Chelenge study - Timetable

Chellenge study, 1999.

I did not put all the tests in the experiment because I think we shall discuss it first. I do not know if I can perform all that I would like to.

GROUP 1 & 2 INTRANASAL AND INTRAVAGINAL INFECTION (7 HEIFERS, NEGATIVE ON BLV)
Days | Samples to be taken | Tests | Response
-5 | blood and urine | mat all serovars + isolation from urine + ELISA BLV | FEEDBACK
-4 |  |  |
-3 |  |  |
-2 |  |  |
-1 | blood | mat | FEEDBACK
1 | Intranasal inoculation - I will scratch the nasal plane with sharp fabric and then spray it with hardjo. I will also spray nasal cavity. The procedure will be repeated three days. Intravaginal inoculation of 10 ml of culture to anterior vagina with plastic pipette.
2 |  |  |
3 |  |  |
4 |  |  |
5 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
6 |  |  |
7 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
8 |  |  |
9 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
10 |  |  |
11 |  |  |
12 |  |  |
13 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
14 |  |  |
15 |  |  |
16 |  |  |
17 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
18 |  |  |
19 |  |  |
20 |  |  |
21 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
22 |  |  |
23 |  |  |
24 |  |  |
25 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
26 |  |  |
27 |  |  |
28 |  |  |
29 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
30 |  |  |
31 |  |  |
32 |  |  |
33 |  |  |
34 |  |  |
35 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
36 |  |  |
37 |  |  |
38 |  |  |
39 |  |  |
40 |  |  |
41 |  |  |
42 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
43 |  |  |
44 |  |  |
45 |  |  |
46 |  |  |
47 |  |  |
48 |  |  |
49 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK
50 |  |  |
51 |  |  |
52 |  |  |
53 |  |  |
54 |  |  |
55 |  |  |
56 | blood, urine, vag. mucus (VM), nasal mucus (NM), milk, saliva | mat, wb-blood, milk, nasal mucus, saliva and vaginal mucus | FEEDBACK

I did not put all the tests in the experiment because I think we shall discuss it first. I do not know if I can perform all that I would like to.