI - [The diagnosis of animal leptospirosis by the complement fixation test (author's transl)] LA - Por MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial MH - Comparative Study MH - *Complement Fixation Tests MH - Dog Diseases/*diagnosis MH - Dogs MH - English Abstract MH - Horse Diseases/*diagnosis MH - Horses MH - Leptospirosis/diagnosis/*veterinary MH - Perissodactyla PT - JOURNAL ARTICLE DA - 751122 DP - 1974 Jan-Mar IS - 0020-3653 TA - Arq Inst Biol (Sao Paulo) PG - 19-23 SB - M CY - BRAZIL IP - 1 VI - 41 JC - 8VF EM - 7601 PMID- 4466483 TT - Reacao de fixacao do complemento no diagnostico de leptospirose animal. Emprego de um antigeno de amostra apatogenica EA - A SO - Arq Inst Biol (Sao Paulo) 1974 Jan-Mar;41(1):19-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 76017781 AU - Stalheim OH TI - Effect of animal-passage and in vitro cultivation in homologous antiserum on leptospiral antigenicity. LA - Eng MH - Animal MH - Antigens MH - Cattle/immunology MH - *Culture Media MH - Hamsters/immunology MH - Immune Sera MH - Leptospira/*immunology MH - Swine/immunology MH - Virulence PT - JOURNAL ARTICLE DA - 751122 DP - 1974 IS - 0003-9055 TA - Arch Exp Veterinarmed PG - 243-7 SB - M CY - GERMANY, EAST IP - 2 VI - 28 JC - 70I EM - 7601 PMID- 4466479 CU - 84 SO - Arch Exp Veterinarmed 1974;28(2):243-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 76017148 AU - Silva I TI - [Systematic study of saprophytic leptospirae isolated in Brazil] LA - Ita MH - Brazil MH - English Abstract MH - Leptospira/*classification MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 751122 DP - 1974 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 21-5 SB - M CY - ITALY IP - 1-2 VI - 10 JC - 5BP EM - 7601 PMID- 4466398 TT - Studio sistematico di leptospire saprofite isolate in Brasile EA - A SO - Ann Ist Super Sanita 1974;10(1-2):21-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 76014019 AU - Lettow E TI - [Liver diseases in the dog 2. A review from the clinical standpoint] LA - Ger MH - Animal MH - Chronic Disease MH - Dog Diseases/*diagnosis MH - Dogs MH - Fatty Liver/diagnosis/veterinary MH - Female MH - Hepatitis, Infectious Canine/diagnosis MH - Hepatomegaly/diagnosis/veterinary MH - Leptospirosis/diagnosis/veterinary MH - Liver Cirrhosis/diagnosis/veterinary MH - Liver Diseases/diagnosis/*veterinary MH - Liver Neoplasms/diagnosis/veterinary MH - Lymphatic Diseases/diagnosis/veterinary MH - Male MH - Neoplasm Metastasis PT - JOURNAL ARTICLE DA - 751120 DP - 1974 IS - 0303-6286 TA - Tierarztl Prax PG - 419-33 SB - M CY - GERMANY, WEST IP - 4 VI - 2 JC - VS4 EM - 7601 RO - M:BDS PMID- 4465978 LR - 850301 TT - Lebererkrankungen beim Hund (2). Ein Uberblick aus klinischer Sicht SO - Tierarztl Prax 1974;2(4):419-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 75181575 AU - Babudieri B AU - Fraga de Azevedo J AU - Palmeiro JM TI - [Occurrence of the Leptospira arboreae serotype in Portugal] LA - Por MH - Animal MH - Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira/immunology MH - Portugal MH - Rodent Diseases/*epidemiology MH - Serotyping MH - Weil's Disease/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 750904 DP - 1974 Jan-Dec TA - An Inst Hig Med Trop (Lisb) PG - 471-7 CY - PORTUGAL IP - 1-4 VI - 2 JC - 4DL EM - 7510 PMID- 4462396 CU - 89 TT - A ocorrencia do sorotipo Leptospira arboreae em portugal EA - A SO - An Inst Hig Med Trop (Lisb) 1974 Jan-Dec;2(1-4):471-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 75180339 AU - Hergt R TI - [The occurrence of leptospirosis bratislava in the GDR] LA - Ger MH - Adult MH - English Abstract MH - Female MH - Germany, West MH - Human MH - Leptospirosis/*epidemiology MH - Middle Age PT - JOURNAL ARTICLE DA - 750905 DP - 1974 IS - 0049-8610 TA - Z Gesamte Hyg PG - 495-7 CY - GERMANY, EAST IP - 8 VI - 20 JC - XUO EM - 7510 PMID- 4462315 CU - 88 TT - Zum Vorkommen der Leptospirosis bratislava in der DDR EA - A SO - Z Gesamte Hyg 1974;20(8):495-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 75148312 AU - Mossop RT TI - A case report. Leptospirosis. LA - Eng MH - Adult MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Seasons MH - Zimbabwe PT - JOURNAL ARTICLE DA - 750731 DP - 1974 Jan IS - 0008-9176 TA - Cent Afr J Med PG - 12-4 CY - ZIMBABWE IP - 1 VI - 20 JC - CQO EM - 7509 PMID- 4458953 CU - 88 SO - Cent Afr J Med 1974 Jan;20(1):12-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 75143150 AU - Kazarian AS TI - [Serological indicators in rabbits in relation to brucellosis antigen] LA - Rus MH - Agglutination Tests MH - Agglutinins/isolation & purification MH - Animal MH - Antibody Formation MH - Antigens, Bacterial/*isolation & purification MH - Bacterial Vaccines/immunology MH - Brucella Vaccine/immunology MH - Brucellosis/*immunology MH - Leptospirosis/immunology MH - Pasteurella Infections/immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 750626 DP - 1974 TA - Zh Eksp Klin Med PG - 8-14 CY - USSR IP - 6 VI - 14 JC - Y9J EM - 7508 PMID- 4456935 CU - 89 TT - Serologicheskie pokazateli u krolikov v ostnoshenii brutselloznogo antitela SO - Zh Eksp Klin Med 1974;14(6):8-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 75099989 AU - Miller NG AU - Allen JE AU - Wilson RB TI - The pathogenesis of hemorrhage in the lung of the hamster during acute leptospirosis. LA - Eng MH - Acute Disease MH - Animal MH - Blood/microbiology MH - Capillaries/pathology MH - Hamsters MH - Hemoptysis/*etiology/pathology MH - Liver/microbiology MH - Lung/microbiology/*pathology MH - Microscopy, Electron MH - Pulmonary Alveoli/pathology MH - Weil's Disease/blood/*pathology PT - JOURNAL ARTICLE DA - 750504 DP - 1974 IS - 0300-8584 TA - Med Microbiol Immunol (Berl) PG - 269-78 SB - M CY - GERMANY, WEST IP - 4 VI - 160 JC - M58 EM - 7506 PMID- 4449515 SO - Med Microbiol Immunol (Berl) 1974;160(4):269-78 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 75088461 AU - Horenstein S TI - Miscellaneous forms of meningitis. LA - Eng MH - Amebiasis/complications MH - Brain Neoplasms/complications MH - Cysticercosis/complications MH - Encephalomyelitis/etiology MH - Filariasis/complications MH - Human MH - Leptospirosis/complications MH - Malaria/complications MH - *Meningitis/diagnosis/etiology MH - Meningoencephalitis/etiology MH - Nematode Infections/complications MH - Neoplasm Metastasis MH - Neurosyphilis/diagnosis/therapy MH - Optic Atrophy/etiology MH - Paragonimiasis/complications MH - Tuberculosis, Meningeal/diagnosis/therapy PT - JOURNAL ARTICLE DA - 750419 DP - 1974 IS - 0091-3952 TA - Adv Neurol PG - 205-21 SB - M CY - UNITED STATES VI - 6 JC - 2NX EM - 7505 PMID- 4447062 SO - Adv Neurol 1974;6:205-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 75084700 AU - Konarska D TI - [Survey of rodents and domestic animals in a focus of epidemic leptospirosis in the Wroclaw Province in 1971] LA - Pol MH - Animal MH - Animals, Domestic/*immunology MH - Antibodies, Bacterial/*analysis MH - Disease Outbreaks/*epidemiology MH - English Abstract MH - Leptospira/immunology MH - Leptospirosis/*epidemiology/veterinary MH - Poland MH - Rodentia/*immunology MH - Zoonoses PT - JOURNAL ARTICLE DA - 750411 DP - 1974 IS - 0033-2100 TA - Przegl Epidemiol PG - 535-42 CY - POLAND IP - 4 VI - 28 JC - Q8T EM - 7505 PMID- 4445526 CU - 88 TT - Badanie gryzoni i zwierzat domowych w ognisku epidemii leptospirozy w woj. wroclawskim w 1971 roku EA - A SO - Przegl Epidemiol 1974;28(4):535-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 75032298 AU - Mazzonelli J AU - Dorta de Mazzonelli G AU - Mailloux M TI - [Thermoresistant antigen in Leptospira (author's transl)] LA - Fre MH - *Antigens, Bacterial MH - English Abstract MH - Heat MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 750110 DP - 1974 Jan IS - 0300-5410 TA - Ann Microbiol (Paris) PG - 125-6 CY - FRANCE IP - 1 VI - 125A JC - 5JY EM - 7502 PMID- 4423875 TT - Antigene thermoresistant chez les leptospires EA - A SO - Ann Microbiol (Paris) 1974 Jan;125A(1):125-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [27 medline neighbors] UI - 75124940 AU - Mateev D AU - Kebedzhiev G AU - Manev Kh TI - [Distribution of leptospirosis in Bulgaria] LA - Rus MH - Adolescence MH - Adult MH - Age Factors MH - Agricultural Workers' Diseases/epidemiology MH - Animal MH - Bulgaria MH - Cattle MH - Cattle Diseases/epidemiology MH - Child MH - Comparative Study MH - English Abstract MH - Female MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - Leptospira/isolation & purification MH - Leptospira canicola MH - Leptospirosis/*epidemiology/etiology/veterinary MH - Male MH - Mice/microbiology MH - Occupations MH - Rats/microbiology MH - Rural Population MH - Seasons MH - Serotyping MH - Sex Factors MH - Swine MH - Swine Diseases/epidemiology MH - Time Factors MH - Urban Population MH - Water Microbiology MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 750527 DP - 1974 IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 22-8 SB - M CY - RUSSIA IP - 5 VI - 00 JC - Y9O EM - 7507 RO - M:NES PMID- 4378426 LR - 940617 CU - 90 TT - Rasprostranenie leptospirozov v Bolgarii EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1974;00(5):22-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 75124944 AU - Karaseva EV AU - Zaitsev SV AU - Chernukha IuG AU - Piskunova LA TI - [The ecology of pathogenic leptospirae under conditions of a natural focus] LA - Rus MH - Adaptation, Biological MH - Ecology MH - English Abstract MH - Humidity MH - Hydrogen-Ion Concentration MH - Leptospira/*physiology MH - Russia MH - Soil Microbiology MH - Time Factors MH - USSR PT - JOURNAL ARTICLE DA - 750527 DP - 1974 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 36-40 SB - M CY - USSR IP - 5 VI - 00 JC - Y9O EM - 7507 PMID- 4281605 CU - 92 TT - Nekotorye osobennosti ekologii patogennykh leptospir v estesvennykh usloviiakh prirodnogo ochaga EA - A SO - Zh Mikrobiol Epidemiol Immunobiol 1974;00(5):36-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 75092155 AU - Sebek Z AU - Rosicky B TI - [On the occurrence, characteristic and structure of the focci of leptospirosis in Czechoslovakia (author's transl)] LA - Cze MH - Antibody Formation MH - Czechoslovakia MH - Disease Reservoirs MH - English Abstract MH - Human MH - Leptospira/classification MH - Leptospirosis/*epidemiology/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 750517 DP - 1974 Jan IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 10-21 CY - CZECHOSLOVAKIA IP - 1 VI - 23 JC - CSH EM - 7506 PMID- 4280935 CU - 92 TT - K rozsireni, charakteristice a strukture ohnisek leptospirozy v CSSR EA - A SO - Cesk Epidemiol Mikrobiol Imunol 1974 Jan;23(1):10-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 74096245 AU - Stalheim OH TI - Urinary precipitate in porcine leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Erythrocytes/immunology MH - Glycosaminoglycans/urine MH - Hemolysis MH - Kidney Diseases/immunology/urine/veterinary MH - Leptospira/immunology MH - Leptospirosis/immunology/urine/*veterinary MH - Rabbits/immunology MH - Sheep/immunology MH - Swine MH - Swine Diseases/immunology/*urine PT - JOURNAL ARTICLE DA - 740404 DP - 1974 Jan IS - 0010-8901 TA - Cornell Vet PG - 20-4 SB - M CY - UNITED STATES IP - 1 VI - 64 JC - DRI EM - 7405 PMID- 4273051 CU - 92 SO - Cornell Vet 1974 Jan;64(1):20-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75105272 AU - Mailloux M AU - Mazzonelli J AU - Dorta de Mazzonelli GT TI - Thermoresistant antigen in leptospires. Possibility of a macroscopic diagnosis of leptospirosis with a single antigen. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - *Antigens, Bacterial MH - Heat MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/microbiology MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 750503 DP - 1974 IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 238-41 SB - M CY - GERMANY, WEST IP - 2 VI - 229 JC - Y52 EM - 7506 PMID- 4155869 CU - 94 SO - Zentralbl Bakteriol [Orig A] 1974;229(2):238-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 75105259 AU - Chernukcha YG AU - Ananyina YV AU - Zenkovitch NS TI - Pathogenicity of Leptospires of various serological types for some species of wild rodents. LA - Eng MH - Animal MH - Carrier State MH - Comparative Study MH - Disease Reservoirs MH - Hamsters MH - *Leptospira/pathogenicity MH - Leptospira interrogans/pathogenicity MH - Leptospirosis/microbiology/*veterinary MH - Mice MH - Rodent Diseases/*microbiology MH - Serotyping MH - Species Specificity MH - Weil's Disease/microbiology/veterinary PT - JOURNAL ARTICLE DA - 750504 DP - 1974 IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 388-95 SB - M CY - GERMANY, WEST IP - 3 VI - 228 JC - Y52 EM - 7506 PMID- 4155856 CU - 94 SO - Zentralbl Bakteriol [Orig A] 1974;228(3):388-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 75105258 AU - Fuchs GH AU - Burger G TI - [Standardizing in sero-diagnostic leptospirose investigations (author's transl)] LA - Ger MH - Agglutination Tests/methods/standards MH - Diagnostic Errors MH - English Abstract MH - Leptospirosis/*diagnosis MH - Photometry/methods MH - Serodiagnosis/*standards MH - Serotyping PT - JOURNAL ARTICLE DA - 750504 DP - 1974 IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 378-87 SB - M CY - GERMANY, WEST IP - 3 VI - 228 JC - Y52 EM - 7506 PMID- 4155855 CU - 94 TT - Standardisierungsprobleme bei serodiagnostischen Leptospirose- Untersuchungen EA - A SO - Zentralbl Bakteriol [Orig A] 1974;228(3):378-87 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75105257 AU - Yanagawa R AU - Shinagawa M AU - Takashima I TI - Serological studies of Leptospiras by immunodiffusion. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial/analysis MH - Comparative Study MH - Cross Reactions MH - Genotype MH - Immune Sera MH - Immunodiffusion MH - Leptospira/*immunology MH - Rabbits/immunology MH - Serotyping MH - Sodium Dodecyl Sulfate MH - Species Specificity PT - JOURNAL ARTICLE DA - 750504 DP - 1974 IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 369-77 SB - M CY - GERMANY, WEST IP - 3 VI - 228 JC - Y52 EM - 7506 PMID- 4155854 CU - 94 SO - Zentralbl Bakteriol [Orig A] 1974;228(3):369-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [32 medline neighbors] UI - 75061940 AU - Matossian RM AU - Ibrahim J TI - Rats, flies and mosquitos of Lebanon: pests, reservoirs and vectors of disease. LA - Eng MH - Animal MH - Arbovirus Infections/transmission MH - Bites and Stings MH - Cattle MH - *Culicidae MH - Dengue/transmission MH - *Diptera MH - *Disease Reservoirs MH - *Disease Vectors MH - Dogs MH - Dysentery, Bacillary/transmission MH - Fleas MH - Human MH - Lebanon MH - Leptospirosis/transmission MH - Malaria/transmission MH - Plague/transmission MH - Rabies/transmission MH - *Rats MH - Salmonella Infections/transmission MH - Sanitation MH - Swine MH - Trichinosis/transmission MH - Typhus, Endemic Flea-Borne/transmission MH - West Nile Virus PT - JOURNAL ARTICLE PT - REVIEW DA - 750319 DP - 1974 IS - 0023-9852 TA - J Med Liban PG - 375-81 CY - LEBANON IP - 4 VI - 27 JC - J1Z EM - 7504 RF - 18 PMID- 4155006 CU - 94 SO - J Med Liban 1974;27(4):375-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [168 medline neighbors] UI - 77102943 AU - South PJ AU - Stoenner HG TI - The control of outbreaks of leptospriosis in beef cattle by simultaneous vaccination and treatment with dihydrostreptomycin. LA - Eng MH - Abortion, Veterinary/prevention & control MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - Dihydrostreptomycin Sulfate/*therapeutic use MH - Female MH - Leptospirosis/prevention & control/*veterinary MH - Pregnancy MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 770315 DP - 1974 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 126-30 CY - UNITED STATES IP - 78 JC - PY5 EM - 7705 PMID- 4143491 CU - 95 SO - Proc Annu Meet U S Anim Health Assoc 1974;(78):126-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 75207542 AU - Malloux M TI - [Leptospiroses in tropical medicine. Epidemiology and diagnosis on Reunion Island and in French Polynesia (Tahiti)] LA - Fre MH - Africa MH - Animal MH - Antigen-Antibody Reactions MH - Comparative Study MH - Diagnosis, Differential MH - Disease Reservoirs MH - English Abstract MH - Epitopes/*analysis MH - France MH - Human MH - Leptospira/*immunology/pathogenicity MH - Leptospirosis/*epidemiology/immunology/transmission MH - Microclimate MH - Polynesia MH - Portugal MH - Support, U.S. Gov't, Non-P.H.S. MH - Virulence MH - Water Microbiology MH - Water Supply/analysis MH - Zoonoses/transmission PT - JOURNAL ARTICLE DA - 751106 DP - 1974 Jan-Feb IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 30-6 SB - M CY - FRANCE IP - 1 VI - 67 JC - C4G EM - 7512 PMID- 4142863 CU - 95 TT - Les leptospiroses en medecine tropicale. Epidemiologie et diagnostics a la reunion et en Polynesie francaise (Tahiti) EA - A SO - Bull Soc Pathol Exot Filiales 1974 Jan-Feb;67(1):30-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 75088466 AU - Johnson RT TI - Pathophysiology and epidemiology of acute viral infections of the nervous system. LA - Eng MH - Acute Disease MH - Animal MH - Axonal Transport MH - Blood-Brain Barrier MH - Central Nervous System Diseases/etiology/*physiopathology MH - Encephalitis/epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Reticuloendothelial System/physiopathology MH - Seasons MH - United States MH - Virus Diseases/epidemiology/etiology/*physiopathology PT - JOURNAL ARTICLE DA - 750419 DP - 1974 IS - 0091-3952 TA - Adv Neurol PG - 27-40 SB - M CY - UNITED STATES VI - 6 JC - 2NX EM - 7505 PMID- 4141220 CU - 95 SO - Adv Neurol 1974;6:27-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 74076707 AU - Tripathy DN AU - Hanson LE TI - Immunoperoxidase staining of leptospires. LA - Eng MH - Animal MH - Antigens, Bacterial/isolation & purification MH - Cattle/immunology MH - Formaldehyde MH - IgG MH - Immune Sera MH - *Immunologic Techniques MH - Leptospira/immunology/*isolation & purification MH - Methods MH - *Peroxidases MH - Plants/enzymology MH - Rabbits/immunology MH - *Staining PT - JOURNAL ARTICLE DA - 740308 DP - 1974 Jan IS - 0003-6919 TA - Appl Microbiol PG - 268-9 SB - M CY - UNITED STATES IP - 1 VI - 27 JC - 6K0 EM - 7404 PMID- 4129477 CU - 95 SO - Appl Microbiol 1974 Jan;27(1):268-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 74129507 AU - Michna SW AU - Ellis W TI - Incidence of antibodies for leptospirosis in dogs in Glasgow, and a comparison of the conventional (Schuffner's) and rapid microscopical agglutination (RMAT) tests. LA - Eng MH - *Agglutination Tests MH - Animal MH - Antibodies/*analysis MH - Antigens MH - Comparative Study MH - Dog Diseases/*diagnosis MH - Dogs MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis/*veterinary MH - Scotland PT - JOURNAL ARTICLE DA - 740528 DP - 1973 Dec 15 IS - 0042-4900 TA - Vet Rec PG - 633-4 SB - M CY - ENGLAND IP - 24 VI - 93 JC - XBS EM - 7407 PMID- 4785354 SO - Vet Rec 1973 Dec 15;93(24):633-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 74132673 AU - Cherkasskii BL TI - [Epidemiology of zoonoses. II. Characteristics of the territorial distribution of incidence of zoonoses along the population of the USSR] LA - Rus MH - Animal MH - Anthrax/epidemiology MH - Brucellosis/epidemiology MH - Encephalitis, Tick-Borne/epidemiology MH - English Abstract MH - Hemorrhagic Fevers, Viral/epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Ornithosis/epidemiology MH - Q Fever/epidemiology MH - Rabies/epidemiology MH - Salmonella Infections/epidemiology MH - Tularemia/epidemiology MH - USSR MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 740529 DP - 1973 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 34-42 SB - M CY - USSR IP - 12 VI - 50 JC - Y9O EM - 7407 PMID- 4799055 CU - 89 TT - Nekotorye voprosy epidemiologii zoonozov. Soobshchenie II. Kharakteristika territorial'nogo raspredeleniia zabolevaemosti zoonozami naseleniia SSS. SO - Zh Mikrobiol Epidemiol Immunobiol 1973 Dec;50(12):34-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 74051761 AU - Fraser DW AU - Glosser JW AU - Francis DP AU - Phillips CJ AU - Feeley JC AU - Sulzer CR TI - Leptospirosis caused by serotype Fort-Bragg. A suburban outbreak. LA - Eng MH - Adult MH - Agglutination Tests MH - Animal MH - Child MH - Child, Preschool MH - Disease Outbreaks MH - *Disease Reservoirs MH - Dog Diseases/diagnosis/microbiology MH - Dogs MH - Female MH - Human MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/microbiology/veterinary MH - Male MH - Middle Age MH - Oregon MH - Serotyping MH - Urine/microbiology MH - *Zoonoses PT - JOURNAL ARTICLE DA - 740211 DP - 1973 Dec IS - 0003-4819 TA - Ann Intern Med PG - 786-9 SB - A SB - M CY - UNITED STATES IP - 6 VI - 79 JC - 5A6 EM - 7403 PMID- 4796910 CU - 88 SO - Ann Intern Med 1973 Dec;79(6):786-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 74294048 AU - Rensburg WJ van TI - [Isolation of Leptospira canicola in swine and dogs in South Africa] LA - Afr MH - Animal MH - *Dog Diseases/epidemiology/microbiology MH - Dogs MH - English Abstract MH - Female MH - Leptospira canicola/*isolation & purification MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - South Africa MH - Swine MH - *Swine Diseases/epidemiology/microbiology PT - JOURNAL ARTICLE DA - 741111 DP - 1973 Dec TA - J S Afr Vet Assoc PG - 435-6 CY - SOUTH AFRICA IP - 4 VI - 44 JC - JZH EM - 7412 RO - O:45 RO - C:29 PMID- 4794501 CU - 89 TT - Isolasie van Leptospira canicola by varke en honde in Suid-Afrika EA - A SO - J S Afr Vet Assoc 1973 Dec;44(4):435-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 74136671 AU - Barsoum IS AU - Moch RW AU - Botros BA AU - Kaiser MN TI - Leptospires isolated from wild mammals in Egypt. LA - Eng MH - Animal MH - Disease Reservoirs MH - Egypt MH - Foxes MH - Hemagglutination Tests MH - Leptospira/*isolation & purification MH - Leptospira interrogans/isolation & purification MH - *Mammals MH - Mice MH - Rats MH - Rodentia PT - JOURNAL ARTICLE DA - 740604 DP - 1973 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 362-4 SB - M CY - NETHERLANDS IP - 4 VI - 25 JC - WGJ EM - 7407 PMID- 4786650 SO - Trop Geogr Med 1973 Dec;25(4):362-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 74051797 AU - Helmer RE 3d AU - Millsaps RD TI - Letter: Hypoglycorrachia in leptospirosis. LA - Eng MH - Adult MH - Case Report MH - Glucose/*cerebrospinal fluid MH - Human MH - Leptospirosis/*cerebrospinal fluid/diagnosis/drug therapy MH - Male MH - Penicillin G, Procaine/therapeutic use MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 740211 DP - 1973 Dec IS - 0003-4819 TA - Ann Intern Med PG - 912 SB - A SB - M CY - UNITED STATES IP - 6 VI - 79 JC - 5A6 EM - 7403 PMID- 4761927 SO - Ann Intern Med 1973 Dec;79(6):912 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 74051777 AU - Reif JS AU - Marshak RR TI - Editorial: Leptospirosis: a contemporary zoonosis. LA - Eng MH - Animal MH - Carrier State MH - *Disease Reservoirs MH - *Dog Diseases MH - Dogs MH - Ecology MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Rats MH - United States MH - Vaccination MH - *Zoonoses PT - JOURNAL ARTICLE DA - 740211 DP - 1973 Dec IS - 0003-4819 TA - Ann Intern Med PG - 893-4 SB - A SB - M CY - UNITED STATES IP - 6 VI - 79 JC - 5A6 EM - 7403 PMID- 4761913 CU - 88 SO - Ann Intern Med 1973 Dec;79(6):893-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74258025 AU - Ellinghausen HC Jr TI - Virulence, nutrition and antigenicity of Leptospira interrogans serotype Pomona in supplemented and nutrient deleted bovine albumin medium. LA - Eng MH - Antigens, Bacterial MH - Bacteriological Techniques MH - Cell Division MH - Cells, Cultured/immunology/physiology MH - Culture Media MH - Leptospira/immunology/*isolation & purification/physiology MH - Nutrition MH - Thiamine/metabolism MH - Virulence MH - Vitamin B 12/metabolism PT - JOURNAL ARTICLE DA - 740820 DP - 1973 Dec IS - 0300-5410 TA - Ann Microbiol (Paris) PG - 477-93 CY - FRANCE IP - 4 VI - 124 JC - 5JY EM - 7410 RO - O:41 RO - C:15 PMID- 4599959 CU - 90 SO - Ann Microbiol (Paris) 1973 Dec;124(4):477-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 74067314 AU - Ellinghausen HC Jr TI - Death and lysis of leptospirae when cultured in asbestos-filtered growth media. LA - Eng MH - Agglutination Tests MH - Antigens, Bacterial/analysis MH - Asbestos MH - Bacteriological Techniques MH - Bacteriolysis MH - *Culture Media MH - Densitometry MH - *Filtration MH - Leptospira/*growth & development/immunology/pathogenicity MH - Serotyping MH - Serum Albumin, Bovine MH - Species Specificity MH - Time Factors MH - Virulence MH - Water PT - JOURNAL ARTICLE DA - 740227 DP - 1973 Dec IS - 0003-6919 TA - Appl Microbiol PG - 959-68 SB - M CY - UNITED STATES IP - 6 VI - 26 JC - 6K0 EM - 7404 PMID- 4588200 CU - 90 SO - Appl Microbiol 1973 Dec;26(6):959-68 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 74051760 AU - Feigin RD AU - Lobes LA Jr AU - Anderson D AU - Pickering L TI - Human leptospirosis from immunized dogs. LA - Eng MH - Adolescence MH - Animal MH - Disease Outbreaks MH - *Disease Reservoirs MH - Dog Diseases/diagnosis/*epidemiology/microbiology MH - Dogs MH - Female MH - Fluorescent Antibody Technique MH - Human MH - Immunization MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/genetics/microbiology/veterinary MH - Male MH - Middle Age MH - Missouri MH - Rats MH - Rodent Diseases/diagnosis/*epidemiology/microbiology MH - Urine/microbiology MH - *Zoonoses PT - JOURNAL ARTICLE DA - 740211 DP - 1973 Dec IS - 0003-4819 TA - Ann Intern Med PG - 777-85 SB - A SB - M CY - UNITED STATES IP - 6 VI - 79 JC - 5A6 EM - 7403 PMID- 4586815 CU - 90 SO - Ann Intern Med 1973 Dec;79(6):777-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 74149464 AU - Chang A AU - Faine S TI - Effect of anti-cell and anti-axial filament sera on Leptospira. LA - Eng MH - Absorption MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial MH - *Antigens, Bacterial MH - Bacteriolysis MH - Cell Movement MH - Heat MH - Immune Sera/*pharmacology MH - Immunodiffusion MH - Leptospira/cytology/*immunology MH - Microscopy, Electron MH - Organoids/*immunology MH - Rabbits/immunology PT - JOURNAL ARTICLE DA - 740625 DP - 1973 Dec IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 847-56 SB - M CY - AUSTRALIA IP - 6 VI - 51 JC - 9FW EM - 7408 PMID- 4207491 CU - 91 SO - Aust J Exp Biol Med Sci 1973 Dec;51(6):847-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [64 medline neighbors] UI - 74132663 AU - Kats LN TI - [Submicroscopic structure of the bacterial cell wall (review of the literature)] LA - Rus MH - Bacillus anthracis/cytology MH - Bacillus cereus/cytology MH - Bacillus megaterium/cytology MH - Bacteria/*cytology MH - *Cell Wall MH - Clostridium/cytology MH - Corynebacterium diphtheriae/cytology MH - Escherichia coli/cytology MH - Francisella tularensis/cytology MH - Halobacterium/cytology MH - Klebsiella pneumoniae/cytology MH - Lactobacillus/cytology MH - Leptospira/cytology MH - Micrococcus/cytology MH - Nitrobacter/cytology MH - Proteus vulgaris/cytology MH - Shigella flexneri/cytology MH - Spirillum/cytology MH - Spirochaetales/cytology MH - Staphylococcus/cytology MH - Streptococcus/cytology MH - Thiobacillus thiooxidans/cytology MH - Treponema pallidum/cytology MH - Vibrio cholerae/cytology MH - Yersinia pestis/cytology PT - JOURNAL ARTICLE PT - REVIEW DA - 740529 DP - 1973 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 105-13 SB - M CY - USSR IP - 12 VI - 50 JC - Y9O EM - 7407 RF - 119 PMID- 4206610 CU - 91 TT - Submikroskopicheskaia struktura kletochnoi stenki u bakterii (obzor literatury. SO - Zh Mikrobiol Epidemiol Immunobiol 1973 Dec;50(12):105-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 74252143 AU - Kmety E AU - Lataste-Dorolle C TI - [Factorial analysis of the leptospiral Grippotyphosa serogroup] LA - Fre MH - Animal MH - *Antigens, Bacterial MH - Cross Reactions MH - English Abstract MH - Epidemiology MH - Epitopes MH - Geography MH - Hemagglutination Tests MH - Human MH - Immune Sera MH - Leptospira/classification/*immunology MH - Serotyping MH - Statistics PT - JOURNAL ARTICLE DA - 740820 DP - 1973 Dec IS - 0300-5410 TA - Ann Microbiol (Paris) PG - 495-503 CY - FRANCE IP - 4 VI - 124 JC - 5JY EM - 7410 RO - O:41 RO - C:15 PMID- 4134226 CU - 95 TT - Analyse factoriello du serogroupe leptospirien Grippotyphosa EA - A SO - Ann Microbiol (Paris) 1973 Dec;124(4):495-503 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 74114835 AU - Birch-Andersen A AU - Hovind Hougen K AU - Borg-Petersen C TI - Electron microscopy of Leptospira. 1. Leptospira strain Pomona. LA - Eng MH - Animal MH - Cell Nucleus MH - Cell Wall MH - Cytoplasm MH - Formaldehyde/diagnostic use MH - Leptospira/*cytology MH - Microscopy, Electron MH - Microtubules MH - Osmium/diagnostic use MH - Ribosomes MH - Staining PT - JOURNAL ARTICLE DA - 740503 DP - 1973 Dec IS - 0365-5571 TA - Acta Pathol Microbiol Scand [B] Microbiol Immunol PG - 665-76 SB - M CY - DENMARK IP - 6 VI - 81 JC - API EM - 7406 PMID- 4131382 CU - 95 SO - Acta Pathol Microbiol Scand [B] Microbiol Immunol 1973 Dec;81(6):665-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 74031521 AU - Nicholls H TI - Letter: Penicillin in leptospirosis. LA - Eng MH - Human MH - Leptospirosis/*drug therapy MH - Penicillin G, Procaine/*therapeutic use PT - JOURNAL ARTICLE DA - 740117 DP - 1973 Nov 3 IS - 0007-1447 TA - Br Med J PG - 301 SB - A SB - M CY - ENGLAND IP - 887 VI - 4 JC - B4W EM - 7402 PMID- 4753261 SO - Br Med J 1973 Nov 3;4(887):301 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 74012693 AU - Nelson KE AU - Ager EA AU - Galton MM AU - Gillespie RW AU - Sulzer CR TI - An outbreak of leptospirosis in Washington state. LA - Eng MH - Adolescence MH - Agglutination Tests MH - Animal MH - Antibodies/isolation & purification MH - Antigens/analysis MH - Cattle MH - Child MH - Cross Reactions MH - Disease Outbreaks/*epidemiology MH - Disease Vectors MH - Epidemiologic Methods MH - Female MH - Guinea Pigs MH - Human MH - Leptospira/classification MH - Leptospirosis/diagnosis/*epidemiology/immunology MH - Male MH - Rats MH - Serotyping MH - Swimming MH - Washington MH - Water Microbiology MH - Water Pollution PT - JOURNAL ARTICLE DA - 731217 DP - 1973 Nov IS - 0002-9262 TA - Am J Epidemiol PG - 336-47 SB - M CY - UNITED STATES IP - 5 VI - 98 JC - 3H3 EM - 7401 PMID- 4795719 CU - 88 SO - Am J Epidemiol 1973 Nov;98(5):336-47 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74123579 AU - Watson AD AU - Wannan JS TI - Letter: The incidence of leptospiral agglutinins in domestic cats in Sydney. LA - Eng MH - Agglutinins/*analysis MH - Animal MH - Antibodies, Bacterial/*analysis MH - Australia MH - Cat Diseases/*epidemiology MH - Cats MH - Female MH - Leptospira/*immunology MH - Leptospirosis/epidemiology/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 740517 DP - 1973 Nov IS - 0005-0423 TA - Aust Vet J PG - 545 SB - M CY - AUSTRALIA IP - 11 VI - 49 JC - 9IE EM - 7407 PMID- 4784196 CU - 88 SO - Aust Vet J 1973 Nov;49(11):545 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 74106932 AU - Fuchs GH AU - Burger G TI - [Application of the critical path method as a planning model in microbiology] LA - Ger MH - Comparative Study MH - Germany, East MH - Human MH - Leptospirosis/diagnosis MH - *Microbiology MH - Operations Research MH - Serodiagnosis MH - *Task Performance and Analysis PT - JOURNAL ARTICLE DA - 740424 DP - 1973 Nov IS - 0049-8610 TA - Z Gesamte Hyg PG - 820-5 CY - GERMANY, EAST IP - 11 VI - 19 JC - XUO EM - 7406 PMID- 4780391 TT - Zur Anwendbarkeit der Methode des kritischen Weges als Planungsmodell in der medizinischen Mikrobiologie. SO - Z Gesamte Hyg 1973 Nov;19(11):820-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 74071743 AU - Shenberg E AU - Torten M TI - A new leptospiral vaccine for use in man. I. Development of a vaccine from Leptospira grown on a chemically defined medium. LA - Eng MH - Agglutinins MH - Animal MH - Bacterial Vaccines/adverse effects/*standards MH - Blood Proteins MH - *Culture Media MH - Hamsters MH - Human MH - Israel MH - Leptospira/*growth & development MH - Leptospirosis/immunology MH - Mice PT - JOURNAL ARTICLE DA - 740305 DP - 1973 Nov IS - 0022-1899 TA - J Infect Dis PG - 642-6 SB - A SB - M CY - UNITED STATES IP - 5 VI - 128 JC - IH3 EM - 7404 PMID- 4768915 SO - J Infect Dis 1973 Nov;128(5):642-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 74060924 AU - Barkin RM TI - Human leptospirosis in Texas: a nine-year overview. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Female MH - Human MH - Infant MH - Infant, Newborn MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Texas PT - JOURNAL ARTICLE DA - 740222 DP - 1973 Nov IS - 0040-4470 TA - Tex Med PG - 64-8 CY - UNITED STATES IP - 11 VI - 69 JC - VNA EM - 7404 PMID- 4764631 CU - 88 SO - Tex Med 1973 Nov;69(11):64-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 74057076 AU - Ellinghausen HC Jr TI - Growth temperatures, virulence, survival, and nutrition of leptospires. LA - Eng MH - Animal MH - Culture Media MH - Hamsters MH - Heat MH - Kidney/microbiology MH - Leptospira/*growth & development/pathogenicity MH - Liver/microbiology MH - Nutrition MH - Preservation, Biological MH - Serum Albumin, Bovine MH - Swine MH - Time Factors MH - Virulence PT - JOURNAL ARTICLE DA - 740214 DP - 1973 Nov IS - 0022-2615 TA - J Med Microbiol PG - 487-97 SB - M CY - ENGLAND IP - 4 VI - 6 JC - J2N EM - 7403 PMID- 4763972 CU - 90 SO - J Med Microbiol 1973 Nov;6(4):487-97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 74052900 AU - Sulzer CR AU - Jones WL TI - Evaluation of a hemagglutination test for human leptospirosis. LA - Eng MH - Animal MH - Antigens, Bacterial/analysis MH - Comparative Study MH - Erythrocytes/immunology MH - Evaluation Studies MH - Hemagglutination Tests MH - Human MH - Immune Sera MH - Leptospirosis/diagnosis/*immunology MH - Methods MH - Serotyping MH - Sheep PT - JOURNAL ARTICLE DA - 740212 DP - 1973 Nov IS - 0003-6919 TA - Appl Microbiol PG - 655-7 SB - M CY - UNITED STATES IP - 5 VI - 26 JC - 6K0 EM - 7403 PMID- 4762389 CU - 90 SO - Appl Microbiol 1973 Nov;26(5):655-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 74028356 AU - Welsh JD TI - Letter: Leptospirosis in Vietnam. LA - Eng MH - Human MH - Leptospirosis/*epidemiology MH - Vietnam PT - JOURNAL ARTICLE DA - 740115 DP - 1973 Nov IS - 0003-4819 TA - Ann Intern Med PG - 756 SB - A SB - M CY - UNITED STATES IP - 5 VI - 79 JC - 5A6 EM - 7402 PMID- 4751758 CU - 88 SO - Ann Intern Med 1973 Nov;79(5):756 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 74071744 AU - Torten M AU - Shenberg E AU - Gerichter CB AU - Neuman P AU - Klingberg MA TI - A new leptospiral vaccine for use in man. II. Clinical and serologic evaluation of a field trial with volunteers. LA - Eng MH - Agglutination Tests MH - Bacterial Vaccines/adverse effects/*standards MH - Clinical Trials MH - Human MH - Israel MH - *Leptospira MH - Leptospirosis/*immunology MH - Placebos MH - Skin Tests PT - CLINICAL TRIAL PT - JOURNAL ARTICLE PT - RANDOMIZED CONTROLLED TRIAL DA - 740305 DP - 1973 Nov IS - 0022-1899 TA - J Infect Dis PG - 647-51 SB - A SB - M CY - UNITED STATES IP - 5 VI - 128 JC - IH3 EM - 7404 RO - M:RCT PMID- 4588702 CU - 95 SO - J Infect Dis 1973 Nov;128(5):647-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 74022052 AU - Branson D TI - Timely topics in microbiology, 1970-1971: miscellaneous bacteria, antibiotics. LA - Eng MH - Actinomycetales MH - *Antibiotics MH - *Bacteria MH - *Bibliography MH - Female MH - Human MH - Leptospira MH - Mycobacterium MH - Mycoplasma MH - Rickettsia MH - Treponema PT - BIBLIOGRAPHY PT - JOURNAL ARTICLE DA - 740105 DP - 1973 Nov IS - 0002-9335 TA - Am J Med Technol PG - 472-82 SB - M CY - UNITED STATES IP - 11 VI - 39 JC - 3LO EM - 7402 PMID- 4584007 CU - 90 SO - Am J Med Technol 1973 Nov;39(11):472-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [8 medline neighbors] UI - 74010755 AU - Berman SJ AU - Irving GS AU - Kundin WD AU - Gunning JJ AU - Watten RH TI - Epidemiology of the acute fevers of unknown origin in South Vietnam: effect of laboratory support upon clinical diagnosis. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Arbovirus Infections/diagnosis MH - Diagnosis, Differential MH - *Diagnosis, Laboratory MH - Disease Vectors MH - Encephalitis, Japanese/diagnosis MH - Environmental Exposure MH - Epidemiologic Methods MH - Fever of Unknown Origin/diagnosis/*epidemiology MH - Geography MH - Human MH - Leptospirosis/diagnosis MH - Male MH - Military Medicine MH - Scrub Typhus/diagnosis MH - Seasons MH - Serodiagnosis MH - United States MH - Vietnam MH - Water Supply PT - JOURNAL ARTICLE DA - 731216 DP - 1973 Nov IS - 0002-9637 TA - Am J Trop Med Hyg PG - 796-801 SB - A SB - M CY - UNITED STATES IP - 6 VI - 22 JC - 3ZQ EM - 7401 PMID- 4355456 CU - 93 SO - Am J Trop Med Hyg 1973 Nov;22(6):796-801 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 74010913 AU - Lawson JH TI - Letter: Penicillin in leptospirosis. LA - Eng MH - Cell Count MH - Human MH - Leptospirosis/cerebrospinal fluid/*drug therapy MH - Penicillins/*therapeutic use MH - Time Factors PT - JOURNAL ARTICLE DA - 731216 DP - 1973 Oct 13 IS - 0007-1447 TA - Br Med J PG - 109 SB - A SB - M CY - ENGLAND IP - 884 VI - 4 JC - B4W EM - 7401 PMID- 4745332 CU - 90 SO - Br Med J 1973 Oct 13;4(884):109 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [31 medline neighbors] UI - 74106134 AU - Kiktenko VS AU - Bakulina NA AU - Levina LF TI - [Granule formation in Leptospira] LA - Rus MH - Cytoplasmic Granules MH - English Abstract MH - Formaldehyde/pharmacology MH - Heat MH - Immune Sera/pharmacology MH - Leptospira interrogans/*cytology/drug effects MH - Microscopy, Electron MH - Nystatin/pharmacology MH - Penicillin G/pharmacology MH - Sodium Chloride/pharmacology MH - Ultrasonics PT - JOURNAL ARTICLE DA - 740424 DP - 1973 Oct IS - 0006-4041 TA - Biull Eksp Biol Med PG - 83-6 SB - M CY - USSR IP - 10 VI - 75 JC - A74 EM - 7406 PMID- 4780164 TT - K voprosy o granuloobrazovanii u leptospir. SO - Biull Eksp Biol Med 1973 Oct;75(10):83-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 74053909 AU - Reiner E AU - Hicks JJ AU - Sulzer CR TI - Leptospiral taxonomy by pyrolysis-gas-liquid chromatography. LA - Eng MH - *Chromatography, Gas MH - Heat MH - Leptospira/analysis/*classification MH - Leptospira canicola/classification MH - Methods MH - Serotyping PT - JOURNAL ARTICLE DA - 740212 DP - 1973 Oct IS - 0008-4166 TA - Can J Microbiol PG - 1203-6 SB - M CY - CANADA IP - 10 VI - 19 JC - CJ3 EM - 7403 PMID- 4762796 CU - 90 SO - Can J Microbiol 1973 Oct;19(10):1203-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 74021097 AU - Stalheim OH TI - Failure to reproduce acute porcine leptospirosis by physiologic stress or concurrent infections. LA - Eng MH - Animal MH - Ascariasis/complications/veterinary MH - Cholesterol, Dietary/administration & dosage MH - Germ-Free Life MH - Hog Cholera/complications/microbiology MH - Hypercholesterolemia/complications/veterinary MH - Infection/*veterinary MH - Injections, Intramuscular MH - Kidney Diseases/etiology/veterinary MH - Leptospirosis/complications/etiology/*veterinary MH - Mycoplasma Infections/complications/veterinary MH - RNA Viruses MH - Salmonella Infections, Animal/complications MH - Stress/complications/*veterinary MH - Swine MH - Swine Diseases/*etiology PT - JOURNAL ARTICLE DA - 740105 DP - 1973 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1257-60 SB - M CY - UNITED STATES IP - 10 VI - 34 JC - 40C EM - 7402 PMID- 4748239 SO - Am J Vet Res 1973 Oct;34(10):1257-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 74021096 AU - Morsi HM AU - Shibley GP AU - Strother HL TI - Antibody response of swine to Leptospira canicola and Leptospira icterohaemorrhagiae. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antibody Formation MH - Bacterial Vaccines/administration & dosage MH - Hamsters MH - Immunization, Passive MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Leptospirosis/immunology/veterinary MH - Swine/*immunology MH - Swine Diseases/immunology MH - Vaccination PT - JOURNAL ARTICLE DA - 740105 DP - 1973 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1253-5 SB - M CY - UNITED STATES IP - 10 VI - 34 JC - 40C EM - 7402 PMID- 4748238 SO - Am J Vet Res 1973 Oct;34(10):1253-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 74081716 AU - Ris DR AU - Lake DE AU - Holland JT TI - The isolation of Leptospira serotypes Copenhageni and Ballum from healthy calves. LA - Eng MH - Animal MH - Carrier State/microbiology/*veterinary MH - Cattle MH - Cattle Diseases/*microbiology MH - Female MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/*veterinary MH - Serotyping MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 740318 DP - 1973 Oct IS - 0048-0169 TA - N Z Vet J PG - 218-20 CY - NEW ZEALAND IP - 10 VI - 21 JC - OBZ EM - 7405 PMID- 4520929 CU - 88 SO - N Z Vet J 1973 Oct;21(10):218-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [4 medline neighbors] UI - 74124128 AU - Vaughn HW AU - Knight RR AU - Frank FW TI - A study of reproduction, disease and physiological blood and serum values in Idaho elk. LA - Eng MH - Anaplasmosis/immunology MH - Animal MH - Artiodactyla/metabolism/*physiology MH - Blood Glucose/analysis MH - Blood Proteins/analysis MH - Bluetongue/immunology MH - Bovine Virus Diarrhea-Mucosal Disease/immunology MH - Brucellosis/immunology/veterinary MH - Cattle MH - Electrolytes/blood MH - Erythrocyte Count MH - Female MH - Hematocrit MH - Hemoglobins/analysis MH - Idaho MH - Infectious Bovine Rhinotracheitis/immunology MH - Leptospirosis/immunology/veterinary MH - Leukocyte Count MH - Male MH - Pregnancy MH - *Reproduction MH - Sheep MH - Vibrio Infections/immunology/veterinary PT - JOURNAL ARTICLE DA - 740517 DP - 1973 Oct IS - 0090-3558 TA - J Wildl Dis PG - 296-301 SB - M CY - UNITED STATES IP - 4 VI - 9 JC - KEM EM - 7407 PMID- 4361504 CU - 93 SO - J Wildl Dis 1973 Oct;9(4):296-301 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [33 medline neighbors] UI - 74021111 AU - Schiemann DA TI - Thiosulfate and survival of Leptospira autumnalis Akiyami A. LA - Eng MH - Calcium/pharmacology MH - Cobalt/pharmacology MH - Copper/pharmacology MH - Culture Media MH - Cystine/pharmacology MH - Edetic Acid/pharmacology MH - Leptospira/*drug effects/metabolism/physiology MH - Methionine/pharmacology MH - Nickel/pharmacology MH - Osmolar Concentration MH - Sodium Chloride/pharmacology MH - Sulfides/metabolism MH - Sulfur Radioisotopes MH - Thiosulfates/metabolism/*pharmacology PT - JOURNAL ARTICLE DA - 740105 DP - 1973 Oct IS - 0002-9645 TA - Am J Vet Res PG - 1345-50 SB - M CY - UNITED STATES IP - 10 VI - 34 JC - 40C EM - 7402 PMID- 4201223 CU - 91 SO - Am J Vet Res 1973 Oct;34(10):1345-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 74114828 AU - Stempien R AU - Dymowska Z AU - Kaminska D AU - Nasilowska M TI - [Studies on the haemolytic properties of leptospira with the application of a radioisotopic method (author's transl)] LA - Ger MH - Antigens, Bacterial MH - Chromium Radioisotopes MH - English Abstract MH - Erythrocytes/immunology MH - *Hemolysis MH - Human MH - *Isotope Labeling MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Methods MH - Serotyping MH - Species Specificity PT - JOURNAL ARTICLE DA - 740502 DP - 1973 Oct IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 492-5 SB - M CY - GERMANY, WEST IP - 4 VI - 224 JC - Y52 EM - 7406 PMID- 4150116 CU - 94 TT - Untersuchungen uber hamolytische Eigenschaften der Leptospiren unter Anwendung der Radioisotopenmethode. SO - Zentralbl Bakteriol [Orig A] 1973 Oct;224(4):492-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 74075081 AU - Ivanyi J AU - Pluhar J AU - Libor J TI - [Leptospirosis in South-East Hungary] LA - Ger MH - Adolescence MH - Adult MH - Aged MH - Disease Outbreaks MH - Female MH - Human MH - Hungary MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Seasons PT - JOURNAL ARTICLE DA - 740307 DP - 1973 Sep 28 IS - 0025-8512 TA - Med Welt PG - 1484-6 CY - GERMANY, WEST IP - 39 VI - 24 JC - MIM EM - 7404 PMID- 4770440 CU - 88 TT - Leptospirosen in Sudost-Ungarn. SO - Med Welt 1973 Sep 28;24(39):1484-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [54 medline neighbors] UI - 74004137 AU - Schroeder RJ AU - Delli Quadri CA AU - McIntyre RW AU - Walker WA TI - Marine mammal disease surveillance program in Los Angeles County. LA - Eng MH - Animal MH - Animal Diseases/*epidemiology MH - California MH - *Cetacea MH - Dipetalonema MH - Dolphins MH - Encephalitis/veterinary MH - Filariasis/veterinary MH - Filarioidea MH - Gastritis/veterinary MH - Hepatitis, Animal/epidemiology MH - Leptospirosis/veterinary MH - Nematode Infections/veterinary MH - *Pinnipedia MH - Pneumonia/veterinary MH - Salmonella Infections, Animal/epidemiology MH - Wounds, Gunshot/veterinary PT - JOURNAL ARTICLE DA - 731211 DP - 1973 Sep 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 580-1 SB - M CY - UNITED STATES IP - 6 VI - 163 JC - HAV EM - 7401 PMID- 4795401 CU - 88 SO - J Am Vet Med Assoc 1973 Sep 15;163(6):580-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 74297045 AU - Buzzanca E AU - Frezza L AU - Montebianco Abenavoli S TI - [Use of cryolysate antigen for preparation of anti-Leptospira immune serums] LA - Ita MH - Animal MH - Antibody Formation MH - Antigen-Antibody Reactions MH - Antigens MH - English Abstract MH - *Immune Sera MH - Leptospira/*immunology MH - Leptospirosis/diagnosis MH - Rabbits PT - JOURNAL ARTICLE DA - 741106 DP - 1973 Sep IS - 0033-4979 TA - Quad Sclavo Diagn PG - 815-8 CY - ITALY IP - 3 VI - 9 JC - QLU EM - 7412 RO - O:46 RO - C:01 PMID- 4794811 TT - Impiego di antigene criolisato per la preparazione di sieri immuni anti- leptospire EA - A SO - Quad Sclavo Diagn 1973 Sep;9(3):815-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 74068686 AU - Safer M AU - Verenca C AU - Sandru C TI - [Competition method for control and purification of cultures of Leptospira acuicola] LA - Rum MH - Leptospira/*isolation & purification MH - Methods PT - JOURNAL ARTICLE DA - 740228 DP - 1973 Sep-Oct IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 469-74 CY - ROMANIA IP - 5 VI - 18 JC - MXQ EM - 7404 PMID- 4767731 CU - 90 TT - Metoda competitiei pentru controlul si purificarea culturilor de leptospire acvicole. SO - Microbiol Parazitol Epidemiol (Bucur) 1973 Sep-Oct;18(5):469-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74035584 AU - Hlavata Z TI - [Isolation of Leptospira andamana in Slovakia] LA - Slo MH - Czechoslovakia MH - English Abstract MH - Leptospira/*isolation & purification MH - Water Microbiology PT - JOURNAL ARTICLE DA - 740119 DP - 1973 Sep IS - 0006-9248 TA - Bratisl Lek Listy PG - 307-10 CY - CZECHOSLOVAKIA IP - 3 VI - 59 JC - B5N EM - 7402 PMID- 4755237 TT - Izolacia Leptospira andamana na Slovensku. SO - Bratisl Lek Listy 1973 Sep;59(3):307-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 74014776 AU - Shibley GP AU - Morsi HM AU - Strother HL AU - Clark M TI - Renal leptospirosis: exposure of vaccinated and nonvaccinated swine to Leptospira icterohaemorrhagiae and Leptospira canicola. LA - Eng MH - Animal MH - Bacterial Vaccines/administration & dosage MH - Biological Assay MH - Blood/microbiology MH - Hamsters MH - Injections, Intraperitoneal MH - Injections, Subcutaneous MH - Kidney Diseases/immunology/microbiology/*veterinary MH - Leptospira canicola/*immunology/isolation & purification MH - Leptospira interrogans/*immunology/isolation & purification MH - Leptospirosis/immunology/microbiology/*veterinary MH - Swine MH - Swine Diseases/*immunology/microbiology MH - Urine/microbiology MH - Vaccination/*veterinary MH - Weil's Disease/veterinary PT - JOURNAL ARTICLE DA - 731219 DP - 1973 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1171-3 SB - M CY - UNITED STATES IP - 9 VI - 34 JC - 40C EM - 7401 PMID- 4747037 SO - Am J Vet Res 1973 Sep;34(9):1171-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 74003733 AU - Barkin RM AU - Glosser JW TI - Leptospirosis--an epidemic in children. LA - Eng MH - Adolescence MH - Agglutination Tests MH - Animal MH - Child MH - Child, Preschool MH - Disease Outbreaks/*epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - Human MH - Infant MH - Leptospira canicola/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/microbiology/veterinary MH - Texas MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 731211 DP - 1973 Sep IS - 0002-9262 TA - Am J Epidemiol PG - 184-91 SB - M CY - UNITED STATES IP - 3 VI - 98 JC - 3H3 EM - 7401 PMID- 4741839 CU - 88 SO - Am J Epidemiol 1973 Sep;98(3):184-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 73257142 AU - Wickenden TC TI - The vagaries of historical data. LA - Eng MH - Adult MH - Brucellosis/diagnosis MH - Florida MH - Histoplasmosis/diagnosis MH - Human MH - Leptospirosis/diagnosis MH - Male MH - *Medical History Taking MH - *Student Health Services PT - JOURNAL ARTICLE DA - 731115 DP - 1973 Sep IS - 0091-6757 TA - JFMA PG - 21-3 CY - UNITED STATES IP - 9 VI - 60 JC - KRW EM - 7312 PMID- 4732350 SO - JFMA 1973 Sep;60(9):21-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73250321 AU - Knight LL AU - Miller NG AU - White RJ TI - Cytotoxic factor in the blood and plasma of animals during leptospirosis. LA - Eng MH - Animal MH - Brain/immunology MH - *Cytotoxicity Tests, Immunologic MH - Hamsters MH - Hela Cells MH - Immunization MH - L Cells MH - Leptospira/classification/immunology MH - Leptospirosis/*immunology MH - Mice MH - Pasteurella/immunology PT - JOURNAL ARTICLE DA - 731109 DP - 1973 Sep IS - 0019-9567 TA - Infect Immun PG - 401-5 SB - M CY - UNITED STATES IP - 3 VI - 8 JC - GO7 EM - 7312 PMID- 4729930 SO - Infect Immun 1973 Sep;8(3):401-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 74156845 AU - Griffiths IR AU - Duncan ID AU - McQueen A AU - Quirk C AU - Miller R TI - Neuromuscular disease in dogs: some aspects of its investigation and diagnosis. LA - Eng MH - Animal MH - Biopsy MH - Dog Diseases/*diagnosis MH - Dogs MH - Electromyography MH - Female MH - Leptospirosis/veterinary MH - Leukemia, Myeloid/pathology/veterinary MH - Male MH - Masticatory Muscles MH - Muscle Denervation MH - Muscles/pathology MH - Muscular Atrophy/pathology/veterinary MH - Muscular Dystrophy/veterinary MH - Myasthenia Gravis/diagnosis/veterinary MH - Myotonia/pathology/veterinary MH - Nerve Degeneration MH - Neuromuscular Diseases/diagnosis/pathology/*veterinary MH - Toxoplasmosis, Animal/pathology PT - JOURNAL ARTICLE PT - REVIEW DA - 740705 DP - 1973 Sep IS - 0022-4510 TA - J Small Anim Pract PG - 533-54 CY - ENGLAND IP - 9 VI - 14 JC - K4N EM - 7408 RF - 64 PMID- 4596900 CU - 90 SO - J Small Anim Pract 1973 Sep;14(9):533-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 74013773 AU - Barton LL AU - Escobedo MB AU - Keating JP AU - Ternberg JL TI - Leptospirosis with acalculous cholecystitis. LA - Eng MH - Agglutination Tests MH - Animal MH - Child, Preschool MH - Cholecystitis/*etiology/radiography/surgery MH - Drainage MH - Female MH - Fever/etiology MH - Fluorescent Antibody Technique MH - Human MH - Jaundice/etiology MH - Leptospira/isolation & purification MH - Leptospirosis/*complications/diagnosis MH - Skin Diseases/etiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 731218 DP - 1973 Sep IS - 0002-922X TA - Am J Dis Child PG - 350-1 SB - A SB - M CY - UNITED STATES IP - 3 VI - 126 JC - 3GS EM - 7401 PMID- 4583536 CU - 90 SO - Am J Dis Child 1973 Sep;126(3):350-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 74260290 AU - Lavignette AM TI - Differential diagnosis and treatment of anterior uveitis. LA - Eng MH - Animal MH - Antibiotics/therapeutic use MH - Diagnosis, Differential MH - Dog Diseases/drug therapy/etiology MH - Dogs MH - Endophthalmitis/veterinary MH - Glucocorticoids/therapeutic use MH - Hepatitis, Infectious Canine/complications MH - Horse Diseases/drug therapy/etiology MH - Horses MH - Leptospirosis/veterinary MH - Mydriatics/therapeutic use MH - Onchocerciasis/veterinary MH - Uveitis/diagnosis/drug therapy/etiology/immunology/*veterinary PT - JOURNAL ARTICLE DA - 740819 DP - 1973 Sep IS - 0091-0279 TA - Vet Clin North Am PG - 503-14 CY - UNITED STATES IP - 3 VI - 3 JC - XBG EM - 7410 RO - O:45 RO - C:29 PMID- 4546005 CU - 89 SO - Vet Clin North Am 1973 Sep;3(3):503-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [18 medline neighbors] UI - 74014780 AU - Lavender JF AU - Bewsey BJ TI - Immunogenicity of canine distemper virus vaccine produced in a continuous cell line (LLC-MK2 cells). LA - Eng MH - Adenoviruses, Canine/immunology MH - Animal MH - *Antibody Formation MH - Cattle MH - Cell Line MH - Distemper/immunology MH - Distemper Virus, Canine/*growth & development/immunology MH - Dog Diseases/immunology MH - Dogs MH - Freeze Drying MH - Haplorhini MH - Hepatitis, Infectious Canine/immunology MH - Immune Sera MH - Kidney MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/veterinary MH - Methods MH - Neutralization Tests MH - Vaccines, Attenuated MH - *Viral Vaccines MH - Virus Cultivation MH - Virus Replication PT - JOURNAL ARTICLE DA - 731219 DP - 1973 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1189-94 SB - M CY - UNITED STATES IP - 9 VI - 34 JC - 40C EM - 7401 PMID- 4355770 CU - 93 SO - Am J Vet Res 1973 Sep;34(9):1189-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74120777 AU - Kislova IF AU - Bernasovskaia EP AU - Mogireva LA TI - [Immunochemical study of the antigens isolated from Leptospira] LA - Ukr MH - Antigens, Bacterial/*isolation & purification MH - Complement Fixation Tests MH - Culture Media MH - English Abstract MH - Hemagglutination Tests MH - Hemolytic Plaque Technique MH - Immunodiffusion MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 740516 DP - 1973 Sep-Oct IS - 0026-3664 TA - Mikrobiol Zh PG - 619-24 CY - USSR IP - 5 VI - 35 JC - MZ2 EM - 7407 PMID- 4205966 CU - 91 TT - Imunokhimichne vyvchennia antyheniv, vidilenykh z leptospir. SO - Mikrobiol Zh 1973 Sep-Oct;35(5):619-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74071085 AU - Famatiga EG TI - Leptospirosis in Philippine monkeys. LA - Eng MH - Agglutination Tests MH - Animal MH - Haplorhini MH - Leptospira/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Monkey Diseases/*epidemiology/immunology MH - Philippines PT - JOURNAL ARTICLE DA - 740302 DP - 1973 Sep IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 316-8 SB - M CY - THAILAND IP - 3 VI - 4 JC - UVN EM - 7404 PMID- 4203490 CU - 91 SO - Southeast Asian J Trop Med Public Health 1973 Sep;4(3):316-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 74029224 AU - Babudieri B AU - Carlos ER AU - Carlos ET Jr TI - Pathogenic leptospira isolated from toad kidneys. LA - Eng MH - Animal MH - *Bufo marinus MH - Disease Reservoirs MH - Kidney/*analysis MH - Leptospira/classification/growth & development/immunology/*isolation & purification/pathogenicity MH - Philippines MH - Serotyping PT - JOURNAL ARTICLE DA - 740115 DP - 1973 Sep IS - 0041-3232 TA - Trop Geogr Med PG - 297-9 SB - M CY - NETHERLANDS IP - 3 VI - 25 JC - WGJ EM - 7402 PMID- 4201686 CU - 91 SO - Trop Geogr Med 1973 Sep;25(3):297-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [92 medline neighbors] UI - 73226604 TI - Diseases from pets. LA - Eng MH - Adult MH - Animal MH - *Animals, Domestic MH - Birds MH - Cat-Scratch Disease/etiology MH - Cats MH - Child MH - *Disease Vectors MH - Dogs MH - Haplorhini MH - Human MH - Hypersensitivity/etiology MH - Larva Migrans/etiology MH - Larva Migrans, Visceral/etiology MH - Leptospirosis/etiology MH - Ornithosis/etiology MH - Pasteurella Infections/etiology MH - Pneumonia/etiology MH - Rabies/etiology MH - Salmonella Infections/etiology MH - Toxoplasmosis/etiology MH - Turtles MH - *Zoonoses PT - JOURNAL ARTICLE DA - 731002 DP - 1973 Aug 31 IS - 0025-732X TA - Med Lett Drugs Ther PG - 73-5 SB - A SB - M CY - UNITED STATES IP - 18 VI - 15 JC - M52 EM - 7311 PMID- 4198478 CU - 91 NI - A SO - Med Lett Drugs Ther 1973 Aug 31;15(18):73-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 74068187 AU - Gutschmidt HJ AU - Ziegelasch HJ TI - [Successful hemodialysis treatment of acute kidney failure in icterohemorrhagic leptospirosis (Weil's disease)] LA - Ger MH - Adult MH - Case Report MH - English Abstract MH - Female MH - *Hemodialysis MH - Human MH - Kidney Failure, Acute/complications/*therapy MH - Serotyping MH - Weil's Disease/*complications/microbiology PT - JOURNAL ARTICLE DA - 740227 DP - 1973 Aug 15 IS - 0044-2542 TA - Z Gesamte Inn Med PG - 508-10 SB - M CY - GERMANY, EAST IP - 16 VI - 28 JC - XUY EM - 7404 PMID- 4767600 TT - Erfolgreiche Hamodialysebehandlung eines akuten Nierenversagens bei Leptospirosis icterohaemorrhagiae (Morbus Weil. SO - Z Gesamte Inn Med 1973 Aug 15;28(16):508-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73233222 AU - Clein L TI - Penicillin in leptospirosis. LA - Eng MH - Human MH - Leptospirosis/*drug therapy MH - Penicillins/administration & dosage/*therapeutic use MH - Time Factors PT - JOURNAL ARTICLE DA - 731011 DP - 1973 Aug 11 IS - 0007-1447 TA - Br Med J PG - 354 SB - A SB - M CY - ENGLAND IP - 875 VI - 3 JC - B4W EM - 7311 PMID- 4723835 CU - 90 SO - Br Med J 1973 Aug 11;3(875):354 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73232324 AU - Mackay-Dick J TI - Leptospirosis in 1972. LA - Eng MH - Great Britain MH - Human MH - Leptospirosis/*drug therapy/epidemiology MH - Penicillins/*therapeutic use PT - JOURNAL ARTICLE DA - 731011 DP - 1973 Aug 4 IS - 0007-1447 TA - Br Med J PG - 293-4 SB - A SB - M CY - ENGLAND IP - 874 VI - 3 JC - B4W EM - 7311 PMID- 4723480 CU - 88 SO - Br Med J 1973 Aug 4;3(874):293-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 74125429 AU - Cherkasskii BL TI - [Epidemiology of zoonoses. I. Epidemiological characteristics of the incidence of zoonoses among the population of the USSR] LA - Rus MH - Adolescence MH - Animal MH - Anthrax/epidemiology MH - Brucellosis/epidemiology MH - Encephalitis, Tick-Borne/epidemiology MH - English Abstract MH - Hemorrhagic Fevers, Viral/epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Ornithosis/epidemiology MH - Q Fever/epidemiology MH - Rabies/epidemiology MH - Salmonella Infections/epidemiology MH - Seasons MH - Tularemia/epidemiology MH - USSR MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 740518 DP - 1973 Aug TA - Zh Mikrobiol Epidemiol Immunobiol PG - 3-9 SB - M CY - USSR IP - 8 VI - 50 JC - Y9O EM - 7407 PMID- 4798909 CU - 89 TT - Nekotorye voprosy epidemiologii zoonozov. I. Epidemiologicheskaia kharakteristika zabolevaemosti zoonozami naseleniia SSS. SO - Zh Mikrobiol Epidemiol Immunobiol 1973 Aug;50(8):3-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 74099513 AU - Hergt R AU - Krauss R TI - [Tarassov's leptospirosis with fatal course] LA - Ger MH - Abattoirs MH - Animal MH - Human MH - *Leptospirosis MH - Male MH - Middle Age MH - *Occupational Diseases MH - Swine PT - JOURNAL ARTICLE DA - 740405 DP - 1973 Aug IS - 0049-8610 TA - Z Gesamte Hyg PG - 589-91 CY - GERMANY, EAST IP - 8 VI - 19 JC - XUO EM - 7405 PMID- 4798311 CU - 85 TT - Tarassov-Leptospirose mit todlichem Ausgnag. SO - Z Gesamte Hyg 1973 Aug;19(8):589-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 74125416 AU - Zorina ZM AU - Martynova AP AU - Ivanova MN TI - [Dynamics of serum antibodies in patients with leptospirosis, caused by L. pomona, and in healthy vaccinated subjects] LA - Rus MH - Agglutinins/analysis MH - *Antibody Formation MH - *Bacterial Vaccines MH - English Abstract MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*immunology/prevention & control MH - Time Factors MH - *Vaccination PT - JOURNAL ARTICLE DA - 740518 DP - 1973 Aug TA - Zh Mikrobiol Epidemiol Immunobiol PG - 109-12 SB - M CY - USSR IP - 8 VI - 50 JC - Y9O EM - 7407 PMID- 4784581 CU - 90 TT - Dinamika syvorotochnykh antitel u bol'nykh leptospirozom, vyzvannym L. pomona, i zdorovykh vaktsinirovannykh liudei. SO - Zh Mikrobiol Epidemiol Immunobiol 1973 Aug;50(8):109-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 74077538 AU - Malakhov IuA AU - Polevodov NA AU - Teternik DM AU - Sosov RF AU - Cherevatenko LN TI - [Diagnosis of leptospirosis in slaughter animals] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 740308 DP - 1973 Aug IS - 0042-4846 TA - Veterinariia PG - 52-4 CY - USSR VI - 8 JC - XCC EM - 7404 PMID- 4771640 TT - Diagnostika leptospiroza u uboinykh zhivotnykh. SO - Veterinariia 1973 Aug;8:52-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 73242025 AU - Berman SJ AU - Tsai CC AU - Holmes K AU - Fresh JW AU - Watten RH TI - Sporadic anicteric leptospirosis in South Vietnam. A study in 150 patients. LA - Eng MH - Antibodies/analysis MH - Blood Sedimentation MH - Cerebrospinal Fluid Proteins/analysis MH - Conjunctivitis/etiology MH - Erythrocytes MH - Fever/etiology MH - Gastroenteritis/etiology MH - Human MH - Kidney Failure, Acute/complications MH - Leptospira/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/cerebrospinal fluid/complications/*diagnosis/drug therapy/immunology MH - Leukocyte Count MH - Male MH - Meningitis/complications MH - *Military Medicine MH - Muscular Diseases/etiology MH - Serotyping MH - Tetracycline/therapeutic use MH - United States MH - Vietnam PT - JOURNAL ARTICLE DA - 731028 DP - 1973 Aug IS - 0003-4819 TA - Ann Intern Med PG - 167-73 SB - A SB - M CY - UNITED STATES IP - 2 VI - 79 JC - 5A6 EM - 7312 PMID- 4726531 SO - Ann Intern Med 1973 Aug;79(2):167-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 73255990 AU - Limpias E AU - Marcus SJ TI - [Serological survey of leptospirosis in Santa Cruz, Bolivia] LA - Spa MH - Animal MH - Bolivia MH - Cattle MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 731115 DP - 1973 Aug IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 139-45 CY - UNITED STATES IP - 2 VI - 75 JC - AGG EM - 7312 PMID- 4269916 CU - 92 TT - Encuesta serologica de la leptospirosis en Santa Cruz, Bolivia. SO - Bol Oficina Sanit Panam 1973 Aug;75(2):139-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [24 medline neighbors] UI - 74309947 AU - Gratz NG TI - Urban rodent-borne disease and rodent distribution in Israel and nighboring countries. LA - Eng MH - Animal MH - DDT MH - Egypt MH - Human MH - Israel MH - Leptospira interrogans/isolation & purification MH - *Leptospirosis/epidemiology MH - *Plague/epidemiology MH - *Rats MH - Rickettsia typhi/isolation & purification MH - Rodent Control MH - Salmonella typhimurium/isolation & purification MH - Salmonella Infections/epidemiology MH - *Typhus, Endemic Flea-Borne/epidemiology MH - Urban Population MH - *Zoonoses PT - JOURNAL ARTICLE PT - REVIEW DA - 741118 DP - 1973 Aug IS - 0021-2180 TA - Isr J Med Sci PG - 969-79 SB - M CY - ISRAEL IP - 8 VI - 9 JC - GY0 EM - 7412 RF - 44 RO - O:47 RO - C:00 PMID- 4212502 CU - 91 SO - Isr J Med Sci 1973 Aug;9(8):969-79 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [79 medline neighbors] UI - 74168112 AU - Eichler W AU - Cerny V AU - Schiffel K TI - [Ornithonyssus bacoti mites as pest on a farm] LA - Ger MH - Animal MH - Coxiella MH - DDT MH - English Abstract MH - Francisella tularensis MH - Germany, East MH - Human MH - Infant MH - Insect Bites and Stings/epidemiology MH - Insect Control MH - Insect Vectors MH - Leptospira interrogans MH - Lindane MH - Mite Infestations/*epidemiology MH - Mites/anatomy & histology MH - *Rats MH - Rickettsia MH - Rodent Control MH - Rural Population MH - Yersinia pestis PT - JOURNAL ARTICLE DA - 740719 DP - 1973 Aug IS - 0003-3162 TA - Angew Parasitol PG - 169-76 SB - M CY - GERMANY, EAST IP - 3 VI - 14 JC - 4TJ EM - 7409 PMID- 4133599 CU - 95 TT - Milbenplage durch Ornithonyssus bacoti in einem Bauernhof. SO - Angew Parasitol 1973 Aug;14(3):169-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74049544 AU - Twigg GI AU - Hughes DM AU - McDiarmid A TI - The low incidence of leptospirosis in British deer. LA - Eng MH - Agglutination Tests MH - Animal MH - *Deer MH - Great Britain MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 740205 DP - 1973 Jul 28 IS - 0042-4900 TA - Vet Rec PG - 98-100 SB - M CY - ENGLAND IP - 4 VI - 93 JC - XBS EM - 7403 PMID- 4760935 CU - 88 SO - Vet Rec 1973 Jul 28;93(4):98-100 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74021976 AU - Ellis WA TI - Proceedings: Further studies on bovine leptospirosis in Scotland. LA - Eng MH - Abortion, Veterinary/epidemiology MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Female MH - Leptospirosis/epidemiology/*veterinary MH - Pregnancy MH - Scotland MH - Seasons PT - JOURNAL ARTICLE DA - 740105 DP - 1973 Jul 21 IS - 0042-4900 TA - Vet Rec PG - 78 SB - M CY - ENGLAND IP - 3 VI - 93 JC - XBS EM - 7402 PMID- 4795928 CU - 88 SO - Vet Rec 1973 Jul 21;93(3):78 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 73250914 AU - Gossler R AU - Hunermund G TI - [Serological studies on cattle in catchment area of Kabete (Kenia). 2. Determination of antibodies against Mycobacterium paratuberculosis, Brucella, Salmonella, Pasteurella multocida, Listeria and Leptospira] LA - Ger MH - Agglutination Tests MH - Animal MH - Antibodies/*analysis MH - Antibody Formation MH - Bacterial Infections/immunology/*veterinary MH - Brucella/immunology MH - Cattle MH - Cattle Diseases/*immunology MH - Complement Fixation Tests MH - English Abstract MH - Kenya MH - Leptospira/immunology MH - Listeria monocytogenes/immunology MH - Mycobacterium/immunology MH - Pasteurella/immunology MH - Salmonella/immunology PT - JOURNAL ARTICLE DA - 731112 DP - 1973 Jul 15 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 267-70 CY - GERMANY, WEST IP - 14 VI - 86 JC - 9Q8 EM - 7312 PMID- 4199742 CU - 91 TT - Serologische Untersuchungen bei Rindern im Einzugsgebiet von Kabete (Kenia). 2. Vorkommen von Antikorpern gegen Mycobacterium paratuberculosis, Brucellen, Salmonellen, Pasteurella multocida, Listerien und Leptospiren. SO - Berl Munch Tierarztl Wochenschr 1973 Jul 15;86(14):267-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 75004569 AU - Orlandella V AU - Ioli A AU - Alosi C AU - Sindoni L AU - Coppola L TI - [Research on the epidemiology-epizootology of leptospirosis. I. Serological studies on the role of the hedgehog, Erinaceus europaeus var. italicus Barrett-Hamilton, 1900, in the spread of pathogenic Leptospira] LA - Ita MH - Animal MH - Cattle MH - Cattle Diseases/*transmission MH - *Disease Reservoirs MH - Europe MH - *Hedgehogs MH - Italy MH - Leptospirosis/*transmission/veterinary MH - Sicily MH - Swine MH - Swine Diseases/*transmission MH - Zoonoses/*transmission PT - JOURNAL ARTICLE DA - 741218 DP - 1973 Jul-Dec IS - 0301-1453 TA - G Batteriol Virol Immunol [Microbiol] PG - 234-59 SB - M CY - ITALY IP - 7-12 VI - 66 JC - FAD EM - 7501 PMID- 4807679 CU - 85 TT - Ricerche sulla epidemio-epizootologia delle leptospirosi. I. Indagini sierologiche sul ruolo del riccio Erinaceus europaeus var. italicus Barrett-Hamilton, 1900, nella diffusione di leptospire patogene SO - G Batteriol Virol Immunol [Microbiol] 1973 Jul-Dec;66(7-12):234-59 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 76017921 AU - Santa Rosa CA AU - Filho OC AU - Pestana de Castro AF TI - [The authors examined 275 samples of kidneys from swines apparently healthy, slaughtered in an abbatoir at Sao Paulo (Brazil) (author's transl)] LA - Por MH - Animal MH - Brazil MH - Disease Reservoirs/*veterinary MH - English Abstract MH - Kidney/*microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Serodiagnosis MH - Swine/*microbiology PT - JOURNAL ARTICLE DA - 751126 DP - 1973 Jul-Sep IS - 0020-3653 TA - Arq Inst Biol (Sao Paulo) PG - 243-6 SB - M CY - BRAZIL IP - 3 VI - 40 JC - 8VF EM - 7601 PMID- 4806504 CU - 88 TT - Suinos como reservatorio de Leptospiras no Brasil EA - A SO - Arq Inst Biol (Sao Paulo) 1973 Jul-Sep;40(3):243-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 74271336 AU - Nicolescu M AU - Borsai L TI - [Production and use of an improved medium for preparation of leptospiral antigens] LA - Rum MH - Agglutination Tests MH - Animal MH - *Antigens, Bacterial MH - Complement Fixation Tests MH - *Culture Media MH - English Abstract MH - Human MH - Immune Sera MH - *Leptospira/immunology MH - Leptospirosis/diagnosis/immunology PT - JOURNAL ARTICLE DA - 740916 DP - 1973 Jul-Aug IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 365-70 CY - ROMANIA IP - 4 VI - 18 JC - MXQ EM - 7411 RO - O:00 RO - C:14 PMID- 4793223 TT - Cercetari privind elaborarea si folosirea in productie a unui mediu ameliorat pentru prepararea antigenelor de leptospire EA - A SO - Microbiol Parazitol Epidemiol (Bucur) 1973 Jul-Aug;18(4):365-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 74271333 AU - Dragomirescu M AU - Martincu V AU - Novac E TI - [Metabolic disorders in severe leptospirosis] LA - Rum MH - Acid-Base Equilibrium MH - Acidosis/etiology MH - English Abstract MH - Human MH - Hyperkalemia/etiology MH - Hyponatremia/etiology MH - Lactates/metabolism MH - Leptospirosis/*complications/metabolism MH - Metabolic Diseases/*etiology MH - Proteins/metabolism MH - Pyruvates/metabolism MH - Shock, Septic/etiology PT - JOURNAL ARTICLE DA - 740916 DP - 1973 Jul-Aug IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 351-4 CY - ROMANIA IP - 4 VI - 18 JC - MXQ EM - 7411 RO - O:00 RO - C:14 PMID- 4793220 TT - Tulburari metabolice in leptospirozele severe EA - A SO - Microbiol Parazitol Epidemiol (Bucur) 1973 Jul-Aug;18(4):351-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 74250974 AU - Mailloux M TI - [Beta-galactosidase activity in leptospires] LA - Fre MH - Colorimetry MH - Culture Media MH - English Abstract MH - Galactosidases/analysis/*isolation & purification MH - Leptospira/*enzymology PT - JOURNAL ARTICLE DA - 740820 DP - 1973 Jul IS - 0300-5410 TA - Ann Microbiol (Paris) PG - 119-20 CY - FRANCE IP - 1 VI - 124 JC - 5JY EM - 7410 RO - O:41 RO - C:15 PMID- 4791975 TT - Activite beta-galactosidasique chez les leptospires EA - A SO - Ann Microbiol (Paris) 1973 Jul;124(1):119-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 74035601 AU - Bazovska S AU - Hlavata Z TI - [Survival of Leptospira strains in the organism of experimental animals] LA - Slo MH - Animal MH - English Abstract MH - Guinea Pigs MH - Hamsters MH - Kidney/microbiology MH - Leptospira/*growth & development MH - Liver/microbiology MH - Spleen/microbiology MH - Time Factors PT - JOURNAL ARTICLE DA - 740119 DP - 1973 Jul IS - 0006-9248 TA - Bratisl Lek Listy PG - 33-7 CY - CZECHOSLOVAKIA IP - 1 VI - 60 JC - B5N EM - 7402 PMID- 4755248 CU - 90 TT - Prezivanie leptospirovych kmenov v organizme laboratornych zvierat. SO - Bratisl Lek Listy 1973 Jul;60(1):33-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 73211378 AU - Urquhart A AU - Grant L AU - Sulzer C TI - A new leptospiral serotype belonging to serogroup icterohaemorrhagiae. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial MH - Female MH - Kidney/microbiology MH - Leptospira canicola/immunology MH - Leptospira interrogans/classification/*immunology/isolation & purification MH - Rats PT - JOURNAL ARTICLE DA - 730906 DP - 1973 Jul IS - 0090-3558 TA - J Wildl Dis PG - 254-7 SB - M CY - UNITED STATES IP - 3 VI - 9 JC - KEM EM - 7310 PMID- 4716214 SO - J Wildl Dis 1973 Jul;9(3):254-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 73211368 AU - Tripathy DN AU - Hanson LE TI - Leptospires from water sources at Dixon Springs Agricultural Center. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial MH - Culture Media MH - Gerbillinae MH - Hamsters MH - Illinois MH - Leptospira/immunology/*isolation & purification MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 730906 DP - 1973 Jul IS - 0090-3558 TA - J Wildl Dis PG - 209-12 SB - M CY - UNITED STATES IP - 3 VI - 9 JC - KEM EM - 7310 PMID- 4716205 SO - J Wildl Dis 1973 Jul;9(3):209-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74148280 AU - Bondarenko BN TI - [Quantitative determination of lipids in thin-layer chromatography] LA - Rus MH - *Chromatography, Thin Layer MH - Densitometry MH - English Abstract MH - Indicators and Reagents MH - Iodine MH - Leptospira/analysis MH - Lipids/*analysis MH - Methods MH - Proteus mirabilis/analysis PT - JOURNAL ARTICLE DA - 740619 DP - 1973 Jul-Aug IS - 0042-8809 TA - Vopr Med Khim PG - 438-4 SB - M CY - USSR IP - 4 VI - 19 JC - XIQ EM - 7408 PMID- 4596134 CU - 90 TT - Kolichestvennoe opredelenie lipidov pri khromatografii v tonkikh sloiakh. SO - Vopr Med Khim 1973 Jul-Aug;19(4):438-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [92 medline neighbors] UI - 73242890 AU - Johnson RC AU - Walby J AU - Henry RA AU - Auran NE TI - Cultivation of parasitic leptospires: effect of pyruvate. LA - Eng MH - Animal MH - *Bacteriological Techniques MH - Culture Media MH - Hamsters MH - Leptospira/drug effects/*growth & development/pathogenicity MH - Leptospira canicola/drug effects/growth & development/pathogenicity MH - Lethal Dose 50 MH - Male MH - Pyruvates/*pharmacology MH - Serotyping MH - Serum Albumin, Bovine MH - Sodium MH - Species Specificity MH - Surface-Active Agents MH - Virulence PT - JOURNAL ARTICLE DA - 731030 DP - 1973 Jul IS - 0003-6919 TA - Appl Microbiol PG - 118-9 SB - M CY - UNITED STATES IP - 1 VI - 26 JC - 6K0 EM - 7312 PMID- 4580191 CU - 90 SO - Appl Microbiol 1973 Jul;26(1):118-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [25 medline neighbors] UI - 74005449 AU - Oana C AU - Micu I AU - Manta I AU - Ioan E AU - Secu A AU - Birzu N AU - Butuc A TI - [Epidemics of leptospirosis and ornithosis in unusual epidemiological conditions] LA - Rum MH - Adenoviridae Infections/*complications MH - Adolescence MH - Adult MH - Animal MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Ornithosis/*epidemiology MH - Romania MH - Typhoid/*complications MH - *Zoonoses PT - JOURNAL ARTICLE DA - 731212 DP - 1973 Jul-Sep IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 519-22 CY - ROMANIA IP - 3 VI - 77 JC - SHP EM - 7401 PMID- 4355107 CU - 93 TT - Epidemii de leptospiroza si ornitoza in contexte epidemiologice particulare. SO - Rev Med Chir Soc Med Nat Iasi 1973 Jul-Sep;77(3):519-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74040961 AU - Bolotskii IA AU - Sidnevets PV AU - Khitsunov LL TI - [Epizootology of leptospirosis] LA - Rus MH - Animal MH - Cattle MH - Dogs MH - Horses MH - Leptospirosis/epidemiology/microbiology/*veterinary MH - Rodentia MH - Russia MH - Serotyping MH - Sheep MH - Swine PT - JOURNAL ARTICLE DA - 740124 DP - 1973 Jul IS - 0042-4846 TA - Veterinariia PG - 46-7 CY - USSR VI - 7 JC - XCC EM - 7403 PMID- 4271210 CU - 92 TT - K epizootologii leptospiroza. SO - Veterinariia 1973 Jul;7:46-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [65 medline neighbors] UI - 74021303 AU - Ladds PW AU - Dennett DP AU - Glazebrook JS TI - A survey of the genitalia of bulls in Northern Australia. LA - Eng MH - Age Factors MH - Animal MH - Antibodies, Bacterial MH - Antibodies, Viral MH - Australia MH - Brucella abortus/immunology MH - Campylobacter fetus/isolation & purification MH - Cattle MH - Cattle Diseases/*epidemiology/pathology MH - Epididymis/pathology MH - Genital Diseases, Male/epidemiology/pathology/*veterinary MH - Hemagglutination Tests MH - Infectious Bovine Rhinotracheitis/immunology/isolation & purification MH - Leptospira/immunology MH - Male MH - Penis/microbiology MH - Testis/pathology MH - Trichomonas/isolation & purification PT - JOURNAL ARTICLE DA - 740105 DP - 1973 Jul IS - 0005-0423 TA - Aust Vet J PG - 335-40 SB - M CY - AUSTRALIA IP - 7 VI - 49 JC - 9IE EM - 7402 PMID- 4201233 CU - 91 SO - Aust Vet J 1973 Jul;49(7):335-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 73252840 AU - De Martino C AU - Accinni L AU - Procicchiani G TI - Ultrastructural study on contractile structures in mammalian nephron. Their development in the metanephros of human embryo. LA - Eng MH - Animal MH - Capillaries MH - Cell Membrane MH - Cell Nucleus MH - Dogs MH - Endoplasmic Reticulum MH - Epithelium/cytology MH - Glomerular Filtration Rate MH - Glomerulonephritis/pathology MH - Glycogen MH - Goodpasture's Syndrome/pathology MH - Haplorhini MH - Human MH - Kidney/*cytology/embryology/pathology MH - Kidney Glomerulus/blood supply MH - Leptospirosis/pathology MH - Lysosomes MH - Mice MH - Mice, Inbred NZB MH - Microscopy, Electron MH - Muscle, Smooth/cytology MH - Nephritis/pathology MH - Nephrons/cytology MH - Rats PT - JOURNAL ARTICLE DA - 731112 DP - 1973 Jun 20 TA - Z Zellforsch Mikrosk Anat PG - 101-24 SB - M CY - GERMANY, WEST IP - 1 VI - 140 JC - Y30 EM - 7312 PMID- 4199850 CU - 91 SO - Z Zellforsch Mikrosk Anat 1973 Jun 20;140(1):101-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75161386 AU - Kinebuchi H AU - Afoakwa SN TI - Leptospirosis in Ghana. LA - Eng MH - Agglutination Tests MH - Diagnosis, Differential MH - Ghana MH - Hepatitis A/diagnosis MH - Human MH - Jaundice/diagnosis MH - Leptospirosis/diagnosis/*epidemiology/immunology/microbiology PT - JOURNAL ARTICLE DA - 750804 DP - 1973 Jun IS - 0016-9560 TA - Ghana Med J PG - 190-3 CY - GHANA IP - 2 VI - 12 JC - YEC EM - 7509 PMID- 4805646 CU - 88 SO - Ghana Med J 1973 Jun;12(2):190-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 74045980 AU - Matsui H AU - Ashizawa Y AU - Imamura S TI - [Evaluation of the indirect hemagglutination test for human leptospirosis (author's transl)] LA - Jpn MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - English Abstract MH - Evaluation Studies MH - *Hemagglutination Tests MH - Human MH - Leptospirosis/*diagnosis MH - Middle Age PT - JOURNAL ARTICLE DA - 740131 DP - 1973 Jun IS - 0021-5082 TA - Nippon Eiseigaku Zasshi PG - 237-42 CY - JAPAN IP - 2 VI - 28 JC - KKN EM - 7403 PMID- 4796674 CU - 85 SO - Nippon Eiseigaku Zasshi 1973 Jun;28(2):237-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 74109023 AU - Rostomian SV TI - [A method of detecting leptospira in the water of open reservoirs] LA - Rus MH - Leptospira/*isolation & purification MH - Methods MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 740425 DP - 1973 Jun TA - Zh Mikrobiol Epidemiol Immunobiol PG - 118-9 SB - M CY - USSR IP - 6 VI - 50 JC - Y9O EM - 7406 PMID- 4780903 CU - 90 TT - Metod vyiavleniia leptospir v vode otkrytykh vodoemov. SO - Zh Mikrobiol Epidemiol Immunobiol 1973 Jun;50(6):118-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 74069758 AU - Gunnarsson A AU - Hurvell B AU - Hanko E TI - Proceedings: Netherlands Society for Microbiology meeting at Utrecht on 2 May 1973. Environmental effects on bacterial wall synthesis. LA - Swe MH - Animal MH - Antibodies, Bacterial MH - Dog Diseases/diagnosis/*microbiology/pathology MH - Dogs MH - English Abstract MH - Guinea Pigs MH - Hemagglutination Tests MH - Immune Sera MH - Kidney Cortex/pathology MH - Leptospira canicola/immunology/*isolation & purification MH - Leptospirosis/diagnosis/microbiology/*veterinary MH - Nephritis/diagnosis/microbiology/pathology/*veterinary MH - Quarantine MH - Rabbits/immunology MH - Sweden MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 740302 DP - 1973 Jun IS - 0029-1579 TA - Nord Vet Med PG - 313-21 SB - M CY - DENMARK IP - 6 VI - 25 JC - O4Z EM - 7404 PMID- 4768223 TT - Isolering av Leptospira canicola fran hund. SO - Nord Vet Med 1973 Jun;25(6):313-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73212993 AU - Cole JR Jr AU - Sulzer CR AU - Pursell AR TI - Improved microtechnique for the leptospiral microscopic agglutination test. LA - Eng MH - *Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial MH - Comparative Study MH - Diagnosis, Differential MH - Evaluation Studies MH - Human MH - Immune Sera MH - Leptospira/*immunology MH - Leptospirosis/blood/*diagnosis MH - Methods MH - Rabbits/immunology PT - JOURNAL ARTICLE DA - 730912 DP - 1973 Jun IS - 0003-6919 TA - Appl Microbiol PG - 976-80 SB - M CY - UNITED STATES IP - 6 VI - 25 JC - 6K0 EM - 7310 PMID- 4736794 CU - 90 SO - Appl Microbiol 1973 Jun;25(6):976-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73253659 AU - Parry WH AU - Seymour MW TI - An unusual case of leptospirosis. LA - Eng MH - Animal MH - Bacteriuria MH - *Bites and Stings MH - Disease Vectors MH - Dogs MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis MH - Male MH - Middle Age MH - Public Health MH - Rats MH - Rodent Control PT - JOURNAL ARTICLE DA - 731113 DP - 1973 Jun IS - 0032-6518 TA - Practitioner PG - 791-3 SB - M CY - ENGLAND IP - 260 VI - 210 JC - PHQ EM - 7312 PMID- 4731060 SO - Practitioner 1973 Jun;210(260):791-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 73212258 AU - Staneck JL AU - Henneberry RC AU - Cox CD TI - Growth requirements of pathogenic Leptospira. LA - Eng MH - Acetates/pharmacology MH - Animal MH - Biotin/pharmacology MH - Chromatography MH - *Culture Media MH - Fatty Acids, Nonesterified/toxicity MH - Hamsters MH - Iron/pharmacology MH - Leptospira/drug effects/*growth & development/metabolism/pathogenicity MH - Magnesium/pharmacology MH - Potassium/pharmacology MH - Serum Albumin, Bovine MH - Virulence PT - JOURNAL ARTICLE DA - 730910 DP - 1973 Jun IS - 0019-9567 TA - Infect Immun PG - 886-97 SB - M CY - UNITED STATES IP - 6 VI - 7 JC - GO7 EM - 7310 PMID- 4716547 SO - Infect Immun 1973 Jun;7(6):886-97 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 73191265 AU - Friedmann CT AU - Spiegel EL AU - Aaron E AU - McIntyre R TI - Leptospirosis ballum contracted from pet mice. LA - Eng MH - Adult MH - Animal MH - Blood/microbiology MH - Epidemiologic Methods MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*etiology MH - Male MH - Mice MH - Rodent Diseases/*microbiology MH - Zoonoses/*microbiology PT - JOURNAL ARTICLE DA - 730807 DP - 1973 Jun IS - 0008-1264 TA - Calif Med PG - 51-2 CY - UNITED STATES IP - 6 VI - 118 JC - CFU EM - 7309 PMID- 4709528 SO - Calif Med 1973 Jun;118(6):51-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [62 medline neighbors] UI - 74286944 AU - Chiba K TI - Purification and lyophylization of Weil's disease therapeutic serum. LA - Eng MH - Agglutination MH - Animal MH - Guinea Pigs MH - IgG/isolation & purification MH - IgM MH - *Immunization, Passive MH - Immunoelectrophoresis MH - Immunoglobulin Fragments/isolation & purification MH - Immunoglobulins/*isolation & purification MH - Leptospira interrogans/immunology MH - Pepsin A/therapeutic use MH - Rabbits MH - Weil's Disease/*therapy PT - JOURNAL ARTICLE DA - 741010 DP - 1973 Jun IS - 0023-1924 TA - Kitasato Arch Exp Med PG - 57-71 CY - JAPAN IP - 1 VI - 46 JC - KVS EM - 7411 RO - O:32 RO - C:09 PMID- 4602932 CU - 90 SO - Kitasato Arch Exp Med 1973 Jun;46(1):57-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74025162 AU - Nicolescu M AU - Borsai L AU - Alamita I TI - Leptospirosis in albino rats. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals, Laboratory MH - Antibodies, Bacterial/analysis MH - Autopsy MH - Fluorescent Antibody Technique MH - Guinea Pigs MH - Human MH - Immune Sera MH - Leptospira interrogans/immunology MH - Leptospirosis/etiology/immunology/*veterinary MH - *Rats MH - Serotyping PT - JOURNAL ARTICLE DA - 740111 DP - 1973 Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 171-7 CY - ROMANIA IP - 2 VI - 32 JC - 8EM EM - 7402 PMID- 4584313 CU - 90 SO - Arch Roum Pathol Exp Microbiol 1973 Jun;32(2):171-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 74012331 AU - Reasoner DJ TI - Microbiology--detection of bacterial pathogens and their occurrence. LA - Eng MH - Animal MH - Animal Feed MH - Antibiotics/therapeutic use MH - Bacteria/*isolation & purification MH - Bacterial Infections/*microbiology/veterinary MH - Bacteriological Techniques MH - Bird Diseases/microbiology MH - Cattle MH - Cattle Diseases/microbiology MH - Disease Reservoirs/veterinary MH - Drug Resistance, Microbial MH - Dysentery, Bacillary/microbiology MH - Escherichia coli Infections/microbiology MH - Gastrointestinal Diseases/microbiology MH - Horse Diseases/microbiology MH - Horses MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/microbiology MH - Rodent Diseases/microbiology MH - Salmonella/isolation & purification MH - Salmonella Food Poisoning/microbiology MH - Salmonella Infections/microbiology MH - Salmonella Infections, Animal/microbiology MH - Sheep MH - Sheep Diseases/microbiology MH - Shigella/isolation & purification MH - Swine MH - Swine Diseases/microbiology PT - JOURNAL ARTICLE PT - REVIEW DA - 731216 DP - 1973 Jun IS - 0043-1303 TA - J Water Pollut Control Fed PG - 1278-89 CY - UNITED STATES IP - 6 VI - 45 JC - KDZ EM - 7401 RF - 105 PMID- 4583383 CU - 90 SO - J Water Pollut Control Fed 1973 Jun;45(6):1278-89 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [98 medline neighbors] UI - 73258682 AU - O'Connor GR TI - The uvea. LA - Eng MH - Adult MH - Aged MH - Child MH - Coccidiosis MH - Escherichia coli Infections MH - Eye Neoplasms MH - Female MH - Histoplasmosis MH - Human MH - Infant MH - Leiomyosarcoma MH - Leptospirosis MH - Male MH - Melanoma MH - Proteus Infections MH - Retinoblastoma MH - Rhabdomyoma MH - Streptococcal Infections MH - Toxoplasmosis, Ocular MH - Treponema pallidum MH - Treponemal Infections MH - *Uvea/anatomy & histology MH - Uveitis/*etiology MH - Xanthomatosis PT - JOURNAL ARTICLE PT - REVIEW DA - 731116 DP - 1973 Jun IS - 0003-9950 TA - Arch Ophthalmol PG - 505-17 SB - A SB - M CY - UNITED STATES IP - 6 VI - 89 JC - 830 EM - 7312 RF - 143 PMID- 4581780 CU - 90 SO - Arch Ophthalmol 1973 Jun;89(6):505-17 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 73244760 AU - Hodges RT AU - Ekdahl MO TI - Use of a fluorescent antibody technique for the serological differentiation of leptospiral serotypes in cultures and in bovine urine. LA - Eng MH - Animal MH - Antibody Specificity MH - Bacteriuria/diagnosis/*veterinary MH - Cattle MH - Cattle Diseases/*diagnosis MH - Cross Reactions MH - Female MH - Fluorescent Antibody Technique MH - Leptospirosis/diagnosis/*veterinary MH - Rabbits/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 731101 DP - 1973 Jun IS - 0048-0169 TA - N Z Vet J PG - 109-15 CY - NEW ZEALAND IP - 6 VI - 21 JC - OBZ EM - 7312 PMID- 4580414 CU - 90 SO - N Z Vet J 1973 Jun;21(6):109-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 74025804 AU - Tan DS TI - Occupational distribution of leptospiral (SEL) antibodies in West Malaysia. LA - Eng MH - Adult MH - Antibodies/*analysis MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Occupational Diseases/*epidemiology MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 740111 DP - 1973 Jun IS - 0300-5283 TA - Med J Malaya PG - 253-7 CY - MALAYSIA IP - 4 VI - 27 JC - M2M EM - 7402 PMID- 4270781 CU - 92 SO - Med J Malaya 1973 Jun;27(4):253-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 74012330 AU - Craun GF TI - Microbiology--waterborne outbreaks. LA - Eng MH - Animal MH - Balantidiasis/etiology MH - Cholera/etiology MH - Disease Outbreaks/*epidemiology MH - Disease Reservoirs MH - Disease Vectors MH - Dracunculiasis/etiology MH - Dysentery, Bacillary/etiology MH - Food Poisoning/etiology MH - Gastroenteritis/etiology MH - Hepatitis A/etiology MH - Human MH - Leptospirosis/etiology MH - Meningoencephalitis/etiology MH - Paratyphoid Fever/etiology MH - Salmonella Infections/etiology MH - Salmonella Infections, Animal/complications MH - Schistosomiasis/etiology MH - Sewage MH - Snails MH - Turtles MH - Typhoid/etiology MH - *Water Microbiology MH - *Water Pollution MH - Water Supply PT - JOURNAL ARTICLE DA - 731216 DP - 1973 Jun IS - 0043-1303 TA - J Water Pollut Control Fed PG - 1265-77 CY - UNITED STATES IP - 6 VI - 45 JC - KDZ EM - 7401 PMID- 4270475 CU - 92 SO - J Water Pollut Control Fed 1973 Jun;45(6):1265-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 73223740 AU - Darnell A AU - Rodes J AU - Oliver JA AU - Bruguera M AU - Revert L TI - [Icterohemorrhagic leptospirosis without fever] LA - Spa MH - Fever MH - Human MH - Male MH - Middle Age MH - *Weil's Disease PT - JOURNAL ARTICLE DA - 730926 DP - 1973 May 31 IS - 0014-2565 TA - Rev Clin Esp PG - 389-92 CY - SPAIN IP - 4 VI - 129 JC - RNL EM - 7311 PMID- 4720285 TT - Leptospirosis icterohemorragia de presentacion afebril. SO - Rev Clin Esp 1973 May 31;129(4):389-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 73190894 AU - Cybulska M AU - Dolezko-Marciniak H AU - Hencner Z TI - [Serologic studies in leptospira infections in humans in the Lublin Province in the years 1966-1971] LA - Pol MH - Agglutination Tests MH - Antigens MH - English Abstract MH - Human MH - Leptospira/immunology MH - Poland MH - *Weil's Disease/diagnosis/epidemiology/immunology PT - JOURNAL ARTICLE DA - 730806 DP - 1973 May 14 IS - 0032-3756 TA - Pol Tyg Lek PG - 733-5 CY - POLAND IP - 20 VI - 28 JC - PBY EM - 7309 PMID- 4709394 CU - 88 TT - Badania serologiczne w kierunku zakazen leptospirozami u ludzi w woj. lubelskim w latach 1966-1971. SO - Pol Tyg Lek 1973 May 14;28(20):733-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74069969 AU - Kambaratov PI TI - [Diagnosis of Q fever (Q fever, brucellosis, hemorrhagic fever with renal syndrome and leptospirosis)] LA - Rus MH - Acute Disease MH - Adolescence MH - Adult MH - Aged MH - Brucellosis/*diagnosis MH - Comparative Study MH - Diagnosis, Differential MH - English Abstract MH - Female MH - Hemorrhagic Fevers, Viral/*diagnosis MH - Human MH - Kidney Diseases/*diagnosis MH - Leptospirosis/*diagnosis MH - Male MH - Middle Age MH - Q Fever/*diagnosis MH - Seasons MH - Syndrome PT - JOURNAL ARTICLE DA - 740302 DP - 1973 May IS - 0038-5077 TA - Sov Med PG - 59-63 CY - USSR IP - 5 VI - 36 JC - UW7 EM - 7404 PMID- 4768347 CU - 90 TT - Raspoznavanie ku-likhoradki (ku-likhoradka, brutselloz, gemorragicheskaia likhoradka s pochechnym sindromom, leptospiroz. SO - Sov Med 1973 May;36(5):59-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 74026909 AU - Walters JH TI - Systemic infections and the liver. LA - Eng MH - Granuloma/etiology MH - Human MH - Leptospirosis/complications MH - Liver Diseases/*etiology MH - Parasitic Diseases/complications MH - Relapsing Fever/complications MH - Yellow Fever/complications PT - JOURNAL ARTICLE DA - 740114 DP - 1973 May IS - 0032-6518 TA - Practitioner PG - 618-25 SB - M CY - ENGLAND IP - 259 VI - 210 JC - PHQ EM - 7402 PMID- 4751008 SO - Practitioner 1973 May;210(259):618-25 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 74001941 AU - Pavlow P AU - Dumanov Y AU - Denev Y AU - Kolev M AU - Stoyanova R AU - Loseva T AU - Djankov I TI - A study of parasite-host immunological interrelations. IV. Investigation of the protein profiles in lambs, cats and birds in experimental spirochetosis and leptospirosis. LA - Eng MH - Animal MH - Blood Protein Electrophoresis MH - Blood Proteins/analysis MH - Cat Diseases/*blood MH - Cats MH - Disease Models, Animal MH - Female MH - Leptospirosis/blood/*veterinary MH - Male MH - Poultry MH - Poultry Diseases/*blood MH - Sheep MH - Sheep Diseases/*blood MH - Spirochaetales Infections/blood/*veterinary PT - JOURNAL ARTICLE DA - 731130 DP - 1973 May TA - Zentralbl Veterinarmed [B] PG - 230-40 CY - GERMANY, WEST IP - 3 VI - 20 JC - Y72 EM - 7401 PMID- 4734054 CU - 89 SO - Zentralbl Veterinarmed [B] 1973 May;20(3):230-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 73209875 AU - Myers DM AU - Varela-Diaz VM TI - Selective isolation of leptospiras from contaminated material by incorporation of neomycin to culture media. LA - Eng MH - Animal MH - Culture Media MH - Fluorouracil/pharmacology MH - Food Microbiology MH - Hamsters MH - Kidney/microbiology MH - Leptospira/drug effects/growth & development/*isolation & purification MH - Leptospirosis/microbiology MH - Liver/microbiology MH - Meat MH - Neomycin/*pharmacology MH - Serotyping MH - Swine MH - Time Factors PT - JOURNAL ARTICLE DA - 730906 DP - 1973 May IS - 0003-6919 TA - Appl Microbiol PG - 781-6 SB - M CY - UNITED STATES IP - 5 VI - 25 JC - 6K0 EM - 7310 PMID- 4715558 CU - 90 SO - Appl Microbiol 1973 May;25(5):781-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 73174976 AU - Finn MA AU - Jenkin HM TI - Cytopathic effects of Leptospira serotypes patoc and canicola in three kidney cell culture systems. LA - Eng MH - Animal MH - Cell Count MH - Cells, Cultured MH - Culture Media MH - Hamsters MH - Haplorhini MH - Kidney MH - Leptospira/cytology/*growth & development MH - Leptospira canicola/cytology/growth & development MH - Methods MH - Swine PT - JOURNAL ARTICLE DA - 730709 DP - 1973 May IS - 0002-9645 TA - Am J Vet Res PG - 669-72 SB - M CY - UNITED STATES IP - 5 VI - 34 JC - 40C EM - 7308 PMID- 4634065 CU - 91 SO - Am J Vet Res 1973 May;34(5):669-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 73169109 AU - Bain BJ AU - Ribush NT AU - Nicoll P AU - Whitsed HM AU - Morgan TO TI - Renal failure and transient paraproteinemia due to Leptospira pomona. Case reports and literature review. LA - Eng MH - Adult MH - Anuria/etiology MH - Biopsy MH - Blood Protein Disorders/*etiology MH - Female MH - Human MH - IgM/analysis MH - Immunoelectrophoresis MH - Kidney Failure, Acute/blood/*etiology/pathology/radiography/urine MH - Leptospira/pathogenicity MH - Leptospirosis/*complications MH - Male MH - *Serum Globulins MH - Urography PT - JOURNAL ARTICLE PT - REVIEW DA - 730629 DP - 1973 May IS - 0003-9926 TA - Arch Intern Med PG - 740-5 SB - A SB - M CY - UNITED STATES IP - 5 VI - 131 JC - 7FS EM - 7308 RF - 45 PMID- 4573664 CU - 90 SO - Arch Intern Med 1973 May;131(5):740-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 74090963 AU - Babudieri B AU - Castelli M AU - Pisoni F TI - Comparative tests with formolized and irradiated vaccines against leptospirosis. LA - Eng MH - Animal MH - Bacterial Vaccines/radiation effects/*standards MH - Comparative Study MH - Formaldehyde/pharmacology MH - Guinea Pigs MH - Leptospira/drug effects/*immunology/radiation effects MH - Leptospirosis/*prevention & control MH - Radiation Effects MH - *Vaccination MH - Vaccines, Attenuated/*standards MH - Virulence PT - JOURNAL ARTICLE DA - 740402 DP - 1973 May IS - 0042-9686 TA - Bull World Health Organ PG - 587-90 CY - SWITZERLAND IP - 5 VI - 48 JC - C80 EM - 7405 PMID- 4544147 CU - 89 SO - Bull World Health Organ 1973 May;48(5):587-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 73216099 AU - Rehka V AU - Rachunkova A TI - [Human parasitic diseases in East Moravia] LA - Ger MH - Adolescence MH - Adult MH - Aged MH - Ancylostomiasis/epidemiology MH - Cestoda MH - Cestode Infections/epidemiology MH - Child MH - Child, Preschool MH - Czechoslovakia MH - English Abstract MH - Enterobius MH - Feces/analysis MH - Female MH - Human MH - Infant MH - Leptospira interrogans MH - Leptospirosis/epidemiology MH - Loa MH - Male MH - Middle Age MH - Nematode Infections/epidemiology MH - Parasitic Diseases/*epidemiology MH - Protozoan Infections/epidemiology MH - Trichomonas vaginalis MH - Trichuroidea MH - Vaginal Smears PT - JOURNAL ARTICLE DA - 730913 DP - 1973 May IS - 0003-3162 TA - Angew Parasitol PG - 101-15 SB - M CY - GERMANY, EAST IP - 2 VI - 14 JC - 4TJ EM - 7310 PMID- 4541548 CU - 89 TT - Humanparasitosen in Ostmahern. SO - Angew Parasitol 1973 May;14(2):101-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 73202968 AU - Cervova H TI - [Leptospiroses in the preventive and clinical material of the parasitological laboratory of the Hygienic station at the Pragne National Committee] LA - Cze MH - Animal MH - Cattle MH - Czechoslovakia MH - Disease Reservoirs MH - Disease Vectors MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Mice MH - *Outpatient Clinics, Hospital MH - Rats MH - Sheep MH - Swine PT - JOURNAL ARTICLE DA - 730822 DP - 1973 May IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 126-40 CY - CZECHOSLOVAKIA IP - 3 VI - 22 JC - CSH EM - 7310 PMID- 4268250 CU - 92 TT - Leptospirozy v preventiveim a klinickem matterialu parazitologickeho pracoviste HS NV. SO - Cesk Epidemiol Mikrobiol Imunol 1973 May;22(3):126-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73187357 AU - Ellis HR TI - Leptospirosis in Arkansas 1972. LA - Eng MH - Animal MH - Animal Diseases/epidemiology MH - Arkansas MH - Human MH - Leptospirosis/*epidemiology MH - Time Factors MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 730802 DP - 1973 May IS - 0004-1858 TA - J Ark Med Soc PG - 393-4 CY - UNITED STATES IP - 12 VI - 69 JC - HEV EM - 7309 PMID- 4267697 CU - 92 SO - J Ark Med Soc 1973 May;69(12):393-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 73170697 AU - Babudieri B AU - D'Aquino A TI - Systematics of leptospirae strains isolated in the Sepik District, Papua New Guinea. LA - Eng MH - Animal MH - Dogs MH - Leptospira/*classification/isolation & purification MH - Marsupialia MH - New Guinea MH - Serotyping PT - JOURNAL ARTICLE DA - 730702 DP - 1973 Apr 7 IS - 0025-729X TA - Med J Aust PG - 701 SB - M CY - AUSTRALIA IP - 14 VI - 1 JC - M26 EM - 7308 PMID- 4701864 SO - Med J Aust 1973 Apr 7;1(14):701 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75179528 AU - Sosov RF TI - [Immunizing leptospiral subinfection] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology/immunology MH - Female MH - Leptospirosis/immunology/*veterinary MH - USSR PT - JOURNAL ARTICLE DA - 750820 DP - 1973 Apr IS - 0042-4846 TA - Veterinariia PG - 39-41 CY - USSR IP - 4 JC - XCC EM - 7510 PMID- 4805777 CU - 88 TT - Ob immuniziruiushchei leptospiroznoi subinfektsii SO - Veterinariia 1973 Apr;(4):39-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73163151 AU - Baker LA AU - Cox CD TI - Quantitative assay for genus-specific leptospiral antigen and antibody. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Antigens, Bacterial/*analysis MH - Diagnosis, Differential MH - Erythrocytes/immunology MH - *Hemagglutination Inhibition Tests MH - *Hemagglutination Tests MH - Human MH - Immune Sera MH - Leptospira/*immunology MH - Leptospirosis/diagnosis MH - Methods MH - Rabbits/immunology MH - Sheep/immunology PT - JOURNAL ARTICLE DA - 730621 DP - 1973 Apr IS - 0003-6919 TA - Appl Microbiol PG - 697-8 SB - M CY - UNITED STATES IP - 4 VI - 25 JC - 6K0 EM - 7308 PMID- 4735489 CU - 90 SO - Appl Microbiol 1973 Apr;25(4):697-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 73163115 AU - Myers DM AU - Varela-Diaz VM AU - Siniuk AA TI - Long-term survival of Leptospira in a biphasic culture medium containing charcoal. LA - Eng MH - Animal MH - Cell Survival MH - Charcoal MH - *Culture Media MH - Immune Sera MH - Leptospira/*growth & development MH - Rabbits/immunology MH - Serotyping MH - Time Factors PT - JOURNAL ARTICLE DA - 730621 DP - 1973 Apr IS - 0003-6919 TA - Appl Microbiol PG - 514-6 SB - M CY - UNITED STATES IP - 4 VI - 25 JC - 6K0 EM - 7308 PMID- 4735486 CU - 90 SO - Appl Microbiol 1973 Apr;25(4):514-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 73175303 AU - Hubbert WT AU - Booth GD AU - Bolton WD AU - Dunne HW AU - McEntee K AU - Smith RE AU - Tourtellotte ME TI - Bovine abortions in five Northeastern states, 1960-1970: evaluation of diagnostic laboratory data. LA - Eng MH - Abortion, Veterinary/*epidemiology/etiology MH - Animal MH - Aspergillosis/epidemiology/veterinary MH - Cattle MH - Cattle Diseases/*epidemiology/etiology MH - Corynebacterium Infections/epidemiology/veterinary MH - Female MH - Infectious Bovine Rhinotracheitis/epidemiology MH - Leptospirosis/epidemiology/veterinary MH - Male MH - Pregnancy MH - Seasons MH - Streptococcal Infections/epidemiology/veterinary MH - United States MH - Vibrio Infections/epidemiology/veterinary PT - JOURNAL ARTICLE DA - 730709 DP - 1973 Apr IS - 0010-8901 TA - Cornell Vet PG - 291-316 SB - M CY - UNITED STATES IP - 2 VI - 63 JC - DRI EM - 7308 PMID- 4703675 CU - 90 SO - Cornell Vet 1973 Apr;63(2):291-316 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 73146371 AU - Tripathy DN AU - Hanson LE TI - Studies of Leptospira illini, strain 3055: pathogenicity for different animals. LA - Eng MH - Agglutination Tests MH - Animal MH - *Animals, Laboratory MH - Cattle MH - Cattle Diseases/*etiology/immunology MH - Chick Embryo MH - Chickens MH - Ethionine/pharmacology MH - Female MH - Gerbillinae MH - Guinea Pigs MH - Hamsters MH - Injections, Intraperitoneal MH - Kidney/microbiology MH - Leptospira/isolation & purification/*pathogenicity MH - Leptospirosis/etiology/immunology/*veterinary MH - Male MH - Methotrexate/pharmacology MH - Mice MH - Pregnancy MH - Splenectomy PT - JOURNAL ARTICLE DA - 730523 DP - 1973 Apr IS - 0002-9645 TA - Am J Vet Res PG - 557-62 SB - M CY - UNITED STATES IP - 4 VI - 34 JC - 40C EM - 7307 PMID- 4693813 SO - Am J Vet Res 1973 Apr;34(4):557-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 73143723 AU - Kirkbride CA AU - Bicknell EJ AU - Reed DE AU - Robl MG AU - Knudtson WU AU - Wohlgemuth K TI - A diagnostic survey of bovine abortion and stillbirth in the Northern Plains States. LA - Eng MH - Abortion, Veterinary/*diagnosis/etiology MH - Animal MH - Bacterial Infections/diagnosis/veterinary MH - Bovine Virus Diarrhea-Mucosal Disease/diagnosis MH - Brucellosis, Bovine/diagnosis MH - Cattle MH - Cattle Diseases/*diagnosis/etiology MH - Corynebacterium Infections/veterinary MH - Dystocia/veterinary MH - Female MH - Fetal Death/diagnosis/etiology/*veterinary MH - Infectious Bovine Rhinotracheitis/diagnosis MH - Leptospirosis/diagnosis/veterinary MH - Listeria Infections/diagnosis/veterinary MH - Mycoses/diagnosis/veterinary MH - Pregnancy MH - Vibrio Infections/diagnosis/veterinary PT - JOURNAL ARTICLE DA - 730518 DP - 1973 Apr 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 556-60 SB - M CY - UNITED STATES IP - 7 VI - 162 JC - HAV EM - 7307 PMID- 4692821 CU - 90 SO - J Am Vet Med Assoc 1973 Apr 1;162(7):556-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 73146372 AU - Tripathy DN AU - Hanson LE TI - Studies of Leptospira illini, strain 3055: immunologic and serologic determinations. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/isolation & purification MH - Cattle MH - Cattle Diseases/*immunology MH - Erythrocytes/immunology MH - Hemagglutination Tests MH - Immunodiffusion MH - Leptospira/immunology MH - Leptospirosis/immunology/*veterinary MH - Rabbits/immunology MH - Swine MH - Swine Diseases/*immunology PT - JOURNAL ARTICLE DA - 730523 DP - 1973 Apr IS - 0002-9645 TA - Am J Vet Res PG - 563-5 SB - M CY - UNITED STATES IP - 4 VI - 34 JC - 40C EM - 7307 PMID- 4632748 CU - 91 SO - Am J Vet Res 1973 Apr;34(4):563-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 73169437 AU - Schubert JH AU - Sulzer CR TI - Maintenance of leptospira by storage at -75 C. LA - Eng MH - Bacteriological Techniques MH - *Freeze Drying MH - *Leptospira canicola MH - *Leptospira interrogans MH - *Preservation, Biological PT - JOURNAL ARTICLE DA - 730629 DP - 1973 Apr IS - 0017-9035 TA - Health Lab Sci PG - 96-101 SB - M CY - UNITED STATES IP - 2 VI - 10 JC - G2C EM - 7308 PMID- 4573683 CU - 90 SO - Health Lab Sci 1973 Apr;10(2):96-101 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 73143414 AU - Turner LH TI - Leptospirosis. LA - Eng MH - Acute Disease MH - Agriculture MH - Animal MH - Human MH - Leptospira/pathogenicity MH - *Leptospirosis/blood/cerebrospinal fluid/diagnosis/drug therapy/immunology/microbiology/therapy/urine MH - Occupational Diseases MH - Penicillins/therapeutic use MH - Septicemia MH - Serodiagnosis MH - Zoonoses PT - JOURNAL ARTICLE DA - 730518 DP - 1973 Mar 3 IS - 0007-1447 TA - Br Med J PG - 537-40 SB - A SB - M CY - ENGLAND IP - 852 VI - 1 JC - B4W EM - 7307 PMID- 4734999 CU - 85 SO - Br Med J 1973 Mar 3;1(852):537-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 74266071 AU - Mailloux M TI - [A case of human leptospirosis in Saint-Laurent-du-Maroni (French Guiana)] LA - Fre MH - Adult MH - Diagnosis, Differential MH - English Abstract MH - French Guiana MH - Human MH - Leptospira interrogans/*isolation & purification MH - Male MH - Serodiagnosis MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 740823 DP - 1973 Mar-Apr IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 269-72 SB - M CY - FRANCE IP - 2 VI - 66 JC - C4G EM - 7410 RO - O:41 RO - C:03 PMID- 4801954 CU - 86 TT - Sur un cas de leptospirose humaine a Saint-Laurent-du-Maroni (Guyane Francaise) EA - A SO - Bull Soc Pathol Exot Filiales 1973 Mar-Apr;66(2):269-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 74251188 AU - Cinco M AU - Olivotto M AU - Segonne J TI - [Serological research on the presence and spread of human leptospirosis in French Polynesia] LA - Fre MH - Antibody Specificity MH - Cross Reactions MH - English Abstract MH - Female MH - Hemagglutination Tests MH - Human MH - Leptospirosis/classification/diagnosis/*epidemiology MH - Male MH - Serotyping MH - Western Samoa PT - JOURNAL ARTICLE DA - 740823 DP - 1973 Mar-Apr IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 273-8 SB - M CY - FRANCE IP - 2 VI - 66 JC - C4G EM - 7410 RO - O:41 RO - C:03 PMID- 4801901 CU - 88 TT - Recherce serologique sur la presence et la diffusion des leptospiroses humaines en Polynesie francaise EA - A SO - Bull Soc Pathol Exot Filiales 1973 Mar-Apr;66(2):273-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 74009125 AU - Karaseva EV AU - Chernukha YG AU - Piskunova LA TI - Results of studying the time of survival of pathogenic leptospira under natural conditions. LA - Eng MH - Animal MH - Disease Reservoirs MH - Disease Vectors MH - Environmental Exposure MH - Hydrogen-Ion Concentration MH - Leptospira/*growth & development MH - Rodentia MH - *Soil Microbiology MH - Time Factors MH - Urine/microbiology MH - Water PT - JOURNAL ARTICLE DA - 731214 DP - 1973 Mar IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 339-45 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 17 JC - IEV EM - 7401 PMID- 4795565 CU - 90 SO - J Hyg Epidemiol Microbiol Immunol 1973 Mar;17(3):339-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 73197234 AU - Bernasovskaia EP AU - Mogireva LA AU - Kislova IF AU - Man'ko NI TI - [Development of a method for obtaining an erythrocytic leptospiral diagnosticum] LA - Rus MH - Animal MH - Drug Stability MH - English Abstract MH - Erythrocytes/*immunology MH - Freeze Drying MH - *Hemagglutination Tests MH - Human MH - Immunization MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Sheep/immunology PT - JOURNAL ARTICLE DA - 730810 DP - 1973 Mar TA - Zh Mikrobiol Epidemiol Immunobiol PG - 20-3 SB - M CY - USSR IP - 3 VI - 50 JC - Y9O EM - 7309 PMID- 4736408 CU - 89 TT - K razrabotke metoda polucheniia eritrotsitarnogo leptospiroznogo diagnostikuma. SO - Zh Mikrobiol Epidemiol Immunobiol 1973 Mar;50(3):20-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 73147030 AU - Shenberg E AU - Birnbaum S AU - Torten M TI - Epidemiologic-ecologic aspects of leptospira icterohaemorrhagiae carrier rodents in Israel seaports. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial MH - *Disease Vectors MH - Israel MH - *Leptospira interrogans MH - Leptospirosis MH - *Rats/immunology PT - JOURNAL ARTICLE DA - 730523 DP - 1973 Mar IS - 0041-3232 TA - Trop Geogr Med PG - 53-8 SB - M CY - NETHERLANDS IP - 1 VI - 25 JC - WGJ EM - 7307 PMID- 4693997 SO - Trop Geogr Med 1973 Mar;25(1):53-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 73128505 AU - Torten M AU - Schneider AS TI - Characterization of bacteria by ultraviolet spectroscopy. LA - Eng MH - Bacillus cereus/analysis MH - Bacteria/*classification MH - Circular Dichroism MH - Escherichia coli/analysis MH - Evaluation Studies MH - Leptospira/analysis MH - Mycobacterium/analysis MH - Species Specificity MH - *Spectrophotometry, Ultraviolet MH - Staphylococcus/analysis PT - JOURNAL ARTICLE DA - 730427 DP - 1973 Mar IS - 0022-1899 TA - J Infect Dis PG - 319-20 SB - A SB - M CY - UNITED STATES IP - 3 VI - 127 JC - IH3 EM - 7306 PMID- 4631878 CU - 91 SO - J Infect Dis 1973 Mar;127(3):319-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 74052853 AU - Meuzelaar HL AU - Kistemaker PG TI - A technique for fast and reproducible fingerprinting of bacteria by pyrolysis mass spectrometry. LA - Eng MH - Bacteriological Techniques MH - Heat MH - Leptospira/*classification MH - Methods MH - Neisseria/*classification MH - *Spectrum Analysis, Mass PT - JOURNAL ARTICLE DA - 740212 DP - 1973 Mar IS - 0003-2700 TA - Anal Chem PG - 587-90 CY - UNITED STATES IP - 3 VI - 45 JC - 4NR EM - 7403 PMID- 4586927 CU - 90 SO - Anal Chem 1973 Mar;45(3):587-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73185586 AU - Lake DE TI - Bovine leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial MH - Cattle MH - Cattle Diseases/*etiology MH - Female MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*veterinary MH - Mastitis, Bovine/etiology MH - Urinary Tract Infections/etiology/veterinary PT - JOURNAL ARTICLE DA - 730731 DP - 1973 Mar IS - 0048-0169 TA - N Z Vet J PG - 52 CY - NEW ZEALAND IP - 3 VI - 21 JC - OBZ EM - 7309 PMID- 4513424 CU - 88 SO - N Z Vet J 1973 Mar;21(3):52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [9 medline neighbors] UI - 73162189 AU - Myers DM TI - Procedure for drying leptospiral antibody on sand and sugar for serological studies in leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - *Blood Specimen Collection MH - Carbohydrates MH - Cattle/immunology MH - Diagnosis, Differential MH - Epidemiologic Methods MH - Evaluation Studies MH - Filtration MH - Human MH - Immune Sera MH - Leptospirosis/*diagnosis MH - Methods MH - Paper MH - Rabbits/immunology MH - Serodiagnosis MH - Silicon Dioxide MH - Specimen Handling PT - JOURNAL ARTICLE DA - 730621 DP - 1973 Mar IS - 0003-6919 TA - Appl Microbiol PG - 427-30 SB - M CY - UNITED STATES IP - 3 VI - 25 JC - 6K0 EM - 7308 PMID- 4349186 CU - 93 SO - Appl Microbiol 1973 Mar;25(3):427-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [34 medline neighbors] UI - 73215218 AU - Verin P TI - [Infectious pathology. I. Microbial pathology] LA - Fre MH - Antibiotics/adverse effects/therapeutic use MH - Bacterial Infections/complications/drug therapy/pathology MH - Conjunctivitis/pathology MH - Drug Hypersensitivity/etiology MH - Eye Diseases/drug therapy/etiology/*pathology MH - Eyelid Diseases/etiology/pathology MH - Human MH - Infection MH - Keratitis/pathology MH - Leptospirosis/complications MH - Optic Neuritis/pathology MH - Panophthalmitis/pathology MH - Retinitis/pathology MH - Syphilis/complications MH - Tuberculosis, Ocular/pathology MH - Uveitis/pathology PT - JOURNAL ARTICLE PT - REVIEW DA - 730912 DP - 1973 Mar IS - 0003-973X TA - Arch Ophtalmol Rev Gen Ophtalmol PG - 245-66 SB - M CY - FRANCE IP - 3 VI - 33 JC - BBU EM - 7310 RF - 311 PMID- 4268681 CU - 92 TT - Pathologie infectieuse. I. Pathologie microbienne. SO - Arch Ophtalmol Rev Gen Ophtalmol 1973 Mar;33(3):245-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [24 medline neighbors] UI - 73197252 AU - Tagi-Zade TA AU - Mardanly AS AU - Dzhabrailova FB TI - [Leptospiral carrier state in the Transcaucasian hedgehog (Erinaceus rumanicus transcaucasicus) in the Apsheron district of the Azerbaijani SSR] LA - Rus MH - Agglutination Tests MH - Animal MH - Antigen-Antibody Reactions MH - Azerbaijan MH - Carrier State/*microbiology MH - Cross Reactions MH - Culture Media MH - English Abstract MH - *Hedgehogs MH - Hemadsorption MH - Kidney/microbiology MH - Leptospirosis/*microbiology MH - Liver/microbiology MH - Microscopy MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 730810 DP - 1973 Mar TA - Zh Mikrobiol Epidemiol Immunobiol PG - 81-3 SB - M CY - USSR IP - 3 VI - 50 JC - Y9O EM - 7309 PMID- 4268104 CU - 92 TT - Nositel'stvo leptospir u zakavkazskikh ezhei (Erinaceus rumanicus transcaucasicus) v raione Apsherona Azerbaidzhanskoi SS. SO - Zh Mikrobiol Epidemiol Immunobiol 1973 Mar;50(3):81-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 73201834 AU - Fuzi M TI - [Vancomycin-resistance of leptospirae] LA - Ger MH - Culture Media MH - Dose-Response Relationship, Drug MH - Drug Resistance, Microbial MH - English Abstract MH - Genetics, Microbial MH - Leptospira/*drug effects/growth & development MH - Microbial Sensitivity Tests MH - Selection (Genetics) MH - Vancomycin/*pharmacology PT - JOURNAL ARTICLE DA - 730818 DP - 1973 Mar IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 368-71 SB - M CY - GERMANY, WEST IP - 2 VI - 223 JC - Y52 EM - 7310 PMID- 4145845 CU - 94 TT - Die Vancomycin-Resistenz der leptospiren. SO - Zentralbl Bakteriol [Orig A] 1973 Mar;223(2):368-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 74040708 AU - Zorina ZM AU - Ivanova MN AU - Martynova AP TI - [Period of survival of serum antibodies in healthy persons subjected to intramuscular injections of antileptospirosis gamma-globulin] LA - Rus MH - Adolescence MH - Adult MH - Antibodies/*analysis MH - *Antibody Formation MH - Female MH - Gamma-Globulins/*administration & dosage MH - Human MH - Injections, Intramuscular MH - Leptospirosis/*immunology/prevention & control MH - Male PT - JOURNAL ARTICLE DA - 740124 DP - 1973 Mar IS - 0038-5077 TA - Sov Med PG - 146 CY - USSR IP - 3 VI - 36 JC - UW7 EM - 7403 PMID- 4127893 CU - 95 TT - Dlitel'nost' sokhraneniia syvorotochnykh antitel u zdorovykh liudei, poluchivshikh bnutrimyshechnye in'ektsii protivoleptospiroznogo gamma- globulina. SO - Sov Med 1973 Mar;36(3):146 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 73128038 AU - Wierzbowska A AU - Stepien R AU - Geraga W AU - Kolsut H AU - Zambrzycki J TI - [Leptospirosis presenting as thrombotic thrombopenic purpura] LA - Pol MH - Autopsy MH - Human MH - Leptospirosis/pathology MH - Male MH - Purpura, Thrombotic Thrombocytopenic/*diagnosis MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 730426 DP - 1973 Feb 15 IS - 0043-5147 TA - Wiad Lek PG - 359-62 CY - POLAND IP - 4 VI - 26 JC - XOA EM - 7306 PMID- 4734655 CU - 85 TT - Leptospiroza, przebiegajaca pod postacia zakrzepowej plamicy maloplytkowej. SO - Wiad Lek 1973 Feb 15;26(4):359-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 73145161 AU - Twigg GI AU - Hughes DM AU - McDiarmid A TI - Antibodies to Leptospira grippotyphosa in British wild mammals. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Cattle MH - Disease Reservoirs MH - Goats/immunology MH - Great Britain MH - Insectivora/immunology MH - Leptospira/*immunology MH - Mammals/*immunology MH - Rabbits/immunology MH - Rodentia/immunology PT - JOURNAL ARTICLE DA - 730518 DP - 1973 Feb 3 IS - 0042-4900 TA - Vet Rec PG - 119 SB - M CY - ENGLAND IP - 5 VI - 92 JC - XBS EM - 7307 PMID- 4693392 SO - Vet Rec 1973 Feb 3;92(5):119 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 73162672 AU - Thurner J AU - Haas P TI - [Liver changes in leptospira infections (Leptospira icterohaemorrhagia and Leptospira pomona)] LA - Ger MH - Adult MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - Cholestasis/pathology MH - English Abstract MH - Hepatitis A/pathology MH - Human MH - Leptospirosis/immunology/mortality/*pathology MH - Liver Diseases/immunology/mortality/*pathology MH - Male MH - Medical History Taking MH - Middle Age MH - Weil's Disease/immunology/*pathology PT - JOURNAL ARTICLE DA - 730621 DP - 1973 Feb 2 IS - 0027-2973 TA - Munch Med Wochenschr PG - 147-50 SB - M CY - GERMANY, WEST IP - 5 VI - 115 JC - MMW EM - 7308 PMID- 4739718 CU - 86 TT - Leberveranderungen bei Leptospiren-Infektionen (Leptospira icterohaemorrhagia und Leptospira pomona. SO - Munch Med Wochenschr 1973 Feb 2;115(5):147-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74074255 AU - Chernoshtanov AA TI - [Epizootology and prevention of leptospirosis in Tselinograd Province] LA - Rus MH - Animal MH - Cattle MH - Horses MH - Leptospirosis/epidemiology/prevention & control/*veterinary MH - Sheep MH - Swine MH - USSR PT - JOURNAL ARTICLE DA - 740306 DP - 1973 Feb IS - 0042-4846 TA - Veterinariia PG - 53-4 CY - USSR VI - 3 JC - XCC EM - 7404 PMID- 4770051 CU - 88 TT - Epizootologiia i profilaktika leptospiroza v Tselinogradskoi oblasti. SO - Veterinariia 1973 Feb;3:53-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74074254 AU - Kuz'min GG AU - Riabtsev MI TI - [Some problems in the epizootology and diagnosis of leptospirosis] LA - Rus MH - Animal MH - Cattle MH - Leptospirosis/diagnosis/epidemiology/*veterinary MH - Swine MH - Swine Diseases/*diagnosis MH - USSR PT - JOURNAL ARTICLE DA - 740306 DP - 1973 Feb IS - 0042-4846 TA - Veterinariia PG - 51-3 CY - USSR VI - 3 JC - XCC EM - 7404 PMID- 4770050 CU - 88 TT - Nekotorye voprosy epizootologii i diagnostiki leptospiroza. SO - Veterinariia 1973 Feb;3:51-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 73204553 AU - Morin M AU - Mornet P TI - [Influenza and influenza syndromes] LA - Fre MH - Bacterial Infections/diagnosis MH - Diagnosis, Differential MH - Influenza/diagnosis MH - Leptospirosis/diagnosis MH - Mycoplasma Infections/diagnosis MH - Q Fever/diagnosis MH - Syndrome MH - Virus Diseases/diagnosis PT - JOURNAL ARTICLE DA - 730823 DP - 1973 Feb 1 TA - Rev Prat PG - 459-64 CY - FRANCE IP - 7 VI - 23 JC - T1D EM - 7310 PMID- 4713468 CU - 90 LI - F TT - Grippe et syndromes grippaux. SO - Rev Prat 1973 Feb 1;23(7):459-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 73091536 AU - Morsi HM AU - Shibley GP AU - Strother HL TI - Renal leptospirosis: challenge exposure to vaccinated and nonvaccinated cattle to Leptospira icterohaemorrhagiae and Leptospira canicola. LA - Eng MH - Agglutination Tests MH - Animal MH - Bacterial Vaccines/administration & dosage MH - Blood/microbiology MH - Cattle MH - Cattle Diseases/immunology/pathology/*prevention & control MH - Hamsters MH - Immunization, Passive MH - Kidney Diseases/immunology/pathology/prevention & control/*veterinary MH - Leptospira canicola/*immunology/isolation & purification MH - Leptospira interrogans/*immunology/isolation & purification MH - Leptospirosis/immunology/pathology/prevention & control/*veterinary MH - Liver/pathology MH - Swine MH - Urine/microbiology MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 730402 DP - 1973 Feb IS - 0002-9645 TA - Am J Vet Res PG - 175-9 SB - M CY - UNITED STATES IP - 2 VI - 34 JC - 40C EM - 7305 PMID- 4685541 SO - Am J Vet Res 1973 Feb;34(2):175-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [168 medline neighbors] UI - 73091535 AU - Stalheim OH TI - Safety of viable, avirulent Leptospira pomona vaccine in pregnant cows. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals, Newborn MH - *Bacterial Vaccines/administration & dosage MH - Bacteriuria MH - Cattle MH - Cattle Diseases/immunology/*prevention & control MH - Female MH - Injections, Intramuscular MH - Injections, Subcutaneous MH - Kidney/microbiology MH - Leptospira/*immunology MH - Leptospirosis/immunology/prevention & control/*veterinary MH - Pregnancy MH - *Pregnancy, Animal MH - Virulence PT - JOURNAL ARTICLE DA - 730402 DP - 1973 Feb IS - 0002-9645 TA - Am J Vet Res PG - 173-4 SB - M CY - UNITED STATES IP - 2 VI - 34 JC - 40C EM - 7305 PMID- 4685540 SO - Am J Vet Res 1973 Feb;34(2):173-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 73148164 AU - Schiemann DA TI - Survivor curves for Leptospira autumnalis Akiyami A based on most- probable-number values. LA - Eng MH - *Bacteriological Techniques MH - Cell Count MH - Cell Survival MH - Culture Media MH - Factor Analysis, Statistical MH - Hydrogen-Ion Concentration MH - *Leptospira/growth & development MH - Models, Biological MH - Probability MH - Temperature PT - JOURNAL ARTICLE DA - 730524 DP - 1973 Feb IS - 0003-6919 TA - Appl Microbiol PG - 240-3 SB - M CY - UNITED STATES IP - 2 VI - 25 JC - 6K0 EM - 7307 PMID- 4571659 CU - 90 SO - Appl Microbiol 1973 Feb;25(2):240-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 73148163 AU - Schiemann DA TI - Application of the most-probable-number procedure to suspensions of Leptospira autumnalis Akiyami A. LA - Eng MH - *Bacteriological Techniques MH - Cell Count MH - Culture Media MH - Factor Analysis, Statistical MH - *Leptospira/growth & development MH - Probability PT - JOURNAL ARTICLE DA - 730524 DP - 1973 Feb IS - 0003-6919 TA - Appl Microbiol PG - 235-9 SB - M CY - UNITED STATES IP - 2 VI - 25 JC - 6K0 EM - 7307 PMID- 4571658 CU - 90 SO - Appl Microbiol 1973 Feb;25(2):235-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [43 medline neighbors] UI - 73075841 TI - Synopsis of vaccination procedures for dogs. LA - Eng MH - Adenoviruses, Canine/immunology MH - Animal MH - Bacterial Vaccines/administration & dosage MH - Distemper Virus, Canine/immunology MH - Dog Diseases/*prevention & control MH - Dogs MH - Leptospira/immunology MH - Rabies Vaccine/administration & dosage MH - Vaccination/*veterinary MH - Viral Vaccines/administration & dosage PT - JOURNAL ARTICLE DA - 730308 DP - 1973 Feb 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 228-30 SB - M CY - UNITED STATES IP - 3 VI - 162 JC - HAV EM - 7304 PMID- 4345835 CU - 93 NI - A SO - J Am Vet Med Assoc 1973 Feb 1;162(3):228-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 74074256 AU - Stepanenko PP AU - Andreeva ZA AU - Dulytsev DA TI - [Experience in eliminating leptospirosis from a farm] LA - Rus MH - Animal MH - Female MH - Leptospirosis/prevention & control/*veterinary MH - Russia MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 740306 DP - 1973 Feb IS - 0042-4846 TA - Veterinariia PG - 54-6 CY - USSR VI - 3 JC - XCC EM - 7404 PMID- 4272285 CU - 92 TT - Iz opyta ozdorovleniia khoziaistva ot leptospiroza. SO - Veterinariia 1973 Feb;3:54-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 73202730 AU - Mateew D AU - Manew C TI - [Occurrence of serological types of the serological group australis of leptospirae in Bulgaria] LA - Ger MH - Animal MH - Bulgaria MH - Cross Reactions MH - English Abstract MH - Gerbillinae MH - Hedgehogs MH - Leptospira/*isolation & purification MH - Mice MH - Rats MH - Serotyping MH - Species Specificity PT - JOURNAL ARTICLE DA - 730821 DP - 1973 Feb IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 235-9 SB - M CY - GERMANY, WEST IP - 2 VI - 223 JC - Y52 EM - 7310 PMID- 4145880 CU - 94 TT - Uber das Vorkommen von Leptospiren-Serotypen der Serogruppe Australis in Bulgarien. SO - Zentralbl Bakteriol [Orig A] 1973 Feb;223(2):235-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 73202729 AU - Manev H AU - Yanakieva M TI - Typing of leptospira strains of the hebdomadis serogropuy with absorbed sera. LA - Eng MH - Absorption MH - Animal MH - Cross Reactions MH - Immune Sera MH - Leptospira/*classification MH - Rabbits/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 730821 DP - 1973 Feb IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 228-34 SB - M CY - GERMANY, WEST IP - 2 VI - 223 JC - Y52 EM - 7310 PMID- 4145879 CU - 94 SO - Zentralbl Bakteriol [Orig A] 1973 Feb;223(2):228-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 73091554 AU - Donham KJ AU - Crawford RP TI - Effects of fluorescein isothiocyanate labeling on staining characteristics of a fluorescent antibody conjugate for the diagnosis of leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial MH - Buffers MH - Chromatography, Gel MH - Chromatography, Ion Exchange MH - Cross Reactions MH - *Fluoresceins/isolation & purification MH - *Fluorescent Antibody Technique MH - Gamma-Globulins/isolation & purification MH - Guinea Pigs MH - Kidney/microbiology MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis/immunology/*veterinary MH - Rabbits/immunology MH - Thiocyanates/isolation & purification MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 730402 DP - 1973 Feb IS - 0002-9645 TA - Am J Vet Res PG - 267-71 SB - M CY - UNITED STATES IP - 2 VI - 34 JC - 40C EM - 7305 PMID- 4119566 CU - 95 SO - Am J Vet Res 1973 Feb;34(2):267-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73147922 AU - Whyte GG AU - Burke CJ TI - Leptospirosis in North-Western Tasmania. LA - Eng MH - Adult MH - Agricultural Workers' Diseases/*epidemiology MH - Animal MH - Australia MH - Case Report MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 730524 DP - 1973 Jan 27 IS - 0025-729X TA - Med J Aust PG - 173-4 SB - M CY - AUSTRALIA IP - 4 VI - 1 JC - M26 EM - 7307 PMID- 4735100 CU - 88 SO - Med J Aust 1973 Jan 27;1(4):173-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73147913 TI - Leptospirosis in Australia. LA - Eng MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/epidemiology MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Serotyping PT - JOURNAL ARTICLE DA - 730524 DP - 1973 Jan 27 IS - 0025-729X TA - Med J Aust PG - 150-1 SB - M CY - AUSTRALIA IP - 4 VI - 1 JC - M26 EM - 7307 PMID- 4735099 CU - 88 NI - A SO - Med J Aust 1973 Jan 27;1(4):150-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 73147921 AU - Sitprija V AU - Chusilp S TI - Renal failure and hyperbilirubinaemia in leptospirosis. Treatment with exchange transfusion. LA - Eng MH - Adult MH - Anuria/etiology MH - *Exchange Transfusion, Whole Blood MH - Human MH - Hyperbilirubinemia/etiology/*therapy MH - Kidney Failure, Acute/etiology/*therapy MH - Leptospirosis/complications/*therapy MH - Male MH - Peritoneal Dialysis PT - JOURNAL ARTICLE DA - 730524 DP - 1973 Jan 27 IS - 0025-729X TA - Med J Aust PG - 171-3 SB - M CY - AUSTRALIA IP - 4 VI - 1 JC - M26 EM - 7307 PMID- 4734078 SO - Med J Aust 1973 Jan 27;1(4):171-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 76225333 AU - Popova EM AU - Stoianova NA TI - [Differentiation of antibodies according to immunoglobulin class in leptospirosis] LA - Rus MH - Animal MH - *Antibody Formation MH - Human MH - Immunoglobulins/*analysis MH - Leptospirosis/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 760901 DP - 1973 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 134-42 CY - USSR VI - 41 JC - VZR EM - 7610 PMID- 4808403 CU - 89 TT - Differentsiatsiia antitel po klassam immunoglobulinov pri leptospirozakh SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1973;41:134-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 76017896 AU - Santa Rosa CA AU - da Silva AS AU - Giorgi W AU - Machado A TI - [Isolation of leptospira serotype pomona and brucella suis from swines from the State of Santa Catarina, Brazil (author's transl)] LA - Por MH - Abortion, Veterinary/epidemiology/*etiology MH - Animal MH - Brazil MH - Brucellosis/epidemiology/*veterinary MH - English Abstract MH - Female MH - Leptospirosis/epidemiology/*veterinary MH - Pregnancy MH - Pregnancy, Animal MH - Serotyping MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 751122 DP - 1973 Jan-Mar IS - 0020-3653 TA - Arq Inst Biol (Sao Paulo) PG - 29-32 SB - M CY - BRAZIL IP - 1 VI - 40 JC - 8VF EM - 7601 PMID- 4808063 CU - 88 TT - Isolamento de Leptospira, sorotipo Pomona e Brucella suis, de suinos do estado de Santa Catarina EA - A SO - Arq Inst Biol (Sao Paulo) 1973 Jan-Mar;40(1):29-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 75199305 AU - Obiger G TI - [Diagnosis of Leptospirosis using the allergic reaction test] LA - Ger MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibody Formation MH - *Antigen-Antibody Reactions MH - Antigens, Bacterial/analysis MH - Cattle MH - Cattle Diseases/*diagnosis MH - Complement Fixation Tests/methods MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/immunology/*veterinary MH - Rabbits MH - Serodiagnosis/veterinary MH - Swine MH - Swine Diseases/*diagnosis MH - Zoonoses PT - JOURNAL ARTICLE DA - 751010 DP - 1973 IS - 0303-6286 TA - Tierarztl Prax PG - 261-5 SB - M CY - GERMANY, WEST IP - 3 VI - 1 JC - VS4 EM - 7511 RO - M:BDS PMID- 4806110 LR - 850301 TT - Die Diagnose der Leptospirose mit Hilfe der Allergieprobe SO - Tierarztl Prax 1973;1(3):261-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75162605 AU - Mazzonelli JM AU - Dorta CT TI - [Influence of agricultural pesticides in the isolation of leptospira from polluted water] LA - Por MH - Argentina MH - Drug Resistance, Microbial MH - English Abstract MH - Human MH - Insecticides/*pharmacology MH - Insecticides, Organochlorine/pharmacology MH - Insecticides, Organophosphate/pharmacology MH - Leptospira/*drug effects/isolation & purification MH - Leptospirosis/prevention & control MH - Microbial Sensitivity Tests MH - *Water Microbiology MH - Water Pollution PT - JOURNAL ARTICLE DA - 750718 DP - 1973 Jan-Dec TA - An Inst Hig Med Trop (Lisb) PG - 231-41 CY - PORTUGAL IP - 1-4 VI - 1 JC - 4DL EM - 7509 PMID- 4805669 CU - 89 TT - Influencia de los plaguicidas agricolas en el aislamiento de leptospiras a partir de aguas contaminadas EA - A SO - An Inst Hig Med Trop (Lisb) 1973 Jan-Dec;1(1-4):231-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74144237 AU - Mailloux M TI - [Current status of human leptospirosis in the French Antilles] LA - Fre MH - Human MH - Leptospira/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis/*epidemiology MH - Serodiagnosis MH - Socioeconomic Factors MH - Weil's Disease/epidemiology MH - West Indies PT - JOURNAL ARTICLE DA - 740614 DP - 1973 Jan-Feb IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 46-54 SB - M CY - FRANCE IP - 1 VI - 66 JC - C4G EM - 7408 PMID- 4801791 CU - 88 TT - Etat actuel des leptospiroses humaines aux Antilles Franc Aises. SO - Bull Soc Pathol Exot Filiales 1973 Jan-Feb;66(1):46-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 74304550 AU - Fuzi M TI - Metronidazole resistance, a genus-specific feature of leptospires. LA - Eng MH - Aerobiosis MH - Anaerobiosis MH - Cell Movement/drug effects MH - *Drug Resistance, Microbial MH - Leptospira/classification/*drug effects/growth & development MH - Metronidazole/*pharmacology MH - Species Specificity PT - JOURNAL ARTICLE DA - 741106 DP - 1973 IS - 0001-6187 TA - Acta Microbiol Acad Sci Hung PG - 333-6 SB - M CY - HUNGARY IP - 4 VI - 20 JC - 16A EM - 7412 RO - O:45 RO - C:00 PMID- 4794982 CU - 90 SO - Acta Microbiol Acad Sci Hung 1973;20(4):333-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 74297708 AU - Mazzonelli J AU - Dorta de Mazzonelli GT TI - A study on the mechanism of the sodium bicarbonate test in the differentiation of saprophytic and pathogenic leptsopirae. LA - Eng MH - Bicarbonates/*pharmacology MH - Leptospira/*drug effects/growth & development/pathogenicity MH - Sodium PT - JOURNAL ARTICLE DA - 741106 DP - 1973 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 165-6 SB - M CY - ITALY IP - 2 VI - 9 JC - 5BP EM - 7412 RO - O:46 RO - C:01 PMID- 4794857 SO - Ann Ist Super Sanita 1973;9(2):165-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74105984 AU - Kanareikina SK TI - [Leptospira multiplication on solid culture media] LA - Rus MH - Comparative Study MH - Culture Media MH - English Abstract MH - Leptospira/*growth & development/pathogenicity MH - Species Specificity MH - Time Factors PT - JOURNAL ARTICLE DA - 740423 DP - 1973 Jan TA - Zh Mikrobiol Epidemiol Immunobiol PG - 90-2 SB - M CY - USSR IP - 1 VI - 50 JC - Y9O EM - 7406 PMID- 4780113 CU - 90 TT - V voprosu o razmnozhenii leptospir na plotnykh pitatel'nykh sredakh. SO - Zh Mikrobiol Epidemiol Immunobiol 1973 Jan;50(1):90-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74105374 AU - Sarrat H AU - Doutre MP AU - Ruscher H TI - [On the epidemiology of leptospirosis in the region of Cap-Vert (Senegal)] LA - Fre MH - Animal MH - English Abstract MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Methods MH - Rats MH - Senegal PT - JOURNAL ARTICLE DA - 740423 DP - 1973 IS - 0049-1101 TA - Bull Soc Med Afr Noire Lang Fr PG - 236-9 CY - SENEGAL IP - 2 VI - 18 JC - C1S EM - 7406 PMID- 4779789 CU - 90 TT - Note sur l'epidemiologie des leptospiroses dans la region du Cap-Vert (Senegal. SO - Bull Soc Med Afr Noire Lang Fr 1973;18(2):236-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 74105373 AU - Sankale M AU - Sow AM AU - Ruscher H AU - Sarrat H TI - [Leptospirosis in the hospital environment in Dakar (results of a new survey)] LA - Fre MH - Adult MH - English Abstract MH - Female MH - Hospitals MH - Human MH - *Leptospirosis/diagnosis/epidemiology/therapy MH - Male MH - Middle Age MH - Senegal PT - JOURNAL ARTICLE DA - 740423 DP - 1973 IS - 0049-1101 TA - Bull Soc Med Afr Noire Lang Fr PG - 227-35 CY - SENEGAL IP - 2 VI - 18 JC - C1S EM - 7406 PMID- 4779788 CU - 88 TT - La leptospirose en milieu hospitalier a Dakar (resultats d'und nouvelle enquete. SO - Bull Soc Med Afr Noire Lang Fr 1973;18(2):227-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 73202995 AU - Guibert JM AU - Acar JF TI - [Clinical and bacteriological evaluation of amoxicillin in infections not caused by enterobacteria] LA - Fre MH - Adolescence MH - Adult MH - Aged MH - Amines/adverse effects/therapeutic use MH - Child MH - English Abstract MH - Female MH - Human MH - Infection/*drug therapy MH - Leptospirosis/drug therapy MH - Male MH - Middle Age MH - Penicillins/adverse effects/*therapeutic use MH - Pneumococcal Infections/drug therapy MH - Staphylococcal Infections/drug therapy MH - Streptococcal Infections/drug therapy MH - Temperature MH - Urinary Tract Infections/drug therapy PT - JOURNAL ARTICLE DA - 730822 DP - 1973 IS - 0009-3157 TA - Chemotherapy PG - Suppl:81-90 SB - M CY - SWITZERLAND VI - 18 JC - D15 EM - 7310 RO - M:JJK PMID- 4736521 LR - 800306 CU - 85 TT - Evaluation clinique et bacteriologique de l'amoxicilline en dehors des infections a enterobacteries. SO - Chemotherapy 1973;18:Suppl:81-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73206931 AU - Ioli A AU - Munao F AU - Buzzanca E TI - [On a test for differentiation of Leptospira] LA - Ita MH - Agglutination Tests MH - Culture Media MH - Detergents MH - Diagnosis, Differential MH - English Abstract MH - Leptospira/*classification MH - Leptospirosis/diagnosis MH - Methods MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE DA - 730831 DP - 1973 Jan-Feb IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 8-11 SB - M CY - ITALY IP - 1 VI - 52 JC - AKG EM - 7310 PMID- 4714454 CU - 90 TT - Su di un test per la differenziazione delle Leptospire. SO - Boll Ist Sieroter Milan 1973 Jan-Feb;52(1):8-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 73175715 AU - Rosa CA AU - Magalhaes M AU - Sulzer CR AU - Lima CA TI - Human leptospirosis caused by serotype Alexi in Brazil. LA - Eng MH - Adult MH - Agglutination Tests MH - Brazil MH - Case Report MH - Human MH - *Leptospira MH - Leptospirosis/*microbiology MH - Male MH - Serotyping PT - JOURNAL ARTICLE DA - 730709 DP - 1973 Jan-Feb IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 38-42 CY - BRAZIL IP - 1 VI - 15 JC - S9D EM - 7308 PMID- 4703905 SO - Rev Inst Med Trop Sao Paulo 1973 Jan-Feb;15(1):38-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 73148682 AU - Munday BL AU - Corbould A TI - Leptospira pomona infection in wombats. LA - Eng MH - Animal MH - Australia MH - Leptospirosis/complications/epidemiology/immunology/*veterinary MH - *Marsupialia MH - Nephritis, Interstitial/epidemiology/etiology/immunology/veterinary PT - JOURNAL ARTICLE DA - 730524 DP - 1973 Jan IS - 0090-3558 TA - J Wildl Dis PG - 72-3 SB - M CY - UNITED STATES IP - 1 VI - 9 JC - KEM EM - 7307 PMID- 4694593 CU - 88 SO - J Wildl Dis 1973 Jan;9(1):72-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73130232 AU - Fish NA AU - Kingscote B TI - Protection of gilts against leptospirosis by use of a live vaccine. LA - Eng MH - Animal MH - Female MH - Leptospira/*immunology MH - Leptospirosis/prevention & control/*veterinary MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination MH - *Viral Vaccines PT - JOURNAL ARTICLE DA - 730501 DP - 1973 Jan IS - 0008-5286 TA - Can Vet J PG - 12-5 CY - CANADA IP - 1 VI - 14 JC - CLS EM - 7306 PMID- 4689268 SO - Can Vet J 1973 Jan;14(1):12-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 73082752 AU - Morsi HM AU - Shibley GP TI - Cellular and whole-culture bivalent leptospiral bacterins: safety and potency in guinea pigs and hamsters. LA - Eng MH - Animal MH - Bacterial Vaccines/administration & dosage/adverse effects/isolation & purification/*standards MH - Culture Media MH - Evaluation Studies MH - *Guinea Pigs MH - *Hamsters MH - Injections, Intraperitoneal MH - Leptospira/growth & development/*immunology MH - Leptospira canicola/growth & development/immunology MH - Leptospira interrogans/growth & development/immunology MH - Leptospirosis/immunology/veterinary MH - Male PT - JOURNAL ARTICLE DA - 730315 DP - 1973 Jan IS - 0002-9645 TA - Am J Vet Res PG - 115-7 SB - M CY - UNITED STATES IP - 1 VI - 34 JC - 40C EM - 7305 PMID- 4683968 SO - Am J Vet Res 1973 Jan;34(1):115-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 73082751 AU - Morsi HM AU - Shibley GP AU - Binkley FW TI - Evaluation of a polyvalent leptospiral bacterin: safety in guinea pigs and potency in hamsters. LA - Eng MH - Animal MH - Bacterial Vaccines/administration & dosage/adverse effects/*standards MH - Evaluation Studies MH - *Guinea Pigs MH - *Hamsters MH - Injections, Intraperitoneal MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/veterinary MH - Male MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 730315 DP - 1973 Jan IS - 0002-9645 TA - Am J Vet Res PG - 113-4 SB - M CY - UNITED STATES IP - 1 VI - 34 JC - 40C EM - 7305 PMID- 4683967 SO - Am J Vet Res 1973 Jan;34(1):113-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73067966 AU - Sulzer CR AU - Jones WL TI - A modified semi-micro method for the test for leptospirosis. LA - Eng MH - *Agglutination Tests MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial MH - Human MH - Immune Sera MH - Leptospira/immunology MH - Leptospirosis/*immunology MH - Methods MH - Rabbits/immunology PT - JOURNAL ARTICLE DA - 730301 DP - 1973 Jan IS - 0017-9035 TA - Health Lab Sci PG - 13-7 SB - M CY - UNITED STATES IP - 1 VI - 10 JC - G2C EM - 7304 PMID- 4682557 CU - 90 SO - Health Lab Sci 1973 Jan;10(1):13-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 73171123 TI - [Emergency treatment and pathogenesis of leptospirosis with massive pulmonary hemorrhage] LA - Chi MH - Animal MH - *Emergencies MH - English Abstract MH - Guinea Pigs MH - Hemorrhage/*etiology MH - Human MH - *Leptospirosis/complications/drug therapy/etiology MH - Lung Diseases/*etiology MH - Weil's Disease/drug therapy PT - JOURNAL ARTICLE DA - 730702 DP - 1973 IS - 0376-2491 TA - Chung Hua I Hsueh Tsa Chih PG - 279-82 CY - CHINA VI - 5 JC - CDG EM - 7308 RO - M:BDS PMID- 4633887 LR - 850923 CU - 91 NI - A SO - Chung Hua I Hsueh Tsa Chih 1973;5:279-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 73146645 AU - Palit A AU - Gulasekharam J TI - Genus-specific leptospiral antigen and its possible use in laboratory diagnosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibody Formation MH - *Antigens, Bacterial MH - Cross Reactions MH - Erythrocytes/immunology MH - Freeze Drying MH - Hemagglutination Tests MH - Human MH - IgM MH - Immune Sera MH - Immunodiffusion MH - Immunoelectrophoresis MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/immunology MH - Mercaptoethanol MH - Rabbits MH - Serodiagnosis MH - Sheep/immunology PT - JOURNAL ARTICLE DA - 730523 DP - 1973 Jan IS - 0021-9746 TA - J Clin Pathol PG - 7-16 SB - A SB - M CY - ENGLAND IP - 1 VI - 26 JC - HT3 EM - 7307 PMID- 4632761 CU - 91 SO - J Clin Pathol 1973 Jan;26(1):7-16 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 75004395 AU - Bondarenko BN TI - [Quantitative determination of lipids by thin-layer chromatography] LA - Rus MH - Chemistry, Analytical/methods MH - *Chromatography, Thin Layer MH - Comparative Study MH - Diglycerides/analysis MH - English Abstract MH - Fatty Acids/analysis MH - Leptospira/analysis MH - Lipids/*analysis MH - Phospholipids/analysis MH - Proteus mirabilis/analysis MH - Triglycerides/analysis PT - JOURNAL ARTICLE DA - 741216 DP - 1973 IS - 0042-8809 TA - Vopr Med Khim PG - 438-43 SB - M CY - USSR IP - 4 VI - 19 JC - XIQ EM - 7501 PMID- 4605903 CU - 90 TT - Kolichestvennoe opredelenie lipidov pri khromatografirovanii v tonkikh sloiakh EA - A SO - Vopr Med Khim 1973;19(4):438-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [43 medline neighbors] UI - 74114683 AU - Steele JH TI - The zoonoses: an epidemiologist's viewpoint. LA - Eng MH - Animal MH - Anthrax/prevention & control MH - Bacterial Infections/veterinary MH - Brucellosis/veterinary MH - Brucellosis, Bovine/prevention & control MH - Cattle MH - Cestode Infections/veterinary MH - Chlamydia Infections/veterinary MH - Escherichia coli Infections/veterinary MH - Glanders/prevention & control MH - Goats MH - Horses MH - Human MH - Leptospirosis/veterinary MH - Melioidosis/prevention & control MH - Mycoses/veterinary MH - Nematode Infections/veterinary MH - Q Fever/veterinary MH - Rabies MH - Salmonella Infections/veterinary MH - Swine MH - Toxoplasmosis/veterinary MH - Trematode Infections/veterinary MH - Tuberculosis MH - Tuberculosis, Avian/prevention & control MH - Tuberculosis, Bovine/prevention & control MH - Virus Diseases/veterinary MH - Zoonoses/*classification/microbiology PT - JOURNAL ARTICLE PT - REVIEW DA - 740502 DP - 1973 IS - 0079-6174 TA - Prog Clin Pathol PG - 239-86 CY - UNITED STATES VI - 5 JC - Q0P EM - 7406 RF - 25 PMID- 4592960 CU - 90 SO - Prog Clin Pathol 1973;5:239-86 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [46 medline neighbors] UI - 74076445 AU - Petrov RV TI - [Modern problems of immunogenetics] LA - Rus MH - Animal MH - Antibody Formation MH - Chromosomes/immunology MH - Crosses, Genetic MH - English Abstract MH - Erythrocytes/immunology MH - France MH - Genotype MH - Histocompatibility Antigens/analysis MH - Homeostasis MH - Human MH - Immunization MH - Immunization, Secondary MH - *Immunogenetics MH - Immunologic Deficiency Syndromes/immunology MH - Kidney/immunology MH - Leptospira/immunology MH - Mast Cells/immunology MH - Mice MH - Mice, Inbred C3H MH - Mice, Inbred C57BL MH - Tissue Donors MH - Transplantation Immunology MH - USSR PT - JOURNAL ARTICLE PT - REVIEW DA - 740308 DP - 1973 TA - Vestn Akad Med Nauk SSSR PG - 81-90 CY - USSR IP - 1 VI - 28 JC - X9A EM - 7404 PMID- 4589094 CU - 90 TT - Sovremennye problemy immunogenetiki. SO - Vestn Akad Med Nauk SSSR 1973;28(1):81-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 74036154 AU - Nasilowska M TI - [Immunofluorescence method in the diagnosis of leptospirosis] LA - Pol MH - Agglutination Tests MH - Antibodies, Bacterial/analysis MH - English Abstract MH - Fluorescent Antibody Technique MH - Human MH - Leptospirosis/*diagnosis/immunology PT - JOURNAL ARTICLE DA - 740119 DP - 1973 IS - 0033-2100 TA - Przegl Epidemiol PG - 395-401 CY - POLAND IP - 3 VI - 27 JC - Q8T EM - 7402 PMID- 4585490 CU - 90 TT - Proby zastosowania metody immunofluorescencji do diagnostyki leptospiroz. SO - Przegl Epidemiol 1973;27(3):395-401 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 73190501 AU - Kadlcik K AU - Salak J AU - Roch P TI - The agglutinating and immunofluorescent antibodies of antileptospiral rabbit sera. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antibodies, Bacterial MH - Antibody Formation MH - Chromatography, DEAE-Cellulose MH - Chromatography, Gel MH - Fluorescent Antibody Technique MH - IgG/biosynthesis/isolation & purification MH - IgM/biosynthesis MH - Immune Sera MH - Immunization MH - Leptospira/immunology MH - Leptospirosis/*immunology MH - Rabbits/immunology MH - Serotyping MH - Species Specificity MH - Time Factors PT - JOURNAL ARTICLE DA - 730806 DP - 1973 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 55-69 SB - M CY - CZECHOSLOVAKIA IP - 1 VI - 17 JC - IEV EM - 7309 PMID- 4575462 CU - 90 SO - J Hyg Epidemiol Microbiol Immunol 1973;17(1):55-69 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 73077077 AU - Hirschberg N AU - Vaughn J TI - Antibodies in bovine urine in leptospirosis. LA - Eng MH - Animal MH - Antibodies, Bacterial/*urine MH - Cattle MH - Cattle Diseases/*immunology/urine MH - Fluorescent Antibody Technique MH - Leptospirosis/immunology/urine/*veterinary PT - JOURNAL ARTICLE DA - 730308 DP - 1973 Jan IS - 0042-4889 TA - Vet Med Small Anim Clin PG - 67 passim CY - UNITED STATES IP - 1 VI - 68 JC - XBO EM - 7304 PMID- 4567062 CU - 90 SO - Vet Med Small Anim Clin 1973 Jan;68(1):67 passim ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 77102932 AU - Cole JR Jr AU - Pursell AR TI - Serologic incidence of leptospirosis in Georgia horses. LA - Eng MH - Animal MH - Antibodies, Bacterial/*analysis MH - Georgia MH - Horses/*immunology MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 770315 DP - 1973 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 632-7 CY - UNITED STATES IP - 77 JC - PY5 EM - 7705 RO - M:CNR PMID- 4534743 LR - 930405 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1973;(77):632-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 77102928 AU - Lyle WE AU - Madison DV TI - The Calumet County, Wisconsin, Leptospirae survey. LA - Eng MH - Agglutination Tests/methods MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Wisconsin PT - JOURNAL ARTICLE DA - 770315 DP - 1973 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 621-3 CY - UNITED STATES IP - 77 JC - PY5 EM - 7705 RO - M:CNR PMID- 4534740 LR - 930405 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1973;(77):621-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 77102877 AU - Tripathy DN AU - Hanson LE AU - Mansfield ME TI - Growth inhibition test for measurement of immune response of animals vaccinated with leptospiral bacterins. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - *Antibody Formation MH - *Bacterial Vaccines MH - Cattle/*immunology MH - Leptospira/growth & development/*immunology MH - Swine/*immunology PT - JOURNAL ARTICLE DA - 770315 DP - 1973 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 113-8 CY - UNITED STATES IP - 77 JC - PY5 EM - 7705 RO - M:CNR PMID- 4534706 LR - 930405 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1973;(77):113-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 73212535 AU - Hodges RT TI - A complement fixation test for the serological diagnosis of leptospirosis in pigs experimentally infected with serotype Pomona. LA - Eng MH - Agglutination Tests MH - Animal MH - Bacteriuria/veterinary MH - Complement Fixation Tests MH - Cross Reactions MH - Female MH - Leptospirosis/diagnosis/*veterinary MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 730910 DP - 1973 Jan-Feb IS - 0048-0169 TA - N Z Vet J PG - 1-6 CY - NEW ZEALAND IP - 1 VI - 21 JC - OBZ EM - 7310 PMID- 4515191 CU - 88 SO - N Z Vet J 1973 Jan-Feb;21(1):1-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] UI - 74093735 AU - Kalter SS TI - The baboon. Microbiology, clinical chemistry and some hematological aspects. LA - Eng MH - Adenoviridae/isolation & purification MH - Animal MH - Arboviruses/isolation & purification MH - Bacteria/isolation & purification MH - Candida albicans/isolation & purification MH - Conditioning (Psychology) MH - Fungi/isolation & purification MH - Haplorhini MH - Herpesviridae Infections/veterinary MH - Housing, Animal MH - Influenza/veterinary MH - Leptospirosis/veterinary MH - Meningitis/veterinary MH - Monkey Diseases MH - Mouth/microbiology MH - *Papio/classification MH - Picornaviridae/isolation & purification MH - Rectum/microbiology MH - Reoviridae Infections/veterinary MH - Rickettsia Infections/veterinary MH - Salmonella Infections, Animal MH - Skin/microbiology MH - Tuberculosis/veterinary MH - Virus Diseases/veterinary PT - JOURNAL ARTICLE DA - 740403 DP - 1973 IS - 0079-5119 TA - Primates Med PG - 1-171 CY - SWITZERLAND VI - 8 JC - PM6 EM - 7405 PMID- 4359841 CU - 93 SO - Primates Med 1973;8:1-171 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [115 medline neighbors] UI - 76225332 AU - Popova EM AU - Kindras TM TI - [The role of agricultural animals in the epidemiology of leptospiroses in the Leningrad region] LA - Rus MH - Agricultural Workers' Diseases/transmission MH - Animal MH - Human MH - Leptospirosis/*transmission/veterinary MH - Meat-Packing Industry MH - Occupational Diseases/*transmission MH - Russia PT - JOURNAL ARTICLE DA - 760901 DP - 1973 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 127-33 CY - USSR VI - 41 JC - VZR EM - 7610 PMID- 4283475 CU - 92 TT - Rol' sel'skokhoziaistvennykh zhivotnykh v epidemiologi leptospirozov v Leningradskoi oblasti SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1973;41:127-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 76225331 AU - Popova EM AU - Lesnikov AL AU - Iachmenev NI AU - Sil'ianova VI TI - [Epidemiologic features and clinico-laboratory characteristics of icterohemorrhagic and canicole leptospiroses in the North-West USSR] LA - Rus MH - Human MH - *Leptospira canicola MH - Leptospirosis/*epidemiology MH - Russia MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 760901 DP - 1973 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 121-6 CY - USSR VI - 41 JC - VZR EM - 7610 PMID- 4283474 CU - 92 TT - Epidemiologicheskie osobennosti i kliniko-laboratornaia kharakteristika ikterogemorragicheskogo i kanikola leptospirozov na Severo-Zapade SSSR SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1973;41:121-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 74148718 AU - Taghi-Zade TA TI - The search for potential additional sources of leptospiral infection on the territory of the Azerbaijan Soviet Socialist Republic. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antigens, Bacterial/isolation & purification MH - Anura MH - Azerbaijan MH - Birds MH - Chiropractic MH - *Disease Reservoirs MH - *Disease Vectors MH - Fresh Water MH - Kidney/microbiology MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*immunology MH - Reptiles PT - JOURNAL ARTICLE DA - 740620 DP - 1973 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 469-77 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 17 JC - IEV EM - 7408 PMID- 4274729 CU - 92 SO - J Hyg Epidemiol Microbiol Immunol 1973;17(4):469-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74009822 TI - [Indirect latex-leptospiral agglutination and inhibition test for the diagnosis of leptospirosis] LA - Chi MH - English Abstract MH - Human MH - *Latex Fixation Tests MH - Leptospira/immunology MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 731215 DP - 1973 IS - 0376-2491 TA - Chung Hua I Hsueh Tsa Chih PG - 487-9 CY - CHINA VI - 8 JC - CDG EM - 7401 RO - M:BDS PMID- 4200746 LR - 851001 CU - 91 NI - A SO - Chung Hua I Hsueh Tsa Chih 1973;8:487-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 75224065 AU - Stavri D AU - Nicolescu M TI - [Sodium citrate, chelating agent for calcium ions in Korthoff's medium for Leptospira cultures] LA - Fre MH - Calcium MH - Chelating Agents MH - *Citrates MH - Culture Media MH - English Abstract MH - Leptospira/*growth & development PT - JOURNAL ARTICLE DA - 751021 DP - 1972 Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 585-6 CY - ROMANIA IP - 4 SUPPL VI - 31 JC - 8EM EM - 7512 PMID- 4681056 TT - Le citrate de sodium alcoylant des ions de calcium en milieu de Korthoff pour la culture des Leptospires EA - A SO - Arch Roum Pathol Exp Microbiol 1972 Dec;31(4 SUPPL):585-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 73132535 AU - Torten M AU - Eliash Z AU - Lawrence D AU - Shenberg E TI - Crocidura russula, a hitherto unknown carrier of leptospires. LA - Eng MH - Animal MH - Disease Vectors MH - Ecology MH - Israel MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology MH - *Shrews PT - JOURNAL ARTICLE DA - 730502 DP - 1972 Dec IS - 0021-2180 TA - Isr J Med Sci PG - 1917-20 SB - M CY - ISRAEL IP - 12 VI - 8 JC - GY0 EM - 7306 PMID- 4655308 CU - 88 SO - Isr J Med Sci 1972 Dec;8(12):1917-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73067540 AU - Prokopcakova H AU - Poracka L AU - Pospisil R TI - [Leptospirosis in domestic animals] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Czechoslovakia MH - English Abstract MH - Leptospirosis/epidemiology/*veterinary MH - Swine MH - Swine Diseases/*epidemiology MH - Weil's Disease/epidemiology/veterinary PT - JOURNAL ARTICLE DA - 730228 DP - 1972 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 88-91 SB - M CY - USSR IP - 12 VI - 49 JC - Y9O EM - 7304 PMID- 4643657 CU - 89 TT - Leptospiroz u nekotorykh domashnikh zhivotnykh. SO - Zh Mikrobiol Epidemiol Immunobiol 1972 Dec;49(12):88-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73053802 AU - Hanson LE AU - Tripathy DN AU - Killinger AH TI - Current status of leptospirosis immunization in swine and cattle. LA - Eng MH - Abortion, Veterinary/prevention & control MH - Agglutination Tests MH - Animal MH - Bacterial Vaccines/administration & dosage MH - Cattle MH - Cattle Diseases/immunology/*prevention & control MH - Female MH - Immunization/*veterinary MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/prevention & control/*veterinary MH - Male MH - Pregnancy MH - Swine MH - Swine Diseases/immunology/*prevention & control PT - JOURNAL ARTICLE DA - 730205 DP - 1972 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1235-43 SB - M CY - UNITED STATES IP - 11 VI - 161 JC - HAV EM - 7303 PMID- 4638505 SO - J Am Vet Med Assoc 1972 Dec 1;161(11):1235-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73085517 AU - Carillo CG AU - Meyers DM AU - Szyfres B TI - Bataviae group leptospirae isolated from armadillos in Argentina. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/analysis MH - Argentina MH - Bacteriological Techniques MH - Cattle MH - Cattle Diseases/epidemiology MH - *Edentata MH - Kidney/microbiology MH - Leptospira/classification/immunology/*isolation & purification MH - Leptospirosis/diagnosis/microbiology/*veterinary MH - Serotyping PT - JOURNAL ARTICLE DA - 730321 DP - 1972 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 377-81 SB - M CY - NETHERLANDS IP - 4 VI - 24 JC - WGJ EM - 7305 PMID- 4567609 CU - 90 SO - Trop Geogr Med 1972 Dec;24(4):377-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 73062079 AU - Anderson LE AU - Jenkin HM TI - Estimation of leptospiral viability with agar pour plates. LA - Eng MH - *Agar MH - *Bacteriological Techniques MH - Culture Media MH - Leptospira/*growth & development MH - Leptospira canicola/growth & development MH - Leptospira interrogans/growth & development MH - Time Factors PT - JOURNAL ARTICLE DA - 730217 DP - 1972 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2587-92 SB - M CY - UNITED STATES IP - 12 VI - 33 JC - 40C EM - 7304 PMID- 4565729 CU - 90 SO - Am J Vet Res 1972 Dec;33(12):2587-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 73178217 AU - Imamura S AU - Matsui H AU - Ashizawa Y TI - Studies on indirect hemagglutination test for leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Bile Acids and Salts MH - Erythrocytes/immunology MH - *Hemagglutination Tests MH - Human MH - Immune Sera MH - Leptospirosis/diagnosis/*immunology MH - Rabbits/immunology MH - Sheep/immunology MH - Tannins PT - JOURNAL ARTICLE DA - 730711 DP - 1972 Dec IS - 0021-5031 TA - Jpn J Exp Med PG - 563-8 SB - M CY - JAPAN IP - 6 VI - 42 JC - KJR EM - 7308 PMID- 4540907 CU - 89 SO - Jpn J Exp Med 1972 Dec;42(6):563-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 73067520 AU - Vigovski AI TI - [Principal results of study of natural foci of infectious diseases in the Polish People's Republic (literature review)] LA - Rus MH - Animal MH - Birds MH - Brucellosis/*epidemiology MH - Brucellosis, Bovine/epidemiology MH - Cattle MH - Culicidae MH - Disease Vectors MH - Ecology MH - Encephalitis, Tick-Borne/*epidemiology MH - Fleas MH - Goats MH - Human MH - Leptospirosis/*epidemiology MH - Lice MH - Mice MH - Poland MH - Rats MH - Rodentia MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology MH - Ticks MH - Tularemia/*epidemiology PT - JOURNAL ARTICLE PT - REVIEW DA - 730228 DP - 1972 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 107-12 SB - M CY - USSR IP - 12 VI - 49 JC - Y9O EM - 7304 RF - 27 PMID- 4404960 CU - 94 TT - Osnovnye itogi izucheniia prirodnykh ochagov infektsionnykh boleznei v Bol'skoi Narodnoi Respublike (obzor literatury. SO - Zh Mikrobiol Epidemiol Immunobiol 1972 Dec;49(12):107-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [14 medline neighbors] UI - 73053812 AU - Woelffer EA TI - Diagnosis of bovine abortion. LA - Eng MH - Abortion, Veterinary/*diagnosis MH - Animal MH - Bovine Virus Diarrhea-Mucosal Disease/diagnosis MH - Brucellosis, Bovine/diagnosis MH - Cattle MH - Cattle Diseases/*diagnosis MH - Female MH - Herpesviridae Infections/diagnosis/veterinary MH - Infectious Bovine Rhinotracheitis MH - Leptospirosis/diagnosis/veterinary MH - Mycoses/diagnosis/veterinary MH - Pregnancy MH - Trichomonas Infections/diagnosis/veterinary MH - Vibrio Infections/diagnosis/veterinary PT - JOURNAL ARTICLE DA - 730205 DP - 1972 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1284-7 SB - M CY - UNITED STATES IP - 11 VI - 161 JC - HAV EM - 7303 PMID- 4344637 CU - 93 SO - J Am Vet Med Assoc 1972 Dec 1;161(11):1284-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 73053803 AU - Stalheim OH TI - Swine leptospirosis certification: a proposal. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial MH - Dihydrostreptomycin Sulfate/therapeutic use MH - Leptospira/immunology MH - Leptospirosis/drug therapy/immunology/prevention & control/*veterinary MH - Swine MH - Swine Diseases/drug therapy/immunology/*prevention & control MH - Vaccination PT - JOURNAL ARTICLE DA - 730205 DP - 1972 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1244-7 SB - M CY - UNITED STATES IP - 11 VI - 161 JC - HAV EM - 7303 PMID- 4118120 CU - 95 SO - J Am Vet Med Assoc 1972 Dec 1;161(11):1244-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 73085481 AU - Huisman J TI - [Zoonoses--an interesting group of diseases] LA - Dut MH - Animal MH - Ascariasis MH - Leptospirosis MH - Ornithosis MH - Rabies MH - Salmonella Infections MH - Toxocara MH - Toxoplasmosis MH - Zoonoses PT - JOURNAL ARTICLE DA - 730321 DP - 1972 Nov 21 TA - Tijdschr Ziekenverpl PG - 1215-21 SB - N CY - NETHERLANDS IP - 37 VI - 25 JC - VS3 EM - 7305 PMID- 4486519 CU - 89 LI - N TT - Zoonosen--een interessante groep ziekten. SO - Tijdschr Ziekenverpl 1972 Nov 21;25(37):1215-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73025420 AU - Michna SW AU - Ellis W TI - Leptospirosis. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Great Britain MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 730102 DP - 1972 Nov 11 IS - 0140-6736 TA - Lancet PG - 1036-7 SB - A SB - M CY - ENGLAND IP - 785 VI - 2 JC - L0S EM - 7302 PMID- 4116973 CU - 95 SO - Lancet 1972 Nov 11;2(785):1036-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 73057166 AU - Jannuzzi C TI - [Clinical manifestations of fetal infections in the newborn infant. Infections due to schizomycetes] LA - Ita MH - Bacterial Infections/*diagnosis MH - Campylobacter fetus/isolation & purification MH - Female MH - Fetal Diseases/*complications MH - Human MH - Infant, Newborn MH - Infant, Newborn, Diseases/*etiology MH - Leptospirosis/diagnosis MH - Listeria Infections/diagnosis MH - Mycobacterium tuberculosis/isolation & purification MH - Mycoplasma/isolation & purification MH - Pregnancy MH - Rickettsia/isolation & purification MH - Spirochaetales Infections/diagnosis MH - Tuberculosis/diagnosis PT - JOURNAL ARTICLE DA - 730208 DP - 1972 Nov 3 IS - 0026-4946 TA - Minerva Pediatr PG - 1886-904 CY - ITALY IP - 38 VI - 24 JC - NAM EM - 7303 PMID- 4629593 CU - 91 TT - Le manifestazioni cliniche delle infezioni fetali nel neonato. Infezioni da schizomiceti. SO - Minerva Pediatr 1972 Nov 3;24(38):1886-904 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 73028612 AU - Crawford RP TI - Identification of the immunoglobulins in serums of guinea pigs infected with serogroup Pomona Leptospires. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial MH - Antigens, Bacterial MH - Centrifugation, Density Gradient MH - Chromatography MH - Chromatography, Ion Exchange MH - Guinea Pigs/*immunology MH - IgM/isolation & purification MH - Immunoelectrophoresis MH - Immunoglobulins/*isolation & purification MH - Leptospira/immunology MH - Leptospirosis/immunology/*veterinary MH - Mercaptoethanol/pharmacology MH - Methods MH - Precipitation MH - Rodent Diseases/*immunology MH - Ultracentrifugation PT - JOURNAL ARTICLE DA - 730103 DP - 1972 Nov IS - 0002-9645 TA - Am J Vet Res PG - 2289-98 SB - M CY - UNITED STATES IP - 11 VI - 33 JC - 40C EM - 7302 PMID- 5081488 CU - 90 SO - Am J Vet Res 1972 Nov;33(11):2289-98 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74033264 AU - Azarian RP TI - [Blood indices of sows in leptospirosis (experimental data)] LA - Rus MH - Animal MH - Female MH - Lactation MH - Leptospirosis/blood/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*blood PT - JOURNAL ARTICLE DA - 740118 DP - 1972 Nov IS - 0042-4846 TA - Veterinariia PG - 62-3 CY - USSR VI - 11 JC - XCC EM - 7402 PMID- 4668220 TT - Pokazateli krovi u svinomatok pri leptospiroze (eksperimental'nye dannye. SO - Veterinariia 1972 Nov;11:62-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 73215246 AU - Mason RW AU - King SJ AU - McLachlan NM TI - Suspected leptospirosis in two cats. LA - Eng MH - Animal MH - *Cat Diseases/immunology/pathology MH - Cats MH - Leptospira/immunology MH - Leptospirosis/immunology/pathology/*veterinary MH - Nephritis, Interstitial/immunology/pathology/veterinary PT - JOURNAL ARTICLE DA - 730912 DP - 1972 Nov IS - 0005-0423 TA - Aust Vet J PG - 622-3 SB - M CY - AUSTRALIA IP - 11 VI - 48 JC - 9IE EM - 7310 PMID- 4664366 SO - Aust Vet J 1972 Nov;48(11):622-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 73073725 AU - Valova GP AU - Mefod'ev VV TI - [Specific features of an epidemic process in leptospiroses in northern conditions in Western Siberia] LA - Rus MH - Animal MH - Bird Diseases/epidemiology MH - Birds MH - Carnivora MH - Cattle MH - Cattle Diseases/epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - Ecology MH - English Abstract MH - Foxes MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - Insectivora MH - Leptospirosis/*epidemiology/veterinary MH - Mice MH - Rats MH - Reindeer MH - Rodent Diseases/epidemiology MH - Rodentia MH - Sheep MH - Sheep Diseases/epidemiology MH - Siberia PT - JOURNAL ARTICLE DA - 730305 DP - 1972 Nov TA - Zh Mikrobiol Epidemiol Immunobiol PG - 138-45 SB - M CY - USSR IP - 11 VI - 49 JC - Y9O EM - 7304 PMID- 4645851 CU - 89 TT - Nekotorye spetsificheskie cherty epidemicheskogo protsessa pri leptospirozakh v usloviiakh Severa v Zapadnoi Sibiri. SO - Zh Mikrobiol Epidemiol Immunobiol 1972 Nov;49(11):138-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73150406 AU - Takashima I AU - Yanagawa R TI - Isolation and characterization of streptomycin-resistant mutant of leptospiras. LA - Eng MH - Agglutination Tests MH - *Drug Resistance, Microbial MH - Immunodiffusion MH - Leptospira/drug effects/*isolation & purification MH - Leptospira interrogans/drug effects/isolation & purification MH - *Mutation MH - Streptomycin/*pharmacology PT - JOURNAL ARTICLE DA - 730606 DP - 1972 Nov IS - 0021-5139 TA - Jpn J Microbiol PG - 535-7 SB - M CY - JAPAN IP - 6 VI - 16 JC - KMF EM - 7307 PMID- 4632984 CU - 91 SO - Jpn J Microbiol 1972 Nov;16(6):535-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73043432 AU - Babudieri B TI - Systematics of a leptospira strain isolated from frog. LA - Eng MH - Animal MH - Anura MH - Gerbillinae MH - Guinea Pigs MH - Hamsters MH - Leptospira/classification/*isolation & purification/pathogenicity MH - Mice MH - *Rana pipiens MH - Serotyping PT - JOURNAL ARTICLE DA - 730118 DP - 1972 Oct 15 IS - 0014-4754 TA - Experientia PG - 1252-3 SB - M CY - SWITZERLAND IP - 10 VI - 28 JC - EQZ EM - 7303 PMID- 4538985 CU - 89 SO - Experientia 1972 Oct 15;28(10):1252-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 73193181 AU - Kirpichev AF TI - [High antibody teters in Leptospira-infected animals] LA - Rus MH - Animal MH - Antibodies/*analysis MH - *Antibody Formation MH - Leptospirosis/immunology/*veterinary MH - Sheep MH - Sheep Diseases/immunology PT - JOURNAL ARTICLE DA - 730809 DP - 1972 Oct IS - 0042-4846 TA - Veterinariia PG - 63-4 CY - USSR VI - 10 JC - XCC EM - 7309 PMID- 4676948 CU - 85 TT - Vysota titrov antitel u zarazhennykh leptospirami zhivotnykh. SO - Veterinariia 1972 Oct;10:63-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 73136971 AU - Straton C AU - Bercovici C AU - Straton A AU - Radulescu P TI - [Study of the primary natural reservoir of Leptospira in the valley of the Prut. II. The middle and upper basin of the Prut] LA - Rum MH - Animal MH - Antibodies/analysis MH - Cattle MH - Cattle Diseases/epidemiology MH - *Disease Reservoirs MH - English Abstract MH - Leptospira/isolation & purification MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Mice MH - Rodent Diseases/epidemiology MH - Romania MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 730504 DP - 1972 Oct-Dec IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 977-84 CY - ROMANIA IP - 4 VI - 76 JC - SHP EM - 7306 PMID- 4676326 CU - 88 TT - Studiul rezervorului natural primar de leptospire in valea Prutului. II. Bazinul mijlociu si superior al Prutului. SO - Rev Med Chir Soc Med Nat Iasi 1972 Oct-Dec;76(4):977-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 73088746 AU - Stallmann ND TI - The isolation of a strain of Leptospira, serotype hardjo, from a patient in Southern Queensland. LA - Eng MH - Animal MH - Case Report MH - Cattle MH - Cattle Diseases/microbiology MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*microbiology MH - Male MH - Serotyping PT - JOURNAL ARTICLE DA - 730328 DP - 1972 Oct IS - 0005-0423 TA - Aust Vet J PG - 576 SB - M CY - AUSTRALIA IP - 10 VI - 48 JC - 9IE EM - 7305 PMID- 4675326 CU - 85 SO - Aust Vet J 1972 Oct;48(10):576 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 73081446 AU - Brandis U TI - [Leptospirosis imported from Spain] LA - Ger MH - Germany, West MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Spain PT - JOURNAL ARTICLE DA - 730313 DP - 1972 Oct IS - 0025-8474 TA - Med Monatsschr PG - 470-1 CY - GERMANY, WEST IP - 10 VI - 26 JC - M5E EM - 7305 PMID- 4647532 CU - 88 TT - Eine aus Spanien eingeschleppte Leptospirose. SO - Med Monatsschr 1972 Oct;26(10):470-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 73044583 AU - Fennestad KL AU - Borg-Petersen C TI - Leptospirosis in Danish wild mammals. LA - Eng MH - Animal MH - Carnivora MH - Cattle MH - Cattle Diseases/epidemiology MH - Chiroptera MH - Deer MH - Denmark MH - Dog Diseases/epidemiology MH - Dogs MH - Ecology MH - Hedgehogs MH - Human MH - Leptospirosis/epidemiology/*veterinary MH - Mice MH - Rabbits MH - Rats MH - Rodent Diseases/epidemiology MH - Sciuridae MH - Shrews MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE PT - REVIEW DA - 730129 DP - 1972 Oct IS - 0090-3558 TA - J Wildl Dis PG - 343-51 SB - M CY - UNITED STATES IP - 4 VI - 8 JC - KEM EM - 7303 RF - 14 PMID- 4564183 CU - 90 SO - J Wildl Dis 1972 Oct;8(4):343-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 73033354 AU - Mefod'ev VV AU - Valova GP TI - [Motive factors of an epidemic process in leptospiroses in Western Siberia (review of the literature)] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - English Abstract MH - Goats MH - Hamsters MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Reindeer MH - Rodent Diseases/epidemiology MH - Rodentia MH - Sheep MH - Sheep Diseases/epidemiology MH - Siberia MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE PT - REVIEW DA - 730105 DP - 1972 Oct TA - Zh Mikrobiol Epidemiol Immunobiol PG - 87-91 SB - M CY - USSR IP - 10 VI - 49 JC - Y9O EM - 7302 RF - 19 PMID- 4563426 CU - 90 TT - Dvizhushchie faktory epidemicheskogo protsessa pri leptospirozakk v Zapadnoi Sibiri (obzor literatury. SO - Zh Mikrobiol Epidemiol Immunobiol 1972 Oct;49(10):87-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 73026284 AU - Steele JH TI - Environmental health and animal wastes. LA - Eng MH - Animal MH - Anthrax/etiology/veterinary MH - Brucellosis/etiology MH - Brucellosis, Bovine/etiology MH - Cattle MH - *Environmental Health MH - Escherichia coli Infections/etiology/veterinary MH - *Feces MH - Human MH - Leptospirosis/etiology/veterinary MH - Poultry MH - Refuse Disposal MH - Salmonella Infections/etiology MH - Salmonella Infections, Animal/etiology MH - Tuberculosis, Avian/etiology MH - Tuberculosis, Bovine/etiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 730102 DP - 1972 Oct IS - 0026-8542 TA - Mod Vet Pract PG - 25-9 SB - M CY - UNITED STATES IP - 11 VI - 53 JC - NGO EM - 7302 PMID- 4562722 CU - 90 SO - Mod Vet Pract 1972 Oct;53(11):25-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [127 medline neighbors] UI - 73011596 AU - Birnbaum S AU - Shenberg E AU - Torten M TI - The influence of maternal antibodies on the epidemiology of leptospiral carrier state in mice. LA - Eng MH - Agglutination Tests MH - Animal MH - Animals, Newborn MH - Antibodies/analysis MH - Bacteriological Techniques MH - Carrier State/*immunology MH - Female MH - *Immunity, Maternally-Acquired MH - Kidney/microbiology MH - Lactation MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*immunology/microbiology MH - *Maternal-Fetal Exchange MH - Mice MH - Milk/immunology MH - Pregnancy PT - JOURNAL ARTICLE DA - 721125 DP - 1972 Oct IS - 0002-9262 TA - Am J Epidemiol PG - 313-7 SB - M CY - UNITED STATES IP - 4 VI - 96 JC - 3H3 EM - 7301 PMID- 4561515 CU - 90 SO - Am J Epidemiol 1972 Oct;96(4):313-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 72270467 TI - Leptospirosis. LA - Eng MH - Animal MH - Animal Diseases MH - Cattle MH - Cattle Diseases MH - Complement Fixation Tests MH - *Disease Vectors MH - Dog Diseases MH - Dogs MH - Great Britain MH - Hedgehogs MH - Human MH - Leptospira MH - *Leptospirosis MH - Mice MH - Rats MH - Serotyping MH - Sheep MH - Sheep Diseases MH - Shrews MH - Swine MH - Swine Diseases PT - JOURNAL ARTICLE DA - 721030 DP - 1972 Sep 30 IS - 0140-6736 TA - Lancet PG - 694-5 SB - A SB - M CY - ENGLAND IP - 779 VI - 2 JC - L0S EM - 7212 PMID- 4115829 CU - 95 NI - A SO - Lancet 1972 Sep 30;2(779):694-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73123204 AU - Kiktenko VS TI - [Natural reservoirs and foci of leptospirosis] LA - Rus MH - Animal MH - Buffaloes MH - Carrier State/*veterinary MH - Cat Diseases/epidemiology MH - Cats MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Reservoirs/*veterinary MH - Dog Diseases/epidemiology MH - Dogs MH - English Abstract MH - Foxes MH - Horse Diseases/epidemiology MH - Horses MH - Insectivora MH - Leptospirosis/epidemiology/*veterinary MH - Rodent Diseases/epidemiology MH - Rodentia MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 730416 DP - 1972 Sep TA - Zh Mikrobiol Epidemiol Immunobiol PG - 106-10 SB - M CY - USSR IP - 9 VI - 49 JC - Y9O EM - 7306 PMID- 4653078 CU - 89 TT - O rezervuarakh i ochagakh leptospiroznoi infektsii v prirode. SO - Zh Mikrobiol Epidemiol Immunobiol 1972 Sep;49(9):106-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 73093709 AU - Baird JD AU - Williams T AU - Claxton PD TI - A premature birth associated with Leptospira pomona infection in a mare. LA - Eng MH - Abortion, Veterinary MH - Agglutination Tests MH - Animal MH - Animals, Newborn MH - Disease Outbreaks/veterinary MH - Female MH - Fetal Death/veterinary MH - *Horse Diseases MH - Horses MH - Labor, Premature/*veterinary MH - Leptospirosis/etiology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/*veterinary MH - Sewage MH - Swine MH - Swine Diseases PT - JOURNAL ARTICLE DA - 730403 DP - 1972 Sep IS - 0005-0423 TA - Aust Vet J PG - 524-6 SB - M CY - AUSTRALIA IP - 9 VI - 48 JC - 9IE EM - 7305 PMID- 4651124 SO - Aust Vet J 1972 Sep;48(9):524-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 73074549 AU - Amato Neto V AU - Tcherniacovski I AU - Baldy JL TI - [Interstitial pneumonia caused by leptospirosis: report of a case] LA - Por MH - Adolescence MH - Case Report MH - English Abstract MH - Human MH - Leptospirosis/*complications MH - Male MH - Pulmonary Fibrosis/*etiology PT - JOURNAL ARTICLE DA - 730307 DP - 1972 Sep-Oct IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 334-7 CY - BRAZIL IP - 5 VI - 14 JC - S9D EM - 7304 PMID- 4646009 TT - Pneumonia intersticial devida a leptospirose: relato de um caso. SO - Rev Inst Med Trop Sao Paulo 1972 Sep-Oct;14(5):334-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73051603 AU - Taniyama T AU - Yanagihara Y AU - Mifuchi I AU - Azuma I AU - Yamamura Y TI - Purification of polysaccharide antigen from Leptospira biflexa strain Urawa. LA - Eng MH - Amino Acids/analysis MH - Antigens, Bacterial/*isolation & purification MH - Bacterial Proteins/analysis MH - Carbohydrates/analysis MH - Chromatography, Gas MH - Leptospira/analysis/*immunology MH - Polysaccharides, Bacterial/*isolation & purification PT - JOURNAL ARTICLE DA - 730202 DP - 1972 Sep IS - 0019-9567 TA - Infect Immun PG - 414-5 SB - M CY - UNITED STATES IP - 3 VI - 6 JC - GO7 EM - 7303 PMID- 4637612 SO - Infect Immun 1972 Sep;6(3):414-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 73003537 AU - Arvidsson S AU - Hallgren J AU - Linder B AU - Snygg AC TI - [Leptospirosis--a topical case of Weil's disease] LA - Swe MH - Animal MH - Antibiotics/therapeutic use MH - Cattle MH - Cattle Diseases MH - Disease Reservoirs MH - Disease Vectors MH - Dog Diseases MH - Dogs MH - English Abstract MH - Human MH - Leptospira interrogans/isolation & purification MH - Male MH - Middle Age MH - Rats MH - Rodent Diseases MH - Scandinavia MH - Swine MH - Swine Diseases MH - *Weil's Disease PT - JOURNAL ARTICLE DA - 721115 DP - 1972 Aug 16 IS - 0023-7205 TA - Lakartidningen PG - 3824-30 CY - SWEDEN IP - 34 VI - 69 JC - L0N EM - 7301 PMID- 5070385 TT - Leptospiros--ett aktuellt fall av Weils sjukdom. SO - Lakartidningen 1972 Aug 16;69(34):3824-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 72242026 AU - Tripathy DN AU - Hanson LE TI - Colonial and morphologic variations of Leptospira illini strain 3055. LA - Eng MH - Animal MH - Culture Media MH - Leptospira/*cytology/growth & development/immunology PT - JOURNAL ARTICLE DA - 720921 DP - 1972 Aug IS - 0002-9645 TA - Am J Vet Res PG - 1723-7 SB - M CY - UNITED STATES IP - 8 VI - 33 JC - 40C EM - 7211 PMID- 5047125 SO - Am J Vet Res 1972 Aug;33(8):1723-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 72242025 AU - Santa Rosa CA AU - Sulzer CR AU - Pestana de Castro AF TI - A new leptospiral serotype in the bataviae group, isolated in Sao Paulo, Brazil. LA - Eng MH - Agglutination Tests MH - Animal MH - Brazil MH - Kidney MH - Leptospira/classification/immunology/*isolation & purification MH - Opossums MH - Serotyping MH - Tissue Culture PT - JOURNAL ARTICLE DA - 720921 DP - 1972 Aug IS - 0002-9645 TA - Am J Vet Res PG - 1719-21 SB - M CY - UNITED STATES IP - 8 VI - 33 JC - 40C EM - 7211 PMID- 5047124 SO - Am J Vet Res 1972 Aug;33(8):1719-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 73040966 AU - Varfolomeeva AA AU - Koval'skii GN TI - [Basic patterns in the epidemiologic process of leptospirosis under present conditions] LA - Rus MH - Agricultural Workers' Diseases/epidemiology MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Outbreaks/epidemiology MH - English Abstract MH - History of Medicine, 20th Cent. MH - Human MH - Leptospirosis/*epidemiology/etiology/history/veterinary MH - Meat-Packing Industry MH - Occupational Diseases/epidemiology MH - Seasons MH - USSR PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 730116 DP - 1972 Aug TA - Zh Mikrobiol Epidemiol Immunobiol PG - 86-92 SB - M CY - USSR IP - 8 VI - 49 JC - Y9O EM - 7303 PMID- 4563839 CU - 90 TT - Osnovnye zakonomernosti epidemicheskogo protsessa pri leptospirozakh v sovremennykh usloviiakh. SO - Zh Mikrobiol Epidemiol Immunobiol 1972 Aug;49(8):86-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 73225835 AU - Kmety E TI - [A Vi antigen in Leptospirae] LA - Ger MH - Absorption MH - Agglutination Tests MH - Antibody Formation MH - Antigens, Bacterial/*analysis MH - English Abstract MH - Epitopes MH - Human MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Nomenclature MH - Salmonella typhi/immunology MH - Serotyping MH - Species Specificity MH - Weil's Disease/immunology PT - JOURNAL ARTICLE DA - 731002 DP - 1972 Aug IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 343-51 SB - M CY - GERMANY, WEST IP - 3 VI - 221 JC - Y52 EM - 7311 PMID- 4124476 CU - 95 TT - Uber ein Vi-Antigen bei Leptospiren. SO - Zentralbl Bakteriol [Orig A] 1972 Aug;221(3):343-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 73009618 AU - Graham-Jones O TI - Man bites dog. LA - Eng MH - *Agricultural Workers' Diseases MH - Animal MH - Anthrax MH - Bacterial Infections MH - Brucellosis MH - Cats MH - Cattle MH - Dogs MH - Human MH - Intestinal Diseases MH - Leptospirosis MH - Mycoses MH - Pasteurella Infections MH - Rats MH - Tetanus MH - *Zoonoses PT - JOURNAL ARTICLE DA - 721118 DP - 1972 Jul 29 IS - 0042-4900 TA - Vet Rec PG - 115-7 SB - M CY - ENGLAND IP - 5 VI - 91 JC - XBS EM - 7301 PMID- 5073601 SO - Vet Rec 1972 Jul 29;91(5):115-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 72225136 TI - Leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Child, Preschool MH - Female MH - Great Britain MH - Human MH - Infant MH - Ireland MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 720905 DP - 1972 Jul 15 IS - 0007-1447 TA - Br Med J PG - 186-7 SB - A SB - M CY - ENGLAND IP - 819 VI - 3 JC - B4W EM - 7211 PMID- 5039799 CU - 88 NI - A SO - Br Med J 1972 Jul 15;3(819):186-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 72253094 AU - Maronpot RR AU - Barsoum IS TI - Leptospiral microscopic agglutinating antibodies in sera of man and domestic animals in Egypt. LA - Eng MH - Agglutination Tests MH - Animal MH - Animal Diseases/immunology MH - *Antibodies MH - Buffaloes MH - Camels MH - Cattle MH - Cattle Diseases/immunology MH - Egypt MH - Goats MH - Human MH - Leptospirosis/*immunology MH - Sheep MH - Sheep Diseases/immunology MH - Swine MH - Swine Diseases/immunology PT - JOURNAL ARTICLE DA - 720930 DP - 1972 Jul IS - 0002-9637 TA - Am J Trop Med Hyg PG - 467-72 SB - A SB - M CY - UNITED STATES IP - 4 VI - 21 JC - 3ZQ EM - 7212 PMID- 5065696 CU - 85 SO - Am J Trop Med Hyg 1972 Jul;21(4):467-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 72220153 AU - Crawford RP TI - Molecular characteristics of antibody detected by the microscopic agglutination test in serum of guinea pigs with leptospirosis. LA - Eng MH - Agglutination Tests/*veterinary MH - Animal MH - Antibodies/*isolation & purification MH - Centrifugation, Density Gradient MH - Chromatography MH - Female MH - *Guinea Pigs MH - IgG/isolation & purification MH - IgM/isolation & purification MH - Immunoglobulins/isolation & purification MH - Leptospira/immunology MH - Leptospirosis/immunology/*veterinary MH - Male MH - Mercaptoethanol/pharmacology MH - Methods MH - Rodent Diseases/*immunology MH - Ultracentrifugation PT - JOURNAL ARTICLE DA - 720828 DP - 1972 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1507-12 SB - M CY - UNITED STATES IP - 7 VI - 33 JC - 40C EM - 7210 PMID- 5039521 CU - 90 SO - Am J Vet Res 1972 Jul;33(7):1507-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 73055817 AU - Tomita K AU - Maki S AU - Shimotsuji T AU - Iida H AU - Seino Y TI - [Case of Weil's disease with Leptospira isolated from the blood and urine] LA - Jpn MH - Blood/microbiology MH - Child MH - Human MH - Leptospira/*isolation & purification MH - Male MH - Urine/microbiology MH - Weil's Disease/*microbiology PT - JOURNAL ARTICLE DA - 730208 DP - 1972 Jul IS - 0047-1852 TA - Nippon Rinsho PG - 1592-9 CY - JAPAN IP - 7 VI - 30 JC - KIM EM - 7303 PMID- 4674196 CU - 85 SO - Nippon Rinsho 1972 Jul;30(7):1592-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 73027363 AU - Schonberger W AU - Emmrich P AU - Jost R AU - Schonberger G AU - Straub E AU - Engelhardt K TI - [Lymphadenitis of the neck in childhood caused by Leptospira] LA - Ger MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Infant MH - Leptospira/immunology MH - Leptospirosis/*complications/pathology MH - Leukocytosis/etiology MH - Lymphadenitis/blood/*etiology/immunology/pathology MH - Male MH - Neck PT - JOURNAL ARTICLE DA - 730103 DP - 1972 Jul IS - 0300-8630 TA - Klin Padiatr PG - 276-82 SB - M CY - GERMANY, WEST IP - 4 VI - 184 JC - KWE EM - 7302 PMID- 4673160 CU - 85 TT - Lymphadenitis colli durch Leptospiren im Kindesalter. SO - Klin Padiatr 1972 Jul;184(4):276-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74113921 AU - Babudieri B AU - Nabavi F TI - Asymmetric cross-reactions in water leptospiras. LA - Eng MH - Antigens/analysis MH - *Cross Reactions MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 740502 DP - 1972 Jul-Aug IS - 0021-2547 TA - Boll Ist Sieroter Milan PG - 289-91 SB - M CY - ITALY IP - 4 VI - 51 JC - AKG EM - 7406 PMID- 4669697 SO - Boll Ist Sieroter Milan 1972 Jul-Aug;51(4):289-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 73240933 AU - Genis AI TI - [Small mammals as carriers of leptospirosis] LA - Rus MH - Animal MH - Carrier State/*microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/*microbiology MH - *Mammals PT - JOURNAL ARTICLE DA - 731025 DP - 1972 Jul IS - 0042-4846 TA - Veterinariia PG - 69 CY - USSR VI - 7 JC - XCC EM - 7312 PMID- 4666158 TT - Melkie mlekopitaiushchie--nositeli leptospiroza. SO - Veterinariia 1972 Jul;7:69 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 73133149 AU - Sullivan ND TI - Further observations on Leptospira hardjo infections in pregnant cows. LA - Eng MH - Abortion, Veterinary/etiology MH - Agglutination Tests MH - Animal MH - Bacteriuria/veterinary MH - Cattle MH - *Cattle Diseases MH - Cross Infection/veterinary MH - Female MH - Leptospira/pathogenicity MH - Leptospirosis/diagnosis/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/*veterinary PT - JOURNAL ARTICLE DA - 730503 DP - 1972 Jul IS - 0005-0423 TA - Aust Vet J PG - 388-90 SB - M CY - AUSTRALIA IP - 7 VI - 48 JC - 9IE EM - 7306 PMID- 4655384 SO - Aust Vet J 1972 Jul;48(7):388-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 73060927 AU - Kadlec V TI - [Immunogenic relation between genus Brucella and Leptospira in the blood serum of pigs and cattle] LA - Cze MH - Agglutination Tests MH - Animal MH - Antibody Formation MH - Brucella/*immunology MH - Brucellosis, Bovine/diagnosis MH - Cattle MH - Cattle Diseases/*immunology MH - English Abstract MH - Leptospira/*immunology MH - Leptospirosis/veterinary MH - Serodiagnosis MH - Swine MH - Swine Diseases/*immunology PT - JOURNAL ARTICLE DA - 730215 DP - 1972 Jul IS - 0375-8427 TA - Vet Med (Praha) PG - 413-6 SB - M CY - CZECHOSLOVAKIA IP - 7 VI - 17 JC - XBP EM - 7304 PMID- 4629679 CU - 91 TT - Imunogenni vztah mezi rodem Brucella a Leptospira v krevnim seru prasat a skotu. SO - Vet Med (Praha) 1972 Jul;17(7):413-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [29 medline neighbors] UI - 72212301 AU - Knight AP AU - Pierson RE AU - Hoerlein AB AU - Collier JH AU - Horton DP AU - Pruett JB TI - Effect of vaccination time on morbidity, mortality, and weight gains of feeder calves. LA - Eng MH - Animal MH - Body Weight MH - Cattle/growth & development MH - Cattle Diseases/*prevention & control MH - Edema/prevention & control/veterinary MH - Female MH - Herpesviridae Infections/prevention & control/veterinary MH - Herpesvirus 1, Bovine MH - Immunization Schedule/veterinary MH - Leptospirosis/prevention & control/veterinary MH - Male MH - Paramyxoviridae Infections/prevention & control/veterinary MH - Pasteurella Infections/prevention & control/veterinary MH - Time Factors MH - Vaccination/*veterinary MH - Weaning PT - JOURNAL ARTICLE DA - 720819 DP - 1972 Jul IS - 0003-1488 TA - J Am Vet Med Assoc PG - 45-8 SB - M CY - UNITED STATES IP - 1 VI - 161 JC - HAV EM - 7210 PMID- 4338559 CU - 96 SO - J Am Vet Med Assoc 1972 Jul;161(1):45-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 73029194 AU - Guthenke D AU - Kokles R TI - [Serological tests on hare blood samples for antibodies of leptospirosis, brucellosis, Aujeszky's disease, and mucosal disease] LA - Ger MH - Animal MH - Antibodies/*analysis MH - Brucellosis/diagnosis/veterinary MH - Communicable Diseases/diagnosis/*veterinary MH - English Abstract MH - Leptospirosis/diagnosis/veterinary MH - Pseudorabies/diagnosis MH - *Rabbits MH - Serodiagnosis/veterinary PT - JOURNAL ARTICLE DA - 730103 DP - 1972 Jun 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 465-8 CY - GERMANY, EAST IP - 12 VI - 27 JC - NGV EM - 7302 PMID- 5081756 CU - 84 TT - Serologische Untersuchungen an Hasenblutproben auf Leptospirose-, Brucellose-, Aujeszky- ung Mucosal-Disease-Antikoper. SO - Monatsh Veterinarmed 1972 Jun 15;27(12):465-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 73031264 AU - Arambulo PV 3d AU - Topacio TM Jr AU - Famatiga EG AU - Sarmiento RV AU - Lopez S TI - Leptospirosis among abattoir employees, dog pound workers, and fish inspectors in the city of Manila. LA - Eng MH - *Abattoirs MH - Adolescence MH - Adult MH - Agglutination Tests MH - Animal MH - Antigens/isolation & purification MH - Dogs MH - Female MH - *Fish Products MH - *Food Inspection MH - Human MH - Leptospira/immunology MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Occupational Diseases/*epidemiology/immunology MH - Philippines MH - Zoonoses PT - JOURNAL ARTICLE DA - 730103 DP - 1972 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 212-20 SB - M CY - THAILAND IP - 2 VI - 3 JC - UVN EM - 7302 PMID- 5082849 CU - 88 SO - Southeast Asian J Trop Med Public Health 1972 Jun;3(2):212-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 73031263 AU - Tan DS AU - Lopes DA TI - A preliminary study of the status of leptospirosis in the Malaysian Armed forces. LA - Eng MH - Antibodies/isolation & purification MH - Human MH - Leptospirosis/*epidemiology/immunology MH - Malaysia MH - Male MH - *Military Medicine PT - JOURNAL ARTICLE DA - 730103 DP - 1972 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 208-11 SB - M CY - THAILAND IP - 2 VI - 3 JC - UVN EM - 7302 PMID- 5082848 CU - 88 SO - Southeast Asian J Trop Med Public Health 1972 Jun;3(2):208-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 73031262 AU - Welsh JD AU - Sulzer CR AU - Douglas HL TI - Leptospiral seroreactors in the Mekong Delta of South Vietnam. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Antigens/isolation & purification MH - Child MH - Child, Preschool MH - Female MH - Human MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Vietnam PT - JOURNAL ARTICLE DA - 730103 DP - 1972 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 205-7 SB - M CY - THAILAND IP - 2 VI - 3 JC - UVN EM - 7302 PMID- 5082847 CU - 88 SO - Southeast Asian J Trop Med Public Health 1972 Jun;3(2):205-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 72267213 AU - Herms G TI - [Bioptic histological findings in the liver in brucellosis and leptospirosis] LA - Ger MH - Adult MH - Animal MH - Biopsy MH - Brucellosis, Bovine/complications/*pathology MH - Cattle MH - English Abstract MH - Hepatitis/complications/pathology MH - Human MH - Leptospirosis/complications/*pathology MH - Liver/*pathology MH - Male PT - JOURNAL ARTICLE DA - 721020 DP - 1972 Jun 1 IS - 0044-2542 TA - Z Gesamte Inn Med PG - 474-7 SB - M CY - GERMANY, EAST IP - 11 VI - 27 JC - XUY EM - 7212 PMID- 5066433 CU - 85 TT - Bioptisch-histologische Befunde an der Leber bei Brucellose und Leptospirose. SO - Z Gesamte Inn Med 1972 Jun 1;27(11):474-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 72225637 AU - Lawson JH TI - Leptospirosis in the West of Scotland. LA - Eng MH - Abattoirs MH - Animal MH - Disease Reservoirs MH - Dogs MH - Human MH - Leptospira canicola MH - Leptospirosis/diagnosis/*epidemiology/microbiology MH - Meat MH - Occupational Diseases/epidemiology MH - Rats MH - Scotland MH - Serodiagnosis MH - Swine MH - Zoonoses PT - JOURNAL ARTICLE DA - 720905 DP - 1972 Jun IS - 0036-9330 TA - Scott Med J PG - 220-4 SB - M CY - SCOTLAND IP - 6 VI - 17 JC - UJK EM - 7211 PMID- 5064755 CU - 88 SO - Scott Med J 1972 Jun;17(6):220-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 72259749 AU - Mittermayer T AU - Plesko I AU - Hlavata Z TI - [1st case of Leptospirosis bulgarica on our territory] LA - Slo MH - Adult MH - Czechoslovakia MH - English Abstract MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/drug therapy/*epidemiology MH - Prednisone/therapeutic use MH - Streptomycin/therapeutic use MH - Tetracycline/therapeutic use PT - JOURNAL ARTICLE DA - 721006 DP - 1972 Jun IS - 0006-9248 TA - Bratisl Lek Listy PG - 717-9 CY - CZECHOSLOVAKIA IP - 6 VI - 57 JC - B5N EM - 7212 PMID- 5052890 CU - 88 TT - Prvy pripad Leptospirosis bulgarica na nasom uzemi. SO - Bratisl Lek Listy 1972 Jun;57(6):717-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 73142113 AU - Nicolescu M AU - Borsai L TI - The estimation of the results obtained by the complement fixation test performed with the Patoc antigen in the diagnosis of human leptospirosis. LA - Eng MH - Antibodies/*analysis MH - *Antigens MH - *Complement Fixation Tests MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*diagnosis MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 730515 DP - 1972 Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 209-16 CY - ROMANIA IP - 2 VI - 31 JC - 8EM EM - 7307 PMID- 4656457 SO - Arch Roum Pathol Exp Microbiol 1972 Jun;31(2):209-16 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [86 medline neighbors] UI - 73046647 AU - Auran NE AU - Johnson RC AU - Ritzi DM TI - Isolation of the outer sheath of Leptospira and its immunogenic properties in hamsters. LA - Eng MH - Animal MH - Antigens, Bacterial/administration & dosage MH - Centrifugation MH - Dialysis MH - Hamsters MH - Immunity MH - Immunization MH - Kidney/microbiology MH - *Leptospira canicola/analysis/cytology/drug effects/immunology/isolation & purification MH - Leptospirosis/*immunology MH - Microscopy, Electron MH - Sodium Chloride/pharmacology PT - JOURNAL ARTICLE DA - 730130 DP - 1972 Jun IS - 0019-9567 TA - Infect Immun PG - 968-75 SB - M CY - UNITED STATES IP - 6 VI - 5 JC - GO7 EM - 7303 PMID- 4635506 SO - Infect Immun 1972 Jun;5(6):968-75 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 73008675 AU - Twigg GI AU - Hughes DM AU - McDiarmid A TI - Leptospiral antibodies in dairy cattle: some ecological considerations. LA - Eng MH - Animal MH - *Antibodies, Bacterial MH - Cattle MH - Cattle Diseases/*immunology MH - Disease Reservoirs MH - *Ecology MH - Environment MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Mice MH - Rats MH - Soil MH - Water MH - Zoonoses PT - JOURNAL ARTICLE DA - 721116 DP - 1972 May 20 IS - 0042-4900 TA - Vet Rec PG - 598-602 SB - M CY - ENGLAND IP - 21 VI - 90 JC - XBS EM - 7301 PMID- 5073131 CU - 88 SO - Vet Rec 1972 May 20;90(21):598-602 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72227248 AU - Cinco M AU - Faidutti BM TI - Isolation and classification of water leptospira strains: identification of three new serotypes. LA - Eng MH - Italy MH - Leptospira/classification/*isolation & purification MH - Serotyping MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 720906 DP - 1972 May 15 IS - 0014-4754 TA - Experientia PG - 598-600 SB - M CY - SWITZERLAND IP - 5 VI - 28 JC - EQZ EM - 7211 PMID- 5040817 SO - Experientia 1972 May 15;28(5):598-600 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 72215185 AU - Sramkova L AU - Vanista J AU - Tesarova J AU - Cervova H AU - Karpenkova H TI - [Contribution to the serodiagnosis of leptospiroses] LA - Ger MH - *Agglutination Tests MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - Methods PT - JOURNAL ARTICLE DA - 720822 DP - 1972 May 4 IS - 0012-0219 TA - Dtsch Gesundheitsw PG - 859-64 CY - GERMANY, EAST IP - 18 VI - 27 JC - ECG EM - 7210 PMID- 5037377 CU - 90 TT - Beitrag zur serologischen Diagnostik der Leptospirosen. SO - Dtsch Gesundheitsw 1972 May 4;27(18):859-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 72183005 AU - Kobayashi Y AU - Kusaba T AU - Ueki R TI - Isolation of Leptospira javanica from rats on Ishigaki Island. LA - Eng MH - Agglutination Tests MH - Animal MH - Complement Fixation Tests MH - Cross Reactions MH - Guinea Pigs MH - Japan MH - Kidney/microbiology MH - Leptospira/immunology/*isolation & purification/pathogenicity MH - Leptospirosis/microbiology/*veterinary MH - Mice MH - *Rats MH - Rickettsia/immunology MH - Rodent Diseases/*microbiology MH - Spleen/microbiology PT - JOURNAL ARTICLE DA - 720720 DP - 1972 May IS - 0002-9637 TA - Am J Trop Med Hyg PG - 342-4 SB - A SB - M CY - UNITED STATES IP - 3 VI - 21 JC - 3ZQ EM - 7209 PMID- 5025619 SO - Am J Trop Med Hyg 1972 May;21(3):342-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 72183004 AU - Ooi BS AU - Chen BT AU - Tan KK AU - Khoo OT TI - Human renal leptospirosis. LA - Eng MH - Biopsy MH - Blood Urea Nitrogen MH - Creatinine/blood/urine MH - Electrolytes/blood MH - Follow-Up Studies MH - Human MH - Kidney/pathology MH - Kidney Failure, Acute/blood/*etiology/pathology/therapy/urine MH - Leptospirosis/*complications/drug therapy/pathology MH - Osmolar Concentration MH - Penicillin G/therapeutic use MH - Peritoneal Dialysis MH - Sodium/urine PT - JOURNAL ARTICLE DA - 720720 DP - 1972 May IS - 0002-9637 TA - Am J Trop Med Hyg PG - 336-41 SB - A SB - M CY - UNITED STATES IP - 3 VI - 21 JC - 3ZQ EM - 7209 PMID- 5025618 SO - Am J Trop Med Hyg 1972 May;21(3):336-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72169340 AU - Kondo E AU - Ueta N TI - Composition of fatty acids and carbohydrates in Leptospira. LA - Eng MH - Alcohol, Methyl MH - Amino Sugars/analysis MH - Carbohydrates/*analysis MH - Chloroform MH - Chromatography, Gas MH - Culture Media MH - Esters/analysis MH - Fatty Acids/*analysis MH - Fatty Acids, Essential/analysis MH - Glucosamine/analysis MH - Hexoses/analysis MH - Leptospira/*analysis/growth & development/pathogenicity MH - Leptospira canicola/analysis MH - Leptospira interrogans/analysis MH - Lipids/analysis MH - Monosaccharides/analysis MH - Nucleic Acids/analysis MH - Palmitic Acids/analysis MH - Pentoses/analysis MH - Polysaccharides, Bacterial/analysis MH - Solvents MH - Spectrum Analysis, Mass MH - Uronic Acids/analysis PT - JOURNAL ARTICLE DA - 720703 DP - 1972 May IS - 0021-9193 TA - J Bacteriol PG - 450-67 SB - M CY - UNITED STATES IP - 2 VI - 110 JC - HH3 EM - 7208 PMID- 5022167 CU - 90 SO - J Bacteriol 1972 May;110(2):450-67 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 73000209 AU - Hoare RJ AU - Claxton PD TI - Observations on Leptospira hardjo infection in New South Wales. LA - Eng MH - Abortion, Veterinary/*epidemiology MH - Animal MH - Australia MH - Cattle MH - Disease Outbreaks/*veterinary MH - Female MH - Leptospirosis/epidemiology/*veterinary MH - Mastitis, Bovine/*epidemiology/microbiology MH - Pregnancy PT - JOURNAL ARTICLE DA - 721108 DP - 1972 May IS - 0005-0423 TA - Aust Vet J PG - 228-32 SB - M CY - AUSTRALIA IP - 5 VI - 48 JC - 9IE EM - 7301 PMID- 4672114 CU - 88 SO - Aust Vet J 1972 May;48(5):228-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 73051557 AU - Alexander AD AU - Binn LN AU - Elisberg B AU - Husted P AU - Huxsoll DL AU - Marshall JD Jr AU - Needy CF AU - White AD TI - Zoonotic infections in military scout and tracker dogs in Vietnam. LA - Eng MH - Animal MH - Antibodies, Bacterial/analysis MH - Antibodies, Viral/analysis MH - Arbovirus Infections/epidemiology/veterinary MH - Dog Diseases/*epidemiology MH - Dogs MH - Fluorescent Antibody Technique MH - Hemagglutination Tests MH - Leptospirosis/epidemiology/veterinary MH - Melioidosis/epidemiology/veterinary MH - Military Medicine MH - Plague/epidemiology/veterinary MH - Rickettsia Infections/epidemiology/veterinary MH - Scrub Typhus/epidemiology/veterinary MH - Time Factors MH - Vietnam MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 730202 DP - 1972 May IS - 0019-9567 TA - Infect Immun PG - 745-9 SB - M CY - UNITED STATES IP - 5 VI - 5 JC - GO7 EM - 7303 PMID- 4564881 CU - 90 SO - Infect Immun 1972 May;5(5):745-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 72201960 AU - Johnson RC AU - Walby JK TI - Cultivation of leptospires: fatty acid requirements. LA - Eng MH - Bacteriological Techniques MH - Culture Media MH - Fatty Acids/*metabolism MH - Leptospira/*growth & development/metabolism/pathogenicity MH - Oleic Acids/metabolism MH - Palmitic Acids/metabolism MH - Serotyping MH - Stearic Acids/metabolism PT - JOURNAL ARTICLE DA - 720808 DP - 1972 May IS - 0003-6919 TA - Appl Microbiol PG - 1027-8 SB - M CY - UNITED STATES IP - 5 VI - 23 JC - 6K0 EM - 7210 PMID- 4555631 CU - 90 SO - Appl Microbiol 1972 May;23(5):1027-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [18 medline neighbors] UI - 72265283 AU - Richer D AU - Faye C AU - Camilleri JP TI - [Anatomoclinical study of a case of severe leptospirosis] LA - Fre MH - Blood Coagulation Disorders MH - Cholestasis/pathology MH - Endotoxins MH - English Abstract MH - Hepatitis/pathology MH - Human MH - Kidney/*pathology MH - Liver/*pathology MH - Male MH - Middle Age MH - Myocardium/pathology MH - Nephritis, Interstitial/pathology MH - Neurologic Manifestations MH - Shock, Septic MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 721019 DP - 1972 Apr 8 IS - 0037-1777 TA - Sem Hop PG - 1203-7 SB - M CY - FRANCE IP - 17 VI - 48 JC - ULD EM - 7212 PMID- 4341282 CU - 93 TT - Etude anatomo-clinique d'un cas de leptospirose grave. SO - Sem Hop 1972 Apr 8;48(17):1203-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [37 medline neighbors] UI - 72265282 AU - Hemmer C AU - Duval J AU - Lataste-Dorolle C TI - [Laboratory verifications of leptospirosis] LA - Fre MH - Adult MH - Agglutination Tests MH - Animal MH - Bacteriological Techniques MH - Complement Fixation Tests MH - English Abstract MH - Guinea Pigs MH - Hamsters MH - Human MH - Leptospira/isolation & purification/pathogenicity MH - Leptospira interrogans/*isolation & purification MH - Male MH - Methods MH - Middle Age MH - Rabbits MH - *Serodiagnosis MH - Weil's Disease/blood/cerebrospinal fluid/*diagnosis PT - JOURNAL ARTICLE DA - 721019 DP - 1972 Apr 8 IS - 0037-1777 TA - Sem Hop PG - 1193-201 SB - M CY - FRANCE IP - 17 VI - 48 JC - ULD EM - 7212 PMID- 4341281 CU - 93 TT - A propos des confirmations de laboratoire dans les leptospiroses. SO - Sem Hop 1972 Apr 8;48(17):1193-201 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 73030568 AU - Rogers RJ AU - Flanagan M AU - Hill MW TI - A survey of infectious causes of reproductive failure in beef cattle in north-eastern Australia. LA - Eng MH - Abortion, Veterinary/etiology MH - Animal MH - Australia MH - Bacterial Infections/*veterinary MH - Brucellosis, Bovine MH - Cattle MH - Cattle Diseases/*etiology MH - Endometritis/veterinary MH - Female MH - Genitalia, Female/microbiology MH - Infertility, Female/*veterinary MH - Leptospirosis/veterinary MH - Mycoplasma/isolation & purification MH - Mycoplasma Infections/veterinary MH - Ovarian Diseases/veterinary MH - Pregnancy MH - Pregnancy Complications/*veterinary MH - Trichomonas/isolation & purification MH - Trichomonas Infections/veterinary MH - Uterus/abnormalities MH - Vibrio/isolation & purification MH - Vibrio Infections/veterinary PT - JOURNAL ARTICLE DA - 730103 DP - 1972 Apr IS - 0005-0423 TA - Aust Vet J PG - 203-7 SB - M CY - AUSTRALIA IP - 4 VI - 48 JC - 9IE EM - 7302 PMID- 5082487 SO - Aust Vet J 1972 Apr;48(4):203-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 72253536 AU - Sueri LA AU - Ielasi G TI - [Sporadic leptospirosis in the Brescia district] LA - Ita MH - Agglutination Tests MH - Human MH - Italy MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*epidemiology MH - Seasons MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 720930 DP - 1972 Apr IS - 0017-0321 TA - G Mal Infett Parassit PG - 245-9 CY - ITALY IP - 4 VI - 24 JC - FD7 EM - 7212 PMID- 5050305 CU - 88 TT - Ulteriori osservazioni sulla leptospoirosi sporadica nella provincia di Brescia. SO - G Mal Infett Parassit 1972 Apr;24(4):245-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 72250834 AU - Saddy JC AU - Silva JJ da AU - Netto MB TI - [Anatomo-pathological study of the heart in leptospirosis] LA - Por MH - Adult MH - Autopsy MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*pathology MH - Male MH - Middle Age MH - Myocardium/*pathology PT - JOURNAL ARTICLE DA - 720929 DP - 1972 Apr IS - 0034-7264 TA - Rev Bras Med PG - 171-5 CY - BRAZIL IP - 4 VI - 29 JC - RJ5 EM - 7212 PMID- 5049282 TT - Estudo anatomopatologico do coracao naleptospirose. SO - Rev Bras Med 1972 Apr;29(4):171-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 73251006 AU - Mukherjea AK AU - Sen AK AU - Das AK AU - Mukherjee TP AU - Chatterjee BD AU - Mukherjee MK AU - Banik BG TI - An outbreak of leptospirosis in Howrah, West Bengal. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agglutination Tests MH - Child MH - Child, Preschool MH - Disease Outbreaks/*epidemiology MH - Female MH - Human MH - India MH - Infant MH - Leptospira interrogans MH - Leptospirosis/drug therapy/*epidemiology MH - Male MH - Middle Age MH - Tetracycline/therapeutic use PT - JOURNAL ARTICLE DA - 731112 DP - 1972 Apr IS - 0068-5372 TA - Bull Calcutta Sch Trop Med PG - 26-7 CY - INDIA IP - 2 VI - 20 JC - BDS EM - 7312 PMID- 4666675 CU - 88 SO - Bull Calcutta Sch Trop Med 1972 Apr;20(2):26-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 73093580 AU - Branson D TI - Timely topics in microbiology miscellaneous bacteria. LA - Eng MH - Actinomycetales MH - Bacteria/*classification/isolation & purification MH - *Bacterial Infections MH - *Bibliography MH - Chlamydia MH - Leptospira MH - Mycoplasma MH - Rickettsia MH - Treponema PT - BIBLIOGRAPHY PT - JOURNAL ARTICLE DA - 730403 DP - 1972 Apr IS - 0002-9335 TA - Am J Med Technol PG - 122-9 SB - M CY - UNITED STATES IP - 4 VI - 38 JC - 3LO EM - 7305 PMID- 4568439 CU - 90 SO - Am J Med Technol 1972 Apr;38(4):122-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [19 medline neighbors] UI - 72166292 AU - Alexander AD AU - Flyger V AU - Herman YF AU - McConnell SJ AU - Rothstein N AU - Yager RH TI - Survey of wild mammals in a Chesapeake Bay area for selected zoonoses. LA - Eng MH - Adenoviridae Infections/epidemiology/veterinary MH - Animal MH - Bacterial Infections/*veterinary MH - Carnivora MH - Helminthiasis/epidemiology/veterinary MH - Leptospirosis/epidemiology/veterinary MH - Listeria Infections/epidemiology/veterinary MH - Maryland MH - Opossums MH - Parasitic Diseases/*veterinary MH - Poxviridae Infections/epidemiology/veterinary MH - Raccoons MH - Rickettsia Infections/epidemiology/veterinary MH - Rodentia MH - Virus Diseases/*veterinary MH - *Zoonoses PT - JOURNAL ARTICLE DA - 720628 DP - 1972 Apr IS - 0090-3558 TA - J Wildl Dis PG - 119-26 SB - M CY - UNITED STATES IP - 2 VI - 8 JC - KEM EM - 7208 PMID- 4336527 CU - 93 SO - J Wildl Dis 1972 Apr;8(2):119-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [6 medline neighbors] UI - 72158372 AU - Baldwin EW AU - White FH AU - Edds GT TI - Efficacy of certain chemical agents in the treatment of leptospiruria in hamsters. LA - Eng MH - Amides/therapeutic use MH - Animal MH - Azaguanine/pharmacology/therapeutic use MH - Azoles/therapeutic use MH - Colistin/pharmacology/therapeutic use MH - Cycloserine/pharmacology/therapeutic use MH - Dihydrostreptomycin Sulfate/pharmacology/therapeutic use MH - *Hamsters MH - Leptospira canicola/drug effects MH - Leptospirosis/drug therapy/*veterinary MH - Polyamines/therapeutic use MH - Propylamines/therapeutic use MH - Rodent Diseases/*drug therapy MH - Selenium/therapeutic use MH - Thiouracil/pharmacology/therapeutic use MH - 6-Mercaptopurine/pharmacology/therapeutic use PT - JOURNAL ARTICLE DA - 720620 DP - 1972 Apr IS - 0002-9645 TA - Am J Vet Res PG - 863-5 SB - M CY - UNITED STATES IP - 4 VI - 33 JC - 40C EM - 7208 PMID- 4111742 CU - 95 SO - Am J Vet Res 1972 Apr;33(4):863-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72200552 AU - Chan YF TI - Hyperosmolar non-ketotic diabetic coma following leptospirosis--a case report. LA - Eng MH - Aged MH - Diabetic Coma/drug therapy/*etiology MH - Human MH - Insulin/therapeutic use MH - Leptospirosis/*complications MH - Male MH - Osmolar Concentration MH - *Water-Electrolyte Balance PT - JOURNAL ARTICLE DA - 720807 DP - 1972 Mar IS - 0025-7303 TA - Med J Malaya PG - 211-4 CY - MALAYSIA IP - 3 VI - 26 JC - BDM EM - 7210 RO - M:CNR PMID- 5031019 LR - 920406 SO - Med J Malaya 1972 Mar;26(3):211-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 72160028 AU - Prodrom I TI - [Considerations on hemorrhagic diathesis in leptospirosis and on the pathogenesis of grave forms] LA - Rum MH - Adolescence MH - Adult MH - English Abstract MH - Hemorrhagic Diathesis/*etiology MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Septicemia/etiology MH - Shock, Hemorrhagic/etiology MH - Shock, Septic/etiology MH - Weil's Disease/complications PT - JOURNAL ARTICLE DA - 720621 DP - 1972 Mar-Apr IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 97-110 CY - ROMANIA IP - 2 VI - 17 JC - MXQ EM - 7208 PMID- 5018437 TT - Consideratii asupra diatezei hemoragice din leptospiroza si a patogeniei formelor grave. SO - Microbiol Parazitol Epidemiol (Bucur) 1972 Mar-Apr;17(2):97-110 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 72131217 AU - Kracmarova A AU - Vesely L TI - [Leptospirosis in the etiology of local uveitides] LA - Cze MH - Agglutination Tests MH - Czechoslovakia MH - Disease Outbreaks MH - English Abstract MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*complications MH - Uveitis/diagnosis/*etiology PT - JOURNAL ARTICLE DA - 720516 DP - 1972 Mar IS - 0009-059X TA - Cesk Oftalmol PG - 112-6 CY - CZECHOSLOVAKIA IP - 2 VI - 28 JC - CVD EM - 7207 PMID- 5011455 TT - Leptospiroza v etiologii nasich uveitid. SO - Cesk Oftalmol 1972 Mar;28(2):112-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 73144331 AU - Nicolescu M AU - Moldovan G TI - Leptospira complement fixation test with Patoc antigen in pigs accidentally infected with the pomona serotype. LA - Eng MH - Animal MH - Antibodies/analysis MH - Antigens MH - *Complement Fixation Tests MH - Leptospirosis/diagnosis/*veterinary MH - Rabbits MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 730518 DP - 1972 Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 69-73 CY - ROMANIA IP - 1 VI - 31 JC - 8EM EM - 7307 PMID- 4676373 CU - 85 SO - Arch Roum Pathol Exp Microbiol 1972 Mar;31(1):69-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73144325 AU - Topciu V AU - Spinu I AU - Trinh-Thi-Hang-Quy TI - [On certain cases of leptospirosis with paradoxical serological reactions] LA - Fre MH - Antibodies/*analysis MH - English Abstract MH - Human MH - Leptospira/classification MH - Leptospirosis/*diagnosis MH - *Serodiagnosis MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 730518 DP - 1972 Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 21-9 CY - ROMANIA IP - 1 VI - 31 JC - 8EM EM - 7307 PMID- 4656782 TT - Considerations sur certains cas de leptospirose a reactions serologiques paradoxales. SO - Arch Roum Pathol Exp Microbiol 1972 Mar;31(1):21-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 73000636 AU - Yanagawa R AU - Takashima I TI - Leptospira serotype kremastos of bovine origin. LA - Eng MH - Animal MH - Antibodies/analysis MH - Cattle MH - Immunodiffusion MH - Leptospira/immunology/*isolation & purification MH - *Serotyping PT - JOURNAL ARTICLE DA - 721108 DP - 1972 Mar IS - 0021-5139 TA - Jpn J Microbiol PG - 147-8 SB - M CY - JAPAN IP - 2 VI - 16 JC - KMF EM - 7301 PMID- 4626996 CU - 91 SO - Jpn J Microbiol 1972 Mar;16(2):147-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 72153304 AU - MacCallum FO TI - 1971 International Symposium on Viral Hepatitis. Historical perspectives. LA - Eng MH - Diagnosis, Differential MH - Europe MH - Hepatitis A/*history/immunology MH - Hepatitis B/diagnosis/history/immunology MH - History of Medicine, 19th Cent. MH - History of Medicine, 20th Cent. MH - Human MH - Jaundice/etiology/history MH - Leptospirosis/diagnosis MH - United States MH - Vaccination/adverse effects/history MH - Yellow Fever/history PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 720613 DP - 1972 Feb 26 IS - 0008-4409 TA - Can Med Assoc J PG - Suppl:423-6 SB - A SB - M CY - CANADA VI - 106 JC - CKW EM - 7208 PMID- 4552628 CU - 90 SO - Can Med Assoc J 1972 Feb 26;106:Suppl:423-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 72195450 AU - Morter RL TI - Comments on control of leptospiral infections. LA - Eng MH - Agglutination Tests MH - Animal MH - Animal Diseases/*immunology MH - Antibodies/analysis MH - Antibody Specificity MH - Antigens/analysis MH - Bacterial Vaccines/administration & dosage MH - IgG/analysis MH - IgM/analysis MH - Immune Sera/analysis MH - Kidney Diseases/prevention & control/veterinary MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/immunology/prevention & control/*veterinary MH - Neutralization Tests MH - Serotyping MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 720803 DP - 1972 Feb 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 637-9 SB - M CY - UNITED STATES IP - 4 VI - 160 JC - HAV EM - 7209 PMID- 5063984 CU - 85 SO - J Am Vet Med Assoc 1972 Feb 15;160(4):637-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 72195448 AU - Hanson LE TI - Problems related to epizootiology of swine leptospirosis. LA - Eng MH - Animal MH - Carrier State/prevention & control/veterinary MH - Diagnosis, Differential MH - Disease Outbreaks/diagnosis/*veterinary MH - Feces/microbiology MH - Illinois MH - Kidney/microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/epidemiology/prevention & control/urine/veterinary MH - Liver/microbiology MH - Rodent Control MH - Serodiagnosis MH - Serotyping MH - Swine MH - Swine Diseases/diagnosis/epidemiology/microbiology/*prevention & control/urine MH - Urine/microbiology MH - Vaccination MH - Water Microbiology PT - JOURNAL ARTICLE PT - REVIEW DA - 720803 DP - 1972 Feb 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 631-4 SB - M CY - UNITED STATES IP - 4 VI - 160 JC - HAV EM - 7209 RF - 29 PMID- 4555396 CU - 90 SO - J Am Vet Med Assoc 1972 Feb 15;160(4):631-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [42 medline neighbors] UI - 72195443 AU - Kaeberle ML TI - Do mixed bacterins and autogenous bacterins have merit? LA - Eng MH - Animal MH - Antibody Formation MH - Antigens MH - Bacteria/growth & development MH - *Bacterial Vaccines/biosynthesis MH - Blood Bactericidal Activity MH - Cells, Cultured/microbiology MH - *Drug Synergism MH - Epithelium/immunology MH - Erysipelothrix Infections/immunology MH - Escherichia coli/immunology MH - Escherichia coli Infections/immunology/veterinary MH - Evaluation Studies MH - IgA/biosynthesis MH - IgM/biosynthesis MH - Leptospirosis/immunology/veterinary MH - Lymphatic System/immunology MH - Phagocytosis MH - Salmonella Infections, Animal/immunology MH - Serotyping MH - Swine MH - Swine Diseases/immunology PT - JOURNAL ARTICLE DA - 720803 DP - 1972 Feb 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 609-11 SB - M CY - UNITED STATES IP - 4 VI - 160 JC - HAV EM - 7209 PMID- 4555395 CU - 90 SO - J Am Vet Med Assoc 1972 Feb 15;160(4):609-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [18 medline neighbors] UI - 72195462 AU - Stockton JJ TI - Summary of the colloquium on immunity to selected diseases of swine. LA - Eng MH - African Swine Fever/immunology MH - Animal MH - Bacterial Vaccines/therapeutic use MH - Drug Therapy MH - Enterovirus/classification MH - Enterovirus Infections/immunology/veterinary MH - Food Supply MH - Hog Cholera/immunology MH - Leptospirosis/immunology/prevention & control MH - Parasitic Diseases/immunology/veterinary MH - Swine MH - Swine Diseases/*immunology MH - Tuberculosis/immunology/veterinary MH - Zoonoses PT - JOURNAL ARTICLE DA - 720803 DP - 1972 Feb 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 667-8 SB - M CY - UNITED STATES IP - 4 VI - 160 JC - HAV EM - 7209 PMID- 4337847 CU - 93 SO - J Am Vet Med Assoc 1972 Feb 15;160(4):667-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 72195449 AU - Huhn RG TI - Current status of leptospiral immunizing agents for use in swine. LA - Eng MH - Animal MH - Bacterial Vaccines/*standards MH - Carrier State/prevention & control/veterinary MH - Diagnosis, Differential MH - Diagnostic Errors MH - Dihydrostreptomycin Sulfate/*administration & dosage MH - Leptospira/classification/*immunology MH - Leptospirosis/diagnosis/*immunology MH - Rodent Control MH - Swine MH - Swine Diseases/diagnosis/*immunology MH - Vaccination PT - JOURNAL ARTICLE DA - 720803 DP - 1972 Feb 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 634-7 SB - M CY - UNITED STATES IP - 4 VI - 160 JC - HAV EM - 7209 PMID- 4113120 CU - 95 SO - J Am Vet Med Assoc 1972 Feb 15;160(4):634-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 72141434 AU - Tesarova-Magrova J AU - Sramkova L TI - [Cardiovascular disorders in leptospirosis] LA - Ger MH - Adolescence MH - Adult MH - Arrhythmia, Sinus/etiology MH - Child MH - Electrocardiography MH - English Abstract MH - Heart Auscultation MH - Heart Diseases/diagnosis/*etiology MH - Human MH - Leptospirosis/*complications MH - Male MH - Myocardial Diseases/etiology MH - Myocarditis/drug therapy/etiology MH - Pericarditis/etiology MH - Time Factors PT - JOURNAL ARTICLE DA - 720601 DP - 1972 Feb 4 IS - 0025-8458 TA - Med Klin PG - 156-9 SB - M CY - GERMANY, WEST IP - 5 VI - 67 JC - M4E EM - 7207 PMID- 5014140 CU - 90 TT - Kardiovaskulare Storungen bei Leptospirose. SO - Med Klin 1972 Feb 4;67(5):156-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72151529 AU - Udomsakdi S AU - Potha U TI - The diagnosis of leptospirosis by fluorescent antibody technique using saprophytic Leptospira as a genus-specific antigen. LA - Eng MH - *Antigens MH - Antigens, Bacterial MH - *Fluorescent Antibody Technique MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Species Specificity PT - JOURNAL ARTICLE DA - 720608 DP - 1972 Feb IS - 0025-7036 TA - J Med Assoc Thai PG - 101-6 CY - THAILAND IP - 2 VI - 55 JC - IZR EM - 7208 PMID- 4552546 CU - 90 SO - J Med Assoc Thai 1972 Feb;55(2):101-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72104765 AU - Cox CD TI - Shape of Treponema pallidum. LA - Eng MH - Bacteriological Techniques MH - Leptospira/cytology MH - Microscopy, Phase-Contrast MH - Spirochaeta/cytology MH - Treponema/cytology MH - Treponema pallidum/*cytology PT - JOURNAL ARTICLE DA - 720418 DP - 1972 Feb IS - 0021-9193 TA - J Bacteriol PG - 943-4 SB - M CY - UNITED STATES IP - 2 VI - 109 JC - HH3 EM - 7206 PMID- 4550825 CU - 90 SO - J Bacteriol 1972 Feb;109(2):943-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 72113108 AU - Northway RB TI - Leptospirosis in a California sea lion. LA - Eng MH - Animal MH - California MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - *Pinnipedia PT - JOURNAL ARTICLE DA - 720428 DP - 1972 Feb IS - 0042-4889 TA - Vet Med Small Anim Clin PG - 138 passim CY - UNITED STATES IP - 2 VI - 67 JC - XBO EM - 7206 PMID- 4481104 CU - 88 SO - Vet Med Small Anim Clin 1972 Feb;67(2):138 passim ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73004465 AU - Miller NG TI - Observations of the carrier state in hamsters infected with Leptospira interrogans serotype Pomona. LA - Eng MH - Animal MH - Bacteriuria MH - Carrier State/*microbiology MH - *Hamsters MH - Kidney Tubules/microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/*microbiology MH - Serotyping MH - Species Specificity MH - Variation (Genetics) PT - JOURNAL ARTICLE DA - 721115 DP - 1972 IS - 0300-8584 TA - Med Microbiol Immunol (Berl) PG - 1-8 SB - M CY - GERMANY, WEST IP - 1 VI - 158 JC - M58 EM - 7301 PMID- 5070918 SO - Med Microbiol Immunol (Berl) 1972;158(1):1-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 72138136 AU - Straton A AU - Straton C AU - Bercovici C TI - [Experimental leptospirosis in small wild rodents] LA - Fre MH - Animal MH - Antibodies/analysis MH - Antigens/administration & dosage MH - Antigens, Bacterial MH - Carrier State MH - English Abstract MH - Hemagglutination Tests MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/*immunology MH - *Rodent Diseases MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 720528 DP - 1972 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 115-21 SB - M CY - CZECHOSLOVAKIA IP - 1 VI - 16 JC - IEV EM - 7207 PMID- 5062512 CU - 85 TT - Leptospirose experimentale chez les petits rongeurs sauvages. SO - J Hyg Epidemiol Microbiol Immunol 1972;16(1):115-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72101577 AU - Hubbert WT TI - Bacteria and spermatozoa in the canine urinary bladder. LA - Eng MH - Age Factors MH - Animal MH - Bacteria/*isolation & purification MH - Bacteriuria/*veterinary MH - Bladder/*microbiology MH - Breeding MH - Dog Diseases/microbiology MH - *Dogs MH - Female MH - Leptospira/isolation & purification MH - Male MH - Sex Factors MH - *Spermatozoa MH - Urine/microbiology MH - Vesico-Ureteral Reflux/veterinary PT - JOURNAL ARTICLE DA - 720412 DP - 1972 Jan IS - 0010-8901 TA - Cornell Vet PG - 13-20 SB - M CY - UNITED STATES IP - 1 VI - 62 JC - DRI EM - 7206 PMID- 5061940 CU - 85 SO - Cornell Vet 1972 Jan;62(1):13-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72240304 AU - Barsoum IS AU - Moch RW AU - Botros BA TI - Leptospiral agglutinating antibodies in sera of patients with hepatitis in Cairo hospitals (Egypt). LA - Eng MH - Agglutination Tests MH - Antibodies/*analysis MH - Egypt MH - Hepatitis/*immunology MH - Human MH - Leptospira/*immunology MH - Leptospirosis/diagnosis PT - JOURNAL ARTICLE DA - 720921 DP - 1972 IS - 0013-2446 TA - J Egypt Public Health Assoc PG - 114-20 CY - EGYPT IP - 2 VI - 47 JC - I07 EM - 7211 PMID- 5046579 SO - J Egypt Public Health Assoc 1972;47(2):114-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 72085218 AU - Paul JR AU - Hanson LE AU - Schnurrenberger PR AU - Martin RJ TI - Leptospira interrogans serotypes ballum and grippotyphosa isolated from the muskrat. LA - Eng MH - Agglutination Tests MH - Animal MH - Female MH - Leptospira/*isolation & purification MH - Leptospirosis/immunology/microbiology/veterinary MH - Male MH - Rodent Diseases/immunology/microbiology MH - *Rodentia MH - Serotyping PT - JOURNAL ARTICLE DA - 720322 DP - 1972 Jan IS - 0090-3558 TA - J Wildl Dis PG - 54-6 SB - M CY - UNITED STATES IP - 1 VI - 8 JC - KEM EM - 7205 PMID- 5007902 SO - J Wildl Dis 1972 Jan;8(1):54-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 74269907 AU - Munnich D AU - Lakatos M TI - Treatment of leptospirosis with Semicillin. LA - Eng MH - Administration, Oral MH - Ampicillin/administration & dosage/*therapeutic use MH - Female MH - Human MH - Leptospirosis/*drug therapy MH - Male MH - Serotyping PT - JOURNAL ARTICLE DA - 740911 DP - 1972 IS - 0040-5949 TA - Ther Hung PG - 152-5 CY - HUNGARY IP - 4 VI - 20 JC - VP3 EM - 7411 RO - O:45 RO - C:10 PMID- 4679501 CU - 86 SO - Ther Hung 1972;20(4):152-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 73015684 AU - Mailloux M AU - Richard C TI - [Research on lysine and ornithine decarboxylases and arginine dihydrolase in leptospira] LA - Fre MH - Arginine MH - Carboxy-Lyases/*metabolism MH - Culture Media MH - English Abstract MH - Fermentation MH - Glucose/metabolism MH - Hydrolases/*metabolism MH - Leptospira/*enzymology/immunology/metabolism MH - Leptospira canicola/enzymology/metabolism MH - Leptospira interrogans/enzymology MH - Lysine MH - Ornithine MH - Serotyping PT - JOURNAL ARTICLE DA - 721204 DP - 1972 Jan-Feb IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 50-5 SB - M CY - FRANCE IP - 1 VI - 65 JC - C4G EM - 7301 PMID- 4677873 CU - 86 TT - Recherche des lysines et ornithine-decarboxylases et de l'arginine- dihydrolase chez les leptospires. SO - Bull Soc Pathol Exot Filiales 1972 Jan-Feb;65(1):50-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 73025271 AU - Chorvath B AU - Bakoss P TI - Studies on leptospiral lipase. II. Lipase activity of virulent and avirulent leptospirae. LA - Eng MH - Animal MH - Blood/microbiology MH - Fatty Acids, Nonesterified/analysis MH - Human MH - Kidney/microbiology MH - Leptospira/*enzymology/isolation & purification MH - Leptospirosis/enzymology MH - Lipase/*metabolism MH - Photometry MH - Rats MH - Virulence PT - JOURNAL ARTICLE DA - 730102 DP - 1972 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 352-7 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 16 JC - IEV EM - 7302 PMID- 4673076 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1972;16(3):352-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73025270 AU - Sveshnikova NP AU - Chernukha YG TI - To the question of the character of variability of the antigenic structure of leptospira. LA - Eng MH - Animal MH - Antigens/*analysis MH - Disease Reservoirs MH - Genetics, Microbial MH - Human MH - Leptospira/*classification/immunology MH - Leptospirosis/genetics MH - Mammals MH - Mutation MH - Serotyping MH - Variation (Genetics) PT - JOURNAL ARTICLE DA - 730102 DP - 1972 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 346-51 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 16 JC - IEV EM - 7302 PMID- 4673075 CU - 88 SO - J Hyg Epidemiol Microbiol Immunol 1972;16(3):346-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 73025265 AU - Sebek Z AU - Sery V AU - Saboor A TI - Results of the first leptospirological study carried out in Afghanistan. LA - Eng MH - Afghanistan MH - Animal MH - Animals, Domestic MH - Antibodies/analysis MH - Disease Reservoirs MH - Disease Vectors MH - Leptospirosis/*epidemiology/immunology MH - Rural Population MH - Serodiagnosis MH - Urban Population PT - JOURNAL ARTICLE DA - 730102 DP - 1972 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 314-24 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 16 JC - IEV EM - 7302 PMID- 4673073 CU - 88 SO - J Hyg Epidemiol Microbiol Immunol 1972;16(3):314-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 73025264 AU - Bercovici C AU - Straton C AU - Straton A AU - Radulescu P AU - Brebenel G TI - [The natural leptospira reservoirs in the lower basin of the river Pruth] LA - Ger MH - Animal MH - Antibodies/analysis MH - Cattle MH - Cattle Diseases/epidemiology MH - Child MH - *Disease Reservoirs MH - Disease Vectors MH - English Abstract MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology/immunology MH - Mice MH - Rodentia MH - Romania MH - Serotyping MH - Ukraine PT - JOURNAL ARTICLE DA - 730102 DP - 1972 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 303-13 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 16 JC - IEV EM - 7302 PMID- 4673072 CU - 88 TT - Studium der naturrlichen Leptospirenreservoire im unteren Becken des Flusses Pruth. SO - J Hyg Epidemiol Microbiol Immunol 1972;16(3):303-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 74254276 AU - Sebek Z AU - Heneberg D AU - Heneberg N TI - Natural and anthropurgic foci of leptospirosis in the Socialist Republic of Macedonia. LA - Eng MH - Agglutination Tests MH - Animal MH - Carnivora MH - Cat Diseases/epidemiology MH - Cats MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Reservoirs/*veterinary MH - Goats MH - Hedgehogs MH - Horse Diseases/epidemiology MH - Horses MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Perissodactyla MH - Rodent Diseases/epidemiology MH - Rodentia MH - Sheep MH - Sheep Diseases/epidemiology MH - Turtles MH - Yugoslavia PT - JOURNAL ARTICLE DA - 740903 DP - 1972 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 53-60 CY - CZECHOSLOVAKIA IP - 1 VI - 19 JC - F2T EM - 7410 RO - O:45 RO - C:29 PMID- 4670808 CU - 88 SO - Folia Parasitol (Praha) 1972;19(1):53-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 74150093 AU - Oravec C AU - Cambelova J AU - Kmety E TI - Experimental biotherapy by leptospiral infection. VII. Quantitative titration of the tumoricidal effect of leptospirae by means of 51Cr labelled target cells of mouse ascites tumours. LA - Eng MH - Animal MH - Biological Products/*therapeutic use MH - Carcinoma, Ehrlich Tumor/immunology/pathology/*therapy MH - Cell Line MH - *Chromium Radioisotopes MH - Cytotoxicity Tests, Immunologic MH - Densitometry MH - *Leptospira/immunology MH - Mice PT - JOURNAL ARTICLE DA - 740625 DP - 1972 IS - 0028-2685 TA - Neoplasma PG - 639-52 SB - M CY - CZECHOSLOVAKIA IP - 6 VI - 19 JC - NVO EM - 7408 PMID- 4670380 SO - Neoplasma 1972;19(6):639-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73090282 AU - Varela G AU - Avendano E AU - Velasco R AU - Zarate Aquino MI TI - [Serology of leptospirosis in the Mexican Republic] LA - Spa MH - Animal MH - Cats MH - Dogs MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Methods MH - Mexico MH - Rabbits MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 730329 DP - 1972 Jan-Mar IS - 0034-8384 TA - Rev Invest Salud Publica PG - 53-7 CY - MEXICO IP - 1 VI - 32 JC - SCY EM - 7305 PMID- 4650276 CU - 90 TT - Serologia de la leptospirosis en la Republica Mexicana. SO - Rev Invest Salud Publica 1972 Jan-Mar;32(1):53-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73141370 AU - Shinagawa M AU - Yanagawa R TI - Isolation and characterization of a leptospiral type-specific antigen. LA - Eng MH - Amino Acids/analysis MH - Amino Sugars/analysis MH - Animal MH - Antibody Specificity MH - Antigens, Bacterial/analysis/*isolation & purification MH - Chemistry MH - Chromatography, Paper MH - Complement Fixation Tests MH - Immunodiffusion MH - Leptospira/*immunology MH - Microscopy, Electron MH - Rabbits/immunology MH - Sodium Dodecyl Sulfate MH - Spectrophotometry, Infrared MH - Spectrophotometry, Ultraviolet MH - Viscosity PT - JOURNAL ARTICLE DA - 730510 DP - 1972 Jan IS - 0019-9567 TA - Infect Immun PG - 12-9 SB - M CY - UNITED STATES IP - 1 VI - 5 JC - GO7 EM - 7307 PMID- 4632464 CU - 91 SO - Infect Immun 1972 Jan;5(1):12-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 73124584 AU - Ivanov I TI - Mus musculus and Microtus arvalis in the rice-fields areas as carriers of leptospirae. LA - Eng MH - Animal MH - Bulgaria MH - *Disease Reservoirs MH - Leptospira MH - *Leptospirosis MH - *Mice MH - Rice PT - JOURNAL ARTICLE DA - 730419 DP - 1972 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 219-22 CY - BULGARIA IP - 3 VI - 14 JC - F19 EM - 7306 PMID- 4631702 CU - 91 SO - Folia Med (Plovdiv) 1972;14(3):219-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 73131281 AU - Teichmann W TI - [Hepatitides in infectious diseases] LA - Ger MH - Arbovirus Infections/complications MH - Bacterial Infections/complications MH - Brucellosis/complications MH - Enterobacteriaceae Infections/complications MH - Europe MH - Hepatitis A/epidemiology/*etiology/microbiology MH - Human MH - Infant, Newborn MH - Infectious Mononucleosis/complications MH - Leptospirosis/complications MH - Mycoses/complications MH - Protozoan Infections/complications MH - Sarcoidosis/complications MH - Schistosomiasis/complications MH - Tuberculosis/complications MH - Tuberculosis, Hepatic/etiology PT - JOURNAL ARTICLE PT - REVIEW DA - 730502 DP - 1972 IS - 0012-1053 TA - Dtsch Z Verdau Stoffwechselkr PG - 55-8 SB - M CY - GERMANY, EAST IP - 1 VI - 32 JC - ED2 EM - 7306 RF - 30 PMID- 4570110 CU - 90 TT - Hepatitiden bei Infektionskrankheiten. SO - Dtsch Z Verdau Stoffwechselkr 1972;32(1):55-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73034436 AU - Abdussalam M AU - Alexander AD AU - Babudieri B AU - Bogel K AU - Borg-Petersen C AU - Faine S AU - Kmety E AU - Lataste-Dorolle C AU - Turner LH TI - Research needs in leptospirosis. LA - Eng MH - Agglutination MH - Agglutination Tests MH - Animal MH - Antigens, Bacterial MH - Complement Fixation Tests MH - Disease Reservoirs MH - DNA, Bacterial MH - Fluorescent Antibody Technique MH - Genetics, Microbial MH - Human MH - Immunity MH - Leptospira/classification/cytology/immunology/isolation & purification/metabolism MH - *Leptospirosis/diagnosis/epidemiology/microbiology/prevention & control/veterinary MH - Serotyping MH - Vaccination PT - JOURNAL ARTICLE PT - REVIEW DA - 730109 DP - 1972 IS - 0042-9686 TA - Bull World Health Organ PG - 113-22 CY - SWITZERLAND IP - 1 VI - 47 JC - C80 EM - 7302 RF - 42 PMID- 4563541 CU - 90 SO - Bull World Health Organ 1972;47(1):113-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 73000168 AU - Durner K AU - Guttner H AU - Kamieth R AU - Rothe F AU - Schmidt P AU - Winkler H AU - Kludas KH TI - [Supplementary components as factors in culture media for bacteria and cell cultures] LA - Ger MH - Animal MH - Bacteria/*growth & development MH - Bacteriological Techniques MH - Chick Embryo MH - Culture Media/*standards MH - English Abstract MH - Erysipelothrix/growth & development MH - Fibroblasts MH - Hela Cells MH - Kidney MH - Leptospira/growth & development MH - Mycoplasma/growth & development MH - Pasteurella/growth & development MH - Peptones/standards MH - Swine MH - Thyroid Gland MH - *Tissue Culture MH - Trypsin PT - JOURNAL ARTICLE DA - 721108 DP - 1972 IS - 0003-9055 TA - Arch Exp Veterinarmed PG - 25-31 SB - M CY - GERMANY, EAST IP - 1 VI - 26 JC - 70I EM - 7301 PMID- 4560560 CU - 90 TT - Supplemente als Bestandteil von Nahrmedien fur Bakterien- und Zellkulturen. SO - Arch Exp Veterinarmed 1972;26(1):25-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [29 medline neighbors] UI - 72226633 AU - Frenkel JK TI - Infection and immunity in hamsters. LA - Eng MH - Adrenal Gland Hyperfunction/immunology MH - Amyloidosis MH - Animal MH - Antibiotics/toxicity MH - Central Nervous System/immunology MH - Cholangitis/veterinary MH - Ectoparasitic Infestations MH - Endotoxins/toxicity MH - Enteritis MH - Glucocorticoids MH - *Hamsters MH - Helminthiasis MH - Hypersensitivity, Delayed MH - *Immunity MH - Immunity, Cellular MH - Infection/*pathology MH - Leptospirosis/pathology MH - Lymphoid Tissue/transplantation MH - Mycoplasma Infections/pathology MH - Mycoses MH - Protozoan Infections MH - Radiation Injuries, Experimental/complications MH - Rickettsia Infections/pathology MH - Sarcoidosis/pathology MH - Sulfadiazine/therapeutic use MH - Virus Diseases/pathology PT - JOURNAL ARTICLE PT - REVIEW DA - 720905 DP - 1972 IS - 0079-6263 TA - Prog Exp Tumor Res PG - 326-67 CY - SWITZERLAND VI - 16 JC - Q0V EM - 7211 RF - 158 PMID- 4557238 CU - 90 SO - Prog Exp Tumor Res 1972;16:326-67 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 72105341 AU - Cook JE AU - Coles EH AU - Garner FM TI - Detecting leptospires in formalin-fixed hamster tissues by fluorescent antibody techniques. LA - Eng MH - Animal MH - Antigens, Bacterial MH - *Fluorescent Antibody Technique MH - Hamsters MH - Leptospira/immunology/*isolation & purification MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/microbiology/veterinary MH - Methods PT - JOURNAL ARTICLE DA - 720418 DP - 1972 Jan IS - 0002-9645 TA - Am J Vet Res PG - 277-82 SB - M CY - UNITED STATES IP - 1 VI - 33 JC - 40C EM - 7206 PMID- 4550843 CU - 90 SO - Am J Vet Res 1972 Jan;33(1):277-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 72084127 AU - Hirschberg N AU - Bell M TI - Fluorescent antibody reactions to leptospira with fractions of immune serum. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Chromatography, Gel MH - *Fluorescent Antibody Technique MH - Immune Sera MH - Leptospirosis/*diagnosis/immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 720320 DP - 1972 Jan IS - 0017-9035 TA - Health Lab Sci PG - 39-45 SB - M CY - UNITED STATES IP - 1 VI - 9 JC - G2C EM - 7205 PMID- 4550259 CU - 90 SO - Health Lab Sci 1972 Jan;9(1):39-45 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73165477 TI - [Requirements in research on leptospirosis] LA - Fre MH - Animal MH - Antigens, Bacterial MH - Genetics, Microbial MH - Human MH - Leptospira/immunology/metabolism/pathogenicity MH - *Leptospirosis/therapy MH - *Research PT - JOURNAL ARTICLE DA - 730622 DP - 1972 IS - 0042-9686 TA - Bull World Health Organ PG - 641-50 CY - SWITZERLAND IP - 5 VI - 47 JC - C80 EM - 7308 PMID- 4540684 CU - 89 NI - A TT - Bosoins en matiere de recherches sur la leptospirose. SO - Bull World Health Organ 1972;47(5):641-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [13 medline neighbors] UI - 72075416 AU - Tong MJ AU - Youel DB AU - Cotten CL TI - Acute pneumonia in tropical infections. LA - Eng MH - Adolescence MH - Adult MH - Blood/microbiology MH - Female MH - Human MH - Leptospirosis/complications MH - Malaria/complications MH - Male MH - Military Personnel MH - Mycoplasma/isolation & purification MH - Plague/complications MH - Pneumonia/*etiology MH - Pneumonia, Staphylococcal/*etiology MH - Pneumonia, Viral/*etiology MH - Salmonella typhi/isolation & purification MH - Scrub Typhus/complications MH - Sputum/microbiology MH - Streptococcus pneumoniae/isolation & purification MH - Typhoid/complications MH - Yersinia pestis/isolation & purification PT - JOURNAL ARTICLE DA - 720308 DP - 1972 Jan IS - 0002-9637 TA - Am J Trop Med Hyg PG - 50-7 SB - A SB - M CY - UNITED STATES IP - 2 VI - 21 JC - 3ZQ EM - 7204 RO - M:MYA PMID- 4399843 LR - 830218 CU - 94 SO - Am J Trop Med Hyg 1972 Jan;21(2):50-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73242163 AU - Kadlcik K AU - Kramar R TI - [Specificity of the direct immunofluorescence reaction in leptospira] LA - Cze MH - Animal MH - Antigens MH - English Abstract MH - *Fluorescent Antibody Technique MH - Immune Sera MH - Leptospira/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 731028 DP - 1972 IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 301-6 CY - CZECHOSLOVAKIA IP - 6 VI - 21 JC - CSH EM - 7312 PMID- 4269462 CU - 92 TT - Specifita prime imunofluorescencni reakce u leptospir. SO - Cesk Epidemiol Mikrobiol Imunol 1972;21(6):301-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73242156 AU - Sebek Z AU - Chmela J TI - [Natural foci and reservoirs of leptospiroses in the Olomouc district] LA - Cze MH - Animal MH - Czechoslovakia MH - *Disease Reservoirs MH - Disease Vectors MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Rats PT - JOURNAL ARTICLE DA - 731028 DP - 1972 IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 159-64 CY - CZECHOSLOVAKIA IP - 3 VI - 21 JC - CSH EM - 7312 PMID- 4269457 CU - 92 TT - Prirodni ohniska a rezervoary leptospiroz na olomoucku. SO - Cesk Epidemiol Mikrobiol Imunol 1972;21(3):159-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 73242152 AU - Sebek Z AU - Wurst Z TI - [Leptospirosis of dogs in Czechoslovakia and its importance in the epidemiology of human leptospirosis] LA - Cze MH - Animal MH - Antibody Formation MH - Czechoslovakia MH - Disease Vectors MH - Dog Diseases/*immunology MH - Dogs MH - English Abstract MH - Human MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 731028 DP - 1972 IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 127-34 CY - CZECHOSLOVAKIA IP - 3 VI - 21 JC - CSH EM - 7312 PMID- 4269453 CU - 92 TT - Leptospiroza psu v Ceske socialisticke republice a jeji vyznam v epidemiologii lidske leptospirozy. SO - Cesk Epidemiol Mikrobiol Imunol 1972;21(3):127-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 72116629 AU - Sandhu TS AU - White FH TI - Evaluation of a macroscopic plate test and an indirect immunofluorescence test to detect leptospiral antibodies in bovine serum. LA - Eng MH - Agglutination Tests/*veterinary MH - Animal MH - Antibodies/*analysis MH - Cattle/*immunology MH - Cattle Diseases/immunology MH - Comparative Study MH - Evaluation Studies MH - False Positive Reactions MH - Fluorescent Antibody Technique/*veterinary MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospirosis/immunology/veterinary MH - Methods PT - JOURNAL ARTICLE DA - 720502 DP - 1972 Jan IS - 0008-4050 TA - Can J Comp Med Vet Sci PG - 34-7 SB - M CY - CANADA IP - 1 VI - 36 JC - CI0 EM - 7206 PMID- 4258543 CU - 92 SO - Can J Comp Med Vet Sci 1972 Jan;36(1):34-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 74280592 AU - Jiran E AU - Kadlec V AU - Svatos L TI - [Lyophilized trivalent vaccine against canine leptospirosis] LA - Cze MH - Animal MH - Antibody Formation MH - Distemper/immunology MH - Dog Diseases/immunology/*therapy MH - Dogs MH - English Abstract MH - *Freeze Drying MH - Hepatitis, Infectious Canine/immunology MH - *Immunotherapy MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 741011 DP - 1972 IS - 0375-8427 TA - Vet Med (Praha) PG - 367-77 SB - M CY - CZECHOSLOVAKIA IP - 6 VI - 17 JC - XBP EM - 7411 RO - O:46 RO - C:22 PMID- 4210739 CU - 91 TT - Lyofilizovana trivalentni vakcina proti leptospiroze psu EA - A SO - Vet Med (Praha) 1972;17(6):367-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 72161454 AU - Hermans PE AU - Goldstein NP AU - Wellman WE TI - Mollaret's meningitis and differential diagnosis of recurrent meningitis. Report of case, with review of the literature. LA - Eng MH - Abnormalities/complications MH - Anemia, Sickle Cell/complications MH - Brain Neoplasms/complications MH - Brucellosis/complications MH - Diagnosis, Differential MH - Echinococcosis MH - Fever/complications MH - Gamma-Globulins/cerebrospinal fluid MH - Glucose/cerebrospinal fluid MH - Headache/*complications MH - Human MH - Immunologic Deficiency Syndromes/complications MH - Leptospirosis/complications MH - Meningitis/cerebrospinal fluid/*diagnosis/microbiology MH - Meningitis, Pneumococcal MH - Mycoses/complications MH - Nausea/complications MH - Recurrence MH - Splenectomy MH - Time Factors MH - Tuberculosis, Meningeal MH - Virus Diseases MH - Vomiting/complications MH - Wounds and Injuries/complications PT - JOURNAL ARTICLE PT - REVIEW DA - 720626 DP - 1972 Jan IS - 0002-9343 TA - Am J Med PG - 128-40 SB - A SB - M CY - UNITED STATES IP - 1 VI - 52 JC - 3JU EM - 7208 RF - 65 PMID- 4111896 CU - 95 SO - Am J Med 1972 Jan;52(1):128-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72162948 AU - Pannwitz S AU - Uecker E AU - Blohm H TI - [Experiences in porcine leptospirosis campaign with special reference to Leptospira pomona infection] LA - Ger MH - Animal MH - Antibodies/analysis MH - English Abstract MH - Female MH - Germany, East MH - Leptospirosis/epidemiology/prevention & control/*veterinary MH - Male MH - Swine MH - Swine Diseases/epidemiology/*prevention & control PT - JOURNAL ARTICLE DA - 720626 DP - 1971 Dec 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 924-7 CY - GERMANY, EAST IP - 24 VI - 26 JC - NGV EM - 7208 PMID- 5146334 CU - 88 TT - Erfahrungen bei der Bekampfung der Leptospirose der Schweine unter besonderer Berucksichtigung der Leptospira-pomona-Infektion. SO - Monatsh Veterinarmed 1971 Dec 15;26(24):924-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 73001476 AU - Crawford RP AU - Heinemann JM AU - McCulloch WF AU - Diesch SL TI - Human infections associated with waterborne Leptospires, and survival studies on serotype pomona. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Blood/microbiology MH - Child MH - Female MH - Guinea Pigs MH - Hardness MH - Human MH - Hydrogen-Ion Concentration MH - Kidney/microbiology MH - Leptospira/growth & development/*isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*epidemiology/etiology MH - Male MH - Middle Age MH - Time Factors MH - United States MH - Virulence MH - *Water Microbiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 721110 DP - 1971 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1477-84 SB - M CY - UNITED STATES IP - 11 VI - 159 JC - HAV EM - 7301 PMID- 5153868 CU - 90 SO - J Am Vet Med Assoc 1971 Dec 1;159(11):1477-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72144742 AU - Van Peenen PF AU - Light RH AU - Sulianti Saroso J TI - Leptospirosis in wild mammals of Indonesia--recent surveys. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/isolation & purification MH - *Carnivora MH - *Chiroptera MH - Disease Reservoirs MH - Disease Vectors MH - Indonesia MH - *Insectivora MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Rats MH - Rodent Diseases/*epidemiology/microbiology MH - Sciuridae MH - Serotyping PT - JOURNAL ARTICLE DA - 720603 DP - 1971 Dec IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 496-502 SB - M CY - THAILAND IP - 4 VI - 2 JC - UVN EM - 7207 PMID- 5144150 CU - 88 SO - Southeast Asian J Trop Med Public Health 1971 Dec;2(4):496-502 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 72144741 AU - Light RH AU - Nasution R AU - Van Peenen PF TI - Leptospirosis in febrile hospital patients in Djakarta. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Antibodies/isolation & purification MH - Female MH - Fever/*etiology MH - Fever of Unknown Origin/microbiology MH - Human MH - Indonesia MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology/immunology/microbiology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 720603 DP - 1971 Dec IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 493-5 SB - M CY - THAILAND IP - 4 VI - 2 JC - UVN EM - 7207 PMID- 5144149 CU - 88 SO - Southeast Asian J Trop Med Public Health 1971 Dec;2(4):493-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72073395 AU - Negi SK AU - Myers WL AU - Segre D TI - Antibody response of cattle to Leptospira pomona: a hemagglutination test to measure IgG and IgM antibodies. LA - Eng MH - Animal MH - Antibodies/*analysis MH - *Cattle MH - Chromatography, DEAE-Cellulose MH - *Hemagglutination Tests MH - IgG/analysis MH - IgM/analysis MH - Immune Sera MH - Immunoelectrophoresis MH - Immunoglobulins/*analysis MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology MH - Methods MH - Rabbits MH - Sheep MH - Time Factors PT - JOURNAL ARTICLE DA - 720306 DP - 1971 Dec IS - 0002-9645 TA - Am J Vet Res PG - 1907-13 SB - M CY - UNITED STATES IP - 12 VI - 32 JC - 40C EM - 7204 PMID- 5131418 CU - 90 SO - Am J Vet Res 1971 Dec;32(12):1907-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 72066579 AU - Williams RD AU - Morter RL AU - Freeman MJ AU - Lavignette AM TI - Experimental chronic uveitis. Ophthalmic signs following equine leptospirosis. LA - Eng MH - Animal MH - Chorioretinitis/etiology/pathology MH - Fundus Oculi MH - *Horse Diseases/blood/urine MH - Horses MH - Injections, Intraperitoneal MH - Leptospira/isolation & purification MH - Leptospirosis/blood/urine/*veterinary MH - Time Factors MH - Uveitis/etiology/pathology/*veterinary PT - JOURNAL ARTICLE DA - 720223 DP - 1971 Dec IS - 0020-9988 TA - Invest Ophthalmol PG - 948-54 SB - M CY - UNITED STATES IP - 12 VI - 10 JC - GWH EM - 7204 PMID- 5128770 CU - 90 SO - Invest Ophthalmol 1971 Dec;10(12):948-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72162354 AU - Vosta J AU - Tesarik L TI - [Infectious abortions of Leptospira origin in cattle] LA - Cze MH - Abortion, Veterinary/immunology/*microbiology MH - Animal MH - Antibodies/analysis MH - Cattle MH - Cattle Diseases/*immunology MH - English Abstract MH - Female MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/immunology/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/*veterinary PT - JOURNAL ARTICLE DA - 720626 DP - 1971 Dec IS - 0375-8427 TA - Vet Med (Praha) PG - 683-8 SB - M CY - CZECHOSLOVAKIA IP - 11 VI - 16 JC - XBP EM - 7208 PMID- 5004373 CU - 91 TT - Infekcni aborty leptospirozniho puvodu u skotu. SO - Vet Med (Praha) 1971 Dec;16(11):683-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [25 medline neighbors] UI - 73024392 AU - Marcus LC TI - Infectious diseases of reptiles. LA - Eng MH - Abscess/veterinary MH - Aeromonas MH - Algae MH - Animal MH - Animals, Laboratory MH - *Animals, Zoo MH - Encephalomyelitis/veterinary MH - Escherichia MH - Escherichia coli Infections/veterinary MH - Gingivitis, Necrotizing Ulcerative/veterinary MH - Infection/*veterinary MH - Leptospirosis/veterinary MH - Mycobacterium Infections/veterinary MH - Mycoses/veterinary MH - Pneumonia/veterinary MH - *Reptiles MH - Salmonella Infections, Animal/etiology MH - Skin Diseases/veterinary MH - Snakes MH - Turtles PT - JOURNAL ARTICLE PT - REVIEW DA - 721229 DP - 1971 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1626-31 SB - M CY - UNITED STATES IP - 11 VI - 159 JC - HAV EM - 7302 RF - 30 PMID- 4949438 CU - 90 SO - J Am Vet Med Assoc 1971 Dec 1;159(11):1626-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 73001480 AU - Diesch SL TI - Survival of leptospires in cattle manure. LA - Eng MH - Animal MH - *Cattle MH - Cattle Diseases/microbiology MH - Feces/*microbiology MH - Fluorescent Antibody Technique MH - Hamsters MH - Human MH - Hydrogen-Ion Concentration MH - Leptospira/growth & development/immunology/*isolation & purification MH - Leptospirosis/microbiology/veterinary MH - Public Health MH - Seasons MH - Temperature MH - Time Factors MH - Zoonoses PT - JOURNAL ARTICLE DA - 721110 DP - 1971 Dec 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1513-7 SB - M CY - UNITED STATES IP - 11 VI - 159 JC - HAV EM - 7301 PMID- 4949300 CU - 90 SO - J Am Vet Med Assoc 1971 Dec 1;159(11):1513-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 72073422 AU - Stalheim OH TI - Leptospirosis diagnosis by immunofluorescence: improved procedure for antigen preparation. LA - Eng MH - Animal MH - *Antigens MH - Antigens, Bacterial MH - Centrifugation MH - Fluorescent Antibody Technique/*veterinary MH - Leptospira/immunology MH - Leptospirosis/diagnosis/*veterinary MH - Methods MH - Osmium MH - Oxides PT - JOURNAL ARTICLE DA - 720306 DP - 1971 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2107-9 SB - M CY - UNITED STATES IP - 12 VI - 32 JC - 40C EM - 7204 PMID- 4943412 CU - 90 SO - Am J Vet Res 1971 Dec;32(12):2107-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 72115243 AU - Engelhardt K TI - [Combined application of a corticosteroid and antibiotic in experimental leptospirosis] LA - Ger MH - Animal MH - Antibody Formation/*drug effects MH - Body Temperature/drug effects MH - Body Weight/drug effects MH - Drug Combinations MH - English Abstract MH - Leptospira interrogans/*immunology MH - Male MH - Prednisolone/pharmacology MH - Rats MH - Tetracycline/pharmacology MH - Weil's Disease/drug therapy PT - JOURNAL ARTICLE DA - 720501 DP - 1971 Dec IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 461-7 SB - M CY - GERMANY, WEST IP - 4 VI - 218 JC - Y52 EM - 7206 PMID- 4400728 CU - 94 TT - Kombinierte Anwendung eines Corticosteroids und eines Antibiotikums bei der experimentellen Leptospirose. SO - Zentralbl Bakteriol [Orig A] 1971 Dec;218(4):461-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 72073396 AU - Negi SK AU - Myers WL AU - Segre D TI - Antibody response of cattle to Leptospira pomona: response as measured by hemagglutination, microscopic agglutination, and hamster protection tests. LA - Eng MH - *Agglutination Tests MH - Animal MH - Antibodies/*analysis MH - Antibody Formation MH - Bacterial Vaccines/administration & dosage MH - *Cattle MH - Gamma-Globulins/administration & dosage MH - Hamsters MH - *Hemagglutination Tests MH - IgG/administration & dosage/analysis MH - IgM/analysis MH - Immunity, Active MH - Immunity, Maternally-Acquired MH - Injections, Intraperitoneal MH - Injections, Subcutaneous MH - Leptospira/*immunology MH - Time Factors MH - Vaccination PT - JOURNAL ARTICLE DA - 720306 DP - 1971 Dec IS - 0002-9645 TA - Am J Vet Res PG - 1915-20 SB - M CY - UNITED STATES IP - 12 VI - 32 JC - 40C EM - 7204 PMID- 4108773 CU - 95 SO - Am J Vet Res 1971 Dec;32(12):1915-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [77 medline neighbors] UI - 72094915 AU - Pitney SN AU - Doetsch RN TI - Effect of pharmacologically active drugs on the motility of Leptospira interrogans (biflexa). LA - Eng MH - Atropine/pharmacology MH - Barbiturates/pharmacology MH - Caffeine/pharmacology MH - Cell Movement/*drug effects MH - Epinephrine/pharmacology MH - Isoproterenol/pharmacology MH - Leptospira/*drug effects MH - Neostigmine/pharmacology MH - Norepinephrine/pharmacology MH - Physostigmine/pharmacology MH - Picrotoxin/pharmacology MH - Potassium/pharmacology MH - Sodium/pharmacology MH - Strychnine/pharmacology MH - Tubocurarine/pharmacology MH - Tyramine/pharmacology MH - Tyrosine/pharmacology PT - JOURNAL ARTICLE DA - 720405 DP - 1971 Nov 8 IS - 0300-9637 TA - Life Sci [II] PG - 1237-46 SB - M CY - UNITED STATES IP - 21 VI - 10 JC - L68 EM - 7205 PMID- 5138348 SO - Life Sci [II] 1971 Nov 8;10(21):1237-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72265913 AU - Bernasovs'ka EP TI - [Immunoadsorption studies on leptospira strains isolated in the Ukraine] LA - Ukr MH - *Hemadsorption MH - Leptospira/*immunology MH - Ukraine PT - JOURNAL ARTICLE DA - 721019 DP - 1971 Nov-Dec IS - 0026-3664 TA - Mikrobiol Zh PG - 756-7 CY - USSR IP - 6 VI - 33 JC - MZ2 EM - 7212 PMID- 5153560 TT - Rezul'taty imuno-adsorbtsiinoho vyvchennia shtamiv leptospir, vydijenykh na Ukraini. SO - Mikrobiol Zh 1971 Nov-Dec;33(6):756-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 72265912 AU - Mogir'ova LA TI - [Polysaccharide containing fractions of leptospira and possibilities of their applications for generic and specific diagnosis of leptospiroses] LA - Ukr MH - Animal MH - Leptospira/*analysis MH - Leptospirosis/*diagnosis MH - *Polysaccharides, Bacterial PT - JOURNAL ARTICLE DA - 721019 DP - 1971 Nov-Dec IS - 0026-3664 TA - Mikrobiol Zh PG - 754-5 CY - USSR IP - 6 VI - 33 JC - MZ2 EM - 7212 PMID- 5153559 TT - Polisakharydvmisni fraktsii leptospir i perspektyvy ikh zastosuvannia dlia rodospetsyfichnoi diahostyky leptospiroziv. SO - Mikrobiol Zh 1971 Nov-Dec;33(6):754-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 72265911 AU - Zakharenko NI AU - Bernasovs'ka EP TI - [The DNA composition of nitrogenous bases of leptospira strains belonging to different sulfur groups] LA - Ukr MH - DNA/*analysis MH - Leptospira/*analysis/classification MH - Sulfur/analysis PT - JOURNAL ARTICLE DA - 721019 DP - 1971 Nov-Dec IS - 0026-3664 TA - Mikrobiol Zh PG - 753-4 CY - USSR IP - 6 VI - 33 JC - MZ2 EM - 7212 PMID- 5153558 TT - Vyvchennia skladu azotystykh osnov DNK u shtamiv leptospir, iaki nalezhat' do riznykh serohrup. SO - Mikrobiol Zh 1971 Nov-Dec;33(6):753-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 72030833 AU - Cook JE AU - Coles EH AU - Garner FM AU - Luna LG TI - Using scrapings from formalin-fixed tissues to diagnose leptospirosis by fluorescent-antibody techniques. LA - Eng MH - Animal MH - Antigens/analysis MH - Fluoresceins MH - *Fluorescent Antibody Technique MH - Formaldehyde MH - Gelatin MH - Hamsters MH - *Histological Techniques MH - Kidney/microbiology MH - Leptospira MH - Leptospirosis/*diagnosis MH - Liver/microbiology MH - Microscopy, Fluorescence PT - JOURNAL ARTICLE DA - 720110 DP - 1971 Nov IS - 0038-9153 TA - Stain Technol PG - 271-4 SB - M CY - UNITED STATES IP - 6 VI - 46 JC - V06 EM - 7202 PMID- 4940203 CU - 90 SO - Stain Technol 1971 Nov;46(6):271-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72082505 AU - McCaughey WJ AU - Fairley JS TI - Leptospirosis in Irish wildlife. LA - Eng MH - Animal MH - Carnivora MH - Chiroptera MH - *Disease Reservoirs MH - Leptospirosis/epidemiology/*veterinary MH - Mice MH - Northern Ireland MH - Rodent Diseases/epidemiology MH - Shrews PT - JOURNAL ARTICLE DA - 720317 DP - 1971 Oct 16 IS - 0042-4900 TA - Vet Rec PG - 447 SB - M CY - ENGLAND IP - 16 VI - 89 JC - XBS EM - 7205 PMID- 5167393 CU - 88 SO - Vet Rec 1971 Oct 16;89(16):447 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 72187608 AU - Kinebuchi H TI - [Supplementary notes on Leptospira agglutination reaction] LA - Jpn MH - Adult MH - *Agglutination Tests MH - Human MH - Male MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 720726 DP - 1971 Oct IS - 0021-4930 TA - Nippon Saikingaku Zasshi PG - 499-502 CY - JAPAN IP - 10 VI - 26 JC - KHZ EM - 7209 PMID- 5169939 CU - 85 SO - Nippon Saikingaku Zasshi 1971 Oct;26(10):499-502 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 72132281 AU - Hergt R TI - [Tarassov's leptospirosis caused by preparing swine kidneys at home] LA - Ger MH - Adult MH - Animal MH - English Abstract MH - Female MH - Food Poisoning/*complications MH - Human MH - Kidney MH - Leptospirosis/*etiology MH - *Meat MH - Swine PT - JOURNAL ARTICLE DA - 720517 DP - 1971 Oct 1 IS - 0012-0219 TA - Dtsch Gesundheitsw PG - 1903-4 CY - GERMANY, EAST IP - 40 VI - 26 JC - ECG EM - 7207 PMID- 5168890 CU - 85 TT - Tarassov-Leptospirose durch Zubereitung von Schweinenieren im Haushalt. SO - Dtsch Gesundheitsw 1971 Oct 1;26(40):1903-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72111503 AU - Khanna RS AU - Iyer PK TI - Suspected leptospirosis in goats. LA - Eng MH - Animal MH - Autopsy MH - Disease Reservoirs MH - *Goats MH - Human MH - India MH - Kidney MH - Leptospirosis/pathology/prevention & control/*veterinary MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 720426 DP - 1971 Oct IS - 0019-5340 TA - Indian J Med Res PG - 1588-90 CY - INDIA IP - 10 VI - 59 JC - GJF EM - 7206 PMID- 5158996 CU - 88 SO - Indian J Med Res 1971 Oct;59(10):1588-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 72135922 AU - Pletnev VM AU - Mitchenko IK AU - Slobodianiuk MI TI - [Treatment of patients with various forms of leptospirosis] LA - Rus MH - Adult MH - Cardiovascular Diseases/drug therapy MH - English Abstract MH - Female MH - Human MH - Kidney Diseases/drug therapy MH - Leptospirosis/*drug therapy MH - Liver Diseases/drug therapy MH - Male MH - Weil's Disease/drug therapy PT - JOURNAL ARTICLE DA - 720524 DP - 1971 Oct IS - 0049-6804 TA - Vrach Delo PG - 149-52 CY - USSR VI - 10 JC - XLS EM - 7207 PMID- 5142517 TT - Lechenie bol'nykh s razlichnymi formami leptospiroza. SO - Vrach Delo 1971 Oct;10:149-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 72071452 AU - Stalheim OH TI - Viable, avirulent Leptospira interrogans serotype pomona vaccine: preservation in liquid nitrogen. LA - Eng MH - Albumins MH - Ascorbic Acid MH - Bacterial Vaccines/*standards MH - Dimethyl Sulfoxide MH - Drug Storage MH - *Freezing MH - Glycerin MH - *Leptospira/pathogenicity MH - Nitrogen MH - Polysaccharides MH - Serotyping MH - Virulence PT - JOURNAL ARTICLE DA - 720303 DP - 1971 Oct IS - 0003-6919 TA - Appl Microbiol PG - 726-7 SB - M CY - UNITED STATES IP - 4 VI - 22 JC - 6K0 EM - 7204 PMID- 5130436 SO - Appl Microbiol 1971 Oct;22(4):726-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 72091541 AU - Parnas J TI - [Toxins of Leptospira] LA - Ger MH - Animal MH - Cell Line/drug effects MH - Chickens MH - English Abstract MH - Haplorhini MH - Human MH - Leptospira/*pathogenicity MH - Lipids/analysis MH - Tissue Culture MH - Toxins/*analysis/pharmacology PT - JOURNAL ARTICLE DA - 720331 DP - 1971 Oct TA - Zentralbl Veterinarmed [B] PG - 596-603 CY - GERMANY, WEST IP - 8 VI - 18 JC - Y72 EM - 7205 PMID- 5002859 CU - 91 TT - Toxine der Leptospiren. SO - Zentralbl Veterinarmed [B] 1971 Oct;18(8):596-603 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72238839 AU - Dragomir AV AU - Matveeva AA TI - [Leptospira carrier state in animals] LA - Rus MH - Animal MH - Carrier State MH - Leptospirosis/*veterinary MH - Mice MH - Moldova MH - Rats MH - Rodent Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 720919 DP - 1971 Oct IS - 0042-4846 TA - Veterinariia PG - 66-7 CY - USSR VI - 10 JC - XCC EM - 7211 PMID- 4261586 CU - 92 TT - O leptospironositel'stve u zhivotnykh. SO - Veterinariia 1971 Oct;10:66-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 72107070 AU - Tsai CC AU - Sulzer CR TI - Four new leptospiral serotypes isolated from human sources in South Vietnam. LA - Eng MH - Agglutination Tests MH - Fever of Unknown Origin/microbiology MH - Human MH - Immune Sera MH - Leptospira/*classification/immunology/isolation & purification MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology MH - Male MH - Serotyping MH - Vietnam PT - JOURNAL ARTICLE DA - 720419 DP - 1971 Sep IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 313-21 SB - M CY - THAILAND IP - 3 VI - 2 JC - UVN EM - 7206 PMID- 5157925 SO - Southeast Asian J Trop Med Public Health 1971 Sep;2(3):313-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 72265039 AU - Bernasovs'ka EP AU - Matsiuk VM AU - Zakharenko NI TI - [Immunochemical study of polysaccharide containing fractions obtained from leptospira by Fuller's method] LA - Ukr MH - English Abstract MH - Hemagglutination Tests MH - Human MH - Immunochemistry MH - Leptospira/*immunology MH - Leptospirosis/diagnosis MH - Polysaccharides, Bacterial/*analysis PT - JOURNAL ARTICLE DA - 721019 DP - 1971 Sep-Oct IS - 0026-3664 TA - Mikrobiol Zh PG - 553-7 CY - USSR IP - 5 VI - 33 JC - MZ2 EM - 7212 PMID- 5153487 TT - Imunokhimichne vyvchennia polisakharydvmicnykh fraktsii z leptospir. SO - Mikrobiol Zh 1971 Sep-Oct;33(5):553-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [168 medline neighbors] UI - 72213018 AU - Nicolescu M AU - Oprisan R TI - The antileptospira antibodies in apparently healthy horses. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/*analysis MH - Complement Fixation Tests MH - Horses MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 720819 DP - 1971 Sep-Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 335-40 CY - ROMANIA IP - 3 VI - 30 JC - 8EM EM - 7210 PMID- 5150496 SO - Arch Roum Pathol Exp Microbiol 1971 Sep-Dec;30(3):335-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 72004028 AU - Carlos ER AU - Kundin WD AU - Watten RH AU - Tsai CC AU - Irving GS AU - Carlos ET AU - Directo AC TI - Leptospirosis in the Philippines: canine studies. LA - Eng MH - Animal MH - Antibodies/analysis MH - Dog Diseases/diagnosis/*epidemiology/immunology MH - Dogs MH - Leptospira/classification/isolation & purification MH - Leptospirosis/diagnosis/epidemiology/immunology/*veterinary MH - Pedigree/veterinary MH - Philippines MH - Serotyping/veterinary PT - JOURNAL ARTICLE DA - 711202 DP - 1971 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1451-4 SB - M CY - UNITED STATES IP - 9 VI - 32 JC - 40C EM - 7201 PMID- 5106720 CU - 88 SO - Am J Vet Res 1971 Sep;32(9):1451-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 72013419 AU - Borg-Petersen C TI - A thermo-labile antigen in the Leptospira strain Ictero No. I. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens/*isolation & purification MH - Heat MH - Leptospira/*immunology MH - Leptospira interrogans/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 711212 DP - 1971 Sep IS - 0041-3232 TA - Trop Geogr Med PG - 282-5 SB - M CY - NETHERLANDS IP - 3 VI - 23 JC - WGJ EM - 7201 PMID- 5098997 SO - Trop Geogr Med 1971 Sep;23(3):282-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72004031 AU - Tripathy DN AU - Evans LB AU - Hanson LE TI - Isolation of Leptospira andamana from surface water. LA - Eng MH - Agglutination Tests MH - Animal MH - Bacteriological Techniques MH - Hamsters MH - Illinois MH - Immune Sera/analysis MH - Leptospira/classification/*isolation & purification MH - Serotyping MH - Species Specificity MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 711202 DP - 1971 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1463-4 SB - M CY - UNITED STATES IP - 9 VI - 32 JC - 40C EM - 7201 PMID- 4937619 CU - 90 SO - Am J Vet Res 1971 Sep;32(9):1463-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 72004029 AU - Carlos ER AU - Kundin WD AU - Watten RH AU - Tsai CC AU - Irving GS AU - Carlos ET AU - Directo AC TI - Leptospirosis in the Philippines: feline studies. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Bacteriological Techniques MH - Cat Diseases/diagnosis/*epidemiology/immunology MH - Cats MH - Immune Sera/analysis MH - Leptospira/immunology/isolation & purification MH - Leptospirosis/diagnosis/epidemiology/immunology/*veterinary MH - Philippines MH - Serotyping/veterinary MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 711202 DP - 1971 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1455-6 SB - M CY - UNITED STATES IP - 9 VI - 32 JC - 40C EM - 7201 PMID- 4937618 CU - 90 SO - Am J Vet Res 1971 Sep;32(9):1455-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 72087418 AU - Babudieri B TI - Isolation and study of antigenic mutants of saprophytic and pathogenic Leptospiras. LA - Eng MH - Antigens/analysis MH - Bacteriological Techniques MH - Genetics, Microbial MH - Immune Sera/*pharmacology MH - Leptospira/drug effects/*growth & development/isolation & purification MH - *Mutation PT - JOURNAL ARTICLE DA - 720324 DP - 1971 Sep IS - 0300-9688 TA - Zentralbl Bakteriol [Orig A] PG - 75-86 SB - M CY - GERMANY, WEST IP - 1 VI - 218 JC - Y52 EM - 7205 PMID- 4400129 CU - 94 SO - Zentralbl Bakteriol [Orig A] 1971 Sep;218(1):75-86 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 74280242 AU - Tredici E AU - Crisafulli G AU - Loreti G TI - [On the specificity of the complement-fixing antigen for Leptospira. Studies on syphilitic sera] LA - Ita MH - *Antigens, Bacterial MH - *Complement Fixation Tests MH - English Abstract MH - Epitopes MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis MH - Syphilis/blood MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE DA - 741001 DP - 1971 Sep IS - 0033-4979 TA - Quad Sclavo Diagn PG - 656-60 CY - ITALY IP - 3 VI - 7 JC - QLU EM - 7411 RO - O:46 RO - C:01 PMID- 4135850 CU - 95 TT - Sulla specificita dell'antigene F.C. per le leptospire. Ricerche esequite su sieri di luetici EA - A SO - Quad Sclavo Diagn 1971 Sep;7(3):656-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71287620 AU - Nityananda K AU - Sulzer CR TI - A new serotype of Leptospira belonging to the autumnalis serogroup. LA - Eng MH - Agglutination Tests MH - Cross Reactions MH - Human MH - Leptospira/*classification MH - Leptospirosis/*microbiology MH - Serotyping MH - Sri Lanka PT - JOURNAL ARTICLE DA - 711112 DP - 1971 Aug IS - 0022-5304 TA - J Trop Med Hyg PG - 184-6 SB - M CY - ENGLAND IP - 8 VI - 74 JC - KAV EM - 7112 PMID- 5570126 SO - J Trop Med Hyg 1971 Aug;74(8):184-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 71280566 AU - Addison K TI - Leptospirosis (Red-water fever). LA - Eng MH - Leptospirosis MH - Nursing PT - JOURNAL ARTICLE DA - 711030 DP - 1971 Aug TA - N Z Nurs J PG - 8-11 SB - N CY - NEW ZEALAND IP - 8 VI - 64 JC - OBT EM - 7112 PMID- 5284601 CU - 89 LI - N SO - N Z Nurs J 1971 Aug;64(8):8-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 72192052 AU - Liubashenko SIa AU - Malakhov IuA AU - Seregin IG AU - Samokhvalov AP AU - Stepanenko PP TI - [Vaccination of swine against leptospirosis] LA - Rus MH - Age Factors MH - Animal MH - Antibody Formation MH - Hamsters MH - Leptospirosis/prevention & control/*veterinary MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 720729 DP - 1971 Aug IS - 0042-4846 TA - Veterinariia PG - 46-9 CY - USSR VI - 8 JC - XCC EM - 7209 PMID- 5169983 CU - 85 TT - Razrabotka rezhimov vaktsinatsii svinei protiv leptospirozoa. SO - Veterinariia 1971 Aug;8:46-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 73032678 AU - Alexander AD AU - Wood G AU - Yancey F AU - Byrne RJ AU - Yager RH TI - Cross-neutralization of leptospiral hemolysins from different serotypes. LA - Eng MH - Albuminuria MH - Animal MH - Antibodies, Bacterial/analysis MH - Cross Reactions MH - Erythrocytes/immunology MH - Hamsters MH - Hematocrit MH - Hemoglobins/analysis MH - Hemoglobinuria MH - *Hemolysins/analysis/isolation & purification MH - Leptospira/*immunology MH - Leptospira canicola/*immunology MH - Leptospirosis/immunology/veterinary MH - Neutralization Tests MH - Rabbits/immunology MH - Sheep PT - JOURNAL ARTICLE DA - 730105 DP - 1971 Aug IS - 0019-9567 TA - Infect Immun PG - 154-9 SB - M CY - UNITED STATES IP - 2 VI - 4 JC - GO7 EM - 7302 PMID- 5154879 SO - Infect Immun 1971 Aug;4(2):154-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 73004482 AU - Bernasovs'ka EP AU - Matsiuk VM TI - [Isolation of polysaccharide containing fractions of Leptospira by the Fuller method] LA - Ukr MH - Acetone/pharmacology MH - English Abstract MH - Formamides/pharmacology MH - Leptospira/*analysis MH - Polysaccharides, Bacterial/*isolation & purification PT - JOURNAL ARTICLE DA - 721115 DP - 1971 Aug-Sep IS - 0026-3664 TA - Mikrobiol Zh PG - 454-9 CY - USSR IP - 4 VI - 33 JC - MZ2 EM - 7301 PMID- 5153984 TT - Vydilennia polisakharydvmisnykh fraktsii leptospir za metodom fullera. SO - Mikrobiol Zh 1971 Aug-Sep;33(4):454-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72005085 AU - Davidson KR TI - Leptospira hardjo infection in man associated with an outbreak in a dairy herd. LA - Eng MH - Abortion, Veterinary/epidemiology MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/*epidemiology MH - Disease Outbreaks/veterinary MH - Female MH - Human MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Pregnancy MH - *Zoonoses PT - JOURNAL ARTICLE DA - 711202 DP - 1971 Aug IS - 0005-0423 TA - Aust Vet J PG - 408 SB - M CY - AUSTRALIA IP - 8 VI - 47 JC - 9IE EM - 7201 RO - M:CNR PMID- 5106801 LR - 931119 CU - 88 SO - Aust Vet J 1971 Aug;47(8):408 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 72128872 AU - Zubekhin AV TI - [Immunity in swine in single and complex vaccination] LA - Rus MH - Agglutination Tests MH - Animal MH - Erysipelothrix Infections/prevention & control MH - Hog Cholera/prevention & control MH - Leptospirosis/prevention & control/veterinary MH - Methods MH - Paratyphoid Fever/prevention & control/veterinary MH - Pasteurella Infections/prevention & control/veterinary MH - Pseudorabies/prevention & control MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 720511 DP - 1971 Aug IS - 0042-4846 TA - Veterinariia PG - 41-3 CY - USSR VI - 9 JC - XCC EM - 7207 PMID- 5003843 CU - 91 TT - Immunitet u svinei pri mono- i kompleksnoi vaktsinatsii. SO - Veterinariia 1971 Aug;9:41-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [125 medline neighbors] UI - 71276712 AU - Walters JH TI - Malaria and other febrile conditions. LA - Eng MH - Brucellosis/diagnosis MH - Diagnosis, Differential MH - Emigration and Immigration MH - Fever/*diagnosis/etiology MH - Fever of Unknown Origin/diagnosis MH - Human MH - Leishmaniasis, Visceral/diagnosis MH - Leptospirosis/diagnosis MH - Liver Abscess, Amebic/diagnosis MH - Malaria/*diagnosis MH - Paratyphoid Fever/diagnosis MH - Syphilis/diagnosis MH - Trypanosomiasis, African/diagnosis MH - Typhoid/diagnosis MH - Typhus, Epidemic Louse-Borne/diagnosis PT - JOURNAL ARTICLE DA - 711026 DP - 1971 Aug IS - 0032-6518 TA - Practitioner PG - 147-53 SB - M CY - ENGLAND IP - 238 VI - 207 JC - PHQ EM - 7112 PMID- 4998411 CU - 91 SO - Practitioner 1971 Aug;207(238):147-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 71254161 AU - Gsell HO Jr AU - Olafsson A AU - Sonnabend W AU - Breer C AU - Bachmann C TI - [Intrauterine leptospirosis pomona. 1st reported case of an intrauterine transmitted and cured leptospirosis] LA - Ger MH - Acidosis/complications MH - Adult MH - Agglutination MH - Agglutination Tests MH - Antibodies MH - Antigen-Antibody Reactions MH - Cesarean Section MH - English Abstract MH - Female MH - Fluorescent Antibody Technique MH - Gestational Age MH - Human MH - IgG/analysis MH - IgM/analysis MH - Infant, Newborn MH - *Infant, Premature, Diseases MH - Jaundice, Neonatal MH - Leptospira/isolation & purification MH - Leptospirosis/*congenital/complications/diagnosis/drug therapy/immunology/urine MH - Male MH - Maternal-Fetal Exchange MH - Meningitis/congenital MH - Mercaptoethanol/administration & dosage MH - Pneumonia/congenital MH - Pregnancy MH - Pregnancy Complications, Infectious MH - Septicemia/congenital PT - JOURNAL ARTICLE DA - 710922 DP - 1971 Jul 30 IS - 0012-0472 TA - Dtsch Med Wochenschr PG - 1263-8 SB - M CY - GERMANY, WEST IP - 31 VI - 96 JC - ECL EM - 7111 PMID- 4934402 CU - 90 TT - Intrauterine Leptospirosis pomona. Erster berichtter Fall einer intrauterin ubertragenen und geheilten Leptospirose. SO - Dtsch Med Wochenschr 1971 Jul 30;96(31):1263-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72100866 AU - McIlhattan TJ AU - Martin JW AU - Wagner RJ AU - Iversen JO TI - Isolation of Leptospira pomona from a naturally infected California sea lion, Sonoma County, California. LA - Eng MH - Animal MH - California MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/pathology/*veterinary MH - Male MH - *Pinnipedia MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 720411 DP - 1971 Jul IS - 0090-3558 TA - J Wildl Dis PG - 195-7 SB - M CY - UNITED STATES IP - 3 VI - 7 JC - KEM EM - 7206 PMID- 5156488 SO - J Wildl Dis 1971 Jul;7(3):195-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 72100863 AU - Kingscote BF TI - Leptospires in finger nail clams. LA - Eng MH - Animal MH - Deer MH - Disease Vectors MH - Gerbillinae MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/veterinary MH - *Mollusca MH - Ontario PT - JOURNAL ARTICLE DA - 720411 DP - 1971 Jul IS - 0090-3558 TA - J Wildl Dis PG - 178-85 SB - M CY - UNITED STATES IP - 3 VI - 7 JC - KEM EM - 7206 PMID- 5156485 CU - 88 SO - J Wildl Dis 1971 Jul;7(3):178-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 72261714 AU - Parnas J TI - [Ecology of leptospirosis and the symptoms caused by L. grippotyphosa and L. polonica as a problem of rural medicine] LA - Ita MH - Disease Reservoirs MH - Ecology MH - English Abstract MH - Human MH - Leptospira/isolation & purification MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology MH - Poland MH - *Rural Health MH - Weil's Disease PT - JOURNAL ARTICLE DA - 721012 DP - 1971 Jul-Aug IS - 0003-472X TA - Ann Sclavo PG - 477-89 CY - ITALY IP - 4 VI - 13 JC - 65C EM - 7212 PMID- 5153321 CU - 88 TT - L'ecologia delle leptospirosi e la sintomatologia da L. grippotyphosa e da L. polonica come problema di medicina rurale. SO - Ann Sclavo 1971 Jul-Aug;13(4):477-89 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 71227640 AU - Tripathy DN AU - Hanson LE TI - Agar overlay method for growth of leptospires in solid medium. LA - Eng MH - Agar MH - *Bacteriological Techniques MH - Leptospira/*growth & development/isolation & purification MH - Methods MH - Water Microbiology PT - JOURNAL ARTICLE DA - 710811 DP - 1971 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1125-7 SB - M CY - UNITED STATES IP - 7 VI - 32 JC - 40C EM - 7110 PMID- 4932708 CU - 90 SO - Am J Vet Res 1971 Jul;32(7):1125-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 71282954 AU - Tong MJ AU - Rosenberg EB AU - Votteri BA AU - Tsai CC TI - Immunological response in leptospirosis. Report of three cases. LA - Eng MH - Adolescence MH - Adult MH - *Antibody Formation MH - Complement Fixation Tests MH - Fever/complications MH - Gamma-Globulins/*analysis MH - Human MH - IgA/analysis/cerebrospinal fluid MH - IgG/analysis/cerebrospinal fluid MH - Immunoglobulins/analysis/cerebrospinal fluid MH - Leptospirosis/*immunology MH - Male MH - Meningitis/complications MH - *Military Medicine MH - Ultracentrifugation MH - United States MH - Vietnam PT - JOURNAL ARTICLE DA - 711105 DP - 1971 Jul IS - 0002-9637 TA - Am J Trop Med Hyg PG - 625-30 SB - A SB - M CY - UNITED STATES IP - 4 VI - 20 JC - 3ZQ EM - 7112 PMID- 4105463 CU - 95 SO - Am J Trop Med Hyg 1971 Jul;20(4):625-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71276615 AU - Davidson KR TI - Leptospira hardjo infection in man. LA - Eng MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Outbreaks/veterinary MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology/microbiology/veterinary MH - Male MH - Species Specificity MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 711026 DP - 1971 Jun 19 IS - 0025-729X TA - Med J Aust PG - 1350 SB - M CY - AUSTRALIA IP - 25 VI - 1 JC - M26 EM - 7112 PMID- 5105763 CU - 88 SO - Med J Aust 1971 Jun 19;1(25):1350 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71190217 AU - Vedros NA AU - Smith AW AU - Schonewald J AU - Migaki G AU - Hubbard RC TI - Leptospirosis epizootic among California sea lions. LA - Eng MH - Animal MH - California MH - Disease Outbreaks/*veterinary MH - Guinea Pigs MH - Kidney/*microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/immunology/pathology/*veterinary MH - *Pinnipedia PT - JOURNAL ARTICLE DA - 710706 DP - 1971 Jun 18 IS - 0036-8075 TA - Science PG - 1250-1 SB - M CY - UNITED STATES IP - 989 VI - 172 JC - UJ7 EM - 7108 PMID- 5576161 SO - Science 1971 Jun 18;172(989):1250-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 71280383 AU - Cheah JS AU - Ransome GA TI - The erythrocyte sedimentation rate in leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Bilirubin/blood MH - *Blood Sedimentation MH - Child MH - Erythrocytes MH - Female MH - Human MH - Leptospirosis/*blood/diagnosis MH - Male MH - Middle Age MH - Urea/blood PT - JOURNAL ARTICLE DA - 711030 DP - 1971 Jun 5 IS - 0025-729X TA - Med J Aust PG - 1233-4 SB - M CY - AUSTRALIA IP - 23 VI - 1 JC - M26 EM - 7112 PMID- 5567220 SO - Med J Aust 1971 Jun 5;1(23):1233-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71291292 AU - Chulovskii IK TI - [Distribution and immunologic structure of the population in relation to leptospiroses in Western Siberia] LA - Rus MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Middle Age MH - Siberia PT - JOURNAL ARTICLE DA - 711116 DP - 1971 Jun TA - Zh Mikrobiol Epidemiol Immunobiol PG - 109-13 SB - M CY - USSR IP - 7 VI - 48 JC - Y9O EM - 7112 PMID- 5571356 CU - 89 TT - Izuchenie rasprostraneniia i immunologicheskoi struktury naseleniia v otnoshenii leptospirozov v Zapadnoi Sibiri. SO - Zh Mikrobiol Epidemiol Immunobiol 1971 Jun;48(7):109-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71240418 AU - Hanson LE AU - Reynolds HA AU - Evans LB TI - Leptospirosis in swine caused by serotype grippotyphosa. LA - Eng MH - Abortion, Veterinary/etiology MH - Agglutination Tests MH - Animal MH - Blood/microbiology MH - Body Temperature MH - Female MH - Fetal Death/etiology/veterinary MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/pathology/*veterinary MH - Placenta/microbiology MH - Pregnancy MH - Pregnancy Complications, Infectious/veterinary MH - Serotyping/veterinary MH - Species Specificity MH - Swine MH - Swine Diseases/complications/etiology/*microbiology/pathology MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 710903 DP - 1971 Jun IS - 0002-9645 TA - Am J Vet Res PG - 855-60 SB - M CY - UNITED STATES IP - 6 VI - 32 JC - 40C EM - 7110 PMID- 5556829 SO - Am J Vet Res 1971 Jun;32(6):855-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 71240417 AU - Stalheim OH TI - Duration of immunity in cattle in response to a viable, avirulent Leptospira pomona vaccine. LA - Eng MH - Agglutination Tests/veterinary MH - Animal MH - Antigens/analysis MH - Cattle MH - Cattle Diseases/*immunology MH - Female MH - Kidney/microbiology MH - Kidney Diseases/microbiology/veterinary MH - Leptospira/*immunology/isolation & purification MH - Leptospirosis/immunology/veterinary MH - Male MH - Time Factors MH - Urine/microbiology MH - Viral Vaccines/*administration & dosage PT - JOURNAL ARTICLE DA - 710903 DP - 1971 Jun IS - 0002-9645 TA - Am J Vet Res PG - 851-4 SB - M CY - UNITED STATES IP - 6 VI - 32 JC - 40C EM - 7110 PMID- 5556828 CU - 90 SO - Am J Vet Res 1971 Jun;32(6):851-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 72162580 AU - Straton C AU - Bercovici C AU - Straton A TI - [A natural leptospira reservoir in the lower Carpathian and neighboring zone of North Moldavia] LA - Fre MH - Animal MH - Antibodies/analysis MH - Disease Reservoirs/epidemiology/*veterinary MH - English Abstract MH - Insectivora MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Rodentia MH - Romania MH - Seasons PT - JOURNAL ARTICLE DA - 720626 DP - 1971 Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 273-9 CY - ROMANIA IP - 2 VI - 30 JC - 8EM EM - 7208 PMID- 5146298 CU - 88 TT - Etude du reservoir naturel de leptospires dans la zone sous-karpatique et limitrophf du Nord de la Moldavie. SO - Arch Roum Pathol Exp Microbiol 1971 Jun;30(2):273-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 72090315 AU - Famatiga EG TI - Leptospira study on fevers on unknown origin in the Philippines. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Agglutination Tests MH - Child MH - Child, Preschool MH - Female MH - Fever/*microbiology MH - Fever of Unknown Origin/microbiology MH - Human MH - Leptospira/classification/*isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/epidemiology MH - Male MH - Middle Age MH - Occupations MH - Philippines MH - Sex Factors PT - JOURNAL ARTICLE DA - 720330 DP - 1971 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 153-63 SB - M CY - THAILAND IP - 2 VI - 2 JC - UVN EM - 7205 PMID- 5136707 CU - 88 SO - Southeast Asian J Trop Med Public Health 1971 Jun;2(2):153-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72090314 AU - Carlos ER AU - Kundin WD AU - Tsai CC AU - Watten RH AU - Irving GS AU - Villanueva C TI - Leptospirosis in the Philippines. VII. Serologic and isolation studies on horses. LA - Eng MH - Agglutination Tests MH - Animal MH - *Horse Diseases MH - Horses MH - Leptospira/isolation & purification/pathogenicity MH - Leptospirosis/diagnosis/*veterinary MH - Philippines PT - JOURNAL ARTICLE DA - 720330 DP - 1971 Jun IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 151-2 SB - M CY - THAILAND IP - 2 VI - 2 JC - UVN EM - 7205 PMID- 5136706 SO - Southeast Asian J Trop Med Public Health 1971 Jun;2(2):151-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72027775 AU - Pupkevich Diamant IaS TI - [Functional state of the liver in leptospiral diseases] LA - Rus MH - Adolescence MH - Adult MH - English Abstract MH - Female MH - Human MH - Leptospirosis/metabolism/*physiopathology MH - Liver/*physiopathology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 720105 DP - 1971 Jun IS - 0023-2149 TA - Klin Med (Mosk) PG - 114-20 CY - USSR IP - 6 VI - 49 JC - KW2 EM - 7202 PMID- 5114132 TT - O funktsional'nom sostoianii pecheni pri leptospiroznykh zabolevaniiakh. SO - Klin Med (Mosk) 1971 Jun;49(6):114-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 72015658 AU - Ho-Ping-Kong H AU - Ragbeer MM AU - Barrow O AU - Ward EE AU - Alleyne GA TI - Peritoneal dialysis in severe leptospiral renal failure. LA - Eng MH - Adult MH - Aged MH - Biopsy MH - Female MH - Human MH - Kidney/pathology MH - Kidney Failure, Acute/etiology/pathology/*therapy MH - Kidney Function Tests MH - Leptospirosis/complications/*therapy MH - Male MH - Peritoneal Dialysis PT - JOURNAL ARTICLE DA - 711216 DP - 1971 Jun IS - 0043-3144 TA - West Indian Med J PG - 76-82 CY - JAMAICA IP - 2 VI - 20 JC - XN4 EM - 7201 PMID- 5110484 SO - West Indian Med J 1971 Jun;20(2):76-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 71283829 AU - Tsai CC AU - Fresh JW TI - Leptospires in the Hebdomadis and Pomona serogroups from mongooses in Tqiwan. LA - Eng MH - Animal MH - Animal Diseases/*epidemiology MH - *Carnivora MH - Female MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Serotyping MH - Species Specificity MH - Taiwan PT - JOURNAL ARTICLE DA - 711105 DP - 1971 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 201-3 SB - M CY - NETHERLANDS IP - 2 VI - 23 JC - WGJ EM - 7112 PMID- 5106018 CU - 88 SO - Trop Geogr Med 1971 Jun;23(2):201-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72001886 AU - Mitchenko IK AU - Pletnev VM AU - Slobodianiuk MI TI - [Some clinical characteristics of leptospirosis] LA - Rus MH - Adult MH - Diagnostic Errors MH - English Abstract MH - Human MH - Leptospirosis/classification/complications/*diagnosis MH - Male PT - JOURNAL ARTICLE DA - 711130 DP - 1971 Jun IS - 0049-6804 TA - Vrach Delo PG - 138-42 CY - USSR IP - 6 JC - XLS EM - 7201 PMID- 5093577 TT - Nekotorye klinicheskie osobennosti leptospirozov. SO - Vrach Delo 1971 Jun;(6):138-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [15 medline neighbors] UI - 71240416 AU - Stalheim OH TI - Virulent and avirulent Leptospires: biochemical activities and survival in blood. LA - Eng MH - Aminopeptidases/metabolism MH - Animal MH - Antibody Formation MH - Bacteriological Techniques MH - Blood Bactericidal Activity MH - Cattle MH - Cattle Diseases/microbiology MH - Chemistry, Physical MH - Choline/metabolism MH - Complement Fixation Tests/veterinary MH - Esterases/metabolism MH - Glycerylphosphorylcholine/metabolism MH - Hamsters MH - Hemolysis MH - Hydrolysis MH - Immune Sera MH - Leptospira/enzymology/immunology/metabolism/*pathogenicity MH - Lipase/metabolism MH - Phosphatidylcholines/metabolism MH - Phosphatidylethanolamines/metabolism MH - Phospholipids/metabolism MH - Rabbits MH - Rodent Diseases/microbiology MH - Swine MH - Swine Diseases/microbiology MH - Virulence PT - JOURNAL ARTICLE DA - 710903 DP - 1971 Jun IS - 0002-9645 TA - Am J Vet Res PG - 843-9 SB - M CY - UNITED STATES IP - 6 VI - 32 JC - 40C EM - 7110 PMID- 4933876 CU - 90 SO - Am J Vet Res 1971 Jun;32(6):843-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 71203809 AU - Whitmore JT AU - Cerda JJ AU - Offutt RG TI - Urban leptospirosis presenting as afebrile jaundice. LA - Eng MH - Diagnosis, Differential MH - Human MH - Jaundice/diagnosis/*etiology MH - Leptospira interrogans MH - Leptospirosis/*complications/diagnosis/etiology/immunology MH - Male MH - Middle Age MH - Water Pollution MH - Weil's Disease/diagnosis/etiology PT - JOURNAL ARTICLE DA - 710715 DP - 1971 May IS - 0002-9211 TA - Am J Dig Dis PG - 455-9 SB - A SB - M CY - UNITED STATES IP - 5 VI - 16 JC - 3G6 EM - 7109 PMID- 5578519 SO - Am J Dig Dis 1971 May;16(5):455-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72052207 AU - Mailloux M TI - [Results of 5-years of serodiagnosis in leptospirosis in Morocco] LA - Fre MH - English Abstract MH - Human MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/complications/*diagnosis/epidemiology/immunology/microbiol ogy MH - Morocco MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 720209 DP - 1971 May-Jun IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 310-6 SB - M CY - FRANCE IP - 3 VI - 64 JC - C4G EM - 7203 PMID- 5171391 CU - 88 TT - Bilan de cinq annees de serodiagnostics de leptospiroses au Maroc. SO - Bull Soc Pathol Exot Filiales 1971 May-Jun;64(3):310-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 72052206 AU - Mailloux M AU - Richard C TI - [Existence of a phosphatase activity in certain leptospires] LA - Fre MH - Acid Phosphatase/*metabolism MH - English Abstract MH - Leptospira/classification/*enzymology MH - Leptospira canicola/enzymology MH - Leptospira interrogans/enzymology PT - JOURNAL ARTICLE DA - 720209 DP - 1971 May-Jun IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 305-10 SB - M CY - FRANCE IP - 3 VI - 64 JC - C4G EM - 7203 PMID- 5171390 CU - 86 TT - Existence d'une activite phosphatasique chez certains leptospires. SO - Bull Soc Pathol Exot Filiales 1971 May-Jun;64(3):305-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 72052205 AU - Sohrabi A TI - Leptospirosis in the central coastal region of the Caspian Sea. LA - Eng MH - Animal MH - Disease Outbreaks MH - Disease Reservoirs MH - Goats MH - Human MH - Iran MH - Leptospirosis/*epidemiology/immunology/veterinary MH - Mice MH - Rats MH - Sheep MH - Sheep Diseases/etiology/immunology MH - Water Microbiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 720209 DP - 1971 May-Jun IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 301-4 SB - M CY - FRANCE IP - 3 VI - 64 JC - C4G EM - 7203 PMID- 5171389 CU - 88 SO - Bull Soc Pathol Exot Filiales 1971 May-Jun;64(3):301-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 72029784 AU - Maronpot RR AU - Barsoum IS AU - Ezzat E TI - Canine leptospirosis in Cairo. LA - Eng MH - Animal MH - Antibodies/*analysis MH - Dog Diseases/*epidemiology/immunology MH - Dogs MH - Egypt MH - Hemagglutination Tests MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/immunology/*veterinary MH - Nephritis, Interstitial/epidemiology/immunology/*veterinary MH - Serotyping PT - JOURNAL ARTICLE DA - 720108 DP - 1971 May IS - 0022-1899 TA - J Infect Dis PG - 548-50 SB - A SB - M CY - UNITED STATES IP - 5 VI - 123 JC - IH3 EM - 7202 PMID- 5165538 CU - 88 SO - J Infect Dis 1971 May;123(5):548-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 71233811 AU - Jack WD 2d AU - Spickard WA Jr TI - Laboratory acquired leptospirosis. LA - Eng MH - Adult MH - Animal MH - Animals, Laboratory MH - Case Report MH - Dog Diseases/complications MH - Dogs MH - Human MH - Leptospira canicola MH - Leptospirosis/*etiology/veterinary MH - Male MH - Specimen Handling PT - JOURNAL ARTICLE DA - 710820 DP - 1971 May IS - 0040-3318 TA - J Tenn Med Assoc PG - 423-4 CY - UNITED STATES IP - 5 VI - 64 JC - K7J EM - 7110 PMID- 5104651 CU - 85 SO - J Tenn Med Assoc 1971 May;64(5):423-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 71205868 AU - Dobson KJ TI - Eradication of leptospirosis from two commercial piggeries in South Australia. LA - Eng MH - Agglutination Tests MH - Animal MH - Leptospirosis/prevention & control/*veterinary MH - Streptomycin/*therapeutic use MH - Swine MH - Swine Diseases/drug therapy/immunology/*prevention & control PT - JOURNAL ARTICLE DA - 710720 DP - 1971 May IS - 0005-0423 TA - Aust Vet J PG - 186-8 SB - M CY - AUSTRALIA IP - 5 VI - 47 JC - 9IE EM - 7109 PMID- 5103871 CU - 85 SO - Aust Vet J 1971 May;47(5):186-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 71217570 AU - Stoenner HG TI - Differential diagnosis of leptospirosis in man. LA - Eng MH - Diagnosis, Differential MH - Human MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 710804 DP - 1971 May IS - 0035-760X TA - Rocky Mt Med J PG - 25-9 CY - UNITED STATES IP - 5 VI - 68 JC - TWX EM - 7109 PMID- 5088138 SO - Rocky Mt Med J 1971 May;68(5):25-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71185531 AU - Henry RA AU - Johnson RC AU - Bohlool BB AU - Schmidt EL TI - Detection of Leptospira in soil and water by immunofluorescence staining. LA - Eng MH - Animal MH - Fluoresceins MH - *Fluorescent Antibody Technique MH - Immune Sera MH - Leptospira/*isolation & purification MH - Rabbits MH - *Soil Microbiology MH - Thiocyanates MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 710630 DP - 1971 May IS - 0003-6919 TA - Appl Microbiol PG - 953-6 SB - M CY - UNITED STATES IP - 5 VI - 21 JC - 6K0 EM - 7108 PMID- 4930040 CU - 90 SO - Appl Microbiol 1971 May;21(5):953-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71258333 AU - Tagi-Zade TA AU - Dzhabrailova FB AU - Alekperov FP TI - [Epidemiology of leptospirosis in South-Western Azerbaijan] LA - Rus MH - Animal MH - Azerbaijan MH - Cattle MH - Cattle Diseases/*epidemiology MH - English Abstract MH - Leptospirosis/*epidemiology/*veterinary MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 710929 DP - 1971 May TA - Zh Mikrobiol Epidemiol Immunobiol PG - 19-22 SB - M CY - USSR IP - 5 VI - 48 JC - Y9O EM - 7111 PMID- 4254390 CU - 92 TT - K epidemiologii leptospirozov v Iugo-Zapadnom Azerbaidzhane. SO - Zh Mikrobiol Epidemiol Immunobiol 1971 May;48(5):19-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71226865 AU - Liceras de Hidalgo J AU - Hidalgo R AU - Aznaran G TI - [Leptospirosis in animals slaughtered in Chimbote, Peru] LA - Spa MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - *Disease Reservoirs MH - English Abstract MH - Human MH - Leptospirosis/epidemiology/*veterinary MH - Peru MH - Serodiagnosis MH - Sheep MH - Sheep Diseases/*epidemiology MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 710810 DP - 1971 May IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 429-35 CY - UNITED STATES IP - 5 VI - 70 JC - AGG EM - 7110 PMID- 4253496 CU - 92 TT - Leptospirosis en animales beneficiados en Chimbote, Peru. SO - Bol Oficina Sanit Panam 1971 May;70(5):429-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71151325 AU - Zack MB AU - Barr AB AU - Sinaly NP TI - Leptospirosis in city slum. Clinical and epidemiologic aspects. LA - Eng MH - Case Report MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - New York City MH - Poverty MH - Urban Population PT - JOURNAL ARTICLE DA - 710516 DP - 1971 Apr 15 IS - 0028-7628 TA - N Y State J Med PG - 880-3 CY - UNITED STATES IP - 8 VI - 71 JC - OBA EM - 7107 PMID- 5279358 CU - 88 SO - N Y State J Med 1971 Apr 15;71(8):880-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71227268 AU - Pannwitz S AU - Meissner R TI - [Incidence of Brucella and Leptospira infections in dogs] LA - Ger MH - Animal MH - Brucellosis/epidemiology/*veterinary MH - Cattle MH - Disease Reservoirs/veterinary MH - Dog Diseases/*epidemiology MH - Dogs MH - English Abstract MH - Germany, East MH - Leptospirosis/epidemiology/*veterinary MH - Rodentia PT - JOURNAL ARTICLE DA - 710810 DP - 1971 Apr 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 313-6 CY - GERMANY, EAST IP - 8 VI - 26 JC - NGV EM - 7110 PMID- 5089003 CU - 88 TT - Untersuchungen zum Vorkommen von Brucellen- und Leptospireninfektionen bei Hunden. SO - Monatsh Veterinarmed 1971 Apr 15;26(8):313-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 71186250 AU - Michna SW TI - Leptospirosis in British cattle. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/analysis MH - Brucellosis, Bovine/epidemiology MH - Cattle MH - Cattle Diseases/*epidemiology/immunology MH - Great Britain MH - Leptospirosis/epidemiology/immunology/*veterinary PT - JOURNAL ARTICLE DA - 710630 DP - 1971 Apr 10 IS - 0042-4900 TA - Vet Rec PG - 384-6 SB - M CY - ENGLAND IP - 15 VI - 88 JC - XBS EM - 7108 PMID- 5103362 CU - 88 SO - Vet Rec 1971 Apr 10;88(15):384-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71200763 AU - De Monte T AU - Iacono S AU - Sabbadini A TI - [Leptospirosis of Rattus norvegicus Berk. in the city of Trieste] LA - Ita MH - Animal MH - English Abstract MH - Female MH - Italy MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - *Rats MH - Rodent Diseases/*epidemiology MH - Seasons PT - JOURNAL ARTICLE DA - 710713 DP - 1971 Apr IS - 0036-7281 TA - Schweiz Arch Tierheilkd PG - 201-7 CY - SWITZERLAND IP - 4 VI - 113 JC - UE5 EM - 7109 PMID- 5577377 CU - 88 TT - Leptospirosi nel Rattus norvegicus Berk. della citta di Trieste. SO - Schweiz Arch Tierheilkd 1971 Apr;113(4):201-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71188584 AU - Palit A AU - Sharma GL TI - Comparison of microscopic agglutination, indirect haemagglutination and complement-fixation tests in rabbit and buffalo-calf hyperimmune sera for detection of leptospiral antibodies. LA - Eng MH - *Agglutination Tests MH - Animal MH - Antibodies/analysis MH - Buffaloes MH - Comparative Study MH - *Complement Fixation Tests MH - Cross Reactions MH - *Hemagglutination Tests MH - Immune Sera MH - Leptospirosis/*diagnosis/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 710706 DP - 1971 Apr IS - 0007-1935 TA - Br Vet J PG - 154-62 CY - ENGLAND IP - 4 VI - 127 JC - B5C EM - 7108 PMID- 5575635 SO - Br Vet J 1971 Apr;127(4):154-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 71286126 AU - Ducroiset B TI - [Apropos of a case of leptospirosis due to L. pomona] LA - Fre MH - Adolescence MH - Human MH - Leptospirosis/*microbiology/prevention & control MH - Male MH - *Occupational Medicine PT - JOURNAL ARTICLE DA - 711110 DP - 1971 Apr-May IS - 0003-9691 TA - Arch Mal Prof PG - 412-3 CY - FRANCE IP - 4 VI - 32 JC - 7T8 EM - 7112 PMID- 5569476 TT - A propos d'un cas de leptospirose a L. pomona. SO - Arch Mal Prof 1971 Apr-May;32(4):412-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71259464 AU - Mogireva LA AU - Matsiuk VM TI - [Fractionation of Sephadex G-100 of leptospira antigen obtained by Fuller's method] LA - Rus MH - *Antigens MH - Antigens, Bacterial/analysis/isolation & purification MH - Chromatography, Gel MH - English Abstract MH - Hemagglutination Tests MH - Leptospira/*immunology MH - Methods PT - JOURNAL ARTICLE DA - 710930 DP - 1971 Apr TA - Zh Mikrobiol Epidemiol Immunobiol PG - 116-20 SB - M CY - USSR IP - 4 VI - 48 JC - Y9O EM - 7111 PMID- 5561297 CU - 90 TT - Fraktsionirovanie na Sefadekse G-100 leptospiroznogo antigena, poluchennogo po metodu Fullera. SO - Zh Mikrobiol Epidemiol Immunobiol 1971 Apr;48(4):116-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 71238297 AU - Fried M AU - Chorvath B TI - Serum lipoprotein hydrolysis by purified lipases. LA - Eng MH - Animal MH - Bile Acids and Salts MH - Calcium Chloride MH - Enzyme Activation MH - Hydrogen-Ion Concentration MH - Hydrolysis MH - Leptospira/enzymology MH - *Lipase MH - Lipoproteins/*blood MH - Pancreas/enzymology MH - Potentiometry MH - Rhizopus/enzymology MH - Sodium Chloride MH - Species Specificity MH - Swine MH - Temperature MH - Triglycerides PT - JOURNAL ARTICLE DA - 710830 DP - 1971 Apr IS - 0024-4201 TA - Lipids PG - 276-8 SB - M CY - UNITED STATES IP - 4 VI - 6 JC - L73 EM - 7110 PMID- 5556343 CU - 90 SO - Lipids 1971 Apr;6(4):276-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72128832 AU - Pavlov FN AU - Khaibrakhmanova RKh AU - Il'in KI AU - Utekaeva FS AU - Negoda KV TI - [Epizootiology of leptospirosis] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Horse Diseases/epidemiology MH - Horses MH - Leptospirosis/epidemiology/*veterinary MH - Mice MH - Mink MH - Rats MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 720511 DP - 1971 Apr IS - 0042-4846 TA - Veterinariia PG - 56-9 CY - USSR VI - 4 JC - XCC EM - 7207 PMID- 5168722 CU - 88 TT - Voprosy epizootologii leptospiroza. SO - Veterinariia 1971 Apr;4:56-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74115358 AU - Shotts EB Jr AU - Andrews CL AU - Sulzer C AU - Greene E TI - Leptospirosis in cottontail and swamp rabbits of the Mississippi Delta. LA - Eng MH - Agglutination Tests MH - Animal MH - Female MH - Kidney/microbiology MH - Leptospira/immunology/isolation & purification MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/immunology/microbiology/pathology/*veterinary MH - Male MH - Mississippi MH - Nephritis/pathology/veterinary MH - *Rabbits PT - JOURNAL ARTICLE DA - 740503 DP - 1971 Apr IS - 0090-3558 TA - J Wildl Dis PG - 115-7 SB - M CY - UNITED STATES IP - 2 VI - 7 JC - KEM EM - 7406 PMID- 5163730 CU - 88 SO - J Wildl Dis 1971 Apr;7(2):115-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 71261770 AU - Fourcade JP TI - [Procedure to follow in non-tuberculous meningitis with clear fluid] LA - Fre MH - Adolescence MH - Adult MH - Child MH - Child, Preschool MH - Human MH - Leptospirosis/complications MH - Meningitis/*diagnosis/drug therapy/etiology MH - Meningitis, Viral/*diagnosis MH - Mycoses/complications MH - Parasitic Diseases/complications MH - Rickettsia Infections/complications MH - Syphilis/complications PT - JOURNAL ARTICLE DA - 711007 DP - 1971 Apr IS - 0021-7867 TA - Bord Med PG - 1277-86 CY - FRANCE IP - 4 VI - 4 JC - APK EM - 7111 PMID- 5109253 CU - 86 TT - Conduite a tenir devant une meningite a liquide clair, non tuberculeuse. SO - Bord Med 1971 Apr;4(4):1277-86 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 71176147 AU - Chorvath B AU - Benzonana G TI - On the titration and some properties of a leptospiral lipase. LA - Eng MH - Animal MH - Bile Acids and Salts MH - Calcium MH - Cattle MH - Emulsions MH - Enzyme Activation MH - Hydrogen-Ion Concentration MH - Hydrolysis MH - Kinetics MH - Leptospira/*enzymology/growth & development MH - *Lipase/analysis/isolation & purification MH - Methods MH - Osmolar Concentration MH - Sodium Chloride MH - Triglycerides PT - JOURNAL ARTICLE DA - 710617 DP - 1971 Mar 16 IS - 0006-3002 TA - Biochim Biophys Acta PG - 277-82 SB - M CY - NETHERLANDS IP - 2 VI - 231 JC - A0W EM - 7108 PMID- 5102972 CU - 90 SO - Biochim Biophys Acta 1971 Mar 16;231(2):277-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 71203344 AU - Prodrom I AU - Popa O TI - [Electrocardiographic aspects of kalemic disorders caused by leptospirosis] LA - Rum MH - Adult MH - Electrocardiography MH - Female MH - Heart/*physiopathology MH - Human MH - Hyperkalemia/*etiology MH - Hypokalemia/*etiology MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications MH - Male MH - Water-Electrolyte Balance PT - JOURNAL ARTICLE DA - 710715 DP - 1971 Mar-Apr IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 149-52 CY - ROMANIA IP - 2 VI - 16 JC - MXQ EM - 7109 PMID- 5578294 TT - Diskaliemii electrocardiografice in leptospiroza. SO - Microbiol Parazitol Epidemiol (Bucur) 1971 Mar-Apr;16(2):149-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 71183165 AU - Weder W TI - [Studies on leptospiral uveitis] LA - Ger MH - Adult MH - English Abstract MH - Eye Diseases/etiology MH - Fundus Oculi MH - Gonioscopy MH - Human MH - Leptospira/*isolation & purification/pathogenicity MH - Macula Lutea MH - Male MH - Photography MH - Uveitis/complications/drug therapy/*microbiology/therapy MH - Visual Fields MH - *Vitreous Body PT - JOURNAL ARTICLE DA - 710624 DP - 1971 Mar IS - 0023-2165 TA - Klin Monatsbl Augenheilkd PG - 330-8 SB - M CY - GERMANY, WEST IP - 3 VI - 158 JC - KWA EM - 7108 PMID- 5573454 TT - Beobachtungen bei Leptospirosenuveitis. SO - Klin Monatsbl Augenheilkd 1971 Mar;158(3):330-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72063115 AU - Maliavin AG AU - Solov'eva VS AU - Shupliko AN AU - Pobegaev VS AU - Glushkov AA TI - [Immunogenic activity of leptospirosis vaccine] LA - Rus MH - Animal MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Leptospirosis/prevention & control/*veterinary MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 720217 DP - 1971 Mar IS - 0042-4846 TA - Veterinariia PG - 56-7 CY - USSR VI - 3 JC - XCC EM - 7204 PMID- 5166679 CU - 85 TT - Immunogennaia aktivnost' protivoleptospiroznoi vaktsiny. SO - Veterinariia 1971 Mar;3:56-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 73236689 AU - Correa MO AU - Hyakutake S AU - Natale V AU - Tiriba A da C AU - Martirani I AU - Galvao PA AU - Albano A AU - Filippi J de AU - Farhat CK AU - Neto VA TI - [Human leptospirosis due to Leptospira andamana] LA - Por MH - Adult MH - Cerebrospinal Fluid/microbiology MH - Child MH - English Abstract MH - Female MH - Human MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/*cerebrospinal fluid MH - Male PT - JOURNAL ARTICLE DA - 731014 DP - 1971 Mar-Apr IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 137-43 CY - BRAZIL IP - 2 VI - 13 JC - S9D EM - 7311 PMID- 5162521 TT - Leptospirose humana por Leptospira andamana. SO - Rev Inst Med Trop Sao Paulo 1971 Mar-Apr;13(2):137-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 72023801 AU - Fresh JW AU - Tsai CC AU - Saroso JS TI - A leptospirosis study in South Sumatra and Bangka Island, Indonesia. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/analysis MH - Disease Outbreaks MH - Hepatitis A/epidemiology/*etiology/immunology MH - Human MH - Indonesia MH - Leptospira/immunology MH - *Leptospirosis/epidemiology/immunology/veterinary MH - Rats MH - Retrospective Studies MH - Rodent Diseases/microbiology MH - Water Microbiology PT - JOURNAL ARTICLE DA - 711228 DP - 1971 Mar IS - 0038-3619 TA - Southeast Asian J Trop Med Public Health PG - 22-4 SB - M CY - THAILAND IP - 1 VI - 2 JC - UVN EM - 7202 PMID- 5112339 CU - 88 SO - Southeast Asian J Trop Med Public Health 1971 Mar;2(1):22-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 71263232 AU - Mailloux M TI - [Canine leptospirosis] LA - Fre MH - Animal MH - Diagnosis, Differential MH - *Dog Diseases MH - Dogs MH - English Abstract MH - Leptospira MH - Leptospira canicola MH - Leptospira interrogans MH - Leptospirosis/*veterinary MH - Morocco MH - Prognosis MH - Serodiagnosis MH - Serotyping MH - Weil's Disease/veterinary PT - JOURNAL ARTICLE DA - 711008 DP - 1971 Mar-Apr IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 201-10 SB - M CY - FRANCE IP - 2 VI - 64 JC - C4G EM - 7111 PMID- 5109302 CU - 86 TT - Leptospiroses canines. SO - Bull Soc Pathol Exot Filiales 1971 Mar-Apr;64(2):201-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 71184525 AU - Kemenes F AU - Szeky A TI - Contribution to the diagnosis of infectious swine abortion. LA - Eng MH - Abortion, Veterinary/*diagnosis/etiology MH - Animal MH - Animals, Newborn MH - Erysipelothrix/*isolation & purification MH - Erysipelothrix Infections/complications MH - Female MH - Fetus/pathology MH - Gestational Age MH - Kidney/pathology MH - Leptospirosis/complications/veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 710626 DP - 1971 Mar TA - Zentralbl Veterinarmed [B] PG - 170-6 CY - GERMANY, WEST IP - 2 VI - 18 JC - Y72 EM - 7108 PMID- 5103325 CU - 89 SO - Zentralbl Veterinarmed [B] 1971 Mar;18(2):170-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 72009007 AU - Nicolescu M AU - Alamita E AU - Borsai L TI - Serotype identification of leptospira strains isolated in Romania. II. Strains belonging to the hebdomadis serogroup. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigen-Antibody Reactions MH - Antigens/analysis MH - Cross Reactions MH - Immune Sera MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/diagnosis MH - Mice PT - JOURNAL ARTICLE DA - 711207 DP - 1971 Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 59-64 CY - ROMANIA IP - 1 VI - 30 JC - 8EM EM - 7201 PMID- 5096862 SO - Arch Roum Pathol Exp Microbiol 1971 Mar;30(1):59-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 72009001 AU - Straton C AU - Straton A AU - Bercovici C AU - Teodorovici G AU - Buzdugan I AU - Vasiliu D AU - Bobu I TI - [Study of a focus of leptospirosis caused by Leptospira grippotyphosa in a sub-Carpathian zone. II. Studies on the natural reservoir among the rodents captured in the focus] LA - Fre MH - Agricultural Workers' Diseases/epidemiology MH - Animal MH - Disease Reservoirs MH - English Abstract MH - Leptospirosis/*epidemiology MH - Rodent Diseases/*epidemiology MH - Romania MH - Seasons PT - JOURNAL ARTICLE DA - 711207 DP - 1971 Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 129-35 CY - ROMANIA IP - 1 VI - 30 JC - 8EM EM - 7201 PMID- 5096858 CU - 88 TT - Etude d'un foyer de leptospirose a Leptospira grippotyphosa dans une zone subkarpatique. II. Recherches sur le reservoir naturel parmiles rongeurs captures dans le foyer. SO - Arch Roum Pathol Exp Microbiol 1971 Mar;30(1):129-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71235597 AU - Mogireva LA AU - Matsiuk VM AU - Bondarenko BN TI - [Serological activity and biochemical characteristics of leptospirous antigen] LA - Ukr MH - Antibody Formation MH - *Antigens/isolation & purification MH - English Abstract MH - Hemagglutination Tests MH - Hemagglutination, Viral MH - *Immune Sera MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 710823 DP - 1971 Mar-Apr IS - 0026-3664 TA - Mikrobiol Zh PG - 189-95 CY - USSR IP - 2 VI - 33 JC - MZ2 EM - 7110 PMID- 5092250 TT - Serolohichna antyvnist' i biokhimichna kharakterystyka antyheniv z leptospir. SO - Mikrobiol Zh 1971 Mar-Apr;33(2):189-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71227258 AU - Horsch F AU - Marwitz H AU - Janetzky B TI - [Reliability, specificity and sources of error of micro-agglutination reactions (MAR) used in the serodiagnosis of leptospirosis] LA - Ger MH - Agglutination Tests/*veterinary MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - English Abstract MH - Leptospirosis/diagnosis/*veterinary MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 710810 DP - 1971 Mar 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 189-94 CY - GERMANY, EAST IP - 5 VI - 26 JC - NGV EM - 7110 PMID- 5088998 CU - 84 TT - Untersuchungen uber Treffsicherheit, Spezifitat und Fehlerquellen der Mikro-Agglutinations-Reaktion (MAR) zur serologischen Diagnostik der Leptospirose. SO - Monatsh Veterinarmed 1971 Mar 1;26(5):189-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 71142649 AU - Kobayashi J TI - [Leptospirosis and Weil's disease] LA - Jpn MH - Leptospirosis MH - Nursing MH - Weil's Disease PT - JOURNAL ARTICLE DA - 710506 DP - 1971 Mar IS - 0386-9830 TA - Kangogaku Zasshi PG - 73-9 SB - N CY - JAPAN IP - 3 VI - 35 JC - KMM EM - 7106 PMID- 4994319 CU - 91 LI - N SO - Kangogaku Zasshi 1971 Mar;35(3):73-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 71211559 AU - Fanelli V TI - [No. 229. Elementary prescription list for therapy of ictero- hemorrhagic leptospirosis] LA - Ita MH - Human MH - Weil's Disease/*drug therapy PT - JOURNAL ARTICLE DA - 710729 DP - 1971 Feb 15 IS - 0009-9074 TA - Clin Ter PG - 287-91 CY - ITALY IP - 3 VI - 56 JC - DKN EM - 7109 PMID- 5581313 TT - N. 229. Ricettario elementare di terapia della leptospirosi ittero- emorragica. SO - Clin Ter 1971 Feb 15;56(3):287-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 71211239 AU - El'chinova EA AU - Zhurba MD TI - [Immunological changes in Brucella-infected animals following vaccine therapy] LA - Rus MH - Animal MH - Antibody Formation MH - Brucella Vaccine MH - Brucellosis/*therapy MH - Cholera Vaccine MH - Dysentery, Bacillary/immunology MH - English Abstract MH - Immune Sera MH - *Immunotherapy MH - Leptospirosis/immunology MH - Phagocytosis MH - Pyrogens/therapeutic use MH - Rabbits PT - JOURNAL ARTICLE DA - 710729 DP - 1971 Feb TA - Zh Mikrobiol Epidemiol Immunobiol PG - 75-80 SB - M CY - USSR IP - 2 VI - 48 JC - Y9O EM - 7109 PMID- 5581224 CU - 89 TT - Immunologicheskie sdvigi u infitsirovannykh brutsellami zhivotnykh posle primeneniia vaktsinoterapii. SO - Zh Mikrobiol Epidemiol Immunobiol 1971 Feb;48(2):75-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72050821 AU - Bolotskii IA AU - Chulovskii IK AU - Arabian AM TI - [Epizootology of leptospirosis] LA - Rus MH - Animal MH - *Artiodactyla MH - Cattle MH - Cattle Diseases/*epidemiology MH - Disease Vectors MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/epidemiology/*veterinary MH - Rodentia MH - Swine MH - Swine Diseases/*epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 720202 DP - 1971 Feb IS - 0042-4846 TA - Veterinariia PG - 65-8 CY - USSR VI - 2 JC - XCC EM - 7203 PMID- 5166288 CU - 88 TT - K epizootologii leptospiroza. SO - Veterinariia 1971 Feb;2:65-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 72050817 AU - Maliavin AG TI - [Improvement of coliparatyphoid and leptospirosis preparations] LA - Rus MH - Animal MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Escherichia coli Infections/prevention & control/*veterinary MH - *Immune Sera MH - Immunization/veterinary MH - Leptospirosis/prevention & control/*veterinary MH - Paratyphoid Fever/prevention & control/*veterinary MH - Swine MH - Swine Diseases/*prevention & control MH - Typhoid-Paratyphoid Vaccines PT - JOURNAL ARTICLE DA - 720202 DP - 1971 Feb IS - 0042-4846 TA - Veterinariia PG - 59-61 CY - USSR VI - 2 JC - XCC EM - 7203 PMID- 5001280 CU - 91 TT - Sovershenstvovanie koliparatifoznykh i leptospiroznykh preparatov. SO - Veterinariia 1971 Feb;2:59-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 71127691 AU - Morahan RJ TI - Further leptospiral isolations in the Sepik district, Territory of Papua and New Guinea. LA - Eng MH - Animal MH - Animals, Domestic MH - Dogs MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Marsupialia MH - New Guinea PT - JOURNAL ARTICLE DA - 710415 DP - 1971 Jan 30 IS - 0025-729X TA - Med J Aust PG - 276-7 SB - M CY - AUSTRALIA IP - 5 VI - 1 JC - M26 EM - 7106 PMID- 5101948 CU - 88 SO - Med J Aust 1971 Jan 30;1(5):276-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71217144 AU - Tsai CC AU - Kundin WD AU - Fresh JW TI - The zoonotic importance of urban rats as a potential reservoir for human leptospirosis. LA - Eng MH - Animal MH - *Disease Reservoirs MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*etiology MH - *Rats MH - Taiwan MH - Urban Population MH - *Zoonoses PT - JOURNAL ARTICLE DA - 710804 DP - 1971 Jan 28 IS - 0371-7682 TA - Taiwan I Hsueh Hui Tsa Chih PG - 1-4 CY - TAIWAN IP - 1 VI - 70 JC - I6V EM - 7109 PMID- 5282558 CU - 88 SO - Taiwan I Hsueh Hui Tsa Chih 1971 Jan 28;70(1):1-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 71105055 AU - Geus A de TI - [Acute leptospirosis in humans in Kenya] LA - Dut MH - Acute Disease MH - Adult MH - Child MH - Diagnosis, Differential MH - Human PT - JOURNAL ARTICLE DA - 710324 DP - 1971 Jan 23 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 178-80 CY - NETHERLANDS IP - 4 VI - 115 JC - NUK EM - 7105 PMID- 5100430 CU - 85 TT - Acute leptospirose bij de mens in Kenia. SO - Ned Tijdschr Geneeskd 1971 Jan 23;115(4):178-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 71105050 AU - Bieger R AU - Graeff J de AU - Veltkamp JJ AU - Furth R van TI - [Icterohemorrhagic leptospirosis (Weil's disease)] LA - Dut MH - Adult MH - Aged MH - Anemia, Hemolytic/etiology MH - Antibiotics/therapeutic use MH - Child MH - Human PT - JOURNAL ARTICLE DA - 710324 DP - 1971 Jan 23 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 146-55 CY - NETHERLANDS IP - 4 VI - 115 JC - NUK EM - 7105 PMID- 5100429 CU - 85 TT - Leptospirosis icterohaemorrhagiae (ziekte van Weil) SO - Ned Tijdschr Geneeskd 1971 Jan 23;115(4):146-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 71089846 AU - Schubert GE AU - Hensel G AU - Vogt W TI - [Acute renal failure in leptospirosis (with a report on the differential diagnosis of leptospirosis sejro and leptospirosis icterohaemorrhagica)] LA - Ger MH - Agglutination Tests MH - Autopsy MH - Diagnosis, Differential MH - English Abstract MH - Human MH - Kidney Failure, Acute/*complications/etiology/pathology MH - Leptospira/enzymology MH - Leptospira interrogans/enzymology MH - Leptospirosis/*complications/pathology MH - Liver/pathology MH - Male MH - Middle Age MH - Pancreatitis/pathology MH - Uremia/complications/diagnosis MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 710311 DP - 1971 Jan 15 IS - 0027-2973 TA - Munch Med Wochenschr PG - 80-6 SB - M CY - GERMANY, WEST IP - 3 VI - 113 JC - MMW EM - 7104 PMID- 5107494 CU - 86 TT - Akutes Nierenversagen bei Leptospirose (zugleich ein Beitrag zur Differentialdiagnose der Leptospirosis sejro und Leptospirosis icterohaemorrhagiae) SO - Munch Med Wochenschr 1971 Jan 15;113(3):80-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 71256839 AU - Agarwal RG AU - Gupta KD AU - Bharadwaj TP TI - Leptospirosis in Bikaner (Rajasthan). A case report. LA - Eng MH - Adult MH - Female MH - Human MH - India MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 710927 DP - 1971 Jan IS - 0004-5772 TA - J Assoc Physicians India PG - 53-4 CY - INDIA IP - 1 VI - 19 JC - HG7 EM - 7111 PMID- 5560027 CU - 88 SO - J Assoc Physicians India 1971 Jan;19(1):53-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 71092053 AU - Juhr NC AU - Obi S TI - [Control of the SPF status of experimental animals. Skin test for excluding leptospira infections] LA - Ger MH - Animal MH - Animals, Laboratory MH - Cats MH - Dogs MH - English Abstract MH - *Germ-Free Life MH - Leptospirosis/*diagnosis MH - Male MH - Rats MH - *Skin Tests PT - JOURNAL ARTICLE DA - 710312 DP - 1971 Jan 1 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 8-11 CY - GERMANY, WEST IP - 1 VI - 84 JC - 9Q8 EM - 7104 PMID- 5540686 CU - 84 TT - Kontrolle des SPF-Status von Versuchstieren . Hauttest zum Ausschluss von Leptospiren-Infektionen. SO - Berl Munch Tierarztl Wochenschr 1971 Jan 1;84(1):8-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 74132859 AU - Babudieri B TI - Proposed standardization of the agglutination-adsorption test for Leptospira. LA - Eng MH - Adsorption MH - *Agglutination Tests MH - Leptospira/*classification MH - Methods MH - Serotyping/standards PT - JOURNAL ARTICLE DA - 740531 DP - 1971 IS - 0042-9686 TA - Bull World Health Organ PG - 795-810 CY - SWITZERLAND IP - 6 VI - 44 JC - C80 EM - 7407 PMID- 5317449 CU - 90 SO - Bull World Health Organ 1971;44(6):795-810 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 72082515 AU - Zollinger HU AU - Colombi A AU - Schiltknecht J TI - New clinical and ultrastructural aspects in leptospirosis icterohaemorrhagica (Weil's disease). A clinical, light- and electron microscopic study. LA - Eng MH - Adult MH - Anuria/pathology MH - Biopsy MH - Capillaries/pathology MH - Collagen MH - Edema/pathology MH - Epithelium/cytology MH - Fibroblasts/cytology MH - Histiocytes MH - Human MH - Kidney/*pathology MH - Leukocytes MH - Liver/pathology MH - Lymphocytes MH - Male MH - Microscopy MH - Microscopy, Electron MH - Necrosis/pathology MH - Nephrosis/pathology MH - Weil's Disease/*diagnosis/pathology PT - JOURNAL ARTICLE DA - 720317 DP - 1971 IS - 0042-6423 TA - Virchows Arch Pathol Anat Physiol Klin Med PG - 336-48 SB - M CY - GERMANY, WEST IP - 4 VI - 354 JC - XCZ EM - 7205 PMID- 5316273 CU - 89 SO - Virchows Arch Pathol Anat Physiol Klin Med 1971;354(4):336-48 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 71137198 AU - Cheah JS AU - Ransome GA TI - Significance of very high erythrocyte sedimentation rates (100 mm or above in one hour) in 360 cases in Singapore. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - *Blood Sedimentation MH - Child MH - Collagen Diseases/blood MH - Female MH - Human MH - Infection/blood MH - Leptospirosis/blood MH - Leukemia, Myelocytic, Acute/blood MH - Liver Abscess, Amebic/blood MH - Male MH - Middle Age MH - Neoplasms/blood MH - Rheumatic Fever/blood MH - Singapore MH - *Tropical Medicine PT - JOURNAL ARTICLE DA - 710430 DP - 1971 Jan IS - 0022-5304 TA - J Trop Med Hyg PG - 28-30 SB - M CY - ENGLAND IP - 1 VI - 74 JC - KAV EM - 7106 PMID- 5278877 CU - 88 SO - J Trop Med Hyg 1971 Jan;74(1):28-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 74028823 AU - Vesenjak-Hirjan J AU - Hrabar A AU - Vince-Ribaric V AU - Borcic B AU - Brudnjak Z TI - An outbreak of hemorrhagic fever with a renal syndrome in the Plitvice Lakes area (preliminary report). LA - Eng MH - Adult MH - Animal MH - Arboviruses/isolation & purification MH - Disease Outbreaks/*epidemiology MH - Disease Reservoirs MH - Epidemiologic Methods MH - Hemagglutination Inhibition Tests MH - Hemorrhagic Fevers, Viral/complications/*epidemiology MH - Human MH - Leptospira/isolation & purification MH - Male MH - Nephrotic Syndrome/*etiology MH - Rodentia MH - Seasons MH - Yugoslavia PT - JOURNAL ARTICLE DA - 740115 DP - 1971 IS - 0015-5683 TA - Folia Parasitol (Praha) PG - 275-9 CY - CZECHOSLOVAKIA IP - 3 VI - 18 JC - F2T EM - 7402 PMID- 5163219 CU - 88 SO - Folia Parasitol (Praha) 1971;18(3):275-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 73251476 AU - Udovicic B TI - [Occurrence of leptospirosis in the SR BH (Social Republic of Bosna and Herzegovina)] LA - Scc MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Infant MH - Infant, Newborn MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Rural Health MH - Seasons MH - Sex Factors MH - Yugoslavia PT - JOURNAL ARTICLE DA - 731112 DP - 1971 Jan-Jun IS - 0025-8083 TA - Med Arh PG - 51-9 CY - YUGOSLAVIA IP - 3 VI - 25 JC - LNY EM - 7312 PMID- 5162735 CU - 88 TT - Kretanje leptospiroza u SR BiH epidermiolo ski institut medicinskog fakultata u Sarajevu. SO - Med Arh 1971 Jan-Jun;25(3):51-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 73132459 AU - Twigg GI AU - Hughes DM AU - McDiarmid A TI - Occurrence of leptospirosis in thoroughbred horses. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies, Bacterial MH - England MH - Horse Diseases/*epidemiology/immunology MH - Horses MH - Leptospira/immunology MH - Leptospirosis/epidemiology/immunology/*veterinary PT - JOURNAL ARTICLE DA - 730502 DP - 1971 Jan IS - 0425-1644 TA - Equine Vet J PG - 52-5 CY - ENGLAND IP - 1 VI - 3 JC - EJ9 EM - 7306 PMID- 5161358 CU - 88 SO - Equine Vet J 1971 Jan;3(1):52-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72129015 AU - Ivanov I AU - Babudieri B TI - Isolation and systematic study of the first Bulgarian strains of saprophytic leptospiras. LA - Eng MH - Bulgaria MH - Culture Media MH - Leptospira/*isolation & purification MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 720512 DP - 1971 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 91-4 SB - M CY - ITALY IP - 1 VI - 7 JC - 5BP EM - 7207 PMID- 5140743 SO - Ann Ist Super Sanita 1971;7(1):91-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72033066 AU - Adamski M AU - Kwiatkowska B TI - [4 simultaneous cases of leptospirosis] LA - Pol MH - Adult MH - English Abstract MH - Human MH - Leptospira canicola/isolation & purification MH - Leptospirosis/*diagnosis MH - Male MH - Water Microbiology MH - Water Supply PT - JOURNAL ARTICLE DA - 720111 DP - 1971 IS - 0033-2100 TA - Przegl Epidemiol PG - 437-9 CY - POLAND IP - 3 VI - 25 JC - Q8T EM - 7202 PMID- 5116812 TT - Cztery przypadki jednoczesnego zachorowania na leptospiroze. SO - Przegl Epidemiol 1971;25(3):437-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 71254018 AU - Mailloux M TI - [Simultaneous cases of leptospirosis in a family in Morocco] LA - Fre MH - Child MH - Child, Preschool MH - English Abstract MH - Female MH - Human MH - Leptospira interrogans/isolation & purification MH - Male MH - Morocco MH - Weil's Disease/epidemiology/*genetics PT - JOURNAL ARTICLE DA - 710922 DP - 1971 Jan-Feb IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 42-5 SB - M CY - FRANCE IP - 1 VI - 64 JC - C4G EM - 7111 PMID- 5109177 CU - 88 TT - Cas simultanes de leptospirose dans une famille au Maroc. SO - Bull Soc Pathol Exot Filiales 1971 Jan-Feb;64(1):42-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 71106431 AU - Corbould A TI - Leptospira hardjo in Tasmania. LA - Eng MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/epidemiology/microbiology PT - JOURNAL ARTICLE DA - 710325 DP - 1971 Jan IS - 0005-0423 TA - Aust Vet J PG - 26 SB - M CY - AUSTRALIA IP - 1 VI - 47 JC - 9IE EM - 7105 PMID- 5100644 CU - 88 SO - Aust Vet J 1971 Jan;47(1):26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 74280512 AU - Starostik L AU - Semotan K AU - Machova J TI - [Detection of Leptospira by means of fluorescent antibodies] LA - Cze MH - Animal MH - Cross Reactions MH - English Abstract MH - *Fluorescent Antibody Technique MH - Guinea Pigs MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Mice MH - Rabbits/immunology PT - JOURNAL ARTICLE DA - 740928 DP - 1971 IS - 0375-8427 TA - Vet Med (Praha) PG - 261-8 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 16 JC - XBP EM - 7411 RO - O:46 RO - C:22 PMID- 5006065 CU - 91 TT - Detekce leptospir pomoci fluorescencnich protilatek EA - A SO - Vet Med (Praha) 1971;16(4):261-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 72134318 AU - Ivanov I TI - Our first saprophytic leptospiral strains antigen analysis. 3d communication. LA - Eng MH - Agglutination Tests MH - *Antigens MH - Antigens, Bacterial MH - Bulgaria MH - Leptospira/classification/*immunology/isolation & purification MH - Serotyping MH - Water Microbiology PT - JOURNAL ARTICLE DA - 720522 DP - 1971 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 255-8 CY - BULGARIA IP - 4 VI - 13 JC - F19 EM - 7207 PMID- 5003944 CU - 91 SO - Folia Med (Plovdiv) 1971;13(4):255-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 72084109 AU - Ivanov I TI - [Arvicola terrestris--Leptospira carrier in the rice fields] LA - Fre MH - Animal MH - Bulgaria MH - Disease Reservoirs MH - English Abstract MH - *Leptospira MH - *Rice MH - *Rodentia PT - JOURNAL ARTICLE DA - 720320 DP - 1971 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 204-8 CY - BULGARIA IP - 3 VI - 13 JC - F19 EM - 7205 PMID- 5002612 CU - 91 TT - Arvicola terrestris--porteur de leptospires dans les rizieres. SO - Folia Med (Plovdiv) 1971;13(3):204-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71188245 AU - Pavlov FN TI - [Mixed leptospirosis and paratyphoid fever infection in pigs] LA - Rus MH - Animal MH - Leptospirosis/*veterinary MH - Paratyphoid Fever/*veterinary MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 710706 DP - 1971 Jan IS - 0042-4846 TA - Veterinariia PG - 53-6 CY - USSR VI - 1 JC - XCC EM - 7108 PMID- 4995831 CU - 91 TT - Smeshannaia infektsiia leptospiroza i paratifa svinei. SO - Veterinariia 1971 Jan;1:53-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 72256173 AU - Kuiumdzhiev I AU - Mikhailova L TI - [The biological nature of the granular structures in cultures of leptospira] LA - Bul MH - Bacteriological Techniques MH - English Abstract MH - Leptospira/*cytology PT - JOURNAL ARTICLE DA - 721003 DP - 1971 TA - Izv Mikrobiol Inst (Sofiia) PG - 135-41 CY - BULGARIA VI - 22 JC - H2B EM - 7212 PMID- 4949111 CU - 90 TT - Vurhu biologichnata sushtnost na granularnite strukturi v kulturi ot leptospiri. SO - Izv Mikrobiol Inst (Sofiia) 1971;22:135-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [14 medline neighbors] UI - 71165687 AU - Chorvath B AU - Benzonana G TI - The positional specificity of leptospiral lipases. LA - Eng MH - Alcohol, Ethyl MH - Animal MH - Bile Acids and Salts MH - Chemistry MH - Chromatography, Thin Layer MH - Culture Media MH - Fatty Acids/biosynthesis MH - Gels MH - Hydrogen-Ion Concentration MH - Hydrolysis MH - Immune Sera MH - Leptospira/*enzymology/growth & development MH - Lipase/isolation & purification/*metabolism MH - Pancreas/enzymology MH - Precipitation MH - Rabbits MH - Saccharomyces MH - Silicon Dioxide MH - Solvents MH - Swine MH - Triglycerides/metabolism PT - JOURNAL ARTICLE DA - 710608 DP - 1971 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 123-5 SB - M CY - CZECHOSLOVAKIA IP - 1 VI - 15 JC - IEV EM - 7107 PMID- 4324305 CU - 93 SO - J Hyg Epidemiol Microbiol Immunol 1971;15(1):123-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [25 medline neighbors] UI - 71158189 AU - Talanti S TI - [Zoonoses] LA - Fin MH - Adenoviridae Infections MH - Animal MH - Arbovirus Infections MH - Botulism MH - Brucellosis, Bovine MH - Cattle MH - Diphyllobothriasis MH - Disease Reservoirs MH - Echinococcosis MH - Fascioliasis MH - Human MH - Leptospirosis MH - Listeria Infections MH - Ornithosis MH - Orthomyxoviridae Infections MH - Pasteurella Infections MH - Rabies MH - Salmonella Infections MH - Salmonella Infections, Animal MH - Staphylococcal Infections MH - Taeniasis MH - Toxoplasmosis, Animal MH - Tuberculosis MH - Tuberculosis, Bovine MH - Tularemia MH - *Zoonoses PT - JOURNAL ARTICLE PT - REVIEW DA - 710530 DP - 1971 IS - 0012-7183 TA - Duodecim PG - 495-510 CY - FINLAND IP - 7 VI - 87 JC - EDD EM - 7107 PMID- 4323998 CU - 93 TT - Zoonoosit. SO - Duodecim 1971;87(7):495-510 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [79 medline neighbors] UI - 71134632 AU - Verin P TI - [Infectious pathology] LA - Fre MH - Borrelia Infections MH - Chlamydia/isolation & purification MH - Chlamydia Infections MH - Eye Diseases/*etiology MH - Human MH - L Forms MH - Leptospirosis MH - Mycoplasma Infections MH - Rickettsia Infections MH - Spirochaeta MH - Trachoma/diagnosis/epidemiology/microbiology/therapy PT - JOURNAL ARTICLE PT - REVIEW DA - 710426 DP - 1971 Jan IS - 0003-973X TA - Arch Ophtalmol Rev Gen Ophtalmol PG - 71-109 SB - M CY - FRANCE IP - 1 VI - 31 JC - BBU EM - 7106 RF - 475 PMID- 4251237 CU - 92 TT - Pathologie infectieuse. SO - Arch Ophtalmol Rev Gen Ophtalmol 1971 Jan;31(1):71-109 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 72023233 AU - Teodorovici G AU - Buzdugan I AU - Vasiliu D AU - Straton A AU - Straton C AU - Mardari A AU - Nastase A AU - Vasiliu A TI - [Study of focus of leptospirosis caused by L. grippotyphosa in a sub- Carpathian zone. I. Clinical, epidemiological and epizootological studies] LA - Fre MH - Adolescence MH - Adult MH - Agricultural Workers' Diseases/*epidemiology MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - *Disease Reservoirs MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Male MH - Rodent Diseases/*epidemiology MH - Romania MH - Seasons PT - JOURNAL ARTICLE DA - 711228 DP - 1970 Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 695-703 CY - ROMANIA IP - 4 VI - 29 JC - 8EM EM - 7202 PMID- 5535380 CU - 88 TT - Etude d'un foyer de leptospirose a L. grippotyphosa dans une zone sous- karpatique. I. Recherches cliniques, epidemiologiques et epizootologiques. SO - Arch Roum Pathol Exp Microbiol 1970 Dec;29(4):695-703 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72023226 AU - Nicolescu M AU - Alamita E AU - Borsai L TI - Serotype identification of Leptospira strains isolated in Romania. I. Strains belonging to the Tarassovi serogroup. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigen-Antibody Reactions MH - Cross Reactions MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/diagnosis/*veterinary MH - Mice MH - Rodent Diseases/*diagnosis MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 711228 DP - 1970 Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 637-41 CY - ROMANIA IP - 4 VI - 29 JC - 8EM EM - 7202 PMID- 5535379 CU - 85 SO - Arch Roum Pathol Exp Microbiol 1970 Dec;29(4):637-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71154927 AU - Karysheva AF AU - Tuzova RV TI - [Serological diagnosis of swine leptospirosis] LA - Rus MH - Animal MH - Leptospirosis/diagnosis/*veterinary MH - Serotyping MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 710525 DP - 1970 Dec IS - 0042-4846 TA - Veterinariia PG - 85-6 CY - USSR VI - 12 JC - XCC EM - 7107 PMID- 5534225 CU - 85 TT - Serologicheskaia diagnostika leptospiroza svinei. SO - Veterinariia 1970 Dec;12:85-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [130 medline neighbors] UI - 71190633 AU - Burger G AU - Fuchs GH TI - Trace elements and reproduction of Leptospirae. LA - Eng MH - Cobalt/*pharmacology MH - Culture Media MH - Leptospira/*growth & development MH - Reproduction MH - Zinc/*pharmacology PT - JOURNAL ARTICLE DA - 710706 DP - 1970 Dec IS - 0021-8847 TA - J Appl Bacteriol PG - 775-8 CY - ENGLAND IP - 4 VI - 33 JC - HDJ EM - 7108 PMID- 5516601 SO - J Appl Bacteriol 1970 Dec;33(4):775-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71092630 AU - Smit AM AU - Wolff JW AU - Rijk-Bohlander HJ de TI - Serotypes in, and clinical notes on, leptospirosis in a plantation area of Sumatra. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Environmental Health MH - Female MH - Hemagglutination Tests MH - Human MH - Indonesia MH - Leptospira/*classification MH - Leptospira canicola/classification MH - Leptospira interrogans/classification MH - Leptospirosis/*epidemiology/*microbiology MH - Male MH - *Serotyping MH - Sex Factors MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 710312 DP - 1970 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 423-30 SB - M CY - NETHERLANDS IP - 4 VI - 22 JC - WGJ EM - 7104 PMID- 5497377 CU - 88 SO - Trop Geogr Med 1970 Dec;22(4):423-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 71056236 AU - Freeman MJ AU - Morter RL AU - Decker MJ TI - Cold hemagglutinin associated with leptospiral hemolytic anemia in the sheep. LA - Eng MH - Anemia, Hemolytic/*immunology MH - Animal MH - Antibodies/*analysis MH - Centrifugation, Density Gradient MH - Cold MH - Hamsters MH - Heat MH - Hemagglutination Tests MH - Hemoglobins/analysis MH - Hemolysis MH - IgG/analysis MH - IgM/analysis MH - Immunoelectrophoresis MH - Leptospirosis/*immunology MH - Mercaptoethanol/pharmacology MH - Sheep MH - Sheep Diseases/*immunology MH - Time Factors PT - JOURNAL ARTICLE DA - 710202 DP - 1970 Dec IS - 0037-9727 TA - Proc Soc Exp Biol Med PG - 887-92 SB - M CY - UNITED STATES IP - 3 VI - 135 JC - PXZ EM - 7103 PMID- 5486728 CU - 90 SO - Proc Soc Exp Biol Med 1970 Dec;135(3):887-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 91082824 AU - Sitprija V AU - Evans H TI - The kidney in human leptospirosis. LA - Eng MH - Adult MH - Aged MH - Case Report MH - Female MH - Human MH - Kidney/pathology MH - Kidney Diseases/etiology/*microbiology/pathology MH - Leptospirosis/*complications/pathology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 910128 DP - 1970 Dec IS - 0002-9343 TA - Am J Med PG - 780-8 SB - A SB - M SB - X CY - UNITED STATES IP - 6 VI - 49 JC - 3JU EM - 9104 PMID- 5006616 NP - X SO - Am J Med 1970 Dec;49(6):780-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71154900 AU - Soloshenko IZ AU - Petrov EM AU - Shorokhov VV AU - Drogun AG AU - Reichuk EA TI - [Epizootiology of leptospirosis] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology/microbiology MH - Horse Diseases/*epidemiology/microbiology MH - Horses MH - Leptospirosis/epidemiology/*veterinary MH - Russia MH - Sheep MH - Sheep Diseases/*epidemiology/microbiology MH - Swine MH - Swine Diseases/*epidemiology/microbiology PT - JOURNAL ARTICLE DA - 710525 DP - 1970 Dec IS - 0042-4846 TA - Veterinariia PG - 41-3 CY - USSR VI - 12 JC - XCC EM - 7107 PMID- 4251593 CU - 92 TT - Voprosy epizootologii leptospiroza. SO - Veterinariia 1970 Dec;12:41-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 71084452 AU - Poh SC AU - Soh CS TI - Lung manifestations in leptospirosis. LA - Eng MH - Adult MH - Cough/etiology MH - Diagnosis, Differential MH - Hemoptysis/etiology MH - Human MH - Leptospirosis/*complications/diagnosis/radiography MH - Lung Diseases/*etiology/radiography MH - Male MH - Tuberculosis, Pulmonary/diagnosis PT - JOURNAL ARTICLE DA - 710304 DP - 1970 Nov IS - 0040-6376 TA - Thorax PG - 751-5 SB - M CY - ENGLAND IP - 6 VI - 25 JC - VQW EM - 7104 PMID- 5494684 SO - Thorax 1970 Nov;25(6):751-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71057498 AU - Sullivan ND AU - Callan DP TI - Isolation of Leptospira hardjo from cows with mastitis. LA - Eng MH - Animal MH - Antibodies/analysis MH - Cattle MH - Cattle Diseases/*microbiology MH - Fever/veterinary MH - Leptospira/*isolation & purification MH - Mastitis, Bovine/*microbiology PT - JOURNAL ARTICLE DA - 710204 DP - 1970 Nov IS - 0005-0423 TA - Aust Vet J PG - 537-9 SB - M CY - AUSTRALIA IP - 11 VI - 46 JC - 9IE EM - 7103 PMID- 5486968 SO - Aust Vet J 1970 Nov;46(11):537-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 70283701 AU - Corrigan JJ Jr AU - Jordan CM TI - Heparin therapy in septicemia with disseminated intravascular coagulation. LA - Eng MH - Afibrinogenemia/complications MH - Blood Coagulation Disorders/*drug therapy MH - Blood Coagulation Factors/analysis MH - Blood Coagulation Tests MH - Child MH - Child, Preschool MH - Disseminated Intravascular Coagulation/drug therapy/etiology MH - Enterobacter/isolation & purification MH - Escherichia coli/isolation & purification MH - Female MH - Fibrinogen/analysis MH - Haemophilus influenzae/isolation & purification MH - Hemorrhage/complications MH - Heparin/*therapeutic use MH - Human MH - Hypotension/complications MH - Infant MH - Infant, Newborn MH - Leptospira/isolation & purification MH - Male MH - Neisseria meningitidis/isolation & purification MH - Prognosis MH - Prothrombin Time MH - Pseudomonas/isolation & purification MH - Septicemia/*complications/microbiology/mortality MH - Shock, Septic/complications/*mortality MH - Staphylococcus/isolation & purification MH - Streptococcus/isolation & purification PT - JOURNAL ARTICLE DA - 701027 DP - 1970 Oct 8 IS - 0028-4793 TA - N Engl J Med PG - 778-82 SB - A SB - M CY - UNITED STATES IP - 15 VI - 283 JC - NOW EM - 7012 PMID- 4989565 CU - 91 SO - N Engl J Med 1970 Oct 8;283(15):778-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71065355 AU - Singh SP TI - A comparative study of serological diagnostic tests of leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Complement Fixation Tests MH - Leptospirosis/diagnosis/*veterinary MH - Sheep MH - Sheep Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 710210 DP - 1970 Oct IS - 0019-6479 TA - Indian Vet J PG - 817-9 CY - INDIA IP - 10 VI - 47 JC - GM9 EM - 7103 PMID- 5530931 CU - 85 SO - Indian Vet J 1970 Oct;47(10):817-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71064384 AU - Matsui H TI - [Studies on indirect hemagglutination test for serodiagnosis of leptospirosis] LA - Jpn MH - Animal MH - Antigens MH - English Abstract MH - Heat MH - *Hemagglutination Tests MH - Human MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis MH - Peptide Hydrolases/pharmacology MH - Rabbits MH - Tannins/pharmacology PT - JOURNAL ARTICLE DA - 710210 DP - 1970 Oct IS - 0021-5082 TA - Nippon Eiseigaku Zasshi PG - 408-14 CY - JAPAN IP - 4 VI - 25 JC - KKN EM - 7103 PMID- 5530884 CU - 85 SO - Nippon Eiseigaku Zasshi 1970 Oct;25(4):408-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71064378 AU - Imamura S AU - Ashizawa Y TI - [Studies on the serological reactions of leptospira. II. Indirect hemagglutination test] LA - Jpn MH - Antigens/isolation & purification MH - Chromatography, Gel MH - English Abstract MH - *Hemagglutination Tests MH - Immune Sera MH - Leptospira interrogans/*immunology MH - Tannins/pharmacology PT - JOURNAL ARTICLE DA - 710210 DP - 1970 Oct IS - 0021-5082 TA - Nippon Eiseigaku Zasshi PG - 360-3 CY - JAPAN IP - 4 VI - 25 JC - KKN EM - 7103 PMID- 5530878 CU - 85 SO - Nippon Eiseigaku Zasshi 1970 Oct;25(4):360-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [26 medline neighbors] UI - 71139492 AU - Yam PA AU - Miller NG AU - White RJ TI - A leptospiral factor producing a cytopathic effect on L cells. LA - Eng MH - Ammonium Compounds/diagnostic use MH - Animal MH - Bacterial Proteins/*analysis MH - *Cytopathogenic Effect, Viral MH - Heat MH - Hemagglutination Tests MH - Hemolysins/analysis MH - Hydrogen-Ion Concentration MH - Injections MH - *L Cells MH - Leptospira/*pathogenicity MH - Muscles/pathology MH - Neutralization Tests MH - Precipitation MH - Protein Denaturation MH - Rabbits MH - Skin/pathology MH - Species Specificity MH - Sulfates/diagnostic use MH - Trypsin MH - *Virulence PT - JOURNAL ARTICLE DA - 710504 DP - 1970 Oct IS - 0022-1899 TA - J Infect Dis PG - 310-7 SB - A SB - M CY - UNITED STATES IP - 4 VI - 122 JC - IH3 EM - 7106 PMID- 5504712 SO - J Infect Dis 1970 Oct;122(4):310-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 71030316 AU - Plesko I AU - Lataste-Dorolle C TI - [Cross immunity in experimental leptospirosis. Reciprocal protective effects effected by Grippotyphosa strains and strains of other serogroups] LA - Fre MH - Animal MH - Antibodies/analysis MH - Cross Reactions MH - English Abstract MH - Guinea Pigs MH - Hamsters MH - *Immunity, Active MH - Leptospira canicola MH - Leptospira interrogans MH - Leptospirosis/*immunology MH - Serotyping MH - Weil's Disease/*immunology PT - JOURNAL ARTICLE DA - 710104 DP - 1970 Oct IS - 0020-2444 TA - Ann Inst Pasteur (Paris) PG - 456-67 SB - M CY - FRANCE IP - 4 VI - 119 JC - 58Y EM - 7102 PMID- 5478266 TT - Immunite croisee en leptospirose experimentale. Effets protecteurs reciproques realises par des souches Grippotyphosa et des souches d'autres serogroupes. SO - Ann Inst Pasteur (Paris) 1970 Oct;119(4):456-67 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70289290 AU - Schnurrenberger PR AU - Hanson LE AU - Martin RJ TI - Leptospirosis: long-term surveillance on an Illinois farm. LA - Eng MH - Agglutination Tests MH - Agriculture MH - Animal MH - Animals, Domestic MH - Cats MH - Cattle MH - Cattle Diseases/*epidemiology/etiology/microbiology MH - Disease Vectors MH - Dogs MH - Human MH - Illinois MH - Leptospira/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/epidemiology/etiology/microbiology/*veterinary MH - Mice MH - Opossums MH - Prospective Studies MH - Raccoons MH - Rats MH - Rodent Diseases/*epidemiology/microbiology MH - Swine MH - Swine Diseases/*epidemiology/etiology/microbiology MH - Water Microbiology PT - JOURNAL ARTICLE DA - 701105 DP - 1970 Oct IS - 0002-9262 TA - Am J Epidemiol PG - 223-39 SB - M CY - UNITED STATES IP - 4 VI - 92 JC - 3H3 EM - 7012 PMID- 5466317 CU - 88 SO - Am J Epidemiol 1970 Oct;92(4):223-39 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 71154991 AU - Kokovin IL AU - Chernukha IuG TI - [Serological classification of leptospirae of the grippotyphosa serogroup--new serological type ratnapura] LA - Rus MH - Animal MH - English Abstract MH - Human MH - Leptospira/*classification MH - Rodentia MH - Russia MH - Serotyping MH - Sri Lanka PT - JOURNAL ARTICLE DA - 710525 DP - 1970 Oct TA - Zh Mikrobiol Epidemiol Immunobiol PG - 102-5 SB - M CY - USSR IP - 10 VI - 47 JC - Y9O EM - 7107 PMID- 4251597 CU - 92 TT - K serologicheskoi klassifikatsii leptospir serogruppy grippotyphosa-- novyi tip ratnapura. SO - Zh Mikrobiol Epidemiol Immunobiol 1970 Oct;47(10):102-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 71206865 AU - Mailloux M TI - [Some epidemiological aspects of leptospirosis in Morocco. Survey on rats. Conditions peculiar to Meknes] LA - Fre MH - Animal MH - *Disease Reservoirs MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology/microbiology MH - Morocco MH - *Rats MH - Rodent Diseases/*epidemiology MH - Serodiagnosis MH - *Water Microbiology MH - Weil's Disease/epidemiology/microbiology PT - JOURNAL ARTICLE DA - 710722 DP - 1970 Sep-Oct IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 547-57 SB - M CY - FRANCE IP - 5 VI - 63 JC - C4G EM - 7109 PMID- 5537747 CU - 88 TT - Quelques aspects epidemiologiques des leptospiroses au Maroc. Enquete sur les rats. Conditions particulieres a Meknes. SO - Bull Soc Pathol Exot Filiales 1970 Sep-Oct;63(5):547-57 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 71091269 TI - [Acute renal failure in leptospirosis. Report of 2 cases] LA - Heb MH - Adult MH - Human MH - Kidney Failure, Acute/*complications MH - Leptospirosis/*complications MH - Male PT - JOURNAL ARTICLE DA - 710312 DP - 1970 Sep 1 IS - 0017-7768 TA - Harefuah PG - 241-2 CY - ISRAEL IP - 5 VI - 79 JC - FZF EM - 7104 PMID- 5496977 NI - A SO - Harefuah 1970 Sep 1;79(5):241-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 71008139 AU - Kmety E TI - Comparative studies of some recently described new leptospiral serotypes. LA - Eng MH - Agglutination Tests MH - Antigens/classification MH - Human MH - Leptospira/*classification/immunology MH - *Serotyping PT - JOURNAL ARTICLE DA - 701202 DP - 1970 Sep IS - 0041-3232 TA - Trop Geogr Med PG - 357-63 SB - M CY - NETHERLANDS IP - 3 VI - 22 JC - WGJ EM - 7101 PMID- 5470902 SO - Trop Geogr Med 1970 Sep;22(3):357-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 72081617 AU - Sagdeeva LG TI - [1 of the causes of nonspecific false positive reactions in syphilis] LA - Rus MH - Animal MH - *Antigens, Heterophile MH - *False Positive Reactions MH - Human MH - Leptospira/*immunology MH - Rabbits MH - *Syphilis Serodiagnosis PT - JOURNAL ARTICLE DA - 720316 DP - 1970 Sep TA - Vestn Dermatol Venerol PG - 59-64 CY - USSR IP - 9 VI - 44 JC - X9U EM - 7205 PMID- 5316246 CU - 89 TT - Ob odnoi iz prichin nespetsificheskikh lozhno-polozhitel'nykh reaktsii na sifilis. SO - Vestn Dermatol Venerol 1970 Sep;44(9):59-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 71228593 AU - Tagi-Zade TA AU - Mardanly AS AU - Akhmedov IB AU - Alekperov FP AU - Gasanov ShN TI - [Leptospirosis in bats in the Azerbaijan SSR] LA - Rus MH - Animal MH - Azerbaijan MH - *Chiroptera MH - English Abstract MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 710811 DP - 1970 Sep TA - Zh Mikrobiol Epidemiol Immunobiol PG - 118-21 SB - M CY - USSR IP - 9 VI - 47 JC - Y9O EM - 7110 PMID- 4253547 CU - 92 TT - Issledovaniia na leptospiroz letuchikh myshei na territorii Azerbaidzhanskoi SSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1970 Sep;47(9):118-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 71238940 AU - Wolff F TI - [Occupational diseases and job-related problems in animal husbandry] LA - Ger MH - Agricultural Workers' Diseases/epidemiology MH - Animal MH - Brucellosis/epidemiology MH - Cattle MH - English Abstract MH - Erysipeloid/epidemiology MH - Female MH - Germany, East MH - Human MH - Leptospirosis/epidemiology MH - Male MH - Occupational Diseases/*epidemiology MH - Ornithosis/epidemiology MH - Tinea/epidemiology MH - Tuberculosis, Bovine/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 710901 DP - 1970 Aug 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 615-21 CY - GERMANY, EAST IP - 16 VI - 25 JC - NGV EM - 7110 PMID- 5534877 CU - 88 TT - Berufskrankheiten und berufsbedingte Erschwernisse in der Tierhaltung. SO - Monatsh Veterinarmed 1970 Aug 15;25(16):615-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71238942 AU - Horsch F AU - Klockmann J AU - Janetzky B AU - Drechsler H AU - Lobnitz P TI - [Leptospirosis in wild animals] LA - Ger MH - Animal MH - Antibodies/analysis MH - Carnivora MH - Deer MH - Disease Reservoirs/*veterinary MH - English Abstract MH - Germany, East MH - Insectivora MH - Leptospirosis/epidemiology/*veterinary MH - Rabbits MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 710901 DP - 1970 Aug 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 634-9 CY - GERMANY, EAST IP - 16 VI - 25 JC - NGV EM - 7110 PMID- 5512055 CU - 88 TT - Untersuchungen von Wildtieren auf Leptospirose. SO - Monatsh Veterinarmed 1970 Aug 15;25(16):634-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 71026653 AU - Stalheim OH AU - Heddleston KL TI - Isolation of Pasteurella multocida from the urine of steers. LA - Eng MH - Animal MH - Blood/microbiology MH - *Cattle MH - Hamsters MH - Kidney/microbiology MH - Leptospirosis/immunology MH - Liver/microbiology MH - Nose/microbiology MH - Pasteurella/*isolation & purification MH - Urine/*microbiology MH - Vaccines PT - JOURNAL ARTICLE DA - 701221 DP - 1970 Aug 1 IS - 0042-4900 TA - Vet Rec PG - 135-6 SB - M CY - ENGLAND IP - 5 VI - 87 JC - XBS EM - 7102 PMID- 5529227 CU - 85 SO - Vet Rec 1970 Aug 1;87(5):135-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71009157 AU - Knott SG AU - Dadswell LP TI - An outbreak of bovine abortions associated with leptospirosis. LA - Eng MH - Abortion, Veterinary/blood/*etiology MH - Agglutination Tests MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/*etiology MH - Disease Outbreaks MH - Female MH - Leptospirosis/complications/*veterinary MH - Pregnancy MH - Seasons PT - JOURNAL ARTICLE DA - 701204 DP - 1970 Aug IS - 0005-0423 TA - Aust Vet J PG - 385-6 SB - M CY - AUSTRALIA IP - 8 VI - 46 JC - 9IE EM - 7101 PMID- 5528506 CU - 85 SO - Aust Vet J 1970 Aug;46(8):385-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71181537 AU - Mailloux M AU - Benkirane N TI - [Epidemiologic aspects of leptospiroses in the region of Meknes] LA - Fre MH - Animal MH - Disease Vectors MH - Human MH - Leptospirosis/*epidemiology MH - Morocco MH - Rats MH - Water Microbiology MH - Weil's Disease/epidemiology MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 710622 DP - 1970 Aug IS - 0300-9114 TA - Voen Med Zh PG - 442-4 CY - USSR VI - 8 JC - XGS EM - 7108 PMID- 5515340 CU - 88 TT - Aspects epidemiologiques des leptospiroses dans la region de Meknes. SO - Voen Med Zh 1970 Aug;8:442-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 71012629 AU - Broser F AU - Worlein B TI - [2 cases of cerebellitis leptospirosa] LA - Ger MH - Adult MH - Agglutination Tests MH - Cerebellar Diseases/*diagnosis MH - Cerebellum MH - Diagnosis, Differential MH - Electromyography MH - Female MH - Follow-Up Studies MH - Haloperidol/therapeutic use MH - Human MH - Leptospirosis/cerebrospinal fluid/*diagnosis MH - Male MH - Meningitis/diagnosis MH - Middle Age PT - JOURNAL ARTICLE DA - 701209 DP - 1970 Aug IS - 0028-2804 TA - Nervenarzt PG - 407-11 SB - M CY - GERMANY, WEST IP - 8 VI - 41 JC - NWS EM - 7101 PMID- 5472981 TT - Zwei Falle von Cerebellitis Leptospirosa. SO - Nervenarzt 1970 Aug;41(8):407-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 71008318 AU - Lim P TI - Hyperosmolality in leptospirosis. LA - Eng MH - Coma/*etiology MH - Human MH - Hyperglycemia/etiology MH - Kidney Diseases/etiology MH - Leptospirosis/*complications MH - Liver Diseases/etiology MH - Osmolar Concentration MH - Peritoneal Dialysis/adverse effects PT - JOURNAL ARTICLE DA - 701203 DP - 1970 Aug IS - 0571-9283 TA - Australas Ann Med PG - 263-5 SB - M CY - AUSTRALIA IP - 3 VI - 19 JC - 9IJ EM - 7101 PMID- 5470977 SO - Australas Ann Med 1970 Aug;19(3):263-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 70261746 AU - Reilly JR AU - Hanson LE AU - Ferris DH TI - Experimentally induced predator chain transmission of Leptospira grippotyphosa from rodents to wild marsupialia and carnivora. LA - Eng MH - Animal MH - Animal Feed MH - *Carnivora MH - *Disease Reservoirs MH - *Disease Vectors MH - *Foxes MH - Leptospirosis/immunology/*veterinary MH - Mice MH - *Opossums MH - *Raccoons MH - Rodent Diseases/*etiology/immunology MH - Seasons PT - JOURNAL ARTICLE DA - 701002 DP - 1970 Aug IS - 0002-9645 TA - Am J Vet Res PG - 1443-8 SB - M CY - UNITED STATES IP - 8 VI - 31 JC - 40C EM - 7011 PMID- 5449900 SO - Am J Vet Res 1970 Aug;31(8):1443-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71029271 AU - Harkness AC AU - Smith BL AU - Fowler GF TI - An isolation of Leptospira serotype pomona from domestic cat. LA - Eng MH - Animal MH - Cat Diseases/*microbiology MH - Cats MH - Leptospira/*isolation & purification PT - JOURNAL ARTICLE DA - 701228 DP - 1970 Aug IS - 0048-0169 TA - N Z Vet J PG - 175-6 CY - NEW ZEALAND IP - 8 VI - 18 JC - OBZ EM - 7102 PMID- 5273623 CU - 88 SO - N Z Vet J 1970 Aug;18(8):175-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71175795 AU - Batkov IuV AU - Sokolov EN TI - [Epizootiology of animal leptispirosis] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Leptospirosis/*veterinary MH - Swine MH - Swine Diseases/*epidemiology MH - Turkmenistan PT - JOURNAL ARTICLE DA - 710615 DP - 1970 Aug IS - 0042-4846 TA - Veterinariia PG - 53 CY - USSR VI - 8 JC - XCC EM - 7108 PMID- 4252060 CU - 92 TT - Ob epizootiologii leptospiroza zhivotnykh. SO - Veterinariia 1970 Aug;8:53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70266179 AU - Oszczak A AU - Kucharska-Golba K AU - Nenycz-Grabiec Z TI - [Meningeal reactions in leptospirosis] LA - Pol MH - Adolescence MH - Adult MH - Aged MH - English Abstract MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*cerebrospinal fluid MH - Male MH - Middle Age MH - Poland MH - Seasons MH - Weil's Disease/cerebrospinal fluid PT - JOURNAL ARTICLE DA - 701006 DP - 1970 Jul 27 IS - 0032-3756 TA - Pol Tyg Lek PG - 1130-2 CY - POLAND IP - 30 VI - 25 JC - PBY EM - 7011 PMID- 5451498 TT - Odczyny oponowe w leptospirozach. SO - Pol Tyg Lek 1970 Jul 27;25(30):1130-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70215915 AU - Thomson W TI - Leptospirosis--an occupational hazard. LA - Eng MH - Animal MH - Animal Diseases MH - Human MH - *Leptospirosis/veterinary MH - Male MH - Middle Age MH - *Occupational Diseases PT - JOURNAL ARTICLE DA - 700810 DP - 1970 Jul 2 IS - 0029-6589 TA - Nurs Times PG - 847-8 CY - ENGLAND IP - 27 VI - 66 JC - O9U EM - 7009 PMID- 5463744 CU - 85 SO - Nurs Times 1970 Jul 2;66(27):847-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 72192724 AU - Thrower WR TI - Agriculture and the public health. The Milroy lectures, 1970. LA - Eng MH - Agricultural Workers' Diseases MH - *Agriculture MH - Animal MH - Brucellosis, Bovine MH - Campylobacter fetus MH - Cattle MH - Cattle Diseases MH - Dairying MH - Dietary Proteins MH - Fertilizers MH - Food Inspection MH - Food Supply MH - Horses/immunology MH - Leptospirosis/veterinary MH - Mastitis, Bovine MH - Parasitic Diseases/veterinary MH - Poultry Diseases MH - *Public Health MH - Salmonella Infections, Animal MH - Scrapie MH - Sewage MH - Sheep MH - Toxoplasmosis, Animal MH - Tuberculosis, Bovine MH - Vibrio Infections/veterinary MH - Zoonoses PT - JOURNAL ARTICLE DA - 720801 DP - 1970 Jul IS - 0035-8819 TA - J R Coll Physicians Lond PG - 277-304 SB - M CY - ENGLAND IP - 4 VI - 4 JC - JVB EM - 7209 PMID- 5535790 CU - 85 SO - J R Coll Physicians Lond 1970 Jul;4(4):277-304 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71212958 AU - Drogun AG AU - Shorokhov VV TI - [Pathomorphological changes during experimental leptospirosis in young pigs] LA - Rus MH - Animal MH - Kidney/*pathology MH - Leptospirosis/pathology/*veterinary MH - Liver/*pathology MH - Swine MH - Swine Diseases/*pathology PT - JOURNAL ARTICLE DA - 710729 DP - 1970 Jul IS - 0042-4846 TA - Veterinariia PG - 61-2 CY - USSR VI - 7 JC - XCC EM - 7109 PMID- 5518286 TT - Patologomorfologicheskie izmeneniia pri eksperimental'nom leptospiroze prositat. SO - Veterinariia 1970 Jul;7:61-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71132402 AU - Mailloux M AU - Benkirane N TI - [Epidemiologic aspects of leptospiroses in the region of Meknes] LA - Fre MH - Animal MH - Disease Vectors MH - Human MH - Leptospirosis/*epidemiology MH - Morocco MH - Rats MH - Water Microbiology MH - Weil's Disease/epidemiology MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 710422 DP - 1970 Jul IS - 0025-388X TA - Maroc Med PG - 442-4 CY - MOROCCO VI - 537 JC - LI6 EM - 7106 PMID- 5503093 CU - 88 TT - Aspects epidemiologiques des leptospiroses dans la region de Meknes. SO - Maroc Med 1970 Jul;537:442-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71130731 AU - Perduca M TI - [Serodiagnosis of leptospirosis. Comparative study of the Martin and Petit test and macroscopic agglutination on slides] LA - Ita MH - Animal MH - Antibodies/*analysis MH - Antibody Formation MH - Antigens MH - Comparative Study MH - Dogs MH - English Abstract MH - Hemagglutination Tests MH - Human MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis/immunology MH - Methods MH - *Serodiagnosis MH - Swine PT - JOURNAL ARTICLE DA - 710420 DP - 1970 Jul-Aug IS - 0017-0267 TA - G Batteriol Virol Immunol PG - 239-47 SB - M CY - ITALY IP - 7 VI - 63 JC - FA5 EM - 7106 PMID- 5502691 CU - 90 TT - La sierodiagnosi delle leptospirosi. Ricerche comparative la prova di Martin e Petit e l'agglutinazione macroscopica su vetrino. SO - G Batteriol Virol Immunol 1970 Jul-Aug;63(7):239-47 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71028511 AU - Correa MO AU - Natale V AU - Sadatsune T AU - Fleury GC TI - [Practical value and use of Patoc I Leptospira semaranga in the diagnosis of human leptospirosis] LA - Por MH - Agglutination Tests MH - Antigens MH - English Abstract MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/immunology PT - JOURNAL ARTICLE DA - 701223 DP - 1970 Jul-Aug IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 284-7 CY - BRAZIL IP - 4 VI - 12 JC - S9D EM - 7102 PMID- 5477537 TT - Valor pratico do uso da Leptospira sem aranga Patoc I no diagnostico das leptospiroses humans. SO - Rev Inst Med Trop Sao Paulo 1970 Jul-Aug;12(4):284-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 70267641 AU - McKiel JA AU - Rappay DE AU - Cousineau JG AU - Hall RR AU - McKenna HE TI - Domestic rats as carriers of leptospires and salmonellae in Eastern Canada. LA - Eng MH - Animal MH - Canada MH - *Disease Vectors MH - Leptospira/*isolation & purification MH - *Leptospirosis MH - *Rats MH - Salmonella/*isolation & purification PT - JOURNAL ARTICLE DA - 701007 DP - 1970 Jul-Aug IS - 0008-4263 TA - Can J Public Health PG - 336-40 CY - CANADA IP - 4 VI - 61 JC - CK6 EM - 7011 PMID- 5465556 CU - 85 SO - Can J Public Health 1970 Jul-Aug;61(4):336-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70256789 AU - Berlowski J TI - [Cases of leptospirosis in the Tarnobrzeg district] LA - Pol MH - Adult MH - Case Report MH - Chloramphenicol/therapeutic use MH - Human MH - Leptospirosis/drug therapy/*epidemiology MH - Male MH - Middle Age MH - Poland PT - JOURNAL ARTICLE DA - 700923 DP - 1970 Jul 1 IS - 0043-5147 TA - Wiad Lek PG - 1131-3 CY - POLAND IP - 13 VI - 23 JC - XOA EM - 7011 PMID- 5448468 CU - 88 TT - Przypadki zachorowania na leptospiroze w powiecie Tarnobrzeskim. SO - Wiad Lek 1970 Jul 1;23(13):1131-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 71238302 AU - Heneberg D AU - Heneberg N AU - Sebek Z TI - [Experiences in the study of natural foci of Zoonoses in Yugoslavia] LA - SCR MH - Animal MH - Brucellosis/*veterinary MH - *Disease Reservoirs MH - *Disease Vectors MH - English Abstract MH - Insectivora MH - Leptospirosis/*veterinary MH - Listeria Infections/*veterinary MH - Mice MH - Rabbits MH - Rats MH - Rodentia MH - Yugoslavia MH - Zoonoses PT - JOURNAL ARTICLE DA - 710830 DP - 1970 Jul IS - 0025-8091 TA - Med Glas PG - 297-305 CY - YUGOSLAVIA IP - 7 VI - 24 JC - LZI EM - 7110 PMID- 5207410 CU - 87 TT - Neka iskustva ispitivanja prirodnih zarista zoonoza u SFRJ. SO - Med Glas 1970 Jul;24(7):297-305 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 71041726 AU - Kovbasko MA TI - [Water fever] LA - Rus MH - Leptospirosis MH - Nursing PT - JOURNAL ARTICLE DA - 710115 DP - 1970 Jul TA - Feldsher Akush PG - 5-8 SB - N CY - USSR IP - 7 VI - 35 JC - EVA EM - 7102 PMID- 5202979 CU - 89 LI - N TT - Vodnaia likhoradka. SO - Feldsher Akush 1970 Jul;35(7):5-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [6 medline neighbors] UI - 70237686 AU - Clapper WE AU - Boecker BB AU - Sanchez A AU - Levy J TI - Anamnestic response to Leptospira canicola and infectious canine hepatitis antigens in beagles exposed to 90Sr by inhalation or intravenous injection. LA - Eng MH - Adenoviruses, Canine/*immunology MH - Aerosols MH - Animal MH - Antibody Formation/*radiation effects MH - Antigen-Antibody Reactions/*radiation effects MH - Complement Fixation Tests MH - Dogs MH - Injections, Intravenous MH - Leptospira canicola/*immunology MH - *Radiation Effects MH - Radiometry MH - Strontium Isotopes/*administration & dosage MH - Time Factors PT - JOURNAL ARTICLE DA - 700906 DP - 1970 Jul IS - 0033-7587 TA - Radiat Res PG - 112-30 SB - M CY - UNITED STATES IP - 1 VI - 43 JC - QMP EM - 7010 PMID- 4317124 CU - 93 SO - Radiat Res 1970 Jul;43(1):112-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71212957 AU - Shatrov AP AU - Kirpichev AF TI - [Epizootiology of leptospirosis] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Female MH - Foxes MH - Horse Diseases/epidemiology MH - Horses MH - Kazakhstan MH - Leptospirosis/epidemiology/*veterinary MH - Mink MH - Seasons MH - Serotyping MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 710729 DP - 1970 Jul IS - 0042-4846 TA - Veterinariia PG - 60-1 CY - USSR VI - 7 JC - XCC EM - 7109 PMID- 4253166 CU - 92 TT - K epizootologii leptospiroza. SO - Veterinariia 1970 Jul;7:60-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 71043319 AU - Bezumnova FI TI - [Epidemiology of anicteric leptospirosis in the Astrakhan region] LA - Rus MH - Adolescence MH - Adult MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Child MH - Child, Preschool MH - Disease Reservoirs MH - Disease Vectors MH - English Abstract MH - Female MH - Human MH - Leptospirosis/*epidemiology/prevention & control/veterinary MH - Male MH - Middle Age MH - Rodentia MH - Russia MH - Swine MH - Swine Diseases/*epidemiology MH - Water Microbiology PT - JOURNAL ARTICLE DA - 710115 DP - 1970 Jul TA - Zh Mikrobiol Epidemiol Immunobiol PG - 36-9 SB - M CY - USSR IP - 7 VI - 47 JC - Y9O EM - 7102 PMID- 4249472 CU - 92 TT - Epidemiologiia bezzheltshnogo leptospiroza v Astrakhanskoi oblasti. SO - Zh Mikrobiol Epidemiol Immunobiol 1970 Jul;47(7):36-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 71204922 AU - Farina R AU - Andreani E TI - [Leptospirosis of wild animals in Italy] LA - Ita MH - Animal MH - *Chiroptera MH - *Foxes MH - Hamsters MH - *Insectivora MH - Leptospirosis/*veterinary MH - *Mammals MH - Mice MH - Rats MH - Rodent Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 710720 DP - 1970 Jun 30 IS - 0004-0479 TA - Arch Vet Ital PG - 127-41 CY - ITALY IP - 2 VI - 21 JC - 8L2 EM - 7109 PMID- 5517482 CU - 88 TT - Leptospirosi degli animali selvatici in Italia. SO - Arch Vet Ital 1970 Jun 30;21(2):127-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71061941 AU - Wieligda-Czerepak R TI - [Leptospirotic meningitis] LA - Pol MH - Adolescence MH - Age Factors MH - Animal MH - Child MH - Human MH - *Leptospirosis MH - Male MH - Meningitis/*etiology MH - Poland MH - *Zoonoses PT - JOURNAL ARTICLE DA - 710209 DP - 1970 Jun IS - 0031-3939 TA - Pediatr Pol PG - 709-11 CY - POLAND IP - 6 VI - 45 JC - OW2 EM - 7103 PMID- 5530743 CU - 85 TT - Meningitis leptospirotica. SO - Pediatr Pol 1970 Jun;45(6):709-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 71001670 AU - Berner DL AU - Hammond EG TI - Specificity of lipase from several seeds and Leptospira pomona. LA - Eng MH - Cereals MH - Corn MH - Hydrogen-Ion Concentration MH - Leptospira/*enzymology MH - Linoleic Acids MH - Lipase/*metabolism MH - Oils MH - Plants MH - Seeds/*enzymology MH - Soybeans MH - Stearic Acids PT - JOURNAL ARTICLE DA - 701120 DP - 1970 Jun IS - 0024-4201 TA - Lipids PG - 572-3 SB - M CY - UNITED STATES IP - 6 VI - 5 JC - L73 EM - 7101 PMID- 5528249 CU - 85 SO - Lipids 1970 Jun;5(6):572-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 71083126 AU - Silva K de AU - Jayaweera BA TI - Leptospiral problems in pregnancy. LA - Eng MH - Abortion/etiology MH - Adult MH - Cross Infection MH - Female MH - Human MH - *Leptospirosis/complications/diagnosis/etiology MH - Pregnancy MH - *Pregnancy Complications, Infectious/diagnosis/etiology PT - JOURNAL ARTICLE DA - 710304 DP - 1970 Jun IS - 0009-0875 TA - Ceylon Med J PG - 96-103 CY - SRI LANKA IP - 2 VI - 15 JC - CY9 EM - 7104 PMID- 5494247 SO - Ceylon Med J 1970 Jun;15(2):96-103 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70256179 AU - Burger G AU - Fuchs GH TI - Trace elements and reproduction of leptospirae. LA - Eng MH - Cadmium/pharmacology MH - Cobalt/pharmacology MH - Copper/pharmacology MH - Culture Media MH - Leptospira/*growth & development MH - Trace Elements/*pharmacology MH - Zinc/pharmacology PT - JOURNAL ARTICLE DA - 700923 DP - 1970 Jun IS - 0021-8847 TA - J Appl Bacteriol PG - 317-20 CY - ENGLAND IP - 2 VI - 33 JC - HDJ EM - 7011 PMID- 5448244 SO - J Appl Bacteriol 1970 Jun;33(2):317-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 70237822 AU - Petelin N AU - Cinco M AU - Magliocchetti-Lombi P TI - Comparative diagnostic significance of some Water-Leptospirae for human Leptospirosis. LA - Eng MH - Agglutination Tests MH - Antigen-Antibody Reactions MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis MH - Methods MH - Serodiagnosis MH - Serotyping PT - JOURNAL ARTICLE DA - 700906 DP - 1970 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 245-9 SB - M CY - NETHERLANDS IP - 2 VI - 22 JC - WGJ EM - 7010 PMID- 5429918 CU - 90 SO - Trop Geogr Med 1970 Jun;22(2):245-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70237821 AU - Cinco M AU - Petelin N TI - Serogroups and serotypes in Water-Leptospira strains. LA - Eng MH - Absorption MH - Agglutination Tests MH - Antigen-Antibody Reactions MH - Italy MH - Leptospira/*classification/isolation & purification MH - Methods MH - Sampling Studies MH - *Serotyping MH - Water Microbiology PT - JOURNAL ARTICLE DA - 700906 DP - 1970 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 237-44 SB - M CY - NETHERLANDS IP - 2 VI - 22 JC - WGJ EM - 7010 PMID- 5429917 CU - 90 SO - Trop Geogr Med 1970 Jun;22(2):237-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 70237297 AU - Chorvath B AU - Fried M TI - Partial purification of an extracellular leptospiral lipase. LA - Eng MH - Alcohol, Ethyl MH - Chromatography MH - Chromatography, Gel MH - Freeze Drying MH - Leptospira/*enzymology MH - Lipase/*isolation & purification MH - Methods MH - Molecular Weight MH - Precipitation MH - Ultracentrifugation PT - JOURNAL ARTICLE DA - 700906 DP - 1970 Jun IS - 0021-9193 TA - J Bacteriol PG - 879-80 SB - M CY - UNITED STATES IP - 3 VI - 102 JC - HH3 EM - 7010 PMID- 5429728 CU - 90 SO - J Bacteriol 1970 Jun;102(3):879-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [168 medline neighbors] UI - 70229029 AU - Bobrowski H TI - [On sporadic cases of leptospirosis in the light of the present state of communicable diseases in Poland] LA - Pol MH - Adult MH - Communicable Diseases/epidemiology MH - Diagnosis, Differential MH - English Abstract MH - Enterovirus Infections/diagnosis MH - Hepatitis A/diagnosis MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - Poland PT - JOURNAL ARTICLE DA - 700825 DP - 1970 Jun IS - 0043-5147 TA - Wiad Lek PG - 933-5 CY - POLAND IP - 11 VI - 23 JC - XOA EM - 7010 PMID- 5426817 CU - 88 TT - W sprawie sporadycznych przypadkow leptospiroz na tle obecnej sytuacji epidemiologicznej w chorobach zakaznych na terenie polski. SO - Wiad Lek 1970 Jun;23(11):933-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 70239909 AU - Taylor PL AU - Hanson LE AU - Simon J TI - Serologic, pathologic, and immunologic features of experimentally induced leptospiral nephritis in dogs. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/analysis MH - Blood/microbiology MH - Blood Cell Count MH - Dog Diseases/immunology/microbiology/*pathology MH - Dogs MH - Fluorescent Antibody Technique MH - Kidney/pathology MH - Leptospira canicola/immunology/isolation & purification MH - Leptospirosis/*veterinary MH - Nephritis/immunology/microbiology/pathology/*veterinary MH - Specific Gravity MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 700909 DP - 1970 Jun IS - 0002-9645 TA - Am J Vet Res PG - 1033-49 SB - M CY - UNITED STATES IP - 6 VI - 31 JC - 40C EM - 7010 PMID- 4914351 CU - 90 SO - Am J Vet Res 1970 Jun;31(6):1033-49 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [5 medline neighbors] UI - 70263303 AU - Potkay S TI - Diseases of the opossum (Didelphis marsupialis): a review. LA - Eng MH - Animal MH - Animal Diseases/*epidemiology MH - Animals, Laboratory MH - Borrelia Infections/epidemiology/veterinary MH - Ectoparasitic Infestations/epidemiology/veterinary MH - Encephalomyelitis, Equine/epidemiology/veterinary MH - Helminthiasis/epidemiology/veterinary MH - Herpesviridae Infections/veterinary MH - Leptospirosis/epidemiology/veterinary MH - Mycobacterium Infections/epidemiology/veterinary MH - Mycoses/epidemiology/veterinary MH - *Opossums MH - Pasteurella Infections/epidemiology/veterinary MH - Protozoan Infections/epidemiology/veterinary MH - Rabies/epidemiology MH - Rickettsia Infections/epidemiology/veterinary MH - Salmonella Infections/epidemiology/veterinary MH - Streptococcal Infections/veterinary PT - JOURNAL ARTICLE PT - REVIEW DA - 701005 DP - 1970 Jun IS - 0094-5331 TA - Lab Anim Care PG - 502-11 SB - M CY - UNITED STATES IP - 3 VI - 20 JC - BDU EM - 7011 RF - 143 PMID- 4317886 CU - 93 SO - Lab Anim Care 1970 Jun;20(3):502-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 71001698 AU - Tan DS TI - Leptospirosis in rural West Malaysia. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Female MH - Human MH - Infant MH - Leptospirosis/*epidemiology/immunology MH - Malaysia MH - Male MH - Middle Age MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 701120 DP - 1970 Jun IS - 0025-7303 TA - Med J Malaya PG - 261-6 CY - MALAYSIA IP - 4 VI - 24 JC - BDM EM - 7101 PMID- 4248346 CU - 92 SO - Med J Malaya 1970 Jun;24(4):261-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 70276861 AU - White DS AU - O'Byrne E AU - O'Loughlin J TI - Serology: Quo vadis? LA - Eng MH - Abortion, Veterinary/*diagnosis/microbiology MH - Agglutination Tests MH - Animal MH - Brucellosis, Bovine/diagnosis MH - Cattle MH - Cattle Diseases/*diagnosis MH - Complement Fixation Tests MH - Coombs' Test MH - Female MH - Hemagglutination Tests MH - Leptospira/isolation & purification MH - Neutralization Tests MH - Pregnancy MH - Q Fever/diagnosis MH - *Serodiagnosis PT - JOURNAL ARTICLE DA - 701013 DP - 1970 May 30 IS - 0042-4900 TA - Vet Rec PG - 658-9 SB - M CY - ENGLAND IP - 22 VI - 86 JC - XBS EM - 7012 PMID- 5465753 CU - 85 SO - Vet Rec 1970 May 30;86(22):658-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71014338 AU - Lindenbaum I AU - Eylan E TI - Human infections with Leptospira Ballum in Israel. LA - Eng MH - Adult MH - Agglutination Tests MH - Animal MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*diagnosis MH - Male MH - Middle Age MH - Rats PT - JOURNAL ARTICLE DA - 701210 DP - 1970 May-Jun IS - 0021-2180 TA - Isr J Med Sci PG - 403-7 SB - M CY - ISRAEL IP - 3 VI - 6 JC - GY0 EM - 7101 PMID- 5528843 CU - 85 SO - Isr J Med Sci 1970 May-Jun;6(3):403-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 71014339 AU - Shenberg E AU - Friedlander A AU - Torten M AU - Ben-Efraim S TI - Leptospiral agglutinating factor in turtles. Further studies on fractionated sera. LA - Eng MH - Animal MH - Chromatography, DEAE-Cellulose MH - Hemagglutination Tests MH - Immunoelectrophoresis MH - Leptospirosis/*immunology MH - Mercaptoethanol MH - Turtles/*immunology MH - Ultracentrifugation PT - JOURNAL ARTICLE DA - 701210 DP - 1970 May-Jun IS - 0021-2180 TA - Isr J Med Sci PG - 408-12 SB - M CY - ISRAEL IP - 3 VI - 6 JC - GY0 EM - 7101 PMID- 5473868 SO - Isr J Med Sci 1970 May-Jun;6(3):408-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [194 medline neighbors] UI - 71014337 AU - Sapiro-Hirsch R AU - Hirsch W TI - First isolation of Leptospira Icterohaemorrhagiae from man in Israel. With Remarks on the paradoxical reaction in the serodiagnosis of leptospirosis. LA - Eng MH - Human MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/blood/diagnosis/urine MH - Male PT - JOURNAL ARTICLE DA - 701210 DP - 1970 May-Jun IS - 0021-2180 TA - Isr J Med Sci PG - 399-402 SB - M CY - ISRAEL IP - 3 VI - 6 JC - GY0 EM - 7101 PMID- 5473867 SO - Isr J Med Sci 1970 May-Jun;6(3):399-402 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 70208316 AU - Benoist F AU - Lataste-Dorolle C TI - [Preliminary research on the vaccination of sewage workers against occupational leptospirosis] LA - Fre MH - Animal MH - English Abstract MH - Human MH - Leptospira interrogans/immunology MH - Leptospirosis/epidemiology/immunology/*prevention & control MH - Male MH - Occupational Diseases/immunology/*prevention & control MH - Paris MH - Rats MH - Serodiagnosis MH - Sewage MH - *Vaccination PT - JOURNAL ARTICLE DA - 700805 DP - 1970 May IS - 0003-410X TA - Ann Med Interne (Paris) PG - 489-96 SB - M CY - FRANCE IP - 5 VI - 121 JC - 5FZ EM - 7009 PMID- 5463386 CU - 88 TT - Recherches preliminaires en vue de la vaccination contre la leptospirose professionnelle des egoutiers. SO - Ann Med Interne (Paris) 1970 May;121(5):489-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 70282014 AU - Kiktenko VS AU - Bakulina NA AU - Troshin KA AU - Kovtunenko LP TI - [The effect of leptospirae on different tissue cultures] LA - Rus MH - Animal MH - Biological Products MH - Carcinoma MH - Chick Embryo MH - English Abstract MH - Fibroblasts MH - Human MH - In Vitro MH - L Cells MH - Laryngeal Neoplasms MH - Leptospira/*pathogenicity MH - Leptospira canicola/pathogenicity MH - Leptospira interrogans/pathogenicity MH - *Tissue Culture PT - JOURNAL ARTICLE DA - 701023 DP - 1970 May TA - Zh Mikrobiol Epidemiol Immunobiol PG - 48-52 SB - M CY - USSR IP - 5 VI - 47 JC - Y9O EM - 7012 PMID- 5455482 CU - 89 TT - Izuchenie vliianiia leptospir na razlichnye kul'tury taknei. SO - Zh Mikrobiol Epidemiol Immunobiol 1970 May;47(5):48-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70191285 AU - Barrett-Connor E AU - Child CM AU - Carter MJ TI - Renal failure in leptospirosis. LA - Eng MH - Human MH - Kidney Failure, Acute/complications/therapy MH - Kidney Function Tests MH - Kidney Tubules MH - Leptospirosis/*complications/diagnosis/therapy MH - Liver Function Tests MH - Male MH - Middle Age MH - Necrosis MH - Peritoneal Dialysis PT - JOURNAL ARTICLE DA - 700709 DP - 1970 May IS - 0038-4348 TA - South Med J PG - 580-3 SB - M CY - UNITED STATES IP - 5 VI - 63 JC - UVH EM - 7008 PMID- 5446827 SO - South Med J 1970 May;63(5):580-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70189782 AU - Baker MF AU - Baker HJ TI - Pathogenic Leptospira in Malaysian surface waters. I. A method of survey for Leptospira in natural waters and soils. LA - Eng MH - Animal MH - Hamsters MH - Leptospira/*pathogenicity MH - Malaysia MH - Methods MH - Soil Microbiology MH - Time Factors MH - Water Microbiology PT - JOURNAL ARTICLE DA - 700709 DP - 1970 May IS - 0002-9637 TA - Am J Trop Med Hyg PG - 485-92 SB - A SB - M CY - UNITED STATES IP - 3 VI - 19 JC - 3ZQ EM - 7008 PMID- 5446317 CU - 90 SO - Am J Trop Med Hyg 1970 May;19(3):485-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 70187262 AU - Decker MJ AU - Freeman MJ AU - Morter RL TI - Evaluation of mechanisms of leptospiral hemolytic anemia. LA - Eng MH - Anemia, Hemolytic/etiology/*veterinary MH - Animal MH - Antibodies/analysis MH - Antigen-Antibody Reactions MH - Antigens/analysis MH - Cold MH - Culture Media MH - Erythrocytes/immunology MH - Guinea Pigs MH - Hamsters MH - Hemagglutination Tests/veterinary MH - Hemolysins/analysis MH - Injections, Subcutaneous MH - Leptospira/growth & development/immunology MH - Leptospirosis/immunology/*veterinary MH - Rabbits MH - Sheep MH - Sheep Diseases/*etiology MH - Tissue Culture PT - JOURNAL ARTICLE DA - 700706 DP - 1970 May IS - 0002-9645 TA - Am J Vet Res PG - 873-8 SB - M CY - UNITED STATES IP - 5 VI - 31 JC - 40C EM - 7008 PMID- 5445315 SO - Am J Vet Res 1970 May;31(5):873-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 70254045 AU - Pupkevich-Diamant IaS TI - [Clinical forms and clinical classification of leptospiral diseases] LA - Rus MH - English Abstract MH - Human MH - Leptospirosis/*classification PT - JOURNAL ARTICLE DA - 700922 DP - 1970 May IS - 0023-2149 TA - Klin Med (Mosk) PG - 102-9 CY - USSR IP - 5 VI - 48 JC - KW2 EM - 7011 PMID- 5434055 TT - O klinicheskikh formakh i klinicheskov klassifikatsii leptospiroznykh zabolevanii. SO - Klin Med (Mosk) 1970 May;48(5):102-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 70281990 AU - Manev C AU - Siromashkova M TI - Comparative studies on antigen extracts from some Bulgarian leptospira strains. LA - Eng MH - Agar MH - Agglutination Tests MH - Alcohol, Ethyl MH - Animal MH - Antigens/analysis/*isolation & purification MH - Bile Acids and Salts MH - Bulgaria MH - Carbohydrates/analysis MH - Chromatography, Paper MH - Immune Sera MH - Immunochemistry MH - Immunodiffusion MH - Immunoelectrophoresis MH - Leptospira/*immunology MH - Nitrogen/analysis MH - Precipitation MH - Rabbits MH - Species Specificity PT - JOURNAL ARTICLE DA - 701023 DP - 1970 May TA - Zentralbl Bakteriol [Orig] PG - 526-32 SB - M CY - GERMANY, WEST IP - 4 VI - 213 JC - Y4Y EM - 7012 PMID- 4989489 CU - 91 SO - Zentralbl Bakteriol [Orig] 1970 May;213(4):526-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70227757 AU - Sefer M AU - Verenca C AU - Sobescianschi C TI - [Practical procedures for the preservation of Leptospira cultures] LA - Rum MH - Bacteriological Techniques MH - Culture Media MH - English Abstract MH - *Leptospira MH - *Preservation, Biological PT - JOURNAL ARTICLE DA - 700821 DP - 1970 May-Jun IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 271-3 CY - ROMANIA IP - 3 VI - 15 JC - MXQ EM - 7010 PMID- 4913187 CU - 90 TT - Procedee practice pentru conservarea culturilor de leptospire. SO - Microbiol Parazitol Epidemiol (Bucur) 1970 May-Jun;15(3):271-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 70229562 AU - Derrick EH TI - Medical research--a continuing challenge. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - *Arthritis, Rheumatoid/etiology MH - *Asthma/etiology MH - Australia MH - Child MH - Child, Preschool MH - Encephalitis MH - Female MH - Human MH - Infant MH - Infant, Newborn MH - Leptospirosis MH - Male MH - Middle Age MH - *Psoriasis/etiology MH - *Research MH - Typhus, Epidemic Louse-Borne PT - JOURNAL ARTICLE DA - 700826 DP - 1970 Apr 25 IS - 0025-729X TA - Med J Aust PG - 829-32 SB - M CY - AUSTRALIA IP - 17 VI - 1 JC - M26 EM - 7010 PMID- 5427043 SO - Med J Aust 1970 Apr 25;1(17):829-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70230964 AU - Michna SW TI - Leptospirosis. LA - Eng MH - Animal MH - Antibody Formation MH - Cat Diseases MH - Cats MH - Cattle MH - Cattle Diseases MH - Disease Reservoirs MH - Dog Diseases MH - Dogs MH - Goats MH - Horse Diseases MH - Horses MH - Human MH - Leptospira/growth & development MH - *Leptospirosis/diagnosis/drug therapy/epidemiology/etiology/prevention & control/veterinary MH - Sheep MH - Sheep Diseases MH - Swine MH - Swine Diseases PT - JOURNAL ARTICLE PT - REVIEW DA - 700826 DP - 1970 Apr 25 IS - 0042-4900 TA - Vet Rec PG - 484-96 SB - M CY - ENGLAND IP - 17 VI - 86 JC - XBS EM - 7010 RF - 202 PMID- 4913477 CU - 90 SO - Vet Rec 1970 Apr 25;86(17):484-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 70162900 AU - Paar D AU - Fonk I AU - Cohnen G AU - Heimsoth V AU - Debusmann ER AU - Bock KD TI - [Blood coagulation studies during the immunizing phase of leptospirosis with hemorrhagic disease course] LA - Ger MH - Adult MH - *Blood Coagulation MH - Blood Coagulation Disorders/etiology MH - Factor V/analysis MH - Fibrinogen/analysis MH - Human MH - Male MH - Weil's Disease/*blood/complications/immunology/mortality PT - JOURNAL ARTICLE DA - 700603 DP - 1970 Apr 24 IS - 0012-0472 TA - Dtsch Med Wochenschr PG - 954-8 SB - M CY - GERMANY, WEST IP - 17 VI - 95 JC - ECL EM - 7007 PMID- 5439554 TT - Gerinnungsuntersuchungen wahrend der immunisierenden Phase von Leptospiren-Infektionen mit hamorrhagischer Verlaufsform. SO - Dtsch Med Wochenschr 1970 Apr 24;95(17):954-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 70231516 AU - Stallman ND AU - Allan BC TI - A survey of antibodies to Mycoplasma pneumoniae in Queensland. LA - Eng MH - Agglutination Tests MH - Antibodies/*analysis MH - Australia MH - Brucellosis/diagnosis MH - Complement Fixation Tests MH - Diagnosis, Differential MH - Female MH - Human MH - Infectious Mononucleosis/diagnosis MH - Influenza/diagnosis MH - Leptospirosis/diagnosis MH - Male MH - Mycoplasma/*immunology MH - Mycoplasma Infections/immunology MH - Ornithosis/diagnosis MH - Osteomyelitis/diagnosis MH - Q Fever/diagnosis PT - JOURNAL ARTICLE DA - 700826 DP - 1970 Apr 18 IS - 0025-729X TA - Med J Aust PG - 800-2 SB - M CY - AUSTRALIA IP - 16 VI - 1 JC - M26 EM - 7010 PMID- 5427638 SO - Med J Aust 1970 Apr 18;1(16):800-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 71042593 AU - Wolff E AU - Hergt R TI - [A single case of Batavia leptospirosis with an icteric course] LA - Ger MH - Case Report MH - English Abstract MH - Germany, East MH - Human MH - Male MH - Middle Age MH - Occupational Diseases MH - Seasons MH - Weil's Disease/complications/*epidemiology/etiology PT - JOURNAL ARTICLE DA - 710115 DP - 1970 Apr 16 IS - 0012-0219 TA - Dtsch Gesundheitsw PG - 707-10 CY - GERMANY, EAST IP - 15 VI - 25 JC - ECG EM - 7102 PMID- 5483714 CU - 88 TT - Uber eine Eizelbeobachtung von Batavia-Leptospirose mit ikterischer Verlaufsform. SO - Dtsch Gesundheitsw 1970 Apr 16;25(15):707-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 70205121 AU - Thrower WR TI - Agriculture and the public health. LA - Eng MH - *Agriculture MH - Animal MH - Animal Feed MH - Antibiotics MH - Brucellosis/prevention & control MH - Cattle MH - Dairying MH - Drug Resistance, Microbial MH - Fascioliasis/prevention & control MH - Human MH - Hygiene MH - Immunization/veterinary MH - Leptospirosis/prevention & control MH - Pesticides/adverse effects MH - *Public Health MH - Sewage MH - Sheep MH - Swine MH - Zoonoses/prevention & control PT - JOURNAL ARTICLE DA - 700729 DP - 1970 Apr 11 IS - 0007-1447 TA - Br Med J PG - 69-74 SB - A SB - M CY - ENGLAND IP - 701 VI - 2 JC - B4W EM - 7009 PMID- 5463274 CU - 85 SO - Br Med J 1970 Apr 11;2(701):69-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 70201877 AU - Benoit C TI - [Acute leptospirosis in a dog] LA - Fre MH - Animal MH - Dog Diseases/*diagnosis/pathology MH - Dogs MH - Leptospirosis/diagnosis/pathology/*veterinary PT - JOURNAL ARTICLE DA - 700723 DP - 1970 Apr IS - 0008-5286 TA - Can Vet J PG - 81-3 CY - CANADA IP - 4 VI - 11 JC - CLS EM - 7009 PMID- 5463197 CU - 85 TT - Leptospiroase aigue chez un chien. SO - Can Vet J 1970 Apr;11(4):81-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 70175105 AU - Busch LA TI - News rom the National Communicable Disease Center. Leptospirosis, 1965- 1968. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Animal MH - Cat Diseases/epidemiology MH - Cats MH - Cattle MH - Cattle Diseases/epidemiology MH - Child MH - Child, Preschool MH - Dog Diseases/epidemiology MH - Dogs MH - Female MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - Infant MH - Infant, Newborn MH - Leptospira canicola/pathogenicity MH - Leptospira interrogans/pathogenicity MH - Leptospirosis/drug therapy/*epidemiology/etiology/veterinary MH - Male MH - Middle Age MH - Rodent Diseases/epidemiology MH - Rodentia MH - Sex Factors MH - Swine MH - Swine Diseases/epidemiology MH - United States PT - JOURNAL ARTICLE DA - 700611 DP - 1970 Apr IS - 0022-1899 TA - J Infect Dis PG - 458-60 SB - A SB - M CY - UNITED STATES IP - 4 VI - 121 JC - IH3 EM - 7008 PMID- 5462405 CU - 88 SO - J Infect Dis 1970 Apr;121(4):458-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70253598 AU - Sullivan ND TI - Experimental infection of pregnant cows with Leptospira hardjo. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies MH - Biological Assay MH - Cattle MH - Cattle Diseases/*complications MH - Female MH - Guinea Pigs MH - Leptospirosis/complications/*veterinary MH - Pregnancy MH - Pregnancy Complications, Infectious/*veterinary MH - Serotyping PT - JOURNAL ARTICLE DA - 700922 DP - 1970 Apr IS - 0005-0423 TA - Aust Vet J PG - 123-5 SB - M CY - AUSTRALIA IP - 4 VI - 46 JC - 9IE EM - 7011 PMID- 5433867 SO - Aust Vet J 1970 Apr;46(4):123-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70253597 AU - Sullivan ND TI - Experimental infection of cattle with Leptospira hardjo. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/analysis MH - Body Temperature MH - Cattle MH - Cattle Diseases/*microbiology MH - Leptospira/isolation & purification/pathogenicity MH - Leptospirosis/immunology/microbiology/*veterinary MH - Male MH - Rectum PT - JOURNAL ARTICLE DA - 700922 DP - 1970 Apr IS - 0005-0423 TA - Aust Vet J PG - 121-2 SB - M CY - AUSTRALIA IP - 4 VI - 46 JC - 9IE EM - 7011 PMID- 5433866 SO - Aust Vet J 1970 Apr;46(4):121-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70215581 AU - Rao GS AU - Surendran NS TI - Incidence and serotypes of bovine leptospira in Andhra Pradesh. LA - Eng MH - Abortion, Veterinary MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Female MH - India MH - Leptospira/*classification MH - Leptospirosis/epidemiology/*veterinary MH - Pregnancy MH - Serotyping PT - JOURNAL ARTICLE DA - 700810 DP - 1970 Apr IS - 0019-6479 TA - Indian Vet J PG - 296-8 CY - INDIA IP - 4 VI - 47 JC - GM9 EM - 7009 PMID- 5423934 CU - 88 SO - Indian Vet J 1970 Apr;47(4):296-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 70201767 AU - Burton G AU - Blenden DC AU - Goldberg HS TI - Naphthylamidase activity of Leptospira. LA - Eng MH - Alanine/metabolism MH - Aminopeptidases/*metabolism MH - Colorimetry MH - Culture Media MH - Hydrogen-Ion Concentration MH - Leptospira/classification/*enzymology/metabolism/pathogenicity MH - Leucine/metabolism MH - Leucine Aminopeptidase/metabolism MH - Naphthalenes/metabolism MH - Serotyping MH - Spectrophotometry MH - Temperature PT - JOURNAL ARTICLE DA - 700723 DP - 1970 Apr IS - 0003-6919 TA - Appl Microbiol PG - 586-8 SB - M CY - UNITED STATES IP - 4 VI - 19 JC - 6K0 EM - 7009 PMID- 5418939 SO - Appl Microbiol 1970 Apr;19(4):586-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 70231471 AU - Hayes JM AU - White CA Jr AU - Johnson AH TI - Leptospirosis in man and his best friend. A case report. LA - Eng MH - Adult MH - Animal MH - *Dog Diseases MH - Dogs MH - Human MH - Leptospirosis/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 700826 DP - 1970 Apr IS - 0038-3139 TA - J S C Med Assoc PG - 99-101 CY - UNITED STATES IP - 4 VI - 66 JC - K0N EM - 7010 PMID- 5269641 CU - 88 SO - J S C Med Assoc 1970 Apr;66(4):99-101 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 70281470 AU - Liceras de Hidalgo J AU - Hidalgo R TI - [Leptopirosis in cattle and slaughtermen of Tumbes, Peru] LA - Spa MH - *Abattoirs MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - English Abstract MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology MH - Occupational Diseases/*epidemiology MH - Peru MH - Serodiagnosis MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 701023 DP - 1970 Apr IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 297-306 CY - UNITED STATES IP - 4 VI - 68 JC - AGG EM - 7012 PMID- 4247867 CU - 92 TT - Leptospirosis en el ganado y matarifes de Tumbes, Peru. SO - Bol Oficina Sanit Panam 1970 Apr;68(4):297-306 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 70176804 AU - Dozsa L AU - Sahu S TI - Endometrial changes in nonpregnant ewes infected with Leptospira pomona. LA - Eng MH - Animal MH - Cell Line MH - Endometrium/microbiology/*pathology MH - Female MH - Fluorescent Antibody Technique MH - Guinea Pigs MH - Kidney MH - Leptospira/growth & development/isolation & purification MH - Leptospirosis/pathology/*veterinary MH - Sheep MH - Sheep Diseases/*pathology MH - Staining MH - Tissue Culture MH - Uterus/microbiology PT - JOURNAL ARTICLE DA - 700615 DP - 1970 Apr IS - 0010-8901 TA - Cornell Vet PG - 254-64 SB - M CY - UNITED STATES IP - 2 VI - 60 JC - DRI EM - 7008 PMID- 4191788 CU - 95 SO - Cornell Vet 1970 Apr;60(2):254-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70213931 AU - Wolff F AU - Kruger W TI - [Occupational medical significance of swine leptospirosis] LA - Ger MH - Agricultural Workers' Diseases/*epidemiology/prevention & control MH - Animal MH - English Abstract MH - Germany, East MH - Human MH - Leptospirosis/epidemiology/prevention & control/*veterinary MH - Male MH - Swine MH - Swine Diseases/*complications MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 700810 DP - 1970 Mar 13 IS - 0012-0219 TA - Dtsch Gesundheitsw PG - 460-3 CY - GERMANY, EAST IP - 10 VI - 25 JC - ECG EM - 7009 PMID- 5463666 CU - 88 TT - Ein Beitrag zur arbeitsmedizinischen Bedeutung der Schweineleptospirose. SO - Dtsch Gesundheitsw 1970 Mar 13;25(10):460-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71284046 AU - Topciu V AU - Spinu I AU - Hang Quy TT AU - Dung DT AU - Hung VV TI - Incidence of leptospirae in dogs in North Vietnam. LA - Eng MH - Age Factors MH - Agglutination Tests MH - Animal MH - Bacteriuria/microbiology MH - Diagnosis, Differential MH - Disease Reservoirs MH - Dog Diseases/diagnosis/*epidemiology MH - Dogs MH - Guinea Pigs MH - Immune Sera MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/*veterinary MH - Rats MH - Serotyping MH - Vietnam MH - Zoonoses PT - JOURNAL ARTICLE DA - 711106 DP - 1970 Mar-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 325-30 CY - ROMANIA IP - 1 VI - 29 JC - 8EM EM - 7112 PMID- 5535232 CU - 88 SO - Arch Roum Pathol Exp Microbiol 1970 Mar-Jun;29(1):325-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71208404 AU - Magalhaes M AU - Veras A TI - [Serological aspects of leptospirosis in Recife] LA - Por MH - *Antibodies MH - Brazil MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Serotyping PT - JOURNAL ARTICLE DA - 710723 DP - 1970 Mar-Apr IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 112-4 CY - BRAZIL IP - 2 VI - 12 JC - S9D EM - 7109 PMID- 5517814 CU - 88 TT - Aspectos sorologicos da leptospirose no Recife. SO - Rev Inst Med Trop Sao Paulo 1970 Mar-Apr;12(2):112-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 70202373 AU - Lesnikov AL TI - [Leptospiral meningitis--an occupational disease of meat-processing industry and animal husbandry workers] LA - Rus MH - Adolescence MH - Adult MH - *Agricultural Workers' Diseases MH - Animal MH - English Abstract MH - Human MH - Leptospirosis/*etiology MH - *Meat-Packing Industry MH - Meningitis/*microbiology MH - *Occupational Diseases MH - Zoonoses PT - JOURNAL ARTICLE DA - 700723 DP - 1970 Mar IS - 0038-5077 TA - Sov Med PG - 128-31 CY - USSR IP - 3 VI - 33 JC - UW7 EM - 7009 PMID- 5463211 CU - 85 TT - Leptospiroznye meningity--professional'noe zabolevanie rabochikh miasccbrabatyvaiushchei promyshlennosti i zhivotnovodcheskikh khoziaistv. SO - Sov Med 1970 Mar;33(3):128-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 70286863 AU - Kida H AU - Yanagawa R TI - Mutation of growth of leptospires in Shenberg's medium. LA - Eng MH - Agglutination Tests MH - Animal MH - *Culture Media MH - *Genetics, Microbial MH - Guinea Pigs MH - Immunodiffusion MH - Leptospira/*growth & development/pathogenicity MH - *Mutation MH - Virulence PT - JOURNAL ARTICLE DA - 701030 DP - 1970 Mar IS - 0047-1917 TA - Jpn J Vet Res PG - 1-7 CY - JAPAN IP - 1 VI - 18 JC - KRG EM - 7012 PMID- 4989727 CU - 91 SO - Jpn J Vet Res 1970 Mar;18(1):1-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 70134842 AU - Bigler WJ AU - Collins TE AU - Nichols JB AU - Galton MM AU - Prather EC TI - Trends of sporadic leptospirosis in Florida. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Agglutination Tests MH - Animal MH - Child MH - Disease Outbreaks MH - Dog Diseases/diagnosis MH - Dogs MH - Florida MH - Human MH - Leptospira/isolation & purification MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/etiology/veterinary MH - Middle Age MH - United States PT - JOURNAL ARTICLE DA - 700424 DP - 1970 Mar IS - 0094-6214 TA - Public Health Rep PG - 225-32 SB - A SB - M CY - UNITED STATES IP - 3 VI - 85 JC - PHR EM - 7006 PMID- 4984882 CU - 91 SO - Public Health Rep 1970 Mar;85(3):225-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 71284047 AU - Topciu V AU - Spinu I AU - Hang Quy TT TI - The rodent reservoir of leptospirae in North Vietnam. LA - Eng MH - Age Factors MH - Agglutination Tests MH - Animal MH - Bacteriological Techniques MH - Bacteriuria/microbiology MH - Carrier State MH - Diagnosis, Differential MH - Disease Reservoirs/*epidemiology MH - Female MH - Guinea Pigs MH - Kidney/microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/*veterinary MH - Male MH - Rats MH - Rodent Diseases/diagnosis/*epidemiology MH - Septicemia MH - Serotyping MH - Sex Factors MH - Species Specificity MH - Vietnam MH - Zoonoses PT - JOURNAL ARTICLE DA - 711106 DP - 1970 Mar-Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 331-8 CY - ROMANIA IP - 1 VI - 29 JC - 8EM EM - 7112 PMID- 4936244 CU - 90 SO - Arch Roum Pathol Exp Microbiol 1970 Mar-Jun;29(1):331-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 72085071 AU - Hudemann H AU - Maas G TI - [Epidemiologic studies of leptospirosis and listeriosis in an agricultural region] LA - Ger MH - Agricultural Workers' Diseases/*epidemiology MH - Animal MH - Antibody Formation MH - Communicable Diseases/diagnosis MH - Disease Outbreaks MH - English Abstract MH - Female MH - Germany, East MH - Health Surveys MH - Human MH - Leptospirosis/*immunology MH - Listeria Infections/*immunology MH - Pregnancy MH - Rural Health MH - Serodiagnosis MH - Serotyping MH - Sheep MH - Swine PT - JOURNAL ARTICLE DA - 720322 DP - 1970 Feb 27 IS - 0012-0219 TA - Dtsch Gesundheitsw PG - 362-5 CY - GERMANY, EAST IP - 8 VI - 25 JC - ECG EM - 7205 PMID- 5535633 CU - 88 TT - Epidemiologische Untersuchungen auf Leptospirose und Listeriose in einem landwirtschaftlich strukturierten Kreis. SO - Dtsch Gesundheitsw 1970 Feb 27;25(8):362-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 70138948 AU - Turner LH AU - Mohun AF TI - Leptospirosis. LA - Eng MH - Antigen-Antibody Reactions MH - Complement Fixation Tests MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis MH - Meningitis/*etiology PT - JOURNAL ARTICLE DA - 700430 DP - 1970 Feb 14 IS - 0007-1447 TA - Br Med J PG - 433-4 SB - A SB - M CY - ENGLAND IP - 693 VI - 1 JC - B4W EM - 7006 PMID- 5434671 SO - Br Med J 1970 Feb 14;1(693):433-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 71231019 AU - Cohnen G AU - Schriever O AU - Fonk I AU - Paar D AU - Linzenmeier G TI - [Serum protein changes in infection with Leptospira icterohaemorrhagiae] LA - Ger MH - Adult MH - Autoanalysis MH - Beta-Globulins/analysis MH - Blood Protein Electrophoresis MH - Blood Proteins/*analysis MH - C-Reactive Protein/analysis MH - Ceruloplasmin/analysis MH - Complement Fixation Tests MH - Diagnosis, Differential MH - Glycoproteins/analysis MH - Haptoglobins/analysis MH - Hepatitis A/blood MH - Human MH - IgA/analysis MH - IgG/analysis MH - IgM/analysis MH - Immunodiffusion MH - Immunoglobulins/analysis MH - Leptospira interrogans/classification/*isolation & purification MH - Leptospirosis/*blood/diagnosis MH - Lipoproteins/analysis MH - Macroglobulins/analysis MH - Male MH - Paper MH - Pneumonia, Lobar/blood MH - Serotyping MH - Serum Albumin/analysis MH - Serum Globulins/analysis MH - Transferrin/analysis MH - Trypsin Inhibitors/analysis PT - JOURNAL ARTICLE DA - 710813 DP - 1970 Feb 13 IS - 0025-8458 TA - Med Klin PG - 289-92 SB - M CY - GERMANY, WEST IP - 7 VI - 65 JC - M4E EM - 7110 PMID- 4103811 CU - 95 TT - Serumproteinveranderungen bei Infektion mit Leptospira icterohaemorrhagiae. SO - Med Klin 1970 Feb 13;65(7):289-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 70135799 AU - Barbier P AU - Lataste-Dorolle C AU - Ryter A TI - [Recurrent icterus and leptospirosis. Importance of a full story (Bataviae)] LA - Fre MH - Agglutination Tests MH - Antibodies/analysis MH - Asia, Southeastern MH - Cholestasis/complications/etiology MH - English Abstract MH - Fluorescent Antibody Technique MH - Human MH - Leptospira/pathogenicity MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/complications/diagnosis/epidemiology/immunology/*microbiol ogy MH - Male MH - *Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 700427 DP - 1970 Feb 7 IS - 0032-7867 TA - Presse Med PG - 307-10 SB - M CY - FRANCE IP - 7 VI - 78 JC - PLP EM - 7006 PMID- 4907366 CU - 90 TT - Ictere a repetition et leptospirose. Importance d'un rappel anamnestique Bataviae. SO - Presse Med 1970 Feb 7;78(7):307-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 72114599 AU - Shenberg E AU - Birnbaum S AU - Torten M AU - Almog H AU - Levy S AU - Lindenbaum I TI - [Clinical and epidemiological description of a case of human leptospirosis caused by the serotype canicola] LA - Heb MH - Adult MH - Animal MH - Dog Diseases MH - Dogs MH - English Abstract MH - Human MH - Leptospira canicola/*isolation & purification MH - Leptospirosis/diagnosis/*microbiology MH - Male PT - JOURNAL ARTICLE DA - 720501 DP - 1970 Feb 1 IS - 0017-7768 TA - Harefuah PG - 114-5 CY - ISRAEL IP - 3 VI - 78 JC - FZF EM - 7206 PMID- 5535698 CU - 85 SO - Harefuah 1970 Feb 1;78(3):114-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 70229303 AU - Lebeau A AU - Lamouroux J TI - [Vaccinations in canine medicine] LA - Fre MH - Animal MH - Distemper/prevention & control MH - Dog Diseases/*prevention & control MH - Dogs MH - Hepatitis, Animal/prevention & control MH - Immunization, Passive MH - Leptospirosis/prevention & control/veterinary MH - Rabies/prevention & control MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 700826 DP - 1970 Feb IS - 0001-4192 TA - Bull Acad Vet Fr PG - 85-8 CY - FRANCE IP - 2 VI - 43 JC - BA8 EM - 7010 PMID- 5464009 CU - 85 TT - Les vaccinations en medecine canine. SO - Bull Acad Vet Fr 1970 Feb;43(2):85-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70209122 AU - Liubashenko SIa AU - Zaichenko AS TI - [A modified method of diagnosing leptospirosis in swine] LA - Rus MH - Animal MH - Complement Fixation Tests/veterinary MH - Leptospirosis/*veterinary MH - Methods MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 700805 DP - 1970 Feb IS - 0042-4846 TA - Veterinariia PG - 98-100 CY - USSR VI - 2 JC - XCC EM - 7009 PMID- 5463447 CU - 90 TT - Modifitsirovannyi sposob diagnostiki leptospiroza svinei. SO - Veterinariia 1970 Feb;2:98-100 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70209097 AU - Drogun AG AU - Shorokkov VV AU - Soloshenko IZ AU - Petrov EM TI - [Pathomorphology of leptospirosis in swine in spontaneous infection] LA - Rus MH - Animal MH - Kidney/pathology MH - Leptospirosis/*veterinary MH - Liver/pathology MH - Swine MH - Swine Diseases/*pathology PT - JOURNAL ARTICLE DA - 700805 DP - 1970 Feb IS - 0042-4846 TA - Veterinariia PG - 47-9 CY - USSR VI - 2 JC - XCC EM - 7009 PMID- 5463427 CU - 85 TT - Patomorfologiia leptospiroza svinei pri spontannom zarazhenii. SO - Veterinariia 1970 Feb;2:47-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [103 medline neighbors] UI - 70113372 AU - Miller NG AU - Froehling RC AU - White RJ TI - Activity of leptospires and their products on L cell monolayers. LA - Eng MH - Animal MH - Cell Line MH - Culture Media MH - Fibroblasts MH - Hemolysins/biosynthesis MH - Hyaluronidase/biosynthesis MH - In Vitro MH - *L Cells MH - Leptospira/*growth & development MH - Leptospirosis/etiology MH - Mammals MH - Mice MH - Phospholipases/isolation & purification MH - Virulence PT - JOURNAL ARTICLE DA - 700402 DP - 1970 Feb IS - 0002-9645 TA - Am J Vet Res PG - 371-7 SB - M CY - UNITED STATES IP - 2 VI - 31 JC - 40C EM - 7005 PMID- 5461150 CU - 85 SO - Am J Vet Res 1970 Feb;31(2):371-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 70258047 AU - Kasarov LB TI - Degradiation of the erythrocyte phospholipids and haemolysis of the erythrocytes of different animal species by leptospirae. LA - Eng MH - Animal MH - Calcium/pharmacology MH - Cattle MH - Cell Membrane/analysis MH - Chromatography, Thin Layer MH - Erythrocytes/*analysis MH - Guinea Pigs MH - *Hemolysis MH - Human MH - In Vitro MH - Leptospira/*enzymology MH - Lysophosphatidylcholines/analysis MH - Phosphatidylcholines/analysis MH - Phospholipids/analysis/*blood MH - Rabbits MH - Rats MH - Sheep MH - Sphingomyelins/analysis PT - JOURNAL ARTICLE DA - 700928 DP - 1970 Feb IS - 0022-2615 TA - J Med Microbiol PG - 29-37 SB - M CY - ENGLAND IP - 1 VI - 3 JC - J2N EM - 7011 PMID- 5448881 SO - J Med Microbiol 1970 Feb;3(1):29-37 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 70213378 AU - Johnson ES AU - Muthu A AU - Selvaraj S TI - Leptospira grippotyphosa. LA - Eng MH - Adult MH - Human MH - India MH - *Leptospira/classification MH - *Leptospirosis/epidemiology MH - Male PT - JOURNAL ARTICLE DA - 700810 DP - 1970 Feb IS - 0004-5772 TA - J Assoc Physicians India PG - 301-3 CY - INDIA IP - 2 VI - 18 JC - HG7 EM - 7009 PMID- 5423044 CU - 88 SO - J Assoc Physicians India 1970 Feb;18(2):301-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70128209 AU - Du Plessis JL AU - Dupouey P AU - Lataste-Dorolle C AU - Faure M TI - [Antigenic structures of leptospirae, comparative study of results obtained by several immunologic methods] LA - Fre MH - Agglutination Tests MH - Animal MH - Antigens/analysis MH - Complement Fixation Tests MH - English Abstract MH - Fluorescent Antibody Technique MH - Human MH - Immune Sera MH - Immunodiffusion MH - Leptospira/*immunology MH - Leptospirosis/immunology MH - Rabbits MH - *Serotyping PT - JOURNAL ARTICLE DA - 700415 DP - 1970 Feb IS - 0020-2444 TA - Ann Inst Pasteur (Paris) PG - 179-90 SB - M CY - FRANCE IP - 2 VI - 118 JC - 58Y EM - 7006 PMID- 4984611 CU - 91 TT - Structure antigenique des leptospires, comparaison des resultats donnes par plusieurs methodes immunologiques. SO - Ann Inst Pasteur (Paris) 1970 Feb;118(2):179-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70087931 AU - Ross CA AU - Ives JC TI - Leptospirosis. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Complement Fixation Tests MH - England MH - Female MH - Human MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*diagnosis MH - Male MH - Meningitis/microbiology MH - Middle Age MH - Scotland MH - Wales MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 700305 DP - 1970 Jan 3 IS - 0007-1447 TA - Br Med J PG - 49 SB - A SB - M CY - ENGLAND IP - 687 VI - 1 JC - B4W EM - 7004 PMID- 5411608 CU - 88 SO - Br Med J 1970 Jan 3;1(687):49 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72126799 AU - Fazli SA TI - [Use of Leptospira Patoc I serotype as an antigen in the serodiagnosis of leptospirosis] LA - Tur MH - Agglutination Tests MH - Animal MH - *Antigens MH - Cats MH - Cattle MH - Dogs MH - English Abstract MH - Human MH - Leptospira/immunology MH - Leptospirosis/*diagnosis MH - Rabbits MH - Rats MH - Sciuridae MH - Serodiagnosis MH - Serotyping MH - Sheep PT - JOURNAL ARTICLE DA - 720509 DP - 1970 IS - 0049-4844 TA - Turk Hij Tecr Biyol Derg PG - 290-8 CY - TURKEY IP - 3 VI - 30 JC - WKI EM - 7207 PMID- 5535721 CU - 85 TT - Leptospirozun serodiagnozunda leptospira biflexa Patoc I susunun antijen olarak uygulanmasi. SO - Turk Hij Tecr Biyol Derg 1970;30(3):290-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71127442 AU - Jamieson S AU - Davidson RM AU - Salisbury RM TI - Leptospirosis in New Zealand. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - New Zealand MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 710415 DP - 1970 Jan-Feb IS - 0300-9823 TA - Bull Off Int Epizoot PG - 81-92 CY - FRANCE IP - 1 VI - 73 JC - BR4 EM - 7106 PMID- 5533723 CU - 88 SO - Bull Off Int Epizoot 1970 Jan-Feb;73(1):81-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71127441 TI - A review of the leptospiroses of domestic animals in Australia. LA - Eng MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/*epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - Leptospirosis/*epidemiology/veterinary MH - Rats MH - Rodent Diseases/epidemiology MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 710415 DP - 1970 Jan-Feb IS - 0300-9823 TA - Bull Off Int Epizoot PG - 67-80 CY - FRANCE IP - 1 VI - 73 JC - BR4 EM - 7106 PMID- 5533722 CU - 88 NI - A SO - Bull Off Int Epizoot 1970 Jan-Feb;73(1):67-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71127439 AU - Yanagawa R TI - Leptospirosis in Japan. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Horse Diseases/*epidemiology MH - Horses MH - Japan MH - Leptospirosis/*epidemiology MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 710415 DP - 1970 Jan-Feb IS - 0300-9823 TA - Bull Off Int Epizoot PG - 59-65 CY - FRANCE IP - 1 VI - 73 JC - BR4 EM - 7106 PMID- 5533720 CU - 88 SO - Bull Off Int Epizoot 1970 Jan-Feb;73(1):59-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 71127438 AU - Ryu E TI - Rapid microscopic agglutination test for Leptospira without non- specific reaction. LA - Eng MH - Animal MH - Cattle MH - Dogs MH - *Hemagglutination Tests MH - Leptospirosis/*diagnosis/veterinary MH - Taiwan PT - JOURNAL ARTICLE DA - 710415 DP - 1970 Jan-Feb IS - 0300-9823 TA - Bull Off Int Epizoot PG - 49-58 CY - FRANCE IP - 1 VI - 73 JC - BR4 EM - 7106 PMID- 5533719 CU - 85 SO - Bull Off Int Epizoot 1970 Jan-Feb;73(1):49-58 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71127437 AU - Liu YP AU - Ryu E TI - Studies of leptospirosis in Taiwan (Republic of China). LA - Eng MH - Animal MH - Buffaloes MH - Cattle MH - Cattle Diseases/*epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - Leptospirosis/*epidemiology/veterinary MH - Rats MH - Rodent Diseases/epidemiology MH - Swine MH - Swine Diseases/*epidemiology MH - Taiwan PT - JOURNAL ARTICLE DA - 710415 DP - 1970 Jan-Feb IS - 0300-9823 TA - Bull Off Int Epizoot PG - 43-8 CY - FRANCE IP - 1 VI - 73 JC - BR4 EM - 7106 PMID- 5533718 CU - 88 SO - Bull Off Int Epizoot 1970 Jan-Feb;73(1):43-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71127436 AU - Subharngkasen S TI - Leptospirosis in Thailand. LA - Eng MH - Animal MH - Buffaloes MH - Cattle MH - Cattle Diseases/*epidemiology MH - Leptospirosis/*epidemiology MH - Swine MH - Swine Diseases/*epidemiology MH - Thailand PT - JOURNAL ARTICLE DA - 710415 DP - 1970 Jan-Feb IS - 0300-9823 TA - Bull Off Int Epizoot PG - 39-42 CY - FRANCE IP - 1 VI - 73 JC - BR4 EM - 7106 PMID- 5533717 CU - 88 SO - Bull Off Int Epizoot 1970 Jan-Feb;73(1):39-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71127435 AU - Rao CK TI - Epizootiology of leptospirosis in India. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Dog Diseases/epidemiology MH - Dogs MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - India MH - Leptospirosis/*epidemiology/veterinary MH - Rats MH - Rodent Diseases/epidemiology MH - Sheep MH - Sheep Diseases/epidemiology MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 710415 DP - 1970 Jan-Feb IS - 0300-9823 TA - Bull Off Int Epizoot PG - 35-8 CY - FRANCE IP - 1 VI - 73 JC - BR4 EM - 7106 PMID- 5533716 CU - 88 SO - Bull Off Int Epizoot 1970 Jan-Feb;73(1):35-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [19 medline neighbors] UI - 71127432 TI - [Recommendations of the O.I.E.-F.A.O. Regional Conference on Epizootics in Asia, the Far East and Oceania held in Canberra (Australia) 20-28 October 1969] LA - Mul MH - Animal MH - Avian Leukosis/*prevention & control MH - Foot-and-Mouth Disease/*prevention & control MH - Leptospirosis/*prevention & control MH - Mycoplasma Infections/*prevention & control MH - Rinderpest/*prevention & control PT - JOURNAL ARTICLE DA - 710415 DP - 1970 Jan-Feb IS - 0300-9823 TA - Bull Off Int Epizoot PG - 223-37 CY - FRANCE IP - 1 VI - 73 JC - BR4 EM - 7106 PMID- 5533713 CU - 85 NI - A SO - Bull Off Int Epizoot 1970 Jan-Feb;73(1):223-37 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71067502 AU - Fazli A TI - [A serological survey of leptospirosis in humans and in domestic and wild animals in Turkey] LA - Tur MH - Animal MH - *Disease Reservoirs MH - Dogs MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology/*veterinary MH - Rabbits MH - Rats MH - Turkey PT - JOURNAL ARTICLE DA - 710212 DP - 1970 IS - 0049-4844 TA - Turk Hij Tecr Biyol Derg PG - 155-84 CY - TURKEY IP - 2 VI - 30 JC - WKI EM - 7103 PMID- 5530990 CU - 88 TT - Turkiye'de insan, evcil hayvan ve yavani kemirici serumlarinda leptospira yonunden serolojik incelemeler. SO - Turk Hij Tecr Biyol Derg 1970;30(2):155-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 71017607 AU - Chorvath B AU - Fried M TI - Action of leptospiral lipases on purified serum lipoproteins. LA - Eng MH - Animal MH - Bile Acids and Salts/pharmacology MH - Calcium Chloride/pharmacology MH - Chromatography, Thin Layer MH - Emulsions MH - Hydrogen-Ion Concentration MH - Immune Sera MH - Leptospira/*enzymology/pathogenicity MH - Lipase/isolation & purification/*metabolism MH - Lipoproteins/isolation & purification/*metabolism MH - Potentiometry MH - Sodium Chloride/pharmacology MH - Swine MH - Triglycerides/metabolism MH - Ultracentrifugation PT - JOURNAL ARTICLE DA - 701212 DP - 1970 IS - 0015-5632 TA - Folia Microbiol (Praha) PG - 303-8 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 15 JC - F23 EM - 7101 PMID- 5529075 CU - 85 SO - Folia Microbiol (Praha) 1970;15(4):303-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 71166722 AU - Iakimenko SA TI - [Involvement of the eyes in anicteric leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Eye Diseases/*etiology MH - Human MH - Jaundice MH - Leptospirosis/*complications MH - Male PT - JOURNAL ARTICLE DA - 710609 DP - 1970 IS - 0030-0675 TA - Oftalmol Zh PG - 454-5 CY - USSR IP - 6 VI - 25 JC - OG8 EM - 7107 PMID- 5511000 TT - Zabolevanie glaz bezzheltushnym leptospirozom. SO - Oftalmol Zh 1970;25(6):454-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71152720 AU - Castellani Pastoris M AU - Babudieri B AU - Polster E TI - [Systematic study of some strains of Leptospira in drinking water] LA - Ita MH - Agglutination Tests MH - Antigen-Antibody Reactions MH - Antigens/*analysis MH - Cross Reactions MH - English Abstract MH - Italy MH - Leptospira/classification/immunology/*isolation & purification MH - Netherlands MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 710519 DP - 1970 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 270-9 SB - M CY - ITALY IP - 4 VI - 6 JC - 5BP EM - 7107 PMID- 5508162 TT - Studio sistematico di alcuni ceppi di leptospire acquicole. SO - Ann Ist Super Sanita 1970;6(4):270-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 71152718 AU - Babudieri B TI - The WHO-FAO Leptospira Reference Laboratory in Rome. LA - Eng MH - Diagnosis, Laboratory MH - Human MH - International Agencies MH - International Cooperation MH - Laboratories MH - Leptospira/*classification MH - Leptospirosis/*diagnosis MH - Weil's Disease/diagnosis MH - World Health Organization PT - JOURNAL ARTICLE DA - 710519 DP - 1970 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 215-56 SB - M CY - ITALY IP - 4 VI - 6 JC - 5BP EM - 7107 PMID- 5508160 SO - Ann Ist Super Sanita 1970;6(4):215-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [189 medline neighbors] UI - 71002301 AU - Chorvath B TI - Phospholipase A activity in Leptospira biflexa. LA - Eng MH - Chromatography, Thin Layer MH - Fatty Acids/metabolism MH - Leptospira/*enzymology MH - Phospholipases/*metabolism MH - Potentiometry PT - JOURNAL ARTICLE DA - 701120 DP - 1970 IS - 0006-3088 TA - Biologia (Bratisl) PG - 587-91 CY - CZECHOSLOVAKIA IP - 9 VI - 25 JC - A4G EM - 7101 PMID- 5506586 SO - Biologia (Bratisl) 1970;25(9):587-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 71127443 AU - Faine S TI - Epidemiology, diagnosis and control of leptospirosis in man. LA - Eng MH - Asia MH - Australia MH - Europe MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - New Zealand PT - JOURNAL ARTICLE DA - 710415 DP - 1970 Jan-Feb IS - 0300-9823 TA - Bull Off Int Epizoot PG - 93-9 CY - FRANCE IP - 1 VI - 73 JC - BR4 EM - 7106 PMID- 5501943 CU - 88 SO - Bull Off Int Epizoot 1970 Jan-Feb;73(1):93-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 71102511 AU - Graubmann HD AU - Dobbriner W AU - Radke W TI - [Studies of the presence of Leptospira pomona titers in sheep in the Schwerin region] LA - Ger MH - Agglutination Tests MH - Antibodies/analysis PT - JOURNAL ARTICLE DA - 710324 DP - 1970 IS - 0003-9055 TA - Arch Exp Veterinarmed PG - 777-80 SB - M CY - GERMANY, EAST IP - 3 VI - 24 JC - 70I EM - 7105 PMID- 5498052 CU - 84 TT - Untersuchungen uber das Vorkommen von Leptospira-pomona-Titern bei Schafen im Bezirk Schwerin. SO - Arch Exp Veterinarmed 1970;24(3):777-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 70230751 AU - Thin RN AU - Brown M AU - Stewart JB AU - Garrett CJ TI - Melioidosis: a report of ten cases. LA - Eng MH - Adult MH - Chloramphenicol/therapeutic use MH - Female MH - Human MH - Leptospirosis/complications MH - Lung Diseases/radiography MH - Male MH - *Melioidosis/complications/diagnosis/drug therapy/etiology/mortality/radiography MH - Penicillins/therapeutic use MH - Serodiagnosis MH - Streptomycin/therapeutic use MH - Tetracycline/therapeutic use PT - JOURNAL ARTICLE DA - 700826 DP - 1970 Jan IS - 0033-5622 TA - Q J Med PG - 115-27 SB - M CY - ENGLAND IP - 153 VI - 39 JC - QKZ EM - 7010 PMID- 5464044 CU - 85 SO - Q J Med 1970 Jan;39(153):115-27 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 70227312 AU - Chorvath B TI - Inhibition of leptospiral lipase by antilipase antibodies. LA - Eng MH - Animal MH - Antibodies/*pharmacology MH - Enzyme Repression MH - Immune Sera MH - Leptospira/*enzymology MH - Lipase/*antagonists & inhibitors MH - Neutralization Tests MH - Rabbits PT - JOURNAL ARTICLE DA - 700821 DP - 1970 IS - 0006-3088 TA - Biologia (Bratisl) PG - 147-52 CY - CZECHOSLOVAKIA IP - 3 VI - 25 JC - A4G EM - 7010 PMID- 5463980 CU - 85 SO - Biologia (Bratisl) 1970;25(3):147-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 70217988 AU - Rislakki V AU - Vasenius H TI - Further studies on leptospirosis in small rodents and shrews in Finland. A report of investigation made in 1963-64. LA - Eng MH - Animal MH - Finland MH - *Leptospira interrogans MH - Mice MH - Rats MH - Rodent Diseases/*diagnosis MH - Rodentia MH - Serodiagnosis MH - Trichinella MH - Trypanosoma MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 700811 DP - 1970 IS - 0044-605X TA - Acta Vet Scand PG - 133-5 CY - DENMARK IP - 1 VI - 11 JC - 27V EM - 7009 PMID- 5463868 CU - 85 SO - Acta Vet Scand 1970;11(1):133-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70137252 AU - Smith RE AU - Reynolds IM AU - Clark GW TI - Experimental leptospirosis in pregnant ewes. VII. Pathogenesis of fetal infection and mechanism of abortion. LA - Eng MH - *Abortion, Veterinary MH - Animal MH - Female MH - Fetal Death/*veterinary MH - Fetal Diseases/*veterinary MH - Leptospirosis/*veterinary MH - Placenta/pathology MH - Pregnancy MH - Pregnancy Complications, Infectious/*veterinary MH - Sheep MH - Sheep Diseases/*pathology PT - JOURNAL ARTICLE DA - 700428 DP - 1970 Jan IS - 0010-8901 TA - Cornell Vet PG - 40-52 SB - M CY - UNITED STATES IP - 1 VI - 60 JC - DRI EM - 7006 PMID- 5461545 CU - 85 SO - Cornell Vet 1970 Jan;60(1):40-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70133464 AU - Michna SW AU - Campbell RS TI - Leptospirosis in wild animals. LA - Eng MH - Animal MH - Carnivora MH - Cattle MH - Cattle Diseases/epidemiology MH - Deer MH - Human MH - Insectivora MH - Kidney/microbiology/pathology MH - Leptospirosis/epidemiology/pathology/*veterinary MH - Mice MH - Rats MH - Rodent Diseases/epidemiology MH - Rodentia MH - Scotland MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 700422 DP - 1970 Jan IS - 0021-9975 TA - J Comp Pathol PG - 101-6 SB - M CY - ENGLAND IP - 1 VI - 80 JC - HVB EM - 7006 PMID- 5461440 CU - 88 SO - J Comp Pathol 1970 Jan;80(1):101-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70116744 AU - Torten M AU - Birnbaum S AU - Klingberg MA AU - Shenberg E TI - Epidemiologic investigation of an outbreak of leptospirosis in the Upper Galilee, Israel. LA - Eng MH - Agricultural Workers' Diseases/epidemiology MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Outbreaks MH - Dog Diseases/epidemiology MH - Dogs MH - Human MH - Israel MH - Leptospirosis/*epidemiology/veterinary MH - Rodent Diseases/epidemiology MH - Serotyping MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 700406 DP - 1970 Jan IS - 0002-9262 TA - Am J Epidemiol PG - 52-8 SB - M CY - UNITED STATES IP - 1 VI - 91 JC - 3H3 EM - 7005 PMID- 5461191 CU - 88 SO - Am J Epidemiol 1970 Jan;91(1):52-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70187118 AU - Vysotskii BV AU - Polivanov VM AU - Kir'ianov EA TI - [Leptospirosis of the red heron] LA - Rus MH - Animal MH - *Bird Diseases MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 700702 DP - 1970 IS - 0042-4846 TA - Veterinariia PG - 67 CY - USSR VI - 3 JC - XCC EM - 7008 PMID- 5445248 TT - Leptospiroz ryzhikh tsapel'. SO - Veterinariia 1970;3:67 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70187098 AU - Zaichenko AS TI - [Autocalaved nutrient medium for culturing leptospira] LA - Rus MH - Animal MH - Blood MH - Cattle MH - *Culture Media MH - *Heat MH - Leptospira/*growth & development MH - Sheep MH - *Sterilization MH - Veterinary Medicine PT - JOURNAL ARTICLE DA - 700702 DP - 1970 IS - 0042-4846 TA - Veterinariia PG - 109-10 CY - USSR VI - 3 JC - XCC EM - 7008 PMID- 5445244 TT - Avtoklavirovannaia pitatel'naia sreda dlia kul'tivirovaniia leptospir. SO - Veterinariia 1970;3:109-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 70244010 AU - Brito de T AU - Penna DO AU - Hoshino S AU - Pereira VG AU - Caldas AC AU - Rothstein W TI - Cholestasis in human leptospirosis: a clinical, histochemical, biochemical and electron microscopy study based on liver biopsies. LA - Eng MH - Adolescence MH - Adult MH - Aminotransferases/blood MH - Bilirubin/blood MH - Biopsy MH - Cholestasis/enzymology/*pathology MH - English Abstract MH - Histocytochemistry MH - Human MH - Leptospirosis/complications/enzymology/*pathology MH - Liver/metabolism/pathology MH - Male MH - Microscopy, Electron MH - Microtomy MH - Serum Globulins/analysis MH - Succinate Dehydrogenase/analysis MH - Urea/blood PT - JOURNAL ARTICLE DA - 700911 DP - 1970 TA - Beitr Pathol Anat PG - 345-61 SB - M CY - GERMANY, WEST IP - 3 VI - 140 JC - 9NK EM - 7010 PMID- 5432310 CU - 89 SO - Beitr Pathol Anat 1970;140(3):345-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70241599 AU - Nasilowska M TI - [Attempts at obtaining polyvalent antigens for the diagnosis of leptospirosis] LA - Pol MH - Animal MH - *Antigens MH - Hemagglutination Tests MH - Human MH - Immune Sera MH - Leptospira/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis/immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 700909 DP - 1970 IS - 0033-2100 TA - Przegl Epidemiol PG - 81-91 CY - POLAND IP - 1 VI - 24 JC - Q8T EM - 7010 PMID- 5431391 TT - Proby otrzymania antygenow poliwalentnych do diagnostyki leptospiroz. SO - Przegl Epidemiol 1970;24(1):81-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70227324 AU - Plesko I AU - Lataste-Dorolle C TI - Intertype immunity relations of Leptospira strains belonging to the "Australis" serogroup. LA - Eng MH - Animal MH - Disease Models, Animal MH - Guinea Pigs MH - Hamsters MH - Leptospira/*immunology MH - Leptospirosis/immunology MH - Species Specificity PT - JOURNAL ARTICLE DA - 700821 DP - 1970 IS - 0006-3088 TA - Biologia (Bratisl) PG - 403-12 CY - CZECHOSLOVAKIA IP - 6 VI - 25 JC - A4G EM - 7010 PMID- 5426289 SO - Biologia (Bratisl) 1970;25(6):403-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [43 medline neighbors] UI - 70225452 AU - Oravec C AU - Cambelova J TI - Experimental biotherapy by leptospiral infection VI. Growth inhibition of syngenic mouse tumours after application of the L. biflexa Patoc I strain. LA - Eng MH - Adenocarcinoma/therapy MH - Animal MH - Carcinoma, Ehrlich Tumor/therapy MH - Female MH - *Leptospira MH - Leptospirosis/complications MH - Lymphoma/therapy MH - Male MH - Mice MH - Neoplasms, Experimental/complications/*therapy MH - Sarcoma, Experimental/therapy PT - JOURNAL ARTICLE DA - 700817 DP - 1970 IS - 0028-2685 TA - Neoplasma PG - 125-31 SB - M CY - CZECHOSLOVAKIA IP - 2 VI - 17 JC - NVO EM - 7010 PMID- 5425389 SO - Neoplasma 1970;17(2):125-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 70125675 AU - Henneberry RC AU - Cox CD TI - Beta-oxidation of fatty acids by Leptospira. LA - Eng MH - Acyltransferases/metabolism MH - Coenzyme A MH - Culture Media MH - Fatty Acids/*metabolism MH - Fatty Acids, Nonesterified/metabolism MH - Leptospira/enzymology/*metabolism MH - Ligases MH - Malate Dehydrogenase/metabolism MH - Oxygen Consumption PT - JOURNAL ARTICLE DA - 700410 DP - 1970 Jan IS - 0008-4166 TA - Can J Microbiol PG - 41-5 SB - M CY - CANADA IP - 1 VI - 16 JC - CJ3 EM - 7006 PMID- 5415967 SO - Can J Microbiol 1970 Jan;16(1):41-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 71101586 AU - Chang A AU - Faine S TI - Electron-microscopic evidence for reactions of axial filaments of Leptospira with IgM and IgG antibodies. LA - Eng PT - JOURNAL ARTICLE DA - 710323 DP - 1970 IS - 0042-9686 TA - Bull World Health Organ PG - 571-7 CY - SWITZERLAND IP - 4 VI - 43 JC - C80 EM - 7105 PMID- 5313069 CU - 89 SO - Bull World Health Organ 1970;43(4):571-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 70258921 AU - Kmety E AU - Galton MM AU - Sulzer CR TI - Further standardization of the agglutinin-absorption test in the serology of leptospires. LA - Eng MH - Absorption MH - Agglutination Tests MH - Antibodies MH - Antigens MH - Leptospira/*classification MH - Serotyping/*standards MH - Time Factors PT - JOURNAL ARTICLE DA - 700928 DP - 1970 IS - 0042-9686 TA - Bull World Health Organ PG - 733-8 CY - SWITZERLAND IP - 5 VI - 42 JC - C80 EM - 7011 PMID- 5311059 CU - 90 SO - Bull World Health Organ 1970;42(5):733-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 72009277 AU - Ivanov I TI - Double leptospira-carrying in a single individual of Micromys minutus. LA - Eng MH - Animal MH - *Disease Reservoirs MH - Leptospira/growth & development/*isolation & purification MH - Mice MH - Serotyping PT - JOURNAL ARTICLE DA - 711207 DP - 1970 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 280-2 CY - BULGARIA IP - 4 VI - 12 JC - F19 EM - 7201 PMID- 4999586 CU - 91 SO - Folia Med (Plovdiv) 1970;12(4):280-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 71060436 AU - Henneberry RC AU - Baseman JB AU - Cox CD TI - Growth of a water strain of Leptospira in synthetic media. LA - Eng MH - Acetates/pharmacology MH - Acids/analysis MH - Alcohol, Ethyl/analysis MH - Ammonium Compounds MH - Bacteriological Techniques MH - Calcium Chloride MH - Carbon Dioxide/metabolism MH - Caseins MH - Chromatography, Thin Layer MH - *Culture Media MH - Glycerin/analysis MH - Hydrogen-Ion Concentration MH - Leptospira/*growth & development/metabolism MH - Magnesium Sulfate MH - Manometry MH - Phosphates MH - Potassium Chloride MH - Protein Hydrolysates MH - Sodium MH - Sodium Chloride MH - Temperature MH - Thiamine MH - Vitamin B 12 MH - Water Microbiology PT - JOURNAL ARTICLE DA - 710206 DP - 1970 IS - 0003-6072 TA - Antonie Van Leeuwenhoek PG - 489-501 SB - M CY - NETHERLANDS IP - 4 VI - 36 JC - 6JE EM - 7103 PMID- 4922749 CU - 90 SO - Antonie Van Leeuwenhoek 1970;36(4):489-501 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [91 medline neighbors] UI - 70242784 AU - Jirovec O TI - [Natural foci of parasitic diseases of humans in central Europe] LA - Fre MH - Aedes MH - Animal MH - Animal Diseases MH - Birds MH - Cattle MH - Czechoslovakia MH - *Disease Reservoirs MH - *Disease Vectors MH - Encephalitis Viruses, Tick-Borne MH - Encephalitis, Tick-Borne/epidemiology MH - English Abstract MH - Europe, Eastern MH - Human MH - *Insect Vectors MH - Leptospirosis/epidemiology MH - Meningitis/epidemiology MH - Ornithosis/epidemiology MH - Parasitic Diseases/*epidemiology MH - Pneumonia, Pneumocystis carinii/epidemiology MH - Q Fever/epidemiology MH - Spirillum MH - Toxoplasmosis/epidemiology MH - Toxoplasmosis, Animal/epidemiology MH - Trichinosis/epidemiology MH - Tularemia/epidemiology PT - JOURNAL ARTICLE PT - REVIEW DA - 700910 DP - 1970 Jan-Feb IS - 0003-4150 TA - Ann Parasitol Hum Comp PG - 147-66 SB - M CY - FRANCE IP - 1 VI - 45 JC - 5TQ EM - 7010 RF - 50 PMID- 4914542 CU - 90 TT - Les foyers naturels des maladies parasitaires de l'homme en Europe centrale. SO - Ann Parasitol Hum Comp 1970 Jan-Feb;45(1):147-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 70183973 AU - Tolle A TI - [Milk as a nutrient] LA - Ger MH - Animal MH - Bacteriological Techniques MH - Cattle MH - Cattle Diseases MH - *Food Inspection MH - Germany, West MH - Leptospirosis/veterinary MH - Listeria Infections/veterinary MH - Mastitis, Bovine MH - *Milk/analysis/microbiology MH - *Nutrition MH - Refrigeration MH - Salmonella Infections, Animal MH - Toxoplasmosis, Animal MH - Zoonoses PT - JOURNAL ARTICLE DA - 700701 DP - 1970 TA - Zentralbl Bakteriol [Orig] PG - 291-303 SB - M CY - GERMANY, WEST IP - 2 VI - 212 JC - Y4Y EM - 7008 PMID- 4910451 CU - 90 TT - Milch als Nahrungsmittel. SO - Zentralbl Bakteriol [Orig] 1970;212(2):291-303 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 71287958 AU - Popova EM AU - Sosnitskii VI AU - Fedoseeva MF AU - Iachmenev NI TI - [Natural foci of leptospirosis in several regions of the North-West RSFSR and their manifestations] LA - Rus MH - Animal MH - *Disease Reservoirs MH - Leptospirosis/*epidemiology MH - Mice MH - Rodent Diseases/*epidemiology MH - Russia PT - JOURNAL ARTICLE DA - 711112 DP - 1970 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 190-201 CY - USSR VI - 37 JC - VZR EM - 7112 PMID- 4255059 CU - 92 TT - Pridodnye ochagi leptospirozov v nekotorykh raionakh Severo-Zapada RSFSR i ihk proiavliaemost. SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1970;37:190-201 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [105 medline neighbors] UI - 71287957 AU - Popova EM TI - [Detection of rare leptospiroses in the North-West RSFSR (Australia, autumnalis, batavia, javanika semarang)] LA - Rus MH - Adolescence MH - Adult MH - Human MH - Leptospirosis/*epidemiology/microbiology MH - Male MH - Middle Age MH - Russia PT - JOURNAL ARTICLE DA - 711112 DP - 1970 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 179-89 CY - USSR VI - 37 JC - VZR EM - 7112 PMID- 4255058 CU - 92 TT - Obnaruzhenie "redkikh" leptospirozov na Severo-zapade RSFSR (australia, autumnalis, bataviia, iavanika, semarang. SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1970;37:179-89 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 70191587 AU - Kingscote BF TI - Correlation of bedrock type with the geography of leptospirosis. LA - Eng MH - Animal MH - Animal Diseases/*epidemiology MH - Cattle MH - Cattle Diseases/epidemiology MH - Deer MH - Disease Outbreaks MH - *Disease Reservoirs MH - *Geography MH - *Geology MH - Hemagglutination Tests MH - Leptospira/classification MH - Leptospirosis/*veterinary MH - Ontario MH - Soil/analysis MH - Swine MH - Swine Diseases/epidemiology MH - Water/analysis PT - JOURNAL ARTICLE DA - 700709 DP - 1970 Jan IS - 0008-4050 TA - Can J Comp Med Vet Sci PG - 31-7 SB - M CY - CANADA IP - 1 VI - 34 JC - CI0 EM - 7008 PMID- 4246001 CU - 92 SO - Can J Comp Med Vet Sci 1970 Jan;34(1):31-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 70191582 AU - Chernesky SJ TI - A serological survey for canine leptospirosis in British Columbia. LA - Eng MH - Animal MH - Antibodies/*isolation & purification MH - British Columbia MH - Dog Diseases/*epidemiology MH - Dogs MH - Female MH - Hemagglutination Tests MH - Leptospirosis/*veterinary MH - Male MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 700709 DP - 1970 Jan IS - 0008-4050 TA - Can J Comp Med Vet Sci PG - 102-4 SB - M CY - CANADA IP - 1 VI - 34 JC - CI0 EM - 7008 PMID- 4245997 CU - 92 SO - Can J Comp Med Vet Sci 1970 Jan;34(1):102-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 71053438 AU - Turner LH TI - Leptospirosis. 3. Maintenance, isolation and demonstration of leptospires. LA - Eng MH - Agar MH - Animal MH - Blood/microbiology MH - Cerebrospinal Fluid/microbiology MH - Culture Media MH - Fluorescent Antibody Technique MH - Fluorouracil MH - Guinea Pigs MH - Hamsters MH - Kidney/pathology MH - Leptospira/growth & development/*isolation & purification MH - Leptospirosis/diagnosis/microbiology/pathology MH - Mice MH - Microscopy MH - Plasma MH - Rabbits MH - Rats MH - Serum Albumin, Bovine MH - Staining MH - Urine/microbiology MH - Water Microbiology PT - JOURNAL ARTICLE PT - REVIEW DA - 710123 DP - 1970 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 623-46 SB - M CY - ENGLAND IP - 4 VI - 64 JC - WBU EM - 7103 RF - 74 PMID- 4098633 CU - 95 SO - Trans R Soc Trop Med Hyg 1970;64(4):623-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70105261 AU - Crawford RP AU - McCulloch WF AU - Top FH Sr AU - Diesch SL TI - Epidemiologic studies of sporadic human cases of leptospirosis in Iowa, 1965-1968. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Animal MH - Antibiotics/therapeutic use MH - Antibodies/analysis MH - Child MH - Hemagglutination Tests MH - Human MH - Iowa MH - Leptospirosis/drug therapy/*epidemiology/etiology/immunology/veterinary MH - Meat-Packing Industry MH - Middle Age MH - Seasons MH - Serotyping MH - Zoonoses PT - JOURNAL ARTICLE DA - 700319 DP - 1969 Dec 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 2084-90 SB - M CY - UNITED STATES IP - 12 VI - 155 JC - HAV EM - 7005 PMID- 5392453 CU - 88 SO - J Am Vet Med Assoc 1969 Dec 15;155(12):2084-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 70092174 AU - Olsen CD TI - United States Public Health Service program for the control of abnormal milk. LA - Eng MH - Animal MH - Brucella/isolation & purification MH - Cattle MH - Female MH - *Food Contamination MH - Leptospira/isolation & purification MH - Mastitis, Bovine MH - Milk/*microbiology MH - Salmonella/isolation & purification MH - United States MH - *United States Public Health Service PT - JOURNAL ARTICLE DA - 700306 DP - 1969 Dec 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1978-81 SB - M CY - UNITED STATES IP - 12 VI - 155 JC - HAV EM - 7004 PMID- 5392165 CU - 85 SO - J Am Vet Med Assoc 1969 Dec 15;155(12):1978-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70092198 AU - Szatalowicz FT AU - Griffin TP AU - Stunkard JA TI - The international dimensions of leptospirosis. LA - Eng MH - Africa MH - Asia MH - Australia MH - Central America MH - Europe MH - Geography MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - North America MH - Serodiagnosis MH - South America PT - JOURNAL ARTICLE PT - REVIEW DA - 700306 DP - 1969 Dec 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 2122-32 SB - M CY - UNITED STATES IP - 12 VI - 155 JC - HAV EM - 7004 RF - 42 PMID- 4904476 CU - 90 SO - J Am Vet Med Assoc 1969 Dec 15;155(12):2122-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71140271 AU - Badoche-Sarniguet JM TI - [Etiologic diagnosis of strabismus with amblyopia] LA - Fre MH - Adult MH - Amblyopia/*etiology MH - Child MH - Child, Preschool MH - Chorioretinitis/*complications MH - Female MH - Human MH - Infant MH - Infant, Newborn MH - Leptospirosis/*complications MH - Male MH - Pregnancy MH - *Pregnancy Complications, Infectious MH - Strabismus/*etiology PT - JOURNAL ARTICLE DA - 710505 DP - 1969 Dec IS - 0081-1270 TA - Bull Soc Ophtalmol Fr PG - 1049-51 CY - FRANCE IP - 12 VI - 69 JC - C40 EM - 7106 PMID- 5402190 TT - Du diagnostic etiologique d'un strabisme avec amblyopie. SO - Bull Soc Ophtalmol Fr 1969 Dec;69(12):1049-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70182446 AU - Chulovskii IK TI - [The distribution of leptospirosis in an Omsk region area (data from serologic research)] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - Leptospira canicola MH - Leptospira interrogans MH - Leptospirosis/*epidemiology/*veterinary MH - Serodiagnosis MH - Sheep MH - Sheep Diseases/epidemiology MH - Siberia MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 700624 DP - 1969 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 100-4 SB - M CY - USSR IP - 12 VI - 46 JC - Y9O EM - 7008 PMID- 5393536 CU - 89 TT - Izuchenie rasprostraneniia leptospirozov na territorii omskoi oblasti (materialy serologicheskikh issledovanii) SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Dec;46(12):100-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70151423 AU - Fenske E AU - Fenske G TI - [Epidemiological studies on human infection with Leptospira tarassovi and Leptospira pomona] LA - Ger MH - *Abattoirs MH - Animal MH - Antibiotics/therapeutic use MH - English Abstract MH - Epidemiologic Methods MH - Female MH - Human MH - Leptospira/immunology MH - Leptospirosis/epidemiology/*immunology MH - Male MH - Serodiagnosis MH - Swine MH - Swine Diseases MH - Veterinary Medicine MH - *Zoonoses PT - JOURNAL ARTICLE DA - 700510 DP - 1969 Dec 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 892-7 CY - GERMANY, EAST IP - 23 VI - 24 JC - NGV EM - 7007 PMID- 5393095 CU - 88 TT - Epidemiologische Untersuchungen zur Infektion des Menschen mit Leptospira tarassovi und Leptospira pomona. SO - Monatsh Veterinarmed 1969 Dec 1;24(23):892-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70038064 AU - Carroll RE AU - Le Clair RA TI - Isolation of leptospiral serotype patoc from cattle in southern California. LA - Eng MH - Animal MH - California MH - Cattle MH - Cattle Diseases/*microbiology MH - Leptospira/*isolation & purification MH - Leptospirosis/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 700109 DP - 1969 Dec IS - 0002-9645 TA - Am J Vet Res PG - 2231-2 SB - M CY - UNITED STATES IP - 12 VI - 30 JC - 40C EM - 7002 PMID- 5389427 CU - 85 SO - Am J Vet Res 1969 Dec;30(12):2231-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 70183830 AU - Lev NA AU - Zil'berman ZI AU - Iurchakevich LP AU - Gordienko IuI TI - [Clinical picture of Reiter-Wegener syndrome complicated by leptotrichosis sepsis] LA - Rus MH - Case Report MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Reiter's Disease/*complications PT - JOURNAL ARTICLE DA - 700701 DP - 1969 Dec IS - 0040-3660 TA - Ter Arkh PG - 95-8 CY - USSR IP - 12 VI - 41 JC - VLU EM - 7008 PMID- 5382764 TT - K klinike sindroma reitera--vegenera, oslozhnennogo leptotrikhoznym sepsisom. SO - Ter Arkh 1969 Dec;41(12):95-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 70182448 AU - Samedov AS AU - Gosideeva SG TI - [Leptospiral ultrasonic polyvalent depot vaccine] LA - Rus MH - Animal MH - Antigens MH - *Bacterial Vaccines MH - English Abstract MH - Leptospira MH - Leptospira canicola MH - Leptospira interrogans MH - Leptospirosis/immunology/*prevention & control MH - Rabbits MH - Ultrasonics MH - Weil's Disease/prevention & control PT - JOURNAL ARTICLE DA - 700624 DP - 1969 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 109-13 SB - M CY - USSR IP - 12 VI - 46 JC - Y9O EM - 7008 PMID- 5382607 CU - 89 TT - Leptoopiroznaia ul'trazvukeovaia polivalentnaia depo-vaktsina. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Dec;46(12):109-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70209127 AU - Shmatkova AI TI - [Transmission of passive immunity to leptospirosis in swine] LA - Rus MH - Animal MH - Animals, Newborn/immunology MH - Female MH - *Immunity, Maternally-Acquired MH - Leptospirosis/*veterinary MH - Milk/*immunology MH - Pregnancy MH - Swine MH - Swine Diseases/*immunology PT - JOURNAL ARTICLE DA - 700805 DP - 1969 Dec IS - 0042-4846 TA - Veterinariia PG - 24-5 CY - USSR IP - 12 VI - 46 JC - XCC EM - 7009 PMID- 5375229 TT - O peredache passivnogo immuniteta protiv leptospiroza svinei. SO - Veterinariia 1969 Dec;46(12):24-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 70059976 TI - Diseases from Vietnam. LA - Eng MH - Acute Disease MH - Arbovirus Infections MH - Carrier State MH - Chikungunya Virus MH - Dengue MH - Leptospirosis MH - Malaria MH - Melioidosis MH - Military Medicine MH - Scrub Typhus MH - *Tropical Medicine MH - United States MH - Vietnam PT - JOURNAL ARTICLE DA - 700130 DP - 1969 Dec IS - 0008-1264 TA - Calif Med PG - 461-6 CY - UNITED STATES IP - 6 VI - 111 JC - CFU EM - 7003 PMID- 5358980 NI - A SO - Calif Med 1969 Dec;111(6):461-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 70200625 AU - Tsai CC AU - Fresh JW TI - Leptospirosis on Orchid Island, Taiwan. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Animal Diseases/*epidemiology MH - Carnivora MH - Child MH - Child, Preschool MH - Female MH - Fluorescent Antibody Technique MH - Geography MH - Hemagglutination Tests MH - Human MH - Infant MH - Infant, Newborn MH - Leptospira/classification MH - Leptospirosis/*epidemiology/*veterinary MH - Male MH - Middle Age MH - Occupations MH - Rats MH - Rodent Diseases/epidemiology MH - Serotyping MH - Taiwan PT - JOURNAL ARTICLE DA - 700717 DP - 1969 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 456-61 SB - M CY - NETHERLANDS IP - 4 VI - 21 JC - WGJ EM - 7009 PMID- 4911336 CU - 90 SO - Trop Geogr Med 1969 Dec;21(4):456-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 70127306 AU - Khomiakov AI AU - Fetisova NA AU - Fetisov OA TI - [Various epidemiologic patterns of leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Animal MH - Disease Reservoirs/epidemiology MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Rodent Diseases/epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 700414 DP - 1969 Nov TA - Zh Mikrobiol Epidemiol Immunobiol PG - 140 SB - M CY - USSR IP - 11 VI - 46 JC - Y9O EM - 7006 PMID- 5392788 CU - 89 TT - K voprosu o nekotorykh epidemiologicheskikh zakonomernostiakh leptospiroznykh zabolevanii. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Nov;46(11):140 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 70280686 AU - Babudieri B TI - [International public health work against trachoma and leptospirosis] LA - Ita MH - Human MH - Leptospirosis/*prevention & control MH - Trachoma/*prevention & control MH - Vaccination MH - *World Health Organization PT - JOURNAL ARTICLE DA - 701020 DP - 1969 Nov-Dec IS - 0021-3071 TA - Ann Sanita Pubblica PG - 911-28 CY - ITALY IP - 6 VI - 30 JC - 644 EM - 7012 PMID- 5386356 TT - L'azione sanitaria internazionale nel campo del tracoma e della leptospirosi. SO - Ann Sanita Pubblica 1969 Nov-Dec;30(6):911-28 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 70127318 AU - Drankin DI AU - Godlevskaia MV TI - [The epidemiology of swamp fever. V. Illness after consumption of contaminated food products] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases MH - Disease Reservoirs MH - English Abstract MH - *Food Microbiology MH - Human MH - *Leptospira MH - Meat MH - Milk MH - Rodentia MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 700414 DP - 1969 Nov TA - Zh Mikrobiol Epidemiol Immunobiol PG - 48-51 SB - M CY - USSR IP - 11 VI - 46 JC - Y9O EM - 7006 PMID- 5372779 CU - 89 TT - K epidemiologii vodnoi likhoradki. V. Zabolevaniia pri upotreblenii infitsirovannykh pishchevykh produktov. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Nov;46(11):48-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 70013295 AU - Colwell EJ AU - Brown JD AU - Russell PK AU - Boone SC AU - Legters LJ TI - Catino D: Investigations on acute febrile illness in American servicemen in the Mekong Delta of Vietnam. LA - Eng MH - Dengue/diagnosis MH - Diagnosis, Differential MH - Fever/*diagnosis MH - Fluorescent Antibody Technique MH - Hemagglutination Inhibition Tests MH - Hemagglutination Tests MH - Human MH - Leptospirosis/diagnosis MH - Malaria/diagnosis MH - Male MH - *Military Medicine MH - Neutralization Tests MH - Scrub Typhus/diagnosis MH - United States MH - Vietnam PT - JOURNAL ARTICLE DA - 691205 DP - 1969 Nov IS - 0026-4075 TA - Mil Med PG - 1409-14 CY - UNITED STATES IP - 12 VI - 134 JC - N1A EM - 7001 PMID- 4981388 CU - 91 SO - Mil Med 1969 Nov;134(12):1409-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 70013294 AU - Deaton JG TI - Febrile illnesses in the tropics (Vietnam). LA - Eng MH - Dengue/diagnosis MH - Diagnosis, Differential MH - Fever/*diagnosis MH - Human MH - Leptospirosis/diagnosis MH - Liver Abscess, Amebic/diagnosis MH - Malaria/diagnosis MH - Male MH - Melioidosis/diagnosis MH - *Military Medicine MH - *Tropical Medicine MH - Typhus, Epidemic Louse-Borne/diagnosis MH - United States MH - Vietnam PT - JOURNAL ARTICLE DA - 691205 DP - 1969 Nov IS - 0026-4075 TA - Mil Med PG - 1403-8 CY - UNITED STATES IP - 12 VI - 134 JC - N1A EM - 7001 PMID- 4981387 CU - 91 SO - Mil Med 1969 Nov;134(12):1403-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 70160997 AU - Freudiger U TI - [Leptospirosis in cats] LA - Ger MH - Animal MH - *Cat Diseases MH - Cats MH - English Abstract MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 700601 DP - 1969 Oct 15 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 390-2 CY - GERMANY, WEST IP - 20 VI - 82 JC - 9Q8 EM - 7007 PMID- 5393348 CU - 85 TT - Leptospireninfektionen bei Katzen. SO - Berl Munch Tierarztl Wochenschr 1969 Oct 15;82(20):390-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 71080953 AU - Trop IE AU - Grannikova SA TI - [An immunoabsorption study of strains of L. pomona isolated from farm animals in Priamur'e from 1964 to 1965] LA - Rus MH - Absorption MH - Animal MH - Antigens/*analysis MH - Cattle MH - Cattle Diseases/*microbiology MH - English Abstract MH - Leptospira/*immunology MH - Leptospirosis/microbiology/*veterinary MH - Serotyping MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 710227 DP - 1969 Oct TA - Zh Mikrobiol Epidemiol Immunobiol PG - 35-8 SB - M CY - USSR IP - 10 VI - 46 JC - Y9O EM - 7104 PMID- 5408065 CU - 89 TT - Immunoabsorbtionnoe izuchenie shtammov L. pomona, vydelennykh ot sel'skokhoziastvennykh zhivotnykh v Priamur'e v 1964-1965 gg. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Oct;46(10):35-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 71080946 AU - Samedov AD AU - Sharabchiev IuT TI - [Biosynthesis of 19S- and 7S-antibodies in rabbits with experimental leptospirosis] LA - Rus MH - Animal MH - *Antibody Formation MH - *IgG MH - *IgM MH - Leptospirosis/immunology/*prevention & control MH - Rabbits MH - Vaccination PT - JOURNAL ARTICLE DA - 710227 DP - 1969 Oct TA - Zh Mikrobiol Epidemiol Immunobiol PG - 134 SB - M CY - USSR IP - 10 VI - 46 JC - Y9O EM - 7104 PMID- 5400225 CU - 89 TT - Izuchenie biosinteza 19S- i 7S-antitel u krolikov pri eksperimental'nom leptospiroze. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Oct;46(10):134 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 70013031 AU - Shive RJ AU - Green SS AU - Evans LB AU - Garner FM TI - Leptospirosis in barbary apes (Macaca sylvana). LA - Eng MH - Animal MH - Animals, Zoo MH - District of Columbia MH - Leptospirosis/epidemiology/*veterinary MH - *Pongidae PT - JOURNAL ARTICLE DA - 691205 DP - 1969 Oct 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1176-8 SB - M CY - UNITED STATES IP - 7 VI - 155 JC - HAV EM - 7001 PMID- 5388180 CU - 88 SO - J Am Vet Med Assoc 1969 Oct 1;155(7):1176-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 70007739 AU - Mello MT de AU - Mello AM de TI - [Serological microtechnics for the diagnosis of plague, brucellosis and leptospirosis] LA - Spa MH - Bacteriological Techniques MH - Brazil MH - Brucellosis/*diagnosis MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis MH - *Microbiology MH - Plague/*diagnosis MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 691202 DP - 1969 Oct IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 300-9 CY - UNITED STATES IP - 4 VI - 67 JC - AGG EM - 7001 PMID- 4241997 CU - 92 TT - Microtecnicas serologicas para el diagnostico de peste, brucelosis y leptospirosis. SO - Bol Oficina Sanit Panam 1969 Oct;67(4):300-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 70012053 AU - Sramkova L AU - Prochazkova E AU - Novak M TI - [Alkaline leukocyte phosphatase in meningitis and meningoencephalitis] LA - Ger MH - Adolescence MH - Adult MH - Aged MH - Alkaline Phosphatase/*blood MH - Child MH - Child, Preschool MH - Female MH - Human MH - Infant MH - Leptospirosis/enzymology MH - Male MH - Meningitis/*enzymology MH - Meningoencephalitis/enzymology MH - Middle Age MH - Mumps Virus MH - Neutrophils/*enzymology MH - Tick Infestations/enzymology MH - Tuberculosis, Meningeal/enzymology PT - JOURNAL ARTICLE DA - 691205 DP - 1969 Sep 26 IS - 0025-8458 TA - Med Klin PG - 1748-52 SB - M CY - GERMANY, WEST IP - 39 VI - 64 JC - M4E EM - 7001 PMID- 5346111 TT - Alkalische leukozytenphosphatase bei Meningitis und Meningoenzyephalitis. SO - Med Klin 1969 Sep 26;64(39):1748-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [210 medline neighbors] UI - 70039667 AU - Klopper JF TI - [Leptospirosis--a discussion of 4 cases] LA - Afr MH - Adult MH - Female MH - Human MH - *Leptospirosis/diagnosis MH - Male MH - South Africa PT - JOURNAL ARTICLE DA - 700109 DP - 1969 Sep 13 IS - 0038-2469 TA - S Afr Med J PG - 1138-40 SB - M CY - SOUTH AFRICA IP - 37 VI - 43 JC - U4R EM - 7002 PMID- 5353782 TT - Leptospirose--'n bespreking van 4 gevalle. SO - S Afr Med J 1969 Sep 13;43(37):1138-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69291859 AU - VanEseltine WP AU - Jones RH AU - Gilliard FE TI - Rupture of Leptospira pomona cells by explosive decompression. LA - Eng MH - Antigens MH - *Atmospheric Pressure MH - Centrifugation, Density Gradient MH - *Leptospira/immunology MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 691031 DP - 1969 Sep IS - 0037-9727 TA - Proc Soc Exp Biol Med PG - 1446-9 SB - M CY - UNITED STATES IP - 4 VI - 131 JC - PXZ EM - 6912 PMID- 5812016 SO - Proc Soc Exp Biol Med 1969 Sep;131(4):1446-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71230745 AU - Mailloux M TI - [Leptospirosis in Equidae] LA - Fre MH - Animal MH - English Abstract MH - Horse Diseases/diagnosis/*epidemiology MH - Horses MH - Leptospirosis/diagnosis/epidemiology/*veterinary MH - Morocco MH - Weil's Disease/diagnosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 710813 DP - 1969 Sep-Oct IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 819-31 SB - M CY - FRANCE IP - 5 VI - 62 JC - C4G EM - 7110 PMID- 5409130 CU - 88 TT - Les leptospiroses des equides. SO - Bull Soc Pathol Exot Filiales 1969 Sep-Oct;62(5):819-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 70108164 AU - Sen R AU - Bhattacharji LM TI - Results of serological investigations to note the possible presence of certain communicable diseases in Sikkim. LA - Eng MH - Asia MH - Brucellosis/epidemiology MH - Communicable Diseases/*epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Rickettsia Infections/epidemiology MH - Salmonella Infections/epidemiology PT - JOURNAL ARTICLE DA - 700324 DP - 1969 Sep IS - 0019-5340 TA - Indian J Med Res PG - 1641-50 CY - INDIA IP - 9 VI - 57 JC - GJF EM - 7005 PMID- 5395669 CU - 88 SO - Indian J Med Res 1969 Sep;57(9):1641-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 70227593 AU - Elias-Jones TF TI - The bacterial zoonoses. LA - Eng MH - Animal MH - Anthrax MH - Cats MH - Cattle MH - Dogs MH - Erysipeloid MH - Fusobacterium Infections MH - Human MH - Leptospirosis MH - Listeria Infections MH - Pasteurella Infections MH - Tuberculosis MH - *Zoonoses PT - JOURNAL ARTICLE DA - 700821 DP - 1969 Sep IS - 0035-8797 TA - J R Coll Gen Pract PG - Suppl 2:18-27 CY - ENGLAND IP - 86 VI - 18 JC - JV9 EM - 7010 PMID- 5393846 CU - 85 SO - J R Coll Gen Pract 1969 Sep;18(86):Suppl 2:18-27 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70104697 AU - Genis AI AU - Tynalieva TA AU - Zapol'skikh KI AU - Vorob'eva LM TI - [Study of leptospirosis of animals in Kirghizia] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Dog Diseases/*epidemiology MH - Dogs MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/*veterinary MH - Siberia MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 700319 DP - 1969 Sep IS - 0042-4846 TA - Veterinariia PG - 34-5 CY - USSR VI - 9 JC - XCC EM - 7005 PMID- 5392427 CU - 88 TT - Izuchenie leptospiroza zhivotnykh v Kirgizii. SO - Veterinariia 1969 Sep;9:34-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 70160193 AU - Calonghi CF AU - Ielasi G AU - Pelli E TI - [Leptospriosis in the province of Brescia] LA - Ita MH - Gastroenteritis/etiology MH - Hepatitis/etiology MH - Human MH - Italy MH - Leptospirosis/complications/*epidemiology MH - Meningitis/etiology MH - Nephritis/etiology MH - Respiratory Tract Diseases/etiology MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 700528 DP - 1969 Sep IS - 0017-0321 TA - G Mal Infett Parassit PG - 725-8 CY - ITALY IP - 9 VI - 21 JC - FD7 EM - 7007 PMID- 5380533 CU - 88 TT - Leptospirosi nella provincia di Brescia. SO - G Mal Infett Parassit 1969 Sep;21(9):725-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70110135 AU - Bottura G AU - Giannuzzo E AU - Tognacca ML TI - [Study of the diffusion of leptospirosis in inhabitants of Vercelli and Biella. Results of a preliminary study of human sera] LA - Ita MH - Italy MH - Leptospirosis/*epidemiology/microbiology PT - JOURNAL ARTICLE DA - 700327 DP - 1969 Sep-Oct IS - 0017-0267 TA - G Batteriol Virol Immunol PG - 595-8 SB - M CY - ITALY IP - 9 VI - 62 JC - FA5 EM - 7005 PMID- 5370243 CU - 88 TT - Inchiesta sulla diffusione delle leitpspirosi nel Vercellese e nel Biellese. Risultati di una prima ricerca su sieri umani. SO - G Batteriol Virol Immunol 1969 Sep-Oct;62(9):595-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 70082249 AU - Henderson RJ TI - Q fever and leptospirosis in the dairy farming community and allied workers of Worcestershire. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agglutination Tests MH - Agricultural Workers' Diseases/*immunology MH - Child MH - Child, Preschool MH - Complement Fixation Tests MH - *Dairying MH - England MH - Female MH - Human MH - Infant MH - Insemination, Artificial MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Q Fever/*epidemiology PT - JOURNAL ARTICLE DA - 700225 DP - 1969 Sep IS - 0021-9746 TA - J Clin Pathol PG - 511-4 SB - A SB - M CY - ENGLAND IP - 5 VI - 22 JC - HT3 EM - 7004 PMID- 5364436 CU - 88 SO - J Clin Pathol 1969 Sep;22(5):511-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 70078131 AU - Forrester AT AU - Kranendonk O AU - Turner LH AU - Wolff JW AU - Bohlander HJ TI - Serological evidence of human leptospirosis in Kenya. LA - Eng MH - Agglutination Tests MH - Human MH - Kenya MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology MH - Male PT - JOURNAL ARTICLE DA - 700217 DP - 1969 Sep IS - 0012-835X TA - East Afr Med J PG - 497-506 CY - KENYA IP - 9 VI - 46 JC - EDG EM - 7004 PMID- 5363301 CU - 88 SO - East Afr Med J 1969 Sep;46(9):497-506 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 70078130 AU - De Geus A AU - Kranendonk O AU - Bohlander HJ TI - Clinical leptospirosis in Kwale District, Coast Province, Kenya. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Kenya MH - Leptospirosis/*epidemiology MH - Male PT - JOURNAL ARTICLE DA - 700217 DP - 1969 Sep IS - 0012-835X TA - East Afr Med J PG - 491-6 CY - KENYA IP - 9 VI - 46 JC - EDG EM - 7004 PMID- 5363300 CU - 88 SO - East Afr Med J 1969 Sep;46(9):491-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 70116320 AU - Alekseev AN AU - Chirov PA AU - Kadysheva AM AU - Sviridenko VF TI - [Preservation, multiplication and ) and unicteric leptospirosis (Leptospira grippotyphosa) by horse flies (Tabanidae) under experimental conditions] LA - Rus MH - Animal MH - *Diptera MH - English Abstract MH - *Insect Vectors MH - *Leptospira MH - *Leptospirosis MH - *Listeria monocytogenes MH - *Listeria Infections MH - Reproduction PT - JOURNAL ARTICLE DA - 700403 DP - 1969 Sep-Oct IS - 0025-8326 TA - Med Parazitol (Mosk) PG - 583-8 CY - USSR IP - 5 VI - 38 JC - M72 EM - 7005 PMID- 4984436 CU - 91 TT - Sokhrenenie, razmnozhenie i vydeleniie vo vneshniuiu sredu vozbuditelei listerioza (Listeria monoseytogenes) i bezzheltushnogo leitospiroza (Leptospira grippotyphosa) slepniami (Tabanidae) v eksperimental'nykh usloviiakh. SO - Med Parazitol (Mosk) 1969 Sep-Oct;38(5):583-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 70157021 AU - Petrov RV AU - Man'ko VM AU - Panteleev EI AU - Seslavina LS TI - [Interaction between genetically varied somatic (lymphoid) cells transplanted to lethally irradiated recipients] LA - Rus MH - Animal MH - Antibody-Producing Cells MH - Antigens MH - Bone Marrow/transplantation MH - Bone Marrow Transplantation MH - English Abstract MH - Female MH - *Genotype MH - In Vitro MH - Kidney/transplantation MH - Kidney Transplantation MH - Leptospira canicola/immunology MH - Lymph Nodes/transplantation MH - Lymphoid Tissue/*transplantation MH - Male MH - Methods MH - Mice MH - Radiation Effects MH - *Radiation Injuries, Experimental MH - Spleen/transplantation MH - Temperature MH - Time Factors MH - Transplantation, Homologous PT - JOURNAL ARTICLE DA - 700521 DP - 1969 Sep IS - 0041-3771 TA - Tsitologiia PG - 1149-61 SB - M CY - USSR IP - 9 VI - 11 JC - WGW EM - 7007 PMID- 4908722 CU - 90 TT - Vzaimodeistvie geneticheski razlichaiushchikhsia somaticheskikh (limfoidnykh) kletok, transplantirovannykh letal'no obluchennym retsipientam. SO - Tsitologiia 1969 Sep;11(9):1149-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70104698 AU - Bezborodkin NS TI - [Epizootology of swine leptospirosis] LA - Rus MH - Animal MH - Leptospirosis/*veterinary MH - Russia MH - Serodiagnosis MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 700319 DP - 1969 Sep IS - 0042-4846 TA - Veterinariia PG - 36 CY - USSR VI - 9 JC - XCC EM - 7005 PMID- 4244120 CU - 92 TT - Epizootologiia leptospiroza svinei. SO - Veterinariia 1969 Sep;9:36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71212417 AU - Kasarov LB AU - Addamiano L TI - Degradation of the phospholipids of the serum lipoproteins by leptospirae. LA - Eng MH - Animal MH - Calcium/metabolism MH - Chromatography, Thin Layer MH - Leptospira/enzymology/*metabolism MH - Lipoproteins/*blood MH - Lysophosphatidylcholines/metabolism MH - Phosphatidylcholines/metabolism MH - Phosphatidylethanolamines/metabolism MH - Phospholipids/*metabolism MH - Rabbits MH - Sphingomyelins/metabolism PT - JOURNAL ARTICLE DA - 710729 DP - 1969 Aug IS - 0022-2615 TA - J Med Microbiol PG - 243-8 SB - M CY - ENGLAND IP - 3 VI - 2 JC - J2N EM - 7109 PMID- 5405707 SO - J Med Microbiol 1969 Aug;2(3):243-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70116625 AU - Fenske E AU - Fenske G AU - Oberdoerster F TI - [Human leptospirosis acquired through swine in the GDR] LA - Ger MH - Animal MH - Germany, East MH - Human MH - Leptospirosis/*epidemiology/veterinary MH - Swine MH - Swine Diseases/*epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 700403 DP - 1969 Aug IS - 0049-8610 TA - Z Gesamte Hyg PG - 577-85 CY - GERMANY, EAST IP - 8 VI - 15 JC - XUO EM - 7005 PMID- 5371870 CU - 88 TT - Vom Schwein erworbene menschliche Leptospireninfektionen in der DDR. SO - Z Gesamte Hyg 1969 Aug;15(8):577-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 69253049 AU - Stalheim OH TI - Chemotherapy of renal leptospirosis in cattle. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - Dihydrostreptomycin Sulfate/*therapeutic use MH - Leptospirosis/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 690919 DP - 1969 Aug IS - 0002-9645 TA - Am J Vet Res PG - 1317-23 SB - M CY - UNITED STATES IP - 8 VI - 30 JC - 40C EM - 6911 PMID- 4183958 CU - 95 SO - Am J Vet Res 1969 Aug;30(8):1317-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71076985 AU - Frascarelli R TI - [Human leptospirosis in Umbria. Epidemiological and clinical observations on a case with pulmonary manifestations] LA - Ita MH - Adolescence MH - Human MH - Italy MH - Leptospirosis/*complications/epidemiology MH - Lung Diseases/*etiology MH - Male MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 710224 DP - 1969 Jul 31 IS - 0037-8771 TA - Boll Soc Ital Biol Sper PG - 961-4 SB - M CY - ITALY IP - 14 VI - 45 JC - ALS EM - 7104 PMID- 5400001 CU - 88 TT - La leptospirosi umana in Umbria. Osservazioni epidemiologiche e cliniche relative ad un caso con manifestazioni polmonari. SO - Boll Soc Ital Biol Sper 1969 Jul 31;45(14):961-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69242537 AU - Morter RL AU - Williams RD AU - Bolte H AU - Freeman MJ TI - Equine leptospirosis. LA - Eng MH - Animal MH - Eye Diseases/etiology/*veterinary MH - Horse Diseases/*immunology MH - Horses MH - Leptospirosis/*immunology MH - *Viral Vaccines PT - JOURNAL ARTICLE DA - 690908 DP - 1969 Jul 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 436-42 SB - M CY - UNITED STATES IP - 2 VI - 155 JC - HAV EM - 6910 PMID- 5816129 CU - 85 SO - J Am Vet Med Assoc 1969 Jul 15;155(2):436-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 69242538 AU - Roberts SJ TI - Comments on equine leptospirosis. LA - Eng MH - Animal MH - Endophthalmitis/etiology/*veterinary MH - Horse Diseases/*etiology MH - Horses MH - Leptospirosis/*complications PT - JOURNAL ARTICLE DA - 690908 DP - 1969 Jul 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 442-5 SB - M CY - UNITED STATES IP - 2 VI - 155 JC - HAV EM - 6910 PMID- 5306283 CU - 89 SO - J Am Vet Med Assoc 1969 Jul 15;155(2):442-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [9 medline neighbors] UI - 69282834 AU - Poppensiek GC TI - Report of the panel for the symposium on immunity to selected equine infectious diseases. Summary. LA - Eng MH - Animal MH - *Antibodies MH - Babesiosis/*immunology MH - *Bacterial Vaccines MH - Encephalomyelitis, Equine/*immunology MH - Herpesviridae Infections/immunology/*veterinary MH - Horse Diseases/*immunology MH - Horses MH - Influenza/immunology/*veterinary MH - Leptospirosis/immunology/*veterinary MH - Streptococcal Infections/immunology/*veterinary MH - Virus Diseases/*veterinary MH - Viruses, Unclassified PT - JOURNAL ARTICLE DA - 691021 DP - 1969 Jul 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 474-7 SB - M CY - UNITED STATES IP - 2 VI - 155 JC - HAV EM - 6912 PMID- 4309096 CU - 93 SO - J Am Vet Med Assoc 1969 Jul 15;155(2):474-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 69286266 AU - Stalheim OH TI - A brief review of progress in chemotherapy using leptospirosis as a model. LA - Eng MH - Animal MH - Animal Diseases/*drug therapy MH - Leptospirosis/*drug therapy PT - JOURNAL ARTICLE DA - 691023 DP - 1969 Jul IS - 0043-5465 TA - Wildl Dis PG - 213-7 CY - UNITED STATES IP - 3 VI - 5 JC - XPC EM - 6912 PMID- 5817777 CU - 85 SO - Wildl Dis 1969 Jul;5(3):213-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69286260 AU - Killinger AH AU - Hanson LE AU - Mansfield ME TI - Leptospiral vaccination of cattle exposed to infected deer. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - *Deer MH - Leptospirosis/prevention & control/*veterinary MH - Vaccination PT - JOURNAL ARTICLE DA - 691023 DP - 1969 Jul IS - 0043-5465 TA - Wildl Dis PG - 182-6 CY - UNITED STATES IP - 3 VI - 5 JC - XPC EM - 6912 PMID- 5817773 CU - 85 SO - Wildl Dis 1969 Jul;5(3):182-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69286259 AU - Andrews RD TI - Surveillance for leptospirosis in an Illinois deer herd. LA - Eng MH - Animal MH - Antibodies MH - *Deer MH - Female MH - Human MH - Illinois MH - Leptospirosis/*epidemiology/veterinary PT - JOURNAL ARTICLE DA - 691023 DP - 1969 Jul IS - 0043-5465 TA - Wildl Dis PG - 174-81 CY - UNITED STATES IP - 3 VI - 5 JC - XPC EM - 6912 PMID- 5817772 CU - 88 SO - Wildl Dis 1969 Jul;5(3):174-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69286258 AU - Diesch SL AU - McCulloch WF AU - Braun JL AU - Crawford RP Jr TI - Environmental studies on the survival of leptospires in a farm creek following a human leptospirosis outbreak in Iowa. LA - Eng MH - Human MH - Iowa MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 691023 DP - 1969 Jul IS - 0043-5465 TA - Wildl Dis PG - 166-73 CY - UNITED STATES IP - 3 VI - 5 JC - XPC EM - 6912 PMID- 5809643 CU - 88 SO - Wildl Dis 1969 Jul;5(3):166-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69286257 AU - Crawford RP Jr AU - Braun JL AU - McCulloch WF AU - Diesch SL TI - Characterization of leptospires isolated from surface waters in Iowa. LA - Eng MH - Human MH - Iowa MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 691023 DP - 1969 Jul IS - 0043-5465 TA - Wildl Dis PG - 157-65 CY - UNITED STATES IP - 3 VI - 5 JC - XPC EM - 6912 PMID- 5809642 CU - 88 SO - Wildl Dis 1969 Jul;5(3):157-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 69239539 AU - Hoeden J van den AU - Shenberg E AU - Torten M TI - A new leptospiral serotype belonging to the serogroup grippotyphosa. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antigens MH - Female MH - Human MH - Immune Sera MH - Insectivora MH - Leptospira/*classification MH - Rabbits MH - Serotyping PT - JOURNAL ARTICLE DA - 690904 DP - 1969 Jul IS - 0022-5304 TA - J Trop Med Hyg PG - 176-8 SB - M CY - ENGLAND IP - 7 VI - 72 JC - KAV EM - 6910 PMID- 5795957 SO - J Trop Med Hyg 1969 Jul;72(7):176-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70202515 AU - Gorshanova EN TI - [The properties of various Leptospira strains] LA - Rus MH - Animal MH - Antibiosis MH - *Antigens MH - Buffaloes MH - Cattle MH - Cattle Diseases/microbiology MH - English Abstract MH - Kidney/microbiology MH - Leptospira/growth & development/*immunology MH - Leptospirosis/microbiology/veterinary MH - Serotyping MH - Species Specificity MH - Swine MH - Swine Diseases/microbiology PT - JOURNAL ARTICLE DA - 700723 DP - 1969 Jul TA - Zh Mikrobiol Epidemiol Immunobiol PG - 64-7 SB - M CY - USSR IP - 7 VI - 46 JC - Y9O EM - 7009 PMID- 5393696 CU - 89 TT - Svoistva nekotorykh shtammov leptospir. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Jul;46(7):64-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 69266345 AU - Kadlcik K AU - Kramar R AU - Polednikova I AU - Tondl F AU - Vychodil J TI - [On the incidence of causative agents of some anthropozoonoses in small mammals and domestic animals] LA - Cze MH - Animal MH - Animal Diseases/*epidemiology MH - Animals, Domestic MH - Communicable Disease Control MH - Czechoslovakia MH - *Disease Reservoirs MH - Encephalitis, Tick-Borne/epidemiology MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology MH - Mammals MH - Serodiagnosis MH - Toxoplasmosis/epidemiology MH - Zoonoses/*epidemiology/etiology PT - JOURNAL ARTICLE DA - 691005 DP - 1969 Jul IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 199-204 CY - CZECHOSLOVAKIA IP - 4 VI - 18 JC - CSH EM - 6911 PMID- 4240924 CU - 92 TT - Kvysktu puvodcu nekterych antropozoonoz u drobnych savcu a domacich zvirat. SO - Cesk Epidemiol Mikrobiol Imunol 1969 Jul;18(4):199-204 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 69243813 AU - Murphy KJ TI - Exchange transfusion and albumin infusion for severe leptospiral jaundice. LA - Eng MH - Adult MH - Bilirubin/blood MH - *Exchange Transfusion, Whole Blood MH - Human MH - Infusions, Parenteral MH - Jaundice/etiology/*therapy MH - *Leptospira MH - Leptospirosis/*complications MH - Male MH - Peritoneal Dialysis MH - Serum Albumin/*therapeutic use MH - Urea/blood PT - JOURNAL ARTICLE DA - 690909 DP - 1969 Jun 21 IS - 0025-729X TA - Med J Aust PG - 1299-300 SB - M CY - AUSTRALIA IP - 25 VI - 1 JC - M26 EM - 6910 PMID- 5797609 SO - Med J Aust 1969 Jun 21;1(25):1299-300 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 69263320 AU - Engelhardt K TI - [Leptospirosis, an often unrecognized infectious disease] LA - Ger MH - Animal MH - Antibiotics/therapeutic use MH - Diagnosis, Differential MH - Hemagglutination Tests MH - Human MH - Leptospira/isolation & purification MH - *Leptospirosis/diagnosis/drug therapy/epidemiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 690930 DP - 1969 Jun 10 IS - 0300-8673 TA - Z Allgemeinmed PG - 763-8 CY - GERMANY, WEST IP - 16 VI - 45 JC - XSL EM - 6911 PMID- 5816752 CU - 88 TT - Leptospirose, eine haufig unerkannte Infektionskrankheit. SO - Z Allgemeinmed 1969 Jun 10;45(16):763-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69237250 AU - Sullivan ND AU - Stallman ND TI - The isolation of a strain of Leptospira, serotype hardjo, from cattle in Queensland. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies MH - Cattle/*immunology MH - Guinea Pigs MH - Leptospira/*isolation & purification PT - JOURNAL ARTICLE DA - 690904 DP - 1969 Jun IS - 0005-0423 TA - Aust Vet J PG - 281-3 SB - M CY - AUSTRALIA IP - 6 VI - 45 JC - 9IE EM - 6910 PMID- 5815889 CU - 85 SO - Aust Vet J 1969 Jun;45(6):281-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 69254636 AU - Nityananda K AU - Sulzer CR TI - A new leptospiral serotype in the Javanica serogroup from Ceylon. LA - Eng MH - Animal MH - *Antigens MH - Hemagglutination Tests MH - Human MH - Kidney/microbiology MH - Leptospira/*classification/*isolation & purification MH - Serotyping MH - Sri Lanka PT - JOURNAL ARTICLE DA - 690920 DP - 1969 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 207-9 SB - M CY - NETHERLANDS IP - 2 VI - 21 JC - WGJ EM - 6911 PMID- 5799577 SO - Trop Geogr Med 1969 Jun;21(2):207-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [50 medline neighbors] UI - 69254635 AU - Tedesco LF AU - Manrique G AU - Sulzer CR TI - A new leptospiral serotype in the Canicola serogroup from Argentina. LA - Eng MH - Animal MH - *Antigens MH - Argentina MH - Cattle MH - Hemagglutination Tests MH - Leptospira canicola/*classification/immunology/*isolation & purification MH - Serotyping PT - JOURNAL ARTICLE DA - 690920 DP - 1969 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 203-6 SB - M CY - NETHERLANDS IP - 2 VI - 21 JC - WGJ EM - 6911 PMID- 5799576 SO - Trop Geogr Med 1969 Jun;21(2):203-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69254634 AU - Wolff JW AU - Bohlander HJ TI - A survey for leptospiral antibodies in sera from the Bushland population of Surinam. LA - Eng MH - Adult MH - Age Factors MH - Antibodies/*isolation & purification MH - *Blacks MH - Child, Preschool MH - Female MH - Health Surveys MH - Hemagglutination Tests MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology MH - Male MH - Serotyping MH - Suriname PT - JOURNAL ARTICLE DA - 690920 DP - 1969 Jun IS - 0041-3232 TA - Trop Geogr Med PG - 199-202 SB - M CY - NETHERLANDS IP - 2 VI - 21 JC - WGJ EM - 6911 PMID- 5799575 CU - 88 SO - Trop Geogr Med 1969 Jun;21(2):199-202 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [195 medline neighbors] UI - 69215556 AU - Jenkin HM AU - Anderson LE AU - Holman RT AU - Ismail IA AU - Gunstone FD TI - Effect of isomeric cis-octadecenoic acids on the growth of Leptospira interrogans serotype patoc. LA - Eng MH - Culture Media MH - Leptospira/*drug effects/growth & development MH - Oleic Acids/*pharmacology MH - Stereoisomerism MH - Surface-Active Agents/pharmacology PT - JOURNAL ARTICLE DA - 690807 DP - 1969 Jun IS - 0021-9193 TA - J Bacteriol PG - 1026-9 SB - M CY - UNITED STATES IP - 3 VI - 98 JC - HH3 EM - 6909 PMID- 5788693 CU - 96 SO - J Bacteriol 1969 Jun;98(3):1026-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71002600 AU - Knorre G von TI - [Present incidence of human leptospirosis in the German Democratic Republic] LA - Ger MH - Animal MH - English Abstract MH - Germany, East MH - Human MH - Leptospira/pathogenicity MH - Leptospira canicola/pathogenicity MH - Leptospira interrogans/pathogenicity MH - Leptospirosis/*epidemiology MH - Weil's Disease/epidemiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 701120 DP - 1969 Jun 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 401-6 CY - GERMANY, EAST IP - 11 VI - 24 JC - NGV EM - 7101 PMID- 5407746 CU - 88 TT - Die aktuelle Situation der Leptospirose des Menschen in der DDR. SO - Monatsh Veterinarmed 1969 Jun 1;24(11):401-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70051798 AU - Soloshenko IZ AU - Petrov EM AU - Shorokhov VV AU - Drogun AG AU - Grigor'ev VG AU - Anokhin II AU - Kareva EP AU - Tarabrina AP TI - [Sources of infection of animals with leptospirosis] LA - Rus MH - Animal MH - Animal Diseases/*etiology MH - Cattle MH - Cattle Diseases/etiology MH - Disease Reservoirs/*veterinary MH - Female MH - Horse Diseases/etiology MH - Horses MH - Leptospirosis/*veterinary MH - Mice MH - Rats MH - Sheep MH - Sheep Diseases/etiology MH - Swine MH - Swine Diseases/etiology PT - JOURNAL ARTICLE DA - 700119 DP - 1969 Jun IS - 0042-4846 TA - Veterinariia PG - 39-42 CY - USSR IP - 7 VI - 46 JC - XCC EM - 7003 PMID- 5389986 CU - 85 TT - Istochniki zarazheniia zhivotnykh leptospirozom. SO - Veterinariia 1969 Jun;46(7):39-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70051796 AU - Kirpichev AF TI - [Isolation of leptospira cultures from slaughtered animals] LA - Rus MH - Abattoirs MH - Agriculture MH - Animal MH - Leptospira/*isolation & purification MH - Leptospirosis/*veterinary MH - Rabbits MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 700119 DP - 1969 Jun IS - 0042-4846 TA - Veterinariia PG - 36-7 CY - USSR IP - 7 VI - 46 JC - XCC EM - 7003 PMID- 5389985 CU - 85 TT - Vydelenie kul'tur leptospir ot uboinykh zhivotnykh. SO - Veterinariia 1969 Jun;46(7):36-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70078859 AU - Manew C TI - [A double-layer nutrient medium for the maintenance of leptospira strains] LA - Ger MH - Agar MH - *Culture Media MH - English Abstract MH - Leptospira/*growth & development MH - Methods MH - Serotyping PT - JOURNAL ARTICLE DA - 700217 DP - 1969 Jun TA - Zentralbl Bakteriol [Orig] PG - 216-20 SB - M CY - GERMANY, WEST IP - 2 VI - 210 JC - Y4Y EM - 7004 PMID- 5363463 CU - 90 TT - Ein zweischichtiger Nahrboden fur die Leptospirenstammhaltung. SO - Zentralbl Bakteriol [Orig] 1969 Jun;210(2):216-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 70051795 AU - Glushkov AA TI - [Hemotoxins and leptospiral lipase] LA - Rus MH - Animal MH - In Vitro MH - Leptospira/*metabolism MH - Lipase/*biosynthesis MH - Rabbits MH - Sheep MH - Swine MH - Toxins/*biosynthesis PT - JOURNAL ARTICLE DA - 700119 DP - 1969 Jun IS - 0042-4846 TA - Veterinariia PG - 32-6 CY - USSR IP - 7 VI - 46 JC - XCC EM - 7003 PMID- 5355821 TT - Gemotoksiny i lipaza leptospir. SO - Veterinariia 1969 Jun;46(7):32-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 71078560 AU - Sturdza N AU - Iancu L AU - Ciurea C AU - Niculescu M AU - Borsai L AU - Lola C TI - Indirect immunofluorescence technique as compared with other methods for investigating the renal carrier state of leptospira in pigs. LA - Eng MH - Animal MH - Carrier State/*diagnosis MH - *Fluorescent Antibody Technique MH - Guinea Pigs MH - Leptospirosis/diagnosis/*veterinary MH - Swine MH - Swine Diseases/*diagnosis MH - Weil's Disease/diagnosis/*veterinary PT - JOURNAL ARTICLE DA - 710224 DP - 1969 Jun-Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 319-28 CY - ROMANIA IP - 2 VI - 28 JC - 8EM EM - 7104 PMID- 4923818 CU - 90 SO - Arch Roum Pathol Exp Microbiol 1969 Jun-Sep;28(2):319-28 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 69261305 AU - Vance SF 3d TI - Diagnostic laboratory medicine--leptospirosis--methods in the laboratory diagnosis. LA - Eng MH - Biopsy MH - Fluorescent Antibody Technique MH - Human MH - Leptospirosis/*diagnosis MH - Methods MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 690930 DP - 1969 Jun TA - Va Med Mon PG - 335-7 CY - UNITED STATES IP - 6 VI - 96 JC - X6V EM - 6911 PMID- 4895706 CU - 90 SO - Va Med Mon 1969 Jun;96(6):335-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69212586 AU - Ovcinnikov NM AU - Delektorskij VV TI - Further studies of the morphology of Treponema pallidum under the electron microscope. LA - Eng MH - Bacteriological Techniques MH - Borrelia/cytology MH - Cell Division MH - Human MH - Leptospira/cytology MH - Male MH - Microscopy, Electron MH - Orchitis/microbiology MH - Organoids MH - Ribosomes MH - Time Factors MH - Treponema pallidum/*cytology PT - JOURNAL ARTICLE DA - 690805 DP - 1969 Jun IS - 0007-134X TA - Br J Vener Dis PG - 87-116 SB - M CY - ENGLAND IP - 2 VI - 45 JC - B40 EM - 6909 PMID- 4892124 CU - 90 SO - Br J Vener Dis 1969 Jun;45(2):87-116 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70101684 AU - Dragomir AV AU - Korolev VM AU - Matveeva AA TI - [The epizootiology of leptospirosis of animals] LA - Rus MH - Animal MH - Animal Diseases/*epidemiology MH - Leptospirosis/*veterinary MH - Moldova PT - JOURNAL ARTICLE DA - 700314 DP - 1969 Jun IS - 0042-4846 TA - Veterinariia PG - 41-2 CY - USSR IP - 6 VI - 46 JC - XCC EM - 7005 PMID- 4244036 CU - 92 TT - Epizootologiia leptospiroza zhivotnykh. SO - Veterinariia 1969 Jun;46(6):41-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 69208756 AU - Odehnal P AU - Horak J AU - Sutory K AU - Fantova Z TI - [Epidemic of leptospirosis grippotyphosa in the Zdar district in 1966] LA - Cze MH - Adolescence MH - Adult MH - Child MH - Czechoslovakia MH - English Abstract MH - Female MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/complications/diagnosis/drug therapy/*epidemiology MH - Male MH - Tetracycline/therapeutic use PT - JOURNAL ARTICLE DA - 690803 DP - 1969 May 23 IS - 0008-7335 TA - Cas Lek Cesk PG - 666-73 CY - CZECHOSLOVAKIA IP - 22 VI - 108 JC - CPY EM - 6909 PMID- 5786016 CU - 88 TT - Epidemie onemocnemi leptospirosis grippotyphosa na zdarskem okrese v roce 1966. SO - Cas Lek Cesk 1969 May 23;108(22):666-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [108 medline neighbors] UI - 69164936 AU - Peters D AU - Muller G TI - The Marburg agent and structures associated with leptospira. LA - Eng MH - *Arboviruses MH - Leptospira/*cytology MH - Microscopy, Electron MH - Staining MH - *Viruses, Unclassified PT - JOURNAL ARTICLE DA - 690604 DP - 1969 May 3 IS - 0140-6736 TA - Lancet PG - 923-5 SB - A SB - M CY - ENGLAND IP - 601 VI - 1 JC - L0S EM - 6907 PMID- 4180901 CU - 95 SO - Lancet 1969 May 3;1(601):923-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 69288112 AU - Wegmann T TI - [Zoonoses as problems of medicine] LA - Ger MH - Animal MH - Echinococcosis/epidemiology MH - English Abstract MH - Human MH - Leptospirosis/epidemiology MH - Ornithosis/epidemiology MH - Rickettsia Infections/epidemiology MH - Toxoplasmosis/epidemiology MH - Tularemia/epidemiology MH - *Zoonoses PT - JOURNAL ARTICLE DA - 691025 DP - 1969 May IS - 0036-7281 TA - Schweiz Arch Tierheilkd PG - 260-70 CY - SWITZERLAND IP - 5 VI - 111 JC - UE5 EM - 6912 PMID- 5820320 CU - 88 TT - Zoonosen als Probleme fur die Medizin. SO - Schweiz Arch Tierheilkd 1969 May;111(5):260-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69166366 AU - Murphy JC AU - Jensen R TI - Experimental pathogenesis of leptospiral abortion in cattle. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Cattle MH - *Cattle Diseases MH - Female MH - Leptospirosis/complications/*veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 690605 DP - 1969 May IS - 0002-9645 TA - Am J Vet Res PG - 703-13 SB - M CY - UNITED STATES IP - 5 VI - 30 JC - 40C EM - 6907 PMID- 5813667 CU - 85 SO - Am J Vet Res 1969 May;30(5):703-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69254791 AU - Anan'in VV AU - Kiktenko VS TI - [Classification of strains of leptospira of the pomona serologic group] LA - Rus MH - Absorption MH - Agglutination Tests MH - *Antigens MH - English Abstract MH - Leptospira/*classification/isolation & purification MH - Serotyping MH - USSR PT - JOURNAL ARTICLE DA - 690920 DP - 1969 May TA - Zh Mikrobiol Epidemiol Immunobiol PG - 113-8 SB - M CY - USSR IP - 5 VI - 46 JC - Y9O EM - 6911 PMID- 5799592 CU - 89 TT - Klassifikatsiia shtammov leptospir serologicheskoi gruppy pomona. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 May;46(5):113-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69204056 AU - Haapala DK AU - Rogul M AU - Evans LB AU - Alexander AD TI - Deoxyribonucleic acid base composition and homology studies of Leptospira. LA - Eng MH - Adenine/metabolism MH - Agglutination Tests MH - Chemistry, Physical MH - Cytosine/analysis MH - DNA, Bacterial/*analysis MH - Guanine/analysis MH - Leptospira/*classification/metabolism MH - Nucleic Acid Denaturation MH - Serotyping MH - Tritium PT - JOURNAL ARTICLE DA - 690730 DP - 1969 May IS - 0021-9193 TA - J Bacteriol PG - 421-8 SB - M CY - UNITED STATES IP - 2 VI - 98 JC - HH3 EM - 6909 PMID- 5784202 SO - J Bacteriol 1969 May;98(2):421-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71007429 AU - Beer J AU - Schumm HR AU - Horsch F AU - Frederich W AU - Konig H AU - Hahlweg B AU - Wendt K AU - Klahn J TI - [Attempts to erradicate Leptospira tarassovi (syn. hyos) infection in large pig breeding stocks] LA - Ger MH - Abortion, Veterinary/prevention & control MH - Animal MH - Breeding MH - English Abstract MH - Female MH - Leptospirosis/prevention & control/*veterinary MH - Pregnancy MH - Sterilization MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 701202 DP - 1969 May 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 327-33 CY - GERMANY, EAST IP - 9 VI - 24 JC - NGV EM - 7101 PMID- 5407785 CU - 85 TT - Versuche zur Tilgung der Leptospira-tarassovi(syn. hyos)-Infektion in grosseren Schweinezuchtbestanden. SO - Monatsh Veterinarmed 1969 May 1;24(9):327-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 70079066 AU - Mailloux M TI - [Caprine and ovine leptospirosis] LA - Fre MH - Abortion/veterinary MH - Agglutination Tests MH - Animal MH - English Abstract MH - Female MH - *Goats MH - Hematuria/veterinary MH - Jaundice/veterinary MH - Leptospirosis/epidemiology/pathology/*veterinary MH - Morocco MH - Pregnancy MH - Serodiagnosis MH - Serotyping MH - Sheep MH - *Sheep Diseases PT - JOURNAL ARTICLE DA - 700217 DP - 1969 May-Jun IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 508-16 SB - M CY - FRANCE IP - 3 VI - 62 JC - C4G EM - 7004 PMID- 5395509 CU - 88 TT - Les leptospiroses ovines et caprines. SO - Bull Soc Pathol Exot Filiales 1969 May-Jun;62(3):508-16 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 70079065 AU - Gauthier R AU - Brochier A AU - Lavallee M AU - Comby F AU - Lataste-Dorolle C TI - [New contributions to the study of leptospirosis in Reunion. I. Study of 70 cases, 18 of which fatal: clinical and biological aspects. Physiopathological considerations] LA - Fre MH - Age Factors MH - Agglutination Tests MH - Albuminuria/pathology MH - Anemia/pathology MH - Anuria/pathology MH - Blood Coagulation Disorders MH - English Abstract MH - Female MH - Hemorrhage/pathology MH - Hemostasis MH - Hepatomegaly/pathology MH - Human MH - Hydrogen-Ion Concentration MH - Indian Ocean Islands MH - Jaundice/pathology MH - Leptospira interrogans/isolation & purification/*pathogenicity MH - *Leptospirosis/epidemiology/pathology/physiopathology MH - Male MH - Seasons/adverse effects MH - Sex Factors MH - Uric Acid/metabolism MH - Water-Electrolyte Balance PT - JOURNAL ARTICLE DA - 700217 DP - 1969 May-Jun IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 493-508 SB - M CY - FRANCE IP - 3 VI - 62 JC - C4G EM - 7004 PMID- 5395508 CU - 88 TT - Nouvelles contributions a l'etude des leptospiroses a la reunion. I. Etude de 70 cas dont 18 mortels: aspects cliniques et biologiques. Considerations physio-pathologiques. SO - Bull Soc Pathol Exot Filiales 1969 May-Jun;62(3):493-508 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70262629 AU - Man'ko VM AU - Sidorovich IG AU - Zhabina MI AU - Petrov RV TI - [Loss of secondary immune response by antibody-forming cells cultured in vivo] LA - Rus MH - Animal MH - *Antibody Formation MH - Antibody-Producing Cells MH - *Antigens MH - English Abstract MH - Leptospira canicola/*immunology MH - Male MH - Mice MH - Spleen/immunology PT - JOURNAL ARTICLE DA - 701002 DP - 1969 May-Jun TA - Zh Obshch Biol PG - 324-31 CY - USSR IP - 3 VI - 30 JC - YA8 EM - 7011 PMID- 5394052 CU - 89 TT - Utrata vtorichnogo immunologicheskogo otveta antiteloobrazuiushchimi kletkami v kul'ture in vivo. SO - Zh Obshch Biol 1969 May-Jun;30(3):324-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 69297455 AU - Kasarov LB AU - Addamiano L TI - Metabolism of the lipoproteins of serum by leptospires: degradation of the triglycerides. LA - Eng MH - Animal MH - Blood Protein Electrophoresis MH - Blood Proteins/metabolism MH - Chromatography, Thin Layer MH - Fatty Acids, Nonesterified/metabolism MH - Leptospira/enzymology/*metabolism MH - Lipase/analysis MH - Lipids/blood MH - Lipoproteins/*metabolism MH - Rabbits MH - Triglycerides/*metabolism PT - JOURNAL ARTICLE DA - 691105 DP - 1969 May IS - 0022-2615 TA - J Med Microbiol PG - 165-8 SB - M CY - ENGLAND IP - 2 VI - 2 JC - J2N EM - 6912 PMID- 5387688 CU - 85 SO - J Med Microbiol 1969 May;2(2):165-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 70100381 AU - Pupkevich-Diamant IaS TI - [Aldolase and transaminase activity in leptospirosis] LA - Rus MH - Aminotransferases/*blood MH - Female MH - Fructosediphosphate Aldolase/*blood MH - Human MH - Leptospirosis/*blood MH - Male PT - JOURNAL ARTICLE DA - 700314 DP - 1969 May IS - 0023-2149 TA - Klin Med (Mosk) PG - 62-4 CY - USSR IP - 5 VI - 47 JC - KW2 EM - 7005 PMID- 5367592 TT - Al'dolaznaia i transaminaznaia aktivnost' pri leptospiroznykh zabolevaniiakh. SO - Klin Med (Mosk) 1969 May;47(5):62-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 70100380 AU - Khaimzon BI TI - [The clinical picture of the meningeal form of nonicteric leptospirosis] LA - Rus MH - Human MH - Leptospirosis/*complications MH - Meningitis/*etiology PT - JOURNAL ARTICLE DA - 700314 DP - 1969 May IS - 0023-2149 TA - Klin Med (Mosk) PG - 60-2 CY - USSR IP - 5 VI - 47 JC - KW2 EM - 7005 PMID- 5367591 TT - Klinika nemingeal'noi formy bezzheltushnogo leptospiroza. SO - Klin Med (Mosk) 1969 May;47(5):60-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 70006587 AU - Vita A AU - Brauner E AU - Mihul V AU - Baltiev A AU - Dimitriu S AU - Turcu T AU - Cercel I AU - Petrovanu I TI - [Electroencephalographic changes in meningitis with clear cerebrospinal fluid] LA - Rum MH - Brain/physiopathology MH - Electroencephalography MH - English Abstract MH - Human MH - Influenza/complications MH - Leptospirosis/complications MH - *Meningitis MH - *Meningitis, Viral MH - *Meningoencephalitis MH - Mumps/complications MH - *Tuberculosis, Meningeal PT - JOURNAL ARTICLE DA - 691201 DP - 1969 May-Jun IS - 0028-386X TA - Neurol Psihiatr Neurochir PG - 237-43 CY - ROMANIA IP - 3 VI - 14 JC - NYQ EM - 7001 PMID- 5343897 TT - Modificari electroencefalografice in meningitele cu lichid cefalorahidian clar. SO - Neurol Psihiatr Neurochir 1969 May-Jun;14(3):237-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69228695 AU - Twigg GI AU - Cuerden CM AU - Hughes DM AU - Medhurst P TI - The leptospirosis reservoir in British wild mammals. LA - Eng MH - Animal MH - *Animal Diseases MH - Artiodactyla MH - Carnivora MH - Cattle MH - *Disease Reservoirs MH - Environment MH - Great Britain MH - Horse Diseases MH - Horses MH - Insectivora MH - Kidney/microbiology MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/veterinary MH - Mice MH - Rabbits MH - Rats MH - Rodentia MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 690821 DP - 1969 Apr 26 IS - 0042-4900 TA - Vet Rec PG - 424-6 SB - M CY - ENGLAND IP - 17 VI - 84 JC - XBS EM - 6910 PMID- 5815472 CU - 88 SO - Vet Rec 1969 Apr 26;84(17):424-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69242153 AU - Kingscote BF TI - Leptospirosis survey in a white-tailed deer herd in Ontario: comparative use of fluid and paper disc-absorbed blood. LA - Eng MH - Agglutination Tests MH - Animal MH - *Deer MH - Leptospirosis/blood/*epidemiology MH - Ontario PT - JOURNAL ARTICLE DA - 690905 DP - 1969 Apr IS - 0043-5465 TA - Wildl Dis PG - 68-72 CY - UNITED STATES IP - 2 VI - 5 JC - XPC EM - 6910 PMID- 5816101 CU - 88 SO - Wildl Dis 1969 Apr;5(2):68-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 69209745 AU - Osechinsky IV AU - Mekler LB AU - Petrov RV AU - Mityushin VM TI - The use of iodinated antibodies for the location of antigens on the surface of Leptospira canicola by electron microscopy. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antibodies MH - Haptens/*analysis MH - Histocytochemistry MH - IgG MH - IgM MH - Immunochemistry MH - In Vitro MH - Iodine MH - Leptospira canicola/*immunology MH - Mice MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 690803 DP - 1969 Apr IS - 0019-2805 TA - Immunology PG - 427-31 SB - M CY - ENGLAND IP - 4 VI - 16 JC - GH7 EM - 6909 PMID- 5786395 SO - Immunology 1969 Apr;16(4):427-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69155400 AU - Sheehy TW TI - On enteric diseases among our troops in Vietnam. LA - Eng MH - Fever/epidemiology MH - Human MH - Intestinal Diseases/*epidemiology MH - Leptospirosis/*epidemiology MH - Malaria/*epidemiology MH - Male MH - *Military Medicine MH - United States MH - Vietnam PT - JOURNAL ARTICLE DA - 690520 DP - 1969 Apr IS - 0016-5085 TA - Gastroenterology PG - 820 SB - A SB - M CY - UNITED STATES IP - 4 VI - 56 JC - FH3 EM - 6907 PMID- 5777479 CU - 88 SO - Gastroenterology 1969 Apr;56(4):820 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69155399 AU - Mitchell MH TI - On enteric disease among our troops in Vietnam. LA - Eng MH - Fever/epidemiology MH - Human MH - Intestinal Diseases/*epidemiology MH - Leptospirosis/*epidemiology MH - Malaria/*epidemiology MH - Male MH - *Military Medicine MH - United States MH - Vietnam PT - JOURNAL ARTICLE DA - 690520 DP - 1969 Apr IS - 0016-5085 TA - Gastroenterology PG - 819 SB - A SB - M CY - UNITED STATES IP - 4 VI - 56 JC - FH3 EM - 6907 PMID- 5777478 CU - 88 SO - Gastroenterology 1969 Apr;56(4):819 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 70131955 AU - Poddubnyi VA AU - Nikitiuk NP AU - Barantsev IM TI - [Non-icteric leptospirosis associated with water contaminated by muskrats] LA - Rus MH - Animal MH - *Disease Outbreaks MH - *Disease Vectors MH - English Abstract MH - Human MH - Leptospirosis/*etiology MH - *Rodentia MH - USSR MH - *Water Supply PT - JOURNAL ARTICLE DA - 700420 DP - 1969 Apr IS - 0049-6804 TA - Vrach Delo PG - 123-4 CY - USSR VI - 4 JC - XLS EM - 7006 PMID- 5392893 CU - 85 TT - Zabolevaniia bezzheltushnym leptospirozom, sviazannye s zarazheniem vody ondatrami. SO - Vrach Delo 1969 Apr;4:123-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [87 medline neighbors] UI - 69209795 AU - Nauman RK AU - Holt SC AU - Cox CD TI - Purification, ultrastructure, and composition of axial filaments from Leptospira. LA - Eng MH - Amino Acids/analysis MH - Bacterial Proteins/analysis MH - Centrifugation, Density Gradient MH - Electrophoresis, Disc MH - Flagella/analysis MH - Freeze Etching MH - Histological Techniques MH - Leptospira/analysis/*cytology/physiology MH - Microscopy, Electron MH - Models, Structural MH - Movement MH - Organoids PT - JOURNAL ARTICLE DA - 690803 DP - 1969 Apr IS - 0021-9193 TA - J Bacteriol PG - 264-80 SB - M CY - UNITED STATES IP - 1 VI - 98 JC - HH3 EM - 6909 PMID- 4891807 CU - 90 SO - J Bacteriol 1969 Apr;98(1):264-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 69220050 AU - Trutnev BD AU - Sekunova AN TI - [The spectrum of antibodies in equine and bovine gamma-globulin] LA - Rus MH - Agglutination Tests MH - Animal MH - Antibodies/*analysis MH - Cattle MH - Dysentery, Bacillary/*immunology MH - Encephalomyelitis, Equine/*immunology MH - English Abstract MH - Gamma-Globulins/*analysis MH - Hemagglutination Tests MH - Horses MH - Immune Sera/*analysis MH - Leptospirosis/*immunology MH - Rabies/*immunology MH - Salmonella Infections/*immunology PT - JOURNAL ARTICLE DA - 690808 DP - 1969 Apr TA - Zh Mikrobiol Epidemiol Immunobiol PG - 41-3 SB - M CY - USSR IP - 4 VI - 46 JC - Y9O EM - 6909 PMID- 4182940 CU - 95 TT - Spektr antitel v loshadinykh i volov'ikh gamma-globulinakh. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Apr;46(4):41-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69204683 AU - Lavrova MIa TI - [On the limits and structure of the nosoareal of leptospirosis in the USSR] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Human MH - Leptospirosis/*epidemiology MH - Swine MH - Swine Diseases/*epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 690730 DP - 1969 Mar TA - Zh Mikrobiol Epidemiol Immunobiol PG - 82-7 SB - M CY - USSR IP - 3 VI - 46 JC - Y9O EM - 6909 PMID- 5814715 CU - 89 TT - O granitsakh i strukture nozoareala leptospirozov v SSSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Mar;46(3):82-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 69215993 AU - Szewczyk Z AU - Ratajczak T TI - [A severe case of leptospirosis with vascular lesions of the skin and mucosa] LA - Pol MH - Adult MH - Case Report MH - Human MH - Kidney Failure, Acute/etiology MH - Leg Dermatoses/*etiology MH - Leptospirosis/*complications MH - Male MH - Necrosis/etiology MH - Pneumonia/etiology MH - *Skin Manifestations MH - Vascular Diseases/*etiology PT - JOURNAL ARTICLE DA - 690807 DP - 1969 Mar 1 IS - 0043-5147 TA - Wiad Lek PG - 465-8 CY - POLAND IP - 5 VI - 22 JC - XOA EM - 6909 PMID- 5788856 TT - Ciezki przypadek leptospirozy ze zmianami w naczyniach skory i blon sluzowych. SO - Wiad Lek 1969 Mar 1;22(5):465-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [160 medline neighbors] UI - 69177641 AU - Livermore BP AU - Johnson RC AU - Jenkin HM TI - Isolation of an unusual positional isomer of hexadecenoic acid from a parasitic leptospire. LA - Eng MH - Chromatography, Gas MH - Chromatography, Thin Layer MH - Fatty Acids/*analysis MH - Leptospira/*analysis MH - Stereoisomerism PT - JOURNAL ARTICLE DA - 690624 DP - 1969 Mar IS - 0024-4201 TA - Lipids PG - 166-7 SB - M CY - UNITED STATES IP - 2 VI - 4 JC - L73 EM - 6908 PMID- 5782078 CU - 96 SO - Lipids 1969 Mar;4(2):166-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69169525 AU - Stern N AU - Shenberg E AU - Tietz A TI - Studies on the metabolism of fatty acids in Leptospira: the biosynthesis of delta 9- and delta 11-monounsaturated acids. LA - Eng MH - Acetates/*metabolism MH - Bacterial Proteins/biosynthesis MH - Biotin/pharmacology MH - Carbon Isotopes MH - Chromatography, Gas MH - Culture Media MH - Depression, Chemical MH - Dicarboxylic Acids/analysis MH - Fatty Acids/analysis/*biosynthesis/isolation & purification/metabolism MH - Hydrogen-Ion Concentration MH - Leptospira canicola/*metabolism MH - Lipids/biosynthesis/isolation & purification MH - Oleic Acids/metabolism MH - Palmitic Acids/metabolism MH - Phosphatidylethanolamines/*biosynthesis MH - Phospholipids/biosynthesis MH - Stearic Acids/metabolism MH - Surface-Active Agents/metabolism MH - Triglycerides/*biosynthesis PT - JOURNAL ARTICLE DA - 690609 DP - 1969 Mar IS - 0014-2956 TA - Eur J Biochem PG - 101-8 SB - M CY - GERMANY, WEST IP - 1 VI - 8 JC - EMZ EM - 6907 PMID- 5781264 SO - Eur J Biochem 1969 Mar;8(1):101-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 69166462 AU - Berg RN AU - Green SS AU - Goldberg HS AU - Blenden DC TI - Density-gradient and chromatographic fraction of leptospiral lipase. LA - Eng MH - Bacterial Proteins/analysis MH - Centrifugation, Density Gradient MH - Chromatography MH - Electrophoresis, Disc MH - Leptospira/*enzymology MH - Lipase/*analysis/metabolism PT - JOURNAL ARTICLE DA - 690605 DP - 1969 Mar IS - 0003-6919 TA - Appl Microbiol PG - 467-72 SB - M CY - UNITED STATES IP - 3 VI - 17 JC - 6K0 EM - 6907 PMID- 5780402 SO - Appl Microbiol 1969 Mar;17(3):467-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 69151498 AU - Baseman JB AU - Cox CD TI - Intermediate energy metabolism of Leptospira. LA - Eng MH - Cell-Free System MH - Citric Acid Cycle MH - Dyes/pharmacology MH - Glycolysis MH - Leptospira/enzymology/*metabolism MH - Manometry MH - Oleic Acids/metabolism/pharmacology MH - Oxygen Consumption MH - Water Microbiology PT - JOURNAL ARTICLE DA - 690515 DP - 1969 Mar IS - 0021-9193 TA - J Bacteriol PG - 992-1000 SB - M CY - UNITED STATES IP - 3 VI - 97 JC - HH3 EM - 6907 PMID- 5776541 CU - 90 SO - J Bacteriol 1969 Mar;97(3):992-1000 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 69151415 AU - Baseman JB AU - Cox CD TI - Terminal electron transport in Leptospira. LA - Eng MH - Azides/pharmacology MH - Cell-Free System MH - Cyanides/pharmacology MH - Cytochromes/analysis MH - *Electron Transport MH - Leptospira/enzymology/*metabolism MH - Manometry MH - Oxygen Consumption/drug effects MH - Spectrophotometry PT - JOURNAL ARTICLE DA - 690515 DP - 1969 Mar IS - 0021-9193 TA - J Bacteriol PG - 1001-4 SB - M CY - UNITED STATES IP - 3 VI - 97 JC - HH3 EM - 6907 PMID- 5776514 CU - 90 SO - J Bacteriol 1969 Mar;97(3):1001-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 69189047 AU - Torney HL AU - Bordt DE TI - Viability quantitation of leptospires after rapid and controlled rate freezing. LA - Eng MH - Animal MH - Cattle MH - *Freezing MH - Hamsters MH - Leptospira/*growth & development MH - Methods MH - Nitrogen MH - *Preservation, Biological MH - Rabbits MH - Serotyping MH - Species Specificity MH - Time Factors MH - Tissue Culture MH - *Virulence PT - JOURNAL ARTICLE DA - 690703 DP - 1969 Mar-Apr IS - 0011-2240 TA - Cryobiology PG - 352-4 SB - M CY - UNITED STATES IP - 5 VI - 5 JC - DT3 EM - 6908 PMID- 5770749 CU - 90 SO - Cryobiology 1969 Mar-Apr;5(5):352-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70183849 AU - Kurakina TA TI - [Leptospirosis in animals in the L'vov region] LA - Rus MH - Animal MH - Animal Diseases/*epidemiology MH - Cattle MH - Cattle Diseases/microbiology MH - Dog Diseases/microbiology MH - Dogs MH - Horse Diseases/microbiology MH - Horses MH - Leptospira/isolation & purification MH - Leptospirosis/*veterinary MH - Rats MH - Sheep MH - Sheep Diseases/microbiology MH - Swine MH - Swine Diseases/microbiology MH - Ukraine PT - JOURNAL ARTICLE DA - 700701 DP - 1969 Mar IS - 0042-4846 TA - Veterinariia PG - 36 CY - USSR IP - 3 VI - 46 JC - XCC EM - 7008 PMID- 5393557 CU - 88 TT - Leptospiroz u zhivotnykh na L'vovshchine. SO - Veterinariia 1969 Mar;46(3):36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 70159308 AU - Stangalini A AU - Gagliardi B AU - Fumagalli E TI - [The rapid slide agglutination test in serodiagnosis of leptospirosis. Preliminary checking of 350 patients hospitalized in the Ospedale Maggiore di Novara (1966-1967)] LA - Ita MH - *Agglutination Tests MH - Human MH - Leptospirosis/*diagnosis MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 700527 DP - 1969 Mar IS - 0017-0321 TA - G Mal Infett Parassit PG - 171-3 CY - ITALY IP - 3 VI - 21 JC - FD7 EM - 7007 PMID- 5380336 TT - Il test di agglutinazione rapida su vetrino nella sierodiagnosi di leptospirosi. Primo controllo in 350 pazienti ricoverati presso l'Ospedale Maggiore di Novara (1966-1967) SO - G Mal Infett Parassit 1969 Mar;21(3):171-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69203250 AU - Johnson RC AU - Harris VG AU - Walby JK TI - Characterization of leptospires according to fatty acid requirements. LA - Eng MH - Bacteriological Techniques MH - Fatty Acids/*metabolism MH - Growth MH - Leptospira/*classification/metabolism MH - Oleic Acids/metabolism MH - Palmitic Acids/metabolism MH - Parasites MH - Stearic Acids/metabolism MH - Temperature MH - Tissue Culture PT - JOURNAL ARTICLE DA - 690730 DP - 1969 Mar IS - 0022-1287 TA - J Gen Microbiol PG - 399-407 SB - M CY - ENGLAND IP - 3 VI - 55 JC - I87 EM - 6909 PMID- 4891171 CU - 90 SO - J Gen Microbiol 1969 Mar;55(3):399-407 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71134644 AU - Mailloux M TI - [Serodiagnosis of leptospirosis] LA - Fre MH - Agglutination Tests MH - Animal MH - Human MH - Leptospirosis/*diagnosis MH - *Serodiagnosis PT - JOURNAL ARTICLE PT - REVIEW DA - 710426 DP - 1969 Mar-Apr IS - 0006-3266 TA - Biol Med (Paris) PG - 89-132 CY - FRANCE IP - 2 VI - 58 JC - BB0 EM - 7106 RF - 238 PMID- 4251239 CU - 92 TT - A propos des sero-diagnostics des leptospiroses. SO - Biol Med (Paris) 1969 Mar-Apr;58(2):89-132 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 70183850 AU - Chepurov KP AU - Pruss OG TI - [Therapeutic-preventive properties of gamma globulin in leptospirosis in swine] LA - Rus MH - Animal MH - Cattle MH - Gamma-Globulins/*therapeutic use MH - Leptospirosis/*veterinary MH - Swine MH - Swine Diseases/*drug therapy/prevention & control PT - JOURNAL ARTICLE DA - 700701 DP - 1969 Mar IS - 0042-4846 TA - Veterinariia PG - 36-7 CY - USSR IP - 3 VI - 46 JC - XCC EM - 7008 PMID- 4192141 CU - 95 TT - Lechebno-profilakticheskie svoistva gamma-globulina pri leptospiroze svinei. SO - Veterinariia 1969 Mar;46(3):36-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69241118 AU - Mochmann H TI - [Human leptospirosis in Central Europe] LA - Ger MH - Animal MH - Disease Vectors MH - Europe MH - Human MH - Leptospira/classification/*immunology MH - Leptospirosis/*epidemiology/immunology MH - *Zoonoses PT - JOURNAL ARTICLE DA - 690905 DP - 1969 Feb 15 IS - 0044-2542 TA - Z Gesamte Inn Med PG - Suppl:52-5 SB - M CY - GERMANY, EAST IP - 4 VI - 24 JC - XUY EM - 6910 PMID- 5816037 CU - 88 TT - Leptospirosen des Menschen in Mitteleuropa. SO - Z Gesamte Inn Med 1969 Feb 15;24(4):Suppl:52-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69188631 AU - Michna SW AU - Campbell RS TI - Leptospirosis in pigs: epidemiology, microbiology and pathology. LA - Eng MH - Animal MH - Kidney/pathology MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/epidemiology/microbiology/pathology/*veterinary MH - Scotland MH - Swine MH - *Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 690703 DP - 1969 Feb 8 IS - 0042-4900 TA - Vet Rec PG - 135-8 SB - M CY - ENGLAND IP - 6 VI - 84 JC - XBS EM - 6908 PMID- 5814185 CU - 88 SO - Vet Rec 1969 Feb 8;84(6):135-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 69237782 AU - Howell D AU - Daniels MG AU - Wilson CD AU - Little TW AU - Slavin G AU - Salt GF TI - Leptospirosis in dairy cows. LA - Eng MH - Animal MH - Cattle MH - *Cattle Diseases MH - Female MH - Leptospirosis/immunology/*veterinary MH - Mastitis, Bovine/*etiology MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 690904 DP - 1969 Feb 1 IS - 0042-4900 TA - Vet Rec PG - 122-3 SB - M CY - ENGLAND IP - 5 VI - 84 JC - XBS EM - 6910 PMID- 5815906 CU - 85 SO - Vet Rec 1969 Feb 1;84(5):122-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69155110 AU - Lepherd EE TI - The use of a formolised antigen as a screening test for leptospiral antibodies in horses. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antibodies MH - *Antigens MH - Horse Diseases/*diagnosis MH - Horses MH - Leptospirosis/diagnosis/*veterinary PT - JOURNAL ARTICLE DA - 690520 DP - 1969 Feb IS - 0005-0423 TA - Aust Vet J PG - 46-9 SB - M CY - AUSTRALIA IP - 2 VI - 45 JC - 9IE EM - 6907 PMID- 5813397 CU - 85 SO - Aust Vet J 1969 Feb;45(2):46-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69229639 AU - Gorshanova EN TI - [On the interrelationship of antigens and antibodies in leptospirosis carrier state] LA - Rus MH - Agglutination Tests MH - Animal MH - Antibodies/*analysis MH - Carrier State/*immunology MH - Cattle MH - English Abstract MH - Kidney/immunology MH - Leptospira/immunology MH - Leptospirosis/*immunology MH - Swine PT - JOURNAL ARTICLE DA - 690822 DP - 1969 Feb TA - Zh Mikrobiol Epidemiol Immunobiol PG - 59-63 SB - M CY - USSR IP - 2 VI - 46 JC - Y9O EM - 6910 PMID- 5792182 CU - 89 TT - O Sootnoshenii antigenov i antitel pri leptospironositel'stve. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Feb;46(2):59-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69229635 AU - Khabirova GZ AU - Zaikonnikova TV TI - [On the differentiation of pathogenic and saprophytic leptospira] LA - Rus MH - Copper/pharmacology MH - Culture Media MH - English Abstract MH - Leptospira/drug effects/enzymology/*isolation & purification MH - Oxidoreductases/analysis MH - Sulfates/pharmacology PT - JOURNAL ARTICLE DA - 690822 DP - 1969 Feb TA - Zh Mikrobiol Epidemiol Immunobiol PG - 44-8 SB - M CY - USSR IP - 2 VI - 46 JC - Y9O EM - 6910 PMID- 5792180 CU - 89 TT - O differentsiatsii patogennykh i saprofiticheskikh leptospir. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Feb;46(2):44-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 69229619 AU - Mefod'ev VV TI - [Experience with sanitation in an anthropurgic focus of leptospirosis in the Tumen region] LA - Rus MH - Agricultural Workers' Diseases/*prevention & control MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - Human MH - Leptospirosis/diagnosis/*prevention & control MH - Serodiagnosis MH - Vaccination PT - JOURNAL ARTICLE DA - 690822 DP - 1969 Feb TA - Zh Mikrobiol Epidemiol Immunobiol PG - 136-7 SB - M CY - USSR IP - 2 VI - 46 JC - Y9O EM - 6910 PMID- 5792174 CU - 89 TT - Opyt ozdorovleniia antropurgicheskogo ochaga leptospiroza v tiumenskoi oblasti. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Feb;46(2):136-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 69189513 AU - Piolino M TI - [Renal insufficiency in leptospirosis] LA - Fre MH - Adult MH - Aged MH - Human MH - Kidney Failure, Acute/*etiology MH - Leptospirosis/*complications MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 690703 DP - 1969 Feb IS - 0035-3655 TA - Rev Med Suisse Romande PG - 81-6 CY - SWITZERLAND IP - 2 VI - 89 JC - SR5 EM - 6908 PMID- 5770986 TT - L'insuffisance renale dans la leptospirose. SO - Rev Med Suisse Romande 1969 Feb;89(2):81-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 69106885 AU - De Martino C AU - Bruni CB AU - Bellocci M AU - Natali PG TI - Spontaneous leptospiral infection of the rat kidney. An ultrastructural study. LA - Eng MH - Animal MH - Kidney Diseases/microbiology/*pathology MH - Kidney Tubules/microbiology/*pathology MH - Leptospirosis/*pathology MH - Male MH - Microscopy, Electron MH - Rats PT - JOURNAL ARTICLE DA - 690326 DP - 1969 Feb IS - 0014-4800 TA - Exp Mol Pathol PG - 27-38 SB - M CY - UNITED STATES IP - 1 VI - 10 JC - EQ5 EM - 6905 PMID- 5764538 SO - Exp Mol Pathol 1969 Feb;10(1):27-38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 70153020 AU - Pupkevich-Diamant IaS TI - [Treatment of leptospira infections with antibiotics of the chloromycetin and tetracycline groups] LA - Rus MH - Adolescence MH - Adult MH - Chloramphenicol/*therapeutic use MH - Chlortetracycline/*therapeutic use MH - Female MH - Human MH - Leptospirosis/*drug therapy MH - Male MH - Tetracycline/*therapeutic use PT - JOURNAL ARTICLE DA - 700514 DP - 1969 Feb IS - 0023-2149 TA - Klin Med (Mosk) PG - 126-30 CY - USSR IP - 2 VI - 47 JC - KW2 EM - 7007 PMID- 5379251 TT - O lechenii leptospiroznoi infektsii antibiotikami grupp khloromitsetina i tetratsiklina. SO - Klin Med (Mosk) 1969 Feb;47(2):126-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [41 medline neighbors] UI - 69085940 AU - Almeida JD AU - Waterson AP AU - Berry DM AU - Turner LH TI - Structures associated with leptospires possibly relevant to the Marburg agent. LA - Eng MH - Animal MH - Guinea Pigs MH - Leptospira canicola/*cytology MH - Leptospira interrogans/*cytology MH - Microscopy, Electron MH - Monkey Diseases MH - Staining MH - Virus Diseases MH - *Viruses, Unclassified PT - JOURNAL ARTICLE DA - 690227 DP - 1969 Feb 1 IS - 0140-6736 TA - Lancet PG - 235-7 SB - A SB - M CY - ENGLAND IP - 588 VI - 1 JC - L0S EM - 6904 PMID- 4178592 CU - 95 SO - Lancet 1969 Feb 1;1(588):235-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 69250498 AU - Tsai CC AU - Fresch JW TI - Leptospira canicola isolated from dogs in Taiwan. LA - Eng MH - Animal MH - Dog Diseases/*microbiology MH - Dogs MH - Leptospira canicola/*isolation & purification MH - Leptospirosis/*veterinary MH - Taiwan PT - JOURNAL ARTICLE DA - 690917 DP - 1969 Jan 28 IS - 0371-7682 TA - Taiwan I Hsueh Hui Tsa Chih PG - 58-62 CY - TAIWAN IP - 1 VI - 68 JC - I6V EM - 6911 PMID- 5256459 CU - 88 SO - Taiwan I Hsueh Hui Tsa Chih 1969 Jan 28;68(1):58-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [11 medline neighbors] UI - 69085116 AU - Greenberg JH TI - Public health problems relating to the Vietnam returnee. LA - Eng MH - Cholera/epidemiology MH - Communicable Disease Control MH - *Communicable Diseases MH - Dengue/epidemiology MH - Diarrhea/epidemiology MH - Encephalitis, Japanese/epidemiology MH - Filariasis/epidemiology MH - Helminthiasis/epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Malaria/epidemiology/prevention & control MH - Melioidosis/epidemiology MH - *Military Medicine MH - Military Personnel MH - Plague/epidemiology MH - *Public Health MH - Scrub Typhus/epidemiology MH - Sexually Transmitted Diseases/epidemiology MH - Skin Diseases/epidemiology MH - Tuberculosis/epidemiology MH - United States MH - Vietnam MH - War PT - JOURNAL ARTICLE DA - 690227 DP - 1969 Jan 27 IS - 0098-7484 TA - JAMA PG - 697-702 SB - A SB - M CY - UNITED STATES IP - 4 VI - 207 JC - KFR EM - 6904 PMID- 4302950 CU - 93 SO - JAMA 1969 Jan 27;207(4):697-702 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69259522 AU - Michna SW AU - Campbell RS TI - The isolation of Leptospira sejroe from the kidneys of aborting cattle. LA - Eng MH - Abortion, Veterinary/*microbiology MH - Agglutination Tests MH - Animal MH - Antibodies/analysis MH - Cattle MH - Cattle Diseases/*microbiology MH - Disease Vectors MH - Female MH - Kidney/*microbiology MH - Leptospira/*isolation & purification MH - Pregnancy PT - JOURNAL ARTICLE DA - 690929 DP - 1969 Jan 25 IS - 0042-4900 TA - Vet Rec PG - 83-6 SB - M CY - ENGLAND IP - 4 VI - 84 JC - XBS EM - 6911 PMID- 5816581 CU - 85 SO - Vet Rec 1969 Jan 25;84(4):83-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69086619 AU - Turner LH TI - Leptospirosis. LA - Eng MH - Animal MH - Communicable Disease Control MH - Complement Fixation Tests MH - Diagnosis, Differential MH - Disease Vectors MH - Great Britain MH - Human MH - Immunization, Passive MH - Leptospira/classification MH - *Leptospirosis/diagnosis/drug therapy/epidemiology/immunology MH - Penicillins/therapeutic use MH - Tetracycline/therapeutic use PT - JOURNAL ARTICLE DA - 690228 DP - 1969 Jan 25 IS - 0007-1447 TA - Br Med J PG - 231-5 SB - A SB - M CY - ENGLAND IP - 638 VI - 1 JC - B4W EM - 6904 PMID- 5812537 CU - 88 SO - Br Med J 1969 Jan 25;1(638):231-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69086616 AU - Sakula A AU - Moore W TI - Benign leptospirosis: first reported outbreak in British Isles due to strains belonging to the Hebdomadis serogroup of Leptospira interrogans. LA - Eng MH - Adult MH - Agglutination Tests MH - Animal MH - Cattle MH - Disease Outbreaks MH - Disease Vectors MH - England MH - Human MH - Leptospirosis/complications/diagnosis/drug therapy/*epidemiology/veterinary MH - Male MH - Meningitis/complications MH - Penicillins/therapeutic use MH - Serodiagnosis MH - Serotyping PT - JOURNAL ARTICLE DA - 690228 DP - 1969 Jan 25 IS - 0007-1447 TA - Br Med J PG - 226-8 SB - A SB - M CY - ENGLAND IP - 638 VI - 1 JC - B4W EM - 6904 PMID- 5812536 CU - 88 SO - Br Med J 1969 Jan 25;1(638):226-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69086603 TI - Leptospirosis. LA - Eng MH - Animal MH - Cattle MH - Communicable Disease Control MH - Great Britain MH - Human MH - Leptospirosis/*diagnosis/veterinary MH - Rats MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 690228 DP - 1969 Jan 25 IS - 0007-1447 TA - Br Med J PG - 200 SB - A SB - M CY - ENGLAND IP - 638 VI - 1 JC - B4W EM - 6904 PMID- 5812534 CU - 88 NI - A SO - Br Med J 1969 Jan 25;1(638):200 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 69086617 AU - Coghlan JD AU - Bain AD TI - Leptospirosis in human pregnancy followed by death of the foetus. LA - Eng MH - Adult MH - Agglutination Tests MH - Female MH - Fetal Death/*etiology MH - Fetal Diseases/etiology MH - Human MH - Leptospira canicola/immunology MH - *Leptospirosis/complications/diagnosis MH - Pregnancy MH - *Pregnancy Complications, Infectious MH - Serotyping PT - JOURNAL ARTICLE DA - 690228 DP - 1969 Jan 25 IS - 0007-1447 TA - Br Med J PG - 228-30 SB - A SB - M CY - ENGLAND IP - 638 VI - 1 JC - B4W EM - 6904 PMID- 5762626 SO - Br Med J 1969 Jan 25;1(638):228-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 69226723 AU - Cabanel G AU - Voog R AU - Phelp X TI - [Subacute polyarthritis in grippotyphosic leptospirosis] LA - Fre MH - *Adult MH - Agglutination Tests MH - Arthritis, Infectious/drug therapy/*etiology MH - Dexamethasone/therapeutic use MH - Human MH - Indomethacin/therapeutic use MH - Leptospirosis/*complications/diagnosis/drug therapy MH - Male MH - Oxytetracycline/therapeutic use MH - Penicillin G, Benzathine/therapeutic use MH - Phenylbutazone/therapeutic use MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 690819 DP - 1969 Jan 18 IS - 0032-7867 TA - Presse Med PG - 95-6 SB - M CY - FRANCE IP - 3 VI - 77 JC - PLP EM - 6910 PMID- 5790935 TT - Polyarthrite subaigue au cours d'une leptospirose grippo-typhosique. SO - Presse Med 1969 Jan 18;77(3):95-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 69228831 AU - Nauciel C TI - [Leptospirosis] LA - Fre MH - Animal MH - Animals, Domestic MH - Disease Reservoirs MH - Dogs MH - Human MH - *Leptospirosis MH - Rats PT - JOURNAL ARTICLE DA - 690822 DP - 1969 Jan TA - Cah Coll Med Hop Paris PG - 3-8 CY - FRANCE IP - 1 VI - 10 JC - CC8 EM - 6910 PMID- 5815477 CU - 89 TT - Les leptospiroses. SO - Cah Coll Med Hop Paris 1969 Jan;10(1):3-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69187236 AU - Chernukha YG AU - Isayeva RA AU - Mustafayeva NI TI - Antigenic properties of some strains of leptospirae of the Tarasovi serological group: systematic position of the strain Perepelicin and new serological type Vietnam. LA - Eng MH - Absorption MH - Animal MH - Antibodies MH - Antigens/*analysis MH - Cattle MH - Human MH - Leptospira/classification/*immunology MH - Serotyping MH - Swine PT - JOURNAL ARTICLE DA - 690629 DP - 1969 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 118-25 SB - M CY - CZECHOSLOVAKIA IP - 1 VI - 13 JC - IEV EM - 6908 PMID- 5814135 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1969;13(1):118-25 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69165964 AU - Birzu I AU - Martian I AU - Sborover S TI - [Studies of the incidence of Leptospira infections in man and animals in Oltenia] LA - Rum MH - Animal MH - Animals, Domestic MH - Cattle MH - *Cattle Diseases MH - *Horse Diseases MH - Horses MH - Human MH - Leptospirosis/*epidemiology/*veterinary MH - *Rodent Diseases MH - Romania MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 690605 DP - 1969 Jan-Feb IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 65-70 CY - ROMANIA IP - 1 VI - 14 JC - MXQ EM - 6907 PMID- 5813653 CU - 88 TT - Cercetari privind incidenta infectei leptospirotice la om si animale in Oltenia. SO - Microbiol Parazitol Epidemiol (Bucur) 1969 Jan-Feb;14(1):65-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69264103 AU - Lukaszewicz J AU - Oszczak S TI - [Acute encephalitis during the course of leptospirosis with a rare neurologic syndrome] LA - Pol MH - Adult MH - Antibiotics/therapeutic use MH - *Brain Stem MH - Case Report MH - Encephalitis/*complications MH - English Abstract MH - Hemiplegia/*etiology MH - Human MH - Leptospirosis/*complications/drug therapy MH - Male PT - JOURNAL ARTICLE DA - 691002 DP - 1969 IS - 0033-2100 TA - Przegl Epidemiol PG - 347-8 CY - POLAND IP - 2 VI - 23 JC - Q8T EM - 6911 PMID- 5803043 TT - Ostre zapalenie mozgu w przebiegu leptospirozy z rzadkim zespolem objawow neurologicznych. SO - Przegl Epidemiol 1969;23(2):347-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69212338 AU - Moteiunas LI AU - Urbelene IaA TI - [The role of titrating antileptospirosis antibodies in the retrospective diagnosis of leptospirosis] LA - Rus MH - Agglutination Tests MH - Human MH - Leptospirosis/*diagnosis/immunology PT - JOURNAL ARTICLE DA - 690804 DP - 1969 Jan TA - Zh Mikrobiol Epidemiol Immunobiol PG - 129-31 SB - M CY - USSR IP - 1 VI - 46 JC - Y9O EM - 6909 PMID- 5787561 CU - 89 TT - Rol'titrovaniia protivoleptospiroznykh antitel pri retrospektivnoi diagnostike leptospirozov. SO - Zh Mikrobiol Epidemiol Immunobiol 1969 Jan;46(1):129-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69137448 AU - Faine S TI - Acid-treated, heated serum derivative for culture media for Leptospira. LA - Eng MH - Blood MH - *Culture Media MH - Leptospira/*isolation & purification MH - Leptospira interrogans/isolation & purification PT - JOURNAL ARTICLE DA - 690502 DP - 1969 Jan IS - 0003-6919 TA - Appl Microbiol PG - 185 SB - M CY - UNITED STATES IP - 1 VI - 17 JC - 6K0 EM - 6906 PMID- 5774758 SO - Appl Microbiol 1969 Jan;17(1):185 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69112218 AU - Smibert RM TI - Two colony types of Leptospira semaranga. LA - Eng MH - Antibiotics/pharmacology MH - *Leptospira/drug effects/immunology PT - JOURNAL ARTICLE DA - 690402 DP - 1969 Jan IS - 0008-4166 TA - Can J Microbiol PG - 127-8 SB - M CY - CANADA IP - 1 VI - 15 JC - CJ3 EM - 6905 PMID- 5765169 SO - Can J Microbiol 1969 Jan;15(1):127-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71235302 AU - Mailloux P TI - [Bovine leptospirosis] LA - Fre MH - Africa MH - Animal MH - Asia MH - Australia MH - Cattle MH - *Cattle Diseases/diagnosis/epidemiology/pathology MH - English Abstract MH - Europe MH - France MH - Human MH - Leptospirosis/diagnosis/epidemiology/pathology/*veterinary MH - Serodiagnosis MH - Switzerland MH - United States MH - USSR PT - JOURNAL ARTICLE DA - 710823 DP - 1969 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 661-71 SB - M CY - FRANCE IP - 4 VI - 62 JC - C4G EM - 7110 PMID- 5409144 CU - 88 TT - Les leptospiroses bovines. SO - Bull Soc Pathol Exot Filiales 1969;62(4):661-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [102 medline neighbors] UI - 71210653 AU - Lataste-Dorolle C AU - Fiocre B TI - [Muskrats, Ondatra (Fiber zibethicus, Linnaeus), carriers in France of various leptospirian serotypes: isolation of the 1st French strain related to the Hebdomadis serogroup] LA - Fre MH - Animal MH - *Disease Reservoirs MH - English Abstract MH - France MH - Hamsters MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*microbiology MH - *Rodentia MH - Serotyping MH - *Zoonoses PT - JOURNAL ARTICLE DA - 710729 DP - 1969 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 312-20 SB - M CY - FRANCE IP - 2 VI - 62 JC - C4G EM - 7109 PMID- 5409111 CU - 86 TT - Le rat musque, Ondatra (Fiber zibethicus, Linne) porteur en France de plusieurs serotypes leptospiriens: isolement de la premiere souche francaise reliee au serogrupe Hebdomadis. SO - Bull Soc Pathol Exot Filiales 1969;62(2):312-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 71037960 AU - Sawhney AN AU - Saxena SP TI - Incidence of leptospirosis in cattle in Madhya Pradesh (India). A serological survey. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - India MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 710113 DP - 1969 TA - Izv Mikrobiol Inst (Sofiia) PG - 225-32 CY - BULGARIA VI - 20 JC - H2B EM - 7102 PMID- 5407960 CU - 89 SO - Izv Mikrobiol Inst (Sofiia) 1969;20:225-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 72045073 AU - Derrick EH TI - Estimation of the incubation period of canefield leptospirosis from the weekly work pattern. LA - Eng MH - *Agricultural Workers' Diseases MH - Australia MH - *Biometry MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Time Factors PT - JOURNAL ARTICLE DA - 720125 DP - 1969 Jan IS - 0031-3025 TA - Pathology PG - 73-5 SB - M CY - AUSTRALIA IP - 1 VI - 1 JC - OTA EM - 7203 PMID- 5406461 CU - 90 SO - Pathology 1969 Jan;1(1):73-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 71186519 AU - Simoes J AU - Azevedo JF de AU - Palmeiro JM TI - Some aspects of the Weil's disease epidemiology based on a recent epidemic after a flood in Lisbon (1967). LA - Eng MH - Adolescence MH - Adult MH - *Disasters MH - Disease Reservoirs MH - Human MH - Leptospira/isolation & purification MH - Male MH - Middle Age MH - Portugal MH - Weil's Disease/*epidemiology/microbiology PT - JOURNAL ARTICLE DA - 710701 DP - 1969 Jan-Dec IS - 0075-9767 TA - An Esc Nacl Saude Publica Med Trop (Lisb) PG - 19-32 CY - PORTUGAL IP - 1 VI - 3 JC - 492 EM - 7108 PMID- 5404997 CU - 88 SO - An Esc Nacl Saude Publica Med Trop (Lisb) 1969 Jan-Dec;3(1):19-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 71002076 AU - Mochmann H TI - [Leptospiroses of man in central Europe] LA - Ger MH - Europe MH - Germany, East MH - Human MH - Leptospirosis/complications/*epidemiology MH - Serotyping MH - Weil's Disease/epidemiology PT - JOURNAL ARTICLE DA - 701120 DP - 1969 Jan 1 IS - 0044-2542 TA - Z Gesamte Inn Med PG - Suppl:52-5 SB - M CY - GERMANY, EAST IP - 1 VI - 24 JC - XUY EM - 7101 PMID- 5402593 CU - 88 TT - Leptospirosen des Menschen in Mitteleuropa. SO - Z Gesamte Inn Med 1969 Jan 1;24(1):Suppl:52-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 70210070 AU - Djakov L TI - [Pathomorphological changes of fetuses in various types of porcine abortions] LA - Ger MH - *Abortion, Veterinary MH - Animal MH - Diagnosis, Differential MH - Edema MH - English Abstract MH - Female MH - Fetal Diseases/pathology/*veterinary MH - Hemorrhage MH - Histiocytes MH - Kidney/pathology MH - Leptospirosis/veterinary MH - Leukocytes MH - Liver/pathology MH - Lymphocytes MH - Mycoses/veterinary MH - Myocardium/pathology MH - Necrosis MH - Pregnancy MH - Rickettsia Infections/veterinary MH - Swine MH - Swine Diseases/*pathology MH - Telencephalon/pathology PT - JOURNAL ARTICLE DA - 700807 DP - 1969 IS - 0003-9055 TA - Arch Exp Veterinarmed PG - 407-14 SB - M CY - GERMANY, EAST IP - 2 VI - 23 JC - 70I EM - 7009 PMID- 5396047 CU - 86 TT - Pathomorphologische Veranderungen der Foten bei einigen Abortarten der Schweine. SO - Arch Exp Veterinarmed 1969;23(2):407-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [145 medline neighbors] UI - 70079059 AU - Comby F AU - Gauthier R AU - Nazimoff O TI - [New contribution to the study of leptospirosis in Reunion. II. Anatomopathology and histopathology of 10 fatal cases] LA - Fre MH - Adult MH - Blood Coagulation Disorders/etiology MH - Blood Vessels/pathology MH - English Abstract MH - Female MH - Hemorrhage/etiology MH - Human MH - Indian Ocean Islands MH - Kidney/pathology MH - Leptospirosis/*epidemiology/*pathology MH - Liver/pathology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 700217 DP - 1969 Jan-Feb IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 92-101 SB - M CY - FRANCE IP - 1 VI - 62 JC - C4G EM - 7004 PMID- 5395506 CU - 88 TT - Nouvelle contribution a l'etude des leptospiroses a la Reunion. II. Anatomopathologie et histopathologie de dix cas mortels. SO - Bull Soc Pathol Exot Filiales 1969 Jan-Feb;62(1):92-101 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70281975 AU - Fuchs GH TI - [Experience with Leptospira biflexa antigens in laboratory diagnosis of suspect cases of leptospirosis] LA - Ger MH - Agglutination Tests/*standards MH - Animal MH - *Antigens MH - Cattle MH - Diagnosis, Differential MH - English Abstract MH - Human MH - Immune Sera MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/immunology MH - Serotyping MH - Statistics PT - JOURNAL ARTICLE DA - 701023 DP - 1969 Jan TA - Zentralbl Bakteriol [Orig] PG - 261-7 SB - M CY - GERMANY, WEST IP - 2 VI - 209 JC - Y4Y EM - 7012 PMID- 5394173 CU - 89 TT - Erfahrungen mit Leptospira-biflexa-Antigenen bei der Laboratoriumsdiagnostik von Leptospirose-Verdachtsfallen. SO - Zentralbl Bakteriol [Orig] 1969 Jan;209(2):261-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70184685 AU - Lavrent'ev NI TI - [Etiology of leptospirosis in animals] LA - Rus MH - Agriculture MH - Animal MH - Cattle MH - Cattle Diseases/etiology MH - *Disease Reservoirs MH - Dog Diseases/etiology MH - Dogs MH - Horse Diseases/etiology MH - Horses MH - Leptospirosis/etiology/*veterinary MH - Mammals MH - Swine MH - Swine Diseases/etiology PT - JOURNAL ARTICLE DA - 700701 DP - 1969 Jan IS - 0042-4846 TA - Veterinariia PG - 30-2 CY - USSR IP - 1 VI - 46 JC - XCC EM - 7008 PMID- 5393583 CU - 85 TT - Etiologiia leptospiroza ahivotnykh. SO - Veterinariia 1969 Jan;46(1):30-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [126 medline neighbors] UI - 70089364 AU - Stiepanchonok-Rudnik GI AU - Potashova LA AU - Chernukha GY TI - Chemical analysis of cell fractions of some strains of Leptospirae. LA - Eng MH - Culture Media MH - Leptospira/*analysis MH - Polysaccharides, Bacterial/*analysis MH - Serotyping PT - JOURNAL ARTICLE DA - 700305 DP - 1969 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 506-13 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 13 JC - IEV EM - 7004 PMID- 5391991 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1969;13(4):506-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 70007371 AU - Varela G AU - Velasco R TI - [Serological investigation of animal leptospirosis in the Mexican republic] LA - Spa MH - Agglutination Tests MH - Animal MH - Animal Diseases/*immunology MH - Cats MH - Cattle MH - Chickens MH - Dogs MH - English Abstract MH - Horse Diseases MH - Horses MH - Leptospira/immunology MH - Leptospirosis/blood/*epidemiology MH - Mexico MH - Rabbits MH - Species Specificity PT - JOURNAL ARTICLE DA - 691202 DP - 1969 Jan-Mar IS - 0034-8384 TA - Rev Invest Salud Publica PG - 101-3 CY - MEXICO IP - 1 VI - 29 JC - SCY EM - 7001 PMID- 5387999 CU - 88 TT - Investigacion serologica en la republica Mexicana de leptospirosis en animales. SO - Rev Invest Salud Publica 1969 Jan-Mar;29(1):101-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70255791 AU - Fuchs GH TI - [Proposals for standardization of antigens for the serodiagnosis of leptospirosis] LA - Ger MH - Age Factors MH - Agglutination Tests/standards MH - Antigens/*standards MH - English Abstract MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/immunology MH - Light PT - JOURNAL ARTICLE DA - 700923 DP - 1969 IS - 0003-9055 TA - Arch Exp Veterinarmed PG - 1183-9 SB - M CY - GERMANY, EAST IP - 6 VI - 23 JC - 70I EM - 7011 PMID- 5384474 CU - 84 TT - Vorschlage zur Standardisierung von Antigenen fur die Serodiagnostik der Lptospirose. SO - Arch Exp Veterinarmed 1969;23(6):1183-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70103099 AU - Ujhazyova-Kralikova D AU - Veljacikova Z TI - [Neurologic conditions following leptospira infection] LA - Slo MH - Adult MH - English Abstract MH - Female MH - Follow-Up Studies MH - Human MH - Leptospira/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - *Neurologic Manifestations PT - JOURNAL ARTICLE DA - 700317 DP - 1969 IS - 0006-9248 TA - Bratisl Lek Listy PG - 573-6 CY - CZECHOSLOVAKIA IP - 5 VI - 52 JC - B5N EM - 7005 PMID- 5368609 TT - Nasledne neurologicke stavy po prekonani leptospirovej infekcie. SO - Bratisl Lek Listy 1969;52(5):573-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71126513 AU - Hanson LE AU - Martin RJ AU - Gibbons RW AU - Schnurrenberger PR TI - Equine leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Endophthalmitis/veterinary MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/epidemiology/*veterinary MH - Serotyping PT - JOURNAL ARTICLE DA - 710413 DP - 1969 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 169-80 CY - UNITED STATES VI - 73 JC - PY5 EM - 7106 PMID- 5313252 CU - 89 SO - Proc Annu Meet U S Anim Health Assoc 1969;73:169-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 70029789 AU - Tan DS TI - Sensitized-erythrocyte-lysis (SEL) test as an epidemiological tool for human leptospirosis serological surveys. LA - Eng MH - Antibodies/*analysis MH - Antibody Formation MH - Antigens MH - Epidemiologic Methods MH - Erythrocytes/*immunology MH - Hemagglutination Tests MH - Human MH - Immune Sera MH - Leptospira/immunology MH - Leptospirosis/*diagnosis/immunology MH - Malaysia MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 691223 DP - 1969 IS - 0042-9686 TA - Bull World Health Organ PG - 899-902 CY - SWITZERLAND IP - 6 VI - 40 JC - C80 EM - 7002 PMID- 5307602 CU - 89 SO - Bull World Health Organ 1969;40(6):899-902 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 69286816 AU - Ben-Efraim S AU - Torten M TI - Hypersensitivity reactions in experimental leptospirosis. LA - Eng MH - Anaphylaxis MH - Animal MH - Antibodies/analysis MH - Dogs MH - Endophthalmitis/etiology/*immunology MH - Eye/pathology MH - Guinea Pigs MH - Hypersensitivity, Delayed/*immunology MH - Leptospira MH - Leptospira canicola MH - Leptospirosis/complications/*immunology MH - Skin Tests MH - Species Specificity PT - JOURNAL ARTICLE DA - 691025 DP - 1969 IS - 0020-5915 TA - Int Arch Allergy Appl Immunol PG - 216-7 SB - M CY - SWITZERLAND IP - 1 VI - 36 JC - GP9 EM - 6912 PMID- 5306809 CU - 89 SO - Int Arch Allergy Appl Immunol 1969;36(1):216-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 88159149 AU - Becker K TI - [Transmission of Leptospira by rats in a large city (Berlin)] LA - Ger MH - Animal MH - Berlin MH - *Disease Vectors MH - English Abstract MH - Female MH - *Health MH - Human MH - Male MH - Rats/*microbiology MH - *Urban Health MH - Weil's Disease/*transmission PT - JOURNAL ARTICLE DA - 880414 DP - 1969 IS - 0300-8665 TA - Schriftenr Ver Wasser Boden Lufthyg PG - 49-66 SB - M CY - GERMANY, WEST VI - 32 JC - UDI EM - 8806 PMID- 5293931 CU - 90 NP - X TT - Die Verbreitung der Leptospiren bei Ratten in einer Grossstadt (Berlin). EA - A SO - Schriftenr Ver Wasser Boden Lufthyg 1969;32:49-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 71126547 AU - Trainer DO TI - A new role for wildlife in disease epizootiology. LA - Eng MH - Animal MH - Animal Diseases/*epidemiology MH - Canada MH - Deer MH - Encephalitis, Epidemic/epidemiology/*veterinary MH - Human MH - Leptospirosis/epidemiology/*veterinary MH - Poultry Diseases/epidemiology MH - Rabbits MH - Turkeys MH - United States PT - JOURNAL ARTICLE DA - 710413 DP - 1969 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 582-8 CY - UNITED STATES VI - 73 JC - PY5 EM - 7106 PMID- 5278196 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1969;73:582-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 71126514 AU - Smith LL TI - Chronic Leptospira hardjo and Leptospira hebdomadis infection in a fifty cow herd of dairy cattle, a case history. LA - Eng MH - Abortion, Veterinary MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Chronic Disease MH - Disease Outbreaks/veterinary MH - Female MH - Leptospirosis/epidemiology/*veterinary MH - Male MH - Pregnancy MH - Wisconsin PT - JOURNAL ARTICLE DA - 710413 DP - 1969 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 181-3 CY - UNITED STATES VI - 73 JC - PY5 EM - 7106 PMID- 5278174 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1969;73:181-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 71039172 AU - Reiley CG AU - Russell PK TI - Observations on fevers of unknown origin in the Rephblic of Vietnam. LA - Eng MH - Arbovirus Infections/*epidemiology MH - Chikungunya Virus MH - Dengue/epidemiology MH - Fever/*epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Malaria/epidemiology MH - *Military Medicine MH - Scrub Typhus/epidemiology MH - Vietnam PT - JOURNAL ARTICLE DA - 710113 DP - 1969 Jan IS - 0026-4075 TA - Mil Med PG - 36-42 CY - UNITED STATES IP - 1 VI - 134 JC - N1A EM - 7102 PMID- 4991620 CU - 91 SO - Mil Med 1969 Jan;134(1):36-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 71006422 AU - Zlatev S AU - Vasilevska M TI - Methods for the investigation of the nucleotide compositon of DNA in leptospirae. LA - Eng MH - Chromatography, Paper MH - *DNA, Bacterial MH - Leptospira/*cytology MH - Nucleotides/*analysis PT - JOURNAL ARTICLE DA - 701201 DP - 1969 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 267-70 CY - BULGARIA IP - 4 VI - 11 JC - F19 EM - 7101 PMID- 4990388 CU - 91 SO - Folia Med (Plovdiv) 1969;11(4):267-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 70029609 AU - Ratner JJ AU - Pinkerton ME AU - Kalter SS AU - Guilloud NB TI - Antibodies in nonhuman primate to selected bacterial antigens. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antibody Formation MH - *Antigen-Antibody Reactions MH - Brucella abortus MH - English Abstract MH - Francisella tularensis MH - Haplorhini MH - Human MH - Leptospira MH - Primates/*immunology MH - Proteus MH - Salmonella PT - JOURNAL ARTICLE DA - 691222 DP - 1969 TA - Z Versuchstierkd PG - 146-54 CY - GERMANY, EAST IP - 3 VI - 11 JC - Y2B EM - 7002 PMID- 4981658 CU - 91 SO - Z Versuchstierkd 1969;11(3):146-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 72091703 AU - Bender F TI - [Therapy of meningitides] LA - Ger MH - Age Factors MH - Amphotericin B/therapeutic use MH - Antibiotics/administration & dosage/therapeutic use MH - Cryptococcus MH - Escherichia coli Infections MH - Human MH - Injections, Intravenous MH - Injections, Spinal MH - Intracranial Pressure MH - Leptospira MH - Meningitis/cerebrospinal fluid/*drug therapy/microbiology/therapy MH - Meningitis, Haemophilus/drug therapy MH - Meningitis, Listeria/drug therapy MH - Meningitis, Meningococcal/drug therapy MH - Meningitis, Pneumococcal/drug therapy MH - Meningitis, Viral/therapy MH - Microbial Sensitivity Tests MH - Penicillins/therapeutic use MH - Staphylococcal Infections MH - Streptococcal Infections MH - Streptomycin/therapeutic use MH - Sulfonamides/therapeutic use MH - Tuberculosis, Meningeal/drug therapy PT - JOURNAL ARTICLE DA - 720403 DP - 1969 TA - Bibl Psychiatr Neurol PG - 635-47 SB - M CY - SWITZERLAND VI - 139 JC - 9WG EM - 7205 PMID- 4944736 CU - 90 TT - Therapie der Meningtiden. SO - Bibl Psychiatr Neurol 1969;139:635-47 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70228110 AU - Zorabian IS TI - [Leptospira count by blood-smear method] LA - Rus MH - *Bacteriological Techniques MH - Cell Count MH - Culture Media MH - Erythrocyte Count MH - Leptospira/*isolation & purification PT - JOURNAL ARTICLE DA - 700821 DP - 1969 TA - Zh Eksp Klin Med PG - 30-3 CY - USSR IP - 5 VI - 9 JC - Y9J EM - 7010 PMID- 4913232 CU - 90 TT - O podschete leptospir metodom krovianykh mazkov. SO - Zh Eksp Klin Med 1969;9(5):30-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 70155285 AU - Fuchs GH AU - Burger G TI - [Methodical problems of differentiation of parasitic and saprogenic leptospires by means of copper sulfate] LA - Ger MH - Acetates/pharmacology MH - *Bacteriological Techniques MH - Chlorides/pharmacology MH - Copper/*pharmacology MH - Densitometry MH - Depression, Chemical MH - English Abstract MH - Leptospira/classification/drug effects/*growth & development MH - Statistics MH - Sulfates/pharmacology MH - Suspensions PT - JOURNAL ARTICLE DA - 700519 DP - 1969 TA - Zentralbl Bakteriol [Orig] PG - 382-8 SB - M CY - GERMANY, WEST IP - 3 VI - 209 JC - Y4Y EM - 7007 PMID- 4908515 CU - 90 TT - Methodische Probleme zur Differenzierung von parasitaren und saprobischen Leptospiren mittels Kupfersulfat. SO - Zentralbl Bakteriol [Orig] 1969;209(3):382-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [111 medline neighbors] UI - 70065859 AU - Van Dijck PJ TI - Further bacteriological evaluation of virginiamycin. LA - Eng MH - Animal MH - Antibiotics/*pharmacology/therapeutic use MH - Bacteriological Techniques MH - Clostridium/drug effects MH - Culture Media MH - Drug Synergism MH - Enterobacteriaceae/*drug effects MH - Haemophilus/drug effects MH - Leptospira/drug effects MH - Malaria/drug therapy MH - Mice MH - Microbial Sensitivity Tests MH - Mycobacterium/drug effects MH - Plasmodium MH - Protozoan Infections/drug therapy MH - Staphylococcal Infections/drug therapy MH - Streptococcal Infections/drug therapy MH - Toxoplasmosis/drug therapy MH - Trichomonas/drug effects MH - Virginiamycin/pharmacology/therapeutic use PT - JOURNAL ARTICLE DA - 700205 DP - 1969 IS - 0009-3157 TA - Chemotherapy PG - 322-32 SB - M CY - SWITZERLAND IP - 5 VI - 14 JC - D15 EM - 7003 PMID- 4902789 CU - 90 SO - Chemotherapy 1969;14(5):322-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70012578 TI - [Vasilii Vasil'evich Anan'in] LA - Rus MH - Epidemiology/history MH - History of Medicine, 20th Cent. MH - Leptospirosis MH - Microbiology/history MH - USSR PT - BIOGRAPHY PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 691205 DP - 1969 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 150 SB - M CY - USSR IP - 6 VI - 46 JC - Y9O EM - 7001 PMID- 4899556 CU - 96 NI - A PS - Anan'in VV TT - Vasilii Vasil'evich Anan'in. SO - Zh Mikrobiol Epidemiol Immunobiol 1969;46(6):150 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [19 medline neighbors] UI - 71250908 TI - [Veterinary medicine] LA - Mul MH - Animal MH - Animal Nutrition MH - *Bibliography MH - Brucellosis/veterinary MH - Coccidiosis/veterinary MH - Deficiency Diseases/veterinary MH - Food Poisoning/veterinary MH - Helminthiasis/veterinary MH - Infection/veterinary MH - Leptospirosis/veterinary MH - Mite Infestations/veterinary MH - Nematode Infections/veterinary MH - Parasitic Diseases/veterinary MH - Pleuropneumonia/veterinary MH - Protozoan Infections/veterinary MH - Rickettsia Infections/veterinary MH - Tick Infestations/veterinary MH - Trypanosomiasis/veterinary MH - *Veterinary Medicine MH - Virus Diseases/veterinary PT - BIBLIOGRAPHY PT - JOURNAL ARTICLE DA - 710915 DP - 1969 IS - 0001-706X TA - Acta Trop PG - 76-92 SB - M CY - SWITZERLAND IP - 1 VI - 26 JC - 23A EM - 7111 PMID- 4397651 CU - 94 NI - A SO - Acta Trop 1969;26(1):76-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [109 medline neighbors] UI - 70012566 AU - Aguzarova MKh AU - Tseboeva AA AU - Rumiantseva NI AU - Tonkonozhenko AP AU - Gurdanova EI TI - [New foci of leptospirosis in the pre-forest and forest-steppe zones of North-Osetia ASSR] LA - Rus MH - Adolescence MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Child MH - Child, Preschool MH - Disease Reservoirs/epidemiology MH - Human MH - Leptospirosis/*epidemiology/etiology MH - Mice MH - Rodent Diseases/epidemiology MH - Russia MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 691205 DP - 1969 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 137 SB - M CY - USSR IP - 6 VI - 46 JC - Y9O EM - 7001 PMID- 4242150 CU - 92 TT - Novye Ochagi leptospiroza v predlesnoi i lesostepnoi zanakh Severo- Osetinskoi ASSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1969;46(6):137 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [123 medline neighbors] UI - 69285602 AU - Godlevskaia MV AU - Drankin DI AU - Rumiantseva EV AU - Pevzner IN AU - Shanina RIa AU - El'kina AV TI - [Zoonoses among workers of the tanning industry] LA - Rus MH - Animal MH - Anthrax/epidemiology MH - Brucellosis/epidemiology MH - English Abstract MH - Human MH - Leptospirosis/epidemiology MH - *Occupational Diseases MH - Ornithosis/epidemiology MH - Q Fever/epidemiology MH - Russia MH - *Tanning MH - Toxoplasmosis/epidemiology MH - Tularemia/epidemiology MH - *Zoonoses PT - JOURNAL ARTICLE DA - 691023 DP - 1969 Jan IS - 0016-9919 TA - Gig Tr Prof Zabol PG - 7-11 CY - USSR IP - 1 VI - 13 JC - FQ9 EM - 6912 PMID- 4241308 CU - 92 TT - Zoonozy sredi rabochikh kozhevennoi promyshlennosti. SO - Gig Tr Prof Zabol 1969 Jan;13(1):7-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 70133680 AU - Riel J van AU - Demonty J TI - [A case of leptospirosis in the Liege region] LA - Fre MH - Adult MH - Animal MH - *Disease Vectors MH - Fishes MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Sports PT - JOURNAL ARTICLE DA - 700422 DP - 1968 Dec 15 IS - 0035-3663 TA - Rev Med Liege PG - 778-84 CY - BELGIUM IP - 24 VI - 23 JC - SM9 EM - 7006 PMID- 5754328 CU - 88 TT - Sur un cas de leptospirose dans la region liegeoise. SO - Rev Med Liege 1968 Dec 15;23(24):778-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70184649 AU - Kir'ianov EA TI - [Leptospirosis of agricultural animals in Primorskii Territory] LA - Rus MH - *Agriculture MH - Animal MH - *Animal Diseases MH - Disease Reservoirs MH - Leptospirosis/*veterinary MH - Siberia PT - JOURNAL ARTICLE DA - 700701 DP - 1968 Dec IS - 0042-4846 TA - Veterinariia PG - 70-2 CY - USSR IP - 12 VI - 45 JC - XCC EM - 7008 PMID- 5754486 CU - 85 TT - Leptospiroz sel'shokhoziaistvennykh zhivotnykh v Primor'e. SO - Veterinariia 1968 Dec;45(12):70-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70184624 AU - Zaichenko AS TI - [Prolonged complement fixation test in the diagnosis of leptospirosis] LA - Rus MH - Animal MH - Complement Fixation Tests/*veterinary MH - Leptospirosis/diagnosis/*veterinary MH - Time Factors PT - JOURNAL ARTICLE DA - 700701 DP - 1968 Dec IS - 0042-4846 TA - Veterinariia PG - 106-8 CY - USSR IP - 12 VI - 45 JC - XCC EM - 7008 PMID- 5754475 CU - 90 TT - Reaktsiia dlitel'nogo sviazyvaniia komplementa v diagnostike leptospiroza. SO - Veterinariia 1968 Dec;45(12):106-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 69276955 AU - Valova GP AU - Mefod'ev VV TI - [Results of a study of the epidemiology of leptospirosis in northwestern Siberia] LA - Rus MH - Animal MH - Animal Diseases/epidemiology MH - Bird Diseases/epidemiology MH - Cattle MH - Cattle Diseases/epidemiology MH - *Disease Vectors MH - Human MH - Leptospirosis/*epidemiology/etiology MH - Reindeer MH - Rodent Diseases/*epidemiology MH - Siberia MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 691016 DP - 1968 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 116-7 SB - M CY - USSR IP - 12 VI - 45 JC - Y9O EM - 6912 PMID- 5753707 CU - 89 TT - Itogi izucheniia epidemiologii leptospirozov na severe zapadnoi Sibiri. SO - Zh Mikrobiol Epidemiol Immunobiol 1968 Dec;45(12):116-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 69115114 AU - Hughes KL AU - Young JS AU - Moyle GG TI - Serological examination for evidence of brucellosis and leptospirosis in beef herds in New South Wales. LA - Eng MH - Agglutination Tests MH - Animal MH - Australia MH - Brucellosis, Bovine/*blood MH - Cattle MH - Leptospirosis/blood/*veterinary PT - JOURNAL ARTICLE DA - 690408 DP - 1968 Dec IS - 0005-0423 TA - Aust Vet J PG - 557-61 SB - M CY - AUSTRALIA IP - 12 VI - 44 JC - 9IE EM - 6905 PMID- 5751645 CU - 85 SO - Aust Vet J 1968 Dec;44(12):557-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 70010596 AU - Nicosia A AU - Munao F AU - Ioli A TI - [Experimental uveitis caused by Leptospira. II. Study of the pathogenic fractions of Leptospira obtained by ultracentrifugation] LA - Ita MH - Animal MH - *Choroiditis MH - Leptospira canicola/*pathogenicity MH - *Leptospirosis MH - Rabbits MH - Ultracentrifugation MH - *Uveitis PT - JOURNAL ARTICLE DA - 691204 DP - 1968 Dec IS - 0003-4665 TA - Ann Ottalmol Clin Ocul PG - 1449-56 CY - ITALY IP - 12 VI - 94 JC - 5RA EM - 7001 PMID- 5735927 TT - Uveite sperimentale da Leptospira. II. Studio di frazioni patogene della leptospira ottenute mediante ultracentrifugazione. SO - Ann Ottalmol Clin Ocul 1968 Dec;94(12):1449-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69212494 AU - Spradbrow PB TI - The susceptibility of mice to Leptospira pomona. LA - Eng MH - Animal MH - Leptospira/*pathogenicity MH - Leptospirosis/mortality/urine MH - *Mice MH - Time Factors PT - JOURNAL ARTICLE DA - 690805 DP - 1968 Dec IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 787-9 SB - M CY - AUSTRALIA IP - 6 VI - 46 JC - 9FW EM - 6909 PMID- 5729732 CU - 90 SO - Aust J Exp Biol Med Sci 1968 Dec;46(6):787-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 69101711 AU - Babudieri B AU - Smith DJ TI - A serological study of the Leptospira strain Ictero No. I of Inada et al. 1916. LA - Eng MH - Agglutination Tests MH - Case Report MH - Human MH - Leptospira/classification/isolation & purification MH - Male MH - Middle Age MH - Weil's Disease/*immunology PT - JOURNAL ARTICLE DA - 690318 DP - 1968 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 379-84 SB - M CY - NETHERLANDS IP - 4 VI - 20 JC - WGJ EM - 6905 PMID- 5707224 SO - Trop Geogr Med 1968 Dec;20(4):379-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 70026729 AU - Mezhennyi AM TI - [Characteristics of the immunologic structure of the population in relation to leptospirosis] LA - Rus MH - Adolescence MH - Adult MH - Age Factors MH - Agglutination Tests MH - Child MH - Child, Preschool MH - English Abstract MH - Human MH - *Immunity, Active MH - Infant MH - Leptospirosis/blood/epidemiology/*immunology MH - Meat-Packing Industry MH - Rural Population MH - Russia MH - Urban Population PT - JOURNAL ARTICLE DA - 691218 DP - 1968 Dec IS - 0038-5077 TA - Sov Med PG - 47-51 CY - USSR IP - 12 VI - 31 JC - UW7 EM - 7002 PMID- 4242327 CU - 92 TT - Osobennosti immunologicheskoi struktury naseleniia v otnoshenii leptospiroznoi infektsii. SO - Sov Med 1968 Dec;31(12):47-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 69276984 AU - Guzairova EA TI - [A study of the antigenic properties of pathogenic leptospira isolated in Khirgizia] LA - Rus MH - Absorption MH - Animal MH - Animal Diseases/*etiology MH - Cattle MH - Cattle Diseases/etiology MH - English Abstract MH - Human MH - Kidney/microbiology MH - Kyrgyzstan MH - Leptospira/*immunology MH - Leptospirosis/*etiology/microbiology MH - Mice MH - Rodent Diseases/etiology MH - Swine MH - Swine Diseases/etiology PT - JOURNAL ARTICLE DA - 691016 DP - 1968 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 74-6 SB - M CY - USSR IP - 12 VI - 45 JC - Y9O EM - 6912 PMID- 4241071 CU - 92 TT - Izuchenie antigennykh svoistv patogennykh leptospir, vydelennykh v Kirgizskoi SSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1968 Dec;45(12):74-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 69276961 AU - Guzairova EA TI - [A study of the properties of strains of leptospira isolated in Khirgizia] LA - Rus MH - Copper/*metabolism MH - Human MH - Kyrgyzstan MH - Leptospira/drug effects/enzymology/*metabolism/pathogenicity MH - Leptospirosis/etiology/microbiology MH - Lipase/*analysis PT - JOURNAL ARTICLE DA - 691016 DP - 1968 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 121 SB - M CY - USSR IP - 12 VI - 45 JC - Y9O EM - 6912 PMID- 4241069 CU - 92 TT - Izuchenie svoistv shtammov leptospir, vydelennykh v Kirgizii. SO - Zh Mikrobiol Epidemiol Immunobiol 1968 Dec;45(12):121 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70008649 AU - Frezza L AU - Sindoni L AU - Tredici E TI - [Attempted isolation of pathogenic leptospira from wild birds (Coturnix coturnix)] LA - Ita MH - Animal MH - *Bird Diseases MH - Leptospira/*isolation & purification MH - *Leptospirosis PT - JOURNAL ARTICLE DA - 691202 DP - 1968 Nov 30 IS - 0037-8771 TA - Boll Soc Ital Biol Sper PG - 1921-3 SB - M CY - ITALY IP - 22 VI - 44 JC - ALS EM - 7001 PMID- 5753837 CU - 85 TT - Tentativi di isolamento di leptospire patogene da fauna avicola selvatica (Coturnix coturnix) SO - Boll Soc Ital Biol Sper 1968 Nov 30;44(22):1921-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69055923 AU - Corbould A TI - Leptospirosis icterohemorrhagiae in dogs in Tasmania. LA - Eng MH - Animal MH - Australia MH - Dog Diseases/*epidemiology MH - Dogs MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 690128 DP - 1968 Nov IS - 0005-0423 TA - Aust Vet J PG - 529 SB - M CY - AUSTRALIA IP - 11 VI - 44 JC - 9IE EM - 6903 PMID- 5749416 CU - 88 SO - Aust Vet J 1968 Nov;44(11):529 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69296903 AU - Ovchinnikov NM AU - Delektorskii VV TI - [The morphology of Treponema pallidum and leptospirae (electron microscopic study)] LA - Rus MH - Cell Membrane MH - English Abstract MH - Leptospira/*cytology MH - Microscopy, Electron MH - *Treponema pallidum PT - JOURNAL ARTICLE DA - 691105 DP - 1968 Nov TA - Zh Mikrobiol Epidemiol Immunobiol PG - 131-5 SB - M CY - USSR IP - 11 VI - 45 JC - Y9O EM - 6912 PMID- 4898170 CU - 90 TT - Morfologiia blednoi treponemy i leptospir (elektronnomikroslipicheskoe issledovanie) SO - Zh Mikrobiol Epidemiol Immunobiol 1968 Nov;45(11):131-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70217803 AU - Pupkevich-Diamant IaS AU - Boguslavskii VS TI - [Certain problems of the epidemiology and clinical aspects of leptospirosis in the Novocherkassk Region] LA - Rus MH - Adolescence MH - Adult MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Russia PT - JOURNAL ARTICLE DA - 700811 DP - 1968 Nov IS - 0038-5077 TA - Sov Med PG - 106-10 CY - USSR IP - 11 VI - 31 JC - UW7 EM - 7009 PMID- 4246533 CU - 92 TT - Nekotorye voprosy emidemiologii i kliniki leptospiroza v raione Novocherkasska. SO - Sov Med 1968 Nov;31(11):106-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [190 medline neighbors] UI - 69191783 AU - Illartein PR AU - Mailloux M TI - [Experimental study on serum antileptospire agglutinins in dogs] LA - Fre MH - Animal MH - *Antibodies MH - Dog Diseases/*immunology MH - Dogs MH - Leptospirosis/*immunology/veterinary PT - JOURNAL ARTICLE DA - 690708 DP - 1968 Oct IS - 0001-4192 TA - Bull Acad Vet Fr PG - 313-8 CY - FRANCE IP - 8 VI - 41 JC - BA8 EM - 6908 PMID- 5714035 TT - Recherches experimentales sur les agglutinines seriques antileptospires chez le chien. SO - Bull Acad Vet Fr 1968 Oct;41(8):313-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 69004917 AU - Port CD AU - Holmes CL TI - A conditioning program for random source dogs. LA - Eng MH - Animal MH - *Animals, Laboratory MH - Distemper/*immunology MH - Dog Diseases/*prevention & control MH - Dogs MH - Hepatitis, Animal/*immunology MH - Leptospirosis/immunology/*veterinary MH - Physical Examination/veterinary MH - Rabies/*immunology PT - JOURNAL ARTICLE DA - 681124 DP - 1968 Oct 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 785-8 SB - M CY - UNITED STATES IP - 7 VI - 153 JC - HAV EM - 6901 PMID- 5692911 CU - 85 SO - J Am Vet Med Assoc 1968 Oct 1;153(7):785-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 69004603 AU - Finco DR AU - Low DG TI - Fibrinogen content and fibrinolytic acitivity of plasma from dogs infected with Leptospira canicola. LA - Eng MH - Animal MH - Dog Diseases/*blood MH - Dogs MH - Fibrinogen/*blood MH - *Fibrinolysis MH - Leptospirosis/blood/*veterinary PT - JOURNAL ARTICLE DA - 681124 DP - 1968 Oct IS - 0002-9645 TA - Am J Vet Res PG - 2037-40 SB - M CY - UNITED STATES IP - 10 VI - 29 JC - 40C EM - 6901 PMID- 5692895 CU - 85 SO - Am J Vet Res 1968 Oct;29(10):2037-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69025010 AU - Henneberry RC AU - Cox CD TI - Antigenic analysis of water forms of Leptospira. LA - Eng MH - Agglutination Tests MH - Antigens/*analysis MH - Leptospira/analysis/*classification MH - Serotyping MH - Water Microbiology PT - JOURNAL ARTICLE DA - 681209 DP - 1968 Oct IS - 0021-9193 TA - J Bacteriol PG - 1419-20 SB - M CY - UNITED STATES IP - 4 VI - 96 JC - HH3 EM - 6901 PMID- 5686005 SO - J Bacteriol 1968 Oct;96(4):1419-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 69013297 AU - Johnson RC AU - Harris VG TI - Purine analogue sensitivity and lipase activity of leptospires. LA - Eng MH - Adenine/metabolism MH - Azaguanine/pharmacology MH - Carbon Isotopes MH - *Leptospira/classification/drug effects/enzymology/pathogenicity MH - Lipase/*metabolism MH - Purines/*pharmacology PT - JOURNAL ARTICLE DA - 681208 DP - 1968 Oct IS - 0003-6919 TA - Appl Microbiol PG - 1584-90 SB - M CY - UNITED STATES IP - 10 VI - 16 JC - 6K0 EM - 6901 PMID- 5684206 SO - Appl Microbiol 1968 Oct;16(10):1584-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69092204 AU - Juan FS AU - Duarte F AU - Treiger M AU - Rios Goncalves AJ TI - [Histological aspects and liver functions in icter-hemorrhagic leptospirosis] LA - Por MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Liver/*physiopathology MH - Liver Function Tests MH - Male MH - Middle Age MH - Weil's Disease/*physiopathology PT - JOURNAL ARTICLE DA - 690307 DP - 1968 Oct IS - 0018-5469 TA - Hospital (Rio J) PG - 1125-48 CY - BRAZIL IP - 4 VI - 74 JC - GDB EM - 6904 PMID- 5304151 CU - 89 TT - Aspectos histologicos e function do figado na leptospirose ictero- hemorragica. SO - Hospital (Rio J) 1968 Oct;74(4):1125-48 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 69125400 AU - Khera SS TI - Zoonoses in India. LA - Eng MH - Animal MH - Brucellosis, Bovine/epidemiology MH - Cats MH - Cattle MH - Dogs MH - Escherichia coli Infections/epidemiology MH - Human MH - India MH - Leptospirosis/epidemiology MH - Rabies/epidemiology MH - Salmonella Infections, Animal/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 690416 DP - 1968 Oct IS - 0019-6479 TA - Indian Vet J PG - 811-5 CY - INDIA IP - 10 VI - 45 JC - GM9 EM - 6906 PMID- 4885958 CU - 90 SO - Indian Vet J 1968 Oct;45(10):811-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [79 medline neighbors] UI - 69114377 AU - Banker DD TI - Modern practice in immunization. 11. Other bacterial and miscellaneous vaccines. LA - Eng MH - Adult MH - Animal MH - Anthrax/prevention & control MH - Antivenins MH - *Bacterial Vaccines MH - Brucella Vaccine MH - Child MH - Common Cold/prevention & control MH - Dysentery, Bacillary/prevention & control MH - Human MH - Leprosy/prevention & control MH - Leptospirosis/prevention & control MH - Meningitis, Meningococcal/prevention & control MH - Mycoplasma Infections/prevention & control MH - Pneumonia/prevention & control MH - Pyrogens/therapeutic use MH - Snake Bites/prevention & control MH - Staphylococcal Vaccines MH - Tularemia/prevention & control MH - Viral Vaccines PT - JOURNAL ARTICLE PT - REVIEW DA - 690408 DP - 1968 Oct IS - 0019-5359 TA - Indian J Med Sci PG - 743-51 CY - INDIA IP - 10 VI - 22 JC - GJP EM - 6905 RF - 34 PMID- 4885471 CU - 90 SO - Indian J Med Sci 1968 Oct;22(10):743-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 70262203 AU - Reece WO AU - Hofstad MS AU - Swenson MJ TI - Establishment and maintenance of an SPF beagle dog colony. LA - Eng MH - Animal MH - *Animals, Laboratory MH - Ascariasis/diagnosis/prevention & control/veterinary MH - *Breeding MH - Cesarean Section MH - Disease Reservoirs/veterinary MH - Distemper/prevention & control MH - *Dogs MH - Environment MH - Female MH - Fetal Diseases/prevention & control/veterinary MH - Hepatitis, Animal/prevention & control MH - Leptospirosis/prevention & control/veterinary MH - Male MH - Methods MH - Parasitic Diseases/prevention & control/veterinary MH - Pregnancy MH - Quarantine MH - Viral Vaccines/therapeutic use PT - JOURNAL ARTICLE DA - 701002 DP - 1968 Oct IS - 0094-5331 TA - Lab Anim Care PG - 509-12 SB - M CY - UNITED STATES IP - 5 VI - 18 JC - BDU EM - 7011 PMID- 4247416 CU - 92 SO - Lab Anim Care 1968 Oct;18(5):509-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69141524 AU - Fuzi M AU - Csukas Z TI - [Ampicillin sensitivity of pathogenic Leptospira strains (preliminary report)] LA - Hun MH - Ampicillin/*pharmacology MH - Leptospira/*drug effects MH - *Penicillin Resistance PT - JOURNAL ARTICLE DA - 690508 DP - 1968 Sep 29 IS - 0030-6002 TA - Orv Hetil PG - 2147-8 CY - HUNGARY IP - 39 VI - 109 JC - OL8 EM - 6906 PMID- 5191493 CU - 87 TT - Pathogen leptospira torzsek ampicillin erzekenysege (elozetes kozlemeny) SO - Orv Hetil 1968 Sep 29;109(39):2147-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 70040110 AU - Calisto ML AU - Sindoni L AU - Frezza L TI - [Frequency of leptospiral infections in goats from the Province of Reggio Calabria] LA - Ita MH - Agglutination Tests MH - Animal MH - *Goats MH - Italy MH - Leptospira canicola MH - Leptospira interrogans MH - Leptospirosis/epidemiology/immunology/*veterinary PT - JOURNAL ARTICLE DA - 700109 DP - 1968 Sep-Oct IS - 0017-0267 TA - G Batteriol Virol Immunol PG - 291-4 SB - M CY - ITALY IP - 9 VI - 61 JC - FA5 EM - 7002 PMID- 5754009 CU - 88 TT - Frequenza di infezioni da leptospire in caprini provenienti dalla provincia di Reggio Calabria. SO - G Batteriol Virol Immunol 1968 Sep-Oct;61(9):291-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69115355 AU - Balaprakasam RA AU - Seshadri SJ TI - A study on the pathology of a case of "leptospiraemia" in a piglet. LA - Eng MH - Animal MH - Kidney/pathology MH - Leptospirosis/pathology/*veterinary MH - Liver/pathology MH - Lung/pathology MH - Lymph Nodes/pathology MH - Swine MH - Swine Diseases/*pathology PT - JOURNAL ARTICLE DA - 690408 DP - 1968 Sep IS - 0019-6479 TA - Indian Vet J PG - 720-5 CY - INDIA IP - 9 VI - 45 JC - GM9 EM - 6905 PMID- 5751660 CU - 85 SO - Indian Vet J 1968 Sep;45(9):720-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 69013009 AU - Prydie J TI - Studies with an attenuated canine distemper vaccine derived from chick embryo cultures. LA - Eng MH - Animal MH - Cytopathogenic Effect, Viral MH - Distemper Virus, Canine/*isolation & purification MH - Dog Diseases/immunology MH - Dogs MH - Hepatitis, Animal/immunology MH - Leptospirosis/immunology/veterinary MH - Neutralization Tests MH - Tissue Culture MH - *Viral Vaccines MH - *Virus Cultivation PT - JOURNAL ARTICLE DA - 681208 DP - 1968 Sep IS - 0034-5288 TA - Res Vet Sci PG - 443-52 SB - M CY - ENGLAND IP - 5 VI - 9 JC - R7D EM - 6901 PMID- 5693317 CU - 85 SO - Res Vet Sci 1968 Sep;9(5):443-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69012872 AU - Horsch F AU - Beer J TI - [Epizootiology of leptospirosis in swine in the German Democratic Republic] LA - Ger MH - *Abortion, Veterinary MH - Animal MH - Female MH - Germany, East MH - Leptospirosis/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 681208 DP - 1968 Sep 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 642-8 CY - GERMANY, EAST IP - 17 VI - 23 JC - NGV EM - 6901 PMID- 5693305 CU - 88 TT - Zur Epizootiologie der Leptospirose des Schweines in der DDR. SO - Monatsh Veterinarmed 1968 Sep 1;23(17):642-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68409107 AU - Fresh JW AU - Tsai CC AU - Lai CH AU - Chang CT TI - Leptospirosis in man and rodents on Taiwan. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Animal MH - Cattle MH - Child MH - Disease Reservoirs MH - Dogs MH - Female MH - Geography MH - Goats MH - Human MH - Leptospira/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis/*epidemiology/immunology/microbiology MH - Male MH - Rats MH - Rodent Diseases/*epidemiology MH - Taiwan PT - JOURNAL ARTICLE DA - 681103 DP - 1968 Sep IS - 0002-9637 TA - Am J Trop Med Hyg PG - 760-8 SB - A SB - M CY - UNITED STATES IP - 5 VI - 17 JC - 3ZQ EM - 6812 PMID- 5692123 CU - 88 SO - Am J Trop Med Hyg 1968 Sep;17(5):760-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68399656 AU - Finco DR AU - Low DG TI - Water, electrolyte, and acid-base alterations in experimental canine leptospirosis. LA - Eng MH - *Acid-Base Equilibrium MH - Animal MH - Bicarbonates/blood MH - Blood Urea Nitrogen MH - Body Fluids/analysis MH - Calcium/blood MH - Chlorides/analysis MH - Dog Diseases/*blood MH - Dogs MH - Hydrogen-Ion Concentration MH - Leptospirosis/blood/*veterinary MH - Muscles/analysis MH - Phosphorus/blood MH - Potassium/analysis MH - Sodium/analysis MH - *Water-Electrolyte Balance PT - JOURNAL ARTICLE DA - 681024 DP - 1968 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1799-807 SB - M CY - UNITED STATES IP - 9 VI - 29 JC - 40C EM - 6812 PMID- 5691747 CU - 85 SO - Am J Vet Res 1968 Sep;29(9):1799-807 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 68399663 AU - Reilly JR AU - Ferris DH AU - Hanson LE TI - Experimental demonstration of the enteric route of infection with Leptospira grippotyphosa in wild carnivores. LA - Eng MH - Animal MH - Capsules MH - *Carnivora MH - Cineradiography MH - Gastrointestinal System/radiography MH - Leptospirosis/immunology/microbiology/*veterinary PT - JOURNAL ARTICLE DA - 681024 DP - 1968 Sep IS - 0002-9645 TA - Am J Vet Res PG - 1849-54 SB - M CY - UNITED STATES IP - 9 VI - 29 JC - 40C EM - 6812 PMID- 5673518 SO - Am J Vet Res 1968 Sep;29(9):1849-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70090663 AU - Viatkin SK AU - Belousov ZF AU - Butuzov GM TI - [Leptospirosis of swine in Northern Kazakhstan District] LA - Rus MH - Animal MH - Kazakhstan MH - Leptospirosis/*veterinary MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 700305 DP - 1968 Sep IS - 0042-4846 TA - Veterinariia PG - 36-7 CY - USSR IP - 9 VI - 45 JC - XCC EM - 7004 PMID- 4243890 CU - 92 TT - Leptospiroz svinei v Severo-Kazakhstanskoi oblasti. SO - Veterinariia 1968 Sep;45(9):36-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 70090662 AU - Tutov IK TI - [Peculiarities of leptospirosis in animals in Stavropol Territory] LA - Rus MH - Animal MH - Animal Diseases/*diagnosis MH - Cattle MH - Cattle Diseases/diagnosis MH - Chickens MH - Dog Diseases/diagnosis MH - Dogs MH - Horse Diseases/diagnosis MH - Horses MH - Leptospirosis/diagnosis/*veterinary MH - Poultry Diseases/diagnosis MH - Rodent Diseases/diagnosis MH - Russia MH - Sheep MH - Sheep Diseases/diagnosis MH - Swine MH - Swine Diseases/diagnosis PT - JOURNAL ARTICLE DA - 700305 DP - 1968 Sep IS - 0042-4846 TA - Veterinariia PG - 35 CY - USSR IP - 9 VI - 45 JC - XCC EM - 7004 PMID- 4243889 CU - 92 TT - Osobennosti leptospiroza zhivotnykh v Stavropol'skom krae. SO - Veterinariia 1968 Sep;45(9):35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70032332 AU - Valova GP AU - Borisov VN AU - Vashkevich RB TI - [Experience in experimental infection of reindeer calves with leptospirosis] LA - Rus MH - Animal MH - Leptospira/*pathogenicity MH - Leptospirosis/*veterinary MH - *Reindeer MH - Siberia PT - JOURNAL ARTICLE DA - 700102 DP - 1968 Aug IS - 0042-4846 TA - Veterinariia PG - 33-5 CY - USSR IP - 8 VI - 45 JC - XCC EM - 7002 PMID- 5753963 CU - 85 TT - Opyt po zarazheniiu teliat severnykh olenei leptospirozom. SO - Veterinariia 1968 Aug;45(8):33-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70032331 AU - Bitiukov VA AU - Saidasheva SE AU - Missbakh GA AU - Savarovskaia OD TI - [Blood indices of calves in leptospirosis] LA - Rus MH - Animal MH - Blood Proteins/*analysis MH - Cattle MH - Cattle Diseases/*blood MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 700102 DP - 1968 Aug IS - 0042-4846 TA - Veterinariia PG - 33 CY - USSR IP - 8 VI - 45 JC - XCC EM - 7002 PMID- 5753962 CU - 85 TT - Pokazateli krovi u teliat pri leptospiroze. SO - Veterinariia 1968 Aug;45(8):33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 69236228 AU - Tonkonozhenko AP AU - Rumiantseva NI TI - [On the intra-uterine transmission of leptospirosis in small rodents] LA - Rus MH - Animal MH - Female MH - Leptospirosis/*etiology MH - Maternal-Fetal Exchange MH - Mice MH - Pregnancy MH - Rodentia PT - JOURNAL ARTICLE DA - 690902 DP - 1968 Aug TA - Zh Mikrobiol Epidemiol Immunobiol PG - 138 SB - M CY - USSR IP - 8 VI - 45 JC - Y9O EM - 6910 PMID- 5753477 CU - 89 TT - O vnutriutrobnoi peradache leptospiroza u melkikh gryzunov. SO - Zh Mikrobiol Epidemiol Immunobiol 1968 Aug;45(8):138 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70032333 AU - Iurkov GG AU - Andriian EA TI - [Swine as a source of pathogenic leptospira] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*etiology MH - *Disease Reservoirs MH - Leptospirosis/*veterinary MH - Swine MH - Swine Diseases/*microbiology MH - USSR PT - JOURNAL ARTICLE DA - 700102 DP - 1968 Aug IS - 0042-4846 TA - Veterinariia PG - 35-7 CY - USSR IP - 8 VI - 45 JC - XCC EM - 7002 PMID- 5736781 TT - Svin'i--istochnik patogennykh leptospir. SO - Veterinariia 1968 Aug;45(8):35-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [74 medline neighbors] UI - 68396676 AU - Steele JH TI - Occupational health in agriculture. Animal-borne diseases. LA - Eng MH - *Agricultural Workers' Diseases MH - Animal MH - Anthrax/epidemiology MH - Bird Diseases/epidemiology MH - Brucellosis/epidemiology MH - Coccidioidomycosis/epidemiology MH - Cryptococcosis/epidemiology MH - Glanders/epidemiology MH - Herpesviridae Infections/veterinary MH - Histoplasmosis/epidemiology MH - Horses MH - Human MH - Influenza/epidemiology MH - Leptospirosis/epidemiology MH - Occupational Diseases/*epidemiology MH - Parasitic Diseases/epidemiology MH - Rabies/epidemiology MH - Reoviridae Infections/veterinary MH - Respiratory Tract Infections/veterinary MH - Rickettsia Infections/epidemiology MH - Salmonella Infections/epidemiology MH - Sporotrichosis/epidemiology MH - Tetanus/epidemiology MH - Tinea/epidemiology MH - Tuberculosis/epidemiology MH - Tularemia/epidemiology MH - Virus Diseases/epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE PT - REVIEW DA - 681019 DP - 1968 Aug IS - 0003-9896 TA - Arch Environ Health PG - 267-85 SB - A SB - M CY - UNITED STATES IP - 2 VI - 17 JC - 6YO EM - 6812 RF - 53 PMID- 4299690 CU - 93 SO - Arch Environ Health 1968 Aug;17(2):267-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 70032330 AU - Soloshenko IZ AU - Semenova LP AU - Meleksetov MA TI - [Epizootiology of leptospirosis in animals in North Ossetian Autonomous Soviet Socialist Republic] LA - Rus MH - Animal MH - Animal Diseases/*epidemiology MH - Leptospirosis/*veterinary MH - Russia PT - JOURNAL ARTICLE DA - 700102 DP - 1968 Aug IS - 0042-4846 TA - Veterinariia PG - 31-2 CY - USSR IP - 8 VI - 45 JC - XCC EM - 7002 PMID- 4242617 CU - 92 TT - Epizootologiia leptospiroza zhivotnykh v Severo-Osetinskoi ASSR. SO - Veterinariia 1968 Aug;45(8):31-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69017183 AU - Mochmann H AU - Hergt R AU - Hager G AU - Ernst K TI - [5 individual cases of leptospirosis pomona in the German Democratic Republic] LA - Ger MH - Animal MH - English Abstract MH - Germany, East MH - Human MH - Leptospirosis/*diagnosis/etiology MH - Male MH - Middle Age MH - Swine MH - Zoonoses/diagnosis PT - JOURNAL ARTICLE DA - 681209 DP - 1968 Jul 18 IS - 0012-0219 TA - Dtsch Gesundheitsw PG - 1356-62 CY - GERMANY, EAST IP - 29 VI - 23 JC - ECG EM - 6901 PMID- 5693651 CU - 85 TT - Funf Einzelfalle von Leptospirosis pomona in der DDR. SO - Dtsch Gesundheitsw 1968 Jul 18;23(29):1356-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69003112 AU - Konrad J AU - Vosta J TI - [Observation of antibody titer against leptospirae in liver-and other internal diseases of horses] LA - Ger MH - Animal MH - *Antibodies MH - Horse Diseases/*immunology MH - Horses MH - Leptospirosis/*veterinary MH - Liver Diseases/*veterinary PT - JOURNAL ARTICLE DA - 681121 DP - 1968 Jul 15 IS - 0012-0847 TA - Dtsch Tierarztl Wochenschr PG - 347-52 CY - GERMANY, WEST IP - 14 VI - 75 JC - ECS EM - 6901 PMID- 5692821 CU - 85 TT - Das Verfolgen der Antikorpertiter gegen Leptospiren bei Hapatopathien und anderen inneren Krankheiten der Pferde. SO - Dtsch Tierarztl Wochenschr 1968 Jul 15;75(14):347-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68353535 AU - Kariks J AU - Stallman ND TI - Human leptospirosis, proven by culture, in the territory of Papua and New Guinea. LA - Eng MH - Adult MH - Case Report MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*diagnosis MH - Male MH - New Guinea PT - JOURNAL ARTICLE DA - 680913 DP - 1968 Jul 6 IS - 0025-729X TA - Med J Aust PG - 20 SB - M CY - AUSTRALIA IP - 1 VI - 2 JC - M26 EM - 6811 PMID- 5664425 SO - Med J Aust 1968 Jul 6;2(1):20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 68353533 AU - Morahan RJ TI - Isolation of leptospires in the tarassovi (Hyos) serogroup from a bandicoot (Marsupialia, peramelidae) from Koil Island, territory of Papua and New Guinea. LA - Eng MH - Agglutination Tests MH - Animal MH - Leptospira/*isolation & purification MH - Male MH - New Guinea MH - Rodentia PT - JOURNAL ARTICLE DA - 680913 DP - 1968 Jul 6 IS - 0025-729X TA - Med J Aust PG - 18-9 SB - M CY - AUSTRALIA IP - 1 VI - 2 JC - M26 EM - 6811 PMID- 5664424 SO - Med J Aust 1968 Jul 6;2(1):18-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69027313 AU - Bercovici C AU - Straton A AU - Teodorovici G AU - Straton C AU - Radulescu P AU - Ivan A AU - Besleaga V AU - Iosub C AU - Brebenel C AU - Buzdugan R AU - Buzdugan I AU - Dragoi G TI - [Research on leptospirosis in humans and domestic animals in the region of Moldovia in the years 1964-1967] LA - Rum MH - Animal MH - Antibodies/analysis MH - Cattle MH - *Cattle Diseases MH - Hemagglutination Tests MH - *Horse Diseases MH - Horses MH - Human MH - Leptospirosis/*epidemiology MH - Romania MH - Sheep MH - *Sheep Diseases MH - Swine MH - *Swine Diseases MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 681219 DP - 1968 Jul-Sep IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 693-701 CY - ROMANIA IP - 3 VI - 72 JC - SHP EM - 6902 PMID- 5693775 CU - 88 TT - Cercetari asupra leptospirozelor la om si animale domestice pe teritoriul Moldovei in anii 1964-1967. SO - Rev Med Chir Soc Med Nat Iasi 1968 Jul-Sep;72(3):693-701 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69005294 AU - Retzlaff N AU - Weise E TI - [Serologic, culture, and histological studies of cattle for slaughter for leptospirosis] LA - Ger MH - Agglutination Tests MH - Animal MH - Cattle MH - *Cattle Diseases MH - English Abstract MH - Leptospirosis/*veterinary MH - Microscopy, Fluorescence PT - JOURNAL ARTICLE DA - 681124 DP - 1968 Jul TA - Zentralbl Veterinarmed [B] PG - 581-91 CY - GERMANY, WEST IP - 5 VI - 15 JC - Y72 EM - 6901 PMID- 5692943 CU - 89 TT - Serologische, kulturelle und histologische Untersuchungen an Schlachtrindern auf Leptospirose. SO - Zentralbl Veterinarmed [B] 1968 Jul;15(5):581-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68400335 AU - Fennestad KL AU - Borg-Petersen C AU - Brummerstedt E TI - Leptospira antibody formation by porcine foetuses. LA - Eng MH - Animal MH - *Antibody Formation MH - Female MH - Fetal Death/immunology/*veterinary MH - Leptospira/*immunology MH - Leptospirosis/immunology/*veterinary MH - Pregnancy MH - *Pregnancy, Animal PT - JOURNAL ARTICLE DA - 681024 DP - 1968 Jul IS - 0034-5288 TA - Res Vet Sci PG - 378-80 SB - M CY - ENGLAND IP - 4 VI - 9 JC - R7D EM - 6812 PMID- 5691817 CU - 85 SO - Res Vet Sci 1968 Jul;9(4):378-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68364548 AU - Chung GT TI - Leptospiral infection of apprarently normal pigs. LA - Eng MH - Animal MH - Leptospira/classification/*isolation & purification MH - Leptospirosis/*veterinary MH - Serotyping MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 681005 DP - 1968 Jul IS - 0005-0423 TA - Aust Vet J PG - 315-9 SB - M CY - AUSTRALIA IP - 7 VI - 44 JC - 9IE EM - 6811 PMID- 5691269 CU - 85 SO - Aust Vet J 1968 Jul;44(7):315-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 68321823 AU - Stalheim OH TI - Vaccination of hamsters, swine, and cattle with viable, avirulent Leptospira pomona. LA - Eng MH - Abortion, Veterinary/*prevention & control MH - Animal MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Female MH - Fetal Death/prevention & control/*veterinary MH - Hamsters/*immunology MH - Kidney Diseases/veterinary MH - Leptospira/isolation & purification MH - Pregnancy MH - *Pregnancy, Animal MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 680829 DP - 1968 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1463-8 SB - M CY - UNITED STATES IP - 7 VI - 29 JC - 40C EM - 6810 PMID- 5690782 CU - 85 SO - Am J Vet Res 1968 Jul;29(7):1463-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69003472 AU - Brito T de TI - On the pathogenesis of the hepatic and renal lesions in leptospirosis. LA - Eng MH - Animal MH - Human MH - Kidney/*pathology MH - Leptospirosis/*pathology MH - Liver/*pathology PT - JOURNAL ARTICLE DA - 681121 DP - 1968 Jul-Aug IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 237-41 CY - BRAZIL IP - 4 VI - 10 JC - S9D EM - 6901 PMID- 5679658 SO - Rev Inst Med Trop Sao Paulo 1968 Jul-Aug;10(4):237-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [144 medline neighbors] UI - 68350319 AU - Sheeby TW TI - Digestive disease as a national problem. VI. Enteric disease among United States troops in Vietnam. LA - Eng MH - Cholera/epidemiology MH - Diarrhea/epidemiology MH - Dysentery, Bacillary/epidemiology MH - Gastrointestinal Diseases/*epidemiology MH - Giardiasis/epidemiology MH - Hepatitis A/epidemiology MH - Hookworm Infections/epidemiology MH - Human MH - Infection/epidemiology MH - Leptospirosis/epidemiology MH - Malaria/epidemiology MH - Male MH - *Military Medicine MH - Peptic Ulcer/epidemiology MH - Salmonella Infections/epidemiology MH - Sprue, Tropical/epidemiology MH - Strongyloidiasis/epidemiology MH - Vietnam PT - JOURNAL ARTICLE DA - 680913 DP - 1968 Jul IS - 0016-5085 TA - Gastroenterology PG - 105-12 SB - A SB - M CY - UNITED STATES IP - 1 VI - 55 JC - FH3 EM - 6811 PMID- 5663500 CU - 88 SO - Gastroenterology 1968 Jul;55(1):105-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68405355 AU - Sauvaget J TI - [The diagnosis of icterohemorrhagic leptospirosis] LA - Fre MH - Nursing MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE DA - 681101 DP - 1968 Jul-Sep IS - 0019-9613 TA - Infirm Fr PG - 4-8 SB - N CY - FRANCE IP - 97 JC - GOD EM - 6812 PMID- 5187495 CU - 87 LI - N TT - Diagnostic de la spirochetose ictero--hemorragique. SO - Infirm Fr 1968 Jul-Sep;(97):4-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68393012 AU - Sulzer CR AU - Harvey TW AU - Galton MM TI - Comparison of diagnostic technics for the detection of leptospirosis in rats. LA - Eng MH - *Agglutination Tests MH - Animal MH - Comparative Study MH - Culture Media MH - *Fluorescent Antibody Technique MH - Leptospirosis/*diagnosis MH - Rats MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 681015 DP - 1968 Jul IS - 0017-9035 TA - Health Lab Sci PG - 171-3 SB - M CY - UNITED STATES IP - 3 VI - 5 JC - G2C EM - 6812 PMID- 4876436 CU - 90 SO - Health Lab Sci 1968 Jul;5(3):171-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [22 medline neighbors] UI - 69093659 AU - Parnas J AU - Poplawski S AU - Cybulska MT AU - Ksiazek A TI - [Sugar units, chemotypes and serotypes of Leptospira] LA - Ger MH - Amino Sugars/metabolism MH - Culture Media MH - Hexoses/metabolism MH - Leptospira/*classification/metabolism MH - Leptospira canicola/*classification/metabolism MH - Leptospira interrogans/*classification/metabolism MH - Pentoses/metabolism MH - Serotyping MH - Uronic Acids/metabolism PT - JOURNAL ARTICLE DA - 690307 DP - 1968 Jul TA - Z Naturforsch B PG - 993-6 SB - M CY - GERMANY, WEST IP - 7 VI - 23 JC - BZ2 EM - 6904 PMID- 4387667 CU - 94 TT - Zuckerbausteine, Chemotypen und Serotypen der Leptospiren. SO - Z Naturforsch B 1968 Jul;23(7):993-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69005646 AU - Kadlcik K AU - Vosta J AU - Polednikova I AU - Vychodil J TI - [Results of studies on tick encephalitis and leptospirosis in their natural foci] LA - Cze MH - Czechoslovakia MH - Encephalitis, Tick-Borne/*epidemiology MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 681125 DP - 1968 Jul IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 244-8 CY - CZECHOSLOVAKIA IP - 4 VI - 17 JC - CSH EM - 6901 PMID- 4234535 CU - 92 TT - Vysledky vyzkumu prirodniho ohniska klistove encefalitidy a leptospirozy. SO - Cesk Epidemiol Mikrobiol Imunol 1968 Jul;17(4):244-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 68312865 AU - Sitprija V TI - Renal involvement in human leptospirosis. LA - Eng MH - Adult MH - Aminohippuric Acids/diagnostic use MH - Blood Urea Nitrogen MH - Blood Volume MH - Creatinine/blood/urine MH - Dehydration/complications MH - Female MH - Human MH - Kidney/*physiopathology MH - Kidney Concentrating Ability MH - Kidney Failure, Acute/blood/complications MH - Kidney Function Tests MH - Leptospirosis/complications/*physiopathology MH - Male MH - Middle Age MH - Sodium/urine MH - Urea/urine MH - Uremia/etiology PT - JOURNAL ARTICLE DA - 680816 DP - 1968 Jun 15 IS - 0007-1447 TA - Br Med J PG - 656-8 SB - A SB - M CY - ENGLAND IP - 606 VI - 2 JC - B4W EM - 6810 PMID- 5658409 SO - Br Med J 1968 Jun 15;2(606):656-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69001236 AU - Parnas J AU - Mierzejewska I AU - Cybulska MT AU - Radominska I TI - [Human leptospirosis polonica, a new clinical and serological form] LA - Ger MH - English Abstract MH - Human MH - Leptospira/classification MH - Leptospirosis/*epidemiology MH - Serotyping PT - JOURNAL ARTICLE DA - 681120 DP - 1968 Jun 6 IS - 0012-0219 TA - Dtsch Gesundheitsw PG - 1092-5 CY - GERMANY, EAST IP - 23 VI - 23 JC - ECG EM - 6901 PMID- 5678855 CU - 88 TT - Erkrankung des Menschen an Leptospirosis polonica, einer neuen klinisch- serologicchen Form. SO - Dtsch Gesundheitsw 1968 Jun 6;23(23):1092-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70133736 AU - Shor EM AU - Khaimzon BI TI - [Differential diagnosis between tick borne encephalitis and anicteric leptospirosis] LA - Rus MH - Diagnosis, Differential MH - Encephalitis, Tick-Borne/*diagnosis MH - Female MH - Human MH - Leptospirosis/*diagnosis MH - Male PT - JOURNAL ARTICLE DA - 700422 DP - 1968 Jun IS - 0038-5077 TA - Sov Med PG - 113-6 CY - USSR IP - 6 VI - 31 JC - UW7 EM - 7006 PMID- 5741579 TT - O differentisial'noi diagnostike mezhdu kleshchevym entsefalitom i bezzheltushnym leptospirozom. SO - Sov Med 1968 Jun;31(6):113-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 69226234 AU - Aguzarova MKh AU - Bondarev AI TI - [The role of water as a factor in the spread of leptospirosis in North Osetian ASSR] LA - Rus MH - Adolescence MH - Child MH - Child, Preschool MH - English Abstract MH - Human MH - Leptospirosis/epidemiology/*etiology MH - USSR MH - *Water Microbiology MH - Water Supply PT - JOURNAL ARTICLE DA - 690819 DP - 1968 Jun IS - 0016-9900 TA - Gig Sanit PG - 13-6 CY - USSR IP - 6 VI - 33 JC - FPZ EM - 6910 PMID- 5730377 CU - 88 TT - Rol' vodnogo faktora v rasprostranenii leptospirozov v Serevo- Osetinskoi ASSR. SO - Gig Sanit 1968 Jun;33(6):13-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 69092661 AU - Shifrin IA AU - Osatilovskaia RIa AU - Shuruntaeva RV TI - [The microagglutination reaction with killed eptospira diagnosticum] LA - Rus MH - *Agglutination Tests MH - Emulsions MH - *Leptospira MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 690307 DP - 1968 Jun IS - 0300-9114 TA - Voen Med Zh PG - 53-5 CY - USSR VI - 6 JC - XGS EM - 6904 PMID- 5706307 TT - Reaktsiia mikroaggliutinatsii s ubitym leptospiroznym diagnostikumom. SO - Voen Med Zh 1968 Jun;6:53-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68368741 AU - Yanagihara Y AU - Mifuchi I TI - Microfibers present in surface structure of Leptospira. LA - Eng MH - Leptospira/*cytology MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 681007 DP - 1968 Jun IS - 0021-9193 TA - J Bacteriol PG - 2403-6 SB - M CY - UNITED STATES IP - 6 VI - 95 JC - HH3 EM - 6811 PMID- 5669911 SO - J Bacteriol 1968 Jun;95(6):2403-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 68368730 AU - Anderson DL AU - Johnson RC TI - Electron microscopy of immune disruption of leptospires: action of complement and lysozyme. LA - Eng MH - Animal MH - Cell Membrane MH - Cell Wall MH - Complement/*pharmacology MH - Immune Sera/*pharmacology MH - Leptospira/drug effects/*immunology MH - Leptospira canicola/drug effects/immunology MH - Microscopy, Electron MH - Muramidase/*pharmacology MH - Rabbits PT - JOURNAL ARTICLE DA - 681007 DP - 1968 Jun IS - 0021-9193 TA - J Bacteriol PG - 2293-309 SB - M CY - UNITED STATES IP - 6 VI - 95 JC - HH3 EM - 6811 PMID- 5669901 SO - J Bacteriol 1968 Jun;95(6):2293-309 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 69053382 AU - Yanagihara Y AU - Mifuchi I TI - Studies on pathogenic leptospirae. VI. Effect of tween 80 on the growth of Leptospira canicola and Leptospira icterohaemorrhagiae. LA - Eng MH - Bacteriological Techniques MH - Leptospira canicola/*growth & development MH - Leptospira interrogans/*growth & development MH - Surface-Active Agents/*pharmacology PT - JOURNAL ARTICLE DA - 690125 DP - 1968 Jun IS - 0021-5139 TA - Jpn J Microbiol PG - 145-9 SB - M CY - JAPAN IP - 2 VI - 12 JC - KMF EM - 6903 PMID- 4881257 CU - 90 SO - Jpn J Microbiol 1968 Jun;12(2):145-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 69184585 AU - Pevzner IN AU - Drankina DI TI - [On a study of the natural focality of leptospirosis in Mordva ASSR] LA - Rus MH - Agricultural Workers' Diseases/*epidemiology MH - Animal MH - Disease Reservoirs MH - Human MH - Leptospirosis/*epidemiology MH - Russia PT - JOURNAL ARTICLE DA - 690629 DP - 1968 Jun TA - Zh Mikrobiol Epidemiol Immunobiol PG - 156 SB - M CY - USSR IP - 6 VI - 45 JC - Y9O EM - 6908 PMID- 4238819 CU - 92 TT - K izucheniiu prirodnoi ochagovosti leptospirozov v mordovskoi ASSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1968 Jun;45(6):156 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 69039846 AU - Sorensen FH AU - Ingemar K AU - Skjoldborg H TI - [Leptospirosis icterohaemorrhagica with severe azotemia] LA - Dan MH - Adult MH - Hemodialysis MH - Human MH - Male MH - Middle Age MH - Myocardial Diseases MH - Urea/blood MH - Uremia/*etiology MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 690110 DP - 1968 May 30 IS - 0041-5782 TA - Ugeskr Laeger PG - 934-6 CY - DENMARK IP - 22 VI - 130 JC - WM8 EM - 6902 PMID- 5699686 TT - Leptospirosis icterohaemorrhagica med svaer azotaemi. SO - Ugeskr Laeger 1968 May 30;130(22):934-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 68245720 AU - Baldelli B TI - [Leptospira and leptospirosis in man and animals] LA - Ita MH - Animal MH - Cattle MH - Cattle Diseases MH - Dog Diseases MH - Dogs MH - Human MH - Leptospira MH - Leptospirosis/*epidemiology/*veterinary MH - Swine MH - Swine Diseases PT - JOURNAL ARTICLE DA - 680710 DP - 1968 May 5 IS - 0026-4806 TA - Minerva Med PG - 2139-40 SB - M CY - ITALY IP - 36 VI - 59 JC - N6M EM - 6808 PMID- 5689974 CU - 88 TT - Leptospire e leptospirosi dell'uomo e degli animali. SO - Minerva Med 1968 May 5;59(36):2139-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68406603 AU - Sramkova L AU - Vanista J AU - Tesarova J TI - [On the clinical picture of leptospiroses] LA - Ger MH - Adolescence MH - Adult MH - Animal MH - Child MH - Diagnosis, Differential MH - Female MH - Human MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*diagnosis/microbiology MH - Male MH - Middle Age MH - Septicemia/diagnosis MH - Weil's Disease/*diagnosis/microbiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 681101 DP - 1968 May 3 IS - 0027-2973 TA - Munch Med Wochenschr PG - 1127-9 SB - M CY - GERMANY, WEST IP - 18 VI - 110 JC - MMW EM - 6812 PMID- 5695546 CU - 86 TT - Zum klinischen Bild der Leptospirosen. SO - Munch Med Wochenschr 1968 May 3;110(18):1127-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 70155251 AU - Parnas J AU - Cybulska MT AU - Mierejewska I AU - Radominska I TI - [The microbiological characteristics of Leptospira polonica and the clinical picture of human Leptospirosis "polonica"] LA - Ger MH - Amino Acids/analysis MH - Animal MH - Carbohydrates/analysis MH - Diagnosis, Differential MH - English Abstract MH - Human MH - Infrared Rays MH - Leptospira/analysis/*classification/enzymology/pathogenicity MH - Leptospirosis/blood/diagnosis/enzymology/*epidemiology MH - Poland MH - Serodiagnosis MH - Serotyping MH - Spectrophotometry MH - Zoonoses PT - JOURNAL ARTICLE DA - 700519 DP - 1968 May TA - Zentralbl Bakteriol [Orig] PG - 530-41 SB - M CY - GERMANY, WEST IP - 4 VI - 206 JC - Y4Y EM - 7007 PMID- 5754396 CU - 89 TT - Die mikrobiologische Charakteristik der Leptospira polonica und die Leptospirosis polonica des Menschen. SO - Zentralbl Bakteriol [Orig] 1968 May;206(4):530-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69297149 TI - [World Health Organization: current problems in leptospirosis research. (Report of a WHO expert group)] LA - Mul MH - Animal MH - Human MH - Leptospirosis/immunology/*veterinary MH - World Health Organization PT - JOURNAL ARTICLE DA - 691105 DP - 1968 May-Jun IS - 0300-9823 TA - Bull Off Int Epizoot PG - 866-89 CY - FRANCE IP - 5 VI - 69 JC - BR4 EM - 6912 PMID- 5753805 CU - 85 NI - A SO - Bull Off Int Epizoot 1968 May-Jun;69(5):866-89 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69297146 AU - Illartein PR TI - [Contribution to the study of the biology of Leptospira icterohaemorrhagiae. Experimental studies on the bacteriologic diagnosis of leptospiroses in animals] LA - Fre MH - Animal MH - Guinea Pigs MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/*veterinary MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 691105 DP - 1968 May-Jun IS - 0300-9823 TA - Bull Off Int Epizoot PG - 761-73 CY - FRANCE IP - 5 VI - 69 JC - BR4 EM - 6912 PMID- 5735240 TT - Contribution a l'etude de la biologie du Leptospire de l'ictere hemorragique. Recherches experimentales sur le diagnostic bacteriologique des leptospiroses chez l'animal. SO - Bull Off Int Epizoot 1968 May-Jun;69(5):761-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [155 medline neighbors] UI - 70179937 AU - Muller F AU - Ksivanek-Skrabalo L TI - [A study of fixed and soluble Leptospira antigens] LA - Ger MH - Agar MH - Animal MH - *Antigens MH - Complement Fixation Tests MH - English Abstract MH - Fluorescent Antibody Technique MH - Immune Sera MH - Immunodiffusion MH - Leptospira interrogans/drug effects/*immunology MH - Phenols/pharmacology MH - Rabbits MH - Solubility PT - JOURNAL ARTICLE DA - 700619 DP - 1968 May TA - Zentralbl Bakteriol [Orig] PG - 69-74 SB - M CY - GERMANY, WEST IP - 1 VI - 207 JC - Y4Y EM - 7008 PMID- 4986181 CU - 91 TT - Untersuchungen an gebundenen und loslichen Leptospiren-Antigenen. SO - Zentralbl Bakteriol [Orig] 1968 May;207(1):69-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70179938 AU - Burger G AU - Fuchs GH TI - [The sensitivity of indirect immunofluorescent staining in leptospirosis serodiagnosis] LA - Ger MH - Agglutination Tests MH - Animal MH - Cattle MH - Comparative Study MH - Complement Fixation Tests MH - Diagnosis, Differential MH - English Abstract MH - *Fluorescent Antibody Technique MH - Immune Sera MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 700619 DP - 1968 May TA - Zentralbl Bakteriol [Orig] PG - 74-82 SB - M CY - GERMANY, WEST IP - 1 VI - 207 JC - Y4Y EM - 7008 PMID- 4910114 CU - 90 TT - Zur empfindlichkeit der indirekten Immunofluoreszenzfarbung in der Leptospirose-Serodiagnostik. SO - Zentralbl Bakteriol [Orig] 1968 May;207(1):74-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 69037293 AU - Iorio A AU - Savino A AU - Zavka Nenci C TI - [Study of the cytopathic effect on primary cultures of mouse embryo liver and on a cell line in continuous culture of the same nature, caused by a strain of Leptospira icterohaemorrhagiae] LA - Ita MH - Animal MH - Embryo MH - In Vitro MH - *Leptospira interrogans MH - *Liver MH - Mice MH - *Tissue Culture PT - JOURNAL ARTICLE DA - 690109 DP - 1968 Apr 30 IS - 0037-8771 TA - Boll Soc Ital Biol Sper PG - 795-6 SB - M CY - ITALY IP - 8 VI - 44 JC - ALS EM - 6902 PMID- 5748880 CU - 85 TT - Studio sull'effetto citopatico su culture primarie di fegato di embrione di topo e su una linea cellulare in cultura continua della stessa natura da parte di un ceppo di Leptospira ictero-haemorrhagiae. SO - Boll Soc Ital Biol Sper 1968 Apr 30;44(8):795-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 69037292 AU - Savino A AU - Zavka Nenci C TI - [Sensitivity to penicillin of a strain of Leptospira ictero- haemorrhagiae cultured in various culture media] LA - Ita MH - Culture Media/*pharmacology MH - Leptospira interrogans/*drug effects MH - Penicillin Resistance MH - Penicillins/*pharmacology PT - JOURNAL ARTICLE DA - 690109 DP - 1968 Apr 30 IS - 0037-8771 TA - Boll Soc Ital Biol Sper PG - 792-5 SB - M CY - ITALY IP - 8 VI - 44 JC - ALS EM - 6902 PMID- 5698523 TT - Sensibilita alla penicillina di un ceppo di Leptospira ictero- haemorrhagiae coltivato in differenti terreni di cultura. SO - Boll Soc Ital Biol Sper 1968 Apr 30;44(8):792-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 70201646 AU - Ulendeev AI AU - Stepochkin AP TI - [Preventive vaccinations against hog cholera, erysipelas and leptospirosis in swine] LA - Rus MH - Animal MH - Erysipelothrix Infections/*prevention & control MH - Hog Cholera/*prevention & control MH - Leptospirosis/*veterinary MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/*veterinary PT - JOURNAL ARTICLE DA - 700717 DP - 1968 Apr IS - 0042-4846 TA - Veterinariia PG - 37-8 CY - USSR IP - 4 VI - 45 JC - XCC EM - 7009 PMID- 5754527 CU - 85 TT - Predokhranitel'nye privivki protiv chumy, rozhi i eptospiroza svinei. SO - Veterinariia 1968 Apr;45(4):37-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70201645 AU - Kir'ianov EA TI - [Leptospirosis in cattle caused by Leptospira bataviae] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - *Leptospira MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 700717 DP - 1968 Apr IS - 0042-4846 TA - Veterinariia PG - 36 CY - USSR IP - 4 VI - 45 JC - XCC EM - 7009 PMID- 5754526 CU - 85 TT - Leptospiroz krupnogo rogatogo skota, vyzvannyi Leptospira bataviae. SO - Veterinariia 1968 Apr;45(4):36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70201644 AU - Shimkus KA TI - [The occurrence of leptospirosis in the Lithuanian SSR] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/*veterinary MH - Lithuania MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 700717 DP - 1968 Apr IS - 0042-4846 TA - Veterinariia PG - 35-6 CY - USSR IP - 4 VI - 45 JC - XCC EM - 7009 PMID- 5754525 CU - 88 TT - Rasprostranenie leptospiroza v Litovskoi SSR. SO - Veterinariia 1968 Apr;45(4):35-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69297943 AU - Kiktenko VS AU - Levina LF TI - [A study of the effect of immune serum on leptospirae in the agglutination--lysis reaction] LA - Rus MH - *Agglutination Tests MH - Animal MH - Antigen-Antibody Reactions MH - *Complement MH - English Abstract MH - Immune Sera/*pharmacology MH - Leptospira/*drug effects MH - Leptospirosis/diagnosis MH - Methods MH - Microscopy, Electron MH - Rabbits PT - JOURNAL ARTICLE DA - 691105 DP - 1968 Apr TA - Zh Mikrobiol Epidemiol Immunobiol PG - 44-7 SB - M CY - USSR IP - 4 VI - 45 JC - Y9O EM - 6912 PMID- 5735287 CU - 90 TT - Izuchenie deistviia immunnoi syvorotki na leptospir v reaktsii aggliutinatsii-lizisa. SO - Zh Mikrobiol Epidemiol Immunobiol 1968 Apr;45(4):44-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69297932 AU - Vysotskii BV AU - Malykh FS AU - Abramov VK TI - [Leptospirosis among muskrats in the Primorsk region] LA - Rus MH - Animal MH - Human MH - Leptospirosis/*epidemiology/etiology MH - Rodent Diseases/*epidemiology/etiology MH - Siberia PT - JOURNAL ARTICLE DA - 691105 DP - 1968 Apr TA - Zh Mikrobiol Epidemiol Immunobiol PG - 139 SB - M CY - USSR IP - 4 VI - 45 JC - Y9O EM - 6912 PMID- 5735284 CU - 89 TT - Leptospiroz ondatr v Primorskom krae. SO - Zh Mikrobiol Epidemiol Immunobiol 1968 Apr;45(4):139 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 69296443 AU - Calonghi GF AU - Sueri L TI - [A case of leptospiral meningitis with positive serodiagnosis of toxoplasmosis] LA - Ita MH - Adolescence MH - Electroencephalography MH - Human MH - *Leptospira interrogans MH - Leptospirosis/*complications MH - Male MH - Meningococcal Infections/*complications MH - Serodiagnosis MH - Toxoplasmosis/*complications PT - JOURNAL ARTICLE DA - 691105 DP - 1968 Apr IS - 0017-0321 TA - G Mal Infett Parassit PG - 368-71 CY - ITALY IP - 4 VI - 20 JC - FD7 EM - 6912 PMID- 5735142 TT - Osservazioni su di un caso di meningite leptospirosica con sierodiagnosi positiva per toxoplasmosi. SO - G Mal Infett Parassit 1968 Apr;20(4):368-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 68245867 TI - Problems in leptospirosis. LA - Eng MH - Animal MH - Disease Reservoirs MH - Disease Vectors MH - *Leptospirosis PT - JOURNAL ARTICLE DA - 680710 DP - 1968 Apr IS - 0042-9694 TA - WHO Chron PG - 159-61 CY - SWITZERLAND IP - 4 VI - 22 JC - XNQ EM - 6808 PMID- 5689982 CU - 85 NI - A SO - WHO Chron 1968 Apr;22(4):159-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 68245871 AU - Ellinghausen HC Jr TI - Cultural and biochemical characteristics of a leptospire from frog kidney. LA - Eng MH - Animal MH - Anura MH - Glucose/pharmacology MH - Kidney/microbiology MH - Leptospira/drug effects/*growth & development/isolation & purification MH - Oxygen Consumption MH - Temperature MH - Thiamine/pharmacology MH - Vitamin B 12/pharmacology PT - JOURNAL ARTICLE DA - 680710 DP - 1968 Apr IS - 0043-5465 TA - Wildl Dis PG - 41-50 CY - UNITED STATES IP - 2 VI - 4 JC - XPC EM - 6808 PMID- 5651908 SO - Wildl Dis 1968 Apr;4(2):41-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [136 medline neighbors] UI - 68200533 AU - Azuma I AU - Yamamura Y AU - Yanagihara Y AU - Mifuchi I TI - Effect of mycolic acid and its derivatives on the growth of Leptospira icterohaemorrhagiae. LA - Eng MH - Culture Media MH - Fatty Acids/analysis/*pharmacology MH - Leptospira interrogans/*drug effects/growth & development MH - Lipids/pharmacology MH - Mycobacterium/analysis MH - Polysaccharides, Bacterial/pharmacology PT - JOURNAL ARTICLE DA - 680607 DP - 1968 Apr IS - 0021-9193 TA - J Bacteriol PG - 1489-90 SB - M CY - UNITED STATES IP - 4 VI - 95 JC - HH3 EM - 6807 PMID- 5646632 SO - J Bacteriol 1968 Apr;95(4):1489-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68232129 AU - Allen GL AU - Weber DR AU - Russell PK TI - The clinical picture of leptospirosis in American soldiers in Vietnam. LA - Eng MH - Adult MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - *Military Medicine MH - United States MH - Vietnam PT - JOURNAL ARTICLE DA - 680628 DP - 1968 Apr IS - 0026-4075 TA - Mil Med PG - 275-80 CY - UNITED STATES IP - 4 VI - 133 JC - N1A EM - 6808 PMID- 4967463 CU - 91 SO - Mil Med 1968 Apr;133(4):275-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 68271845 AU - Wooley RE AU - Vaneseltine WP TI - Nutritional requirements of Leptospirae. IV. Vitamin requirements of Leptospira pomona and its growth in a minimal medium. LA - Eng MH - Bacteriological Techniques MH - Culture Media MH - Leptospira/growth & development/*metabolism MH - Thiamine/metabolism MH - Vitamin B 12/metabolism MH - Vitamins/*metabolism PT - JOURNAL ARTICLE DA - 680719 DP - 1968 Apr IS - 0022-1899 TA - J Infect Dis PG - 206-14 SB - A SB - M CY - UNITED STATES IP - 2 VI - 118 JC - IH3 EM - 6809 PMID- 4870972 CU - 90 SO - J Infect Dis 1968 Apr;118(2):206-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 68271844 AU - Phibbs PV Jr AU - Vaneseltine WP TI - Nutritional requirements of Leptospirae. 3. Minimal nitrogen requirements of a strain of Leptospira pomona. LA - Eng MH - Amino Acids/metabolism MH - Ammonium Compounds MH - Bacteriological Techniques MH - Culture Media MH - Leptospira/growth & development/*metabolism MH - Nitrogen/*metabolism PT - JOURNAL ARTICLE DA - 680719 DP - 1968 Apr IS - 0022-1899 TA - J Infect Dis PG - 197-205 SB - A SB - M CY - UNITED STATES IP - 2 VI - 118 JC - IH3 EM - 6809 PMID- 4870971 CU - 90 SO - J Infect Dis 1968 Apr;118(2):197-205 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68232659 AU - Hirschberg N AU - Galton MM AU - Sulzer CR TI - Experiences with the indirect fluorescent antibody test in the serodiagnosis of leptospirosis. LA - Eng MH - Age Factors MH - Diagnosis, Laboratory MH - *Fluorescent Antibody Technique MH - Human MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 680629 DP - 1968 Apr IS - 0017-9035 TA - Health Lab Sci PG - 89-94 SB - M CY - UNITED STATES IP - 2 VI - 5 JC - G2C EM - 6808 PMID- 4869689 CU - 90 SO - Health Lab Sci 1968 Apr;5(2):89-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70201643 AU - Nuikin IaV TI - [Peculiarities of incidence of leptospirosis in animals in Moscow District] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/*veterinary MH - Russia MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 700717 DP - 1968 Apr IS - 0042-4846 TA - Veterinariia PG - 32-4 CY - USSR IP - 4 VI - 45 JC - XCC EM - 7009 PMID- 4246094 CU - 92 TT - Osobennosti rasprostraneniia leptospiroza zhivotnykh v Moskovskoi oblasti. SO - Veterinariia 1968 Apr;45(4):32-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 68399805 AU - Ryu E AU - Liu CK TI - Studies on the susceptibility of water buffaloes to Leptospira. LA - Eng MH - Age Factors MH - Animal MH - Antibody Formation MH - *Buffaloes MH - Female MH - Hemagglutination Tests MH - Leptospira/isolation & purification/*pathogenicity MH - Leptospira canicola/pathogenicity MH - Leptospirosis/immunology/veterinary MH - Male MH - Taiwan MH - Tissue Culture MH - Virus Cultivation PT - JOURNAL ARTICLE DA - 681024 DP - 1968 Apr IS - 0316-5957 TA - Can J Comp Med Vet Sci PG - 447-9 SB - M CY - CANADA IP - 2 VI - 32 JC - BCY EM - 6812 PMID- 4233835 CU - 92 SO - Can J Comp Med Vet Sci 1968 Apr;32(2):447-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [114 medline neighbors] UI - 68399800 AU - Boulanger P AU - Gray DP AU - Gibbs HC AU - Murphy DA TI - A serological survey of sera from domestic animals on Easter Island. LA - Eng MH - Animal MH - Antigen-Antibody Reactions MH - Brucellosis, Bovine/epidemiology MH - Cattle MH - Cattle Diseases/*epidemiology MH - Complement Fixation Tests/veterinary MH - Leptospirosis/epidemiology/veterinary MH - Ornithosis/epidemiology MH - Paratuberculosis/epidemiology MH - Polynesia MH - Q Fever/epidemiology/veterinary MH - Serodiagnosis/veterinary MH - Sheep MH - Sheep Diseases/*epidemiology MH - Stomatitis/epidemiology/veterinary MH - Swine MH - Swine Diseases/epidemiology MH - Tuberculosis, Bovine/epidemiology PT - JOURNAL ARTICLE DA - 681024 DP - 1968 Apr IS - 0316-5957 TA - Can J Comp Med Vet Sci PG - 425-9 SB - M CY - CANADA IP - 2 VI - 32 JC - BCY EM - 6812 PMID- 4233830 CU - 92 SO - Can J Comp Med Vet Sci 1968 Apr;32(2):425-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 70258356 AU - Queneau P AU - Levrat R AU - Detry R AU - Pont M TI - [Ictero-hemorrhagic isolated broncho-pulmonary leptospirosis (apropos of a new case)] LA - Fre MH - Adult MH - Bronchial Diseases MH - Bronchoscopy MH - Hemoptysis/etiology MH - Human MH - *Leptospira interrogans MH - *Lung Diseases MH - Male MH - Occupational Diseases MH - Serodiagnosis MH - *Weil's Disease PT - JOURNAL ARTICLE DA - 700928 DP - 1968 Mar 31 TA - Lyon Med PG - 1079-88 CY - FRANCE IP - 13 VI - 219 JC - LAI EM - 7011 PMID- 5745991 CU - 89 TT - Leptospirose ictero-hemorragique a forme broncho-pulmonaire isolee (a propos d'une nouvelle observation) SO - Lyon Med 1968 Mar 31;219(13):1079-88 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70090605 AU - Suleimanov SM TI - [Changes in lymph nodes of cattle in leptospirosis] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*pathology MH - Leptospirosis/*veterinary MH - Lymph Nodes/*pathology PT - JOURNAL ARTICLE DA - 700305 DP - 1968 Mar IS - 0042-4846 TA - Veterinariia PG - 39-40 CY - USSR IP - 3 VI - 45 JC - XCC EM - 7004 PMID- 5754185 CU - 85 TT - Izmeneniia v limfaticheskikh uzlakh krupnogo rogatogo skota pri leptospiroze. SO - Veterinariia 1968 Mar;45(3):39-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69279064 AU - Jindrichova J TI - [Leptospirosis risk in swine breeding] LA - Ger MH - Abattoirs MH - Agricultural Workers' Diseases/*epidemiology MH - Animal MH - Czechoslovakia MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology/*veterinary MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 691017 DP - 1968 Mar IS - 0049-8610 TA - Z Gesamte Hyg PG - 207-10 CY - GERMANY, EAST IP - 3 VI - 14 JC - XUO EM - 6912 PMID- 5753713 CU - 88 TT - Das Leptospirosenrisiko in der Schweinezucht. SO - Z Gesamte Hyg 1968 Mar;14(3):207-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69102757 AU - Brzyk T AU - Parnas J TI - [The allergic intracutaneous test in leptospirosis with leptospirin P] LA - Ger MH - Agglutination Tests MH - Animal MH - *Antigens/isolation & purification MH - Comparative Study MH - Dog Diseases/diagnosis MH - Dogs MH - Human MH - *Hypersensitivity, Delayed MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*diagnosis/veterinary MH - Skin Tests MH - Swine MH - Swine Diseases/diagnosis PT - JOURNAL ARTICLE DA - 690318 DP - 1968 Mar TA - Zentralbl Bakteriol [Orig] PG - 272-5 SB - M CY - GERMANY, WEST IP - 2 VI - 206 JC - Y4Y EM - 6905 PMID- 5751122 CU - 89 TT - Die allergische Intrakutanprobe bei Leptospirose mit Leptospirin P. SO - Zentralbl Bakteriol [Orig] 1968 Mar;206(2):272-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 69212319 AU - Kats LN AU - Konstantinova ND AU - Anan'in VV TI - [Various features of the submicroscopic structure of the cytoplasmic cylinder in leptospira] LA - Rus MH - Cell Nucleus MH - Cytoplasm MH - *Cytoplasmic Granules MH - Leptospira/analysis/*cytology/drug effects MH - Microscopy, Electron MH - Polysaccharides, Bacterial MH - Ribonucleases MH - RNA/analysis PT - JOURNAL ARTICLE DA - 690804 DP - 1968 Mar TA - Zh Mikrobiol Epidemiol Immunobiol PG - 64-7 SB - M CY - USSR IP - 3 VI - 45 JC - Y9O EM - 6909 PMID- 5729701 CU - 89 TT - Nekotorye osobennosti submikroskopicheskoi struktury tsitoplazmaticheskogo tsilindra u leptospir. SO - Zh Mikrobiol Epidemiol Immunobiol 1968 Mar;45(3):64-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69092975 AU - Sturdza N AU - Roman V AU - Nicolescu M AU - Alamita E AU - Borsai L TI - Human leptospirosis in Romania (1962-1966). LA - Eng MH - Abortion MH - Adolescence MH - Adult MH - Child MH - Child, Preschool MH - Female MH - Human MH - Leptospirosis/blood/*epidemiology MH - Male MH - Middle Age MH - Pregnancy MH - Romania PT - JOURNAL ARTICLE DA - 690307 DP - 1968 Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 63-74 CY - ROMANIA IP - 1 VI - 27 JC - 8EM EM - 6904 PMID- 5706452 CU - 88 SO - Arch Roum Pathol Exp Microbiol 1968 Mar;27(1):63-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69092965 AU - Topciu V AU - Spinu I AU - Trinh-Thi-Hang-Quy TI - [Efficiency of bacteriological methods used in the diagnosis of human leptospirosis in the course of an epidemic] LA - Fre MH - Animal MH - Disease Outbreaks MH - Guinea Pigs MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/blood/*diagnosis/urine PT - JOURNAL ARTICLE DA - 690307 DP - 1968 Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 183-92 CY - ROMANIA IP - 1 VI - 27 JC - 8EM EM - 6904 PMID- 5706445 TT - Efficience des methodes bacteriologiques ulilisees dans le diagnostic de la leptospirose humaine, au cours d'un epidemique. SO - Arch Roum Pathol Exp Microbiol 1968 Mar;27(1):183-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68367682 AU - Sofletea I AU - Silvas D AU - Oltean M AU - Ronea A TI - [Incidence of leptospirosis in swine and cattle in the districts of Mures and Harghita] LA - Rum MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Leptospirosis/*veterinary MH - Romania MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 681006 DP - 1968 Mar-Apr IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 153-6 CY - ROMANIA IP - 2 VI - 13 JC - MXQ EM - 6811 PMID- 5691354 CU - 88 TT - Incidenta leptospirozei la porcine si bovine in judetele Mures si Harghita. SO - Microbiol Parazitol Epidemiol (Bucur) 1968 Mar-Apr;13(2):153-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 68401550 AU - Perrault M AU - Dry J AU - Corvol P AU - Debray M TI - [Anemia due to deficiency of glucose-6-phospahte dehydrogenase (G-6-P- D) and influenza-typhoid leptospirosis] LA - Fre MH - Anemia, Hemolytic/*etiology MH - Case Report MH - Glucosephosphate Dehydrogenase Deficiency/*complications MH - Human MH - Influenza/*complications MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Typhoid/*complications PT - JOURNAL ARTICLE DA - 681025 DP - 1968 Mar-Apr TA - Bull Mem Soc Med Hop Paris PG - 545-50 CY - FRANCE IP - 6 VI - 119 JC - BP8 EM - 6812 PMID- 5674322 CU - 89 TT - Anemie par deficit en glucose-6-phosphate-deshydrogenase (G-6-P-D) et leptospirose grippt-typhosique. SO - Bull Mem Soc Med Hop Paris 1968 Mar-Apr;119(6):545-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 68240509 AU - Osechinskii IV AU - Mekler LB AU - Petrov RV AU - Mitiushin VM TI - [The use of iodinated antibodies in studying the cause of differences in the immunogenicity of Leptospira in relation to mice of different inbred strains (cytoimmunochemical analysis at the electron microscopy level)] LA - Rus MH - Animal MH - *Antibodies MH - IgG MH - IgM MH - Inbreeding MH - *Iodine MH - Leptospira canicola/*immunology MH - Leptospirosis/*immunology MH - *Mice MH - Microscopy, Electron MH - Rabbits PT - JOURNAL ARTICLE DA - 680709 DP - 1968 Mar IS - 0006-4041 TA - Biull Eksp Biol Med PG - 78-83 SB - M CY - USSR IP - 3 VI - 65 JC - A74 EM - 6808 PMID- 5650467 TT - Ispol'zovanie iodirovannykh antitel dlia izucheniia prichin razlichiia immunogennosti leptospir dlia myshei raznykh inbrednykh linii (tsitoimmunokhimicheskii analiz na urovne elektronnoi mikroskopii) SO - Biull Eksp Biol Med 1968 Mar;65(3):78-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68239345 AU - Faine S TI - Heated sheep or horse serum substitute for rabbit serum in culture media for Leptospira. LA - Eng MH - Animal MH - Blood MH - *Culture Media MH - Horses MH - Leptospira/*growth & development MH - Rabbits MH - Sheep PT - JOURNAL ARTICLE DA - 680709 DP - 1968 Mar IS - 0003-6919 TA - Appl Microbiol PG - 534 SB - M CY - UNITED STATES IP - 3 VI - 16 JC - 6K0 EM - 6808 PMID- 5649869 SO - Appl Microbiol 1968 Mar;16(3):534 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68192103 AU - Easton RE TI - Leptospirosis--social factors. Leptospirosis in prison inmates: social factors in communicable disease. LA - Eng MH - Adult MH - Carrier State MH - Human MH - Leptospirosis/diagnosis/*epidemiology MH - Male MH - Middle Age MH - *Prisons MH - Serodiagnosis MH - *Socioeconomic Factors PT - JOURNAL ARTICLE DA - 680523 DP - 1968 Mar IS - 0022-8699 TA - J Kans Med Soc PG - 147-50 CY - UNITED STATES IP - 3 VI - 69 JC - IRR EM - 6807 PMID- 5643905 CU - 88 SO - J Kans Med Soc 1968 Mar;69(3):147-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 68270345 AU - Ben-Efraim S AU - Torten M TI - Experimental induction of delayed ocular reactions resembling post- leptospirosis ophthalmia. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibodies/analysis MH - Dogs MH - Endophthalmitis/*etiology MH - Eye Diseases/immunology MH - Fluorescent Dyes MH - *Hypersensitivity, Delayed MH - Hypersensitivity, Immediate MH - Leptospira canicola MH - Leptospirosis/*complications/immunology MH - Skin Tests PT - JOURNAL ARTICLE DA - 680717 DP - 1968 Mar IS - 0022-1287 TA - J Gen Microbiol PG - Suppl:7-8 SB - M CY - ENGLAND IP - 3 VI - 50 JC - I87 EM - 6809 PMID- 5301228 CU - 89 SO - J Gen Microbiol 1968 Mar;50(3):Suppl:7-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 69092962 AU - Nicolesco M AU - Olinesco E TI - [Incidence of Leptospira antibodies in laboratory animals] LA - Fre MH - Animal MH - Animals, Laboratory/*immunology MH - *Antibodies MH - Guinea Pigs MH - Haplorhini MH - Leptospira/*immunology MH - Male MH - Mice MH - Rabbits MH - Rats MH - Sheep PT - JOURNAL ARTICLE DA - 690307 DP - 1968 Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 167-74 CY - ROMANIA IP - 1 VI - 27 JC - 8EM EM - 6904 PMID- 4974081 CU - 91 TT - Incidence des anticorps antileptospirotiques ches les animaux de laboratoire. SO - Arch Roum Pathol Exp Microbiol 1968 Mar;27(1):167-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 68401790 AU - Yanagihara Y AU - Mifuchi I AU - Azuma I AU - Yamamura Y TI - Studies on Pathogenic leptospirae. V. Growth of pathogenic leptospirae on lipid fractions obtained from acid-fast bacilli. LA - Eng MH - Animal MH - Centrifugation MH - Chloroform MH - Culture Media MH - Leptospira/*growth & development MH - Leptospira canicola/growth & development MH - Leptospira interrogans/growth & development MH - Lipids/analysis/*pharmacology MH - Mycobacterium/*analysis MH - Mycobacterium tuberculosis/analysis MH - Rabbits MH - Surface-Active Agents MH - Waxes/analysis/pharmacology PT - JOURNAL ARTICLE DA - 681025 DP - 1968 Mar IS - 0021-5139 TA - Jpn J Microbiol PG - 103-10 SB - M CY - JAPAN IP - 1 VI - 12 JC - KMF EM - 6812 PMID- 4970693 CU - 91 SO - Jpn J Microbiol 1968 Mar;12(1):103-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [5 medline neighbors] UI - 70066648 AU - Gilbert DN AU - Moore WL Jr AU - Hedberg CL AU - Sanford JP TI - Potential medical problems in personnel returning from Vietnam. LA - Eng MH - Arbovirus Infections/epidemiology MH - Chikungunya Virus MH - Communicable Diseases/epidemiology/therapy MH - Dengue/epidemiology MH - Diarrhea/etiology MH - Disease Reservoirs MH - Encephalitis, Japanese/epidemiology MH - Fever/etiology MH - Helminthiasis/epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Malaria/epidemiology MH - Male MH - Melioidosis/epidemiology MH - *Military Medicine MH - Plague/epidemiology MH - Scrub Typhus/epidemiology MH - Sprue, Tropical MH - Travel MH - *Tropical Medicine MH - United States MH - Vietnam PT - JOURNAL ARTICLE DA - 700205 DP - 1968 Mar IS - 0003-4819 TA - Ann Intern Med PG - 662-78 SB - A SB - M CY - UNITED STATES IP - 3 VI - 68 JC - 5A6 EM - 7003 PMID- 4311893 CU - 93 SO - Ann Intern Med 1968 Mar;68(3):662-78 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [138 medline neighbors] UI - 69001068 AU - Szyfres B AU - Sulzer CR AU - Galton MM TI - [A new leptospiral serotype of the Bataviae group isolated in Argentina] LA - Spa MH - Animal MH - Animal Diseases MH - Argentina MH - English Abstract MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 681120 DP - 1968 Mar IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 225-7 CY - UNITED STATES IP - 3 VI - 64 JC - AGG EM - 6901 PMID- 4234281 CU - 92 TT - Nuevo serotipo de Leptospira del grupo Bataviae aislado en la Argentina. SO - Bol Oficina Sanit Panam 1968 Mar;64(3):225-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 68242879 AU - Minette HP AU - Shaffer MF TI - Experimental leptospirosis in monkeys. LA - Eng MH - Animal MH - Antibody Formation MH - Blood/microbiology MH - Fluorescent Antibody Technique MH - Immune Sera MH - Leptospira/isolation & purification/*pathogenicity MH - Leptospira canicola/isolation & purification/pathogenicity MH - Leptospira interrogans/isolation & purification/pathogenicity MH - Leptospirosis/*immunology MH - *Monkey Diseases MH - Species Specificity MH - Staining MH - Time Factors MH - Tissue Culture MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 680710 DP - 1968 Mar IS - 0002-9637 TA - Am J Trop Med Hyg PG - 202-12 SB - A SB - M CY - UNITED STATES IP - 2 VI - 17 JC - 3ZQ EM - 6808 PMID- 4172221 CU - 95 SO - Am J Trop Med Hyg 1968 Mar;17(2):202-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 69005796 AU - Griem R AU - Oberdoerster F TI - [The significance of compulsory reporting in leptospiroses] LA - Ger MH - English Abstract MH - Germany, East MH - Human MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 681125 DP - 1968 Feb 29 IS - 0012-0219 TA - Dtsch Gesundheitsw PG - 424-5 CY - GERMANY, EAST IP - 9 VI - 23 JC - ECG EM - 6901 PMID- 5680699 CU - 88 TT - Die Bedeutung der Meldepflicht bei Leptospirosen. SO - Dtsch Gesundheitsw 1968 Feb 29;23(9):424-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 69001470 AU - Horsch F AU - Horsch R TI - [Occurrence of leptospirosis in dogs in the area of Berlin] LA - Ger MH - Animal MH - Berlin MH - Dog Diseases/*epidemiology MH - Dogs MH - English Abstract MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 681120 DP - 1968 Feb 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 142-5 CY - GERMANY, EAST IP - 4 VI - 23 JC - NGV EM - 6901 PMID- 5692753 CU - 88 TT - Zum Vorkommen der Leptospirose bei Hunden im Raum Berlin. SO - Monatsh Veterinarmed 1968 Feb 15;23(4):142-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70128456 AU - Medina F AU - Rumolo R AU - Rovescalli A TI - [On a case of leptospirosis due to L. poi] LA - Ita MH - Adult MH - Human MH - Leptospira/pathogenicity MH - Leptospirosis/*pathology MH - Male PT - JOURNAL ARTICLE DA - 700415 DP - 1968 Feb IS - 0017-0321 TA - G Mal Infett Parassit PG - 172-5 CY - ITALY IP - 2 VI - 20 JC - FD7 EM - 7006 PMID- 5741085 TT - Su di un caso di leptospirosi da L. poi. SO - G Mal Infett Parassit 1968 Feb;20(2):172-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68239688 AU - Sawhney AN TI - Leptospirosis in goats in Madhya Pradesh: a serological survey. LA - Eng MH - Animal MH - Female MH - Goats/*immunology MH - India MH - Leptospirosis/epidemiology/immunology/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 680709 DP - 1968 Feb IS - 0019-6479 TA - Indian Vet J PG - 103-7 CY - INDIA IP - 2 VI - 45 JC - GM9 EM - 6808 PMID- 5650041 CU - 88 SO - Indian Vet J 1968 Feb;45(2):103-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 68158655 AU - Stalheim OH TI - Biological effects of leptospiral lipids. LA - Eng MH - Animal MH - Antibody Formation/drug effects MH - Body Weight MH - Complement MH - Complement Fixation Tests MH - Hamsters MH - Immune Sera MH - Immunization MH - Leptospira/*immunology/pathogenicity MH - Lipids/*pharmacology/toxicity MH - Macrophages/drug effects MH - Mice MH - Phagocytosis/drug effects MH - Rabbits MH - Skin/drug effects MH - Virulence PT - JOURNAL ARTICLE DA - 680503 DP - 1968 Feb IS - 0021-9193 TA - J Bacteriol PG - 465-8 SB - M CY - UNITED STATES IP - 2 VI - 95 JC - HH3 EM - 6806 PMID- 5640382 SO - J Bacteriol 1968 Feb;95(2):465-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68158632 AU - Faine S AU - Carter JN TI - Natural antibody in mammalian serum reacting with an antigen in some leptospires. LA - Eng MH - Animal MH - *Antibodies/analysis MH - Antibody Formation MH - Blood Bactericidal Activity MH - Complement/pharmacology MH - Guinea Pigs MH - *Immunity MH - Immunoelectrophoresis MH - Leptospira/*immunology/pathogenicity MH - Leptospira interrogans/pathogenicity MH - Macroglobulins/analysis MH - Mice MH - Muramidase/pharmacology MH - Rabbits MH - Rats MH - Sheep MH - Virulence PT - JOURNAL ARTICLE DA - 680503 DP - 1968 Feb IS - 0021-9193 TA - J Bacteriol PG - 280-5 SB - M CY - UNITED STATES IP - 2 VI - 95 JC - HH3 EM - 6806 PMID- 5640374 SO - J Bacteriol 1968 Feb;95(2):280-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68156589 AU - Hubbert WT AU - Humphrey GL TI - Epidemiology of leptospirosis in California: a cause of aseptic meningitis. LA - Eng MH - California MH - Female MH - Human MH - Leptospirosis/*complications/epidemiology MH - Male MH - Meningitis/*etiology PT - JOURNAL ARTICLE DA - 680501 DP - 1968 Feb IS - 0008-1264 TA - Calif Med PG - 113-7 CY - UNITED STATES IP - 2 VI - 108 JC - CFU EM - 6806 PMID- 5639940 CU - 88 SO - Calif Med 1968 Feb;108(2):113-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 68163860 AU - Fear FA AU - Pinkerton ME AU - Cline JA AU - Kriewaldt F AU - Kalter SS TI - A leptospirosis outbreak in a baboon (Papio sp.) colony. LA - Eng MH - Animal MH - Animals, Newborn MH - Female MH - Hemagglutination Tests MH - Leptospira/isolation & purification MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*veterinary MH - *Monkey Diseases MH - Pregnancy MH - Seasons PT - JOURNAL ARTICLE DA - 680509 DP - 1968 Feb IS - 0094-5331 TA - Lab Anim Care PG - 22-8 SB - M CY - UNITED STATES IP - 1 VI - 18 JC - BDU EM - 6806 PMID- 4230579 CU - 92 SO - Lab Anim Care 1968 Feb;18(1):22-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 68330139 AU - Knorre G von TI - [Leptospirosis cases in 1966] LA - Ger MH - Adolescence MH - Aged MH - Female MH - Germany, West MH - Human MH - Leptospirosis/*diagnosis MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 680909 DP - 1968 Jan 27 IS - 0025-8512 TA - Med Welt PG - 274-6 CY - GERMANY, WEST VI - 4 JC - MIM EM - 6810 PMID- 5663161 TT - Leptospirosebeobachtungen 1966. SO - Med Welt 1968 Jan 27;4:274-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68134497 AU - Joyce-Clarke N AU - Michaels MJ TI - Leptospirosis in Cape Town. LA - Eng MH - Adolescence MH - Africa, Southern MH - Conjunctivitis/complications MH - Diagnosis, Differential MH - Hepatitis A/analysis MH - Human MH - Leptospira interrogans/isolation & purification MH - *Leptospirosis/microbiology MH - Male PT - JOURNAL ARTICLE DA - 680410 DP - 1968 Jan 20 IS - 0038-2469 TA - S Afr Med J PG - 57-8 SB - M CY - SOUTH AFRICA IP - 3 VI - 42 JC - U4R EM - 6805 PMID- 5638048 SO - S Afr Med J 1968 Jan 20;42(3):57-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68355497 AU - Minkenhof JE AU - Wolff JW AU - Bohlander HJ TI - [A case of leptospirosis caused by a serotype of the tarassovi (Hyos) serogroup] LA - Dut MH - Abattoirs MH - Human MH - Leptospira/immunology MH - Leptospirosis/*immunology MH - Male MH - Middle Age MH - Occupational Diseases PT - JOURNAL ARTICLE DA - 680916 DP - 1968 Jan 13 IS - 0028-2162 TA - Ned Tijdschr Geneeskd PG - 73-5 CY - NETHERLANDS IP - 2 VI - 112 JC - NUK EM - 6811 PMID- 5664971 TT - Een geval van leptospirose, veroorzaakt door een serotype van de tarassovi (hyos)-serogroep. SO - Ned Tijdschr Geneeskd 1968 Jan 13;112(2):73-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 68410477 AU - Yanagihara Y AU - Mifuchi I TI - [Pathogenic Leptospira. 7. Growth induced by various fatty acids and their derivatives] LA - Jpn MH - Culture Media MH - Fatty Acids/*pharmacology MH - Leptospira/*drug effects/growth & development PT - JOURNAL ARTICLE DA - 681106 DP - 1968 Jan 10 IS - 0019-1604 TA - Igaku To Seibutsugaku PG - 26-30 CY - JAPAN IP - 1 VI - 76 JC - LPA EM - 6812 PMID- 5692192 CU - 85 SO - Igaku To Seibutsugaku 1968 Jan 10;76(1):26-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69200179 AU - Silverie R AU - Monnier M AU - Lataste-Dorolle C TI - [Recent survey of leptospirosis on Madagascar. Contribution to the study of human, bovine and porcine leptospirosis in the southern region] LA - Fre MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - English Abstract MH - Human MH - Indian Ocean Islands MH - Leptospirosis/diagnosis/*epidemiology/veterinary MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 690724 DP - 1968 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 346-59 SB - M CY - FRANCE IP - 3 VI - 61 JC - C4G EM - 6909 PMID- 5756585 CU - 88 TT - Nouvelle enquete sur la leptospirose a Madagascar. Contribution a l'etude des leptospiroses humaines, bovines et porcines de la region sud. SO - Bull Soc Pathol Exot Filiales 1968;61(3):346-59 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 69087520 AU - Mailloux M TI - [Presence of antileptospira antibodies in rabbits] LA - Fre MH - Age Factors MH - Animal MH - Antibodies MH - Antigen-Antibody Reactions MH - Hemagglutination Tests MH - Leptospira/*immunology/*isolation & purification MH - Leptospira interrogans/immunology MH - Rabbits/*immunology PT - JOURNAL ARTICLE DA - 690304 DP - 1968 IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 149-54 SB - M CY - FRANCE IP - 2 VI - 61 JC - C4G EM - 6904 PMID- 5755451 CU - 86 TT - Presence d'anticorps antileptospira chez le lapin. SO - Bull Soc Pathol Exot Filiales 1968;61(2):149-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 70090535 AU - Dubakin NI TI - [A modification of the technic of microagglutination and lysis tests for leptospirosis in animals] LA - Rus MH - Animal MH - Hemagglutination Tests/*veterinary MH - Hemolysis MH - Leptospirosis/*veterinary MH - Methods MH - Serodiagnosis/*veterinary PT - JOURNAL ARTICLE DA - 700305 DP - 1968 Jan IS - 0042-4846 TA - Veterinariia PG - 103-4 CY - USSR IP - 1 VI - 45 JC - XCC EM - 7004 PMID- 5754159 CU - 90 TT - Modifikatsiia tekhniki postanovki reaktsii mikroaggliutinatsii i lizisa na leptospiroz zhivotnykh. SO - Veterinariia 1968 Jan;45(1):103-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 69237967 AU - Tagi-Zade TA TI - [The state and prospects of studying the leptospiroses in the Azerbaijan SSR] LA - Rus MH - Animal MH - Disease Reservoirs MH - Disease Vectors MH - Human MH - Leptospira/classification MH - *Leptospirosis/microbiology MH - Mammals MH - Occupational Diseases MH - Siberia MH - Water PT - JOURNAL ARTICLE DA - 690904 DP - 1968 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 47-51 SB - M CY - USSR IP - 10 VI - 45 JC - Y9O EM - 6910 PMID- 5753488 CU - 89 TT - Sostoianie i perspektivy izucheniia leptospirozov v azerbaidzhanskoi SSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1968;45(10):47-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 69237966 AU - Drankin DI AU - Godlevskaia MV TI - [Epidemiology of swamp fever. IV. Epidemiological characteristics of drinking water infections] LA - Rus MH - Animal MH - Animals, Domestic MH - Disease Reservoirs MH - Disease Vectors MH - Drinking MH - Human MH - Leptospira MH - *Leptospirosis/microbiology/prevention & control MH - Rodentia MH - Water MH - Water Pollution/prevention & control PT - JOURNAL ARTICLE DA - 690904 DP - 1968 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 42-7 SB - M CY - USSR IP - 10 VI - 45 JC - Y9O EM - 6910 PMID- 5753487 CU - 89 TT - K epidemiologii vodnoi likhoradki. IV. Epidemiologicheskaia kharakteristika zabolevanii pri vodno-pit'evykh zarazheniiakh. SO - Zh Mikrobiol Epidemiol Immunobiol 1968;45(10):42-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 69203283 AU - Chorvath B TI - Studies on leptospiral lipase. I. Characterization of lipases from pathogenic and saprophytic strains. LA - Eng MH - Bacterial Proteins/analysis MH - Comparative Study MH - Hydrogen-Ion Concentration MH - Kinetics MH - Leptospira/*enzymology/pathogenicity MH - Leptospira interrogans/*metabolism MH - Lipase/*metabolism MH - Temperature PT - JOURNAL ARTICLE DA - 690730 DP - 1968 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 349-55 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 12 JC - IEV EM - 6909 PMID- 5753320 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1968;12(3):349-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 69203282 AU - Kiktenko VS TI - On the specific mechanism of the transmission of leptospiral infection. LA - Eng MH - Animal MH - Coitus MH - *Communicable Diseases MH - Disease Reservoirs MH - Disease Vectors MH - Human MH - Kidney/microbiology MH - *Leptospira MH - *Leptospirosis MH - Urine/microbiology MH - Water Microbiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 690730 DP - 1968 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 341-8 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 12 JC - IEV EM - 6909 PMID- 5753319 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1968;12(3):341-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69135708 AU - Cernukha YG AU - Isayeva RA TI - Serological classification of Soviet strains of Leptospira belonging to the group hebdomadis. LA - Eng MH - Agglutination Tests MH - Antigens MH - Immune Sera MH - Leptospira/*classification MH - Serotyping MH - USSR PT - JOURNAL ARTICLE DA - 690501 DP - 1968 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 473-81 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 12 JC - IEV EM - 6906 PMID- 5752131 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1968;12(4):473-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [97 medline neighbors] UI - 70254662 AU - Mailloux M TI - [The effect of diverse temperature on Leptospirae] LA - Fre MH - English Abstract MH - *Heat MH - Leptospira/*growth & development/pathogenicity MH - Leptospira canicola/growth & development MH - Leptospira interrogans/growth & development MH - Serotyping PT - JOURNAL ARTICLE DA - 700922 DP - 1968 TA - Zentralbl Bakteriol [Orig] PG - 377-81 SB - M CY - GERMANY, WEST IP - 3 VI - 207 JC - Y4Y EM - 7011 PMID- 5745679 CU - 89 TT - Action de diverses temperatures sur les germes du genre leptospira. SO - Zentralbl Bakteriol [Orig] 1968;207(3):377-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 70254661 AU - Burger G TI - [The effect of ethyl urethane and cyclophosphamide on reproduction and oxygen consumption of Leptospira semaranga (Veldrat S 173)] LA - Ger MH - Chemistry MH - Culture Media MH - Cyclophosphamide/*pharmacology MH - Depression, Chemical MH - English Abstract MH - Leptospira/*drug effects/growth & development/metabolism MH - Oxygen Consumption/*drug effects MH - Reproduction/*drug effects MH - Urethane/*pharmacology PT - JOURNAL ARTICLE DA - 700922 DP - 1968 TA - Zentralbl Bakteriol [Orig] PG - 365-77 SB - M CY - GERMANY, WEST IP - 3 VI - 207 JC - Y4Y EM - 7011 PMID- 5745678 CU - 89 TT - Einfluss von Aethylurethan und Cyclophosphamid auf Vermerhrung und Atmung von Leptospira semaranga (Veldrat S 173) SO - Zentralbl Bakteriol [Orig] 1968;207(3):365-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 69298506 AU - Aktan M TI - [Leptospirosis and studies made in our country on human leptospirosis] LA - Tur MH - Agglutination Tests MH - Antibiotics/therapeutic use MH - English Abstract MH - Human MH - Leptospira/isolation & purification MH - *Leptospirosis/complications/drug therapy/epidemiology/prevention & control MH - Prognosis MH - Turkey PT - JOURNAL ARTICLE DA - 691105 DP - 1968 IS - 0049-4844 TA - Turk Hij Tecr Biyol Derg PG - 30-56 CY - TURKEY IP - 1 VI - 28 JC - WKI EM - 6912 PMID- 5735308 CU - 88 TT - Leptospirozisler ve yurdumuzda insan leptospirozizleri uzerinde yapilan calismalar. SO - Turk Hij Tecr Biyol Derg 1968;28(1):30-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 69159715 AU - Kemenes F TI - Studies on adaptability to albino mice of leptospires isolated in Hungary. LA - Eng MH - Animal MH - Guinea Pigs MH - Kidney/*microbiology MH - Leptospira/*isolation & purification MH - Mice PT - JOURNAL ARTICLE DA - 690525 DP - 1968 IS - 0001-7205 TA - Acta Vet Acad Sci Hung PG - 379-88 CY - HUNGARY IP - 4 VI - 18 JC - 27P EM - 6907 PMID- 5719592 SO - Acta Vet Acad Sci Hung 1968;18(4):379-88 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69014551 AU - Gascard E AU - Daniel F AU - Cherif AA AU - Levy P TI - [Meningeal leptospirosis due to Leptospira canicola] LA - Fre MH - Adult MH - Animal MH - Dogs MH - Female MH - Human MH - *Leptospira canicola MH - Leptospirosis/*complications MH - Male MH - Meningitis/*etiology PT - JOURNAL ARTICLE DA - 681208 DP - 1968 IS - 0025-4053 TA - Mars Med PG - 617-21 CY - FRANCE IP - 7 VI - 105 JC - LJI EM - 6901 PMID- 5693437 CU - 85 TT - Leptospirose meningee a Leptospira canicola. SO - Mars Med 1968;105(7):617-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68367673 AU - Sirca B AU - Merca V AU - Blassy E AU - Riznicu G TI - [Some epidemiological and laboratory aspects of leptospirosis and brucellosis in the Crisana region between 1962 and 1966] LA - Rum MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Animal MH - Brucellosis/*epidemiology MH - Child MH - Child, Preschool MH - Human MH - Infant MH - Leptospirosis/*epidemiology MH - Middle Age MH - Occupations MH - Romania MH - Seasons MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 681006 DP - 1968 Jan-Feb IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 59-65 CY - ROMANIA IP - 1 VI - 13 JC - MXQ EM - 6811 PMID- 5691353 CU - 88 TT - Unele aspecte epidemiologice si de laborator privind leptospiroza si bruceloza in Regiunea Crisana intre anii 1962 si 1966. SO - Microbiol Parazitol Epidemiol (Bucur) 1968 Jan-Feb;13(1):59-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68245524 AU - Kharole MU AU - Rao UR TI - Leptospirosis in goats in India. LA - Eng MH - Animal MH - *Goats MH - India MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 680710 DP - 1968 Jan IS - 0019-6479 TA - Indian Vet J PG - 14-8 CY - INDIA IP - 1 VI - 45 JC - GM9 EM - 6808 PMID- 5689965 CU - 85 SO - Indian Vet J 1968 Jan;45(1):14-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68191217 AU - Lucke VM TI - Renal disease in the domestic cat. LA - Eng MH - Animal MH - Blood Urea Nitrogen MH - Cat Diseases/*pathology MH - Cats MH - Kidney/microbiology/*pathology MH - Kidney Diseases/pathology/*veterinary MH - Leptospira/isolation & purification MH - Organ Weight MH - Parathyroid Glands/pathology PT - JOURNAL ARTICLE DA - 680522 DP - 1968 Jan TA - J Pathol Bacteriol PG - 67-91 CY - ENGLAND IP - 1 VI - 95 JC - JLJ EM - 6807 PMID- 5689371 CU - 89 SO - J Pathol Bacteriol 1968 Jan;95(1):67-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 68191214 AU - Anderson LJ TI - Arterial disease in canine interstitial nephritis. LA - Eng MH - Animal MH - Arteries/*pathology MH - Dog Diseases/*pathology MH - Dogs MH - Female MH - Leptospira canicola MH - Leptospirosis/pathology/*veterinary MH - Male MH - Nephritis, Interstitial/pathology/*veterinary MH - Vascular Diseases/pathology/veterinary PT - JOURNAL ARTICLE DA - 680522 DP - 1968 Jan TA - J Pathol Bacteriol PG - 47-53 CY - ENGLAND IP - 1 VI - 95 JC - JLJ EM - 6807 PMID- 5689369 CU - 89 SO - J Pathol Bacteriol 1968 Jan;95(1):47-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68155010 AU - Meers PD AU - Ringrose MA TI - A simplified sensitized erythrocyte lysis test for leptospirosis. LA - Eng MH - Animal MH - Antibodies/analysis MH - Antigens MH - Complement Fixation Tests MH - *Erythrocytes MH - Hemolysis MH - Human MH - Leptospira MH - Leptospirosis/*diagnosis/immunology MH - Methods MH - Serodiagnosis MH - Sheep PT - JOURNAL ARTICLE DA - 680428 DP - 1968 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 105-8 SB - M CY - ENGLAND IP - 1 VI - 62 JC - WBU EM - 6806 PMID- 5689078 CU - 90 SO - Trans R Soc Trop Med Hyg 1968;62(1):105-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 68408021 AU - Obodowska-Zysk W TI - [2 cases of concurrent typhoid fever and leptospirosis] LA - Pol MH - Adolescence MH - Case Report MH - Female MH - Human MH - Leptospirosis/*complications MH - Middle Age MH - Typhoid/*complications PT - JOURNAL ARTICLE DA - 681101 DP - 1968 IS - 0033-2240 TA - Przegl Lek PG - 377-8 CY - POLAND IP - 3 VI - 24 JC - Q96 EM - 6812 PMID- 5676277 TT - Dwa przypadki jednoczesnego zachorowania na dur brzuszny i leptospiroze. SO - Przegl Lek 1968;24(3):377-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 68391125 AU - Bakoss P AU - Chorvath B TI - [Effect of antibiotic treatment on antibody formation in leptospiral diseases. VI. Effect of streptomycin, oxytetracycline and penicillin on antibody formation in experimentally infected guinea pigs] LA - Slo MH - Animal MH - Antibiotics/*therapeutic use MH - *Antibody Formation MH - Guinea Pigs MH - Leptospirosis/*immunology MH - Oxytetracycline/therapeutic use MH - Penicillins/therapeutic use MH - Streptomycin/therapeutic use PT - JOURNAL ARTICLE DA - 681011 DP - 1968 IS - 0006-9248 TA - Bratisl Lek Listy PG - 283-93 CY - CZECHOSLOVAKIA IP - 3 VI - 49 JC - B5N EM - 6812 PMID- 5670568 TT - Vplyv liecby antibiotikami na tvorbu protilatok pri leptospirovych ochoreniach. VI. Vplyv streptomycinu, oxytetracyklinu a penicilinu na tvorbu protilatok u experimentalne infikovanych morciat. SO - Bratisl Lek Listy 1968;49(3):283-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68367389 AU - Bakoss P AU - Chorvath B TI - [Effect of antibiotic treatment on antibody formation in leptospiral diseases. V. Effect of streptomycin on antibody formation in experimentally infected rabbits] LA - Slo MH - Animal MH - Antibody Formation/*drug effects MH - Antigens MH - Leptospirosis/*immunology MH - Rabbits MH - Streptomycin/*therapeutic use PT - JOURNAL ARTICLE DA - 681006 DP - 1968 IS - 0006-9248 TA - Bratisl Lek Listy PG - 160-6 CY - CZECHOSLOVAKIA IP - 2 VI - 49 JC - B5N EM - 6811 PMID- 5669489 TT - Vplyv liecby antibiotikami na tvorbu protilatok pri leptospirovych ochoreniach. V. Vplyv streptomycinu na tvorbu protilatok u experimentalne infikovanych kralikov. SO - Bratisl Lek Listy 1968;49(2):160-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68367377 AU - Hruzik J AU - Bakoss P AU - Osvald F TI - [Experiences with treatment of leptospiroses with antibiotics] LA - Slo MH - Antibiotics/*therapeutic use MH - Human MH - Leptospira canicola/immunology MH - Leptospirosis/*drug therapy MH - Penicillins/therapeutic use MH - Tetracycline/therapeutic use MH - Weil's Disease/drug therapy PT - JOURNAL ARTICLE DA - 681006 DP - 1968 Jan IS - 0006-9248 TA - Bratisl Lek Listy PG - 50-7 CY - CZECHOSLOVAKIA IP - 1 VI - 49 JC - B5N EM - 6811 PMID- 5669478 TT - Skusenosti s terapiou leptospiroz antibiotikami. SO - Bratisl Lek Listy 1968 Jan;49(1):50-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68366815 AU - Nasilowska M TI - [Frequency of occurrence of agglutinins for the Leptospira lublin and Leptospira semaranga strains in the sera of patients suspected of leptospirosis] LA - Pol MH - Agglutination Tests MH - Human MH - Leptospira/*isolation & purification MH - Leptospira canicola/*isolation & purification MH - Leptospira interrogans/*isolation & purification MH - Leptospirosis/*microbiology PT - JOURNAL ARTICLE DA - 681006 DP - 1968 IS - 0033-2100 TA - Przegl Epidemiol PG - 51-6 CY - POLAND IP - 1 VI - 22 JC - Q8T EM - 6811 PMID- 5669175 TT - Czestosc wystepowania aglutynin dla szczepow Leptospira lublin i Leptospira semaranga w surowicach chorych podejrzanych o leptospiroze. SO - Przegl Epidemiol 1968;22(1):51-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68366814 AU - Anusz Z TI - [Epidemiologic situation of leptospiroses in the world, with special reference to Poland in 1960-1966] LA - Pol MH - Africa MH - Asia MH - Europe MH - Human MH - Leptospirosis/*epidemiology MH - North America MH - Poland MH - South America PT - JOURNAL ARTICLE DA - 681006 DP - 1968 IS - 0033-2100 TA - Przegl Epidemiol PG - 45-50 CY - POLAND IP - 1 VI - 22 JC - Q8T EM - 6811 PMID- 5669174 CU - 88 TT - Sytuacja epidemiologiczna leptospiroz w swiecie ze szczegolnym uwzglednieniem Polski w latch 1960-1966. SO - Przegl Epidemiol 1968;22(1):45-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 68357839 AU - Varju L TI - [Leptospirosis in ground squirrels (Citellus citellus) (brief report)] LA - Ger MH - Animal MH - *Leptospirosis MH - Rats MH - Rodent Diseases MH - *Sciuridae PT - JOURNAL ARTICLE DA - 680925 DP - 1968 IS - 0001-7205 TA - Acta Vet Acad Sci Hung PG - 111-3 CY - HUNGARY IP - 1 VI - 18 JC - 27P EM - 6811 PMID- 5665841 TT - Erkrankung an Leptospirose von Zieselmausen (Citellus citellus) (Kurze Mitteilung) SO - Acta Vet Acad Sci Hung 1968;18(1):111-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68313014 AU - Manyko VM AU - Sidorovich IG AU - Zhabina MI AU - Petrov RV TI - Loss of secondary reaction by antibody-forming cells cultivated in vivo. LA - Eng MH - Animal MH - Antibodies/analysis MH - *Antibody Formation MH - Leptospira MH - Mice MH - Phagocytosis MH - Spleen MH - Tissue Culture PT - JOURNAL ARTICLE DA - 680816 DP - 1968 IS - 0015-5500 TA - Folia Biol (Praha) PG - 239-42 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 14 JC - EYH EM - 6810 PMID- 5658484 SO - Folia Biol (Praha) 1968;14(3):239-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 68125854 AU - Braun JL AU - McCulloch WF TI - Use of 8-azaguanine to differentiate leptospires isolated from Iowa surface waters. LA - Eng MH - Azaguanine/*pharmacology MH - Leptospira/classification/drug effects/*isolation & purification/pathogenicity MH - Leptospira interrogans/isolation & purification MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 680404 DP - 1968 Jan IS - 0003-6919 TA - Appl Microbiol PG - 174-5 SB - M CY - UNITED STATES IP - 1 VI - 16 JC - 6K0 EM - 6805 PMID- 5636463 SO - Appl Microbiol 1968 Jan;16(1):174-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [176 medline neighbors] UI - 68124125 AU - Ellinghausen HC Jr TI - Stimulation of leptospiral growth by glucose. LA - Eng MH - Carbon Isotopes MH - Glucosamine/pharmacology MH - Glucose/*pharmacology MH - Leptospira/drug effects/*growth & development MH - Oxygen Consumption/drug effects PT - JOURNAL ARTICLE DA - 680330 DP - 1968 Jan IS - 0002-9645 TA - Am J Vet Res PG - 191-9 SB - M CY - UNITED STATES IP - 1 VI - 29 JC - 40C EM - 6805 PMID- 5636036 SO - Am J Vet Res 1968 Jan;29(1):191-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69232581 AU - Addamiano L AU - Babudieri B TI - Water strains of Leptospira in the serodiagnosis of human and animal leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Complement Fixation Tests MH - Human MH - *Leptospira MH - Leptospirosis/*immunology/*veterinary MH - Water PT - JOURNAL ARTICLE DA - 690827 DP - 1968 IS - 0042-9686 TA - Bull World Health Organ PG - 925-34 CY - SWITZERLAND IP - 6 VI - 39 JC - C80 EM - 6910 PMID- 5306103 CU - 89 SO - Bull World Health Organ 1968;39(6):925-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [174 medline neighbors] UI - 69086486 AU - Hoeden J van der TI - Agglutination of leptospirae in sera of fresh water turtles. LA - Eng MH - Age Factors MH - *Agglutination MH - Animal MH - Antigens/*analysis MH - Leptospira/*immunology MH - Serum Globulins/*analysis MH - Species Specificity MH - *Turtles PT - JOURNAL ARTICLE DA - 690228 DP - 1968 IS - 0003-6072 TA - Antonie Van Leeuwenhoek PG - 458-64 SB - M CY - NETHERLANDS IP - 4 VI - 34 JC - 6JE EM - 6904 PMID- 5304019 CU - 89 SO - Antonie Van Leeuwenhoek 1968;34(4):458-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69266012 AU - Anthony HD AU - Capel SW AU - Peabody WC TI - Survey of leptospirosis agglutination titers in serums collected from deer in Kansas. LA - Eng MH - Agglutination Tests MH - Animal MH - *Deer MH - Kansas MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 691005 DP - 1968 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 192-6 CY - UNITED STATES VI - 72 JC - PY5 EM - 6911 PMID- 5257461 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1968;72:192-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69266011 AU - Stalheim OH TI - Avirulent leptospira pomona vaccine: stability of the noninfectious character in vitro and in vivo. LA - Eng MH - Agglutination Tests MH - Animal MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*prevention & control MH - Leptospira/*growth & development/pathogenicity MH - Leptospirosis/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 691005 DP - 1968 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 182-91 CY - UNITED STATES VI - 72 JC - PY5 EM - 6911 PMID- 5257460 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1968;72:182-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 68155026 AU - Todorovic R AU - Ristic M AU - Ferris D TI - A tube latex agglutination test for the diagnosis of malaria. LA - Eng MH - Animal MH - Antibodies/analysis MH - Antigens MH - Babesiosis/immunology MH - Blood/physiopathology MH - Cattle MH - Chickens MH - Erythrocytes MH - Haplorhini MH - Human MH - Immunodiffusion MH - *Latex Fixation Tests MH - Leptospira/immunology MH - Malaria/*diagnosis MH - Malaria, Avian/diagnosis MH - Male MH - Plasmodium/immunology MH - Plasmodium falciparum/immunology MH - Plasmodium malariae/immunology MH - Plasmodium vivax/immunology MH - Rats MH - Serodiagnosis MH - Treponema pallidum/immunology PT - JOURNAL ARTICLE DA - 680428 DP - 1968 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 58-68 SB - M CY - ENGLAND IP - 1 VI - 62 JC - WBU EM - 6806 PMID- 4966430 CU - 91 SO - Trans R Soc Trop Med Hyg 1968;62(1):58-68 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 68155025 AU - Todorovic R AU - Ristic M AU - Ferris D TI - Soluble antigens of Plasmodium gallinaceum. LA - Eng MH - Animal MH - Antibodies/analysis MH - Antigens/*analysis MH - Babesiosis/immunology MH - Cattle MH - Chickens MH - Chromatography MH - Erythrocytes MH - Haplorhini MH - Human MH - Immune Sera MH - Leptospirosis/immunology MH - Malaria, Avian/*immunology MH - Mice MH - Plasmodium/*immunology MH - Plasmodium falciparum/immunology MH - Plasmodium malariae/immunology MH - Plasmodium vivax/immunology MH - Precipitin Tests MH - Rats MH - Species Specificity MH - Treponema pallidum/immunology PT - JOURNAL ARTICLE DA - 680428 DP - 1968 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 51-7 SB - M CY - ENGLAND IP - 1 VI - 62 JC - WBU EM - 6806 PMID- 4966429 CU - 91 SO - Trans R Soc Trop Med Hyg 1968;62(1):51-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 69288378 AU - Fagiolo U AU - Babudieri B TI - [Direct immunofluorescence reaction in the differentiation of leptospires] LA - Ita MH - Agglutination Tests MH - Antigens MH - English Abstract MH - Fluorescent Antibody Technique MH - Immune Sera MH - Leptospira/*classification MH - Serotyping PT - JOURNAL ARTICLE DA - 691027 DP - 1968 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 344-50 SB - M CY - ITALY IP - 3 VI - 4 JC - 5BP EM - 6912 PMID- 4897521 CU - 90 TT - La reazione di immunofluorescenza diretta nella sistematica delle leptospire. SO - Ann Ist Super Sanita 1968;4(3):344-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69288372 AU - Magliocchetti-Lombi P AU - Babudieri B TI - [Research on associated leptospira cultures] LA - Ita MH - Bacteriological Techniques MH - Culture Media MH - English Abstract MH - Leptospira/classification/*growth & development/immunology MH - Serotyping PT - JOURNAL ARTICLE DA - 691027 DP - 1968 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 291-304 SB - M CY - ITALY IP - 3 VI - 4 JC - 5BP EM - 6912 PMID- 4897520 CU - 90 TT - Ricerche su colture associate di leptospire. SO - Ann Ist Super Sanita 1968;4(3):291-304 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69232583 AU - Babudieri B TI - A new technique for the purification of newly isolated Leptospira strains. LA - Eng MH - *Bacteriological Techniques MH - Leptospira/*isolation & purification PT - JOURNAL ARTICLE DA - 690827 DP - 1968 IS - 0042-9686 TA - Bull World Health Organ PG - 939-40 CY - SWITZERLAND IP - 6 VI - 39 JC - C80 EM - 6910 PMID- 4893494 CU - 90 SO - Bull World Health Organ 1968;39(6):939-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69210356 AU - Turner LH TI - Leptospirosis. II. Serology. LA - Eng MH - Agglutination Tests MH - Antigen-Antibody Reactions MH - Antigens MH - Carrier State MH - Complement Fixation Tests MH - Fluorescent Antibody Technique MH - Hemagglutination Tests MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis MH - Species Specificity MH - Time Factors PT - JOURNAL ARTICLE PT - REVIEW DA - 690803 DP - 1968 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 880-99 SB - M CY - ENGLAND IP - 6 VI - 62 JC - WBU EM - 6909 RF - 69 PMID- 4891865 CU - 90 SO - Trans R Soc Trop Med Hyg 1968;62(6):880-99 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 69039230 AU - Parnas J AU - Poplawski S AU - Cybulska MT AU - Ksiazek A TI - The sugars, aminosugars and amino acid building blocks (chemotypes) and the serotypes of Leptospirae. LA - Eng MH - Amino Acids/*analysis MH - Amino Sugars/*analysis MH - Bacteriological Techniques MH - Chromatography MH - Hexoses/analysis MH - Leptospira/*classification MH - Pentoses/analysis MH - Serotyping PT - JOURNAL ARTICLE DA - 690110 DP - 1968 IS - 0001-4087 TA - Bull Acad Pol Sci [Biol] PG - 347-51 CY - POLAND IP - 6 VI - 16 JC - B8W EM - 6902 PMID- 4880804 CU - 90 SO - Bull Acad Pol Sci [Biol] 1968;16(6):347-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [128 medline neighbors] UI - 69032953 AU - Babudieri B TI - [Use of immunofluorescent antibody technic in the diagnosis of bacterial and viral diseases] LA - Ita MH - Brucellosis/immunology MH - Communicable Diseases/*immunology MH - *Fluorescent Antibody Technique MH - Gonorrhea/immunology MH - Human MH - Leptospirosis/immunology MH - Mycobacterium Infections/immunology MH - Mycoses/immunology MH - Pasteurella Infections/immunology MH - Streptococcal Infections/immunology MH - Virus Diseases/*immunology MH - Whooping Cough/immunology PT - JOURNAL ARTICLE PT - REVIEW DA - 690104 DP - 1968 Jan IS - 0017-0321 TA - G Mal Infett Parassit PG - 35-49 CY - ITALY IP - 1 VI - 20 JC - FD7 EM - 6902 RF - 143 PMID- 4880278 CU - 90 TT - Impiego delle reazioni di immunofluorescenza nella diagnosi delle malattie batteriche e virali. SO - G Mal Infett Parassit 1968 Jan;20(1):35-49 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 69203284 AU - Varfolomeeva AA AU - Kanareykina SK AU - Kozlova EP TI - The classification of leptospiral strains from Kazakhstan. LA - Eng MH - Animal MH - Biological Assay MH - Copper/pharmacology MH - Drug Resistance, Microbial MH - Human MH - Kazakhstan MH - Leptospira/*classification/enzymology/growth & development/immunology/isolation & purification/pathogenicity MH - Leptospira interrogans/*classification MH - Rabbits PT - JOURNAL ARTICLE DA - 690730 DP - 1968 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 356-64 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 12 JC - IEV EM - 6909 PMID- 4239373 CU - 92 SO - J Hyg Epidemiol Microbiol Immunol 1968;12(3):356-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [122 medline neighbors] UI - 69254421 AU - Tali-Zade TA AU - Klepko GD TI - [Petroleum growth substance as a stimulator of leptospira growth] LA - Rus MH - Growth Substances/*pharmacology MH - Leptospira/drug effects/*growth & development MH - Petroleum/*pharmacology MH - Stimulation, Chemical PT - JOURNAL ARTICLE DA - 690920 DP - 1968 IS - 0023-6748 TA - Lab Delo PG - 491-3 CY - USSR VI - 8 JC - KYU EM - 6911 PMID- 4184059 CU - 95 TT - Neftianoe rostovoe veshchestvo kak stimuliator rosta leptospir. SO - Lab Delo 1968;8:491-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69254420 AU - Krupnikova AM AU - Trop IE AU - Gansburg NP TI - [Reaction of indirect hemagglutination for laboratory diagnosis of leptospiroses] LA - Rus MH - *Diagnosis, Laboratory MH - *Hemagglutination Tests MH - Human MH - Leptospirosis/*diagnosis/immunology PT - JOURNAL ARTICLE DA - 690920 DP - 1968 IS - 0023-6748 TA - Lab Delo PG - 489-91 CY - USSR VI - 8 JC - KYU EM - 6911 PMID- 4184058 CU - 95 TT - Reaktsiia nepriamoi gemaggliutinatsii dlia laboratornoi diagnostiki leptospirozov. SO - Lab Delo 1968;8:489-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [62 medline neighbors] UI - 69254419 AU - Kiktenko VS AU - Levina LF TI - [On the effect of the salts of heavy metals of pathogenic and saprophytic leptosira] LA - Rus MH - Drug Resistance, Microbial MH - Leptospira/*drug effects/growth & development MH - Mercury/*pharmacology MH - Nitrates/*pharmacology MH - Silver Nitrate/*pharmacology PT - JOURNAL ARTICLE DA - 690920 DP - 1968 IS - 0023-6748 TA - Lab Delo PG - 487-9 CY - USSR VI - 8 JC - KYU EM - 6911 PMID- 4184057 CU - 95 TT - O vliianii solei tiazhelykh metallov na patogennye i saprofitnye leptospiry. SO - Lab Delo 1968;8:487-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 68313930 AU - Tutov IK TI - [On a method of luminescent microphogography of Leptospira] LA - Rus MH - *Leptospira MH - *Microscopy, Fluorescence MH - *Photography PT - JOURNAL ARTICLE DA - 680816 DP - 1968 IS - 0023-6748 TA - Lab Delo PG - 226-7 CY - USSR VI - 4 JC - KYU EM - 6810 PMID- 4173199 CU - 95 TT - K metodike liuminestsentnoi mikrofotografii leptospir. SO - Lab Delo 1968;4:226-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69238947 AU - Kosmachevskii VV AU - Chernousova AV TI - [Classification of the clinical forms of leptospirosis] LA - Rus MH - Human MH - Leptospirosis/*classification/diagnosis PT - JOURNAL ARTICLE DA - 690904 DP - 1967 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 65-7 SB - M CY - USSR IP - 12 VI - 44 JC - Y9O EM - 6910 PMID- 5616854 CU - 89 TT - Klassifikatsiia klinicheskikh form leptospirozov. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Dec;44(12):65-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 69238924 AU - Lavrent'ev NI TI - [Various features of pomona type leptospirosis in a kind of field mouse under experimental conditions] LA - Rus MH - Animal MH - Antibodies/analysis MH - Leptospirosis/immunology/*microbiology/urine MH - Mice PT - JOURNAL ARTICLE DA - 690904 DP - 1967 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 131 SB - M CY - USSR IP - 12 VI - 44 JC - Y9O EM - 6910 PMID- 5616840 CU - 89 TT - Nekotorye osobennosti leptospiroznoi infektsii tipa romona u polevok- ekonomok v eksperimente. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Dec;44(12):131 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69102019 AU - Nicolesco M TI - [Diagnosis by complement fixation tests with antigen mixtures in the detection of animal leptospirosis] LA - Fre MH - Animal MH - Cattle MH - Complement Fixation Tests MH - Dogs MH - Horses MH - Human MH - Leptospirosis/*diagnosis/veterinary MH - Swine PT - JOURNAL ARTICLE DA - 690318 DP - 1967 Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 761-7 CY - ROMANIA IP - 4 VI - 26 JC - 8EM EM - 6905 PMID- 5605452 TT - Diagnostic par la reaction de fixatin du complement avdc des melan ges d'antigenes pour le depistage des leptospiroses animales. SO - Arch Roum Pathol Exp Microbiol 1967 Dec;26(4):761-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68359819 AU - Thirunavukkarasu K AU - De Silva VN AU - Amarasinghe G TI - Leptospirosis in Ceylonese children. LA - Eng MH - Age Factors MH - Body Weight MH - Child MH - Child, Preschool MH - Female MH - Human MH - Infant MH - Leptospirosis/*epidemiology MH - Male MH - Sex Factors MH - Sri Lanka PT - JOURNAL ARTICLE DA - 680928 DP - 1967 Dec IS - 0009-0875 TA - Ceylon Med J PG - 202-5 CY - SRI LANKA IP - 4 VI - 12 JC - CY9 EM - 6811 PMID- 5599940 CU - 88 SO - Ceylon Med J 1967 Dec;12(4):202-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 68408624 AU - Okuda K AU - Yasumoto M AU - Arimatsu Y TI - [Weil's disease] LA - Jpn MH - Adult MH - Animal MH - Antibiotics/therapeutic use MH - Blood Chemical Analysis MH - Female MH - Guinea Pigs MH - Human MH - *Leptospirosis MH - Liver/pathology MH - *Weil's Disease PT - JOURNAL ARTICLE DA - 681101 DP - 1967 Dec IS - 0547-1729 TA - Naika PG - 1220-5 CY - JAPAN IP - 7 VI - 20 JC - NQO EM - 6812 PMID- 5599121 SO - Naika 1967 Dec;20(7):1220-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 68359825 AU - Nagaratnam N AU - Weerasinghe WM AU - Fernandopulle M TI - Leptosiprosis (anicteric) as a cause of long and short term pyrexia in the Kegalla district (Ceylon). LA - Eng MH - Adolescence MH - Adult MH - Case Report MH - Child MH - Female MH - Fever/*etiology MH - Human MH - Leptospirosis/*complications MH - Male MH - Sri Lanka MH - Tropical Medicine PT - JOURNAL ARTICLE DA - 680928 DP - 1967 Dec IS - 0009-0875 TA - Ceylon Med J PG - 225-8 CY - SRI LANKA IP - 4 VI - 12 JC - CY9 EM - 6811 PMID- 5594774 SO - Ceylon Med J 1967 Dec;12(4):225-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [154 medline neighbors] UI - 68274178 AU - Sawhney AN AU - Saxena SP TI - Leptospiral infections in domestic animals and man in the state of Madhya Pradesh. Incidence in sheep, dogs and pigs. (A serological study). LA - Eng MH - Animal MH - *Animals, Domestic MH - Dogs MH - Female MH - Human MH - India MH - Leptospirosis/*veterinary MH - Male MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 680729 DP - 1967 Dec IS - 0019-6479 TA - Indian Vet J PG - 1008-15 CY - INDIA IP - 12 VI - 44 JC - GM9 EM - 6809 PMID- 5587776 CU - 88 SO - Indian Vet J 1967 Dec;44(12):1008-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [94 medline neighbors] UI - 68233667 AU - Szyfres B AU - Sulzer CR AU - Galton MM TI - A new leptospiral serotype in the Bataviae serogroup from Argentina. LA - Eng MH - Animal MH - Argentina MH - *Edentata MH - Hemagglutination Tests MH - Leptospira/*classification MH - Tissue Culture MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 680630 DP - 1967 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 344-6 SB - M CY - NETHERLANDS IP - 4 VI - 19 JC - WGJ EM - 6808 PMID- 5585980 SO - Trop Geogr Med 1967 Dec;19(4):344-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [82 medline neighbors] UI - 68153768 AU - Johnson RC AU - Rogers P TI - Metabolism of leptospires. II. The action of 8-azaguanine. LA - Eng MH - Adenine/metabolism MH - Azaguanine/metabolism/*pharmacology MH - Carbon Isotopes MH - Glycine/metabolism MH - Guanine/metabolism MH - Leptospira/*drug effects/metabolism MH - Leptospira interrogans/*drug effects/metabolism MH - Palmitic Acids/metabolism PT - JOURNAL ARTICLE DA - 680428 DP - 1967 Dec IS - 0008-4166 TA - Can J Microbiol PG - 1621-9 SB - M CY - CANADA IP - 12 VI - 13 JC - CJ3 EM - 6806 PMID- 5582206 SO - Can J Microbiol 1967 Dec;13(12):1621-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70090261 AU - Mello MT de AU - Silva DI da TI - [Microdilution test for the serological diagnosis of leptospirosis using commercial antigens] LA - Por MH - *Antigens MH - English Abstract MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*diagnosis MH - Methods MH - Microchemistry PT - JOURNAL ARTICLE DA - 700305 DP - 1967 Dec IS - 0018-5469 TA - Hospital (Rio J) PG - 1877-83 CY - BRAZIL IP - 6 VI - 72 JC - GDB EM - 7004 PMID- 5308478 CU - 90 TT - Prova de microdiluicao para o diagnostico sorologico de leptospirose usando antigenos comerciais. SO - Hospital (Rio J) 1967 Dec;72(6):1877-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68136433 AU - Stalheim OH TI - A toxic factor in Leptospira pomona. LA - Eng MH - Animal MH - Cell Membrane Permeability/drug effects MH - Endotoxins/*toxicity MH - Guinea Pigs MH - In Vitro MH - Leptospira/growth & development/*pathogenicity MH - Macrophages MH - Methods MH - Oxygen Consumption/drug effects PT - JOURNAL ARTICLE DA - 680411 DP - 1967 Nov IS - 0037-9727 TA - Proc Soc Exp Biol Med PG - 412-5 SB - M CY - UNITED STATES IP - 2 VI - 126 JC - PXZ EM - 6805 PMID- 6082707 CU - 90 SO - Proc Soc Exp Biol Med 1967 Nov;126(2):412-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68099000 AU - Finco DR AU - Low DG TI - Endotoxin properties of Leptospira canicola. LA - Eng MH - Animal MH - Biological Assay MH - Blood Platelets MH - Chick Embryo MH - *Endotoxins MH - Female MH - *Leptospira canicola MH - Leukocyte Count MH - Male MH - Mice MH - Rabbits PT - JOURNAL ARTICLE DA - 680226 DP - 1967 Nov IS - 0002-9645 TA - Am J Vet Res PG - 1863-72 SB - M CY - UNITED STATES IP - 127 VI - 28 JC - 40C EM - 6804 RO - M:CNR PMID- 6076572 LR - 870610 SO - Am J Vet Res 1967 Nov;28(127):1863-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 69101789 AU - Brunnerf TI - [Experiences with the administration of "Protex Plus" in the therapy and prevention of distemper, hepatitis contagiosa canis(HCC), and leptospiroses] LA - Ger MH - Animal MH - Antibodies MH - Distemper/*prevention & control MH - Dogs MH - Hepatitis, Animal/*prevention & control MH - Immune Sera/*administration & dosage MH - Leptospirosis/prevention & control/*veterinary PT - JOURNAL ARTICLE DA - 690318 DP - 1967 Nov IS - 0043-535X TA - Wien Tierarztl Monatsschr PG - 754-5 CY - AUSTRIA IP - 11 VI - 54 JC - XOZ EM - 6905 PMID- 5632764 CU - 86 TT - Erfahrungen mit der Anwendung von "Protex Plus" zur Therapie und Prophylaxe von Staupe, HCC und Leptospirosen. SO - Wien Tierarztl Monatsschr 1967 Nov;54(11):754-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 70003429 AU - Vishniakov IF AU - Sosov RF TI - [Asymptomatic course of leptospirosis in cattle] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 691129 DP - 1967 Nov IS - 0042-4846 TA - Veterinariia PG - 56-8 CY - USSR IP - 11 VI - 44 JC - XCC EM - 7001 PMID- 5630017 CU - 85 TT - O bessimptommnom techenii leptospiroza u krupnogo rogatogo skota. SO - Veterinariia 1967 Nov;44(11):56-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70003423 AU - Bolotskii IA TI - [The effect of streptomycin on immunological reactions in pigs in leptospirosis] LA - Rus MH - Animal MH - Immunity/*drug effects MH - Leptospirosis/*veterinary MH - Streptomycin/*therapeutic use MH - *Swine MH - Swine Diseases/*drug therapy PT - JOURNAL ARTICLE DA - 691129 DP - 1967 Nov IS - 0042-4846 TA - Veterinariia PG - 37-8 CY - USSR IP - 11 VI - 44 JC - XCC EM - 7001 PMID- 5630013 CU - 85 TT - Vliianie streptomitsina na immunologicheskie reaktsii u porosiat pri leptospiroze. SO - Veterinariia 1967 Nov;44(11):37-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68322114 AU - Hoeden J van der AU - Shenberg E AU - Torten M TI - The epidemiological complexity of Leptospira canicola infection of man and animals in Israel. LA - Eng MH - Animal MH - Carnivora MH - Cattle MH - Cattle Diseases/*epidemiology MH - Dog Diseases/*epidemiology MH - Dogs MH - Epidemiology MH - Horse Diseases/*epidemiology MH - Horses MH - Human MH - Israel MH - Leptospira canicola MH - Leptospirosis/*epidemiology MH - Rodent Diseases/*epidemiology MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 680829 DP - 1967 Nov-Dec IS - 0021-2180 TA - Isr J Med Sci PG - 880-4 SB - M CY - ISRAEL IP - 6 VI - 3 JC - GY0 EM - 6810 PMID- 5627226 CU - 88 SO - Isr J Med Sci 1967 Nov-Dec;3(6):880-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 69225980 AU - Kiktenko VS TI - [Successes in the study of leptospirosis in the USSR during the 50 years of Soviet power] LA - Rus MH - Animal MH - History of Medicine, 20th Cent. MH - Human MH - Leptospirosis/*history MH - USSR PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 690818 DP - 1967 Nov TA - Zh Mikrobiol Epidemiol Immunobiol PG - 55-60 SB - M CY - USSR IP - 11 VI - 44 JC - Y9O EM - 6910 PMID- 4892871 CU - 90 TT - Uspekhi v izuchenii leptospirozov v SSSR za 50 let Sovetskoi vlasti. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Nov;44(11):55-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 68098976 AU - Stalheim OH TI - Vaccination against leptospirosis: protection of hamsters and swine against renal leptospirosis by killed but intact gamma-irradiated or dihydrostreptomycin-exposed Leptospira pomona. LA - Eng MH - Animal MH - Dihydrostreptomycin Sulfate/*pharmacology MH - *Hamsters MH - Leptospira/isolation & purification/*radiation effects MH - Leptospirosis/prevention & control/*veterinary MH - Rodent Diseases/*prevention & control MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 680226 DP - 1967 Nov IS - 0002-9645 TA - Am J Vet Res PG - 1671-6 SB - M CY - UNITED STATES IP - 127 VI - 28 JC - 40C EM - 6804 RO - M:CNR PMID- 4169487 LR - 870610 CU - 95 SO - Am J Vet Res 1967 Nov;28(127):1671-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68049206 AU - Stoenner HG TI - Leptospiral abortion of beef cattle caused by Leptospira pomona and Leptospira hardjo. LA - Eng MH - Abortion, Veterinary/*etiology MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*immunology MH - Female MH - Leptospirosis/complications/immunology/*veterinary MH - Male MH - Pregnancy PT - JOURNAL ARTICLE DA - 680119 DP - 1967 Oct 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1087-90 SB - M CY - UNITED STATES IP - 8 VI - 151 JC - HAV EM - 6802 PMID- 6069990 CU - 85 SO - J Am Vet Med Assoc 1967 Oct 15;151(8):1087-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68051832 AU - Prescott CW TI - Field observations on leptospirosis of cattle in north-eastern New South Wales. LA - Eng MH - Animal MH - Australia MH - Cattle MH - Cattle Diseases/*epidemiology MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 680121 DP - 1967 Oct IS - 0005-0423 TA - Aust Vet J PG - 461-5 SB - M CY - AUSTRALIA IP - 10 VI - 43 JC - 9IE EM - 6802 PMID- 6070050 CU - 88 SO - Aust Vet J 1967 Oct;43(10):461-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68049407 AU - Nityananda K TI - Leptospirosis--serological survey of occupational groups in Ceylon. LA - Eng MH - Human MH - *Occupational Diseases MH - Sri Lanka MH - Weil's Disease/blood/*epidemiology/etiology PT - JOURNAL ARTICLE DA - 680119 DP - 1967 Oct IS - 0022-5304 TA - J Trop Med Hyg PG - 250-4 SB - M CY - ENGLAND IP - 10 VI - 70 JC - KAV EM - 6802 PMID- 6059488 CU - 88 SO - J Trop Med Hyg 1967 Oct;70(10):250-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70010468 AU - Liubashenko SIa AU - Kostrikina LG AU - Deripasko PG AU - Kornelaeva RP AU - Loginov IA AU - Beliaev VM AU - Korolev VM AU - Slugin VS AU - Gavrilova LD TI - [Test of a concentrated polyvalent adsorbate vaccine against leptospirosis] LA - Rus MH - Animal MH - Animal Diseases/*prevention & control MH - Cattle MH - Cattle Diseases/prevention & control MH - Foxes MH - Horse Diseases/prevention & control MH - Horses MH - Leptospirosis/*veterinary MH - Sheep MH - Sheep Diseases/prevention & control MH - Swine MH - Swine Diseases/prevention & control MH - USSR MH - *Vaccines PT - JOURNAL ARTICLE DA - 691203 DP - 1967 Oct IS - 0042-4846 TA - Veterinariia PG - 40-3 CY - USSR IP - 10 VI - 44 JC - XCC EM - 7001 PMID- 5630128 CU - 85 TT - Ispytanie kontsentrirovannoi polivalentnoi sorbirovannoi vaktsiny protiv leptospiroza. SO - Veterinariia 1967 Oct;44(10):40-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [150 medline neighbors] UI - 68154650 AU - Anderson LJ TI - Experimental reproduction of canine interstitial nephritis. LA - Eng MH - Animal MH - *Dog Diseases MH - *Dogs MH - Injections, Intraperitoneal MH - Kidney/pathology MH - Leptospira canicola/isolation & purification/*pathogenicity MH - *Leptospirosis MH - Nephritis, Interstitial/pathology/*veterinary MH - Uremia/etiology MH - Virulence PT - JOURNAL ARTICLE DA - 680428 DP - 1967 Oct IS - 0021-9975 TA - J Comp Pathol PG - 413-8 SB - M CY - ENGLAND IP - 4 VI - 77 JC - HVB EM - 6806 PMID- 5582484 SO - J Comp Pathol 1967 Oct;77(4):413-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68364849 AU - Bhatnagar RK AU - Sant MV AU - Jhala HI TI - Prevalence of leptospirosis in Bombay. Studies in man and animals. LA - Eng MH - Animal MH - Buffaloes MH - Cats MH - *Disease Reservoirs MH - Dogs MH - Haplorhini MH - Hepatitis A/microbiology MH - Human MH - India MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology/veterinary MH - Rabbits MH - Rats MH - Serodiagnosis MH - Swine PT - JOURNAL ARTICLE DA - 681005 DP - 1967 Oct IS - 0019-5448 TA - Indian J Pathol Bacteriol PG - 324-31 CY - INDIA IP - 4 VI - 10 JC - GKJ EM - 6811 PMID- 4970101 CU - 91 SO - Indian J Pathol Bacteriol 1967 Oct;10(4):324-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 69254764 AU - Kosmachevskii VV AU - Chernousova AV TI - [The growth in knowledge of the pathogenesis and clinical picture of leptospirosis in the USSR] LA - Rus MH - Animal MH - Epidemiology/*history MH - History of Medicine, 19th Cent. MH - History of Medicine, 20th Cent. MH - Human MH - Leptospirosis/diagnosis/etiology/*history MH - Microbiology/*history MH - Russia (Pre-1917) MH - USSR PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 690920 DP - 1967 Oct TA - Zh Mikrobiol Epidemiol Immunobiol PG - 13-7 SB - M CY - USSR IP - 10 VI - 44 JC - Y9O EM - 6911 PMID- 4895151 CU - 90 TT - Razvitie ucheniia o patogeneze i klinike leptospiroznykh zabolevanii v SSSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Oct;44(10):13-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 68355476 AU - Schroder HD AU - Senf W TI - [Fluorescence serology for Leptospira hyos detection in pigs] LA - Ger MH - Abortion, Veterinary/*diagnosis MH - Animal MH - Female MH - Fluorescent Antibody Technique MH - Leptospirosis/diagnosis/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 680916 DP - 1967 Oct 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 771-3 CY - GERMANY, EAST IP - 19 VI - 22 JC - NGV EM - 6811 PMID- 4874706 CU - 90 TT - Fluoreszenz-serologischer Nachweis von Leptospira hyos beim Schwein. SO - Monatsh Veterinarmed 1967 Oct 1;22(19):771-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [215 medline neighbors] UI - 68000724 AU - Parry WH TI - Leptospirosis. LA - Eng MH - *Leptospirosis PT - JOURNAL ARTICLE DA - 671212 DP - 1967 Sep 22 IS - 0029-6589 TA - Nurs Times PG - 1272-3 CY - ENGLAND IP - 38 VI - 63 JC - O9U EM - 6801 PMID- 6048051 SO - Nurs Times 1967 Sep 22;63(38):1272-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70288398 AU - Kats LN AU - Konstantinova ND AU - Anan'in VV TI - [Electron microscopic studies of the Leptospira cyst] LA - Rus MH - Leptospira/*cytology MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 701103 DP - 1967 Sep 21 IS - 0002-3264 TA - Dokl Akad Nauk SSSR PG - 710-1 SB - M CY - USSR IP - 3 VI - 176 JC - EBK EM - 7012 PMID- 5623854 TT - Elektronnomikroskopicheskoe issledovanie tsist u leptospir. SO - Dokl Akad Nauk SSSR 1967 Sep 21;176(3):710-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68362712 AU - Konrad J AU - Vosta J TI - [Studies in the occurrence of counter-substances against leptospira in horses and cattle within the complex of internal diseases] LA - Ger MH - Animal MH - Cattle MH - Cattle Diseases/*immunology MH - Horse Diseases/*immunology MH - Horses MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 681003 DP - 1967 Sep 15 IS - 0005-9366 TA - Berl Munch Tierarztl Wochenschr PG - 348-50 CY - GERMANY, WEST IP - 18 VI - 80 JC - 9Q8 EM - 6811 PMID- 5627963 CU - 85 TT - Studien uber das Vorkommen von Antikorpern gegen Leptospiren bei Pferden und Rindern in der CSSR. SO - Berl Munch Tierarztl Wochenschr 1967 Sep 15;80(18):348-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68052633 AU - Nicosia A AU - Ioli A TI - [Experimental uveitis in leptospirosis (preliminary research)] LA - Fre MH - Agglutination Tests MH - Animal MH - Antibody Formation MH - Leptospirosis/*complications/enzymology MH - Rabbits MH - Uveitis/enzymology/*etiology PT - JOURNAL ARTICLE DA - 680121 DP - 1967 Sep IS - 0003-4371 TA - Ann Ocul (Paris) PG - 988-92 SB - M CY - FRANCE IP - 9 VI - 200 JC - 5OU EM - 6802 PMID- 6060429 TT - Uveite experimentale de la leptospirose (recherches preliminaires) SO - Ann Ocul (Paris) 1967 Sep;200(9):988-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 68014417 AU - Topciu V AU - Levin S TI - Serological evidence of leptospiral infections in animals and their attendants on live-stock farms. LA - Eng MH - Animal MH - Antibodies MH - Cattle MH - Dogs MH - Hemagglutination Tests MH - Horses MH - Human MH - Leptospira MH - Leptospira canicola MH - Leptospira interrogans MH - Leptospirosis/*immunology MH - Sheep MH - Swine MH - Zoonoses/*immunology PT - JOURNAL ARTICLE DA - 671221 DP - 1967 Sep IS - 0041-3232 TA - Trop Geogr Med PG - 212-20 SB - M CY - NETHERLANDS IP - 3 VI - 19 JC - WGJ EM - 6801 PMID- 6054494 SO - Trop Geogr Med 1967 Sep;19(3):212-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69256743 AU - Maliavin AG AU - Solov'eva VS AU - Shupliko AN TI - [Specific prevention of leptospirosis in agricultural and industrial animals] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - Leptospirosis/*veterinary MH - *Rabbits MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 690922 DP - 1967 Sep IS - 0042-4846 TA - Veterinariia PG - 61-4 CY - USSR IP - 9 VI - 44 JC - XCC EM - 6911 PMID- 5629630 CU - 85 TT - Spetsificheskaia profilaktika leptospiroza sel'skokhoziaistvennykh i promyslovykh zhivotnykh. SO - Veterinariia 1967 Sep;44(9):61-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69195337 AU - Wiesmann E AU - Schallibaum R TI - [Statistical contribution to leptospirosis of hogs from the region of Eastern Switzerland] LA - Ger MH - Animal MH - Leptospira/*isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Swine MH - Swine Diseases/*epidemiology MH - Switzerland PT - JOURNAL ARTICLE DA - 690709 DP - 1967 Sep IS - 0036-7281 TA - Schweiz Arch Tierheilkd PG - 469-70 CY - SWITZERLAND IP - 9 VI - 109 JC - UE5 EM - 6908 PMID- 5629479 CU - 88 TT - Statisticher Beitrag zur Leptospirose bei Schweinen aus der Region Ostschweiz. SO - Schweiz Arch Tierheilkd 1967 Sep;109(9):469-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 68355464 AU - Wittig W AU - Horsch F AU - Zimmerhackel W AU - Haase H TI - [Leptospira pomona infection in young cattle] LA - Ger MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Germany, East MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 680916 DP - 1967 Sep 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 684-7 CY - GERMANY, EAST IP - 17 VI - 22 JC - NGV EM - 6811 PMID- 5627645 CU - 88 TT - Leptospira-pomona-Infektion bei Jungrindern. SO - Monatsh Veterinarmed 1967 Sep 1;22(17):684-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68322739 AU - Teodorovici G AU - Ivan A AU - Oana C AU - Zvoristeanu V AU - Burduja A AU - Popa I AU - Beldiman V AU - Pieptu P AU - Bejenaru C AU - Luca A AU - Sirmon E AU - Badea A AU - Pavel S TI - [Study of cases of leptospirosis in the Tutova River basin (Rumania)] LA - Fre MH - Agglutination Tests MH - Animal MH - *Antibodies MH - Cattle MH - Cattle Diseases/epidemiology MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - Leptospira/immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*epidemiology/veterinary MH - Romania MH - Seasons MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 680830 DP - 1967 Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 579-88 CY - ROMANIA IP - 3 VI - 26 JC - 8EM EM - 6810 PMID- 5627259 CU - 88 TT - Etude des cas de leptospirose dans le bassin de la Tutova (Roumanie) SO - Arch Roum Pathol Exp Microbiol 1967 Sep;26(3):579-88 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68322736 AU - Nicolesco M AU - Lelutiu C TI - [Diagnosis through complement fixation reaction using a single antigen in the detection of animal leptospiroses] LA - Fre MH - Animal MH - *Antigens MH - Cattle MH - Cattle Diseases/diagnosis MH - Comparative Study MH - Complement Fixation Tests MH - Dog Diseases/diagnosis MH - Dogs MH - Horse Diseases/diagnosis MH - Horses MH - Leptospirosis/diagnosis/*veterinary MH - Rabbits MH - Serodiagnosis MH - Swine MH - Swine Diseases/diagnosis PT - JOURNAL ARTICLE DA - 680830 DP - 1967 Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 557-64 CY - ROMANIA IP - 3 VI - 26 JC - 8EM EM - 6810 PMID- 5627258 CU - 85 TT - Diagnostic par la reaction de fixation du complement a l'aide d'un antigene unique dans le decelement des leptospiroses animales. SO - Arch Roum Pathol Exp Microbiol 1967 Sep;26(3):557-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 68231313 AU - Radulescu P AU - Dobrescu A TI - [Epidemiological-epizootic considerations on an outbreak of leptospirosis icterohemorrhagica] LA - Rum MH - Adult MH - Animal MH - *Animals, Laboratory MH - Human MH - *Laboratory Infection MH - Middle Age MH - *Occupational Diseases MH - Rats MH - *Rodent Diseases MH - Romania MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 680625 DP - 1967 Sep-Oct IS - 0026-2609 TA - Microbiol Parazitol Epidemiol (Bucur) PG - 451-4 CY - ROMANIA IP - 5 VI - 12 JC - MXQ EM - 6808 PMID- 5626300 CU - 88 TT - Consideratii epidemo-epizootice in legatura cu un episod de leptospiroza icterohemoragica. SO - Microbiol Parazitol Epidemiol (Bucur) 1967 Sep-Oct;12(5):451-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 68084707 AU - Torten M AU - Ben-Efraim S AU - Shenberg E AU - Beemer AM AU - Van Der Hoeden J TI - Experimental induction of ocular reaction resembling post leptospiral ophthalmia and its relation to skin reactions and circulating antibodies. LA - Eng MH - Animal MH - *Antibodies MH - Antigen-Antibody Reactions MH - Dogs MH - Endophthalmitis/*etiology/*immunology MH - Hypersensitivity, Delayed/*etiology MH - Leptospirosis/*complications MH - Skin Tests PT - JOURNAL ARTICLE DA - 680210 DP - 1967 Sep IS - 0009-9104 TA - Clin Exp Immunol PG - 573-80 SB - M CY - ENGLAND IP - 5 VI - 2 JC - DD7 EM - 6803 PMID- 5299575 CU - 89 SO - Clin Exp Immunol 1967 Sep;2(5):573-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 68014802 AU - Coghlan JD AU - Lumsden WH AU - McNeillage GJ TI - Low-temperature preservation of Leptospira, preliminary communication. LA - Eng MH - *Bacteriological Techniques MH - Freezing MH - Glycerin/pharmacology MH - *Leptospira MH - Preservation, Biological PT - JOURNAL ARTICLE DA - 671221 DP - 1967 Sep IS - 0022-1724 TA - J Hyg (Lond) PG - 373-9 SB - M CY - ENGLAND IP - 3 VI - 65 JC - IEF EM - 6801 PMID- 4861498 CU - 90 SO - J Hyg (Lond) 1967 Sep;65(3):373-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70257839 AU - Kats LN AU - Konstantinova ND TI - [Ultrastructure of the axial filament in leptospira] LA - Rus MH - Leptospira/*anatomy & histology MH - Microscopy, Electron MH - Organoids PT - JOURNAL ARTICLE DA - 700928 DP - 1967 Aug 21 IS - 0002-3264 TA - Dokl Akad Nauk SSSR PG - 1389-91 SB - M CY - USSR IP - 6 VI - 175 JC - EBK EM - 7011 PMID- 5623423 TT - O submikroskopicheskoi strukture osevoi niti u leptospir. SO - Dokl Akad Nauk SSSR 1967 Aug 21;175(6):1389-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 69143520 AU - Garofalo P AU - Cattaneo G TI - [Description of a case of leptospirosis (probably due to L. icterohemorrhagiae) in a 2-months-old infant] LA - Ita MH - Animal MH - Female MH - Human MH - Infant MH - Leptospira interrogans/*isolation & purification MH - Milk/microbiology MH - Weil's Disease/etiology/*pathology PT - JOURNAL ARTICLE DA - 690508 DP - 1967 Aug 4 IS - 0026-4946 TA - Minerva Pediatr PG - 1464-6 CY - ITALY IP - 31 VI - 19 JC - NAM EM - 6906 PMID- 5632942 CU - 86 TT - Descrizione di un caso di leptospirosi (da probabile L. icterohaemorragiae) in una lattante di due mesi. SO - Minerva Pediatr 1967 Aug 4;19(31):1464-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68093207 AU - Burger G AU - Fuchs GH TI - Increase in growth rate of leptospirae by zinc nitrate. LA - Eng MH - Leptospira/*drug effects/growth & development MH - Zinc/*pharmacology PT - JOURNAL ARTICLE DA - 680215 DP - 1967 Aug IS - 0021-8847 TA - J Appl Bacteriol PG - 333-5 CY - ENGLAND IP - 2 VI - 30 JC - HDJ EM - 6803 PMID- 6073989 SO - J Appl Bacteriol 1967 Aug;30(2):333-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68003710 AU - Francis J TI - Zoonoses and public health. LA - Eng MH - Animal MH - Brucellosis/veterinary MH - Food Inspection MH - Human MH - Leptospirosis MH - Meat MH - Ornithosis MH - Plague MH - *Public Health MH - Q Fever MH - Rabbits MH - Salmonella Food Poisoning MH - Salmonella Infections, Animal MH - Tuberculosis/veterinary MH - Typhus, Epidemic Louse-Borne MH - *Zoonoses PT - JOURNAL ARTICLE DA - 671214 DP - 1967 Aug IS - 0005-0423 TA - Aust Vet J PG - 311-28 SB - M CY - AUSTRALIA IP - 8 VI - 43 JC - 9IE EM - 6801 PMID- 6069198 CU - 85 SO - Aust Vet J 1967 Aug;43(8):311-28 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69103660 AU - Kubin G AU - Kolbl O TI - [Serological studies of abortion cases in bang-negative cattle in Carinthia and Salzburg] LA - Ger MH - Abortion, Veterinary/*immunology MH - Agglutination Tests MH - Animal MH - Austria MH - Cattle MH - Cattle Diseases/*immunology MH - Chlamydia Infections/*veterinary MH - Complement Fixation Tests MH - Female MH - Leptospirosis/*veterinary MH - Neutralization Tests MH - Pregnancy PT - JOURNAL ARTICLE DA - 690319 DP - 1967 Aug IS - 0043-535X TA - Wien Tierarztl Monatsschr PG - 526-36 CY - AUSTRIA IP - 8 VI - 54 JC - XOZ EM - 6905 PMID- 5632774 CU - 86 TT - Serologische Untersuchungen von Abortusfallen bei bangnegativen Rindern in Karnten und Salzburg. SO - Wien Tierarztl Monatsschr 1967 Aug;54(8):526-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69208461 AU - Drankin DI AU - Markina EG AU - Rumiantseva EV TI - [On the epidemiology of leptospirosis in the Saratovsk region] LA - Rus MH - Animal MH - Cattle MH - Human MH - Leptospira/isolation & purification MH - Leptospira canicola/isolation & purification MH - Leptospira interrogans/isolation & purification MH - Leptospirosis/*epidemiology/microbiology/*veterinary MH - Sheep MH - Sheep Diseases MH - Swine MH - Swine Diseases MH - USSR MH - Zoonoses PT - JOURNAL ARTICLE DA - 690802 DP - 1967 Aug TA - Zh Mikrobiol Epidemiol Immunobiol PG - 133 SB - M CY - USSR IP - 8 VI - 44 JC - Y9O EM - 6909 PMID- 5629535 CU - 89 TT - K epidemiologii leptospirozov v saratovskoi oblasti. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Aug;44(8):133 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68327132 AU - Heneberg D AU - Morelj M AU - Heneberg N AU - Mikes M AU - Dokovic V AU - Borcic B AU - Hrabar A AU - Isgum M AU - Dordevic Z TI - [1st results of the investigation study of natural foci of tularemia in the region of Sisak, Gusce and Popovaca] LA - Scc MH - Animal MH - Disease Reservoirs MH - Francisella tularensis/isolation & purification MH - Human MH - Leptospira interrogans/isolation & purification MH - Mice MH - Rabbits MH - Rodent Diseases MH - Tularemia/*epidemiology/microbiology MH - Yugoslavia MH - Zoonoses PT - JOURNAL ARTICLE DA - 680906 DP - 1967 Aug IS - 0024-3477 TA - Lijec Vjesn PG - 591-600 CY - YUGOSLAVIA IP - 8 VI - 89 JC - L6C EM - 6810 PMID- 5627341 CU - 88 TT - Prvi rezultati istrazivanja prirodnih zarista tularemije na podrucju Sisak, Gusci i Popovaca. SO - Lijec Vjesn 1967 Aug;89(8):591-600 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70008458 AU - Shatrovap AU - Kirpichev AF TI - [Leptospirosis of livestock in certain districts of Kazakhstan] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - Kazakhstan MH - Leptospirosis/*veterinary MH - Swine MH - Swine Diseases/*prevention & control PT - JOURNAL ARTICLE DA - 691202 DP - 1967 Aug IS - 0042-4846 TA - Veterinariia PG - 60-1 CY - USSR IP - 8 VI - 44 JC - XCC EM - 7001 PMID- 4242031 CU - 92 TT - Leptospiroz zhivotnykh v nekotorykh oblastiakh Kazakhstana. SO - Veterinariia 1967 Aug;44(8):60-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70008450 AU - Sviridenko VF TI - [The fluorescent antibody method in the diagnosis of leptospirosis in sheep] LA - Rus MH - Animal MH - *Fluorescent Antibody Technique MH - Kyrgyzstan MH - Leptospirosis/*veterinary MH - Methods MH - Sheep MH - Sheep Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 691202 DP - 1967 Aug IS - 0042-4846 TA - Veterinariia PG - 48-9 CY - USSR IP - 8 VI - 44 JC - XCC EM - 7001 PMID- 4242028 CU - 92 TT - Metod fluorestsiruiushchikh antitel pri diagnostike leptospiroza u ovets. SO - Veterinariia 1967 Aug;44(8):48-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68054202 AU - Mierzejewska I AU - Radominska I AU - Cybulska M TI - [A case of leptospirosis due to "hebdomadis" group of leptospira] LA - Pol MH - Case Report MH - Chloramphenicol/*therapeutic use MH - Human MH - Leptospirosis/*microbiology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 680121 DP - 1967 Jul 24 IS - 0032-3756 TA - Pol Tyg Lek PG - 760-1 CY - POLAND IP - 20 VI - 22 JC - PBY EM - 6802 PMID- 6061137 TT - Przypadek leptospirozy wywolanej leptospirami z grupy "hebdomadis". SO - Pol Tyg Lek 1967 Jul 24;22(20):760-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68088008 AU - Bejenaru C AU - Burduja A AU - Sirmon E AU - Decus V AU - Pavel S AU - Antohi D TI - [Immunobiological relationships between pathogenic and saprophytic leptospiras] LA - Rum MH - Animal MH - Antibodies/*analysis MH - Antigens/*analysis MH - Guinea Pigs MH - Leptospira/*immunology/*pathogenicity MH - Leptospirosis/*immunology MH - Rabbits MH - Swine PT - JOURNAL ARTICLE DA - 680213 DP - 1967 Jul-Sep IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 657-63 CY - ROMANIA IP - 3 VI - 71 JC - SHP EM - 6803 PMID- 6065598 TT - Relatii imunobiologice intre leptospirele patogene si cele saprofite. SO - Rev Med Chir Soc Med Nat Iasi 1967 Jul-Sep;71(3):657-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 67175450 AU - Johnson RC AU - Harris VG TI - Differentiation of pathogenic and saprophytic letospires. I. Growth at low temperatures. LA - Eng MH - Leptospira/*growth & development/isolation & purification MH - Temperature PT - JOURNAL ARTICLE DA - 670902 DP - 1967 Jul IS - 0021-9193 TA - J Bacteriol PG - 27-31 SB - M CY - UNITED STATES IP - 1 VI - 94 JC - HH3 EM - 6710 PMID- 6027998 SO - J Bacteriol 1967 Jul;94(1):27-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 69001671 AU - Wiesmann E TI - [Leptospirosis of cattle, sheep, goat and swine] LA - Ger MH - Animal MH - Cattle MH - *Cattle Diseases MH - *Goats MH - Leptospirosis/*veterinary MH - Sheep MH - *Sheep Diseases MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 681120 DP - 1967 Jul IS - 0036-7281 TA - Schweiz Arch Tierheilkd PG - 386-91 CY - SWITZERLAND IP - 7 VI - 109 JC - UE5 EM - 6901 PMID- 5628622 CU - 85 TT - Die Leptospirosen bei Rind, Schaf, Ziege und Schwein. SO - Schweiz Arch Tierheilkd 1967 Jul;109(7):386-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 68400904 AU - Kaplan S AU - Barroso AO TI - [Leptospirosis by L. canicola] LA - Por MH - Adolescence MH - Case Report MH - Human MH - Jaundice/etiology MH - Leptospirosis/*complications MH - Male MH - Treponema/pathogenicity PT - JOURNAL ARTICLE DA - 681025 DP - 1967 Jul IS - 0018-5469 TA - Hospital (Rio J) PG - 215-9 CY - BRAZIL IP - 1 VI - 72 JC - GDB EM - 6812 PMID- 5302628 CU - 89 TT - Leptospirose por L. canicola. SO - Hospital (Rio J) 1967 Jul;72(1):215-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68099889 AU - Plesko I AU - Novakova Z TI - [New findings from the study of leptospirosis reservoirs in Southwestern Slovakia] LA - Slo MH - Animal MH - Czechoslovakia MH - *Disease Reservoirs MH - Leptospirosis/*veterinary MH - Rodent Diseases/*epidemiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 680226 DP - 1967 Jun 30 IS - 0006-9248 TA - Bratisl Lek Listy PG - 115-20 CY - CZECHOSLOVAKIA IP - 2 VI - 48 JC - B5N EM - 6804 PMID- 5624665 CU - 88 TT - Nove poznatky zo sledovania rezervoarov leptospiroz na juhozapadnom Slovensku. SO - Bratisl Lek Listy 1967 Jun 30;48(2):115-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68011665 AU - Diesch SL AU - McCulloch WF AU - Braun JL TI - Experimental leptospirosis in frogs. LA - Eng MH - Animal MH - *Antibody Formation MH - Anura MH - Leptospirosis/*immunology PT - JOURNAL ARTICLE DA - 671218 DP - 1967 Jun 10 IS - 0028-0836 TA - Nature PG - 1139-40 SB - M CY - ENGLAND IP - 93 VI - 214 JC - NSC EM - 6801 PMID- 6053083 SO - Nature 1967 Jun 10;214(93):1139-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [117 medline neighbors] UI - 67165988 AU - Cameron JS AU - Ogg C AU - Trounce JR TI - Peritoneal dialysis in hypercatabolic acute renal failure. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Burns/complications MH - Child, Preschool MH - Female MH - Gangrene/complications MH - Heart Surgery/adverse effects MH - Human MH - Kidney Failure, Acute/etiology/*therapy MH - Leptospirosis/complications MH - Male MH - Middle Age MH - *Peritoneal Dialysis MH - Postoperative Complications MH - Urea/metabolism MH - Uremia/complications MH - Vascular Surgery/adverse effects PT - JOURNAL ARTICLE DA - 670803 DP - 1967 Jun 3 IS - 0140-6736 TA - Lancet PG - 1188-91 SB - A SB - M CY - ENGLAND IP - 501 VI - 1 JC - L0S EM - 6709 PMID- 4165133 CU - 95 SO - Lancet 1967 Jun 3;1(501):1188-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69238897 AU - Kir'ianov EA AU - Kurdiukov VG TI - [Leptospirosis among animals on Sakhalin] LA - Rus MH - Animal MH - Animal Diseases/diagnosis/*epidemiology/etiology MH - Cattle MH - Cattle Diseases/*epidemiology MH - Disease Reservoirs/*epidemiology/etiology MH - Dog Diseases/*epidemiology MH - Dogs MH - English Abstract MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/diagnosis/*epidemiology/etiology MH - *Mink MH - Siberia MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 690904 DP - 1967 Jun TA - Zh Mikrobiol Epidemiol Immunobiol PG - 59-62 SB - M CY - USSR IP - 6 VI - 44 JC - Y9O EM - 6910 PMID- 5629604 CU - 89 TT - Leptospiroz zhivotnykh na sakhaline. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Jun;44(6):59-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [178 medline neighbors] UI - 69238874 AU - Nazarova ZIa AU - Turovskaia LI AU - Levoshin OA TI - [Epidemiologic characteristics of "bathing" outbreaks of anicteric leptospirosis] LA - Rus MH - Animal MH - Animal Diseases/*epidemiology MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Reservoirs/*epidemiology MH - Human MH - Leptospirosis/*etiology MH - Siberia MH - Swine MH - Swine Diseases/epidemiology MH - *Water Pollution PT - JOURNAL ARTICLE DA - 690904 DP - 1967 Jun TA - Zh Mikrobiol Epidemiol Immunobiol PG - 130-1 SB - M CY - USSR IP - 6 VI - 44 JC - Y9O EM - 6910 PMID- 5629602 CU - 89 TT - Epidemiologicheskaia kharakteristika kupalnykh vspyshek bezzheltushnogo leptospiroza. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Jun;44(6):130-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68311933 AU - Levin S AU - Topciu V AU - Gluhovski N TI - [Considerations concerning certain aspects of the immune response of bovine leptospirosis] LA - Fre MH - Agglutination Tests MH - Animal MH - *Antibody Formation MH - Cattle MH - Cattle Diseases/*immunology MH - Disease Outbreaks/veterinary MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 680815 DP - 1967 Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 411-7 CY - ROMANIA IP - 2 VI - 26 JC - 8EM EM - 6810 PMID- 5626820 CU - 85 TT - Considerations concernant certains aspects de la reponse immunitaire dans la leptospirose bovine. SO - Arch Roum Pathol Exp Microbiol 1967 Jun;26(2):411-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 68311922 AU - Topciu V AU - Levin S AU - Dragan J AU - Radu I TI - [Serological investigation on the spread of leptospirotic infection in the personnel charged with animal care in various zootechnical units in Rumania] LA - Fre MH - *Agricultural Workers' Diseases MH - Animal MH - Antibodies MH - Disease Reservoirs MH - Horses MH - Human MH - Leptospirosis/epidemiology/*immunology MH - Romania MH - Swine PT - JOURNAL ARTICLE DA - 680815 DP - 1967 Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 309-18 CY - ROMANIA IP - 2 VI - 26 JC - 8EM EM - 6810 PMID- 5626819 CU - 88 TT - Enquete serologique concernant la diffusion de l'infection leptospirotique chez le personnel affecte au soin des animaux dans quelques unites zootechniques de Roumanie. SO - Arch Roum Pathol Exp Microbiol 1967 Jun;26(2):309-18 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 69036981 AU - Shelkovskaia GA TI - [Treatment of Q fever and swamp fever with reopirin or butadion and antibiotics] LA - Rus MH - Adolescence MH - Adult MH - Chlortetracycline/therapeutic use MH - Comparative Study MH - Female MH - Human MH - Leptospirosis/*drug therapy MH - Male MH - Middle Age MH - Phenylbutazone/*therapeutic use MH - Q Fever/*drug therapy PT - JOURNAL ARTICLE DA - 690108 DP - 1967 Jun IS - 0049-6804 TA - Vrach Delo PG - 114-5 CY - USSR VI - 6 JC - XLS EM - 6902 PMID- 5602770 TT - Lechenke reopirionom ili butadioni, i antibiotikami bol'nykh Ky- kikhoradkoi i vodnoi likhoradkoi. SO - Vrach Delo 1967 Jun;6:114-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 70007479 AU - Petrov VF AU - But'ianov DD AU - Shpakovskii AA AU - Stoliarov NI TI - [Simultaneous vaccination of swine against several diseases] LA - Rus MH - Animal MH - Erysipelothrix Infections/prevention & control MH - Hog Cholera/prevention & control MH - Leptospirosis/prevention & control MH - Paratyphoid Fever/prevention & control MH - Pasteurella Infections/prevention & control MH - Swine MH - Swine Diseases/*prevention & control MH - *Vaccination PT - JOURNAL ARTICLE DA - 691202 DP - 1967 Jun IS - 0042-4846 TA - Veterinariia PG - 51-7 CY - USSR IP - 6 VI - 44 JC - XCC EM - 7001 PMID- 4981076 CU - 91 TT - Odnovremennaia vaktsinatsiia svinei protiv neskol'kikh boleznei. SO - Veterinariia 1967 Jun;44(6):51-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 68083341 AU - Migdalska-Kassurowa B TI - [Clinical analysis of 100 cases of various spirochetoses] LA - Pol MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Meningitis/*complications MH - Middle Age MH - *Spirochaeta MH - Typhoid/*complications PT - JOURNAL ARTICLE DA - 680203 DP - 1967 May 8 IS - 0032-3756 TA - Pol Tyg Lek PG - 706-10 CY - POLAND IP - 19 VI - 22 JC - PBY EM - 6803 PMID- 6063799 TT - Analiza kliniczna 100 przypadkow roznych kretkowic. SO - Pol Tyg Lek 1967 May 8;22(19):706-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67215337 AU - Low DG AU - Mather GW AU - Finco DR AU - Anderson NV TI - Long-term studies of renal function in canine leptospirosis. LA - Eng MH - Aminohippuric Acids/urine MH - Animal MH - Blood Flow Velocity MH - Blood Urea Nitrogen MH - Dog Diseases/*physiopathology MH - Dogs MH - Glomerular Filtration Rate MH - Kidney/*physiopathology MH - Leptospirosis/physiopathology/*veterinary PT - JOURNAL ARTICLE DA - 671019 DP - 1967 May IS - 0002-9645 TA - Am J Vet Res PG - 731-9 SB - M CY - UNITED STATES IP - 124 VI - 28 JC - 40C EM - 6711 PMID- 6036373 SO - Am J Vet Res 1967 May;28(124):731-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 67161903 AU - Shenberg E TI - Growth of pathogenic Leptospira in chemically defined media. LA - Eng MH - Culture Media MH - Fatty Acids/metabolism MH - Glycerin/pharmacology MH - Leptospira/*growth & development MH - Leptospira canicola/growth & development MH - Leptospira interrogans/growth & development MH - Polysaccharides, Bacterial/metabolism MH - Thiamine/pharmacology MH - Vitamin B 12/pharmacology PT - JOURNAL ARTICLE DA - 670722 DP - 1967 May IS - 0021-9193 TA - J Bacteriol PG - 1598-606 SB - M CY - UNITED STATES IP - 5 VI - 93 JC - HH3 EM - 6709 PMID- 6025446 SO - J Bacteriol 1967 May;93(5):1598-606 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69290932 AU - Fomin AI AU - Rozumnyi PG AU - Kats MA TI - [Experience in controlling leptospirosis in animals] LA - Rus MH - Animal MH - *Animals, Domestic MH - Cattle MH - Cattle Diseases/prevention & control MH - Horse Diseases/prevention & control MH - Horses MH - Leptospirosis/*veterinary MH - Sheep MH - Sheep Diseases/prevention & control MH - Swine MH - Swine Diseases/prevention & control PT - JOURNAL ARTICLE DA - 691031 DP - 1967 May IS - 0042-4846 TA - Veterinariia PG - 63-5 CY - USSR IP - 5 VI - 44 JC - XCC EM - 6912 PMID- 5629932 CU - 85 TT - Opyt bor'by s leptospirozom zhivotnykh. SO - Veterinariia 1967 May;44(5):63-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69280356 AU - Cacchione RA TI - [Epizootiology, diagnosis and control of bovine, ovine and porcine leptospirosis in the Republic of Argentina] LA - Spa MH - Animal MH - Argentina MH - Cattle MH - *Cattle Diseases MH - Leptospirosis/epidemiology/*veterinary MH - Sheep MH - *Sheep Diseases MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 691021 DP - 1967 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 67-9 CY - FRANCE IP - 1 VI - 68 JC - BR4 EM - 6912 PMID- 5629851 CU - 88 TT - Epizootologia, diagnostico y control de las leptospirosis bovinas, ovinas y porcinas en la Republica Argentina. SO - Bull Off Int Epizoot 1967 May;68(1):67-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69280351 AU - Van der Merwe GF TI - Leptospirosis in cattle, sheep and pigs in the Republic of South Africa. LA - Eng MH - Animal MH - Cattle MH - *Cattle Diseases MH - English Abstract MH - Leptospirosis/epidemiology/*veterinary MH - Sheep MH - *Sheep Diseases MH - South Africa MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 691021 DP - 1967 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 63-6 CY - FRANCE IP - 1 VI - 68 JC - BR4 EM - 6912 PMID- 5629846 CU - 88 SO - Bull Off Int Epizoot 1967 May;68(1):63-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 69280349 TI - Leptospirosis in Thailand. LA - Eng MH - Animal MH - Leptospira/isolation & purification MH - Leptospirosis/epidemiology/*veterinary MH - Thailand PT - JOURNAL ARTICLE DA - 691021 DP - 1967 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 61 CY - FRANCE IP - 1 VI - 68 JC - BR4 EM - 6912 PMID- 5629844 CU - 88 NI - A SO - Bull Off Int Epizoot 1967 May;68(1):61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69280328 AU - Rafyi A AU - Maghami G AU - Niak A TI - [Leptospirosis in sheep and goats] LA - Fre MH - Animal MH - English Abstract MH - *Goats MH - Iran MH - Leptospirosis/epidemiology/*veterinary MH - Sheep MH - *Sheep Diseases PT - JOURNAL ARTICLE DA - 691021 DP - 1967 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 43-59 CY - FRANCE IP - 1 VI - 68 JC - BR4 EM - 6912 PMID- 5629824 CU - 88 TT - Leptospirose ovine et caprine. SO - Bull Off Int Epizoot 1967 May;68(1):43-59 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69280325 AU - Bhattacharya P TI - Epizootiology, diagnosis and control of the leptospirosis of cattle, sheep and pigs in India. LA - Eng MH - Animal MH - Cattle MH - *Cattle Diseases MH - India MH - Leptospirosis/epidemiology/*veterinary MH - Sheep MH - *Sheep Diseases MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 691021 DP - 1967 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 41-2 CY - FRANCE IP - 1 VI - 68 JC - BR4 EM - 6912 PMID- 5629821 CU - 88 SO - Bull Off Int Epizoot 1967 May;68(1):41-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69280306 AU - Popov A AU - Pavlov P TI - [Leptospiroses in animals in Bulgaria] LA - Fre MH - Animal MH - Bulgaria MH - English Abstract MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 691021 DP - 1967 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 27-32 CY - FRANCE IP - 1 VI - 68 JC - BR4 EM - 6912 PMID- 5629803 CU - 88 TT - Les leptospiroses chez lex animaux en Bulgarie. SO - Bull Off Int Epizoot 1967 May;68(1):27-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 69280304 TI - [Epizootiology and diagnosis of leptospirosis in cattle, sheep and swine and the campaign against this disease in Austria] LA - Fre MH - Animal MH - Austria MH - Cattle MH - *Cattle Diseases/prevention & control MH - Leptospirosis/prevention & control/*veterinary MH - Sheep MH - *Sheep Diseases/prevention & control MH - Swine MH - *Swine Diseases/prevention & control PT - JOURNAL ARTICLE DA - 691021 DP - 1967 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 25-6 CY - FRANCE IP - 1 VI - 68 JC - BR4 EM - 6912 PMID- 5629802 CU - 85 NI - A TT - Epizootologie et diagnostic de la leptospirose des bovins, ovins, et porcins et lutte contre cette maladie en Autriche. SO - Bull Off Int Epizoot 1967 May;68(1):25-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69280296 AU - Wiesmann E TI - [Epizootiology, diagnosis and control of bovine, ovine and porcine leptospiroses] LA - Fre MH - Animal MH - Cattle MH - Cattle Diseases/immunology/*prevention & control MH - Leptospirosis/immunology/prevention & control/*veterinary MH - Sheep MH - Sheep Diseases/immunology/*prevention & control MH - Swine MH - Swine Diseases/immunology/*prevention & control PT - JOURNAL ARTICLE DA - 691021 DP - 1967 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 17-24 CY - FRANCE IP - 1 VI - 68 JC - BR4 EM - 6912 PMID- 5629794 CU - 85 TT - Epizootologie, diagnostic et controle des leptospiroses bovines, ovines et porcines. SO - Bull Off Int Epizoot 1967 May;68(1):17-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69264260 AU - Landik GT AU - Moldavskaia AA TI - [Leptospirosis in the Lugansk area in the post-war years] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Reservoirs/*epidemiology MH - Human MH - Leptospirosis/*epidemiology/etiology MH - Rodent Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 691002 DP - 1967 May TA - Zh Mikrobiol Epidemiol Immunobiol PG - 141 SB - M CY - USSR IP - 5 VI - 44 JC - Y9O EM - 6911 PMID- 5629707 CU - 89 TT - Leptospirozy v Luganskoi oblasti v poslevoennye gody. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 May;44(5):141 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 69195334 AU - Schallibaum R TI - [Examination of employees of the abbatoir. (A study from the abattoir in St. Gallen)] LA - Ger MH - *Abattoirs MH - Brucellosis/*epidemiology MH - Human MH - Leptospirosis/*epidemiology MH - Occupational Diseases/*epidemiology MH - Salmonella Infections/*epidemiology MH - Switzerland MH - Toxoplasmosis/*epidemiology PT - JOURNAL ARTICLE DA - 690709 DP - 1967 May IS - 0036-7281 TA - Schweiz Arch Tierheilkd PG - 269-72 CY - SWITZERLAND IP - 5 VI - 109 JC - UE5 EM - 6908 PMID- 5609387 CU - 88 TT - Personaluntersuchung im Schlachthof. (Eine Untersuchung aus dem Schlachthof St. Gallen) SO - Schweiz Arch Tierheilkd 1967 May;109(5):269-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68402356 AU - Engelhardt K TI - [The effect of tetracycline on the antibody formation in letospiroses] LA - Ger MH - Agglutination Tests MH - Animal MH - Antibody Formation/*drug effects MH - Hemolysis MH - Leptospira interrogans MH - Leptospirosis/diagnosis/*immunology MH - Rats MH - Tetracycline/pharmacology/*therapeutic use PT - JOURNAL ARTICLE DA - 681028 DP - 1967 May IS - 0003-9144 TA - Arch Hyg Bakteriol PG - 124-30 SB - M CY - GERMANY, WEST IP - 1 VI - 151 JC - 78G EM - 6812 PMID- 5598576 TT - Die Wirkung von Tetracyclin aud die Antikorperbildung bei Leptospirosen. SO - Arch Hyg Bakteriol 1967 May;151(1):124-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [198 medline neighbors] UI - 68283203 AU - Bakoss P AU - Hruzik J AU - Osvald F TI - [Effect of antibiotic therapy on antibody formation in leptospiral diseases. VII. Antibody formation in human leptospiroses treated with antibiotics] LA - Slo MH - Adolescence MH - Antibiotics/*therapeutic use MH - Antibody Formation/*drug effects MH - Human MH - Leptospira/*drug effects MH - Leptospirosis/drug therapy/*immunology PT - JOURNAL ARTICLE DA - 680807 DP - 1967 May IS - 0006-9248 TA - Bratisl Lek Listy PG - 524-36 CY - CZECHOSLOVAKIA IP - 5 VI - 49 JC - B5N EM - 6809 PMID- 5588874 TT - Vplyv liecby antibiotikami na tvorbu protilatok pri leptospirovych ochoreniach. VII. Tvorba protilatok pri l'udskych leptospirozach liecenych antibiotikami. SO - Bratisl Lek Listy 1967 May;49(5):524-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68040109 AU - Mailloux M TI - [Effect of leptospires on cell cultures] LA - Fre MH - Animal MH - Haplorhini MH - Kidney/cytology MH - Leptospira/*pathogenicity MH - *Tissue Culture PT - JOURNAL ARTICLE DA - 680104 DP - 1967 May IS - 0020-2444 TA - Ann Inst Pasteur (Paris) PG - 664-6 SB - M CY - FRANCE IP - 5 VI - 112 JC - 58Y EM - 6802 PMID- 4964299 CU - 91 TT - Effet des leptospires sur les cultures cellulaires. SO - Ann Inst Pasteur (Paris) 1967 May;112(5):664-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67137862 AU - Hubbert WT TI - Leptospirosis in California. LA - Eng MH - Animal MH - California MH - Cattle MH - Cattle Diseases/epidemiology MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - Leptospirosis/*diagnosis/*epidemiology MH - Sheep MH - Sheep Diseases/epidemiology MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 670701 DP - 1967 May IS - 0094-6214 TA - Public Health Rep PG - 429-33 SB - A SB - M CY - UNITED STATES IP - 5 VI - 82 JC - PHR EM - 6708 PMID- 4960757 CU - 91 SO - Public Health Rep 1967 May;82(5):429-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [194 medline neighbors] UI - 69290931 AU - Dragomir AV TI - [Leptospirosis of agricultural animals in the Moldavian SSR] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Leptospirosis/diagnosis/*veterinary MH - Moldova MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 691031 DP - 1967 May IS - 0042-4846 TA - Veterinariia PG - 61-3 CY - USSR IP - 5 VI - 44 JC - XCC EM - 6912 PMID- 4241604 CU - 92 TT - Leptospiroz sel'skokhoziaistvennykh zhivotnykh v Moldavskoi SSR. SO - Veterinariia 1967 May;44(5):61-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [112 medline neighbors] UI - 67215351 AU - Hubbert WT AU - Miller JN TI - Effect of antibiotic therapy on experimental leptospirosis infection and development of acquired resistance in guinea pigs. LA - Eng MH - Agglutination Tests MH - Animal MH - Dihydrostreptomycin Sulfate/*therapeutic use MH - Guinea Pigs MH - Kidney Diseases/drug therapy MH - Leptospirosis/*drug therapy/*immunology MH - Penicillin G, Procaine/*therapeutic use PT - JOURNAL ARTICLE DA - 671019 DP - 1967 May IS - 0002-9645 TA - Am J Vet Res PG - 861-4 SB - M CY - UNITED STATES IP - 124 VI - 28 JC - 40C EM - 6711 PMID- 4166645 CU - 95 SO - Am J Vet Res 1967 May;28(124):861-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [121 medline neighbors] UI - 67161928 AU - Green SS AU - Goldberg HS TI - Electrophoretic determination of leptospiral enzymes. LA - Eng MH - Amidohydrolases/*analysis MH - Electrophoresis MH - Esterases/*analysis MH - Leptospira/*enzymology MH - Leptospira canicola/enzymology MH - Leptospira interrogans/enzymology MH - Staining PT - JOURNAL ARTICLE DA - 670722 DP - 1967 May IS - 0021-9193 TA - J Bacteriol PG - 1739-40 SB - M CY - UNITED STATES IP - 5 VI - 93 JC - HH3 EM - 6709 PMID- 4164899 CU - 95 SO - J Bacteriol 1967 May;93(5):1739-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 68100585 AU - Kossakiewicz B TI - [Familial incidence of Leptospira canicola infections and Weil's disease and diagnostic difficulties in differentiation from Heine- Medina disease] LA - Pol MH - Adult MH - Case Report MH - Child MH - Child, Preschool MH - Diagnosis, Differential MH - Female MH - Human MH - Leptospirosis/*genetics MH - Male MH - Middle Age MH - Poliomyelitis/*diagnosis MH - Weil's Disease/*genetics PT - JOURNAL ARTICLE DA - 680226 DP - 1967 Apr 15 IS - 0043-5147 TA - Wiad Lek PG - 737-9 CY - POLAND IP - 8 VI - 20 JC - XOA EM - 6804 PMID- 6077334 CU - 88 TT - Rodzinne Zzachorowania na kretkowice psia i chorobe Weila oraz trudnosci diagnostyczne w roznicowaniu z choroba Heinego i Medina. SO - Wiad Lek 1967 Apr 15;20(8):737-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67123501 AU - Diesch SL AU - Crawford RP AU - McCulloch WF AU - Top FH TI - Human leptospirosis acquired from squirrels. LA - Eng MH - Adolescence MH - Adult MH - Animal MH - Fever MH - Human MH - Leptospirosis/*blood MH - Male MH - Nausea MH - Rodentia MH - Zoonoses/*blood PT - JOURNAL ARTICLE DA - 670513 DP - 1967 Apr 13 IS - 0028-4793 TA - N Engl J Med PG - 838-42 SB - A SB - M CY - UNITED STATES IP - 15 VI - 276 JC - NOW EM - 6707 PMID- 6067013 CU - 85 SO - N Engl J Med 1967 Apr 13;276(15):838-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68013760 AU - Beran GW AU - Arambulo PV 3d TI - The incidence of leptospirosis and brucellosis in cattle slaughtered in the Manila abbatoir. LA - Eng MH - Abattoirs MH - Animal MH - Brucellosis, Bovine/*epidemiology MH - Cattle MH - Cattle Diseases/*epidemiology MH - Leptospirosis/*epidemiology MH - Philippines PT - JOURNAL ARTICLE DA - 671221 DP - 1967 Apr-Jun IS - 0001-6071 TA - Acta Med Philipp PG - 275-6 CY - PHILIPPINES IP - 4 VI - 3 JC - 138 EM - 6801 PMID- 6069636 CU - 88 SO - Acta Med Philipp 1967 Apr-Jun;3(4):275-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67221161 AU - Michna SW TI - Animal leptospirosis in the British Isles. A serological survey. LA - Eng MH - Agglutination Tests MH - Animal MH - *Artiodactyla MH - Cattle MH - Cattle Diseases/*epidemiology MH - Dog Diseases/*epidemiology MH - Dogs MH - Great Britain MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/epidemiology/*veterinary MH - Sheep MH - Sheep Diseases/*epidemiology MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 671022 DP - 1967 Apr 1 IS - 0042-4900 TA - Vet Rec PG - 394-401 SB - M CY - ENGLAND IP - 13 VI - 80 JC - XBS EM - 6711 PMID- 6068387 CU - 88 SO - Vet Rec 1967 Apr 1;80(13):394-401 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67209212 AU - Doherty PC AU - Baynes ID TI - The effect of feeding oxytetracycline on leptospiruria in pigs infected with Leptospira pomana. LA - Eng MH - Agglutination Tests MH - Animal MH - Leptospirosis/drug therapy/urine/*veterinary MH - Oxytetracycline/*therapeutic use MH - Swine MH - Swine Diseases/*drug therapy PT - JOURNAL ARTICLE DA - 671012 DP - 1967 Apr IS - 0005-0423 TA - Aust Vet J PG - 135-7 SB - M CY - AUSTRALIA IP - 4 VI - 43 JC - 9IE EM - 6711 PMID- 6067999 CU - 85 SO - Aust Vet J 1967 Apr;43(4):135-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67211740 AU - Solorzano RF TI - A comparison of the rapid macroscopic slide agglutination test with the microscopic agglutination test for leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Dogs MH - Horses MH - Leptospirosis/*diagnosis/immunology/*veterinary MH - Swine PT - JOURNAL ARTICLE DA - 671014 DP - 1967 Apr IS - 0010-8901 TA - Cornell Vet PG - 239-49 SB - M CY - UNITED STATES IP - 2 VI - 57 JC - DRI EM - 6711 PMID- 6035200 SO - Cornell Vet 1967 Apr;57(2):239-49 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 67209213 AU - Doherty PC TI - Streptomycin treatment of bovine carriers of Leptospira pomona. LA - Eng MH - Agglutination Tests MH - Animal MH - Carrier State/*veterinary MH - Cattle MH - Cattle Diseases/*drug therapy MH - Injections, Intramuscular/veterinary MH - Leptospirosis/*drug therapy/urine MH - Streptomycin/*therapeutic use PT - JOURNAL ARTICLE DA - 671012 DP - 1967 Apr IS - 0005-0423 TA - Aust Vet J PG - 138-9 SB - M CY - AUSTRALIA IP - 4 VI - 43 JC - 9IE EM - 6711 PMID- 6033736 SO - Aust Vet J 1967 Apr;43(4):138-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67126665 AU - Friedlaender P AU - Osler M TI - Icterus and pregnancy. LA - Eng MH - Cholelithiasis/complications MH - Female MH - Hepatitis A/complications MH - Hepatitis, Toxic/complications MH - Human MH - Hyperbilirubinemia, Hereditary/complications MH - Hyperemesis Gravidarum/complications MH - *Infant Mortality MH - Infant, Newborn MH - *Infant, Premature MH - Jaundice/*complications MH - Jaundice, Chronic Idiopathic/complications MH - Leptospirosis/complications MH - Liver Cirrhosis/complications MH - Liver Diseases/complications MH - Pregnancy MH - *Pregnancy Complications, Infectious MH - Pregnancy Toxemias/complications MH - Steroids PT - JOURNAL ARTICLE DA - 670526 DP - 1967 Apr 1 IS - 0002-9378 TA - Am J Obstet Gynecol PG - 894-900 SB - A SB - M CY - UNITED STATES IP - 7 VI - 97 JC - 3NI EM - 6707 PMID- 6021104 CU - 96 SO - Am J Obstet Gynecol 1967 Apr 1;97(7):894-900 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [209 medline neighbors] UI - 71133719 AU - Guimaraes SJ AU - Raucci Neto J AU - Vieira ME TI - [Leptospirosis. General considerations. Report of 2 cases] LA - Por MH - Adult MH - English Abstract MH - Human MH - *Leptospirosis MH - Male PT - JOURNAL ARTICLE DA - 710425 DP - 1967 Apr-Jun TA - Arq Bras Med PG - 128-38 CY - BRAZIL IP - 2 VI - 54 JC - 8QU EM - 7106 PMID- 5633680 CU - 89 TT - Leptospirose. Consideracoes gerais. Apresentacao de 2 casos. SO - Arq Bras Med 1967 Apr-Jun;54(2):128-38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69200865 AU - Gazarian VS TI - [A leptospirosis antigen for the complement fixation test] LA - Rus MH - Animal MH - *Antigens MH - *Complement Fixation Tests MH - Leptospirosis/*diagnosis/*veterinary PT - JOURNAL ARTICLE DA - 690724 DP - 1967 Apr IS - 0042-4846 TA - Veterinariia PG - 102-3 CY - USSR IP - 4 VI - 44 JC - XCC EM - 6909 PMID- 5629488 CU - 85 TT - Leptospiroznyi antigen dlia reaktsii sviazyvaniia komplementa. SO - Veterinariia 1967 Apr;44(4):102-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69084372 AU - De Sande AG AU - Pumarola A TI - [Leptospirosis in the rice fields in Spain (national epidemiological survey 1964-1965)] LA - Spa MH - Human MH - Leptospirosis/*epidemiology MH - *Rice MH - Spain PT - JOURNAL ARTICLE DA - 690225 DP - 1967 Apr-Jun IS - 0034-8899 TA - Rev Sanid Hig Publica (Madr) PG - 119-33 CY - SPAIN IP - 4 VI - 41 JC - T41 EM - 6904 PMID- 5604483 CU - 88 TT - La leptosp rosis de ls arrozales en Espana. (Eneuesta epidemiologica nacional "19641965") SO - Rev Sanid Hig Publica (Madr) 1967 Apr-Jun;41(4):119-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 69200866 AU - Sivash NE TI - [A method of purifying leptospira cultures of extraneous microflora] LA - Rus MH - *Bacteriological Techniques MH - Leptospira/*isolation & purification MH - *Veterinary Medicine PT - JOURNAL ARTICLE DA - 690724 DP - 1967 Apr IS - 0042-4846 TA - Veterinariia PG - 103-4 CY - USSR IP - 4 VI - 44 JC - XCC EM - 6909 PMID- 4890957 CU - 90 TT - Sposob ochistki kul'tur leptospir ot postoronnei mikroflory. SO - Veterinariia 1967 Apr;44(4):103-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69200881 AU - Dubakin NI AU - Vishniakov IF AU - Etleshev GS AU - Varlamov IS TI - [On the epizootiology of leptospirosis in animals] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/*veterinary MH - Rats MH - Russia MH - Sheep MH - Sheep Diseases/*epidemiology MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 690724 DP - 1967 Apr IS - 0042-4846 TA - Veterinariia PG - 35-8 CY - USSR IP - 4 VI - 44 JC - XCC EM - 6909 PMID- 4239290 CU - 92 TT - K epizootologii leptospiroza zhivotnykh. SO - Veterinariia 1967 Apr;44(4):35-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68360185 AU - Kemenes F TI - [Leptospirosis of the swine] LA - Ger MH - Abortion/*microbiology MH - Animal MH - Blood Protein Electrophoresis MH - Female MH - Leptospira/classification MH - Leptospirosis/*veterinary MH - Pregnancy MH - Pregnancy Complications/*veterinary MH - Pregnancy, Animal MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 680928 DP - 1967 Mar 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 224-33 CY - GERMANY, EAST IP - 6 VI - 22 JC - NGV EM - 6811 PMID- 5627918 CU - 85 TT - Die Leptospirose des Schweines. SO - Monatsh Veterinarmed 1967 Mar 15;22(6):224-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 69010645 AU - Gsell O TI - [Therapy of leptospirosis] LA - Ita MH - Adult MH - Female MH - Human MH - Leptospirosis/*drug therapy MH - Male MH - Oxytetracycline/*administration & dosage MH - Penicillins/*administration & dosage MH - Streptomycin/*administration & dosage MH - Tetracycline/*administration & dosage PT - JOURNAL ARTICLE DA - 681205 DP - 1967 Mar 15 IS - 0009-9074 TA - Clin Ter PG - 409-15 CY - ITALY IP - 5 VI - 40 JC - DKN EM - 6901 PMID- 5601185 TT - Terapia delle leptospirosi. SO - Clin Ter 1967 Mar 15;40(5):409-15 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67261949 AU - Munnich D AU - Lakatos M TI - [Current data on the leptospirosis infection across the Tisza river] LA - Hun MH - Adolescence MH - Adult MH - Animal MH - Disease Outbreaks MH - Disease Reservoirs MH - Human MH - Hungary MH - Leptospirosis/epidemiology/immunology MH - Occupational Diseases MH - Weil's Disease/epidemiology/immunology MH - Zoonoses PT - JOURNAL ARTICLE DA - 671119 DP - 1967 Mar 5 IS - 0030-6002 TA - Orv Hetil PG - 459-63 CY - HUNGARY IP - 10 VI - 108 JC - OL8 EM - 6712 PMID- 6068997 CU - 88 TT - Ujabb adatok a "tiszantuli leptospirosis"-hoz. SO - Orv Hetil 1967 Mar 5;108(10):459-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67210647 AU - Wolff JW AU - Bohlander HJ TI - Screening tests in human serum samples with Leptospira biflexa antigens incorporated in Galton's macroscopic slide test. LA - Eng MH - Agglutination Tests MH - *Antigens MH - Human MH - Leptospira/*immunology MH - Leptospirosis/*diagnosis/immunology MH - Serodiagnosis MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE DA - 671012 DP - 1967 Mar IS - 0041-3232 TA - Trop Geogr Med PG - 63-9 SB - M CY - NETHERLANDS IP - 1 VI - 19 JC - WGJ EM - 6711 PMID- 6034623 SO - Trop Geogr Med 1967 Mar;19(1):63-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67209091 AU - Imbabi SE AU - Sleight SD AU - Conner GH AU - Schmidt DA TI - Experimental leptospirosis: Leptospira canicola infection in calves. LA - Eng MH - Agglutination Tests MH - Animal MH - Antibody Formation MH - Body Temperature MH - Cattle MH - *Cattle Diseases/diagnosis/pathology MH - Leptospira canicola/isolation & purification MH - Leptospirosis/diagnosis/pathology/veterinary PT - JOURNAL ARTICLE DA - 671012 DP - 1967 Mar IS - 0002-9645 TA - Am J Vet Res PG - 413-9 SB - M CY - UNITED STATES IP - 123 VI - 28 JC - 40C EM - 6711 PMID- 6033694 SO - Am J Vet Res 1967 Mar;28(123):413-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 69238828 AU - Moteiunas LI AU - Urbelene IaA TI - [Distribution of leptospirosis infection among epidemiologically threatened contingents of the towns and villages of Lithuanian SSR] LA - Rus MH - Animal MH - Human MH - Leptospirosis/*epidemiology MH - Lithuania MH - Occupational Diseases/*epidemiology MH - Rodent Diseases/epidemiology PT - JOURNAL ARTICLE DA - 690904 DP - 1967 Mar IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 129-33 SB - M CY - USSR IP - 3 VI - 44 JC - Y9O EM - 6910 RO - M:CNR PMID- 5795712 LR - 880520 CU - 88 TT - Rasprostranennost' leptospiroznoi infektsii sredi epidemiologicheski ugrozhaemykh kontingentov goroda i sela Litovskoi SSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Mar;44(3):129-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69238821 AU - Godlevskaia MV AU - Drankin DI AU - Rumiantseva EV TI - [Leptospirosis among workers at the Engels meat-packing plant] LA - Rus MH - Agglutination Tests MH - English Abstract MH - Human MH - Leptospira canicola MH - Leptospira interrogans MH - Leptospirosis/diagnosis/*epidemiology/immunology MH - *Meat-Packing Industry MH - Occupational Diseases/diagnosis/*epidemiology/immunology PT - JOURNAL ARTICLE DA - 690904 DP - 1967 Mar IS - 0372-9311 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 114-7 SB - M CY - USSR IP - 3 VI - 44 JC - Y9O EM - 6910 RO - M:CNR PMID- 5795710 LR - 880520 CU - 88 TT - Leptospiroz sredi rabochikh engel'sskogo miasokombinata. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Mar;44(3):114-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 69268519 AU - Bukhovets' VD TI - [On morphological variability of leptospires] LA - Ukr MH - English Abstract MH - Leptospira/*cytology PT - JOURNAL ARTICLE DA - 691007 DP - 1967 Mar-Apr IS - 0026-3664 TA - Mikrobiol Zh PG - 121-5 CY - USSR IP - 2 VI - 29 JC - MZ2 EM - 6911 PMID- 5618075 TT - Do pytannia pro morfolohichun minlyvist' leptospir. SO - Mikrobiol Zh 1967 Mar-Apr;29(2):121-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 70040521 AU - Geimos EK TI - [The current concept of the etiology of uveitis in persons of various ages (a review of the foreign literature)] LA - Rus MH - Adolescence MH - Adult MH - Age Factors MH - Brucellosis/complications MH - Child MH - Child, Preschool MH - Histoplasmosis/complications MH - Human MH - Infection/complications MH - Leptospirosis/complications MH - Ophthalmia, Sympathetic/complications MH - Rheumatic Fever/complications MH - Sarcoidosis/complications MH - Syphilis/complications MH - Toxoplasmosis/complications MH - Tuberculosis/complications MH - Uveitis/*etiology PT - JOURNAL ARTICLE PT - REVIEW DA - 700109 DP - 1967 Mar-Apr IS - 0042-465X TA - Vestn Oftalmol PG - 81-5 CY - USSR IP - 2 VI - 80 JC - XAO EM - 7002 RF - 32 PMID- 4901205 CU - 90 TT - Sovremennye predstavleniia ob etiologii uveitov u lits razlichnogo vozrasta (obzor inostrannoi literatury) SO - Vestn Oftalmol 1967 Mar-Apr;80(2):81-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [124 medline neighbors] UI - 68328535 AU - Parnas J AU - Poplawski S AU - Cybulska M TI - Investigations on serotypes of Leptospirae by infrared spectrophotometry. LA - Eng MH - Antigens MH - *Infrared Rays MH - Leptospira/classification/*immunology MH - Methods MH - *Spectrophotometry PT - JOURNAL ARTICLE DA - 680906 DP - 1967 Mar IS - 0044-2879 TA - Z Immunitatsforsch Allerg Klin Immunol PG - 218-24 SB - M CY - GERMANY, WEST IP - 3 VI - 132 JC - BFI EM - 6810 PMID- 4232735 CU - 92 SO - Z Immunitatsforsch Allerg Klin Immunol 1967 Mar;132(3):218-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 67248995 AU - Plesko I AU - Hruzik J AU - Sasvari K TI - [First experience with a polyvalent antileptospiral vaccine under our conditions] LA - Slo MH - Adult MH - Czechoslovakia MH - Human MH - Leptospirosis/*prevention & control MH - Occupational Diseases/*prevention & control MH - Vaccines/*therapeutic use PT - JOURNAL ARTICLE DA - 671111 DP - 1967 Feb 28 IS - 0006-9248 TA - Bratisl Lek Listy PG - 209-18 CY - CZECHOSLOVAKIA IP - 4 VI - 47 JC - B5N EM - 6712 PMID- 6040726 TT - Prve skusenosti s polyvalentnou vakcinou proti leptospirozam v nasich podmienkach. SO - Bratisl Lek Listy 1967 Feb 28;47(4):209-18 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67248994 AU - Bazovska S AU - Kmety E TI - [Contribution to the problem of leptospire transmission] LA - Slo MH - Animal MH - Guinea Pigs MH - Leptospira/*pathogenicity MH - Leptospirosis/*epidemiology MH - Virulence/physiology PT - JOURNAL ARTICLE DA - 671111 DP - 1967 Feb 28 IS - 0006-9248 TA - Bratisl Lek Listy PG - 205-8 CY - CZECHOSLOVAKIA IP - 4 VI - 47 JC - B5N EM - 6712 PMID- 6040725 CU - 88 TT - Prispevok k otazke transformacie leptospir. SO - Bratisl Lek Listy 1967 Feb 28;47(4):205-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68359347 AU - Horsch F TI - [Leptospira hyos infections of pigs in the German Democratic Republic] LA - Ger MH - Abortion, Veterinary/*etiology MH - Animal MH - Female MH - Germany, East MH - Leptospira/*isolation & purification MH - Leptospirosis/blood/epidemiology/*veterinary MH - Pregnancy MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 680928 DP - 1967 Feb 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 144-7 CY - GERMANY, EAST IP - 4 VI - 22 JC - NGV EM - 6811 PMID- 5627858 CU - 88 TT - Leptospira-hyos-Infektionen bei Schweinen in der DDR. SO - Monatsh Veterinarmed 1967 Feb 15;22(4):144-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68359346 AU - Senf W TI - [Contribution to the leptospirotic abortion in pigs] LA - Ger MH - Abortion, Veterinary/*etiology MH - Animal MH - Female MH - Fetus/*pathology MH - Kidney/pathology MH - Leptospira/*isolation & purification MH - Leptospirosis/complications/*veterinary MH - Pregnancy MH - Pregnancy, Animal MH - Swine MH - Swine Diseases/*complications MH - Zoonoses PT - JOURNAL ARTICLE DA - 680928 DP - 1967 Feb 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 135-44 CY - GERMANY, EAST IP - 4 VI - 22 JC - NGV EM - 6811 PMID- 5627857 CU - 85 TT - Beitrag zum Leptospirenabort beim Schwein. SO - Monatsh Veterinarmed 1967 Feb 15;22(4):135-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67222646 AU - Fry DR TI - Leptospirosis in West Cameroon. LA - Eng MH - Adult MH - Cameroon MH - Fever/etiology MH - Human MH - *Leptospirosis MH - Male PT - JOURNAL ARTICLE DA - 671022 DP - 1967 Feb IS - 0266-6502 TA - West Afr Med J Niger Pract PG - 44-5 CY - ENGLAND IP - 1 VI - 16 JC - WAN EM - 6711 RO - M:BDS PMID- 6039018 LR - 860707 SO - West Afr Med J Niger Pract 1967 Feb;16(1):44-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [84 medline neighbors] UI - 67122177 AU - Johnson RC AU - Harris VG TI - Antileptospiral activity of serum. II. Leptospiral virulence factor. LA - Eng MH - Animal MH - *Antibodies MH - Azaguanine/pharmacology MH - *Blood MH - Blood Bactericidal Activity MH - *Complement MH - Guinea Pigs MH - Hamsters MH - Hemagglutination Tests MH - Immunity MH - Leptospira/*drug effects/pathogenicity MH - Rabbits MH - Virulence/*drug effects PT - JOURNAL ARTICLE DA - 670512 DP - 1967 Feb IS - 0021-9193 TA - J Bacteriol PG - 513-9 SB - M CY - UNITED STATES IP - 2 VI - 93 JC - HH3 EM - 6707 PMID- 6020558 SO - J Bacteriol 1967 Feb;93(2):513-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68094346 AU - Bevan-Jones H AU - Miller DL TI - Bacterial meningitis, 1962-63. LA - Eng MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Child MH - Child, Preschool MH - Female MH - Great Britain MH - Human MH - Infant MH - Infant, Newborn MH - Leptospirosis/epidemiology MH - Male MH - Meningitis/*epidemiology MH - Meningitis, Haemophilus/epidemiology MH - Meningitis, Listeria/epidemiology MH - Meningitis, Meningococcal/epidemiology MH - Meningitis, Pneumococcal/epidemiology MH - Middle Age MH - Mycoses/epidemiology MH - Occupations MH - Sex Factors MH - Tuberculosis, Meningeal/epidemiology PT - JOURNAL ARTICLE DA - 680215 DP - 1967 Feb TA - Mon Bull Minist Health Public Health Lab Serv PG - 22-30 CY - ENGLAND VI - 26 JC - NGT EM - 6803 PMID- 5630454 CU - 89 SO - Mon Bull Minist Health Public Health Lab Serv 1967 Feb;26:22-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 68412841 AU - Burger G AU - Fuchs GH TI - [Lag phase and exponential growth phase in leptospiras as functions of inoculation size] LA - Ger MH - Bacteriological Techniques MH - Culture Media MH - Leptospira/*growth & development MH - Leptospira interrogans/growth & development MH - Temperature PT - JOURNAL ARTICLE DA - 681106 DP - 1967 Feb TA - Zentralbl Bakteriol [Orig] PG - 388-94 SB - M CY - GERMANY, WEST IP - 3 VI - 202 JC - Y4Y EM - 6812 PMID- 4878033 CU - 90 TT - Verzogerungsphase und exponentielle Vermehrungsrate bei Leptospiren als Funktionen der Einsaatgrosse. SO - Zentralbl Bakteriol [Orig] 1967 Feb;202(3):388-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 69061482 AU - Tagi-Zade TA AU - Alekperov FP TI - [Water fowl as a possible source of leptospirosis infection] LA - Rus MH - Animal MH - Azerbaijan MH - *Birds MH - *Disease Reservoirs MH - Human MH - Leptospirosis/*etiology MH - *Zoonoses PT - JOURNAL ARTICLE DA - 690204 DP - 1967 Feb TA - Zh Mikrobiol Epidemiol Immunobiol PG - 140-3 SB - M CY - USSR IP - 2 VI - 44 JC - Y9O EM - 6903 PMID- 4235750 CU - 92 TT - Vodoplavaiushchie ptitsy kak vozmozhnyi istochnik leptospiroznoi infedtsii. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Feb;44(2):140-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 68328384 AU - De Brito T AU - Machado MM AU - Montans SD AU - Hoshino S AU - Freymuller E TI - Liver biopsy in human leptospirosis: a light and electron microscopy study. LA - Eng MH - Acid Phosphatase/analysis MH - Alkaline Phosphatase/analysis MH - Biopsy MH - Cytochrome-c Oxidase/analysis MH - Esterases/analysis MH - Histological Techniques MH - Human MH - Leptospirosis/enzymology/*pathology MH - Liver/enzymology/*pathology MH - Microscopy, Electron MH - Succinate Dehydrogenase/analysis PT - JOURNAL ARTICLE DA - 680906 DP - 1967 Jan 11 TA - Virchows Arch Pathol Anat Physiol Klin Med PG - 61-9 CY - GERMANY, WEST IP - 1 VI - 342 JC - XDG EM - 6810 PMID- 4298629 CU - 93 SO - Virchows Arch Pathol Anat Physiol Klin Med 1967 Jan 11;342(1):61-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68098948 AU - Kemenes F AU - Temesvari E TI - A new leptospiral serotype in albino rat breeds. LA - Eng MH - Agglutination Tests MH - Animal MH - Kidney/immunology MH - Leptospirosis/*immunology/*veterinary MH - Rats MH - Rodent Diseases/*immunology PT - JOURNAL ARTICLE DA - 680226 DP - 1967 IS - 0001-7205 TA - Acta Vet Acad Sci Hung PG - 257-61 CY - HUNGARY IP - 3 VI - 17 JC - 27P EM - 6804 PMID- 6076540 SO - Acta Vet Acad Sci Hung 1967;17(3):257-61 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67257673 AU - Nasikowska M TI - [Results of serologic tests for leptospira in the serum of animals in selected territories] LA - Pol MH - Agglutination Tests MH - Animal MH - Cattle MH - Horse Diseases/immunology MH - Horses MH - Leptospirosis/*veterinary MH - Poland MH - Rodent Diseases/immunology MH - Sheep MH - Sheep Diseases/immunology PT - JOURNAL ARTICLE DA - 671118 DP - 1967 IS - 0033-2100 TA - Przegl Epidemiol PG - 59-65 CY - POLAND IP - 1 VI - 21 JC - Q8T EM - 6712 PMID- 6068849 CU - 85 TT - Wyniki badan serologicznych w kierunku leptospir surowic zwierzat na wybranych terenach. SO - Przegl Epidemiol 1967;21(1):59-65 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68082371 AU - Migdalska-Kassurowa B TI - [Pattern of morphologic content of peripheral blood and erythrocyte sedimentation in leptospiroses] LA - Pol MH - Adolescence MH - Adult MH - Blood Cell Count MH - Blood Coagulation Tests MH - *Blood Sedimentation MH - Child MH - Female MH - Hemoglobins/*analysis MH - Human MH - Leptospirosis/*blood MH - Leukocytosis MH - Leukopenia MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 680128 DP - 1967 IS - 0032-3772 TA - Pol Arch Med Wewn PG - 325-33 CY - POLAND IP - 3 VI - 39 JC - PAV EM - 6803 PMID- 6063333 TT - Zachowanie sie skladu morfologicznego krwi obwodowej i opadania krwinek w leptospirozach. SO - Pol Arch Med Wewn 1967;39(3):325-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68080127 AU - Chorvath B TI - Gel filtration of leptospiral lipase on sephadex g 200. LA - Eng MH - Chromatography, Gel MH - Dextrans MH - Leptospira/*enzymology MH - *Lipase PT - JOURNAL ARTICLE DA - 680127 DP - 1967 IS - 0006-3088 TA - Biologia (Bratisl) PG - 817-22 CY - CZECHOSLOVAKIA IP - 11 VI - 22 JC - A4G EM - 6803 PMID- 6062275 SO - Biologia (Bratisl) 1967;22(11):817-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67262358 AU - Plesko I AU - Vladar M TI - An attempt at an objective evaluation of the oxidase reaction in leptospira cultures. LA - Eng MH - Colorimetry MH - Leptospira/*metabolism MH - Oxidoreductases/*metabolism PT - JOURNAL ARTICLE DA - 671120 DP - 1967 IS - 0006-3088 TA - Biologia (Bratisl) PG - 90-5 CY - CZECHOSLOVAKIA IP - 2 VI - 22 JC - A4G EM - 6712 PMID- 6047258 SO - Biologia (Bratisl) 1967;22(2):90-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67257672 AU - Migdalska-Kassurowa B AU - Dymowska Z TI - [Pattern of the agglutination-lysis test in 75 cases of various spirochytoses] LA - Pol MH - Agglutination Tests MH - Antibiotics/*therapeutic use MH - Human MH - Leptospira/drug effects MH - Leptospira canicola/drug effects MH - Leptospirosis/*diagnosis MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 671118 DP - 1967 IS - 0033-2100 TA - Przegl Epidemiol PG - 53-8 CY - POLAND IP - 1 VI - 21 JC - Q8T EM - 6712 PMID- 6044683 TT - Zachowanie sie odczynu aglutynachjno-litycznego w 75 przypadkach roznych kretkowic. SO - Przegl Epidemiol 1967;21(1):53-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67204814 AU - Mailloux M TI - [Use of the Leptospira biflexa Patoc antigen in the serodiagnosis of leptospirosis] LA - Fre MH - *Antigens MH - Human MH - *Leptospira MH - Leptospirosis/*diagnosis MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 671002 DP - 1967 Jan IS - 0020-2444 TA - Ann Inst Pasteur (Paris) PG - 121-5 SB - M CY - FRANCE IP - 1 VI - 112 JC - 58Y EM - 6711 PMID- 6031422 TT - Utilite de l'antigene Leptospira biflexa Patoc dans les serodiagnostics de leptospiroses. SO - Ann Inst Pasteur (Paris) 1967 Jan;112(1):121-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [100 medline neighbors] UI - 67087454 AU - Tabel H AU - Karstad L TI - The renal carrier state of experimenal Leptospira pomona infections in skunks (Mephitis mephitis). LA - Eng MH - Animal MH - Animal Diseases MH - Body Temperature MH - Body Weight MH - Carnivora MH - *Disease Reservoirs MH - Kidney/*microbiology/*pathology MH - Leptospirosis/*blood/*immunology/*urine MH - Proteinuria PT - JOURNAL ARTICLE DA - 670331 DP - 1967 Jan IS - 0002-9262 TA - Am J Epidemiol PG - 9-16 SB - M CY - UNITED STATES IP - 1 VI - 85 JC - 3H3 EM - 6705 PMID- 6017273 SO - Am J Epidemiol 1967 Jan;85(1):9-16 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 67057130 AU - Schar M AU - Wiesmann E TI - [Inflammatory diseases of the meninges. Epidemiology and examination methods] LA - Ger MH - Diagnosis, Differential MH - Echoviruses MH - Human MH - Leptospirosis/diagnosis MH - Meningitis/*cerebrospinal fluid/*diagnosis/*epidemiology/*etiology MH - Meningitis, Listeria/diagnosis MH - Poliomyelitis/diagnosis MH - Switzerland PT - JOURNAL ARTICLE DA - 670304 DP - 1967 IS - 0300-1121 TA - Bibl Tuberc PG - 1-11 SB - M CY - SWITZERLAND VI - 23 JC - 9XC EM - 6704 RO - M:CNR PMID- 6015733 LR - 941219 CU - 88 TT - Die entzundlichen Erkrankungen der Meningen. Epidemiologie und Untersuchungsmethoden. SO - Bibl Tuberc 1967;23:1-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69291444 AU - Semenova LP AU - Soloshenko IZ TI - Variability of the serological properties of leptospirae within a single serotype and subserotype and its significance for the classification of leptospirae. LA - Eng MH - Adsorption MH - Animal MH - Antibodies/analysis MH - Guinea Pigs MH - Kidney/microbiology MH - Leptospira/*classification/immunology/isolation & purification MH - Serotyping MH - Swine MH - USSR PT - JOURNAL ARTICLE DA - 691031 DP - 1967 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 328-33 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 11 JC - IEV EM - 6912 PMID- 5629950 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1967;11(3):328-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69288612 AU - Kiktenko VS AU - Troshin KA TI - On the question of the morphology of leptospirae. LA - Eng MH - Cytoplasm MH - Leptospira/*cytology MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 691027 DP - 1967 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 478-82 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 11 JC - IEV EM - 6912 PMID- 5629910 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1967;11(4):478-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68126437 AU - Turner LH TI - Leptospirosis. I. LA - Eng MH - Animal MH - Animal Diseases MH - Carrier State MH - Diagnosis, Differential MH - Disease Reservoirs MH - Disease Vectors MH - Human MH - International Cooperation MH - Leptospira/classification MH - *Leptospirosis/diagnosis/etiology/prevention & control/therapy MH - Nomenclature MH - Public Health MH - Vaccination MH - Virulence MH - Zoonoses PT - JOURNAL ARTICLE DA - 680404 DP - 1967 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 842-55 SB - M CY - ENGLAND IP - 6 VI - 61 JC - WBU EM - 6805 PMID- 5625167 CU - 85 SO - Trans R Soc Trop Med Hyg 1967;61(6):842-55 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 69238848 AU - Tarasevich NN AU - Shakhanina IL AU - Mitrofanov VT TI - [The results of testing a dry complex diagnosticum in a focus of leptospiral infection] LA - Rus MH - *Agglutination Tests MH - Comparative Study MH - *Complement Fixation Tests MH - English Abstract MH - Human MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 690904 DP - 1967 IS - 0049-8726 TA - Zh Mikrobiol Epidemiol Immunobiol PG - 40-3 SB - M CY - USSR IP - 3 VI - 44 JC - Y9O EM - 6910 RO - M:MYA PMID- 5616805 LR - 820901 TT - Rezul'taty ispytaniia sukhogo kompleksnogo diagnostikuma v ochage leptospiroznoi infektsii. SO - Zh Mikrobiol Epidemiol Immunobiol 1967;44(3):40-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69131387 AU - Misenzhnikov AV TI - [The differential diagnosis of the meningeal form of tick-borne encephalitis and nonicteric leptospirosis in children] LA - Rus MH - Adolescence MH - Adult MH - Child MH - Child, Preschool MH - Diagnosis, Differential MH - Encephalitis, Tick-Borne/*diagnosis MH - Human MH - Leptospirosis/*diagnosis MH - Meningoencephalitis/*diagnosis PT - JOURNAL ARTICLE DA - 690424 DP - 1967 Jan IS - 0031-403X TA - Pediatriia PG - 61-4 CY - USSR IP - 1 VI - 46 JC - OYL EM - 6906 PMID- 5609668 TT - O differentsial'nom diagnoze meningeal'noi formy kleshchevogo entsefalita i bezzheltushnogo leptospiroza u detei. SO - Pediatriia 1967 Jan;46(1):61-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68409627 AU - Dimic E AU - Mudric V AU - Dosen H TI - [Meningitis leptospirosa] LA - Scc MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Leptospirosis/*microbiology MH - Male MH - Meningitis/*microbiology MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 681103 DP - 1967 IS - 0025-8105 TA - Med Pregl PG - 157-60 CY - YUGOSLAVIA IP - 3 VI - 20 JC - M8U EM - 6812 PMID- 5599380 TT - Meningitis leptospirosa. SO - Med Pregl 1967;20(3):157-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [134 medline neighbors] UI - 68404249 AU - Burger G AU - Fuchs GH TI - [Effects of Zn2+ on the generation time of nephelometrically observed Leptospira populations] LA - Ger MH - Acetates/pharmacology MH - Chlorides/pharmacology MH - Culture Media MH - Leptospira/drug effects/*growth & development MH - Nitrates/pharmacology MH - Sulfates/pharmacology MH - Zinc/*pharmacology PT - JOURNAL ARTICLE DA - 681028 DP - 1967 Jan TA - Zentralbl Bakteriol [Orig] PG - 73-87 SB - M CY - GERMANY, WEST IP - 1 VI - 202 JC - Y4Y EM - 6812 PMID- 5598873 CU - 89 TT - Zn2+-Einwirkung auf die Generationsdauer nephelometrisch beobachteter Leptospirenpopulationen. SO - Zentralbl Bakteriol [Orig] 1967 Jan;202(1):73-87 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68368313 AU - Konopka EA AU - Goble FC AU - Lewis L AU - Werner L TI - Chemotherapeutic activity of certain isoquinoline compounds in experimental leptospirosis. LA - Eng MH - Animal MH - Hamsters MH - Leptospirosis/*drug therapy MH - Quinolines/chemical synthesis/*therapeutic use PT - JOURNAL ARTICLE DA - 681007 DP - 1967 IS - 0066-4804 TA - Antimicrob Agents Chemother PG - 534-6 CY - UNITED STATES VI - 7 JC - 6HK EM - 6811 PMID- 5596186 SO - Antimicrob Agents Chemother 1967;7:534-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68368312 AU - Goble FC AU - Konopka EA AU - Zoganas HC TI - Chemotherapeutic activity of certain organic selenium compounds in experimental leptospirosis. LA - Eng MH - Animal MH - Hamsters MH - Leptospirosis/*drug therapy MH - Selenium/*administration & dosage PT - JOURNAL ARTICLE DA - 681007 DP - 1967 IS - 0066-4804 TA - Antimicrob Agents Chemother PG - 531-3 CY - UNITED STATES VI - 7 JC - 6HK EM - 6811 PMID- 5596185 SO - Antimicrob Agents Chemother 1967;7:531-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [85 medline neighbors] UI - 68313901 AU - Paul W AU - Vick HP TI - [Results of serologic studies in endogenous eye inflammations] LA - Ger MH - Adolescence MH - Adult MH - Aged MH - Antistreptolysin/diagnostic use MH - Child MH - Chorioretinitis/*etiology MH - Diagnosis, Differential MH - Eye Diseases/etiology MH - Female MH - Human MH - Leptospirosis/complications/diagnosis MH - Male MH - Middle Age MH - Phlebitis/*etiology MH - *Retina MH - Serodiagnosis MH - Streptococcal Infections/complications/diagnosis MH - Syphilis/complications/diagnosis MH - Syphilis Serodiagnosis MH - Toxoplasmosis/complications/diagnosis MH - Uveitis/*etiology PT - JOURNAL ARTICLE DA - 680816 DP - 1967 IS - 0023-2165 TA - Klin Monatsbl Augenheilkd PG - 332-44 SB - M CY - GERMANY, WEST IP - 3 VI - 151 JC - KWA EM - 6810 PMID- 5590158 CU - 96 TT - Ergebnisse serologischer Untersuchungen bei endogenen Augenentzundungen. SO - Klin Monatsbl Augenheilkd 1967;151(3):332-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 68165548 AU - Lachmajer J TI - [Medical acaroentomology in Poland in 1945-1966] LA - Pol MH - *Arthropod Vectors MH - *Arthropods MH - Brucellosis MH - Human MH - *Insect Control MH - Insecticide Resistance MH - Leptospirosis MH - Poland MH - Tularemia PT - JOURNAL ARTICLE DA - 680509 DP - 1967 IS - 0043-5163 TA - Wiad Parazytol PG - 345-59 CY - POLAND IP - 4 VI - 13 JC - XOF EM - 6806 PMID- 5583395 TT - Akaroentomologia lekarska w Polsce od 1945 do 1966. SO - Wiad Parazytol 1967;13(4):345-59 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 68157303 AU - Fennestad KL AU - Olsen TS AU - Borg-Petersen C TI - Haemorrhagic nephritis in experimental bovine leptospirosis bratislava. LA - Eng MH - Agglutination Tests MH - Animal MH - Anuria/etiology MH - Cattle MH - Cattle Diseases/*microbiology MH - Hematuria/etiology MH - Hemorrhage/veterinary MH - Kidney/microbiology/*pathology MH - Leptospirosis/immunology/*pathology/veterinary MH - Nephritis/*veterinary MH - Suggestion/microbiology PT - JOURNAL ARTICLE DA - 680501 DP - 1967 TA - Acta Pathol Microbiol Scand PG - 245-64 SB - M CY - DENMARK IP - 2 VI - 71 JC - 1O0 EM - 6806 PMID- 5582846 CU - 89 SO - Acta Pathol Microbiol Scand 1967;71(2):245-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 68365373 AU - Brito T de AU - Penna DO AU - Pereira VC AU - Hoshino S TI - Kidney biopsies in human leptospirosis: a biochemical and electron microscopy study. LA - Eng MH - Acid Phosphatase/analysis MH - Adult MH - Agglutination MH - Alkaline Phosphatase/analysis MH - Bilirubin/blood MH - Biopsy MH - Histocytochemistry MH - Human MH - Kidney/enzymology/*pathology MH - Leptospirosis/enzymology/*pathology MH - Microscopy, Electron MH - Middle Age MH - Succinate Dehydrogenase/analysis PT - JOURNAL ARTICLE DA - 681005 DP - 1967 TA - Virchows Arch Pathol Anat Physiol Klin Med PG - 124-35 CY - GERMANY, WEST IP - 2 VI - 343 JC - XDG EM - 6811 PMID- 5302171 CU - 89 SO - Virchows Arch Pathol Anat Physiol Klin Med 1967;343(2):124-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 68131657 AU - Cernuha JG AU - Kokovin IL TI - The relationship between the antigenic structure of the Pomona serogroup of liptospiral serotypes and their circulation in particular species of animals in the USSR. LA - Eng MH - Adaptation, Biological MH - Animal MH - Antigen-Antibody Reactions MH - Cattle MH - Guinea Pigs MH - Human MH - Leptospira/classification/*immunology MH - Rats MH - USSR PT - JOURNAL ARTICLE DA - 680410 DP - 1967 IS - 0042-9686 TA - Bull World Health Organ PG - 335-40 CY - SWITZERLAND IP - 2 VI - 37 JC - C80 EM - 6805 PMID- 5300076 CU - 89 SO - Bull World Health Organ 1967;37(2):335-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69275921 AU - Hanson LE AU - Brodie BO TI - Leptospira hardjo infections in cattle. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*etiology MH - Female MH - Leptospirosis/etiology/*veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 691015 DP - 1967 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 210-5 CY - UNITED STATES VI - 71 JC - PY5 EM - 6912 PMID- 5257621 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1967;71:210-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69263120 AU - Lyle WE TI - Leptospirosis serology in wisconsin cattle and swine. LA - Eng MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*blood MH - Swine MH - Swine Diseases/*blood MH - Wisconsin PT - JOURNAL ARTICLE DA - 690930 DP - 1967 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 206-9 CY - UNITED STATES VI - 71 JC - PY5 EM - 6911 PMID- 5257310 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1967;71:206-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69263119 AU - Diesch SL AU - McCulloch WF AU - Crawford RP AU - Bennett PC AU - Braun JL TI - Epidemiologic studies of Leptospira grippotyphosa and Leptospira hardjo infections in Iowa cattle. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Iowa MH - Leptospira/isolation & purification MH - Leptospirosis/epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 690930 DP - 1967 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 195-205 CY - UNITED STATES VI - 71 JC - PY5 EM - 6911 PMID- 5257309 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1967;71:195-205 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [65 medline neighbors] UI - 68402343 AU - Parnas J AU - Hencner Z AU - Poplawski S AU - Pleszczynska E AU - Cybulska M TI - [Infrared spectrophotometry and immunochemical studies of Brucella Klebsiella, Listeria, Erysipelothrix and Leptospira] LA - Ger MH - Bacteria/*analysis MH - Brucella/analysis MH - Erysipelothrix/analysis MH - Immunochemistry MH - Infrared Rays MH - Klebsiella/analysis MH - Leptospira/analysis MH - Listeria monocytogenes/analysis MH - Spectrophotometry PT - JOURNAL ARTICLE DA - 681028 DP - 1967 IS - 0003-9055 TA - Arch Exp Veterinarmed PG - 867-80 SB - M CY - GERMANY, EAST IP - 4 VI - 21 JC - 70I EM - 6812 PMID- 4970715 CU - 91 TT - Infrarotspektrophotometrische und immunochemische Untersuchungen bei Brucellen, Klebsiellen, Listerien, Erysipelothrix und Leptospiren. SO - Arch Exp Veterinarmed 1967;21(4):867-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [143 medline neighbors] UI - 68316177 TI - Current problems in leptospirosis research. Report of a WHO Expert Group. LA - Eng MH - Animal MH - Animal Diseases MH - Disease Reservoirs MH - Human MH - Leptospira/classification MH - *Leptospirosis/diagnosis/immunology/therapy/veterinary MH - Research MH - World Health Organization PT - JOURNAL ARTICLE DA - 680823 DP - 1967 TA - World Health Organ Tech Rep Ser PG - 1-32 CY - SWITZERLAND VI - 380 JC - XO5 EM - 6810 PMID- 4968935 CU - 91 NI - A SO - World Health Organ Tech Rep Ser 1967;380:1-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [152 medline neighbors] UI - 67061496 AU - Martin RJ AU - Hanson LE AU - Schnurrenberger PR TI - Leptospiral interspecies infections on an Illinois farm. LA - Eng MH - Animal MH - Cats MH - Cattle MH - Cattle Diseases/*microbiology MH - Human MH - Illinois MH - Leptospira/isolation & purification MH - Leptospirosis/*epidemiology MH - Mice MH - Rabbits MH - Rats MH - Zoonoses PT - JOURNAL ARTICLE DA - 670310 DP - 1967 Jan IS - 0094-6214 TA - Public Health Rep PG - 75-83 SB - A SB - M CY - UNITED STATES IP - 1 VI - 82 JC - PHR EM - 6704 PMID- 4959493 CU - 91 SO - Public Health Rep 1967 Jan;82(1):75-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [139 medline neighbors] UI - 69291445 AU - Cerva L TI - Korthof's solid medium and the role of specific and nonspecific inhibitors in the cultivation of leptospirae in tissues. LA - Eng MH - Animal MH - Bacteriological Techniques MH - *Culture Media MH - Guinea Pigs MH - Kidney/*microbiology MH - Kidney Tubules/microbiology MH - Leptospira/*growth & development/isolation & purification MH - Liver/*microbiology PT - JOURNAL ARTICLE DA - 691031 DP - 1967 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 334-46 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 11 JC - IEV EM - 6912 PMID- 4897781 CU - 90 SO - J Hyg Epidemiol Microbiol Immunol 1967;11(3):334-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 69288611 AU - Semenova LP AU - Soloshenko LI TI - Isolation of subserotypes of leptospirae of the Tarassovi S. Hyos group, previously unknown in the U.S.S.R. LA - Eng MH - Absorption MH - Animal MH - Bacteriological Techniques MH - Cattle MH - Leptospira/classification/*isolation & purification MH - Serotyping MH - USSR PT - JOURNAL ARTICLE DA - 691027 DP - 1967 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 472-7 SB - M CY - CZECHOSLOVAKIA IP - 4 VI - 11 JC - IEV EM - 6912 PMID- 4897549 CU - 90 SO - J Hyg Epidemiol Microbiol Immunol 1967;11(4):472-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [13 medline neighbors] UI - 69057691 AU - Karpov SP TI - [Prevention of natural focal diseases in connection with assimilation of new regions in Siberia and the Far East] LA - Rus MH - *Communicable Disease Control MH - Encephalitis/prevention & control MH - Encephalitis, Japanese/prevention & control MH - Encephalitis, Tick-Borne/prevention & control MH - Far East MH - Human MH - Insect Control MH - Leptospirosis/prevention & control MH - Siberia MH - Ticks MH - USSR PT - JOURNAL ARTICLE DA - 690130 DP - 1967 Jan TA - Zh Mikrobiol Epidemiol Immunobiol PG - 79-83 SB - M CY - USSR IP - 1 VI - 44 JC - Y9O EM - 6903 PMID- 4302123 CU - 93 TT - Profilaktika prirodnoochagovykh boleznepi v sviazi osvoeniem novykh rainov v sibiri i na dal'nem Vostoke. SO - Zh Mikrobiol Epidemiol Immunobiol 1967 Jan;44(1):79-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 69214612 AU - Chernukha IuG TI - [Technic of immuno-absorptive analysis of the antigenic structure of Leptospira] LA - Rus MH - Absorption MH - Animal MH - *Antigen-Antibody Reactions MH - Immune Sera MH - Leptospira/*immunology MH - Methods MH - Rabbits PT - JOURNAL ARTICLE DA - 690806 DP - 1967 IS - 0023-6748 TA - Lab Delo PG - 116-20 CY - USSR VI - 2 JC - KYU EM - 6909 PMID- 4182494 CU - 95 TT - Tekhnika immuno-absorbtsionnogo analiza antigennoi struktyry leptospir. SO - Lab Delo 1967;2:116-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [170 medline neighbors] UI - 69214611 AU - Kiktenko VS AU - Troshin KA TI - [Change in the morphology of Leptospira under the effect of antibiotics of the tetracycline group] LA - Rus MH - Chlortetracycline/*pharmacology MH - Leptospira/*drug effects MH - Microscopy, Electron MH - Oxytetracycline/*pharmacology MH - Tetracycline/*pharmacology PT - JOURNAL ARTICLE DA - 690806 DP - 1967 IS - 0023-6748 TA - Lab Delo PG - 114-6 CY - USSR VI - 2 JC - KYU EM - 6909 PMID- 4182493 CU - 95 TT - Izmenenie Morfologii leptospir pod vliianiem antibiotikov tetratsiklinovoi gruppy. SO - Lab Delo 1967;2:114-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [140 medline neighbors] UI - 69183269 AU - Nikiforova-Menshutina AS AU - Cherkasova VV TI - [Utilizing the passive protection test for assessing the immunogenicity of leptospiral vaccine] LA - Rus MH - Animal MH - Immunity, Maternally-Acquired MH - Leptospira/*immunology MH - Leptospirosis/*prevention & control MH - Rabbits MH - *Vaccines PT - JOURNAL ARTICLE DA - 690629 DP - 1967 IS - 0023-6748 TA - Lab Delo PG - 353-7 CY - USSR VI - 6 JC - KYU EM - 6908 PMID- 4181331 CU - 95 TT - Ispol'zovanie testa passivnoi zashchity dlia otsenki immunogennosti leptospiroznoi vaktsiny. SO - Lab Delo 1967;6:353-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67250616 AU - Willinger H TI - [Infectious abortion in Bang-negative cattle] LA - Ger MH - Abortion, Veterinary/*etiology MH - Animal MH - Cattle MH - Cattle Diseases/*etiology MH - Female MH - Leptospirosis/*veterinary MH - Pregnancy MH - Weil's Disease/*veterinary PT - JOURNAL ARTICLE DA - 671111 DP - 1966 Dec IS - 0043-535X TA - Wien Tierarztl Monatsschr PG - 824-34 CY - AUSTRIA IP - 12 VI - 53 JC - XOZ EM - 6712 PMID- 6013653 CU - 86 TT - Infektioser Abortus bei bangnegativen Rindern. SO - Wien Tierarztl Monatsschr 1966 Dec;53(12):824-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 68397417 AU - Il'inskii SA TI - [Leptospirosis in dogs. (Clinical observations)] LA - Rus MH - Animal MH - Dog Diseases/*diagnosis MH - Dogs MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 681019 DP - 1966 Dec IS - 0042-4846 TA - Veterinariia PG - 27-8 CY - USSR IP - 12 VI - 43 JC - XCC EM - 6812 PMID- 6012086 CU - 85 TT - Leptospiroz sobak. (Klinicheskie nabliudeniia) SO - Veterinariia 1966 Dec;43(12):27-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68397416 AU - Popov VI TI - [On the differential diagnosis of leptospirosis in swine] LA - Rus MH - Animal MH - Diagnosis, Differential MH - Leptospirosis/*veterinary MH - Swine MH - Swine Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 681019 DP - 1966 Dec IS - 0042-4846 TA - Veterinariia PG - 25-7 CY - USSR IP - 12 VI - 43 JC - XCC EM - 6812 PMID- 6012085 CU - 85 TT - O differentsial'noi diagnostike leptospiroza svinei. SO - Veterinariia 1966 Dec;43(12):25-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68044711 AU - Fiocre B AU - Dorolle CL TI - [Enzootic disease in young calves. Probable role of a Leptospiran type belonging to the serum group "australis"] LA - Fre MH - Animal MH - Blood Groups MH - Cattle MH - Cattle Diseases/*blood MH - Leptospira/*isolation & purification MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 680112 DP - 1966 Dec IS - 0001-4192 TA - Bull Acad Vet Fr PG - 383-90 CY - FRANCE IP - 10 VI - 39 JC - BA8 EM - 6802 PMID- 6010708 CU - 85 TT - Enzootie chez des jeunes veaux. Role probable d'un type leptospirien appartenant au serogroupe "australis". SO - Bull Acad Vet Fr 1966 Dec;39(10):383-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69220013 AU - Chernukha IuG AU - Sakhartseva TF TI - [Antigenic structure of strains of Leptospira type sorex isolated from the USSR] LA - Rus MH - Agglutination Tests MH - Antigens/*analysis MH - English Abstract MH - Leptospira/analysis/classification/*immunology MH - USSR PT - JOURNAL ARTICLE DA - 690808 DP - 1966 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 55-8 SB - M CY - USSR IP - 12 VI - 43 JC - Y9O EM - 6909 PMID- 6004634 CU - 89 TT - Antigennaia struktura shtammov Leptospir tipa sorex, vydelennykh v SSSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Dec;43(12):55-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69220008 AU - Samedov AS TI - [A method of preparing lyophilized leptospirosis antigen for the complement fixation test] LA - Rus MH - Antigens/analysis/*isolation & purification MH - *Complement Fixation Tests MH - English Abstract MH - Freeze Drying MH - Leptospira/*analysis MH - Leptospira interrogans/analysis MH - Leptospirosis/diagnosis MH - Methods MH - Ultrasonics MH - Weil's Disease/diagnosis PT - JOURNAL ARTICLE DA - 690808 DP - 1966 Dec TA - Zh Mikrobiol Epidemiol Immunobiol PG - 37-41 SB - M CY - USSR IP - 12 VI - 43 JC - Y9O EM - 6909 PMID- 6004632 CU - 90 TT - Metodika prigotovleniia liofilizirovannogo leptospiroznogo antigena dlia reaktsii sviazyvaniia komplementa. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Dec;43(12):37-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 69062982 AU - Sedov VA TI - [On the incidence of meningoencephalitis in swamp fever] LA - Rus MH - Adolescence MH - Human MH - Leptospirosis/*complications/epidemiology MH - Meningoencephalitis/cerebrospinal fluid/*etiology MH - USSR PT - JOURNAL ARTICLE DA - 690205 DP - 1966 Dec IS - 0023-2149 TA - Klin Med (Mosk) PG - 112-4 CY - USSR IP - 12 VI - 44 JC - KW2 EM - 6903 PMID- 6004334 CU - 88 TT - O chastote meningo-entsefalita pri vodnoi likhoradke. SO - Klin Med (Mosk) 1966 Dec;44(12):112-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67253991 AU - Bhamarapravati N AU - Boonyapaknavig V AU - Viranuvatti V AU - Tuchinda U AU - Boonnag D AU - Nye SW TI - Liver changes in leptospirosis. A study of needle biopsies in twenty- two cases. LA - Eng MH - Adolescence MH - Adult MH - Biopsy MH - Female MH - Human MH - Leptospirosis/diagnosis/*pathology MH - Liver/*pathology MH - Male MH - Middle Age MH - Thailand PT - JOURNAL ARTICLE DA - 671114 DP - 1966 Dec IS - 0002-9521 TA - Am J Proctol PG - 480-7 CY - UNITED STATES IP - 6 VI - 17 JC - 3UU EM - 6712 PMID- 5980692 SO - Am J Proctol 1966 Dec;17(6):480-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67124690 AU - Doherty PC TI - Comparison of direct microscopic and guinea pig inoculation techniques for demonstrating leptospiras in bovine urine. LA - Eng MH - Animal MH - *Antibody Formation MH - Cattle MH - Centrifugation MH - Comparative Study MH - Guinea Pigs MH - *Leptospira/*isolation & purification MH - Leptospirosis/immunology PT - JOURNAL ARTICLE DA - 670519 DP - 1966 Dec IS - 0005-0423 TA - Aust Vet J PG - 466-7 SB - M CY - AUSTRALIA IP - 12 VI - 42 JC - 9IE EM - 6707 PMID- 5962489 SO - Aust Vet J 1966 Dec;42(12):466-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [156 medline neighbors] UI - 67249325 AU - Fujikura T TI - Studies on leptospiral colony formation in bottle culture: conditions favoring Leptospira icterohaemorrhagiae colony formation. LA - Eng MH - Bacteriological Techniques MH - Culture Media MH - Leptospira interrogans/growth & development PT - JOURNAL ARTICLE DA - 671111 DP - 1966 Dec IS - 0021-5295 TA - Nippon Juigaku Zasshi PG - 297-306 CY - JAPAN IP - 6 VI - 28 JC - KRJ EM - 6712 PMID- 5342480 CU - 90 SO - Nippon Juigaku Zasshi 1966 Dec;28(6):297-306 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67083761 AU - Torten M AU - Shenberg E AU - Van der Hoeden J TI - The use of immunofluorescence in the diagnosis of human leptospirosis by a genus-specific antigen. LA - Eng MH - *Antigens MH - *Fluorescent Antibody Technique MH - Human MH - Leptospirosis/*diagnosis MH - Species Specificity PT - JOURNAL ARTICLE DA - 670322 DP - 1966 Dec IS - 0022-1899 TA - J Infect Dis PG - 537-43 SB - A SB - M CY - UNITED STATES IP - 5 VI - 116 JC - IH3 EM - 6705 PMID- 5334248 CU - 90 SO - J Infect Dis 1966 Dec;116(5):537-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67259817 AU - Hruzik J AU - Ujhazyova-Kralikova D AU - Mathernova V AU - Sobota K TI - [Sequellae following meningoencephalitis due to tick-borne encephalitis virus and leptospira] LA - Slo MH - Adolescence MH - Adult MH - *Encephalitis Viruses, Tick-Borne MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Meningoencephalitis/*complications MH - Middle Age PT - JOURNAL ARTICLE DA - 671119 DP - 1966 Nov 15 IS - 0006-9248 TA - Bratisl Lek Listy PG - 545-9 CY - CZECHOSLOVAKIA IP - 9 VI - 46 JC - B5N EM - 6712 PMID- 5981441 TT - Nasledky po meningoencefalitidach sposobenych virusom kliestovej encefalitidy a leptospirami. SO - Bratisl Lek Listy 1966 Nov 15;46(9):545-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 67059126 AU - Samson RI AU - Pillay TS TI - Leptospirosis in Cape Town. LA - Eng MH - Case Report MH - Human MH - Male MH - Middle Age MH - South Africa MH - *Weil's Disease PT - JOURNAL ARTICLE DA - 670307 DP - 1966 Nov 12 IS - 0038-2469 TA - S Afr Med J PG - 1010-1 SB - M CY - SOUTH AFRICA IP - 41 VI - 40 JC - U4R EM - 6704 PMID- 5955088 SO - S Afr Med J 1966 Nov 12;40(41):1010-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69282413 AU - Burov AI AU - Kozlova VP TI - [Leptospirosis morbidity in the Odessa region] LA - Rus MH - Animal MH - Animal Diseases/epidemiology MH - Cattle MH - Cattle Diseases/epidemiology MH - Horse Diseases/epidemiology MH - Horses MH - Human MH - Leptospirosis/*epidemiology MH - Ukraine PT - JOURNAL ARTICLE DA - 691021 DP - 1966 Nov TA - Zh Mikrobiol Epidemiol Immunobiol PG - 145-6 SB - M CY - USSR IP - 11 VI - 43 JC - Y9O EM - 6912 PMID- 6012403 CU - 89 TT - Leptospirovnye zabolevaniia v Odesskoi oblasti. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Nov;43(11):145-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68396189 AU - Petrov VF AU - Bezborodkin NS TI - [Simultaneous immunization of swine against plague, erysipelas and leptospirosis] LA - Rus MH - Animal MH - Erysipelothrix Infections/*veterinary MH - Leptospirosis/*veterinary MH - Pasteurella Infections/*veterinary MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/*veterinary MH - Vaccines PT - JOURNAL ARTICLE DA - 681017 DP - 1966 Nov IS - 0042-4846 TA - Veterinariia PG - 35-7 CY - USSR IP - 11 VI - 43 JC - XCC EM - 6812 PMID- 6012060 CU - 85 TT - Odnovremennaia immunizatsiia svinei protiv chumy, rozhi i leptospiroza. SO - Veterinariia 1966 Nov;43(11):35-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68353026 AU - Mastrangelo P TI - [Some laboratory data on leptospirosis in the dog] LA - Ita MH - Animal MH - Bilirubin/blood MH - Blood Cell Count MH - Blood Glucose/analysis MH - Blood Protein Electrophoresis MH - *Dog Diseases MH - Dogs MH - Hemoglobinometry MH - Leptospirosis/*veterinary MH - Liver Function Tests MH - Nitrogen/blood MH - Weil's Disease/*veterinary PT - JOURNAL ARTICLE DA - 680913 DP - 1966 Nov-Dec IS - 0001-6136 TA - Acta Med Vet (Napoli) PG - 655-73 CY - ITALY IP - 6 VI - 12 JC - 15O EM - 6811 PMID- 6012008 CU - 85 TT - Alcuni dati di laboratorio nella leptospirosi del cane. SO - Acta Med Vet (Napoli) 1966 Nov-Dec;12(6):655-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68329323 AU - Castro AF de AU - Rosa CA AU - Almeida WF de AU - Troise C TI - [Research of antileptospiral antibodies among butchers in some municipalities of the State of Sao Paulo] LA - Por MH - Animal MH - Brazil MH - Cattle MH - Food Microbiology MH - Human MH - Leptospirosis/*immunology MH - Occupational Diseases/*blood MH - Swine MH - Treponema/*immunology PT - JOURNAL ARTICLE DA - 680906 DP - 1966 Nov-Dec IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 287-90 CY - BRAZIL IP - 6 VI - 8 JC - S9D EM - 6810 PMID- 6011989 CU - 85 TT - Pesquisa de aglutininas anti-leptospira entre magarefes em alguns municipios do estado de Sao Paulo. SO - Rev Inst Med Trop Sao Paulo 1966 Nov-Dec;8(6):287-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69282409 AU - Samedov AS TI - [The serologic characteristics of the protein and polysaccharide fractions of a complex antigen isolated from leptospira] LA - Rus MH - Antigens/*analysis MH - *Bacterial Proteins MH - Chemistry MH - Complement Fixation Tests MH - English Abstract MH - Leptospira/*immunology MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/diagnosis MH - *Polysaccharides, Bacterial MH - Species Specificity PT - JOURNAL ARTICLE DA - 691021 DP - 1966 Nov TA - Zh Mikrobiol Epidemiol Immunobiol PG - 13-7 SB - M CY - USSR IP - 11 VI - 43 JC - Y9O EM - 6912 PMID- 6004964 CU - 89 TT - Serologicheskaia kharakteristika bolkovoi i polisakharidnoi fraktsii kompleksnogo antigena, vydelennogo iz leptospir. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Nov;43(11):13-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 68156448 AU - Parnas J AU - Poplawski S AU - Cybalska M TI - [Chemotypes, serotypes and infrared types of leptospirae] LA - Ger MH - Antigens/analysis MH - Carbohydrates/metabolism MH - Chromatography, Paper MH - Leptospira/*analysis/metabolism MH - Leptospira canicola/*analysis MH - Spectrophotometry PT - JOURNAL ARTICLE DA - 680501 DP - 1966 Nov IS - 0003-9144 TA - Arch Hyg Bakteriol PG - 565-9 SB - M CY - GERMANY, WEST IP - 6 VI - 150 JC - 78G EM - 6806 PMID- 5991785 TT - Die Chemotypen, Serotypen und die Infrarottypen der Leptospiren. SO - Arch Hyg Bakteriol 1966 Nov;150(6):565-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 67215107 AU - Osechinskii IV AU - Man'ko VM TI - [Comparison of the reactions of hemopoietic stems on primary immunization in two inbred lines of mice] LA - Rus MH - Animal MH - *Antibody Formation MH - Immunization MH - Leptospira MH - Lymph Nodes/*metabolism MH - Lymphocytes MH - Male MH - Mice MH - Plasma Cells MH - Spleen/*cytology PT - JOURNAL ARTICLE DA - 671017 DP - 1966 Nov-Dec IS - 0041-3771 TA - Tsitologiia PG - 763-7 SB - M CY - USSR IP - 6 VI - 8 JC - WGW EM - 6711 PMID- 5974470 TT - Sravenie reaktsii krovetvornykh rostkov na pervichnuiu immunizatsiiu u dvukh inbrednykh linii myshei. SO - Tsitologiia 1966 Nov-Dec;8(6):763-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67181245 AU - Ringen L TI - Response of erythrocytes to Leptospira pomona hemolysins during infection. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*blood/immunology MH - Erythrocytes/*drug effects MH - *Goats MH - Hemolysins/*pharmacology MH - *Leptospira MH - Leptospirosis/blood/immunology/*veterinary MH - Male PT - JOURNAL ARTICLE DA - 670911 DP - 1966 Nov IS - 0002-9645 TA - Am J Vet Res PG - 1629-32 SB - M CY - UNITED STATES IP - 121 VI - 27 JC - 40C EM - 6710 PMID- 5971616 SO - Am J Vet Res 1966 Nov;27(121):1629-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67247035 AU - Parnas J AU - Cybulska MT TI - [Morphology of leptospira] LA - Pol MH - Leptospira/*cytology PT - JOURNAL ARTICLE PT - REVIEW DA - 671105 DP - 1966 Nov-Dec IS - 0032-5449 TA - Postepy Hig Med Dosw PG - 859-71 CY - POLAND IP - 6 VI - 20 JC - PEU EM - 6712 RF - 28 PMID- 5342223 CU - 90 TT - Morfologia leptospir. SO - Postepy Hig Med Dosw 1966 Nov-Dec;20(6):859-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [161 medline neighbors] UI - 67200741 AU - Allinne M AU - Marx R TI - [The diagnosis of borreliosis by immunofluorescence] LA - Fre MH - Adolescence MH - Adult MH - Borrelia Infections/*diagnosis MH - Child MH - Diagnosis, Differential MH - Female MH - Fluorescent Antibody Technique MH - Human MH - Leptospirosis/diagnosis MH - Male MH - Syphilis Serodiagnosis MH - Treponemal Infections/diagnosis PT - JOURNAL ARTICLE DA - 670924 DP - 1966 Nov IS - 0020-2444 TA - Ann Inst Pasteur (Paris) PG - Suppl:28-35 SB - M CY - FRANCE IP - 5 VI - 111 JC - 58Y EM - 6711 PMID- 5339835 CU - 90 TT - Le diagnostic des borrelioses par immunofluorescence. SO - Ann Inst Pasteur (Paris) 1966 Nov;111(5):Suppl:28-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [209 medline neighbors] UI - 68083949 AU - Toscano F TI - [Considerations on leptospirosis in Italy] LA - Fre MH - Human MH - Italy MH - *Leptospirosis MH - *Weil's Disease PT - JOURNAL ARTICLE PT - REVIEW DA - 680203 DP - 1966 Nov IS - 0017-0321 TA - G Mal Infett Parassit PG - 713-23 CY - ITALY IP - 11 VI - 18 JC - FD7 EM - 6803 RF - 45 PMID- 4863496 CU - 90 TT - Considerations sur les leptospiroses in Italie. SO - G Mal Infett Parassit 1966 Nov;18(11):713-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 69064418 AU - Mezhennyi AM TI - [Clinical and epidemiological observations in a leptospirosis focus] LA - Rus MH - Agglutination Tests MH - Animal MH - Baths MH - Disease Reservoirs MH - Human MH - Leptospirosis/blood/epidemiology/*etiology MH - Russia MH - Swine MH - Zoonoses PT - JOURNAL ARTICLE DA - 690205 DP - 1966 Nov IS - 0038-5077 TA - Sov Med PG - 93-6 CY - USSR IP - 11 VI - 29 JC - UW7 EM - 6903 PMID- 4235820 CU - 92 TT - Kliniko-epidemiologicheskie nabliudeniia v ochage leptospiroza. SO - Sov Med 1966 Nov;29(11):93-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [149 medline neighbors] UI - 67245605 AU - Cerva L TI - [Standard cultivation of Leptospira on the Korthof medium without serum] LA - Cze MH - Albumins MH - Animal MH - Cattle MH - *Culture Media MH - In Vitro MH - Leptospira/*growth & development PT - JOURNAL ARTICLE DA - 671105 DP - 1966 Nov IS - 0032-6720 TA - Cesk Epidemiol Mikrobiol Imunol PG - 346-8 CY - CZECHOSLOVAKIA IP - 6 VI - 15 JC - CSH EM - 6712 PMID- 4227261 CU - 92 TT - Standardni kultivace leptospir na Korthofove mediu bez sera. SO - Cesk Epidemiol Mikrobiol Imunol 1966 Nov;15(6):346-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68157071 AU - Teodorovici G AU - Ivan A AU - Oana C AU - Bercovici C AU - Burduja A AU - Zvoristeanu V AU - Butuc A TI - [Immuno-epidemiological research on the incidence of leptospirosis in humans and animals in the year 1965 in the Jijia-Prut region] LA - Rum MH - Animal MH - Antibodies/*analysis MH - Cattle MH - Cattle Diseases/*epidemiology MH - Human MH - Leptospirosis/*epidemiology/*immunology MH - Romania MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 680501 DP - 1966 Oct-Sep IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 953-62 CY - ROMANIA IP - 4 VI - 70 JC - SHP EM - 6806 PMID- 6011449 CU - 88 TT - Cercetari imuno-epidemiologice privind incidenta leptospirozei la om si animale in anul 1965 n zona Jijia-Prut. SO - Rev Med Chir Soc Med Nat Iasi 1966 Oct-Sep;70(4):953-62 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67241660 AU - Kemenes F AU - Szeky A TI - Leptospira sejro infection of albino mice in Hungary (eradication of leptospires from the infected mouse stocks). LA - Eng MH - Animal MH - Leptospirosis/*veterinary MH - *Mice PT - JOURNAL ARTICLE DA - 671030 DP - 1966 Oct TA - Zentralbl Veterinarmed [B] PG - 591-600 CY - GERMANY, WEST IP - 6 VI - 13 JC - Y72 EM - 6712 PMID- 6009373 CU - 89 SO - Zentralbl Veterinarmed [B] 1966 Oct;13(6):591-600 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 69161591 AU - Kiktenko VS AU - Troshin KA TI - [On the ultra-thin structure of Leptospira] LA - Rus MH - Cytoplasm MH - Leptospira interrogans/*cytology MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 690529 DP - 1966 Oct TA - Zh Mikrobiol Epidemiol Immunobiol PG - 5-7 SB - M CY - USSR IP - 10 VI - 43 JC - Y9O EM - 6907 PMID- 6003880 CU - 89 TT - Ob ul'tratonkoi strukture leptospir. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Oct;43(10):5-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68157074 AU - Brebenel G AU - Vasilache G AU - Bercovici C AU - Burduja A TI - [Considerations on a focus of human leptospirosis due to bathing in a polluted stream] LA - Rum MH - *Disease Reservoirs MH - Human MH - Leptospirosis/*etiology MH - Romania MH - *Swimming MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 680501 DP - 1966 Oct-Sep IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 977-83 CY - ROMANIA IP - 4 VI - 70 JC - SHP EM - 6806 PMID- 5991889 TT - Consideratii asupra unui focar de leptospiroza umana de origine hidrica. SO - Rev Med Chir Soc Med Nat Iasi 1966 Oct-Sep;70(4):977-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67132365 AU - Sandborn EB AU - Cote MG AU - Viallet A TI - Electron microscopy of a human liver in Weil's disease (leptospirosis icterohaemorrhagica). LA - Eng MH - Biopsy MH - Cytoplasmic Granules MH - Human MH - Male MH - Microscopy, Electron MH - Mitochondria MH - Weil's Disease/*pathology PT - JOURNAL ARTICLE DA - 670616 DP - 1966 Oct TA - J Pathol Bacteriol PG - 369-74 CY - ENGLAND IP - 2 VI - 92 JC - JLJ EM - 6708 PMID- 5964375 CU - 89 SO - J Pathol Bacteriol 1966 Oct;92(2):369-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67082390 AU - Murthy VS AU - Rao AN AU - Parvathi G TI - A case of leptospirosis from Kurnool. LA - Eng MH - Adult MH - Case Report MH - Female MH - Human MH - India MH - *Leptospirosis PT - JOURNAL ARTICLE DA - 670319 DP - 1966 Oct IS - 0019-5359 TA - Indian J Med Sci PG - 716-8 CY - INDIA IP - 10 VI - 20 JC - GJP EM - 6705 PMID- 5956669 SO - Indian J Med Sci 1966 Oct;20(10):716-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 67049821 AU - Stalheim OH TI - Leptospiral selection, growth, and virulence in synthetic medium. LA - Eng MH - Animal MH - Culture Media MH - Guinea Pigs MH - Hamsters MH - Leptospira/*growth & development/*pathogenicity MH - Serum Albumin/metabolism MH - Surface-Active Agents/pharmacology MH - Swine MH - Trypsin/pharmacology MH - Virulence PT - JOURNAL ARTICLE DA - 670208 DP - 1966 Oct IS - 0021-9193 TA - J Bacteriol PG - 946-51 SB - M CY - UNITED STATES IP - 4 VI - 92 JC - HH3 EM - 6703 PMID- 5926762 SO - J Bacteriol 1966 Oct;92(4):946-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67049441 AU - Evins GM AU - West B AU - Reynolds GH TI - Evaluation of leptospiral macroscopic-slide test antigens with reference and human sera. LA - Eng MH - Agglutination Tests MH - Antibodies MH - Antigens MH - Human MH - Leptospirosis/*immunology MH - Microscopy PT - JOURNAL ARTICLE DA - 670205 DP - 1966 Oct IS - 0017-9035 TA - Health Lab Sci PG - 235-50 SB - M CY - UNITED STATES IP - 4 VI - 3 JC - G2C EM - 6703 PMID- 5926623 SO - Health Lab Sci 1966 Oct;3(4):235-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 67181903 AU - Smith RE AU - Hench EC AU - Reynolds IM TI - Experimental leptospirosis in pregnant ewes. VI. Immunofluorescence in the diagnosis of fetal leptospirosis. LA - Eng MH - Animal MH - Female MH - Fetal Diseases/diagnosis/*veterinary MH - Fluorescent Antibody Technique MH - Leptospirosis/*diagnosis MH - Pregnancy MH - Pregnancy Complications, Infectious/diagnosis/*veterinary MH - Sheep MH - Sheep Diseases/*diagnosis PT - JOURNAL ARTICLE DA - 670912 DP - 1966 Oct IS - 0010-8901 TA - Cornell Vet PG - 640-7 SB - M CY - UNITED STATES IP - 4 VI - 56 JC - DRI EM - 6710 PMID- 5339553 CU - 90 SO - Cornell Vet 1966 Oct;56(4):640-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [159 medline neighbors] UI - 67023862 AU - Odabashian ZA TI - [Water fever (un-icteric leptospirosis) and its prevention] LA - Rus MH - Leptospirosis/prevention & control MH - Nursing PT - JOURNAL ARTICLE DA - 670112 DP - 1966 Oct TA - Med Sestra PG - 19-21 SB - N CY - USSR IP - 10 VI - 25 JC - MFP EM - 6702 PMID- 5179672 CU - 89 LI - N TT - Vodnaia likhoradka (bezzeheltushnyi leptospiroz) i ee preduprezhdenie. SO - Med Sestra 1966 Oct;25(10):19-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67240173 AU - Mittermayer T AU - Plesko I TI - [The 1st case of Leptospira ballum infection in Czechoslovakia] LA - Slo MH - Adult MH - Czechoslovakia MH - Human MH - Leptospirosis/*epidemiology MH - Male PT - JOURNAL ARTICLE DA - 671028 DP - 1966 Sep 15 IS - 0006-9248 TA - Bratisl Lek Listy PG - 296-8 CY - CZECHOSLOVAKIA IP - 5 VI - 46 JC - B5N EM - 6712 PMID- 5976387 CU - 88 TT - Prvy pripad Leptospirozy ballum v nasom state. SO - Bratisl Lek Listy 1966 Sep 15;46(5):296-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 70010515 AU - Grannikova SA AU - Smirin VM AU - Vorob'eva RN TI - [Characteristics of natural foci of leptospirosis in central Priamur'e] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Disease Reservoirs/*epidemiology MH - English Abstract MH - Leptospirosis/*epidemiology/veterinary MH - Mice MH - Rats MH - Rodent Diseases/*epidemiology MH - Siberia MH - Swine MH - Swine Diseases/epidemiology PT - JOURNAL ARTICLE DA - 691203 DP - 1966 Sep TA - Zh Mikrobiol Epidemiol Immunobiol PG - 75-7 SB - M CY - USSR IP - 9 VI - 43 JC - Y9O EM - 7001 PMID- 6012408 CU - 89 TT - Materialy k kharakteristike prirodnykh ocharov leptospiroza v srednem priamur'e. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Sep;43(9):75-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68158154 AU - Shmatkova AI TI - [A study of experimental swine leptospirosis] LA - Rus MH - Age Factors MH - Animal MH - Leptospirosis/*veterinary MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 680501 DP - 1966 Sep IS - 0042-4846 TA - Veterinariia PG - 37-8 CY - USSR IP - 9 VI - 43 JC - XCC EM - 6806 PMID- 6011470 CU - 85 TT - Izuchenie eksperimental'nogo leptospiroza porosiat. SO - Veterinariia 1966 Sep;43(9):37-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67240154 AU - Sturdza N AU - Nicolesco M AU - Vasilesco T AU - Safiresco D TI - [Abattoirs and leptospirosis. Serological study of slaughterhouse employees and animals] LA - Fre MH - *Abattoirs MH - Adult MH - Animal MH - Cattle MH - Cattle Diseases MH - Female MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Occupational Diseases/*epidemiology MH - Swine MH - Swine Diseases PT - JOURNAL ARTICLE DA - 671028 DP - 1966 Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 635-44 CY - ROMANIA IP - 3 VI - 25 JC - 8EM EM - 6712 PMID- 6009229 CU - 88 TT - Abattoirs et leptospiroses. Controle serologique des employes et des animaux d'abattage. SO - Arch Roum Pathol Exp Microbiol 1966 Sep;25(3):635-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70010516 AU - Kanareikina SK AU - Cherukulam P TI - [A solid culture medium for growing leptospira] LA - Rus MH - *Culture Media MH - English Abstract MH - Leptospira/growth & development/*isolation & purification MH - Methods PT - JOURNAL ARTICLE DA - 691203 DP - 1966 Sep TA - Zh Mikrobiol Epidemiol Immunobiol PG - 77-80 SB - M CY - USSR IP - 9 VI - 43 JC - Y9O EM - 7001 PMID- 6005091 CU - 90 TT - Plotnaia pitatel'naia sreda dlia vyrashchivaniia leptospir. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Sep;43(9):77-80 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67180229 AU - Wolff JW AU - Bohlander HJ TI - A new serotype of Leptospira, belonging to the autumnalis serogroup. LA - Eng MH - Absorption MH - Agglutination Tests MH - In Vitro MH - Leptospira/*classification/*immunology PT - JOURNAL ARTICLE DA - 670907 DP - 1966 Sep IS - 0041-3232 TA - Trop Geogr Med PG - 247-9 SB - M CY - NETHERLANDS IP - 3 VI - 18 JC - WGJ EM - 6710 PMID- 5971409 SO - Trop Geogr Med 1966 Sep;18(3):247-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67180228 AU - Chernukha YG TI - Antigenic analysis of Leptospira strains, belonging to the Pomona group. LA - Eng MH - Absorption MH - Agglutination Tests MH - Antigens MH - Immune Sera MH - In Vitro MH - Leptospira/*classification/*immunology PT - JOURNAL ARTICLE DA - 670907 DP - 1966 Sep IS - 0041-3232 TA - Trop Geogr Med PG - 242-6 SB - M CY - NETHERLANDS IP - 3 VI - 18 JC - WGJ EM - 6710 PMID- 5971408 SO - Trop Geogr Med 1966 Sep;18(3):242-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 67040456 AU - Schnurrenberger PR AU - Masterson RA TI - The prevalence of antibodies against selected zoonotic diseases in abattoir workers. LA - Eng MH - *Abattoirs MH - Adult MH - Animal MH - Antibodies MH - Brucellosis/immunology MH - Human MH - Leptospirosis/immunology MH - Occupational Diseases/*epidemiology MH - Ohio MH - Ornithosis/immunology MH - Q Fever/immunology MH - Weil's Disease/immunology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 670122 DP - 1966 Sep IS - 0003-9896 TA - Arch Environ Health PG - 336-9 SB - A SB - M CY - UNITED STATES IP - 3 VI - 13 JC - 6YO EM - 6703 PMID- 5950875 CU - 88 SO - Arch Environ Health 1966 Sep;13(3):336-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67014273 AU - Clark LG AU - Varela-Diaz VM AU - Sulzer CR AU - Marshak RR AU - Hollister CJ TI - Leptospirosis in Nicaragua: preliminary report on the first year of study. LA - Eng MH - Animal MH - *Animals, Domestic MH - Cattle MH - Cattle Diseases/*epidemiology MH - Leptospirosis/*epidemiology/*veterinary MH - *Mammals MH - Nicaragua PT - JOURNAL ARTICLE DA - 661226 DP - 1966 Sep IS - 0002-9637 TA - Am J Trop Med Hyg PG - 735-42 SB - A SB - M CY - UNITED STATES IP - 5 VI - 15 JC - 3ZQ EM - 6702 PMID- 5950520 CU - 88 SO - Am J Trop Med Hyg 1966 Sep;15(5):735-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67017789 AU - Wilson TS TI - Recent observations on leptospirosis in Northern Ireland and their bearing on current diagnostic methods. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Agglutination MH - Female MH - Human MH - Leptospirosis/*diagnosis/*epidemiology/immunology MH - Male MH - Middle Age MH - Northern Ireland MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 661229 DP - 1966 Sep IS - 0021-9746 TA - J Clin Pathol PG - 415-23 SB - A SB - M CY - ENGLAND IP - 5 VI - 19 JC - HT3 EM - 6702 PMID- 5919352 CU - 88 SO - J Clin Pathol 1966 Sep;19(5):415-23 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [211 medline neighbors] UI - 66170981 AU - Edwards GA AU - Domm BM TI - Leptospirosis. II. LA - Eng MH - Human MH - *Leptospirosis MH - *Weil's Disease PT - JOURNAL ARTICLE PT - REVIEW DA - 661017 DP - 1966 Sep IS - 0025-7583 TA - Med Times PG - 1086-95 CY - UNITED STATES IP - 9 VI - 94 JC - MGE EM - 6612 RF - 76 PMID- 5329727 CU - 90 SO - Med Times 1966 Sep;94(9):1086-95 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68158183 AU - Novikova VN AU - Levshina VD TI - [A comparative assessment of various methods of laboratory diagnosis of leptospirosis] LA - Rus MH - Agglutination Tests MH - Animal MH - Bacteriological Techniques MH - Comparative Study MH - Fluorescent Antibody Technique MH - Leptospirosis/*diagnosis MH - Rabbits PT - JOURNAL ARTICLE DA - 680501 DP - 1966 Sep IS - 0042-4846 TA - Veterinariia PG - 90-1 CY - USSR IP - 9 VI - 43 JC - XCC EM - 6806 PMID- 4867704 CU - 90 TT - Sravnitel'naia otsenka razlichnykh metodov laboratornoi diagnostiki leptospirozov. SO - Veterinariia 1966 Sep;43(9):90-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 67178831 AU - York CJ TI - Combined viral and bacterial antigens for canine vaccines. LA - Eng MH - Adenoviruses, Canine MH - Animal MH - *Antigens MH - Distemper/*prevention & control MH - Distemper Virus, Canine MH - Dog Diseases/*prevention & control MH - Dogs MH - Hepatitis, Animal/*prevention & control MH - Leptospira canicola MH - Leptospirosis/prevention & control MH - Measles Vaccine MH - Vaccination/veterinary MH - *Viral Vaccines PT - JOURNAL ARTICLE DA - 670907 DP - 1966 Sep 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 681-5 SB - M CY - UNITED STATES IP - 5 VI - 149 JC - HAV EM - 6710 PMID- 4291220 CU - 93 SO - J Am Vet Med Assoc 1966 Sep 1;149(5):681-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [37 medline neighbors] UI - 67173219 AU - Yanagawa R AU - Faine S TI - Morphological and serological analysis of leptospiral structure. LA - Eng MH - Agglutination MH - Amino Sugars/analysis MH - Cell Wall MH - Deoxyribonucleases MH - Glucosamine/analysis MH - Immunodiffusion MH - Leptospira interrogans/*cytology/*immunology MH - Microscopy, Electron MH - Ribonucleases MH - Surface-Active Agents MH - Trypsin PT - JOURNAL ARTICLE DA - 670826 DP - 1966 Aug 20 IS - 0028-0836 TA - Nature PG - 823-6 SB - M CY - ENGLAND IP - 51 VI - 211 JC - NSC EM - 6710 PMID- 4961309 CU - 91 SO - Nature 1966 Aug 20;211(51):823-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67055991 AU - Yamaguchi M AU - Nagano H AU - Nakamoto N AU - Shigematsu T TI - [Hepatic function in leptospirosis icterohaemorrhagica] LA - Jpn MH - *Adult MH - Aminotransferases/*blood MH - Case Report MH - Hepatitis A/*physiopathology MH - Human MH - Liver/*physiopathology MH - *Liver Function Tests MH - Male MH - *Middle Age MH - Weil's Disease/*physiopathology PT - JOURNAL ARTICLE DA - 670301 DP - 1966 Aug 10 IS - 0021-5384 TA - Nippon Naika Gakkai Zasshi PG - 432-8 CY - JAPAN IP - 5 VI - 55 JC - IPZ EM - 6704 PMID- 6005708 CU - 85 SO - Nippon Naika Gakkai Zasshi 1966 Aug 10;55(5):432-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67020402 AU - Lawson JH AU - Michna SW TI - Canicola fever in man and animals. LA - Eng MH - Adolescence MH - Adult MH - Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/epidemiology MH - Cerebrospinal Fluid/microbiology MH - Human MH - Leptospira/immunology MH - *Leptospira canicola MH - Leptospirosis/*epidemiology/*veterinary MH - Scotland MH - Swine MH - Swine Diseases/*epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 670106 DP - 1966 Aug 6 IS - 0007-1447 TA - Br Med J PG - 336-40 SB - A SB - M CY - ENGLAND IP - 509 VI - 2 JC - B4W EM - 6702 PMID- 5950758 CU - 88 SO - Br Med J 1966 Aug 6;2(509):336-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67216991 AU - Parnas J AU - Cybulska MT TI - A new serotype: Leptospira polonica. LA - Eng MH - Animal MH - Insectivora MH - Leptospira/*classification/immunology/*isolation & purification MH - Poland PT - JOURNAL ARTICLE DA - 671020 DP - 1966 Aug TA - Zentralbl Veterinarmed [B] PG - 388-91 CY - GERMANY, WEST IP - 4 VI - 13 JC - Y72 EM - 6711 PMID- 6008907 CU - 89 SO - Zentralbl Veterinarmed [B] 1966 Aug;13(4):388-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70251571 AU - Petrov RV AU - Man'ko VM AU - Panteleev EI TI - [Interstrain differences in antibody production in inbred mice immunized with 1 or 2 antigens] LA - Rus MH - Animal MH - *Antibody Formation MH - Antibody Specificity MH - *Antigens MH - English Abstract MH - Erythrocytes MH - Immunization MH - Leptospira MH - Mice MH - Sheep PT - JOURNAL ARTICLE DA - 700919 DP - 1966 Aug IS - 0006-4041 TA - Biull Eksp Biol Med PG - 70-4 SB - M CY - USSR IP - 8 VI - 62 JC - A74 EM - 7011 PMID- 6005479 TT - Mezhlineinye razlichiia antitelogeneza u inbrednykh myshei immunizirovannykh odnim ili dvumia antigenami. SO - Biull Eksp Biol Med 1966 Aug;62(8):70-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69237871 AU - Mazurin ND AU - Anokhin II TI - [The role of cows in the formation of foci of jaundice-less leptospirosis in the Amur region] LA - Rus MH - Animal MH - *Cattle MH - *Disease Vectors MH - Human MH - Leptospirosis/*etiology MH - Siberia PT - JOURNAL ARTICLE DA - 690904 DP - 1966 Aug TA - Zh Mikrobiol Epidemiol Immunobiol PG - 147 SB - M CY - USSR IP - 8 VI - 43 JC - Y9O EM - 6910 PMID- 6004755 CU - 89 TT - Rol' korov v formirovanii ochagov bezzheltushnykh lept o spirozov v amurskoi oblasti. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Aug;43(8):147 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68202637 AU - Kats LN AU - Konstantinova ND TI - [Some data on the submicroscopic structure of Leptospira] LA - Rus MH - Cell Membrane MH - Leptospira/*cytology MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 680610 DP - 1966 Aug 1 IS - 0002-3264 TA - Dokl Akad Nauk SSSR PG - 950-1 SB - M CY - USSR IP - 4 VI - 169 JC - EBK EM - 6807 PMID- 5994256 TT - Nekotorye dannye o submikroskopicheskoi strukture Leptospir. SO - Dokl Akad Nauk SSSR 1966 Aug 1;169(4):950-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67216990 AU - Parnas J AU - Poplawski S AU - Cybulska M TI - Research on the antigenic structure of leptospira by infrared spectrophotometry. LA - Eng MH - *Antigens MH - Infrared Rays MH - Leptospira/*immunology MH - Spectrophotometry PT - JOURNAL ARTICLE DA - 671020 DP - 1966 Aug TA - Zentralbl Veterinarmed [B] PG - 377-87 CY - GERMANY, WEST IP - 4 VI - 13 JC - Y72 EM - 6711 PMID- 5975113 CU - 89 SO - Zentralbl Veterinarmed [B] 1966 Aug;13(4):377-87 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 67216989 AU - Parnas J AU - Pinkiewicz H TI - The influence of Leptospirae and their toxins on tissue culture and the possibility of differentiation of the serotypes. LA - Eng MH - Leptospira/immunology/*pathogenicity MH - *Tissue Culture MH - Toxins/*pharmacology PT - JOURNAL ARTICLE DA - 671020 DP - 1966 Aug TA - Zentralbl Veterinarmed [B] PG - 369-76 CY - GERMANY, WEST IP - 4 VI - 13 JC - Y72 EM - 6711 PMID- 5975112 CU - 89 SO - Zentralbl Veterinarmed [B] 1966 Aug;13(4):369-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66151926 AU - Edwards GA AU - Domm BM TI - Leptospirosis. LA - Eng MH - Human MH - Leptospirosis/*diagnosis MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 660921 DP - 1966 Aug IS - 0025-7583 TA - Med Times PG - 903-13 contd CY - UNITED STATES IP - 8 VI - 94 JC - MGE EM - 6611 PMID- 5938844 SO - Med Times 1966 Aug;94(8):903-13 contd ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 69237869 AU - Tagi-Zade TA AU - Borisova LP TI - [Leptospira carrier state among nutrias (Myocastor coypus Moll)] LA - Rus MH - Animal MH - Azerbaijan MH - Carrier State/*epidemiology MH - *Disease Reservoirs MH - Leptospirosis/*epidemiology/etiology MH - *Rodentia PT - JOURNAL ARTICLE DA - 690904 DP - 1966 Aug TA - Zh Mikrobiol Epidemiol Immunobiol PG - 146 SB - M CY - USSR IP - 8 VI - 43 JC - Y9O EM - 6910 PMID- 4240244 CU - 92 TT - Leptospironositel'stvo sredi nutrii (Myocastor coypus Moll) SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Aug;43(8):146 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67173516 AU - Mitchell D AU - Robertson A AU - Corner AH AU - Boulanger P TI - Some observations on the diagnosis and epidemiology of leptospirosis in swine. LA - Eng MH - Agglutination Tests MH - Animal MH - Guinea Pigs MH - Histological Techniques MH - Leptospira/isolation & purification MH - Leptospirosis/diagnosis/*epidemiology/*veterinary MH - Swine MH - Swine Diseases/*diagnosis MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 670826 DP - 1966 Aug IS - 0316-5957 TA - Can J Comp Med Vet Sci PG - 211-7 SB - M CY - CANADA IP - 8 VI - 30 JC - BCY EM - 6710 PMID- 4226190 CU - 92 SO - Can J Comp Med Vet Sci 1966 Aug;30(8):211-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [162 medline neighbors] UI - 66152681 AU - Schonell ME AU - Brotherston JG AU - Burnett RC AU - Campbell J AU - Coghlan JD AU - Moffat MA AU - Norval J AU - Sutherland JA TI - Occupational infections in the Edinburgh abattoir. LA - Eng MH - *Abattoirs MH - Animal MH - Arbovirus Infections/epidemiology MH - Brucellosis/epidemiology MH - Human MH - Leptospirosis/epidemiology MH - Occupational Diseases/diagnosis/*etiology MH - Q Fever/epidemiology MH - Scotland MH - Serodiagnosis MH - Zoonoses/diagnosis/*epidemiology PT - JOURNAL ARTICLE DA - 660925 DP - 1966 Jul 16 IS - 0007-1447 TA - Br Med J PG - 148-50 SB - A SB - M CY - ENGLAND VI - 5506 JC - B4W EM - 6611 PMID- 5949409 CU - 88 SO - Br Med J 1966 Jul 16;5506:148-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 66173279 AU - Hansman D AU - Murphy AM AU - Wannan JS AU - Woolard TJ AU - Boger JR TI - Q fever, brucellosis and leptospirosis among abattoir workers in New South Wales. LA - Eng MH - *Abattoirs MH - Adult MH - Agglutination Tests MH - Australia MH - Brucellosis/metabolism MH - Complement Fixation Tests MH - Human MH - Leptospirosis/*epidemiology MH - Occupational Diseases/*epidemiology MH - Q Fever/epidemiology PT - JOURNAL ARTICLE DA - 661023 DP - 1966 Jul 2 IS - 0025-729X TA - Med J Aust PG - 20-3 SB - M CY - AUSTRALIA IP - 1 VI - 2 JC - M26 EM - 6612 PMID- 5947538 CU - 88 SO - Med J Aust 1966 Jul 2;2(1):20-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68133036 AU - Slin'ko VG TI - [Treatment of swine leptospirosis] LA - Rus MH - Animal MH - Anti-Infective Agents/*therapeutic use MH - Leptospirosis/*veterinary MH - Quinolines/*therapeutic use MH - Swine MH - Swine Diseases/*drug therapy PT - JOURNAL ARTICLE DA - 680410 DP - 1966 Jul IS - 0042-4846 TA - Veterinariia PG - 41-3 CY - USSR IP - 7 VI - 43 JC - XCC EM - 6805 PMID- 6011353 CU - 85 TT - Lechenie leptospiroza svinei. SO - Veterinariia 1966 Jul;43(7):41-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67171091 AU - Smith RE AU - Reynolds IM AU - Clark GW TI - Experimental leptospirosis in pregnant ewes. V. Middle uterine artery inoculations. LA - Eng MH - Abortion, Veterinary/etiology MH - Animal MH - Diseases in Twins/veterinary MH - Female MH - Fetal Death/veterinary MH - Fetal Diseases/etiology/*veterinary MH - Leptospirosis/*veterinary MH - Maternal-Fetal Exchange MH - Placenta/microbiology MH - Pregnancy MH - Pregnancy Complications/*veterinary MH - Sheep MH - *Sheep Diseases PT - JOURNAL ARTICLE DA - 670814 DP - 1966 Jul IS - 0010-8901 TA - Cornell Vet PG - 418-26 SB - M CY - UNITED STATES IP - 3 VI - 56 JC - DRI EM - 6710 PMID- 6007832 CU - 85 SO - Cornell Vet 1966 Jul;56(3):418-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67167246 AU - Joseph KM AU - Kalra SL TI - Leptospirosis in India. LA - Eng MH - Animal MH - Cattle MH - Dogs MH - Human MH - India MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology/veterinary MH - Rats MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 670804 DP - 1966 Jul IS - 0019-5340 TA - Indian J Med Res PG - 611-4 CY - INDIA IP - 7 VI - 54 JC - GJF EM - 6709 PMID- 6007619 CU - 88 SO - Indian J Med Res 1966 Jul;54(7):611-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67171305 AU - Vasilache C AU - Brebenel G AU - Oana C AU - Burduja A AU - Bejenzru C AU - Ivan A AU - Teodorovici G AU - Bercovici C TI - [Contributions to the study of morbidity from leptospirosis in the regions of Galati and Iasi. I. Retrospective serologic diagnosis with methods of epidemiological investigation] LA - Rum MH - Agglutination Tests MH - Animal MH - Human MH - Leptospirosis/*diagnosis/*epidemiology MH - Retrospective Studies MH - Romania PT - JOURNAL ARTICLE DA - 670814 DP - 1966 Jul-Sep IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 731-7 CY - ROMANIA IP - 3 VI - 70 JC - SHP EM - 6710 PMID- 5968111 CU - 88 TT - Contributii la studiul morbiditatii prin leptospiroza in regiunile Galati si Iasi. I. Diagnosticul serologic retrospectiv ca metoda de investigatie epidemiologica. SO - Rev Med Chir Soc Med Nat Iasi 1966 Jul-Sep;70(3):731-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67169985 AU - Miller NG AU - Wilson RB TI - Electron microscopy of the liver of the hamster during acute and chronic leptospirosis. LA - Eng MH - Animal MH - Bile Acids and Salts MH - Hamsters MH - Leptospirosis/*pathology/*veterinary MH - Liver/*pathology MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 670814 DP - 1966 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1071-81 SB - M CY - UNITED STATES IP - 119 VI - 27 JC - 40C EM - 6710 PMID- 5967328 SO - Am J Vet Res 1966 Jul;27(119):1071-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 67050625 AU - Berg R AU - Durand DP TI - Freeze-cutting of density gradients. LA - Eng MH - *Freezing MH - Leptospira/enzymology MH - Lipase/analysis MH - Newcastle Disease Virus MH - *Ultracentrifugation MH - *Virology PT - JOURNAL ARTICLE DA - 670220 DP - 1966 Jul IS - 0003-6919 TA - Appl Microbiol PG - 687-9 SB - M CY - UNITED STATES IP - 4 VI - 14 JC - 6K0 EM - 6704 PMID- 5927055 SO - Appl Microbiol 1966 Jul;14(4):687-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67015488 AU - Alterio DL AU - Cunha JC da TI - +Human leptospirosis caused by Leptospira sentot] LA - Por MH - Aged MH - Case Report MH - Human MH - Leptospirosis/*etiology MH - Male PT - JOURNAL ARTICLE DA - 661226 DP - 1966 Jul-Aug IS - 0041-8781 TA - Rev Hosp Clin Fac Med Sao Paulo PG - 199-201 CY - BRAZIL IP - 4 VI - 21 JC - S3L EM - 6702 PMID- 5918169 TT - Leptospirose humana por Leptospira sentot. SO - Rev Hosp Clin Fac Med Sao Paulo 1966 Jul-Aug;21(4):199-201 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67171304 AU - Bejenaru C AU - Cuciureanu G AU - Sirmon E AU - Ioan E AU - Trusca V AU - Burduja A AU - Feller H AU - Pavel S TI - [Comments on the criteria for appraisal of serologic and bacteriologic tests in leptospirosis infections] LA - Rum MH - Animal MH - Bacteriological Techniques MH - Human MH - Leptospira/isolation & purification MH - Leptospirosis/*diagnosis MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 670814 DP - 1966 Jul-Sep IS - 0300-8738 TA - Rev Med Chir Soc Med Nat Iasi PG - 723-9 CY - ROMANIA IP - 3 VI - 70 JC - SHP EM - 6710 PMID- 5338663 CU - 90 TT - Consideratii asupra criteriilor DE APRECIERE A TESTELOR SEROLOGICE .SI BACTERIOLOGICE ?IN DIAGNOSTICUI DE LABORATOR AL INFEC.TILOR LEPTOSPIROTICE. SO - Rev Med Chir Soc Med Nat Iasi 1966 Jul-Sep;70(3):723-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [157 medline neighbors] UI - 67171247 AU - Fujikura T TI - Studies on two colonial types of Leptospira icterohaemorrhagia with special reference to the bottle culture method. LA - Eng MH - Absorption MH - Animal MH - Animals, Newborn MH - Bacteriological Techniques/*instrumentation MH - Guinea Pigs MH - Hamsters MH - Leptospira interrogans/*growth & development/*pathogenicity MH - Mice MH - Rabbits MH - Weil's Disease PT - JOURNAL ARTICLE DA - 670814 DP - 1966 Jul IS - 0021-5139 TA - Jpn J Microbiol PG - 79-83 SB - M CY - JAPAN IP - 2 VI - 10 JC - KMF EM - 6710 PMID- 5338657 CU - 90 SO - Jpn J Microbiol 1966 Jul;10(2):79-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 67170014 AU - Ellinghausen HC Jr TI - The effect of aeration upon the growth of leptospira serotypes. LA - Eng MH - *Air MH - Bacteriological Techniques MH - *Culture Media MH - Leptospira/*growth & development/metabolism PT - JOURNAL ARTICLE DA - 670814 DP - 1966 Jul IS - 0002-9645 TA - Am J Vet Res PG - 975-9 SB - M CY - UNITED STATES IP - 119 VI - 27 JC - 40C EM - 6710 PMID- 5338548 CU - 90 SO - Am J Vet Res 1966 Jul;27(119):975-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 67169995 AU - Ellinghausen HC Jr TI - Continuous recording of the growth of leptospira, staphylococcus, pasteurella, haemophilus, and erysipelothrix species. LA - Eng MH - Erysipelothrix/*growth & development MH - Escherichia coli/growth & development MH - Haemophilus/*growth & development MH - Leptospira/*growth & development MH - Pasteurella/*growth & development MH - Staphylococcus/*growth & development PT - JOURNAL ARTICLE DA - 670814 DP - 1966 Jul IS - 0002-9645 TA - Am J Vet Res PG - 1136-40 SB - M CY - UNITED STATES IP - 119 VI - 27 JC - 40C EM - 6710 PMID- 5338545 CU - 90 SO - Am J Vet Res 1966 Jul;27(119):1136-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [131 medline neighbors] UI - 66158320 AU - Ball MG TI - Animal hosts of leptospires in Kenya and Uganda. LA - Eng MH - Animal MH - *Antibodies MH - Cattle MH - Disease Reservoirs MH - Dogs MH - Goats MH - Haplorhini MH - In Vitro MH - Kenya MH - Leptospira/*immunology/*isolation & purification MH - Leptospirosis/epidemiology MH - Perissodactyla MH - Rats MH - Rodent Diseases/epidemiology MH - Serodiagnosis MH - Sheep MH - Uganda MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 661002 DP - 1966 Jul IS - 0002-9637 TA - Am J Trop Med Hyg PG - 523-30 SB - A SB - M CY - UNITED STATES IP - 4 VI - 15 JC - 3ZQ EM - 6611 PMID- 4957422 CU - 91 SO - Am J Trop Med Hyg 1966 Jul;15(4):523-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67167893 AU - Horsch F TI - [Leptospiral infection of pigs] LA - Ger MH - Animal MH - Leptospirosis/*veterinary MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 670805 DP - 1966 Jun 15 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 469-74 CY - GERMANY, EAST IP - 12 VI - 21 JC - NGV EM - 6709 PMID- 6007666 CU - 85 TT - Die Leptospireninfektion des Schweines. SO - Monatsh Veterinarmed 1966 Jun 15;21(12):469-74 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [182 medline neighbors] UI - 69267072 AU - Drankin DI AU - Godlevskaia MV TI - [Epidemiologic characteristics of "hay-making" outbreaks of swamp fever] LA - Rus MH - Adolescence MH - Adult MH - Agricultural Workers' Diseases/*epidemiology/etiology MH - Animal MH - Child MH - Child, Preschool MH - Disease Outbreaks/*epidemiology/etiology MH - Disease Reservoirs MH - English Abstract MH - Human MH - Leptospirosis/*epidemiology/etiology MH - Middle Age MH - Rodentia MH - Seasons MH - USSR PT - JOURNAL ARTICLE DA - 691005 DP - 1966 Jun TA - Zh Mikrobiol Epidemiol Immunobiol PG - 63-6 SB - M CY - USSR IP - 6 VI - 43 JC - Y9O EM - 6911 PMID- 6012401 CU - 89 TT - Epidemiologicheskaia kharakteristika "pokosnykh" vspyshek vodnoi likhoradki. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Jun;43(6):63-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69267071 AU - Gorshanova EN TI - [Natural carrier state and humoral immunity in leptospirosis] LA - Rus MH - Animal MH - Carrier State/*epidemiology MH - Cattle MH - Cattle Diseases/*immunology MH - English Abstract MH - Leptospirosis/immunology/*veterinary MH - Swine MH - Swine Diseases/*immunology PT - JOURNAL ARTICLE DA - 691005 DP - 1966 Jun TA - Zh Mikrobiol Epidemiol Immunobiol PG - 59-63 SB - M CY - USSR IP - 6 VI - 43 JC - Y9O EM - 6911 PMID- 6012400 CU - 89 TT - Estestvennoe nositel'stvo i gumoral'nyi immunitet pri leptospirozakh. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Jun;43(6):59-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67132527 AU - Horsch F AU - Schroder HD AU - Graumann H TI - [Leptospira pomona infection in swine] LA - Ger MH - Animal MH - Animals, Newborn MH - Female MH - Germany, East MH - Infertility, Female/etiology MH - Leptospirosis/*veterinary MH - Pregnancy MH - Pregnancy, Animal MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 670616 DP - 1966 Jun 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 418-20 CY - GERMANY, EAST IP - 11 VI - 21 JC - NGV EM - 6708 PMID- 6007211 CU - 85 TT - Leptospira-pomona-Infektion beim Schwein. SO - Monatsh Veterinarmed 1966 Jun 1;21(11):418-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 67127386 AU - Munday BL AU - Ryan FB AU - King SJ AU - Corbould A TI - Preparturient infections and other causes of foetal loss in sheep and cattle in Tasmania. LA - Eng MH - Abnormalities/veterinary MH - Abortion, Veterinary/*etiology MH - Animal MH - Australia MH - Brucellosis, Bovine MH - Cattle MH - Cattle Diseases/*complications MH - Female MH - Goiter/veterinary MH - Leptospirosis/veterinary MH - Listeria Infections/veterinary MH - Liver Diseases/veterinary MH - Mycoses/veterinary MH - Pregnancy MH - Sheep MH - Sheep Diseases/*complications MH - Streptococcal Infections/veterinary MH - Toxoplasmosis, Animal MH - Vibrio PT - JOURNAL ARTICLE DA - 670529 DP - 1966 Jun IS - 0005-0423 TA - Aust Vet J PG - 189-93 SB - M CY - AUSTRALIA IP - 6 VI - 42 JC - 9IE EM - 6707 PMID- 6007038 CU - 85 SO - Aust Vet J 1966 Jun;42(6):189-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 68084328 AU - Silva RM de TI - [Clinical and laboratory study of ictero-hemorrhagic leptospirosis (Weil's disease)] LA - Por MH - Adolescence MH - Adult MH - Brazil MH - Child MH - Diagnosis, Differential MH - Diet Therapy MH - Female MH - Human MH - Male MH - Middle Age MH - Penicillins/therapeutic use MH - Tetracycline/therapeutic use MH - *Weil's Disease PT - JOURNAL ARTICLE DA - 680203 DP - 1966 Jun IS - 0034-7256 TA - Rev Bras Malariol Doencas Trop PG - 281-368 CY - BRAZIL IP - 2 VI - 18 JC - RI9 EM - 6803 PMID- 5987319 TT - Estudo clinico e laboratorial da leptospirose ictero-hemorrhagiae (doenca de Weil) SO - Rev Bras Malariol Doencas Trop 1966 Jun;18(2):281-368 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68046720 AU - Sefer M AU - Dincoulesco M AU - Sulica A TI - [In vitro toxicity of leptospirae on cell cultures] LA - Fre MH - Endotoxins/*pharmacology MH - *Leptospira MH - Tissue Culture PT - JOURNAL ARTICLE DA - 680114 DP - 1966 Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 435-40 CY - ROMANIA IP - 2 VI - 25 JC - 8EM EM - 6802 PMID- 5985364 TT - Toxicite des leptospires sur les cultures cellulaires "in vitro". SO - Arch Roum Pathol Exp Microbiol 1966 Jun;25(2):435-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67217604 AU - Plesko I AU - Hruzik J AU - Janovicova E AU - Sasvari K TI - [On the problem of occupational leptospiroses in employees of the Slovak meat industry] LA - Slo MH - Adolescence MH - Adult MH - Czechoslovakia MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - *Meat-Packing Industry MH - Occupational Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 671020 DP - 1966 Jun TA - Prac Lek PG - 201-6 CY - CZECHOSLOVAKIA IP - 5 VI - 18 JC - PH0 EM - 6711 PMID- 5975428 CU - 89 TT - K problemu profesionalnych leptospiroz zamestnancov masopriemyslu na Slovensku. SO - Prac Lek 1966 Jun;18(5):201-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67172654 AU - Parnas J AU - Cegielka M AU - Cybulska M TI - [Further studies on the antigenic structure of leptospira by electrophoresis and immuno-electrophoresis] LA - Ger MH - Antigens/*analysis MH - Blood Protein Electrophoresis MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 670819 DP - 1966 Jun TA - Zentralbl Veterinarmed [B] PG - 286-96 CY - GERMANY, WEST IP - 3 VI - 13 JC - Y72 EM - 6710 PMID- 5968358 CU - 89 TT - Weitere Forschungen uber die Leptospirenantigen-Struktur mittels Elektrophorese und Immunoelektrophorese. SO - Zentralbl Veterinarmed [B] 1966 Jun;13(3):286-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67124657 AU - Sundharagiati B AU - Kasemsuvan P AU - Harinasuta C AU - Potha U TI - Leptospirosis as a cause of pyrexia of unknown origin in Thailand. LA - Eng MH - Adolescence MH - Adult MH - Child MH - Child, Preschool MH - Female MH - Fever/*etiology MH - Hemagglutination Tests MH - Human MH - Infant MH - Infant, Newborn MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Seasons MH - Thailand PT - JOURNAL ARTICLE DA - 670519 DP - 1966 Jun IS - 0003-4983 TA - Ann Trop Med Parasitol PG - 247-51 SB - M CY - ENGLAND IP - 2 VI - 60 JC - 68E EM - 6707 PMID- 5962475 SO - Ann Trop Med Parasitol 1966 Jun;60(2):247-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66165010 AU - Hamilton JM TI - Nephritis in the cat. LA - Eng MH - Animal MH - Cat Diseases/*etiology MH - Cats MH - Leptospirosis/veterinary MH - Nephritis/*veterinary PT - JOURNAL ARTICLE DA - 661013 DP - 1966 Jun IS - 0022-4510 TA - J Small Anim Pract PG - 445-9 CY - ENGLAND IP - 6 VI - 7 JC - K4N EM - 6612 PMID- 5949696 CU - 85 SO - J Small Anim Pract 1966 Jun;7(6):445-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66160243 AU - Chaudhary RK AU - Fish NA AU - Barnum DA TI - Protection of piglets from immunized sows via colostrum against experimental L. pomona infection. LA - Eng MH - Animal MH - Female MH - Leptospirosis/*immunology/*veterinary MH - Maternal-Fetal Exchange MH - Pregnancy MH - Swine MH - Swine Diseases/*immunology MH - Vaccination PT - JOURNAL ARTICLE DA - 661007 DP - 1966 Jun IS - 0008-5286 TA - Can Vet J PG - 121-7 CY - CANADA IP - 6 VI - 7 JC - CLS EM - 6612 PMID- 5949596 CU - 85 SO - Can Vet J 1966 Jun;7(6):121-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67005017 AU - Urquhart AE AU - Grant LS TI - Leptospirosis in the West Indies--a preliminary survey. LA - Eng MH - Human MH - Leptospirosis/*epidemiology MH - West Indies PT - JOURNAL ARTICLE DA - 661129 DP - 1966 Jun IS - 0043-3144 TA - West Indian Med J PG - 94-6 CY - JAMAICA IP - 2 VI - 15 JC - XN4 EM - 6701 PMID- 5913215 CU - 88 SO - West Indian Med J 1966 Jun;15(2):94-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 67005808 AU - Clapper WE AU - Sanchez A AU - Levy J TI - Immune response to a secondary stimulus with Leptospira canicola and infectious canine hepatitis in beagles exposed to Sr90. LF-29. LA - Eng MH - Animal MH - Antibody Formation/*radiation effects MH - Dogs MH - Hepatitis, Animal/*immunology MH - Leptospira canicola MH - Leptospirosis/*immunology MH - Strontium Isotopes PT - JOURNAL ARTICLE DA - 661130 DP - 1966 Jun TA - Fission Prod Inhal Proj PG - 1-10 CY - UNITED STATES JC - WVE EM - 6701 PMID- 5296567 CU - 89 SO - Fission Prod Inhal Proj 1966 Jun;:1-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [151 medline neighbors] UI - 68100553 AU - Soloshenko IZ AU - Semenova LP TI - [The antibody titer level in animal Leptospira carriers] LA - Rus MH - Animal MH - Antibodies/*analysis MH - Antigen-Antibody Reactions MH - Bacteriological Techniques MH - Cattle MH - *Disease Vectors MH - Leptospirosis/*immunology MH - Sheep MH - Swine PT - JOURNAL ARTICLE DA - 680226 DP - 1966 Jun IS - 0042-4846 TA - Veterinariia PG - 39-40 CY - USSR IP - 6 VI - 43 JC - XCC EM - 6804 PMID- 4865011 CU - 90 TT - Vysota titra antitel u zhivotnykh-leptospironositelei. SO - Veterinariia 1966 Jun;43(6):39-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [142 medline neighbors] UI - 66125624 AU - Hubbert WT AU - Shotts EB TI - Leptospirosis in kennel dogs. LA - Eng MH - Animal MH - Dihydrostreptomycin Sulfate/therapeutic use MH - Dog Diseases/*drug therapy MH - Dogs MH - In Vitro MH - Leptospirosis/*veterinary MH - Oleandomycin/therapeutic use MH - Oxytetracycline/therapeutic use PT - JOURNAL ARTICLE DA - 660723 DP - 1966 May 15 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 1152-9 SB - M CY - UNITED STATES IP - 10 VI - 148 JC - HAV EM - 6609 PMID- 4160355 CU - 95 SO - J Am Vet Med Assoc 1966 May 15;148(10):1152-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66138351 AU - Piolino M AU - Szekely AM TI - [On the pathogenesis of jaundice and renal insufficiency during icterohemorrhagic leptospirosis. (Apropos of the observation of a fatal case)] LA - Fre MH - Aged/etiology MH - Case Report MH - Human MH - Jaundice/*drug effects/*etiology MH - Kidney Failure, Acute/*etiology MH - Male MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 660814 DP - 1966 May 14 IS - 0032-7867 TA - Presse Med PG - 1250-2 SB - M CY - FRANCE IP - 24 VI - 74 JC - PLP EM - 6610 PMID- 5936082 TT - Sur la pathogenie de l'ictere et de l'insuffisance renale au cours de la leptospirose ictero-hemorragique. (A propos de l'observation d'un cas mortel) SO - Presse Med 1966 May 14;74(24):1250-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 69110084 AU - Netsepliaev SV TI - [Duration of carrier state of leptospira in pigs] LA - Rus MH - Animal MH - *Carrier State MH - Hemagglutination Tests MH - Leptospirosis/*blood/urine MH - Swine MH - Swine Diseases/*urine PT - JOURNAL ARTICLE DA - 690328 DP - 1966 May IS - 0042-4846 TA - Veterinariia PG - 29-31 CY - USSR IP - 5 VI - 43 JC - XCC EM - 6905 PMID- 6012246 CU - 85 TT - Dlitel'nost' lepironostiel'stva u svinei. SO - Veterinariia 1966 May;43(5):29-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68315689 TI - Leptospirosis in the Republic of South Africa. LA - Eng MH - Africa, Southern MH - Animal MH - Leptospirosis/*veterinary MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 680823 DP - 1966 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 867-8 CY - FRANCE IP - 1 VI - 66 JC - BR4 EM - 6810 PMID- 6011937 CU - 85 NI - A SO - Bull Off Int Epizoot 1966 May;66(1):867-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68315688 AU - Akkermans JP TI - Incidence of abortion and sterility in swine in the Netherlands due to infection with Leptospira hyos. LA - Eng MH - Abortion, Veterinary/*etiology MH - Animal MH - Female MH - Infertility/*etiology MH - Leptospirosis/*veterinary MH - Male MH - Netherlands MH - Pregnancy MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 680823 DP - 1966 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 849-66 CY - FRANCE IP - 1 VI - 66 JC - BR4 EM - 6810 PMID- 6011936 CU - 85 SO - Bull Off Int Epizoot 1966 May;66(1):849-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68315686 AU - Gaumont R TI - [Study of the presence of ant-leptospira agglutinins in domestic animals in France] LA - Fre MH - Animal MH - Antibodies/*analysis MH - Cattle MH - *Cattle Diseases MH - France MH - *Goats MH - Leptospirosis/veterinary MH - Sheep MH - *Sheep Diseases MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 680823 DP - 1966 May IS - 0300-9823 TA - Bull Off Int Epizoot PG - 833-48 CY - FRANCE IP - 1 VI - 66 JC - BR4 EM - 6810 PMID- 6011934 CU - 85 TT - Enquete sur la presence d'agglutinines antileptospires chez les animaux domestiques en France. SO - Bull Off Int Epizoot 1966 May;66(1):833-48 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67127458 AU - Pigoury L AU - Cottereau P AU - Gaumont R TI - [Bovine leptospirosis. Serological examination of breeding animals destined for export] LA - Fre MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Leptospirosis/diagnosis/*veterinary MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 670529 DP - 1966 May-Jun IS - 0300-9823 TA - Bull Off Int Epizoot PG - 851-70 CY - FRANCE IP - 5 VI - 65 JC - BR4 EM - 6707 PMID- 6007063 CU - 85 TT - La leptospirose bovine controle serologique des reproducteurs destines a l'exportation. SO - Bull Off Int Epizoot 1966 May-Jun;65(5):851-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67127457 AU - Lataste-Dorolle C TI - [Leptospira in animals. Current knowledge in the epizootological category on leptospirosis in France] LA - Fre MH - Animal MH - Cattle MH - Dogs MH - France MH - Human MH - Leptospira/classification/immunology MH - Leptospirosis/*veterinary MH - *Zoonoses PT - JOURNAL ARTICLE DA - 670529 DP - 1966 May-Jun IS - 0300-9823 TA - Bull Off Int Epizoot PG - 831-49 CY - FRANCE IP - 5 VI - 65 JC - BR4 EM - 6707 PMID- 6007062 CU - 85 TT - Le leptospire chez l'animal acquisitions recentes d'ordre epizootologique sur la leptospirose en France. SO - Bull Off Int Epizoot 1966 May-Jun;65(5):831-49 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67129943 AU - Sabattini P TI - [Leptospirosis in the province of Mantua. A statistical and epidemiological study (1954-1963] LA - Ita MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Italy MH - Leptospirosis/*epidemiology/prevention & control MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 670602 DP - 1966 May-Jun IS - 0021-3071 TA - Ann Sanita Pubblica PG - 603-13 CY - ITALY IP - 3 VI - 27 JC - 644 EM - 6707 PMID- 5964033 CU - 88 TT - Le leptospirosi in provincia di Mantova: studio statistico ed epidemiologico (decennio 1954-1963) SO - Ann Sanita Pubblica 1966 May-Jun;27(3):603-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 67121253 AU - Stalheim OH TI - Effects of antimicrobial agents on leptospiral growth, respiration, motility, and viability. LA - Eng MH - Animal MH - Anti-Infective Agents/*pharmacology MH - Antibiotics/*pharmacology MH - Dogs MH - Leptospira/*drug effects/*growth & development/*metabolism MH - Manometry MH - Penicillins/pharmacology MH - Rosaniline Dyes/pharmacology MH - Sulfonamides/pharmacology MH - Tetracycline/pharmacology PT - JOURNAL ARTICLE DA - 670510 DP - 1966 May IS - 0002-9645 TA - Am J Vet Res PG - 797-802 SB - M CY - UNITED STATES IP - 118 VI - 27 JC - 40C EM - 6707 PMID- 5961415 SO - Am J Vet Res 1966 May;27(118):797-802 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [169 medline neighbors] UI - 66125031 AU - Chaudhary RK AU - Fish NA AU - Barnum DA TI - Experimental infection with L. pomona in normal and immune piglets. LA - Eng MH - Animal MH - Freund's Adjuvant MH - In Vitro MH - Leptospirosis/*immunology MH - Swine MH - Swine Diseases/*immunology PT - JOURNAL ARTICLE DA - 660721 DP - 1966 May IS - 0008-5286 TA - Can Vet J PG - 106-12 CY - CANADA IP - 5 VI - 7 JC - CLS EM - 6609 PMID- 5948851 CU - 85 SO - Can Vet J 1966 May;7(5):106-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [147 medline neighbors] UI - 66150765 AU - Philip NA AU - Tennent RB TI - Leptospirosis: a report from one practice on the use of a leptospiral vaccine for a period of three years. LA - Eng MH - Climate MH - Human MH - Immunotherapy/*adverse effects MH - Leptospirosis/*drug therapy/*epidemiology MH - New Zealand MH - Vaccines/*therapeutic use PT - JOURNAL ARTICLE DA - 660917 DP - 1966 May IS - 0028-8446 TA - N Z Med J PG - Suppl 15:13-9 SB - M CY - NEW ZEALAND IP - 405 VI - 65 JC - OBQ EM - 6611 PMID- 5220379 CU - 88 SO - N Z Med J 1966 May;65(405):Suppl 15:13-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [104 medline neighbors] UI - 67121254 AU - Stalheim OH TI - Chemotherapy of renal leptospirosis in hamsters. LA - Eng MH - Animal MH - Antibiotics/*therapeutic use MH - Cephaloridine/therapeutic use MH - Chloramphenicol/therapeutic use MH - Dihydrostreptomycin Sulfate/therapeutic use MH - Erythromycin/therapeutic use MH - Fusidic Acid/therapeutic use MH - Hamsters MH - Kanamycin/therapeutic use MH - Kidney Diseases/*drug therapy MH - Leptospirosis/*drug therapy MH - Lincomycin/therapeutic use MH - Penicillins/therapeutic use MH - Spectinomycin/therapeutic use MH - Tetracycline/therapeutic use PT - JOURNAL ARTICLE DA - 670510 DP - 1966 May IS - 0002-9645 TA - Am J Vet Res PG - 803-7 SB - M CY - UNITED STATES IP - 118 VI - 27 JC - 40C EM - 6707 PMID- 4164020 CU - 95 SO - Am J Vet Res 1966 May;27(118):803-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [129 medline neighbors] UI - 68102450 AU - De Brito T AU - Freymuller E AU - Hoshino S AU - Penna DO TI - Pathology of the kidney and liver in the experimental leptospirosis of the guinea-pig. A light and electron microscopy study. LA - Eng MH - Acid Phosphatase/metabolism MH - Alkaline Phosphatase/metabolism MH - Animal MH - Cytochrome-c Oxidase/metabolism MH - Esterases/metabolism MH - Female MH - Guinea Pigs MH - Kidney/*pathology MH - Leptospira interrogans/*pathogenicity MH - Liver/*pathology MH - Male MH - Microscopy, Electron MH - Succinate Dehydrogenase/metabolism MH - Weil's Disease/enzymology/etiology/*pathology PT - JOURNAL ARTICLE DA - 680302 DP - 1966 Apr 13 TA - Virchows Arch Pathol Anat Physiol Klin Med PG - 64-78 CY - GERMANY, WEST IP - 1 VI - 341 JC - XDG EM - 6804 PMID- 4294883 CU - 93 SO - Virchows Arch Pathol Anat Physiol Klin Med 1966 Apr 13;341(1):64-78 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [164 medline neighbors] UI - 67095386 AU - McClelland R AU - Gillespie JH TI - Canine immunization. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Distemper/immunology MH - Dog Diseases/*immunology/*prevention & control MH - Dogs MH - Hepatitis, Animal/immunology MH - Leptospirosis/immunology MH - Rabies/immunology MH - Rabies Vaccine MH - Vaccination MH - *Viral Vaccines PT - JOURNAL ARTICLE DA - 670418 DP - 1966 Apr IS - 0010-8901 TA - Cornell Vet PG - 300-5 SB - M CY - UNITED STATES IP - 2 VI - 56 JC - DRI EM - 6706 PMID- 6006354 CU - 85 SO - Cornell Vet 1966 Apr;56(2):300-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67095385 AU - Dunne HW TI - The control of pig diseases by immunization. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Erysipeloid/immunology MH - Hog Cholera/immunology MH - Leptospirosis/immunology MH - Swine MH - Swine Diseases/immunology/*prevention & control MH - Vaccination MH - *Viral Vaccines PT - JOURNAL ARTICLE DA - 670418 DP - 1966 Apr IS - 0010-8901 TA - Cornell Vet PG - 293-9 SB - M CY - UNITED STATES IP - 2 VI - 56 JC - DRI EM - 6706 PMID- 6006353 CU - 85 SO - Cornell Vet 1966 Apr;56(2):293-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67096488 AU - Mukherjea AK AU - Sen AK TI - Leptospiral antibodies in random human population in Sikkim. LA - Eng MH - Agglutination Tests MH - *Antibodies MH - Human MH - India MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 670421 DP - 1966 Apr IS - 0068-5372 TA - Bull Calcutta Sch Trop Med PG - 40 CY - INDIA IP - 2 VI - 14 JC - BDS EM - 6706 PMID- 5959887 CU - 88 SO - Bull Calcutta Sch Trop Med 1966 Apr;14(2):40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66120977 AU - Johnson RC AU - Muschel LH TI - Antileptospiral activity of serum. I. Normal and immune serum. LA - Eng MH - Animal MH - Antibodies MH - *Blood MH - Blood Bactericidal Activity MH - Carbon Isotopes MH - Cattle MH - Cell Membrane Permeability MH - *Complement MH - Guinea Pigs MH - Human MH - In Vitro MH - *Leptospira MH - Rabbits MH - Temperature PT - JOURNAL ARTICLE DA - 660714 DP - 1966 Apr IS - 0021-9193 TA - J Bacteriol PG - 1403-9 SB - M CY - UNITED STATES IP - 4 VI - 91 JC - HH3 EM - 6609 PMID- 5929774 SO - J Bacteriol 1966 Apr;91(4):1403-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 66111890 AU - Robert J AU - Turgeon F AU - Lavoie P AU - Cote JR AU - Bernier J AU - Viallet A TI - [A case of icterohemorrhagic leptospirosis. The 6th Canadian case] LA - Fre MH - Case Report MH - Human MH - Male MH - Middle Age MH - *Weil's Disease PT - JOURNAL ARTICLE DA - 660627 DP - 1966 Apr IS - 0041-6959 TA - Union Med Can PG - 408-12 CY - CANADA IP - 4 VI - 95 JC - WNM EM - 6608 PMID- 5910332 TT - Un cas de leptospirose ictero-hemorragique. Sixieme observation Canadienne. SO - Union Med Can 1966 Apr;95(4):408-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66106859 AU - Babudieri B AU - Ghysels G TI - [Study of some strains of Leptospira isolated from hedgehogs (Erinaceus europaeus L.) in Belgium] LA - Fre MH - Animal MH - Belgium MH - In Vitro MH - *Insectivora MH - Leptospira/*classification/*isolation & purification PT - JOURNAL ARTICLE DA - 660619 DP - 1966 Apr IS - 0020-2444 TA - Ann Inst Pasteur (Paris) PG - 627-34 SB - M CY - FRANCE IP - 4 VI - 110 JC - 58Y EM - 6608 PMID- 5908540 TT - Etude de quelques souches de leptospires isolees de herissons (Erinaceus europaeus L.) en Belgique. SO - Ann Inst Pasteur (Paris) 1966 Apr;110(4):627-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [135 medline neighbors] UI - 67096684 AU - Ryu E AU - Liu CK TI - The viability of leptospires in the summer paddy water. LA - Eng MH - Animal MH - Cattle MH - Hydrogen-Ion Concentration MH - Leptospira/*growth & development/isolation & purification/*physiology MH - Seasons MH - Taiwan MH - Temperature MH - *Water Microbiology MH - Zoonoses PT - JOURNAL ARTICLE DA - 670421 DP - 1966 Apr IS - 0021-5139 TA - Jpn J Microbiol PG - 51-7 SB - M CY - JAPAN IP - 1 VI - 10 JC - KMF EM - 6706 PMID- 5297541 CU - 89 SO - Jpn J Microbiol 1966 Apr;10(1):51-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 66109118 AU - Diesch SL AU - McCulloch WF TI - Isolation of pathogenic leptospires from waters used for recreation. LA - Eng MH - Animal MH - Human MH - Iowa MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology MH - *Swimming Pools MH - *Water Microbiology MH - Zoonoses/epidemiology PT - JOURNAL ARTICLE DA - 660621 DP - 1966 Apr IS - 0094-6214 TA - Public Health Rep PG - 299-304 SB - A SB - M CY - UNITED STATES IP - 4 VI - 81 JC - PHR EM - 6608 PMID- 4956096 CU - 91 SO - Public Health Rep 1966 Apr;81(4):299-304 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [37 medline neighbors] UI - 68017320 AU - Pavlov P TI - Studies on some hitherto unknown diseases in Bulgaria with parasitological character in humans and animals. LA - Eng MH - Animal MH - Animal Diseases/epidemiology MH - Arbovirus Infections/*epidemiology MH - Bulgaria MH - Encephalitis, Tick-Borne/epidemiology MH - Hemorrhagic Fevers, Viral/epidemiology MH - Human MH - Keratoconjunctivitis/epidemiology MH - Leishmaniasis/epidemiology MH - Leptospirosis/epidemiology MH - Protozoan Infections/*epidemiology MH - Q Fever/epidemiology MH - Rickettsia Infections/*epidemiology MH - Toxoplasmosis/epidemiology PT - JOURNAL ARTICLE PT - REVIEW DA - 671226 DP - 1966 Apr TA - Zentralbl Bakteriol [Orig] PG - 506-13 SB - M CY - GERMANY, WEST IP - 4 VI - 199 JC - Y4Y EM - 6801 RF - 8 PMID- 4861729 CU - 90 SO - Zentralbl Bakteriol [Orig] 1966 Apr;199(4):506-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [110 medline neighbors] UI - 67095384 AU - Kahrs RF TI - Immunization programs for dairy cattle. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Cattle MH - Cattle Diseases/*immunology MH - Diarrhea/veterinary MH - Dysentery/veterinary MH - Herpesvirus 1, Bovine/immunology MH - Leptospirosis/immunology MH - Mastitis, Bovine/immunology MH - Pasteurella Infections/immunology MH - United States MH - Vaccination MH - *Viral Vaccines PT - JOURNAL ARTICLE DA - 670418 DP - 1966 Apr IS - 0010-8901 TA - Cornell Vet PG - 287-92 SB - M CY - UNITED STATES IP - 2 VI - 56 JC - DRI EM - 6706 PMID- 4289588 CU - 93 SO - Cornell Vet 1966 Apr;56(2):287-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [184 medline neighbors] UI - 69237830 AU - Gol'denshtein ZA TI - [On morbidity with leptospirosis among workers at the Krasnoarmeisk and Maikopsk meat-packing plants] LA - Rus MH - Human MH - Leptospira interrogans MH - Leptospirosis/*epidemiology MH - *Meat-Packing Industry MH - Occupational Diseases/epidemiology MH - Russia PT - JOURNAL ARTICLE DA - 690904 DP - 1966 Apr TA - Zh Mikrobiol Epidemiol Immunobiol PG - 142 SB - M CY - USSR IP - 4 VI - 43 JC - Y9O EM - 6910 PMID- 4240241 CU - 92 TT - O zabolevaemosti leptospirozom rabochikh na Krasnoarmeiskom i Maikopskom miasokombinatakh. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Apr;43(4):142 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 67096507 AU - Payet M AU - Pene P AU - Sankale M AU - Bayet R AU - Bonnardot R AU - Bernou JC AU - Frament V TI - [Leptospirosis in Dakar] LA - Fre MH - Adult MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Senegal PT - JOURNAL ARTICLE DA - 670421 DP - 1966 Mar-Apr IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 207-17 SB - M CY - FRANCE IP - 2 VI - 59 JC - C4G EM - 6706 PMID- 6012836 CU - 88 TT - Les leptospiroses a Dakar. SO - Bull Soc Pathol Exot Filiales 1966 Mar-Apr;59(2):207-17 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 67095110 AU - Rose GW AU - Eveland WC AU - Ellinghausen HC TI - Mechanisms of tissue cell penetration by Leptospira pomona: phagocytosis of leptospires in vitro. LA - Eng MH - Cortisone/pharmacology MH - In Vitro MH - Leptospira/growth & development/immunology/*pathogenicity MH - Opsonins MH - Penicillins/pharmacology MH - *Phagocytosis MH - Streptomycin/pharmacology MH - *Tissue Culture MH - *Virulence PT - JOURNAL ARTICLE DA - 670418 DP - 1966 Mar IS - 0002-9645 TA - Am J Vet Res PG - 503-11 SB - M CY - UNITED STATES IP - 117 VI - 27 JC - 40C EM - 6706 PMID- 5959400 SO - Am J Vet Res 1966 Mar;27(117):503-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66112952 AU - Durham BM TI - Leptospirosis (pomona fever). LA - Eng MH - Adult MH - Animal MH - Case Report MH - Georgia MH - Human MH - *Leptospirosis MH - Male MH - Zoonoses PT - JOURNAL ARTICLE DA - 660628 DP - 1966 Mar IS - 0038-4348 TA - South Med J PG - 272 SB - M CY - UNITED STATES IP - 3 VI - 59 JC - UVH EM - 6608 PMID- 5948729 CU - 85 SO - South Med J 1966 Mar;59(3):272 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [119 medline neighbors] UI - 66134728 AU - Murae M AU - Iwamura N AU - Tada M AU - Takita S AU - Sumida M AU - Ida T AU - Katsuda M TI - A program of prevention and eradication of an endemic disease resembling Weil's disease in Sakaminato City, Tottori Prefecture in Japan. LA - Eng MH - Adult MH - Aged MH - Female MH - Human MH - Japan MH - Leptospirosis/*prevention & control MH - Male MH - Middle Age MH - Weil's Disease/*prevention & control PT - JOURNAL ARTICLE DA - 660731 DP - 1966 Mar IS - 0513-5710 TA - Yonago Acta Med PG - 56-64 CY - JAPAN IP - 1 VI - 10 JC - XRP EM - 6609 PMID- 5934762 SO - Yonago Acta Med 1966 Mar;10(1):56-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66120952 AU - Baseman JB AU - Henneberry RC AU - Cox CD TI - Isolation and growth of Leptospira on artificial media. LA - Eng MH - Culture Media MH - In Vitro MH - Leptospira/*isolation & purification PT - JOURNAL ARTICLE DA - 660714 DP - 1966 Mar IS - 0021-9193 TA - J Bacteriol PG - 1374-5 SB - M CY - UNITED STATES IP - 3 VI - 91 JC - HH3 EM - 6609 PMID- 5929763 SO - J Bacteriol 1966 Mar;91(3):1374-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66112554 AU - Minette HP TI - Leptospirosis in primates other than man. LA - Eng MH - Agglutination Tests MH - Animal MH - *Animal Diseases MH - Antibodies MH - In Vitro MH - Leptospirosis/*epidemiology/immunology MH - *Monkey Diseases MH - *Primates PT - JOURNAL ARTICLE DA - 660628 DP - 1966 Mar IS - 0002-9637 TA - Am J Trop Med Hyg PG - 190-8 SB - A SB - M CY - UNITED STATES IP - 2 VI - 15 JC - 3ZQ EM - 6608 PMID- 5910526 CU - 88 SO - Am J Trop Med Hyg 1966 Mar;15(2):190-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67213106 AU - Sturdza N AU - Safiresco D AU - Ciurea C TI - [Demonstration of leptospirae in unstained smears] LA - Fre MH - Animal MH - *Bacteriological Techniques MH - Guinea Pigs MH - Kidney/microbiology MH - Leptospira/*isolation & purification MH - Mice MH - Rats MH - Swine PT - JOURNAL ARTICLE DA - 671014 DP - 1966 Mar IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 105-10 CY - ROMANIA IP - 1 VI - 25 JC - 8EM EM - 6711 PMID- 5340813 CU - 90 TT - Mise en evidence des leptospires dans des empreintes non-colorees. SO - Arch Roum Pathol Exp Microbiol 1966 Mar;25(1):105-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66133030 AU - Rostomyan SV TI - Antagonistic relationships between leptospiras of different serological types. LA - Eng MH - Agglutination MH - In Vitro MH - Leptospira/*immunology MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology PT - JOURNAL ARTICLE DA - 660731 DP - 1966 Mar-Apr TA - Fed Proc Transl Suppl PG - 341-3 CY - UNITED STATES IP - 2 VI - 25 JC - EUY EM - 6609 PMID- 5219773 CU - 89 SO - Fed Proc Transl Suppl 1966 Mar-Apr;25(2):341-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68125754 AU - Anan'in VV AU - Semenova LP TI - [Changes in the serological and antigenic properties of pathogenic leptospira under experimental conditions. 1.] LA - Rus MH - Animal MH - *Antigens MH - Bacteriological Techniques MH - Culture Media MH - Hemagglutination Tests MH - Leptospira/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 680404 DP - 1966 Mar TA - Zh Mikrobiol Epidemiol Immunobiol PG - 34-9 SB - M CY - USSR IP - 3 VI - 43 JC - Y9O EM - 6805 PMID- 4865887 CU - 90 TT - Izmenenie serologicheskikh i antigennykh svoistv patogennykh leptospir v eksperimente. 1. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Mar;43(3):34-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68192442 AU - Petrova KF TI - [On the epizootiology of leptospirosis in Dagestan] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases MH - Dog Diseases MH - Dogs MH - Horse Diseases MH - Horses MH - Leptospirosis/epidemiology/*veterinary MH - Russia MH - Swine MH - Swine Diseases PT - JOURNAL ARTICLE DA - 680523 DP - 1966 Mar IS - 0042-4846 TA - Veterinariia PG - 47-9 CY - USSR IP - 3 VI - 43 JC - XCC EM - 6807 RO - M:CNR PMID- 4230672 LR - 880125 CU - 92 TT - K epizootologii leptospiroza v Dagestane. SO - Veterinariia 1966 Mar;43(3):47-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 68043663 AU - Parnas J AU - Cegielka M AU - Cybulska M TI - [Immunochemical studies on the antigen structure of leptospira] LA - Ger MH - Absorption MH - Alpha-Globulins/analysis MH - Animal MH - Antigens/*analysis MH - Beta-Globulins/analysis MH - Blood Protein Electrophoresis MH - Chromatography MH - Gamma-Globulins/analysis MH - Immune Sera/*analysis MH - Immunoelectrophoresis MH - Leptospira/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 680112 DP - 1966 Mar TA - Zentralbl Bakteriol [Orig] PG - 360-79 SB - M CY - GERMANY, WEST IP - 3 VI - 199 JC - Y4Y EM - 6802 PMID- 4168211 CU - 95 TT - Immunochemische Untersuchungen uber die Antigen-Struktur der Leptospiren. SO - Zentralbl Bakteriol [Orig] 1966 Mar;199(3):360-79 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67041616 AU - Diesch SL AU - McCulloch WF AU - Braun JL AU - Ellinghausen HC Jr TI - Leptospires isolated from frog kidneys. LA - Eng MH - Animal MH - Anura MH - Kidney/*microbiology MH - Leptospira/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 670123 DP - 1966 Feb 26 IS - 0028-0836 TA - Nature PG - 939-40 SB - M CY - ENGLAND IP - 26 VI - 209 JC - NSC EM - 6703 PMID- 5922807 SO - Nature 1966 Feb 26;209(26):939-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68043579 AU - Liubashenko SIa AU - Netseplyaev SV AU - Kostrikina LG AU - Loginov IA TI - [New data on the etiology and epizootiology of leptospirosis in animals] LA - Rus MH - Animal MH - Cattle MH - *Cattle Diseases MH - *Horse Diseases MH - Horses MH - Leptospirosis/microbiology/*veterinary MH - Serology MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 680112 DP - 1966 Feb IS - 0042-4846 TA - Veterinariia PG - 34-7 CY - USSR IP - 2 VI - 43 JC - XCC EM - 6802 PMID- 6010667 CU - 85 TT - Novye dannye po etiologii i epizootologii leptospiroza zhivotnykh. SO - Veterinariia 1966 Feb;43(2):34-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69252963 AU - Kiktenko VS AU - Troshin KA TI - [A study of the morhology of leptosira by the electron microscope method] LA - Rus MH - Cell Membrane MH - Cytoplasm MH - English Abstract MH - *Leptospira MH - Leptospira interrogans MH - Microscopy, Electron PT - JOURNAL ARTICLE DA - 690919 DP - 1966 Feb TA - Zh Mikrobiol Epidemiol Immunobiol PG - 85-90 SB - M CY - USSR IP - 2 VI - 43 JC - Y9O EM - 6911 PMID- 6004858 CU - 89 TT - Izuchenie morfologii leptospir metodom elektronnoi mikroskopii. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Feb;43(2):85-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67097001 AU - Battistini A TI - [Uveitis due to Leptospira. (Clinical contribution)] LA - Ita MH - Adult MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Serodiagnosis MH - Uveitis/*etiology PT - JOURNAL ARTICLE DA - 670422 DP - 1966 Feb IS - 0003-4665 TA - Ann Ottalmol Clin Ocul PG - 77-83 CY - ITALY IP - 2 VI - 92 JC - 5RA EM - 6706 PMID- 5960096 TT - Le uveiti da Leptospire. (Contributo clinico) SO - Ann Ottalmol Clin Ocul 1966 Feb;92(2):77-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66159063 AU - Fiocre B AU - Lataste Dorolle C TI - [Bovine and equine leptospirosis at the farms of Cher and Loiret in the spring of 1965. Isolation of strains belonging to Grippotyphosa serologic group] LA - Fre MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - France MH - Horse Diseases/*epidemiology MH - Horses MH - In Vitro MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 661002 DP - 1966 Feb IS - 0001-4192 TA - Bull Acad Vet Fr PG - 69-77 CY - FRANCE IP - 2 VI - 39 JC - BA8 EM - 6611 PMID- 5949578 CU - 88 TT - Leptospirose bovine et equine dans les fermes du Cher et du Loiret au cours du printemps 1965. Isolement de souches appartenant au groupe serologique Grippotyphosa. SO - Bull Acad Vet Fr 1966 Feb;39(2):69-77 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66107753 AU - Fennestad KL AU - Borg-Petersen C TI - Experimental leptospirosis in pregnant sows. LA - Eng MH - Animal MH - Animals, Newborn MH - Female MH - Fetal Death MH - Leptospira interrogans MH - Leptospirosis/*physiopathology MH - Pregnancy MH - *Pregnancy Complications, Infectious MH - *Pregnancy, Animal MH - Swine PT - JOURNAL ARTICLE DA - 660619 DP - 1966 Feb IS - 0022-1899 TA - J Infect Dis PG - 57-66 SB - A SB - M CY - UNITED STATES IP - 1 VI - 116 JC - IH3 EM - 6608 PMID- 5948605 CU - 85 SO - J Infect Dis 1966 Feb;116(1):57-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69252930 AU - Pomanskaia LZ TI - [On an antigen for the complement fixation test in leptospirosis] LA - Rus MH - Agglutination Tests MH - *Antigens MH - Clinical Trials MH - Comparative Study MH - *Complement Fixation Tests MH - Female MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*diagnosis MH - Species Specificity PT - CLINICAL TRIAL PT - JOURNAL ARTICLE DA - 690919 DP - 1966 Feb TA - Zh Mikrobiol Epidemiol Immunobiol PG - 128 SB - M CY - USSR IP - 2 VI - 43 JC - Y9O EM - 6911 PMID- 4894984 CU - 90 TT - Ob antigene dlia reaktsii sviazyvaniia komplementa na listerioz. SO - Zh Mikrobiol Epidemiol Immunobiol 1966 Feb;43(2):128 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 71117640 AU - Lakatos M TI - [Experience with studies on leptospirosis] LA - Hun PT - JOURNAL ARTICLE DA - 710407 DP - 1966 Jan 23 IS - 0030-6002 TA - Orv Hetil PG - 163-5 CY - HUNGARY IP - 4 VI - 107 JC - OL8 EM - 7105 PMID- 6015277 TT - Leptospirosissal kapcsolatos vizsgalatok tapaszialatai. SO - Orv Hetil 1966 Jan 23;107(4):163-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 66100284 AU - Willis MF AU - Wannan JS TI - Some aspects of the epidemiology of leptospirosis in New Guinea. LA - Eng MH - Human MH - Leptospirosis/*epidemiology MH - New Guinea PT - JOURNAL ARTICLE DA - 660525 DP - 1966 Jan 22 IS - 0025-729X TA - Med J Aust PG - 129-36 SB - M CY - AUSTRALIA IP - 4 VI - 1 JC - M26 EM - 6607 PMID- 5906931 CU - 88 SO - Med J Aust 1966 Jan 22;1(4):129-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [120 medline neighbors] UI - 69051826 AU - Samostrel'skii AIu TI - [A study of certain problems of experimental leptospiral infections with the use of radioisotope indicators] LA - Rus MH - Adrenal Glands/microbiology MH - Animal MH - *Autoradiography MH - Blood/microbiology MH - Bone Marrow/microbiology MH - Guinea Pigs MH - Heart/microbiology MH - Kidney/microbiology MH - Leptospirosis/*diagnosis/microbiology/pathology MH - Liver/microbiology MH - Lymph Nodes/microbiology MH - Muscles/microbiology MH - *Phosphorus Isotopes MH - Spleen/microbiology MH - Urine/microbiology PT - JOURNAL ARTICLE DA - 690117 DP - 1966 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 76-85 CY - USSR VI - 29 JC - VZR EM - 6903 PMID- 6015039 CU - 89 TT - Izuchenie nekotorykh voprosov eksperimental'noi leptospiroznoi infektsii s primeneniem radioizotopnykh indikatorov. SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1966;29:76-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69051822 AU - Tokarevich KN AU - Popova EM AU - Pupkevich-Diamant IaS TI - [On the problem of fever reaction of the organism in leptospirosis infection. 1. Fever reaction in icterohemorrhagic leptospirosis] LA - Rus MH - Abortion/etiology MH - Adolescence MH - Adult MH - Body Temperature MH - Eye Manifestations MH - Female MH - Fever/*physiopathology MH - Human MH - Male MH - Middle Age MH - Neuritis/etiology MH - Parotitis/etiology MH - Pneumonia/etiology MH - Pregnancy MH - Psychotic Disorders/etiology MH - Time Factors MH - Weil's Disease/complications/*physiopathology PT - JOURNAL ARTICLE DA - 690117 DP - 1966 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 44-63 CY - USSR VI - 29 JC - VZR EM - 6903 PMID- 6015037 CU - 90 TT - K voprosu o likhoradochnoi reaktsii organizma pri leptospiroznoi infektsii. 1. Likhoradochnaia reaktsiia pri ikterogemorragicheskom leptospiroze. SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1966;29:44-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67098462 AU - Ioli A AU - Mattace-Raso G AU - Tredici E TI - [On the incidence of leptospiral infections in cattle and swine in the Province of Catanzaro] LA - Ita MH - Animal MH - Cattle MH - Cattle Diseases/*microbiology MH - Italy MH - Leptospirosis/*veterinary MH - Swine MH - Swine Diseases/*microbiology PT - JOURNAL ARTICLE DA - 670426 DP - 1966 Jan-Apr IS - 0035-6921 TA - Riv Ital Ig PG - 107-12 CY - ITALY IP - 1 VI - 26 JC - TLD EM - 6706 PMID- 6006582 CU - 85 TT - Sulla frequenza di infezioni da leptospire in un gruppo di bovini e di suini della Provincia di Catanzaro. SO - Riv Ital Ig 1966 Jan-Apr;26(1):107-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 70284953 AU - Mello MT de AU - Mello AM de TI - [Serologic microtechnic diagnosis of plague, brucellosis and leptospirosis] LA - Spa MH - Agglutination Tests MH - Animal MH - Antigen-Antibody Reactions MH - Brucellosis/*immunology/veterinary MH - Human MH - Leptospirosis/*immunology/veterinary MH - Marsupialia/immunology MH - Methods MH - Microchemistry MH - Plague/*immunology/veterinary MH - Rodentia/immunology MH - *Serodiagnosis PT - JOURNAL ARTICLE DA - 701028 DP - 1966-67 IS - 0485-1854 TA - An Microbiol (Rio J) PG - 63-76 CY - BRAZIL VI - 14 JC - 4JA EM - 7012 RO - M:CNR PMID- 6005633 LR - 910604 CU - 90 TT - Microtecnicas serologicas para el diagnostico de peste, brucelosis y leptospirosis. SO - An Microbiol (Rio J) 1966-67;14:63-76 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 68287968 AU - Addamiano L TI - [Antibiotics in the therapy of leptospirosis] LA - Ita MH - Antibiotics/*therapeutic use MH - Human MH - Leptospirosis/*drug therapy MH - Weil's Disease/*drug therapy PT - JOURNAL ARTICLE DA - 680808 DP - 1966 TA - Rass Clin Ter PG - 324-30 CY - ITALY IP - 6 VI - 65 JC - QSX EM - 6809 PMID- 5997960 CU - 89 TT - Gli antibiotici nella terapia delle leptospirosi. SO - Rass Clin Ter 1966;65(6):324-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68270811 AU - Lazuga K TI - [Analysis of receptors of Leptospira strains isolated in South-East Poland] LA - Pol MH - Agglutination Tests MH - Antigens/*analysis MH - Human MH - Leptospira/*immunology/isolation & purification MH - Leptospirosis/*epidemiology MH - Poland PT - JOURNAL ARTICLE DA - 680717 DP - 1966 IS - 0066-2240 TA - Ann Univ Mariae Curie Sklodowska [Med] PG - 149-66 CY - POLAND VI - 21 JC - 69M EM - 6809 PMID- 5996248 CU - 88 TT - Analiza receptorow szczepow leptospir wyizolowanych w poludniowo- wschodniej Polsce. SO - Ann Univ Mariae Curie Sklodowska [Med] 1966;21:149-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 68128647 AU - Bravo C AU - Restrepo ROBLEDO M AU - Perez G TI - [Leptospirosis in Antioquia. Preliminary communication] LA - Spa MH - Colombia MH - Human MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 680408 DP - 1966 TA - Antioquia Med PG - 543-4 CY - COLOMBIA IP - 6 VI - 16 JC - 6I6 EM - 6805 PMID- 5990130 CU - 89 TT - Leptospirosis en Antioquia. Comunicacion preliminar. SO - Antioquia Med 1966;16(6):543-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68056010 AU - Resende M AU - Costa CA AU - Lobao A AU - Melo GB TI - [1st cases of leptospirosis diagnosed serologically in Belem (Para- Brazil)] LA - Por MH - Adult MH - Brazil MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 680122 DP - 1966 Jan-Jun TA - An Inst Med Trop (Lisb) PG - 245-7 CY - PORTUGAL IP - 1 VI - 23 JC - 4FM EM - 6802 PMID- 5986689 CU - 89 TT - Primeiros casos de leptospirose diagnosticados sorologicamente em Belem (Para-Brasil) SO - An Inst Med Trop (Lisb) 1966 Jan-Jun;23(1):245-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [197 medline neighbors] UI - 68009489 AU - Babudieri B TI - [The systematic position of the serotype Budapest strain of Leptospira] LA - Ger MH - Leptospira interrogans/*classification PT - JOURNAL ARTICLE DA - 671216 DP - 1966 Jan TA - Zentralbl Bakteriol [Orig] PG - 67-71 SB - M CY - GERMANY, WEST IP - 1 VI - 199 JC - Y4Y EM - 6801 PMID- 5983109 CU - 89 TT - Die systematische Stellung des "Serotyp Budapest" der Leptospira. SO - Zentralbl Bakteriol [Orig] 1966 Jan;199(1):67-71 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67100391 AU - Mukherjea AK AU - Mukherji A AU - Sen AK TI - Leptospiral antibodies in random human population in Calcutta. LA - Eng MH - Adolescence MH - Adult MH - *Antibodies MH - Child MH - Female MH - Human MH - India MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology MH - Male PT - JOURNAL ARTICLE DA - 670504 DP - 1966 Jan IS - 0068-5372 TA - Bull Calcutta Sch Trop Med PG - 7-8 CY - INDIA IP - 1 VI - 14 JC - BDS EM - 6706 PMID- 5961045 CU - 88 SO - Bull Calcutta Sch Trop Med 1966 Jan;14(1):7-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67060446 AU - Chorvath B TI - [Incorporation of the ammonia ion by Leptospira in Korthof's medium] LA - Slo MH - Ammonia/*metabolism MH - Culture Media MH - In Vitro MH - Leptospira/*metabolism PT - JOURNAL ARTICLE DA - 670309 DP - 1966 IS - 0006-3088 TA - Biologia (Bratisl) PG - 602-5 CY - CZECHOSLOVAKIA IP - 8 VI - 21 JC - A4G EM - 6704 PMID- 5955577 TT - Inkorporacia amonioveho ionu leptospirami v Korthofovej pode. SO - Biologia (Bratisl) 1966;21(8):602-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67059059 AU - Hupka S AU - Oravec C AU - Kmety E TI - A study concerning the distribution of 51Cr-labelled leptospirae in various organs of guinea-pigs with Daels' sarcoma. LA - Eng MH - Animal MH - Chromium Isotopes/diagnostic use MH - Guinea Pigs MH - Kidney/*analysis MH - *Leptospira/*analysis MH - Liver/*analysis MH - Lung/*analysis MH - Muscles/*analysis MH - *Sarcoma, Experimental MH - Spleen/*analysis PT - JOURNAL ARTICLE DA - 670307 DP - 1966 IS - 0028-2685 TA - Neoplasma PG - 565-72 SB - M CY - CZECHOSLOVAKIA IP - 5 VI - 13 JC - NVO EM - 6704 PMID- 5955063 SO - Neoplasma 1966;13(5):565-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67056625 AU - Petrov RV AU - Manyko VM AU - Zhabina MI AU - Sidorovich IG TI - Antibody formation by spleen cells from mice of inbred strains genetically differing in their capacity for antibody formation. LA - Eng MH - Animal MH - *Antibody Formation MH - Antigen-Antibody Reactions MH - Genetics MH - Immunization MH - In Vitro MH - Leptospira/*immunology MH - Mice MH - Spleen/*cytology PT - JOURNAL ARTICLE DA - 670304 DP - 1966 IS - 0015-5500 TA - Folia Biol (Praha) PG - 442-51 SB - M CY - CZECHOSLOVAKIA IP - 6 VI - 12 JC - EYH EM - 6704 PMID- 5954143 SO - Folia Biol (Praha) 1966;12(6):442-51 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66092072 AU - Correa MO AU - Hyakutake S AU - Natale V AU - Galvao PA AU - Aguiar H de A TI - Preliminary note about occurrence of Leptospira wolffii in Sao Paulo, Brazil. LA - Eng MH - Brazil MH - Graves' Disease/*etiology MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 660520 DP - 1966 Jan-Feb IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 53-4 CY - BRAZIL IP - 1 VI - 8 JC - S9D EM - 6607 PMID- 5951955 CU - 88 SO - Rev Inst Med Trop Sao Paulo 1966 Jan-Feb;8(1):53-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [172 medline neighbors] UI - 67048257 AU - Yanagihara Y TI - [Pathogenic Leptospirae. 3. Growth of Leptospira icterohaemorrhagiae in media containing Mycobacterium smegmatis cultured for various days] LA - Jpn MH - Culture Media MH - Leptospira interrogans/*growth & development MH - *Mycobacterium PT - JOURNAL ARTICLE DA - 670205 DP - 1966 Jan 1 IS - 0019-1604 TA - Igaku To Seibutsugaku PG - 5-7 CY - JAPAN IP - 1 VI - 72 JC - LPA EM - 6703 PMID- 5951271 CU - 85 SO - Igaku To Seibutsugaku 1966 Jan 1;72(1):5-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67018313 AU - Sundharagiati B AU - Boonpacknavig S AU - Harinasuta C AU - Pholpothi T TI - Seasonal incidence of canine leptospirosis in Bangkok. LA - Eng MH - Agglutination Tests MH - Animal MH - Dog Diseases/*epidemiology MH - Dogs MH - Leptospirosis/*epidemiology/*veterinary MH - Seasons MH - Thailand PT - JOURNAL ARTICLE DA - 661230 DP - 1966 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 366-8 SB - M CY - ENGLAND IP - 3 VI - 60 JC - WBU EM - 6702 PMID- 5950686 CU - 88 SO - Trans R Soc Trop Med Hyg 1966;60(3):366-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67018312 AU - Sundharagiati B AU - Harinasuta C AU - Photha U TI - Human leptospirosis in Thailand. LA - Eng MH - Adult MH - Agglutination Tests MH - Animal MH - Centrifugation MH - Female MH - Human MH - Hydrogen-Ion Concentration MH - Leptospira/classification/pathogenicity MH - Leptospirosis/*epidemiology MH - Male MH - Mice MH - Middle Age MH - Occupations MH - Rats MH - Thailand MH - Water Microbiology PT - JOURNAL ARTICLE DA - 661230 DP - 1966 IS - 0035-9203 TA - Trans R Soc Trop Med Hyg PG - 361-5 SB - M CY - ENGLAND IP - 3 VI - 60 JC - WBU EM - 6702 PMID- 5950685 CU - 88 SO - Trans R Soc Trop Med Hyg 1966;60(3):361-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66165872 AU - Sturdza N AU - Safiresco D TI - [Reservoirs of leptospires in Rumania] LA - Fre MH - Animal MH - Cats MH - Cattle MH - Disease Reservoirs MH - Dogs MH - Human MH - In Vitro MH - Leptospirosis/*veterinary MH - Rats MH - Romania PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 251-7 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5949709 CU - 85 TT - Reservoirs de leptospires en Roumanie. SO - Ann Soc Belg Med Trop 1966;46(2):251-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66165863 AU - Altava V TI - [Epizootics and epidemiology of leptospirosis of murine origin in a rural milieu. Prevention] LA - Spa MH - Animal MH - Disease Reservoirs MH - Human MH - Leptospirosis/*epidemiology/*prevention & control MH - *Rodentia MH - Spain PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 161-70 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5949708 CU - 88 TT - Epizootia y epidemiologia de las leptospirosis de origen murino en el medio agricola Profilaxis. SO - Ann Soc Belg Med Trop 1966;46(2):161-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 66165862 AU - Mitov A AU - Jankov N AU - Ivanov I TI - [The reservoirs of leptospires in the rice-field region of south Bulgaria] LA - Fre MH - Animal MH - Bulgaria MH - Disease Reservoirs MH - Human MH - Leptospira/*isolation & purification MH - Mice MH - *Rodentia PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 155-9 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5949707 CU - 85 TT - Les reservoirs des leptospires dans la region des rizieres en Bulgarie du sud. SO - Ann Soc Belg Med Trop 1966;46(2):155-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66165861 AU - Fraga de Azevedo J TI - [ON THE EPIDEMIOLOGY OF LEPTOSPIROSIS IN Portugal] LA - Fre MH - Adolescence MH - Adult MH - Aged MH - Animal MH - Cats MH - Cattle MH - Child MH - Child, Preschool MH - Dogs MH - Human MH - In Vitro MH - Infant MH - Infant, Newborn MH - Leptospirosis/*veterinary MH - Middle Age MH - Portugal MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 135-54 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5949706 CU - 88 TT - Sur l'epidemiologie et l'epizootiologie des leptospiroses au Portugal. SO - Ann Soc Belg Med Trop 1966;46(2):135-54 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 66075559 TI - Quarantine. LA - Eng MH - Animal MH - Cattle MH - Leptospirosis/*prevention & control MH - *Quarantine PT - JOURNAL ARTICLE DA - 660409 DP - 1966 Jan IS - 0007-1935 TA - Br Vet J PG - 38-9 CY - ENGLAND IP - 1 VI - 122 JC - B5C EM - 6606 PMID- 5948166 CU - 85 NI - A SO - Br Vet J 1966 Jan;122(1):38-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66169227 AU - Bakoss P TI - [Contribution to the variability of the antigenic structure of leptospires] LA - Fre MH - *Antigens MH - In Vitro MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 97-102 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5945749 TT - Contribution a la variabilite de la structure antigenique des leptospires. SO - Ann Soc Belg Med Trop 1966;46(1):97-102 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66169226 AU - Ananyin VV AU - Semyonova LP TI - Variability of the serological and antigenic properties of pathogenic leptospires in experimental conditions. LA - Eng MH - Antigen-Antibody Reactions MH - In Vitro MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 85-96 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5945748 SO - Ann Soc Belg Med Trop 1966;46(1):85-96 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [179 medline neighbors] UI - 66169225 AU - Van Riel J AU - Van Riel M TI - [Biological cycle of leptospires] LA - Fre MH - In Vitro MH - Leptospira/*growth & development PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 71-84 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5945747 TT - Cycle biologique des leptospires. SO - Ann Soc Belg Med Trop 1966;46(1):71-84 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66169224 AU - Ryter A AU - Lataste-Dorolle C TI - [Study with the electron microscope of the "agglutination-lysis" reaction] LA - Fre MH - Animal MH - *Antigen-Antibody Reactions MH - Human MH - In Vitro MH - Leptospira/*immunology MH - Microscopy, Electron MH - Rabbits PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 55-69 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5945746 TT - Etude au microscope electronique de la reaction "d'agglutination-lyse". SO - Ann Soc Belg Med Trop 1966;46(1):55-69 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66169222 AU - Borg-Petersen C TI - Remarks on the philosophy underlying the presently accepted classification of Leptospires. LA - Eng MH - In Vitro MH - Leptospira/*classification PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 29-40 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5945745 SO - Ann Soc Belg Med Trop 1966;46(1):29-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66169221 AU - Turner LH TI - Taxonomy and nomenclature of leptospira. General considerations. LA - Eng MH - In Vitro MH - Leptospira/*classification MH - *Nomenclature PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 23-7 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5945744 SO - Ann Soc Belg Med Trop 1966;46(1):23-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66169219 AU - Wolff JW AU - Bohlander HJ TI - Evaluation of Galton's macroscopic slide test for the serodiagnosis of leptospirosis in human serum samples. LA - Eng MH - *Hemagglutination Tests MH - Human MH - In Vitro MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 123-33 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5945743 SO - Ann Soc Belg Med Trop 1966;46(1):123-33 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66169217 AU - Kmety E TI - Main antigens as criterion for differentiating leptospiral serotypes. LA - Eng MH - *Antigens MH - In Vitro MH - Leptospira/*classification PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 103-10 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5945742 SO - Ann Soc Belg Med Trop 1966;46(1):103-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66165873 AU - Sefer M TI - [On the antigen structure and endotoxins of leptospires. A preliminary report)] LA - Ger MH - *Antigens MH - *Endotoxins MH - In Vitro MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 259-66 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5944013 TT - Uber Antigenstruktur und Endotoxine der Leptospiren. (Vorlaufige Mitteilung) SO - Ann Soc Belg Med Trop 1966;46(2):259-66 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [148 medline neighbors] UI - 66165869 AU - Kemenes F TI - Leptospira icterohaemorrhagiae-infection of experimental animals with artificially decreased resistance. LA - Eng MH - Animal MH - Cats MH - Cattle MH - Dogs MH - Ethionine/*pharmacology MH - Guinea Pigs MH - Human MH - In Vitro MH - Mice MH - Rabbits MH - *Radiation Effects MH - Rats MH - Weil's Disease/*immunology PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 235-44 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5944012 SO - Ann Soc Belg Med Trop 1966;46(2):235-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66165868 AU - Plesko I TI - Criteria of postvaccinal immunity in leptospirosis. LA - Eng MH - Animal MH - *Bacterial Vaccines MH - Comparative Study MH - Human MH - Immunity MH - In Vitro MH - Leptospirosis/*immunology MH - Rabbits MH - Vaccination PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 225-34 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5944011 SO - Ann Soc Belg Med Trop 1966;46(2):225-34 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66165867 AU - Gsell O TI - [Treatment of leptospirosis] LA - Fre MH - Adult MH - Case Report MH - Female MH - Human MH - Leptospirosis/*drug therapy MH - Male MH - Penicillins/*therapeutic use MH - Tetracycline/*therapeutic use PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 203-12 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5944010 TT - Le traitement des leptospiroses. SO - Ann Soc Belg Med Trop 1966;46(2):203-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66165866 AU - Cox CD TI - Studies on the isolation and growth of Leptospira from surface waters. LA - Eng MH - Culture Media MH - In Vitro MH - Leptospira/*isolation & purification MH - United States MH - *Water Microbiology PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 193-202 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5944009 SO - Ann Soc Belg Med Trop 1966;46(2):193-202 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 66165865 AU - Addamiano L AU - Papa J TI - Leptospirae enzymatic properties on phospholipids. LA - Eng MH - In Vitro MH - Leptospira/*enzymology MH - *Lipase MH - *Phospholipases MH - *Phospholipids PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 187-91 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5944008 SO - Ann Soc Belg Med Trop 1966;46(2):187-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 66165864 AU - Brouwers J TI - [Leptospiral nephritis in dogs] LA - Fre MH - Animal MH - Dogs MH - In Vitro MH - Leptospira canicola/*pathogenicity MH - Leptospira interrogans/*pathogenicity MH - Leptospirosis/*veterinary MH - Nephritis/*veterinary PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 177-86 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5944007 TT - La nephrite leptospirienne du chien. SO - Ann Soc Belg Med Trop 1966;46(2):177-86 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 67049185 AU - Bobrowski H TI - [Clinical and therapeutical remarks on the participation of the kidneys in acute infectious diseases] LA - Pol MH - Human MH - Kidney/*physiopathology MH - Kidney Diseases/etiology MH - Leptospirosis/*physiopathology MH - Respiratory Tract Infections/physiopathology PT - JOURNAL ARTICLE DA - 670205 DP - 1966 IS - 0033-2100 TA - Przegl Epidemiol PG - 331-5 CY - POLAND IP - 3 VI - 20 JC - Q8T EM - 6703 PMID- 5926511 TT - Uwagi kliniczno-terapeutyczne na marginesie udzialu nerek w ostrych chorobach zakaznych. SO - Przegl Epidemiol 1966;20(3):331-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67049177 AU - Migdalska-Kassurowa B AU - Kossakiewicz B TI - [Marsh fever (leptospirosis grippotyphosa)] LA - Pol MH - Adult MH - Diagnosis, Differential MH - Human MH - Leptospirosis/*diagnosis/epidemiology MH - Male MH - Middle Age MH - Poland MH - Typhoid/diagnosis MH - Typhus, Epidemic Louse-Borne/diagnosis PT - JOURNAL ARTICLE DA - 670205 DP - 1966 IS - 0033-2100 TA - Przegl Epidemiol PG - 293-8 CY - POLAND IP - 3 VI - 20 JC - Q8T EM - 6703 PMID- 5926503 CU - 88 TT - Goraczka blotna (leptospirosis grippotyphosa) SO - Przegl Epidemiol 1966;20(3):293-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67004632 AU - Harrington DD AU - Sleight SD TI - Leptospira pomona in tissue culture: preliminary study. LA - Eng MH - Acid-Base Equilibrium MH - Animal MH - Cattle MH - Kidney/cytology MH - Leptospira/cytology/growth & development/*pathogenicity MH - Temperature MH - *Tissue Culture MH - Toxins/biosynthesis PT - JOURNAL ARTICLE DA - 661129 DP - 1966 Jan IS - 0002-9645 TA - Am J Vet Res PG - 249-56 SB - M CY - UNITED STATES IP - 116 VI - 27 JC - 40C EM - 6701 PMID- 5913031 SO - Am J Vet Res 1966 Jan;27(116):249-56 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66071844 AU - Gale NB AU - Alexander AD AU - Evans LB AU - Yager RH AU - Matheney RG TI - An outbreak of leptospirosis among U. S. army troops in the Canal Zone. LA - Eng MH - Agglutination Tests MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology MH - *Military Medicine MH - Panama MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 660327 DP - 1966 Jan IS - 0002-9637 TA - Am J Trop Med Hyg PG - 64-70 SB - A SB - M CY - UNITED STATES IP - 1 VI - 15 JC - 3ZQ EM - 6605 PMID- 5902111 CU - 88 SO - Am J Trop Med Hyg 1966 Jan;15(1):64-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66068514 AU - Mackenzie RB AU - Reiley CG AU - Alexander AD AU - Bruckner EA AU - Diercks FH AU - Beye HK TI - An outbreak of leptospirosis among U. S. army troops in the Canal Zone. LA - Eng MH - Agglutination Tests MH - Antigen-Antibody Reactions MH - Disease Reservoirs MH - Human MH - Leptospirosis/*epidemiology MH - *Military Medicine MH - Panama PT - JOURNAL ARTICLE DA - 660318 DP - 1966 Jan IS - 0002-9637 TA - Am J Trop Med Hyg PG - 57-63 SB - A SB - M CY - UNITED STATES IP - 1 VI - 15 JC - 3ZQ EM - 6605 PMID- 5901631 CU - 88 SO - Am J Trop Med Hyg 1966 Jan;15(1):57-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66173095 AU - Resseler R AU - Van Riel M AU - Van Riel J TI - [Preservation of leptospires after cooling or lyophilization] LA - Fre MH - *Bacteriological Techniques MH - *Freeze Drying MH - In Vitro MH - *Leptospira PT - JOURNAL ARTICLE DA - 661023 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 213-24 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5329930 CU - 90 TT - Conservation des leptospires apres refroidissement ou lyophilisation. SO - Ann Soc Belg Med Trop 1966;46(2):213-24 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 66169228 AU - Van Riel J TI - [International Colloquim on Leptospirosis. Introduction] LA - Fre MH - Animal MH - Guinea Pigs MH - History of Medicine, 19th Cent. MH - History of Medicine, 20th Cent. MH - Human MH - In Vitro MH - Leptospirosis/*history MH - Rats MH - Weil's Disease/*history PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 9-14 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5329575 CU - 90 TT - Colloque International sur la Leptospirose. Introduction. SO - Ann Soc Belg Med Trop 1966;46(1):9-14 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66169220 AU - Abdussalam M TI - International work in leptospirosis. LA - Eng MH - Bibliography MH - History of Medicine, 20th Cent. MH - *International Cooperation MH - *Leptospirosis PT - BIBLIOGRAPHY PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 15-21 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5329574 CU - 90 SO - Ann Soc Belg Med Trop 1966;46(1):15-21 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66169218 AU - Kmety E AU - Plesko I AU - Bakoss P AU - Chorvath B TI - Evaluation of methods for differentiating pathogenic and saprophytic leptospira strains. LA - Eng MH - Animal MH - *Bacteriological Techniques MH - In Vitro MH - Leptospira/*classification MH - Mice MH - Rabbits PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 111-22 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 5329573 CU - 90 SO - Ann Soc Belg Med Trop 1966;46(1):111-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66165871 AU - Czekalowski JW AU - Singh SP TI - Can leptospirae divide longitudinally? LA - Eng MH - Bacteriological Techniques MH - In Vitro MH - Leptospira/*growth & development PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 249-50 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5329313 CU - 90 SO - Ann Soc Belg Med Trop 1966;46(2):249-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66165870 AU - Czekalowski JW AU - Singh SP TI - Fixation of leptospirae for thin sectioning. LA - Eng MH - *Bacteriological Techniques MH - In Vitro MH - *Leptospira PT - JOURNAL ARTICLE DA - 661014 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 245-8 CY - BELGIUM IP - 2 VI - 46 JC - 66K EM - 6612 PMID- 5329312 CU - 90 SO - Ann Soc Belg Med Trop 1966;46(2):245-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [82 medline neighbors] UI - 66097011 AU - Siefert G TI - [Spirochaeta antigens] LA - Ger MH - Antigens MH - Borrelia MH - In Vitro MH - Leptospira MH - Spirochaeta/*immunology MH - Treponema pallidum PT - JOURNAL ARTICLE PT - REVIEW DA - 660522 DP - 1966 TA - Ergeb Mikrobiol Immunitatsforsch Exp Ther PG - 14-42 CY - GERMANY, WEST VI - 39 JC - ELF EM - 6607 RF - 97 RO - M:BDS PMID- 5324496 LR - 860807 CU - 90 TT - Spirochaten-Antigene. SO - Ergeb Mikrobiol Immunitatsforsch Exp Ther 1966;39:14-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [133 medline neighbors] UI - 67045494 AU - Torten M AU - Beemer AM AU - Hoeden J van der TI - Physaloptera clausa, a possible new reservoir host for parasitic leptospires. LA - Eng MH - Animal MH - *Disease Reservoirs MH - *Insectivora MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 670130 DP - 1966 IS - 0042-9686 TA - Bull World Health Organ PG - 278-9 CY - SWITZERLAND IP - 2 VI - 35 JC - C80 EM - 6703 PMID- 5297011 CU - 89 SO - Bull World Health Organ 1966;35(2):278-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [204 medline neighbors] UI - 67213296 AU - Mitov A AU - Ljubenov I TI - Leptospirosis mini in South Bulgaria. LA - Eng MH - Bulgaria MH - Human MH - Leptospira/*isolation & purification MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 671014 DP - 1966 IS - 0204-8043 TA - Folia Med (Plovdiv) PG - 206-10 CY - BULGARIA IP - 4 VI - 8 JC - F19 EM - 6711 PMID- 4962375 CU - 91 SO - Folia Med (Plovdiv) 1966;8(4):206-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [30 medline neighbors] UI - 67122034 AU - Parnas J AU - Hencner Z AU - Pleszczynska E AU - Poplawski S AU - Cybulska M TI - Comparison of biotypes, serotypes, chemotypes and spectrophotometric infrared types of Brucellae, Klebsiellae, Listeriae, Erysipelothrix and Leptospirae. LA - Eng MH - Brucella/*classification MH - Erysipelothrix/*classification MH - Klebsiella/*classification MH - Leptospira/*classification MH - Listeria monocytogenes/*classification PT - JOURNAL ARTICLE DA - 670512 DP - 1966 IS - 0001-4087 TA - Bull Acad Pol Sci [Biol] PG - 475-81 CY - POLAND IP - 7 VI - 14 JC - B8W EM - 6707 PMID- 4960177 CU - 91 SO - Bull Acad Pol Sci [Biol] 1966;14(7):475-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [167 medline neighbors] UI - 69051825 AU - Samostrel'skii AIu AU - Matveev OG TI - [Experience in obtaining labeled (radioactive) cultures of leptospira] LA - Rus MH - Animal MH - *Bacteriological Techniques MH - Culture Media MH - Leptospira/*growth & development MH - *Phosphorus Isotopes MH - Swine PT - JOURNAL ARTICLE DA - 690117 DP - 1966 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 70-5 CY - USSR VI - 29 JC - VZR EM - 6903 PMID- 4881111 CU - 90 TT - Opyt polucheniia mechenykh (radioaktivnykh) kul'tur leptospir. SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1966;29:70-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 69051821 AU - Popova EM AU - Sil'ianova VI AU - Iachmenev NI TI - [Canicola leptospirosis in the Northwestern USSR] LA - Rus MH - Adolescence MH - Adult MH - Agriculture MH - Animal MH - Disease Reservoirs MH - Dogs MH - Female MH - Fever MH - Human MH - Immune Sera MH - Leptospira canicola/growth & development MH - *Leptospirosis MH - Male MH - Middle Age MH - Occupational Diseases MH - Rabbits MH - Rodentia MH - Russia MH - Serotyping MH - Swine MH - Time Factors PT - JOURNAL ARTICLE DA - 690117 DP - 1966 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 36-43 CY - USSR VI - 29 JC - VZR EM - 6903 PMID- 4235447 CU - 92 TT - Leptospiroz kanikola na severo-zapade SSSR. SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1966;29:36-43 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 69051820 AU - Popova EM AU - Fedoseeva MF AU - Serebriakov GA AU - Bazhenova AA AU - Kopytkin SI TI - [Data on natural foci of leptospirosis in Pskov District] LA - Rus MH - Adult MH - Animal MH - Animals, Domestic MH - Child MH - Disease Reservoirs MH - Human MH - Leptospirosis/diagnosis/*epidemiology/etiology MH - Rodentia MH - Russia MH - Serodiagnosis MH - Serotyping MH - Weil's Disease/diagnosis MH - Zoonoses PT - JOURNAL ARTICLE DA - 690117 DP - 1966 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 29-35 CY - USSR VI - 29 JC - VZR EM - 6903 PMID- 4235446 CU - 92 TT - Materialy o prirodnoi ochagovosti leptospirozov v Pskovskoi oblasti. SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1966;29:29-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [116 medline neighbors] UI - 69051814 AU - Tokarevich KN AU - Timofeeva SS AU - Popova EM AU - Ikonnikov NS AU - Sosnitskii VM TI - [On the epidemiology of leptospirosis in the Arkhangel'sk District] LA - Rus MH - Adult MH - Animal MH - Cattle MH - Deer MH - Disease Reservoirs/microbiology MH - Human MH - Leptospirosis/diagnosis/*epidemiology/etiology MH - Mass Screening/veterinary MH - Mice MH - Rats MH - Rodentia MH - Russia MH - Swine MH - Water Pollution MH - Zoonoses PT - JOURNAL ARTICLE DA - 690117 DP - 1966 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 21-8 CY - USSR VI - 29 JC - VZR EM - 6903 PMID- 4235445 CU - 92 TT - K epidemiologii leptospirozov v Arkhangel'skoi oblasti. SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1966;29:21-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [165 medline neighbors] UI - 69051803 AU - Tokarevich KN AU - Popova EM TI - [Leptospirosis among children in the Northwest USSR (epidemiological and clinical data)] LA - Rus MH - Adolescence MH - Child MH - Child, Preschool MH - Female MH - Fever MH - Human MH - Jaundice MH - Leptospirosis/*epidemiology MH - Male MH - Meningitis/epidemiology MH - Russia MH - Seasons MH - Sex Factors MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 690117 DP - 1966 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 14-20 CY - USSR VI - 29 JC - VZR EM - 6903 PMID- 4235442 CU - 92 TT - Leptospirozy u detei na severo-zapade SSSR (epidemiologicheskie i klinicheskie materialy) SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1966;29:14-20 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 69051824 AU - Lesnikov AL AU - Popova EM TI - [Experience in the use of specific gamma globulin in the treatment of leptospiroses] LA - Rus MH - Adolescence MH - Adult MH - Animal MH - Antibiotics/therapeutic use MH - Fever MH - Gamma-Globulins/*therapeutic use MH - Human MH - Leptospirosis/complications/*therapy MH - Meningitis/etiology MH - Middle Age MH - *Occupational Diseases MH - Pneumonia/etiology MH - Swine MH - Weil's Disease/complications/*therapy PT - JOURNAL ARTICLE DA - 690117 DP - 1966 TA - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol PG - 64-9 CY - USSR VI - 29 JC - VZR EM - 6903 PMID- 4177537 CU - 95 TT - Opyt primeneniia spetsificheskogo gamma-globulina dlia lecheniia leptospirozov. SO - Tr Leningr Nauchnoissled Inst Epidemiol Mikrobiol 1966;29:64-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [188 medline neighbors] UI - 69010124 AU - Tarasevich NN AU - Mitrofanov VG TI - [Complement fixation with dry antigen as a method f of serodiagnosis of leptospirosis] LA - Rus MH - *Antigens MH - Clinical Trials MH - *Complement Fixation Tests MH - Human MH - Leptospirosis/*diagnosis MH - Methods MH - Serodiagnosis PT - CLINICAL TRIAL PT - JOURNAL ARTICLE DA - 681204 DP - 1966 IS - 0023-6748 TA - Lab Delo PG - 488-90 CY - USSR VI - 8 JC - KYU EM - 6901 PMID- 4176247 CU - 95 TT - Reaktsiia sviazyvaniia komplementa s sukhim antigenom kak metod serodiagnostiki leptospirozov. SO - Lab Delo 1966;8:488-90 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [171 medline neighbors] UI - 69010123 AU - Ternovskaia LN TI - [On the possibilities of using synthetic nutrient media for growing Leptospira. I. Consumption by Leptospira of free amino acids from the nutrient medium during the process of growth] LA - Rus MH - Amino Acids/*metabolism MH - *Culture Media MH - Leptospira/*growth & development/metabolism PT - JOURNAL ARTICLE DA - 681204 DP - 1966 IS - 0023-6748 TA - Lab Delo PG - 487-8 CY - USSR VI - 8 JC - KYU EM - 6901 PMID- 4176246 CU - 95 TT - O vozmozhnosti ispol'zovaniia sinteticheskikh pitatel'nykh sred dlia vyrashchivaniia leptospir. I. Potreblenie leptospirami v protsesse rosta svobodnykh aminokislot iz pitatel'noi sredy. SO - Lab Delo 1966;8:487-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [181 medline neighbors] UI - 68091551 AU - Samostrel'skii AIu TI - [A method of direct counting of Leptospira in a given volume] LA - Rus MH - Bacteriological Techniques MH - *Leptospira MH - *Microscopy PT - JOURNAL ARTICLE DA - 680215 DP - 1966 IS - 0023-6748 TA - Lab Delo PG - 105-9 CY - USSR VI - 2 JC - KYU EM - 6803 PMID- 4169288 CU - 95 TT - Metod priamogo scheta leptospir v opredelennom ob''eme. SO - Lab Delo 1966;2:105-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 66169223 AU - Czekalowski JW AU - Singh SP TI - Staining of sectioned leptospirae with heavy metals. LA - Eng MH - In Vitro MH - *Leptospira MH - Photomicrography MH - *Staining PT - JOURNAL ARTICLE DA - 661016 DP - 1966 IS - 0037-9638 TA - Ann Soc Belg Med Trop PG - 41-53 CY - BELGIUM IP - 1 VI - 46 JC - 66K EM - 6612 PMID- 4161532 CU - 95 SO - Ann Soc Belg Med Trop 1966;46(1):41-53 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66076605 AU - Graf HT TI - An investigation into the status of leptospirosis in Rhodesia. LA - Eng MH - Animal MH - Cattle MH - Dogs MH - Human MH - Leptospirosis/*diagnosis/*epidemiology MH - Rats MH - Zimbabwe PT - JOURNAL ARTICLE DA - 660409 DP - 1965 Dec IS - 0008-9176 TA - Cent Afr J Med PG - 363-6 CY - ZIMBABWE IP - 12 VI - 11 JC - CQO EM - 6606 PMID- 5892849 CU - 88 SO - Cent Afr J Med 1965 Dec;11(12):363-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66046011 AU - Allen V AU - Sueltmann S AU - Evans AS TI - Leptospirosis in Wisconsin. LA - Eng MH - Agglutination Tests MH - Human MH - In Vitro MH - Leptospirosis/*epidemiology MH - Occupational Diseases/*diagnosis MH - Serodiagnosis MH - Wisconsin PT - JOURNAL ARTICLE DA - 660210 DP - 1965 Dec IS - 0002-9572 TA - Am J Public Health Nations Health PG - 1936-44 SB - A SB - M CY - UNITED STATES IP - 12 VI - 55 JC - AJP EM - 6604 PMID- 5891894 CU - 88 SO - Am J Public Health Nations Health 1965 Dec;55(12):1936-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66142054 AU - Torten M AU - Shenberg E AU - Hoeden J van der TI - The role of birds in the epidemiology of leptospirosis. LA - Eng MH - Agglutination Tests MH - Animal MH - *Birds MH - Disease Vectors MH - In Vitro MH - Israel MH - Leptospira/*immunology MH - Leptospirosis/*epidemiology MH - Mice PT - JOURNAL ARTICLE DA - 660825 DP - 1965 Dec IS - 0041-3232 TA - Trop Geogr Med PG - 353-8 SB - M CY - NETHERLANDS IP - 4 VI - 17 JC - WGJ EM - 6610 PMID- 5884328 CU - 88 SO - Trop Geogr Med 1965 Dec;17(4):353-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66080239 AU - Spradbrow PB TI - Experimental Leptospira australis infection in calves. LA - Eng MH - Animal MH - Cattle MH - *Cattle Diseases MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 660417 DP - 1965 Dec IS - 0005-0423 TA - Aust Vet J PG - 391-3 SB - M CY - AUSTRALIA IP - 12 VI - 41 JC - 9IE EM - 6606 PMID- 5858849 SO - Aust Vet J 1965 Dec;41(12):391-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 66079912 AU - Pike RM AU - McBrayer HL AU - Schulze ML AU - Chandler CH TI - Chromatographic analysis and sulfhydryl sensitivity of antileptospira agglutinins in rabbit and human sera. LA - Eng MH - Animal MH - *Antibodies MH - Chromatography MH - Human MH - In Vitro MH - Leptospira canicola/immunology MH - Leptospira interrogans/immunology MH - Leptospirosis/*immunology MH - *Mercaptoethanol MH - Rabbits PT - JOURNAL ARTICLE DA - 660415 DP - 1965 Dec IS - 0037-9727 TA - Proc Soc Exp Biol Med PG - 786-9 SB - M CY - UNITED STATES IP - 3 VI - 120 JC - PXZ EM - 6606 PMID- 5858706 SO - Proc Soc Exp Biol Med 1965 Dec;120(3):786-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 66034880 AU - Diaz Rivera RS TI - The clinical aspects of the leptospiroses. LA - Eng MH - Human MH - *Leptospirosis MH - Weil's Disease PT - JOURNAL ARTICLE DA - 660115 DP - 1965 Dec IS - 0023-0294 TA - J Ky Med Assoc PG - 952-9 CY - UNITED STATES IP - 12 VI - 63 JC - IV8 EM - 6603 PMID- 5839520 SO - J Ky Med Assoc 1965 Dec;63(12):952-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 67133880 AU - Mochmann H TI - [50 Years of pathogenic leptospirae. A look back on the history of their discovery] LA - Ger MH - Bacteriology/*history MH - Germany MH - History of Medicine MH - History of Medicine, 19th Cent. MH - History of Medicine, 20th Cent. MH - Japan MH - *Leptospira MH - Weil's Disease PT - HISTORICAL ARTICLE PT - JOURNAL ARTICLE DA - 670619 DP - 1965 Dec TA - Zentralbl Bakteriol [Orig] PG - 137-42 SB - M CY - GERMANY, WEST IP - 1 VI - 198 JC - Y4Y EM - 6708 PMID- 5336927 CU - 90 TT - /) Jahre pathogene Leptospiren Ein Ruckblick auf die Geschichte ihrer Entdeckung. SO - Zentralbl Bakteriol [Orig] 1965 Dec;198(1):137-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 66166088 AU - Yanagihara Y AU - Mifuchi I TI - Studies on pathogenic leptospirae. IV. GROWTH OF Leptospira icterohaemorrhagiae by replacing rabbit serum with Reiter treoneme cells. LA - Eng MH - Culture Media MH - In Vitro MH - Leptospira interrogans/*growth & development MH - *Treponema PT - JOURNAL ARTICLE DA - 661014 DP - 1965 Dec IS - 0021-5139 TA - Jpn J Microbiol PG - 161-6 SB - M CY - JAPAN IP - 4 VI - 9 JC - KMF EM - 6612 PMID- 5296327 CU - 89 SO - Jpn J Microbiol 1965 Dec;9(4):161-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66050585 AU - Sartaj AU - Ahluwalia S AU - Alberts JO AU - Hanson LE TI - Effect of cortisone on Leptospira pomona infection in guinea pig. LA - Eng MH - Animal MH - Cortisone/pharmacology MH - Guinea Pigs MH - *Leptospirosis PT - JOURNAL ARTICLE DA - 660219 DP - 1965 Nov IS - 0019-6479 TA - Indian Vet J PG - 837-48 CY - INDIA IP - 11 VI - 42 JC - GM9 EM - 6604 PMID- 5848746 SO - Indian Vet J 1965 Nov;42(11):837-48 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66045269 AU - Hocker ND AU - Bauer DC TI - The nature of antibodies synthesized during the immune response to Leptospira biflexa. LA - Eng MH - Animal MH - Antibodies/*biosynthesis MH - *Antibody Formation MH - Antigens/administration & dosage MH - IgG/biosynthesis MH - Immunochemistry MH - Leptospira/*immunology MH - Macroglobulins/biosynthesis MH - Mercaptoethanol MH - Rabbits MH - Ultracentrifugation PT - JOURNAL ARTICLE DA - 660209 DP - 1965 Nov IS - 0022-1767 TA - J Immunol PG - 887-94 SB - A SB - M CY - UNITED STATES IP - 5 VI - 95 JC - IFB EM - 6604 PMID- 5845875 SO - J Immunol 1965 Nov;95(5):887-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [207 medline neighbors] UI - 66013390 AU - Baker HJ TI - Leptospirosis in Malaysia. LA - Eng MH - Animal MH - Leptospirosis/*epidemiology MH - Malaysia PT - JOURNAL ARTICLE DA - 651211 DP - 1965 Nov IS - 0026-4075 TA - Mil Med PG - 1101-2 CY - UNITED STATES IP - 11 VI - 130 JC - N1A EM - 6602 PMID- 4953542 CU - 91 SO - Mil Med 1965 Nov;130(11):1101-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67096909 AU - Mezhennyi AM TI - [The result of animal inspection for leptospirosis] LA - Rus MH - Animal MH - Byelarus MH - Cattle MH - Cattle Diseases/*epidemiology MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/*veterinary MH - Sheep MH - Sheep Diseases/*epidemiology MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 670421 DP - 1965 Nov IS - 0042-4846 TA - Veterinariia PG - 39-40 CY - USSR IP - 11 VI - 42 JC - XCC EM - 6706 PMID- 4225295 CU - 92 TT - Rezul'tat obsledovaniia zhivotnykh na leptospiroz. SO - Veterinariia 1965 Nov;42(11):39-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67096908 AU - Maliavin AG AU - Solov'eva VS AU - Shupliko AN TI - [Specific activity of polyvalent leptospirosis vaccine] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*prevention & control MH - Leptospirosis/*veterinary MH - Rabbits MH - Russia MH - Swine MH - Swine Diseases/*prevention & control MH - Vaccination/veterinary PT - JOURNAL ARTICLE DA - 670421 DP - 1965 Nov IS - 0042-4846 TA - Veterinariia PG - 37-9 CY - USSR IP - 11 VI - 42 JC - XCC EM - 6706 PMID- 4225294 CU - 92 TT - Spetsificheskaia aktivnost' polivalentnoi leptospiroznoi vaktsiny. SO - Veterinariia 1965 Nov;42(11):37-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 66069482 AU - Laroche V TI - [Human leptospirosis in Haiti] LA - Spa MH - Adolescence MH - Adult MH - Child MH - Female MH - Haiti MH - Hemagglutination Tests MH - Human MH - In Vitro MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 660319 DP - 1965 Nov IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 414-22 CY - UNITED STATES IP - 5 VI - 59 JC - AGG EM - 6605 PMID- 4221579 CU - 92 TT - La leptospirose humaine en Haiti. SO - Bol Oficina Sanit Panam 1965 Nov;59(5):414-22 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [61 medline neighbors] UI - 66011557 AU - Ryu E TI - Serum fractions inhibitory to the growth of Leptospires. LA - Eng MH - Animal MH - Blood MH - Cattle MH - Culture Media MH - In Vitro MH - Leptospira/*growth & development MH - Leptospira canicola/growth & development MH - Leptospira interrogans/growth & development MH - Pasteurella/growth & development MH - Poultry MH - Serum Albumin/*pharmacology MH - Serum Albumin, Bovine/pharmacology MH - Serum Globulins/*pharmacology MH - Swine PT - JOURNAL ARTICLE DA - 651208 DP - 1965 Nov IS - 0316-5957 TA - Can J Comp Med Vet Sci PG - 279-82 SB - M CY - CANADA IP - 11 VI - 29 JC - BCY EM - 6602 PMID- 4220645 CU - 92 SO - Can J Comp Med Vet Sci 1965 Nov;29(11):279-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66014228 AU - Heath CW Jr AU - Alexander AD AU - Galton MM TI - Leptospirosis in the United States. Analysis of 483 cases in man, 1949, 1961. LA - Eng MH - Human MH - In Vitro MH - Leptospirosis/*diagnosis/*epidemiology MH - United States PT - JOURNAL ARTICLE PT - REVIEW DA - 651213 DP - 1965 Oct 21 IS - 0028-4793 TA - N Engl J Med PG - 915-22 concl SB - A SB - M CY - UNITED STATES IP - 17 VI - 273 JC - NOW EM - 6602 RF - 20 PMID- 5319290 CU - 90 SO - N Engl J Med 1965 Oct 21;273(17):915-22 concl ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66003505 AU - Gsell O TI - [Therapy of leptospirosis] LA - Ger MH - Human MH - Leptospirosis/*drug therapy MH - Penicillins/*therapeutic use PT - JOURNAL ARTICLE DA - 651120 DP - 1965 Oct 15 IS - 0012-0472 TA - Dtsch Med Wochenschr PG - 1870-2 SB - M CY - GERMANY, WEST IP - 42 VI - 90 JC - ECL EM - 6601 PMID- 5826950 TT - Die Therapie der Leptospirosen. SO - Dtsch Med Wochenschr 1965 Oct 15;90(42):1870-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 66001551 AU - Heath CW Jr AU - Alexander AD AU - Galton MM TI - Leptospirosis in the United States. LA - Eng MH - Adolescence MH - Adult MH - Aged MH - Child MH - Child, Preschool MH - Female MH - Human MH - Infant MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - United States PT - JOURNAL ARTICLE PT - REVIEW DA - 651114 DP - 1965 Oct 14 IS - 0028-4793 TA - N Engl J Med PG - 857-64 contd SB - A SB - M CY - UNITED STATES IP - 16 VI - 273 JC - NOW EM - 6601 RF - 70 PMID- 5317985 CU - 90 SO - N Engl J Med 1965 Oct 14;273(16):857-64 contd ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [141 medline neighbors] UI - 68324356 AU - Fujikura T TI - Studies on the lethal susceptibility of laboratory mice to Leptospira icterohaemorrhagiae. LA - Eng MH - Animal MH - Leptospira interrogans/*pathogenicity MH - *Leptospirosis MH - *Mice/radiation effects MH - Neutralization Tests MH - Virulence PT - JOURNAL ARTICLE DA - 680905 DP - 1965 Oct IS - 0021-5295 TA - Nippon Juigaku Zasshi PG - 283-7 CY - JAPAN IP - 5 VI - 27 JC - KRJ EM - 6810 PMID- 5896601 CU - 85 SO - Nippon Juigaku Zasshi 1965 Oct;27(5):283-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67085246 AU - Markiavichus A AU - Chapas B TI - [Leptospirosis in animals in the Lithuanian SSR] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Horse Diseases/*epidemiology MH - Horses MH - Leptospirosis/*veterinary MH - Lithuania MH - Swine MH - Swine Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 670325 DP - 1965 Oct IS - 0042-4846 TA - Veterinariia PG - 32-4 CY - USSR IP - 10 VI - 42 JC - XCC EM - 6705 PMID- 5896046 CU - 88 TT - Leptospiroz zhivotnykh v Litovskoi SSR. SO - Veterinariia 1965 Oct;42(10):32-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66156073 AU - Mailloux M TI - [On the sources of infection with leptospires in North Africa] LA - Fre MH - Africa, Northern MH - Animal MH - Human MH - Leptospirosis/*epidemiology MH - Rats MH - Rodent Control MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 660930 DP - 1965 Oct TA - Z Tropenmed Parasitol PG - 291-6 SB - M CY - GERMANY, WEST IP - 3 VI - 16 JC - Y12 EM - 6611 PMID- 5894791 CU - 89 TT - Sur les sources de contamination par les leptospires en Afrique du Nord. SO - Z Tropenmed Parasitol 1965 Oct;16(3):291-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66101407 AU - Horsch F TI - [On the role of Leptospira infections in abortions among swine in the northern districts of the German Democratic Republic] LA - Ger MH - Abortion, Veterinary/*etiology MH - Animal MH - Female MH - Germany, East MH - Leptospirosis/*complications MH - Pregnancy MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 660526 DP - 1965 Oct 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 806-11 CY - GERMANY, EAST IP - 19 VI - 20 JC - NGV EM - 6607 PMID- 5893518 CU - 85 TT - Zur Rolle von Leptospireninfektionen bei Aborten in einigen Zuchtschweinebestanden der Nordbezirke der DDR. SO - Monatsh Veterinarmed 1965 Oct 1;20(19):806-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [88 medline neighbors] UI - 66044740 AU - Annear DI TI - Recoveries of Strigomonas oncopelti, Leptospirae and Reiter's treponeme from desiccates after storage for five years. LA - Eng MH - In Vitro MH - *Leptospira MH - Preservation, Biological MH - *Protozoa MH - *Treponema PT - JOURNAL ARTICLE DA - 660209 DP - 1965 Oct IS - 0004-945X TA - Aust J Exp Biol Med Sci PG - 683-4 SB - M CY - AUSTRALIA IP - 5 VI - 43 JC - 9FW EM - 6604 PMID- 5845600 SO - Aust J Exp Biol Med Sci 1965 Oct;43(5):683-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66037463 AU - Hubbert WT AU - Miller JN TI - Studies on immunity in experimental leptospirosis: the immunogenicity of Leptospira icterohemorrhagiae attenuated by gamma-irradiation. LA - Eng MH - Agglutination Tests MH - Animal MH - Antigens MH - Guinea Pigs MH - Immunity MH - Leptospira interrogans/*immunology MH - Leptospirosis/*immunology MH - *Radiation Effects PT - JOURNAL ARTICLE DA - 660120 DP - 1965 Oct IS - 0022-1767 TA - J Immunol PG - 759-64 SB - A SB - M CY - UNITED STATES IP - 4 VI - 95 JC - IFB EM - 6603 PMID- 5841058 SO - J Immunol 1965 Oct;95(4):759-64 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 66005671 AU - McGowan JE AU - Karstad L TI - Field and laboratory studies of skunks, raccoons and groundhogs as reservoirs of Leptospira pomona. LA - Eng MH - Animal MH - Canada MH - *Carnivora MH - In Vitro MH - *Leptospira MH - Leptospirosis/*epidemiology MH - Rodent Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 651120 DP - 1965 Oct IS - 0008-5286 TA - Can Vet J PG - 243-52 CY - CANADA IP - 10 VI - 6 JC - CLS EM - 6601 PMID- 5828180 CU - 88 SO - Can Vet J 1965 Oct;6(10):243-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66005433 AU - Philip RN AU - Casper EA AU - Stoenner HG AU - Lackman DB AU - McGreevey JE TI - Leptospirosis among abattoir workers in Montana. LA - Eng MH - *Abattoirs MH - Adult MH - Aged MH - Antibodies MH - Human MH - Leptospirosis/*epidemiology MH - Montana PT - JOURNAL ARTICLE DA - 651120 DP - 1965 Oct IS - 0035-760X TA - Rocky Mt Med J PG - 51-4 passim CY - UNITED STATES IP - 10 VI - 62 JC - TWX EM - 6601 PMID- 5828028 CU - 88 SO - Rocky Mt Med J 1965 Oct;62(10):51-4 passim ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67047118 AU - Anan'in VV AU - Kokovin IL AU - Novitskaia VI TI - [Retrospective serological examination of the population in leptospirosis foci] LA - Rus MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*epidemiology MH - Middle Age MH - Retrospective Studies MH - Russia PT - JOURNAL ARTICLE DA - 670205 DP - 1965 Oct TA - Zh Mikrobiol Epidemiol Immunobiol PG - 136-7 SB - M CY - USSR IP - 10 VI - 42 JC - Y9O EM - 6703 PMID- 4224379 CU - 92 TT - Opyt retrospektivnogo serologicheskogo obsledovaniia naseleniia v ochagakh leptospirozov. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Oct;42(10):136-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [206 medline neighbors] UI - 66036271 AU - Gajda A TI - [Leptospirosis] LA - Pol MH - Adolescence MH - Adult MH - Female MH - Human MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - Poland MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 660115 DP - 1965 Sep 27 IS - 0032-3756 TA - Pol Tyg Lek PG - 1455-7 CY - POLAND IP - 39 VI - 20 JC - PBY EM - 6603 PMID- 5840325 CU - 88 TT - Leptospirozy. SO - Pol Tyg Lek 1965 Sep 27;20(39):1455-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [173 medline neighbors] UI - 66067259 AU - Beyers CP TI - Serological and cultural evidence of leptospirae in Cape Town dogs. LA - Eng MH - Animal MH - Carrier State MH - *Dogs MH - *Leptospira canicola MH - *Leptospira interrogans MH - South Africa PT - JOURNAL ARTICLE DA - 660312 DP - 1965 Sep 25 IS - 0038-2469 TA - S Afr Med J PG - 797-8 SB - M CY - SOUTH AFRICA IP - 35 VI - 39 JC - U4R EM - 6605 PMID- 5853121 SO - S Afr Med J 1965 Sep 25;39(35):797-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66093213 AU - Libor J AU - Ivanyi J TI - [On the problem of leptospirosis in Hungary] LA - Ger MH - Adolescence MH - Adult MH - Child MH - Female MH - Human MH - Hungary MH - Legislation, Medical MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age MH - *Occupational Diseases MH - Weil's Disease/*epidemiology PT - JOURNAL ARTICLE DA - 660521 DP - 1965 Sep 17 IS - 0025-8458 TA - Med Klin PG - 1530-2 SB - M CY - GERMANY, WEST IP - 38 VI - 60 JC - M4E EM - 6607 PMID- 5861902 CU - 88 TT - Zur Frage der Leptospirosen un Ungarn. SO - Med Klin 1965 Sep 17;60(38):1530-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 67013509 AU - Mailloux M TI - [Leptospiroses in Morocco: further data] LA - Fre MH - Animal MH - Human MH - Leptospirosis/*epidemiology MH - Morocco MH - Rats PT - JOURNAL ARTICLE DA - 661223 DP - 1965 Sep-Oct IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 841-7 SB - M CY - FRANCE IP - 5 VI - 58 JC - C4G EM - 6702 PMID- 5899555 CU - 88 TT - Les leptospiroses au Maroc: nouveaux documents. SO - Bull Soc Pathol Exot Filiales 1965 Sep-Oct;58(5):841-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67050053 AU - Iurkov GG AU - Andriian EA AU - Voloshchuk LG TI - [Study of experimental leptospirosis in swine] LA - Rus MH - Animal MH - Hemagglutination Tests MH - Leptospirosis/immunology/*veterinary MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 670208 DP - 1965 Sep IS - 0042-4846 TA - Veterinariia PG - 33-5 CY - USSR IP - 9 VI - 42 JC - XCC EM - 6703 PMID- 5895854 CU - 85 TT - Isuchenie eksperimental'nogo leptospiroza svinei. SO - Veterinariia 1965 Sep;42(9):33-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67050052 AU - Selivanov AV AU - Butuzov GM AU - Tiagunina EA TI - [On passive immunity against leptospirosis in piglets] LA - Rus MH - Animal MH - *Immunity, Maternally-Acquired MH - Leptospirosis/immunology/*veterinary MH - Swine MH - Swine Diseases/*immunology PT - JOURNAL ARTICLE DA - 670208 DP - 1965 Sep IS - 0042-4846 TA - Veterinariia PG - 31-3 CY - USSR IP - 9 VI - 42 JC - XCC EM - 6703 PMID- 5895853 CU - 85 TT - O passivnom immunitete protiv leptospiroza u porosiat. SO - Veterinariia 1965 Sep;42(9):31-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67050051 AU - Sosov RF AU - Kovba PIa TI - [On the etiologic and epidemiologic significance of leptospira of the L. hebdomadis serogroup] LA - Rus MH - Animal MH - Cattle MH - Cattle Diseases/*immunology MH - Hemagglutination Tests MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 670208 DP - 1965 Sep IS - 0042-4846 TA - Veterinariia PG - 28-30 CY - USSR IP - 9 VI - 42 JC - XCC EM - 6703 PMID- 5895852 CU - 85 TT - Ob etiologicheskom i epizootologicheskom znachenii leptospir iz serogruppy L. hebdomadis. SO - Veterinariia 1965 Sep;42(9):28-30 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66036485 AU - Corrias A TI - [Research on animal leptospirosis in Piedmont, with special reference to cattle breeding impaired by enzootic infertility (abortions, metritis, endometritis)] LA - Ita MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Female MH - Infertility, Female/*veterinary MH - Italy MH - Leptospirosis/*veterinary MH - Pregnancy PT - JOURNAL ARTICLE DA - 660117 DP - 1965 Sep IS - 0017-0321 TA - G Mal Infett Parassit PG - 519-25 CY - ITALY IP - 9 VI - 17 JC - FD7 EM - 6603 PMID- 5891442 CU - 88 TT - Ricerche sulle leptospirosi animali in Piemonte, con particolare riferimento agli allevamenti bovini copiti da infertilita enzootica (aborti, metriti, endometriti) SO - G Mal Infett Parassit 1965 Sep;17(9):519-25 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66036483 AU - De Stefano G AU - Ferrari A AU - Lombardo G TI - [Serologic research on diffusion of leptospirosis among horses] LA - Ita MH - Animal MH - Horse Diseases/*epidemiology MH - Horses MH - Italy MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 660117 DP - 1965 Sep IS - 0017-0321 TA - G Mal Infett Parassit PG - 510 CY - ITALY IP - 9 VI - 17 JC - FD7 EM - 6603 PMID- 5891441 CU - 88 TT - Ricerche sierologiche sulla diffusione della leptospirosi fra gli equini. SO - G Mal Infett Parassit 1965 Sep;17(9):510 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66036482 AU - Di Stefano G AU - Ferrari A AU - Lombardo G TI - [Serologic research on the diffusion of leptospirosis among cattle] LA - Ita MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Italy MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 660117 DP - 1965 Sep IS - 0017-0321 TA - G Mal Infett Parassit PG - 509 CY - ITALY IP - 9 VI - 17 JC - FD7 EM - 6603 PMID- 5891440 CU - 88 TT - Ricerche sierologiche sulla diffusione della leptospirosi fra i bovini. SO - G Mal Infett Parassit 1965 Sep;17(9):509 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67180333 AU - Sefer M TI - [Contributions to the study of the chemical constitution, the antigenic structure and the pathogenic power of leptospiras. 3. Isolation of the endotoxin. Relations between the complement-fixing common antigen and the endotoxin of leptospiras] LA - Fre MH - Animal MH - *Antigens MH - Complement Fixation Tests MH - *Endotoxins MH - *Leptospira MH - *Leptospirosis MH - Rabbits PT - JOURNAL ARTICLE DA - 670911 DP - 1965 Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 583-98 CY - ROMANIA IP - 3 VI - 24 JC - 8EM EM - 6710 PMID- 5877873 TT - Contributions a l'etude de la constitution chimique, de la structure antigenique et du pouvoir pathogene des leptospires. 3. Isolement de l'endotoxine. Relations entre l'antigene commun fixateur du complement et l'endotoxine des leptospires. SO - Arch Roum Pathol Exp Microbiol 1965 Sep;24(3):583-98 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67180332 AU - Sefer M TI - [Contributions to the study of the chemical constitution, the antigenic structure and the pathogenic power of leptospiras. II. Localization of the endotoxin in the anatomical and chemical structure of leptospiras] LA - Fre MH - Animal MH - Antigens/*analysis MH - Chemistry MH - Endotoxins/*analysis MH - *Leptospira MH - *Leptospirosis MH - Rabbits PT - JOURNAL ARTICLE DA - 670911 DP - 1965 Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 569-82 CY - ROMANIA IP - 3 VI - 24 JC - 8EM EM - 6710 PMID- 5877872 TT - Contributions a l'etude de la constitution chimique, de la structure antigenique et du pouvoir pathogene des leptospires. II. Localisation de l'endotoxine dans la structure anatomique et chimique des leptospires. SO - Arch Roum Pathol Exp Microbiol 1965 Sep;24(3):569-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67180331 AU - Sefer M TI - [Contributions to the study of the chemical constitution, the antigenic structure and the pathogenic power of leptospiras. I. Determination of the toxicity of leptospiras] LA - Fre MH - Animal MH - Fever MH - Guinea Pigs MH - Inflammation MH - Leptospira/*pathogenicity MH - *Leptospirosis MH - Rabbits MH - Skin Tests PT - JOURNAL ARTICLE DA - 670911 DP - 1965 Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 555-68 CY - ROMANIA IP - 3 VI - 24 JC - 8EM EM - 6710 PMID- 5877871 TT - Contributions a l'etude de la constitution chimique, de la structure antigenique et du pouvoir pathogene des leptospires. I. Determination de la toxicite des leptospires. SO - Arch Roum Pathol Exp Microbiol 1965 Sep;24(3):555-68 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [137 medline neighbors] UI - 67055042 AU - Soloshenko IZ AU - Chigirinskii AE AU - Semenova LP TI - [An experimental study of the susceptibility of small mammals to Leptospira of diverse serological types. 3. Morphological changes in the organs of albino mice caused by L. grippotyphosa and sejroe] LA - Rus MH - Animal MH - Leptospira/*pathogenicity MH - Leptospirosis/*pathology MH - Mice MH - Virulence PT - JOURNAL ARTICLE DA - 670225 DP - 1965 Sep TA - Zh Mikrobiol Epidemiol Immunobiol PG - 142-3 SB - M CY - USSR IP - 9 VI - 42 JC - Y9O EM - 6704 PMID- 5872298 CU - 89 TT - Eksperimental'noe izuchenie vospriimchivosti melkikh mlekopitaiushchikh k leptospiram razlichnykh serologicheskikh tipov. 3. Morfologicheskie izmeneniia v organakh belykh myshei, vyzyvaemye L. grippotyphosa i sejroe. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Sep;42(9):142-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66084226 AU - Amato Neto V AU - Magaldi C AU - Correa MO TI - [Diagnosis of leptospirosis by an agglutination test performed with serous fluids] LA - Por MH - Adult MH - *Agglutination Tests MH - Exudates and Transudates MH - Human MH - In Vitro MH - Leptospirosis/*diagnosis MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 660422 DP - 1965 Sep-Oct IS - 0036-4665 TA - Rev Inst Med Trop Sao Paulo PG - 267-9 CY - BRAZIL IP - 5 VI - 7 JC - S9D EM - 6606 PMID- 5860692 TT - Diagnostico de leptospiroses atraves de reacao de aglutinacao efetuada com liquidos de serosas. SO - Rev Inst Med Trop Sao Paulo 1965 Sep-Oct;7(5):267-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66037363 AU - Monteverde A AU - Annovazzi Lodi L TI - [Considerations on serodiagnostic positivity for leptospirosis in a group of 400 healthy full-time farmers of southern Novara] LA - Ita MH - Agricultural Workers' Diseases/*epidemiology MH - Female MH - Human MH - Italy MH - Leptospirosis/*epidemiology MH - Male MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 660120 DP - 1965 Sep IS - 0017-0321 TA - G Mal Infett Parassit PG - 511-7 CY - ITALY IP - 9 VI - 17 JC - FD7 EM - 6603 PMID- 5841000 CU - 88 TT - Considerazioni sulle positivita sierodiagnostiche per la leptospirosi in un gruppo di 400 coltivatori diretti sani del basso novarese. SO - G Mal Infett Parassit 1965 Sep;17(9):511-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66036545 AU - Krishnamurthi MV AU - Madanagopalan N AU - Hussain AT TI - Leptospirosis in Madras. LA - Eng MH - Case Report MH - Human MH - India MH - Leptospirosis/*epidemiology/pathology MH - Male MH - Middle Age MH - Weil's Disease/*diagnosis PT - JOURNAL ARTICLE DA - 660117 DP - 1965 Sep IS - 0004-5772 TA - J Assoc Physicians India PG - 737-40 CY - INDIA IP - 9 VI - 13 JC - HG7 EM - 6603 PMID- 5840523 CU - 88 SO - J Assoc Physicians India 1965 Sep;13(9):737-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66036487 AU - Fumagalli E TI - [Leptospirosis and hospital admission. (Findings in Novara from 1959 to 1964)] LA - Ita MH - Adolescence MH - Adult MH - Aged MH - Female MH - Hospitalization MH - Human MH - Italy MH - Leptospirosis/*epidemiology MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 660117 DP - 1965 Sep IS - 0017-0321 TA - G Mal Infett Parassit PG - 533-42 CY - ITALY IP - 9 VI - 17 JC - FD7 EM - 6603 PMID- 5840473 CU - 88 TT - Leptospirosi e spedalizzazione. (Rilievi Novaresi dal 1959 al 1964) SO - G Mal Infett Parassit 1965 Sep;17(9):533-42 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66036486 AU - Giubertoni C AU - Pisani C TI - [Clinical and electroencephalographic considerations on 11 cases of leptospiral meningitis] LA - Ita MH - Adolescence MH - Child MH - Electroencephalography MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Meningitis/*etiology PT - JOURNAL ARTICLE DA - 660117 DP - 1965 Sep IS - 0017-0321 TA - G Mal Infett Parassit PG - 527-31 CY - ITALY IP - 9 VI - 17 JC - FD7 EM - 6603 PMID- 5840472 TT - Considrazioni cliniche ed elettroencefalografiche su 11 casi di meningite da leptospire. SO - G Mal Infett Parassit 1965 Sep;17(9):527-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66036484 AU - Bosso G TI - [Leptospirosis infection in the etiology of uveitis] LA - Ita MH - Adolescence MH - Adult MH - Aged MH - Female MH - Human MH - Leptospirosis/*complications MH - Male MH - Middle Age MH - Uveitis/*etiology PT - JOURNAL ARTICLE DA - 660117 DP - 1965 Sep IS - 0017-0321 TA - G Mal Infett Parassit PG - 517-9 CY - ITALY IP - 9 VI - 17 JC - FD7 EM - 6603 PMID- 5840471 TT - L'infezione leptospirosica nell'etiologia dell'uveite. SO - G Mal Infett Parassit 1965 Sep;17(9):517-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67180345 AU - Radu I AU - Sturdza N AU - Radu A TI - [Studies of leptospiras by means of fluorescent antibodies. II. Demonstration of leptospiras in the body of the guinea pig infected with L. icterohaemorrhagiae] LA - Fre MH - Animal MH - *Fluorescent Antibody Technique MH - Guinea Pigs MH - Leptospira interrogans/*isolation & purification MH - *Leptospirosis PT - JOURNAL ARTICLE DA - 670911 DP - 1965 Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 713-26 CY - ROMANIA IP - 3 VI - 24 JC - 8EM EM - 6710 PMID- 5339437 CU - 90 TT - Etudes des leptospires au moyen des anticorps fluorescents. II. Mise en evidence des leptospires dans l'organisme du cobaye infecte par L. icterohaemorrhagiae. SO - Arch Roum Pathol Exp Microbiol 1965 Sep;24(3):713-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [106 medline neighbors] UI - 67055057 AU - Semenova LP TI - [A new serological subtype--L. pomona mozdok] LA - Rus MH - Leptospira/*classification MH - Russia PT - JOURNAL ARTICLE DA - 670225 DP - 1965 Sep TA - Zh Mikrobiol Epidemiol Immunobiol PG - 47-50 SB - M CY - USSR IP - 9 VI - 42 JC - Y9O EM - 6704 PMID- 4224674 CU - 92 TT - Novyi serologicheskii podtip--L. pomona mozdok. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Sep;42(9):47-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67055043 AU - Gol'denshtein ZA TI - [Leptospirosis incidence at meat processing plants] LA - Rus MH - Human MH - Leptospirosis/*epidemiology MH - *Meat-Packing Industry MH - Occupational Diseases/*epidemiology MH - Russia PT - JOURNAL ARTICLE DA - 670225 DP - 1965 Sep TA - Zh Mikrobiol Epidemiol Immunobiol PG - 143 SB - M CY - USSR IP - 9 VI - 42 JC - Y9O EM - 6704 PMID- 4224670 CU - 92 TT - O zabolevaemosti leptospirozom na predpriiatiiakh miasopererabatyvaiushchei promyshlennosti. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Sep;42(9):143 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66066678 AU - Farina R TI - [Frequency and diffusion in Italy of leptospiroses of domestic animals] LA - Ita MH - Animal MH - Italy MH - Leptospirosis/*epidemiology/*veterinary PT - JOURNAL ARTICLE DA - 660312 DP - 1965 Aug IS - 0017-0321 TA - G Mal Infett Parassit PG - 439-57 CY - ITALY IP - 8 VI - 17 JC - FD7 EM - 6605 PMID- 5892468 CU - 88 TT - Frequenza e diffusione in itali delle leptospirosi degli animali domestici. SO - G Mal Infett Parassit 1965 Aug;17(8):439-57 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66009538 AU - Iyer PK AU - Nanda YP TI - Observations on the "white spots" in the kidney of goats. LA - Eng MH - Animal MH - *Goats MH - In Vitro MH - India MH - Kidney Diseases/*veterinary MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 651202 DP - 1965 Aug IS - 0019-6479 TA - Indian Vet J PG - 567-70 CY - INDIA IP - 8 VI - 42 JC - GM9 EM - 6601 PMID- 5890476 CU - 85 SO - Indian Vet J 1965 Aug;42(8):567-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67002663 AU - Chernousova AV TI - [Eye lesions in leptospirosis] LA - Rus MH - Eye Diseases/*etiology MH - Human MH - Leptospirosis/*complications PT - JOURNAL ARTICLE DA - 661127 DP - 1965 Aug IS - 0023-2149 TA - Klin Med (Mosk) PG - 117-9 CY - USSR IP - 8 VI - 43 JC - KW2 EM - 6701 PMID- 5868512 TT - Porazheniia glaz v klinike leptospirozov. SO - Klin Med (Mosk) 1965 Aug;43(8):117-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 66066679 AU - Monteverde A AU - Gagliardi B TI - [Diagnostic and therapeutic aspects of human leptospirosis] LA - Ita MH - Human MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 660312 DP - 1965 Aug IS - 0017-0321 TA - G Mal Infett Parassit PG - 458-82 CY - ITALY IP - 8 VI - 17 JC - FD7 EM - 6605 PMID- 5852825 TT - Aspetti diagnostici o terapeutici della leptospirosi umana. SO - G Mal Infett Parassit 1965 Aug;17(8):458-82 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66066677 AU - Bianchi L TI - [On some microbiological and epidemiological aspects of leptospirosis] LA - Ita MH - Leptospira/*classification MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 660312 DP - 1965 Aug IS - 0017-0321 TA - G Mal Infett Parassit PG - 432-7 CY - ITALY IP - 8 VI - 17 JC - FD7 EM - 6605 PMID- 5852824 CU - 88 TT - Su alcuni aspetti microbiologici ed epidemiologici delle leptospirosi. SO - G Mal Infett Parassit 1965 Aug;17(8):432-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67085359 AU - Rostomian SV TI - [An experimental mixed leptospiral infection and a method of isolation of the initial cultures] LA - Rus MH - Animal MH - Bacteriological Techniques MH - Leptospira/*isolation & purification MH - Leptospirosis/diagnosis MH - Rabbits MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 670325 DP - 1965 Aug TA - Zh Mikrobiol Epidemiol Immunobiol PG - 111-7 SB - M CY - USSR IP - 8 VI - 42 JC - Y9O EM - 6705 PMID- 5334425 CU - 90 TT - Eksperimental'naia smeshannaia leptospiroznaia infektsiia i metod vydeleniia iskhodnykh kul'tur. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Aug;42(8):111-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [132 medline neighbors] UI - 66120897 AU - Alexander M AU - Kress HF von TI - [Convalescence following acute infectious diseases] LA - Ger MH - Adult MH - Case Report MH - Communicable Diseases/*therapy MH - *Convalescence MH - Enterovirus Infections/therapy MH - Hepatitis A/therapy MH - Human MH - Influenza/therapy MH - Leptospirosis/*therapy MH - Male MH - Rickettsia Infections/therapy PT - JOURNAL ARTICLE DA - 660714 DP - 1965 Aug IS - 0020-9554 TA - Internist (Berl) PG - 391-6 SB - M CY - GERMANY, WEST IP - 8 VI - 6 JC - GVX EM - 6609 PMID- 5326089 CU - 90 TT - Rekonvaleszenz nach akuten Infektionskrankheiten. SO - Internist (Berl) 1965 Aug;6(8):391-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [163 medline neighbors] UI - 66091204 AU - Smibert RM TI - A technique for the isolation of Leptospirae from contaminating microorganisms. LA - Eng MH - *Bacteriological Techniques MH - Filtration MH - In Vitro MH - Leptospira/*isolation & purification PT - JOURNAL ARTICLE DA - 660520 DP - 1965 Aug IS - 0008-4166 TA - Can J Microbiol PG - 743-4 SB - M CY - CANADA IP - 4 VI - 11 JC - CJ3 EM - 6607 PMID- 5324004 CU - 90 SO - Can J Microbiol 1965 Aug;11(4):743-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66082560 AU - Schroder HD TI - [On the demonstration of Leptospira using fluorescent antibody technic] LA - Ger MH - Animal MH - *Fluorescent Antibody Technique MH - In Vitro MH - Leptospira/*immunology MH - Rats PT - JOURNAL ARTICLE DA - 660421 DP - 1965 Aug 1 IS - 0026-9263 TA - Monatsh Veterinarmed PG - 631-4 CY - GERMANY, EAST IP - 15 VI - 20 JC - NGV EM - 6606 PMID- 5323755 CU - 90 TT - Zum Nachweis von Leptospiren mit fluoreszierenden Antikorpern. SO - Monatsh Veterinarmed 1965 Aug 1;20(15):631-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 66161097 AU - Nolaev IuE TI - [Etiology of animal leptospirosis] LA - Rus MH - Animal MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 661008 DP - 1965 Jul IS - 0042-4846 TA - Veterinariia PG - 29-31 CY - USSR IP - 7 VI - 42 JC - XCC EM - 6612 PMID- 5895079 CU - 85 TT - Etiologiia leptospiroza zhivotnykh. SO - Veterinariia 1965 Jul;42(7):29-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66161096 AU - Koliev MF AU - Fediushkin ME AU - Fediushkina TT TI - [Problems of local epizootology and of leptosirosis control] LA - Rus MH - Animal MH - Leptospirosis/*prevention & control/*veterinary MH - USSR PT - JOURNAL ARTICLE DA - 661008 DP - 1965 Jul IS - 0042-4846 TA - Veterinariia PG - 28-9 CY - USSR IP - 7 VI - 42 JC - XCC EM - 6612 PMID- 5895078 CU - 85 TT - Voprosy kraevoi epizootologii i bor'by s leptospirozom. SO - Veterinariia 1965 Jul;42(7):28-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66139894 AU - Karasevaev AU - Kokovin IL TI - [Observations on Leptospira popoma in field mice during the winter in North Osetia] LA - Rus MH - Animal MH - Leptospirosis/*epidemiology MH - Rodent Diseases/*epidemiology MH - *Seasons MH - USSR PT - JOURNAL ARTICLE DA - 660818 DP - 1965 Jul TA - Zh Mikrobiol Epidemiol Immunobiol PG - 89-93 SB - M CY - USSR IP - 7 VI - 42 JC - Y9O EM - 6610 PMID- 5894332 CU - 89 TT - Zemnie nabliudeniia za tsirukliatsiei leptospir tipa pomona sredi polevykh myshei b severnoi osetii. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Jul;42(7):89-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66093370 AU - Sova Z TI - [Relation between leptospiral infections and iridocyclochoroiditis in horses] LA - Ger MH - Animal MH - Choroiditis/*veterinary MH - Horse Diseases MH - Horses MH - In Vitro MH - Leptospirosis/*veterinary MH - Uveitis, Anterior/*veterinary PT - JOURNAL ARTICLE DA - 660521 DP - 1965 Jul TA - Zentralbl Bakteriol [Orig] PG - 100-10 SB - M CY - GERMANY, WEST IP - 1 VI - 197 JC - Y4Y EM - 6607 PMID- 5893215 CU - 89 TT - Die Beziehung leptospiroser Infektionen bei Pferden zur Iridocyklochorioiditis recidiva. SO - Zentralbl Bakteriol [Orig] 1965 Jul;197(1):100-10 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66036476 AU - Di Stefano G AU - Ferrari A AU - Lombardo G TI - [Serologic research on diffusion of leptospirosis among horses] LA - Ita MH - Animal MH - *Horse Diseases MH - Horses MH - Italy MH - Leptospirosis/*veterinary MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 660117 DP - 1965 Jul-Sep IS - 0017-0313 TA - G Ig Med Prev PG - 223-8 CY - ITALY IP - 3 VI - 6 JC - FB9 EM - 6603 PMID- 5891439 CU - 85 TT - Ricerche sierologiche sulla diffusione della leptospirosi tra gli equini. SO - G Ig Med Prev 1965 Jul-Sep;6(3):223-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66004959 AU - Babudieri B AU - Gaspardis D TI - The significance of low titers of leptospira agglutinins in the serum of apparently healthy cattle. LA - Eng MH - Animal MH - *Antibodies MH - Cattle MH - Cattle Diseases/*diagnosis MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 651120 DP - 1965 Jul TA - Zentralbl Veterinarmed [B] PG - 291-7 CY - GERMANY, WEST IP - 4 VI - 12 JC - Y72 EM - 6601 PMID- 5890143 CU - 89 SO - Zentralbl Veterinarmed [B] 1965 Jul;12(4):291-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66142103 AU - Drankin DI AU - Samuilo OI TI - [Epidemiologic outbreaks of swamp fever] LA - Rus MH - Human MH - Leptospirosis/*epidemiology MH - USSR MH - *Water Microbiology MH - *Water Pollution PT - JOURNAL ARTICLE DA - 660825 DP - 1965 Jul TA - Zh Mikrobiol Epidemiol Immunobiol PG - 93-9 SB - M CY - USSR IP - 7 VI - 42 JC - Y9O EM - 6610 PMID- 5884351 CU - 89 TT - K epidemiologii vspyshek vodnoi likhoradki. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Jul;42(7):93-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66142102 AU - Roshchipkin VI AU - Poberezkin MN AU - Zaitseva AA TI - [Leptospirosis canicola in a city of the Kuibyshev district] LA - Rus MH - Human MH - Leptospirosis/*epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 660825 DP - 1965 Jul TA - Zh Mikrobiol Epidemiol Immunobiol PG - 86-9 SB - M CY - USSR IP - 7 VI - 42 JC - Y9O EM - 6610 PMID- 5884350 CU - 89 TT - Leptospiroznye zebolevaniia tipa canicola v odnom iz gorodov Kuibyshevskoi oblasti. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Jul;42(7):86-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66076473 AU - Santa Rosa CA AU - Galton MM AU - Sulzer CR TI - Evaluation of a polyvalent Leptospiral vaccine in guinea pigs. LA - Eng MH - Animal MH - Evaluation Studies MH - Guinea Pigs MH - Leptospirosis/*immunology MH - Vaccination MH - *Vaccines PT - JOURNAL ARTICLE DA - 660409 DP - 1965 Jul IS - 0002-9645 TA - Am J Vet Res PG - 979-83 SB - M CY - UNITED STATES IP - 113 VI - 26 JC - 40C EM - 6606 PMID- 5857180 SO - Am J Vet Res 1965 Jul;26(113):979-83 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66048624 AU - Meira DA AU - Wainman JT AU - Pileggi F AU - Salles JC AU - Meira JA AU - Decourt LV TI - [Myocardial involvement in leptospirosis. Electrocardiographic and anatomo-pathological study] LA - Por MH - Adolescence MH - Adult MH - Child MH - Heart Diseases/*etiology MH - Human MH - Leptospirosis/*complications MH - Middle Age MH - Weil's Disease/*complications PT - JOURNAL ARTICLE DA - 660217 DP - 1965 Jun IS - 0066-782X TA - Arq Bras Cardiol PG - 177-94 CY - BRAZIL IP - 3 VI - 18 JC - 8PM EM - 6604 PMID- 5847726 TT - Comprometimento miocardico na leptospirose. Estudo electrocardiografico e anatomo-patologico. SO - Arq Bras Cardiol 1965 Jun;18(3):177-94 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66040926 AU - Pillot J AU - Ryter A TI - [Structure of spirochetes. 1. Study of the genera Treponema, Borrelia and Leptospira by the electron microscope] LA - Fre MH - Borrelia/*anatomy & histology MH - In Vitro MH - Leptospira/*anatomy & histology MH - Microscopy, Electron MH - Treponema/*anatomy & histology PT - JOURNAL ARTICLE DA - 660129 DP - 1965 Jun IS - 0020-2444 TA - Ann Inst Pasteur (Paris) PG - 791-804 SB - M CY - FRANCE IP - 6 VI - 108 JC - 58Y EM - 6604 PMID- 5843232 TT - Structure des spirochetes. 1. Etude des generes Treponema, Borrelia et Leptospira au microscope electronique. SO - Ann Inst Pasteur (Paris) 1965 Jun;108(6):791-804 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66034886 AU - Gervaise TI - [Apropos of a case of leptospirosis due to Leptospira hebdomalis] LA - Fre MH - Adolescence MH - Case Report MH - Female MH - Human MH - Leptospirosis/*etiology PT - JOURNAL ARTICLE DA - 660115 DP - 1965 Jun TA - J Med Bord PG - 1020-1 CY - FRANCE IP - 6 VI - 142 JC - J07 EM - 6603 PMID- 5839526 CU - 89 TT - A propos d'un cas de leptospirose a leptospira hebdomalis. SO - J Med Bord 1965 Jun;142(6):1020-1 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66003253 AU - Yu ES AU - Wu SY AU - Lee DF TI - Studies on the antagonism between different types of leptospira and on the method of detecting infections of two mixed types of leptospira. LA - Eng MH - Animal MH - Guinea Pigs MH - In Vitro MH - Leptospira/*growth & development/*isolation & purification MH - Leptospirosis/*immunology PT - JOURNAL ARTICLE DA - 651118 DP - 1965 Jun TA - Sci Sin PG - 901-12 CY - CHINA IP - 6 VI - 14 JC - UIU EM - 6601 PMID- 5826810 CU - 89 SO - Sci Sin 1965 Jun;14(6):901-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [199 medline neighbors] UI - 67176547 AU - Radu I AU - Iliesco M AU - Sturdza N TI - [Study of Leptospira by means of fluorescent antibodies. I. Serological studies with immunofluorescence compared with the agglutination-lysis test] LA - Fre MH - *Agglutination Tests MH - Antigens/*analysis MH - *Fluorescent Antibody Technique MH - Human MH - *Leptospira MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 670903 DP - 1965 Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 513-26 CY - ROMANIA IP - 2 VI - 24 JC - 8EM EM - 6710 PMID- 5339102 CU - 90 TT - Etude des leptospires au moyen des anticorps fluorescents. I. Recherches serologiques par l'immuno-fluorescence, comparativement a la reaction d' agglutination-lyse. SO - Arch Roum Pathol Exp Microbiol 1965 Jun;24(2):513-26 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [158 medline neighbors] UI - 66043064 AU - Elian M AU - Nicoara I TI - [The use of an antigen of the Patoc strain of Leptospira biflexa in field investigations of leptospirosis] LA - Spa MH - *Antigens MH - *Complement Fixation Tests MH - Human MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 660204 DP - 1965 Jun IS - 0030-0632 TA - Bol Oficina Sanit Panam PG - 498-502 CY - UNITED STATES IP - 6 VI - 58 JC - AGG EM - 6604 PMID- 4221169 CU - 92 TT - El empleo de un antigeno de la cepa Patoc de L. biflexa en investigaciones de campo sobre la leptospirosis. SO - Bol Oficina Sanit Panam 1965 Jun;58(6):498-502 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66060085 AU - Lataste-Dorolle C TI - [Serum anti-leptospira agglutinins in apparently normal cattle] LA - Fre MH - Animal MH - Cattle MH - Cattle Diseases/*immunology MH - Hemagglutination MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 660305 DP - 1965 May-Jun IS - 0300-9823 TA - Bull Off Int Epizoot PG - 891-905 CY - FRANCE IP - 5 VI - 63 JC - BR4 EM - 6605 PMID- 5892238 CU - 85 TT - Agglutinines antileptospires seriques chez les bovins apparemment normaux. SO - Bull Off Int Epizoot 1965 May-Jun;63(5):891-905 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [177 medline neighbors] UI - 66165802 AU - Chernukha IuG TI - [Serological properties of some strains of L. grippotyphosa] LA - Rus MH - Antigens MH - In Vitro MH - Leptospira/*immunology PT - JOURNAL ARTICLE DA - 661014 DP - 1965 May TA - Zh Mikrobiol Epidemiol Immunobiol PG - 133-7 SB - M CY - USSR IP - 5 VI - 42 JC - Y9O EM - 6612 PMID- 5887546 CU - 89 TT - Serologicheskie svoistva nekotorykh shtammov L. grippotyphosa. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 May;42(5):133-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66001366 AU - Mainzer W TI - [Occupational health problems in agriculture] LA - Heb MH - Agricultural Workers' Diseases/*epidemiology MH - Human MH - *Leptospirosis MH - *Parasitic Diseases MH - Parathion/*poisoning PT - JOURNAL ARTICLE DA - 651114 DP - 1965 May TA - Dapim Refuiim PG - 233-7 CY - ISRAEL IP - 3 VI - 24 JC - DZ7 EM - 6601 PMID- 5825784 CU - 89 SO - Dapim Refuiim 1965 May;24(3):233-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 66015972 AU - Mailloux M TI - [Notes on the epidemiology of leptospirosis] LA - Fre MH - Animal MH - Human MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE PT - REVIEW DA - 651218 DP - 1965 May-Jun IS - 0006-3266 TA - Biol Med (Paris) PG - 257-78 CY - FRANCE IP - 3 VI - 54 JC - BB0 EM - 6602 RF - 101 PMID- 4220737 CU - 92 TT - Notes sur l'epidemiologie des leptospiroses. SO - Biol Med (Paris) 1965 May-Jun;54(3):257-78 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66030151 AU - Di Stefano G AU - Ferrari A AU - Lombardo G TI - [Serologic research on diffusion of leptospirosis among cattle] LA - Ita MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Italy MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 660107 DP - 1965 Apr-Jun IS - 0017-0313 TA - G Ig Med Prev PG - 158-72 CY - ITALY IP - 2 VI - 6 JC - FB9 EM - 6603 PMID- 5891140 CU - 88 TT - Ricerche sierologiche sulla diffusione della leptospirosi fra i bovini. SO - G Ig Med Prev 1965 Apr-Jun;6(2):158-72 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 66168030 AU - Rostomian SV TI - [On antagonistic interrelations between Leptospira of various serological types] LA - Rus MH - Bacteriolysis MH - Hemagglutination Tests MH - Immune Sera MH - In Vitro MH - Leptospira/*growth & development MH - Leptospira canicola/*growth & development MH - Leptospira interrogans/*growth & development PT - JOURNAL ARTICLE DA - 661015 DP - 1965 Apr TA - Zh Mikrobiol Epidemiol Immunobiol PG - 69-73 SB - M CY - USSR IP - 4 VI - 42 JC - Y9O EM - 6612 PMID- 5887761 CU - 89 TT - Ob antagonisticheskikh vzaimootnosheniiakh mezhdu leptospirami razlichnykh serologicheskikh tipov. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Apr;42(4):69-73 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66168029 AU - Karaseva EV AU - Anan'in VV AU - Aguzarova MKh TI - [Experience in reducing the activity of natural leptospirosis foci] LA - Rus MH - Animal MH - Animals, Domestic MH - Disease Vectors MH - Human MH - Insecticides MH - Leptospirosis/*prevention & control/*veterinary MH - Rodentia MH - USSR PT - JOURNAL ARTICLE DA - 661015 DP - 1965 Apr TA - Zh Mikrobiol Epidemiol Immunobiol PG - 65-9 SB - M CY - USSR IP - 4 VI - 42 JC - Y9O EM - 6612 PMID- 5887760 CU - 89 TT - Opyt ponizheniia aktivnosti prirodnogo ochaga leptospiroza. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Apr;42(4):65-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [191 medline neighbors] UI - 66168028 AU - Semenova LP AU - Soloshenko IZ AU - Anan'in VV TI - [Leptospira of the hebdomadis group. 3. Detection of the subtype L. sejroe balcanica in the Soviet Union] LA - Rus MH - Animal MH - Cattle MH - Disease Vectors MH - Hemagglutination Tests MH - In Vitro MH - Leptospira/*isolation & purification MH - Swine MH - USSR PT - JOURNAL ARTICLE DA - 661015 DP - 1965 Apr TA - Zh Mikrobiol Epidemiol Immunobiol PG - 61-4 SB - M CY - USSR IP - 4 VI - 42 JC - Y9O EM - 6612 PMID- 5887759 CU - 89 TT - Leptospiry gruppy hebdomadis. Soobshchenie. 3. Obnaruzhenie v Sovetskom Soiuze podtipa L. sejroe balcanica. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Apr;42(4):61-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66168027 AU - Samedov AS AU - Akhmedova TM AU - Kosideeva SG TI - [Isolation of antigens from Leptospira by ultrasonic destruction] LA - Rus MH - *Antigens MH - Bacterial Proteins MH - Complement Fixation Tests MH - Immune Sera MH - In Vitro MH - Leptospira/*immunology MH - Ultrasonics PT - JOURNAL ARTICLE DA - 661015 DP - 1965 Apr TA - Zh Mikrobiol Epidemiol Immunobiol PG - 57-60 SB - M CY - USSR IP - 4 VI - 42 JC - Y9O EM - 6612 PMID- 5887758 CU - 89 TT - Vydelenie antigenov iz leptospir razrushennykh ul'trazvukom. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Apr;42(4):57-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [205 medline neighbors] UI - 66007298 AU - Sapiro-Hirsch R AU - Bassan H TI - [Leptospirosis canicolaris. The role of routine blood culture in the diagnosis of leptospirosis] LA - Heb MH - Human MH - Leptospirosis/*diagnosis PT - JOURNAL ARTICLE DA - 651125 DP - 1965 Apr TA - Dapim Refuiim PG - 139-41 CY - ISRAEL IP - 2 VI - 24 JC - DZ7 EM - 6601 PMID- 5829085 CU - 89 SO - Dapim Refuiim 1965 Apr;24(2):139-41 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66096409 AU - Duchassin M AU - Lataste-Dorolle C AU - Silverie CR TI - [Incidence of infection caused by L. icterohaemorrhagiae in rats in Cayenne. Some epidemiologic aspects of leptospirosis in French Guiana] LA - Fre MH - Animal MH - French Guiana MH - Guinea Pigs MH - Human MH - In Vitro MH - *Leptospira interrogans MH - Leptospirosis/*veterinary MH - Rabbits MH - Rats MH - Rodent Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 660522 DP - 1965 Mar-Apr IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 170-6 SB - M CY - FRANCE IP - 2 VI - 58 JC - C4G EM - 6607 PMID- 5898629 CU - 88 TT - Indice d'infection par L. icterohaemorrhagiae du rat de Cayenne. Quelques aspects epidemiologiques des leptospiroses en Guyane Francaise. SO - Bull Soc Pathol Exot Filiales 1965 Mar-Apr;58(2):170-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 69084401 AU - Varela G AU - Roch E TI - [Leptospirosis in the Republic of Mexico] LA - Spa MH - Animal MH - Animals, Domestic MH - Arthropod Vectors MH - Disease Reservoirs MH - Human MH - Leptospirosis/*epidemiology MH - Mexico PT - JOURNAL ARTICLE DA - 690225 DP - 1965 Mar-Apr IS - 0036-3634 TA - Salud Publica Mex PG - 189-93 CY - MEXICO IP - 2 VI - 7 JC - UY1 EM - 6904 PMID- 5896635 CU - 88 TT - Leptospirosis en la Republica Mexicana. SO - Salud Publica Mex 1965 Mar-Apr;7(2):189-93 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66133738 AU - Mefod'ev VV AU - Iastrebov AF TI - [Role of agricultural animals in the development of anthropo-pathogenic foci of leptospirosis] LA - Rus MH - Animal MH - Animals, Domestic MH - Disease Reservoirs MH - Human MH - Leptospirosis/*epidemiology MH - Zoonoses/*epidemiology PT - JOURNAL ARTICLE DA - 660731 DP - 1965 Mar TA - Zh Mikrobiol Epidemiol Immunobiol PG - 142 SB - M CY - USSR IP - 3 VI - 42 JC - Y9O EM - 6609 PMID- 5882769 CU - 89 TT - O roli sel'skokhoziaistvennykh zhivotnykh v formirovanii antropurgicheskikh ochagov leptospiroza. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Mar;42(3):142 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66133737 AU - Titrova AI AU - Shul'ts LM AU - Tel'bukh VP TI - [Comparative evaluation of the effectiveness of culture media for the growth of Leptospira] LA - Rus MH - *Culture Media MH - In Vitro MH - Leptospira/*growth & development PT - JOURNAL ARTICLE DA - 660731 DP - 1965 Mar TA - Zh Mikrobiol Epidemiol Immunobiol PG - 141 SB - M CY - USSR IP - 3 VI - 42 JC - Y9O EM - 6609 PMID- 5882768 CU - 89 TT - Sravnitel'naia otsenka effektivnosti pitatel'nykh sred dlia vyrashchivaniia leptospir. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Mar;42(3):141 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66133735 AU - Semenova LP TI - [Studies on Leptospira from the serological group pomona isolated from a natural focus] LA - Rus MH - Disease Reservoirs MH - In Vitro MH - *Leptospira MH - Leptospirosis PT - JOURNAL ARTICLE DA - 660731 DP - 1965 Mar TA - Zh Mikrobiol Epidemiol Immunobiol PG - 139-40 SB - M CY - USSR IP - 3 VI - 42 JC - Y9O EM - 6609 PMID- 5882766 CU - 89 TT - Izuchenie shtammov leptospir serologicheskoi gruppy pomona vydelennykh v prirodnom ochage. SO - Zh Mikrobiol Epidemiol Immunobiol 1965 Mar;42(3):139-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [209 medline neighbors] UI - 66090351 AU - Zardi O TI - [Epidemiology of leptospiroses] LA - Ita MH - Human MH - Italy MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 660519 DP - 1965 Mar-Apr IS - 0029-6287 TA - Nuovi Ann Ig Microbiol PG - 108-36 CY - ITALY IP - 2 VI - 16 JC - O90 EM - 6607 PMID- 5860881 CU - 88 TT - Epidemiologia delle leptospirosi. SO - Nuovi Ann Ig Microbiol 1965 Mar-Apr;16(2):108-36 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [187 medline neighbors] UI - 66075418 AU - Fuchs GH AU - Burger G TI - [Result-sequence-procedure (sequence analysis) in the investigation of Leptospira. I. The unilateral sequence test (Wald) for testing of the mean value of a binominal distribution] LA - Ger MH - In Vitro MH - Leptospira/*growth & development MH - Mathematics MH - Probability MH - Statistics PT - JOURNAL ARTICLE DA - 660408 DP - 1965 Mar TA - Zentralbl Bakteriol [Orig] PG - 523-35 SB - M CY - GERMANY, WEST IP - 4 VI - 195 JC - Y4Y EM - 6606 PMID- 5856759 CU - 89 TT - Das Ergebnisfolgeverfahren (Sequenzanalyse) in der Leptospirenforschung. SO - Zentralbl Bakteriol [Orig] 1965 Mar;195(4):523-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 66040278 AU - Mellino M AU - Wiel Marin A TI - [Further research on diffusion of leptospirosis in the province of Sassari] LA - Ita MH - Human MH - Italy MH - Leptospirosis/*epidemiology PT - JOURNAL ARTICLE DA - 660129 DP - 1965 Mar-Apr IS - 0017-0267 TA - G Batteriol Virol Immunol PG - 129-32 SB - M CY - ITALY IP - 3 VI - 58 JC - FA5 EM - 6604 PMID- 5842809 CU - 88 TT - Ulteriori ricerche sulla diffusione delle leptospirosi nella provincia di Sassari. SO - G Batteriol Virol Immunol 1965 Mar-Apr;58(3):129-32 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [146 medline neighbors] UI - 66010053 AU - Yanagihara Y AU - Mifuchi I TI - Studies on pathogenic leptospirae. II. Growth of pathogenic leptospirae by replacing rabbit serum with four strains of mycobacteria and other microorganisms. LA - Eng MH - Bacteria MH - Blood MH - Culture Media MH - In Vitro MH - Leptospira canicola/*growth & development MH - Leptospira interrogans/*growth & development MH - Mycobacterium PT - JOURNAL ARTICLE DA - 651202 DP - 1965 Mar IS - 0021-5139 TA - Jpn J Microbiol PG - 1-13 SB - M CY - JAPAN IP - 1 VI - 9 JC - KMF EM - 6601 PMID- 5294322 CU - 89 SO - Jpn J Microbiol 1965 Mar;9(1):1-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [193 medline neighbors] UI - 66049798 AU - Payet M AU - Pene P AU - Lataste Dorolle C AU - Bonnardot R AU - Bernou JC AU - Rahmi R TI - ["Hyos" leptospirosis in Dakar] LA - Fre MH - Africa, Western MH - Animal MH - Case Report MH - Human MH - Leptospirosis/*etiology MH - Male MH - Middle Age MH - Swine MH - *Swine Diseases MH - *Zoonoses PT - JOURNAL ARTICLE DA - 660219 DP - 1965 Jan-Feb IS - 0037-9085 TA - Bull Soc Pathol Exot Filiales PG - 54-9 SB - M CY - FRANCE IP - 1 VI - 58 JC - C4G EM - 6604 PMID- 5898055 CU - 86 TT - Leptospirose "Hyos" a Dakar. SO - Bull Soc Pathol Exot Filiales 1965 Jan-Feb;58(1):54-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69275153 AU - Castelli M TI - [Study of a phenomenon of agglutinability variation in leptospira strains of the Poi serotype] LA - Ita MH - *Agglutination Tests MH - Animal MH - *Antigens MH - Culture Media MH - English Abstract MH - Immune Sera MH - Leptospira/*classification/isolation & purification MH - Leptospirosis/diagnosis MH - Rabbits MH - Serotyping PT - JOURNAL ARTICLE DA - 691015 DP - 1965 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 129-63 SB - M CY - ITALY IP - 1 VI - 1 JC - 5BP EM - 6912 PMID- 5896830 CU - 85 TT - Studio di un fenomeno di variazione di agglutinabilita di ceppi di leptospire appartenenti al serotipo Poi. SO - Ann Ist Super Sanita 1965;1(1):129-63 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [175 medline neighbors] UI - 69251059 AU - Thomakos A AU - Babudieri B TI - [Serologic study of leptospires of the ballum type] LA - Ita MH - Agglutination Tests MH - Animal MH - *Antigens MH - English Abstract MH - Immune Sera MH - Leptospira/*classification MH - Rabbits MH - Serotyping PT - JOURNAL ARTICLE DA - 690919 DP - 1965 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 407-11 SB - M CY - ITALY IP - 7 VI - 1 JC - 5BP EM - 6911 PMID- 5896827 CU - 85 TT - Studio serologico delle leptospire appartenenti al tipo ballum. SO - Ann Ist Super Sanita 1965;1(7):407-11 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67007777 AU - Holota IaA AU - Karisheva AF AU - Chepurov KP AU - Prus OH TI - [Microscopy and cultivation in the study of leptospirosis in swine] LA - Ukr MH - Animal MH - Dogs MH - Guinea Pigs MH - Leptospirosis/*veterinary MH - Microscopy MH - Rabbits MH - Swine MH - *Swine Diseases PT - JOURNAL ARTICLE DA - 661203 DP - 1965 IS - 0026-3664 TA - Mikrobiol Zh PG - 42-5 CY - USSR IP - 4 VI - 27 JC - MZ2 EM - 6701 PMID- 5895726 CU - 85 TT - Mikroskopichni ta kul'tural'ni doslidzhennia pry leptospirozi svynei. SO - Mikrobiol Zh 1965;27(4):42-5 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [118 medline neighbors] UI - 66096017 AU - Chernukha YG TI - Serological classification of Soviet strains of leptospirae belonging to the serological group L. canicola). LA - Eng MH - Antigens MH - In Vitro MH - Leptospira canicola/*classification MH - Serology PT - JOURNAL ARTICLE DA - 660522 DP - 1965 IS - 0022-1732 TA - J Hyg Epidemiol Microbiol Immunol PG - 326-35 SB - M CY - CZECHOSLOVAKIA IP - 3 VI - 9 JC - IEV EM - 6607 PMID- 5893323 CU - 85 SO - J Hyg Epidemiol Microbiol Immunol 1965;9(3):326-35 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69275152 AU - Castellani Pastoris M TI - [Research on the phenomenon of specific agglutination of leptospira] LA - Ita MH - *Agglutination Tests MH - Centrifugation MH - Immune Sera MH - Leptospira/*classification MH - Serotyping PT - JOURNAL ARTICLE DA - 691015 DP - 1965 IS - 0021-2571 TA - Ann Ist Super Sanita PG - 124-8 SB - M CY - ITALY IP - 1 VI - 1 JC - 5BP EM - 6912 PMID- 5889620 TT - Ricerche sul fenomeno dell'agglutinazione specifica delle leptospire. SO - Ann Ist Super Sanita 1965;1(1):124-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66163223 AU - Parnas J AU - Cybulska M TI - Leptospira polonica--a new serotype. LA - Eng MH - Hemagglutination Tests MH - In Vitro MH - Leptospira/*classification/*immunology MH - Poland PT - JOURNAL ARTICLE DA - 661009 DP - 1965 IS - 0001-4087 TA - Bull Acad Pol Sci [Biol] PG - 505-7 CY - POLAND IP - 9 VI - 13 JC - B8W EM - 6612 PMID- 5887185 SO - Bull Acad Pol Sci [Biol] 1965;13(9):505-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66136680 AU - Yoshimori RN AU - Goldberg HS AU - Blenden DC TI - Cephalothin in the treatment of experimental leptospirosis in hamsters. LA - Eng MH - Animal MH - Cephalothin/*therapeutic use MH - Hamsters MH - In Vitro MH - Leptospira canicola/*drug effects MH - Leptospirosis/*drug therapy PT - JOURNAL ARTICLE DA - 660813 DP - 1965 IS - 0066-4804 TA - Antimicrob Agents Chemother PG - 450-2 CY - UNITED STATES VI - 5 JC - 6HK EM - 6610 PMID- 5883457 SO - Antimicrob Agents Chemother 1965;5:450-2 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66069258 AU - Kis' VV AU - Shugailo VT AU - Shakhnovskii NP TI - [Outbreak of anicteric leptospirosis in the Sborow district of the Tarnopol region] LA - Rus MH - Human MH - Leptospirosis/*epidemiology MH - Ukraine PT - JOURNAL ARTICLE DA - 660319 DP - 1965 Jan IS - 0049-6804 TA - Vrach Delo PG - 143-4 CY - USSR VI - 1 JC - XLS EM - 6605 PMID- 5853979 CU - 88 TT - Vspyshka bezzheltushnogo leptospiroza v zborovskom raione, ternopol'skoi oblasti. SO - Vrach Delo 1965 Jan;1:143-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [192 medline neighbors] UI - 66002046 AU - Witmer R TI - [Clinical picture of uveitis, laboratory diagnosis] LA - Ger MH - Blood Pressure Determination MH - Blood Protein Electrophoresis MH - Chorioretinitis/pathology MH - Choroiditis/pathology MH - Human MH - Leptospirosis/pathology MH - Radiography MH - Serodiagnosis MH - Skin Tests MH - Toxoplasmosis, Ocular/pathology MH - Uveitis/*diagnosis/pathology PT - JOURNAL ARTICLE DA - 651116 DP - 1965 IS - 0030-3755 TA - Ophthalmologica PG - 390-404 SB - M CY - SWITZERLAND IP - 5 VI - 149 JC - OIG EM - 6601 PMID- 5826173 TT - Klinik der Uveitis, Labordiagnostik. SO - Ophthalmologica 1965;149(5):390-404 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67022551 AU - Tomasic P TI - [Leptospira infections in Gradiska Bebrina] LA - Scc MH - Adolescence MH - Adult MH - Aged MH - Human MH - Leptospirosis/*epidemiology MH - Middle Age MH - Yugoslavia PT - JOURNAL ARTICLE DA - 670109 DP - 1965 TA - Hig Cas Hig Mikrobiol Epidemiol Sanit Teh PG - 57-60 CY - YUGOSLAVIA IP - 1 VI - 17 JC - G7R EM - 6702 PMID- 5296924 CU - 89 TT - Prokuzenost leptospirama u Gradiskoj Bebrini. SO - Hig Cas Hig Mikrobiol Epidemiol Sanit Teh 1965;17(1):57-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66009470 TI - Classification of leptospires and recent advances in leptospirosis. LA - Eng MH - In Vitro MH - Leptospira/*classification MH - *Leptospirosis PT - JOURNAL ARTICLE DA - 651202 DP - 1965 IS - 0042-9686 TA - Bull World Health Organ PG - 881-91 CY - SWITZERLAND IP - 6 VI - 32 JC - C80 EM - 6601 PMID- 5294312 CU - 89 NI - A SO - Bull World Health Organ 1965;32(6):881-91 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [75 medline neighbors] UI - 66112511 AU - Ellinghausen HC Jr AU - Sandvik O TI - Tributyrinase activity of leptospires: fixed and soluble tributyrinase demonstrated by means of an agar diffusion test. LA - Eng MH - *Immunodiffusion MH - In Vitro MH - Leptospira/*enzymology MH - *Lipase PT - JOURNAL ARTICLE DA - 660628 DP - 1965 TA - Acta Pathol Microbiol Scand PG - 259-70 SB - M CY - DENMARK IP - 2 VI - 65 JC - 1O0 EM - 6608 PMID- 4956226 CU - 91 SO - Acta Pathol Microbiol Scand 1965;65(2):259-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 69193376 AU - Buzas E AU - Ivanyi J TI - [Guiding principles in the differential diagnosis of jaundice in our clinical cases] LA - Ger MH - Adolescence MH - Adult MH - Age Factors MH - Aged MH - Aspartate Aminotransferase/blood MH - Bilirubin/blood MH - Child MH - Child, Preschool MH - Cholecystography MH - Chronic Disease MH - Diagnosis, Differential MH - Enzyme Tests MH - Female MH - Hepatitis/complications MH - Hepatitis A/blood/complications/*diagnosis/enzymology/epidemiology MH - Human MH - Hungary MH - Infant MH - Infant, Newborn MH - Jaundice/etiology MH - Laparotomy MH - Leptospirosis/complications MH - Male MH - Middle Age PT - JOURNAL ARTICLE DA - 690708 DP - 1964 Dec 20 IS - 0300-8673 TA - Z Allgemeinmed PG - 1509-12 CY - GERMANY, WEST IP - 35 VI - 40 JC - XSL EM - 6908 PMID- 5889480 CU - 88 TT - Richtlinien in der Differentialdiagnostik unseres Ikterus-Krankengutes. SO - Z Allgemeinmed 1964 Dec 20;40(35):1509-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66012370 AU - Sebek Z AU - Janicek B TI - [Occupational leptospiroses in Bohemia and Moravia] LA - Ger MH - Animal MH - Child MH - Child, Preschool MH - Czechoslovakia MH - Human MH - Infant MH - *Leptospira canicola MH - Leptospirosis/*epidemiology MH - Mice MH - Occupational Diseases/*epidemiology MH - Rats MH - Rural Health MH - Weil's Disease/*epidemiology MH - Zoonoses/prevention & control PT - JOURNAL ARTICLE DA - 651210 DP - 1964 Dec TA - Zentralbl Bakteriol [Orig] PG - 101-16 SB - M CY - GERMANY, WEST IP - 1 VI - 195 JC - Y4Y EM - 6602 PMID- 5890663 CU - 89 TT - Uber berufsbedingte Leptospirosen in Bohmen und Mahren. SO - Zentralbl Bakteriol [Orig] 1964 Dec;195(1):101-16 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66019948 AU - Topciu V AU - Spinu I TI - [Pathogenicity for guinea pigs of strains of Leptospira isolated from patients and convalescents in North Viet-Nam] LA - Fre MH - Animal MH - Guinea Pigs MH - Human MH - Leptospira/*isolation & purification/*pathogenicity MH - *Leptospirosis MH - Vietnam PT - JOURNAL ARTICLE DA - 651231 DP - 1964 Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 851-60 CY - ROMANIA IP - 4 VI - 23 JC - 8EM EM - 6602 PMID- 5836089 TT - Pathogenite pour le cobaye des souches de leptospires isolees des malades et des convalescents au Viet-Nam du Nord. SO - Arch Roum Pathol Exp Microbiol 1964 Dec;23(4):851-60 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [166 medline neighbors] UI - 66019957 AU - Sturdza N AU - Safiresco D TI - [On the stainability of Leptospira and Treponema] LA - Fre MH - In Vitro MH - *Leptospira MH - *Staining MH - *Treponema PT - JOURNAL ARTICLE DA - 651231 DP - 1964 Dec IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 927-38 CY - ROMANIA IP - 4 VI - 23 JC - 8EM EM - 6602 PMID- 4158160 CU - 95 TT - Sur la colorabilite des leptospires et des treponemes. SO - Arch Roum Pathol Exp Microbiol 1964 Dec;23(4):927-38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66014247 AU - Zardi O AU - Giorgi G TI - [Epidemiological studies on leptospirosis. Isolation and study of serotypes from dogs in the province of Parma] LA - Ita MH - Animal MH - Antibodies MH - *Dog Diseases MH - Dogs MH - Italy MH - Leptospira/isolation & purification MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 651213 DP - 1964 Nov-Dec IS - 0029-6287 TA - Nuovi Ann Ig Microbiol PG - 511-6 CY - ITALY IP - 6 VI - 15 JC - O90 EM - 6602 PMID- 5890779 CU - 85 TT - Studi epidemiologici sulla leptospirosi. Isolamento e studio di sierotipi da cani nella Provincia di Parma. SO - Nuovi Ann Ig Microbiol 1964 Nov-Dec;15(6):511-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66014248 AU - Zardi O TI - [Prophylaxis of leptospirosis] LA - Ita MH - Human MH - Leptospirosis/*prevention & control PT - JOURNAL ARTICLE DA - 651213 DP - 1964 Nov-Dec IS - 0029-6287 TA - Nuovi Ann Ig Microbiol PG - 517-31 CY - ITALY IP - 6 VI - 15 JC - O90 EM - 6602 PMID- 5832879 TT - Profilassi delle leptospirosi. SO - Nuovi Ann Ig Microbiol 1964 Nov-Dec;15(6):517-31 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66013552 AU - Gelev I TI - [Pathogenic properties of Leptospira diverticuli] LA - Ger MH - Agglutination Tests MH - Animal MH - Guinea Pigs MH - Leptospira/pathogenicity MH - *Leptospirosis MH - Rabbits MH - Swine PT - JOURNAL ARTICLE DA - 651211 DP - 1964 Nov TA - Zentralbl Bakteriol [Orig] PG - 374-8 SB - M CY - GERMANY, WEST IP - 3 VI - 194 JC - Y4Y EM - 6602 PMID- 5832434 CU - 89 TT - Uber die pathogenen Eigenschaften der Leptospira diverticuli. SO - Zentralbl Bakteriol [Orig] 1964 Nov;194(3):374-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68007444 AU - Crawford RP TI - Evaluation of a plate test for the detection of leptospiral antibodies in bovine serum. LA - Eng MH - Agglutination Tests MH - Animal MH - *Antibodies MH - Cattle MH - Cattle Diseases/*immunology MH - Leptospirosis/immunology/*veterinary PT - JOURNAL ARTICLE DA - 671215 DP - 1964 Oct 1 IS - 0003-1488 TA - J Am Vet Med Assoc PG - 683-7 SB - M CY - UNITED STATES IP - 7 VI - 145 JC - HAV EM - 6801 PMID- 5878585 SO - J Am Vet Med Assoc 1964 Oct 1;145(7):683-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [99 medline neighbors] UI - 67165166 AU - Zavka Nenci C AU - Pitzurra M TI - [On the possibility of growing leptospiral strains in Hanks lactalbumin medium] LA - Ita MH - Albumins/metabolism MH - *Culture Media MH - Leptospira/*growth & development/metabolism MH - Leptospira canicola/growth & development MH - Leptospira interrogans/growth & development PT - JOURNAL ARTICLE DA - 670803 DP - 1964 Sep 30 IS - 0037-8771 TA - Boll Soc Ital Biol Sper PG - 1065-7 SB - M CY - ITALY IP - 18 VI - 40 JC - ALS EM - 6709 PMID- 5876941 TT - Sulla possibilita di cultura di ceppi di leptospire di terreno di Hanks alla lattoalbumina. SO - Boll Soc Ital Biol Sper 1964 Sep 30;40(18):1065-7 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66009350 AU - Topciu V AU - Spinu I TI - [Contribution to the study of the effects of antibiotics on the formation of antibodies] LA - Fre MH - Antibody Formation/*drug effects MH - Chlortetracycline/*pharmacology MH - Human MH - Leptospirosis/*immunology MH - Penicillins/*pharmacology PT - JOURNAL ARTICLE DA - 651202 DP - 1964 Sep IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 731-40 CY - ROMANIA IP - 3 VI - 23 JC - 8EM EM - 6601 PMID- 5830288 TT - Contribution a l'etude des influences des antibiotiques dans l'elaboration des anticorps. SO - Arch Roum Pathol Exp Microbiol 1964 Sep;23(3):731-40 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 67052486 AU - Andrews RD AU - Ferris DH AU - Hanson LE AU - Reilly JR TI - Leptospirosis in a cattle-deer association. LA - Eng MH - Animal MH - *Artiodactyla MH - Cattle MH - *Cattle Diseases MH - Illinois MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 670221 DP - 1964 Aug TA - Zoonoses Res PG - 79-92 CY - UNITED STATES IP - 2 VI - 3 JC - YDK EM - 6704 PMID- 5895896 CU - 89 SO - Zoonoses Res 1964 Aug;3(2):79-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [153 medline neighbors] UI - 66005568 AU - Sova Z TI - [Febris grippotyphosa in horses, inapparent infections and iridocyclochoroditis. II.] LA - Ger MH - Animal MH - Choroiditis/*veterinary MH - Czechoslovakia MH - Diagnosis, Differential MH - Hepatitis/veterinary MH - *Horse Diseases MH - Horses MH - Leptospirosis/*veterinary MH - Serodiagnosis MH - Uveitis, Anterior/*veterinary PT - JOURNAL ARTICLE DA - 651120 DP - 1964 Jul TA - Zentralbl Bakteriol [Orig] PG - 239-48 SB - M CY - GERMANY, WEST IP - 2 VI - 193 JC - Y4Y EM - 6601 PMID- 5890195 CU - 89 TT - Febris grippotyphosa bei Pferden, inapparente Infektionen und Iridozyklochorioiditis. II. SO - Zentralbl Bakteriol [Orig] 1964 Jul;193(2):239-48 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66005567 AU - Sova Z TI - [An acute infectious disease of horses caused by Leptospira grippotyphosa] LA - Ger MH - Animal MH - Czechoslovakia MH - *Horse Diseases MH - Horses MH - Hyperbilirubinemia/etiology MH - Jaundice/etiology MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 651120 DP - 1964 Jul TA - Zentralbl Bakteriol [Orig] PG - 224-38 SB - M CY - GERMANY, WEST IP - 2 VI - 193 JC - Y4Y EM - 6601 PMID- 5890194 CU - 89 TT - Eine akute, durch Leptospira grippotyphosa hervorgerufene Infektionskrankheit der Pferde. I. SO - Zentralbl Bakteriol [Orig] 1964 Jul;193(2):224-38 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [186 medline neighbors] UI - 67175951 AU - Topciu V AU - Spinu I AU - Roman V TI - [Serological incidence of leptospirosis in personnel engaged in care of the animals of agro-zootechnical cooperatives and in workers of slaughter-houses of North Viet Nam] LA - Fre MH - *Abattoirs MH - Agricultural Workers' Diseases/*epidemiology MH - Human MH - Leptospirosis/*epidemiology MH - *Occupational Diseases MH - Vietnam PT - JOURNAL ARTICLE DA - 670902 DP - 1964 Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 519-28 CY - ROMANIA IP - 2 VI - 23 JC - 8EM EM - 6710 PMID- 5877486 CU - 88 TT - Incidence serologique de la leptospirose chez le personnel affecte aux soins des animaux des cooperatives agro-zootechniques et chez les ouvriers des abattoirs du Vietnam du Nord. SO - Arch Roum Pathol Exp Microbiol 1964 Jun;23(2):519-28 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 67175929 AU - Spinu I AU - Topciu V TI - [Results obtained in the treatment of acute human leptospirosis with antibiotics] LA - Fre MH - Chlortetracycline/*therapeutic use MH - Human MH - Leptospirosis/*drug therapy MH - Penicillins/*therapeutic use MH - Streptomycin/*therapeutic use MH - Weil's Disease/*drug therapy PT - JOURNAL ARTICLE DA - 670902 DP - 1964 Jun IS - 0004-0037 TA - Arch Roum Pathol Exp Microbiol PG - 337-44 CY - ROMANIA IP - 2 VI - 23 JC - 8EM EM - 6710 PMID- 5877475 TT - Resultats obtenus dans le traitement de la leptospirose aigue humaine avec des antibiotiques. SO - Arch Roum Pathol Exp Microbiol 1964 Jun;23(2):337-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66111399 AU - Semenova LP AU - Anan'in VV TI - Leptospira of the hebdomadis group. II] LA - Rus MH - Animal MH - Hemagglutination MH - Hungary MH - In Vitro MH - Leptospira/*isolation & purification MH - USSR PT - JOURNAL ARTICLE DA - 660626 DP - 1964 May TA - Zh Mikrobiol Epidemiol Immunobiol PG - 93-6 SB - M CY - USSR IP - 5 VI - 41 JC - Y9O EM - 6608 PMID- 5867087 CU - 89 TT - Leptospiry gruppy hebdomadis. II. SO - Zh Mikrobiol Epidemiol Immunobiol 1964 May;41(5):93-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [185 medline neighbors] UI - 66111398 AU - Korenberg EI TI - [Evaluation of the epizootic situation by pathological anatomical changes in Microtus in leptospirosis] LA - Rus MH - Animal MH - Disease Reservoirs MH - Kidney/*pathology MH - Leptospirosis/*pathology MH - *Rodent Diseases PT - JOURNAL ARTICLE DA - 660626 DP - 1964 May TA - Zh Mikrobiol Epidemiol Immunobiol PG - 87-92 SB - M CY - USSR IP - 5 VI - 41 JC - Y9O EM - 6608 PMID- 5867086 CU - 89 TT - Otsenka epizooticheskoi situatsii po patologoanatomicheskim izmeneniiam u polevok pri leptospiroze. SO - Zh Mikrobiol Epidemiol Immunobiol 1964 May;41(5):87-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [78 medline neighbors] UI - 66111396 AU - Chernukha IuG AU - Karaseva EV TI - [Leptospiral infections of the Lora type (australis serological group) in the Georgia SSR] LA - Rus MH - Animal MH - Disease Reservoirs MH - Georgia (Republic) MH - *Leptospirosis MH - Rodent Diseases/*epidemiology PT - JOURNAL ARTICLE DA - 660626 DP - 1964 May TA - Zh Mikrobiol Epidemiol Immunobiol PG - 77-81 SB - M CY - USSR IP - 5 VI - 41 JC - Y9O EM - 6608 PMID- 4222427 CU - 92 TT - Leptospiroznaia infektsiia tipa Lora (serologicheskaia gruppa australis) v gruzinskoi SSR. SO - Zh Mikrobiol Epidemiol Immunobiol 1964 May;41(5):77-81 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [113 medline neighbors] UI - 66063731 AU - Ogawa S TI - [Studies on the eye changes due to leptospirosis. 3. Experiment by the use of fluid obtained by destruction of the body of Leptospira (L)] LA - Jpn MH - Animal MH - Anterior Chamber/*drug effects MH - *Leptospira canicola MH - Rabbits MH - Vitreous Body/*drug effects PT - JOURNAL ARTICLE DA - 660308 DP - 1964 Feb IS - 0300-9203 TA - Nippon Ganka Gakkai Zasshi PG - 130-8 CY - JAPAN IP - 2 VI - 68 JC - 22O EM - 6605 PMID- 5892366 CU - 85 SO - Nippon Ganka Gakkai Zasshi 1964 Feb;68(2):130-8 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 67134162 AU - Remky H TI - [Will leptospiral uveitis become an out-of-date disease?] LA - Fre MH - Adult MH - Female MH - Human MH - *Leptospirosis MH - Male MH - Middle Age MH - Uveitis/*microbiology PT - JOURNAL ARTICLE DA - 670620 DP - 1964 IS - 0081-0746 TA - Bull Soc Belge Ophtalmol PG - 437-44 CY - BELGIUM VI - 138 JC - BYO EM - 6708 PMID- 5875573 TT - L'uveite a leptospires serait-elle une maladie perimee? SO - Bull Soc Belge Ophtalmol 1964;138:437-44 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66090662 AU - Koslak A TI - [Analysis of Leptospira strains belonging to a standard collection (WHO) and that of a collection of Polish strains with the complement fixation test (OWD)] LA - Pol MH - Antigens MH - Complement Fixation Tests MH - In Vitro MH - Leptospira/*isolation & purification PT - JOURNAL ARTICLE DA - 660519 DP - 1964 IS - 0066-2240 TA - Ann Univ Mariae Curie Sklodowska [Med] PG - 263-70 CY - POLAND VI - 19 JC - 69M EM - 6607 PMID- 5861032 TT - Analiza szczepow leptospir kolekcji wzorcowej (WHO) oraz szczepow kolekcji krajowej przy pomocy odczynu wiazania dopelniacza (OWD) SO - Ann Univ Mariae Curie Sklodowska [Med] 1964;19:263-70 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [180 medline neighbors] UI - 66011841 AU - Parnas J AU - Koslak A AU - Krukowska-Cybulska M TI - [Epidemiological fight against an endemic leptospirosis] LA - Ger MH - Animal MH - Animal Diseases/prevention & control MH - Hemagglutination Tests MH - Human MH - Leptospirosis/*prevention & control MH - Mice MH - Poland MH - Rats MH - Vaccination PT - JOURNAL ARTICLE DA - 651208 DP - 1964 TA - Z Hyg Infektionskr PG - 142-50 CY - GERMANY, WEST IP - 2 VI - 150 JC - XVS EM - 6602 PMID- 5831626 CU - 89 TT - Die epidemiologische Bekampfung einer endemischen Leptospirose. SO - Z Hyg Infektionskr 1964;150(2):142-50 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [196 medline neighbors] UI - 66011837 AU - Cramer H TI - [Fluorescence serological demonstration of antibodies against Leptospira with a formalin antigen] LA - Ger MH - Animal MH - *Fluorescent Antibody Technique MH - Formaldehyde MH - In Vitro MH - Leptospira canicola/*immunology MH - Leptospira interrogans/*immunology MH - Rabbits PT - JOURNAL ARTICLE DA - 651208 DP - 1964 TA - Z Hyg Infektionskr PG - 108-13 CY - GERMANY, WEST IP - 2 VI - 150 JC - XVS EM - 6602 PMID- 5319050 CU - 90 TT - Fluorescenzserologischer Nachweis von Antikorpern gegen Leptospiren mit Hilfe eines formolisierten Antigens. SO - Z Hyg Infektionskr 1964;150(2):108-13 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66096265 AU - Solorzano RF TI - A comparison of the rapid macroscopic slide agglutination test with the microscopic slide agglutination test for leptospirosis. LA - Eng MH - *Agglutination Tests MH - Animal MH - Cattle MH - Comparative Study MH - Dogs MH - Horses MH - In Vitro MH - Leptospirosis/*veterinary MH - Swine PT - JOURNAL ARTICLE DA - 660522 DP - 1964 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 440-4 CY - UNITED STATES VI - 68 JC - PY5 EM - 6607 PMID- 5217533 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1964;68:440-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66096264 AU - Crawford RP TI - Evaluation of a plate test for detection of leptospiral antibodies in bovine serum. LA - Eng MH - *Agglutination Tests MH - Animal MH - Cattle MH - Cattle Diseases/*diagnosis MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 660522 DP - 1964 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 434-9 CY - UNITED STATES VI - 68 JC - PY5 EM - 6607 PMID- 5217532 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1964;68:434-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66096220 TI - Report of the Committee on Leptospirosis. LA - Eng MH - Animal MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 660522 DP - 1964 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 153-4 CY - UNITED STATES VI - 68 JC - PY5 EM - 6607 PMID- 5217494 CU - 88 NI - A SO - Proc Annu Meet U S Anim Health Assoc 1964;68:153-4 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [202 medline neighbors] UI - 66096219 AU - Morter RL AU - Herschler RC AU - Fessler JF AU - Lavignette A TI - Experimental equine leptospirosis (Leptospira pomona). LA - Eng MH - Animal MH - *Horse Diseases MH - Horses MH - In Vitro MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 660522 DP - 1964 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 147-52 CY - UNITED STATES VI - 68 JC - PY5 EM - 6607 PMID- 5217493 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1964;68:147-52 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66096218 AU - Hanson LE AU - Mansfield ME AU - Andrews RD TI - Epizootiology of enzootic leptospirosis in a cattle herd. LA - Eng MH - Animal MH - Cattle MH - Cattle Diseases/*epidemiology MH - Hemagglutination Tests MH - Illinois MH - In Vitro MH - Leptospirosis/*veterinary PT - JOURNAL ARTICLE DA - 660522 DP - 1964 IS - 0082-8750 TA - Proc Annu Meet U S Anim Health Assoc PG - 136-46 CY - UNITED STATES VI - 68 JC - PY5 EM - 6607 PMID- 5217492 CU - 88 SO - Proc Annu Meet U S Anim Health Assoc 1964;68:136-46 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 68324272 AU - Yamamoto S AU - Fujiwara K AU - Ito S TI - Studies on distribution of leptospires among dogs in Hokkaido. LA - Eng MH - Animal MH - Dog Diseases/*epidemiology MH - Dogs MH - Japan MH - Leptospira canicola/isolation & purification MH - Leptospirosis/*veterinary MH - Serodiagnosis PT - JOURNAL ARTICLE DA - 680905 DP - 1963 Feb IS - 0021-5295 TA - Nippon Juigaku Zasshi PG - 1-3 CY - JAPAN IP - 1 VI - 25 JC - KRJ EM - 6810 PMID- 5896527 CU - 88 SO - Nippon Juigaku Zasshi 1963 Feb;25(1):1-3 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [183 medline neighbors] UI - 66012791 AU - Tokarevich KN AU - Gopina AI AU - Popova EM AU - Silina NI TI - [Outbreak of swamp fever of the pomona type caused by bathing] LA - Rus MH - Adolescence MH - Animal MH - Child MH - Child, Preschool MH - Human MH - Leptospirosis/*epidemiology/*etiology MH - Swine MH - *Swine Diseases MH - USSR MH - *Water Pollution MH - *Zoonoses PT - JOURNAL ARTICLE DA - 651210 DP - 1963 TA - Tr Leningr Inst Epidemiol Mikrobiol PG - 286-92 CY - USSR VI - 25 JC - VXE EM - 6602 RO - M:CNR PMID- 5890700 LR - 901219 CU - 89 TT - Kupal'naia vspyshka vodnoi likhoradki tipa Pomona. SO - Tr Leningr Inst Epidemiol Mikrobiol 1963;25:286-92 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [208 medline neighbors] UI - 66014905 AU - Popova EM AU - Lesnikov AL TI - [Leptospirosis of the Tarassow type] LA - Rus MH - Human MH - Leptospirosis/*epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 651215 DP - 1963 TA - Tr Leningr Inst Epidemiol Mikrobiol PG - 305-12 CY - USSR VI - 25 JC - VXE EM - 6602 RO - M:CNR PMID- 5833309 LR - 901219 CU - 89 TT - Leptospiroz tipa tarasoza. SO - Tr Leningr Inst Epidemiol Mikrobiol 1963;25:305-12 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66012793 AU - Popova EM TI - [Some biologic aspects of Leptospira sorex isolated from Rattus rattus L] LA - Rus MH - Animal MH - Guinea Pigs MH - In Vitro MH - Leptospira/*isolation & purification MH - *Rats PT - JOURNAL ARTICLE DA - 651210 DP - 1963 TA - Tr Leningr Inst Epidemiol Mikrobiol PG - 313-9 CY - USSR VI - 25 JC - VXE EM - 6602 RO - M:CNR PMID- 5832124 LR - 901219 CU - 89 TT - Nekotorye biologicheskie svoistva leptospir tipa Soreks, vydelennykh ot Rattus rattus L. SO - Tr Leningr Inst Epidemiol Mikrobiol 1963;25:313-9 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [203 medline neighbors] UI - 66012790 AU - Tokalova KA AU - Popova EM AU - Sushkevich NI TI - [Results of further investigation of leptospirosis infections in the Kaliningrad region] LA - Rus MH - Human MH - Leptospirosis/*epidemiology MH - USSR PT - JOURNAL ARTICLE DA - 651210 DP - 1963 TA - Tr Leningr Inst Epidemiol Mikrobiol PG - 277-85 CY - USSR VI - 25 JC - VXE EM - 6602 RO - M:CNR PMID- 5832123 LR - 901219 CU - 89 TT - Rezul'taty dal'neishego izucheniia leptospiroznoi infektsii v Kaliningradskoi oblasti. SO - Tr Leningr Inst Epidemiol Mikrobiol 1963;25:277-85 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [201 medline neighbors] UI - 66012789 AU - Tokarevich KN AU - Timofeeva SS AU - Popova EM TI - [Data on leptospirosis in the Arctic region (preliminary report)] LA - Rus MH - *Cold Climate MH - Human MH - Leptospirosis/*epidemiology MH - Siberia PT - JOURNAL ARTICLE DA - 651210 DP - 1963 TA - Tr Leningr Inst Epidemiol Mikrobiol PG - 270-6 CY - USSR VI - 25 JC - VXE EM - 6602 RO - M:CNR PMID- 5832122 LR - 901219 CU - 89 TT - Materialy o letospirozakh v Zapoliar'e (predvaritel'noe soobschenie) SO - Tr Leningr Inst Epidemiol Mikrobiol 1963;25:270-6 ---------------------------------------------------------------------------- Other Formats: [Citation Format] Links: [200 medline neighbors] UI - 66012792 AU - Lesnikov AL AU - Popova EM TI - [Leptospiral diseases complicated by meningitis] LA - Rus MH - Human MH - Leptospirosis/*complications MH - Meningitis/*etiology PT - JOURNAL ARTICLE DA - 651210 DP - 1963 TA - Tr Leningr Inst Epidemiol Mikrobiol PG - 293-304 CY - USSR VI - 25 JC - VXE EM - 6602 RO - M:CNR PMID- 4952954 LR - 901219 CU - 89 TT - Leptospiroznye zabolevaniia, oslozhnennye meningitom. SO - Tr Leningr Inst Epidemiol Mikrobiol 1963;25:293-304